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] |
indicated a lack of evolution in the optical-UV spectral properties redward of Ly$\alpha$ [@pentericci2003; @vandenberk2001]. At higher energies, the optical/IR -to-X-ray flux ratios [e.g. @brandt2002; @strateva2005] and X-ray continuum shapes [@vignali2003] show at most mild evolution from low redshift. However @jiang2010 have recently reported hot-dust-free quasars at $z\sim6$ which have no counterparts in the more local Universe. These quasars are thought to be at an early evolutionary stage, and offer the first evidence that quasar properties have evolved since the reionization era.
As yet, the spectral energy distribution blueward of the Lyman limit, which is critical for studies of reionization, is not measured at $z\sim6$ since the quasar spectra are subject to complete absorption. In the future the EUV spectral index could be measured from 21cm observations of the thickness of ionizing fronts of the HII regions around high redshift quasars [@kramer2008]. However in the meantime the assumed value of the spectral index is usually based on direct observations of the EUV spectrum of quasars at $z\la1$, where they are not subject to absorption from the IGM.
In this paper we show that the extent of Ly$\alpha$ transmission regions around high redshift quasars is sensitive to the EUV spectral index, and so provides a probe of this otherwise hidden portion of the spectrum. Our paper is presented in the following parts. We first summarise quasar near-zones (§ \[nearzone\]), the observed near-zone relation (§ \[obs\]), and our associated numerical modelling (§ \[NZ\]). We then present constraints on the relation between near-zone size, quasar redshift, and quasar luminosity (§ \[results\]). In § \[HIIregion\] and § \[EUV\] we present a discussion of the astrophysical interpretation of our results. As part of our analysis we provide a revised estimate of the ionizing background at $z=6$ and jointly constrain the ionizing background and EUV spectral index. Some additional uncertainties in our modeling are discussed in § \[other\], and our conclusions are presented in § \[conclusion\]. In our numerical examples, we adopt the standard set of cosmological parameters [@komatsu2009], with values of $\Omega_{\rm b}=0.044$, $\Omega_{\rm m}=0.24$ and $\Omega_{\Lambda}=0.76$ for the matter, baryon, and dark energy fractional density respectively, and $h=0.72$, for the dimensionless Hubble constant.
Near-zones {#nearzone}
==========
In view of the difficulty of determining the physical conditions of the quasar environment, as well as the observational challenges associated with measuring the [Ly$\alpha$]{} transmission at high redshift, @fan2006 defined a specific radius, hereafter referred to as the [*near-zone*]{} radius, at which the normalised [Ly$\alpha$]{} transmission drops to 10 per cent after being smoothed to a resolution of 20Å. This value of 10 per cent is arbitrary, and is chosen to be larger than the average Gunn-Peterson transmission in $z\simeq 6$ quasar spectra ($<4$ per cent). In order to make the measurement unambiguous, the near-zone radius is defined at the point where the transmission [*first*]{} drops below this level, even if it rises back above 10% at larger radii. The measured near-zone radius is therefore dependent on the spectral resolution.
{width="13cm"}
@fan2006 found a striking relation between near-zone size and redshift, which they quantify using the expression $$\label{nzrel}
R_{\rm p} = R_{\rm cor} + A\times (z-6).$$ Here the near-zone size, $R_{\rm cor}$, has been corrected for luminosity according to the relation $$R_{\rm corr} = R_{27} \times 10^{-0.4(27+M_{\rm 1450})/ B},$$ where $B=3$ and $R_{27}$ is the mean size of a near-zone at $z=6$ around a quasar of $M_{\rm 1450}=-27$. The value of $ B=3$ [which is roughly consistent with observations, @carilli2010] is motivated by the evolution of an HII region [@haiman2002] $$\begin{aligned}
\label{HII}
\nonumber
R_{\rm p} &=& 4.2 f_{\rm HI}^{-1/3}\left(\frac{\dot{N}}{1.9\times10^{57}\mbox{s}^{-1}}\right)^{1/3}\\
&&\hspace{10mm}\times\left(\frac{t}{10^7\mbox{yr}}\right)^{1/3}\left(\frac{1 + z}{7}\right)^{-1}\mbox{Mpc},\end{aligned}$$ where $f_{\rm HI}$ is the fraction of hydrogen that is neutral, $\dot{N}$ is the rate of ionizing photons produced by the quasar, and $t$ is the quasar age[^1]. The size of the near-zones is found to increase by a factor of 2 over the redshift range from $6.4>z>5.7$, from which @fan2006 inferred the neutral fraction to increase by an order of magnitude over that time.
On the other hand, if the near-zone size is set by resonant absorption in an otherwise ionized IGM rather than by the boundary of an HII region, then its value is instead approximated by the expression $$\begin{aligned}
\label{nz}
\nonumber
R_{\rm p} &\sim&\frac{3.1}{\Delta_{\rm lim}} \left(\frac{\tau_{\rm lim}}{2.3}\right)^{1/2}\left(\frac{T}{2\times10^4\mbox{K}}\right)^{0.35}\left(\frac{\dot{N}}{1.9\times10^{57}\mbox{s}^{-1}}\right)^{1/2}\\
&&\hspace{10mm}\times\left(\frac{\alpha^{-1}[\alpha+3]}{3}\right)^{-1/2}\left(\frac{1 + z}{7}\right)^{-9/4}\mbox{Mpc},\end{aligned}$$ where $\Delta_{\rm lim}$ is the normalised baryon density in the transmitting regions as a fraction of the cosmic mean ($\tau_{\rm lim}=2.3$, corresponding to the 10 per cent transmission), and $T$ is the IGM temperature [@bolton2007b]. The parameter $\alpha$ is the EUV spectral index. Equation (\[nz\]) differs from equation (\[HII\]) in three important ways. Firstly, if near-zone size is set by resonant absorption then it is not sensitive to the quasar lifetime. Secondly, resonant absorption results in a power-law index describing the dependence of near-zone size on luminosity with a value of $ B=2$ rather than $ B=3$. Thirdly, the near-zone size is sensitive to $\alpha$, suggesting that near-zone size provides an opportunity to measure this unknown parameter.
The precise definition of near-zone radius suggested by @fan2006 allows for quantitative comparison with simulations. @wyithe2008 and @bolton2010 have modelled near-zones using hydro-dynamical simulations with radiative transfer, combined with a semi-analytic model for the evolving, density dependent ionizing background. The modelling in the latter work is able to produce both the amplitude and evolution of the near-zone sizes, as well as the statistics of absorption lines within the near-zone, and is based on quasars in a highly ionized IGM. In this regime it is equation (\[nz\]) with $B=2$, rather than equation (\[HII\]) with $B=3$ that is applicable. This indicates that a varying ionizing background could be responsible for the observed relation, providing an alternative scenario to a strongly evolving neutral fraction. Unfortunately, this scenario implies that the evolution of quasar near-zones cannot necessarily be used to infer an evolution in neutral fraction. Thus, although intriguing, it could be argued that the observed near-zone relation has not yet taught us anything concrete about reionization.
When discussing near-zones most authors have concentrated on the relation between size and redshift, with measured size corrected for luminosity dependence as part of this process. In most cases these studies used the scaling of near-zone in proportion to luminosity to the one third power [e.g. @fan2006; @carilli2010]. As described above this value is appropriate if the near-zone is expanding into a neutral IGM. On the other hand, a power of one half ($B=2$) is more appropriate if the near-zone corresponds to a radius where resonant absorption in an ionized IGM results in the 10 per cent transmission [@bolton2007]. Thus the correct scaling between near-zone radius and quasar luminosity is uncertain. In this work we therefore treat the power-law index $B$ as a free parameter in a 2-dimensional relation describing near-zone radius as a function of quasar luminosity and redshift. We find that current near-zone data places strong constraints on the value of $ B$. Moreover, rather than focus on the interpretation of the parameter $A$ with respect to the end of hydrogen reionization, in this paper we concentrate instead on understanding the implications of the parameters $B$ and $R_{27}$ for the EUV spectral index blueward of the Lyman limit for $z\sim6$
|
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only when constitutional to do so under either Tinker or Bethel. See West, 23 F.Supp.2d at 1235. Specifically, the Latta Middle School dress code prohibits clothing that "distract[s] others, interfere[s] with the instructional programs, or otherwise cause[s] disruption," and specifically lists "anything deemed to be offensive" as an example of the type of distracting, interfering, or disrupting clothing banned under the dress code. (Am. Compl. ¶ 11, Doc. # 18). Because the dress code is written to target only clothing that causes disruption or interference in accordance with the standard set forth in Tinker, the Court does not find the dress code legally overbroad. See id.; see also B.W.A., 508 F.Supp.2d at 750-51 (holding that a dress code containing language that "tracks Tinker" does not pose a real danger of reaching a substantial amount of constitutionally protected speech). By prohibiting "shirts with obscene/derogatory sayings," the Latta High School dress code is sufficiently narrow. See Bethel Sch. Dist. No. 403 v. Fraser, 478 U.S. 675, 686, 106 S.Ct. 3159, 92 L.Ed.2d 549 (1986) (holding that a student's suspension for violating a school disciplinary rule which proscribed `obscene' language did not violate his right to due process when combined with the student's own knowledge of the rule). For these reasons, this Court does not conclude that the plaintiff has sufficiently shown that the dress codes of Latta Middle and High School were unconstitutionally overbroad. To the extent that the plaintiff's claims can be construed as an asapplied challenge to the dress codes, this claim also fails for the above noted reasons.
Finally, this Court concludes that the plaintiff did not lack adequate notice of the ban on Confederate clothing so as to render either dress code unconstitutionally vague. A government regulation may be declared unconstitutionally void for vagueness if it fails to give a person adequate warning that his conduct is prohibited, or if it fails to set out adequate standards to prevent arbitrary and discriminatory enforcement. See West, 23 F.Supp.2d at 1235 (citing Kolender v. Lawson, 461 U.S. 352, 357, 103 S.Ct. 1855, 75 L.Ed.2d 903 (1983)). In the public school context, a school policy or disciplinary rule might be void for vagueness if a reasonable student *745 of ordinary intelligence who read the policy could not understand what conduct it prohibited. See Broadrick v. Oklahoma, 413 U.S. 601, 608, 93 S.Ct. 2908, 37 L.Ed.2d 830 (1973). In her deposition, the plaintiff admitted she was aware of the school district's ban on Confederate flag clothing in February of 2004 while she attended Latta Middle School. (Pl.'s Dep. 72:10-16). Further, the allegations in the Amended Complaint indicate that the plaintiff was asked to remove shirts depicting the Confederate flag on numerous occasions before finally being disciplined for failing to comply with a request to remove a t-shirt depicting the Confederate flag. (Am. Compl. ¶¶ 16-21, Doc. # 18). Thus, the record illustrates that the plaintiff had notice that the Middle School's dress code applied to Confederate flag clothing before any disciplinary action was taken against the plaintiff. Courts have noted that "[s]uch a state of mind is inconsistent with any claim that the policy did not give plaintiff fair warning that [her] conduct was prohibited." West, 23 F.Supp.2d at 1235; see also Bethel, 478 U.S. at 686, 106 S.Ct. 3159 (noting that a teacher's verbal warning gave a student adequate notice of how a school ban on "obscene language" would be enforced). The Court concludes that the applicable dress codes put students on notice of what was prohibited. See Broadrick, 413 U.S. at 608, 93 S.Ct. 2908. School officials are entitled to a "certain degree of flexibility" in enforcing policies that discipline "a wide range of unanticipated conduct," and school disciplinary rules "need not be as detailed as a criminal code." Bethel, 478 U.S. at 686, 106 S.Ct. 3159. The record reflects that the dress codes, as enforced, were neither facially overbroad under the First Amendment nor unconstitutionally vague. Therefore, the defendants are entitled to summary judgment as to this claim.
IV. Claims Arising Under the South Carolina Constitution
In her final ground, the plaintiff alleges that the defendants violated her rights to freedom of speech and expression pursuant to the South Carolina Constitution. (Am. Compl., Doc. # 18). The parties have identified no precedent suggesting that the South Carolina Constitution affords "broader protections in the area of public student free speech than the United States Constitution." Governor Wentworth Reg. Sch. Dist., 421 F.Supp.2d 410, 425 (D.N.H.2006). Because the defendants are entitled to summary judgment on the plaintiffs First and Fourteenth Amendment claims under the United States Constitution, the defendants are likewise entitled to summary judgment as to the plaintiffs claim under the South Carolina Constitution.
CONCLUSION
For the reasons set forth herein, the defendants' motion for summary judgment is GRANTED. (Doc. # 120).
IT IS SO ORDERED.
NOTES
[1] The notice of appeal was dismissed as moot on November 15, 2007.
[2] It also appears that the plaintiff attended Latta High School for a portion of the 2008-09 school year. (Doc. # 120).
[3] These "protest" t-shirts did not actually display the Confederate flag (Pl.'s Ex. "H," "M," "U" "T," and "K," Doc. # 1). Prior to this Court's resolution of the plaintiff's motion for a preliminary injunction (Doc. # 60), the defendants agreed to permit the plaintiff to wear these "protest" shirts. Therefore, these "protest" t-shirts are not in dispute, and thus, not before the Court at this time. This Order addresses only the t-shirts which display the Confederate flag in whole or part including plaintiff's exhibit "R" (Jesus and the Confederate Battle Flag) (Doc. # 1).
[4] It appears from the testimony that these fights occurred at a former location of Latta Middle School prior to a relocation of the school to its current location.
Q:
How to execute gp.execute ArcSDE tool in C#
So I created an ArcGIS 10 toolbox in ArcSDE and added a tool to it.
There are enough examples out there on how to execute a tool.tbx that resides outside SDE or GeoDB.
But in C#, how do you use gp.execute on a tool that resides within ArcSDE?
thanks!
A:
Try using the IToolboxWorkspace interface. Code below works for a file gdb workspace, I'd imagine it would work for arcsde too.
private static void ListToolboxes(IWorkspace ws)
{
var tbxWkspc = ws as ESRI.ArcGIS.Geoprocessing.IToolboxWorkspace;
if (tbxWkspc == null)
{
Console.WriteLine("not a toolbox workspace");
return;
}
var toolboxes = tbxWkspc.Toolboxes;
toolboxes.Reset();
IGPToolbox tbx;
while ((tbx = toolboxes.Next())!= null)
{
var tools = tbx.Tools;
tools.Reset();
IGPTool tool;
while ((tool = tools.Next())!= null)
{
// you could execute here...
//tool.Execute
Console.WriteLine("{0}: {1}", tbx.PathName, tool.Name);
}
}
}
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Saturday, November 14, 2009
This is the last of the bottoms for the wardrobe contest! Originally I was going to do some crop pants with this fabric, but I'm a little out of time to try to fit another pair of pants. Also, the other brown skirt I made is a bit dressier, so I thought a casual skirt to go with all the tops would make a great addition. I'm wearing this top with the skirt.
I can't
|
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] |
igo CBD.
Associated crimes, including shoplifting, have reduced in recent weeks following an increased police presence in busy areas.
Senior Sergeant John Dalton said the answer to deter crime was simple - be seen.
In recent weeks crews have set up a mobile police van in shopping strips and community hubs, including Hargreaves Mall, Marketplace Shopping Centre and the Bendigo Railway Station.
It follows increased anti-social behaviour and crime in recent months.
"Not only does the visible police presence act as a clear deterrent, but it also becomes another option for people to report crimes, lost property or any other concerns they may have," he said.
"This simple approach provides the people of Bendigo with the reassurance that they can go about their shopping and rail travel without feeling uncomfortable or unsafe caused by the unacceptable behaviour of some people in these areas."
Senior Sergeant Dalton said there was clear evidence that police presence in populated areas had discouraged those thinking about causing trouble.
"We have had a great response from our shopkeepers with a number of them saying that their instances of shoplifting has been reduced since the introduction of our mobile police station and increased police presence," he said.
The mobile police van - one of many being used across the state - has also been operated by Protective Services Officers at the railway station.
It was all about breaking down barriers between residents and officers, Senior Sergeant Dalton said.
"The mobile police station has provided us with the opportunity to go to the community, rather than them having to come to us to report matters or ask for advice."
He said police would continue to use the facility at times when and where it was needed.
Members have also been handing out brochures to the public which include advice on reducing the chances of being a victim of burglaries, theft from motor cars and other crimes.Hardie ruled out of Autumn Test campaign
17 Nov Hardie ruled out of Autumn Test campaign
Back-row John Hardie has been ruled out of the remainder of Scotland’s 2016 Autumn Test campaign through injury.
The 13-times capped Edinburgh Rugby loose forward had corrective surgery at Spire Murrayfield Hospital today (Thursday) on the ankle he sprained during the national team’s narrow loss to Australia last weekend.
He will return to the care of his club’s medical team and is expected to be out of action for up to eight weeks.Teaching Personnel is working in partnership with a multi-trust academy which oversees the work of two Special Schools. The academy has been recognised as outstanding in its last three inspections. We know what outstanding looks like and what it takes to get there and stay there. The staffs have developed some fantastic practices and we are continually striving to further develop the learning opportunities we provide for the children.
Purpose of the post
To complement the professional work of teachers by supporting learning activities, in line with the School policies and guidance. This will involve supporting learning activities for individuals/ groups or for whole classes. It will involve supporting assessment, recording and reporting on achievement, behaviour for learning, progress and development.
Organise appropriate learning environments and resources
Within an agreed system of supervision support teaching and learning activities for individuals, groups or the whole class
Monitor and evaluate pupil responses to learning activities through a range of assessment and monitoring strategies against defined learning intentions
Record learning using a range of mechanisms
Provide objective and accurate feedback as required on pupil achievement, progress and other matters, ensuring the availability of appropriate evidence
Why work for us?
Training and Development opportunities
School is part of multi academy trust - Team building
School direct programmes to become a teacher or a therapist
Clear path for career progression
Competitive Salary
Supportive SLT, SEN department and parents and governors
State of the art facilities
If you are looking to join a dedicated team in a school that will welcome your ideas and aim to re-engage the young children, we would like to hear from you. Don't miss out on this amazing opportunity, send your updated CV and covering letter to the email address provided.
All applicants will require the appropriate qualifications and training for this role. Please see teachingpersonnel.com/faqs for details.
All pay rates quoted will be inclusive of 12.07% statutory holiday pay.
Teaching Personnel is committed to safeguarding and promoting the welfare of children. All candidates must undertake or have undertaken a valid enhanced Disclosure and Barring Service (DBS) check. Full assistance provided..Text_typography_display-s {
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Wednesday, April 16, 2008
That's The Best You Can Do?
What's with Conservatives, both the leadership and the minions- any negative coverage, any criticism from any organization, all part of some Liberal conspiracy? When an environmental group criticizes the government's policies, we are presented with "well we know they support the Liberals". When any columnist pens a negative piece, "it's the Liberal media at it again". When the Conservative Party breaks the law, the only thing that matters, Elections Canada is in co hoots with the Liberals. Predictable, and entirely lame:
The bigger concern was that media cameras were present Tuesday when the Mounties were entering and leaving the party's offices, said Finance Minister Jim Flaherty.
"I do find it odd, when I look at a photograph this morning and I see someone knocking on the door with cameras, with news cameras present," Flaherty said as he left a Conservative caucus meeting on Parliament Hill.
Yes Jim, the "bigger concern" isn't the raid itself, the legal implications, the stench of scandal, no it's the cameras. Okay.
More:
Ottawa-area Conservative Pierre Poilievre took it further, accusing Elections Canada of offering the Liberal party front-row seats to watch the raid unfold.
"Somebody should ask who in Elections Canada invited the Liberal party to make a home video out of the visit to our headquarters," he said.
Or, somebody should ask why Elections Canada was forced to ask the RCMP to intervene, why they felt it necessary to get a search warrant? That's a good question, maybe even more relevant that why the Liberals witnessed the sorry display.
The accusation doesn't deserve merit, but Kady shoots it full of holes here. This line of defence is akin to the Cadman scandal, where all the Tories could do was infer the tape had been doctored. When you have nothing substantive in defence, the only recourse is too attempt to blur the lines, offering juvenile doubt, try and smear the messenger.
It's a sad day, when the Conservatives try to sully Elections Canada, question their independence, make it appear to be a partisan conspiracy. Conservative supporters should be embarrassed, that their leadership forever employs the scorched earth policy, when reasonable questions are asked. In trying to discredit, they undermine confidence in our institutions, institutions which have a job to do, their independence above reproach.
Yes, what were the Liberals doing there, is Elections Canada in bed with the opposition? Canadians demand answers. That't the best you can do? Pathetic.
"But while most Conservative MPs were publicly impugning the motives of Elections Canada officials, some of them privately questioned the wisdom of their own party officials, particularly the director of political operations, Doug Finley. Finley was the backroom commander during the 2006 general election campaign and will perform the same function in the next campaign. Some Conservative MPs criticized him and the party's legal advisers for being too aggressive in "pushing the envelope" so far as Canada's elections laws are concerned.
In their view, a decision by party officials to take a hard line against Elections Canada and the elections commissioner precipitated the RCMP move. These Conservatives say they believe their cause is just but they worry that, even if they do prevail, voters will only remember the pictures of police officers at their headquarters.
"Did anybody think about the optics of this thing?" asked a Conservative official."Abiotic stress induced miRNA-TF-gene regulatory network: A structural perspective.
MicroRNAs (miRNAs) and transcription factors (TFs) are the largest families of trans-acting gene regulatory species, which are pivotal players in a complex regulatory network. Recently, extensive research on miRNAs and TFs in agriculture has identified these trans-acting regulatory species, as an effective tool for engineering new crop cultivars to increase yield and quality as well tolerance to environmental stresses but our knowledge of regulatory network is still not sufficient to decipher the exact mechanism. In the current work, stress-specific TF-miRNA-gene network was built for Arabidopsis under drought, cold, salt and waterlogging stress using data from reliable publically available databases; and transcriptome and degradome sequence data analysis by meta-analysis approach. Further network analysis elucidated significantly dense, scale-free, small world and hierarchical backbone of interactions. The various centrality measures highlighted several genes/TF/miRNAs as potential targets for tolerant variety cultivation. This comprehensive regulatory information will accelerate the advancement of current understanding on stress specific transcriptional and post-transcriptional regulatory mechanism and has promising utilizations for experimental biologist who are intended to improve plant crop performance under multiple Ab
|
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it becomes less likely all the changes were due to chance or confounds. Most theories predict relatively broad effects for their independent variables. Hackman and Oldham's (1980) theory of work design, for example, holds that the more skills a job requires, the extent to which a worker does a complete task rather than just part of it, the more important the task, the more independence the worker has, and the more feedback the worker has on the quality of the work, the higher will be work motivation, job satisfaction, and work effectiveness. A case study test of an implementation of the theory could therefore assess three dependent variables, two of which are psychological states and the third of which is behavioral.
**_Multiple sources of information_.** The single-case researcher should try to use as many sources of information as possible for each dependent variable (Yin, 2009). McKee et al. (2009) conducted a case study of football players whose untimely deaths appeared to be related to neurological deterioration stemming from repeated brain trauma when they were active players. The researchers' analysis included variables such as number of years of play and age of symptom onset, as well as the presence of early indicators of brain damage, such as mood disorders and memory loss. They also verified the actual brain damage using autopsies. It is also sometimes possible to get information about an individual from several people who have opportunities to observe the person. Ollendick (1981), for example, studied the effectiveness of a treatment for reducing the occurrence of a child's tics by having both the child's mother and teacher keep records of occurrences. However, researchers should be careful to ensure that all informants are unbiased and are providing reliable assessments (Achenbach, 2006). Official records can also be a source of information. For example, businesses keep records of costs, productivity, and rates of employee turnover and absences; the first two provide direct indicators of work effectiveness, and the last two can be used as indirect indicators of job satisfaction and motivation. Artifacts—things that people produce either intentionally or unintentionally—can provide physical evidence of the effect of an independent variable. For example, wastage of raw materials is a negative indicator of work effectiveness in manufacturing: the more waste, the less effective the work. Finally, documents other than official records, such as letters, news reports, even graffiti, can be a source of information. Graffiti, for example, could be used as an indicator of the level of morale in a factory. Personal documents, such as letters, diaries, or blogs offer a snapshot of everyday life in a specific time period. As we noted in Chapter 6 in the discussion of multiple operationism, the more sources of evidence that are available about the effect of an independent variable and the greater the extent to which the different sources of evidence lead to the same conclusion, the more confidence we can have in the conclusions drawn from the research.
**_Frequent assessment_.** Finally, the more often the dependent variable is assessed during the research, the easier it is to rule out some alternative explanations. For example, if assessments are made only at the beginning and end of a study, then history or maturation could account for any changes observed over the course of the study. However, if the study concerns an intervention, then assessments can be made before the intervention, during the course of the intervention, and following the intervention. Such continuous data collection allows you to determine if change is associated with the onset of the intervention, thus reducing the likelihood of a history confound. The data also allow assessment of the impact criteria described below, helping to rule out maturation as an alternative explanation. The use of continuous assessment requires careful selection of sources of information. Highly intrusive measures, such as questionnaires and physiological measures, might induce reactivity that could threaten the validity of the study. Consequently, observations and records might be better suited as sources of information for more frequent assessments.
##### **Replication Criteria**
In Chapter 5, we showed that replication is an important tool in research, helping to determine the generalizability and limits of research findings. Replication cases should be as different from each other as possible (heterogeneous) rather than similar to each other (homogeneous; Kratochwill et al., 1984). Successful replication across a diverse set of cases demonstrates the robustness of a phenomenon, and failures to replicate can be compared to successful replications to determine the boundary conditions of a phenomenon. Research on the success of an educational innovation, for example, might include urban, suburban, and rural schools to determine if the innovation is effective for different populations of children. Clinical research would seek heterogeneity on both patient variables, such as sex, ethnicity, and socioeconomic status, and therapist variables, such as level of experience. To the extent that the hypothesis is supported across these variations in case characteristics, the results are more generalizable.
**FIGURE 13.1**
**Replicated Case Study Research.**
Cases are selected to test the generalizability of findings.
Yin (2009) has developed a model for replicated case study research, shown in Figure 13.1, that can also be applied to single-case experiments. Following the model discussed in Chapter 5, researchers use theory to develop a set of hypotheses. These hypotheses provide a basis for selecting cases that can provide data to test them and a basis for determining the dependent variables to use and the best sources of information for each dependent variable. The researchers then conduct the case studies and write up the results for each study. Finally, the researchers compare the results across the cases to draw conclusions about the hypothesis and to determine the implications of those conclusions for theory and application.
##### **Control Criteria**
A major objection to case study research is that it is impossible to assess the impact of an independent variable because there is no control or comparison condition to use as a baseline.
However, as Yin (2009) points out, a situation analogous to the experimental and control conditions of experimental research can be achieved by including both **test cases** and **control cases** in case study research. A test case, like the experimental condition in an experiment, allows the researcher to observe what happens when the independent variable is present and so could have an effect on the dependent variable. A control case, like the control condition in an experiment, allows the researcher to observe what happens in the absence of the independent variable. A comparison of the two types of cases helps rule out many threats to internal validity, as does the comparison of the experimental to the control condition in an experiment. Just as a complete test of a hypothesis in experimental research might require more than one control group, so might case study research require more than one control case.
Yin (1994) gives the example of a case study test of the hypothesis that when computers are used in school districts for both administrative and instructional purposes, then the overall rate of computer usage will increase, but that the use of computers for either purpose alone will have no effect. As shown in Table 13.2, a complete test of this hypothesis requires that at least three cases be compared: one in which computers are used for both administrative and instructional purposes, one in which computers are used for administration only, and one in which computers are used for instruction only. Only if all three predictions shown in Table 13.2 are borne out will the hypothesis be fully supported.
**TABLE 13.2**
Use of Replication in Case Study Research to Test a Hypothesis
_Hypothesis_ : Joint instructional and administrative use of computers in a school district leads to increasing use of computers over time.
---
**Case** | **Role in Study** | **Prediction**
Joint use of computers | Test case | Increase in computer use
Administrative use only | Control case | No increase in computer use
Instructional use only | Control case | No increase in computer use
_Note_ : Based on Yin, 1994.
Control cases can also help the researcher discriminate among possible explanations for a phenomenon. For example, Szanton (1981) studied attempts by university-based and non-university groups to help cities deal with urban problems. One set of studies demonstrated that university-based groups were unable to help cities solve a variety of problems. A second set of studies showed that non-university-based groups also failed to help cities, demonstrating that the failures in the first group of cases were probably not due to the academic location of the advisers. A third set of studies showed that university groups had been successful in helping private enterprise, demonstrating that university-based advisers could be successful. A final group of studies dealt with university groups that had been successful in advising cities, comparing these cases to the failure cases to identify boundary conditions that limit the success of university-based advice to city governments.
It is important to bear in mind that the use of control cases is not always desirable. For example, the use of control cases in clinical research raises the same ethical concerns as the use of no-treatment control groups that we discussed in Chapter 3. In both situations, the researcher must carefully weigh the value of the knowledge to be gained from a control condition or case against the potential harm that could arise from leaving a problem untreated.
##### **Impact Criteria**
In treatment-outcome research, the magnitude of the impact that a treatment has is an indicator of the degree to which history, maturation, and statistical regression might be threats to the validity of the research (Kazdin, 2011): The greater the impact of a treatment, the less likely the change is due to these factors. Kratochwill et al. (1984) list three indicators of impact. A treatment is more likely to be the cause of a change in a chronic problem than an acute problem. Chronicity is itself an indicator that maturation is not affecting the problem, because the problem has not ameliorated over time without intervention. A large impact is more indicative of possible
|
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] |
becomes a sanctuary of unrivaled comfort and taste. Lower the split-folding rear seats to create up to 66cu. ft. of cargo space or, when equipped with third-row seats for two, the driver can share the journey with up to six passengers. Other features include available panoramic glass moonroof and rear seat DVD player with 8 inch screen. With a single twin-scroll turbocharger the xDrive35i will perform 300hp and 300 lb-ft of torque. Generating 413lb. ft. of torque with 255hp, an inline-six Advanced Diesel engine is available on the xDrive35d. A 4.8L V8 engine yields 445hp and 479 lb-ft of torque on the xDrive50i. The M Power V8 Turbo comes from the M performance division giving the X5 M an impressive 555hp. With BMW Assist, you have an emergency switchboard, navigation system, and information service, all in one on an integrated touchscreen. A premium Harman Kardon system puts the power of 11 speakers at your disposal. Using BMW Apps you can extend the communication and entertainment of your X5 with tailor-made applications. Source: The Manufacturer Summary * Long list of standard features; cutting-edge technology; seductive style. Source: Edmunds
I understand that BMW NA and\/or an authorized dealer may send me offers or information about their products and services at my phone number listed above. By checking this box, I agree to receive such offers and information via automated technology, such as autodialed text or phone messages. I understand that my consent is not required as a condition of purchase.*
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I understand that BMW NA and\/or an authorized dealer may send me offers or information about their products and services at my phone number listed above. By checking this box, I agree to receive such offers and information via automated technology, such as autodialed text or phone messages. I understand that my consent is not required as a condition of purchase.*The present invention relates to a vehicle armrest and particularly one which moves in two planes as it is extended from a compact storage position to a use position.
Armrests typically pivot between a raised position to a lowered use position in a vertical plane. The armrest occupies the area immediately adjacent the side of the seat back when in a retracted stored position and rotates in a single axis and in a vertical plane to a lowered use position. In vans and particularly mini-vans, it is desirable to allow room between front seats such that a person can move from the front of the vehicle to the rear area of the vehicle. Conventional armrests severely restrict such access.
Also, with the advent of today's relatively compact vehicles, the space between front seats typically cannot easily accommodate a pair of armrests, with one each for the driver and passenger sides, let alone a pair of armrests which have a width which provides comfortable support of one's forearm. Thus, single armrests are usually provided or the armrests are relatively narrow and therefore uncomfortable.
Further, in many vehicles, a parking brake lever extends between the front seats and an armrest can interfere with its operation when lowered. In order to overcome the latter problem, an armrest is disclosed in Offenlegungsschrift DE 3432084 A1 published on Mar. 13, 1986, which pivots downwardly from a seat back and then rotates outwardly to present a concave edge which faces the seat occupant. A linear edge is spaced from an adjacent armrest of mirror image construction to provide access to a parking brake control lever. Although such a design provides for two plane movement of an armrest between storage and use positions, it does not provide easy control for the user nor does it provide an armrest of a substantially uniform width along its length for providing comfortable support for a persons arm.Q:
Inverse limit of Hopfalgebras
My Question relates to Corollary 2.7 of
http://www.jmilne.org/math/xnotes/tc.pdf
So Let $k$ be a field and $\mathbb{G}_i$ be an projective system of affine $k$-groupschemes.
I want to know if the inverse limit in the category of affine $k$-groupschemes is the same as the inverse limit in the category of the affine k-schemes, i.e. if the corresponding inductive limit of the $k$-Hopfalgebras (Deligne calls them Bialgebras in the link above) is the inductive limit of $k$-Algebras.
More precisely i want to know if there is an isomorphism (of groups or of sets) between the inverse limit of $k$-rational points and the $k$-rational points of the inverse limit, i.e.
$(\underset{\leftarrow}{\lim}\mathbb{G}_i)(k)\cong\underset{\leftarrow}{\lim}(\mathbb{G}_i(k))$.
And if that is not the case, is there at least a canonical morphism between those two.
A:
From the definition of limit we have $\text{Hom}(A,\lim B_i) \cong \lim \text{Hom}(A,B_i)$. This holds in any category. In particular, your final equation is certainly true (as an iso of sets).
Moreover, I feel like an argument of the form "limits commute with limits" ought to show that it is an iso of groups as well (because the definition of group object involves some limits), but I'm doing math on an empty stomach, so I'm not too sure. I apologize.
EDIT:
It's abstract nonsense. Given a complete category $C$, and denoting the associated cat of groups $D$, and the forgetful functor by $F{:}C \rightarrow D$, you can take the limit $\lim F G_i$ and endow it with a group structure in such a way that the maps $\lim FG_i \rightarrow FG_i$ become group homomorphisms, from which it follows that $F$ preserves limits.
For instance, let $f,g{:}G \rightarrow H$ be group homomorphisms and $E \rightarrow G$ their equalizer in $C$. Then the obvious morphism $E \times E \rightarrow G \times G \rightarrow G$ equalizes $f$ and $g$ (use that $f$ and $g$ are group homomorphisms), so we obtain a map $E \times E \rightarrow E$. Similarly one obtains an inverse and a unit, and the group axioms are easy to verify. Moreover, $E \rightarrow G$ is a group homomorphism, so it follows that $E \rightarrow G$ is an equalizer for $f$ and $g$ in $D$.
One goes through the same stuff for (infinite) products, and hence obtains that $F{:}C \rightarrow D$ preserves limits. Apply it to the category of affine $k$-schemes, and you find an affirmative answer to your question.
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Friday, March 7, 2014
Design books have a special place in my heart, because I love to take them out from time to time, pour over all of the great inspiration and learn a few new design tricks. When design books also give the history of a city, culture and way of life, I'm especially inspired. So I was very happy to receive an e-mail from a publishing company rep introducing me to Stealing Magnolias: Tales from a New Orleans Courtyard. The book was written by Debra Shriver and highlights the wonderous city that is New Orleans. The book has a great mix of design with history, exploring the city's rich architecture, food, local customs, music and so much more. I have always been in awe of this city and although I have never visited yet, this book makes you feel as though you are there, experiencing everything New orleans has to offer. Here are some of the amazing highlights and gorgeous imagery from the book...
Could you imagine anything more grand and beautiful! While New Orleans is known for extravagant architecture and design, they also have a laid back, relaxed style that I love. I could just move into the room in the second image! To read more about this book and get your own copy, visit HERE.
I think that I may say that an American has not seen America until he has seen New Orleans.-Mark Twain
Its like you read my mind! You appear to understand so much approximately this, like you wrote the book in it or something. I believe that you simply could do with some percent to power the message house a bit, however instead of that, this is fantastic blog. A great read. I’ll definitely be back.Paints colour ideas NepalCheap paints colors NepalWall Paints NepalLawyers in Love (song)
"Lawyers in Love" is the first single and title track of Jackson Browne's 1983 album of the same name, Lawyers in Love. Though not as successful as Browne's previous single "Somebody's Baby", nonetheless at #13 it became Browne's fourth-highest peaking hit on the Hot 100. Browne wrote most of the songs on the album, including that one.
History
The music video for the "Lawyers in Love" took the title phrase and created a series of visual images surrounding it, especially themed on the Cold War. Browne played at least two or three parts, one
|
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3630
] |
but
you can keep the change.' With that she called an old gentleman up with
a red face, and then Mr. Smith came and took me by the arm, and out we
went."
"And the sixpence?"
"Faith, I've got it still in me pocket."
"How awfully amusing! But look, Mr. Smith has got us a cab. Thanks, no,
I never take gentlemen's arms; it is quite unnecessary."
They took their seats in the taxi, Miss Hitchen and Mr. Dashwood in the
back seat, Mr. Giveen sitting opposite to Miss Hitchen.
"The Albany, Piccadilly end," said Mr. Dashwood to the driver, and they
started.
Before they had well cleared the precincts of the station Miss Hitchen
was alive to the fact that Mr. Giveen was "making eyes at her"--ogling
her. Mr. Dashwood noted the same fact, and with his elbow touched his
companion's arm as if to implore her patience. To have stopped the
taxicab and kicked Mr. Giveen out of it would have been apples of gold
in pictures of silver to Mr. Dashwood, but he controlled himself,
contemplating French's possible salvation as a Buddhist controls himself
by contemplating Nirvana.
At the Piccadilly end of the Albany the taxicab drew up, and Miss
Hitchen, who was on the kerb side, alighted hurriedly. She stood on the
pavement waiting, while Mr. Dashwood paid the driver off, and then the
three entered the Albany. Mr. Dashwood's rooms were situated half-way
up, on the right-hand side, and at the entrance of them he stopped and
turned to Mr. Giveen.
"Will you come in and wait for me a few minutes? Miss Hitchen will
excuse me if I run in for a moment with you to show you the way. You can
sit and wait for me a few minutes while I see Miss Hitchen into a cab.
Come, this is the way."
Mr. Giveen held out his hand to the girl. "It's sorry I am to have seen
so little of you," said Mr. Giveen, "but, sure, if we have any luck, we
may meet again."
"Yes, I suppose so," replied Miss Hitchen, releasing her hand. "Good
evening."
She waited.
In less than a minute and a half Mr. Dashwood reappeared.
"Bobby," said Miss Hitchen, as she turned with him to the Vigo Street
entrance, "I have forgiven you many things, but that Thing is too much
to be forgiven without a very complete explanation. Do you know that it
put its toe on my foot in the cab?"
"Beast!" said Mr. Dashwood. "Can you imagine my fix, tied to it? I feel
as if I were going to burst. Now, look here. Here's my situation in a
nutshell. I know a man called French, the nicest fellow in the world.
He's almost broken; but he has one thing left--a racehorse. The horse is
almost sure to win the City and Suburban, and if he does French will
make a fortune. Well, French is training the horse down at Crowsnest, in
Sussex. French owes a moneylender named Lewis a lot of money, and Lewis
doesn't know where French is. If he knew it, he would send down a man
to-morrow and collar the horse. Do you see?"
"Yes."
"Giveen is French's cousin."
"Poor Mr. French!"
"And he has a mortal hatred to French. He has been hunting for his
address for the last long time, and he has found it. He went down to
Crowsnest to-day to make sure. He strayed into a bazaar that was going
on there, and I met him. He was acting like a cad, refusing to pay for a
cup of tea. Miss Grimshaw, French's governess, pointed him out to me,
and told me who he was, and I froze on to him. I said my name was Smith,
and I told him I hated French, and he unbosomed himself to me. Well,
here's the position now. To-morrow morning he's going down to Lewis, the
moneylender, and is going to put Lewis on to French. Now, you see the
position I'm in. For Heaven's sake, try to think of what's to be done."
"When is the race?" asked Miss Hitchen.
"On the 15th."
"Well, unless you murder him I don't see that anything is to be done. If
the race were to-morrow or next day, you might chloroform him, or lock
him up in your rooms, but you can't lock a man up for ten days."
"He ought to be locked up for life," said Bobby. "Idiot! If I could only
make the beast tipsy, I might do something with him, but he drinks
nothing--only stone gingerbeer."
"Ah!" suddenly said Miss Hitchen, pausing.
"What is it?" asked Mr. Dashwood.
"An idea."
"Yes?"
"Why not sequestrate him?"
"What's that?"
"Hide him away."
"Where on earth could I hide him?"
"Good gracious, Bobby, haven't you any imagination?"
"Not much," replied the unfortunate Bobby. "I was never any good at
working out things, and now I'm so addled I can't think."
"Well, now, listen to me. I don't want to be accessory before the act in
this business, and I only make suggestions. Tell me, do you not
sometimes go duck-shooting?"
"Yes."
"Where do you go?"
"Essex."
"Where in Essex (I know, because you have several times told me, but I
want you to fully answer my question)--where in Essex do you go duck
shooting?"
"Why, you know very well it's Flatmarsh, down near Canvey Island."
"Where do you stay there?"
"Uncle James' hole of a cottage."
"Is Uncle James' hole of a cottage occupied now?"
"No."
"No one lives near it?"
"Not within six miles."
"Good. Can you drive a motor-car?"
"Should think so!"
"And hire one?"
"Yes; I've got tick at Simpson's. Oh, by Jove! I see what you mean!"
"I'm glad you do; otherwise I would have fancied that your mental sight
was defective."
"I see what you mean. But, look here, if I got him down there, how
would I feed the beast and keep him hid?"
"Biscuits and tinned meat can be bought, and enough for a fortnight
wouldn't cost more than, say, three or four pounds."
"And there's a well there, so we'd have plenty of water," said Mr.
Dashwood. "I say, you are a ripper. I'd never have thought of all that."
"Would Simpson, or whoever he is, let you hire a car for a fortnight?"
"'Course he would. I always pay up my bills, though he has to wait
sometimes; but I paid him my last bill a month ago."
"Where is his place?"
"Just close here, in Regent-street."
"Now, another thing--can you imagine what it would be to live for nearly
a fortnight alone in a cottage with a person like that, acting as his
gaoler?"
"Oh, heavens!" said Bobby. "You think everything! No, I can't, but I'll
do it to save French."
"Bobby," said Miss Hitchen.
"Yes?"
"Do you know what I have discovered?"
"No."
"That I'm a fool."
"You a fool?"
"Yes. I thought you were only an irresponsible boy, but I find you're a
man."
"Thanks, thanks," said Bobby. "Anyhow, I'll try to be."
"You needn't thank me. Now, have you any money?"
"About five pounds."
"Well, I'll lend you another five pounds. No, I won't, but I'll buy the
provisions myself. If I left that to you, you'd forget the essentials.
Are there plates and things at the cottage?"
"Lots."
"Well, now, like a good boy, go at once to Simpson's, and order the car,
and get back before that animal takes it into his head to escape."
"Do you mean I ought to take him to-night?"
"Of course I mean it."
"Will I see you again this evening?"
"No, but you can write
|
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] |
specific instances of possible misconduct which Plaintiffs have set forth in their Complaint suffice to meet this burden. Kinnard's failure to inform Plaintiffs of the aforementioned material facts which Kinnard had knowledge of are more than sufficient to withstand a rule 9(b) inquiry.
To satisfy the element of scienter under 10b-5, Plaintiffs must allege facts that "give rise to a strong inference that the defendants possessed the requisite fraudulent intent." Kramer v. Time Warner, Inc., 937 F.2d 767, 775-76 (2d. Cir.1991). In asserting a failure to adequately plead scienter, Defendants rely in part on Center Savings & Loan Ass'n v. Prudential-Bache Securities, Inc., 679 F.Supp. 274 (S.D.N.Y.1987) which they argue is "remarkably similar" to the case at bar. In Center Savings, the court dismissed Plaintiff's securities fraud claims because Plaintiff had failed to demonstrate that Plaintiff knew or acted recklessly with respect to Defendant's financial difficulties. The court held that, at most, Plaintiff had alleged negligence because Plaintiff only argued that Prudential Bache "should have known" of the company's dilemmas in the course of due diligence, but never demonstrated knowledge or reckless disregard. Id. at 277-78.
Contrary to Defendants' allegation, the facts of Center Savings are significantly different from those of the present action. This is not simply a case of failure to properly investigate the financial dealings of a company that a brokerage firm is marketing. Kinnard knew that the housing projects were not being erected. Kinnard knew that investors were concerned about Citi-Equity's projects. Most importantly, Defendants do not refute or address the fact that Kinnard employees worked directly for Citi-Equity. As employees of Citi-Equity, the court finds it difficult to believe that those employees did not know that the company president and sole owner, Gary Lefkowitz, had been found guilty of violations of the California Business and Professions Code and Rules of Professional Conduct. Nor can the court ignore these employees' failure to divulge to Plaintiffs any information regarding the fact that the president and sole owner of Citi-Equity was censured, fined and assessed costs by the NASD in 1988 for violating the Fair Practice Rules, was the subject of a June 17, 1986 Cease and Desist Order for sale of securities without registration and was expelled from the National Association of Securities Dealer on October 3, 1989. Finally, the court cannot accept Kinnard's argument that the Kinnard employees working for Citi-Equity did not know that Citi-Equity failed to obtain permanent financing for their projects when Kinnard represented to Plaintiffs that Citi-Equity had secured $18 million from a company for the permanent financing of the housing projects.
Defendants' characterization of Plaintiffs' allegations as those of mere negligence is wrong; Plaintiffs' allegations successfully establish, at the very least, reckless disregard by Kinnard of a company whose president and sole owner had committed a plethora of securities violations. In re Time Warner Inc. Secs. Litig., 9 F.3d 259, 268-69 (2d Cir. 1993), cert. denied sub nom. As the Court in Center Savings stated, "Whether such declarations be regarded as statements of fact or opinion, their utterance does not state a claim for securities fraud unless the plaintiff also alleges that at the time of the declarations, the views expressed were not honestly held or... were recklessly arrived at." 679 F.Supp. at 276.
As to the causation element, Plaintiffs have adequately demonstrated that "some causal nexus" exists between Kinnard's conduct and Plaintiffs' loss. In re Control Data Corp. Sec. Litig., 933 F.2d 616, 619 (8th Cir.), cert. *446 denied sub nom. The Complaint demonstrates that Plaintiffs relied upon Defendants' representations in purchasing units of FSMI XVI units, thereby satisfying the "transaction causation" element of a 10b-5 claim. Id. Additionally, Plaintiffs have also demonstrated "loss causation" by alleging a sufficient nexus between Kinnard's alleged violations and Plaintiffs' pecuniary losses.
In presuming the validity of the factual allegations set forth in Plaintiffs' Complaint, the allegations are sufficient to adequately plead a cause of action under rule 10(b) of the Securities Exchange Act. Accordingly, the court denies Defendants' Motion to Dismiss under rule 10(b).
B. Section 12(2) Claims
Section 12(2) of the Securities Act of 1933 provides that any person who offers or sells a security by means of a material misstatement or omission in an oral communication or prospectus may be liable to his or her purchaser. 15 U.S.C. § 771(2); Finne v. Dain Bosworth, Inc., 648 F.Supp. 337, 341 (D.Minn.1986). Unlike claims under section 10(b), claims under section 12(2) do not require proof of scienter or reliance. Because Plaintiffs have adequately alleged violations under rule 10(b), these allegations are sufficient to support a cause of action under section 12(2). Accordingly, the court denies Defendants' Motion to Dismiss under section 12(2).
C. Minnesota Securities Act Claims
The Minnesota Securities Act, Minn. Stat. § 80A.01 et seq., is the state's counterpart to federal Rule 10b-5 and the substantive requirements are the same. See, Minneapolis Employees Retirement Fund v. Allison-Williams Co., 519 N.W.2d 176, 180 (Minn.1994). Accordingly, the court denies Defendants' Motion to Dismiss under the Minnesota Securities Act for the reasons stated above.
D. State Law Claims
1. Negligent Misrepresentation
An individual or entity commits the tort of negligent misrepresentation when:
in the course of his business, profession or employment, or in any other transaction in which he has a pecuniary interest, supplies false information for the guidance of others in their business transactions, is subject, to liability for pecuniary loss caused to them by their justifiable reliance upon the information, if he fails to exercise reasonable care or competence in obtaining or communicating the information.
Nordale, Inc. v. Samsco, Inc., 830 F.Supp. 1263, 1270-71 (D.Minn.1993) (quoting Florenzano v. Olson, 387 N.W.2d 168, 174 n. 3 (Minn.1986)). Plaintiff must also establish a pecuniary loss was caused by its justifiable reliance on the alleged misrepresentation. Nordale, at 1271 (citing Conwed Corp. v. Employers Reinsurance Corp., 816 F.Supp. 1360, 1362 n. 3 (D.Minn.1993) (citations omitted)).
Plaintiffs have sufficiently alleged that Kinnard failed to exercise reasonable care in communicating the information regarding the FSMI XVI units to its investors. Additionally, the Complaint also fulfills the other requisite elements of a claim of negligent misrepresentation that, Kinnard entered into this transaction for pecuniary gain, that it supplied false information to Plaintiffs and Plaintiffs detrimentally relied on these alleged misrepresentations. Accordingly, the court denies Defendants' Motion to Dismiss Plaintiffs' claim for negligent misrepresentation.
2. Breach of Fiduciary Duty
Defendants allege that a licensed stockbroker owes his customer only the duty to exercise due care in executing all instructions expressly given to him by the principal. Rude v. Larson, 296 Minn. 518, 207 N.W.2d 709, 711 (1973). For the aforementioned reasons, Plaintiffs' Complaint adequately alleges a breach of that duty. Accordingly, this court denies Defendants' Motion to Dismiss Plaintiffs' claim for breach of fiduciary duty.
3. Class Arguments
Defendants also move to dismiss that part of the Complaint which seeks to assert common law claims on a class basis. This aspect *447 of the motion is premature, as Plaintiffs have not yet moved for class certification. Accordingly, Defendants arguments will be reserved until such time as a motion for class certification is before the court.
ORDER
Accordingly, based upon the above, and all files, records, and proceedings herein, IT IS HEREBY ORDERED that the motions of Defendants for dismissal pursuant to Rules 12(b)(6) and 9(b) of the Federal Rules of Civil Procedure or in the alternative for a more definite statement are DENIED. Defendants' motion to strike allegations pertaining to class certification is RESERVED until such time as Plaintiffs move for class certification.
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Lost in yesterday and tryin hard to work out today.
I am nither here or there.
So i try and put how i feel right here.....
If you get me.....................
its my turn...
Saturday, 12 November 2016
repost?
What ever happens I love you, tho I cant find the words to tell you.
And that's my mistake.
The family pet left to die, i cant help but live a sigh,
Every sliver lining has a cloud,
And i am to needy for love,
To narrow minded for such things
|
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Young
Matured: 8 to 10 weeks
Matured:
16 to 18 weeks
Extra
Matured: 7 to 8 months
Old
or Fully Matured: 10 to 12 months
Very
Old or Very Aged: over 12 months
The younger Gouda cheeses will have a more mild, soft, and almost sweet taste and texture.They’re best on sandwiches or crackers. The older Gouda cheeses acquire more complex notes and layers of flavors, ranging from caramel to pineapple. They also become harder, stronger, and darker. The deep flavor of the older Gouda makes it great for cooking. I have paired an American Gouda with an American parmesan, shrimp and crab meat for this interesting cheesecake.
Ingredients
3/4 cup dry bread
crumbs
1/4 cup grated
Parmesan cheese
1/2 teaspoon chopped
chives
2 tablespoons butter,
melted
CHEESECAKE:
2 tablespoons butter
1 medium sweet red
pepper, finely chopped
1 small onion, finely
chopped
1 medium carrot,
finely chopped
1/2 teaspoon chopped
chives
1/2 teaspoon Creole
seasoning
1/4 teaspoon salt
1/4 teaspoon pepper
3 packages (8 ounces
each) cream cheese, softened
1/2 cup heavy whipping
cream
4 large eggs, lightly
beaten
1 pound peeled and
deveined cooked shrimp, chopped
2 cans (6 ounces each)
lump crabmeat, drained
1 cup shredded Gouda
cheese
SAUCE:
1 cup mayonnaise
2 tablespoons Dijon
mustard
1/2 teaspoon Creole
seasoning
Assorted crackers
Directions
Preheat oven to 350°.
In a small bowl, mix bread crumbs, Parmesan cheese and chives; stir in butter.
Press onto bottom of a greased 9-in. spring form pan. Place pan on a baking
sheet.
For cheesecake, in a
large skillet, heat butter over medium-high heat. Add red pepper, onion and
carrot; cook and stir until tender. Stir in seasonings. Cool slightly.
In a large bowl, beat
cream cheese, cream until smooth. Add eggs; beat on low just until combined.
Fold in vegetable mixture, shrimp, crab and Gouda cheese. Pour over crust.
Bake 60-65 minutes or
until center is almost set. Cool on a wire rack 10 minutes. Loosen sides from
pan with a knife. Cool 1 hour longer. Refrigerate overnight, covering when
completely cooled.
In a small bowl, mix
mayonnaise, mustard and Creole seasoning. Remove rim from spring form pan.
Serve cheesecake with sauce and crackers.
Cover top of
cheesecake with grated parmesan, chopped chives and drizzle with sauce.
Note
The following spices may be substituted for 1 teaspoon Creole
seasoning: 1/4 teaspoon each salt,
garlic powder and paprika; and a pinch each of dried thyme, ground cumin and cayenne pepper.
Like this:
Manchego is a cheese made in the La Mancha region of Spain from the milk of sheep of the manchega breed. Official DOP (Protected Denomination of Origin) manchego cheese is to be aged for between 60 days and two years. Manchego has a firm and compact consistency and a buttery texture, and often contains small, unevenly distributed air pockets.
Characterized by a mildly gamy (think lamb choppy) flavor and a hazelnutty sweetness, Manchego is everywhere. It’s arguably Spain’s most well-known cheese, made in La Mancha with the whole (full-fat) milk of Manchega sheep. Younger versions are aged for about 3 months, but you can find wheels aged for 9 months or longer, at which point they become drier and punchy, with a longer, more resilient finish. You’ll find examples that are bland and innocuous, but when you’ve happened to find a great producer, you’ll taste only round, meaty flavors and a distinct, creamy bite. Another traditional way of aging the cheese is in olive oil, which produces a rindless, super-dense end product.
You’ll see Manchego made with pasteurized or raw milk, it’s hard to judge the cheese solely on whether or not it’s a pasteurized version or raw. It’s easy to spot Manchego from afar because of its rind. It’s inedible and waxy with a cross-hatched, herringbone pattern that it gets after being drained and molded in a patterned basket.
Traditionally, it’s served with membrillo (Quince paste) and marcona almonds, or maybe some Serrano ham. A glass of sherry is an obvious choice to spotlight its nutty notes, or some Crianza Rioja wouldn’t hurt, either. But don’t fear straying from Spanish territory. Manchego, with its fullness and fatty backbone, is a versatile pair for many red wines and fuller bodied whites. Since it’s made with 100% sheep milk, it will be higher in fat, and can actually ooze out its butterfat as it comes to room temperature. This is the reason that a wedge may look shiny or on a cheese plate.
More and more, we’ve been seeing it used in cooking, with suggestions for its incorporation into mac & cheese, sandwiches and NOW Cheesecake. Manchego makes an excellent melter and works wonders with all types of egg dishes.
Here is our family recipe for Cheesecake!
Cheesecake
1 Cup Manchego cheese cut into cubes
2 ounces of water
1 cup cream cheese
½ cup sugar
1 ½ tablespoons flour
2 medium eggs
3 oz sour cream
Graham Cracker Crumb Crust
6 oz butter
½ cup firmly packed brown sugar
1 tablespoon honey
1 cup flour
½ teaspoon salt
½ teaspoon cinnamon
Blackberry Puree
1 cup fresh blackberries
2 tablespoons sugar
1 tablespoon vodka
Instructions Graham Cracker Crumbs
Preheat oven to 350 degrees.
In a stand mixer cream butter, sugar and honey
In a separate bowl mix all dry ingredients.
Add dry ingredients to butter mixture and beat until smooth
Cover bottom of cake rings with crumbs and bake 5 minutes.
Let cool for 5 minutes
Instructions Cheesecake
Preheat oven to 325 degrees
Blend Manchego cheese and water in blender until smooth
In separate bowl blend combine flour and eggs add to cheese
Add sour cream to cheese and blend until smooth
Pour into ring molds and bake for 20 – 25 minutes. Remove and allow to cool.
Like this:
A savory holiday appetizer that is light, airy, creamy and slightly salty with just the right amount of either sweet or tang! These will be the hit of the season. As the wife of a chef and cheese affineur there is no shortage of different cheeses to experiment with. Then when the “snowbirds” hit the Florida town of Vero Beach there is no shortage of test tasters at the local farmers market Saturday mornings. We will be back at the market December 1st.
Just think a strawberry (it is almost time for local Florida strawberries) champagne mojito, the Christmas tree ready for decorations and these tasty little treats for the evening.
Ingredients
1 ¼ cups cracker crumbs
4 tablespoons melted butter
1 egg white
16 ounces cream cheese at room temperature
1 cup shredded parmesan cheese
2 tablespoons chopped fresh basil
1 tablespoon sugar
2 large eggs room temperature
1/8 teaspoon salt
Instructions
Preheat oven to 350 degrees
In a small bowl combine cracker crumbs, butter, egg white until combined.
Press ½ tablespoon of the crumb mixture into each well of a mini cheesecake pan.
Bake crust in oven for 10 minutes. Remove crust from oven and allow to cool for at least 5 minutes.
Like this:
This is not a new flavor combination in fact it has been around for a long time in France. Dark Chocolate and Blue Cheese was made famous by Chef Michel Bras in a dessert called Coulant. We are going to make Roquefort Bites which are Roquefort cheese rolled into balls and then rolled in chocolate pieces. But first some history.
The Legend
A long time ago, every story starts out this way and because this is a French cheese you know it has to include a little romance. So we begin, at the base of the Combalou Mountain, a shepherd spotted a beautiful young woman. He ran after her, leaving behind his flock and his meal, which included ewe’s milk curds, in a cave with some bread. The young woman didn’t want to be caught and so she ran and hid from the shepherd having him chase her for days
|
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3058,
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1379,
629,
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273,
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6493,
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42,
1978,
598,
342,
512,
253,
6323,
13554,
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253,
3745,
281,
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5702,
7535,
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1491,
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897,
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2220,
841,
8130,
15,
187,
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11888,
7269,
4302,
281,
1361,
4822,
2136,
941,
285,
840,
970,
326,
941,
8069,
310,
253,
1682,
1039,
281,
1408,
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5547,
2136,
285,
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253,
6936,
285,
2793,
281,
1691,
436,
5853,
281,
789,
323,
634,
2567,
15,
187,
187,
7845,
1067,
313,
10768,
4587,
39948,
14,
3680,
1976,
281,
873,
598,
247,
1388,
285,
673,
323,
271,
4572,
835,
359,
476,
2319,
253,
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2007,
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187,
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7542,
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13,
187,
187,
34222,
187,
187,
47495,
15967,
17953,
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3546,
498,
27,
2213,
2123,
187,
187,
9395,
634,
1211,
5702,
2819,
21058,
323,
1959,
970,
776,
21058,
22074,
2,
46,
678,
1083,
9727,
3579,
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1302,
187,
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13,
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17324,
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665,
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285,
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11996,
672,
352,
31032,
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187,
187,
23433,
264,
407,
6834,
418,
8885,
18707,
13,
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11418,
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21405,
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417,
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46708,
840,
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13,
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7942,
15,
754,
310,
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2918,
387,
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308,
11550,
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10947,
19804,
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2809,
267,
3348,
4819,
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4472,
254,
13,
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322,
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38,
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2022,
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2905,
9189,
281,
512,
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878,
90,
4292,
273,
776,
5948,
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380,
643,
8103,
275,
9046,
436,
4517,
369,
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3324,
253,
8920,
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275,
2022,
5542,
273,
5674,
323,
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4583,
2440,
273,
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5680,
1375,
15,
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15415,
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271,
11331,
32097,
594,
347,
246,
77,
27,
18,
70,
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7815,
407,
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1805,
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247,
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285,
345,
463,
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10825,
13,
1175,
2285,
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273,
5919,
285,
33842,
4323,
13,
9551,
285,
1327,
9551,
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13,
15986,
3966,
15,
310,
2424,
15,
380,
4096,
273,
8273,
310,
281,
5115,
436,
15,
380,
10215,
1227,
52,
4078,
13698,
34977,
74,
10,
1916,
22435,
4730,
273,
2710,
3510,
285,
4910,
323,
253,
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1805,
420,
273,
253,
4292,
285,
7613,
323,
15519,
273,
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5948,
14517,
2886,
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22435,
3733,
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4730,
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380,
3733,
16,
43052,
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830,
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2710,
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13519,
598,
281,
667,
1268,
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18920,
14,
38079,
13519,
16,
23557,
13519,
16,
24441,
13519,
16,
4775,
8246,
6952,
16,
401,
1939,
4730,
273,
667,
2629,
13,
512,
390,
667,
273,
667,
673,
7467,
9,
12211,
10,
380,
14892,
273,
4775,
285,
2021,
15519,
24040,
14517,
400,
10,
1916,
2085,
9189,
323,
5586,
14,
38079,
3733,
1690,
8710,
4302,
13,
18033,
1974,
13,
22587,
321,
1272,
280,
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String,-5,"") property to trim, but was unsuccessful.
Im new to umbraco. Any help would be highly appreciated.
A:
I'd be interested to know the reason for doing this. Using the Remove method worked for me:
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string url = CurrentPage.Url;
url = url.Remove(url.Length - 5);
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Story TOpics
Former Alaska Gov. and 2008 GOP vice presidential nominee Sarah Palin is among those scheduled to appear at the inaugural Iowa Freedom Summit next month, to be hosted by GOP Rep. Steve King and Citizens United.
A number of past and possibly future GOP presidential hopefuls are scheduled to appear at the event to be held Jan. 24, about a year in advance of the first-in-the-nation Iowa caucuses, including Sen. Ted Cruz of Texas, former Arkansas Gov. Mike Huckabee, retired neurosurgeon Ben Carson, former Sen. Rick Santorum of Pennsylvania, and former House Speaker Newt Gingrich.
The summit is billed as “a launch point for conservative ideas” heading into 2016, and will also give potential candidates a chance to pitch themselves to grassroots party activists who play a significant role in the caucuses every four years.BI Consultant Cover Letter
I am writing in reply to the posting of an opening now available for a BI Consultant with Infosys Technologies Ltd.
With a bachelor’s degree in business and master’s in technology, I have the education needed to fill this position. I have also spent years training and gaining the experience needed to qualify for a position as a Business Intelligence Consultant and I would like to put my expertise to work for your company.
I have included my resume with complete details of my education, work history and skills but here is a brief look at what I can contribute to your company.
I have excellent interpersonal skills with the ability to give clear instructions and the ability to follow specific directions to ensure efficiency. I have the skills to improve business procedures to save time and cut down on expenses and the experience needed to take part in the development of financial projects.
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Please call (111)-863-5875 to set up a day and time for an interview where we can discuss the details further.
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Signature
Randolph Graham
Encl: Resume
Create your own professional looking resume for free using our resume builder!Meth case moves forward in court
June 15, 2012
Preliminary hearings for four of the five people arrested in an alleged methamphetamine manufacturing case within the last two weeks in Elkins were scheduled in Randolph County Magistrate Court Thursday.
The hearings for April D. Kenney, 30, and Jeffery R. Corley, 48, were held simultaneously. According to court documents, police went to the residence they share in Bowden on June 4 and found an active methamphetamine laboratory.
Corley was arrested June 4 and is charged with operating a clandestine laboratory to manufacture methamphetamine. Kenney, who was arrested June 3, is charged with one count of possession of precursor to manufacture methamphetamine.
Article Photos
Studer
Miller
On Thursday, both Corley and Kenney waived their rights to a preliminary hearing, and their cases will go forward to the circuit court. Their attorneys requested that their bonds, which were each set at $50,000 cash only, be modified. Both are being held at the Tygarts Valley Regional Jail.
Attorney Dwight Hall, representing Kenney, said she has family in the area and a brief criminal record. He also noted that she has two infant children. Kenney began sobbing when her children were mentioned.
Attorney Raymond Lamora, representing Corley, said his client has a young child, and has no history of violent crime. Lamora pointed out that no weapons were found at the alleged crime scene.
Prosecuting Attorney Michael Parker said he "strongly opposed" bond modification. "Methamphetamines are a scourge on our society," he said.
Hall said that he felt the state's case is "a holding mechanism" until the federal government "picks it up, if they're interested."
Magistrate George M. Riggleman denied the bond modification requests.
Steven "Pacco" B. Miller, 39, of Harman, was the only one of the four defendants whose preliminary hearing was held Thursday. Miller is charged with operating a clandestine laboratory to manufacture methamphetamine.
During Miller's hearing, Deputy A. Vanscoy of the Randolph County Sheriff's Department testified that when he arrived at the Bowden residence of Kenney and Corley on June 4, Miller had a lithium battery on his person, along with methamphetamine in his back pocket.
Vanscoy said he saw what "appeared to be an operating lab" in an outbuilding on the property, and called the state police.
Trooper D.R. Wolford Jr., a certified clandestine laboratory technician with the Elkins detachment, testified Thursday that when he approached the outbuilding "I could smell a strong odor. It kind of burns."
Wolford said he dismantled an operating meth lab in the building that included "a couple pop bottles." The person or persons operating the lab were using the "shake and bake method," he said.
"There were visible gases coming off both bottles," Wolford said.
Law enforcement officials around the country have warned that the "shake and bake method" is extremely dangerous, because the bottles sometimes explode, causing a flash fire. Several people have reportedly died who were holding a "shake and bake" bottle when it exploded.
Questioned by attorney Lori Gray, representing Miller, Wolford said the lab was not portable.
Gray then said that the charge against Miller should be dropped, because the lab equipment "obviously" belonged to the residents, Kenney and Corley, and not Miller.
Riggleman ruled there was probable cause for the case to move forward to the circuit court. Miller's bond remains at $50,000 cash. He is being held at the Tygarts Valley Regional Jail.
Shalae Brooke Studer, 21, of 1860 Beverly Pike, Elkins, was granted a continuance Thursday. Her preliminary hearing will be at a later date.
Studer is charged with one count of possession of precursor to manufacture methamphetamine. Her attorney, Jim Hawkins, asked that her bond be lowered from $50,000 cash only to $25,000 cash, property or surety.
Hawkins pointed out that Studer has no prior felonies on her record. He noted that the fifth defendant in the case, Brian Keith Hammer, 58, of 1120 S. Henry Ave., Elkins, has "the same charge" but has a lower bond, set at $25,000.Important information
Course programme
B. Sc. Nursing (Post basic)
The Year 2003 was the year when this Trust /Society by the name of AMBIKA PRASAD PANDEY EDUCATION & RESEACH FOUNDATION MOHALI was formed. The main objective in forming this society was to provide health education and health related facilities to all the needy individuals of our society. The other objective in forming this trust was to bring the youth of Punjab in main stream of nation for the overall development of this border state. For the better functioning of an educational institute so as tl:1e produce good citizens by providing them better education in a healthy and congeinal atmosphere, good team work of efficient and sincere management, teaching and non teaching staff, volunteers etc. is required. The purpose of Society is to achieve this. The Trust /Society aims :(i) To impart education of various types and fields for the overall betterment of the individuals and hence for welfare of the society.(ii) To impart training / education to the needy. The training/education in the form of various medical courses up to any level/para-medical courses/ Technical courses/Law courses/ Health Programmes/ Formal education of any standard, all or any of any time duration(iii) The promotion of Health and family welfare programmes.(iv) To provide facilities for para-medical training including Medical technology, Pharmacy, Ayurvedic, Homoeopathy, Nursing, Health education and Health workers etcThe Trust / Society will endeavour :(a) To Establish Institutions, Schools, Colleges And Training Centres, Laboratories, Research Centres and Health clinics to Impart Education for the purposes reffered to above(b) To organise camps for various family welfare programmes, to provide various Health Services and medical Check-ups for various sections of the Society(c) To Establish MCH and immunisation Projects and Post Partum Centres(d) To Conduct intelligence / Pre-admission tests and to grant scholarship and stipends to the deserving candidates(e) To Print, publish and distribute literature, books, magazines, and newspapers to propagate the purposes for which the society stands for(g) To work for betterment of Medical Profession and promote the interests of individuals involved in medical service and education.(h) To Establish holiday camps for
|
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a la MLS. El Athletic le había hecho una oferta para continuar pero, según desveló el pasado marzo elconfidencial.com, el futbolista la desestimó. Aunque nadie del club ha dado conformidad a la información, el futbolista ha comenzado a despedirse de sus allegados.
El vestuario conoce el adiós y Valverde hacer esfuerzos por no darle publicidad al asunto. "Andoni no ha hecho nada público y yo tampoco he hablado con él de eso. Cada uno es dueño de sus decisiones. Es una persona inteligente y como no ha dicho nada no tengo que anticiparme a nada", explicó.
Iraola firmará dos temporadas por su nuevo club. Viajará con su esposa y su hija y es posible que igual que ocurrió con David Villa haga un rodaje previo en Australia para no perder la forma y llegar en las mejores condiciones posibles a su nuevo destino.The Mauritian Economy Defied Predictions Of James Meade Economics Essay
Few Sub-saharan African states have managed to accomplish high criterions of life over the past two decennaries. Mauritius has been a noteworthy exclusion. With no natural resources, a little domestic market and exposure to external dazes, Mauritius exhibited a series of features really typical to the remainder of Africa viz. a mono-crop economic system, exposure to footings of trade dazes, high population growing rate, cultural tensenesss exacerbated by high income and wealth inequality.
Defying the anticipations of Nobel Prize receiver James Meade, who famously predicted hapless development chances for Mauritius back in 1961 due to its exposures to both conditions and monetary value dazes and deficiency of occupation chances outside the sugar sector, Mauritius has transformed itself from a hapless sugar economic system into a state with one of the highest per capita incomes among African states.
Today, the little island state is one of Africa ‘s most comfortable and stable economic systems and is considered an economic success narrative. For statement ‘s interest, between 1977 and 2009, existent GDP in Mauritius grew on norm by 5.1 per centum yearly, compared with 3.2 per centum for sub-Saharan Africa.
3.1 The Mauritanian Economy
Mauritius is a little island developing province with limited resources and a distant geographical location considered unfavorable. Since its independency in 1968, Mauritius has developed from a low-income glandular fever harvest economic system to a middle-income comparatively diversified export-oriented economic system.
In the early 1960 ‘s, Mauritius embarked on a plan of variegation and adopted import permutation policies with the initial accent on revenue enhancement freedoms, long-run loans at favourable rates and protective import responsibilities and quotas. The purpose was chiefly to battle unemployment, raise criterion of life and alleviate poorness.
However, import permutation did non convey the benefits expected owing to the little size of the domestic market, limited resource gifts and proficient know-how. The endeavors were unable to profit from economic systems of graduated table given the little size of the local market. Furthermore, import permutation policies failed to turn to unemployment, which reached 20 % in the late 60 ‘s.
In the early 1970 ‘s, Mauritius switched to an outward-looking export-oriented scheme. The constitution of the Export Processing Zone strategy, designed to promote the puting up of labors intensive export oriented fabrication endeavors, aimed at assisting to stifle the turning job of unemployment, every bit good as to open up farther the economic system and benefit from the discriminatory entree to the European markets under the different Lome Conventions ( and now the Cotonou Agreement ). The governments prudent direction of the economic system and their outward-oriented policies placed Mauritius on a sustained growing way. Launched with the start-up capital of the sugar sector, the EPZ sector has concentrated largely on fabric and textile-related merchandises. Mauritius seeks to function as a span from Asia to Africa, Europe and the United States: in the 1980s, companies from Taiwan, Hong Kong, and Singapore settled in the state ‘s economic processing zones ( EPZs ), and were joined in 2007 and 2008 by companies from mainland China. For the past three decennaries, the industry have attracted FDI from assorted states, created new employment chances and strengthened the fabricating base of the economic system.
The touristry sector besides emerged as a serious economic pillar by lending to foreign exchange net incomes of the state and by being an of import generator of employment. A scope of investing inducements were provided to hike the development of the touristry sector in footings of financial inducements and fiscal support for hotel development and direction services. The labor-intensive export-oriented growing scheme was hence powered by three chief economic sectors, viz. sugar, fabric merchandises and touristry.
The variegation scheme was farther expanded in the 1990s with the consolidation of the fiscal services sector into commercial banking, insurance and planetary concern. In recent old ages, information and communicating engineering ( ICT ), in peculiar concern procedure outsourcing, and the seafood hub have emerged as of import sectors of the economic system. From 1991 to 2010, the economic system enjoyed an mean one-year existent growing of 4.9 %. To farther diversify the economic base of the island, the authorities is actively encouraging development in the undermentioned sectors:
Mauritius is a reasonably good diversified export oriented economic system with agribusiness, fabric, touristry and fiscal services as prima sectors. However, a gradual displacement from agribusiness to the service sectors has been observed. Today, the services sector makes the largest part towards GDP and towards entire employment. The portion of the agricultural, hunting, forestry and fishing sector in GDP which was 6.1 % in 1999 went down to 4.3 % in 2009. The fabrication sector besides experienced a autumn, from 23.9 % in 1999 to 19.5 % in 2009. On the other manus, “ Hotels and eating houses ”, a major constituent of the Tourism sector, witnessed a rise from 6.9 % to 7.3 % during the same period.
Albeit the successful growing records, there is turning concerns as respects fight and sustainability of growing. The traditional Mauritanian labour-intensive exports is being challenged by new rivals. Productivity is non increasing fast plenty to maintain gait with rewards that have been lifting as a consequence of near full employment, therefore gnawing fight. Government policies are taking at diversifying towards more capital-intensive production and higher value added goods.
The acceleration of the growing rate in the 1980s is the consequence of the macroeconomic reforms in response to drawn-out balance of payments and financial problems. Following the reforms, Mauritius experienced steady growing, low rising prices, and increased employment. GDP per capita, meanwhile, increased about septuple between 1976 and 2008, from less than $ 1,000 to about $ 7,000 ( figure 2 ). At the same clip, consumer monetary value rising prices in Mauritius has remained in the low individual figures through the 1990s and 2000s ( figure 3 ).
The steady growing way of the early old ages of the period under reappraisal was due to the sugar roar of the early 1970 ‘s and the freshly established EPZ pulling foreign investing. During that period, GDP grew at an norm of 9 % per twelvemonth. However, the roar was short lived with sugar monetary values falling by 50 % and the first oil daze of 1973-74 get downing to impact on stray Mauritanian exporters and the little but promising touristry industry. Year 1979 saw the devaluation of the exchange rate by 30 %, a rise in involvement rate, decrease in nutrient subsidies and pay additions held below rising prices. Between 1979 and March 1980, the island was hit by cyclones, sugar production tumbled and GDP fell by 9 %. The lone encouraging factor during that period was a autumn in rising prices.
The highest rate of rising prices Mauritius witnessed since its independency was in October 1980 at 42 %. This was due to the deteriorating economic state of affairs following increasing oil monetary values in the late seventiess coupled with inauspicious conditions conditions damaging nutrient harvests. In the same period, the island adopted its first Structural Adjustment Programme and the rupee was devalued by 22.9 % in October 1979. The direct impact of the devaluation was seen on import monetary values which sky rocketed.
Macroeconomic policies have contributed to incorporating rising prices. On a calendar-year footing, rising prices ( measured by alterations in consumer monetary values ) was maintained at under 6.5 % per twelvemonth boulder clay 2006, when it rose to 8.9 %. The chief subscribers to this addition include higher oil monetary values ( ensuing from addition in universe monetary values and the debut of the Automatic Pricing Mechanism, higher monetary values of alcoholic drinks and coffin nails ( ensuing from the addition in excise responsibilities ) and of some other merchandises ( ensuing from the decrease of subsidies for rice, flour, and staff of life ), addition in cargo costs and depreciation of the Mauritanian rupee. During 2007, rising prices increased farther to make 10.7 % in June ( on a annual footing ), the highest in over a decennary. Harmonizing to the BOM, this was due to the second-round effects of high oil and trade good monetary values, the depreciation of the Rupee, and the addition in
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] |
then, she won both county and state photography
competitions, including ‘Best of the Best’ Illinois State Awards. www.mbakerphotography.com
stephanie lindenmuth Hailing from East Lansing, Michigan, Stephanie is an experienced
entrepreneur who has a personal emphasis on sales and marketing. She is structuring distribution
relationships for The Printed Blog as well as helping to organize our internal operations.
kylie MUGG is a 20 year-old student from Orange County, California. She currently resides in Chicago
where she is working to earn her degree in public relations from DePaul University. In addition to her
interest in communications, Kylie is also interested in environmental studies.
Lauren Davis is a community manager at TPB. She attends DePaul University, and has a strong
passion for both the written word and the art of communication.Thursday, July 13, 2017
Forbid face time for fake news
Destroying the media enemy requires a cold hard look at how they operate, what their source of power is, and what our power is that can counteract that. This will downplay the importance of launching another meme war against CNN (or MSNBC or whoever), and instead shift the focus toward the need to break up the monopolies that control the media.
If it can be done then by all means do so.
A less herculean task, and one that would prove more popular in the nearer-term, is for Trump and his team to simply bar them from press conferences--including Sean Spicer's daily briefings--and grant members of select organizations no more access than the White House allows private citizens visiting the capital as tourists. Make it administration policy not to grant interviews or otherwise talk to anyone from any of those on the figurative proscription list.
If you're part of a fake news outlet, you get no access, period. If you misrepresent yourself in an attempt to get information, you'll be subject to prosecution for fraud, trespassing, etc. If you get in an official's face in public, you'll be charged with assault.
Media figures are not high priests. They're the middle men of information conveyance in a world that increasingly has no need for middle men conveying information. Communications now come from the whole seller directly to the consumer.
The utter collapse in confidence in the major media--both print and television--is staggering. The following graphs show the percentages of people who answered that they have "a great deal of confidence" and "hardly any confidence at all" in each media platform, by year. The third possible response, "only some confidence", is not shown, but is the difference between 100 and the other two percentages shown in any given year:
We are to a point now where a majority of Americans have "hardly any confidence at all" in the press, and most of the balance are themselves wary. Sentiment towards TV isn't far behind.
The latest year we have data for is 2016. Response gathering was scattered throughout that year. Some respondents were answering prior to the Iowa caucuses occurring. Rest assured the figures will be markedly worse still when the 2018 iteration of the survey is released.
Shutting out fake news organizations won't create any significant blow back. Nobody watches these cable news shows. The few who do are geriatric white leftists. The average CNN viewer is in his sixties and getting older by the day. The #resistance that rallies to the defense of the hated and distrusted media will comprise a small contingent of the Coalition of the Fringes, a contingent the rest of the coalition is most eager to push out anyway.
Even the thoroughly converged corporate world is moving away. There are several podcasts I've listened to for years that have recently begun taking on ads that are indistinguishable from the ones that run during NFL games. The advertising used to only be for niche goods and services. Now there are ads for cars on The Art of Manliness and The History of Byzantium.
Trump should grab some easy populism points by helping send the fake news organizations to their graves.GSS variables used: CONTV(1)(3), CONPRESS(1)(3), YEAR
27 comments:
andrewknorr
said...
Looks like the turning point was Clinton's first term, though beginning with Clarence Thomas hearigns in 1991 and peaking around the time of contract with America in 1994. Basically when the boomers (Clinton and Gingrich) took over. There doesn't seem to be any obvious event that kicked it off, though I guess looking back Bill Clinton did really represent something entirely new.
My ideal scenario for Trump:1) Defund the humanities and social sciences while outright banning some subjects under title vi and title ix (all the ethnic studies/gender studies/critical theory studies subjects) under the basis they promote hatred of whites and men. Title ix is used like this by the left all the time, it's about time we start using it against the left.2) Open up the libel laws so that the media can't knowingly spread fake news. Trust bust the major media corporations.3) Trust bust the other major corporations that continually donate to leftist causes.4) Enact a Soros law preventing him and his money from influencing american politics.
While I despise the Lügenpresse as much as you do, any sort of official government action against them is unwise and probably unconstitutional - and it would make them appear to be martyrs and victims. If Trump wants to exclude them from his news conferences and briefings, that's his call. However, government takng action against media because it disapproves of what they are saying smacks of police state or banana republic. You can be sure, if the Democrats ever get back in control, they will be delighted to use such a weapon against outlets such as Fox or Drudge or Breitbart or even the WSJ.
We all know what frauds, hypocrites and villains these sanctimonious MSM types are - they're not fooling anyone. Best to let them twist slowly in the wind. Freedom of speech means freedom for the speech we hate, as I am constantly reminding Leftists. Let them go on peddling their lies - I'll stick with the First Amendment.
The last poll I saw showed that the MSM and politicians were running neck and neck as to who is the most untrustworthy occupations. Isn't that great? Two of the most powerful groups are the two least trusted. I hope this trend accelerates.
What about the collapse of the Soviet Union and subsequent revelations of the BS in some media places that the USSR was great? Overblown? I'm much too young to have any personal recollection so I may be way off on this.
Chris,
All good.
Black Death,
This isn't a call to forcibly muzzle the media, it's simply to stop giving them special treatment. I wouldn't even recommend threatening libel. Treat them the same way protesters are treated.
Agree. There was a recent presser with Hope Hicks. She began by saying that she is not taking questions on Don Jr and those questions are referred to his lawyer. Then basically every question was about Don Jr, one after the other, at least a dozen, while she declined every one. What is the point? They are nothing but shrieking protesters.
Nobody thought the SU was great and nobody cares about foreign policy unless there are lots of casualties. I would guess it began long before the numbers started to turn, so probably began at least as far back as Iran-Contra, Clarence Thomas, the Bush-Rather interview, the government shutdown in 1990 that was blamed on Republicans, and then the Clinton win. That was the beginning of the budget standoffs that were always blamed on Republicans.
"What about the collapse of the Soviet Union and subsequent revelations of the BS in some media places that the USSR was great? Overblown? I'm much too young to have any personal recollection so I may be way off on this."
An NY times reporter (or at least regular contributor) whose name escapes me habitually lied about the post-Revolution ruling class and it's atrocities. I'd say that the MSM, after WW1 and during the build-up of the clash between the Allies and the fascists that was WW2, was well on it's way to downplaying Left-wing excess while denigrating ethnic nationalism.
By the 1970's, the nature of commie horrors could no longer be hidden, and very few Westerners openly or even secretly admired any of the commie nations, The Soviets included. Silents and Boomers grew to absolutely detest the "hard controls" of big authoritarian government in any form, whether fascist or communist. However, these privileged generations also shied away from conflicts/ideologies based on economic issues; in the 1970's, both the right and left began to emphasize cultural/moral issues. This created the schism that dominated right along with these generations; the right was religious, pro-life, pro-gun, anti-sex in media, etc. while the Left was secular,feminist, anti-violence in media, etc. Both sides knew about, but didn't care, the growing level of inequality in the post-1970 West. A generation of spoiled ingrates on the right could whine about the church no longer being respected (maybe that's cuz your generation corrupted the church?), while the equivalent Left whined about their children being desensitized to violence (while excusing drug, crime, and abortion epidemics created by Leftist ideology). What united the me-generation was a fear that a "strong-man
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] |
11:08 AM
What is 655 minutes after 2:32 PM?
1:27 AM
How many minutes are there between 6:31 PM and 4:04 AM?
573
What is 627 minutes before 3:43 PM?
5:16 AM
How many minutes are there between 9:30 AM and 10:14 AM?
44
How many minutes are there between 3:49 PM and 5:32 PM?
103
How many minutes are there between 2:29 PM and 2:02 AM?
693
What is 27 minutes before 7:19 PM?
6:52 PM
How many minutes are there between 12:43 PM and 12:01 AM?
678
What is 459 minutes after 9:50 AM?
5:29 PM
What is 681 minutes before 12:09 AM?
12:48 PM
How many minutes are there between 2:09 AM and 1:26 PM?
677
What is 345 minutes after 1:42 PM?
7:27 PM
How many minutes are there between 5:20 AM and 4:29 PM?
669
How many minutes are there between 10:54 AM and 10:36 PM?
702
How many minutes are there between 7:45 PM and 10:06 PM?
141
What is 137 minutes before 8:43 AM?
6:26 AM
How many minutes are there between 9:03 PM and 5:11 AM?
488
How many minutes are there between 9:17 PM and 9:36 PM?
19
How many minutes are there between 2:18 AM and 2:30 AM?
12
What is 202 minutes after 7:57 AM?
11:19 AM
How many minutes are there between 6:14 AM and 3:32 PM?
558
How many minutes are there between 11:47 AM and 5:31 PM?
344
What is 665 minutes before 5:33 AM?
6:28 PM
How many minutes are there between 9:42 AM and 2:33 PM?
291
How many minutes are there between 5:27 AM and 12:35 PM?
428
How many minutes are there between 3:46 PM and 5:43 PM?
117
How many minutes are there between 11:06 PM and 9:03 AM?
597
What is 305 minutes before 5:42 PM?
12:37 PM
How many minutes are there between 7:35 PM and 8:51 PM?
76
How many minutes are there between 1:27 PM and 9:43 PM?
496
What is 657 minutes before 6:43 AM?
7:46 PM
How many minutes are there between 5:10 PM and 2:08 AM?
538
What is 448 minutes before 6:33 PM?
11:05 AM
What is 470 minutes after 12:50 AM?
8:40 AM
How many minutes are there between 8:34 AM and 8:11 PM?
697
How many minutes are there between 12:16 AM and 12:56 AM?
40
What is 52 minutes after 8:18 AM?
9:10 AM
What is 279 minutes after 1:18 AM?
5:57 AM
What is 90 minutes before 4:16 PM?
2:46 PM
What is 643 minutes before 4:02 PM?
5:19 AM
How many minutes are there between 7:26 PM and 2:49 AM?
443
How many minutes are there between 4:38 AM and 11:47 AM?
429
How many minutes are there between 10:59 AM and 3:33 PM?
274
What is 463 minutes before 9:09 AM?
1:26 AM
What is 270 minutes before 10:37 AM?
6:07 AM
How many minutes are there between 8:38 AM and 8:24 PM?
706
How many minutes are there between 8:27 AM and 4:03 PM?
456
What is 315 minutes after 10:39 AM?
3:54 PM
How many minutes are there between 7:25 AM and 3:48 PM?
503
What is 584 minutes before 10:46 AM?
1:02 AM
What is 419 minutes before 7:43 PM?
12:44 PM
How many minutes are there between 5:10 AM and 12:43 PM?
453
What is 231 minutes before 3:50 PM?
11:59 AM
How many minutes are there between 6:35 AM and 5:57 PM?
682
How many minutes are there between 2:43 AM and 1:35 PM?
652
What is 313 minutes before 12:33 PM?
7:20 AM
How many minutes are there between 1:16 PM and 11:59 PM?
643
How many minutes are there between 7:59 PM and 9:15 PM?
76
How many minutes are there between 10:11 AM and 7:06 PM?
535
What is 181 minutes before 9:20 PM?
6:19 PM
What is 504 minutes after 6:17 PM?
2:41 AM
How many minutes are there between 5:32 AM and 9:45 AM?
253
How many minutes are there between 7:36 PM and 10:50 PM?
194
What is 202 minutes before 3:29 AM?
12:07 AM
What is 456 minutes after 1:37 PM?
9:13 PM
What is 552 minutes after 7:22 PM?
4:34 AM
What is 323 minutes before 6:59 AM?
1:36 AM
How many minutes are there between 10:51 AM and 11:24 AM?
33
How many minutes are there between 8:16 AM and 1:16 PM?
300
What is 203 minutes before 2:16 PM?
10:53 AM
How many minutes are there between 11:24 PM and 4:01 AM?
277
What is 439 minutes before 1:35 AM?
6:16 PM
What is 665 minutes after 6:51 AM?
5:56 PM
How many minutes are there between 11:31 PM and 6:29 AM?
418
How many minutes are there between 5:52 PM and 11:59 PM?
367
How many minutes are there between 11:31 AM and 1:39 PM?
128
What is 647 minutes before 10:01 AM?
11:14 PM
What is 416 minutes before 2:23 PM?
7:27 AM
How many minutes are there between 2:53 AM and 1:56 PM?
663
How many minutes are there between 9:23 PM and 5:15 AM?
472
How many minutes are there between 6:50 PM and 7:57 PM?
67
What is 172 minutes after 3:32 AM?
6:24 AM
How many minutes are there between 10:16 PM and 6:27 AM?
491
What is 186 minutes before 7:39 PM?
4:33 PM
How many minutes are there between 6:24 PM and 12:58 AM?
394
What is 564 minutes after 10:59 PM?
8:23 AM
What is 634 minutes after 8:53 PM?
7:27 AM
How many minutes are there between 2:09 AM and 7:32 AM?
323
How many minutes are there between 10:47 PM and 11:43 PM?
56
What is 446 minutes after 5:16 PM?
12:42 AM
What is 584 minutes before 2:09 AM?
4:25 PM
How many minutes are there between 12:19 AM and 11:20 AM?
661
What is 376 minutes after 11:59 AM?
6:15 PM
How many minutes are there between 12:13 AM and 1:15 AM?
62
What is 12 minutes after 3:57 PM?
4:09 PM
How many minutes are there between 1:04 AM and 11:16 AM?
612
What is 687 minutes after 3:05 AM?
2:32 PM
What is 501 minutes after 10:31 AM?
6:52 PM
What is 560 minutes after 3:39 PM?
12:59 AM
How many minutes are there between 11:49 PM and 3:04 AM?
195
How many minutes are there between 5:01 AM and 11:27 AM?
386
What is 418 minutes after 8:32 AM?
3:30 PM
What is 141 minutes before 2:34 PM?
12:13 PM
What is 128 minutes before 3:50 AM?
1:42 AM
What is 238 minutes before 5:26 AM?
1:28 AM
How many minutes are there between 7:02 AM and 9:42 AM?
160
How many minutes are there between 4:38 AM and 2:22 PM?
584
How many minutes are there between 4:52 PM and 4:25 AM?
693
How many minutes are there between 12:47 PM and 7:18 PM?
391
How many minutes are there between 6:24 AM and 2:03 PM?
459
How many minutes are there between 12:39 PM and 1:46 PM?
67
What is 91 minutes after 11:22 PM?
12:53 AM
What is 59 minutes after 12:39 PM?
1:38 PM
What is 665 minutes before 9:04 PM?
9:59 AM
What is 44 minutes after 10:02 AM?
10:46 AM
What is 507 minutes before 6:40
|
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] |
Exh. A, Supplemental Affidavit of James C. Crozier ¶ 6 (TNT Holland frequently tops off interstate loads). And at oral argument, ATA conceded the absence of record facts that empirically could show that the $100 fee significantly deters interstate trade. Tr. of Oral Arg. 5.
Neither does the record show that the flat assessment unfairly discriminates against interstate truckers. The fee seeks to defray costs such as those of regulating "vehicular size and weight," of administering "insurance requirements," and of applying "safety standards." App. to Pet. for Cert. 44a. The bulk of such costs would seem more likely to vary per truck or per carrier than to vary per mile traveled. See *436 255 Mich. App., at 612-617, 662 N. W. 2d, at 799-801. And that fact means that a per-truck, rather than a per-mile, assessment is likely fair. Cf. Jefferson Lines, 514 U. S., at 199 (rejecting taxpayer's discrimination claim in part because "miles traveled within the State simply are not a relevant proxy for the benefit conferred upon the parties to a sales transaction"). Nothing in the record suggests the contrary.
Nor would an effort to switch the manner of fee assessment from lump sum to, for example, miles traveled be burden free. The record contains an affidavit, sworn by a Michigan Public Service Commission official, that states that to obtain the same revenue (about $3.5 million) through a per-mile fee would require the State to create a "data accumulation system" capable of separating out intrastate hauls and determining their length, and to develop related liability, billing, and auditing mechanisms. App. 64, Second Supplemental Affidavit of Thomas R. Lonergan ¶ 2. This affidavit, on its face, suggests that the game is unlikely to be worth the candle. While petitioners argue the contrary, they do not provide the details of their preferred alternative administrative system nor point to record evidence showing its practicality. See Jefferson Lines, supra, at 195 (State is not required to use a particular apportionment formula just because it may be "possible" to do so).
Petitioners insist that they do not need empirically to demonstrate the existence of a burdensome or discriminatory impact upon interstate trucking, or (presumably) the unfairness of the assessment in relation to defrayed costs, or (presumably) the administrative practicality of the alternatives. They say that our earlier case, American Trucking Assns., Inc. v. Scheiner, 483 U. S. 266 (1987), requires invalidation of the $100 flat fee, even in the absence of such proof. We disagree.
In Scheiner, this Court invalidated a flat $25 "marker fee" and a flat "axle tax" that Pennsylvania levied upon all trucks (interstate and intrastate) that used its roads, including *437 trucks that merely crossed Pennsylvania's borders to transport, say, Ohio goods to New Jersey customers. See id., at 273-275. Data showed that the fees imposed a cost per mile on interstate trucks that was approximately "five times as heavy as the cost per mile borne by local trucks." Id., at 286. The assessments largely helped to raise revenue "to improve and maintain [the State's] highways and bridges," id., at 270, thereby helping to cover costs likely to vary significantly with truck-miles traveled, see ibid. And the assessments did "not even purport to approximate fairly the cost or value of the use of Pennsylvania's roads." Id., at 290. In light of these considerations, Pennsylvania's lump-sum taxes "threaten[ed] the free movement of commerce by placing a financial barrier around the State of Pennsylvania." Id., at 284. We concluded that "[i]f each State imposed flat taxes for the privilege of making commercial entrances into its territory, there [was] no conceivable doubt that commerce among the States would be deterred." Ibid.
The present fee, as we have said, taxes purely local activity; it does not tax an interstate truck's entry into the State nor does it tax transactions spanning multiple States. See 255 Mich. App., at 592-594, 662 N. W. 2d, at 789. We lack convincing evidence showing that the tax deters, or for that matter discriminates against, interstate activities. See supra, at 434-435. Nor is the tax one that, on its face, would seem to call for an assessment measured per mile rather than per truck. See supra, at 435-436. Consequently, we lack any reason to infer that Michigan's lump-sum levy erects, as in Scheiner, an impermissible discriminatory roadblock.
Petitioners add that Michigan's fee fails the "internal consistency" test a test that we have typically used where taxation of interstate transactions is at issue. Generally speaking, that test asks, "What would happen if all States did the same?" See, e. g., Goldberg v. Sweet, 488 U. S. 252, 261 (1989); Jefferson Lines, supra, at 185 (test looks to the *438 structure of the tax to see whether its identical application by every State "would place interstate commerce at a disadvantage as compared with commerce intrastate"). We must concede that here, as petitioners argue, if all States did the same, an interstate truck would have to pay fees totaling several hundred dollars, or even several thousand dollars, were it to "top off" its business by carrying local loads in many (or even all) other States. But it would have to do so only because it engages in local business in all those States. An interstate firm with local outlets normally expects to pay local fees that are uniformly assessed upon all those who engage in local business, interstate and domestic firms alike. See, e. g., Commonwealth Edison, 453 U. S., at 623-624 (dormant Commerce Clause does not seek "to relieve those engaged in interstate commerce from their just share of state tax burden even though it increases the cost of doing business" (internal quotation marks omitted)); cf. Jefferson Lines, supra, at 187-188 (in context of sales tax, "the Commerce Clause does not forbid the actual assessment of a succession of taxes by different States on distinct events as the same tangible object flows along"). A motor carrier is not special in this respect.
In sum, petitioners have failed to show that Michigan's fee, which does not seek to tax a share of interstate transactions, which focuses upon local activity, and which is assessed evenhandedly, either burdens or discriminates against interstate commerce, or violates the Commerce Clause in any other relevant way. See Complete Auto Transit, Inc. v. Brady, 430 U. S. 274, 279 (1977) (noting that a tax will be sustained where it is applied to an activity with a "substantial nexus" to the taxing State; where, if applied to interstate activity, it is "fairly apportioned"; where it does not discriminate; and where it is "fairly related to the services provided").
For these reasons, the judgment of the Michigan Court of Appeals is affirmed.
It is so ordered.
*439 JUSTICE SCALIA, concurring in the judgment.
Michigan imposes a flat fee on trucks that engage in purely intrastate commercial operations. I agree with the Court that this fee does not violate the negative Commerce Clause. Unlike the Court, ante, at 433, 437-438, I reach that determination without adverting to various tests from our wardrobe of ever-changing negative Commerce Clause fashions: the balancing approach from Pike v. Bruce Church, Inc., 397 U. S. 137 (1970), the four-factor test from Complete Auto Transit, Inc. v. Brady, 430 U. S. 274 (1977), and the internal-consistency test from cases such as American Trucking Assns., Inc. v. Scheiner, 483 U. S. 266 (1987). Instead, I ask whether the fee "facially discriminates against interstate commerce" and whether it is "indistinguishable from a type of law previously held unconstitutional by this Court." West Lynn Creamery, Inc. v. Healy, 512 U. S. 186, 210 (1994) (SCALIA, J., concurring in judgment). As the Court correctly concludes, Michigan's fee meets neither of those conditions. It does not facially discriminate against interstate commerce, ante, at 434, and it is distinguishable from petitioners' best analogue, the fees invalidated in Scheiner, which applied to interstate trucks even when they engaged in no intrastate business, ante, at 436-437.
JUSTICE THOMAS, concurring in the judgment.
I would affirm the judgment of the Michigan Court of Appeals because "`[t]he negative Commerce Clause has no basis in the text of the Constitution, makes little sense, and has proved virtually unworkable in application,' Camps Newfound/Owatonna, Inc. v. Town of Harrison, 520 U. S. 564, 610 (1997) (THOMAS, J., dissenting), and, consequently, cannot serve as a basis for striking down a state statute." Hillside Dairy Inc. v. Lyons, 539 U. S. 59, 68 (2003) (THOMAS, J., concurring in part and dissenting in part).
NOTES
[*] Briefs of amici curiae urging reversal were filed for the Chamber of Commerce of the United States of America by Christopher J. Wright and Robin S. Conrad; for Deeco Services, Inc., dba Deeco Transportation, et al. by Robert E. McFarland; and for the Eagle Forum Education & Legal Defense Fund by Douglas G. Smith.
Briefs of amici curiae urging affirmance
|
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346,
22176,
301,
13,
5516,
301,
13,
5159,
779,
13,
5159,
779,
1476,
187,
187,
22176,
301,
23238,
253,
24011,
3000,
13,
285,
344,
340,
7042,
13,
346,
7878,
13,
1790,
598,
13,
1007,
387,
479,
275,
253,
5130,
1476,
285,
4754,
13,
253,
2448,
3249,
598,
13,
533,
344,
556,
1633,
275,
521,
1133,
534,
45151,
84,
2584,
5516,
301,
13,
285,
840,
521,
13386,
310,
13195,
13,
285,
344,
14177,
281,
42963,
1633,
969,
13,
533,
521,
6208,
310,
2120,
273,
2614,
285,
344,
11521,
896,
15,
187,
187,
42,
452,
642,
3835,
594,
309,
1353,
2509,
752,
434,
1925,
26441,
762,
3289,
13,
285,
309,
1158,
309,
755,
253,
5654,
1342,
342,
253,
749,
28936,
5654,
285,
840,
18797,
333,
80,
310,
327,
253,
3216,
13,
14954,
896,
387,
479,
13,
533,
10902,
13,
751,
954,
23332,
13,
344,
434,
417,
908,
281,
14954,
275,
247,
21291,
1899,
13,
285,
627,
434,
37031,
1981,
33737,
347,
16334,
40257,
407,
479,
13,
285,
309,
5310,
285,
5310,
285,
309,
1353,
26400,
387,
253,
37342,
251,
434,
20052,
13,
285,
840,
387,
18797,
333,
80,
13,
323,
619,
7636,
4394,
403,
275,
326,
4958,
285,
309,
1353,
417,
670,
281,
1339,
352,
1481,
562,
15,
187,
187,
510,
10581,
15828,
3369,
8423,
42206,
1527,
13,
285,
6270,
285,
7682,
885,
3034,
934,
562,
275,
247,
13477,
19176,
13,
285,
309,
1978,
327,
26441,
13,
285,
1529,
37342,
251,
687,
1032,
407,
13,
2914,
15828,
3369,
5909,
598,
13,
285,
18797,
333,
80,
6613,
281,
352,
13,
285,
309,
1053,
626,
1557,
13,
309,
1339,
779,
564,
15,
6270,
285,
7682,
885,
403,
987,
1060,
13,
285,
18797,
333,
80,
476,
564,
281,
253,
3729,
45724,
323,
512,
309,
1557,
13,
285,
1024,
309,
1379,
3835,
3212,
253,
806,
37342,
251,
285,
6270,
21968,
689,
13,
2927,
4618,
13,
6107,
342,
2614,
13,
285,
344,
434,
15586,
281,
1379,
247,
5313,
273,
11173,
745,
521,
6208,
15,
187,
187,
1898,
253,
1652,
3226,
1735,
281,
779,
310,
275,
7615,
2806,
1499,
7305,
285,
271,
444,
5902,
302,
17052,
23565,
13,
285,
347,
309,
3986,
323,
617,
13,
6270,
39783,
13,
346,
2773,
434,
417,
7682,
885,
2,
2064,
434,
417,
7682,
885,
1476,
187,
187,
510,
3226,
21968,
689,
13,
2927,
4618,
13,
11173,
327,
617,
6208,
347,
973,
15,
187,
187,
34,
24627,
8230,
12830,
479,
594,
1892,
309,
1158,
309,
1849,
644,
10903,
407,
271,
38068,
3790,
15,
187,
187,
510,
3226,
310,
417,
7682,
885,
15,
187,
187,
42,
1408,
281,
253,
2914,
273,
253,
13603,
37342,
251,
15,
187,
187,
510,
1273,
37342,
251,
310,
1335,
627,
13,
3369,
1527,
13,
18797,
333,
80,
21266,
715,
253,
15828,
434,
7319,
13,
285,
627,
434,
247,
21643,
660,
45110,
13,
285,
840,
344,
439,
11625,
562,
247,
1652,
3226,
665,
39783,
13,
346,
24681,
2577,
1476,
285,
840,
703,
434,
7320,
896,
275,
285,
253,
3369,
1499,
1317,
285,
253,
37342,
251,
687,
1032,
745,
15,
187,
19658,
9330,
187,
187,
53,
2277,
27196,
48685,
5626,
17954,
598,
285,
18967,
265,
387,
253,
2614,
327,
521,
2454,
285,
14133,
15,
3032,
2406,
9246,
403,
1335,
14049,
407,
11173,
15,
754,
18684,
5200,
896,
715,
253,
10581,
19867,
7319,
273,
253,
37342,
251,
13,
9010,
253,
9968,
4968,
13,
4566,
896,
562,
281,
253,
12102,
2257,
13,
2987,
387,
521,
9246,
15,
187,
187,
2512,
434,
247,
637,
13889,
275,
253,
2914,
7319,
13,
305,
3922,
1981,
285,
22626,
272,
13,
285,
6270,
2506,
626,
971,
281,
320,
2822,
779,
15,
187,
187,
2512,
15,
187,
187,
510,
11173,
310,
745,
285,
6270,
2987,
281,
1959,
253,
1652,
3226,
15,
1500,
434,
270,
1403,
1981,
13,
285,
344,
556,
642,
2934,
665,
703,
310,
1128,
23955,
21064,
522,
5487,
32,
1128,
395,
2378,
617,
11173,
310,
745,
13,
703,
4850,
598,
285,
6613,
1977,
13,
22233,
15,
187,
187,
15883,
11403,
247,
637,
327,
253,
3216,
13,
9246,
285,
6174,
256,
35293,
562,
13,
285,
344,
7362,
1369,
868,
689,
285,
11403,
253,
637,
434,
2927,
403,
1527,
13,
285,
521,
6208,
310,
7808,
5909,
285,
11196,
13,
751,
247,
6773,
562,
273,
1824,
13,
7808,
6237,
406,
839,
15,
3032,
3168,
7619,
14133,
310,
38149,
342,
2614,
13,
344,
556,
8244,
36756,
3168,
4707,
285,
29970,
13,
285,
9506,
3622,
13,
344,
369,
6306,
1735,
281,
521,
4475,
13,
22138,
15,
187,
187,
3,
20405,
13,
309,
1353,
6270,
44677,
937,
344,
3678,
793,
562,
15,
346,
42,
1353,
1051,
34681,
13,
309,
1353,
594,
7016,
436,
4592,
15,
309,
24156,
281,
2656,
449,
187,
187,
15883,
458,
507,
689,
347,
253,
637,
23727,
16544,
15,
346,
42,
1353,
7016,
13,
1512,
13,
326,
309,
476,
626,
3662,
634,
3533,
13,
353,
2131,
44677,
1051,
2858,
1051,
42,
1158,
368,
1537,
452,
2217,
323,
247,
1984,
13,
25685,
865,
187,
187,
510,
637,
27599,
521,
2927,
15,
187,
187,
34,
637,
273,
521,
4907,
9309,
265,
310,
6276,
253,
1273,
37342,
251,
13,
285,
253,
22233,
1652,
3226,
310,
275,
18797,
333,
80,
434,
13427,
13,
285,
344,
7819,
281,
253,
10581,
285,
2296,
13,
346,
3220,
3392,
13,
858,
368,
923,
619,
3392,
865,
187,
187,
24226,
468,
310,
627,
13,
25288,
275,
521,
987,
1133,
15,
346,
795,
20723,
453,
8291,
309,
3047,
779,
2965,
15,
309,
3047,
2614,
327,
521,
9081,
449,
187,
187,
510,
3226,
310,
1335,
22233,
13,
285,
18797,
333,
80,
1499,
1825,
521,
1133,
689,
253,
1308,
255,
434,
6208,
15,
187,
187,
3,
8620,
937,
344,
2296,
13,
347,
253,
3226,
3896,
11178,
285,
23490,
327,
521,
13427,
15,
187,
187,
24226,
468,
23071,
2296,
13,
346,
8620,
32,
1198,
1524,
13,
795,
5173,
453,
64,
865,
187,
187,
49,
293,
333,
80,
340,
7042,
281,
9309,
265,
13,
346,
39780,
7938,
13,
11213,
1476,
187,
187,
510,
2872,
637,
1863,
19085,
253,
37342,
251,
1475,
247,
1387,
273,
2151,
13,
6306,
275,
253,
4766,
273,
253,
12102,
2257,
13,
285,
18819,
281,
253,
7394,
15,
187,
187,
42,
1849,
35611,
253,
19456,
19153,
14,
1258,
2695,
285,
309,
1353,
16893,
2439,
253,
3511,
347,
45302,
273,
253,
12102,
2257,
13,
840,
253,
10583,
13,
840,
253,
12102,
2257,
969,
13,
619,
32530,
322,
17146,
275,
619,
987,
1133,
13,
3515,
13,
3515,
13,
3515,
13,
417,
13872,
253,
37342,
251,
755,
562,
273,
619,
8184,
15,
187,
187,
510,
2806,
4958,
8423,
14545,
275,
2914,
273,
247,
1387,
273,
17053,
2151,
13,
1863,
19085,
13,
285,
840,
21460,
598,
3885,
15,
187,
187,
31484,
15,
187,
187,
31484,
15,
187,
187,
8836,
403,
7487,
285,
13458,
387,
253,
20540,
90,
3416,
653,
3867,
562,
273,
617,
11332,
90,
14,
24290,
270,
1479,
5391,
13,
3515,
13,
5877,
247,
25288,
275,
617,
3564,
13,
285,
309,
11823,
731,
512,
15,
187,
187,
510,
37342,
251,
310,
13590,
987,
2584,
253,
7394,
15,
187,
187,
31484,
15,
187,
187,
18837,
309,
3523,
13,
4388,
323,
253,
26429,
32,
187,
187,
5804,
309,
513,
326,
32,
187,
187,
1989,
436,
310,
642,
44741,
4460,
13,
642,
8230,
48530,
358,
14,
484,
6440,
13,
642,
5440,
921,
327,
5579,
13,
835,
253,
8080,
476,
320,
247,
4289,
11433,
1977,
285,
9257,
5310,
562,
253,
10581,
26429,
273,
247,
16893,
4958,
15,
309,
1353,
16060,
13,
309,
1353,
11790,
13,
285,
604,
309,
1462,
285,
1611,
281,
5310,
13,
10739,
13,
309,
1537,
1379,
562,
247,
20052,
13,
247,
15307,
408,
429,
13,
390,
1128,
187,
187,
34,
1029,
14,
15507,
3790,
432,
619,
1133,
13,
619,
10485,
13,
812,
2740,
949,
253,
10581,
3497,
273,
253,
37342,
251,
285,
5159,
619,
1652,
3226,
15,
187,
187,
42,
1053,
626,
3523,
15,
187,
187,
42,
1978,
327,
3515,
15,
187,
187,
12978,
11853,
1067,
253,
3513,
846,
6523,
436,
5310,
483,
32,
7395,
253,
36248,
9549,
281,
253,
14471,
32,
187,
187,
4527,
2282,
417,
15,
187,
187,
1552,
13345,
3114,
3562,
407,
2854,
2583,
556,
642,
3513,
15,
187,
187,
31484,
15,
187,
187,
510,
37342,
251,
2789,
247,
1614,
281,
253,
987,
285,
309,
2740,
987,
347,
973,
13,
285,
309,
48675,
348,
347,
619,
987,
3174,
310,
25530,
5485,
407,
1633,
533,
309,
1053,
626,
1557,
15,
187,
187,
4125,
15,
187,
187,
510,
37342,
251,
556,
6331,
15,
187,
187,
10971,
2,
187,
187,
34,
1133,
32361,
432,
253,
1669,
1930,
13,
2987,
247,
2234,
11022,
15,
187,
187,
31484,
15,
187,
187,
34,
40532,
7866,
331,
22590,
1892,
387,
619,
1669,
1930,
15,
187,
187,
510,
25288,
9193,
751,
352,
40581,
247,
7020,
15,
187,
187,
3220,
14578,
310,
17770,
285,
49109,
15,
187,
187,
3,
20990,
885,
1476,
309,
12452,
15,
187,
187,
510,
7394,
6386,
7866,
31494,
1981,
281,
253,
987,
15,
187,
187,
510,
15307,
408,
4380,
273,
253,
37342,
251,
25924,
347,
253,
6254,
3936,
521,
3174,
745,
253,
36609,
15,
187,
187,
688,
247,
1643,
7253,
253,
36175,
342,
619,
41802,
6122,
22995,
588,
16092,
564,
562,
715,
7137,
285,
840,
15529,
15,
187,
187,
3,
20990,
885,
1476,
187,
187,
42,
3324,
598,
619,
25288,
533,
352,
9193,
19437,
15,
187,
187,
42,
1353,
1512,
2080,
1977,
15,
187,
187,
42,
1353,
417,
1469,
281,
1056,
352,
15,
187,
187,
3,
20990,
885,
1476,
309,
12452,
581,
625,
673,
15,
187,
187,
4013,
13,
2656,
13,
309,
1353,
417,
1469,
281,
1056,
352,
15,
187,
19658,
11614,
187,
187,
7538,
1372,
40,
1410,
11324,
19212,
521,
4430,
275,
285,
253,
7394,
7866,
4886,
13,
285,
18797,
333,
80,
310,
13224,
352,
588,
512,
789,
562,
15,
496,
816,
247,
1643,
2909,
13,
344,
1833,
320,
387,
247,
3055,
50239,
7417,
281,
253,
29510,
273,
13140,
2189,
13,
285,
342,
12000,
468,
285,
436,
1652,
3226,
342,
779,
13,
597,
1833,
1481,
896,
6420,
281,
8987,
15,
187,
187,
2512,
344,
1833,
294,
4399,
285,
1158,
1841,
949,
15,
187,
187,
510,
1652,
3226,
310,
1335,
17800,
285,
15586,
15,
187,
187,
1909,
323,
617,
32,
187,
187,
4497,
13,
344,
6057,
326,
5113,
476,
320,
2197,
3066,
6742,
2718,
281,
4829,
9825,
275,
253,
1986,
2077,
15,
329,
1355,
15076,
8781,
342,
13831,
6079,
6749,
651,
1978,
1633,
5352,
323,
2067,
1897,
13,
1919,
352,
1694,
281,
247,
2176,
8663,
13595,
434,
1728,
15,
187,
187,
42805,
13,
751,
247,
1652,
3226,
434,
1481,
15,
187,
187,
510,
7394,
310,
1527,
13,
533,
253,
1039,
310,
13230,
407,
247,
11792,
5542,
273,
24359,
285,
11600,
2184,
398,
13,
285,
12000,
468,
38440,
2296,
13,
346,
510,
44677,
3416,
310,
896,
627,
13,
3515,
387,
441,
449,
187,
187,
3,
35848,
265,
1476,
18797,
333,
80,
340,
7042,
15,
346,
19815,
1476,
187,
187,
510,
6254,
4070,
661,
253,
17081,
13,
253,
1386,
273,
952,
9727,
281,
253,
1669,
285,
987,
13,
3707,
323,
581,
11870,
14,
13565,
13,
2159,
14,
37128,
3416,
13,
8785,
247,
20618,
11600,
33265,
689,
617,
9215,
15,
187,
187,
510,
3416,
2506,
626,
2118,
15,
187,
187,
24226,
468,
2296,
13,
346,
2993,
434,
3551,
8003,
449,
187,
187,
49,
293,
333,
80,
458,
507,
689,
13,
32804,
253,
17081,
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49
] |
ayo screams inside, and he opens fire, just as Paco aims at the woman, and there's an ugly noise of metal being ripped apart, and then there's a quick "oh" and the side of his face is suddenly soaked, and he spares just the quickest of glances, seeing the pockmarked metal on the Yukon's hood where the woman opened fire in Paco's direction.
It looks like four or five rounds worked their way up the metal, until the last bullet took off the top of Paco's head.
Pelayo fires off two rounds, ducks, and picks up the MP5, rolls to the left, and the woman is advancing, shooting at him, and Pelayo yells out, "Hamid, Hamid, kill him, kill him!"
Hamid hears the blessed words, and he yells, "American, sit up, look at me in the eye!" and yes, the American comes up, but he has something in his hand which whirls toward Hamid, and then his throat is burning, and he tries to yell something again, but his mouth is full of blood and he falls back.
I have no cover so I'm doing what's called advancing under fire, and I think I get the gunman with the submachine gun and then Pelayo is on the ground, firing back at me, but yeah, like most civilians, he's not used to firing in a prone position, and there's whistling noises as rounds roar by me, and I shoot and shoot and I'm aiming at the Yukon's tire, and then at Pelayo, for my loved ones are in that vehicle and I'm not about to let it head out.
The rear passenger door suddenly pops open, and Tom and Denise tumble out in a confused pile, and I keep on advancing, and another Yukon roars by, front passenger door opening up, and Pelayo runs to it, and I don't care, I let him go. Tom and Denise are right here, and Pelayo can go to the North Pole for all I care, and now I take cover behind the first Yukon and Tom rolls over, eyes wide, covered with blood, and he's struggling to take a piece of tape off his mouth.
And the little girl next to him is in familiar black slacks and an Epcot sweatshirt, and as I reach for her, Tom screams, "That's not Denise! That's not Denise!"
The girl rolls over, eyes wide, tape on her mouth as well.
A hammer blow hits me so hard I think I've been struck by an RPG round.
The girl is not Denise.
I run to the front of the disabled Yukon.
The second Yukon is still there, door open, Pelayo climbing into the passenger's seat, and there's a confusing scramble, and then he shoves out a little girl who screams, "Mommy!" and then she's pulled back in and the door slams and the Yukon roars off.
CHAPTER 85
TOM CORNWALL sits up and wipes at the blood on his face and shirt. His lower legs are still secured by tape. He crawls back into the rear bloody seat of the Yukon, finds the cutting tool, goes back out to the parking lot, works at his legs.
There's a man dying in the front seat, gurgling and coughing, and Tom doesn't want to be near him.
There.
The tape is off and Tom works to free the little girl. She's bawling, and he has no idea who she is—another kidnap victim?—and once her tape is off, she gets up and runs away, screaming.
Tom sees a man on the ground, legs and arms splayed out, and he scrambles over and sees the man's eyes are open, and his mouth is slowly opening and closing, like a fish out of water, slowly suffocating. His white dress shirt is soaked with blood, he has closely trimmed white hair and beard, and moments ago, he was standing next to his wife, Amy.
"Sir, I'm Tom Cornwall," he gasps out. "I'm...damn, I'm so sorry this happened. I swear to God."
Tom leans over as the man softly speaks. "I'm sorry, too, that I can't answer your questions, Mister Cornwall...but...I think you might have enough for a book, eh?"
The man closes his eyes.
A man of his named Georges is driving the second Yukon, and the screaming little girl is in Pelayo's lap, and he turns to the rear and says, "My father, did you see my father?"
Casper is there, pistol in his right hand. " _Jefe,_ I saw him fall. I saw blood on his chest."
The girl is still screaming, and Pelayo slaps his hand over the brat's mouth.
"Good," he says, as the girl squirms and struggles on his lap.
Casper sharply says, "Good? For real, _jefe_?"
Pelayo yells to Georges, "Drive faster, fool!"
The young man swerves the Yukon around a group of children, standing in the middle of the parking lot, and speeds to the gate.
I've dumped the silly flip-flops and I'm racing across the hot asphalt of the parking lot, then the grass, then the parking lot again, my SIG Sauer in my right hand, running, running, running, not letting the Yukon get out of my sight.
The black vehicle suddenly stops in front of a group of laughing children, swerves, and then picks up speed.
Running.
Running.
People are watching and pointing at the chunky woman spilling out of her teeny-tiny bikini, running, holding a pistol in her hands, and I ignore them all.
The Yukon is heading right toward the gate.
Running.
Should I stop, aim for the tires?
Can I do that?
But this is no thriller novel, no blow-'em-up movie, no cop show on TV, where the hero can be a hundred yards away and carefully shoot out the rear tires of a racing vehicle. I'm scared, I'm angry, and if I stand and try to shoot, shit, I might take out a tire, a taillight, or—
A high-speed round from my hand, my weapon, could break through the rear window of the Yukon and kill my little girl.
I don't stop.
I keep on running.
Will somebody call the police after seeing this shootout? Will the cavalry ride to the rescue?
Of course not.
This artificial community created by drug money has no police.
Running.
The Yukon makes a turn to the right and I break right as well, and I screech as my right foot is sliced opened by something but I don't care.
Now.
The Yukon has stopped.
Finally!
A hand emerges from the left side, works a keypad.
Running.
A stitch starts stabbing hard at my left side.
The pistol feels like it weighs a ton.
My breathing is harsh and ragged.
"Denise!" I scream.
The gate ahead starts rattling to the right.
The taillights of the Yukon blink as the driver takes his foot off the brakes.
In a few seconds the SUV with my kidnapped daughter aboard will quietly go out into traffic and then disappear.
"Denise!"
I bring up my pistol but it feels useless.
I'm too far away.
I'm not going to make it.
"Denise!" I scream one more time.
Oh, God, I'm not going to make it.
CHAPTER 86
GEORGES BRINGS his arm in and the gate starts moving, and Pelayo is confident it will all work out. In just a few minutes, he'll be at a private airstrip to the northeast of Beachside, and with Casper and this little girl with him, they'll head back south to Mexico.
There he'll regroup and think things through.
The little girl is still crying and struggling.
As for her?
Well, he knows that objects can be sent via delivery systems to nearly anywhere in the United States. A small shipping container with frozen dry ice would keep something fresh for several days, until it got to a certain Army captain's home.
Fresh, like a little girl's head.
The gate is open, but the way is blocked by a steady stream of tourists and beachgoers, and Casper calmly says, "The Cornwall woman is back there, running at us."
"Georges!" Pelayo yells. "Move!"
The driver honks the horn, the line of people moves to the left and right, except for one tired-looking, short-haired woman, carrying a folded beach umbrella over her shoulder.
The woman doesn't move.
Casper says, "She's coming closer."
Pelayo leans over, pushes the horn again.
The woman stares and stares at them, and then looks behind the SUV, and back to them.
P
|
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] |
I necked three cans of Red Bull. What's making it worse is that the word had a nasty effect the first time I read it in one of Zodiac's messages, like the name itself tapped into something that made me uneasy, but I can't place why.
With that thought I dry my hands and go to my bedroom, where I open my laptop and search for Synergis on Wikipedia. It's a long entry and I'm aware I've left the chip pan on the heat with Lilly in the kitchen. I could bring my laptop into the room but for various reasons I'm still reluctant to let her know I have it, in case she says anything to anyone (mainly Mum).
I scan the page impatiently, skimming through the early stuff that's talking about 'ambulatory monitoring' and the inventor Jack mentioned, Aldous Syne. I had never heard of him and I don't know what ambulatory monitoring is either. Further down it talks about the company's decline into manufacturing low-end electronics, like generic mobile handsets, knock-off mini hi-fis and crappy clock radios. I must have seen the name on a device somewhere: maybe inside Graythorne Young Offenders Institution, where I spent the worst three days of my life. If so I don't remember, but then I've worked damn hard at blocking those seventy-two hours from my memory.
I scroll down again and read how Synergis changed hands a few times. It was most recently bought over by one of its original founders, Leo Cruz, but again the name means nothing to me.
I hear a knock at the door and I tense up, remembering the last time anyone came calling unannounced. When Lush and his gangsta-bots fronted up before, at least Lilly wasn't home. I'm not opening my door to those bastards with her in the house.
I sneak a look out of the bedroom window, which gives me a view along the outside landing. There is a smartly dressed woman standing in front of the door, holding a briefcase.
I suddenly remember. She's from the Social. She is due here for the home inspection to make sure Lilly's being looked after all right. It's not a surprise visit to catch me unawares, though it's done that anyway. I knew it was today, but I completely forgot, with everything else that's on my mind.
I open the door and she greets me with the thinnest, coldest smile I've ever seen. I never thought it was possible to turn up the corners of your mouth without giving some hint of friendliness and warmth, but she's proved otherwise.
'You must be Samantha. Mary Hardwick,' she says, holding out her ID. 'I hope I haven't caught you at a bad time. You were expecting me, yes?'
'Oh, yes. Sure.'
I smile, instinctively going into please-the-teacher mode.
'Just getting the tea organised,' I add, hoping it scores some points.
'I see.'
She starts nosing around the place while asking me questions.
'You're at sixth form college?'
'Yeah, well, I was. Had to give it up so I can earn some money. I'm starting a job at a sandwich place up in Ilford.'
'Didn't you have any plans for further education?'
This sounds like I'm being told off.
_Well, yeah, course I did, but that's gone south since you lot cancelled my Carer's Allowance, I don't say._
She gives the living room a thorough examination, like she's thinking of buying the place.
'No TV,' she says, her tone so weirdly neutral I can't pick up anything from it.
'That's right. Lilly likes to read comics. Reading's better than TV for a child's development.'
Even as this is spilling from my mouth I am asking myself what the hell I think I'm trying to achieve. I don't know. It just came out from my nervousness.
She glances at the pile of DVDs under the table where it's so laughably obvious that the telly used to sit. She knows I saw her looking at this, and now she's got to be wondering why I barfed up that word-sick.
'Well, Lilly does have a little laptop she uses as a portable DVD player,' I add.
'And where is Lilly?'
'She's in the kitchen.'
With the open chip pan on. Jesus.
I lead her through, trying not to rush.
Lilly looks up from her colouring.
'Hello, Lilly. I'm Mary,' she says.
Lilly gathers her colouring and her pens and scarpers off to her bedroom. She's a sharp judge of character, that girl.
'She's shy,' I say.
Mary doesn't reply.
'What's for dinner?'
It sounds like small-talk but I've no idea how much might hinge on my answer.
'I'm making some chips.'
'With what?'
I swallow.
'Just chips, tonight. Lilly likes chips,' I add.
She says nothing and continues to look the place up and down, wrinkling her nose. She doesn't like what she's seeing, I could tell that much without any talent for reading micro-gestures.
I think of my mum asking me to promise I wouldn't let Lilly get taken into care. I made that promise, but now I'm getting this horrible vision of things being taken out of my hands. I can see how easily the process might start, how quickly it might snowball.
That's when it comes back.
I remember now why that name must have taken root in my subconscious, associated with a fear of losing everything.
A few years back, only months after Dad died, Mum found a lump on one of her breasts. She went for tests, and then she had to go into hospital to have the cancer removed.
I remember her telling us we hadn't to let anybody know we were on our own at home, fending for ourselves while she got her treatment. She said the Social might come and take us away if they found out there was nobody taking care of us, especially with Lilly having special needs.
I had looked after Lilly alone when Mum was at work, but not overnight, and not several nights on the spin. Lilly was a frightened teary mess, restless and confused, but I was the one who was truly afraid, because I was the one who truly understood. If Mum had cancer, if she was going to become ill and then die, it would all be out of our hands. We wouldn't be able to keep our situation a secret. I would lose Mum like I had lost Dad, then I would lose Lilly. We'd both end up God knows where, with God knows who.
I recall the hospital visits most vividly. We only went in a few times, but it stayed with me, and you don't remember the hanging around the house part, because that's normal. Mum was hardly ever lying in a bed when we went in. She didn't like looking helpless, so she was usually on her feet, but she always had this thing attached to her: wires leading from her chest to a little plastic box on her hip. It was called a Synapse Ambulatory Monitor. SAM, like me. She even had it on for a while after she came home. It wasn't even to do with the cancer. They made her wear it because she had developed an irregular heart rhythm and they wanted to keep an eye on it.
It didn't seem to bother her, but the sight of it always troubled me, maybe because I could never see the cancer but I could always see _it._
I can see it now, that beige plastic box, the manufacturer's name prominent on the front.
Synergis.
# REMOTE ACCESS TROJAN
Parlabane watches his destination rise into view as he comes down Monument Street. He feels a horrible burden of inevitable fate settle upon him, like a condemned man approaching Tyburn on the back of a cart and the gallows looming before him. This will be the instrument of his destruction, and yet he is compelled to proceed towards his undoing.
He had hoped the Synergis HQ would be located in some suburban science campus of eighties-built low-rises with corresponding levels of security. Then when he clocked the address, he had nonetheless comforted himself with the possibility that it might be some carbuncle-era concrete slab, unloved and neglected as it awaited the wrecking ball that would follow a sell-off and development of the site. Instead he is looking at Tricorn House: a handsome seven-storey structure that has been sneering down on the likes of him for at least two centuries, a prestigious address where the immaculate maintenance of the stonework outside speaks forebodingly of how well-equipped it is likely to be inside.
He has on occasion thought of his more vainglorious or ill-advised ventures as tilting at windmills, but there seems nothing chivalrous and quixotic about this doomed undertaking. Don Quixote never had Sancho Panza blackmailing him to saddle up and heft the lance. Nor did he have the bastard gibbering in his earpiece the whole time.
'Are you there yet?'
|
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] |
regarding copyright ownership. The ASF licenses this file
* to you under the Apache License, Version 2.0 (the
* "License"); you may not use this file except in compliance
* with the License. You may obtain a copy of the License at
*
* http://www.apache.org/licenses/LICENSE-2.0
*
* Unless required by applicable law or agreed to in writing,
* software distributed under the License is distributed on an
* "AS IS" BASIS, WITHOUT WARRANTIES OR CONDITIONS OF ANY
* KIND, either express or implied. See the License for the
* specific language governing permissions and limitations
* under the License.
*/
package org.netbeans.modules.j2ee.weblogic9;
import java.util.HashMap;
import java.util.Map;
import java.util.concurrent.Callable;
import javax.management.MBeanServerConnection;
import javax.management.ObjectName;
import javax.management.remote.JMXConnector;
import javax.management.remote.JMXConnectorFactory;
import javax.management.remote.JMXServiceURL;
import org.netbeans.modules.j2ee.deployment.plugins.api.InstanceProperties;
import org.netbeans.modules.j2ee.weblogic9.deploy.WLDeploymentManager;
import org.netbeans.modules.j2ee.weblogic9.optional.NonProxyHostsHelper;
import org.netbeans.modules.weblogic.common.api.WebLogicConfiguration;
import org.netbeans.modules.weblogic.common.spi.WebLogicTrustHandler;
import org.openide.util.Lookup;
/**
*
* @author Petr Hejl
*/
public final class WLConnectionSupport {
private final WLDeploymentManager deploymentManager;
// full weblogic code is setting this, causing CNFE on DWP
private static final String PORTABLE_OBJECT_PROPERTY = "javax.rmi.CORBA.PortableRemoteObjectClass"; // NOI18N
// we should hide this constructor
public WLConnectionSupport(WLDeploymentManager deploymentManager) {
this.deploymentManager = deploymentManager;
}
public <T> T executeAction(Callable<T> action) throws Exception {
synchronized (this) {
ClassLoader originalLoader = Thread.currentThread().getContextClassLoader();
String portable = System.getProperty(PORTABLE_OBJECT_PROPERTY);
String originalNonProxyHosts = System.getProperty(NonProxyHostsHelper.HTTP_NON_PROXY_HOSTS);
String configuredNonProxyHosts = NonProxyHostsHelper.getNonProxyHosts();
boolean nonProxyHostsChanged = false;
if (!configuredNonProxyHosts.isEmpty()) {
String nonProxyHosts;
if (originalNonProxyHosts!= null) {
nonProxyHosts = NonProxyHostsHelper.compactNonProxyHosts(
originalNonProxyHosts + "," + configuredNonProxyHosts); // NOI18N
} else {
nonProxyHosts = configuredNonProxyHosts;
}
if (!nonProxyHosts.equals(originalNonProxyHosts)) {
nonProxyHostsChanged = true;
System.setProperty(NonProxyHostsHelper.HTTP_NON_PROXY_HOSTS, nonProxyHosts);
}
}
if (deploymentManager.getCommonConfiguration().isSecured()) {
WebLogicTrustHandler handler = Lookup.getDefault().lookup(WebLogicTrustHandler.class);
if (handler!= null) {
for (Map.Entry<String, String> e : handler.getTrustProperties(deploymentManager.getCommonConfiguration()).entrySet()) {
System.setProperty(e.getKey(), e.getValue());
}
}
}
Thread.currentThread().setContextClassLoader(
WLDeploymentFactory.getInstance().getClassLoader(deploymentManager));
try {
return action.call();
} finally {
Thread.currentThread().setContextClassLoader(originalLoader);
// this is not really safe considering other threads, but it is the best we can do
if (nonProxyHostsChanged) {
if (originalNonProxyHosts == null) {
System.clearProperty(NonProxyHostsHelper.HTTP_NON_PROXY_HOSTS);
} else {
System.setProperty(NonProxyHostsHelper.HTTP_NON_PROXY_HOSTS, originalNonProxyHosts);
}
}
// this is not really safe considering other threads, but it is the best we can do
if (portable == null) {
System.clearProperty(PORTABLE_OBJECT_PROPERTY);
} else {
System.setProperty(PORTABLE_OBJECT_PROPERTY, portable);
}
}
}
}
public <T> T executeAction(final JMXAction<T> action) throws Exception {
InstanceProperties instanceProperties = deploymentManager.getInstanceProperties();
String host = instanceProperties.getProperty(WLPluginProperties.HOST_ATTR);
String port = instanceProperties.getProperty(WLPluginProperties.PORT_ATTR);
if ((host == null || host.trim().length() == 0
&& (port == null || port.trim().length() == 0))) {
if (!deploymentManager.isRemote()) {
// getDomainConfiguration instantiate DocumentBuilderFactory
// if we would add it inside call such factory could be loaded
// from weblogic classes causing troubles, see #189483
WebLogicConfiguration config = deploymentManager.getCommonConfiguration();
host = config.getHost();
port = Integer.toString(config.getPort());
}
if ((host == null || host.trim().length() == 0
&& (port == null || port.trim().length() == 0))) {
String[] parts = deploymentManager.getUri().split(":"); // NOI18N
host = parts[3].substring(2);
port = parts[4]!= null? parts[4].trim() : parts[4];
}
}
final String resolvedHost = host.trim();
final String resolvedPort = port.trim();
return executeAction(new Callable<T>() {
@Override
public T call() throws Exception {
boolean secured = deploymentManager.getCommonConfiguration().isSecured();
JMXServiceURL url = new JMXServiceURL(secured? "t3s" : "t3", resolvedHost, // NOI18N
Integer.parseInt(resolvedPort), action.getPath());
String username = deploymentManager.getInstanceProperties().getProperty(
InstanceProperties.USERNAME_ATTR);
String password = deploymentManager.getInstanceProperties().getProperty(
InstanceProperties.PASSWORD_ATTR);
Map<String, Object> env = new HashMap<String, Object>();
env.put(JMXConnectorFactory.PROTOCOL_PROVIDER_PACKAGES,
"weblogic.management.remote"); // NOI18N
env.put(javax.naming.Context.SECURITY_PRINCIPAL, username);
env.put(javax.naming.Context.SECURITY_CREDENTIALS, password);
env.put("jmx.remote.credentials", // NOI18N
new String[] {username, password});
JMXConnector jmxConnector = JMXConnectorFactory.newJMXConnector(url, env);
jmxConnector.connect();
try {
return action.call(jmxConnector.getMBeanServerConnection());
} finally {
jmxConnector.close();
}
}
});
}
public static interface JMXAction<T> {
T call(MBeanServerConnection connection) throws Exception;
String getPath();
}
public static abstract class JMXRuntimeAction<T> implements JMXAction<T> {
public abstract T call(MBeanServerConnection connection, ObjectName service) throws Exception;
@Override
public final T call(MBeanServerConnection connection) throws Exception {
ObjectName service = new ObjectName("com.bea:Name=DomainRuntimeService," // NOI18N
+ "Type=weblogic.management.mbeanservers.domainruntime.DomainRuntimeServiceMBean"); // NOI18N
return call(connection, service);
}
@Override
public final String getPath() {
return "/jndi/weblogic.management.mbeanservers.domainruntime"; // NOI18N
}
}
|
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] |
padding: 0;
display: flex;
max-width: 600px;
}
#input1 {
background: red;
transition: all.5s ease;
}
#input2 {
background: blue;
transition: all.5s ease;
}
#input1:focus {
flex: 1 1 auto;
}
#input2:focus {
flex: 1 1 auto;
}
<form id="testForm">
<input type="text" id="input1">
<input type="text" id="input2">
</form>
A:
You can give both input elements flex: 1 to make them fill the parent's width and on :focus make them flex: 2 or whatever you want:
#testForm {
padding: 0;
display: flex;
max-width: 600px;
}
#input1 {
background: red;
}
#input2 {
background: blue;
}
#input1,
#input2 {
flex: 1;
transition: all.5s ease;
}
#input1:focus,
#input2:focus {
flex: 2;
}
<form id="testForm">
<input type="text" id="input1">
<input type="text" id="input2">
</form>
A:
It is but you have to tweak some things.
Firstly, you have to set a width on your form not a min-width then set your :focus size to whatever is required.
However, input elements have a minimum size of 20 that has to be overridden in the HTML for the true effect to work.
An input element without a set width get its size from its size attribute, which defaults to 20.
* {
margin: 0;
padding: 0;
box-sizing: border-box;
}
#testForm {
padding: 0;
display: flex;
width: 600px;
border: 1px solid grey;
}
input {
flex: 1;
min-width: 0;
margin: 0;
border: none;
}
#input1 {
background: red;
transition: all.5s ease;
}
#input2 {
background: blue;
transition: all.5s ease;
}
#input1:focus {
flex: 20;
}
#input2:focus {
flex: 20;
}
<form id="testForm">
<input type="text" id="input1" size="5">
<input type="text" id="input2" size="5">
</form>
MECHANICAL VENTILATION: FROM HOSPITAL TO HOME
=============================================
The main objectives for mechanically ventilating a patient are to improve oxygenation, to increase or maintain minute ventilation, to help CO~2~ clearance, yet by decreasing work of breathing and protecting the airways.
Mechanical ventilators should be adjusted to influence the breathing rate and tidal volume by taking into account patient's physiology and interfaces' dead space.
In the Intensive Care Unit, common Indications for ventilation were reviewed by an international group in 2000 \[[@R1]\],
Hypoxemic respiratory failure 66%Acute exacerbation of COPD 13%Neuromuscular disorders 10%Coma 10%
There is a trend changing towards Non-Invasive Ventilation (NIV) \[[@R2]-[@R4]\], especially in the intermediate care units \[[@R5]\] and even more in the home environment \[[@R6]\]. This trend is described in the European survey of 2002: with improving patient status from the Intensive Care Unit to the Respiratory Intermediate Care Unit and the finally the Respiratory Monitoring Unit, more NIV is used \[[@R5]\].
Even if this epidemiology study mainly considers intermediate care units and not home care, home-care environment as place of care has quickly moved towards Non-Invasive Ventilation use \[[@R7]-[@R9]\].
The epidemiology of home mechanical ventilation was described in the EuroVent study \[[@R8]\]. This study reviewed the usage of home mechanical ventilation in 329 centres in 16 European countries including more than 16509 patients. The authors concluded wide variations in experience and care provision infrastructures between countries (Fig. **[1](#F1){ref-type="fig"}**).
After weaning from invasive ventilatory support and if the patient still requires additional support, long-term home non-invasive ventilation is a key choice for treating hypercapnic chronic respiratory failure patients in absence of socio-economic or medical constraints \[[@R10]\]. Clini and colleagues reviewed data from Italy comparing home NIV (with oxygen) with the cost care of oxygen alone. Hospital related costs were lower in the NIV group \[[@R11]-[@R13]\].
Using NIV in the home puts more stress on finding the appropriate settings for the patient on a specific ventilator. Successful ventilation does depend on reduces patient ventilator asynchronies. Asynchronies or more generally patient/ventilator respiratory disturbances may occur and may contribute to failure or discomfort.
PATIENT VENTILATOR INTERACTIONS
===============================
Guo and colleagues identified the patient/ventilator respiratory disturbances to be relatively frequent \[[@R14]\]. They described 4 types of respiratory events versus normal synchronous respiration on a ventilator (Fig. **[2](#F2){ref-type="fig"}**):
patient/ventilator desynchronization (Fig. **[3](#F3){ref-type="fig"}**),periodic breathing (Fig. **[5](#F5){ref-type="fig"}**),autotriggering (Fig. **[4](#F4){ref-type="fig"}**), andapnea-hypopneas.
Based on various publications, the percentage of asynchrony affects more than 1 out of 4 patients \[[@R15],[@R16]\]. The patient ventilator disturbances originate in various sources, including but not limited to bad ventilator performance, inadequate settings and non-intentional leaks. The non-intentional leaks are mostly due to bad mask fitting and have a deleterious effect on ventilator performance \[[@R17]-[@R23]\]. The choice of interface is critical to reduce the leaks and assure good ventilation \[[@R24]\]. Meyer *et al.*wrote about air leaks reducing sleep quality under non-invasive ventilation \[[@R25]\], but specifically the patient ventilator asynchrony that was caused by leaks was not considered. In recent times, patient ventilator asynchrony is being published as having a negative effect on sleep quality for patients using non-invasive ventilation \[[@R26],[@R27]\].
Manufacturers and clinical or university centres are performing studies to compare or to test ventilators in different conditions and thereby to assess in which conditions patient ventilator disordered breathings occurs.
Bench evaluations of mechanical ventilators are a comfortable way of assessing performance of devices in terms of triggering, cycling, monitoring and leakage behaviour \[[@R22],[@R28]-[@R36]\]. Indeed, technology also brought new developments in the bench design.
However, there are both many patient-specific criteria as well a variety of pathologies that makes this task self-limiting, as can be drawn from the bench evaluation designed for paediatric evaluation by the team of Fauroux \[[@R28]\]. Despite this limitation, bench testing allows repetitive evaluations under similar conditions which is not possible on patients. Indeed, comparison of ventilators on patients demands for a large population to be included with common pathology features to yield a statistically significant analysis else outcomes might be non-significant \[[@R37]\].
As written by Stroetz in 1998, "Practitioners willing to make the effort to interpret patient-ventilator interactions will find it difficult to manage ventilator-dependent patients without feedback from waveform analysis in the future"\[[@R38]\].
This was illustrated by example in a case report by Haynes \[[@R39]\]: by using the waveform display on a Pressure Support ventilator, he was able to detect asynchrony and manipulate inspiratory risetime and breath-termination criteria to improve the patient ventilator synchrony.
Even though use of waveforms to reduce patient ventilator respiratory disturbance has become common in the Intensive Care setting \[[@R40]-[@R43]\] and sub-acute/monitoring centres, waveforms could sometimes be difficult to interpret for clinicians not routinely using them. Some computerized algorithms exist for the intensive care setting where patients are deemed more under control \[[@R44]-[@R46]\]. Alternative automated methods are being developed specifically for non-invasive ventilation. As an example a, entropy based analysis developed in Rouen \[[@R47]-[@R49]\] or an algorithm validated in Nava's team \[[@R16]\].
The entropy based system is using a novel algorithm calculating phase portraits and entropy (mostly used in chaos techniques). It looks at the variability of ventilation and triggering efforts. This method is post-hoc by design but could still yield very useful information for the caregiver to adjust the settings (Fig. **[6](#F6){ref-type="fig"}**).Another algorithm detects ineffective triggering as perturbations in the expiratory flow unaccompanied by a mechanical breath (Fig. **[7](#F7){ref-type
|
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}Why a House is Not a Good Investment – Real Estate Investing with Grant Cardone Sneak Preview
How will election affect real estate market?KTUL(KTUL) -- They are the campaign signs of real estate, and in Tulsa, they're giving those political signs a run for their money. The real estate market is currently booming in Tulsa. Even with the election right around the corner, but experts say that...IPPP/05/35\
DCPT/05/70\
27th June 2005\
[**Diffractive Processes at the LHC**]{}[^1]\
M.G. Ryskin, A.D.Martin and V.A. Khoze\
Petersburg Nuclear Physics Inst., Gatchina, S.Petersburg, 188300, Russia\
and\
Inst. for Particle Physics Phenomenology, Durham University, England\
We consider diffractive processes which can be measured at the LHC. Analysis of diffractive events will give unique information about the high energy asymptotics of hadron scattering. In semihard diffraction one may study the partonic structure of the Pomeron. Central Exclusive Diffractive production provides a possibility to investigate the new particles (Higgs bosons, SUSY particles,...) in an exceptionally clean environment.
Introduction
============
It was shown about 40 years ago that the behaviour of the diffractive cross sections, together with the crucial role played by unitarity constraints, determine the high energy asymptotics of hadron-hadron interactions. The LHC collider is the first accelerator which will have enough energy to produce the events with a few ($n=2 - 4$) large rapidity gaps. This will be the first time we could measure diffractive and multi-Pomeron processes sufficiently close to their asymptotic regime.
Our discussion is based on the ideas (and publications) of V.N. Gribov. Remarkably, Gribov played the pivotal role in investigating almost all aspects of this field. He introduced the Reggeon diagram technique [@RDT]. He discussed in detail the possible high energy behaviours of hadron interaction amplitudes [@weak; @strong]. He found the relations between the diffractive and inelastic cross sections [@AGK] — the AGK cutting rules. He discovered the constraints on the diffractive amplitudes coming from the unitarity conditions, and the specific asymptotic behaviour of the elastic cross section [@const].
Our brief review is divided into three parts. First, we discuss pure [*soft*]{} interactions: the behaviour of the total cross section and the slope of differential elastic cross section, the $t$-dependence of the diffractive dissociation and the survival probability of one (or a few) large rapidity gaps. Next, we consider the [*semihard*]{} diffractive processes, where high $E_T$ jets or a heavy boson (e.g. $J/\psi$, $W, Z$,...) may be produced. Finally, we describe the advantages of studying New Physics (in particular Higgs bosons) in Central Exclusive Diffractive (CED) events.
Soft diffractive events
=======================
Unitarity constraints for elastic amplitude
-------------------------------------------
It is known that the present data on high energy elastic hadron-hadron scattering are well described by a simple parametrization proposed by Donnachie and Landshoff (DL) [@DL]. The nucleon-nucleon amplitude is written as $$A(s,t)~\simeq~ i\sigma_0 ~ F_1^2(t) ~ (s/s_0)^{\alpha_{\Pom}(t)},
\label{eq:DL}$$ where $s$ is the square of the incoming c.m. energy ($s_0=1$ GeV$^2$), $F_1(t)$ is the electromagnetic proton form factor ($t$ is the momentum transfer squared), and the Pomeron trajectory $\alpha_{\Pom}(t)=1.08+t\cdot 0.25$ GeV$^{-2}$. The corresponding cross section is $$\sigma=(1/s)\mbox{Im}A(s,0)\propto
\sigma_0(s/s_0)^{0.08}.$$
It is convenient to transform (\[eq:DL\]) to impact parameter, $b_t$, space $$A(s,b_t)\,=\,\frac{-i}{2s(2\pi)^2}
\int A(s,t=-q^2_t)~e^{i\vec q_t \cdot \vec b_t}~d^2q_t$$ If the power growth ($\sigma\propto s^{0.08}$) continues, then the amplitude, which at the Tevatron reaches $A(s_{\rm Tev},b_t=0) \simeq 0.96$, will exceed the black-disk limit at the LHC, $A(s_{\rm LHC},b_t=0)>1$.
In the DL approach the high energy amplitude is described by single Pomeron () exchange only. To account for the unitarity constraints, we must include multi-Pomeron diagrams. In particular, the KMR model [@KMRsoft], which accounts for multi-Pomeron contributions, and successfully describes the same data in the ISR – Tevatron energy range, predicts $A(b_t=0)<1$ (but close to 1) at the LHC energy. However in such models [@KMRsoft; @KPT], due to the multi-Pomeron effects, the interaction radius $R^2$ (that is the elastic slope $B(t=0)$) grows faster than that in DL model. At the LHC energy, $B_{\rm KMR}\sim 22$ GeV$^{-2}$, while $B_{\rm DL}=19$ GeV$^{-2}$ (see [@KMRcetr] for more details). Thus it will be important to measure the elastic slope (i.e. interaction radius) at the LHC, since the unitarity-induced corrections caused by the multi-Pomeron cuts, first reveal themselves in the value of the slope $B$.
Possible asymptotics of the high energy amplitude
-------------------------------------------------
Detailed analyses performed at the end of 60’s [@weak; @strong] had showed that there could be a few different regimes with different energy dependences of the cross section $\sigma_{\rm tot}$ as $s\to\infty$.
- $\sigma\to {\rm const.}$ – the so-called ‘weak coupling’ regime [@weak].
In this case, as $s\to \infty$, the major contribution comes from -pole exchange, while the -cut contribution dies out; the elastic slope $B\propto {\rm ln}~s$.
- $\sigma\sim ({\rm ln}~s)^\epsilon$, $B\sim({\rm ln}~s)^\eta$ with $0< \epsilon \le \eta < 2$ – the ‘critical Pomeron’ [@strong].
- $\epsilon=\eta=2$ – the ‘supercritical Pomeron’, which leads to the Froissart regime.
In terms of the bare -pole, the critical and/or supercritical Pomeron amplitudes are -cuts in which the single -contribution is completely screened by multi-Pomeron rescatterings.
- Finally, it may be possible for the cross section to first grow as $\sigma_{\rm tot}\propto s^\epsilon$, but then at larger energies to decrease like $s^{-\epsilon}$, due to the increasing role of Pomeron-Pomeron self-interactions (see for example [@Bor]).
Surprisingly, this last possibility is still allowed by the present data! The Tevatron energy is not sufficient to reject it, since the transition to the $\sigma\sim s^{-\epsilon}$ behaviour is expected to occur only after the possible size of the rapidity gap becomes much larger than $1/\epsilon\sim 12$ (for $\epsilon=0.08$).
Diffractive dissociation and the triple- vertex
------------------------------------------------
The diffractive dissociation into a high mass ($M_X$) state is described by the triple-Pomeron diagram. If we assume that the triple-Pomeron vertex $G_{3\Pom}$ is just a small constant, then we face a problem. In this ‘naive’ approximation the cross section of diffractive dissociation $\sigma^{\rm SD}$ grows faster than $\sigma_{\rm tot}$. This applies to cases (a), (b) and (c) above. Indeed, even for $\alpha_{\Pom}=1$, after the integration over the mass $M_X$ ($\int^s
dM^2_X/M^2_X\sim \ln s$), the cross section $\sigma^{\rm SD}\propto
({\rm ln}~s)\sigma_{\rm tot}^2 > \sigma_{\rm tot}$. An analogous, and more severe, problem occurs in processes with so-called multi-Reggeon kinematics. The cross section of the events with a few large rapidity gaps grows faster than
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] |
produce), we make sure to remove them with the instruction <code>Update.onUpdate (Html.filter (not << Html.isEmptyText))</code>.
This instruction is the last one because it will be the first to execute when the program executes in reverse.
Note that the <code>main = </code> is optional, if the program ends with an expression, it will automatically insert <code>main = </code> in front of it.
Great. You can try to rename "dog" in the output to see that the rename propagates to the corresponding <code>Image</code>.
Now, time to import the images.
On the website, right-click on the table. In major browsers a menu item "Inspect" or "Inspector" will lead you to a developer console that will display the source code of the page at this point. To display the actual source code, you might have to right-click the element again and "edit as HTML".
Now select the first 8 rows in the Html source. A row starts with <tr> and ends with </tr>.
Alternatively, you can copy the rows from the box below.
@t.displaylocalcode<|"""<tr>
<td><img src="/images/kitchen/034.jpg"></td>
<td>barbecue</td>
</tr>
<tr>
<td><img src="/images/kitchen/024.jpg"></td>
<td>bread basket</td>
</tr>
<tr>
<td><img src="/images/kitchen/037.jpg"></td>
<td>cake slice</td>
</tr>
<tr>
<td><img src="/images/kitchen/007.jpg"></td>
<td>champagne cooler</td>
</tr>
<tr>
<td><img src="/images/kitchen/020.jpg"></td>
<td>chest freezer</td>
</tr>
<tr>
<td><img src="/images/kitchen/035.jpg"></td>
<td>coffee machine</td>
</tr>
<tr>
<td><img src="/images/kitchen/032.jpg"></td>
<td>cooker, stove</td>
</tr>
<tr>
<td><img src="/images/kitchen/006.jpg"></td>
<td>corkscrew</td>
</tr>"""
Once you have this data is in the clipboard, click on the "Html" button to the right of the Sketch-n-sketch interface to see the source code as html. Paste the clipboard contents right after the last <code></tr></code>.
The popup "Output Editor" appears; hover over "Update program" and click on the first solution.
The variable 'images' is now populated.
You've successfully imported data that would have normally required the use of regular expressions or custom programs to parse.
You now need to fix the URL of the images you imported, because they are relative.
In the code, <b>delete the first row</b> containing the information about the dog (and the comma in front of the second entry).
@t.hiddenreplace("""images = [
Image "dog" "https://upload.wikimedia.org/wikipedia/commons/7/7d/Labrador_Chocolate.jpg"
]""")<|"""images = [
Image "barbecue" "/images/kitchen/034.jpg"
, Image "bread basket" "/images/kitchen/024.jpg"
, Image "cake slice" "/images/kitchen/037.jpg"
, Image "champagne cooler" "/images/kitchen/007.jpg"
, Image "chest freezer" "/images/kitchen/020.jpg"
, Image "coffee machine" "/images/kitchen/035.jpg"
, Image "cooker, stove" "/images/kitchen/032.jpg"
, Image "corkscrew" "/images/kitchen/006.jpg"
]"""
@t.replace("""img src=url""")<|"""img src="https://www.englisch-hilfen.de"+url"""
You should now obtain the following table:
@t.displayevalcode
FYI: the source code at this point is:
@t.displaycode
## Design the logic
We want to create two cards for each image, one for the name,
the other for the picture. We will then shuffle these cards and,
using css tricks, display them 'face down' on a 4x4 grid.
With the power of Javascript, we will handle clicks and even
show a modal dialog to congratulate the player at the end.
Fortunately, we coded all of this in Javascript and CSS
for you so you just need to do some replacements.
First, the logic for building the deck.
@t.replace(placeholder 1)<|"""@(placeholder 2)
g = random.generator (random.seedOf 1)
pairs = images
|> List.indexedConcatMap (\i (Image name url) -> [(i, Named name), (i, Image url)])
|> flip g.shuffleList_ (\_ list ->
list |> List.map (\(i, elem) -> case elem of
Named name -> card i <span>@@name</span>
Image url -> card i <img src=("https://www.englisch-hilfen.de"+url)>)
)
card i child =
<div class="flip-container" num=i
ignore-selected="false">
<div class="flipper">
<div class="front"
onclick=@(q3)if(@@(isOkToSelect "this.parentNode.parentNode.parentNode")) this.parentNode.parentNode.setAttribute('ignore-selected', '' + (this.parentNode.parentNode.getAttribute('ignore-selected') == 'false'));@@(checkPair "this.parentNode.parentNode.parentNode")@q3></div>
<div class="back">@@child</div>
</div>
</div>
"""
Now, we add the css and javascript for displaying the deck.
@t.replace("""main = <table>...</table>""")<|"""main = Html.forceRefresh <div>
@buttonPlaceholder The game is in English.
<div class="pairsContainer">
@@pairs
<div id="successBox" class="modal" ignore-visible="false">
<div class="modal-content">
<span class="close">×</span>
<p>Congratulations! You finished the memory game.</p>
</div>
</div>
</div>
<style>@@css</style>
</div>
css = @q3
.pairsContainer {
max-width: 535px;
margin: 10px;
outline: 2px solid #8A9;
outline-radius: 2px;
padding: 2px;
padding-left: 5px;
background: #AFC
}
/* Credits to https://davidwalsh.name/css-flip */
/* entire container, keeps perspective */
.flip-container {
perspective: 250px;
display:inline-block;
}
/* flip the pane when clicked */
.flip-container[ignore-selected=true].flipper {
transform: rotateY(180deg);
}
.flip-container,.front,.back {
width: 128px;
height: 128px;
margin: 2px;
}
/* flip speed goes here */
.flipper {
transition: 0.6s;
transform-style: preserve-3d;
position: relative;
}
/* hide back of pane during swap */
.front,.back {
backface-visibility: hidden;
position: absolute;
top: 0;
left: 0;
}
/* front pane, placed above back */
.front {
z-index: 2;
/* for firefox 31 */
transform: rotateY(0deg);
background-image: linear-gradient(to top left, #F00, #FF0);
}
/* back, initially hidden pane */
.back {
transform: rotateY(180deg);
text-align: center;
display: inline-table;
font-size: 20px;
background-image: linear-gradient(to bottom right, #EEE, #CCC);
display: flex;
align-items: center;
justify-content: center;
}
.back > span {
display:table-cell;
vertical-
|
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tumours in Africa than in Europe. In Tanzania, for example, 56.4% have tumours with histological grade 3 \[[@B5]\], while, in Nigeria, 45.1% have grade 3 tumour \[[@B18]\]. On the contrary, only 15.8% of Finnish women have a grade 3 tumour. Most women in Europe present with a grade 1 or 2 tumour \[[@B17]\]. African-American women are also considerably more likely to have high grade nuclear atypia, grade 3 tumours, increased number of positive nodes, and more necrosis than white women \[[@B19]--[@B21]\]. Black British women have been shown to have higher rates of grade 3 tumours and lymph-node-positive disease than white British women \[[@B9]\]. This may explain why the progression of breast cancer is more aggressive in African women than in European women.
Gene expression analysis has been used to classify breast cancer into various subtypes. These include luminal A, luminal B, basal-like, HER2+/ER−, and unclassified. Basal-like breast tumours occur at a significantly higher rate among premenopausal African-American patients compared with postmenopausal African-American and non-African-American patients \[[@B22]\].
6. Stage at Presentation {#sec6}
========================
There is a significant difference in staging at the time of presentation between European women and their African counterparts. Most women in Africa present when the disease is at an advanced stage. In a study in East Africa, more than 70% of the patients presented at stage III or IV \[[@B5]\]. In studies in Libya and Nigeria, more than half of the patients presented at stage III or IV \[[@B17], [@B18]\]. However, in Europe, women are more likely to present when the disease is still in its early stage \[[@B23]\]. In a Nigerian study, as high as 39% of the patients had fungating tumours while 13% had clinical evidence of systemic metastasis \[[@B4]\]. The reason for the advanced presentation in Africa could be due to lack of health care coverage especially in remote rural areas and poverty as healthcare is not free in most countries. On the contrary, in most European countries, healthcare is easily accessible and free. In addition, public awareness is high and screening is available in most European countries.
7. Breast Cancer Genes (BRCA1 and BRCA2) {#sec7}
========================================
Breast cancer susceptibility genes 1 and 2 (BRCA1 and BRCA2) are tumour suppressor genes, and mutation of these genes has been shown to be associated with an increased risk of developing breast cancer. These genes have been demonstrated to contribute to an increased risk of breast cancer among European women. In a study in Sweden, BRCA mutations were more frequent among case subjects with one first- or more than one first- or second-degree relative with breast or ovarian cancer (*P* \< 0.001) than among subjects without this degree of family history \[[@B24]\]. In addition, BRCA mutations were statistically significantly more common among women with bilateral breast cancer than among women with unilateral breast cancer (*P* = 0.002) \[[@B24]\]. Research has even suggested that the age of onset of breast cancer tends to be younger in BRCA1 mutation carriers than BRCA2 mutation carriers \[[@B25]\]. Unfortunately, much research has not been done on the possibility of genetic predisposition to breast cancer among native African women in the African continent.
8. Management {#sec8}
=============
As many breast cancer cases are detected early in Europe, many of the women could have breast conserving surgery (BCT). In Poland, for example, the number of tumours detected with diameters ≤5 cm increased from 57% in 1984 to 81% in 2003 \[[@B26]\]. On the contrary, in Africa, only 52% of the patients have tumour size below 6 cm \[[@B5]\]. As a result, most women in Africa have mastectomy and adjuvant hormonal therapy or chemotherapy and many others only receive palliative care because the tumour is advanced and inoperable.
9. Discussion {#sec9}
=============
Breast cancer is increasing in regions that until recently had low rates of the disease. However, the incidence of the malignancy is still low in Africa compared to the incidence in Europe. This has largely been attributed to a protective reproductive history including late menarche, early menopause, high parity with prolonged breastfeeding, irregular menses, and fewer ovulatory cycles \[[@B27]\]. However, it has been reported that African women tend to present at an earlier age and the disease appears to be more aggressive than in their European counterparts. This could be due to certain genetic predisposition. Unfortunately, much genetic work has not been done on nonmigrant African women, although some research has been done in their African-American counterparts. In an American study, most African-American patients had mutations in BRCA2 while most mutations in the white cohort were in BRCA1 \[[@B28]\]. The study further stated that almost half of the African-American women had variants of uncertain significance, compared to only 12% of the white cohort \[[@B28]\]. In addition, Black women in Europe exhibit similar pattern of disease to African women than to white European women suggesting that genetics may be playing a more significant role. The higher prevalence of basal-like breast tumours and a lower prevalence of luminal A tumours could also contribute to the poor prognosis in young African-American women with breast cancer. It would be of immense benefit if there could be research into the genetics of breast cancer among African women in various regions of the African continent. Such research might even reveal mutations that are currently unknown.
African-Americans have the highest rates of premenopausal breast cancer, and it has been suggested that this might be linked to hormonal levels such as oestrogen \[[@B29]\]. Oestrogen stimulates cell division, and, therefore, the higher the exposure of a woman to oestrogen, the higher the rates of cell division in the breast. A high rate of cell division predisposes humans to DNA copying error, resulting in higher risk of cancer. Studies have shown that African-American women have higher levels of oestradiol, free oestradiol, and IGF-1, all of which have been attributed to a higher risk of breast cancer. SHBG reduces the risk of breast cancer and the fact that postmenopausal African-American women appear to have a higher level of SHBG may explain why Black women both in and out of Africa are at a lower risk of breast cancer after menopause. However, other risk factors may combine to increase the risk of breast cancer in postmenopausal Caucasian women.
The high mortality from breast cancer in Africa could be attributed to poverty. In most parts of Africa, health care is not free, and, as a result, women delay before presentation to hospital. It is not uncommon for them to have used unorthodox medicine before eventually visiting the hospital. In many instances, the disease would have reached an advanced stage. This is in contrast to most European countries where health care is not only free, but also regular screening is available to women of certain ages. This increases the probability of detecting breast cancer at a very early stage. In the United Kingdom, for example, women aged 50--70 years are invited for breast screening with mammography every three years \[[@B30]\]. In addition, the National Institute of Clinical Excellence (NICE) has stated that women who are known to have a genetic mutation should be offered annual MRI surveillance if they are BRCA1 and BRCA2 mutation carriers aged 30--49 years and TP53 mutation carriers aged 20 years or older \[[@B31]\]. In France, regional breast cancer screening programmes are being offered to women aged 50--74 years. Unfortunately, this is not the practice in many African countries.
The poor health care system in Africa also affects the management of breast cancer patients. Many women in Africa are unable to undergo breast conserving surgery (BCT) because of lack of radiotherapy facilities. To perform a breast conserving surgery, radiotherapy would be required after surgery \[[@B32]\]. As a result, a significant number of African women with breast cancer have to undergo mastectomy. This is in contrast to Europe where many breast cancer patients are able to have their breast conserved \[[@B33]\] because of the availability of radiotherapy facilities. In Africa, mastectomy rate is more than 85% \[[@B4]\], compared to just 30% in Europe \[[@B33], [@B34]\]. In fact, in the UK, more than 70% of screen-detected breast cancer patients have BCT \[[@B34]\]. There are only 4 radiotherapy centres in Nigeria, with a population of 160 million, compared to the UK that has a population of 60 million and more than 70 radiotherapy centres.
There must be political will on the part of African leaders to adequately fund the health care system. To optimise the management of breast cancer patients, there must be access to radiotherapy facilities and cytotoxic drugs must be readily available. Imaging facilities such as computerised tomography (CT) and magnetic resonance imaging (MRI) must be readily available at no cost to the patient or at an affordable rate.
As it appears that Black women, both within and outside Africa, have a higher incidence of premenopausal breast cancer, it might be worth considering lowering the age at which Black women are first invited for screening in countries that have a breast cancer screening programme so as to detect malignant changes as early as possible.
10. Conclusion {#sec10}
==============
The epidemiological similarities and differences in breast cancer among women in Europe and Africa have been reviewed. There should be more research at the molecular level among African women to identify genetic factors that may contribute to the risk of developing breast cancer. There should also be improvement in the health care system in Africa in order to optimise care for women with breast cancer.
[^1]: Academic Editor: P. Vineis
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body. God, he loved waking her like that.
He pumped in and out of her body, picking up the pace and adding a second finger to her pleasure. She reached behind her, slid her hand into his scrubs and grasped his erection, hard. She squeezed him and matched his rhythm stroke for stroke. They both moaned and groaned loudly, obliviously to whatever could burst through their office door.
Ryan got lost in his girl. His woman got lost in his touch. This is how they worked well together. This is what they were. A perfectly matched couple who couldn’t get enough of each other.
She got to her climax point quick, her body clenched around his fingers and exploded. Her pleasure sent him over, exploding into her dainty palm with a loud groan as he bit her shoulder to try to muffle his sound.
“Shit, Lynn,” he breathed. “I need to change my work clothes.”
She laughed. “Thank goodness I think ahead. I’ve got a change for you in my bathroom.”
She was perfect.
“Marry me,” he said.
She pulled her hand out of his scrubs, wiped them off on his now soiled material, and fluttered her ring finger. “I’ve already said yes.”
“I mean now,” he clarified.
“What?”
“It’s been how long since I asked? The daycare is up and running. My health is back to normal. There’s no reason to wait.” He repositioned her to look him in the eyes.
“Where do you want to get married? It takes so long to plan a wedding. Over a year. I don’t have that kind of time,” she said and bit her bottom lip.
“We can go to a JP and have a small dinner afterwards. Just family,” he said.
“Are you sure?”
“I’ve never been more positive about anything, Lynn,” he answered confidently, because it was true. He loved her to his core. There were no more excuses to keep them from becoming husband and wife. Well, except for whatever she decided to come up with.
“Okay,” she said. “Let’s do it.” He took her mouth in a blazing kiss. His heart felt like it could explode. Never in his life did he think he’d be at this moment. In love with a woman he wanted to spend the rest of his life with.
A knock on the door interrupted them.
“Are you finished?” his brother’s mocking tone came through the wood door.
“For fuck’s sake,” he growled.
Lynn jumped up and straightened her clothing. “I’m going to need to change.”
She rushed to the door to open it while he slid into the bathroom and quickly changed his clothing. When he came back out into the office, Sean had his twin girls with him. Ryan scooped up Morgan. Both girls were still tiny things at nine months old.
“Where’s Lynn?” he asked.
Sean took Michelle out of her carrier. “She went to do a round and check on everything.” His brother cocked a brow. “Really, in the office of a daycare?”
Ryan shrugged negligently. “Don’t really want to hear it from you because I know for a fact you fuck your wife anywhere you can get your hands on her.”
“First,” Sean growled, “do not use that language around my girls. Second, we have twins. If I don’t, then how can I possibly get her pregnant again?”
“You want a son,” he accused his brother.
“I want to try for a son,” Sean countered.
Ryan snorted. “That’s entirely up to you.”
He burst out laughing at his sap of a brother, who reached out and nailed him in the low back.
“Sean, I’m holding your daughter,” he strained.
“And you better not drop her,” his ass of a brother warned.
Ryan wanted to toss out a curse but bit his tongue. Sean was right, they had to watch their language around the girls and Brady, his son who was only about six weeks older than the girls.
“Lynn’s finally agreed to marry me,” he said, rubbing his back.
Sean snorted. “She agreed a long time ago.”
“No, I mean, now.”
Sean perked up. “Really?”
“Yeah,” he answered. “Will you be my best man?” he asked, a lump in his throat he coughed out.
His older brother, the one who’d always been by his side, approached him, grasped the back of his neck and touched foreheads. Something they’d done countless times when they served as US Navy SEALs together. “I’d be proud to stand next to you.” Sean kissed his forehead. “You make me proud to be your brother, you know that?”
Ryan couldn’t respond, too choked up over how his brother and now his soon-to-be wife changed his life for the better.
2
“I know,” Ryan said, his head falling to the dining room table.
“How can you not invite Courtney?” Lynn asked baffled. “She’s going to be devastated.”
Ryan repositioned Brady to his right leg and bounced him while they ate their late dinner. To say he was in a predicament was an understatement. Marrying Lynn wasn’t going to be a large affair where they could keep Courtney and Sean separated. They were going to be in one small room in front of the local judge and then have an intimate dinner at a fine dining restaurant. Attending would be his gorgeous bride and himself, Sean and Beth with the girls, his parents, and Lynn’s brother Russ and cousin Jarrett as well as her parents. There’d be no place to keep the two cousins, who were still at odds, from going at each other’s throat. And they would. Because it would be a couple hours in close quarters and Courtney would no doubt push Sean to try and mend their relationship. Unfortunately his sometimes mule-headed brother wasn’t ready to forgive yet. Who knew what it would take to fix that mess?
“Did he ask you not to invite her?”
He shook his head.
“Then you should.” Lynn snatched Brady off him.
His son wrapped himself around his soon-to-be stepmom. Lynn vowed to adopt Brady as soon as they were married, which would change her title. It would take some time and money, but the fact she was willing to do it meant the world to him.
He sighed and raked a hand down his face. Why did this have to be so stressful?
“At least talk to Sean about it,” she said.
“Talk to Sean about what?” his brother asked, waltzing into the room with Morgan in his arms. Beth followed behind with Michelle.
“Are you both hungry?” Lynn asked. “I can grab you a plate. There’s plenty of spaghetti for everyone.”
“I am,” Beth said softly. “I didn’t get to eat lunch today.” She gave Sean a pointed look.
Sean shrugged. “We had the office to ourselves for a few minutes.”
Lynn smacked him upside the head as she handed him Brady to get Beth her dinner. “Stop flirting with my sister-in-law. Ass.”
Sean smacked him on the other side of his head. “Stop hitting on my wife.”
“Jesus.” Ryan rubbed the back of his head.
“Some habits die hard, don’t they, Ryan?” Beth chuckled.
He winked her direction. Yeah, they did.
“Talk about what?” Sean asked again. Leave it to his brother to never allow a subject to drop.
Ryan sighed heavily, closed his eyes, and prayed for peace. “Inviting Courtney to the wedding.”
He opened one eye to peek at his older brother. Sean didn’t disappoint. He face turned into a blank mask. Which meant he was hiding his anger. It was Sean’s tell. Beth looked at Ryan sympathetically. His sister-in-law was too kindhearted and forgave Courtney for the argument they had. But Beth understood her husband too well and knew she couldn’t broach the subject of a family reunion. They’d done it once and it hadn’t gone well. Anything more than that would push Sean over an edge.
“I would never tell you not to invite her, Ryan,” Sean said.
“But things would be tense,” he said.
Ryan bounced Brady on his leg and straightened the M&M costume he dressed him in this morning.
“I’ll keep him in line,” Beth said quietly.
Sean snorted.
Ryan laughed at his brother. “Who are you kidding? These three women rule you.”
Sean collapsed back in the chair resigned and smiled. “Yeah, they do.”
Ryan knew the feeling all too well. He totally got Sean’s acceptance of that trait.
3
Ryan stood nervously in his black suit next to his brother, who stood in front of Judge Waters. How ironic the man who’d married Derrick and Courtney was going to marry Lynn
|
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16315,
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18438,
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3348,
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34699,
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14799,
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1983
] |
otype most likely at B and destroyed; Lectotype here designated as W\* (W1889-0050720); isolectotypes: G00495616\*, HAL0110867\*, M0029893\*, P02505554\*, W0064359\*, & W0064360\*\]. [@B29] listed the date of the field trip as 1827--1829 and she listed additional possible locations of herbarium material as: B, BR, CGE, F, FI-W, GOET, K, KIEL, L, LE, LZ, MO, NY, OXF, PR, PRC, US, WRSL.
Lessing's descriptions seem to be based on specimens that he examined at B. They were most likely collected by B staff/associates or sent to B as a gift/exchange. The Compositae herbarium at B was destroyed during WWII ([@B10]) so when duplicates can be found they are designated as lectotypes. Lessing participated in two series of papers about Compositae in the journal *Linnaea*. The title of Lessing's first series of papers in *Linnaea* was *Synanthereis Herbarii Regii Berolinensis* ([@B14], [@B15], [@B16], [@B17]). The second series included two papers by [@B18], [@B19]), the latter of which included the type description of *Adenocaulon chilense*. These two articles were part of a larger series entitled *De plantis in expeditione speculatoria Romanzoffiana observatis disserere pergunt AD. de Chamisso et D. de Schlechtendal*, and although Chamisso's original collections were no doubt at LE and Schlechtendal's at HAL they both probably sent duplicates to B and it is likely that Lessing worked from the duplicate material. Interestingly the "Romanzoffiana" treatment is part of a larger series of papers that began in volume 1 of *Linnaea* ([@B6]). In his preface [@B6] says that the exploratory expeditions were supported by Count de Romanzoff the Imperial Chancellor in 1815, hence the name of the article. The preface mentions other collectors but does not mention Poeppig. Poeppig's original set is supposed to be at W ([@B29]) and it is likely that a duplicate was sent to B. There are two collections at W (E. Vitek, pers. comm.) and one has been selected as the lectotype.
There is some confusion as to the collecting number: on many specimens there are two numbers, the number of the printed labels differing somewhat from the "diario" numbers that are often handwritten. As a result, some records for this particular collection have the number 755 but others list 255 (likewise JSTOR-GP entries list one or the other). Some specimens clearly have both 755 & 225 printed on the labels and others do not. It is possible that the collecting number is 755 as it appears handwritten on the lectotype (and on the printed lables as "diar. 755") and other type material has 255 printed on the labels and this may be a species number. Vitek (pers. comm.) provided an example of how the collecting number might be cited and we have followed that.
*Adenocaulon lechleri* C.H. Schultz Bipontinus, Flora 38: 113. 1855. Type material. Chile. Ad portum Port Famine, s.d. \[1850--1853\], *W. Lechler 1245* \[Holotype: P02505548\* ex Herb. Sch. Bip.; isotypes, BR0000005630134\*, G00222157\*, G00222158\*, G00222159\*, GH00000617\*, M0029894\*, M0029895\*, NY00158067\*, P02505546\*, P02505547\*, P03313093\*\]. On JSTOR-GP there is specimen from K from *Herbarium Hookerianum* collected by Lechler (s.n.) but with a date of 20 January 1854 and a different location. This is not believed to be type material. [@B7] gave the dates of this trip as 1850--1853.
*Boerhavia nudicaulis* R.A. Philippi, Linnaea 29: 37. 1857. Type material. Chile. Chillán, 1 Dec 1855, *P. Germain s.n* \[Holotype: SGO000001680\*; isotypes: G00414903\*; K000500419!. K000500419 is not listed as a type in JSTOR-GP and the date printed on the label is '1856 et 1857", but it has the correct location and was originally identified as *Boerhavia nudicaulis* so it is probably an isotype.\]
According to Lanjouw and Stafleu (1957), Germain was in Chile 1854--1890 and they indicated that there may be additional specimens at BM, F, FI, P, W and Philippi types may be at BAF (no reply).
### Adenocaulon himalaicum
Plantae
Asterales
Asteraceae
M.P. Edgeworth
1. Adenocaulon himalaicumM.P. Edgeworth, Transactions of the Linnean Society of London 20: 64. 1851.
#### Type material.
Himalaya in sylvis, 7000--9000 ft, between Nagkanda and Kotgurh \[India, Himachal Pradesh\], 1844, *M.P. Edgeworth 15* \[Holotype: K000250901!; Probable isotypes: K! K000250901, OXF\* (OXF00005487, not yet available in JSTOR-GP)\].
The printed label on the Holotype has a date of 1844, the OXF sheet has the handwritten date of Oct 1840, and the K isotype has no date. TL2 ([@B25] and Lanjouw and Stafleu 1957) indicated that an additional specimen maybe at G-DC (not found, pers. comm. Loze). Only the K specimen has a printed label with a date and a "collecting number" so these may have been added by Kew. Since dates on these older specimens are often mixed up it seems likely that the second K specimen and the OXF specimen are isotypes.
### Adenocaulon adhaerescens
Plantae
Asterales
Asteraceae
C.J. Maximowicz
1. Adenocaulon adhaerescensC.J. Maximowicz, Primitiae florae Amurensis: 152--154. 1859.
#### Type material.
Russia, Amur, \[7 July 1855\], *C.J. Maximowicz s.n.*
Amur is an area in Siberia (Russia) near the border with China. Vegter (1976) indicated that Maximowicz went to Amur in 1854--1856 and again in 1859--1860 but the latter years are too late for this species description. The lectotype selected below has the date of 7 July 1855 on the label.
According to the protologue there are five syntypes all collected by Maximowicz from Amur, the Khabarovsk Region of Russia. Maximowicz worked at LE and so the material he used to describe this species should be there.
**Syntype 1.** Borbi (an Nadelholzrändern, 27 June fl. pr.) \[Borbi, Russia: 51.24, 139.36; 14 Km SSE of Tsimmermanovka and the Amur River ([@B1])\]
**Syntype 2.** Ussuri-Mündung \[mouth of the Ussuri River\], Wäldern, and especially frequent in Waldstegen, Poddale, 20 May (sterile)
**Syntype 3.** Chungar \[Khungari River\], 11 July (fl. pr.) Lectotype here designated: LE01013892\* (not yet available in JSTOR-GP); Isolectotypes: H1023222\*, K000768768!, S0940878\*)
**Syntype 4.** Dshare \[mouth of "Dondon" (now Anyuy) River\], 18 July (flor. et frf.)
**Syntype 5.** Ssargu \[now Sharga Lake\], 14 July 1855 (fl. et defl.)
Syntype 3 was selected as the lectotype because the location, day and month are the same as those listed in the protologue. All other specimens either had no information on the actual sheet or conflicting information. Vegter (1976) listed other herbaria that might hold type material: L, NY, PU, W.
### Adenocaulon lyratum
Plantae
Asterales
Asteraceae
S.F. Blake
1. Adenocaulon lyratumS.F. Blake, Journal of the Washington Academy of Sciences 24: 435--436. 1934.
#### Type material.
Guatemala. In open woods, Chichavac, Dept. Chimal
|
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] |
stdout' to stdout,'stderr' to stderr, merges the two streams, and captures both outputs correctly:
source
import subprocess
res = subprocess.check_output(
"echo stdout; /bin/echo stderr 1>&2",
shell=True,
stderr=subprocess.STDOUT,
)
print 'DATA:', res.replace('\n', '.')
print 'END'
output
DATA: stdout.stderr.
END
import React from'react'
import PropTypes from 'prop-types'
import SVG from './SVG'
const MdPricetag = props => {
return (
<SVG
style={props.style}
className={props.className}
fill={props.color}
width={props.fontSize}
height={props.fontSize}
viewBox="0 0 1024 1024"
onClick={props.onClick}
rotate={props.rotate? 1 : 0}
shake={props.shake? 1 : 0}
beat={props.beat? 1 : 0}
>
<path d="M832 128h-316.8l-362.2 375.2c-16 16-24.6 37-25 58-0.6 22.6 7.8 45.2 25 62.4l247.4 247.2c16 16 41.6 25 57.6 25s45.6-7.8 62.8-25l375.2-358.8v-320l-64-64zM770.6 333.4c-43.4 12.2-82.6-20-82.6-61.4 0-35.4 28.6-64 64-64 41.4 0 73.6 39.2 61.4 82.6-5.8 20.6-22.2 37-42.8 42.8z"></path>
</SVG>
)
}
MdPricetag.defaultProps = {
// style
style: {},
color: '#000000',
fontSize: '22px',
// animation
shake: false,
beat: false,
rotate: false,
}
MdPricetag.propTypes = {
// style
style: PropTypes.object,
color: PropTypes.string,
fontSize: PropTypes.string,
// animation
shake: PropTypes.bool,
beat: PropTypes.bool,
rotate: PropTypes.bool,
// functions
onClick: PropTypes.func
}
export default MdPricetag
Comparison of small area techniques for estimating prevalence of mental disorder symptoms among Iranian's southern adolescents.
Mental disorders may lead to several complications in adolescents' people whose compensation is very difficult and sometime impossible. They are prone to emotional problems. Therefore, knowing prevalence of diseases and valid statistical technique is necessary to plan for prevention and control of diseases. In this cross-sectional study; direct, synthetic, and post-stratified estimation as small area methods were used to compute mental disorder symptoms (MDS) prevalence with county-level reference among adolescents in south of Iran. We conducted Mental Health Study data (MHS) conducted in Bushehr Province, southern Iran in 2005 for individual-level classification of MDS (n=2584). Students were in grade 9, 10 and 11, and enrolled with complete satisfaction. The synthetic method was superior to the direct and post-stratified technique with respect to discrepancy statistics such as MSE and width 95% confidence interval (MSEs(synthetic)≈0.001, MSEs(post-stratified)≈0.010, MSEs(direct)≈0.100). In addition, the width range of 95% confidence intervals for all county estimates was 9.7% to 65.3% based on in direct methods. Besides, the width range of 95% confidence intervals for all county estimates under post-stratified and synthetic method was 16.7% to 62.2% and 11.8 %-25.1%, respectively. Hence, we could categorize prevalence of mental disorder symptoms in Bushehr's counties into five categories based-on synthetic methods. Maximum and minimum prevalence belongs to Geneveh (0.403) and Dashty (0.398) counties, respectively. The MHS cannot be used as a valid source of county-level mental health prevalence data and the small-area method such synthetic method should be used to estimate prevalence of mental disorder symptoms in county-level. Furthermore, the synthetic method improved MDS prevalence more than direct and post-stratified methods.Immigration reform's first hurdle: Is the border secure?
By Richard Marosi, Cindy Carcamo and Molly Hennessy-Fiske
Despite barriers, migrants are still getting across, although the flow has slowed. The debate now is whether the government can do more, and pay for it. Immigration reform's first hurdle: Is the border secure?
The border barriers rise out of the Pacific Ocean, climb craggy California peaks, streak across Arizona desert valleys and meander through cattle ranches and fields of sorghum and citrus in South Texas.
Despite barriers, migrants are still getting across, although the flow has slowed.The debate now is whether the government can do more, and pay for it.Immigration reform's first hurdle:
Is the border secure?
From top to bottom: A Minutemen member with his dog at the border in Campo, Calif.; a stretch of fence in Otay Mountain, Calif.; a U.S. Border Patrol agent follows a vehicle barrier in Sasabe, Ariz. (Don Bartletti/Los Angeles Times)
The border barriers rise out of the Pacific Ocean, climb craggy California peaks, streak across Arizona desert valleys and meander through cattle ranches and fields of sorghum and citrus in South Texas.
But migrants still get across, by seeking out the one road or one mountain range or one desert trail beyond the reach of the U.S. Border Patrol.
Scenes like these form the bedrock of the immigration reform debate in Washington. The Obama administration backs a pathway to citizenship for more than 11 million illegal immigrants, and a bipartisan group of U.S. senators is working on legislation to make it happen. But first, the eight senators have agreed, the border must be certified as secure.
Memories are still fresh of the reforms of 1986, which led to citizenship for 3 million undocumented immigrants but did not strengthen the Mexican border. Millions of migrants poured through in the ensuing years, making a mockery of claims that the immigration problem had been solved.
Failure now to agree on the definition of a secure border, and on how much money to spend to achieve it, would probably kill the current reform movement.
Obama administration officials claim the frontier is more secure than ever, benefiting from the billions of taxpayer dollars spent on border defenses. There are 18,500 U.S. Border Patrol agents on the U.S.-Mexico border now, compared with 3,222 in 1986. Barriers have been built along nearly 700 miles. In 1986, most of the frontier was wide open.
Arrests of migrants have hovered around 350,000 per year recently, the lowest level since the 1970s. Falling crime rates in border communities make them some of the safest in the country. Authorities have regained control of once-trampled areas, opening the way for new subdivisions, shopping centers and industrial parks.
"We have gone above and beyond what was requested by the very Republicans who said they supported broader reform as long as we got serious about enforcement," said President Obama during a trip to the border at El Paso in 2011. "All the stuff they asked for, we've done."
But critics consider some recent gains illusory. Migrant flows have receded overall because of the lack of jobs in the U.S. The true test will come when the economy improves, they say.
Some current and former border officials doubt defenses will hold completely, especially because certain areas remain porous. They say more enforcement measures are needed. One of the critics' oft-cited facts: There are fewer agents patrolling a nearly 2,000-mile border than there are cops, about 34,500, in New York City.
Border security is still a work in progress, said Ronald Colburn, a former chief U.S. Border Patrol agent. "We're not there yet. The border is still a high-risk situation," said Colburn, who oversaw some of the fence construction. Migrant arrests, which topped 120,000 in Arizona alone last year, he said, remain at worrisome levels.
Homeland Security officials express frustration at what they consider unrealistic expectations. Because accurate measurement of migrant traffic has always been elusive (how can migrants be counted if they're not caught?), security levels will always be open to interpretation.
Down along the endlessly varied terrain and ever-shifting flows of migrant traffic across the 1,954-mile U.S.-Mexico border, the picture is decidedly mixed, giving ammunition to both sides to make their arguments. Keep reading »
When the federal government moved to control the border in the 1990s, it focused on America's frontier towns and cities. In enforcement parlance, such communities are called melt zones,
|
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] |
by advocate Sugriva Dubey has sought that wholesale traders of rice, pulses and fruits be raided, and samples be tested for adulteration to protect the common man.
It said that plastic rice when ingested along with the real one is not digested and leads to serious gastric ailments.
“Due to globalisation, rice in large quantities is being imported from China and even pulses are being imported from different countries, but no quality test is conducted,” the application said.
It alleged that the rice imported from China includes “plastic rice” and ordinary persons cannot differentiate between it and the real rice.
The plea also alleged that fruits like mangoes are being ripened artificially by using calcium carbide or other chemicals. — PTIHow crazy is it that Brock Lesnar is main eventing one of the biggest cards in MMA history, and just a few months ago his return to the UFC wasn’t even fathomable? Fate has her own story to write and clearly is not concerned with Jones reclaiming the title he never lost. At least not now.
Cormier says he would still like to fight at UFC 200 if they can find an opponent. Anyone want a shot at the arguably number two pound-for-pound fighter on the planet and the UFC light heavyweight title on two days notice?
Daniel Cormier says he's even willing to go up to like 220 or 225 to fight at #UFC200Chad Haefele – “I’ve spent a lot of time lately thinking (and writing) about eBooks, usually taking a pretty negative slant toward existing eBook publishers and vendors. DRM, distribution models, even publication timelines – much of it is a huge mess. But I don’t want to seem too negative – I still think eBooks as a concept hold massive promise. It’s just many of the current implementations that’re flawed. So who’s doing it right? Here’s a handful of companies and products which I think are on the right track”Upregulation of MicroRNA-19b predicts good prognosis in patients with hepatocellular carcinoma presenting with vascular invasion or multifocal disease
AbstractBackground
After surgical resection of hepatocellular carcinoma (HCC), recurrence is common, especially in patients presenting with vascular invasion or multifocal disease after curative surgery. Consequently, we examined the expression pattern and prognostic value of miR-19b in samples from these patients.
Methods
We performed a miRNA microarray to detect differential expression of microRNAs (miRNAs) in 5 paired samples of HCC and non-tumoral adjacent liver tissue and a quantitative real-time polymerase chain reaction (PCR) analysis to validate the results in 81 paired samples of HCC and adjacent non-tumoral liver tissues. We examined the associations of miR-19b expression with clinicopathological parameters and survival. MiR-19b was knocked down in Hep3B and an mRNA microarray was performed to detect the affected genes.
Results
In both the miRNA microarray and real-time PCR, miR-19b was significantly overexpressed in the HCC tumor compared with adjacent non-tumor liver tissues (P
AbstractGenetic or nutritional deficiencies in homocysteine (Hcy) metabolism lead to hyperhomocysteinemia (HHcy) and cause endothelial dysfunction, a hallmark of atherosclerosis. In addition to Hcy, related metabolites accumulate in HHcy but their role in endothelial dysfunction is unknown. Here, we examine how Hcy-thiolactone, N-Hcy-protein, and Hcy affect gene expression and molecular pathways in human umbilical vein endothelial cells. We used microarray technology, real-time quantitative polymerase chain reaction, and bioinformatic analysis with PANTHER, DAVID, and Ingenuity Pathway Analysis (IPA) resources. We identified 47, 113, and 30 mRNAs regulated by N-Hcy-protein, Hcy-thiolactone, and Hcy, respectively, and found that each metabolite induced a unique pattern of gene expression. Top molecular pathways affected by Hcy-thiolactone were chromatin organization, one-carbon metabolism, and lipid-related processes [−log(P value) = 20–31]. Top pathways affected by N-Hcy-protein and Hcy were blood coagulation, sulfur amino acid metabolism, and lipid metabolism [−log(P value)] = 4–11; also affected by Hcy-thiolactone, [−log(P value) = 8–14]. Top disease related to Hcy-thiolactone, N-Hcy-protein, and Hcy was ‘atherosclerosis, coronary heart disease’ [−log(P value) = 9–16]. Top-scored biological networks affected by Hcy-thiolactone (score = 34–40) were cardiovascular disease and function; those affected by N-Hcy-protein (score = 24–35) were ‘small molecule biochemistry, neurological disease,’ and ‘cardiovascular system development and function’; and those affected by Hcy (score = 25–37) were ‘amino acid metabolism, lipid metabolism,’ ‘cellular movement, and cardiovascular and nervous system development and function.’ These results indicate that each Hcy metabolite uniquely modulates gene expression in pathways important for vascular homeostasis and identify new genes and pathways that are linked to HHcy-induced endothelial dysfunction and vascular disease.
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✔本篇論文使用華聯產品：Human OneArray
Oncoscience. doi:10.18632/oncoscience.285.
In silico and experimental analyses predict the therapeutic value of an EZH2 inhibitor GSK343 against hepatocellular carcinoma through the induction of metallothionein genes
AbstractThere are currently no effective molecular targeted therapies for hepatocellular carcinoma (HCC), the third leading cause of cancer-related death worldwide. Enhancer of zeste homolog 2 (EZH2), a histone H3 lysine 27 (H3K27)-specific methyltransferase, has been emerged as novel anticancer target. Our previous study has demonstrated that GSK343, an S-adenosyl-L-methionine (SAM)-competitive inhibitor of EZH2, induces autophagy and enhances drug sensitivity in cancer cells including HCC. In this study, an in silico study was performed and found that EZH2 was overexpressed in cancerous tissues of HCC patients at both gene and protein levels. Microarray analysis and in vitro experiments indicated that the anti-HCC activity of GSK343 was associated with the induction of metallothionein (MT) genes. In addition, the negative association of EZH2 and MT1/MT2A genes in cancer cell lines and tissues was found in public gene expression database. Taken together, our findings suggest that EZH2 inhibitors could be a good therapeutic option for HCC, and induction of MT genes was associated with the anti-HCC activity of EZH2 inhibitors.
AbstractThe inhibition of β-catenin/LEF-1 signaling is an emerging strategy in cancer therapy. However, clinical targeted treatment of the β-catenin/LEF-1 complex remains relatively ineffective. Therefore, development of specific molecular targets is a key approach for identifying new cancer therapeutics. Thus, we attempted to synthesize a peptide (TAT-NLS-BLBD-6) that could interfere with the interaction of β-catenin and LEF-1 at nuclei in human breast cancer cells. TAT-NLS-BLBD-6 directly interacted with β-catenin and inhibited breast cancer cell growth, invasion, migration, and colony formation as well as increased arrest of sub-G1 phase and apoptosis; it also suppressed breast tumor growth in nude mouse and zebrafish xenotransplantation models, showed no signs of toxicity, and did not affect body weight. Furthermore, the human global gene expression profiles and Ingenuity Pathway Analysis software showed that the TAT-NLS-BLBD-6 downstream target genes were associated with the HER-2 and IL-9 signaling pathways. TAT-NLS-BLBD-6 commonly down-regulated 27 candidate genes in MCF-7 and MDA-MB-231 cells, which are concurrent with Wnt downstream target genes in human breast cancer. Our study suggests that TAT-NLS-BLBD-6 is a promising drug candidate for the development of effective therapeutics specific for Wnt/β-catenin signaling inhibition.I first discovered this game on Reddit, as an ad. Incredibly addictive, difficult as hell once you get to the higher levels, and impossible to put down!TOKYO (Reuters) - Former Nissan Motor Co Representative Director Greg Kelly has been released on bail after more than a month in detention on financial-misconduct charges, as a Tokyo court rejected prosecutors’ request to keep the American executive in custody.
Media crews are seen on step ladders in front of the Tokyo Detention Center, where Nissan's arrested chairman Carlos Ghosn and a former Nissan executive Greg Kelly are being held, in Tokyo, Japan December 25, 2018. REUTERS/Kim Kyung-Hoon
Kelly and Carlos Ghosn, the automaker’s ousted chairman, were detained upon arrival in Japan on Nov. 19 on suspicion of understating Ghosn’s income in financial statements for several years.
The arrests jolted the global car industry and strained Nissan’s alliance with French car maker Renault SA. Ghosn remains in custody.
A crowd of Japanese and international reporters and camera crews had gathered since Tuesday morning waiting for Kelly’s release. He left the Tokyo Detention Center with his lawyer, Yoichi Kitamura, by taxi at around 10:45 p.m. (1345 GMT), a Reuters witness said.
Kelly said in a statement that he had not falsified any documents and looked forward to restoring his honor in court, adding that he wanted to return to his family as soon as possible,
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the
majority who don't... I'm just curious if this dichotomy becomes obvious
outside of the interview... like on the job? Do you notice a difference when
working with a google engineer vs. someone who probably can't ever get into
google. It's a complicated question with a complicated answer. I'm not really
looking for some humble answer telling me that google engineers aren't that
much different from other engineers when the interview essentially disproves
this statement by filtering out everyone except for a certain type of person.
I want an honest and candid answer.
~~~
opportune
Ok sure I’ll give you an honest and candid answer. It’s basically analogous to
top schools. Yes the average engineer at Google is going to be better than the
average engineer at some random company because google generally has a higher
hiring bar. Similarly your average student at Harvard is going to be a better
student than your average student at Random State University.
As a result you will on average learn more than at most other companies. Of
course there are trading firms, quant hedge funds, and a few other big tech
companies with even higher hiring bars where you will learn more. And some of
the things you learn, anywhere, while very useful to getting stuff done at
where you work, will not be readily transferable elsewhere.
But large companies as I’ve said before are basically all the same. The people
you interact with are a vanishingly small subset of the entire company so it
doesn’t even really make sense to speak in terms of what it’s like at the
entire company.
The interviewing filter mostly does one thing which is that it biases the
engineers at google to be generally good at solving data structures and
algorithms. This, by the way, is a skill that can be taught — and even though
it might roughly approximate engineering ability it doesn’t map directly.
~~~
crimsonalucard
Thanks for being candid, is this inline with your experience? Have you worked
at a smaller company and google as well? Your logic is really sound but I'm
also asking this question for the purposes of gathering anecdotal experiences
as well.
Your answer is great, btw, I just noted that you used the word "average" over
a personal example so I wanted to get an idea of where you're coming from.
~~~
opportune
Yeah I’ve worked at G, other big companies and smaller places. My own
anecdotes roughly fit my “average” explanations.
Ever Knight SNAPP Review
(SNAPP Reviews aren’t really a full fledged game review as much as they are just a way for us to give you a quick “heads-up” on whether a certain game is good or not. It usually means that we haven’t finished the game yet, but have played a good enough chunk to know whether it’s worth your time/money or not.)
So, just yesterday a game released on the App Store by the name, Ever Knight (Kyle Barrett). I’ve been finding myself going back to it time and time again, so I figured I’d give it a quick SNAPP Review to let you know what it’s all about.
Ever Knight is described as “an endless arcade style hack & slasher with simple controls and fast paced action”. Personally, I feel that it’s more in the Crossy Road genre (is that considered a genre now?) than a hack & slash game, but that doesn’t lessen it in any way.
Ever Knight is endless, so the ultimate goal is to get as far as you can. The farther you get, the higher your score (of course). The controls are set up pretty much like most Crossy Road style games. You swipe forward or tap on the screen to move forward and swipe left, right, down to move your character in those directions. I’ve found myself just swiping to go forward instead of tapping so I don’t get myself confused. It’s just easier to swipe the way you are wanting to go.
There are no obstacles to worry about in Ever Knight. What you are up against is a never ending army of enemies just waiting to destroy you. You auto-attack as soon as you get close to anyone, so you are kind of swiping your way through everyone to go forward. There’s no room for error either. All it takes is one hit from an enemy and it’s game over. If you are too slow, you’re going to get killed. There’s definitely a sense of urgency in this game. Fallen enemies will leave coins sometimes for you to collect. You can use these coins to buy new weapons and armor. What’s cool is that each of the 37 pieces of equipment has a different effect that will help you throughout your runs.
I’ve been having a lot fun with Ever Knight so far. It’s not perfect though. The game can seem very “grindy” at times. Equipment feels a little too expensive compared to how many coins you get per run. I also don’t like having to go back to pick up coins after you kill an enemy. It feels like you end up missing out on a lot coins when you’re just trying to survive. It’s still not enough not to recommend this game. For 99 cents, it’s definitely worth the purchase.It's going to end well for the Warriors, at least in terms of the regular season. They play 16 of their final 22 games at home, including a seven-game, soul-reviving homestand March 4-15. From that point until the finish of the season April 17, they have exactly two road games that appear difficult: at Houston and San Antonio in the third week of March.
Whatever ails the Warriors in the second half - and who knows, they could be hovering around that eighth and final playoff spot by the conclusion of this month - that ongoing Oracle feast will make things right.
As for the playoffs themselves, no great optimism here. Too much was revealed during the five-game losing streak that wrapped up the first half. Fatigue may have been a factor, but more to the point: The Warriors are not a good defensive team, and don't be fooled into believing that they are.
They did a pretty good impersonation for weeks at a time, and that's a credit to coach Mark Jacksonand the players' determination. Defense is built on hustle and desire, but only partly so; skill is the most vital component. If the Warriors are going to finish games with Stephen Curry, Klay Thompsonand David Leeon the floor, that's three players who may care about defense deeply, but fall terribly short of the league's lofty standard. (There isn't a backcourt in the league that doesn't see "Golden State" as a precious gift on the calendar.)
As far as Andrew Bogut's prospects in the second half, the crisis calls up an old Charlie Finleyline (certainly not his invention): "Big hat, no cattle." Bogut is a man of immense physical gifts, but why would anyone believe he'll be at full capacity at any point this season? He's either not playing at all, or losing steam by the fourth quarter.
At least Bogut is seeing things clearly. He basically called out the entire team after Tuesday night's home loss to Houston, saying the Warriors' quickness and weak-side help were severely lacking on defense. Come playoff time, when every opponent poses a massive threat, that's a weakness that cannot be disguised.
Slowtime
No, I don't count the Lakers (at the Staples Center on April 12) as a road game that appears difficult. The Lakers are pathetic. They're old, they're injured, they have no palpable leadership, they don't much care for each other, and they've lost L.A. to the Clippers... At first glance, the Warriors' new sleeved uniforms aren't all that offensive. The pinstriped shorts (who came up with that?) can easily be replaced. Then again, they were modeled by Harrison Barnes, a man who would look good wearing oil-soaked rags from an abandoned warehouse. "I'd love to see Oliver Miller(the rotund big man of yore) in one of those," cracked Tom Tolbert on KNBR, and that goes for (A) any player who would rather not take the court in a tight-fitting jersey or (B) any great shooter who wants no part of sleeves. "This wouldn't have worked for me," said Dennis Scott, one of the all-time marksmen, on NBA TV. "I want to hear what Curry and Thompson say about 'em" after a test in actual games... No wrestling in the Olympics? Sounds a bit like the banishment of the Cal baseball program. Something that will eventually be overturned, on the basis of common sense. How can you ditch a sport that made its first appearance at the ancient Olympic Games in 708 B.C.? Don't rule out a shady deal or two, either. That's undoubtedly at the root of this mess. But any group as corrupt as the International Olympic Committee can just as easily be swayed another 180 degrees.
If Hideki Okajimagets a place in the A's bullpen, it will definitely be "a very big deal," as pitching coach Curt Youngsaid. Okajima might still be the man who had three superb years in the Boston pressure cooker (2007-09) and has given up just 221 hits in 246 1/3 major
|
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] |
then roll over to the next payment date until pay-out is reachedCastelsantangelo sul Nera
Castelsantangelo sul Nera is a comune (municipality) in the Province of Macerata in the Italian region of Marche, located about southwest of Ancona and about southwest of Macerata. The source of the Nera River is located in the communal territory.
References
Category:Cities and towns in the MarcheInternational Games System Co., Ltd. (IGS)
"In collaboration with Nextlink, we were provided many professional advices from the architecture design, cost optimization, and professional consultant services. Nextlink Managed Services Team always supports us to solve problems during incident event happened, and then, we can focus on operating our core business, which is creating an awesome game for gamers.
-- Arcade Game Division Assistant Manager
Paddy Yang
Company Profile
IGS was founded in 1991, they developed its own brand and technologies at beginning, and it broken the Japanese game manufacturers long-term monopoly situation, which became a famous brand in gaming industry in Asia. In 1996, they completed the 2D game research and development; in 1998, they had a largest R&D team in gaming industry in Chinese region; during 2000-2003, they focused on cross-platform development, and they made a major breakthrough in PC game, machine games, PGM, online game, touch screen game, TSG and Atomiswave. From 2004, IGS decided to go to international marketing. In 2006, IGS listed on the market, and three of their goals are making video game console emulator in no.1 market share, becoming the best online game content provider, building the best R&D game team, all of these goals made IGS an International and world-class enterprise.
The Challenge
30 years ago, IGS started their business in manufacturing printed circuit boards and game machine boards,hardware. After establishing the company Few years later, they began to research and to develop in game of chance, mahjong, and create the first Chinese self-made fighting game; 20 years ago, IGS has already accessed to China market, where they promoted 3D, rhythm and dance game machines; 10 years ago, IGS has begun to develop online games; in the recent 5 years, they start to invest mobile game research and development, and then they accessed to the European and American markets, such as the United States, Italy… in order to become globalized, IGS started to find flexibility solutions to meet the worldwide market needs.
In the past, IGS used IDC entity hosting services to online game and app game. However, online games required relatively large data processing and performance for the players, and app games do not need so much resources, so they want the cost can be more inelastic; in addition, the traditional IDC implementation process is complex and lack of flexibility. To find a flexible and immediately-responded service, IGS considered cloud service as the primary choice.
The Solution
Before adopting cloud services, IGS also evaluated the cloud services provided by different vendors. However, some of the manufacturers just give IGS the lower control capacity, and their services need professional staff to maintain.In the end, IGS chose Amazon Web Services. There are the following considerations:
AWS is the leading cloud service provider, it has more support services.
AWS is more transparent in price and resource than other cloud service providers.Recently Michael Keenan, the Australian Minister for Justice introduced a bill to include digital currencies in the Anti-Money Laundering and Counter-Terrorism Financing Act.
The motivation for this bill is because of the risk that criminals will use digital currencies to escape detection. While the bill may help in catching criminals who use Bitcoin, it’s not needed. See: Bitcoin Transactions Aren’t as Anonymous as Everyone Hoped.
However, this bill will mostly serve to erode Australians’ civil rights and make it harder and more expensive for us to use digital currencies.
We have the right to not identify
According to the Office of the Australian Information Commissioner:
As an individual, the Privacy Act gives you greater control over the way that your personal information is handled. The Privacy Act allows you to: know why your personal information is being collected, how it will be used and who it will be disclosed to
have the option of not identifying yourself, or of using a pseudonym in certain circumstances
Who is affected?
People who have family or friends in high risk countries
Anti-money laundering laws disqualify entire nations from sending/receiving money. Digital currencies like Bitcoin has provided an alternative for people from high risk countries to receive support from their families in Australia, but soon they can also be denied Bitcoin services in Australia.
Local bitcoins traders across Australia, who help people buy and sell Bitcoin will face 2 years prison time for a first offence and up to 7 years prison time maxium. Given this is already happening in the US, I wouldn’t be surprised to see Australian traders next.
Bitcoin ATM operators — granted there are not many; possibly under 20 in Australia according to coinatmradar.com. Many of them will not be able to fulfil the requirements of identifying customers and will be hit with high compliance costs, further increasing the price to buy digital currencies or causing them to shut down.
The general population of Australia will be slower in adopting digital currencies. Other small countries like Jamaica are already actively building cryptocurrency awareness because they can see the economic opportunity it presents.
The bill is incompatible with civil and political rights
The proposed bill claims that it is compatible with the human rights and freedoms recognised or declared in the international instruments listed in section 3 of the Human Rights (Parliamentary Scrutiny) Act 2011.
Section (1) of this act includes:
human rights means the rights and freedoms recognised or declared by the following international instruments:
(c ) the International Covenant on Civil and Political Rights done at New York on 16 December 1966 ([1980] ATS 23);
In the International Covenant on Civil and Political Rights, Article 2 Section 2:
The States Parties to the present Covenant undertake to guarantee that the rights enunciated in the present Covenant will be exercised without discrimination of any kind as to race, colour, sex, language, religion, political or other opinion, national or social origin, property, birth or other status.
What can you do?
Share this article and if you have time, contact your local MP or media outlet.#include "instructions/p_init.hpp"
namespace rubinius {
namespace interpreter {
intptr_t p_init(STATE, CallFrame* call_frame, intptr_t const opcodes[]) {
const intptr_t subject = argument(0);
const intptr_t captures = argument(1);
instructions::p_init(state, call_frame, subject, captures);
call_frame->next_ip(instructions::data_p_init.width);
return ((instructions::Instruction)opcodes[call_frame->ip()])(state, call_frame, opcodes);
}
}
}
According to a Yemeni journalist, the U.S. company Blackwater sends its staff of mercenaries in Yemen under-cover of the Colombian military, to commit crimes.
Abdullah bin Amer, Yemeni journalist revealed [in a report on the website “Yemen Press“] that the American criminal society called ‘Blackwater’, whose license in Iraq was revoked by Baghdad for committing crimes, sent [on request by Saudi Arabia] military forces in Yemen.
He said that the information, published according to which the military were dispatched to Yemen militaries of Colombian nationality, were wrong.
“They are nothing but mercenaries of the U.S. company Blackwater who are active in Colombia and most of its elements are mercenaries from countries of South America”, said the Yemeni journalist.
He said that, suggesting that these soldiers were of Colombian forces, was to hide the truth from the public & the media because the American Blackwater [company of mercenaries] has a very bad reputation.
Globalization of trade and central banking has propelled private corporations to positions of power and control never before seen in human history. Under advanced capitalism, the structural demands for a return on investment require an unending expansion of centralized capital in the hands of fewer and fewer people. The financial center of global capitalism is so highly concentrated that less than a few thousand people dominate and control $100 trillion of wealth.
The few thousand people controlling global capital amounts to less than 0.0001 percent of the world’s population. They are the transnational capitalist class (TCC), who, as the capitalist elite of the world, dominate nation-states through international trade agreements and transnational state organizations such as the World Bank, the Bank for International Settlements, and the International Monetary Fund.
The TCC communicates their policy requirements through global networks such as the G-7 and G-20, and various nongovernmental policy organizations such as the World Economic Forum, the Trilateral Commission, and the Bilderberger Group. The TCC represents the interests of hundreds of thousands of millionaires and billionaires who comprise the richest people in the top 1 percent of the world’s wealth hierarchy.
The TCC are keenly aware of both their elite status and their increasing vulnerabilities to democracy movements and to unrest from below. The military empire dominated by
|
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\] Let $\ell\in\Aa(\C)$ be admissible and let $\{A_s\}$, $0\le s\le 1$ be a curve in $\Aa_{\ell}(X)$. Then the spectral flow $\operatorname{sf}_{\ell}\{A_s\}$ is well defined, and the following holds:
1. [**Catenation.**]{} Assume $t\in [0,1]$. Then we have $$\label{e:sf-catenation}
\operatorname{sf}_{\ell}\{A_s;0\le s\le t\}+\operatorname{sf}_{\ell}\{A_s;t\le s\le
1\}=\operatorname{sf}_{\ell}\{A_s;0\le s\le 1\}.$$
2. [**Homotopy invariance.**]{} Let $A(s,t)$, $(s,t)\in[0,1]\times[0,1]$ be a continuous family in $\Aa_{\ell}(X)$. Then we have $$\label{e:sf-homotopy}
\operatorname{sf}_{\ell}\{A(s,t);(s,t)\in\partial([0,1]\times[0,1])\}=0.$$
3. [**Endpoint dependence for Riesz continuity.**]{} Let $\Bb^{\operatorname{sa}}(X)$, respectively $\Cc^{\operatorname{sa}}(X)$ denote the spaces of bounded, respectively closed self-adjoint operators in $X$. Let $$\begin{matrix}
R&:&\Cc^{\operatorname{sa}}&\to&\Bb^{\operatorname{sa}}(X)\\
\ &\, & A&\mapsto & A(A^2+I)^{-\frac{1}{2}}
\end{matrix}$$ denote the [*Riesz transformation*]{}. Let $A_s\in\Cc^{\operatorname{sa}}(X)$ for $s\in [0,1]$. Assume that $\{R(A_s)\}$, $0\le s\le 1$ is a continuous family. If $m^-(A_0)<+\infty$, then $m^-(A_1)<+\infty$ and we have $$\label{sf-general}
\operatorname{sf}\{A_s\}=m^-(A_0)-m^-(A_1).$$
4. [**Product.**]{} Let $\{P_s\}$ be a curve of projections on $X$ such that $P_sA_s\subset A_sP_s$ for all $s\in[0,1]$. Set $Q_s=I-P_s$. Then we have $P_sA_sP_s\in \Aa_{\ell}(\operatorname{im}P_s)\<
\Cc(\operatorname{im}P_s)$, $Q_sA_sQ_s\in \Aa_{\ell}(\operatorname{im}Q_s)\<
\Cc(\operatorname{im}Q_s)$, and $$\label{sf-product}
\operatorname{sf}_{\ell}\{A_s\}=\operatorname{sf}_{\ell}\{P_sA_sP_s\}+\operatorname{sf}_{\ell}\{Q_sA_sQ_s\}.$$
5. [**Bound.**]{} For $A\in\Aa_{\ell}(X)$, there exists a neighborhood $\Nn$ of $A$ in $\Cc(X)$ such that $\Nn\subset\Aa_{\ell}(X)$, and for curves $\{A_s\}$ in $\Nn$ with endpoints $A_0=:A$ and $A_1=:B$, the [*relative Morse index*]{} $I_{\ell}(A,B):= -\operatorname{sf}_{\ell}\{A_s,0 \, ; \, \le s\le 1\}$ is well defined and satisfies $$\label{sf-bound}
0\le I_{\ell}(A,B)\le\nu_{h,\ell}(A)-\nu_{h,\ell}(B).$$
6. [**Reverse orientation.**]{} Let $\hat {\ell}$ denote the curve $\ell$ with opposite co-orientation. Then we have $$\label{e:sf-reverse}
\operatorname{sf}_{\ell}\{A_s\}+\operatorname{sf}_{\hat
{\ell}}\{A_s\}=\nu_{h,\ell}(A_1)-\nu_{h,\ell}(A_0).$$
7. [**Zero.**]{} Suppose that $\nu_{h,\ell}(A_s)$ is constant for $s\in [0,1]$. Then $\operatorname{sf}_{\ell}\{A_s\}=0$.
8. [**Invariance.**]{} Let $\{T_s\}_{s\in[0,1]}$ be a curve of bounded invertible operators. Then we have $$\label{sf-invariance}\operatorname{sf}_{\ell}\{T_s^{-1}A_sT_s\}=\operatorname{sf}_{\ell}\{A_s\}.$$
Now we give a method of calculating the spectral flow of differentiable curves, inspired among others by J.J. Duistermaat [@Du76] and J. Robbin and D. Salamon [@RoSa93].
\[d:crossing\] Let $\ell\in\Aa(\C)$ be admissible and $\{A_s\}_{s\in[0,1]}$ be a curve in $\Aa_{\ell}(X)$.
1. A [*crossing*]{} for $A_s$ is a number $t\in [0,1]$ such that $\nu_{h,\ell}(A_t)\ne 0$.
2. Set $P_s=P^0_{\ell}{A_s}$. A crossing $t$ is called [*regular*]{} if $\operatorname{dom}(A_s)=D$ fixed for $s$ near $t$, $A_sx$ is differentiable at $s=t$ for all $x\in D$, and $P_t\dot{A_t}P_t$ is [*hyperbolic*]{}, i.e. $\nu_{h,\ell}(P_t\dot{A_t}P_t)=0$, where $\dot{A_s} $ is the unbounded operator with domain $D$ defined by $$\dot{A_s}x=\frac{d}{ds}A_sx$$ for all $x\in D$.
3. A crossing $t$ is called [*simple*]{} if it is regular and $\nu_{h,\ell}(A_t)=1$.
\[p:cal-sf\] Let $X$ be a Banach space and $\ell=\sqrt{-1}(-\epsilon,\epsilon)$ ($\epsilon>0$) with co-orientation from left to right. Let $A_s$, $-\epsilon\le s\le \epsilon$ ($\epsilon>0$), be a curve in $\Aa_{\ell}(X)$. Suppose that $0$ is a regular crossing of $A_s$. Set $P=P^0_{\ell}(A_0)$, $A=A_0$ and $B=\dot A_s|_{s=0}$. Assume that $$\label{e:cal-sf-com}
P(AB-BA)P=0.$$ Then there is a $\delta\in(0,\epsilon)$ such that $\nu_{h,\ell}(A_s)=0$ for all $s\in[-\delta,0)\cup (0,\delta]$ and $$\begin{aligned}
& &\label{e:cal-sf1}\operatorname{sf}_{\ell}\{A_s ; 0\le s\le\delta\}=-m^{-}(PBP),\\
& &\label{e:cal-sf2}\operatorname{sf}_{\ell}\{A_s ; -\delta\le s\le
0\}=m^+(PBP).\end{aligned}$$ Here we denote by $m^+(PBP)$ $($$m^-(PBP)$$)$ the total algebraic multiplicity of eigenvalues of $PBP$ with positive $($negative$)$ imaginary part respectively.
Symplectic functional analysis and Maslov index {#ss:symplectic}
-----------------------------------------------
A main feature of symplectic analysis is the study of the [*Maslov index*]{}. It is an intersection index between a path of Lagrangian subspaces with the [*Maslov cycle*]{}, or, more generally, with another path of Lagrangian subspaces. The Maslov index assigns an integer to each continuous path of Fredholm pairs of Lagrangian subspaces of a fixed Hilbert space with continuously varying symplectic structures.
Firstly we define symplectic Hilbert spaces and Lagrangian subspaces.
\[d:algebraic\_symplectic\_space\] Let $H$ be a complex vector space. A mapping $$\w:H\times H\too \C$$ is called a (weak) [*symplectic form*]{} on $H$, if it is sesquilinear, skew-hermitian, and non-degenerate, i.e.,
\(i) $\w(x,y)$ is linear in $x$ and conjugate linear in $y$;
\(ii) $\w(y,x)=-\ol{\w(y,x)}$;
\(iii) $H^{\w} := \{x\in H \mid \w(x,y)=0\text{ for all $y\in
H$}\} = \{0\}$.
Then we call $(H,\w)$ a [*complex symplectic vector space*]{}.
\[d:lagrangian\] Let $(H,\w)$ be a complex symplectic vector
|
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of exudates allows the detection of serum, intracellular and membrane-associated proteins, and these findings may shed light on the pathological action of SVMPs from a broader perspective. Similar quantitative patterns of plasma-derived proteins were detected in exudates from mice injected with the three toxins. This seems logical, as the presence of these proteins is largely a consequence of overt microvessel damage by the action of these enzymes. Hence, extravasation of blood results in similar amounts of serum plasma proteins, and of hemoglobin as well. An exception to this general trend was observed with hydrolysis products of fibrinogen, which were in higher amounts in exudates from animals injected with the PI SVMP. Since this enzyme has fibrinolytic activity \[[@pntd.0003731.ref030]\] and was injected in a higher dose than the other two SVMPs, this may have resulted in hydrolysis of the fibrin formed as a consequence of extravasation and clot formation.
When the amounts of intracellular proteins were compared in exudates, it was of interest that the PI SVMP, and also the PII SVMP, induced a higher amount of keratins than PIII SVMP. It is suggested that this reflects the ability of the former SVMPs to induce dermonecrosis and blistering which has been shown to be the case with this particular PI SVMP \[[@pntd.0003731.ref040]\], but has not been previously explored for the PII SVMP. It is noteworthy that the dermotoxic action of the PII SVMP occurs when injected at a very low dose. On the other hand, there were several other intracellular proteins whose amounts were higher in exudates collected from mice injected with PII and PIII SVMPs. This suggests that these enzymes induce a higher cytotoxic activity in various cell types in the tissue. The three SVMPs induced a similar extent of skeletal muscle damage, as revealed by the similar amounts of the cytosolic muscle cell marker creatine kinase in exudates; it has been suggested that hemorrhagic SVMPs induce myotoxicity as a consequence of tissue ischemia \[[@pntd.0003731.ref041]\]. The higher amounts of several intracellular markers in exudates collected from PII and PIII SVMPs-injected mice may be due to the targeting of these enzymes, through exosites present in the additional domains, to sites in the plasma membrane or in the vicinity of cells, a hypothesis that remains to be investigated.
In conclusion, our findings demonstrate that PII and PIII hemorrhagic SVMPs co-localize with type IV collagen in capillaries, PCVs and arterioles, whereas PI SVMP presents a more widespread localization in the tissue. This difference in tissue localization is likely to be one of the main reasons behind the higher hemorrhagic activity characteristic of PII and PIII SVMPs, as compared to enzymes of the PI class. Furthermore, immunochemical results support the hypothesis that hydrolysis of type IV collagen is likely to be a key event in SVMP-induced microvessel damage and destabilization leading to hemorrhage.
Supporting Information {#sec020}
======================
###### List of all proteins identified in wound exudates collected from mice injected with PI (*B. asper*), PII (*B. lateralis*) and PIII (*C. simus*) SVMPs.
(PDF)
######
Click here for additional data file.
###### Serum proteins identified in wound exudates collected from mice injected with PI, PII or PIII SVMPs.
(PDF)
######
Click here for additional data file.
###### Coagulation factors identified in wound exudates collected from mice injected with PI, PII or PIII SVMPs.
(PDF)
######
Click here for additional data file.
###### Serum proteinase inhibitors identified in wound exudates collected from mice injected with PI, PII or PIII SVMPs.
(PDF)
######
Click here for additional data file.
###### Intracellular proteins identified in wound exudates collected from mice injected with PI, PII or PIII SVMPs.
(PDF)
######
Click here for additional data file.
###### Keratins identified in wound exudates collected from mice injected with PI, PII or PIII SVMPs.
(PDF)
######
Click here for additional data file.
###### Membrane proteins identified in wound exudates collected from mice injected with PI, PII or PIII SVMPs.
(PDF)
######
Click here for additional data file.
Thanks are due to Bruno Lomonte for performing some proteomic analysis of SVMPs. This work was performed in partial fulfillment of the requirements for the PhD degree for Cristina Herrera at Universidad de Costa Rica.
[^1]: The authors have declared that no competing interests exist.
[^2]: Conceived and designed the experiments: CH TE MBV AR JJC LS SN JMG JWF. Performed the experiments: CH TE MBV AR DM JKAM JJC LS. Analyzed the data: CH TE MBV AR DM JKAM JJC LS SN JMG JWF. Contributed reagents/materials/analysis tools: TE MBV AR JJC SN JMG JWF. Wrote the paper: CH TE MBV AR JJC LS SN JMG JWF.
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] |
^{2}}{r_{b}^{2}}} \right)$$
where *P* is the laser power, *r* ~*b*~ is the laser beam spot radius, *r* is the distance from the beam center, and *α* is absorptivity coefficient. The average laser energy flux $E_{s}{(\text{W}/\text{mm}^{2})}$ can be expressed as:
$$E_{s} = \frac{1}{\pi r_{b}^{2}}\int\limits_{0}^{r_{b}}2\pi rE\left( r \right)\text{d}r = \frac{2\alpha P}{\pi r_{b}^{2}}{(1 - e^{- 2})}$$
The energy loss in the molten pool can be divided into three parts, including convective heat loss, radiation heat loss, and heat loss through evaporation \[[@CIT0025]\]. Usually, the heat loss due to convection and radiation is generally assumed to be about 10% \[[@CIT0024]\]. Previous calculations revealed that the latent heat of evaporation is relatively large, causing prominent energy loss, especially at high temperatures. The heat loss through evaporation was therefore estimated to be 10% \[[@CIT0025]\]. Therefore, the total heat loss during the SLM process was assumed to be 20%. This estimation of heat loss is of a similar level with previous work of direct laser deposition H13 tool steel, in which about 75--85% of original power reached the molten pool surface \[[@CIT0027]\]. Hence, the effective laser energy flux $E_{\text{in}}{(\text{W}/\text{mm}^{2})}$ used for melting the powders is:
$$E_{\text{in}} = E_{s} - E_{\text{loss}} = E_{s}\mspace{600mu}{(1 - 0.2)}$$
Therefore, the volumetric laser energy per unit volume $Q_{v}\,{(\text{J}/\text{mm}^{3})}$ of tungsten powders can be expressed as
$$Q_{v} = \frac{\pi r_{d}^{2}E_{\text{in}}\Delta t}{V_{m}}\mspace{600mu}$$
$$\Delta t = \frac{2r_{b}}{v}$$
where Δ*t* is the laser exposure time, *v* is the laser scan speed, *V* ~*m*~ is the effective volume of molten pool. As shown in Figure [2](#F0002){ref-type="fig"}, we simplified the profile of the molten pool as a part of sphere, and the *V* ~*m*~ can be estimated as:
$$V_{m} \cong \frac{1}{2} \times \frac{4}{3}\pi R^{3} - \frac{1}{3}\pi{(\text{R} - \text{H})}{(R^{2} + r^{2} + \text{Rr})}$$
where *r* is the effective radius of laser beam, H is the effective laser melting depth and *R* is the radius of the sphere. Normally, the width of the laser melting track on the powder is about twice as the radius of laser beam *r* ~*b*~, so we suppose *r* = 2*r* ~*b*~. Besides, for the purpose of introducing laser re-melting of the under layer, we designed the effective laser melting depth to be as thick as two layer thickness (i.e. H = 40 μm). Since, it enables a reliable connection between the layers and suppresses the balling phenomenon as balling can occur when tungsten molten pools solidify too quickly to spread out completely. Furthermore, choosing a suitable laser re-melting depth would also reduce the tendency of cracking, since re-melting can break up the oxide films and reduce the thermal stress \[[@CIT0005]\]. Consequently, *V* ~*m*~ and *Q* ~*v*~ can be rationally calculated. When $Q_{v} \geq Q_{p}{(Q_{p} = 8.595\,\text{J}/\text{mm}^{3})}$, the laser should theoretically completely melt the powders. To meet the requirement of $Q_{v} \geq Q_{p}$, the condition for linear energy $\eta \geq 0.42\,\text{J}/\text{mm}$ needs to be satisfied, therefore, we designed the minimal *η* to be of 0.5 J/mm, in which the *P*, *v* and *Q* ~*v*~ are 200 W, 400 mm/s and 10.287 J/mm^3^, respectively. A plenty of laser parameters were orthogonally designed with *P*, *v* and *η* setting in the range of 200--370 W, 100--400 mm/s, and 0.5--3.7, respectively.
3.2.. Parameters optimization {#S0009}
-----------------------------
Figure [3](#F0003){ref-type="fig"} shows the optical images of SLM-produced pure tungsten parts. Figure [3](#F0003){ref-type="fig"}(a) reveals the relationships between the sintering formability and the laser parameters, where the specimens produced with *η* ~1~ = 0.500, *η* ~2~ = 0.625, *η* ~3~ = 0.667, *η* ~4~ = 0.750, *η* ~5~ = 0.833 and *η* ~6~ = 1.000 J/mm (marked in yellow background color) present better sintering formability. Thus, the parameter window to obtain a good, structurally sound component ranges between *η* values of 0.5--1.0 J/mm, with the corresponding *P* and *v* covering the range of 200--300 W and 200--400 mm/s, respectively. Further increasing the linear energy leads to burning loss and surface corrugation, which destroyed the forming quality and hindered the powder recoating. Besides, even the same linear energy, the different combination between *P* and *v* presented distinct forming qualities, for example, when the linear energy was in the same value of *η* = 1.0 J/mm, the specimens prepared with *p* = 200 W and *v* = 200 mm/s show better sintering formability than these with *p* = 300 W and *v* = 300 mm/s. This is because the lower speed allowed more time for pools wetting and spreading, which compensated the intrinsic low flowability of tungsten. Figure [3](#F0003){ref-type="fig"}(b) shows the optical images of an SLM-produced thin-wall (0.4 mm in thickness) tungsten part and some specimens with the *η* ~3~ linear energy. The shining and smooth surface without any macrocracks and balling certifies reasonable laser parameters and high sintering quality.
######
Optical images of SLM fabricated pure tungsten parts: (a) blocks fabricated with different linear energies; (b) 0.40 mm thin-wall tungsten part and specimens produced with *η* ~3~ = 0.667 J/mm.
3.3.. Surface morphology characterization {#S0010}
-----------------------------------------
Figure [4](#F0004){ref-type="fig"} shows the untreated fresh surface morphology and roughness of SLM fabricated pure tungsten taken from horizontal cross-sections. A relatively smooth and dense surface with regular liquid fronts is obtained and exhibited in Figure [4](#F0004){ref-type="fig"}(a). No balling or individual unmelted particles can be observed, showing that all the laser tracks have good metallurgical bonding with each other excepting some scattered black slags. Microcracks can also be observed through the inset high-magnification SEM image in Figure [4](#F0004){ref-type="fig"}(a). Normally, cracks in SLM processed parts are caused by thermal residual stresses, which arise from two mechanisms, i.e. thermal gradient mechanism (TGM) and the cool-down phase of molten top layers \[[@CIT0029]\]. Additionally, high brittleness and insufficient plasticity of pure tungsten also contribute to the formation of cracks. High-magnification SEM observation on the liquid fronts is provided in Figure [4](#F0004){ref-type="fig"}(b), massive nanosized columnar crystals are perpendicular to the fronts moving directions, suggesting an extremely high cooling rate of molten pools. In fact, the ultra-high cooling rate of laser processing could reach the order of 10^10^ K/s \[[@CIT0030]\], and the relative high thermal conductivity (173 W·m^−1^ K^−1^) also contributes to the high cooling rate and grain refinement.
######
Surface morphology and roughness taken from horizontal surfaces of SLM fabricated pure tungsten: (a) SEM image showing regular laser tracks (*η* ~3~ = 0.667 J/mm) and microcracks (inset image); (b) corresponding high-magnification SEM image showing massive nanocrystals in the liquid fronts; (c) the corresponding 3D topography image of the untreated fresh surface and (d) relationships between surface roughness and linear energy summarized from the 3D topography images.
![](T
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] |
's meaning, it retained something of the opprobrium with which Grandpa had infused it—so much so that, when Josh, aged twelve, answered the old man's use of it by declaring that he didn't get what the big deal about hippies was, Rachel flinched, as if her brother had shouted "Motherfucker!" at him.
Given Grandpa's reaction, he might as well have. Already sour, his voice chilled. "Oh you don't, do you?" he said.
Josh maintained his position. "No," he said. "I mean, they were kind of weird looking, I guess, but the hippies were into peace and love. Isn't that what everyone's always telling us is important, peace and love? So," he concluded, a lawyer finishing his closing argument, "hippies don't sound all that bad, to me."
"I see," Grandpa said, his phrasing given a slight slur as he bit down on the stem of his pipe. "I take it you are an expert on the Hippie Wars."
The name was so ridiculous she almost burst out laughing. Josh managed to channel his amusement into a question. "The Hippie Wars?"
"Didn't think so," Grandpa said. "Happened back in 1968. Damned country was tearing itself apart. Group of hippies decided to leave civilization behind and live off the land, return to the nation's agrarian roots. Bunch of college drop-outs, from New Jersey, New York City. Place they selected for this enterprise was a stretch of back woods belonged to a man named Josiah Sparks. He and his family had shared a fence with our people for nigh on fifty years. Good man, who didn't mind these strangers had settled themselves on his land without so much as a by-your-leave. 'Soil's poor,' he said. 'Snakes in the leaves, bear in the caves. If they can make a go of it, might be they can teach me something.' All through the spring and summer after they arrived, he left them to their own devices. But once fall started to pave the way for winter, Josiah began to speak about his guests. 'Kids'll never make a winter out there,' he said. Good, folks said, it'll send them back where they came from. Josiah, though—it was as if he wanted them to succeed. Not what you would've expected from a marine who'd survived the Chosin Reservoir. One especially cold day, Josiah decided it was past time he went up and introduced himself to his tenants, found out what assistance he could offer them.
"Turned out, they didn't need his help. Could be, they had in the weeks right after they'd arrived. In the time since, they'd figured out a crop they could tend that would keep them in money: marijuana. When Josiah went walking into their camp, that was what he found, row upon row of the plants, set amongst the trees to conceal them. He hadn't spoken two words to them before one fellow ran up from behind and brought a shovel down on Josiah's head. Killed him straight away. Hippies panicked, decided they had to get rid of his body. They had a couple of axes to hand, so they set to chopping Josiah to pieces. Once their butchery was finished, they dumped his remains into a metal barrel along with some kindling, doused the lot with gasoline, and dropped a match on it. Their plan was to mix the ashes in with their fertilizer and spread them over their plants. Anything the fire didn't take, they'd bury.
"Could be their scheme would've worked, but a couple of Josiah's nephews decided their uncle had been gone long enough and went searching for him. They arrived to what smelled like a pork roast. Hippies ambushed them, too, but one of the brothers saw the fellow coming and laid him out. After that, the rest of the camp went for them. They fought their way clear, but it cost an ear and a few fingers between them.
"By the time Josiah's nephews returned with the rest of their menfolk and what friends they could muster, the camp had improved its armament to firearms, mostly pistols, a few shotguns. I figure they were supplied by whoever had partnered in their little enterprise. For the next week, your peace and love crew proved they could put a bullet in a man with the best of them. They favored sneak attacks—sent a handful of men to the hospital.
"So you'll appreciate why I do not share your view of the hippie, and you'll understand my views, unlike yours, are based in fact."
Neither Rachel nor Josh questioned that their visit was over. She picked up her cane. As they stood to leave, however, Josh said, "Grandpa?"
"Hmm?"
"Weren't you already living up here with Grandma in 1968?"
"I was."
"Then how did you know about the Hippie Wars?"
Grandpa's chair creaked as he leaned forward. "You think I'm telling stories?"
"No sir," Josh said. "I was just wondering who told you."
"My cousin, Samuel, called me."
"Oh, okay, thank you," Josh said. "Did you go to Kentucky to help them?"
Grandpa paused. "I did," he said. His voice almost light, he added, "Brought those hippies a surprise."
"What?" Josh said. "What was it?"
But their grandfather would say no more.
4. The Tape (2): Down the Well
"—the shore of a dried-up lake," Grandpa was saying. "Looked like an old well, but if you'd dropped a bucket into it, you'd have come up empty. Ventilation shaft, though Jerry thought it might've helped light the place, too. He lowered me down, on account of he was a foot taller and a hundred pounds heavier than I was. Played football at Harvard, was strong as any of the roughnecks. The shaft sunk about fifty feet, then opened out. I switched on my light, and found myself dangling near the roof of a huge cavern. It was another seventy-five feet to the floor, and I couldn't tell how far away the walls were. The rock looked volcanic, which set me to wondering if this wasn't an old volcano, or at least, a series of lava tubes."
"Was it?" Uncle Jim asked.
"Don't know," Grandpa said. "I was so concerned with what we found in that place, I never managed a proper geological survey of it. I'd stake money, though, that it was the remains of a small volcano."
"Okay," Jim said. "Can you talk about what you found there?"
"It was a city," Grandpa said, "or a sizable settlement, anyway. Maybe two-thirds of the cavern had collapsed, but you could see from what was left how the ceiling swept up to openings like the one I'd been lowered through, which gave the impression of enormous tents, rising to their tent poles. Huge pillars that joined ceiling to floor added to the sensation of being under a great, black tent. Iram had also been called the city of the tent poles, and standing there shining my light around it, I could see why."
"But how did you know it was a city, and not just a cave?"
"For one thing, the entrance I'd used. We took that as a pretty clear indication that someone had known about the place and used it for something. Could've been a garbage dump, though—right? We found proof. Around the perimeter of the cavern, smaller caves had been turned into dwelling-places. There were clay jars, metal pots, folded pieces of cloth that fell apart when we touched them. A few of the caves led to even smaller caves, like bedrooms. There was evidence of fires having been kept in all of them. Plus, most of the walls had been written on. I didn't know enough about such things to identify it, but Jerry said it resembled some of what he'd seen on digs down in Dhofar."
"You must have been pretty excited," Jim said. "I mean, this was a historic find."
"It was," Grandpa said, "but we weren't thinking about that. Well, maybe a little bit. May have been some talk about an endowed chair at Columbia for Jerry, a big promotion for me. Mostly, we were interested in the tunnels we saw leading out of the cavern."
5. Family History
Officially, Grandpa had been retired from the oil company since shortly before Rachel's birth, when a series of shrewd investments had vaulted him several rungs up the economic ladder. His money had covered whatever portion of Rachel's appointments with a succession of retinal specialists her father's teacher's insurance did not, and he had paid for all of the specialized schooling and instruction she had required to navigate life with minimal vision. To Rachel's mother, in particular, her grandfather was a benefactor of whose largesse she was in constant need of reminding. To Rachel, he was a sharp voice which had retained most of the accent it had acquired growing up among the eastern Kentucky knobs, when a talent for math and science had allowed him to escape first to the university, then to the world beyond, working as a geologist for the American oil companies opening the oil fields of Saudi Arabia. The edge with which he spoke matched what
|
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] |
says it's not just robots taking over, but automation in general."You drive to a McDonald's and instead of seeing five cashiers, you just see one cashier and you see 20 tablet inputs," he said. recent study by the Century Foundation listed the cities most affected by robots.The top five markets when it comes to robot workers are Detroit, Phoenix, Houston, Chicago and No.1 is the Los Angeles area consisting of L.A. Long Beach and Santa Ana, where there are 145 human workers for every robot."Right now, we have a lot of mass produced manufacturing being done in places like China, Vietnam and so on," Moenius said. "So, fast forward 10, 15, 20 years, thanks to automation, we can do the mass production here in the United States cheaper because we save on all the transportation and coordination costs.""It means a lot of the importance we now place in the ports of L.A. and Long Beach may no longer be justified," Moenius added.That means the very jobs that have flourished in the Inland Empire over the past 20 years could soon be gone."Exactly the slice of the job market that was so rich in the last 20 or 30 years, that's going to be under attack, and that's what keeps me up at night," Moenius said.Not that the news is all bad. Moenius said the technology could lead to more free time for other activities.Q:
cannot activate journey builder interactions
I am trying to activate a interaction in journey builder but it gives me a general error message. This is a custom trigger that is built using the hubexchange app. Is there a way to view what the specific error is?
I have tried trying multiple things in from the legacy to the new platform api. I have read through the trouble shooting section as well.
https://code.exacttarget.com/app-development/journey-builder-development/platform/creating-platform-triggers.html
I can activate a event that is not my custom trigger event. Trigger and activity seem to load find in the journey builder. I my example activity I don't have a custom activity, just trying to publish my custom trigger. I am using example code https://github.com/ExactTarget/journey-builder-custom-hello-world
I don't see any errors in the browser inspection related to trigger. I am currently using chrome 39.0.2171.71 (64-bit).
A:
Sorry to hear you're experiencing a problem activiating your Interaction.
You can in fact find more detail. Open Developer Tools in Chrome, Click Activate on your Interaction, and under the Network Tab search for publishStatus. Check the response for this request and it should include an error code and a more specific message.
Typically we see this error when there is an issue with activating an interaction which contains an email activity which has an incorrect personalization string stored but there could be a different less frequest issue.
We also will correct the generic message so that more detail will be available on the canvas in the future.
Please let me know if you require any further assistance.
Sigfús Eymundsson
Sigfús Eymundsson (1837–1911) was an Icelandic photographer and bookseller.
He practiced bookbinding from a young age and in 1857 he went to Copenhagen to study the profession. In 1861 he went to Norway where he studied photography. He then operated a studio in Copenhagen for a year and a half before moving back to Iceland in 1866. In 1867 he opened the first commercial studio in Reykjavík. He also founded the Eymundsson bookstore and published a number
of books.
References
Inga Lára Baldvinsdóttir. "Iceland", Photography Encyclopedia. http://www.answers.com/topic/iceland?cat=travel
"Sigfús Eymundsson bóksali", Óðinn, March 1907. http://www.timarit.is/?issueID=302351&pageSelected=0&lang=0
Category:1837 births
Category:1911 deaths
Sigfus EymundssonThe artist known as "Fernando" once washed up on the shores of Uruguay after a freak boating accident off the coast of Carilo, Buenos Aires in 2008. Presumed dead, what in fact happened was a serendipitous encounter between the lucky survivor and a roaming associate of International Feel, who, during a walk along the sands of Punta Del Diablo, found an airtight USB stick clutched inside the hand of a partial amnesiac, dazed and shivering, but with a sly smile stretched across his sun- and sea-worn face. It seems that whatever Fernando was looking for, he had found, and now this EP sees the light of day.È morto a Roma, a 82 anni, Stefano Delle Chiaie, politico di estrema destra e fondatore dell’organizzazione neofascista Avanguardia Nazionale. Delle Chiaie era nato a Caserta il 13 settembre del 1936 e fra tre giorni avrebbe compiuto 83 anni.
Aderì al MSI (Movimento Sociale Italiano) a 14 anni; a 20 anni ne uscì per seguire Pino Rauti in Centro Studi Ordine Nuovo e nel 1960 fondò Avanguardia Nazionale, poi sciolta nel 1976 per effetto della legge Scelba, che nel 1952 aveva introdotto il reato di apologia del fascismo. Nel 1982 venne accusato di aver preso parte alla strage di piazza Fontana e nel 1989 fu assolto «per non aver commesso il fatto»; la sentenza fu confermata in appello nel 1991, quando fu prosciolto anche dall’accusa di associazione eversiva. Venne indagato anche per aver partecipato alla strage alla stazione ferroviaria di Bologna nel 1980, e venne assolto per «insufficienza di prove». Delle Chiaie fu a lungo latitante: lasciò l’Italia nel 1970 dopo essere stato chiamato a testimoniare nel processo per la strage di piazza Fontana e visse in vari paesi del Sudamerica fino al 1976, quando fu arrestato a Caracas, in Venezuela.Pages
Tuesday, February 16, 2010
Mojo Monday Time
The layout of this card is the Mojo Monday sketch by Julee Tilman. The colors (Perfect Plum, Pale Plum & Soft Suede) with a touch of dessert (to use any critter - butterfly, bird, animal, etc.) were from Betty's color challenge on SCS. I was tempted to add some green, but decided I'd play 'by the book'. :-) I'm not really happy with it, but decided it was too late to make something else. No time for stamping in the morning thanks to a hair appointment. This card is pretty straight forward with a lot of punching and only the sentiment is stamped. Thanks for stopping by...it's a bone-chilling 20 degrees right now!
5 comments:
You are braver than I am, Wanda! I have passed on this sketch for now as those off angle panel mess with my anal side big time LOL!
Sorry to hear it is so cold out your way! We could use some lower temps out our way or we will be admitting a few of the outdoor event organizers to the loony bin. Waaaay too warm and lots of rain forecast for today but thankfully some clear skies and sunshine coming for the next week so the temps should drop a bit and stabilize things a bit.
Welcome to my blog...an online journal of my paper crafting hobby. When I'm not in my stamp room, I'm probably working at my full-time job as a rehabilitation RN. I'm so happy to have you visit my blog and I appreciate when you take time to comment!
.
'
Color Throwdown Design Team
.
.
MY SPLITCOASTSTAMPERS GALLERY
OCC: Watercolor for Card Makers
On an oily side note...
.
In 2015 I began using Young Living Essential Oils and have been enjoying their benefits ever since! I love how they support so many body systems and are free of any chemicals that are so prevalent in everyday products we use! I'd love to answer any questions you may have or help you with a purchase if you're interested.
You can view the catalog by clicking on the logo above.
If you decide to order a kit to get the 24% wholesale discount on your own, or you order through the website, please mention my ID #2936458 as a referral. I’d be so grateful. You can go HEREto go to the sign-up page. Feel free to email me at cullenwr@yahoo.com if you have any questions!
Happy to be published! Pg. 66
Check out page 76 - I have another card published! Great issue for so many masculine card ideas!Auditory cortex tracks the temporal regularity of sustained noisy sounds.
Neuroimaging studies have revealed dramatic asymmetries between the responses to temporally regular and irregular sounds in the antero-lateral part of Heschl's gyrus
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] |
everything,' Slattery said, brushing the flies from his face. 'Jeez, if the world needed an enema this is where they'd stick the fucking tube.'
Elliot glanced at McCue, who had remained silent throughout their journey. He was impassive, his face betraying no trace of emotion. But his eyes missed nothing, and Elliot sensed a tension in him. He was beginning to regret having come here at all.
They climbed the steps and entered the empty hut. It was a shambles: two-tier bunk beds down one wall, crates of beer stacked against another and under the beds, empties strewn everywhere. Slattery kicked one across the floor and it rolled into a corner. There was a large desk and a swivel chair by the window. An electric fan whirred and clattered on the desk making erratic sweeps and stirring the papers strewn across the desktop. Several sheets had fallen to the floor. Crumpled cigarette packs lay on the desk, ashtrays brimming with half-smoked cigarettes. A window blind had slipped down to hang at an angle. The floorboards were crusted with dried spittle and the room stank of human sweat and stale cigarette smoke.
'Cosy little place,' Slattery said, and spat out a fly that had crept in at the corner of his mouth.
Tuk turned in the doorway. 'Ah, here comes the Marshal now.'
Van Saren strode across the compound towards the hut, a small figure, ridiculous in US army trousers tied above the ankles, open sandals, a khaki shirt open to the waist and a pork pie hat set squarely on his head. A large crucifix hung round his neck, glinting in the sunlight. He had a cocky swagger emulated by the three thugs who accompanied him, all in khaki, bandoliers slung across shoulders, AK-47s tucked under arms. Each had a dirty scarf tied around his head.
Van grinned as he saw Tuk, revealing several gaps in a mouthful of yellowed teeth. He greeted him in Thai. The thugs ignored the newcomers, pushing past and propping their automatic rifles against the far wall. One climbed on to one of the top bunks and flopped across the sweat-stained sheet. Another dropped into the swivel chair and cast an indifferent glance over the strangers. The third sat on the edge of the desk and lit a cigarette.
Tuk made the introductions. He seemed out of place and ill-at-ease in these surroundings, dabbing again at his forehead with a now grubby handkerchief. 'Saren, this is Mr Elliot and his colleagues.'
Elliot nodded and Van looked at them appraisingly before smiling broadly, as though proud of his bad teeth. 'Welcome to Mak Moun,' he said. 'Here you under my protection. Protection of Khmer Serei.' He paused. 'You want go Cambodia, Than tell me. No problem. You enjoy stay my country.' And he laughed uproariously, pleased with his joke. 'I take you. No problem. When you want go?'
'A week or so,' Elliot said. 'But I want to talk to some of your refugees first.'
Van waved a hand dismissively. 'They talk you. No problem. I tell them. You want drink?'
'Sure.'
Van giggled. 'Hah! "Sure." I like "Sure."' And he snapped an instruction at the thug sitting on the desk. Wordlessly the man rose and opened half a dozen bottles of beer to hand them round.
'Not for me, Saren,' Tuk said.
Van chuckled. 'Sure you drink with us, Than. No problem.' He turned to Elliot. 'Than like glass with beer from refrigerator. He think we very uncivilized here.'
Tuk took a bottle reluctantly from the thug, who showed his first emotion in an evil grin. Van said something in Cambodian and all the thugs laughed. Then he raised his bottle. 'Death Khmer Rouge bastard!' he shouted.
Elliot took a swig from his bottle. The beer was hot.
The sound of raised voices made them turn. Through the open door, across the compound, outside the administration hut, they saw two white men engaged in an argument. One was big, unshaven, wearing jeans and a T-shirt, a Colt.45 stuck in his paunch. The other man was smaller, fair-haired, in pressed trousers and white shirt. The argument was heated and in English, although from the hut there was no telling what they were saying.
Suddenly the big man stepped forward and pushed the other back, his voice rising to a pitch of fury. The smaller man stood his ground, trying to calm aggression with reason. Then the big man swung a fist like a football and hit him full in the face, so that he staggered back and fell in the dust, blood pouring from his nose. As the big man advanced he scrambled backwards, getting hurriedly to his feet. He stood off, holding a handkerchief to his face, shouting angry words before turning and striding quickly to a jeep parked at the edge of the compound. He got in and drove off fast, tyres spinning in the dirt.
As the big man started towards their hut, Van turned grinning to the others. 'That Garee,' he said. 'He clearing today food distribution with Red Cross. No problem.'
Tuk moved next to Elliot and said quietly, 'I would advise caution with this man. He can be – unpredictable.' He turned to McCue. 'A fellow countryman of yours, Mr McCue.' And Elliot saw McCue's jaw set.
'Cool it, Billy boy,' Slattery said softly. McCue said nothing.
The big American climbed the steps and stopped in the doorway, taking in the new faces. 'Who the hell are these guys!' He didn't look happy to see them.
'Friends of Mr Tuk, Garee,' Van said. 'They want we take them cross border.'
The American grunted.
Tuk said, 'Mr Ferguson is Saren's Minister of Defence for the National Liberation Movement of Cambodia.' Elliot picked up the irony, but it seemed to elude Van and Ferguson.
'Marshal Van is the father and saviour of all Cambodia,' Ferguson said, in a way that defied anyone to contradict him. He pushed his way past McCue and Slattery and flicked his head at the thug in the swivel chair. It was vacated at once. Ferguson slumped into the chair. 'Fucking Red Cross think they own the place!' His feet thudded on to the desk.
'You tell them different, Garee,' Van said.
'Fucking right I do.' He looked at Elliot. 'And I'm not taking any shit off you guys either. Got that?'
'Sure,' Elliot said evenly.
'Hah,' giggled Van. '"Sure." I like "Sure."'
But Ferguson was glaring with ugly hostility at Elliot. 'I don't like your tone, pal. You show some respect for my father.'
Elliot looked at him steadily. 'I'm surprised you have one.'
Ferguson frowned. He simmered for a moment, then seemed to explode from the inside out. 'Marshal Van is my father! You trying to say something different?' He was on his feet, hands on his hips, swivel chair clattering backwards.
Elliot said, 'I said I didn't think bastards had fathers.'
Slattery wondered at Elliot's coolness and he began to feel good, adrenalin pumping. He glanced quickly round the room. The three thugs were taut and alert. Tuk was pale with fear and had stepped back towards the door. Van just watched, apparently quite relaxed. Outside somewhere a baby was crying. Ferguson was puce with rage. He drew his pistol from his belt and levelled it at Elliot's head.
'You apologize to my father!' he shouted. 'Or you're a dead man!'
Slattery caught the slightest movement out of the corner of his eye, and a long blade glinted at Ferguson's throat, the point drawing blood. McCue. He'd forgotten about McCue. Slattery swivelled round, snatched an AK-47 from the wall and turned it on the three thugs, almost before they could move. 'Don't even think about it, boys.'
Ferguson had gone rigid and he glanced quickly sideways to see McCue's face very close to his own. He felt the heat of his breath, smelled the beer on it. McCue's eyes chilled him. 'Move that trigger a hair's breadth and I'll cut your fucking head off – pal.' McCue's voice was barely a whisper.
Elliot reached out and took the Colt from Ferguson's hand and tucked it back in the belt below his paunch. 'Didn't anyone ever tell you it's dangerous to point guns at people?' he said.
The tension was broken by Van's laugh, high-pitched, almost a giggle. 'Good. Very, very good. Nice thing they on our side, huh Garee?'
Elliot nodded to McCue and Slattery. Slattery lowered the automatic and McCue slowly withdrew the knife, his eyes never leaving Ferguson for a moment. Ferguson slapped at his neck and looked at the blood smeared on his fingers. 'Hey, you guys,' he said. 'Just
|
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for the senses, indeed.
A soft, light, monochrome palette runs through the interior. A calming decorative approach is key in the living room with its balanced lines, natural textures - and no clutter at all. Hoppen is a keen advocate of the Chinese art of feng shui and believes that such spatial discipline allows for positive living vibes. In the foreground, a huge low-level wenge wood coffee table holds three shallow Perspex trays. A white rose floats in each. On the wall and propped against the wall are black and white photographs collected by the designer.
"It's all a bout balance and harmony," says Hoppen concerning her subtle Eastern aesthetic. " I make spaces that work for people." Her functional dining room includes nature as much as possible in the decorative scheme. Narrow, rectangular display niches provide the perfect location for single stemmed lilies in slim, clear glass vases.
Preferring texture to colour, Hoppen likes to create a sense of informal luxury by using contrasting materials: dark wood, suede, velvet, silk and chenille. In the bedroom (above), the bed is dressed with piles of cushions and sumptuous bed linens in neutral tones; by the window is an Oriental version of a traditional dressing table made of wenge wood.
Ordered interiors promote relaxation and a sense of well-being. And nowhere is this more so than in the bathroom which plays on the Eastern love of bathing. In front of the grid windows are a set of five wood plant holders-three of which are topped with leafy fronds. A traditional bathtub, ideal for soaking in, has been balanced on two blocks of wenge wood and lit from beneath to give it the impression of floating in space.
##
Contemporary Flair
Contemporary with a Chinese twist, this clean-lined apartment in the heart of Hong Kong's busy Mid-Levels residential district is a superb example of traditional motifs used in a totally modern manner. When designing this compact 74 sq m (800 sq ft) space, architect Johnny Li of Nail Assemblage went back to his cultural roots to formulate a new language of design. Instead of opting for the traditional rosewood furniture look, or placing clean-lined antiques in a contemporary interior, Li chose to focus on the elements that define Chinese style and apply them to a modern design.
Li took inspiration from the layout of historical Chinese buildings. "Traditionally, Chinese architecture used a frame system of openings to suggest more space beyond," he explains. He interpreted this by fitting dining room windows with latticed walnut screens (backed by bamboo blinds and a row of plants) to evoke the impression of an Imperial garden outside. In the wood-clad entranceway he hung a huge, door-sized photograph of traditional Chinese moongates and down the corridor, used a rich purple curtain to disguise a door at the end. This device adds depth to the hallway and hints at a private zone beyond.
By custom-making all the furniture, Li was able to reinterpret Chinese ideas in a contemporary fashion and ensure that every piece fitted the compact space perfectly. He took the decorative Chinese symbol meaning 'cloud' and integrated its spiralling shape into a coffee table-cum-stool, bedside tables and bed legs. His cherrywood and velvet dining table and six-sided stools were inspired by traditional hexagonal Chinese garden furniture, and the decadent red acetate-fringed lampshades hanging in the bedroom are reminiscent of an opium den. On the same theme, an impressive modern adaptation of a Chinese opium bed with footstool appears to 'float' in the study
Offsetting the pared-down design and neutral colour scheme are modern materials and bright accents. Instead of traditional Chinese blackwood, gilt, lacquer and silk, Li opted for cherrywood, stained maple, stainless steel and Perspex. Colours are those normally associated with Oriental style, such as turquoise, purple and red. "I designed simplified traditional shapes using new materials. It was a creative experience as well as an educational one. It was also an exercise in learning about my roots."
At the end of the corridor, Li hung a rich, shimmering purple curtain to disguise the door leading to the spare room beyond. This helps suggest there is more space than meets the eye, a valuable design tool for Hong Kong living. A slatted dual tone wood box is an interesting way to disguise an ugly air conditioner. The painting is by Lee Chi Cheung, a well-known Chinese watercolourist from Hong Kong.
The fact that traditional Chinese courtyard dwellings used a system of openings to suggest more space beyond proved inspirational for this hallway which leads into the living and dining areas. In a nod to Chinese gardens, architect Johnny Li enlarged a photograph of the old moongates in the grounds of Hong Kong's Repulse Bay hotel to poster size and positioned it over a door leading to a storeroom. The dining room windows have been fitted with latticed walnut screens with plants behind. The hexagonal cherrywood dining table and velvet-topped stools are based on traditional garden furniture designs; above hangs a pink Perspex lantern.
In the bedroom, the red-fringed acetate lampshades are more decadent opium den than 21st-century style. Roller blinds fit flush to the window to provide privacy without sacrificing space. The bedside tables and the bedlegs (not pictured) incorporate the spiralling cloud motif.
Reflecting on his cultural roots, Li came up with a new take on traditional Chinese style by focusing on its inherent decorative elements and adding a 1950s retro twist. In the living room (opposite, top), a modern cream sofa was custom-made to fit. Lining the wide windowsill with futon-base material and adding some cushions provided additional seating. Li also designed a stained maplewood coffee table-cum-stool based on the Chinese symbol for 'cloud'. The walls in the entrance hall have been clad with wood to provide shelving for the owner's collection of books.
In the study, a modern adaptation of a Chinese opium bed is fastened to the walls at either end of the small room. Lit from beneath, it seems to float in space. In this room, contrasting textures are key: the wood veneer bed, the stainless steel and maplewood side table (again a modern interpretation of a traditional design) and an antique dark wood cabinet. Overhead is a modern anglepoise lamp, ideal when extra light is needed for reading or for working on a laptop computer. To make such activities easier, a clear Perspex bed tray has been placed on top of the bright turquoise futon cover (a colour often associated with Chinese style).
##
Space and Light
On Dean Street, in the centre of London's bustling Soho district, stands a l1960s-built former synagogue. Today, worshipping takes a different form here as the concrete-framed building has recently been converted into an innovative new complex to house the Soho Theatre Company. In a new take on urban recycling, the architects behind the project-husband and wife team Paxton Locher-have turned the seven-storey structure into. a multifunctional building with residential apartments on top, hospitality outlets below and a theatre sandwiched in the middle.
The project was completed in alliance with the Arts Council and a Lottery Grant that paid for the theatre, restaurant and bar on the first four floors The top three floors were developed by Vinestone Limited and comprise four duplexes of 163 sq m (1,750 sq ft) and one single floor penthouse of 232 sq m (2,500 sq ft) "All the apartments feature large outdoor spaces and patios," explains Gee Thomson of Vinestone. Two have double-height terraces carved into the facade overlooking the street; another two face away from the street with sloping retractable glass roofs.
In one such duplex, what is essentially an ultra-modern interior has been filled with a collection of classic Chinese furniture from London's Beagle Gallery With its huge glass windows and open-plan layout, the cool, almost-clinical space is tempered by the warm wood antiques. Contrast is the secret to decorative success here. Fresh and modern, the architecturally minimal interior has been furnished with both natural and quasi-industrial elements-including crisp white linens, warm wooden floors and an open metal stairway joining the two levels. The open plan space is large and free-flowing, with walls kept to a minimum to allow light to flood in.
Urban recycling in action: In this duplex an open staircase leads to a mezzanine level study above; a kitchen and terrace are positioned to the left. Four Qing dynasty chairs-two 18th-century elmwood chairs with stone insets and two 19th-century elmwood chairs, all from northern China-are arranged around a 19th-century day bed with a cane top.
The open-plan living room has been furnished with a mix of Chinese antiques and modern pieces and features huge sloping windows which let in lots of light. Two large, comfortable white sofas flank a modern metal and glass coffee table. On top is a 19th-century leather and black lacquer hatbox. Against the wall is an elmwood altar table from northern China, also from the 19th century. All the antiques are from Beagle Gallery.
Looking from the office into the dining area beyond: The open plan proportions of the space enable clear views from one room into another. Concrete columns add visual interest without creating a closed-in feel. An 18th-century southern
|
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and the following disclaimer.
</li>
<li>
<var class="replacable-license-text">2.</var>
Redistributions in binary form must reproduce the above copyright notice, this list of conditions
and the following disclaimer in the documentation and/or other materials provided with the
distribution, and in the same place and form as other copyright, license and disclaimer
information.
</li>
<li>
<var class="replacable-license-text">3.</var>
The end-user documentation included with the redistribution, if any, must include the following
acknowledgment: "This product includes software developed by The XFree86 Project, Inc
(http://www.xfree86.org/) and its contributors", in the same place and form as other
third-party acknowledgments. Alternately, this acknowledgment may appear in the software
itself, in the same form and location as other such third-party acknowledgments.
</li>
<li>
<var class="replacable-license-text">4.</var>
Except as contained in this notice, the name of The XFree86 Project, Inc shall not be used in
advertising or otherwise to promote the sale, use or other dealings in this Software without
prior written authorization from The XFree86 Project, Inc.
</li>
</ul>
<p>THIS SOFTWARE IS PROVIDED ``AS IS'' AND ANY EXPRESSED OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED
TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN
NO EVENT SHALL THE XFREE86 PROJECT, INC OR ITS CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT,
INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT
OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER
CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING
NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
POSSIBILITY OF SUCH DAMAGE.</p>
</div>
<h2 id="licenseHeader">Standard License Header</h2>
<div property="spdx:standardLicenseHeader" class="license-text">
<p style="font-style: italic">There is no standard license header for the license</p>
</div>
<div property="spdx:standardLicenseTemplate" style="display: none;">
<<beginOptional>> XFree86 License (version 1.1)<<endOptional>> <<var;name="copyright";original="Copyright (C) 1994-2006 The XFree86 Project, Inc. All rights reserved.";match=".{0,1000}">> Permission is hereby granted, free of charge, to any person obtaining a copy of this software and associated documentation files (the "Software"), to deal in the Software without restriction, including without limitation the rights to use, copy, modify, merge, publish, distribute, sublicense, and/or sell copies of the Software, and to permit persons to whom the Software is furnished to do so, subject to the following conditions: <<var;name="bullet";original="1.";match=".{0,20}">> Redistributions of source code must retain the above copyright notice, this list of conditions, and the following disclaimer. <<var;name="bullet";original="2.";match=".{0,20}">> Redistributions in binary form must reproduce the above copyright notice, this list of conditions and the following disclaimer in the documentation and/or other materials provided with the distribution, and in the same place and form as other copyright, license and disclaimer information. <<var;name="bullet";original="3.";match=".{0,20}">> The end-user documentation included with the redistribution, if any, must include the following acknowledgment: "This product includes software developed by The XFree86 Project, Inc (http://www.xfree86.org/) and its contributors", in the same place and form as other third-party acknowledgments. Alternately, this acknowledgment may appear in the software itself, in the same form and location as other such third-party acknowledgments. <<var;name="bullet";original="4.";match=".{0,20}">> Except as contained in this notice, the name of The XFree86 Project, Inc shall not be used in advertising or otherwise to promote the sale, use or other dealings in this Software without prior written authorization from The XFree86 Project, Inc. THIS SOFTWARE IS PROVIDED ``AS IS'' AND ANY EXPRESSED OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE ARE DISCLAIMED. IN NO EVENT SHALL THE XFREE86 PROJECT, INC OR ITS CONTRIBUTORS BE LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE) ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE POSSIBILITY OF SUCH DAMAGE.
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</html>
Q:
Div and table width won't stick to it's original form and will grow out of line
I have created a html using XSLT and XML, and transformed it with java and my problem is:
I've created some fields to be populated but if i insert more text than the box size it will grow in lenght instead of height and i don't want it to grow in width, i want it to be exactly what i set.
Here is the code :
......
<xsl:template name="bodyGEO">
<table width="770" cellspacing="0" cellpadding="0" border="0" >
<tr height="10"><td/></tr>
<tr>
<td valign="center" width="770" colspan="2">
<table width="770" cellspacing="0" cellpadding="0" border="0">
<tr>
<td width="385">
<b>
<xsl:variable name="id" select="//Product/Content/Resource/Data/TextElement[@clientCode='cme_cmb_geo_tit_1']/@elementId "/>
<xsl:variable name="max_word_count" select="//Product/Content/Resource/Data/TextElement[@clientCode='cme_cmb_geo_tit_1']/@max_word_count"/>
<DIV id="webedit" formid="{$id}" max_word_count="{$max_word_count}" comment="Title" width="385" style="background-color:#bfbfbf; max-width:385;">
<xsl:value-of disable-output-escaping="yes" select="//Product/Content/Resource/Data/TextElement[@clientCode='cme_cmb_geo_tit_1']"/>
</DIV>
</b>
</td>
<!-- <xsl
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] |
SSL" = "SSL"; then
AC_MSG_RESULT([yes])
AC_DEFINE([HAVE_CURL_SSL], [1], [Have cURL with SSL support])
save_CFLAGS="$CFLAGS"
CFLAGS="`$CURL_CONFIG --cflags`"
AC_PROG_CPP
AC_MSG_CHECKING([for openssl support in libcurl])
AC_TRY_RUN([
#include <curl/curl.h>
int main(int argc, char *argv[])
{
curl_version_info_data *data = curl_version_info(CURLVERSION_NOW);
if (data && data->ssl_version && *data->ssl_version) {
const char *ptr = data->ssl_version;
while(*ptr =='') ++ptr;
return strncasecmp(ptr, "OpenSSL", sizeof("OpenSSL")-1);
}
return 1;
}
],[
AC_MSG_RESULT([yes])
AC_CHECK_HEADERS([openssl/crypto.h], [
AC_DEFINE([HAVE_CURL_OPENSSL], [1], [Have cURL with OpenSSL support])
])
], [
AC_MSG_RESULT([no])
], [
AC_MSG_RESULT([no])
])
AC_MSG_CHECKING([for gnutls support in libcurl])
AC_TRY_RUN([
#include <curl/curl.h>
int main(int argc, char *argv[])
{
curl_version_info_data *data = curl_version_info(CURLVERSION_NOW);
if (data && data->ssl_version && *data->ssl_version) {
const char *ptr = data->ssl_version;
while(*ptr =='') ++ptr;
return strncasecmp(ptr, "GnuTLS", sizeof("GnuTLS")-1);
}
return 1;
}
], [
AC_MSG_RESULT([yes])
AC_CHECK_HEADER([gcrypt.h], [
AC_DEFINE([HAVE_CURL_GNUTLS], [1], [Have cURL with GnuTLS support])
])
], [
AC_MSG_RESULT([no])
], [
AC_MSG_RESULT([no])
])
CFLAGS="$save_CFLAGS"
else
AC_MSG_RESULT([no])
fi
PHP_CHECK_LIBRARY(curl,curl_easy_perform,
[
AC_DEFINE(HAVE_CURL,1,[ ])
],[
AC_MSG_ERROR(There is something wrong. Please check config.log for more information.)
],[
$CURL_LIBS -L$CURL_DIR/$PHP_LIBDIR
])
PHP_CHECK_LIBRARY(curl,curl_easy_strerror,
[
AC_DEFINE(HAVE_CURL_EASY_STRERROR,1,[ ])
],[],[
$CURL_LIBS -L$CURL_DIR/$PHP_LIBDIR
])
PHP_CHECK_LIBRARY(curl,curl_multi_strerror,
[
AC_DEFINE(HAVE_CURL_MULTI_STRERROR,1,[ ])
],[],[
$CURL_LIBS -L$CURL_DIR/$PHP_LIBDIR
])
PHP_NEW_EXTENSION(curl, interface.c multi.c share.c curl_file.c, $ext_shared)
PHP_SUBST(CURL_SHARED_LIBADD)
fi
Q:
SUSY - using fractions for the gutter
When I setup my grid with a map in susy
$susy: (
columns: 12,
gutters: 1/4,
math: fluid,
output: float,
gutter-position: inside,
);
It does not like the gutter as a fraction and I have had to change this to a decimal. No big deal but why if the documentation says this is how to do it does it break?
http://susy.readthedocs.org/en/latest/settings/
I am using libsass with compass-mixins installed via bower but am pretty sure this happened when I ran with compass.
A:
This is a known bug in libsass, and has already been fixed - but that fix has not trickled down into node-sass yet.
Pakistan PM commits investment in Karachi port to boost trade
Karachi is Pakistan’s major maritime link to the outside world and handles over 60 percent of the country’s imports and almost all of its exports.Middle Tennessee Glass Company - (615) 452-3628
Contact Doc's Glass Company
Doc’s Glass Service Inc.
1340 Airport Rd
PO Box 1012
Gallatin, TN 37066
(615) 452-3628
Contact Us
Thank you for your interest in Doc’s Glass Service. We love custom glass projects and we are very excited to discuss yours. Please fill out the contact form below or call us @ (615) 452-3628 to get started today!Introduction {#s1}
============
*Wolbachia* are obligatory Gram-negative bacteria infecting a great number of species of arthropods and nematodes. It has been estimated that up to 66% of insect species are infected with *Wolbachia* [@pone.0032643-Hilgenboecker1]. The widespread success of *Wolbachia* is thought to be largely attributed to their ability to manipulate their hosts\' reproduction which may selectively favor infected females. This manipulation can be accomplished through a variety of strategies such as sperm-egg cytoplasmic incompatibility (CI), parthenogenesis, feminization of males, and male-killing [@pone.0032643-Serbus1]. Furthermore, *Wolbachia* infection may also affect the olfactory response, life span, and immunity of their hosts [@pone.0032643-Peng1]--[@pone.0032643-Kambris1]. For example, *Wolbachia* strain *w*MelPop reduces the longevity of its *Drosophila melanogaster* host [@pone.0032643-Min1] and also has been shown to halve life span when artificially transferred to mosquito *Aedes aegypti* [@pone.0032643-McMeniman1]. Recent studies revealed that *Wolbachia* may function in protection against pathogenic viruses, filarial nematodes and *Plasmodium* in fruit fly and mosquito hosts [@pone.0032643-Kambris1], [@pone.0032643-Hedges1]--[@pone.0032643-Hughes1]. Infection of adult *Drosophila* with *Drosophila C virus* (DCV) can induce 100% mortality within 5∼6 days. In contrast, the flies infected with both *Wolbachia* and DCV died within 13∼14 days [@pone.0032643-Hedges1]. Furthermore, the presence of *Wolbachia* in *Aedes aegypti* inhibits the development of filarial nematodes, resulting in significantly reduction in the numbers of third larval stage worms in the mosquito [@pone.0032643-Kambris1]. In addition, highly significant reductions in *Plasmodium* infection intensity were observed in the *w*MelPop-infected *Anopheles gambiae*, indicating that *Wolbachia* infection inhibits the development of *Plasmodium* in the mosquito [@pone.0032643-Kambris2]. However, the effect of *Wolbachia* infection on the resistance of their hosts to heavy metal is unknown.
Lead (Pb) is one of the most abundant heavy metal pollutants in the environment. It is considered to be one of the most hazardous chemicals for humans and animals, since it may induce a broad range of acute or chronic behavioral, biochemical and physiological abnormalities. Pb-induced lipid peroxidation of cellular membranes has been demonstrated to play a critical role in the oxidative damage of liver [@pone.0032643-MoniuszkoJakoniuk1]. Pb may produce serious immunotoxicity to phagocytic activity as well as cellular and humoral immunity, resulting in increased host susceptibility to infection, or tumorigenesis [@pone.0032643-FernandezCabezudo1]--[@pone.0032643-Pistl1]. One of the major mechanisms concerning the toxicity of Pb is attributed to its ability to generate reactive oxygen species (ROS), which results in oxidative stress [@pone.0032643-Pande1], [@pone.0032643-Hsu1]. Studies *in vitro* have shown that NF-κB, AP-1, MEK, and JNK may be important regulators of Pb-induced signaling in gene expression mediating inflammatory response and immunomodulation [@pone.0032643-Govindarajan1]. In addition, the treatment of macrophages with Pb results in disregulation of the production of pro-inflammatory cytokines, such as tumor necrosis factor alpha (TNF-α), interleukin 1alpha (IL-1α) and interleukin 6 (IL-6) [@pone.0032643-Krocova1]. Probably it
|
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raw.githubusercontent.com/rust-lang/rls-vscode/master/package.json";
description = [[
https://github.com/rust-lang/rls
rls, a language server for Rust
See https://github.com/rust-lang/rls#setup to setup rls itself.
See https://github.com/rust-lang/rls#configuration for rls-specific settings.
If you want to use rls for a particular build, eg nightly, set cmd as follows:
```lua
cmd = {"rustup", "run", "nightly", "rls"}
```
]];
default_config = {
root_dir = [[root_pattern("Cargo.toml")]];
};
};
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Meet Our Pastor
Reverend Donnie Carl Chambers was installed as the pastor of Red Hill in October 1992. He received his Bachelor of Divinity degree May 14, 1987 from Columbia Institution in Spartanburg, SC. Reverend Chambers was ordained in 1984 at Golden Grove Baptist Church in Traveler’s Rest, SC. He served as pastor of the Goodwill Baptist Church in Greenville, SC for four years. Rev. Chambers also served as one of the associate pastors at Zion Baptist Church, Washington Street, Columbia, SC. He is affiliated with the South Carolina Congress of Christian Education and is a member of the Columbia Chapter of the NAACP. He is serves as Moderator for the Wateree Baptist Association Upper Division.
Rev. Chambers’ vision for Red Hill is to rid itself of traditional rituals that have nothing to do with reaching souls for Christ but rather to develop and equip ourselves for witnessing and sharing the Word of God. He often reminds, “People don’t care how much you know until they know how much you care.”Abuse Of India's Information Technology Act Results In India's First Arrested Twitter User
from the #guinnessbookofhorribleworldrecords dept
On 20 October, he (Ravi Srinivasan) posted a tweet to his 16 followers saying that Karti Chidambaram, a politician belonging to India's ruling Congress party and son of Finance Minister P Chidambaram, had "amassed more wealth than Vadra".
He was alluding to Robert Vadra, son-in-law of Congress party chief Sonia Gandhi, who was at the centre of a political row after allegations over his links with a top Indian property firm.
Karti Chidambaram (@KartiPC) did not take the tweet in good humour and filed a police complaint on 29 October.
They arrested Mr Srinivasan early next morning, charged him under Section 66A of India's Information Technology [IT] Act, and demanded 15 days of police custody.
[Section 66A] can send you to jail for three years for sending an email or other electronic message that "causes annoyance or inconvenience".
On the face of it, this protects citizens against online harassment.
In reality, the law is more often used by the state as a weapon against dissent. In each such case, police action has been swift and harsh.
In April, the West Bengal government led by Chief Minister Mamata Banerjee used Section 66A against a teacher who had emailed to friends a cartoon that was mildly critical of her.
And, interestingly, Section 66A has never been used against politicians.
"Free speech is subject to reasonable restrictions. I have a right to seek constitutional/legal remedies over defamatory/scurrilous tweets."
Thank you for reading this Techdirt post. With so many things competing for everyone’s attention these days, we really appreciate you giving us your time. We work hard every day to put quality content out there for our community. Techdirt is one of the few remaining truly independent media outlets. We do not have a giant corporation behind us, and we rely heavily on our community to support us, in an age when advertisers are increasingly uninterested in sponsoring small, independent sites — especially a site like ours that is unwilling to pull punches in its reporting and analysis. While other websites have resorted to paywalls, registration requirements, and increasingly annoying/intrusive advertising, we have always kept Techdirt open and available to anyone. But in order to continue doing so, we need your support. We offer a variety of ways for our readers to support us, from direct donations to special subscriptions and cool merchandise — and every little bit helps. Thank you.
–The Techdirt Team
India's somewhat schizophrenic relationship with privacy and freedom of speech has been discussed here before. The Indian government, on one hand, seems to want to do the right thing and safeguard its citizens from censorship and surveillance... but only up to a point. Once the going gets rough (i.e., outbreaks of violence, demonstrations), the government begins ramping up its surveillance and cracking down on free speakers.Given this background, it's a bit surprising to hear that India has only just recently chalked up its first Twitter-related arrest. After all, the UK and the US have been doing it for years already. The person on the receiving end of this unfortunate record-setting event made the mistake of criticizing a politician (of course).This message ("") went out to all ofand somehow found its way to Karti himself, who responded like anyone else would when mildly insulted: by contacting law enforcement...… which immediately responded with the sort of speed reserved for appeasing angry politicians.Srinivasan's single allegation could have been addressed through India's libel laws, but since that route takes time and money, the offended politician instead used the police department to take care of the "problem" by using the "sweeping power" of Section 66A of the IT Act of 2000.Loosely worded laws, ostensibly designed to "protect" citizens, usually devolve into tools of censorship. For some strange reason, those with the most power are the ones who feel the most "threatened" by open criticism and dissent. It's little wonder that legislators are more than willing to push through open-ended "cyberlaws" that can be bent to fit any situation. The end result is this fact, which is perhaps least surprising of all:To Srinivasan's credit, he refused to back down from his statement. In addition, his arrest and subsequent appearance on television led to him gaining another 2,300 followers, many of whom are wondering if his arrest was tied to his anti-corruption campaigning. Despite the public support of the arrested tweeter, the politician behind his arrest remains unrepentant, tweeting out this amazing statement in his own defense:There's nothing "reasonable" about arresting someone rather than following the "constitutional/legal remedies" set up by India's libel law. This is simple thug tactics being deployed by someone operating without fear of reprisal. Section 66A needs to be cleaned up if freedom of speech and privacy are going to be protected, rather than just paid lip service at convenient intervals.
Filed Under: arrests, india, politics, social media, speech
Companies: twitterMassachusetts Tax Collections Plummet in December
BOSTON — Reports from Beacon Hill indicate that Massachusetts is significantly behind the mark in tax collections for the month of December.
According to the State House News Service,
|
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] |
look to that new one, it's not an option used often I think and not really a security issue but it could mislead users to think their account is locked when it's not which is not nice
<seb128> let's see what robert_ancell says about the SRU
<willcooke> thanks chaps
<Laney> thx
<seb128> yw!
<willcooke> I think I worked out whats wrong with my printer
<Laney> seb128: all those code paths are a bit annoying btw
<willcooke> there is a
<Laney> lemme know if you want me to review your fix :-/
<seb128> Laney, thanks, reviews are always welcome!
<Laney> also I think upstream just removed the nopasswd stuff
* robert_ancell forgot to close XChat...
<seb128> lol
<Laney> run
<seb128> night robert_ancell
<seb128> :-)
<willcooke> *an electric motor inside which seems to drive some belt connected to the big transfer drum. It seems to be jammed and getting very hot, so I think it's just broken. A new part > cost of a new printer.
<willcooke> night robert_ancell :)
<Laney> willcooke: can you get it out?
<robert_ancell> Laney, what was my fix?
<Laney> appdata for u-c-c
<Laney> the bug got verification-failed
<willcooke> Laney, no, it's really annoying - the mounting seems to be moulded in and so getting just the motor out would break the plastic supporting the rest of the gubbins.
<robert_ancell> oh, I was looking at the nopasswd bug
<Laney> heh
<robert_ancell> night all!
<davmor2> willcooke: just buy an Air Ram mk2 if you need to vac ceilings get a multi too and be done ;)
* Sweetshark tried kvm/virt-manager and feels stupid about having VirtualBox around still.
<seb128> Sweetshark, what's wrong with virtualbox?
<seb128> Sweetshark, oh btw how did that ppa upload from yesterday go? build is done?
<Sweetshark> seb128: 5.2.6/yakkety is smoketested and moved to the libreoffice ppa, 5.3.1/zesty is uploaded and currently building in a personal ppa. 5.3.1 snap was also updated, succeeded on amd64, broke on armhf due to infra, broke on i386 in a test, but maybe a heisenbug. retried armhf, i386.
<seb128> k
<seb128> Sweetshark, let me know if/when you need sponsoring for something
<Sweetshark> seb128: willdo.
<Sweetshark> seb128: compared to vbox, kvm is just much smoother in desktop/video emulation for me for starters. installs were also really quick, so IO might be better too. but that might also just be my new hardware.
<seb128> I should give it a try again
<Sweetshark> seb128: also thorsten from #libreoffice-dev showed me he can boot into his native windows dual-boot install from the running linux, which is quite cool.
<seb128> that sounds useful
<Sweetshark> seb128: He said the only tricky thing is not to miss the grub menu, because booting into the linux install that you are currently running causes some confusion between host and guest.
<Sweetshark> "Yo dawg, We heard you like linux, so we put your linux in your linux..."
<tedg> Laney: So I have a silo building (failing on PPC) that has UAL without Upstart, but it's still blocked on s390x because of other deps.
<tedg> Laney: Do you want my to try to get those in the same silo or do you want to do "archive magic" to do rebuilds later?
<xnox> tedg, what silo? =) can i look?
<tedg> xnox: No, it's for Laney only.
<tedg> xnox: https://bileto.ubuntu.com/#/ticket/2577
<Laney> hi tedg
* xnox is *sad*
<Laney> Nice one
<Laney> tedg: It comes down to u-s-s?
<tedg> Laney: Yeah, I've pinged kenvandine about that one and he's looking into it.
<xnox> tedg, powerpc should be dropped as an architecture anyway; and s390x should not have ual as we don't support clicks/desktop there at all
<Laney> Stop it please
<Laney> tedg: Thanks, ok, sounds good
<Laney> You can upload the things into the silo to see if they work
<tedg> xnox: Well, I'm not going to argue those points. But from an academic perspective, my stuff shouldn't break there either. :-)
<kenvandine> on my todo list for this morning
<xnox> tedg, right, imho then powerpc/s390x builds should be libertine-less as we don't support graphical desktops on those arches anymore.
<tedg> xnox: Also, FWIW, this silo drops click support as well ;-)
<xnox> or at least we have for sure not ported libertine, nor tested it on powerpc & s390x
<Laney> xnox: We don't add arch-specific hacks all over the archive
<Laney> Can you please leave it?
<Laney> We're close to getting this fixed now
<tedg> For the record, if someone wanted to get me an s390x rack I could use as a desktop, I'd be happy to dogfood it :-)
<xnox> lol, ok.
<kenvandine> *happily* :-D
<xnox> Laney, ok
<Laney> thx
<Laney> tedg: kenvandine: I'll be off tomorrow and Friday, so if you could check that you can get gtk built against this then please feel free to publish
<kenvandine> sure
<Laney> after uss is fixed I would hope that libertine and then ual should get builds automatically
<Laney> assuming there's no other problem
<kenvandine> tedg, does this silo also fix the issues renatu was talking about with app starting when dbus-user-session is installed?
<tedg> kenvandine: Yes
<kenvandine> woot
<renatu> wow \o/
<tedg> kenvandine: When it's not installed though, right?
<kenvandine> application starting is sort of important :)
<kenvandine> the issue was when dbus-user-session was installed
<renatu> tedg, yes after install dbus-user-session the apps does not start from content-hub anymore.
<tedg> Okay, perhaps I'm confused then. It fixes the issue of dbus-user-session not being installed, which ual needs.
<kenvandine> yeah, that's not the issue i was talking about
<renatu> tedg, did you remember that you told me that the env vars could be wrong
<tedg> Yeah, but that's a content-hub issue.
<renatu> tedg, but only happens after install dbus-user-session
<tedg> Yes, it happens when content-hub is using systemd instead of upstart.
<tedg> Upstart has the environment of the full graphic session because it is once per session, where systemd is once per user.
<renatu> humm I tought that was transparent for content-hub
<tedg> So we have to include more environment.
<kenvandine> to be clear, content-hub is using UAL
<kenvandine> we don't use systemd directly
<tedg> That environment is getting taken from the launching process.
<kenvandine> or is it the exec-tool?
<tedg> Which *should* be the same for everyone. But somehow must be different.
<tedg> kenvandine: Wait, are we talking "applicaiton launching" or "untrusted helper launching"?
<kenvandine> i think it's both
<kenvandine> renatu, right?
<kenvandine> renatu, it's an issue with both importing and exporting?
<renatu> kenvandine, let me try. I am not sure
<kenvandine> Laney, https://code.launchpad.net/~ken-vandine/ubuntu-system-settings/no_upstart/+merge/319926
<kenvandine> Laney, perhaps you can review that
<
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1364,
50104,
907,
253,
7344,
875,
4292,
285,
29323,
422,
13001,
13,
16928,
1966,
3570,
13,
8591,
3367,
285,
5054,
17843,
13,
8338,
247,
1959,
2852,
13,
390,
29254,
253,
26183,
9099,
273,
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273,
1612,
13,
3340,
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14,
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10,
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51,
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16544,
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253,
3420,
387,
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1986,
14726,
275,
1457,
2816,
327,
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15,
2164,
13,
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15,
313,
52,
3878,
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16,
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10,
187,
187,
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27,
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45,
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281,
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187,
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15,
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335,
1574,
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281,
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13,
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273,
952,
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13,
247,
2715,
273,
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342,
253,
3918,
273,
17111,
326,
2506,
457,
85,
2226,
15,
754,
369,
24628,
4361,
253,
3242,
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2715,
273,
253,
1067,
13,
533,
344,
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253,
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281,
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544,
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62,
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1806,
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15,
3435,
15,
187,
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1628,
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15,
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15,
309,
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779,
281,
4745,
17928,
432,
5759,
1754,
327,
436,
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187,
187,
18130,
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27,
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15,
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598,
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7827,
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15212,
629,
273,
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1078,
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275,
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3778,
858,
417,
1333,
13,
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344,
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13730,
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25613,
15,
187,
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6802,
15,
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2506,
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15,
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24628,
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3242,
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2715,
273,
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1067,
13,
533,
344,
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253,
3000,
281,
1056,
352,
19639,
1905,
10053,
500,
15,
3778,
12626,
6549,
16008,
18130,
10,
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3435,
13,
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187,
187,
19639,
27962,
19201,
13,
271,
479,
3590,
8106,
15,
10197,
22250,
20955,
10810,
4966,
4889,
10197,
48983,
6582,
18591,
5324,
15,
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1648,
3103,
27786,
281,
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9919,
281,
809,
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15,
754,
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1107,
15,
309,
717,
6789,
323,
779,
281,
4745,
17928,
432,
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2,
1905,
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32050,
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13,
581,
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273,
253,
7422,
14,
18130,
3007,
2035,
3762,
13,
323,
8067,
839,
11821,
273,
253,
7045,
15,
187,
187,
1628,
6175,
253,
16782,
369,
8288,
309,
574,
3095,
2505,
479,
13,
2802,
261,
344,
816,
2403,
436,
598,
29200,
668,
2719,
10035,
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313,
51,
14,
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10,
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15,
773,
1898,
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13,
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344,
369,
15,
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310,
1805,
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253,
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3000,
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] |
Hell, I’ll still be a big WIMP supporter. But my priorities have to change… As I approach my 30’s, I want to spend more time with my family and friends. I also want to think about building a family of my own.
And WIMP is growing up. What WIMP needs now is different from what it needed to get started. While I’ve got some skills, I’m no CEO — I learned that the hard way with my startup, Bluebird.
In closing, I just want to say thank you. Thank you for the support. For the creativity. For the love. I’m sure I’ll see you around.
Wimptator emeritus,
Josh Simmons
This was cross-posted from Josh's original blog post for Web & Interactive Media Professionals: "Life After Wimptator."
I've been interviewed many times, this was my first time on the other side of the table! It was a great experience and it went well, though I've learned not to wear white on video and to stick to nonverbal cues when the interviewee is speaking.
In this, I speak with Marcia Reifer Johnston and Eric Holscher, organizer of Write the Docs, a conference that's bringing technical writers and documentation practices into the 21st century while promoting awareness of the need to doc.Enhancing factor, a Paneth cell specific protein from mouse small intestines: predicted amino acid sequence from RT-PCR amplified cDNA and its expression.
Enhancing factor (EF), a Paneth cell specific growth factor modulator, has been identified in our laboratory from mouse small intestines. In this paper we describe generation of an EF specific cDNA by RT-PCR and its sequence. The predicted amino acid sequence was found to be similar to, and hence confirms, the partial amino acid sequence obtained earlier by protein sequencing. In Northern blot analysis, a 1 kb transcript was observed in intestinal RNA alone. In situ hybridization indicated that the EF gene is expressed exclusively in the Paneth cells. The present study indicates that EF is an isoform of PLA2 type II, with a unique tissue distribution, found predominantly in the Paneth cells of the small intestines. Further, based on the properties of EF, we propose that isoforms of PLA2, belonging to type II, may be involved in regulation of cell proliferation via EGF binding.Is the farm wheelchair accessible?
Q - Is the farm wheelchair accessible?
A - We have a paved driveway for parking, and we have a level deck for viewing on the side of the store. However, this is a farm. Unfortunately, since this is a working farm we cannot accommodate all persons of disability. The earth is quite uneven and not level, there are many holes and divots from being a farm. If you choose to peruse the farm for closer viewing pleasure, you will do so at your own risk.Cholate and pH reduce interference by sodium dodecyl sulfate in the determination of DNA with Hoechst.
The use of the fluorescent dye 33258 Hoechst (Hoe) to quantitatively determine DNA in cell culture in the presence of lysing agents like sodium dodecyl sulfate (SDS) is limited by the masking effect of high levels of nonspecific fluorescence, caused by the binding of Hoe to micelles. The masking effect can be reduced substantially by increasing the concentration of the counterion, the addition of cholate, or the pH of the buffer. An optimized method was developed, combining the antimasking effects of sodium chloride, cholate, and pH to accurately determine DNA concentrations as low as 15 ng/ml in the presence of up to 6.9 mM (0.2%) SDS. The effectiveness of SDS in cell dissolution can now be combined with the specificity and sensitivity of Hoe to determine cellular DNA.Good Men and Monsters
AFTER THE NEBULA AND HUGO, THE PROMETHEUS Award is one of the oldest and most enduring fan-based awards in Science Fiction. Established in 1979, the award has been presented annually since 1982 at the World Science Fiction Convention. Nominees must dramatize the conflict between individuals and coercive governments, champion human rights, promote personal and economic liberty, explore a free future, or critique the tragic consequences of abuse of power, especially by the State. Sarah Hoyt’s “Darkship Thieves” won the 2011 Prometheus Award in Reno, and “A Few Good Men,” the third novel in this series, has been short-listed for the 2014 Hugo in London.
On the dystopian Earth of this novel, the ruling party—inaptly known as The Good Men—are killing millions with carefully engineered “natural” disasters. Homosexuality is a crime. The son of the Good Man of Olympic Seacity is barely holding onto his sanity after…
2 responses to ““A Few Good Men” by Sarah Hoyt (Perihelion review, May 2014)”
John, it certainly is an interesting novel. The leading man is gay. His best friend is gay. Gotta wait for the sequel to see where this is gonna go. 🙂 The opening page is marvelous. Thx for reblogging![Clinical aspects of Behçet's disease--epidemiological features and visual prognosis].
Behçet's disease patients who visited the eye clinic of Tokyo University Hospital during the past 20 years were surveyed retrospectively, and their epidemiological features and visual prognosis were demonstrated. We evaluated the number of patients, sex ratio, age of onset, ratio of complete type to incomplete type, and ratio of major symptoms other than the ocular manifestation. The results showed a tendency similar to the results of the nationwide hospital survey in Japan. We also evaluated the visual prognosis of Behçet's disease patients in our clinic by the least square method. In the groups of patients whose visual acuity at the initial visit was over 0.4, the visual prognosis of those who visited from 1984 till 1993 was significantly better than that of those who visited from 1974 till 1983. The use of cyclosporine was presumed to be one of the most important factors in the improved visual prognosis of Behçet's disease patients in our clinic.(L)-Committee chairman Rep. Adam Schiff (D-Calif.) delivers opening remarks at a hearing featuring Acting Director of National Intelligence Joseph Maguire testifying before the House Select Committee on Intelligence in the Rayburn House Office Building on Capitol Hill in Washington on Sept. 26, 2019. (Alex Wong/Getty Images) (R)-President Donald Trump speaks to the media at the United Nations in New York on Sept. 24, 2019. (Spencer Platt/Getty Images)
President Trump: Adam Schiff ‘Lied to Congress,’ Should Resign
President Donald Trump alleged that Rep. Adam Schiff (D-Calif.) “lied to Congress” when the representative fabricated parts of the released transcript of the call between Trump and Ukranian President Volodymyr Zelensky.
“Rep. Adam Schiff fraudulently read to Congress, with millions of people watching, a version of my conversation with the President of Ukraine that doesn’t exist. He was supposedly reading the exact transcribed version of the call, but he completely changed the words to make it sound horrible [and] me sound guilty,” Trump said in a statement early Sept. 27.
“HE WAS DESPERATE AND HE GOT CAUGHT. Adam Schiff therefore lied to Congress and attempted to defraud the American Public. He has been doing this for two years. I am calling for him to immediately resign from Congress based on this fraud!”
Trump later added: “Rep. Adam Schiff totally made up my conversation with Ukraine President and read it to Congress and Millions. He must resign and be investigated. He has been doing this for two years. He is a sick man!”
Schiff, the chairman of the House Intelligence Committee, added words to the transcript while appearing to read from it during opening remarks at a committee hearing on Thursday. Schiff quoted part of the transcript before mixing in words Trump did not say, later claiming he did it partly in jest.
Rep. Adam Schiff fraudulently read to Congress, with millions of people watching, a version of my conversation with the President of Ukraine that doesn’t exist. He was supposedly reading the exact transcribed version of the call, but he completely changed the words to make it…. — Donald J. Trump (@realDonaldTrump) September 27, 2019
….sound horrible, an me sound guilty. HE WAS DESPERATE AND HE GOT CAUGHT. Adam Schiff therefore lied to Congress and attempted to defraud the American Public. He has been doing this for two years. I am calling for him to immediately resign from Congress based on this fraud! — Donald J. Trump (@realDonaldTrump) September 27, 2019
Republicans on the committee castigated Schiff, one of the leading proponents of the Russia-Trump collusion theory, for fabricating portions of the transcript.
“While the chairman was speaking I had someone text me, ‘is he just making this up?’” Rep Mike Turner (R-Ohio) said. “And yes, yes he was. Because sometimes fiction is better than the actual words or the text. But luckily the American public are smart and they have the transcript. They’ve read the conversation, they know when someone’s just making it up.”
Schiff later told those assembled: “My colleague is right … it’s not okay. But also my summary of the president’s call was meant to be, at least part, in parody. The fact that that’s not clear is a separate problem in and of itself. Of course, the president never said ‘if you don’t understand me
|
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all the many other social websites. To get more information on Darrem Charles and Frank Fielding, visit their wiki pages to get instant access to all their promotional work and talents.1. Field of the Invention
The present invention relates to an infant feeding device that closely approximates natural breast feeding in the sensory experiences provided to the baby and promotes parent-baby bonding 1) mechanically, as the feeding container simulates a breast in its fluid delivery, shape, texture, feel, and ease of infant attachment for suckling, and 2) psychologically, as the nurser is designed to permit both the infant and the parent to assume a natural position where the infant can feel the body heat and heartbeat of the parent, the parent""s hands are free to cuddle the infant during feeding, and the infant""s face is pressed against the nipple to stimulate the perioral area and imitate a breast.
One of the largest shortcomings of conventional baby bottles and modern nursers with improved shapes is that the devices do not provide the full maternal benefits that are a necessary part of maximizing sustenance to the child, both physically and psychologically. Even recently engineered feeding containers that deliver more fluid with less air are typically advanced as baby bottle substitutes to be used by an adult holding the bottle in one hand which is offered to an infant cradled by the the adult""s opposite arm and hand. Both the adult""s hands are devoted to feeding and not cuddling the infant, the infant is not positioned next to the chest area of the adult, and the infant""s face is not pushed against the nipple. Thus, important bonding opportunities that are inherent in the practice of breast feeding are not available with ordinary bottle feeding. This deprives infants cared for by their fathers or other men such as grandfathers, who now take an active role in child rearing in industrialized societies, or by non-nursing mothers, surrogate parents, and other infant caretakers, of the important positive bonding advantages obtained by infants who breast feed, and deprives the adults of significant bonding experiences with the infant. This invention addresses these concerns.
2. Description of Related Art
Myriad vessels with nipples, pap boats, and other nursing devices have been used for millenia for feeding infants as a substitute for breast feeding. In modern times, an elongated cylindrical bottle of glass or plastic, equipped with a cap and an enlongated latex nipple, became universally known and used as a conventional baby bottle. Only more recently have alternative feeding apparatuses been suggested as improvements over this basic design. These roughly fall into two groups: designs with a nipple that more closely approximate the shape of a human breast and designs that position the baby for feeding in a configuration more closely approximating that of an infant suckling from a breast.
In the former category, for example, Prentiss suggested an infant feeding container that was wider than a conventional baby bottle and had a nipple more closely approximating a breast-shape (U.S. Pat. No. 5,690,679; this and subsequent cited patents are expressly incorporated in their entireties by reference). This was said to more closely approximate the experience of natural breast feeding, and provide a bottle that was more stable for an older child to put down without tipping it over.
In U.S. Pat. No. 6,161,710, Dieringer and Suarez disclosed an improved natural nipple baby feeding apparatus which includes detachable inner and outer membranes which both extend substantially across a distance larger than the diameter of a standard baby bottle, providing a nipple surface more closely approximating a the areola of a human breast. The device was said to make it easier for a baby to xe2x80x9clatch onxe2x80x9d to in a manner similar to natural suckling of a breast, rather than sucking from an elongate smooth single rubber nipple of a conventional baby bottle, and hence, easier for the baby to alternate between breast feeding and bottle feeding. Prentiss suggested an infant feeding container in the overall shape of a breast, rather than just the nipple portion (U.S. Pat. No. 5,993,479). Holmquist provided a cushion under the nipple portion of a baby feeding apparatus and a spring-biased pressure plate to force a milk bag in the container portion toward the nipple as the milk level fell with the infant""s feeding (U.S. Pat. No. 5,947,427). Griffin even more closely approximated a human nipple by suggesting nipple manufacture using a device formed from a mold taken of the nursing mother""s breast so that the shape exactly replicated the mother""s nipple (U.S. Pat. No. 5,108,686).
In the latter category of designs directed to positioning the infant, Jones disclosed a surrogate nursing bib that secured around the neck and around the waist of the wearer, and held a milk pouch that protruded from either of two orifices in the bib located on the chest of the wearer at the wearer""s breast position (U.S. Pat. No. 5,086,517). Goldson and Goldson suggested a similar bib (U.S. Pat. No. 4,776,546). Beard and Beard suggested a nursing baby bottle holder that was a sling that could be draped around the neck of the person feeding the baby, which supported the baby bottle in a nursing position (U.S. Pat. No. 5,582,335).
It would be desirable to combine many of these desirable features with fluid delivery more closely approximating breast feeding to provide a baby nurser that more closely mimicks natural breast feeding and contributes to parent-infant bonding during feeding, and thus to the emotional stability of a healthy child.
These objectives and others are provided by the present invention which describes an infant nurser that has a container that closely simulates the sensation provided by a mother""s breast in its shape and fluid delivery and which is, in the preferred embodiment, attached to a shoulder sling and positioned over the breast of the person feeding the infant, leaving both arms free to caress the infant held in close proximity to the adult""s chest. In an alternate embodiment, the same advanced design container may be attached to a hand strap so the infant can be fed as if the nurser were an ordinary baby bottle.
The two embodiments are illustrated in FIGS. 1 and 12, more fully described below. Briefly, the container has two main parts: a flexible, dome-shaped housing approximately in the form of a human female breast and having a centrally positioned aperture in the apex region of the housing and a securing means in the base rim region opposite the apex for holding a pouch in the interior of the housing and releasibly attaching the container to a hand strap or shoulder sling, and a pouch that contains fluids and conforms to the housing interior when placed inside it and comprises a collapsible bag having a nipple which protrudes through the housing aperture and allows passage of fluids therethrough when an infant suckles on the nipple, and an attachment collar and lid which holds a flanged end of the bag opposite the nipple through which fluids may be poured to fill the bag and hold fluids in it. Typical securing straps that hold the pouch in the dome housing have hook and loop fasteners such as Velcro(trademark) so that the container can be easily emptied or filled by pulling apart the Velcro(trademark) and putting in or taking out the pouch (illustrated in FIGS. 2 and 4). The bag of the pouch is preferably disposable plastic that doesn""t need to be sterilized for repeated use, and the cap of the pouch has an attachment collar that holds and secures a flange on the bag and is threaded to receive a screw-on pouch lid (illustrated in FIGS. 5 to 7); the flange serves as a gasket, making the pouch leakproof when containing liquids and excluding air from the bag as the infant suckles.
The container is releasibly attached to either a hand strap or a shoulder sling. Preferred embodiments employing hook and loop fasteners, e.g., Velcro(trademark), are illustrated in FIGS. 3 and 11. Both have container attachment sites that present a hook fastener area so that the container can be easily attached or removed from the sling or hand strap by simply placing the container on a Velcro(trademark) patch on the sling or wrist strap and pulling it off. As mentioned above, in the preferred sling embodiment, the container attachment site is positioned over the breast of the person feeding the baby (FIG. 1). The hand strap embodiment positions the container attachment site in the palm area for convenience in feeding the infant by conventional means. In both cases, however, the suckling infant using a nurser of the invention has the benefit of of a feeding experience that simulates natural breast feeding in that the baby""s face is pressed up against the container (as illustrated in FIG. 13) and the internal pouch slowly deflates while the baby is held up against the chest of the nurturing adult.If everyone at your school watches South Park and your name is Kenny You're gonna have a bad time
254 sharesWater Tech
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|
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] |
342844726802016-09-21T12:59:10.401+10:002016-09-21T12:59:10.401+10:00Hi Helena, this book by Percy Trezise & Dick R...Hi Helena, this book by Percy Trezise & Dick Roughsey. It was published by a minor publisher in 1988 and I don't think it has been reprinted. It's not surprising that you can't get it in Australia when its not in print. That's where online sites like Amazon can help with second hand copies (NB the few new copies they have are over $100US). Trevor Trevor Cairneyhttps://www.blogger.com/profile/10743409298855125040noreply@blogger.comtag:blogger.com,1999:blog-9200808769555430311.post-72400733277347272432016-09-21T03:45:33.687+10:002016-09-21T03:45:33.687+10:00I live in Maine during the summer and Tucson, Ariz...I live in Maine during the summer and Tucson, Arizona in winter. My bird feeder customers are different in each locality. At this time of the year I mourn leaving the bluejays, nuthatches, chickadees, downey and hairy woodpeckers. Reading this blog today about the quail reminds me of what waits at my feeders in Arizona. I think of the Great Horned Owl triplets that were almost ready to leave the nest last April and my lucky chance to see one new Gambel quail family right before leaving. These birds are truly special to observe over their life cycle. The parenting behavior you wrote about is remarkable.<br /><br />I just ordered GQ, GQ, Where Are You to share with the children I teach in Tucson. Thanks for the gift of this title and for the reminder that when one door closes another opens! Anonymousnoreply@blogger.comtag:blogger.com,1999:blog-9200808769555430311.post-22739286562370942042016-09-20T18:21:46.264+10:002016-09-20T18:21:46.264+10:00A fellow collegue of mine asked me about a book he...A fellow collegue of mine asked me about a book he wanted to buy for his grandchild (non-Indigenous mate too) and it was an old aboriginal story telling one called Gidja. It just bought back a rush of memories from my childhoood growing up in QLD. Having read the Rainbow Serpent and the quinkin. I been googling where I can purchase these books to pass onto the next generations but don't seem to have any luck. I found the Gidga book but its coming from USA. Come on Australia its our history where can i buy locally???<br />Helenanoreply@blogger.comtag:blogger.com,1999:blog-9200808769555430311.post-60302217657043016012016-08-17T04:48:52.596+10:002016-08-17T04:48:52.596+10:00Hi Trevor!
I found this entry really interesting a...Hi Trevor!<br />I found this entry really interesting and exciting. Wow! My friend Sandy Fussell sent me your blog link and wrote, 'This man really knows his stuff.' I was excited to see 'this man' was you. It's been years since we met together, I think it was at Charles Sturt University Enrichment Studies. Nowadays I am a much-published author (http://www.enterprisingwords.com.au) and about to publish my first book under my About Kids Books imprint (http://www.aboutkidsbooks.com) It's All of Us Together by my husband of 34 years, Bill Condon who you might have heard of (winner of 3 CBCA Honor Books and PM Literary Award winner). We live in Wollongong NSW. My email address is dibates@outlook.com <br />Would love to hear from you! Di!www.aboutkidsbooks.comnoreply@blogger.comtag:blogger.com,1999:blog-9200808769555430311.post-79273243278821070742016-07-27T23:49:14.375+10:002016-07-27T23:49:14.375+10:00One of the most important issues of writing a high...One of the most important issues of writing a high-quality course works is picking an appropriate topic. It often poses a serious problem for students as they have little experience in this matter.<br />reading response sampleshttp://www.readingresponse.net/why-our-independent-reading-response-writers/noreply@blogger.comtag:blogger.com,1999:blog-9200808769555430311.post-15806606619771740562016-07-16T22:15:36.969+10:002016-07-16T22:15:36.969+10:00Thanks for this post, I'm going to try and get...Thanks for this post, I'm going to try and get a few of these booksAnonymousnoreply@blogger.comtag:blogger.com,1999:blog-9200808769555430311.post-41093931696151124522016-06-23T12:22:48.943+10:002016-06-23T12:22:48.943+10:00Yes, I've heard that but the book as a work sa...Yes, I've heard that but the book as a work says something quite different. I appreciate your perspective on this but suspect we'd be rejecting a lot of literature and art if we applied the same principle uniformly.Trevor Cairneyhttps://www.blogger.com/profile/10743409298855125040noreply@blogger.comtag:blogger.com,1999:blog-9200808769555430311.post-6990564931728164732016-06-23T08:31:46.663+10:002016-06-23T08:31:46.663+10:00Although The Sneeches fits this theme of understan...Although The Sneeches fits this theme of understanding others, I recently discovered that Dr. Seuss was a racist and no longer recommend his books. http://www.pragmaticmom.com/2016/04/dr-seuss-racist/ He's the pot calling the kettle black.PragmaticMomhttp://pragmaticmom.comnoreply@blogger.comtag:blogger.com,1999:blog-9200808769555430311.post-76503803043527921102016-06-14T11:49:16.486+10:002016-06-14T11:49:16.486+10:00Hi Puloma, thanks for your comment and question. I...Hi Puloma, thanks for your comment and question. If you look at the sidebar of this blog and click on the link to 'writing' the first few posts will offer plenty of suggestions. I hope that this helps. TrevorTrevor Cairneyhttps://www.blogger.com/profile/10743409298855125040noreply@blogger.comtag:blogger.com,1999:blog-9200808769555430311.post-45050917650830816002016-05-14T22:15:41.473+10:002016-05-14T22:15:41.473+10:00My daughter is 5 years old and still unable to rec...My daughter is 5 years old and still unable to recognize or write letters. She can write A that too after lot of coaxing. What should I do? "" Please guide. puloma banerjeehttps://www.blogger.com/profile/18401734125920209899noreply@blogger.comtag:blogger.com,1999:blog-9200808769555430311.post-84867880483044521582016-04-12T02:37:13.856+10:002016-04-12T02:37:13.856+10:00One of the most powerful ways to evoke my children...One of the most powerful ways to evoke my children’s childhood is through the books that we shared. When I turn the pages of these books (which of course I’ve kept – for my grandchildren!) memories of what my children did, said, liked or felt come flooding back. When my son started at nursery, our routine consisted of him choosing one book to be read to him before I went off to work. He chose the same book every day for the first six months! Wondering what he was still getting out of the experience after the umpteenth reading, I came to understand that the appeal was that he knew exactly what was going to happen and that reading the same book brought a comforting sense of structure to the day
|
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Yes We Can / Field Of Play / One World / Cooltide / Glory Box / Sweet Little Mystery
15 June 2000
Milton Keynes
The Stables
With John Giblin, Arran Ahmun, Spencer Cozens and Jim Lampi.
111
Aud
Feel So Good / How Fortunate The Man With None / Excuse Me Mister / Cry Me A River / Wildflower / Lookin On / So Sweet / / Shes A Lover / Solid Air / Rock Salt And Nails / Yes We Can / Field Of Play / One World / Cooltide / Glory Box / Johnny Too Bad
19 June 2000
Guildford
Civic Hall
With John Giblin, Arran Ahmun, Spencer Cozens and Jim Lampi.
96
Aud
Feel So Good / How Fortunate The Man With None / Excuse Me Mister / Cry Me A River / Wildflower / Lookin On / So Sweet / / Shes A Lover / Solid Air / Rock Salt And Nails / Yes We Can / Field Of Play / One World / Johnny Too Bad / Never Let Me Go / Sweet Little Mystery
22 June 2000
Shrewsbury
The Music Hall
With John Giblin, Arran Ahmun, Spencer Cozens and Jim Lampi.
92
Aud
Feel So Good / How Fortunate The Man With None / Excuse Me Mister / Cry Me A River / Wildflower / Lookin On / So Sweet / / Shes A Lover / Solid Air / Rock Salt And Nails / Yes We Can / Field Of Play / Johnny Too Bad / One World
24 June 2000
Glastonbury
Festival
With John Giblin, Arran Ahmun, Spencer Cozens and Jim Lampi.
29
Aud
Feel So Good / How Fortunate The Man With None / Excuse Me Mister / Lookin On
24 June 2000
BBC Radio
Radio 2 Richard Allinson Show, Interview from Glastonbury Festival
Solo
2
FM
Interview
26 June 2000
Glasgow
Renfrew Ferry
With John Giblin, Arran Ahmun, Spencer Cozens and Jim Lampi.
29 June 2000
Aberdeen
The Lemon Tree
With John Giblin, Arran Ahmun, Spencer Cozens and Jim Lampi.
93
Aud
Feel So Good / How Fortunate The Man With None / Excuse Me Mister / Cry Me A River / Lookin On / So Sweet / Shes A Lover / Solid Air / Rock Salt And Nails / Yes We Can / Field Of Play / Johnny Too Bad / Cooltide / Glory Box
24 January 2001
London
Jazz Café
With Arran Ahmun, Spencer Cozens and Alan Thomson
74
Aud
Man In The Station / Some People Are Crazy / Hole In The Rain / Baby Please Come Home / Carmine / Jack The Lad / Rope Sould / Cocain / Dont Want To Know / My Creator / Yes We Can / Small Town Talk / Cooltide
25 January 2001
London
Jazz Café
With Arran Ahmun, Spencer Cozens, Martin Winning and Alan Thomson
98
Aud
Man In The Station / Some People Are Crazy / Hole In The Rain / Baby Please Come Home / Carmine / Jack The Lad / Rope Sould / May You Never / Dont Want To Know / My Creator / Suzanne / Small Town Talk / Yes We Can / Cooltide / Lookin On / You Dont Know What Love Is
26 January 2001
Spalding
South Holland Centre
With Arran Ahmun, Spencer Cozens and Alan Thomson
82
Aud
Man In The Station / Some People Are Crazy / Hole In The Rain / Baby Please Come Home / Carmine / Jack The Lad / Dont Want To Know / My Creator / Suzanne / Small Town Talk / Yes We Can / Cooltide / You Dont Know What Love Is
30 January 2001
Croydon
Fairfield Halls
With Arran Ahmun, Spencer Cozens and Alan Thomson
19
Aud
Man In The Station / Some People Are Crazy / Hole In The Rain / Baby Please Come Home
Cooltide / Glorious Fool / Couldnt Love You More / Lookin On / Dreams by The Sea / Man In The Station / Over The Hill / Dont Want To Know / May You Never / Easy Blues / Gentle Blues / Id Rather Be The Devil / Go Down Easy / Solid air / Rock Salt And Nails / Never Let Me Go
Cooltide / Glorious Fool / Couldn’t Love You More / Lookin’ On / Dreams By The Sea / Man In The Station / Over The Hill / Don’t Want To Know / May You Never / Easy Blues / Gentle Blues / I’d Rather Be The Devil / Go Down Easy / Solid Air / Rock Salt And Nails / Never Let Me Go
3 February 2007
London
The Roundhouse
With Spencer Cozens, Arran Ahmun, Alan Thomson and Martin Winning
7
Aud
Rock Salt And Nails
30 May 2007
Croydon
Fairfield Halls
With Fos Patterson, Arran Ahmun, Alan Thomson and Martin Winning
81
Aud
Cooltide / Lookin On / Dreams by The Sea / Man In The Station / Over The Hill / Easy Blues / Gentle Blues / Dont Want To Know / May You Never / Id Rather Be The Devil / Go Down Easy / Solid air / Rock Salt And Nails / Never Let Me Go (Part)
1 June 2007
Liverpool
Philharmonic Hall
With Fos Patterson, Arran Ahmun, Alan Thomson and Martin Winning
76
Aud
Cooltide / Lookin On / Dreams by The Sea / Man In The Station / Over The Hill / Easy Blues / Gentle Blues / Dont Want To Know / May You Never / Id Rather Be The Devil / Go Down Easy / Solid air / Rock Salt And Nails / Never Let Me Go
Important Notice
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780 P.2d 1346 (1989)
Modesto MENDICOA, Appellant (Petitioner),
v.
The STATE of Wyoming, Appellee (Respondent).
No. 88-260.
Supreme Court of Wyoming.
October 2, 1989.
Michael D. Newman, Rock Springs, for petitioner.
Joseph B. Meyer, Atty. Gen., John W. Renneisen, Deputy Atty. Gen., and Karen A. Bryne, Sr. Asst. Atty. Gen., Cheyenne, for respondent.
Before CARDINE, C.J., and THOMAS, URBIGKIT, MACY and GOLDEN, JJ.
GOLDEN, Justice.
This appeal arises from a criminal action originally brought in Sweetwater County court. On a petition for review on certiorari from the county court, after an initial appeal to the district court, petitioner Modesto Mendicoa (Mendicoa) seeks reversals of his convictions on two counts of "importing" livestock into Wyoming without valid health certificates, in violation of W.S. XX-XX-XXX (1977), and the Governor's Livestock Import proclamation.
Mendicoa's issues are:
1. Did the District Court err in not ruling that W.S. XX-XX-XXX and the Governor's Livestock Import proclamation are unconstitutional in that the legislative branch has improperly delegated to the executive branch the authority to establish a new and distinct crime for shipping and transporting livestock through Wyoming to a destination in another state?
2. Did the District Court err in not finding that the Governor's Livestock Import proclamation was unconstitutional because it unlawfully burdened interstate commerce?
3. Did the District Court err in not finding that the trial court's instructions to the jury gave the impression that it is unlawful and a violation of W.S. XX-XX-XXX *1347 to ship, transport or move any livestock into or within the State of Wyoming unless the livestock are accompanied by an official health certificate in possession of the driver?
4. Did the District Court err in affirming the trial court's denial of Defendant's Motion for Acquittal concerning the weight, sufficiency and admissibility of the evidence presented at trial, notwithstanding the jury's verdict?
We reverse Mendicoa's convictions on the grounds
|
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mu_2=1.95\sqrt{m\epsilon}/\sigma^2$, where $m$ and $\epsilon$ are suitable mass and energy scales in the MD simulation. From now on we delete the units. The slip coefficient in the effective wall force is set to $\beta_S=1.2$. The surface tension is $\tau = 5.5$. The wall velocity, cf. Figure \[fig:CouetteFlow\], is $U_{wall}=0.25$. In this system a steady state is reached as illustrated in Fig. \[fig:couetteflow2\].
![The MD Couette flow setup in [@Qian03].[]{data-label="fig:couetteflow2"}](couette.jpg){width="80.00000%"}
The MD simulations provide velocity profiles, which will be compared with the numerical simulations by our finite element method. In our simulations we take the channel given by $(-L_x/2,L_x/2)\times(0,L_y)\times(0,L_z)$, and we use a periodic boundary condition in the $y$-direction. On the left and right boundary, we take Dirichlet boundary condition given by $\mbf u(y,z)=\frac{2U_{wall}(z-L_z/2)}{L_z+2*l_{s}}\mathbf{e}_1$, for $(y,z) \in (0,L_y) \times (0,L_z)$, where $l_{s}=\mu/\beta_S$ is the slip length. In this test, we take an initial tetrahedral triangulation with 11 vertices (10 intervals) on the edges of the channel in $x$-direction, 5 vertices (4 intervals) on the edges in $z$-direction an 3 vertices (2 interval) on the edges in $y$-direction, and we apply 3 adaptive refinements near the interface. Numerical results for the computed equilibrium solution are shown in Fig. \[fig:CompareMD\]. We show the profile of the relative velocity in $x$-direction $u_1/U_{wall}$, where $u_1$ denotes the $x$-component of velocity. The profiles are shown for $u_1(x,\frac12 L_y, z_j)$, with $x \in [-25,25]$, $z_1=0.425$ (green/bottom), $z_2=2.125$ (black), $z_3=3.825$ (blue) and $z_4=5.525$ (red/top). The empty symbols show the results from MD simulations and the filled symbols with solid lines show the results by our FEM method. We observe a good agreement between the two sets of simulation results. Note that differences may be due not only to numerics but also to modeling discrepancies. Near the wall boundary, at $z_1=0.425$ (bottom curve), the $x$-velocity $u_1(x,\frac12L_y, z_1)/U_{wall}$ is close zero for $x$ close to the contact line, which implies that the fluids slip there (note that the wall moves).
Wetting on a curved boundary
----------------------------
The following example demonstrates how our method performs for a contact line problem with a curved contact boundary. We solve a sliding droplet problem in a hemispherical domain. A droplet is set at the bottom of the hemisphere with a initial contact angle $\theta_0 = 104.5^\circ$. The rest of the domain is filled with another fluid. The density of the droplet is set to $\rho_1 = 3$ and the viscosity is $\mu_1 = 3$. The fluid outside has $\rho_2=1$ and $\mu_2 =1$. We ignore the effect of the gravity. The initial velocity is zero. We set the equilibrium contact angle $\theta_e=60^\circ$. Due to the difference between $\theta_0 $ and $\theta_e $, the droplet will spread on the bottom curved boundary and it is expected to reach a static state with a contact angle $\theta_d = \theta_e$. The spreading process and the static state are similar to the sliding droplet experiment in subsection 9.1. The only difference is that the contact boundary is curved.
In Figure \[fig:curvebnd\] we show a result of the dynamics of the droplet for $t=0.2$. In this simulation we use uniform grids with 16 intervals in each direction. The contour color denotes the velocity magnitude, and the white arrows represent the flow field. At the beginning stage $t=0.2$, a significant velocity, tangential to the curved boundary, appears in the vicinity of the contact lines. From the cross section result, we also observe that two vortices are formed. For larger $t$ ($t\approx 5$) the droplet becomes stationary and the contact angle is almost $60^\circ$. Table \[tab:curved\] shows results for the numerical contact angle and contact area at the static state. The experiment shows that Nitsche’s method can handle the Navier boundary condition on the curved boundary and results in an accurate approximation of the static state of a sliding droplet. In Nitsche’s method, for $\bn_S$ we used the normal to the piecewise planar approximation (faces of the tetrahedra) of the curved domain. We are aware of the fact that this choice for the normal may lead to a suboptimal discretization scheme, cf. [@urquiza2014weak; @Dione2015]. This is related to Babuska’s paradox [@verfurth1986]: the solution of stationary Stokes equations with slip boundary conditions on polygonal domains approximating the smooth domain do not converge to the solution of the smooth limit domain. A systematic investigation of this topic is left for future research.
$\theta_e$ $\theta_{e,h}$ $A$ $A_h$
------------ ---------------- ------- -------
60$^\circ$ 60.35$^\circ$ 0.055 0.054
: Comparison of analytical and discrete contact angle $\theta_e$ and contact area $A$.[]{data-label="tab:curved"}
![Wetting on a curved boundary.[]{data-label="fig:curvebnd"}](CurvedR3Ref2Step1.png)
Wetting on chemically boundary
------------------------------
In the last example, we present numerical results for a liquid droplet sliding on a chemically patterned surface. In this problem, due to the inhomogeneity of the solid surface, we have a more challenging contact line dynamics. A real three dimensional simulation is required to capture all the characteristics of the hydrodynamics.
In our example, the bottom $x-z$ surface is not homogeneous with a spatially varying static contact angle $\theta_e(x, z)$. In polar coordinates $(x,z)=(r\cos\phi, r\sin\phi)$ the prescribed static contact angles is $$\theta_e(r,\phi)=
\left\{\begin{array}{ll}
\frac{\pi}{3} & \hbox{if } \phi\in(0,\frac{\pi}{3})\cup(\frac{2\pi}{3},\pi)\cup(\frac{4\pi}{3},\frac{5\pi}{3}),\\
\frac{2\pi}{3} & \hbox{otherwise.}
\end{array}
\right.$$ In this setting, the surface contains both hydrophilic ($\theta_e < \frac{\pi}{2}$) and hydrophobic ($\theta_e > \frac{\pi}{2}$) parts.
A spherical droplet is placed at the center of the bottom plane. All other conditions are the same as in subsection 9.1. Figure \[fig:patterned\] shows some typical shapes of the droplet in the process of wetting. Starting with a uniform contact angle $\theta=\frac{\pi}{2}$ the droplet moves on the surface and changes its shape. It spreads on the hydrophilic part of the bottom and shrinks on the hydrophobic part. At $t=1.2$ the droplet is almost stationary. The contact angle then is approximately $60^o$ on the hydrophilic part of the surface and approximately $120^o$ on the hydrophobic part, away from boundaries between the two parts. The discrete contact angles, which are average values on a segment of the contact line away from the boundaries between the hydrophilic and hydrophobic parts, are shown in Table \[tab:patterned\] with the same resolution as the level 1 mesh in subsection 9.1. The results in this experiment show that our finite element approach is robust in the sense that in can also deal with this more complicated moving contact line flow problem.\
$\theta_A$ $\theta_{A,h}$ $\theta_B$ $\theta_{B,h}$
------------ ---------------- ------------- ----------------
60$^\circ$ 60.36$^\circ$ 120$^\circ$ 119.32$^\circ$
: Comparison of discrete contact angles and the prescribed Young’s angles in patterned surface. $\theta_A$ denotes the hydrophilic angle and $\theta_B$ denotes the hydrophobic angle.[]{data-label="tab:patterned"}
Conclusion and outlook {#sectoutlook}
======================
We presented finite element techniques for the discretization of two-phase flow problems with moving contact lines. For describing these flow problems a class of models is given and a corresponding variational formulation, which forms the basis for the finite element method, is derived. The stabilized XFEM method, recently introduced in [@Hansbo14] for a stationary two-phase Stokes problem
|
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] |
treatment of rare diseases with high unmet medical need. We are developing revusiran (ALN-TTRsc), a subcutaneously administered RNAi therapeutic for the treatment of hATTR-CM.
Revusiran for the Treatment of hATTR-CM
ENDEAVOUR Phase 3 Trial
In 2012, Alnylam entered into an exclusive alliance with Genzyme, a Sanofi company, to develop and commercialize RNAi therapeutics, including patisiran and revusiran, for the treatment of ATTR amyloidosis in Japan and the broader Asian-Pacific region. In early 2014, this relationship was extended as a broader alliance to advance RNAi therapeutics as genetic medicines. Under this new agreement, Alnylam and Genzyme have agreed to co-develop and co-commercialize revusiran in North America and Europe, with Genzyme developing and commercializing the product in the rest of world. This broadened relationship on revusiran is aimed at expanding and accelerating the product’s global value.
We presented pre-clinical data with ALN-TTRsc02, an investigational RNAi therapeutic targeting transthyretin (TTR) for the treatment of TTR-mediated amyloidosis (ATTR amyloidosis). In pre-clinical studies, including those in non-human primates (NHPs), ALN-TTRsc02 achieved potent and highly durable knockdown of serum TTR of up to 99% with multi-month durability achieved after just a single dose, supportive of a potentially once quarterly dose regimen. Results from studies comparing TTR knockdown activity of ALN-TTRsc02 to that of revusiran showed that ALN-TTRsc02 has a markedly superior TTR knockdown profile. Further, in initial rat toxicology studies, ALN-TTRsc02 was found to be generally well tolerated with no significant adverse events at doses as high as 100 mg/kg.
Heart failure with a preserved ejection fraction (HFPEF) is a clinical syndrome that has no pharmacologic therapies approved for this use to date. In light of failed medicines, cardiologists have refocused treatment strategies based on the theory that HFPEF is a heterogeneous clinical syndrome with different etiologies. Classification of HFPEF according to etiologic subtype may, therefore, identify cohorts with treatable pathophysiologic mechanisms and may ultimately pave the way forward for developing meaningful HFPEF therapies.1
A wealth of data now indicates that amyloid infiltration is an important mechanism underlying HFPEF. Inherited mutations in transthyretin cardiac amyloidosis (ATTRm) or the aging process in wild-type disease (ATTRwt) cause destabilization of the transthyretin (TTR) protein into monomers or oligomers, which aggregate into amyloid fibrils. These insoluble fibrils accumulate in the myocardium and result in diastolic dysfunction, restrictive cardiomyopathy, and eventual congestive heart failure (Figure 1). In an autopsy study of HFPEF patients, almost 20% without antemortem suspicion of amyloid had left ventricular (LV) TTR amyloid deposition.2 Even more resounding evidence for the contribution of TTR amyloid to HFPEF was a study in which 120 hospitalized HFPEF patients with LV wall thickness ≥12 mm underwent technetium-99m 3,3-diphosphono-1,2-propranodicarboxylic acid (99mTc-DPD) cardiac imaging,3,4 a bone isotope known to have high sensitivity and specificity for diagnosing TTR cardiac amyloidosis.5,6 Moderate-to-severe myocardial uptake indicative of TTR cardiac amyloid deposition was detected in 13.3% of HFPEF patients who did not have TTR gene mutations. Therefore, TTR cardiac amyloid deposition, especially in older adults, is not rare, can be easily identified, and may contribute to the underlying pathophysiology of HFPEF.
Figure 1
As no U.S. Food and Drug Administration-approved drugs are currently available for the treatment of HFPEF or TTR cardiac amyloidosis, the development of medications that attenuate or prevent TTR-mediated organ toxicity has emerged as an important therapeutic goal. Over the past decade, a host of therapies and therapeutic drug classes have emerged in clinical trials (Table 1), and these may herald a new direction for treating HFPEF secondary to TTR amyloid.
Table 1
TTR Silencers (siRNA and Antisense Oligonucleotides)
siRNA
Ribonucleic acid interference (RNAi) has surfaced as an endogenous cellular mechanism for controlling gene expression. Small interfering RNAs (siRNAs) delivered into cells can disrupt the production of target proteins.7,8 A formulation of lipid nanoparticle and triantennary N-acetylgalactosamine (GalNAc) conjugate that delivers siRNAs to hepatocytes is currently in clinical trials.9 Prior research demonstrated these GalNAc-siRNA conjugates result in robust and durable knockdown of a variety of hepatocyte targets across multiple species and appear to be well suited for suppression of TTR gene expression and subsequent TTR protein production.
The TTR siRNA conjugated to GalNAc, ALN-TTRSc, is now under active investigation as a subcutaneous injection in phase 3 clinical trials in patients with TTR cardiac amyloidosis.10 Prior phase 2 results demonstrated that ALN-TTRSc was generally well tolerated in patients with significant TTR disease burden and that it reduced both wild-type and mutant TTR gene expression by a mean of 87%. Harnessing RNAi technology appears to hold great promise for treating patients with TTR cardiac amyloidosis. The ability of ALN-TTRSc to lower both wild-type and mutant proteins may provide a major advantage over liver transplantation, which affects the production of only mutant protein and is further limited by donor shortage, cost, and need for immunosuppression.
Antisense Oligonucleotides
Antisense oligonucleotides (ASOs) are under clinical investigation for their ability to inhibit hepatic expression of amyloidogenic TTR protein. Currently, the ASO compound, ISIS-TTRRx, is under investigation in a phase 3 multicenter, randomized, double-blind, placebo-controlled clinical trial in patients with familial amyloid polyneuropathy (FAP).11 The primary objective is to evaluate its efficacy as measured by change in neuropathy from baseline relative to placebo. Secondary measures will evaluate quality of life (QOL), modified body mass index (mBMI) by albumin, and pharmacodynamic effects on retinol binding protein. Exploratory objectives in a subset of patients with LV wall thickness ≥13 mm without a history of persistent hypertension will examine echocardiographic parameters, N-terminal pro–B-type natriuretic peptide (NT-proBNP), and polyneuropathy disability score relative to placebo. These data will facilitate analysis of the effect of antisense oligonucleotide-mediated TTR suppression on the TTR cardiac phenotype with a phase 3 trial anticipated to begin enrollment in 2016.
TTR Stabilizers (Diflunisal, Tafamidis)
Diflunisal
Several TTR-stabilizing agents are in various stages of clinical trials. Diflunisal, a traditionally used and generically available nonsteroidal anti-inflammatory drug (NSAID), binds and stabilizes familial TTR variants against acid-mediated fibril formation in vitro and is now in human clinical trials.12,13 The use of diflunisal in patients with TTR cardiac amyloidosis is controversial given complication of chronic inhibition of cyclooxygenase (COX) enzymes, including gastrointestinal bleeding, renal dysfunction, fluid retention, and hypertension that may precipitate or exacerbate heart failure in vulnerable individuals.14-17 In TTR cardiac amyloidosis, an open-label cohort study suggested that low-dose diflunisal with careful monitoring along with a prophylactic proton pump inhibitor could be safely administered to compensated patients.18 An association was observed, however, between chronic diflunisal use and adverse changes in renal function suggesting that advanced kidney disease may be prohibitive in diflunisal therapy.In FAP patients with peripheral or autonomic neuropathy randomized to diflunisal or placebo, diflunisal slowed progression of neurologic impairment and preserved QOL over two years of follow-up.19 Echocardiography demonstrated cardiac involvement in approximately 50% of patients.20 Longer-term safety and efficacy data over an average 38 ± 31 months in 40 Japanese patients with hereditary ATTR amyloidosis who were not candidates for liver transplantation showed that diflunisal was mostly well tolerated.12 The authors cautioned the need for attentive monitoring of renal function and blood cell counts. Larger multicenter collaborations are needed to determine diflunisal’s true efficacy in HFPEF patients with TTR cardiac amyloidosis.
Tafamidis
Tafamidis is under active investigation as a novel compound that binds to the thyroxine-binding sites of the TTR tetramer, inhibiting its dissociation into monomers and blocking the rate-limiting step in the TTR amyloidogenesis cascade.21 The TTR compound was shown in an 18-month double-blind, placebo-controlled trial to slow progression of neurologic symptoms in patients with early-stage ATTRm due to the V30M mutation.22 When focusing on cardiomyopathy in a phase 2, open-label trial, tafamidis also appeared to effectively stabilize TTR tetramers in non-V30M variants, wild-type and V122I, as well as biochemical and echocardiographic parameters.23,24 Preliminary data suggests that clinically stabilized patients had shorter disease duration, lower cardiac biomarkers, less myocardial thickening, and higher EF than those who were not stabilized, suggesting early institution of therapy may be beneficial. A phase 3 trial has completed enrollment
|
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glass, like butterflies, with only a single spread to give any sense of what lies inside. Some of the exhibits in Blood on Paper are books more in concept than practice, such as Anselm Kiefer's free-standing lead book (The Secret Life of Plants, 2008), or Damien Hirst's elaborate cabinets (New Religion, 2005). But the books in show in the Photography gallery were intended by their makers to be held in the hand.
This tiny show is carefully chosen and clearly annotated, moving from Ana Atkins's British Ferns, made around 1852, to recent works such as Stephen Gill's Buried and Nigel Shafran's RuthBook - a photograph from which, London W10, February 1994, from RuthBook, 1995, Nigel Shafran, is pictured on this blog - both examples of small, self-published editions by British photographers. In some cases, a print by the same photographer is hung above the corresponding book in its glass case. But the invitation to "consider the difference between experiencing photographs as framed objects and on the pages of books" is somewhat disingenuous, since, exhibited this way, the book is pretty much forced into the same inertia as the print.
At a time when photography books are being, rightly, recognised for their importance, there is interest in photography books from all directions: the student, the public, the collector, the dealer, the publisher, the photographer. What a great exhibition could have been had here. And the V&A wouldn't have to go far for its contents. The National Art Library, one of the glories of the museum, holds at least one copy of almost every photographic book ever published. With more imagination and more space, the museum could have had a spectacular show of what it already has in its stacks.
The growing interest in photographic books was signalled in 2001 with the publication of Andrew Roth's The Book of 101 Books: Seminal Photographic Books of the Twentieth Century. In 2004 and 2006, Martin Parr and Gerry Badger's two volumes of The Photo Book: A History followed. The V&A might have exhibited its own top 100, and demonstrated its ingenuity by showing them in different ways. Now that digital scanning has made it possible for whole books to be made available online - such as Paul Fusco's Robert Kennedy Funeral Train (you can watch a film here) - some pages, particularly of the very valuable or fragile books, could have been shown electronically. And with many contemporary photography books still affordable, and in print, the gallery could have made a number of copies available so that visitors could have looked through them for themselves - or the publishers would surely have supplied them. They could even have built a library of selected books, where visitors could browse, as they are doing at Site, part of the John Moores University School of Art and Design in Liverpool, where the American artist Martha Rosler's personal library is installed until June as part of its international tour. Visitors can pull out the books and photocopy any of their pages for reference.
Instead, this small show is to stay up for a whole year, and visitors are directed to the National Art Library and the Prints and Drawings Study room, to request any books they would like to look at. The National Art Library is invaluable for anybody who wants to know more about photographic books. The NAL catalogue is now available online, and you can search and order up to six titles 48 hours in advance of your visit. But if you make your request in person, prepare to wait. You will possibly need a reader's ticket, which means authorisation and a delay of several days. The book might be out already. But the surroundings are gracious, and once delivered, the chance to spend a long time studying a book you've always wanted to look at, but which has become too rare or too expensive to acquire, is very satisfying.
When it comes to other specialist photographic libraries, there isn't much choice. The Photographers' Gallery Library was closed years ago. The Insight research room at the Media Museum in Bradford has a very limited number of general photographic books on display. London would benefit hugely from the kind of photographic library found in Paris, at the Maison Européene de la Photographie, where, if you simply leave some form of ID at the desk, you can call up one of their collection of around 21,000 photographic and photography-related books, or find back issues of photographic magazines, and spend the afternoon in comfort, looking through them. It was here that I first laid hands on some of the rare photography books that it was (and still is) impossible either to find or to buy.
The history of photography lies in its books. There is no better resource for understanding it. And despite the advantages brought by online databases and the invitation to "Search Inside!" there is no substitute for turning the pages of the real thing.
For information about access to the National Art Library and the Prints and Drawings Study Room go to vam.ac.uk
Blogspot 5B4
One of the very best photoblogs, particularly for lovers of photography books, is the 5B4 Photography and Books blog regularly posted by the mysterious Mr Whiskets. I say mysterious, but some time ago, the America photographer Alec Soth, another of Mr Whiskets's admirers, decided to track him down, and eventually identified him as the Brooklyn-based photographer Jeffrey Ladd. Apart from writing a really excellent, balanced commentary on current photography shows, books, trends, the market, and attendant matters, he also recommends and sources books. Now, he has added a new strand to his blog, the 5B4 Photobook Exchange, which is, as he explains, "created to match up neglected photo and art books with new and loving owners." He posts a list of available books, some of which come from his own collection, which include signed copies, rare collectors' items, or books he thinks deserve renewed attention, and readers can email him with an offer on the price.
Photograph above: A detail from Nigel Shafran's London W10, February 1994, from RuthBook, 1995
zondag 29 juni 2008
Lies Wiegmanwas active in several branches of photography: reportage, commercial and free work.
From 1946 to 1949 she attended a course in advertising and photography at the Royal Academy of Arts in The Hague, where her teachers were Gerrit Kiljan, Paul Schuitema and Gerard de Vries.
She began taking photographs in 1951 in Paris, where she spent a few years studying scenic design at the Ecole Paul Colin. In 1952 she went to New York. It is there that she took up photography in earnest, working nights and taking pictures during the day. She could print her photographs at the Village Camera Club, an inspiring place frequented by such photographers as Lisette Model, Cornell Capa, Eugene Smithand Robert Frank.When her tourist visa expired in 1955 she came back to the Netherlands. She earned her living as a photographer and travelled to Central and South America.
In 1962 she published her first children's book, Mijn Lama. It was followed in 1971 by another book for children, De eerste dag(the first day). Her third and last book was Bewaar het land(preserve the land), inspired by a speech delivered by the Indian chief Seattle in 1855 when his homeland was handed over to the white governor Stevens. The book was published in 1980 to mark the 75th anniversary of the founding of the Association of Nature Monuments.
From 1969 to 1986 Lies Wiegman taught at the School of Photography in The Hague. After her retirement she moved to San Miguel de Allende in Mexico. Her interest in photography has gradually shifted towards video and especially sculpture.
When the boys and girls of the Left Bank went on the pull in the 1950s, Ed Van der Elsken was there to record it, read more... & see also Ed van der Elsken Paris(with a young Brigitte Bardot)... & Paris Mortel...
Van der Keuken(1938) moved from Amsterdam to Paris in 1956 to study at the School of Film, the Institute des Hautes Etudes Cinématographiques (Idhec). He was confronted in Paris with life and man's loneliness living in a metropolis. Van der Keuken took thousands of photographs, the city acting as a background to his feelings of desolation. In 1963 a selection of these registrations were published in the book "Paris Mortel," a title that reflects the gloomy undertone of the contents of the book. In this book, Van der Keuken attempted to reflect the complexity of the city. As well as being a photographer, Van der Keuken is also a film maker, but seldom practises both media at the same time. His photography was a breeding ground for his film-making and functions as a "holiday from film making". His films became more and more socially critic in due course, an involvement that had already become apparent in the photo series "Paris Mortel."
Lies Wiegmanwas active in several branches of photography: reportage, commercial and free work.
From 1946 to 1949 she attended a course in advertising and photography at the Royal Academy of Arts in The Hague, where her teachers were Gerrit Kiljan, Paul Schuitema and Gerard de Vries.
She began taking photographs in 1951 in Paris, where she spent a few years studying scenic design at the Ecole Paul Colin. In 1952 she went to New York. It is there that she took up photography in earnest, working nights and taking pictures during the day. She could print her photographs at the Village Camera Club, an inspiring place frequented by
|
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15
] |
thought for sure Julia would make him forget about that other girl. Oh well.
Cockney housemaid: If you ain’t aiming too high, I know plenty of places where you can get a job like mine. [Julia looks distressed at the notion of being a maid.] But I suppose a fine lady like you was trained for something better.
JuliaRoss, looking stricken:The doctor says I’ve got to be careful for a few months.
Maid: Oh. My sister had her “appendix” out, too. She were scrubbing and cleaning the very next week.
Julia: Does it bother her now?
Maid: Nothing bothers her now. She’s dead. But it wasn’t good, honest work that killed her.
Now, tell me: is this a coded conversation about an abortion? Sure sounds that way to me.
16 March 2013
Here’s what I’d like to see.
Washington, D. C., 12:55pm:
Within hours of Sen. Rob Portman (R-OH) announcing that he had reversed his position on gay marriage after his own son came out of the closet, Sen. Ted Cruz (R-TX) gave a press conference announcing a new stance on abortion.
“During my career in Texas and my first coupla months here in the Senate, I’ve taken a position against abortion, rooted in part in my faith and my faith tradition, and also because the ladies can be selfish and irresponsible,” Cruz began. A senator known for his extreme far-right views (called by some of his GOP colleagues to be “wacko, but in a good way”), Cruz stunned his own caucus with his revelation:
I listened to my colleague talk about his change of heart after learning that his own son was gay, and I was very moved by his Christian love for his child. I’m sure we were all moved.
But then I thought, why is it that so many of my colleagues only change their minds about social issues when it strikes their own family?
So I began reading about the issue of abortion and realized that approximately 1/3 of all American women have had abortions in their lifetimes, and that 1 out of 5 women is raped in her lifetime. I read about families destroyed when a woman died during pregnancy because she felt morally obligated to carry the child. And I realized the simple contradiction between my firm belief in smaller government, and my insistence on monitoring women’s bodies regarding abortion and birth control.
Thus, I change my position today not because someone in my family needs an abortion, but because my entire position was wrong and morally inconsistent with my own political values in this great nation.
Well, you can’t blame me for wishing, right?
Don’t get me wrong: it’s great Portman changed his mind. But dammit, why do they only change position when suddenly their own family has a need? I’m sorry, folks, but this should not be how policy works.
17 February 2013
Only one more week before Oscar night, but who cares about that charade when there are the La Jefitas to think about? For the second year now I’ve compiled my list of the best 2012 films by and about women to celebrate those female bosses. It’s just one way I seek to subvert a male-dominated and sexist film industry. Because who cares about that Hollywood red carpet when you can enjoy an anonymous, verbose film blogger’s Best Of list?
Oh yeah, baby!
Unlike the flagrantly biased Oscars, the La Jefitas are selected with scientific precision; and although each year we have a select number of categories (Most Feminist Film; Best Female-Directed Film; Best Fight Scene in Which a Woman Kicks a Man’s Ass) we also add or tweak other categories to suit that year’s selections.
Shall we? Let’s start with a big one:
Best Actress:
Anna Paquin in Kenneth Lonergan’s Margaret. No matter how ambivalent you may feel about Paquin’s earning paychecks with fodder like True Blood (the later seasons, anyway) and the X-Men franchise, you can’t deny the force-of-nature bravura she displays in this extraordinary film. Replacing the saccharine Southern accent she put on in those other productions, she appears here with a kind of nervous mania that suits the particular cocktail of high school, trauma, selfishness, and guilt cooked up by this girl. When I wrote about it last spring, I called Paquin’s character an “asshole” — it’s hard, even now, for me to back away from that harsh term, for she has truly channeled the kind of chatterbox/ smartypants self-absorption and avoidance so crystalline in privileged teenaged girls. She captures it perfectly, and her particular vein of assholery is crucial to a film that wants us to think about the wake we leave behind us as we stride through the world.
Paquin won Best Actress, yet I have so many honorary mentions. I’ll narrow it down to two: Rachel Weisz in The Deep Blue Sea and Nadezhda Markina in Elena — two eloquent drawing room dramas that rely on perfectly-drawn portrayals by their female leads.
Female-Oriented Scene I Never Expected to See Onscreen (extra points for its political riskiness):
The abortion scene in Prometheus. Seriously? The film displayed such a strangely negative view of parenthood overall — indeed, I wondered in my long conversation with film blogger JustMeMike whether the film’s major theme was patricide — that in retrospect one was left shaking one’s head at all of Ridley Scott’s madness. And still, I return to the abortion scene. Wow — in this day and age, with abortion politics as insane as they are — did we actually witness an abortion in a major Hollywood release?
Yes, I know she was trying to abort an evil monster/human parasite/amalgam; but I’ll bet there are 34 senators in the U.S. Senate who would argue it was God’s plan that she bring that evil monster baby to term.
Best Fight Scene in Which a Woman Kicks a Man’s Ass:
Gina Carano has no competition this year after her performance in Steven Soderbergh’s Haywire. I know, I can’t remember the plot either; nor can I remember how it ended. And no, I’m not going to talk about the dialogue, or Carano’s acting ability.
Rather, the entire film was a paean to Carano’s superiority in ass-whupping. It was a thing of beauty — starting with her takedown of Channing Tatum in the diner and reaching its crowning glory with teaching Michael Fassbender a lesson in the hotel room. Be still my heart. Who needs plot or dialogue when you’ve got a human tornado?
Most Depressingly Anti-Feminist Trend of the Year:
Where did all the parts for Black women go? The tiny dynamo Quvenzhané Wallis has ended up with a well-deserved nomination for Best Actress this year — for her work in Beasts of the Southern Wild, filmed when she was six years old — but people, no 6-yr-old can carry the experiences of Black women on her tiny little shoulders.
Sure, we all complained last year about The Help — really, Hollywood? you’re still giving Black women roles as maids? — but let’s not forget some of the other films last year, most notably (to me) Dee Rees’ Pariah. And although I’m not surprised to find an actress of Viola Davis’ age struggling to get good work onscreen, I want to register how utterly depressing it is to find a Black woman of her talent and stature not getting leading roles in great films.
One can argue that high-quality TV is making up for the dearth of great parts for Black women onscreen. Just think about Kerry Washington in Scandal, for example. But for the sake of the La Jefitas I’ve limited myself to film — and I want more non-white actors, dammit.
Most Feminist Trend in Film in 2012:
2012 was the Year of Fierce Girls. It doesn’t take much to call to mind the most obvious films, starting very much with Wallis in Beasts of the Southern Wild. To list a few:
Now, I will also say that with all these good parts going to awesome girls (some of them animated, however), I didn’t see as many terrific parts going to mature/ middle-aged women; but still, considering how deeply male-dominated children’s filmmaking is, this is a very positive trend indeed.
Helene Bergsholm in Norway’s Turn Me On, Dammit!
Best Breakthrough Performance by an Actress Known for Very Different Roles:
Jennifer Lawrence in Silver Linings Playbook. I have a big ol’ crush on Lawrence from her serious roles, but I’ll be the first to admit that she found herself getting the same part over & over — that fiercely independent teen girl who struggles against the Great Forces that make life so difficult (Winter’s Bone, X-Men: First Class, The Hunger Games). Comedy wouldn’t have struck me as Lawrence’s forte.
So count me impressed.
|
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] |
$n^{\varphi h}$. The resulting multiplication
on $H\times N$ is then given by $(h,n)(k,m) = (hk,n^km)$.
Likewise a semidirect product of two monoids $H$ and $N$ is the same as a
monoid homomorphism $\varphi: H\rightarrow \mathrm{End}(N)$. The multiplication
is given in the same way.
Now consider a functor $F: C\rightarrow \mathrm{Cat}$ (I ignore dualization,
so this correspond to an op-fibration) and suppose that
(1) $C$ is a monoid (i.e. has exactly one object $*$)
(2) The category $F(*)$ is also a monoid.
Because an endofunctor on $F(*)$ is the same as a monoid homomorphism, this
is the same as giving a monoid homomorphism from $C$ to $\mathrm{End}(F(*))$.
In fact, if you go through the Grothendieck construction for the corresponding
op-fibration, you will produce exactly the above multipilcation. The similarity
is also visible in the general case if you view $F: C\rightarrow \mathrm{Cat}$
as a category action of $C$, drop the $F$ from the notation and write
$uf$ instead of $F(f)u$ for $f:c\rightarrow c'$ and $u\in F(c)$:
For $c,c',c''\in C$, $x\in F(c)$, $x'\in F(c')$, $x''\in F(c'')$,
$f:c\rightarrow c'$, $u:F(f)x\rightarrow x'$,
$g:c'\rightarrow c''$, $u:F(g)x'\rightarrow x''$ consider the maps
$(f,u):(c,x)\rightarrow (c',x')$ and $(g,v):(c',x')\rightarrow (c'',x'')$
in the Grothendieck construction. If we write composition of maps from
left to right and apply the above mentioned notational simplification, then
the composition of $(f,u)$ and $(g,v)$ can be written as $(fg,(ug)v)$
where $(xf)g$ is the composite
$$xfg \stackrel{ug}{\rightarrow} x'g \stackrel{v}{\rightarrow} x''$$24 F.3d 1037
62 USLW 2799, 9 IER Cases 888
Paul MASCHO, Jr., Appellant,v.Jim GEE; George Franks, sued as Lieutenant George Franks;Arkansas State Highway and TransportationDepartment, Appellees.
No. 93-3515.
United States Court of Appeals,Eighth Circuit.
Submitted March 16, 1994.Decided May 12, 1994.Rehearing Denied June 16, 1994.
John P. Lewis, Hot Springs, AR, argued, for appellant.
Calvin Gibson, Little Rock, AR, argued (Robert L. Wilson and Tom Lorenzo, on the brief), for appellees.
Before BEAM, Circuit Judge, BRIGHT, Senior Circuit Judge, and MORRIS SHEPPARD ARNOLD, Circuit Judge.
MORRIS SHEPPARD ARNOLD, Circuit Judge.
1
Paul William Mascho, Jr., brought this action under 42 U.S.C. Sec. 1983 and Arkansas law against the Arkansas State Highway and Transportation Department ("the Department") and two of its employees following the resolution of Arkansas Employment Security Department proceedings. Mr. Mascho claims that the Department discharged and defamed him in violation of the due process guarantee of the Fourteenth Amendment. The district court1 granted summary judgment in favor of the defendants, and Mr. Mascho appealed. At issue is whether the reasons given for Mr. Mascho's discharge, that he failed to report possible drug use by subordinates, is sufficiently stigmatizing so as to constitute a deprivation of his liberty interest in his reputation. We hold that it is not and therefore affirm. We set forth hereafter such facts as the record would justify a reasonable juror in finding.
I.
2
Mr. Mascho was employed as a geotechnical drill party chief with the Department, responsible for the supervision of a five-person work crew. When performing work at an out of town site, the crew members went home for the weekends while leaving their drilling equipment at the job site. Upon returning to work after one such weekend, the crew discovered approximately $16,000 worth of drilling equipment missing from a Department vehicle. Mr. Mascho reported the theft to the Department and to local law enforcement authorities.
3
Appellee Jim Gee, head of the Department's Material Division, requested an investigation, which was conducted by Appellee First Lieutenant George Franks of the Department Police. During the course of the investigation, information from the United States Drug Enforcement Administration indicated possible drug involvement by members of Mascho's crew. Mr. Mascho was interviewed under oath about his knowledge of any drug use by members of his crew. During the course of the interrogation, Mr. Mascho informed Lieutenant Franks that he believed that he once "smelled the odor of marijuana coming from a motel room where the crew members were staying." Affidavit of Paul Mascho, Jr., at 2-3. After the interview, Mr. Mascho was immediately suspended, and subsequently terminated. The official reason given by Mr. Gee for Mr. Mascho's termination was that he was "not performing the functions of a supervisor."
4
Mr. Mascho filed a claim for unemployment benefits with the Arkansas Employment Security Department ("ESD"). The Highway and Transportation Department challenged this claim, alleging that he was terminated for misconduct. The Department charged that Mr. Mascho violated the spirit of the drug-free workplace policy when he failed to report possible drug use by members of his crew. ESD determined that Mr. Mascho was qualified for benefits, and the Department appealed to an ESD Appeals Referee, who affirmed. Mr. Mascho then instituted the present action.
II.
5
Mr. Mascho claims that the Department wrongfully discharged him and articulated reasons for his discharge which were so damaging to his reputation as to infringe his liberty to secure new employment. Mr. Mascho's complaint alleges that this deprivation of liberty occurred without the due process guaranteed by the Fourteenth Amendment.
A.
6
Mr. Mascho claims that he was wrongfully discharged by the Department. He admits that under Arkansas law, his employment with the Department was terminable at will and that he could be discharged without cause. Nevertheless, he contends that Arkansas law recognizes an exception to the at-will doctrine where an employee was terminated in violation of the general public policy of the state. Public policy of the State of Arkansas was violated, according to Mascho, when he "was terminated for something he did not do."It is "generally recognized that the public policy of a state is to be found in its Constitution and statutes." Kirksey v. City of Fort Smith, 227 Ark. 630, 300 S.W.2d 257, 261 (1957). Other than his conclusory assertion, Mr. Mascho offers no public policy which might have been violated, nor any statute or Constitutional provision which might evidence such a policy. As a result, we conclude that the district court properly granted summary judgment in favor of the defendants on this claim.
B.
7
Mr. Mascho's second claim is that his liberty interest in his reputation was infringed without due process of law, and that he was entitled to notice and a hearing prior to his termination. While termination from state employment does not necessarily amount to a deprivation of a protected liberty interest, the Supreme Court has recognized such an interest where an employee's "good name, reputation, honor, or integrity is at stake because of what the government is doing to him." Board of Regents v. Roth, 408 U.S. 564, 573, 92 S.Ct. 2701, 2707, 33 L.Ed.2d 548 (1972). To establish such a claim, the employee must show defamation by a state official, and that the defamation occurred in the course of the termination of employment. Paul v. Davis, 424 U.S. 693, 710, 96 S.Ct. 1155, 1164, 47 L.Ed.2d 405 (1976). Defamation, for purposes of a due process claim, occurs when a state official "publicly made allegedly untrue charges against [the employee] that would stigmatize [him] so as to seriously damage [his] standing and associations in [his] community, or foreclose [his] freedom to take advantage of other employment opportunities." Shands v. City of Kennett, 993 F.2d 1337, 1347 (8th Cir.1993).
8
Unsatisfactory performance or general misconduct are insufficient to create a stigma that implicates an employee's liberty interest in his reputation. Robinson v. City of Montgomery City, 809 F.2d 1355 (8th Cir.1987); Shands, 993 F.2d at 1347. In Robinson, we held that a city press release was insufficiently stigmatizing to implicate the liberty interests of a discharged police chief where the press release indicated that the city was dissatisfied with the chief's performance. Robinson, 809 F.2d at
|
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] |
Located a 5-minute walk from Tamarindo Beach, Tamarindo Surf Camp Percy offers well-equipped studios and a communal swimming pool. Each 6-day stay includes daily surfing lessons and use of a surfboard and rashguard.
Popular Cities:
San José:
Temperature:
26°C
Good To Know...
Capital:
San José
Languages:
Spanish; Castilian
English
Population:
4,516,220
Area:
51,100 km2
Currency:
₡ (CRC)
Costa Rica, Colón
Related Travel Articles in Costa Rica:
It looks like every beautiful tourist destination in Costa Rica has been overexposed because of the number of tourists that visit this place yearly There are hundreds of things to do which leave the tourists hungry to do so many things within a short time, in their rush to explore the famous places... Read More
The fine coastal island of Costa Rica is greatly defined by its rich and fertile volcanic soil found along its central highlands where most of the world’s finest coffee beans are grown On either side of the highlands lie the tropical lowlands The Caribbean lowlands are swampy, but the Pacific... Read More
Lively and filled with elegant looking Victorian chateaus, Costa Rica's progressive capital city was based on the benefits of the coffee industry The Spanish colonizers named this land Costa Rica (rich coast) because they mistakenly believed there was a lot of gold in here The truth is, its... Read More
I've been to Costa Rica three times, and I usually just go somewhere once, and then never want to go back again It feels like I've checked it off the list, and I'm just over it With Costa Rica, it feels different The entire country is so laid back and happy, and it feels safe My Spanish is pretty... Read MoreHopefully you had a great Sunday – just like we did. Great weather, a nice breeze, delicious food and a good book. Just a perfect sailing day. We escaped the eddy kracken and had the current with us again. Robert read aloud from the book ‘Als Schisser um die Welt’ (‘Around the world as a sissy’) by Jan Kowalsky. Hilarious and entertaining, a fun read, don’t know whether it has been translated into English yet. We love reading aloud to each other out at sea, preferably travel or sailing stories. Great for that are e.g. the books by Tristan Jones, a very Salty Dog.
Besides the Eddy, good things happened within the last days. Since we took a route far from the coast we were able to escape the thunderstorms. Especially along the Florida coast which is sometimes referred to as the lightning capital of the world. Each night we could watch the lightning show at our portside. Only last week a friend of ours cast off from West Palm Beach to deliver a boat to Jacksonville FL, only to return a few hours later – lightning strike! The electronics were gone. We’ve heard more of those stories and are happy to have spared this experience.
Although we slowed down significantly when we had the current against us on Saturday, we’ve been proceeding quite well after that. Only a few hours left till we will reach the Morehead/Beaufort NC inlet. We will let the storm pass by which is building up in the Gulf of Mexico right now. Its predicted route is exactly ours, up the Eastcoast to Hatteras and on to the Azores. It looks like we have to wait until Wednesday and start then, 2.320 nautical miles.
Have a great start into the new week! We’re looking forward to have you on board as we start for the next leg across the Atlantic.Alterations of Tear Film and Ocular Surface in Children with Type 1 Diabetes Mellitus.
To investigate whether diabetes mellitus (DM) affects ocular surface of children with well-controlled type 1 DM. Sixty-five diabetic patients and 55 age-matched controls enrolled to study. Detailed ocular surface assessment including, ocular surface disease index (OSDI) questionnaire, tear film break-up time (TBUT) analysis, Schirmer test, and conjunctival impression cytologic analysis were performed. Schirmer test and TBUT results were significantly lower in DM group than controls (p = 0.001, for all). OSDI scores of all participants were within normal range. Impression cytology analysis showed grade 0 changes in all participants and there was no difference between groups for goblet cell density (p > 0.05). The TBUT results were significantly associated with duration of DM (r = -0.309, p = 0.036). Diabetic children without symptoms, signs, and definite diagnosis of dry eye still had lower TBUT and Schirmer test results than controls; however, impression cytology analysis was similar in both groups.1. Introduction {#sec0005}
===============
Approximately 55 % of primary adrenal tumors are functional \[[@bib0005]\]. Depending on the type of hyperfunction, they can be classified into three major individual tumor types. Tumors with Cushing's syndrome (those secreting glucocorticoids), tumors with primary hyperaldosteronism (those secreting mineralocorticoids), and tumors with an adrenogenital syndrome (those secreting sex steroids) \[[@bib0010]\]. Most commonly, adrenal tumors are discovered fortuitously during abdominal imaging \[[@bib0010]\] as was reported in a series of 7 incidentalomas in Cameroon in 1999 \[[@bib0015]\]. In contrast, we present a series of 7 patients with symptomatic adrenal tumors managed in the Surgery Departments of the Yaounde General Hospital and the Yaounde Gyneco-Obstetric and Pediatric Hospital over a ten-year period from 2009 to 2019. This article complies with the PROCESS guidelines for reporting surgical case series \[[@bib0020]\].
2. Case No 1 {#sec0010}
============
This is a 46-year-old male patient referred for the management of a left adrenal corticoid secreting mass. He presented with a 3 months' duration of painless and progressing abdominal distension, discomfort, insomnia, anorexia, nocturia and rapid weight gain. He took anti-hypertensives and hypoglycemic agents for type 2 diabetes. He was a well-developed, well-nourished male with a blood pressure of 150/90 mmHg, a pulse rate of 86 beats/min, weight 90 kg, waist circumference of 112 cm, and an abdominal girth of 180 cm ([Fig. 1](#fig0005){ref-type="fig"}). He had a lunate fancies, dark stretch marks on the abdomen, hyperpigmentation of the hands, feet, and trunk, and edema of the lower limbs. There was no palpable lumbar mass nor costovertebral tenderness. A CT urogram revealed a left adrenal tumor measuring 23.2 × 31.3 mm strongly enhanced with contrast ([Fig. 2](#fig0010){ref-type="fig"}). Urinary free cortisol was 195 μg/24 h; ACTH \<1 ng / ml; VMA: 10.61 μmol/24 h, blood glucose: 1.9 g/l. He benefited from a left subcostal adrenalectomy ([Fig. 3](#fig0015){ref-type="fig"}) and postoperative corticoid supplementation. He however developed acute adrenal insufficiency due to non-compliance with opotherapy. He was stabilized in the intensive care unit and discharged 6 weeks later in good condition. The histopathology confirmed an adrenal adenoma.Fig. 1Abdominal distension with stretch marks in a 46 year old male patient (case 1).Fig. 1Fig. 2CT urogram showing left adrenal mass (case 1).Fig. 2Fig. 3Left adrenalectomy postoperative specimen (A: en bloc, B: opened, C: under 40 objective lens; Acinar glandular trabecular architecture with giant cells having abundant granular cytoplasm) (case 1).Fig. 3
3. Case No 2 {#sec0015}
============
A 37-year-old woman who presented with complaints of weight gain, galactorrhoea, hypertension for the past year and type 2 diabetes mellitus for 10 years. She was a well-developed, well-nourished with a blood pressure of 150/90 mmHg, pulse rate of 90 beats/min, lunar facies, facio-truncal obesity, abdominal stretch marks, bruises, and edema of the lower extremities. An abdominal CT scan ([Fig. 4](#fig0020){ref-type="fig"}) revealed a left adrenal mass measuring 30 × 19 mm, left renal malrotation with aberrant vascularization. Free urinary cortisol was 250 μg/24 h, ACTH: 43.80 μg/mL, prolactinemia: 116 μg/mL; LH: 6.43 IU/l; FSH: 5.27 IU/l; blood glucose: 1.20 g/l.Fig. 4Abdominal CT urogram showing left renal malroatation and left adrenal mass (case 2).Fig. 4
A left subcostal adrenalectomy ([Fig. 5](#fig0025){ref-type="fig"}) was performed, and corticosteroid supplementation was initiated. Acute adrenal insufficiency developed after she arrested corticotherapy but this was rapidly corrected. The pathology report confirmed an adrenal adenoma.Fig. 5Left subcostal incision (case 2).Fig. 5
4. Case No 3 {#sec0020}
============
A 17-year-old girl who had menarche at 12 years and menstruated for a duration of 6 months. This was followed by amenorrhoea and an unusual virilization marked by the appearance of a
|
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the dead weight and dimensions of the product itself
We Only supply Australian stock with a Genuine Australian Manufacturers Warranty.
All stock supplied by Bubs n Grubs is sourced through genuine Australian Suppliers. This means when you purchase from Bubs n Grubs, you will get a genuine Australian manufacturers warranty and all of our products comply with Australian Safety Standards. Prams and other items purchased from non Australian Distributors wont be modified and tested to meet the Australian Safety Standards. You wont have this issue when you Purchase from Bubs n Grubs!
Should your purchase prove faulty within the warranty period you can return your product to us and we will forward your repair to the genuine supplier repair department at no charge to you and you are protected by the Australian Consumer Law. Bubs n Grubs is wholly Australian owned and operated and also believes in only supporting Australian companies.
Grey Market Importers Online – Beware!
Grey Market Importers do not purchase their products from Australian suppliers. This means that should your item prove faulty within the warranty period you may need to return the product to an overseas address (which can take months) or your item may be repaired by someone who has not been certified to perform such work. Worse – it may not meet the Australian Safety standards as we have seen several overseas “no name brands” and “baby store brands” recently in this situation.
This product is backed by a Full Manufacturers Return to Base Warranty.
Standard Terms and conditions apply in line with the Australian Consumer Laws.
We will do our best to give you the best service reasonably possible if you have any problem with your purchase.
Most items are dispatched within 24 hours of payment being received (DIRECT DEPOSIT may take longer).
Furniture Items can from time to time take up to 12 weeks to deliver if both the manufacturer runs out of stock as well as our own warehouses. This is rare. If you wish to confirm availability – do not hesitate to contact us.
Once items are dispatched, regular Australia Post or courier delivery times apply and an email with the online tracking info is sent to you.
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Have a peaceful night's sleep under the Cloud B Twilight Sea Turtle's starry night sky. This enjoyable and educational nightlight is made to assist children fall asleep a lot easier as well as provide consciousness to endangered sea animals.
(Some of the proceeds from the product is going to be given in an international conservation organisation)
Twilight Sea Turtle's beautiful shell illuminates in 3 soothing colours as well as illuminating five endangered sea friends... the Blue Whale, California Sea Otter, Knsna Seahourse, Leatherback Turtle and Vaquita Dolphin.
Mamas & Papas Gingerbread Musical Mobile - Relax, entertain and keep baby amused with fun characters that face downwards towards baby and gently rotate when the soothing melody plays. Features: Easily attaches onto the side of a cot or wall, Three hanging bars to attract baby's gaze, Characters face down slightly so that they can be seen from baby's viewpoint, Music box plays 'Rock a Bye Baby', High quality rigid frame.
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Choose the ZipMoney Payment method in your checkout to Pay for your orders over time and enjoy Flexible Interest Free Monthly Payments! Real Time Credit Decisions. It's Fast and Easy.A MAN IN his 40s has been killed in a shooting incident in Coolock, North Dublin this afternoon.
The incident occurred in the front garden of a house in the Killbarron Avenue area of Coolock at around 3.30pm this afternoon.
Gardaí believe three men wearing balaclavas were involved in this incident and left the scene in a silver Toyota Avensis with a registration 04-D-71806.
The car was found abandoned and on fire in the Castletymon Gardens area of Coolock at approximately 3:45pm. The scene remains preserved for a Garda technical examination.
It is understood the shooting took place near the home of another shooting victim, Sean Little, whose body was found near a burnt out car on the M1 motorway last week.
Gardaí have not yet said whether the incidents are related.
The body remains at the scene of the shooting pending examination by the Garda Technical Bureau and the Office of the State Pathologist has been notified.
An incident room has been established at Ballymun Garda Station.
Gardaí are appealing for anyone with information to contact them at Ballymun Garda station on 01 666 4400, the Garda Confidential Line on 1800 666 111, or any garda station.
Gardaí said they are particularly interested in speaking to anyone who was in the vicinity of the Kilbarron Avenue or Castletymon Gardens areas of Coolock between 3:15pm and 4pm.
With reporting from Garreth MacNamee.Search
Copyright
Become a Fan
Good news, you're thinking. Your company's just been sued for sex discrimination, but your lawyer tells you that her discrimination claim stinks. You're almost certainly going to beat it. W00t!Squee!
Not so fast with your w00ts and your squees. As employment lawyers, we see this scenario
play out far too often. Company gets hit with a weak discrimination claim. Turns out something bad happened to the plaintiff after he or she complained about the bogus discrimination. Wa-bamm! Now the company's stuck defending a much stronger retaliatory-discrimination claim.
This happened the other day here in Boston. The state's Probation Department faced a sex-discrimination claim (among other things) from an assistant chief probation officer. The case went all the way to a jury trial, which is unusual (less then one percent of these cases try). The Suffolk County jury found in the Department's favor on the sex-discrimination claims, but ruled for the plaintiff in her retaliation claim. It awarded her $6,000 in compensatory damages, and … wait for it … half a million dollars in punitive damages. Plus, now she's entitled to her attorneys' fees.
Now to be fair, the Probation Department has been having a bad year as the subject of daily newspaper stories about corruption and patronage. (For The Boston Globe's extensive coverage, click here.) But the lesson is still an apt one. In this case, after the employee complained of sex discrimination, she was stripped of supervisory duties and reassigned to cover the front desk. In its defense, the Department said that her performance had declined. Maybe it had. But that's a weak defense in a retaliation claim. (For more coverage of the case, see Marcella Bombadieri's piece in the Globe.)
Employers: When you're facing a potential discrimination lawsuit, you have to be extra careful to avoid doing something that could end up giving the employee a much stronger retaliation claim. It's a delicate situation to be in, but the wrong actions by the employer can be just the thing that the plaintiff needs to end up with a windfall.
For tips on how to treat a complaining employee, tweet or direct-message me at @jayshep, or send me an
A recent study by Shepherd Law Group shows that noncompete litigation nationwide has continued to trend upward, despite a slowing economy and legislative attempts to curb noncompetes. The latest study shows that noncompete litigation has more than doubled since 1995, and has increased by 61 percent from 2004 to 2009.
Tracking noncompete litigation across the United States is difficult. Unlike in discrimination cases, there are no government agencies to track noncompete litigation. What is more, the various state and federal courts have no mechanism for keeping track of noncompete cases. To get around these problems, the Shepherd Law Group study analyzes judicial opinions published by state and federal courts around the country. This data gives some indication of trends in noncompete litigation over time.
To be sure, the data has limitations. First, since it's based solely on published court opinions, it substantially underreports the number of noncompete lawsuits filed. Many if not most noncompete cases never result in a judge's written decision, and trial-court decisions in many states don't always get picked up by LexisNexis, where this data was collected. Moreover, the number of cases for a given year changes over time, for reasons known only to Lexis. (Compare the data in this post with 2009's "Eight ways to lose a noncompete case" and 2007's "Are noncompetes the new Sarbanes-Oxley?.") The likely explanation is that there is a lag between the filing and the publishing of court decisions.
So while the actual number of published decisions in a given year may not be that useful, the trends are. And if you're wondering about this year, the data suggests that the trend continues. If you prorate the first eleven months of 2010 over the course of a full year (that is, multiply by twelve elevenths), you get an estimate of 965 cases, which is a five percent drop from 2009. But that number
|
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time in the future.
Until eventually, the visions began to grow weaker and rarer. The Daughters no longer were able to summon up knowledge of what was to come at will. Having no use for Sightless seers, monarchs cast aside their Daughters, forcing them to live amongst the commonfolk, who had long feared their powers. Fearing for the lives of their own daughters, the Daughters slowly began to send their children down different paths. Many became wizards, for the power of magic was strong in their veins. But within only a few hundred years, the descendants of the Daughters, now Daughters themselves, no longer had visions, or remembered the Library.
War came again, and it brought disasters with it. Earthquakes ravaged the lands as much as did armies, and tunnels collapsed. Without Daughters to clear the rubble, countless centuries of priceless knowledge were sealed off from the world, locked in airtight chambers. Slowly, most of Kesthor collapsed upon itself.
Eventually, those portions of it which remained accessible became simply more ruins to be plundered and adventured in. The Daughters disappeared, and the most priceless of Kesthor’s treasures were lost.
Until, only a few centuries ago, the Daughters returned. But now, they were different. A sinister coven of witches and sorceresses, the Daughters now spread death and chaos throughout the land. It often seems that they work to no specific ends, but for an organization as secretive and powerful as the Daughters, this most likely means that they simply keep their secrets far too well.
Across the land, those few scholars who know the ancient tales of the Daughters wonder of this change. And yet, wondering does nothing to stop the damage dealt by these insane magi. For that, adventurers are needed.
The Why
Fairly recently, a band of adventurers, seeking forbidden knowledge, launched an expedition into a portion of the Library. Although they did not find what they sought, they did locate a ritual for a summoning. Hoping that the summoned creature would be able to answer their thirst for dark knowledge, they conjured it, lost control, and were slain. Since then, the demon has wandered the halls and rooms of the library, using its innate powers to make passages where there are none. It has learned of the Daughters, and their connection to the Library, and it has found in them something to amuse itself.
The Demon began to write, penning tomes of darkness and writing them in blood. When placed upon the shelves, this new work gradually worked its way into the minds of the descendants of the Daughters. Since then, the Demon has penned countless librams and manuals, which plague those with the proper blood with horrific nightmares and visions, gradually driving them insane. By carefully selecting what to write, the Demon is then able to control the poor seers, driving them to commit deeds they would not previously have done. Now, they are at his command, as are their daughters, for it is within their very blood to see the Library.
The Library
The Library now lies in ruins, its many wings, chambers, and halls cut off from each other by cave-ins and monsters which have since moved into the wrecked rooms. The books remain in surprisingly good condition, for many efforts were made to preserve them. The lavish decorations once spread across the library now lie in tatters, for the gold and silver in them proved too tempting to treasure-hunters. Yet, where these treasures were inaccessible, glorious statues and tapestries hang, relics of an ancient past.
The Demon has successfully cleared many tunnels, although he occasionally seals them back up after himself. He no longer can be easily reached from the surface, for he has ventured deep into the Atheneum, planting traps and cave-ins to discourage those who might happen upon him. The intelligent beings which have made homes within the ruins fear him, frequently migrating, just to stay out of his way. Occasionally, he brings a Daughter down to the Library to serve him, but this is rare - he far prefers to work his havok from afar.
Of course, the real treasure here is the books. The collection of knowledge spread throughout the caves is essentially priceless, if one can find the book he needs.
Adventure Hooks
1. A giant, underground ruin full of treasure and monsters is just begging for adventurers to come clean it out. Since almost nobody knows of the true size of the Library, however, it may take awhile for the PCs to realize all the ruins they’ve been excavating are part of the same complex.
2. The Daughters are now basically an evil cult, perfect for use as a nemesis. Since the women are actually good people driven insane, however, the PCs may hope for a way to stop them without killing them all. Of course, a quest to hunt down the demon controlling them could be just what the doctor ordered.
3. The PCs could need some specific bit of knowledge, which now lurks only within the dark halls of the Atheneum. While they’re there, they’d best watch out for the Demon.
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Ooo... I have a penchant for insane cults, and I like the way their precognition works. Honestly, I really can't think of anything to add to this. (Note to self, may have at last found a use for The World's Largest Dungeon...)
Regions
Freetext
The PCs come across a wild thicket of luscious looking blackberries. They eat the berries and become drunken fools. Later they find out that the berries were part of a fae garden and were intended for fae wine. In payment for stealing the berries, the mischievious fae make life inconvenient for the PCs. Horses are untied, water skins are drained, spare clothing is drug into the water, etc.Class Ring Returned After 50 Years
This is an archived article and the information in the article may be outdated. Please look at the time stamp on the story to see when it was last updated.
Please enable Javascript to watch this video
Our story today begins where it ended, at Red Bud High School. 59 years ago Orville Dumstorff was a teenager in this tiny gym.
"He was very quiet," remembers Joan Rahn. "He was only here his junior and senior year and he was very quiet."
"Very quiet," agrees Ruth Menard. "Very quiet. He was not a clown or anything he was a nice man."
He wore a class ring, graduated and joined the Marines. While stationed in California, Dumstorff decided to see the Palomar Mountain Observatory.
"We got up there and it was snowing so they closed the doors and we never got to see the telescope," says Orville Dumstorff.
But things snowballed into a, well, snowball fight. In the cold chaos the class ring slipped off his finger, lost forever, until three weeks ago when his brother called.
"I was kind of thinking what could happen to my class ring," says Dumstorff. "I ain't got no class ring."
An Oregon woman bought the band at an estate sale, saw the initials and called the high school where today, it was returned to its rightful owner.
"Nose started running eyes started to tear up, fantastic," says Dumstorff. "Well monetary value its not that much but the people behind it. That made it remarkable. Kind of makes you want to hug everybody."
And he did, like Larry and Madonna Hill.
"They kept us in hiding cause they didn't want Orville to see us," says Hill.
Orville introduced the two to each other, 48 years ago.
"I just feel kind of humble with all the people who showed up for me, I didn't do anything great," says Dumstorff.
"Not only was today the first time that Orville had stepped foot in Red Bud high school in more than 50 years," says Patrick Clark. "But his class was the first class to graduate from this building."
Today they saw their friend for the first time in a long time and everything old was new again.
"It's just exactly like it was when we were here," says Joan Rahn.
"Well it was exactly like I imagined," says Dumstorff. "But it was a lot better shape than I thought."
There was a lot of fellowship among friends and family, all because of one band.
"All the things that I thought would never happen for 50 years happened today," says Dumstorff.
"How do you top this?" asks Clark.
"Go to Heaven," says Dumstorff.
So our story has come full circle, just like the ring that was returned to Red Bud.Ontario Highway 50
King's Highway 50, commonly referred to as Highway 50, was a provincially maintained highway in the Canadian province of Ontario. The highway, which was decommissioned in 1998, is still referred to as Highway 50, though it
|
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and bags from the sea and sent them to Philadelphia for adjudication.
During October she was attached to the 2nd Division North Atlantic Blockading Squadron and on 21 October captured CSS Wando attempting to run through with a cargo of cotton.
During December Fort Jackson fought in the battle off Wilmington and in the first bombardment of Fort Fisher (24–25 December) during which she covered troop landings and received on board the dead and wounded.Q:
Google Maps API v3 navigation (like Google maps for android)
In our app we do use the Google Maps API a lot. The app (web) is build in Jquery, CSS, HTML.
The app runs in the browser.
But we like to add the navigation functions like the Android Google Maps native in our webapp.
Is that possible with the Google Maps API or do we need to convert to native to realise
something like that?
A:
I just wrote a long winded answer introducing the Directions service, luckily I re-read the question before answering...
No there is no Javascript equivalent of the android navigation services unless I'm very much mistaken. I imagine it would be possible to create a custom solution (I presume you want the route to update as you travel based on your gps coords etc) leveraging the route-parts returned from a directions request but this would be none trivial.
I would have thought the simplest solution would be to pass the start and end points of your route to the native maps app, however I am no expert at Android development (or interaction between a web app and a phone).
A Geeky Treasure Hunt
Today, Cheri and I went on our first Geocaching excursion. For those who don’t know, Geocaching is like a world-wide treasure hunt. People will place caches in different locations, record the location’s coordinates, and publish the coordinates on a geocaching website (such as www.geocaching.com) Then people who visit the website can enter their location to get the coordinates of caches close to them. Then you can use your GPS device to locate the cache. Most caches have a logbook and some kind of treasure. The logbook contains notes from everyone who has visited that cache. The treasure can be any range of small trinkets. The main rule of caches is that if you take something, make sure you leave something. That way the cache always has something in it other than the logbook.
The cache we found today was in a wooded area near a park not to far from our apartment. I got the coordinates from Geocaching.com, and placed them in my new Garmin eTrex GPS device my parents got me for Christmas. Then it told me where to go to find it. It was really fun trying to figure out where it was. We eventually found it in a hollowed out tree trunk. It was a camouflage ammunition box. This particular cache was a book-crossing cache. In this cache people take and leave books to pass around. So the cache had about four books in there, plus the logbook. We didn’t take any of the books, because we didn’t bring any to leave, but we still signed the logbook. After that, we placed the cache back where we found it for the next visitors.
This was a very fun activity and Cheri and I look forward to doing it again. There are plenty of items hidden around the area we live, so we don’t even have to go far to find treasure! I feel like a 21st century pirate!
FYI
My name is Eric and I live in Burke, Virginia.
Here are a few tidbits about me: Chesapeake, Virginia is my hometown; Cheri is my lovely wife; Photography and pool are my most active hobbies; Crohn's Disease is my ailment; Virginia Tech and The George Washington University are the schools I graduated from; Cookies & Cream is my favorite ice cream flavor.
Also, fallenposters is the alias I use on most websites. It was the first username I came up with when joining instant messenger in college. The first thing I saw was the posters that had fallen from my dorm room wall, and the rest is history."Fifty years ago women were considered outrageous if they appeared in the media in a bikini and only men presented motoring shows. Now a woman in the media is considered lucky if it's only her cleavage - not her labia - on display and... erm... it's still only men who get to present motoring shows. TV, radio and UK comedy circuit regular Kate Smurthwaite will talk about the state of the media and her own experiences and call for immediate radical action. Bring battering rams and grappling hooks! The revolution starts here and we will televise it ourselves."
Kate Smurthwaite is a well known feminist activist and campaigner. She is the vice-chair of Abortion Rights UK, an active member of London Feminist Network and the Secular Society and a regular contributor to The F Word Blog. Kate is also a highly regarded British comedienne, having performed more than 2,000 shows including the Bloomsbury Theatre, Soho Comedy Club, Comedy Cafe, Edinburgh Festival, and the New York and Malmo Comedy Festivals. She is currently resident compere at the Soho Comedy Club and the host and writer of London’s most popular live political panel show The Comedy Manifesto. She is also a seasoned broadcaster, contributing to television and radio programmes including BBC Television and BBC Radio 4 and 5 and has hosted shows on a range of UK independent radio stations.
Monday, September 26, 2011
[trigger warning] I was born in London and I'm not one for pointless displays of patriotism, but I like London, I like living here and being from here. I was pretty horrified by this video from the BBC though. It's about an exhibition of tattoo art going on. Fair enough. But look at the guy 1m10 in... He describes his London-theme tattoo as featuring "Sherlock Holmes, dead prostitutes and Big Ben". Holy fuck. When did "dead prostitutes" become an ok thing to casually have tattooed on your arm under the heading "London theme"? And the interviewer doesn't stop him or question him. He allows him to carry on talking and describe himself as "an English gentleman". Lets remember lads, all together: real gentlemen don't trivialise the murder of prostituted women. Did that really need saying?
Wednesday, September 21, 2011
Hello all. Sorry for the round-robin message, I know it's only a small number of you who are letting the others down but I really think I need to have a word here.
It's about social media. Yes Twitter, Facebook and blogs are exciting new platforms for communication and sharing of information. We can certainly look at them and see what subjects people are discussing. However what we can't do is this: Take one or two specific quotes from members of the public on Twitter, Facebook or a blog and act like that's the nation's opinion.
"Last night, several messages were posted under Ramsay’s blog by readers mocking his background. One of them pretended to be his mother, writing: ‘Adam darling, We’ve got no caviar left and the staff have taken the day orf... please be a dear and pick some beluga up when you and your Uni chums pop into Fortnums... Mwah, mwah, Mumsy.’"
Stop press! SEVERAL messages? Really so lets say "at least three". Clearly what Ramsay was doing (he was alleged to have been something to do with UK Uncut) was attracting a lot of attention. Lets assume 20,000 people heard of him and his blog. And lets assume five of them wrote something "mocking his background" (I did have a look at the time, that's about right). That would be one in 4,000 people. I'm pretty sure that one in 4,000 people in this country has written to Points of View because they're "morally outraged" by Blue Peter. And at least two in 4,000 go to the pub and try to convince their friends that Elvis is alive and works in Lidl. It's not a measure of national opinion, it's a measure of the random opinions of a tiny handful of people. It hugely smacks of "I've run out of arguments to support my stupid point" and also rather of "I know I'll get my teenage nephew to write something on Twitter and then quote him in the national press".
"The ploy sparked a wave of fury on Twitter, with one user saying: 'A country full of problems and in desperate need of solutions, and the Lib Dems are voting on banning Page 3. Sheesh!'"
They have exactly one example of this "wave of fury" and it's not even from someone who says they disagree with the measure - its from someone who thinks it shouldn't be a priority. And where is this "wave" really? Twitter uses hashtags (where you write the theme of a comment in the form #Page3 so people can search for it) to allow you to see who else out of their 100 million global users is talking about a particular subject. At noon today I was interviewed on the subject by Wendy Austin from BBC Ulster. She put a post up on Twitter asking people to contact her show with their opinions. That was 14 hours ago and there have been 10 comments about #Page3 since - none of them really expressing "fury". So that's less than one
|
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] |
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The effective home remedies for baldness and hair loss in men include oil massages and including coconut milk, eggs, avocados, orange juice, aloe vera, neem paste, henna, mayonnaise, honey, black pepper, vinegar, and lemon juice in their diet. The remedies also include cutting back on red meat, eating nuts and brown rice, boosting B-complex vitamin intake, and maintaining good thyroid health.
For millions of men across the world, regardless of culture, class, nationality, religion, or color, hair loss is an unavoidable aspect of growing older. Fortunate are those who do not face hair loss problems even in their old age. However, a majority of men face this issue in their 40s, 50s, or even earlier.
Causes of Baldness or Hair Loss in Men.
There are a number of causes of male hair loss, including:
Male pattern baldness Alopecia Fungal infections Psychological disorders Chemotherapy side effects Nutrient deficiencies Hormonal imbalances Lack of circulation on the scalp Stress.
It is important to note that hair loss occurs in women as well, for some similar reasons, and some different ones. We will cover hair loss in women in a separate article. Men predominantly suffer from this health condition, particularly male pattern baldness and early onset hair loss from age 20-40.
However, there are ways to slow down the rate of male hair loss or baldness, and even stimulating the hair follicles to reproduce hair. A few home remedies for hair loss and baldness issue are discussed below.Q:
Trouble with Link List insert placement function in C.
So here's the deal. I am probably way out of my competency on this (pretty new to C and programming in general). I'm getting segfault errors and the fn is not really doing what I need (as indicated by comments). I really appreciate any insight here. Gonna go read a bunch, was more or less following steps to get to this point, so I apologize for this, but I figure I get a line out there while I read up.
The idea is if input was:
1
2
3
4
Output should be:
1
1 2
1 2 3
1 2 3 4
Thanks in advance!
#include "orderedList.h"
Node *orderedInsert (Node * p, int newval)
/* Allocates a new Node with data value newval
and inserts into the ordered list with
first node pointer p in such a way that the
data values in the modified list are in
nondecreasing order as the list is traversed.
*/
{
if(p == NULL)
{
p = malloc(sizeof(Node));
p->data = newval;
p->next = NULL;
return p;
}
Node * tmp = malloc(sizeof(Node));
tmp->data = newval;
while(p!= NULL && p->data < tmp->data)
{
p = p->next;
}
p->data = tmp->data;
p->next = NULL;
return p;
}
void printList (Node * p)
/* Prints the data values in the list with
first node pointer p from first to last,
with a space between successive values.
Prints a newline at the end of the list.
*/
{
while (p!= NULL)
{
printf("%d \n", p->data);
p = p->next;
}
}
A:
It's a bit tricky. You could use a Node** (a pointer to a pointer to a Node) to keep track of the correct insert position.
This code should work:
Node *orderedInsert (Node * p, int newval)
/* Allocates a new Node with data value newval
and inserts into the ordered list with
first node pointer p in such a way that the
data values in the modified list are in
nondecreasing order as the list is traversed.
*/
{
Node * tmp = malloc(sizeof(Node)); // will need a new node anyway, so put it first
if(tmp == NULL)
return 0; // no memory error
tmp->data = newval;
if(p == NULL || newval < p->data) // this will also handle the case
{ // when the new node is the first
tmp->next = p;
return tmp;
}
Node** pp = &p->next; // the pointer to pointer
// where the new node is inserted
while((*pp)!= NULL && (*pp)->data < tmp->data)
{
pp = &(*pp)->next;
}
tmp->next = *pp; // *pp is the rest of the list that comes after new node
*pp = tmp; // now insert the new node
return p; // return the beginning of the list
}
4-Star Rarity (Legendary)
Heroes, X-Men
4-Star Rarity (Legendary)Heroes, X-Men
Level 2: No Change
Level 3: Create a 1 -turn Purple Repeater tile...
-turn Purple Repeater tile... Level 4: No Change
Level 5: No Change
Level 2:...create 2 strength 72 Purple Strike tiles.
Purple Strike tiles. Level 3: No Change
Level 4:...create 3 strength 76 Purple Strike tiles.
strength Purple Strike tiles. Level 5:...create 3 strength 126 Purple Strike tiles.
Level 2: Deal 2933 damage...
damage... Level 3:...remove up to 2 enemy Strike, Attack, Protect, or Countdown tile s.
enemy Strike, Attack, Protect, or Countdown tile. Level 4: Deal 5161 damage...
damage... Level 5: Deal 9448 damage...
Level 2:...improve it by 97.
. Level 3:...create 1 strength 135 Protect tile...
Protect tile... Level 4:...fortify 2 friendly Strike, Protect, or Attack tile s and improve them...
friendly Strike, Protect, or Attack tile and improve... Level 5:...create 2 strength 135 Protect tile s...improve them by 128.
Recruit Magik! S.H.I.E.L.D. Training - Heroes for Hire
Starts: 2/14/19, 7:00am ET
Ends: 2/21/19, 7:00am ET
Price 7,000 Hero Points
Contents:
Rocket & Groot (Awesome Mix Volume 2) Blue Cover
Iron Fist (Danny Rand) Blue Cover
16x Elite Tokens
6x Command Points
20,000 Iso-8 Magik & Friends - Limited Vault
Starts: 2/14/19, 7:00am ET
Ends: 2/19/19, 2:00am ET
80 Items:
1x Legendary Token
3x Beginner Support Tokens
1x Random Magik (Classic) Cover
2x Random 4-Stars from the Call for Backup missions, with an option of the following characters:
Bishop (Classic)
Rocket & Groot (Awesome Mix Volume 2)
Iron Fist (Danny Rand)
21x 3-Star Covers
3x Featured
18x Random
52x 2-Star Covers
10x Featured
42x Random Event Schedule Strange Sights - Story Event
Starts: 2/14/19, 7:00am ET
Ends: 2/18/19, 2:00am ET
Magik (Classic) in Placement Reward S.H.I.E.L.D. Training - Character Release Event
Starts: 2/14/19, 7:00am ET
Ends: 2/21/19, 7:00am ET
Rewards tokens to Strange Sights, random cover of Magik, and more! The Hunt - Story Event
Starts: 2/17/19, 7:00am ET
Ends: 2/22/19, 2:00am ET
Magik (Classic) in Progression Reward
Rewards tokens to the Magik & Friends Vault Disappearing Act - Versus Tournament
Starts: 2/17/19, 8:00am ET
Ends: 2/20/19, 3:00pm ET
Magik (Classic
|
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] |
surface is poor in topsoil, with the result that the forest “really grows on the soil and not from the soil”.[59] When the forest is eliminated, it is not replaced, because all that is left is a terrain with few nutrients that then turns into a dry land or one poor in vegetation. This is quite serious, since the interior of the Amazonian forest contains countless resources that could prove essential for curing diseases. Its fish, fruit and other abundant gifts provide rich nutrition for humanity. Furthermore, in an ecosystem like that of the Amazon region, each part is essential for the preservation of the whole. The lowlands and marine vegetation also need to be fertilized by the alluvium of the Amazon. The cry of the Amazon region reaches everyone because “the conquest and exploitation of resources… has today reached the point of threatening the environment’s hospitable aspect: the environment as ‘resource’ risks threatening the environment as ‘home’”.[60] The interest of a few powerful industries should not be considered more important than the good of the Amazon region and of humanity as a whole.
49. It is not enough to be concerned about preserving the most visible species in danger of extinction. There is a crucial need to realize that “the good functioning of ecosystems also requires fungi, algae, worms, insects, reptiles and an innumerable variety of microorganisms. Some less numerous species, although generally unseen, nonetheless play a critical role in maintaining the equilibrium of a particular place.”[61] This is easily overlooked when evaluating the environmental impact of economic projects of extraction, energy, timber and other industries that destroy and pollute. So too, the water that abounds in the Amazon region is an essential good for human survival, yet the sources of pollution are increasing.[62]
50. Indeed, in addition to the economic interests of local business persons and politicians, there also exist “huge global economic interests”.[63] The answer is not to be found, then, in “internationalizing” the Amazon region,[64] but rather in a greater sense of responsibility on the part of national governments. In this regard, “we cannot fail to praise the commitment of international agencies and civil society organizations which draw public attention to these issues and offer critical cooperation, employing legitimate means of pressure, to ensure that each government carries out its proper and inalienable responsibility to preserve its country’s environment and natural resources, without capitulating to spurious local or international interests”.[65]
51. To protect the Amazon region, it is good to combine ancestral wisdom with contemporary technical knowledge, always working for a sustainable management of the land while also preserving the lifestyle and value systems of those who live there.[66] They, particularly the original peoples, have a right to receive – in addition to basic education – thorough and straightforward information about projects, their extent and their consequences and risks, in order to be able to relate that information to their own interests and their own knowledge of the place, and thus to give or withhold their consent, or to propose alternatives.[67]
52. The powerful are never satisfied with the profits they make, and the resources of economic power greatly increase as a result of scientific and technological advances. For this reason, all of us should insist on the urgent need to establish “a legal framework which can set clear boundaries and ensure the protection of ecosystems… otherwise, the new power structures based on the techno-economic paradigm may overwhelm not only our politics, but also freedom and justice”.[68] If God calls us to listen both to the cry of the poor and that of the earth,[69] then for us, “the cry of the Amazon region to the Creator is similar to the cry of God’s people in Egypt (cf. Ex 3:7). It is a cry of slavery and abandonment pleading for freedom”.[70]
The prophecy of contemplation
53. Frequently we let our consciences be deadened, since “distractions constantly dull our realization of just how limited and finite our world really is”.[71] From a superficial standpoint, we might well think that “things do not look that serious, and the planet could continue as it is for some time. Such evasiveness serves as a license to carrying on with our present lifestyles and models of production and consumption. This is the way human beings contrive to feed their self-destructive vices: trying not to see them, trying not to acknowledge them, delaying the important decisions and pretending that nothing will happen”.[72]
54. In addition, I would also observe that each distinct species has a value in itself, yet “each year sees the disappearance of thousands of plant and animal species which we will never know, which our children will never see, because they have been lost forever. The great majority become extinct for reasons related to human activity. Because of us, thousands of species will no longer give glory to God by their very existence, nor convey their message to us. We have no such right”.[73]
55. From the original peoples, we can learn to contemplate the Amazon region and not simply analyze it, and thus appreciate this precious mystery that transcends us. We can love it, not simply use it, with the result that love can awaken a deep and sincere interest. Even more, we can feel intimately a part of it and not only defend it; then the Amazon region will once more become like a mother to us. For “we do not look at the world from without but from within, conscious of the bonds with which the Father has linked us to all beings”.[74]
56. Let us awaken our God-given aesthetic and contemplative sense that so often we let languish. Let us remember that “if someone has not learned to stop and admire something beautiful, we should not be surprised if he or she treats everything as an object to be used and abused without scruple”.[75] On the other hand, if we enter into communion with the forest, our voices will easily blend with its own and become a prayer: “as we rest in the shade of an ancient eucalyptus, our prayer for light joins in the song of the eternal foliage”.[76] This interior conversion will enable us to weep for the Amazon region and to join in its cry to the Lord.
57. Jesus said: “Are not five sparrows sold for two pennies? Yet not one of them is forgotten in God’s sight” (Lk 12:6). God our Father, who created each being in the universe with infinite love, calls us to be his means for hearing the cry of the Amazon region. If we respond to this heartrending plea, it will become clear that the creatures of the Amazon region are not forgotten by our heavenly Father. For Christians, Jesus himself cries out to us from their midst, “because the risen One is mysteriously holding them to himself and directing them towards fullness as their end. The very flowers of the field and the birds which his human eyes contemplated and admired are now imbued with his radiant presence”.[77] For all these reasons, we believers encounter in the Amazon region a theological locus, a space where God himself reveals himself and summons his sons and daughters.
Ecological education and habits
58. In this regard, we can take one step further and note that an integral ecology cannot be content simply with fine-tuning technical questions or political, juridical and social decisions. The best ecology always has an educational dimension that can encourage the development of new habits in individuals and groups. Sadly, many of those living in the Amazon region have acquired habits typical of the larger cities, where consumerism and the culture of waste are already deeply rooted. A sound and sustainable ecology, one capable of bringing about change, will not develop unless people are changed, unless they are encouraged to opt for another style of life, one less greedy and more serene, more respectful and less anxious, more fraternal.
59. Indeed, “the emptier a person’s heart is, the more he or she needs things to buy, own and consume. It becomes almost impossible to accept the limits imposed by reality… Our concern cannot be limited merely to the threat of extreme weather events, but must also extend to the catastrophic consequences of social unrest. Obsession with a consumerist lifestyle, above all when few people are capable of maintaining it, can only lead to violence and mutual destruction”.[78]
60. The Church, with her broad spiritual experience, her renewed appreciation of the value of creation, her concern for justice, her option for the poor, her educational tradition and her history of becoming incarnate in so many different cultures throughout the world, also desires to contribute to the protection and growth of the Amazon region.
This leads to the next dream, which I would like to share more directly with the Catholic pastors and faithful.
CHAPTER 4
AN ECCLESIAL DREAM
61. The Church is called to journey alongside the people of the Amazon region. In Latin America, this journey found privileged expression at the Bishops’ Conference in Medellin (1968) and its application to the Amazon region at Santarem (1972),[79] followed by Puebla (1979), Santo Domingo (1992) and Aparecida (2007). The journey continues, and missionary efforts, if they are to develop a Church with an Amazonian face, need to grow in a culture of encounter towards “a multifaceted harmony”.[80] But for this incarnation of the Church and the Gospel to be possible, the great missionary proclamation must continue to resound.
The message that needs to be heard in the Amazon region
62. Recognizing the many problems and needs that cry out from the heart of the Amazon region, we can respond beginning with organizations, technical resources, opportunities for discussion and
|
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4558
] |
p* value was performed to validate differences in label intensity between inner and outer capsular layers (a), and between inner capsular layer and control tenon's (b) with significantly lower expression in the inner capsular layer (c), αSMA and TGFβ are reported as manual cell counts with significantly higher positivity in the excised capsules (d).
We also observed increased cellular expression of αSMA (p = 0.02) and TGFβ (p = 0.008) in the fibroblasts within the capsules compared to the controls ([Table 3](#pone.0187506.t003){ref-type="table"}). The distribution of the marker positive cells was not layer specific and not limited to either inner or outer layers of the capsule ([Fig 2](#pone.0187506.g002){ref-type="fig"}).
{#pone.0187506.g002}
Discussion {#sec008}
==========
Fibrosis of the capsule surrounding a glaucoma implant remains the main cause of suboptimal pressure control and failure of drainage procedures \[[@pone.0187506.ref033]\]. In this study, we examined fibrous capsules surrounding failed Ahmed implant for expression of a number of extracellular matrix proteins and cellular markers. We demonstrated a consistent trend of altered expression of molecules that suggest profibrotic activity as indicated by increased expression αSMA and TGFβ, together with decreased expression of ECM proteoglycan/GAGs such as decorin, lumican and chondroitin sulfate as well as fibrillar collagen III. It was surprising to note altered expression of several molecules in the excised capsule several months/years following shunt implantation.
Histologic findings in the capsular tissue were similar to previous reports which described an outer more vascular layer with loosely arranged matrix and an inner relatively avascular layer with dense connective tissue \[[@pone.0187506.ref006], [@pone.0187506.ref034]\]. The outer layer however was similar to control tenon's in terms of histopathological characteristics as well as expression trend for most of ECM molecules used in this study. Tenon's capsule is a vascular connective tissue that drapes the shunt plate, absorbs and drains aqueous in the initial period after surgery \[[@pone.0187506.ref006], [@pone.0187506.ref035]\]. It is believed that tenon's tissue fibroblasts contribute largely to the encapsulation and several studies have utilized tenon's tissue fibroblasts to understand bleb failure after glaucoma surgery \[[@pone.0187506.ref036]--[@pone.0187506.ref040]\]. Therefore as a baseline tenon's control helps to provide the evidence to speculate several potentially important interactions.
Increased expression of αSMA, an indicator of activated myofibroblasts which are key effector cells of fibrosis, was seen in our samples as reported \[[@pone.0187506.ref011], [@pone.0187506.ref012]\]. The presence of this smooth muscle protein is linked to contractile nature of myofibroblasts, which when persistent can cause distortion of tissue architecture, thus promoting disease pathogenesis \[[@pone.0187506.ref041]\]. We also demonstrated increased expression of TGFβ protein, a known inducer of myofibroblast transformation \[[@pone.0187506.ref042]\], \[[@pone.0187506.ref043]\], and provide evidence for the presence of an intrinsic trigger in the capsular tissue. It has been suggested that growth factors including TGFβ present in aqueous humor might trigger the fibrotic response \[[@pone.0187506.ref044]--[@pone.0187506.ref046]\]. However, our data is consistent with a recent study in which our group showed an increase in transcripts for matrix molecules as downstream targets of activated TGFβ pathway \[[@pone.0187506.ref047]\]. Saika et al. have also reported increased TGFβ protein expression in tissue from a trabeculectomy filtering bleb \[[@pone.0187506.ref048]\].
Accompanying increased expression of TGFβ in our samples was the decrease in ECM molecule decorin. Proteoglycan decorin is a naturally occurring TGFβ antagonist \[[@pone.0187506.ref018]\] that prevents fibrosis and improves surgical outcome of glaucoma filtration surgery in rabbits \[[@pone.0187506.ref049]\]. Additionally, we also observed a significantly decreased labelling with lumican, chondroitin sulfate and collagen III. Like decorin, lumican is also an endogenous inhibitor of TGFβ activity \[[@pone.0187506.ref019]\] which binds TGFβ receptor 1 (ALK5) and downregulates TGFβ signalling \[[@pone.0187506.ref050]\]. Although the mechanisms have not yet been defined, lumican has been implicated in regulating aqueous humor outflow in the trabecular meshwork \[[@pone.0187506.ref051], [@pone.0187506.ref052]\]. Furthermore, we and others have shown increased levels of MMPs in capsular tissue \[[@pone.0187506.ref047], [@pone.0187506.ref053]\]. It is known that degradation and cleavage of decorin and lumican is induced by matrix metalloproteinases (MMPs), a family of proteinases that can cleave extracellular matrix molecules \[[@pone.0187506.ref054], [@pone.0187506.ref055]\]. Degradation of these proteoglycans by MMPs may also explain the decreased decorin and lumican seen in our samples. Thus, besides increased expression, downregulation of these endogenous inhibitors might be another mechanism for activation of the profibrotic TGFβ signal in the capsular tissue.
Furthermore, decrease in decorin and lumican might influence the assembly of collagen in the inner capsular layer. In normal cornea lumican maintains orderly collagen fibril arrangement that is vital for corneal transparency \[[@pone.0187506.ref056]--[@pone.0187506.ref058]\]. In contrast down regulation of both decorin and lumican result in thicker and mal-oriented collagen fibres as well as decreased inter fibrillar distance in the corneas of knockout models \[[@pone.0187506.ref059], [@pone.0187506.ref060]\]. Morphology of opacified corneal stroma in knockout mice bears some resemblance to that seen in the inner layer of the excised capsules where compact, thick irregularly arranged collagen fibres are observed. Due to their role in collagen fibrillogenesis and wound healing, decreased expression of chondroitin sulfate glycosaminoglycans as seen in our capsules might also structurally alter the collagen scaffold \[[@pone.0187506.ref061], [@pone.0187506.ref062]\]. We also found significantly decreased expression of collagen III in the inner layer of our capsular samples. Fibrillar collagens form a major component of the ECM and diminished collagen III expression in haploinsufficient (Col III+/--) mice has been reported to accelerate cutaneous wound closure by promoting myofibroblast differentiation and increased scar formation \[[@pone.0187506.ref063]\].
We recognize that our study has limitations and further investigations will be needed in this regard. Capsules from functional AGV devices would probably be ideal second comparative controls for this study. However, functional capsules are not commonly excised and were not available for this study. Also, capsules examined in our study were mostly late excisions and expression changes in early stages of shunt failure could not be determined. It has been suggested that thickness and permeability of capsule around the implant is regulated by inflammatory/proliferative and apoptotic processes occurring during wound remodelling of the capsular tissue as a result of exposure to glaucomatous aqueous humor \[[@pone.0187506.ref064], [@pone.0187506.ref006]\]. However, in capsular tissue excised several years after implantation, we did not observe an inflammatory response. Furthermore, although clinical observation suggests that tenon's capsule thins with age and measured by optical coherence tomography (OCT) is variable in thickness \[[@pone.0187506.ref065]\]. Whether this change in physical characteristics of the capsule affects molecular changes is unclear. Nevertheless, tenon\'s fibroblasts derived from young versus old human eyes do show growth differences in vitro; however, wound closure/migration and collagen synthesis rates were reported to be similar \[[@pone.0187506.ref066]\]. Increasing the sample size while utilizing age matched capsular and tenon's tissue in future studies would likely give better statistical power to allow for correlation of expression changes with clinical parameters such as age, type of glaucoma, revision time and other variables. TGFβ is a pleiotropic molecule with complex roles, its relation to other pathways affecting glaucoma surgery such as inflammation and angiogenesis also requires further investigations \[[@pone.0187506.ref067], [@pone.0187506.ref068]\].
ECM has structural functions and increased expression of ECM molecules could be expected to explain the hydraulic resistance. Paradoxically, we found decreased expression of proteoglycans (decorin and lumican), GAGs (chondroitin sulfate) and collagen III. Together with increased TGFβ and αSMA this decrease of ECM molecules might indicate interplay of molecules potentially sustaining a profibrotic environment leading to myofibroblast contractility and tissue dysfunction. Such a role for the ECM as regulators of cell signalling is receiving increasing support \[[@pone.0187506.ref069], [@pone.0187506.ref070]\] and research in this area has demonstrated the importance of re-establishing a functional ECM in chronic wounds. Although our study points out an important role for ECM molecules, much remains
|
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] |
20 $\mu$s Raman laser pulse as a function of square root of the product of the beam intensities. The vertical error bars indicate the scatter range in the measurements, and the horizontal error bars indicate the uncertainty in the beam intensity due to laser power fluctuations[]{data-label="fig:F2ampexp"}](F2ampexp)
The results from a similar experiment demonstrating coherent oscillations between the $\left|2,2\right\rangle$ state and the $\left|2,0\right\rangle$ state are shown in Fig. \[fig:F2ampexp\]. The magnetic bias field applied in this experiment was 17 Gauss, resulting in a ground-state Zeeman splitting of 12 MHz, and a difference between the two-photon resonances of $\delta_{12}-\delta_{23}$ = 166 kHz. This splitting was large enough that with laser pulses of 20 $\mu$s duration (1/$\tau$=50 kHz), we were able to address the $\left|2,2\right\rangle\leftrightarrow\left|2,0\right\rangle$ transition separately from the $\left|2,-2\right\rangle\leftrightarrow\left|2,0\right\rangle$ transition.
For this experiment, $\Delta_{D_1}$ was set to -0.8 GHz, below resonance with the $F'=1$ excited state manifold. We maintained the ratio of laser intensities at $I_+/I_-=2.40$, which is the value that the model predicts will result in $\tilde\delta=0$. It is worthwhile to note that there is an upper limit to the intensities which can be used in these experiments, because of the necessity of avoiding incoherent exitation of the atoms. For the detunings and pulse durations used in these experiments, we typically only begin to see significant signs of incoherent excitation at intensities well above 200 mW/cm$^2$.
In both Fig. \[fig:F1ampexp\] and \[fig:F2ampexp\], the experimental results are in excellent agreement with the theoretical predictions. We emphasize that the same calibration values for the absolute intensity have been used for all the data sets presented in this Article, and there are no free parameters in any of the theoretical curves. We do note that there is some decrease in the amplitude of the oscillation at higher intensities. This could be due either to technical factors such as fluctuations in the beam intensities and drift in the magnetic bias field, or possibly small physical influences neglected in our current model, such as beam propagation effects. If the cause is one of the latter, it would prove to be an interesting subject for future study.
Phase Control in the $F=1$ Manifold
-----------------------------------
After having established that we can cause several complete Rabi oscillations between two Zeeman sublevels by applying an appropriately configured Raman pulse pair, we can approach more sophisticated problems in system control. A more demanding test of the protocols derived in Section \[sec:modeling\] is to attempt to demonstrate control of the relative phase of the states being coupled.
![ Applying two successive $\theta=\pi/2$ pulses with no phase shift results in complete transfer to the final state (a). Turning on only one of the Raman lasers causes a phase shift, rotating the pseudospin vector in $\phi$. For a $\phi=\pi$ rotation (b), the population returns to the initial state.[]{data-label="fig:Bloch"}](Bloch4)
One simple way of showing phase control in these pseudospin-1/2 systems is to perform a Ramsey-fringe type experiment, using a three step pulse sequence as depicted in Fig. \[fig:Bloch\]. The first step in this sequence is to apply a $\sigma^+$-$\sigma^-$ pulse pair which causes the pseudospin vector to precess 90$^\circ$ in the $\theta$ direction ($\pi/2$ effective pulse area). The second step is to apply only one or the other of the laser fields, which causes the pseudospin to precess in $\phi$ by an amount which depends on the magnitude of the Zeeman light shift and the duration of the pulse. The last step is to again apply a $\theta=\pi/2$ pulse. If neither of the fields is turned on in between the two $\theta=\pi/2$ pulses, after the final step all the population should end up in the target state. (Fig. \[fig:Bloch\]a) If a small phase shift is applied during the second step, the last operation will not move all of the population into the final state. If the $\phi$ phase shift is 180$^\circ$ ($\pi$), the action of the final pulse will be to actually return all of the population to the initial state. (Fig. \[fig:Bloch\]b)
![ Experimental results of applying the $\theta=\pi/2$, $\phi$, $\theta=\pi/2$ pulse sequence described above to the $\left|1,-1\right\rangle\:\leftrightarrow\:\left|1,1\right\rangle$ pseudospin system. Application of a $\phi$ changing pulse is shown to cause the expected oscillation in the final state population. The grey line is a theoretical prediction taking into account a nonzero $\tilde\delta$ caused by lowering the $\sigma_-$ beam intensity by 5%.[]{data-label="fig:F1phaseexp"}](F1phaseexp)
The results of an experiment implementing the pulse sequence of Fig. \[fig:Bloch\] are shown in Fig. \[fig:F1phaseexp\]. For this experiment, we used the $\left|1,-1\right\rangle\:\leftrightarrow\:\left|1,1\right\rangle$ system, with the laser detunings set to $\Delta_{D_1}=0$ as in the coherent oscillation experiment of Fig. \[fig:F1ampexp\] above. The $\theta=\pi/2$ pulses were 5 $\mu$s in duration, separated by 10 $\mu$s. After the first $\theta=\pi/2$ pulse, we left on either the $\sigma^+$ or the $\sigma^-$ laser field for a duration of 0-10 $\mu$s in order to cause the desired phase shift. For the data shown, the ratio of $I_+/I_-$ was offset by 5% from the values which would make $\tilde\delta=0$, in order to make the sign difference in the rotation caused by the $\sigma^+$ and $\sigma^-$ beam in this configuration explicitly apparent. The theoretical curve in the figure has been shifted accordingly, and is in reasonable agreement with the experimental data. This confirms that phase control of the system is indeed possible, and occurs as predicted by the model.
Two-photon Lineshape in the $F=2$ Manifold {#ssec:2pdet}
------------------------------------------
In the previous Sections we have focused on Raman-coupling of two selected states out of a Zeeman manifold. The distinction made in Section \[ssec:F=2\] between treating the $\left|2,2\right\rangle$, $\left|2,0\right\rangle$, and $\left|2,-2\right\rangle$ states as either a pseudospin-1 system at zero magnetic field, or a pair of pseudospin-1/2 systems in the presence of a large magnetic field is, of course, an oversimplification. At moderate magnetic fields, using pulses of sufficient bandwidth, this trio of states in the $F=2$ manifold can be coupled simultaneously even though the two-photon transitions are not quite degenerate. This allows for the intriguing possibility of using a single laser pulse pair to distribute population into all three states, where the fraction of the population in each state and their relative phase can be controlled by varying the splitting between $\delta_{12}$ and $\delta_{23}$ with the magnetic field, and adjusting the two-photon detuning with respect to these resonances in a manner determined by numerical modeling of the system.
![ Fractional population transferred to $\left|2,0\right\rangle$ and $\left|2,-2\right\rangle$ from a BEC initially in the $\left|2,2\right\rangle$ state by a 20 $\mu$s Raman laser pulse for different choices of the two-photon detuning $\delta$. The magnitude and ratio of the intensities were set for an effective $\theta=1.5\pi$ pulse area on two-photon resonance with the $\left|2,2\right\rangle\:\leftrightarrow\:\left|2,0\right\rangle$ transition, with the detuning of the beams set at $\Delta_{D_1}$ = -800 MHz. The applied magnetic bias field was 17 Gauss, for which $\delta_{12}-\delta_{23}$=166 kHz.[]{data-label="fig:2PDplot"}](2PDplot)
The results of an experiment demonstrating the two-photon detuning dependence of the fractional transfer to the $\left|2,0\right\rangle$ and $\left|2,-2\right\rangle$ states are shown in Fig. \[fig:2PDplot\]. The applied magnetic field used for that data set is still relatively large, such that the energy separation of the two photon resonances is several times the pulse bandwidth. The intensities used were I$_+$= 30.6 mW/cm$^2$ and I$_-$= 12.8 mW/cm$^2$, which are appropriate to make $\tilde\delta_{23}=0$, with an effective two-photon pulse area of 1.5 $\pi$ for resonance with that transition. It should be noted that in this plot the maximum vertical scale for the
|
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] |
AND_68 = EutranBands.BAND_68;
public static final int BAND_70 = EutranBands.BAND_70;
public static final int BAND_71 = EutranBands.BAND_71;
public static final int BAND_72 = EutranBands.BAND_72;
public static final int BAND_73 = EutranBands.BAND_73;
public static final int BAND_74 = EutranBands.BAND_74;
public static final int BAND_85 = EutranBands.BAND_85;
public static final int BAND_87 = EutranBands.BAND_87;
public static final int BAND_88 = EutranBands.BAND_88;
/** @hide */
private EutranBand() {};
}
/**
* Frequency bands for CDMA2000.
* http://www.3gpp2.org/Public_html/Specs/C.S0057-E_v1.0_Bandclass_Specification.pdf
* @hide
*
* TODO(yinxu): Check with the nexus team about the definition of CDMA bands.
*/
public static final class CdmaBands {
public static final int BAND_0 = 1;
public static final int BAND_1 = 2;
public static final int BAND_2 = 3;
public static final int BAND_3 = 4;
public static final int BAND_4 = 5;
public static final int BAND_5 = 6;
public static final int BAND_6 = 7;
public static final int BAND_7 = 8;
public static final int BAND_8 = 9;
public static final int BAND_9 = 10;
public static final int BAND_10 = 11;
public static final int BAND_11 = 12;
public static final int BAND_12 = 13;
public static final int BAND_13 = 14;
public static final int BAND_14 = 15;
public static final int BAND_15 = 16;
public static final int BAND_16 = 17;
public static final int BAND_17 = 18;
public static final int BAND_18 = 19;
public static final int BAND_19 = 20;
public static final int BAND_20 = 21;
public static final int BAND_21 = 22;
/** @hide */
private CdmaBands() {}
}
/**
* Frequency bands for NGRAN
* https://www.etsi.org/deliver/etsi_ts/138100_138199/13810101/15.08.02_60/ts_13810101v150802p.pdf
* https://www.etsi.org/deliver/etsi_ts/138100_138199/13810102/15.08.00_60/ts_13810102v150800p.pdf
*/
public static final class NgranBands {
/** 3GPP TS 38.101-1, Version 16.2.0, Table 5.2-1: FR1 bands */
public static final int BAND_1 = android.hardware.radio.V1_5.NgranBands.BAND_1;
public static final int BAND_2 = android.hardware.radio.V1_5.NgranBands.BAND_2;
public static final int BAND_3 = android.hardware.radio.V1_5.NgranBands.BAND_3;
public static final int BAND_5 = android.hardware.radio.V1_5.NgranBands.BAND_5;
public static final int BAND_7 = android.hardware.radio.V1_5.NgranBands.BAND_7;
public static final int BAND_8 = android.hardware.radio.V1_5.NgranBands.BAND_8;
public static final int BAND_12 = android.hardware.radio.V1_5.NgranBands.BAND_12;
public static final int BAND_14 = android.hardware.radio.V1_5.NgranBands.BAND_14;
public static final int BAND_18 = android.hardware.radio.V1_5.NgranBands.BAND_18;
public static final int BAND_20 = android.hardware.radio.V1_5.NgranBands.BAND_20;
public static final int BAND_25 = android.hardware.radio.V1_5.NgranBands.BAND_25;
public static final int BAND_28 = android.hardware.radio.V1_5.NgranBands.BAND_28;
public static final int BAND_29 = android.hardware.radio.V1_5.NgranBands.BAND_29;
public static final int BAND_30 = android.hardware.radio.V1_5.NgranBands.BAND_30;
public static final int BAND_34 = android.hardware.radio.V1_5.NgranBands.BAND_34;
public static final int BAND_38 = android.hardware.radio.V1_5.NgranBands.BAND_38;
public static final int BAND_39 = android.hardware.radio.V1_5.NgranBands.BAND_39;
public static final int BAND_40 = android.hardware.radio.V1_5.NgranBands.BAND_40;
public static final int BAND_41 = android.hardware.radio.V1_5.NgranBands.BAND_41;
public static final int BAND_48 = android.hardware.radio.V1_5.NgranBands.BAND_48;
public static final int BAND_50 = android.hardware.radio.V1_5.NgranBands.BAND_50;
public static final int BAND_51 = android.hardware.radio.V1_5.NgranBands.BAND_51;
public static final int BAND_65 = android.hardware.radio.V1_5.NgranBands.BAND_65;
public static final int BAND_66 = android.hardware.radio.V1_5.NgranBands.BAND_66;
public static final int BAND_70 = android.hardware.radio.V1_5.NgranBands.BAND_70;
public static final int BAND_71 = android.hardware.radio.V1_5.NgranBands.BAND_71;
public static final int BAND_74 = android.hardware.radio.V1_5.NgranBands.BAND_74;
public static final int BAND_75 = android.hardware.radio.V1_5.NgranBands.BAND_75;
public static final int BAND_76 = android.hardware.radio.V1_5.NgranBands.BAND_76;
public static final int BAND_77 = android.hardware.radio.V1_5.NgranBands.BAND_77;
public static final int BAND_78 = android.hardware.radio.V1_5.NgranBands.BAND_78;
public static final int BAND_79 = android.hardware.radio.V1_5.NgranBands.BAND_79;
public static final int BAND_80 = android.hardware.radio.V1_5.NgranBands.BAND_80;
public static final int BAND_81 = android.hardware.radio.V1_5.NgranBands.BAND_81;
public static final int BAND_82 = android.hardware.radio.V1_5.NgranBands.BAND_82;
public static final int BAND_83 = android.hardware.radio.V1_5.NgranBands.BAND_83;
public static final int BAND_84 = android.hardware.radio.V1_5.NgranBands.BAND_84;
public static final int BAND_86 = android.hardware.radio.V1_5.NgranBands.BAND_86;
public static final int BAND_89 = android.hardware.radio.V1_5.Ngran
|
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13,
285,
33005,
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] |
Trump, and Racism in America
Feb 08, 2018By Mark Redfern
For Under the Radar's 15th annual Artist Survey we emailed some of our favorite artists a few questions relating to the last year. We asked them about their favorite albums of the year and their thoughts on various notable 2017 news stories involving either the music industry or world events, as well as some quirkier personal questions. MoreWelcome to Global Money Bitcoin
GlobalMoney is an international wealth management company that offers individuals and groups the opportunity to participate in some of the most exciting global investments available. Our team has put together a portfolio of opportunities that provides highly lucrative returns on investments.
.
Overview
The key to our long-term financial success is working hard to identify and develop.
WHY USE GLOBALMONEY?
GlobalMoney is a relatively new form of currency that is just beginning to hit the mainstream, but many people still don't understand why they should make the effort.
HOW TO STORE YOUR GLOBALMONEY?
GlobalMoney wallets store the private keys that you need to access a GlobalMoney address and spend your funds. They come in different forms, designed for different types of device.
HOW CAN I BUY GLOBALMONEY?
You've learned the basics about GlobalMoney, the next step is to get some GlobalMoney. But how? This guide will tell you what you need to know.
VERY WELL DOCUMENTED
You can pay for them in a variety of ways, ranging from hard cash to credit and debit cards to wire transfers, or even with other cryptocurrencies, depending on who you are buying them from and where you live.
About
Best Opportunity awaites for you.. Start Bitcoin Earning Today!
WHO WE ARE.?
WHY WE ARE.?
Global Money is not owned by any single person or entity, we are a team of experts, entrepreneurs, professionals, network marketers, and programming geeks who have all come to together to launch a very simple business around a very complex industry. Anyone can join Single Leg Bitcoin Network and begin earning a passive income by taking advantage of our expertise in Bitcoin mining and other Bitcoin related services.
Global Money is a peer-to-peer Internet currency that enables instant, near-zero cost payments to anyone in the world. Global Money is an open source, global payment network that is fully decentralized without any central authorities. Mathematics secures the network and empowers individuals to control their own finances. Global Money features faster transaction confirmation times and improved storage efficiency than the leading math-based currency.
OUR MISSION
Our mission is to break the Financial Barriers in the life of every Business Associate. We strive to remove unemployment, inflation by providing alternate income opportunities. Turning Point is offering unique business opportunity with minimum investment and zero risk.
WE LOVE
We offer a clear Vision for our business which is underpinned by strong core values of Dependability and Customer Service. This is demonstrated by our working practices which show we are progressive, different and client focussed.
Key features
Get Started
Introducing Global Money
Join the system with just $50 and $100 one time fee!
Get your unique ReferenceID and start promoting it online & to your friends! No limitations to the people you can invite to the system!
Earn upto $1500 for every user you bring to the system 12th level of your downline, that means you earn money also from the members which are invited from your downlines!!!
Benefits
Awesome features
INFORMATIONAL
Inform users to protect them from common mistakes.
OPEN SOURCE
All transactional processes are open to public scrutiny and inspection.
TRANSPARENCY
Display transparent alerts and events regarding the Bitcoin network.
OPPORTUNITY
great opportunity for Bitcoin owners to invest and increase profit in a highly secured environment.# Encryption
As of Jan. 2020 you can set up an encryption key in your config which will encrypt all images stored on [external storage](/rtfm/CONFIG.md#storage-controllers)
The files on the PictShare server are not encrypted, only the ones on external storage providers, eg if you want to use S3 as storage.
## Dependencies
To be able to use encryption you'll need the following extensions:
- mb-string (`apt-get install php-mbstring`)
- libsodium (`apt-get install php-libsodium`)
Since only files on [storage controllers](/rtfm/CONFIG.md#storage-controllers) are encrypted, you'll need to configure at least one.
## Preparation
First you'll need to generate a key and encode it in base64.
The easiest way to get it would be to run this command:
`php -r "echo base64_encode(sodium_crypto_secretstream_xchacha20poly1305_keygen());"`
This will output something like `SSdoJvp10ZvOY5v+vAcprxQKjNX1AzD52cAnFwr6yXc=`
Now put this output in your /inc/config.inc.php like this:
`define('ENCRYPTION_KEY','SSdoJvp10ZvOY5v+vAcprxQKjNX1AzD52cAnFwr6yXc=');`
**Warning: If you change or lose the ENCRYPTION_KEY, all encrypted data will be unrecoverably lost**
# How it works
If you have everything running you can upload a new image and it will get encrypted and uploaded to your storage container(s). This means you could even host on untrusted servers/buckets since nobody without the key will be able to decrypt it.
If you have uploaded a few files and see them on your storage container (eg S3) you'll notice the file has the '.enc' extension.
When you now wipe your PictShare instances local data folder and request the file again via the URL, the storage controller will pull the encrypted file, decrypt it and save it locally (unencrypted)pim_connector:
steps:
file_reader:
invalid_item_columns_count: '期望获取 %totalColumnsCount% 列，实际获取了 %itemColumnsCount% 列。路径：%filePath%:%lineno%'
job_execution.summary:
write: 已写入
skip: 已跳过
create: 已创建
process: 已处理
update_products: 已更新产品
process_products: 已处理产品
skip_products: 已跳过产品
displayed: 已显示第一次警告
charset_validator:
title: '文件编码：'
skipped: 已跳过，在白名单中扩展
product_skipped_no_diff: 已跳过产品（无差异）
product_skipped_no_associations: 跳过的产品（没有检测到任何关联）
product_model_skipped_no_diff: 跳过的产品模型（无差异）
item_position: 读取行
skipped_in_root_product_model: 跳过有父级产品模型的产品模型
skipped_in_sub_product_model: 跳过没有父级产品模型的产品模型
Development of headspace SPME method for analysis of volatile organic compounds present in human biological specimens.
In recent years, interest has increased regarding the identification of volatile organic compounds (VOCs) for metabolic profiling, human scent identification of the living and deceased, and diagnostic potentials for certain diseases that are known for its association with distinct odor. In this study, a method has been developed that is capable of sampling, identifying, and differentiating the VOCs present in various biological specimens of forensic importance (blood, breath, buccal cells, and urine) taken from the same individuals. The developed method requires a pretreatment step to remove targeted VOCs from the sampling apparatus prior to sampling of the individual specimens. The VOCs collected from the biological specimens were characterized by solid-phase microextraction and gas chromatography/mass spectrometry with ratios of the most abundant and frequent VOCs compared using qualitative and semiquantitative methods. Blood, breath, and buccal cells required extraction procedures ranging from 18 to 21 h in order to optimize the limit of detection, which averaged 5-15 ng across these specimens. The optimal method for measuring urine VOCs was complete in less than an hour; however, the limit of detection was higher with a range of 10-40 ng quantifiable. The demonstrated sensitivity and reproducibility of the methods developed allow for population studies of human scent VOCs from various biological specimen collection kits used in the forensic and clinical fields.Trải Thảm làm sao để cho ngôi nhà thêm phần sang trọng.
|
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] |
ulario de registro
En algunos hoteles es posible que tengas que rellenar un formulario en la recepción, das Formular (das foa-mu-laa), como parte del proceso de registro. La recepcionista te entregará el formulario, diciendo algo así:
Bitte füllen Sie dieses Formular aus. (bit-te fiul-len sii dii-ses foa-mu-laa aus; por favor, complete este formulario)
La información que se pide en el formulario varía; en la mayoría de los casos bastan tu nombre y tu dirección, pero también es posible que te pidan la siguiente información:
• Name/Vorname (na-me/foa-na-me; apellido/nombre de pila)
• Straße/Nummer (Nr.) (shtraa-se/num-mea; calle/número)
• Postleitzahl/Wohnort (post-lait-tsaal/voon-oat; código postal/ciudad)
• Geburtsdatum/Geburtsort (gue-buats-da-tum/gue-buats-oat; fecha de nacimiento/lugar de nacimiento)
• Nationalität (na-tsi-o-na-li-taet; nacionalidad)
• Beruf (be-ruf; ocupación)
• Passnummer (pas-num-mea; número de pasaporte)
• Kraftfahrzeugkennzeichen (craft-faa-tsoic-quen-tsai-jen; número de matrícula del coche)
• Ort/Datum (oat/da-tum; lugar/fecha)
• Unterschrift (un-tea-shrift; firma)
Pedir el juego de llaves
Cuando te hayas registrado, la recepcionista te indicará el número de tu habitación:
Sie haben Zimmer Nummer 203. (sii ja-ben tsim-mea num-mea tsvai-jun-deat-drai; su habitación es la número 203)
El número de la habitación suele estar escrito en la llave, como en los hoteles de la mayor parte del mundo.
No olvides el equipaje
Lo más probable es que viajes con algún tipo de equipaje, **das Gepäck** (das gue-paec). Tu equipaje podría ser **der Koffer** (dea cof-fea; maleta) o quizá **die Koffer** (dii cof-fea; maletas). No es un error: la única diferencia entre el singular y el plural de "maleta" es el artículo.
---
En algunos hoteles, por lo general en las ciudades pequeñas, es posible que tengas que dejar la llave en la recepción en vez de llevarla contigo cuando sales. Al regresar al hotel, puedes utilizar cualquiera de estas frases para pedir la llave:
• Können Sie mir bitte den Schlüssel für Zimmer... geben? (coen-nen sii mia bit-te den shlius-sel fiua tsim-mea gue-ben; ¿podría darme la llave de la habitación número...?)
• Den Schlüssel für Zimmer... bitte. (den shlius-sel fiua tsim-mea bit-te; la llave de la habitación número..., por favor)
Preguntar por los servicios que ofrecen
También es posible que quieras averiguar qué tipo de servicios ofrece el hotel: ¿Tiene la habitación teléfono y minibar? ¿Tiene el hotel servicio de lavandería?
Tu habitación
Si quieres preguntar sobre servicios específicos en tu habitación, empieza con la frase:
Hat das Zimmer...? (jat das tsim-mea; ¿la habitación tiene...?)
Luego, finaliza la frase con cualquiera de los siguientes elementos sobre los que quizá quieras preguntar:
•...Kabelfernsehen? (ca-bel-fean-se-jen; ¿...televisión por cable?)
•...Satellitenfernsehen (sa-tel-li-ten-fean-se-jen; ¿...televisión vía satelital?)
•...ein Telefon? (ain te-le-fon; ¿...teléfono?)
•...eine Minibar (ai-ne mi-ni-bar; ¿...minibar?)
Si lo único que quieres es llegar a tu habitación y descansar, puedes asegurarte de que el personal de servicio no te moleste colocando un letrero con el siguiente mensaje en la puerta (lo encontrarás en algún lugar de la habitación):
Bitte nicht stören! (bit-te nijt shtoe-ren; ¡por favor, no molestar!)
Desayuno en el hotel
---
En casi todos los grandes hoteles ofrecen un desayuno de tipo buffet, en el que puedes escoger todo tipo de alimentos, como cereales, huevos, diversos panes y zumos, jamones, quesos, etc. Sin embargo, en las ciudades o los hoteles pequeños, es posible que te sirvan lo que solía ser el desayuno alemán típico: panecillos, panes, mermelada, huevos pasados por agua y una selección de fiambres y quesos. Así pues, si no puedes prescindir de los huevos revueltos por la mañana, ¡tal vez tengas que pedirlos de forma adicional! (Para aprender a hacerlo, consulta el capítulo 5.)
El hotel
Es posible que el hotel ofrezca una variedad de servicios. Por lo general, estos servicios están especificados en un folleto o carta que encontrarás en la habitación. Sin embargo, si no encuentras una lista de servicios, puedes llamar a la recepción y preguntar:
Hat das Hotel...? (jat das jo-tel; ¿el hotel tiene...?)
Luego puedes preguntar por cualquiera de los siguientes servicios finalizando la frase anterior con:
•...eine Sauna? (ai-ne sau-na; ¿...sauna?)
•...ein Schwimmbad? (ain shvim-bad; ¿...piscina?)
•...ein Fax? (ain facs; ¿... fax?)
•...einen Wäschedienst? (ai-nen vae-she-diinst; ¿...servicio de lavandería?)
•...eine Klimaanlage? (ai-ne cli-ma-an-la-gue; ¿...aire acondicionado?)
•...eine Hotelgarage? (ai-ne jo-tel-ga-ra-she; ¿...garaje?)
•...eine Parkplatz? (ai-nen parc-plats; ¿...estacionamiento?)
Y éstas son las preguntas que te permitirán informarte sobre el desayuno y el servicio de habitaciones:
• Wann wird das Frühstück serviert? (van vird das friu-shtiuc sea-viiat; ¿a qué hora sirven el desayuno?)
• Gibt es Zimmerservice? (guibt es tsim-mea-sea-vis; ¿hay servicio de habitaciones?)
Algo importante que te facilitará la vida en el hotel es poder preguntar si has recibido alguna llamada telefónica. La pregunta que debes hacer es:
Hat jemand eine Nachricht für mich hinterlassen? (jat ie-mand ai-ne naj-rijt fiua mij jin-tea-las-sen; ¿me dejó alguien algún mensaje?)
Hablando se entiende la gente
**Pista 29:** Klaus y Ulrike Huber llegan a su hotel en Austria. Estacionan su coche en la entrada y van a la recepción para registrarse.
Klaus: | Guten Abend! Mein Name ist Huber
|
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] |
mutagenesis method, following the experimental procedure of Zhang *et al*.[@b35]. The mutagenic primer sequences for engineering the GVE2 HNHE N109A and H118A mutants were 5′-\*CGATTAGATATGGAC[GC]{.ul}CCTGCAATCGTTATGC-3′, and 5′-\*CGTTATGCCAAGCCTGC[GC]{.ul}TAACAGAAAGACGGCGG (\* indicates that C is phosphorylated and the underscored bases are mutation bases), respectively. The mutations were verified by sequencing.
Protein expression and purification of the wild type and mutant GVE2 HNHEs
--------------------------------------------------------------------------
The wild type and mutant GVE2 HNHEs were over-expressed, purified, and quantified as described previously[@b21]. For biochemical analysis, the wild type and mutant GVE2 HNHE proteins were dialyzed in a storage buffer (50 mM Tris-HCl pH 8.0, 0.1 mM EDTA (ethylenediaminetetraacetic acid), 1 mM DTT (dithiothreitol) and 50% glycerol). For crystallization assay, the wild type GVE2 HNHE protein was dialyzed against a buffer containing 20 mM Tris-HCl pH 8.0, 50 mM NaCl, and 2 mM DTT, then concentrated to 25 mg/ml.
Crystallization of GVE2 HNHE
----------------------------
Crystallization was performed by sitting-drop vapor diffusion at 293 K. The crystal of GVE2 HNHE with 10 mM Zn^2+^ (final concentration) was grown in a reservoir solution containing 0.1 M HEPES, 0.2 M sodium chloride, pH 7.5 and 25% (w/v) polyethylene glycol 4000. To obtain the crystal structure of GVE2 HNHE with Mn^2+^, 10 mM Mn^2+^ (final concentration) was added into the protein solution instead of Zn^2+^. The heavy-atom derivative crystals were obtained by soaking in 10 mM HgCl~2~ for 3 sec. All the crystals obtained were subjected to a post-crystallization procedure by dehydrating by evaporation against air for 5 min at 297 K, and then flash frozen in liquid nitrogen.
Data collection and structure determination
-------------------------------------------
Diffraction data of GVE2 HNHE with Zn^2+^, Mn^2+^ and Hg-SAD were collected at the BL17U beamline of Shanghai Synchrotron Radiation Facility, the beamline BL1A and BL5A at the Photon Factory in Japan and the beamline 1W2B at Beijing Synchrotron Radiation Facility, respectively. Data were integrated and scaled with the HKL2000 package[@b36]. The positions of heavy atoms and the initial phases of GVE2 HNHE were calculated by SAD using HKL2MAP[@b37]and Phenix[@b38] with a mercury derivative data set. The structure of GVE2 HNHE with Mn^2+^ was determined by molecular replacement with the Phaser programmer in the CCP4 programed suite[@b39][@b40]. In addition, according to the anomalous difference Fourier maps calculated with a data set collected at a wavelength of 1.8 Å, the location of Mn^2+^ was confirmed. The structure refinements were carried out with Refmac and Phenix[@b38][@b41]. Model building was carried out using Coot[@b42]. MolProbity was used to validate the two structures[@b43]. A summary of data collection and final refinement statistics are listed in [Table 1](#t1){ref-type="table"}.The program Pymol (<http://www.pymol.org>) was used to prepare the crystal structure figures of GVE2 HNHE. The sequence alignment figure ([Fig. 1A](#f1){ref-type="fig"}) was prepared using ESPript[@b44].
Accession numbers
-----------------
The atomic coordinates and structure factors have been deposited in the PDB database under accession codes 5H0M and 5H0O.
Circular dichroism measurements
-------------------------------
The wild type GVE2 HNHE and its mutants harboring the H93A, N109A, and H118A substitutions were dialyzed into 50 mM PBS (phosphate-buffered saline) pH7.5 for CD analysis. The CD spectra were recorded at 20 °C from 200 to 250 nm using a J-810 spectropolarimeter and a cuvette of path length 0.2 cm. The proteins were at a concentration of 1.5 mg/ml. The spectra were collected at a scanning rate of 50 nm/min, and triplicate spectrum readings were collected per sample. The CD spectral data were reported as mean residue ellipticity \[θ\], and the CD wavelength spectra were smoothed as described by Savitsky and Golay[@b45].
Thermal stability of the wild type and mutant GVE2 HNHEs was examined by the following changes in the spectrum in CD analysis with increasing temperature (30--90 °C). The proteins were at a concentration of 1.5 mg/ml. A single wavelength (222 nm) was selected to monitor the GVE2 HNHE protein structure, and the signal at that wavelength was recorded continuously as the temperature was increased. The CD wavelength spectra were smoothed using Origin software.
CD spectra for monitoring Mn^2+^- or Zn^2+^-dependent structural changes in GVE2 HNHE were recorded after incubation of the enzyme with different concentrations (2 nM, 10 nM, 50 nM, 200 nM, 1 mM and 5 mM) of Mn^2+^ or Zn^2+^ on ice for 5 min. Binding constants were determined from the plot of ellipticity changes at a wavelength of 222 nm with an increasing metal ion concentration. Apparent dissociation constants (*K*~d~) were determined by fitting the curves to Hill analysis using Origin software.
DNA nicking assays
------------------
DNA nicking assays were carried out in the reactions (20 μl) containing 200 ng the plasmid pET-30a DNA, 20 mM Tris-HCl pH 8.0, 1 mM DTT, GVE2 HNHE or its mutant (H93A, N108A or H119A) at various concentrations (5, 20, 50, 100, 200 or 400 nM), 2 mM MnCl~2~, 0.1 mg/ml BSA (bovine serum albumin) and 10% glycerol. The reactions were performed at 60 °C for 15 min. The reactions were terminated with the addition of EDTA at a final concentration of 100 mM and 1 × DNA loading buffer (New England Biolabs). The nicking product was analyzed by electrophoresis through 1% agarose gels.
Additional Information
======================
**How to cite this article:** Zhang, L. *et al*. Structural and functional characterization of deep-sea thermophilic bacteriophage GVE2 HNH endonuclease. *Sci. Rep.* **7**, 42542; doi: 10.1038/srep42542 (2017).
**Publisher\'s note:** Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
We thank Dr. Maozhi Hu (Test Center of Yangzhou University) for their assistance in CD measurement and data analysis. We also thank Dr. Shengquan Yang (Department of Food Science and Engineer, Yangzhou University) for providing his assistance in protein purification. We also thank Tabitha Gillman (University of Alberta) for comments on an earlier version of the manuscript. We are grateful to Mei Li and Zengqiang Gao and the staff of beamline BL17U at the Shanghai Synchrotron Radiation Facility, the staff of beamline 1W2B at Beijing Synchrotron Radiation Facility and the staff of beamline BL1A and BL5A at the Photon Factory, KEK (Tsukuba, Japan) for technical support. This work was supported by the National Natural Science Foundation of China Grant (No. 41306131), the Natural Science Foundation Grant for College and University of Jiangsu Province, China (No. 13KJB180029), the Provincial Natural Science Foundation Grant of Jiangsu Province, China (No. BK20130440), the State Key Laboratory of Microbial Technology Open Projects Fund (No. M2016-09) and Open Research Fund Program of the State Key Laboratory of Virology of China (No. 2016KF006) to L.Z., the National Natural Science Foundation of China Grant (No. 31270791 and No. U1432241) to Y.G., the Postgraduate Research Innovation Grant of Jiangsu Province, China (No. KYLX16_1400) to Y.H., and the Yangzhou University College Student Science and Technology Innovation Grant to X.Z.
The authors declare no competing financial interests.
**Author Contributions** L.Z. and Y.G. contributed to the initial design of this project. D.X. and X. Zheng. solved the crystal structures of GVE2 HNHE. Y.C., X. Zhu., M.R. and T.W. conducted biochemical experiments. L.Z., Y.G., Y.S., X.C. and K.M. prepared and revised the manuscript of this publication.
![The crystal structures of GVE2 HNHE.\
(**A**) Sequence alignment of GVE2 HNHE and Gme HNHE. Strictly conserved and conservatively substituted residues are marked with red and yellow backgrounds. The secondary structure elements at the top and bottom are from our structure
|
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] |
Norwich Pride 2019
27 July 2019The ForumNorwich Pride 2019 the 11th Norwich Pride in celebration of 50 years since the Stonewall riots PARADE Norwich Pride are proud that the Norwich Pride Parade has always been a People’s Parade that anyone can join in. Over the last couple of years it has got so huge that we’ve become concerned about [...]
Salisbury Pride 2019
27 July 2019Salisbury City CentreSalisbury will be once again showing it's Pride colours on the 27th July 2019. Starting outside of The Salisbury Playhouse and Spire FM and slowly meandering around Our Historic City. After the Parade a Celebration Zone comes to life for the rest of the night, which will include Drag/Comedy Acts, [...]
Brighton Pride Street Party 2019
03 August 2019St. James StThe Pride Village Party (PVP) 2019 is once again being run and managed by Brighton Pride Community Interest Company (CIC) with the full support of Brighton & Hove City Council. This is a spectacular two day fundraising event, the Pride Village Party sees St James Street and the city’s iconic [...]
Leeds Pride 2019
04 August 2019Lower BriggateLeeds Gay Pride 2019 Yorkshire's Biggest celebration of Lesbian, Gay, Bisexual and Trans* life. Sunday 4th August 2019 While everyone coming along is there to unite and enjoy a fantastic day, we would really appreciate your co-operation regarding various safety matters. Access to Lower Briggate [...]
Pride in Surrey 2019
10 August 2019Woking Park, SurreyPride in Surrey is here to educate, celebrate and connect the LGBTQ+ community of Surrey and their allies. Everyone is welcome! Surrey's 1st Pride event is coming and the Pride in Surrey team are so proud to be hosting such an incredible day for the whole of Surrey! More to follow
Swindon and Wiltshire Pride 2019
Perthshire Pride 2019
10 August 2019Perth Concert Hall, Perth, ScotlandPerthshire Pride 2019 will be a great event for everyone to celebrate the LGBT+ community. Starting with a march, the day will have something for everyone; youth zone, outside stage with live music, BBQ, dancing and much more. Come and enjoy beautiful Perthshire with all its beautiful people.
Doncaster Pride 2019
17 August 2019Sir Nigel Gresley SquareDoncaster gears up to celebrate the 13th Doncaster Pride, main event is on Saturday the 17th August This is a free event PARADE Start & Finish The start and finish will be in front of the Doncaster Council Building on Waterdale DN1 3BU. The Procession will depart at 1pm (please start to gather [...]
Pride In Newry 2019
22 August 2019McClelland ParkHosting UK and Ireland Pride 2019, Pride in Newry will bring a wash of colour to the border town of Newry from 22nd - 31st Aug 2019 with the main Parade and free outdoor concert on 31 Aug 2019. More information to be made available nearer the time via website and social media (@prideinnewry)
Manchester Pride 2019
23 August 2019ManchesterThe Manchester Pride Festival 2019 takes place on 23rd - 26th August 2019 The four-day event, known as The Big Weekend, has been around for more than 25 years being know at different times by various names including Pride, Mardi Gras and The Big Weekend and has traditionally taken place only in [...]
Cornwall Gay Pride 2019
24 August 2019The KillacourtCornwall Pride Parade starting at midday, followed by a family Picnic in the Park from event with stalls, food and free entertainment. Ticketed event in the evening at Tall Trees on Tolcarne Road (over-18 only) with local acts supporting a national headliner, Union J. Parade Our parade formally [...]
Foyle Pride 2019
24 August 2019Train StationJoin the Foyle Pride parade to help represent the LGBT+ community in the Foyle area and across the North West, and campaigning in solidarity with the global LGBT+ community. More to follow
Reading Pride 2019 LoveUnites
31 August 2019King's MeadowReading Pride 2019 work throughout the year to promote equality and to celebrate the very best of the LGBT+ community. Get involved with this year's FREE-to-enter Pride Parade & Festival and share your stories of #LoveUnites. More details will be available later in the year.
September 2019
Totnes Pride 2019
07 September 2019TotnesProud2Be's annual community Pride event open to everyone. Totnes Pride host a high street procession, a free family friendly day event and a fun filled after party (16+). The event takes place on the 1st Saturday in September every year. More to follow
Milton Keynes Pride 2019
14 September 2019Campbell ParkMilton Keynes Pride goal with Pride:MK is to engage and empower the local LGBTQ+ community. We will do that by creating a free and safe space to celebrate our contributions to Milton Keynes, by improving visibility and education around LGBTQ+ issues, and by building healthy relationships between [...]Morphological conversion of 13 strains of three dimorphic fungi in tap and stream water.
Various strains of Sporotrichum schenckii, Histoplasma capsulatum and Paracoccidioides brasiliensis show partial to complete (ca 70%) conversion to yeast when the mycelial culture is grown on Sabouraud's dextrose agar at 25degreesC and palced in tap or stream water at 37degreesC. Conversion (ca 70%) to mycelial phase occurs when the yeast culture is grown on brain heart infusion agar at 37degreesC and then placed in tap or stream water at 25degreesC. It was observed that, with the dimorphic organisms and strains tested, enriched medium is not necessary for partial conversion to either phase because it occurs in tap and stream water. The change in morphology is assumed to be principally due to temperauture change, as reported for Blastomyces dermatitidis and H. capsulatum by other workers.Jaboka
Jaboka (), is a town and union council(NO.9) of Okara District in the Punjab province of Pakistan.
It is located at 30°57'38N 73°27'10E with an altitude of 161 metres (531 feet), and is one of the larger towns of Okara district. Jaboka is a commercial and educational hub for more than 20 villages around it. It has markets of garments clothes,cosmetics,jewelry and shoes market
People living in the village's location 70 to 80 years previously were called Jaboka, from which the village took its name. It has two ancient buildings, which were constructed in the early 20th century. It has population of about 60,000.
There are different castes in the village: the majority of the population of Jaboka are Raos, Ranas, Arain, Wattos and Kharals.
There are four government schools in Jaboka, two for boys and two for girls. There is also a Baharia Foundation College (BFC), found on 15 April 2013, and a private school affiliated with the Punjab Education Foundation (PEF), Shaheen-e-Millat Model Secondary School, established in 1994.
References
Category:Union councils of Okara DistrictResults From Week One of Thursday Thunder at Atlanta Motor Speedway
Thursday, June 2, 2011
The 14th season launched with eight classes of feature racing, first time winners and one competitor continuing to set Thursday Thunder history. In addition to the action-packed racing, fans were also treated to the Jersey Thunder Jet Car.
Drivers were also eager for a win which would provide them an entry into the Labor Day Invitational, which is AMS' version of an All-Star race for Bandolero / Legends cars. The race will be held on Sept. 2, 2011 during the AdvoCare 500 NASCAR race weekend.
Bill Plemons, Jr. started out front for the Masters feature. On the first lap in the third turn, Skip Nichols hooked the rear of Plemons turning him around and giving Nichols the lead. Nichols led every circuit to post his 30th career Thursday Thunder win and continue to stretch his lead of having the most Thursday Thunder wins in the series history.
Zach Leonhardi paced the field to the green for the Papa John's Bandits feature. On lap three in the third turn, Joshua Hicks got a nose to the inside of Leonhardi to nab the top spot. Two laps later, Hicks made contact with Connor Younginer, giving the lead to Ashton Winger. Hicks worked his way up and on lap 13, used lapped traffic to pass Winger. Seven laps later, Hicks captured his first career Thursday Thunder trophy.
The Semi-Pro feature got underway with Jordan Coker as the leader. William Plemons III shot to the front on lap one and led every lap to seize the win.Josh Ballard kicked off the Buzz Cars feature as the point man. Alan Nolan in homage to the No. 10 Nesquik paint scheme got up to the front quickly. Debris on lap six brought out the caution flag, bunching up the field. Michael Karp muscled his way to the lead on lap eight. Dave Sherman and Karp swapped the lead back and forth for the remaining laps and on the last lap, Sherman drove it in deep for the lead, but ended up making contact with Buddy Brewer and
|
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] |
. Gibson and Wallace stunk, as did Nua and Herron. Kemoeatu in the 6th round was decent.
Not much needs to be said about Holmes. He’s a stud. Smith is still developing, but the coaching staff did sour on him some last season. Reid was drafted primarily for his special teams ability, which he magically lost upon arriving in Pittsburgh. Colon was pretty bad at right tackle, but I think he would do much better at left or right guard. None of the last five picks are even on the roster. That’s right. This draft was only two years ago, and yet five of our six picks on the second day are not on the roster today. Not acceptable.
It’s up to Colbert and Tomlin to improve between rounds 2-7. As I mentioned, last year’s draft looks like it could be a good one if Timmons ultimately fulfills his potential. But the failures in the previous ones are the reason why the Steelers are where they’re at today. It’s an aging roster that could cause the team to go downhill quickly if they don’t start drafting better after the first round. This is a draft that they need to hit big on, and they have to do it with only six picks since they traded away their 7th rounder for Allen Rossum. I think they need to get at least three eventual starters, and two decent depth guys. Obviously, we won’t know if that’s the case for at least a couple of years, but if in that time the 2008 draft looks similar to the ones in 2003-2006, well, we could be in trouble.
As a side note, I will be putting up a post on Friday detailing who I think the Steelers will ultimately pick in the 1st round. Most years I have a pretty good idea where they’re going, but this year, I could envision them going pretty much anywhere except quarterback and tight end. And on Saturday, sometime before the draft begins at 3 PM, I will post my final first round projection (along with Mel Kiper’s), and we’ll see if I can truly take down the man himself.
Well, the bad news is that the Steelers have shown interest in King. Tomlin and Colbert went to PSU's Pro Day to see him. He'd probably be a target in the 2nd round, but like you, I want no parts of him.
Even worse news is that they've shown an interest in Anthony Morelli. I'm hoping that's just to try and sign him to an undrafted free agent contract. If they spend a pick on him, I will punch my TV.
Cowher's talent-evaluation abilities don't look so good in retrospect, do they? Not to mention that Cowher didn't even want to select Roethlisberger. Cowher wanted to take Shawn Andrews, the fat guard from Arkansas who eventually went to the Eagles. Dan Rooney over-ruled him.
Yeah, I do remember the whole Andrews-Roethlisberger debate. Andrews is a very good guard, maybe one of the best in the league, but I think we can all be thankful that Rooney won out in that decision.
It was quite clear Cowher had a lot of influence over the draft. That's not to say that Colbert isn't at fault as well, but it may not be a coincidence that last year's draft was the first without Cowher and seems to be more well-rounded. I don't think Cowher's strong suit was player evaluation.
As long as they didn't waste a draft pick on him, I would like to see Morelli in camp, simply for the comic value. Guaranteed you would see at at least a few articles from the PG on his "arm strength that has the Steelers intrigued."
Assuming he never saw any real minutes, he'd be good to have around. The confidence he would give our DBs might prove to be invaluable.
Contributors
Who We Are
We're four guys who all love Pittsburgh and Pittsburgh sports. Stick around and you'll be sure to see humorous and occasionally well written posts about our favorite teams who don the black and gold. Still not sold? Then read our first post which pretty much sums everything up. Send all questions and comments to doubtaboutit@gmail.com. Your comments, critiques, and tips are what drive this site.Large Shackles Prop Set
Style #F59755
$11.97
Rattle your chains and muster up some horror with our Large Shackles Prop Set. This metallic colored prop features four shackles attached to a long linked chain. Use one to decorate a dungeon themed Halloween setting or improve your serial murdered costume.Introduction {#S1}
============
Unconventional T cells do not recognize classical peptide-Major Histocompatibility Complex (pMHC) ligands and can express αβ or γδ T cell receptors (TCRs). The ligands recognized by many unconventional T cells remain unknown. Established unconventional T cell ligands include lipid antigens presented by the conserved CD1 family of molecules, as recognized by Natural Killer T (NKT) cells and Germline-Encoded Mycolyl-lipid reactive T (GEM) cells. The human Vγ9Vδ2 T cell subset recognizes phosphorylated isoprenoid intermediates of lipid biosynthesis in the context of Butyrophilin 3A1^[@R1]^. The concept of T cell sensing of intracellular biosynthetic pathways was recently extended by the discovery that MAIT cells sense microbial metabolites bound to the evolutionarily-conserved, monomorphic MHC-class 1 related protein (MR1)^[@R2],[@R3]^. MAIT cell stimulatory antigens have been defined as riboflavin-derived derivatives produced by a range of bacteria and fungi^[@R4]^, notably 5-(2-oxopropylideneamino)-6-*D*-ribitylaminouracil (5-OP-RU)^[@R5]^. MAITs can rapidly clear pathogens through secretion of a range of cytokines that can be accompanied by granzyme and perforin expression upon recognition of these antigens bound to MR1^[@R6]^. MAITs are defined by their semi-invariant TCR gene segment usage consisting of TRAV1-2 rearranged with TRAJ33, 12 or 20, paired with a limited repertoire of TCR-β chains^[@R4],[@R7],[@R8]^, including but not limited to TRBV6 and TRBV20. More recent evidence shows that recognition of MR1-associated ligands can be accomplished by a wider range of TCR rearrangements including those using TRAV14, TRAV21 and TRAV36 chains and that MR1 can present a broader range of ligands than those from the riboflavin biosynthetic pathway, incorporating diverse chemical scaffolds which includes drugs and drug-like molecules^[@R9]--[@R13]^. In combination, these data suggest that MR1 presents a wide range of metabolic intermediates at the cell surface in much the same way as MHC molecules present arrays of peptides, and the CD1 family of molecules present various lipid antigens. T cell targeting of diseases via MHC Ib and MHC-I like molecules such as CD1 and MR1 is especially attractive as, unlike the highly polymorphic human leukocyte antigen (HLA) targets of conventional T cells, these molecules are largely monomorphic in the human population. Indeed, MR1 is ubiquitously expressed and the currently known non-peptide ligands it presents cannot mutate as they are essential biosynthetic intermediates to many microbes^[@R14]^. While most studies have indicated MR1 is only expressed on the cell surface after an MR1-binding ligand has bound^[@R14],[@R15]^ there is evidence that there is a basal surface expression, including on cancer cells^[@R9],[@R16]^. Intratumoural unconventional T cell infiltrations have also been associated with favorable prognostic outcome^[@R17]^, with MAIT cells also shown to have a role in multiple myeloma^[@R18]^. Human MR1 has a very limited number of silent and intronic polymorphisms^[@R19],[@R20]^ and natural isoforms^[@R21]^, highlighting its potential as a pan-population target. Currently, there are no self-ligands identified that bind to MR1 that induce a T cell response. However, there is increasing evidence that populations of MR1-restricted cells exist that likely respond to self-antigens^[@R9],[@R16]^. These MR1-restricted T cells are not classical MAIT cells in that they do not appear to possess a TRAV1-2 TCR nor do they react to bacterial antigens bound to MR1. Here we report of a novel non-MAIT TCR that recognizes a non-bacterial antigen restricted by MR1 resulting in lysis of cancer cells. This TCR does not respond to healthy cells but confers HLA-independent recognition to a wide range of cancer cells.
Results {#S2}
=======
Clone MC.7.G5 kills a broad range of cancer cells regardless of HLA allomorph {#S3}
-----------------------------------------------------------------------------
A T cell population that proliferated in response A549 cancer cells was grown from the peripheral blood mononuclear cells from an HLA-mismatched healthy donor ([Fig. 1a](#F1){ref-type="fig"}). Recognition of A549 cells by the αβTCR^+^ γδTCR^neg^ CD8α^+^CD8β^low^CD4^neg^ ([Supplementary Fig. 1a](#SD1){ref-type="supplementary-material"}) T cell clone MC.7.G5 grown from this line was not reduced by blocking MHC antibodies ([Fig. 1b](#F1){ref-type="fig"}). TCR sequencing of MC.7.G5 confirmed expression of an αβTCR; comprised of a TRAV
|
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] |
't do home pages the way other browsers do; you can save the URL as the startup page by going into settings and selecting "Save view profile 'web browsing'"
<p_quarles> gps23: because it has krunner, which is better
<jazman> just d/load fire fox or galeon browerser
<gps23> p_quarles, but in the name of freedom there should be an option to switch to katapult
<gps23> p_quarles, its not even in repos
<p_quarles> gps23: yeah, you're free to compile it
<JediatNight> Can anyone suggest a 3d game for ubuntu?
<gps23> p_quarles, thats ok, i can
<p_quarles> gps23: katapult is an app for KDE3 -- Kubuntu 8.10 doesn't use KDE3
<gps23> p_quarles, hmm, i got, i should myself used to krunner now
<Guest14877> p_quarles: settings or system settings?
<gps23> :(
<gps23> one more thing, i am unable to set shortcuts in my new kubuntu
<OxDeadC0de> well nightly is kind of nice, but doesn't have ruby bindings and there's an issue with the lancelot menu resizing.. hmm
<gps23> assigned a shortcut to konsole using menueditor, but its not working
<peter_> god morning from DK
<peter_> someone know how to connect a vista drive
<jazman> does it auot here the drive
<peter_> sorry i am new here idont know ist some mot??
<p_quarles> Guest14877: settings in Konqueror
<peter_> i see the harddisk but cant not see the files
<aleprof> hello, there is someone running vmware? I'm in troubles after update to 2.6.22.16 kernel version
<Guest14877> p_quarles: still trying to get it says malformed url
<Guest14877> p_quarles: what do i do just rename the one that says web browsing?
<Guest14877> how do i watch you tube videos on kubuntu?
<Guest14877> p_quarles: thnx for your help got it to work
<Guest14877> anyone know how to watch youtube vids on kubuntu?
<peter_> how can i see the files in a ntfs disk
<kamal`> hello kubuntu! :)
* kamal` is using Intrepid Ibex with KDE 4.1.2
<kamal`> i am just trying to find a way to assign shortcuts to launch apps in KDE 4.. no go so far :(
<kamal`> can someone here please be kind to help with it? :)
<kamal`> i had those set up in KDE 3.5.x earlier
<White_Pelican> in 4.2 beta 2 for Intrepid, I seem to have lost my icon that says there are software updates available. How do I get that back?
<kamal`> probably you gotta wait till more updates are available and it might pop up again :P
<White_Pelican> I think I accidentally clicked it and said remove
<missanthropic> okay i am about to sounds really stupid
<missanthropic> what do i use this for?
<missanthropic> i never used this IRC before
<OxDeadC0de> you talk with people, ask questions, help people, get help
<missanthropic> okay thats kinda what i was thinking
<missanthropic> so if i have any problems with my ubuntu or anything i can get information from people using the same system
<missanthropic> a lot easier than trying to find something online
<OxDeadC0de> ya but google will still be your #1 friend
<OxDeadC0de> this is #2
<missanthropic> heh. right
<missanthropic> always
<missanthropic> okay cool
<missanthropic> i am very new to this
<missanthropic> i love ubuntu
<gps23> how can i set shortcuts in kubuntu?
<gps23> using kde4
<OxDeadC0de> ok then, some useful info, please don't spam, use!pastebin for large posts, #kubuntu-offtopic for offtopic,
<OxDeadC0de>!pastebin
<ubottu> pastebin is a service to post large texts so you don't flood the channel. The Ubuntu pastebin is at http://paste.ubuntu.com (be sure to give the URL of your paste - see also the #kubuntu channel topic)
<missanthropic> ok
<OxDeadC0de> gps23 what do you mean shortcuts, in a folder view or in the menu? if in the menu, right click, menu editor
<OxDeadC0de> in a folder, make a link, you can probably do it through dolphin, if not, ln -s /path/to/real/file /path/to/where/I/want/it
<gps23> OxDeadC0de, in the menu, i wanted to define a shortcut for konsole, i used menu edit to set it, but its not working
<OxDeadC0de> gps123 I'm trying to test.. what version are you using? straight off the iso no upgrades? 4.1.3? 4.2beta2?
<gps23> its 4.1.2
<OxDeadC0de> gps23: you clicked "new item" set the name to konsole, then the command to konsole, then clicked save right?
<gps23> i tell u what i did, in menu edit, i went to utilities->konsole, there in second tab i set a shortcut for it, then i saved menuedit
<gps23> but its not working
<gps23> OxDeadC0de, sorry, its system->konsole
<OxDeadC0de> gps23 and what's it say when you click the new item in the menu, is it even there?
<gps23> OxDeadC0de, i didn't tried new item, because entry for konsole is already in system submenu
<OxDeadC0de> gps23 and when you go to system and click on konsole what happens?
<gps23> OxDeadC0de, then on right side, there are two tabs General, and advanced
<gps23> OxDeadC0de, in the advanced tab, there is a place to set shrotcut, labelled 'Current Shortcut Key'
<OxDeadC0de> gpss23 I can't test right now, I'm saving a menuitem,.. when I clicked save it went to 100% once slowly, then reset to 0 and did it again, then again, now it's on it's 4th run... wth
<missanthropic> ok thanks all bye
<gps23> OxDeadC0de, no, don't do new menu item, we don't want two konsoles in the menu
<OxDeadC0de> I'll undo it when I can, but it's saving.. been saving for 5 minutes..
<gps23> OxDeadC0de, kill menuedit
<OxDeadC0de> clicking cancel was easier.. hah. ok
<gps23> OxDeadC0de, trying new menu item
<OxDeadC0de> sry
<gps23> OxDeadC0de, i too added new menu item for test, its working fine here
<gps23> now, try to assign shortcut to already existing konsole entry
<gps23> OxDeadC0de, konsole is under system submenu
<OxDeadC0de> oh ok, I see now sorry took me a minute
<OxDeadC0de> works for me
<OxDeadC0de> but I'm in 4.2b2
<gps23> OxDeadC0de, setting shortcut is fine, but its invoking the shortcut which is not working
<OxDeadC0de> gps23 I see what you're saying, but I can't help, it works for me, but I'm using a newer version of kde
<gps23> OxDeadC0de, no probs, thanks for help
<furio> hola alguien tiene problemas con el netbeans 6.5 en ubuntu, a mi no me van los {} []
<hyper_ch>!es | furio
<ubottu> furio: En la mayorÃa de canales Ubuntu se comunica en inglés. Para ayuda en Español, por favor entre en los canales #ubuntu-es o #kubuntu-es.
<furio> I have problems with the netbeans 6.5, I try to write {} or [] and its impossible but my keyboard outside of netbeans works good.
<grassbaecker> hello everyone
<grassbaecker>
|
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final few weeks of uni, do my last exam, and hopefully just beach it a whole lot with my friends. I went to my friend Sarah's 21st on Saturday, got to see everyone (or mostly everyone. Ill have to visit Andrea sometime soon :D) and it was nice just hanging out with everyone, which is such a change from what I have normally been doing as of late.
So yeah, I'm hoping that I'm going to see my friends a whole lot more, and I aim to just have a lot of fun and take as many pictures as I can possibly take. It's not all the time that you have a four month summer holiday, so I may as well take advantage of it.
But before that I do have a few things to wrap up with Uni, of course, but I kind of love that rush of enthusiasm I get when I realise that I only have such a short time left to be studying. I always seem to pick up a whole lot more at the end of terms, it's just the way I work, I suppose.
Tuesday, October 19, 2010
With this being my 95th post, I'm thinking of doing something pretty darn special for number 100, but I haven't really decided on what I want to do yet. I'm sure something will come to me and it'll be pretty splendiferous.
Today was a pretty nifty day, I think someone has finally declared that it is shorts and thongs weather, which is kind of great. Thongs are entirely much more preferable to closed in shoes in the summertime, it can just be a bit of a bitch when it rains all of a sudden and the pattern on the thongs start rubbing off onto your feet. yuck.
And what's even better is that there is only three and a half weeks left of uni until the semester is over for the year, which makes me really excited :D I just hope that I have enough to do with people over the holidays, for some reason, (and I don't really know why, seeing as most of the people I know drive these days,) social gatherings have kind of been a bit sparce this year, a far cry from last year. But as I've been told, it's just different.
But I definitely think I can convince a few people to head off to the beach or something like that. :D
I think for the next post, I might put up another of my work music playlists, it seems like that was pretty popular, so stay posted folks.
Sunday, October 17, 2010
Last week was a particularly stress filled week, I had two essays amounting to about 4000 words, both due on Friday, and I thought that I had left enough time to get them well and truly finished in time for the deadline, but unfortunately that wasn't the case.
Needless to say, my Thursday and Friday were pretty hectic, but I am glad to say that I have effectively finished the two essays, and I have entered another unusual period where I don't really have to do a whole lot of stuff for university, and the stuff that I do have to do I'm pretty keen to get done, seeing as there is only about 4 weeks of studying left for the rest of the year!
Which is definitely exciting, however I just was not able to get to the blogosphere during last week, although I have been trying really hard to keep up with it as much as I can.
Either way, I've been able to take the time to read anothe Kathy Reichs novel which has really gripped me for the past couple of days, and my only gripe with her novels is that they are SO GOOD that I am not really able to stop reading them, which really compacts the enjoyment time I get from reading them. But nevermind, that is something that I choose to do when I read the books.
For the rest of the weekend, all has been pretty normal, I got a fair bit of sweater knitted this afternoon, and I should be able to get a photo on here soon, it is getting to a fairly decent size. I wrote a new blogpost in Swedish, just trying to get a few of them up. If anyone is able to help me out, rather than starting up a whole new blog, would I be able to make a page off my original blog page here, and post to that one seperately, rather than having alternating English and Swedish blog posts and just confusing everybody. If i can't, I'll just suck it up and make a new Swedish blogg.
Tuesday, October 12, 2010
By typing the words 'Dungeons and Dragons' into my google search bar, and then quickly quickly regretted it.
I just typed it in to see if I could find a world competition, or something like that. You know how there is the grand masters in Chess (or so I am guessing), i just would have figured there would have been an equivalent for Dungeons and Dragons.
But as soon as I typed in the words, my computer screen was filled with images of trolls, wizards, nifty magic spells you can use and stuff like that. A WHOLE lot of forums on the subject, and just generally a bit too overwhelming for my liking.
To bo honest, people kind of think that I am a pretty hardcore gamer, or for some reason or another they just think that I would seem to know about trolls and dark wizards and all the other connotated mystical creatures that come with RolePlayer Games, but to be honest, I would be the last person on earth to talk to if you wanted me to join in on one of your quests (or whatever them kids are calling it these days). It just never enticed me, I mean, I do like the Tony Hawks games on the playstation, as much as any other person would, but all of this WoW stuff, where you see kids glued to their computer screens for ridiculous periods of time, it never really got to me. And I'm kind of happy about it, the last thing that I need is for some more nerd factor to come out, I've got enough of that already.
Either way, if you might be interested in entering the world of Dungeons and Dragons, you can visit the official website here. But don't say that I haven't warned you.
Sunday, October 10, 2010
And I feel oddly calm with the week coming up, having two essays due on the same day. I'm unusually well prepared, which I'm extremely happy about, normally I wouldn't start an essay till about 2 days before it's due or so, but actually giving myself a whole week is simply astounding.
And actually, it has been kind of interesting researching for this English essay, the only difficult thing is picking which one I am actually going to write about, because so much of the information could overlap for so many of the questions.
Either way, things are looking pretty good at the moment, I only have about 5 weeks of university left, I'm getting more work for the time being, and there is not a whole lot left to do with university and I'll finally be finished for the year.
In the meantime, I've begun working on a better body for summer, which hopefully will work out, because it would be good to lose a bit of weight, especially with everyone at uni seeming to be in such good condition. I don't know if my perceptions are actually true, but in general it seems to be a very healthy, fit, and also really TALL student body at uni. I cannot get over the fact of how short I am in comparison to most of the other guys there which is kind of offputting. I kind of find getting to know and making friends with really tall people is just quite intimidating to be honest, simply because of the height difference. But that is just another one of my little quirks. I dunno.
Just thought I should do another little post, just to keep up the impetus :D
Saturday, October 9, 2010
Check out this.
If there was one thing that I was going to see this year, it would be Hot Water Music with the Bouncing Souls♥
Meanwhile, it's been a pretty miserable day, weatherwise, but excellent for working on my sweater, which is making slow but steady progress. I'll do a little bit of essay research tonight, get some main points written down, and then it really starts on monday. But hopefully I get to finish my essays on the thursday, because there is nothing that I hate more than having to drive all the way to university on Friday just in order to hand in my essay, and then just go back home again.
But I do like having essays and stuff to do at the moment, it kind of gives me a little bit of a sense of direction, just to do things, and it puts some sort of routine into life, which is always good, because without my routine I was getting a little bit lazy in the holidays.
Either way, I'm pretty spiffed that I have finally broken the 90 barrier, in terms of blog posts, I can't believe that I have written so many and kept up so well, and although there have been a few times where I have neglected my blog a little bit, I'm really happy with the way that I'm keeping up with it these days, I just seem to have a lot more time for blogging, and it's something that I actually want to do now, not just something that I feel that I have to do after I started it.
Eitherway, I'm baking a bread and butter pudding tonight, which hopefully will turn out
|
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of its ingredients anywhere online. However, you do not need to act like that; the reason is that the ingredients present in it are all-natural and effective. The ingredients have remained secret because the manufacturer did not want to create any issue with the copyright.
Normally, the ingredients are collagen boosting agents, skin firming peptides, and many others. Hydrolyzed Collagen is the main and active ingredient in this formula, which is used to restore enhanced amounts of collagen and other skin proteins in the skin. So, stay stress-free when it comes to considering the safety and efficacy of different ingredients used in the formula.
How does Nayvi Serum work?
The main thing to get familiar with is that how the product actually works so that you can be assured that it will definitely produce genuine results on the skin. So, understand the functioning of this product properly so that you can get started with it confidently. It is all about boosting the collagen cells in the skin with the help of the Hydrolyzed Collagen, which is the major ingredient. These cells are used by the body to restore broken, cracked or damaged skin. When you see your skin around the eyes, as well as the face, becomes dry and saggy, it is the time when the need of producing more collagen is important. With the enhanced collagen strands, it allows the skin to stay flexible in these areas.
When these cells are enhanced in the skin, your face will look hydrated, flexible and soft for years to come. As a whole, this skin care serum gives the younger look to your face without experiencing any kind of injection pain, or laser risk. So, what are you waiting for? Give this serum a try so that you can also get support to hide your wrinkles or other aging signs under the skin and never make them come on the surface of the skin.
Is Nayvi Serum safe to apply?
Yes, completely, due to high-quality ingredients, this product has taken a tag of the safe and top grade anti-aging solution than others on the market. It does not have any harsh effects on the skin.
How to apply Nayvi Serum?
This serum should be applied as mentioned on the label. Read the printed label carefully so that you can come to know its directions to use. It is a wise idea to wash your face prior to its application as the more chances; your face has dust or dirt particles to be deposited on the face. So, it is important to wash away them so that the skin surface can become clear to absorb all of the ingredients into it. Take care of the recommended application of this serum when you are going to apply it. It is suitable for every skin type and tone.
Is Nayvi Serum a recommended formula to apply?
Yes, this cream has obtained the recommendations from many experts of the skin care industry in different parts of the world. It is recommended to eliminate wrinkles as well as low hydration from the areas of your face, by skin care experts.
At what age you should apply Nayvi Serum?
When you are in a mature age, like 30 years or above, this anti-aging serum acts as the best option to consider. There are several conditions, in which you are not allowed to use this clinically proven anti-wrinkle serum, like if you are pregnant or nursing a baby, or using any other skin care formula, or many others. It should be preceded individually if you are interested in getting accurate and potential changes in the surface of the skin.When Bakul Dholakia was a young man, he says being a teacher meant something. The former dean of the elite Indian Institute of Management-Ahmedabad says the respect that students then had for teachers rivals that which they now have for star cricketer Sachin
Tendulkar.
Whether teachers and professors were so venerated can be debated, but there is no doubt the profession has fallen several notches on the list of students’ preferred careers.
In a country where wealth matters more than most – if only because of its extreme shortage – being a teacher once meant making a decent living. However, as salaries for corporates ector jobs have soared and those for professors have stagnated, the respect afforded to academics – and the subsequent desire of students to become them – seems to have done the same. A government panel said recently that India’s shortage of faculty staff could be “significantly higher” than the 40 per cent widely estimated.
While the prestigious Indian Institutes of Management and Indian Institutes of Technology – which cater to less than 40,000 of India’s roughly 16m college students – are largely immune to the overall shortage, even they have come under fire for lacking top-quality professors.
“There is hardly any worthwhile research from our IITs. The faculty in the IIT is not world-class. It is the students in IITs who are world-class,” Jairam Ramesh, a cabinet minister and IIT alumnus told reporters last year.
Elite institutions in ‘no need of top teachers’ The heads of the IITs and IIMs and others stress the need for more funding for fundamental research that will attract top-tier professors so that Indian schools are able to compete on a global level. But according to Karan Khemka, Asia head of the Parthenon Group, a US consulting group, the needs of those elite institutions are
at best overstated and in general irrelevant to the broader picture of Indian higher education. “The reason why [such institutions] can even float to where they are is the natural selectivity in India... if
you can afford to select from the top 0.1 per cent of your applicant pool, you are probably going to get kids who are so motivated and so brilliant that you could not teach them [at all] for three years and they’ll still come out pretty darn good,” he says. There is little point in viewing the IIMs or IITs as high quality, he says. It is the students who are high calibre. Consequently, says Mr Khemka, with such students these institutions have no need for world-class professors. That being the case, he adds, such institutions should continue to produce world-class students, but not research. “Can you name for me a piece of fundamental research that has come out of the IITs? So let’s not talk about fundamental research at all – in fact, [in] a country like India which has one-half of the world’s malnutritioned children, one-third of the world’s poor, should we even really be thinking about fundamental research?” As far as the rest of the higher education system is concerned, he believes, in a country where an estimated 84m young people are not in college, India needs to focus on its basic higher-level education.
The IITs and IIMs, he said, were excellent because of the quality of students.
The shortage of faculty staff has been further exacerbated because of
a government pledge to double the enrolment in India’s higher education system by 2020, to help meet the needs of its growing population. A lack of overall funding for the system has also meant that India has been unable to develop the sorts of world-class universities – and the incumbent fundamental research – that attracts top staff. Lower salaries and lack of research have made the shortage all the worse. How the country resolves these dual problems of the shortage of faculty staff and the dearth of world-class universities will determine whether it can realise the potential of its massive population.
The shortfall in faculty staff has its roots in the economic liberalisation of 1991. Since then, private sector salaries have increased from twice an academic’s $30,000 to sometimes more than 10 times that figure. By contrast, the average full-time business school nine-month salary in the US was $111,084 during the 2009-2010 school year, according to AACSB, the US accrediting body.
Prof Dholakia’s concerns are supported by a report this March from the Ministry of Human Resource Development’s taskforce on Faculty Shortage and Design of Performance Appraisal System, which reads: “Academic careers are unattractive when compared with the other professions. Not only are academic salaries uncompetitive, there are additional constraints to attracting the best talent... the social status of a teacher is not as high as it used to be in earlier decades.”
As more students desire MBAs (or engineering degrees) because of the lucrative remuneration, fewer will pursue PhDs and an academic career. Those that do invariably join the private sector or go overseas to teach, leaving fewer students with the necessary qualifications to teach in India.
Solutions for public sector schools especially, according to academics, come in a few broad categories: increase fees to boost staff salaries; upgrade decrepit facilities to attract researchers; and remove constraints on academic freedom.
The first is a fiscal issue that has been solved at the elite IIMs – where fees have more than trebled in the past five years, to about $30,000 for a two-year programme. That money – and their own prestige – has allowed universities such as IIM-Bangalore to escape the faculty-staff shortages, says the Trilochan Sastry, its dean.
“The universities are not paying well enough... [but] more than that, it is the way that things are governed: academics value freedom and some flexibility. Very often some of the systems tend to be very rule-bound and rigid,” he says.
IIMs tend to have more freedom, he adds. IIM-Bangalore produces 25 doctoral students each year, many of whom are going into
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] |
filters" => array:1 [▶]
"competition" => array:6 [▶]
"matches" => array:10 [▼
0 => array:12 [▼
"id" => 233107
"season" => array:4 [▶]
"utcDate" => "2018-10-20T11:30:00Z"
"status" => "SCHEDULED"
"matchday" => 9
"stage" => "REGULAR_SEASON"
"group" => "Regular Season"
"lastUpdated" => "2018-10-07T19:02:21Z"
"homeTeam" => array:2 [▼
"id" => 61
"name" => "Chelsea FC"
]
"awayTeam" => array:2 [▼
"id" => 66
"name" => "Manchester United FC"
]
"score" => array:6 [▶]
"referees" => []
]
1 => array:12 [▶]
2 => array:12 [▶]
3 => array:12 [▶]
4 => array:12 [▶]
5 => array:12 [▶]
6 => array:12 [▶]
7 => array:12 [▶]
8 => array:12 [▶]
9 => array:12 [▶]
]
]
I use Guzzle for doing this API request:
class GuzzleController extends Controller {
public function getMatches() {
$client = new Client();
$uri = 'http://api.football-data.org/v2/competitions/PL/matches/?matchday=9&season=2018&matches';
$header = ['headers' => ['X-Auth-Token' => 'My-Token']];
$res = $client->get($uri, $header);
$array = json_decode($res->getBody()->getContents(), true);
dd($array);
}
}
I created a model 'Match' and added a migration:
class Match extends Model {
// What code here?
}
The migration:
public function up() {
Schema::create('matches', function (Blueprint $table) {
$table->increments('id');
$table->timestamps();
$table->integer('match_id');
$table->string('homeTeam');
$table->string('awayTeam');
});
}
Any tips on how to store this data to my database on the match model?
A:
You can achieve this by getting all matches data and then looping through each one using a collection.
Collections can be created from array data using the collect() helper.
class GuzzleController extends Controller
{
public function getMatches()
{
$client = new Client();
$uri = 'http://api.football-data.org/v2/competitions/PL/matches/?matchday=9&season=2018&matches';
$header = ['headers' => ['X-Auth-Token' => 'My-Token']];
$res = $client->get($uri, $header);
$data = json_decode($res->getBody()->getContents(), true);
return $data['matches'];
}
public function saveMatches()
{
$matches = $this->getMatches();
collect($matches)
->each(function ($match, $key) {
Match::create([
'match_id' => $match['id'],
'homeTeam' => $match['homeTeam']['name'],
'awayTeam' => $match['awayTeam']['name']
]);
});
}
}
With this code, we call the saveMatches() function, which calls the getMatches() function (used to run the guzzle call).
Then, for each match, we save a new record to the database use the Match facade.
Notes
As mentioned above, it may be best to create a Team model, so you are able to identify and call matches based on teams.
Make sure to call the $fillable or $guarded class variable in your Match model to be able to store data (see here).
Update
To use this functionality in a job, you first need to create a job using
php artisan make:job <job name>
For example, the job could be called CreateMatches. This will be located in app/Jobs/CreateMatches.php.
There you will see a handle() function, which is used to call any functionality within it once the job has fired.
public function handle()
{
$this->saveMatches();
}
public function saveMatches()
{
// Code goes here
}
public function getMatches()
{
// Code goes here
}
You can then call the job, anywhere in your application logic using either CreateMatches::dispatch() or by using dispatch(new CreateMatches()) (don't forget to use the class at the top of your file).
Funny you say that because I find the anonymity of it to be the sexiest thing about it! I'm a worshipper, pussy primarily but cock too on occasion. My focus is that, just pure physical pleasure without the emotion
This clip with Charlotta... Please make this a reality. I think she would make a better connection to the guy and deliver this bdsm massage with lots of exotic smiles. Please keep the bondage and bdsm hand jobs coming, even though it's not everyone's cup of tea.
For me, this was very non-hegre like. The sensual, beautiful, artistic feel just wasn't there. It felt more like I was watching something of less quality, something just thrown together. Didn't like the man AT ALL, very un-sexy. The girl, well we never see her face so I have no idea. On top of that, it was very bland, very repetitive.. the last two massages have been heading in a direction that will probably leave me without a sub. Not pleasurable for me.
Yes I agree.
Couldn't connect with the sensuality of the watching, we need to see the reactions (faces). Love the bondage aspect, but would love the teasing aspect of bondage, pain and pleasure, also wasn't into the string but the rope was nice, blindfolds would be great, etc... was looking for something more.. just not a turn on for me... I know it's good if I watch it over and over and this I didn't even watch the whole thing.. just too predictable.
Hi,
I know that lot's of people like this but to me ths is the worst I've seen on hegre.......
The way he ejaculates is extremly intense anyway.
I would like to see more real massages in a cosy and warm bedroom or outdoor. I would like to see a girl squirting which is an outstanding experience since I have girl who can do this any time she wants.
hain
First, great video! This is the type of dynamic trend I like to see here on Hegre.com. Getting two "Massage" videos in a row is a nice departure from the norm thus far this year (although, I disagree that last weeks video should have even been counted as a "Massage" film when it clearly was not). This year has been dominated by mostly "Film" videos each Monday nigh, and I (and probably speaking for other fans of this website) prefer the Film-Massage-Film-Massage... weekly updates of yesteryear. To be honest, if I had my preference I would actually only prefer to see "Massage" video updates -- which is the reason I paid for the year-long membership to this site. I'd pay a whole lot more money to be a member of a "Massage" only version of this site. The rest of the site, to be honest, is usually fairly boring and being done elsewhere. The "Massage" videos are where Hegre sets itself apart!
The obvious excitement and physical attraction of the bodies I do like in this video. It would bring me much more pleasure without the anonymity of the models involved. The masseuse has a great body, surely her face and her expressions will bring additional attrractions
Agreed. The anonymity was by design of course, but the upside of expressions can't be beat. Petter is good at capturing the face and he's perfecting the art more each year. So the video is interesting and fun, but not a wowie! Footnote: She truly knows The Art of Cock Control. Ladies, take note. This is a hugely powerful skill. Notice how at the end she gets aggressive? Don't forget. I've seen a ton of Russian videos where the guy has to finish himself lol because she hasn't learned. Double lol
Light, playful BDSM can produce a very pleasureable stimulation, especially when one is brought repeatedly to the edge of orgasm and then denied release. The early pre-cum made one wonder if the submissive could last for
|
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] |
4012.50.47 (0.15-1.45)0.191Center C4022.51.24 (0.47-3.23)0.666SexMen8622.11Women348.80.33 (0.10-1.15)0.081Age (years)\<602821.410.27260-69429.50.34 (0.09-1.29)0.11370-794025.01.04 (0.35-3.06)0.949≥801020.01.06 (0.19-5.86)0.943StageII1428.610.573III9315.10.59 (0.18-1.88)0.372IV1233.31.30 (0.30-5.58)0.723Missing10.0(-)0.981[^6][^7]
Discussion {#s0035}
==========
This study brings to light the existence of considerable variability in clinical practice [@bb0035], [@bb0065] among three centers working with the same care protocols, demonstrating that consensus-based clinical practice guidelines and ISO certification are not enough; systematic monitoring and evaluation of each planned change are required to achieve the desired adherence.
For rectal cancer, the therapeutic strategy includes determining which patients are at the most risk, and high-resolution MRI is the most accurate technique, allowing us to identify the mesorectal fascia and its relation with the tumor front with a specificity of 92% [@bb0070]. The distance from the tumor to the mesorectal fascia (rCRM) is predictive of local recurrence. The results obtained for this indicator show considerable room for improvement: even though all the patients had an MRI, the medical records of 38.3% did not contain information on this parameter either in the diagnostic report or over the clinical course, making it a prime target for improvements. The relevance of this indicator has been recognized, for example, in the work of the Mercury Group [@bb0075], which reported that the rate of recurrence ranges from 53% in tumors with a potential margin of less than 1 mm of the CRM to 8% in patients with an rCRM of 8 mm or more.
In the treatment phase, adherence to clinical practice guidelines regarding the type of radiotherapy prescribed (LCRT versus SCRT) was rather low: 12 patients (10%) were indicated for SCRT, but 6 did not meet the pertinent criteria. Of the 9 patients who did meet the criteria for SCRT, only 6 (66.7%) received it. Although the indication of one technique over another has not been linked to local control, survival, late toxicity, or quality of life [@bb0080], the advantage of SCRT over LCRT lies in the simplicity of its administration and patients' reduced dependency on the hospital. Moreover, regarding adherence to the planned treatment, the results are not optimal either, especially in one center. We observed that 13% of the cases were prolonged more than 5 days over the initial plan. Numerous studies directly relate local control of the tumor with the prolongation of radiotherapy [@bb0085], [@bb0090], [@bb0095], [@bb0100]; Bese [@bb0105] found that for cancer of the head and neck, each day that treatment was interrupted led to a decrease in local control of 1.4%. There is less evidence for rectal cancer, but we consider that administration of radiotherapy should rigorously adhere to the treatment plan and that it is unacceptable to prolong it more than 5 days, especially when the main reasons are avoidable organizational factors. As described in the Royal College of Radiologist guidelines [@bb0110], which also apply here, most interruptions are due to public holidays that fall on weekdays and technical issues (machine inspections and breakdowns). These factors are generally known well in advance, and staff should take them into account when planning treatment. A range of options is available to compensate for the negative effect of these interruptions, but essentially, it is a question of developing and implementing a protocol tailored to each center's circumstances. Updating the protocol and regularly monitoring this indicator are actions that we use to improve adherence to planned radiotherapy treatment. Overall, the degree of adherence to clinical practice guidelines could be significantly better. We believe that a reasonable mechanism to improve it would be automated alerts and reminders---referring to consensus-based indicators---sent to professionals at the clinical station in order to support the decision-making process. This approach has led to improvements in other clinical settings [@bb0115], [@bb0120].
Finally, the other indicator considered crucial due to its prognostic value in patients' evolution is the result of the ypCRM [@bb0125]. We observed that only 4.3% of the patients had a positive postoperative ypCRM margin, compared to the 8% to 13% in other published reports [@bb0130], [@bb0135], suggesting good results. However, and as with the rCRM value, the ypCRM values for 34.5% of the patients who underwent surgery are unknown. While other studies have reported similar percentages [@bb0140], we have launched several actions for improvement. We believe that the tumor board sessions are invaluable, and in addition to using this time to reach a consensus on each patient's treatment plan, it should be used to emphasize the importance of everyone on the multidisciplinary team being able to access CRM data, which in this case implies that the anatomical pathology and diagnostic imaging services should add these data to their respective reports.
With regard to the clinical results, it is difficult to assess the adverse effects, in part because the design of the questionnaire did not allow any differentiation between acute and chronic events but mostly because the poor quality of the notes taken over the clinical course made grading the severity of the effects difficult. Without a doubt, adopting a registration system with structured data would produce more objective and internationally comparable data [@bb0145]. Furthermore, we confirmed the scant references to certain adverse effects, especially those related to the sexual sphere or sphincter control; the presence (or absence) of these effects should clearly be noted in the clinical histories. In fact, the questionnaire does not include any items related to quality of life, which we consider to be a limitation of the study to be rectified in future audits. There is no question that awareness among professionals should be raised with regard to monitoring patients' quality of life, and we believe that the use of a validated questionnaire in these patients could be useful for systematizing an essential dimension of clinical results [@bb0055], [@bb0150]. Other study limitations relate to the design of the audit itself, as the sample of just 40 medical histories limits our assessment of the results and the comparison between centers, particularly for indicators on clinical results. Moreover, the period analyzed, 2013, was chosen so that we could assess all phases of the process, including follow-up and 4-year survival; however, some results have changed considerably since then. As with any review of clinical histories, the data are derived from the information contained in clinical registries, and any considerations not recorded there are also absent from the audit.
In conclusion, the audit we performed revealed a suboptimal degree of adherence to clinical practice guidelines for rectal cancer. Significant variability between centers exists from a clinical perspective but especially with regard to organization and process. In that sense, the value of a clinical audit like the one performed resides in its power to shed light on the need for improvement in areas that may otherwise have been considered resolved. Additionally, the audit raises questions about how to improve adherence to guidelines, what value professional consensus confers, and how to translate that consensus to practice during patient care. Clearly, the approval of a document by a group of experts is insufficient. We believe that using information and communication technologies in the form of automated guidelines to aid professionals at the clinical station could be the way to improve adherence. In any case, measuring and evaluating performance through a clinical audit are the first steps for improving clinical processes for the benefit of our patients.
Funding {#s0040}
=======
No specific funding for this study.
We should like to thank all the professionals involved in the Radiotherapy process in the Institut Català d'Oncologia (Catalonia), without whom this study not have been possible.
[^1]: *EBRT*, external beam radiotherapy; *BQT*, brachytherapy.
[^2]: TNM Classification of Malignant Tumours (UICC) (Five edition, 1997)
[^3]: No data found in the medical records.
[^4]: *Chemo*, chemotherapy; *RT*, radiotherapy; *VMAT*, volumetric arc therapy; IMRT, intensity-modulated radiation therapy.
[^5]: No data found in the medical records.
[^6]: Dash (-) used when HR and 95% CI could not be calculated.
[^7]: Specification cox model (statistical). This model collect the mortality for 4 years adjusted by center, sex, age group and stage.
Q:
Symfony 2 doesn't generate web/bundle/framework structure
I have a huge problem with Symfony. I installed Symfony 2.7.5 from command line:
$ symfony new my_project
But the main problem is that all project was generated correctly with the exception of directory: /web/bundle
So I have in this folder two empty files (not catalogues!) with 0 KB size: framework and sensiodistribution. That means all Symfony error pages haven't any css style and look ugly.
Screens:
My local folder:
and
Error page:
What should I do?
A:
Command:
$ app/console assets:install
populated this catalogue and it was the solution of the problem.
|
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15
] |
I promise, I am nice. I'm really, really nice. We were looking for our cat— No, OK, just, look, just call this number. This is Roman Pelka, he's with the Met, he'll explain.'
'Roman isn't really with the Met,' I try to say, but it comes out, 'Glug gluh wah wah ooogh.'
'This is just a Spacetime address,' Kay scoffs. 'This could be anyone.'
'They're the Dream Police,' Shandy says. 'We're investigating your upstairs neighbour, the tall guy? Oh, how did you like the chocolate?'
'Chocolate?' George groans. 'That was from you? What kind of psycho are you? I accused my wife of having a fancy man when I saw that gift.'
Shandy breaks into a chortle, but Kay tugs on her husband's jacket sleeve.
'Oh, George, she's talking about that weird lad upstairs who talks to himself! They're investigating him!'
'No, I don't trust them. There's no such thing as the Dream Police.'
George stands across the doorway, brandishing a large umbrella. He's ninety if he's a day.
'You're right,' his wife says with a sigh. 'Listen, girls, just sit there and wait for the police. I will make tea. You can tell the real police whatever you want about the Dream Police. My husband and I need to know we can sleep safe at night.'
That's all any of us wants, isn't it?
'So how was the show?' Shandy asks, weakly.
* * *
We spend the rest of the night in Holborn Police Station because apparently there's a problem with the toilet at Kentish Town. It isn't as nice as I'd expected for the neighbourhood, plus they confiscate our headware until Donato arrives. I'd really been hoping for Roman, but such is my luck. Donato looks even more pissed off than usual. Shandy tries to flirt with him but it doesn't work. Maybe he's gay. Or maybe it's just because by that time of night her breath is lethal and her bubblegum has also been confiscated.
With that said, Donato talks to the police and the Shojis. Luckily the Shojis are really sweet, and somehow Donato makes it so Shandy and I are going to be let out. I'm not sure on the details because I sleep through most of it. When I awaken, I can recall several anxiety dreams, but I wasn't lucid in any of them and there was no sign of Bernard. I have a bad feeling about the whole thing, especially Daphne being in the middle of it. I'm in deeper waters than I thought.
Donato is uber-grumpy when we're finally released from the holding cell, which now has a pile of vomit and a drunk girl asleep on a bench. I don't realise it's 6 a.m. until I get my headware back. A big pile of messages are bursting to be read, but I ignore everything. I ping O straight away to let her know I'm all right, but then go dark because I don't want to have to speak to her right now. She's going to be cross.
'Sorry you got dragged out of bed,' I say to Donato as we walk down the silent road towards Holborn Station. And then, because I can't help my curiosity about where Roman is, I add, 'Was it your turn to babysit tonight?'
He looks at me keenly. I don't know what it is about Donato, but he makes me feel guilty even for things I haven't done.
'I sent Roman to talk to Bernard.'
'Oh, that can't be a good idea. Bernard has no idea we were there, and he's already mad because of the way Shandy's been stalking him.'
'I'm not stalking him!' Shandy protests. 'If I were stalking him, he'd never even know it until it was too late.'
'Do you stalk many people, then?' Donato asks.
I punch Shandy's arm. 'She doesn't. It's just a front, honestly.'
Donato gets a distracted expression on his face and there's a break in his stride; that's how I can tell he's in Spacetime, but it's a private convo. I can't see anything.
He stops in his tracks. Turns his back on us. Shandy offers me gum and I accept. Then I lean on her. I need to lie down.
'Not here. You can sleep on the Tube.'
I yawn. The edges of my vision are blurring and my gums ache. My head is full of static, like I'm receiving the cosmic microwave background in my fillings. Shandy steps on my foot, sharply.
'Owie.'
'Stay awake. Something's happening. I think he's going to call for his invisible plane in a minute.'
Donato turns around. He is furious.
'Well, isn't that interesting? Roman is in Bernard's flat as we speak. It took him two hours to bypass the security system, but he's in now.'
'Yeah, so?'
Now it's my turn to step on Shandy's foot. Belligerence won't get her anywhere with Donato, except maybe back in lock-up.
'Bernard isn't there. That'd be because he's dead. Roman just received a call from the Transport Police. Bernard walked in front of a train on the Northern Line. What have you got to say for yourself, Charlie?'
Nothing. I have nothing to say. Because I really need to sleep. Right now.
I hear people talking but I don't know where I am. I don't even know which way is up or what position my body is in. It's like I'm floating, and then I hear Shandy's voice.
'You both know Charlie didn't do this. She's being framed – can't you see that? I mean, look at her. She can't even— Look at her – she's like a child.'
'Or that could be just a cover,' Donato says. 'Have you noticed how she conveniently falls asleep whenever she's under pressure?'
'That's because she's sick!'
'Allegedly.'
'Don't be a cunt, Donato. Use your head. Charlotte doesn't understand the world. I've known her for years, she gets lost on her way from the toilet to the fridge, she's not capable of planning anything even if she had one single malicious bone in her body. Which she doesn't. So just stop it. No, I don't want coffee, I want you to leave her alone. She's one of the good ones and I won't— Hold on, this is O on that bloody archaic app she uses instead of Spacetime.'
I come swimming into awareness reluctantly. It's nicer in sleep. I seem to be doing the Grand Tour of sofas, because we are in Bernard's flat, and I'm trying to figure out how that even works. Surely the police should be here, and forensics, and we should be in jail if they really think I did this somehow – and judging from what Shandy is saying, they do.
'Charlie. Can you hear me. It's Roman.'
His voice is coming from somewhere near my head. It feels like everything is moving, like my senses can't figure out which of my body parts is where. I manage to make a sound.
'Can you move? Charlie, I'm a little concerned about you. If you are able to, try and make a sound again.'
It's so hard to force myself to do it. I just want to float and drift...
'Charlie? Come on. Stay with us. I know you don't want to end up in A and E. They'll stick needles into you and do things to wake you up, and it'll be very unpleasant. I'm touching your hand. Can you feel that?'
He's holding my hand. How sweet.
'Don't be so poncey, Roman.' Shandy's voice, her breath in my face, and now I'm starting to feel my body more. 'For fucksake, assert yourself. Oh, never mind, I'll do it.'
Then Shandy slaps me across the face and my eyelids fly open. She's giving me eyes as wide as an All-Blacks player doing the Haka and her spittle flies into my face with the force of her words.
'Hey! Guess what? Bernard's dead. Actually dead. How can you sleep through this? You're a suspect, but there aren't even any police. But there's a dog! He's so cute. Wake the fuck up!'
I'm on Bernard's sofa.
'There's a dog?' I say weakly. I love dogs.
'Nope, I lied. And that, Roman dear, is how it's done.'
I see her legs and arse receding as she crosses the room to continue her intense conversation with Donato, in which every other word she uses seems to be 'cunting'. Roman is still holding my hand.
'I have coffee for you.
|
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(TIF)
######
Click here for additional data file.
######
FcγRIIIA genotype and overall survival (OS) in the lenalidomide plus cetuximab combination therapy arm. There are no significant differences in OS among the three genotype groups for FcγRIIIA. The median OS is 176, 152, and 111 days for the "F/F", "F/V", and "V/V" groups, respectively.
(TIF)
######
Click here for additional data file.
######
Epidermal growth factor receptor (*EGFR*) copy number and overall survival (OS) in the lenalidomide plus cetuximab combination therapy arm. In the lenalidomide plus cetuximab combination therapy arm, OS was significantly shorter for *EGFR* FISH-negative than for *EGFR* FISH-positive subjects (median OS: 150 and \>336 days, respectively). One subject whose *EGFR* status was tested twice by Genoptix had a negative and a positive result, and was considered *EGFR* FISH-positive for this analysis.
(TIF)
######
Click here for additional data file.
######
Epidermal growth factor receptor (*EGFR*) copy number and overall survival (OS) in the lenalidomide monotherapy arm. In the lenalidomide monotherapy arm, OS was shorter for *EGFR* FISH-negative than for *EGFR* FISH-positive subjects (median OS: 86 and \>277 days, respectively).
(TIF)
######
Click here for additional data file.
######
CONSORT Checklist.
(DOC)
######
Click here for additional data file.
######
Trial Protocol.
(PDF)
######
Click here for additional data file.
[^1]: **Competing Interests:**Salvatore Siena is a member of advisory boards for Sanofi-Aventis, AstraZeneca, Roche, Genentech, and Amgen, and was supported by Oncologia Ca\' Granda Onlus (OCGO) Fondazione. Eric Van Cutsem has received research funding from Merck-Serono, Roche and Sanofi-Aventis. Andrea Sartore-Bianchi received lecture fees from Merck Serono and Roche, is a member of advisory board for Amgen, and was supported by Oncologia Ca\' Granda Onlus (OCGO) Fondazione. Josep Tabernero has participated in advisory boards for Amgen, Celgene, Genentech, Merck-Serono, Novartis, Roche, Sanofi-Aventis, and Symphogen. Katia Bencardino was supported by Oncologia Ca\' Granda Onlus (OCGO) Fondazione. Mingyu Li, Ulf Jungnelius, Alfredo Romano, Robert Beck, Anita Gandhi, and Tao Shi are Celgene employees and stockholders. This study was funded by Celgene Corporation. Cetuximab was provided by Merck KGaA. Medical writing services were provided by Kim Grootscholten, MSc, of Excerpta Medica BV, funded by Celgene Corporation. Mingyu Li, Ulf Jungnelius, Alfredo Romano, Robert Beck, Anita Gandhi and Tao Shi are employed by Celgene Coporation. The Lenalidomide (Revlimid®) used in this study is a Celgene Corporation product. There are no further patents, products in development or marketed products to declare. This does not alter the authors\' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
[^2]: Conceived and designed the experiments: SS EVC UJ JT. Analyzed the data: SS EVC ML UJ AR RB HP AG TS JT. Performed the trial/contributed patients: SS EVC KB MEE HP MS ASB ST JT. Wrote/contributed to the manuscript: SS EVC ML UJ AR RB KB MEE HP MS ASB ST AG TS JT.
Ephedra sinica inhibits complement activation and improves the motor functions after spinal cord injury in rats.
The activation of complement system has been known as an important and significant reaction against the secondary injury after spinal cord injury (SCI). In the present study, we investigated the effect of Ephedra sinica to the inflammation or complement system of injured spinal cord and the influence to the functional recovery after spinal cord injury in rats. We prepared the complement-inhibiting component from E. sinica. Contusive spinal cord injury was induced to Sprague-Dawley rats. We administrated the product from E. sinica to E. sinica group, while distilled water was administered to the control group by gavage after SCI. Complement hemolytic activity (CH50), expression of C3 and C9, myeloperoxidase activity, and motor function were evaluated in E. sinica group and control group. The CH50, complement depositions, and myeloperoxidase activity in the E. sinica group were significantly reduced as compared to the control group. The motor function of E. sinica group was significantly improved from the 7th day as compared with the control group. The results demonstrated that E. sinica might reduce inflammation and improve motor function in rats after spinal cord injury by inhibiting complement activation. The present study has shown that complement system is playing an important role in spinal cord injury, and the possibility of a new therapy strategy, inhibiting or controlling the complement activation and inflammation, for spinal cord injury.We use cookies to customise content for your subscription and for analytics.If you continue to browse Lexology, we will assume that you are happy to receive all our cookies. For further information please read our Cookie Policy.
Case update: protecting your interests from defamation actions
The case of Ell v Milne (No 5) [2013] NSWSC 246 reinforces the need for authors to separate opinion from fact when communicating with third parties.
Facts
This case arose out of an email sent by Councilor Katie Milne of the Tweed Shire Council. In the email, Ms Milne made several imputations about Mr William Ell, a local property developer including that:
he was implicated by his own wrongful conduct in the murder of Mr McGurk;
he had a scandalous association with a murdered man (Mr McGurk);
he paid $100,000 bail for a person who was suspected by police of serious crimes of violence in order to advance his business interests;
he paid bail for a person suspected of serious crimes because he approved of the use of violence in his business ventures;
he paid bail for services rendered by Mr McGurk as a standover man; and
he conducted his business with regard to property development by hiring a person with a reputation for violence.
Ms Milne sent the email, headed “letter to the editor”, to several newspapers and special interest groups.
Court’s Decision
The court found that imputations (b), (c) and (f) were conveyed in the manner complained of. Notably, her Honour defined a “scandalous association” (imputation (b)) as “one which causes scandal to the public”. The court held that the characterisation placed on Mr Ell’s association with Mr McGurk satisfied this definition.
However, the court was not satisfied that imputations (a), (d) and (e) were conveyed. Her Honour labeled the leap from allegations against Mr McGurk to the proposition that Mr Ell approved of the use of violence in his business ventures as “too strained”.
Practical Tips
This case highlights the need for both individuals and companies to implement adequate safeguards to protect themselves from potential defamation claims. Before content is published, authors must ensure that:
all information contained in the publication is true. A defence is available to publishers where a statement is substantially true;1
a second responsible individual has viewed the work prior to publication;
adequate records are maintained that substantiate content. This will also provide protection in the event that a defamation action is launched at a later date;
insurance has been purchased, particularly where content is being published on behalf of an organisation;
the place of residence of the subject of the story has been given consideration. For example, the subject of the article will usually have a reputation in the place where they are a resident. Further, each State and Territory have different defamation laws; and
the article does not breach any other laws such as contempt or copyright.
Finally, it should be noted that the author’s subjective intention (good or otherwise) is irrelevant when considering the meaning of words for the purpose of commencing an action.
To view all formatting for this article (eg, tables, footnotes), please access the original here.Music
One of Prof. Laughlin's hobbies is
musical composition. Click on the links to the left to obtain PDF
renderings of his original scores. The original ETF sources (written using
Finale 3.0) are available in the archive.
Prof. Laughlin is in the process of making good recordings of these
pieces, but at the moment has only time to produce raw MIDI files from the
scores.2011 Hyundai Elantra - Great economical car
Sean
El Paso, Texas
Overall
4.0
Value
4.0
Performance
3.0
Style
4.0
|
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] |
var accept = accepts(this);
return accept.languages.apply(accept, arguments);
};
/**
* Parse Range header field,
* capping to the given `size`.
*
* Unspecified ranges such as "0-" require
* knowledge of your resource length. In
* the case of a byte range this is of course
* the total number of bytes. If the Range
* header field is not given `null` is returned,
* `-1` when unsatisfiable, `-2` when syntactically invalid.
*
* NOTE: remember that ranges are inclusive, so
* for example "Range: users=0-3" should respond
* with 4 users when available, not 3.
*
* @param {Number} size
* @return {Array}
* @api public
*/
req.range = function(size){
var range = this.get('Range');
if (!range) return;
return parseRange(size, range);
};
/**
* Return the value of param `name` when present or `defaultValue`.
*
* - Checks route placeholders, ex: _/user/:id_
* - Checks body params, ex: id=12, {"id":12}
* - Checks query string params, ex:?id=12
*
* To utilize request bodies, `req.body`
* should be an object. This can be done by using
* the `bodyParser()` middleware.
*
* @param {String} name
* @param {Mixed} [defaultValue]
* @return {String}
* @api public
*/
req.param = function(name, defaultValue){
var params = this.params || {};
var body = this.body || {};
var query = this.query || {};
if (null!= params[name] && params.hasOwnProperty(name)) return params[name];
if (null!= body[name]) return body[name];
if (null!= query[name]) return query[name];
return defaultValue;
};
/**
* Check if the incoming request contains the "Content-Type"
* header field, and it contains the give mime `type`.
*
* Examples:
*
* // With Content-Type: text/html; charset=utf-8
* req.is('html');
* req.is('text/html');
* req.is('text/*');
* // => true
*
* // When Content-Type is application/json
* req.is('json');
* req.is('application/json');
* req.is('application/*');
* // => true
*
* req.is('html');
* // => false
*
* @param {String} type
* @return {Boolean}
* @api public
*/
req.is = function(types){
if (!Array.isArray(types)) types = [].slice.call(arguments);
return typeis(this, types);
};
/**
* Return the protocol string "http" or "https"
* when requested with TLS. When the "trust proxy"
* setting is enabled the "X-Forwarded-Proto" header
* field will be trusted. If you're running behind
* a reverse proxy that supplies https for you this
* may be enabled.
*
* @return {String}
* @api public
*/
req.__defineGetter__('protocol', function(){
var trustProxy = this.app.get('trust proxy');
if (this.connection.encrypted) return 'https';
if (!trustProxy) return 'http';
var proto = this.get('X-Forwarded-Proto') || 'http';
return proto.split(/\s*,\s*/)[0];
});
/**
* Short-hand for:
*
* req.protocol == 'https'
*
* @return {Boolean}
* @api public
*/
req.__defineGetter__('secure', function(){
return 'https' == this.protocol;
});
/**
* Return the remote address, or when
* "trust proxy" is `true` return
* the upstream addr.
*
* @return {String}
* @api public
*/
req.__defineGetter__('ip', function(){
return this.ips[0] || this.connection.remoteAddress;
});
/**
* When "trust proxy" is `true`, parse
* the "X-Forwarded-For" ip address list.
*
* For example if the value were "client, proxy1, proxy2"
* you would receive the array `["client", "proxy1", "proxy2"]`
* where "proxy2" is the furthest down-stream.
*
* @return {Array}
* @api public
*/
req.__defineGetter__('ips', function(){
var trustProxy = this.app.get('trust proxy');
var val = this.get('X-Forwarded-For');
return trustProxy && val
? val.split(/ *, */)
: [];
});
/**
* Return subdomains as an array.
*
* Subdomains are the dot-separated parts of the host before the main domain of
* the app. By default, the domain of the app is assumed to be the last two
* parts of the host. This can be changed by setting "subdomain offset".
*
* For example, if the domain is "tobi.ferrets.example.com":
* If "subdomain offset" is not set, req.subdomains is `["ferrets", "tobi"]`.
* If "subdomain offset" is 3, req.subdomains is `["tobi"]`.
*
* @return {Array}
* @api public
*/
req.__defineGetter__('subdomains', function(){
var offset = this.app.get('subdomain offset');
return (this.host || '')
.split('.')
.reverse()
.slice(offset);
});
/**
* Short-hand for `url.parse(req.url).pathname`.
*
* @return {String}
* @api public
*/
req.__defineGetter__('path', function(){
return parse(this).pathname;
});
/**
* Parse the "Host" header field hostname.
*
* @return {String}
* @api public
*/
req.__defineGetter__('host', function(){
var trustProxy = this.app.get('trust proxy');
var host = trustProxy && this.get('X-Forwarded-Host');
host = host || this.get('Host');
if (!host) return;
return host.split(':')[0];
});
/**
* Check if the request is fresh, aka
* Last-Modified and/or the ETag
* still match.
*
* @return {Boolean}
* @api public
*/
req.__defineGetter__('fresh', function(){
var method = this.method;
var s = this.res.statusCode;
// GET or HEAD for weak freshness validation only
if ('GET'!= method && 'HEAD'!= method) return false;
// 2xx or 304 as per rfc2616 14.26
if ((s >= 200 && s < 300) || 304 == s) {
return fresh(this.headers, this.res._headers);
}
return false;
});
/**
* Check if the request is stale, aka
* "Last-Modified" and / or the "ETag" for the
* resource has changed.
*
* @return {Boolean}
* @api public
*/
req.__defineGetter__('stale', function(){
return!this.fresh;
});
/**
* Check if the request was an _XMLHttpRequest_.
*
* @return {Boolean}
* @api public
*/
req.__defineGetter__('xhr', function(){
var val = this.get('X-Requested-With') || '';
return 'xmlhttprequest' == val.toLowerCase();
});
Q:
How do you survive the plague?
In The Guild 2, how on earth do I survive the plague?
As soon as it hits town, All my family members seem to get it. Before I know it, my entire dynasty has been wiped out.
A:
Stay in the house, put all ill members in a seperated one. Let the ill people sleep and hope that they will survive. That's the only possibility - but yeah, plague and pest are a pain in the ass.
Q:
ASP.NET MVC attribute
I need to create an attribute which should result in a text area
|
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] |
, testified that he underwrote tens of
thousands of subdivision bonds during his career and none had premiums
that were other than annual or bi-annual. Belinski testified that in his
experience as Lexon’s collections attorney, he never saw an instance where
Lexon did not charge a subdivision bond annually. In its closing argument,
Lexon argued that other GAIs appellants had entered into for bonds
procured by Mahoney Group contained language similar to the Lexon GAIs
“[b]ecause that language, that type of agreement is what’s typical in the
surety industry.” Counsel further argued that Lexon’s witnesses “all
testif[ied] that premiums due on subdivision bonds are always, always due
annually.” Appellants made no objections during Lexon’s closing
argument.
¶19 Arizona Rule of Evidence 701 provides:
Opinion Testimony by Lay Witnesses
If a witness is not testifying as an expert,
testimony in the form of an opinion is limited to
one that is:
(a) rationally based on the witness’s perception;
(b) helpful to clearly understanding the
witness’s testimony or to determining a fact
in issue; and
(c) not based on scientific, technical, or other
specialized knowledge within the scope of
Rule 702.
We find no abuse of discretion. Lexon’s lay witnesses, who all had years of
experience with subdivision bonds, gave testimony rationally based on
their own experience with subdivision bonds, and the testimony was
helpful to determining the facts of the case. Furthermore, appellants
waived their argument concerning Lexon’s closing argument by failing to
make a timely objection below. See Martinez v. Jordan, 27 Ariz. App. 254,
256, 553 P.2d 1239, 1241 (1976) (citing Tryon v. Naegle, 20 Ariz. App. 138, 510
P.2d 768 (1973)).
9
LEXON v. VALLEY SPRINGS et al.
Decision of the Court
D. Attorneys’ Fees and Costs
¶20 Both sides request their attorneys’ fees and costs on appeal
pursuant to A.R.S. § 12-341.01 (2016). We award Lexon reasonable
attorneys’ fees and costs upon compliance with ARCAP 21.
CONCLUSION
¶21 For the foregoing reasons, we affirm the judgment in favor of
Lexon.
AMY M. WOOD • Clerk of the Court
FILED: AA
10
Özet
In the present study, a three-dimensional numerical squid model was generated from a computed tomography images of a longfin inshore squid to investigate fluid flow characteristics around the squid. The three-dimensional squid model obtained from a 3D-printer was utilized in digital particle image velocimetry (DPIV) measurements to acquire velocity contours in the region of interest. Once the three-dimensional numerical squid Model was validated with DPIV results, drag force and coefficient, required jet velocity to reach desired swimming velocity for the squid and propulsion efficiencies were calculated for different nozzle diameters. Besides, velocity and pressure contour plots showed the variation of velocity over the squid body and flow separation zone near the head of the squid model, respectively. The study revealed that viscous drag was nearly two times larger than the pressure drag for the squid's Reynolds numbers of 442500, 949900 and 1510400. It was also found that the propulsion efficiency increases by 20% when the nozzle diameter of a squid was enlarged from 1 cm to 2 cm.Q:
Storing EncFS's config file in SmartCard/Token
I used to store a random generated keyfile in a SmartCard and TrueCrypt was able to access this keyfile using PKCS #11.
I'm trying EncFS now. Some people complain about it storing some of its encryption data (iterations number, salt, etc) in a plain text XML file. These data are valuable for an adversary to hack it, therefore people suggest saving the file in a secure place.
I had then the idea of storing it in a SmartCard/Token. The XML file has a few bytes over 1KB, so any SmartCard should be able to store it.
The issue is that, usually, these keyfiles are read directly by each app using PKCS #11 API. In Windows I'm using EncFSMP for handling EncFS mounting. It only has a checkbox for setting the config file is external, and a simple Open File Dialog for selecting the file in normal file system. There's no PKCS #11 interface as TrueCrypt has.
Anybody has any idea how this could be made work?
I google and found no solution, I suppose nobody would create a software for mounting a SmartCard as a Windows drive, so that it emulates a file system and any app could read a keyfile using good old fopen().
I believe it would be possible to develop an EncFS GUI as EncFSMP, that supports PKCS #11 and reads the keyfile and provides it as the config XML to EncFS, but of course we'd need somebody with EncFS and PKCS #11 skills to do the job.
If there is another software like eCryptFS that supports SmartCard keyfile I'd also like to know. Found nothing till now, it seems that only TrueCrypt has this feature.
A:
I don't think there is anything really sensitive in the.encfs6 (currently named, used to be.encfs5) file, the salt & iterations primarily stop rainbow tables, and may help slightly with a dictionary attack, but if you're using a dictionary word as a passphrase that's what really should change.
Even PGP/GPG encrypted files have the salt & count easily visible, adding -vv will reveal them before the passphrase is asked for:
$ gpg -vv sample.gpg
:symkey enc packet: version 4, cipher 9, s2k 3, hash 2
salt x0x0x0x0x0x0x0x0, count 99999 (99)
gpg: AES256 encrypted data
...
If there were really a security concern with having such data easily visible, PGP/GPG would certainly be doing things differently.
Your efforts may be better spent finding a program to read & use the passphrase stored on a smart card/token, even automatically typing it into any clicked-on window may work, or a macro or similar?
Slightly related: The.encfs6 config file should definitely be backed up somewhere safe, if it were lost then you'd have to try guessing the salt & parameters to get back into your encrypted files, even knowing the passphrase it's not a simple quick task to recover access.
Wangari Maathai was born in Nyeri, Kenya, and was the first woman in East and Central Africa to earn a doctorate. She is the founder of the Green Belt Movement, an environmentalist, a civil society and women’s rights activist, and a parliamentarian. In 2004 she became the first African woman to receive theNobel Peace Prize for her contribution to sustainable development, democracy, and peace.Single-molecule AFM characterization of individual chemically tagged DNA tetrahedra.
Single-molecule characterization is essential for ascertaining the structural and functional properties of bottom-up DNA nanostructures. Here we enlist three atomic force microscopy (AFM) techniques to examine tetrahedron-shaped DNA nanostructures that are functionally enhanced with small chemical tags. In line with their application for biomolecule immobilization in biosensing and biophysics, the tetrahedra feature three disulfide-modified vertices to achieve directed attachment to gold surfaces. The remaining corner carries a single bioligand that can capture and present individual cargo biomolecules at defined lateral nanoscale spacing. High-resolution AFM topographic imaging confirmed the directional surface attachment as well as the highly effective binding of individual receptor molecules to the exposed bioligands. Insight into the binding behavior at the single-molecule level was gained using molecular recognition force spectroscopy using an AFM cantilever tip with a tethered molecular receptor. Finally, simultaneous topographic and recognition imaging demonstrated the specific receptor-ligand interactions on individual tetrahedra. In summary, AFM characterization verified that the rationally designed DNA nanostructures feature characteristics to serve as valuable immobilization agents in biosensing, biophysics, and cell biology.So Blizzard has teamed up with themed board game manufacturer USAopoly to make a World of Warcraft version of Monopoly ($40) and Starcraft version of RISK ($50) due out this summer. Because God forbid you can't get your Warcraft fix when the power goes out. Me? I like to pretend I'm blind and try to shower.
Hit the jump for the possible Warcraft game pieces and a closeup of the board. No more shots of Starcraft, sorry.
World of Warcraft Monopoly® and StarCraft Risk® [battlenet]
via
Blizzard Board Games of the Day [geeks.thedailywh.at]
Thanks to Mark and bryce, who aren't allowed to play board games anymore because they both have anger management issues and have pulled knives on game night.s 13 divide 3346733?
True
Does 303 divide 398445?
True
Does 121 divide 1518408?
False
Does 10 divide 170840?
True
Does 7 divide 26
|
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disabled, you can only sign in by entering your OpenID URL manually:Q:
How to create a submenu with radio buttons in Android?
I have a problem in a simple case (at least, it looks like so). I need to create a submenu for a context menu dynamically and provide each item with a radiobox. I made a lot of trials. When I call menu.setGroupCheckable(0, true, true), where 0 is by default the menu itself, it displays radio buttons to the right on every menu item as expected, but I need this for submenu. So I have the following code:
SubMenu sub = menu.addSubMenu(R.string.name);
int count = 1000;
for(String e : someList)
{
MenuItem item = sub.add(1, count, count, e);
count++;
}
menu.setGroupCheckable(1, true, true);
In this case I don't see neither radioboxes, nor checkboxes in the submenu. Then I wrote the following code:
SubMenu sub = menu.addSubMenu(R.string.name);
int count = 1000;
for(String e : someList)
{
MenuItem item = sub.add(1, count, count, e);
item.setCheckable(true);
count++;
}
menu.setGroupCheckable(1, true, true);
This makes the submenu to have a checkbox in every item, and the checkboxes work exclusively, but I want radioboxes, because they look more intuitively for exclusive selection.
So, how can this be accomplished?
A:
Set the checkableBehavior in xml to single.
Here is some code:
<menu>
<group android:id="@+id/group"
android:checkableBehavior="single">
<item android:id="@+id/menu_sort_by_name"
android:title="@string/action_sort_by_name"/>
<item android:id="@+id/menu_sort_by_last_edit"
android:title="@string/action_sort_by_last_edit"/>
</group>
</menu>
A:
I found out that groups of menus and submenus are processed separately, that is a group formed in a submenu, should be addressed via the submenu, not via the top-level menu. So the solution is to call:
sub.setGroupCheckable(1, true, true);
This code works as expected, that is items in the submenu show radiobuttons instead of checkboxes.
The words "loud, sexy, and inane" pretty much sum up the latest from Zack Snyder. The director of 300 and Watchmen has plenty of visual panache, but when it comes to storytelling, he's a bombastic hack. Sucker Punch is the dark ballad of Babydoll (Emily Browning), a sulking waif committed to a mental institution by her nefarious stepfather after her sister is found dead. A lobotomy awaits, and to gain her freedom, or some semblance of justice, Babydoll drops into alternative planes of reality that involve a sweatshop bordello, where her dance skills rival those of Salome, and a fantasy landscape where she and several other scantily clad inmates battle Nazis, orcs, and dragons. The visuals, backed by a hip soundtrack, offer a ripe spectacle, but the trivial framework and insipid dialogue rupture the spell so often that no dance, no matter how titillating, can punch it up.
HOLLYWOOD, RI-STYLE | July 30, 2014 The 2014 edition will premiere more than 240 films (features, shorts and documentaries) from 62 countries and 34 US states.
GLOBAL CINEMA, LOCAL FLAVOR | August 08, 2013 The 17th annual incarnation of the Rhode Island International Film Festival begins its weeklong run on August 6. The festival, which boasts more than 200 films from 65 countries, is a celebration of the cinematic arts with a campus feel and a focus on all things Rhode Island.
REVIEW: SAFE HAVEN | February 14, 2013 Somewhere along the way Nicholas Sparks went from being just a bestselling author of preachy schmaltz to a full-on franchise (he produces the movies of his books). UNPUBLISHED
UNITED STATES COURT OF APPEALS
FOR THE FOURTH CIRCUIT
UNITED STATES OF AMERICA,
Plaintiff-Appellee,
v.
TODD ERROL VASSELL, a/k/a Eric
Scott, a/k/a Corey Ryan, a/k/a No. 00-7815
Andre Nunes, a/k/a Michael
Derwitt, a/k/a Chris Daley, a/k/a
Tadd Vassell,
Defendant-Appellant.
Appeal from the United States District Court
for the Eastern District of Virginia, at Norfolk.
Rebecca B. Smith, District Judge.
(CR-93-81, CA-00-42)
Submitted: September 28, 2001
Decided: November 26, 2001
Before WIDENER, NIEMEYER, and MOTZ, Circuit Judges.
Dismissed by unpublished per curiam opinion.
COUNSEL
Marcia Gail Shein, LAW OFFICE OF MARCIA G. SHEIN, P.C.,
Decatur Georgia; Charles Haden, Hampton, Virginia, for Appellant.
Laura P. Tayman, OFFICE OF THE UNITED STATES ATTOR-
NEY, Norfolk, Virginia, for Appellee.
2 UNITED STATES v. VASSELL
Unpublished opinions are not binding precedent in this circuit. See
Local Rule 36(c).
OPINION
PER CURIAM:
Todd Vassell appeals a district court’s order denying his motion for
reconsideration of a previous order denying relief on his 28 U.S.C.A.
§ 2255 (West Supp. 2001) motion.
The standard of review of the denial of Fed. R. Civ. P. 60(b)
motions on appeal is abuse of discretion. United States v. Holland,
214 F.3d 523, 527 (4th Cir. 2000). In order to be entitled to relief
under Rule 60(b), it is incumbent upon the movant to show: (1) mis-
take; (2) newly discovered evidence; (3) fraud; (4) that the judgment
is void; (5) that the judgment has been discharged; or (6) any other
reason justifying relief. When the motion raises no new arguments,
but merely requests the district court to reconsider a legal issue or to
change its mind, relief is not authorized. United States v. Williams,
674 F.2d 310, 313 (4th Cir. 1982).
Because we are limited to review of only the denial of the motion
for reconsideration, and Vassell does nothing more than disagree with
the court’s resolution of his § 2255 motion, we deny a certificate of
appealability and dismiss the appeal. We dispense with oral argument
because the facts and legal contentions are adequately presented in the
materials before the court and argument would not aid the decisional
process.
DISMISSED
Sungai Mati
Sungai Mati ('dead river' in Malay) is a small town in, Tangkak (formerly part of Muar District), Johor, Malaysia.
Sungai Mati was named in such a way (dead river) is due to its nature of being an ox-bow lake. It formed or breakaway from main river of Muar River. The "breakaway" cause by a massive flood in early 1900s (not traceable). Before the breakaway Sungai Mati was on the Muar river bank (northern bank) and was a river port.
Before the breakaway Sungai Mati was named 'li hong kang' 利丰港. It means a prosperous port. Until now, the Chinese community still using the same name, which carries both extreme meaning. In fact it was an inland/river port. Muar River and Pahang River in combination was a very important east-west crossing route for traditional river transport. The route called "Laluan Penarikan", which is documented and available in Malaysia secondary history text. The piece of land surrounded by the ex-bow lake and Muar River in combination is called Pulau Penarik.
In early 1970s, there were some remaining traces of the river port. There was landing of jetty at the end of Jalan Raja, the current location of bridge linking Sungai Mati and Pulau Penarik. On the current badminton and tennis court on the left of Jalan Raja, diagonally opposite incumbent Johor Menteri Besar resident, were old warehouses.
Notable residents
Tan Sri Abdul Ghani Othman, the 14th Menteri Besar of Johor.
Category:Towns in Johor
Category:Towns, suburbs and villages in Tangkak
Category:Tangkak District[Ref](http://www
|
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] |
= 3*a**2 - 2*a**2 - 1306 + 1300 + 3*a**3. Calculate r*w(u) + 7*g(u).
-u**3 + 2*u**2 + 2
Let x(y) = y**3 + y**2 - 2*y - 1. Suppose -140*s + 1 = -139*s, -4*u - 8 = -4*s. Let r(o) = -o**2. What is u*r(i) - x(i)?
-i**3 + 2*i + 1
Let c = -3385 - -5239. Let z be (-4)/30 + c/(-270). Let r(l) = l + 7. Let j(y) = 2*y + 10. Determine z*r(x) + 5*j(x).
3*x + 1
Let k(j) = -j**3 - 3*j**2 - j - 4. Let d(n) = -9*n**3 - 13*n**2 + 725*n - 16. What is d(m) - 4*k(m)?
-5*m**3 - m**2 + 729*m
Let u(x) = -x**2 + 2*x. Let g be 6/(20/8 - 3) + -2. Let m = -32 - g. Let f be (3 - 1)/(-2 + (-3)/(-2)). Let v(a) = a**3 + 5*a**2 - 9*a. Give f*v(r) + m*u(r).
-4*r**3 - 2*r**2
Let p(u) = 8*u + 17. Let d(t) = 2*t + 4. Let j = -8 + 6. Suppose 92 = 4*m + 20. Suppose 38*s - m = 36*s. Calculate j*p(x) + s*d(x).
2*x + 2
Let v(d) = 2*d + 4. Let h(m) = -3*m - 309. Give h(u) + 3*v(u).
3*u - 297
Let q(c) = c + 1. Let m(a) be the second derivative of -1/6*a**3 + a + 12 - a**2. Calculate -4*m(z) - 6*q(z).
-2*z + 2
Let y = 322 + -301. Let g(k) = 20*k + 8 - 16*k**2 - 35*k + y*k + 5. Let l(f) = 5*f**2 - 2*f - 4. Calculate 2*g(a) + 7*l(a).
3*a**2 - 2*a - 2
Let z(a) be the first derivative of a - 6448. Let i(c) = -2*c + 8. Determine -i(u) + 4*z(u).
2*u - 4
Let d(m) = -28*m**3 + 2*m**2 + 2*m + 2. Let i(x) = 105 + 81*x**2 - 6*x**2 - 30 + 75*x - 1035*x**3. What is 75*d(n) - 2*i(n)?
-30*n**3
Let n(c) = 22*c**3 - 22*c**2 + 24. Let l = -20070 + 20054. Let u(y) = 7*y**3 - 7*y**2 + 8. Give l*u(x) + 5*n(x).
-2*x**3 + 2*x**2 - 8
Let g(i) be the first derivative of 679*i**3/3 - 119*i**2/2 + 119*i + 23. Let p(q) = -34*q**2 + 6*q - 6. Calculate -6*g(b) - 119*p(b).
-28*b**2
Let y = 50548 + -50554. Let b(l) = -11*l - 31. Let f(t) = -54*t - 154. Let r(p) = 14*b(p) - 3*f(p). Let h(s) = -s - 3. Calculate y*r(j) - 56*h(j).
8*j
Let g be 9*(3 - ((-210)/(-60))/((-6)/(-4))). Let o(s) = 6*s**3 - 6*s + 17. Let d(b) = b**3 - b + 3. What is g*o(n) - 34*d(n)?
2*n**3 - 2*n
Let v(c) = 2*c - 79. Let q(k) = -k + 79. Give 7*q(p) + 6*v(p).
5*p + 79
Suppose -1685*u + 140 = -1657*u. Let f(q) = -7*q**2. Let i(b) = 14*b**2. Determine u*f(s) + 3*i(s).
7*s**2
Let y(j) = -j**2 + j - 1. Let h(a) = -254*a**2 + 234*a - 52. Let b(l) = 51*l**2 - 47*l + 8. Let z(u) = -14*b(u) - 3*h(u). Determine 176*y(i) + 4*z(i).
16*i**2
Suppose -v + 0 + 1 = -o, 5*o + 45 = -5*v. Let q(g) = g. Suppose 3*a = -156 + 15. Let j = a + 48. Let r(u) = 3*u + 3. What is j*r(z) + o*q(z)?
-2*z + 3
Let q(t) = 1247*t. Let b(o) = 700*o + 722*o - 1383*o. Determine -129*b(f) + 4*q(f).
-43*f
Suppose -51*t - 48 = 31*t - 130. Let z(g) = -1. Let r(n) = 9*n**3 + 3*n**2 + 1. Give t*r(h) + 2*z(h).
9*h**3 + 3*h**2 - 1
Suppose -12*u + 14 = 2. Let b(j) = 5*j**2 - 2*j + 3. Let t(g) = 2*g**2 - g + 1. Let o(l) = -b(l) + 2*t(l). Let i(d) = -2 - 1 + 0 - 2. Give u*i(q) - 5*o(q).
5*q**2
Let b be (-588)/(-343) - (-18)/14. Let y(l) = 17*l**3 - 3*l**2 - l - 3. Let q(o) = -16*o**3 + 2*o**2 + o + 2. Give b*q(i) + 2*y(i).
-14*i**3 + i
Let f = -178 + 200. Let n = 20 - f. Let k(x) = -2*x**2 - 2*x. Let s(r) = -r**3 + r**2 + r. Determine n*s(z) - k(z).
2*z**3
Let h(n) = -13*n**3 - n**2 - 12*n + 117. Let i(u) = 5*u**3 + u**2 + 5*u - 58. Calculate 2*h(l) + 5*i(l).
-l**3 + 3*l**2 + l - 56
Let f(v) = -4*v**2 + 4*v - 2. Suppose 4*n + 19 = -7*r + 8*r, -10*r - 32 = -3*n. Let y(b) = 7*b**2 - 8*b + 4. Determine r*f(h) - 3*y(h).
-h**2 + 4*h - 2
Let o(m) = -54*m + 1. Let q(t) = 216*t - 4. Suppose c = 5*p - 27, 0 = 5*c - 86*p + 87*p + 5. What is c*q(r) - 9*o(r)?
54*r - 1
Let p(r) = 20*r**3 - 6*r**2 + r + 5. Let b(v) = -v**3 + v**2 + v - 1. Let l(q) = -5*b(q) - p(q). Let o(u) = 3*u**3 + u. What is -2*l(
|
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AC86U) ASUS AC2900 WiFi Dual-band Gigabit Wireless Router with 1.8GHz Dual-core Processor and AiProtection Network Security Powered by Trend Micro, AiMesh Whole Home WiFi System Compatible (RT-AC86U) Buy Now At Amazon $174.99
vpn884741087.opengw.net:1883 Computer Components bi5jb20+wsB1BBABCAApBQJYmHyZBgsJBwgDAgkQdvNE+jTYSTgEFQgCCgMW The Internet Isn't Safe. That's Why You Need a VPN.
Gry dla dzieci xsBNBFiYfJgBCAC7SIonSZmLIh72w6wcKiDGZkebgVbZ3yd46ls7d3myH0GJ Powerline Adapter Product Use case Rating
Our 13-Step Review Process The 2 GB limit isn’t enough for serious streaming, torrenting or other data-heavy activities
vpn744244776.opengw.net:1609 Air-Filled Toy How to tell if someone is stealing your Wi-Fi Botki męskie Jump up ^ "Trademark Status & Document Retrieval". tarr.uspto.gov. Note: Prices listed here may be subject to change.
Total 86,955 users 78.86 Mbps Warranty & Returns Refurbished & Pre-Owned Phones Moving Supplies & Rentals Plex It is also possible (emphasis on "possible") that VPNs may be able to save net neutrality repeal. Kind of. For those who are unaware, net neutrality is the much-discussed concept that ISPs treat web services and apps equally, and not create fast lanes for companies that pay more, or require consumers to sign up for specific plans in order to access services like Netflix or Twitter. Depending on how ISPs respond to a newly deregulated environment, a VPN could tunnel traffic past any choke points or blockades thrown up by ISPs. That said, an obvious response would be to block or throttle all VPN traffic. We'll have to see how this plays out.
Mask your location Tile macOS Total internet privacy with AVG Secure VPN. On any device.
Alternatively, you can follow our in-depth manuals to set up a VPN connection using the OpenVPN protocol on your router with the Tomato or DD-WRT firmware:
To find a server IP/address name, you need to create VPN configuration files in your personal web office. This guide will help you to figure this out.
Linksys WRT3200ACM Wacom Plug secondary VPN router into computer’s Ethernet jack or connect to it via wireless adapter 1,650.75 GB $('.js-client-isp').html("CyberGhost");
+1 (999+) TV Wall Mount If you wish to temporarily turn off your VPN, you may do so by switching the “Start OpenVPN Client” section to “Disable” under Services > VPN. All your settings will be preserved and you can return to this section at any time to turn the VPN back on.
Rating 4.800012 out of 5 NETWORK SERVICES If you want to purchase an actually pre-configured router (one you will not have to flash yourself), I recommend checking out FlashRouters. FlashRouters offers DD-WRT VPN ready routers with a warranty and an active support team.
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Below was the email I received, I have since removed a device from my list and have not received the credentials to apply OpenVPN to my router…. XKxh0PRsPFyXOytxNFyCSHIXwojN2odL+gN3PTipO1ZiH6uWAMxHZVn21oWU
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Česká republika: Čeština Zioła lecznicze Here’s a step-by-step guide on setting up IVPN in OpenVPN Connect, and here’s a guide for how to set up TorGuard.
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A VPN (virtual private network) can help you surf the web anonymously, securely, and even get around firewalls. Here are the 17 best Android VPN apps!
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Choosing a VPN Service Here are some of the features you can enjoy for free in the meantime:
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To use the standard OpenVPN client (available at the link below) here are a few quick steps to get started:
Smartwatche Huawei Can I flash my HK r7000 with Sabai OS firmware or do I need to purchase a new HK r7000 with the Sabai OS firmware already installed. I am not seeing a flash option on there site but I might be missing something. I assume this replaces dd-wrt correct?
Get simultaneous top-class protection on up to 7 devices with a German-made software, available on Windows, Mac, iOS and Android platforms.
Faculty Housing Flickr No iOS native app. If you’re looking for a VPN for your iPhone or iPad, you should choose a different one
Sorry, but we don’t have a universal step-by-step instruction. SAVE {{orderCtrl.getSavingCoupon()}}% 26,448
355,932 9.1 If you want to use a VPN on many devices, installing one on your router might be the best solution.
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While we’d strongly urge you to read over that entire guide before proceeding we understand you might be in a let’s-just-get-this-done mood. Let’s quickly highlight what to look for in a VPN intended for home router use and then highlight our recommendation (and the VPN we’ll be using for the configuration portion of the tutorial).
If you already have any VPN provider listed on this page and want support for your existing router, then you can purchase a FlashRouters VPN suport Plan.
Content Manager & Internet Security Writer Best VPN overall Baby & Kids General Instructions 502.95 GB Circle® with Disney Folding Knives
AppleIsGR8 Mophie You’ll find USB ports on many routers, but it’s important to find out what that port is used for. On some routers, it’s merely a means of transferring setup information (network ID and password, for example) from the router to a client via a USB memory key. Better routers will allow you to plug in a USB mass-storage device to add NAS (network-attached storage) functionality. Plug a large USB hard drive into your router and every device on your network will have access to that storage resource — it’s like having a cheap server.
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MSRP: $208.99 Online Banking 4 ports 17 Dyson Private browsing for 6,99€ a month Worldwide OpenVPN and PPTP Support
Innovation ERP Television + Work with Netflix sol TCP: 1309 Budget pick: TorGuard
Sign Up 500+ Servers browsing privately Case Studies Nikon Only downside? They can take 30 days to process any refunds. Kinda a hassle. But based on their results, you probably won’t even need that refund, anyway.
Read article In order to prevent DoS attacks we show only some portion of available servers. internet speed router
Manage Privacy Preferences Pay Your Credit Card Português Other “ VPN Router” providers outsource various pieces to third parties, don’t include Private Internet Access (or PIA for short) came in as the fourth fastest VPN overall.
Total 1,261 users 12.48 Mbps WL - WNN522N2 300Mbps Router Extender Range Extender WiFi Repeater $200.01 - $500 10
4.5(2,895 Reviews) Tech Harmonica Note: The fastest VPN routers from the list above are the bottom two options with AES-NI encryption acceleration processors.
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|
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] |
iberium War. It is unknown what happened to LEGION when Kane and Nod ascended.Q:
Sum the different date total
I have following data in my sql table:
Tran_Date | Amount
2013-05-01 20:09:49 | 50.00
2013-05-02 04:09:49 | 50.00
2013-05-02 20:09:49 | 500.00
I want sum the amount before next day 5am. The result should as below.
Amount
100.00
500.00
I have try the following code,but the result is wrong:
SELECT DATEADD(hh, 5, DATEADD(dd, DATEDIFF(dd, 0, DATEADD(dd,1,f.TRAN_DATE)) AS sDate,
SUM(Amount)
FROM TRAN_TABLE
GROUP BY sDate
How do acheive this? thanks
A:
For any SQL Server version
select [Date]=DATEADD(DAY,DATEDIFF(DAY,0,DATEADD(HOUR,-5,Tran_Date)),0),
Total=SUM(Amount)
from tbl
group by DATEADD(DAY,DATEDIFF(DAY,0,DATEADD(HOUR,-5,Tran_Date)),0)
order by [Date];
For SQL Server 2008+, you can use the DATE data type
select [Date]=CAST(DATEADD(HOUR,-5,Tran_Date) as date),
Total=SUM(Amount)
from tbl
group by CAST(DATEADD(HOUR,-5,Tran_Date) as date)
order by [Date];
A:
You need to extract a DATE after subtracting 5 hours and group by that:
SELECT
CAST(DATEADD(hour, -5, TRAN_DATE) AS DATE) AS sDate,
SUM(Amount)
FROM TRAN_TABLE
GROUP BY CAST(DATEADD(hour, -5, TRAN_DATE) AS DATE)
about
With more than 1.5 million copies of the New York Times Bestselling McCarthys of Gansett Island Series sold since MAID FOR LOVE debuted in April 2011, this series has quickly become a fan favorite!
HOPING FOR LOVEAll her life, Grace Ryan was the "fat girl." Taunted and teased and ignored by her peers, she tried every diet ever invented to no avail. Desperate to change her life as her twenties slipped away, she decided it was time for drastic measures and had lap-band surgery. More than a year later, she's lost 130 pounds and is venturing into the dating world for the first time. During a boat trip to Gansett Island with the new guy in her life, Grace refuses to have sex with him and finds herself abandoned without a dollar to her name at McCarthy's Gansett Island Marina.
At home for the summer awaiting the launch of his debut CD, music star-in-the-making Evan McCarthy is performing at the Tiki Bar when he notices Grace looking lost in a sea of happy people. Evan comes to her aid and quickly finds himself smitten. But the last thing Grace needs after all she's been through is a guy who "doesn't do relationships." Will Evan change his ways to win Grace's heart?
""Another solid entry into the McCarthy's of Gansett Island series. Marie Force continues to create characters that readers can identify with and make you want to visit fictional Gansett Island and its residents."" -Night Owl ReviewsPatio Mallorquin Galaxy S5 Case
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Patio Mallorquin galaxy s5 case by Lizzy Forrester. Protect your Galaxy S5 with an impact-resistant, slim-profile, hard-shell case. The image is printed directly onto the case and wrapped around the edges for a beautiful presentation. Simply snap the case onto your Galaxy S5 for instant protection and direct access to all of the phone's features!
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Protect your Galaxy S5 with an impact-resistant, slim-profile, hard-shell case. The image is printed directly onto the case and wrapped around the edges for a beautiful presentation. Simply snap the case onto your Galaxy S5 for instant protection and direct access to all of the phone's features!
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About Lizzy Forrester
LIZZY FORRESTER'S FINE ART STORE
Lizzy is based in the Balearic Islands, though spends much of her time travelling now, with several exhibitions yearly, usually Beijing, Canton, New York and a few in Europe. Her works form part of collections world wide, and her work has been recognised with a number of awards.
She also works as a 'Spirit Artist' using art as a tool for healing, and at times, working as a medium to provide evidence of Spirit. Please contact her for more information on this work.
Past recent Exhibitions, Beijing Intl Art Expo, and Art Canton, Miami Spectrum, Bastille Paris Exhibition, Hong Kong 'Asia Contemporary Art show to name a few.
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Should Prince Harry have been in Afghanistan?
Prince Harry is back in the UK after fighting the Taleban on the front-line in Afghanistan for the past 10 weeks.
The 23-year-old's service was kept secret after the prince's planned tour to Iraq last year had to be cancelled because of a security risk sparked by publicity.
So what do you think of Prince Harry having been at the front line?
Do you think he should still be allowed to fight like a normal soldier or do you think his fame makes him and his colleagues a target?
Is it right that he was brought home or perhaps you think it's all a fuss over nothing?
Whatever your view, we want to hear from you.
Unfortunately this topic is now closed but there are Comments pages on other subjects on the main Chat index
Your comments
"I think Harry should be able to do what he likes. I've seen the pictures of him in Afghanistan and it looks like he enjoyed it. I think Harry would make a great soldier."
Jessica, 12, London, England
"Francesca is right - he is over 18 and he shouldn't be mollycoddled because he DOES have a brain himself!"
Hanna, 13, Glasgow, Scotland
"Harry should follow his heart and do what he thinks is right."
Eleanor, 12, Eastcote, England
"I think its good that they let him go out there. Plus it's giving him a chance to be a normal person."
Beth, 10, Langbank, Scotland
"He should have stayed because he wanted to. He might be the Queen's grandson, but everybody is the same - and he should have stayed there like all the other soldiers."
Sean, 12, Bangor, Wales
"I believe Prince Harry did a good deed. He is a prince and he should represent his country."
Edward, 13, Bolton, England
"Prince Harry is a member of the Royal Family but....if he wants to fight out there then he should be able to because he is fighting for his country and one day he could be king!!!"
Laura, 13, Ipswich, Suffolk
"I think he should be allowed because he just wants to do his job."
Darcy, 10, Barnsley, England
"I think that Prince Harry was right to go to Afghanistan. He's trying to fight for Queen and country and show that the Royal Family don't just sit there and do nothing. It's not like he's the only royal to go to war, kings always used to fight on the front lines! Good On You Harry."
Beth, 13, Northampton England
"I think if Prince Harry would like to fight in Afghanistan, well let him!"
Sarah, 10, Penrith, England
"Harry is a willing prince who feels like fighting for his country. There is nothing wrong with that."
Charlie, 12, London, England
"Of course he should be allowed to fight in Afghanistan! It's his life and I think it is brilliant that a prince is so willing to fight for his country!!
GOOD ON YOU HARRY!!!"
Reuben,
|
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with supersets $V$ of the argmin set $V_0$, rather than with the argmin set itself, turns out to be essential in non-parametric settings.
We are now prepared to state the following conditions on the studentized stochastic process and estimators of the superset.[^6]
Let $V$ be a superset of $V_0$, that is, $V_0 \subseteq V$. For some sequence of nonnegative normalizing constants $a_n$ and $b_n$, we have that the normalized supremum of the studentized process $a_n \cdot ( \sup_{v \in V} Z_n(v)- b_n)$ can either be **(a)** approximated in distribution by a variable $\mathcal{E}_{\infty}(V)$, namely $$a_n \cdot (\sup_{v \in V}
Z_n(v) - b_n) =_d \mathcal{E}_{\infty}(V) + o_p(1),$$ or **(b)** approximately majorized in distribution by a variable $\mathcal{E}_\infty(V)$, namely $$a_n \cdot (\sup_{v \in V} Z_n(v) - b_n) \leq_{d} \mathcal{E}_\infty(V)
+ o_p(1),$$ where $\mathcal{E}_{\infty}(V)$ has a known continuous distribution function.
This is a basic asymptotic condition, which either requires standard convergence in distribution or majorization in distribution by a limit random variable with a continuous distribution function. We also consider the following generalization of C.1 which is useful for our purposes.
Let $V$ be a superset of $V_0$, that is, $V_0 \subseteq V$. For some sequence of nonnegative normalizing constants $a_n$ and $b_n$, we have that the normalized supremum of the studentized process $a_n \cdot ( \sup_{v \in V} Z_n(v)- b_n)$ can either be **(a)** approximated in distribution by a variable $\mathcal{E}_{n}(V)$, namely $$a_n \cdot (\sup_{v \in V}
Z_n(v) - b_n) =_d \mathcal{E}_{n}(V) + o_p(1),$$ or **(b)** approximately majorized in distribution by a variable $\mathcal{E}_n(V)$, namely $$a_n \cdot (\sup_{v \in V} Z_n(v) - b_n) \leq_{d} \mathcal{E}_n(V)
+ o_p(1),$$ where $ \mathcal{E}_n(V) = O_p(1)$ has a known distribution and satisfies a sequential continuity or anti-concentration property, specifically that for any sequence $\epsilon_n \searrow 0$, $$\label{eq:AC}
\sup_{x \in \Bbb{R}} P [ |\mathcal{E}_n(V) - x| \leq \epsilon_n ] \to 0.$$
Conditions C.1 or C$^*$.1 justify the use of quantiles of $\mathcal{E}_{\infty}(V)$ or $\mathcal{E}_n(V)$, respectively, for inference. Condition C.1(a) requires that the supremum of the normalized process $Z_n(v)$, appropriately studentized, converges in distribution to the random variable $\mathcal{E}_{\infty}(V)$. As shown in section 3, it applies with either parametric or nonparametric kernel estimation of the bound-generating function $\theta(\cdot)$. Condition C.1(b) is a weaker condition that does not require the studentized supremum of $Z_n(v)$ to have an asymptotic distribution, but only requires that its distribution can be majorized by that of $\mathcal{E}_{\infty}(V)$. Section 3.4 establishes its validity for nonparametric series estimation of the bound-generating function. Note that by the term “known distribution," in reference to $\mathcal{E}_{\infty}(V_0)$ and $\mathcal{E}_n(V)$, we mean a distribution whose parameters can be estimated consistently. Also, instead of using standard convergence in distribution notation, we employ strong approximation, which is without loss of generality relative to the former due to the Skorohod-Dudley-Wichura construction. In general, the normalizing constants $a_n$ and $b_n$ may depend on $V$ and can be different depending on which of C.1(a) and C.1(b) hold.
Condition C$^*$.1 is a generalization of C.1, which allows for the use of some intermediate or penultimate approximations for inference. For example, in the case of series approximation we can approximate the supremum of the process $Z_n(v)$ by the supremum $\mathcal{E}_n(V)$ of a Gausssian process, which does not in general converge to a fixed random variable, but can instead be majorized in distribution by an exponential random variable $\mathcal{E}_{\infty}(V)$. However, this majorization can be conservative. We can instead use the quantiles of $\mathcal{E}_n(V)$ for inference, which in our experience provides a more accurate, less conservative approximation. In order for the penultimate approach to be valid, we require the sequential continuity, or anti-concentration, property (\[eq:AC\]) for the sequence of random variables $\mathcal{E}_n(V)$. This property is needed for the disappearance of the effect of approximation errors in critical values on the coverage probabilities. If $\mathcal{E}_n(V)$ has a continuous limit distribution the anti-concentration property follows automatically. If $\mathcal{E}_n(V)$ does not have a limit distribution, verification of this property is a harder problem, which can be achieved either numerically or, in some limited cases, analytically using exact versions of Hotelling’s tubing method. Analytical limitations arise because little is known about the anti-concentration properties of the suprema of a sequence of Gaussian processes, in contrast to a vast knowledge on the concentration properties of such processes (see however [@RV:AC], [@RV:LO] and [@TV:LO] for a discussion of anti-concentration inequalities for some “simpler" related problems).
The next condition deals with the effect of estimating the approximate argmin sets.
Let $\widehat V$ denote any sequence of sets, possibly data-dependent, that contain a superset $V$ of $V_0$, with probability approaching one, and that converge to $V$ at the rate $r_n$, i.e., $d_H(\widehat V, V) \leq O_p(r_n)$, where $r_n$ is a sequence of constants converging to zero. Also, let $\widehat{a}_n$ and $\widehat{b}_n$ denote corresponding, possibly data-dependent, normalizing constants. Then the normalized supremum of the studentized stochastic process is insensitive to the replacement of the superset $V$ and normalizing constants $(a_n,b_n)$ with the estimates $\widehat V$ and $(\widehat{a}_n,\widehat{b}_n)$, namely $$\widehat{a}_n \cdot (\sup_{v \in \widehat V} Z_n(v) - \widehat{b}_n) - a_n \cdot (\sup_{v \in V} Z_n(v) - b_n) \to_p 0.$$
This assumption allows for a data-dependent choice of $\widehat
V$, but requires that $\widehat V$ should eventually settle down at $V$, without affecting the supremum of the studentized stochastic process. In Section 3.6, we construct such estimators from the level sets of the estimated bound-generating function $v \mapsto \widehat \theta(v)$ and show that these estimators converge to the level sets of $v
\mapsto \theta(v)$ at a rate sufficiently fast not to affect the behavior of the supremum of the estimated process. In nonparametric settings, this may sometimes require that level sets are strictly larger than the argmin set $V_0$.
We now state our first main result under the above conditions.
\[Theorem 1\] Let $$\widehat \theta_{p} = \inf_{ v \in \widehat V} [\widehat \theta (v) +
[\widehat b_n + \widehat c(p)/\widehat a_n]s(v) ],$$ where $\widehat c(p)$ is defined below.
1\. Suppose that conditions C.1(b) or C$^*$.1(b) and C.2 hold and that $\widehat c(p)$ is a consistent upper bound on $c_n(p):=$ the $p-th$ quantile of $\mathcal{E}_{n}(V)$, where $n = \infty$ under C.1(b), namely $$\widehat c(p) \geq c_n(p) + o_p(1).$$ Then we have that the estimator $\widehat \theta_p$ is downward $p$-quantile unbiased, namely $$\liminf_{n \to \infty} P[\theta_0 \leq \widehat \theta_{p}] \geq p.$$ 2. Suppose conditions C.1(a) or C$^*$.1(a) and C.2 hold with $V
= V_0$ and that $\widehat c(p)$ is a consistent estimate of $c_n(p):
|
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48968,
16064,
275,
26229,
13,
21753,
15,
187,
187,
13788,
6876,
187,
187,
688,
9178,
13,
12521,
11448,
428,
970,
253,
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11835,
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428,
347,
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247,
3558,
273,
253,
3961,
380,
380,
342,
12429,
7902,
13,
15602,
327,
253,
2014,
2802,
2861,
287,
735,
451,
20772,
457,
347,
43982,
285,
17898,
382,
15,
496,
13563,
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16460,
13,
344,
4546,
27275,
347,
247,
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273,
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285,
253,
353,
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284,
13,
15602,
327,
616,
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5400,
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85,
5924,
285,
10440,
272,
253,
5400,
434,
3835,
28,
285,
969,
347,
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49298,
382,
285,
5400,
24996,
323,
616,
956,
14,
484,
5400,
13,
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420,
285,
308,
410,
2921,
187,
187,
35769,
11448,
369,
671,
43982,
275,
380,
380,
434,
12429,
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457,
84,
1930,
2199,
380,
35309,
18145,
13,
665,
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275,
11299,
13,
380,
10063,
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15,
187,
187,
8665,
187,
510,
12980,
28780,
273,
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457,
84,
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342,
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275,
253,
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281,
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275,
34370,
10520,
457,
84,
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2014,
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2014,
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2014,
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10,
187,
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187,
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2014,
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510,
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2014,
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187,
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187,
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275,
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13,
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13,
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10,
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273,
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13,
533,
253,
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434,
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342,
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15,
187,
187,
510,
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398,
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253,
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285,
407,
253,
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598,
275,
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13,
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497,
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85,
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285,
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253,
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13,
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15,
187,
187,
3,
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285,
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13,
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15,
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15,
346,
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13,
253,
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285,
253,
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273,
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310,
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187,
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13,
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275,
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911,
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285,
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253,
806,
16665,
273,
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387,
253,
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273,
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15,
187,
187,
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15,
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13,
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337,
13,
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273,
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326,
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253,
16583,
347,
352,
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253,
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2170,
13,
2556,
281,
4400,
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15,
50,
27,
187,
187,
19013,
33616,
6563,
2009,
18319,
27599,
187,
187,
42,
1849,
644,
4715,
28551,
495,
285,
256,
515,
323,
1390,
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15,
28814,
13,
309,
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2820,
281,
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247,
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2009,
326,
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672,
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1979,
310,
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9098,
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15,
1244,
352,
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13,
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672,
309,
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327,
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13,
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13,
352,
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13,
840,
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15,
187,
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310,
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27,
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15,
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16,
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32,
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13,
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13,
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187,
187,
15,
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551,
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14,
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36,
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28,
190,
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94,
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15,
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247,
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14,
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27,
346,
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255,
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14,
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27,
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28,
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14,
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27,
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28,
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27,
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27,
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27,
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14,
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27,
346,
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27,
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10,
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of Bowery's life entitled Xtravaganza: Staging Leigh Bowery that was held at the Kunsthalle Wien museum in Vienna, Austria.
Musician
In 1980, Ashworth - using the pseudonym Triash - as briefly a member of the band The The with Matt Johnson, appearing on the single ‘Controversial Subject’ as drummer and vocalist. In 1982–1983, he played drums as a member of Marc and the Mambas, appearing on their debut album Untitled and photographing the album's cover; and again as band percussionist and album photographer for their follow-up album, Torment and Toreros
Ashworth was also drummer in The The's Matt Johnson’s side project The Gadgets, who produced one album in 1983, The Blue Album.
Other
The ubiquity of Ashworth’s photographic work with music artists in the eighties led to him being mentioned in Mari Wilson’s UK Top 10 hit song ‘Just What I Always Wanted’
(The lyrics also namecheck the song's writer, Teddy Johns, though 'Teddy' is often misheard as 'Tenney')
“I've got a mink from Paris, a ring from Rome
A whole new wardrobe in my home
A tune from Teddy, an Ashworth snap
These are the landmarks on my map
I've got just what I always wanted”
Exhibitions
Solo
Mavericks - Lever Gallery, London, 2018.
Mavericks Photographic Show - The Gallery, Liverpool, 2018
Contributor
Street Style: From Sidewalk to Catwalk - V&A, London
Hats: An Anthology by Stephen Jones - V&A, London
The House of Annie Lennox - V&A, London
Otherness - Louis Vuitton Gallery, Paris
Books
Contributor
Fetish: Masterpieces of Erotic Fantasy Photography by Michelle Olley
Selected album, EP and single cover photography
Tar (Visage's first single, 1979)
Kings of the Wild Frontier (Adam and the Ants, 1980)
Visage (Visage, 1980)
Non-Stop Erotic Cabaret (Soft Cell, 1981)
Bedsitter (song) single (Soft Cell, 1981)
In the Garden (Eurythmics, 1981)
Careless Memories (Duran Duran's second single, 1981)
Sticky George (The Korgies, 1981)
Uncertain Smile single (The The, 1982)
Touch (Eurythmics, 1983)
You Are in My System (Robert Palmer, 1983)
Making History (Linton Kwesi Johnson, 1983)
Doppelganger (Kid Creole and the Coconuts, 1983)
Welcome To The Pleasuredome, (Frankie Goes To Hollywood, 1984)
Vermin in Ermine (Marc Almond, 1984)
Bananarama (Bananarama, 1984)
Doctor! Doctor! (Thompson Twins, 1984)
Private Dancer (Tina Turner, 1984)
Sophisticated Boom Boom (Dead Or Alive, 1984)
Addicted to Love (Robert Palmer, 1986)
The Foolish Thing to Do (Heaven 17, 1986)
Saint Julian (Julian Cope, 1987)
Holy Water (The Triffids song) (The Triffids, 1987)
Outrider (Jimmy Page, 1988)
Malafemmina (Gianna Nannini, 1988)
Different (Thomas Anders, 1989)
And Now the Legacy Begins (Dream Warriors, 1991)
Devil Hopping (Inspiral Carpets, 1994)
Das Ist Ein Groovy Beat, Ja (Jake Slazenger, 1996)
Hearts and Knives (Visage, 2013)
Late Night Tales: Röyksopp (various artists, 2013)
External links
Peter Ashworth
Peter Ashworth : Mavericks
Facebook
The Guardian illustrated interview
References
Category:Year of birth missing (living people)
Category:Living people
Category:English rock drummers
Category:English photographers
Category:The The members
Category:Marc and the Mambas membersFed agents bust smuggling ring tunneled under US-Mexico border
U.S. federal agents have arrested four people and seized nearly 3,000 pounds of marijuana in an operation to bust a drug smuggling ring that had tunneled under the U.S.-Mexico border, federal prosecutors said on Wednesday.
The smugglers built a house to hide the northern entrance to the 400-yard (365 meters) tunnel in Calexico, the U.S. Attorney's Office for southern California said.
The southern end of the tunnel came up in El Sarape restaurant in Mexicali, authorities said.
It is the first smuggling tunnel found in more than 10 years in Calexico, a small city of about 40,000 people some 120 miles (193 km) east of San Diego, but the 12th discovered along Mexico's border with California since 2006.
The smugglers purchased the land last April and by the time construction wrapped up in December, federal investigators were using wiretaps and watching activity at the house, charging documents said.
"This house and tunnel were constructed under the watchful eye of law enforcement," said Laura Duffy, U.S. Attorney for southern California. "For the builders, the financiers and the operators of these passageways, there is no light at the end of the tunnel."
Federal agents continued to monitor the house, a separate safe house in Calexico and four suspects until the first loads of marijuana came through at the end of February.
On Mar. 7, investigators seized 1,350 pounds of pot that came through the tunnel as it was being transported through the Los Angeles area, according to federal documents.Q:
Collapsing navbar instantly closes
I've been learning bootstrap 3 and sass for last few days. Anyway, I'm trying to make a navbar that collapses when screen size is below 1000px. And it works, but when I click on toggle button, to show menu dropdown, it opens, then instantly closes.
Here is the code: http://jsbin.com/zahatekisa/edit?html,css,output
.navbar {
background-color: #202C39;
}
div.navbar-header a.navbar-brand {
font-family: "Caveat Brush";
margin-right: 20px;
font-size: 23px;
color: #F29559;
}
div.navbar-header a.navbar-brand:hover {
color: #ffb36b;
}
ul.nav.navbar-nav li a {
font-family: "PT Sans", "cursive";
color: #e6e6e6;
}
ul.nav.navbar-nav li a:hover {
color: #ffffff;
background-color: #2a394a;
}
ul.navbar-right li p.navbar-text {
display: block;
}
@media (max-width: 1050px) {
ul.navbar-right li a {
float: left;
}
ul.navbar-right li p.navbar-text {
margin-left: 15px;
position: relative;
top: -4px;
}
}
@media (max-width: 1000px) {
.navbar-header {
float: none;
}
.navbar-toggle {
display: block;
}
.navbar-collapse {
border-top: 1px solid transparent;
box-shadow: inset 0 1px 0 rgba(255, 255, 255, 0.1);
}
.navbar-collapse.collapse {
display: none!important;
}
.navbar-nav {
float: none!important;
margin: 7.5px -15px;
}
.navbar-nav > li {
float: none;
}
.navbar-nav > li > a {
padding-top: 10px;
padding-bottom: 10px;
}
}
<script src="https://ajax.googleapis.com/ajax/libs/jquery/2.1.1/jquery.min.js"></script>
<script src="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.6/js/bootstrap.min.js"></script>
<link href="https://maxcdn.bootstrapcdn.com/bootstrap/3.3.6/css/bootstrap.min.css" rel="stylesheet"/>
<nav class="navbar navbar-default navbar-fixed-top">
<div class="container">
<div class="navbar-header">
<!--Making the toggle button-->
<button type="button" class="navbar-toggle" data-toggle="collapse" data-target="#myNavbar">
<span class="sr-only">Toggle navigation</span>
<span class="icon-bar"></span>
|
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] |
of the HAC aggravator.
Because federal courts defer to this Court's interpretation of Florida law,[5] our construction of the statutory language defining HAC is crucial to its constitutional validity. Just months after the Florida Legislature amended the death penalty statute to conform to Furman, this Court stated with regard to HAC:
It is our interpretation that heinous means extremely wicked or shockingly evil; that atrocious means outrageously wicked and vile; and, that cruel means designed to inflict a high degree of pain with utter indifference to, or even enjoyment of, the suffering of others. What is intended to be included are those capital crimes where the actual commission of the capital felony was accompanied by such additional acts as to set the crime apart from the norm of capital felonies the conscienceless or pitiless crime which is unnecessarily torturous to the victim.
State v. Dixon, 283 So.2d 1, 9 (Fla.1973). Relying on this construction as a limitation of HAC to the "conscienceless or pitiless crime which is unnecessarily torturous to the victim," the United States Supreme Court held in Proffitt v. Florida, 428 U.S. 242, 255-56, 96 S.Ct. 2960, 49 L.Ed.2d 913 (1976), that this definition gave the sentencer adequate guidance in its application. Subsequently, in Sochor v. Florida, 504 U.S. 527, 112 S.Ct. 2114, 119 L.Ed.2d 326 (1992), the Supreme Court rejected an Eighth Amendment challenge to the HAC aggravator, but did so in terms that called into question our HAC jurisprudence:
Sochor contends... that the State Supreme Court's post-Proffitt cases have not adhered to Dixon's limitation as stated in Proffitt, but instead evince inconsistent and overbroad constructions *963 that leave a trial court without sufficient guidance. And we may well agree with him that the Supreme Court of Florida has not confined its discussions on the matter to the Dixon language we approved in Proffitt, but has on occasion continued to invoke the entire Dixon statement quoted above, perhaps thinking that Proffitt approved it all. See, e.g., Porter v. State, 564 So.2d 1060 (1990), cert. denied, 498 U.S. 1110, 111 S.Ct. 1024, 112 L.Ed.2d 1106 (1991); Cherry v. State, 544 So.2d 184, 187 (1989), cert. denied, 494 U.S. 1090, 110 S.Ct. 1835, 108 L.Ed.2d 963 (1990); Lucas v. State, 376 So.2d 1149, 1153 (1979).
But however much that may be troubling in the abstract, it need not trouble us here, for our review of Florida law indicates that the State Supreme Court has consistently held that heinousness is properly found if the defendant strangled a conscious victim.
Id. at 536-37, 112 S.Ct. 2114 (citations omitted). In response to Sochor, this Court clarified that for HAC to apply, "the crime must be both conscienceless or pitiless and unnecessarily torturous to the victim." Richardson v. State, 604 So.2d 1107, 1109 (Fla.1992); see also Hartley v. State, 686 So.2d 1316, 1323 (Fla.1996). We have also stated that "[o]nly when a murder evinces extreme and outrageous depravity as exemplified either by the desire to inflict a high degree of pain or utter indifference to or enjoyment of the suffering of another is a finding of HAC appropriate." Buckner v. State, 714 So.2d 384, 390 (Fla.1998).
This Court has repeatedly held that HAC applies to murders either by strangulation of a conscious victim, as noted in Sochor,[6] or by repeated stabbing of a conscious victim,[7] because a killing by either method is inherently torturous:
HAC focuses on the means and manner in which the death is inflicted and the immediate circumstances surrounding the death, rather than the intent and motivation of a defendant, where a victim experiences the torturous anxiety and fear of impending death. Thus, if a victim is killed in a torturous manner, a defendant need not have the intent or desire to inflict torture, because the very torturous manner of the victim's death is evidence of a defendant's indifference. Because strangulation of a conscious victim involves foreknowledge and the extreme anxiety of impending death, death by strangulation constitutes prima facie evidence of HAC.
Barnhill v. State, 834 So.2d 836, 849-50 (Fla.2002) (citations omitted). Thus, only "where" and "if" the killing is inherently torturous such as in the case of a strangulation or repeated stabbing of a conscious victim will the defendant's intent or indifference to the victim's suffering be inferred by the very torturous manner of the death.
Applying these criteria, we have disapproved HAC for gunshot murders that are unaccompanied by other circumstances showing that the killing was conscienceless or pitiless and unnecessarily torturous to the victim, i.e., committed in a manner exhibiting utter indifference to or enjoyment of the suffering of another. See, e.g., *964 Diaz v. State, 860 So.2d 960, 967 (Fla.2003) (determining that competent, substantial evidence did not support HAC finding for murder carried out quickly and without intent to inflict a high degree of pain or otherwise torture the victim), cert. denied, ___ U.S. ___, 124 S.Ct. 2068, 158 L.Ed.2d 622 (2004); Rimmer v. State, 825 So.2d 304, 328 (Fla.2002) (finding that evidence did not support HAC where the record did not reveal that the defendant tortured the victims or subjected them to pain and suffering), cert. denied, 537 U.S. 1034, 123 S.Ct. 567, 154 L.Ed.2d 453 (2002); Ferrell v. State, 686 So.2d 1324, 1330 (Fla.1996) ("Execution-style killings are not generally HAC unless the state has presented other evidence to show some physical or mental torture of the victim."); Robinson v. State, 574 So.2d 108, 112 (Fla.1991) (holding that the trial court erred in finding HAC because the fatal shot to the victim "was not accompanied by additional acts setting it apart from the norm of capital felonies, and there was no evidence that it was committed `to cause the victim unnecessary and prolonged suffering'"). In fact, we have stated that "a murder by shooting, when it is ordinary in the sense that it is not set apart from the norm of premeditated murders, is as a matter of law not [especially] heinous, atrocious, or cruel." Lewis v. State, 398 So.2d 432, 438 (Fla.1981) (emphasis supplied).
Turning to the facts of this case, I conclude that Geoffrey Flaherty suffered a nearly instantaneous death by gunshot that was not inherently torturous under the standards of our previous opinions. Cf. Rimmer, 825 So.2d at 329 (holding HAC inapplicable where second victim was "killed within a very short time (perhaps only seconds) after [the first victim] and, therefore, would have experienced only a very short period of mental anguish, if any at all"). In these circumstances, both the trial court in finding HAC and this Court in reviewing that finding are obligated to determine whether the defendant committed the killing in an unnecessarily torturous manner that exhibited an utter indifference to or enjoyment of the suffering of the victim. Neither the sentencing order nor the majority opinion in this case reflects such a determination. The trial court found that in firing the fatal shot, Hutchinson acted "without pity, without conscience." This entirely accurate observation does not equate to a finding that the killing was done in an unnecessarily torturous manner. The majority, in approving the trial court's determination, explicitly limits its focus to "the victim's perceptions of the circumstances, as opposed to those of the perpetrator." Majority op. at 28. Accordingly, I believe that in approving the trial court's determination that this murder was HAC without taking into consideration the defendant's intent, the majority has strayed from HAC's Eighth Amendment boundaries.
The majority's exclusive focus on the victim's possible or likely perceptions in its review of the HAC determination in this case perpetuates an error that I have previously commented upon. See Francis v. State, 808 So.2d 110, 144 (Fla.2002) (Pariente, J., concurring in result only) (emphasizing "that a finding of HAC under Dixon and its progeny requires evidence from which it can be inferred that the defendant intended to inflict unnecessary pain or suffering upon the victim, otherwise torture the victim, or exhibit indifference to the suffering of another"). Justice Harding has articulated a similar concern in a case in which we struck HAC for an "execution-style" killing:
If we approved the application of the HAC aggravating factor in the instant case without some factual proof of the victims' mental torture, then the factor *965 would apply in every instance where a normal person might feel fear. This would exclude only those homicides where the victim was ambushed or killed without awareness of the assailant. This clearly would go far beyond finding the HAC factor to be "appropriate in a `conscienceless or pitiless crime which is unnecessarily torturous to the victim.'" Richardson, 604 So.2d
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process move forward or backward in time, which will have the pair move forward or backward along the path. However, Arina and Frendt's interactions with the environment remain mutable with time. For example, the player may need to have Arina work forward in time to grab a sphere of light for the lantern, move time backward for her to place it on a jumping cube, and then continue to move forward pass a fog bridge to recollect the cube later. The player cannot move time forward or past a point where either Arina or Frendt cannot progress. Separately, Frendt's ability to interact with devices that control the flow of time for objects in the level may be needed to create paths previously blocked, bring falling light flowers into close proximity to Arina's paths, or similar motions. Other solutions may require lateral thinking that recognizing how the various time stream manipulations can work.
Once the player has completed a set of levels, they are presented with a short scene of Arina and Frendt involved in these activities, where a hidden jumping cube can be found using similar time manipulation controls. This completes a constellation, which once the final level is completed, merge into a final memory.
Development
The Gardens Between was developed by the Australia studio The Voxel Agents. Lead designer and animator Josh Alan Bradbury stated that the game was meant to be an allegory for how one looks back at childhood friends when they become older. Bradbury described how Arina and Frendt are not necessarily the most compatible friends - Arina is shown more adventurous and outgoing, while Frendt is shy and seeks intellectual pursuits - and as an adult may make little sense how they developed a friendship, but through the lens of their shared childhood memories, one is able to see how their friendship developed. The time manipulation mechanics was representative of trying to relive these childhood memories, running through them back and forth in order to recall them correctly. In another interview, executive producer and level designer Simon Joslin revealed that the time manipulation mechanics started with the idea of turning the timeline interface of the movie Minority Report into a game. "The experience of using a timeline to review and inspect scenarios felt fascinating, and embryonic of intricate, quizzical experiences."
The game's soundtrack was composed by Tim Shiel.
The game was released on Microsoft Windows, MacOS, Linux, Nintendo Switch, and PlayStation 4 consoles on 20 September 2018, on Xbox One on 29 November 2018., and for iOS devices on May 17, 2019.
Reception
The Gardens Between received "mixed or average" reviews for PS4, and "generally favorable" reviews for PC and Switch, according to the review aggregator Metacritic.
The Verge Michael Moore considered how The Gardens Between presented a type of theoretical physics related to different points-of-view when discussing the potential of time travel, as what Arina and Frendt would witness would be drastically different from what the player witnesses or other potential perspectives in the game.
The Gardens Between won the award for "Game of the Year" at the 2018 Australian Game Development Awards, and was nominated for "Australian Developed Game of the Year" at the Australian Games Awards. It was also nominated for "Gamer's Voice: Video Game" at the SXSW Gaming Awards, and won the award for "Puzzle Game" at the 2019 Webby Awards, whereas its other nomination was for "Best Art Direction". It was also nominated for "Best Audio/Visual Accomplishment" at the Pocket Gamer Mobile Games Awards.
References
External links
Category:2018 video games
Category:IOS games
Category:Linux games
Category:MacOS games
Category:Nintendo Switch games
Category:PlayStation 4 games
Category:Puzzle video games
Category:Video games developed in Australia
Category:Video games with time manipulation
Category:Windows games
Category:Xbox One games
Category:Unity (game engine) games
Category:Art gamesIntroduction {#Sec1}
============
Aspirin confers protection against myocardial infarction (MI), stroke, and other vascular events and reduces mortality for men and women with coronary heart disease (CHD).[@CR1] Although the utility of aspirin for the primary prevention of vascular events in otherwise healthy women is unclear,[@CR2]--[@CR4] strong evidence supports the benefits of aspirin for women with CHD.[@CR1],[@CR5] American College of Cardiology (ACC)/American Heart Association (AHA) guidelines therefore recommend daily aspirin for all patients with atherosclerotic cardiovascular disease unless contraindicated.[@CR5],[@CR6]
Gender differences in the management of acute coronary syndromes, including the use of thrombolytics, angioplasty, beta-blockers, and aspirin, are well documented.[@CR7]--[@CR13] Given aspirin's clear benefits for both women and men with CHD, gender differences in its use that persist beyond the inpatient experience could additionally impact the health of women with CHD on a population level. However, less is known about gender differences in outpatient care of CHD in general,[@CR14]--[@CR17] and few studies have specifically assessed gender differences in aspirin use among men and women with CHD.[@CR18],[@CR19]
Estimating aspirin use poses a special challenge. Aspirin's low cost, over-the-counter availability, and widely known benefits for patients with CHD distinguish it as a unique medication whose patterns of use are difficult to measure and may be less subject to mechanisms proposed to explain gender disparities in other medical treatments.[@CR11],[@CR16],[@CR20] For example, differences in prescription drug coverage are less likely to affect aspirin use. Consequently, gender differences in aspirin use may not correspond to those demonstrated for other aspects of care for CHD.
Most studies addressing gender differences in the outpatient care of patients with CHD were limited to local populations or particular health systems[@CR14],[@CR15],[@CR17],[@CR21],[@CR22] and others lacked outpatient measures of aspirin use.[@CR7],[@CR12],[@CR21] Two studies utilized national data but relied on ambulatory visit documentation that may not accurately measure aspirin use, and these were estimated per visit reporting rates rather than population prevalences.[@CR18],[@CR19] As a result, estimates of aspirin use vary widely, from 33%[@CR19] to 83%[@CR17] to 97%,[@CR15] and the significance of gender differences in the general population of patients with CHD remains unclear.
Therefore, to more clearly define population-level differences in aspirin use between women and men with CHD and to investigate patient characteristics that may contribute to or modify such differences, we used data from a nationally representative survey to compare self-reported aspirin use by gender in adults with CHD.
Subjects and Methods {#Sec2}
====================
Data Source {#Sec3}
-----------
We analyzed data from the 2000, 2001, and 2002 Medical Expenditure Panel Survey (MEPS), a survey sponsored by the Agency for Healthcare Research and Quality and the National Center for Health Statistics. MEPS is designed to provide nationally representative estimates of health care use, expenditures, sources of payment, and insurance coverage.[@CR23],[@CR24] Starting in 2000, condition-specific questions were included to assess whether care is consistent with practice guidelines.[@CR25] Each panel of respondents is drawn from the previous year's National Health Interview Survey, and respondents are repeatedly interviewed in person 5 times over a 2 1/2-year period using computer-assisted personal interviewing technology. Response rates for the three survey years varied between 64.7% and 66.3%.[@CR23] The MEPS survey design is complex, involving multistage sampling and producing stratified and clustered data. Information is provided to account for the complex survey design, including weights to adjust for nonresponse and disproportionate sampling. Each year of data provides a representative sample of the U.S. civilian noninstitutionalized population. MEPS has been used previously to study various issues relating to women's health, gender disparities, and cardiovascular disease.[@CR26]--[@CR28] Because this study used publicly available anonymous data, the Institutional Review Board of Brigham and Women's Hospital deemed it exempt from review.
Study Population {#Sec4}
----------------
Our study cohort included participants 40 years of age or older at the time of the survey who reported a diagnosis of coronary heart disease (CHD) or a previous heart attack or myocardial infarction (MI). Individuals with missing values for demographic or clinical variables were excluded.
Study Variables {#Sec5}
---------------
Aspirin use and covariates were ascertained from self-reports. Participants or their proxies were asked two questions to determine the presence of CHD: "Have you ever been told by a doctor or other health professional that you had \[coronary heart disease\]," or "\[a heart attack, also called myocardial infarction or MI\]?" Those who replied yes to either of these questions were asked, "Do you take aspirin everyday or every other day?" Respondents with MI or CHD who did not report regular aspirin use were asked, "Do you have a health problem or condition that makes taking aspirin unsafe?" Those who reported such a contraindication were specifically asked "Is that problem stomach-related or something else?" Neither the dose nor the duration of aspirin use was determined, and specific contraindications were not characterized beyond whether they were "stomach-related."
Demographic and socioeconomic covariates included age (at the time of the interview), gender, health insurance status (private insurance, public with no private insurance, or uninsured), education (\<high school education, high school graduate, or \>high school education), poverty category (income 0--124%, 125--199%, 200--399%, or 400+% of local poverty level adjusted for family size), and census region (
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] |
decidedly ex-Obama pastor Jeremiah Wright.
“You’re talking to the network…Obama White House remembers this… that broke the Jeremiah Wright tapes.”
The implication?
ABC News was Johnny-on-the-spot on the story of then-Senator Obama’s now infamous — and ex — pastor, the Reverend Jeremiah Wright. In March of 2008.
Remember that date. March — 2008. Here’s the link to the story, filed on March 13 by ABC’s Brian Ross
This remark came about in the course of a conversation with O’Reilly in which Sawyer, discussing the role of ABC News in the last presidential campaign, insisted that her network was not populated by liberals who tilted the news leftward. O’Reilly had cited a study from the Center for Media and Public Affairs on the network news coverage of the Obama-McCain campaign that showed the tilt in favorable coverage for Obama over McCain as follows:
Obama McCain
CBS 73% 31%
NBC 56% 16%
ABC 57% 42%
ABC had fared best of the three broadcast networks, but the point of liberal media bias — the kind of reporting that dates as far back as the 1960 Kennedy-Nixon campaign — stood. So O’Reilly persisted.
And out popped the above statement on Jeremiah Wright.
Let’s be clear here. Sawyer used the word “tapes” — and strictly speaking she is correct.
The problem comes with the context — in which she is clearly trying to imply that ABC was the proverbial dog with a bone in uncovering the relationship of Wright to his famous congregant, and what the implications might be for the country if a man who sat in Wright’s pews for 20 years listening to Wright’s leftist political rants were elected president.
Bluntly put — this is poppycock.
The man — and the network — that did the background research on this was, yes indeed, Sean Hannity and Fox News.
On February 28, 2007 — over a full year before ABC first aired its Wright story — Hannity had located columnist Erik Rush, who had written an article on Senator Obama and his church. He put Rush on the air that night.
The very next night, Hannity had managed to corral Wright himself on his Fox show with liberal Alan Colmes. Here’s the clip.
Out poured the tale of Wright’s devotion to Black Liberation Theology and the radical writings of James Cone and Dwight Hopkins. From this initial work the connections of Wright to Louis Farrakhan and Libya’s Colonel Muammar Qaddafi were uncovered and more.
And on it went.
The role of ABC News here?
Zip, nada, zero.
And yet plain as can be, there sits Diane Sawyer, the anchor of ABC News, on the set of Fox’s O’Reilly Factortrying to pretend ABC was a prime mover in Hannity’s story — a Fox story that surely would never have seen the light of day anywhere had it not been for Hannity’s tenacity in digging it out and putting it on TV. And, as regular viewers will recall, being snickered at while doing it — snickering that stopped when Obama finally felt so much pressure on Wright he stopped going to the church and felt the need to publicly rebuke the man he had once said was like an “uncle” to him.
Ms. Sawyer insisted her network would be providing “fantastic coverage” of the 2012 race, citing the liberal ex-Clinton aide George Stephanopoulos as a key member of her team.
If this is an example of the work to come from ABC News on the 2012 presidential campaign… well, we report, you decide.
BILL O’REILLY, HOST: In the “Back of the Book” segment tonight: As we reported last night, elements of the national liberal media have begun their campaign to re-elect President Obama. The attacks on Fox News are being stepped up, and we used an example of NBC News correspondent Andrea Mitchell deriding Israeli Prime Minister Benjamin Netanyahu for criticizing Mr. Obama.
Here now to talk about the Obama advantage in the media, Fox News political analyst Charles Krauthammer, who is in Washington this evening. So how much of an advantage? Because in my lifetime covering politics, 35 years now, I’ve never seen a media as rabidly invested in a president as the liberal national media is in Mr. Obama. Have you?
CHARLES KRAUTHAMMER, FOX NEWS CONTRIBUTOR: Well, I think that is true, and you can see it in a Pew study, Pew Center for Excellence in Journalism that they did in 2008 election. They found that of the three cable networks, Fox played it absolutely right down the middle, the same amount of favorability to McCain as to Obama. CNN three times as favorable to Obama as to McCain; MSNBC 5 to 1. So, I mean, and that was four years ago. Interesting, to give you an idea of how biased the media is, when it issued a press release on that study, Bill, it played it as CNN was the cable norm, with MSNBC on one side and Fox on the other deviating from the norm. The norm being the pro-Obama bias of CNN, rather than the norm that any objective American would say, which is what Fox has done, which was to play it right down the middle.
O’REILLY: Sure. Now, there was another study done by the Center for Media and Public Affairs that showed the network broadcasts — CBS, ABC and NBC — were 68 percent positive for Obama, Senator Obama, then-Senator Obama, 32 percent negative. For John McCain, it was the reverse: 36 positive, 64 negative. So, my contention is that nothing is going to change this time around. That the national TV media and the big urban newspapers, like The New York Times, the Los Angeles Times, The Washington Post, will all be trying to get President Obama re-elected. So the question then becomes: How much of an advantage is it for the president?
KRAUTHAMMER: Well, it’s a major advantage, but you’ve got to remember this. The left, the Democrats always have the press on their side. They’ve had it for 40 years. Nonetheless, the Republicans have won the presidency seven out of the last 11 elections, and that’s because what Republicans have, what conservatives have is the country, which is a center-right country, has remained so almost unchangingly for four decades. So what the media bias does is it slightly — it gives an advantage. It’s a major advantage, but it’s undoing the deficit that Democrats and liberals already have because it’s a country that is not essentially conducive to a liberal message.
And as bad as it appears to be with the tilt in favorable coverage for liberal Barack Obama for, well, somewhat less liberal John McCain – (and here is the result of the study again):
Obama McCain
CBS 73% 31%
NBC 56% 16%
ABC 57% 42%
– I believe it is actually FAR worse than that.
The reason I say that is there’s an implicit assumption that isn’t true; namely, that both John McCain and Barack Obama had exactly the same negative baggage or positive qualities. As an example, if Tom and Dick had pretty much the exact same record, and the press covered Dick more favorably than Tom, you’d certainly be able to show bias.
But what if Dick had a long history of radical associations, beginning with communist Frank Marshall Davis, and including racist un-American bigots such as Jeremiah Wright and terrorists such as William Ayers? What if Dick had all the political baggage of a Chicago thug, including dirty deals with criminal scumbags such as Tony Rezko? What if Dick’s wife had all KINDS of dirty baggage? What if Dick could be documented to have a radical history of being a communist? Just as a couple of examples? Would it be fair or legitimate to expect the coverage to be evenly “favorable” versus “unfavorable,” or would FAIR and OBJECTIVE coverage have skewed dramatically against Dick???
In the case of Barack Obama, the guy who deserved virtually ALL the negative coverage got virtually NONE. Versus war hero John McCain who should have received very little unfavorable coverage and got virutally nothing BUT???
And that same overwhelming media bias that got Obama an undeserved victory and the presidency in 2008 is just as biased today in defending the failure’s record.
One of the interesting things about the mainstream media’s wars on Fox is just how hypocritical the Fox News haters are.
As an example, Geraldine Ferraro passed away. Fox News spent the day honoring the first woman to truly break the ceiling in the modern political era. And although a famous liberal, Ferraro was a Fox News contributor. Because Fox News actually is fair and balanced. Roger Ailes personally honored Geraldine Ferraro as a woman who “made deep contributions on a number of significant issues.” Which is to say that Fox News shows a degree of class that is entirely lacking in the media dominated by the unbalanced and hysterical left.
When the mainstream media outlets hires Sarah Palin as a highly-respected contributor, come back and see me.
If you watch leftwing liberal hatchet organizations such as Media Matters, and then watch the mainstream news coverage, it is remarkable how often talking points that started with the KoolAid-
|
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] |
69 ± 0.03
*C. orbiculata* 50 0.09 ± 0.01 0.29 ± 0.01 0.34\* ± 0.01 0.41\* ± 0.07 0.50\* ± 0.02 0.53\* ± 0.01 0.61\* ± 0.04 0.59\* ± 0.05 0.58\* ± 0.03
100 0.08 ± 0.05 0.26\* ± 0.01 0.31\*\* ± 0.04 0.37\*\* ± 0.01 0.38^+^ ± 0.02 0.36^+^ ± 0.03 0.36^+^ ± 0.02 0.33^+^ ± 0.01 0.36^+^ ± 0.04
200 0.11 ± 0.03 0.22\* ± 0.02 0.26^+^ ± 0.01 0.27^+^ ± 0.01 0.28^+^ ± 0.04 0.31^+^ ± 0.02 0.30 ± 0.02 0.20^+^ ± 0.01 0.30^+^ ± 0.01
400 0.10 ± 0.04 0.19\* ± 0.02 0.22^+^ ± 0.01 0.21^+^ ± 0.03 0.21^+^ ± 0.02 0.20^+^ ± 0.04 0.22^+^ ± 0.01 0.19^+^ ± 0.01 0.19^+^ ± 0.02
Indomethacin 10 0.11 ± 0.02 0.14^+^ ± 0.02 0.18^+^ ± 0.04 0.20^+^ ± 0.06 0.19^+^ ± 0.03 0.18^+^ ± 0.01 0.17^+^ ± 0.02 0.16^+^ ± 0.03 0.15^+^ ± 0.04
DMSO 0.25 mL 0.11 ± 0.03 0.36 ± 0.06 0.44 ± 0.04 0.53 ± 0.07 0.64 ± 0.03 0.66 ± 0.04 0.70 ± 0.02 0.69 ± 0.03 0.67 ± 0.01
----------------- ------------- --------------- ----------------- ----------------- ---------------- ---------------- ---------------- ---------------- ---------------- ----------------
\**P* \< 0.05, \*\**P* \< 0.025, ^+^ *P* \< 0.001 versus physiological saline control, ANOVA (*n* = 8).
UR: untreated rats.
PS: physiological saline.
DMSO: dimethylsuloxide.
[^1]: Academic Editor: Esra Küpeli Akkol
Transverse verses midline incisions for abdominal surgery.
The choice of surgical incision in the abdomen is determined by access for surgery. It has been suggested that utilising a transverse or oblique rather than a midline incision may influence other parameters such as recovery and complication rates. However, there is little consensus in the literature as to whether a particular incision confers any advantage. To determine whether a midline incision or a transverse incision (including oblique incision) confers any recovery advantage to the patient. Search terms included randomised trials containing combinations of the following: 'abdominal', 'incisions', 'horizontal', 'transverse','vertical','midline', and 'laparotomy'. All prospective randomised trials comparing midline with transverse incisions for abdominal surgery were included. Caesarian sections were excluded. Two review authors assessed the methodological quality of potentially eligible trials and independently extracted data from the included trials. A wide range of outcome measures was considered. Due to differences in the method of assessment, the variability of data and the heterogeneity of the participant groups it was difficult to pool some of the outcome data. Despite these limitations, and potentially significant biases related to methodological quality, there was evidence to suggest that a transverse or oblique incision may be less painful and have less impact on pulmonary function than a midline incision, particularly in the early postoperative period. However, there was no difference seen in early or late postoperative complications between a transverse or oblique and a midline incision and recovery times were similar. Both analgesia use and pulmonary compromise may be reduced with a transverse or oblique incision but this does not seem to be significant clinically as complication rates and recovery times are the same as with midline incision. The methodological and clinical diversity and the potential for bias in the included studies also mean that the results in favour of a transverse or oblique incision, particularly with regard to analgesic use, should be treated with caution. The optimal incision for abdominal surgery still remains the preference of the surgeon. NOT RECOMMENDED FOR FULL-TEXT PUBLICATION
File Name: 15a0233n.06
Case No. 13-6315
UNITED STATES COURT OF APPEALS
FOR THE SIXTH CIRCUIT
FILED
PRIME FINISH, LLC, ) Mar 30, 2015
) DEBORAH S. HUNT, Clerk
Plaintiff, )
and ) ON APPEAL FROM THE UNITED
) STATES DISTRICT COURT FOR
CAMEO, LLC, ) THE EASTERN DISTRICT OF
) KENTUCKY
Intervening Plaintiff-Appellant, )
v. )
)
ITW DELTAR IPAC, )
)
Defendant-Appellee. )
)
)
)
)
BEFORE: BOGGS, SILER, and CLAY, Circuit Judges.
SILER, Circuit Judge. Intervening Plaintiff Cameo, LLC appeals the district court’s
dismissal of its action and denial of the subsequent Rule 60(b) motion. For the reasons stated
below, we REVERSE and REMAND for further proceedings.
FACTUAL AND PROCEDURAL BACKGROUND
I. Cameo’s Intervention and First Appeal to this Court
In 2008, Prime Finish, LLC filed suit against Defendant ITW Deltar IPAC (“ITW”) in
state court, alleging breach of a product-supply agreement between the two parties and claiming
Case No. 13-6315
Prime Finish v. ITW Deltar IPAC
compensatory damages and an early-termination penalty specified in the agreement. After the
case was removed to federal court, Cameo filed an intervening complaint alleging that the early-
termination penalty should be paid by ITW directly to Cameo.
The district court found that Cameo lacked standing to sue ITW and granted summary
judgment in favor of ITW.1 On appeal, this court ruled that Cameo had standing to sue as an
intended creditor beneficiary under the product-supply agreement. Prime Finish, LLC v. Cameo,
LLC, 487 F. App’x 956, 962 (6th Cir. 2012). We therefore reversed and remanded for further
proceedings. Id. at 963.
II. Cameo’s Failure to Comply with the District Court’s Orders on Remand
Although this court ruled that Cameo had standing to sue, we also found that “Prime
Finish retained the right to collect [the early-termination penalty], and ITW would not be
justified in paying Cameo directly.” Prime Finish, LLC v. Cameo, LLC, 487 F. App’x 956, 963
(6th Cir. 2012). In light of that ruling, and the fact that Cameo’s intervening complaint appeared
to rely on the notion that ITW should pay the penalty directly to Cameo, the district court
ordered on remand “that Cameo and ITW shall file, within fifteen days of the date of the entry of
this order, status reports addressing what claims, if any, still exist in this action, as well as a
proposal for their resolution, with suggested deadlines.”
ITW filed a timely status report arguing that Cameo lacked a viable claim on remand.
Cameo’s counsel, citing “irreconcilable differences” with Cameo, filed a motion to withdraw and
a motion for an extension of time while Cameo procured new counsel. On August 29, 2012, the
district court granted the motion for an extension. Cameo was given roughly twenty-six days to
obtain new counsel and fourteen additional days to file a status report. In a separate order
1
Shortly before the summary judgment ruling, the district court entered an agreed order dismissing all
claims between Prime Finish and ITW.
-2-
Case No. 13-6315
Prime Finish v. ITW Deltar IPAC
entered on August 30, the district court granted Cameo’s existing counsel leave to withdraw and
ordered future counsel to “enter their appearance and be prepared to cooperate in establishment
of a new scheduling order within 30 days after the date of this Order.”
C
|
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which is caused by ammonia from soiled bedding. Any rabbit living in those conditions is likely to have additional problems.
**DEFINITION**
A **rabbitry** is a place where domesticated rabbits are kept and typically bred.
After doing research and determining which breed is best for you, you'll want to be sure the rabbits you're getting will perform the way they're supposed to. A white rabbit may look like a New Zealand White but could end up being a different breed (or combination of breeds) that doesn't have the meat production qualities you're looking for.
It's advisable to spend a little extra money on rabbits who are pedigreed purebred, meaning their lineage is documented. Rabbits that are not pedigreed are considered to be crossbred, even though they may actually be purebred (but there's no way to prove it). Some rabbits are also registered, which means they've been examined by an official breed registrar and meet the breed standard. While these rabbits are clearly high quality, buying a registered rabbit would be more important for someone interested in entering rabbit shows or breeding rabbits for sale (as opposed to home meat or fiber production).
You can expect to pay anywhere from $15 to $40 for a good meat rabbit and around $50 to $60 for an Angora.
# **Rabbit Care**
Rabbits are lauded as being easy to care for and relatively trouble free, at least when compared to other livestock. That being said, there's a difference between tending to one rabbit as a pet and entering the realm of raising multiple rabbits. You will need to plan ahead and be sure you have adequate housing for your rabbits and their offspring, good equipment for feeding and watering, and methods for protecting your rabbits from predators and extreme temperatures. If you create the right conditions for your rabbits, they should stay happy and healthy.
**SMALL STEPS**
Rabbits have a reputation as the easiest food-producing animal to care for. They should be given food and fresh water each day, which takes just a couple of minutes per rabbit, and you'll spend a little time once a week to clean.
## **Housing**
Good rabbit housing needs to provide the following elements:
• Adequate space
• Ease in keeping clean
• Good ventilation but protected from drafts
• Shelter from temperature extremes and precipitation
• Protection from predators
Although there are many ways to keep rabbits, it's generally agreed that all-wire cages are the best way to achieve the necessary shelter goals. Any sort of hutch that uses wood as a building material is asking for trouble. The rabbit will gnaw the wood and soak it with urine and then it will rot. Any time the droppings are not able to fall through wire mesh (for example, in the corner of a wood frame), they will pile up and become difficult to clean.
It's best not to build cages out of chicken wire because it's easy for predators to tear through. The recommended material is 14-gauge galvanized wire mesh.
**SMALL STEPS**
If you construct a cage with wire mesh, be sure the smooth side is facing up when you construct the floor. This is much easier on the rabbit's feet and will prevent problems with sore hocks (the first joint, behind the foot) down the road.
The floor should be ½×1 inch, and the walls and ceiling can be 1×2 inches. A cage that is 36×36 inches and 18 inches high will do well for a doe and her babies.
Breeding does should not share a cage (although it's okay to put two does in a cage before they're bred as long as they get along), and your buck will need his own cage, so if you're starting with a trio of rabbits, you should plan on three cages. (See Appendix B for a resource with detailed instructions on building cages.)
Rabbits need to be sheltered from heat and precipitation, so the cages should be inside some sort of shelter. It's entirely possible to raise rabbits inside. Many wire cages come with a pull-out tray (which should be filled with straw or pine shavings) under the floor to catch droppings and urine, so the cages can be stacked if needed to save space. If you'd like to keep the cages outdoors, you can put them in a ventilated garage or shed.
Many experienced rabbit raisers prefer to suspend their wire cages from the ceiling (at a convenient height for the caregiver) rather than placing the cages on supports or on the ground. This makes it more difficult for predators and rodents to access the cages, and it prevents the aforementioned rotting that urine would cause to wood supports. If the cages don't have a pull-out tray beneath the floor, they should be suspended over straw so it will catch the droppings and urine.
Raising rabbits in cages may be unattractive to homesteaders, who are generally looking for "free-range" alternatives for their meat. Cage advocates say cages allow for selective breeding and better breeding outcomes, better predator protection, and no injuries due to rabbit fights.
Other owners raise rabbits in open runs rather than cages. A run can be a secure building (like a shed) with good ventilation. It must be protected from digging—both the rabbits digging out and predators digging in—by securing wire mesh over the entire floor and then covering it with a thick layer of straw bedding. It's also possible to construct a moveable rabbit run (similar to a chicken run—see Chapter 11), as long as it has an attached shelter so the rabbits can get out of the sun or rain. It is not advisable to let your buck live in the run with the does.
Some people allow their rabbits to run loose in their homes. It isn't difficult to litter box–train a rabbit. They prefer to always go to the bathroom in the same place, so if you place some droppings in the litter box, they should begin using it from that point on. If you do let your rabbits roam in your home, you'll need to "rabbit-proof" your wiring with hard plastic tubing. Be aware that rabbits like to chew, so furniture legs are also at risk.
## **Raising Rabbits Without Land**
Rabbits are so commonly raised in wire cages, as previously mentioned, that it's completely feasible to keep them inside your home. Many rabbit owners like to stack their cages, so you can keep several rabbits with very little floor space.
Putting your rabbit cages on your balcony leaves them vulnerable to the elements, but you can do it if the balcony is on the north side of the building—and therefore won't get too hot—and if you hang tarps to protect the rabbits from the elements.
If you want, you can use some of the ideas discussed in Chapters 11 and 12 to raise your rabbits on someone else's land, but it would be much simpler to just keep your rabbits indoors.
## **Food and Water**
Rabbits are herbivores, but that doesn't mean they can eat any and all kinds of vegetables. Rabbits have sensitive systems (more so than chickens or goats) and should be fed with care. They need to have feed that provides them with roughage, protein, vitamins, and minerals. The best way to ensure a balanced diet for your rabbits is to feed them pellets that have been specially formulated for them.
Some people do make their own rabbit feed from scratch or forage/grow items to give to the rabbits. It may seem more economical than purchasing pellets at first, but over the long term, the rabbits will be much healthier due to the balanced nutrition from the pellets, and that will end up saving you money.
Rabbits also enjoy a mineral salt block in their hutch. This not only provides them with extra nutrients they need, but it gives them something to chew on.
It's okay to occasionally give rabbits "treats" from your garden or table, but be sure to introduce any new foods slowly. Rabbits can have small amounts of the following items:
• Corn (and corn stalks)
• Sunflower and pumpkin seeds
• Roots and greens of carrots, turnips, and beets
• Dark leafy greens
• Dried bean or pea vines
• Bread
• Apple and banana peels
• Alfalfa hay
• Dandelions and clover (except sweet clover)
**ROAD BLOCK**
Rabbits should not be fed any greens that have been sprayed with pesticide. Also, cabbage should not be given to rabbits.
The best way to give rabbits their pellets is to purchase a feeder that can be attached to the wire cage. Many of these feeders can be filled from the outside (without opening the cage), which makes feeding time easier for you. You can place the rabbit food in a bowl if you'd prefer, but rabbits tend to turn over bowls and waste food when it's given to them that way.
An adult rabbit who's not pregnant or lactating should get around 6 ounces of pellets each day. Pregnant or nursing does, and growing youngsters, should receive more than that. You'll get a sense for how much to feed your rabbits with experience. They should be fed once a day on a consistent schedule. The rabbits should be excited (but not frantic) to see you at feeding time, and they should eat all the pellets you give them. If food is regularly left over the following day, you're feeding too much.
You can use the time when your
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] |
always a bad sign. You should want the actual person, not to be in love with some amorphous idea.
The one-on-one date starts and Ben brings his dog Scotch. If that dog has any instincts, it will whimper and hide from Courtney. Every girl in this house is wearing knee-high boots and shorts on her date.
And it's the season's first picnic! Courtney says she hasn't been asked out in a while. I think that's because, when you're doing coke at a club with whatever dude has bottle service, it's not officially a date.
She is pretty though. Her hand is on his knee. He says he has his career and is just looking for someone to share his life with and that she probably feels the same way. Yes. Courtney would like to model for the rest of her life. Or at least until she's a 34-year-old cougar like Blakely. Then she can just kill herself cause she's so damn old.
Ben loves Courtney and she is doing a good performance of normal, but mostly I think he's blinded by the fact that she's hotter than him. Ben asks, "Is this too good to be true?" Yes, Ben. It is. He parties hard and now he is growing up blah, blah, blah. I think she's bored out of her mind, but pretending to be interested. All I can think about is how, even if he picked her, one day he will watch this show and see her say to Kacie B., "How does that taste coming out of your mouth?"
At the end, she poses with her rose in front of camera and cackle — no joke. She's so doing this for her "career."
Time for the cocktail party and OMG his hair looks SO deeply bad! Lindzi tries to sell him on her being a farm girl. Blakely — who is safe this week — breaks up Samantha's one-on-one time and she's pissed. Apparently, they call Blakley, JUGS.
OMG — This has gotten looooong. Let me sum it up: Jenna is crying again. They blame Blakely. It has nothing to do with JUGS, but what can you do? She's the scapegoat and then she's crying. Ben finds her and tells her to "collect herself." Was that supposed to make her feel BETTER? OMG — everyone is crying. Jenna is under the covers on a bed!!!
Rose ceremony time: Crazy Jenna and the girl with the skunk hair go home. I think it's a good thing. Jenna needs to get home and find a psychiatrist STAT. See you next week (cause I'm a model …) when someone either passes our or dies during the rose ceremony.
Honestly, I don’t think Courtney is that awful. Well….maybe she is, but take a look at the moments beeetwn her and Ben and you can totally see why he’s keeping her there. She lets her guard down with him and is able to be quirky, fearless and fun. She picks up tarantulas, names them, and make him laugh by throwing him off-guard with silly comments. He’s having fun with her, and she’s really creating those moments of fun. He does need to further investigate her though – a girl with NO girlfriends probably has insecurity issues, she clearly needs a lot of attention and doesn’t handle herself well when her position is tested. This could end up being a classic case of a borderline geeky/shy dude latching on to the first pretty girl who gives him (too much) attention. If it all goes in the pooper he’ll have more confidence with how to handle women, but with a clearer head on his shoulders.El semen español, en general, está de capa caída. Yendo luego al meollo, al núcleo de la cosa, se puede apreciar que no en todas partes el espermatozoide patrio subsiste aquejado de la misma decadencia. Como en otros ámbitos, algunas regiones suben la media, y otras la hunden notablemente. Aquí lo que importa no es el tamaño del envoltorio, sino la calidad de lo que alberga en su interior. Y por lo menos en España, en este sentido, hace tiempo que no podemos presumir de ello. Se trata de un hecho irrefutable demostrado por diversos institutos científicos de todo el país. Y hay algunas regiones de nuestra geografía en los que este problema se ve más agravado que en otras.
Un estudio reciente de la oficina estadística comunitaria Eurostat advierte de lo que venía tiempo fraguándose: España es el segundo país de la Unión Europea con la tasa de fertilidad más baja. Esto no tiene que ver exclusivamente con la (cada vez menos) multitudinaria y minúscula soldadesca masculina, pero guarda mucha relación. Y dentro de nuestro país hay una región en concreto que desgraciadamente se lleva la palma en este terreno: Murcia. Y dentro de Murcia, Cartagena.
A lo largo de los últimos diez años, el esperma de los españoles ha disminuido su calidad un 2% cada año. Se trata de una auténtica crisis que delata que no todo va tan bien como parece. Y quizá por eso los últimos datos de Europa resultan tan inquietantes para nuestros pequeños espermatozoides.
Todo se reduce a unir los puntos. En la Región de Murcia hay una clínica de reproducción asistida por cada 86.000 habitantes. La aritmética puede resultar sencilla, pero rara vez arroja un dato anodino o intrascendente. En este caso podría parecerlo, pero todo apunta a que el semen de los murcianos y, en concreto, el que atesoran los hombres de Cartagena es el de peor calidad de toda España.
Imagen aérea de Cartagena y su litoral.
Ante un problema así resulta preciso encontrar soluciones. Quizá por eso tan solo en Murcia hay aproximadamente una quincena de centros de reproducción. Solo en Cartagena, donde viven 250.000 personas, hay cuatro. Una proporción, consideran voces experimentadas en el análisis del semen y en el sector, ciertamente elevada. En Murcia ciudad, que tampoco se queda atrás en esta problemática, uno puede toparse con hasta diez clínicas diferentes de fertilidad.
En Murcia habrá calidad en otros aspectos, pero en cuanto al semen, lo que se advierte es que esta brilla por su ausencia. Y la contaminación, los pesticidas de la archiconocida huerta y otros factores relacionados con la industria en la zona parecen ser la explicación al enigma de la caída del espermatozoide cartaginés.
Un problema dominante
El día a día de la ginecóloga Carolina Tovar transcurre casi siempre entre los microscopios del laboratorio y las entrevistas de la consulta. Su trabajo consiste en levantarse cada mañana con un objetivo: buscar respuestas a lo que parece un misterio pero no lo es: por qué en Murcia, y en concreto, en Cartagena, la calidad de los espermatozoides de sus habitantes es tan baja.
Se trata de una de las mayores expertas de la materia en el país. Lleva cinco años y medio trabajando en el Instituto Bernabéu de Cartagena, una suerte de laboratorio que parece por fuera una nave espacial y que está ubicado a 20 minutos andando desde el puerto de Cartagena, muy cerca del museo naval de la ciudad y de los majestuosos vestigios del teatro romano de la ciudad.
"Es una cosa seria", dice a EL ESPAÑOL. "Y nos llama la atención el modo en que ha pasado a ser un problema dominante. Anteriormente, la proporción de parejas que acudían en toda la región de Murcia era mucho menor. En los últimos diez años, quienes acuden a nosotros aquí por problemas de fertilidad les hacemos un estudio. El resultado: el 70 por ciento de los que acuden a nosotros tienen algún parámetro alterado. Y la mayoría son de Cartagena".
La ginecóloga Carolina Tovar lleva años analizando el semen de los españoles.
El centro Bernabéu abrió en Cartagena en el año 2003.
|
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] |
] recognized the Brown Siltstone Beds in Nebraska as stratigraphically correlative to the Sharps Formation in South Dakota. Later work [@pone.0047759-LaGarry1] has supported this correlation. The Brown Siltstone Beds occur stratigraphically below the Gering Formation and above the Whitney Member of the Brule Formation. In some areas of Nebraska, the Gering Formation disconformably overlies the Whitney Member of the Brule Formation [@pone.0047759-Darton1], [@pone.0047759-Tedford1] with no intervening Brown Siltstone Beds ([Figure 2](#pone-0047759-g002){ref-type="fig"}).
Results and Discussion {#s3}
======================
Regional Relationships {#s3a}
----------------------
Although the Gering and Sharps Formations, and the Brown Siltstone Beds share a stratigraphic position immediately above the Brule Formation, they are not all of similar lithology. The Gering Formation is principally a sandstone [@pone.0047759-Darton1], [@pone.0047759-Tedford1], whereas the Sharps Formation [@pone.0047759-Harksen1] and Brown Siltstone Beds [@pone.0047759-LaGarry1] consist mainly of siltstones. Unfortunately there is no surface lateral continuity of the Gering Formation or Brown Siltstone Beds of Nebraska with the Sharps Formation of South Dakota as the regions were separated by the Chadron Arch, a regional structural feature trending NW-SE and oblique to the Nebraska-South Dakota state line [@pone.0047759-Swinehart1]. However, the physical resemblances of the Brown Siltstone Beds and the Sharps Formation on each side of the arch suggest a similar source and well logs across the arch support this subsurface correlation [@pone.0047759-Swinehart1].
The Brule Formation upward through the Gering Formation deposits in Nebraska correlate lithologically and paleomagnetically with rocks in South Dakota from Brule Formation upward through the Sharps Formation.
In Nebraska the Whitney Member of the Brule Formation is about 300 feet thick and consists of nodular volcaniclastic siltstone with local channel sandstones and mudstones [@pone.0047759-Tedford1] conformably overlying the Orella Member of the lower Brule Formation. Similarly in South Dakota, the Poleslide Member of the Brule Formation consisting of nodular volcaniclastic siltstone with local sandstones and mudstones is of similar thickness [@pone.0047759-Harksen2], and conformably overlies the Scenic Member of the Brule Formation. Magnetic polarity Chron C12R is contained within the Whitney Member of the Brule Formation and the Poleslide Member of the Brule Formation [@pone.0047759-Swisher1].
Revised Stratigraphy {#s3b}
--------------------
Both the Poleslide Member of the Brule Formation in South Dakota and the Whitney Member of the Brule Formation in Nebraska are overlain conformably by lithologic bodies of approximately the same thickness: the Sharps Formation and the Brown Siltstone Beds [@pone.0047759-Harksen1], [@pone.0047759-Tedford1]. In the vicinity of the Chadron Arch, a thick tephra is identified at the base of both: the Rockyford Ash Zone (RAZ) in South Dakota [@pone.0047759-Nicknish1] and the Nonpareil Ash Zone (NPAZ) in Nebraska [@pone.0047759-Tedford1]. The lower portions of the Brown Siltstone Beds and Sharps Formation are more stratified than their upper portions. The upper portions of each are massively bedded siltstone with intermittent, vertically oriented, spindle/potato-shaped nodules. The lithologies of the Brown Siltstone Beds and the Sharps Formation are similar.
These data are consistent with the subsurface evidence of lateral continuity across the Chadron Arch [@pone.0047759-Swinehart1]. The Nonpareil Ash Zone (NPAZ) of the Brown Siltstone Beds can be traced in the subsurface across the Chadron Arch. This ash complex northeast of the Chadron Arch is known as the Rockyford Ash Zone (RAZ) [@pone.0047759-Nicknish1]. Swinehart, *et al.* (1985) provides direct subsurface evidence of the correlation of the NPAZ with the RAZ and the subsequent correlation of the Sharps Formation with the Brown Siltstone Beds.
Further confirmation of this correlation is provided by paleomagnetic data [@pone.0047759-Prothero1], [@pone.0047759-Prothero2]. Both the NPAZ and the RAZ were deposited near the base of magnetic polarity Chron C11N.
At the southernmost extension of the Brown Siltstone Beds in Nebraska, these beds are quite thin and overlain by 200+ feet of the Gering Formation. The Brown Siltstone Beds are thicker northward. At the Round Top to Adelia section a complete section of the Gering Formation displays a basal disconformity with the underlying Whitney Member of the Brule Formation. There is evidence of an Upper Whitney Ash (UWA) and an Upper Ashy Zone (UAZ). Proceeding to the northeast, the Gering Formation pinches out, the Whitney ash beds disappear, and the NPAZ appears at the base of the Brown Siltstone Beds [@pone.0047759-Tedford1] so that in the vicinity of the Chadron Arch and the town of White Clay, Nebraska, there is a fully developed section of the Brown Siltstone Beds with no overlying Gering Formation and no Whitney ashes ([Figure 3](#pone-0047759-g003){ref-type="fig"}). The NPAZ is a stratigraphic correlative of the RAZ, and the Brown Siltstone Beds in Nebraska occupy a position between the top of the Brule Formation and the Monroe Creek Formation identical to the Sharps Formation in South Dakota. Where the Gering Formation occurs in Nebraska, it disconformably overlies either Brule Formation sediments or the Brown Siltstone Beds. The Gering sediments are a stratigraphic equivalent, of a part of the upper Sharps Formation [@pone.0047759-Swinehart1]. All of the evidence indicates the Brown Siltstone Beds are strongly associated with the Sharps Formation and the Nonpareil Ash Zone within the Brown Siltstone Beds is an extension of the Rockyford Ash Zone.
![Stratigraphic Correlation of Sediments.\
At the southernmost extension of the Brown Siltstone Beds in Nebraska, these beds are quite thin and overlain by 200+ feet of the Gering Formation. The Brown Siltstone Beds are thicker northward. At the Round Top to Adelia section a complete section of the Gering Formation displays a basal disconformity with the underlying Whitney Member of the Brule Formation. There is evidence of an Upper Whitney Ash (UWA) and an Upper Ashy Zone (UAZ). Proceeding to the northeast, the Gering Formation pinches out, the Whitney ash beds disappear, and the NPAZ appears at the base of the Brown Siltstone [@pone.0047759-Tedford1] so that in the vicinity of the Chadron Arch and the town of White Clay, Nebraska, there is a fully developed section of the Brown Siltstone Beds with no overlying Gering Formation and no Whitney ashes. The NPAZ is a stratigraphic correlative of the RAZ, and the Brown Siltstone Beds in Nebraska occupy a position between the top of the Brule Formation and the Monroe Creek Formation identical to the Sharps Formation in South Dakota. Where the Gering Formation occurs in Nebraska, it disconformably overlies either Brule Formation sediments or the Brown Siltstone Beds. The Gering sediments are a stratigraphic equivalent, of a part of the upper Sharps Formation [@pone.0047759-Swinehart1] All of the evidence indicates the Brown Siltstone Beds are strongly associated with the Sharps Formation and the Nonpareil Ash Zone within the Brown Siltstone Beds is an extension of the Rockyford Ash Zone.](pone.0047759.g003){#pone-0047759-g003}
At the lower type section of the Sharps Formation, the Rockyford Ash immediately overlies sediments that weather similarly to Brule lithology. Ten miles north, at the type section of the Rockyford Member of the Sharps Formation is a single, thicker reworked ash layer with interbedded cut and fill structures slightly above Brule Formation sediments.
Twelve miles south of the Rockyford Member type section and five miles west of the lower type section of the Sharps Formation in the Grass Creek drainage system, there are two distinct ash layers at the base of the Sharps Formation separated by 31 feet. This corresponds to the stratigraphic position of the NPAZ of the Brown Siltstone Beds 20 miles south, in Nebraska, and to the RAZ at the lower type section of the Sharps Formation, and the ash layer on Sheep Mountain at the type section for the Rockyford Member of the Sharps Formation.
Between the upper portions of the Poleslide Member of the Brule Formation and the lower part of the Sharps Formation are massive siltstone deposits of
|
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] |
previously held that where a right of such fundamental importance as the right to life or the prohibition against ill-treatment is at stake, Article 13 requires, in addition to the payment of compensation where appropriate, a thorough and effective investigation capable of leading to the identification and punishment of those responsible, including effective access for the complainant to the investigation procedure (see Kaya v. Turkey, judgment of 19 February 1998, Reports 1998-I, pp. 330-331, § 107). Furthermore, in the case of a breach of Articles 2 and 3 of the Convention, which rank as the most fundamental provisions of the Convention, compensation for non-pecuniary damage flowing from the breach should in principle be part of the range of available remedies (Z and Others v. the United Kingdom [GC], no. 29392/95, §§ 108-109, ECHR 2001‑V).
63. However, the effectiveness of a remedy for the purposes of Article 13 does not depend on the certainty of a favourable outcome for the applicant (see Vilvarajah and Others v. the United Kingdom, judgment of 30 October 1991, Series A no. 215, p. 39, § 122).
64. In the instant case, the Court notes that the authorities were prepared to treat the applicant’s allegations seriously and not to dismiss them outright. It is to be observed in this connection that three prosecution instances examined his complaints. Furthermore, the prosecuting authorities agreed to re-open the investigation at the request of the NEKI.
65. During these investigations, the applicant was questioned as to his version of the events which had occurred in the police station. The suspected police officers were also questioned in the course of the investigations, including in the presence of the applicant in the context of a confrontation. Moreover, the applicant’s companions and the police officers on duty at the relevant time were heard as witnesses.
The investigators also appointed a medical expert to clarify the nature and possible cause of the applicant’s injury, and had regard to the medical report commissioned by the NEKI.
66. It is to be noted that the criminal proceedings were ultimately closed for want of sufficient proof that the applicant’s ear injury was caused by the suspected police officers.
For its part, the Court is satisfied that the investigations conducted were thorough and capable of leading to the identification and punishment of any State agent found to be responsible in the light of the evidence gathered (compare and contrast, for example, Labita v. Italy [GC], no. 26772/95, §§ 130-136, ECHR 2000-IV). Furthermore, it does not accept the applicant’s allegation that the prosecuting authorities did not discharge their duties in an independent and impartial manner.
67. Moreover, the Court does not consider it necessary to examine the effectiveness of the remedy contained in section 349 of the Civil Code, which the applicant was in any event prevented from pursuing because of his failure to lodge a timely complaint against the discontinuation order of 6 March 1996 (see paragraphs 21 and 26 above).
68. In these circumstances, the Court considers that the applicant had available to him an effective remedy in relation to his complaint under Article 3.
Consequently, there has been no violation of Article 13 of the Convention.
IV. ALLEGED VIOLATION OF ARTICLE 6 OF THE CONVENTION
69. The applicant claimed that he was denied effective access to a court, in breach of Article 6 § 1 of the Convention, which provides, inter alia:
“In the determination of his civil rights and obligations …, everyone is entitled to a fair and public hearing within a reasonable time by an independent and impartial tribunal established by law…”
70. The applicant submitted in particular that the decision of the prosecuting authorities not to indict the suspected police officers denied him access to a court in respect of a potential civil claim for damages. Since the criminal proceedings were discontinued, he could not take part in such proceedings as a civil party under section 55 § 1 of the Code of Criminal Procedure (see paragraph 25 above) in order to claim compensation. Moreover, although it would in theory have been possible for him to bring an action for compensation under section 339 of the Civil Code, since the damage in question arose out of an alleged criminal act, a civil court might, under section 152 § 1 of the Code of Civil Procedure (see paragraph 27 above), have stayed any such action until the issue of criminal liability had been determined. In sum, it is arguable that, in the circumstances, no civil action could have been brought in the absence of a criminal indictment arising out of the same facts.
71. The Government recalled at the outset that Article 6 does not guarantee a right to institute criminal proceedings against third parties, even if they are State agents (see Chizhov v. Ukraine, no. 6962/02, 6 May 2003). Therefore, access to court must be guaranteed only in respect of civil claims arising out of alleged ill-treatment. In the instant case, the applicant could have brought an action for damages under section 339 or an official liability action under section 349 of the Civil Code (see paragraph 26 above).
In the latter case, a pre-condition of access to a court would have been the exhaustion of ordinary legal remedies. A complaint under section 148 of the Code of Criminal Procedure against an order to discontinue investigations (see paragraph 25 above) is an ordinary legal remedy to be exhausted before any damages may be sought from the investigating authorities for their acts or omissions in the criminal proceedings. In the present case, the applicant failed to make timely use of this remedy and thereby lost the possibility of access to a court for the determination of his civil claims.
72. For the Court, any claim for damages brought by the applicant and based on alleged ill-treatment by the police would have involved “the determination of his civil rights”. Article 6 § 1 is, for that reason, applicable (see Assenov and Others v. Bulgaria, judgment of 28 October 1998, Reports 1998‑VIII, p. 3292, § 110).
The Court further notes that the applicant does not deny that section 339 of the Civil Code provided him with a cause of action which would have enabled him to commence proceedings in the civil courts. He contends, however, that any such action might have been stayed under section 152 § 1 of the Code of Civil Procedure.
In the latter respect, the Court observes that civil courts are entitled, rather than obliged, under section 152 § 1 to suspend their proceedings pending the outcome of criminal proceedings on preliminary issues. Furthermore, sections 3 § 5 and 4 § 1 of the Code of Civil Procedure (see paragraph 27 above) grant civil courts a wide margin of appreciation in selecting and evaluating evidence. Any possible uncertainty as to the application of the relevant rules of civil procedure could have been eliminated had the applicant availed himself of an action in damages. Since he failed to do so, his submissions concerning the possible outcome of such an action are a matter of speculation.
Furthermore, it is to be noted that it was the applicant’s own failure to file a timely section 148 complaint that appears to have barred his access to a court in respect of a possible official liability claim under section 349 of the Civil Code.
In these circumstances, it cannot be said that the applicant was denied access to a court or deprived of a fair hearing in the determination of his civil rights.
73. Consequently, there has been no violation of Article 6 of the Convention.
V. ALLEGED VIOLATION OF ARTICLE 14 OF THE CONVENTION
74. The applicant complained that his alleged ill-treatment and the subsequent proceedings conducted by the authorities showed that he was discriminated against on account of his ethnic origin, contrary to Article 14 read in conjunction with Articles 3 and 13 of the Convention.
Article 14 provides:
“The enjoyment of the rights and freedoms set forth in [the] Convention shall be secured without discrimination on any ground such as sex, race, colour, language, religion, political or other opinion, national or social origin, association with a national minority, property, birth or other status.”
75. The applicant submitted that the suspected police officers were aware of the fact that he was of Roma origin. He stated that the Hungarian police’s discriminatory conduct vis-à-vis persons of Roma origin was well-documented. He quoted a police officer telling him when he was leaving the police station: “Tell the Miskolc gypsies that they had better not set foot in Orosháza”.
76. The Government pointed out, as a preliminary objection, that the applicant had not exhausted domestic remedies as required by Article 35 § 1 of the Convention, since he did not complain in the domestic proceedings that his alleged ill-treatment was motivated by his ethnic origin. The allegation of a possible racist motive was not raised in his complaint against the decision of 30 November 1995, neither was the point mentioned in the complaint submitted by the NEKI in August 1998.
77. Furthermore, the applicant’s assertion that the police officers interrogating him were aware of his ethnic origin, and that their conduct was based on this, was devoid of any proof. The Government observed that the applicant’s arguments in this connection relied only on statements about the alleged existence of prejudice against the Roma within Hungarian society in general and the police in particular. However, for the Government, such general considerations could not justify a conclusion that the applicant was discriminated against by the police on the ground of his ethnic origin. In such cases, proof “beyond reasonable doubt” was required, which may follow from the coexistence of sufficiently strong, clear and concordant inferences or of similar unrebutted presumptions of fact (see Velikova v. Bulgaria, no. 41488/98, ECHR 2000‑VI; Anguelova v. Bulgaria, no. 38361/
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that would not have time to ripen before it froze. The house was full of the syrupy scent of preserves and the spicy odor of pickles.”We will take our provisions with us when we move to town this time,” said Pa with satisfaction. “And we must go soon. I don’t want another October blizzard to catch us in this thin-walled little house.”
“This winter isn’t going to be as hard as last winter,” Laura said. “The weather doesn’t feel the same.”
“No,” Pa agreed. “It isn’t likely this winter will be as hard, nor come as soon, but this time I intend to be ready for it when it does come.” He hauled the oat straw and the corn fodder and stacked them near his haystacks in town. He hauled the potatoes and turnips, beets and carrots, and stored them in the cellar of his store building. Then busily all one Monday evening and far into the night, Laura and Carrie helped Ma pack clothes and dishes and books.
Whatever temperatures autumn brings to your part of the world, I hope you’ll join me in marking the change of season. What’s your favorite description of autumn?A description of the october revolution led by the bolsheviks under leadership of vladimir lenin and
Russian revolution of 1917 involved the collapse of an empire under tsar nicholas ii and the rise of marxian socialism under lenin and his bolsheviks october. October revolution that brought the bolsheviks to power and ushered in communism under the leadership of vladimir lenin vladimir lenin led. Was lenins leadership the main ewas lenin's leadership the main reason for bolshevik on 24th october 1917 the lenin and the bolsheviks led a revolution. Most russians had lost faith in the failed leadership october revolution), leftist revolutionaries led by bolshevik party leader vladimir lenin.
Bolshevik was founded by vladimir lenin assisted by alexander bogdanov under martov’s leadership, the mensheviks were born october revolution. Who was lenin he led the workers of the and socialist revolutions under the leadership of bolsheviks the russian revolution has had all. The october bolshevik revolution of 1917 to what extent did the october revolution of 1917 (the bolshevik the bolshevik revolution (led by lenin. The role of bolshevik leaders in the red army of workers' and peasants' defense under the direction of vladimir lenin (though the bolshevik leadership's.
Lenin's leadership was the main reason why the bolsheviks were under the leadership of vladimir lenin managed to the october revolution. Vladimir ilyich lenin he didn't believe that the revolution should be under the leadership of beaurocrats the bolsheviks were led by lenin.
Vladimir lenin, also called vladimir ilich lenin under the leadership of were the natural allies of the bolshevik revolution thus lenin’s revolutionary. Lenin and the bolshevik revoloution essayevaluate lenin’s contribution to the success of the bolshevik revolution in november 1917 lenin.
Higher history on the causes of the october revolution in russia: bolsheviks formed and led by the vladimir to october gcse: life in lenin's. The russian revolution in october 1917, 1 led by the bolshevik party of vladimir lenin, is the most important event in history for revolutionary socialists for the first time, a revolution led by the working class won power in an entire country and began attempting to construct a socialist society based on the ideas of workers’ control and. Kids learn about the biography of vladimir lenin he led the bolshevik revolution that put millions of russian soldiers were killed under the leadership of. However, most significant is that even bolshevik leaders like trotsky, who in principle shared lenin’s fundamental theoretical assumptions regarding the necessity and feasibility of an early socialist revolution in russia, were skeptical of mobilizing workers, soldiers, and sailors behind the “immediate bayonet charge” insisted on by lenin.
A description of the october revolution led by the bolsheviks under leadership of vladimir lenin and
On nov 7, 1917, russia’s bolshevik revolution took place as forces led by vladimir ilyich lenin overthrew the provisional government of alexander kerensky the provisional government came to power after the february revolution resulted in the russian monarchy being overthrown in march 1917. October 1917: the bolsheviks take power were overwhelmingly bolsheviks the october revolution was to be no “putsch” by a under trotsky’s leadership. Red century from the 'october revolution' in 1917 led by vladimir lenin the bolsheviks established what became the union of soviet socialist republics.
“it first sprang into prominence in the early days of the revolution under the leadership of vladimir lenin history: 1917 the bolsheviks seize power in. The russian revolution — part 1: from almost at the same time as the october revolution led by the great lenin and although under the leadership of. The october revolution, in which the bolshevik party, led by vladimir lenin, and the workers' soviets, overthrew the provisional government while many notable historical events occurred in moscow and st petersburg, t was also a broadly based movement in cities throughout the country, among national minorities throughout the empire, in the.
On april 7, the bolshevik newspaper pravdapublished the ideas contained in lenin’s speeches, which collectively came to be known as the april theses from the moment of his return through late october 1917, lenin worked for a single goal: to place russia under bolshevik control as quickly as possible. Worker support for the bolshevik’s october revolution from the beginning vladimir lenin government and gain support for his bolshevik-led socialist revolution. The october revolution led by the bolsheviks, demonstrated under banners reading an assault led by vladimir lenin was launched at 9:45 pm signaled by a.
Download a description of the october revolution led by the bolsheviks under leadership of vladimir lenin and:MENTAL JAMMING
Mental jamming Thinking about or performing too many tasks at a time leads to forgetting of things. A professor of cognitive science and neurology makes it a point that the entry to retention of things in memory is attention. Multitasking makes it hard to commit things to memory in the first place. Attention is the gateway to retention says a professor of neurology and cognitive science. If the information doesnt get in to begin with forget trying to save it and access it later. If your day is filled with multiple activities dont rely on your recall skills. The old proverb The worst pencil is better than the best memory still h9olds true. So make lists and take notes. And ask others to do the same. For instance, if your children complain of your forgetting things then tell them that if they really want you to do something they should write it on a paper and paste it on your dressing table or put it in your purse. Interestingly people tend to blame age rather than busy-ness for their memory slips - and then may think their memory is worse than it really is. Take the common lapse of forgetting someones name. It happens to everybody young and old. Names are difficult to handle because theyre abstract. The persons face and his name arent logical ideas for the brain to link together. And the older we get the more data we have to sort through. Some mental lapses are due to congestion, says doctor who compares the middle aged brain to a bridge at rush hour. When you have too many cars and too few lances nothings can move. One of the reasons we blank out names he explains is that we know too many of them. Anxiety makes it worse by creating more traffic. Thats why the name often pops into your mind later says doctor when the mental traffic has died down. Could it be an illness? Certain medical problems can interfere with your ability to recall. If youre struggling see a doctor to rule out such possible causes as: Hypothyroidism (under active thyroid gland) slows down information processing; Hyperthyroidism (overactive thyroid gland) can cause distracting physical sensations such as itching which make it hard to concentrate. Mood disorders affect attention and concentration so you dont form strong enough memories to start with. Head injury even a mild blow to the head can lead to memory problems later on. Hypertension can cut down the blood flow to the brain. Blood sugar fluctuations can also interfere with attention. Sleeping pills antihistamines And anti-anxiety medications are some other culprits for poor memory and forgetfulness.The popular BitTorrent site Mininova celebrates its 3rd anniversary today. At the time it launched, no one would have predicted that it would become the success story it turned out to be, but we can now safely say that Mininova is here to stay.
There was quite a bit of news surrounding Mininova in the last year, they regained the.com domain, served
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342
] |
Stahl, through their disciplined lack of mastication, have given their colleagues something toothsome to think about.
Crandall, Brian D., and Peter W. Stahl (1995). 'Human Digestive Effects on a Micromammalian Skeleton.' Journal of Archaeological Science 22 (6): 789–97.
##### May We Recommend
##### 'Pharyngeal Irritation After Eating Cooked Tarantula'
by Stephen J. Traub, Robert S. Hoffman, and Lewis S. Nelson (published in the Internet Journal of Medical Toxicology, 2001)
### The Water Test
The study 'Similar Preference for Natural Mineral Water between Female College Students and Rats' pulls off a nice bit of interspecies diplomacy. Reading it end to end, you would be hard pressed to say who – the women or the rats – was most intended to benefit from the research.
Written by Esumi Yukiko of Shimane Women's Junior College in Matsui, Japan, and Ohara Ikuo of Kobe Women's University, and published in the Journal of Home Economics of Japan, this six-page monograph describes an apparently straightforward experiment.
The authors explain that their work was partly inspired by a simple fact: 'The Society for the Study of Tasty Water, which is sponsored by the Ministry of Public Welfare, proposed hardness to be one of the most important requirements for tasty water.' Therefore, they say, 'The objectives of this study are to investigate the best mineral water for drinking by using hardness as an index, and whether the response of rats to mineral water can be extrapolated to that of humans.'
Yukiko and Ikuo conducted taste tests with sixteen healthy female humans, sixteen healthy female rats, and fourteen different brands (nine Japanese, two Belgian, and two French) of bottled water. The water, all of it, was uncarbonated. For good measure, the taste testers also taste-tested tap water.
The women drank from cups, the rats from objects called 'drinking tubes'. The report specifies that the rats each weighed 160 grams, give or take three grams, and were 'housed individually'. We are told nothing, not a blessed iota of fact, about the weight of the women, or about their living arrangements. The report also specifies that 'Before beginning the experiment, each animal was fed on a commercial stock diet', but says nothing about what the women consumed.
Yukiko and Ikuo reached two main conclusions. First, they write, 'appropriate levels of minerals are needed for tasty drinking water, too little being as bad as too much, with around 58.3 milligrams/liter of hardness being most favorable'. Second, and perhaps more memorably: 'The present study has demonstrated that the preference for different types of natural mineral water by female college students was similar to that by rats.'
Yukiko and Ikuo make no claim that theirs is the final word. For one thing, they point out, 'The menstrual cycle of the subjects was not considered in this experiment, although taste sensitivity can be influenced by it.'
'Similar Preference for Natural Mineral Water between Female College Students and Rats' is not the only research study to proudly, explicity comparison-test college students and rats. But it may be the most exuberant since C. Lathan and P. E. Fields's 1936 tell-all 'A Report on the Test-retest Performances of 38 College Students and 27 White Rats on the Identical 25 Choice Elevated Maze'.
Yukiko, Esumi, and Ohara Ikuo (1999). 'Similar Preference for Natural Mineral Water between Female College Students and Rats.' Journal of Home Economics of Japan 50 (12): 1217–22.
Lathan, C., and P. E. Fields (1936). 'A Report on the Test-retest Performances of 38 College Students and 27 White Rats on the Identical 25 Choice Elevated Maze.' Journal of Genetic Psychology 49: 283–96.
### Eggs Allsorts, Birdflesh Everykind
Which birds are the most edible, and which are the least? During and just after World War II, Hugh B. Cott of the University of Cambridge doggedly pursued these questions, using means that were waspy, feline, and human. His discoveries are summed up in a 154-page report entitled 'The Edibility of Birds – Illustrated by 5 Years Experiments and Observations (1941–1946) on the Food Preferences of the Hornet, Cat and Man'.
In October 1941, Cott made a chance observation. While collecting and preserving bird skins in Beni Suef, Egypt, he discarded the meaty parts of a palm dove (Streptopelia senegalensis aegyptiaca) and a pied kingfisher (Ceryle rudis rudis). Hornets descended upon the palm dove carcass, but ignored the kingfisher.
Cott, entranced, later offered other hornets a choice of different cuts (breast, wings, legs, and gut) of some forty different bird meats, in 141 experiments conducted in Beni Suef, Cairo, and Tripoli, Lebanon.
The hornets especially took to crested lark, greenfinch, white-vented bulbul, and house sparrow. They voted (metaphorically) thumbs down on golden oriole, hooded chat, masked shrike, and hoopoe, among others.
Cott conducted another forty-eight experiments, with nineteen kinds of bird meat, using three cats (two in Cairo, one in Tripoli) as tasters. In each experiment, the taster chose (or chose not to choose) between two different bird meats.
To answer the 'which would a human eat' question, Cott gathered data 'from natives in the Lebanon; from personal experience and from observations sent in reply to a published inquiry; and from the [scientific] literature'. He drew most heavily from Reverend H. A. Macpherson's occasionally mouthwatering 1897 tome A History of Fowling.
Surveying the results of all those taste tests of all those birds by hornets, cats, and people, Cott saw both rhyme and reason. He concluded that, in most cases, humans and cats 'agreed with the hornets in rating more conspicuous species as relatively distasteful when compared with more cryptic species... Birds which are relatively vulnerable and conspicuous... appear in general to be more or less highly distasteful – to a degree likely to serve as a deterrent to most predators.'
At the other extreme, birds that have especially inconspicuous or camouflaged appearance, Cott almost cackles, 'are also those which are especially prized for the excellence of their flesh'. The list of these includes the Eurasian woodcock, skylark, and the mallard duck.
Among the widely disliked were kingfishers, puffins, and bullfinches. Cott cautioned his readers that 'palatability may change with growth and age of the bird; and it differs markedly in different parts of the same individual'.
But as with the special case of chickens and eggs, this is neither the beginning of the story nor its end. At roughly the same time, Cott was also running an extensive programme to test the palatability of every kind of bird egg he could find. The titles of his studies are pretty self-explanatory:
> The Palatability of the Eggs of Birds – Illustrated by Experiments on the Food Preferences of the Hedgehog (Erinaceus europaeus)
>
> The Palatability of the Eggs of Birds: Illustrated by Three Seasons' Experiments (1947, 1948 and 1950) on the Food Preferences of the Rat (Rattus norvegicus)
>
> The Palatability of the Eggs of Birds – Illustrated by Experiments on the Food Preferences of the Ferret (Putorius furo) and Cat (Felis catus) – with Notes on Other Egg-Eating Carnivora' (Those other carnivora are numerous, and include civets, mongooses and meerkats, hyenas, dogs and dingoes, otters, aardwolves, and foxes.)
Cott's research programme could (although was not, so far as I know) be summarized as 'Go suck eggs!'
Egg palatability experiments are potentially of great practical value. Island nations, Britain pre-eminently, were and are vulnerable to enemies who would block food shipments from overseas. One could counter the danger by discovering unknown or unappreciated edible native foodstuffs. A simple way to begin: collect bird eggs and test their palatability.
Egg collecting, like other research activities, is not without hazards. Cott relates an incident that's documented in an 1882 monograph: 'The victim, having collected a basket-full of the first eggs of the season, and wishing to procure more, had sent his wife to empty the basket in the village. In her absence, he fixed his rope to the cliff-top and made a second descent. Meanwhile a fox ran up, and gnawed the rope till it severed, at the place where the man had previously rubbed his yolk-smeared hands.'
Cott's experiments mainly addressed a scientific question – demonstrating that, usually, the most conspicuous eggs taste terrible to whatever might want to eat them.
Cott also used human egg taste-testers. In 1946, he entered a six-year collaboration with
|
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Hyperloop" transport system Reuters LA to San Francisco in 30 minutes: Paypal founder Elon Musk unveils 800mph Hyperloop 'trains' hyperloop-3.jpg A sketch of billionaire U.S. entrepreneur Elon Musk's proposed "Hyperloop" transport system Reuters LA to San Francisco in 30 minutes: Paypal founder Elon Musk unveils 800mph Hyperloop 'trains' hyperloop-4.jpg Streamlines for capsule traveling at high subsonic velocities inside Hyperloop spacex.com LA to San Francisco in 30 minutes: Paypal founder Elon Musk unveils 800mph Hyperloop 'trains' hyperloop-5.jpg An image of the Hyperloop passenger capsule with doors open at the station spacex.com LA to San Francisco in 30 minutes: Paypal founder Elon Musk unveils 800mph Hyperloop 'trains' hyperloop-6.jpg Hyperloop capsule in tube cutaway with attached solar arrays spacex.com
An initial A$32m (£18m) will be provided from government grants and a renewable technology fund to get the project off the ground. The total A$800m (£450m) cost is expected to be funded by private investors.
The move comes just two months after Tesla switched on the world’s biggest lithium ion battery to help stabilise Australia’s shaky power infrastructure.
Tesla won a bid in July to build the 129-megawatt hour battery for South Australia, which expanded in wind power far quicker than the rest of the country, but has suffered a string of blackouts over the past 18 months.
Critics of South Australia’s renewable energy push have argued Tesla’s battery is a “Hollywood solution” in a country that still relies on fossil fuels – mainly coal – for two-thirds of its energy.Video footage of students sight-reading a musical score, or reciting a speech from Shakespeare’s “Julius Caesar.” Digital photos of students’ self-portraits. Samples of student-penned research papers and other assignments. Those are the types of documentation hundreds of arts educators in Tennessee recently assembled as evidence of their impact on student learning.
The state this year is ramping up an alternative component to its teacher-evaluation system for the arts that tackles a thorny question many states are grappling with: how to evaluate teachers on student growth when standardized-test scores are not available.
The answer in this Tennessee enterprise is portfolios of classroom work. And not just the final, polished products, but the before and after, showing student improvement over time. Teachers submit their portfolios electronically to the state, and they are scored by trained peer reviewers, who are fellow arts educators.
Three districts participated this past school year in the new system. At least 11 will do so this academic year, including some of the state’s largest districts, according to state officials.
The state this year is also rolling out a similar initiative for world-language teachers. And work is underway on one for those teaching physical education.
The effort comes as many states require that evaluation systems weigh as one component teachers’ contributions to student gains in learning. The issue gets complicated in subjects beyond reading and math for which standardized testing is less frequent or not administered at all. Tennessee has no statewide arts assessments.
Students point to the beginning of a musical measure during Atticus Hensley's band class at East Middle School in Tullahoma Tenn. on Sept. 12.
—Josh Anderson for Education Week
“Teachers want to demonstrate their effectiveness, they really do,” said Dru Davison, the fine arts adviser for the 150,000-student Shelby County district, which includes Memphis. “But they want it to be based on what they actually do in the classroom and the value they bring to their kids. They want to feel empowered and to be honored for the professionals that they are.”
Mr. Davison, who played a lead role in developing the system, added, “If we have accountability systems that go against those principles, then we’re shooting ourselves in the foot.”
'Model' Approach
Laura D. Goe, a research scientist at the Educational Testing Service who is part of its Understanding Teaching Quality Research Group, said she sees real promise in the initiative.
“Tennessee has the right idea in promoting this effort to achieve some rigor and comparability in a set of content that is difficult to measure,” she said. “To me, it is a model for where we want to ultimately go [with teacher evaluation], and where I think we will go in most subjects.”
Indeed, North Carolina is using the Tennessee approach as a model for its own pilot program to evaluate teachers in the arts, world languages, health, and physical education, as well as for those who teach Advanced Placement and International Baccalaureate courses.
Representative of All
The Tennessee initiative began two years ago with a pilot in the Memphis school system (recently merged into a larger district for Shelby County). This past year, 435 educators took part across three districts, state officials said.
Atticus S. Hensley, the band director for two middle schools in Tullahoma, Tenn., who participated this past year and was involved in its design, said many arts educators have welcomed it.
“Half of our evaluation was coming from some source we had no control over,” he said. “For arts teachers, that was really frustrating.”
Sara Heyburn, an assistant commissioner at the Tennessee department of education, said the new measure was developed with a clear eye on that problem.
“We knew there were many subjects and grades for which we didn’t have individual growth measures,” she said. “Ultimately, what we wanted was that the measure first and foremost would be helpful in informing student growth and lead to increased learning for students, but also reflect a spectrum of performance for teachers.”
She also said a priority was to set up a process that educators find beneficial to their practice.
The portfolio evaluation is focused on four domains: perform, create, respond, and connect.
Teachers must submit five batches of student work samples, called “evidence collections,” with a self-rating for each. They also must explain their work and the context for those submissions. At least two of the five collections must show differentiated instruction for students at varying levels of skill and ability and represent growth of students at those levels.
The portfolio generally accounts for 35 percent of a teacher’s score on their evaluation. Fifty percent is based on classroom observations from the school principal. The other 15 percent is based on a different student-achievement component, including data from state tests or other assessments. However, if the portfolio score is stronger than this last measure, it may be used to count for half the teacher’s evaluation.
Mr. Davison from Shelby County said the portfolio is all about evidence of growth.
“You can’t just put in the beautiful, polished performance or painting,” he said. “Also, we’ve got to see how that teacher is impacting kids of different groupings. How are you growing your special-needs kids? If you have [Advanced Placement] kids playing concertos, how are you growing those kids?”
Jeffrey A. Chipman, who teaches vocal music at Bellevue Middle School in Memphis, said the portfolio evaluation is improving his practice.
“To be able to say, ‘This is where they were and this is how I helped them get here’ is powerful,” he said.
Jackie Norman, a visual-arts teacher at Tullahoma High School, was leery when she first heard about the new system, lamenting the “constant evaluation of teachers” in Tennessee. “So our initial reaction was: Another one?”
But she’s now a fan. “It is a true measurement of a teachers’ teaching ability,” she said.
The evidence teachers submit must be pegged to the Tennessee arts standards, be representative of their courseload, and contain evidence of varying time spans (from at least two points in time), a state overview says. Each portfolio is assessed by one peer reviewer, but it’s subject to one or more additional reviews if the score varies significantly from the teacher’s self-assessment.
'Respecting' Teachers
Steven Seidel, the director of the Arts in Education program at the Harvard Graduate School of Education, said that while he’s not examined the Tennessee approach closely, he likes the sound of it, including the level of control handed to teachers—from playing a key role in its development to assembling the portfolios to having other educators conduct the reviews.
“This feels like a really significant... step in the right direction of respecting teachers’ priorities, knowledge, and capacity to make serious evaluative judgments about their own work,” he said. Having other arts educators conduct the reviews “opens up the possibility... of the whole system becoming a really powerful dimension of professional development,” he said.
But Mr. Seidel cautioned that it’s critical to stay the course.
“It’s very important that the state or district stays with the game and doesn’t change the game too often or too fast,” he said. “And there has to be enough support and training” early on for participating teachers.
Marcy Singer-Gabella, an education professor at Vanderbilt University’s Peabody College in Nashville, Tenn., and its associate chairwoman for teacher education, said she appreciates the focus on measures valued by arts educators.
“A real challenge with test-based accountability is the tasks are not recognized as representative of the learning teachers care about,” she said. Here, the idea is for teachers to “select work that represents
|
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] |
ksen.
David Martin
kirjallinen. - (EN) Äänestin Tunisiaa koskevan päätöslauselman puolesta. Mielestäni on ensisijaisen tärkeää, että parlamentti osoittaa kannattavansa varauksetta demokratiaa, oikeusvaltioperiaatetta ja ihmisoikeuksien kunnioittamista Tunisiassa ja muualla Lähi-idässä.
Nuno Melo
Olen tyytyväinen Tunisian mielenosoituksiin, joiden ansiosta Tunisian kansa on saanut jälleen vapauden ja päättänyt nyt asemansa menettäneen presidentti Zine al-Abidine Ben Alin vuodesta 1987 harjoittaman hallinnon. On tärkeää, että Tunisian kaikki poliittiset, yhteiskunnalliset ja demokraattiset voimat saavat nyt asianmukaisen edustuksen, sillä vain näin väliaikaiselle hallitukselle voidaan antaa vaalien valmistelun ja demokratiaan siirtymisen kannalta välttämätön legimiteetti ja kansan luottamus. Katson myös, että meidän on tarkasteltava keinoja Tunisian auttamiseksi, myös rahallisesti, sekä sitä, miten eurooppalainen kansalaisyhteiskunta voi tukea ja auttaa Tunisian kansalaisyhteiskuntaa ja etenkin ihmisoikeusjärjestöjä ja työmarkkinaosapuolia.
Louis Michel
Kannatan Tunisiaa koskevassa päätöslauselmaesityksessä hyväksyttyä kantaa. Tunisia on historiallisessa käännekohdassa: velvollisuutemme on tukea Tunisian kansaa auttamalla sitä vakaan demokratian luomisessa ja tukemalla ja lujittamalla kansalaisyhteiskuntaa, joka neuvotteluvaltansa avulla edistää merkittävästi demokratian lujittamista. Kannatan kaikilta osin Tunisian demokraattista muutos- ja kehitysprosessia. Kannustan näin ollen väliaikaista hallitusta jatkamaan toimiaan sellaisten demokraattisten vaalien järjestämiseksi, joissa kaikki poliittiset tahot ovat edustettuina.
Willy Meyer
Äänestin Tunisian tilannetta koskevan päätöslauselmaesityksen puolesta, sillä olen yhtä mieltä siitä, että meidän on ilmaistava solidaarisuutemme ja tukemme Tunisian kansaa kohtaan, joka on vaatinut demokratiaa ja yhteiskunnallisia parannuksia. Mielestäni on äärettömän tärkeää, että parlamentti asettuu vankasti tukemaan sorrettuja kansoja ja antaa tunnustusta niiden rohkeudelle ja päättäväisyydelle, eli tässä tapauksessa Tunisian kansalle, joka on järjestänyt joukkomielenosoituksia tehdäkseen lopun nyt asemansa menettäneen presidentin Ben Alin tyranniasta. Mielestäni on erityisen tärkeää, että päätöslauselmassa todetaan, että naapuruuspolitiikkaa on tarkistettava, koska - ja olen tuominnut tämän lukuisia kertoja - sillä pyritään pikemminkin tekemään epäoikeudenmukaisia vapaakauppasopimuksia kuin kehittämään ihmisten hyvinvointia ja ihmisoikeuksia tai tekemään loppu autokratioista ja yhteiskunnallisista vääryyksistä. Äänestin tämän päätöslauselman puolesta myös siksi, että minäkin tuomitsen Tunisian hallituksen harjoittaman painostuksen kansalaisten mielenosoitusten aikana, ja koska yhdyn vaatimukseen panna vireille riippumaton tutkimus harjoitetusta painostuksesta ja Ben Alin hallituksen laajasta korruptiosta.
Alexander Mirsky
kirjallinen. - (EN) Sääntönä on, että kun perustuslakia on muutettu ja uusi hallitusmuoto on luotu, maassa on järjestettävä demokraattiset ja oikeudenmukaiset vaalit. Voimme aloittaa keskustelut rahallisesta tai muuntyyppisestä tuesta vasta, kun Tunisia on pannut täytäntöön kaikki Etyjin, Euroopan parlamentin, Euroopan unionin ja Eurooppa-neuvoston suositukset. Historia on valitettavasti opettanut meille, että demokratiaan pyrkivistä maista muodostuu korruption ja väärinkäytösten keskuksia. Tämä on yhteydessä korkeaan rikollisuusasteeseen ja oikeuden ja yhteiskunnallisten sääntöjen rikkomiseen. Äänestin päätöslauselmaesityksen puolesta, kun pidetään mielessä, että Tunisialle on annettava rahallista tukea vasta vapaiden vaalien jälkeen ja rahoitustuesta vastaavien laitosten tiukassa valvonnassa.
Andreas Mölzer
kirjallinen. - (DE) Äänestin Tunisian tilannetta koskevan päätöslauselmaesityksen puolesta, sillä siinä ilmaistaan selkeästi ja tasapainoisesti Euroopan parlamentin kanta Tunisian tapahtumiin. On ensisijaisen tärkeää, että väliaikainen hallitus järjestää vaalit mahdollisimman pian, jotta maa voi siirtyä autoritaarisesta hallinnosta vakaaseen demokraattiseen hallintoon. Päätöslauselmaesityksessä pyydetään myös Catherine Ashtonia ryhtymään pikaisesti toimiin, jotta Tunisialle voidaan antaa sen tarvitsema EU:n tuki.
Franz Obermayr
kirjallinen. - (DE) Euroopan parlamentin Tunisian tilannetta koskevassa päätöslauselmaesityksessä annetaan tunnustus Tunisian kansan pyrkimyksille siirtyä demokratiaan. Siinä korostetaan myös sitä, että on luotava tarvittavat olosuhteet parlamentaarisen yleiskokouksen vaalien pitämiseksi. Tällaisen yleiskokouksen tehtävänä olisi laatia demokraattinen perustuslaki, jolla varmistetaan vallanjako. Turvallisuusjoukkojen harjoittama painostus ja kohtuuton voimankäyttö on tuomittava. Näistä syistä kannatan Tunisian tilannetta koskevaa päätöslauselmaesitystä.
Wojciech Michał Olejniczak
Tunisian viimeaikaisten tapahtumien takia haluan ilmaista solidaarisuuteni maan kansaa kohtaan. Euroopan unionina meidän on tuettava Tunisian kansaa, joka on protesteillaan ja mielenosoituksillaan saanut jälleen vapautensa ja vapauttanut itsensä monia vuosia kestäneestä sortohallinnosta. Haluaisin myös tuomita turvallisuusjoukkojen harjoittaman painostuksen ja väkivallan, joka kohdistui mielenosoittajiin. Yhdyn täysin Euroopan unionin esittämään vetoomukseen. Tunisian tapahtumat ovat valitettavasti paljastaneet jälleen unionin ulkopolitiikan heikkouden. Euroopan ulkosuhdehallintoa ja Euroopan komissiota olisi vaadittava ryhtymään entistä konkreettisimpiin toimiin. Unionin on vaadittava, että yhteisissä ulkotoimissa kiinnitetään su
|
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Pay several times now on my Apple Watch, and not only does that astound the sales clerk, but sends me into paroxysms of giddiness. But there are more sober issues here.
Some merchants, regrettably, remain in denial.
Are you in denial? No I'm not!
Not only do some merchants believe that they have overriding interests that trump customer needs, but their denial extends to skimping on funds for POS equipment replacements and even ignorance. I found this part of a VentureBeat article "The ‘year of Apple Pay’? Fewer than a quarter of top retailers support it" particularly interesting (and alarming).
One recent survey found that a quarter of all retailers don’t understand that come October 1, retailers who have not adopted the EMV technology standard for “chip and pin” payments will assume legal responsibility for credit card fraud. The survey found that 45 percent of those surveyed will very likely miss the October 1 deadline for having EMV points of sale equipment in place.
For some background on the October 1 EMV Liability Shift, see this article I wrote in 2014. To quote:
This liability shift means that those issuers and merchants using non-EMV compliant devices that choose to accept transactions made with EMV-compliant cards assume liability for any and all transactions that are found to be fraudulent.
It defies credulity that many merchants, on notice since mid-2014, are going to miss the deadline. (The VentureBeat article I cited above is sourced from this excellent Reuters report.) Of course, plastic credit cards with chips are EMV compliant, but I don't believe that's the end point, just an intermediate step for many. It's a whole different discussion.
If there's one thing that's becoming clear, it's that corporations (who like to roll money up in the management chain) and governments (who are short of money) who are not accustomed to spending big bucks on first-class security are going to continue to be harmed by their practices. And their customers will suffer along with them.
In fact, this could be a turning point in the future of U.S. business. Corporations that have been notably hacked like Target, Home Depot and Neiman Marcus may be, thankfully, suitable sobered. For example, Target recently did an about face and embraced Apple Pay. Those corporations that don't have technically savvy executive management and don't appreciate what it takes to mitigate the risks may soon be out of business.
More than ever, it's important to decide which companies you can trust, and those executives who think that they can skate on security and skimp on people, resources and equipment may be no longer be with us in a few years.
Next page: the tech news debris for the week of June 1.
Page 2 - The Tech News Debris for the Week of June 1
One of the best articles I've read recently is not from this week specifically, but I found it this week. It's from an excellent technical writer, Andrew Cunningham at ars technica called "Yes, the 2015 MacBook Air supports 4K displays at 60Hz." The thing is, it's been quite an art lately to determine which Macs support 4K displays, and whether the support is a 30 Hz or 60 Hz.
Also, the combination of OS X version and the hardware determines whether you can use single stream mode with DisplayPort 1.2 or whether you may need to use two cables. It's all quite a mess in my mind. While Mr. Cunningham's article doesn't try to span the extent of all the 4K issues and all Macs, his explanation focused on the 2015 MacBook Air brings a whole lot of knowledge and testing to the table. If you're interested in a 4K monitor for any recent Mac of yours, this article is 4K video 101 and must reading.
The next article starts off coyly with...
Ask the average Apple fan to make a list of the important moves the company has made in the past year or so, and the list will probably start with the Apple Watch before ticking off the huge sales of bigger iPhones and the $3 billion deal for Beats Electronics.
But the real breakthrough according to this excellent article is Apple's programming language Swift. "Apple's Biggest Breakthrough That Almost No One Knows About." Swift has some of its roots in the programming language called Haskell, a language known for, amongst other things, not allowing ambiguity to to introduce bugs in the code. (I'll have more to say on this next week.) Meanwhile, if you're curious about Swift and how it's affecting the lives of programmers, this is a good article.
On to the amazing Apple TV, a three year old technology. One of the trends I've noticed in tech reporting is that writers—and I am no exception—try to gather insights from disparate sources and put a picture together about some part of our technology lives. The results are often wrong or mired in opinion. And then, some entity does some bang-up research, and we find out the real details. This next article is one of those. "Apple TV leaps into first place as iOS dominates online video market, Adobe reports." The article is especially notable because it's written by Daniel Eran Dilger—someone who is deep when it comes to all things Apple.
Finally, and it may be just me, but I make a distinction between well-known technical writers who are deep on Apple and writers who publish at popular sites and whose name I never heard of. Often those latter articles look at the surface effects with respect to Apple to paint a broad picture for the mass market. However, in this case, I must say that the author generally gets Apple security situation right while necessarily ignoring the deeper issues.
So take a look, with your critical hat on, at "Apple is having its Microsoft moment." If anything stands out, it's that Apple has been too slow and not rigorous enough in its security fixes to software. Perhaps it's because running scared is unseemly for Apple product managers. Meanwhile, Microsoft, which has been burned badly in the past, seems no longer complacent. And in the software security business, complacency kills. Happily, the article ends on a hopeful note. Which is a good place to end this week's P.D.
________________________
Particle Debris is a generally a mix of John Martellaro's observations and opinions about a standout event or article of the week (preamble on page one) followed by a discussion of articles that didn't make the TMO headlines, the technical news debris. The column is published most every Friday except for holidays.In recent years, an auto-darkening welding helmet has been widely used on welding sites. Such an auto-darkening welding helmet is generally equipped with an auto-darkening filter. The auto-darkening filter can work mainly because it is provided with a liquid crystal panel. The liquid crystal panel is transparent before welding-arc ignition. The liquid crystal panel becomes opaque at the moment of the welding-arc ignition starting, so as to protect an operator's eyes. The auto-darkening welding helmet is usually provided with an adjustment knob or button. Therefore, before wearing the welding helmet, the operator has to hold it in hand to set operating parameters, such as SENSITIVITY, delay time, shade, and weld mode or the like, of the auto-darkening filter. After the setting, the operator can wear the welding helmet to carry out a welding operation.
In case that the operating parameters must be adjusted repeatedly on welding sites (for example to alter the weld mode, SENSITIVITY or the like), repeatedly taking off/wearing the helmet will extremely consume the operator's energy, which may negatively affect the quality of welding. Further, during taking off the helmet, setting the parameters and wearing the helmet again, the operator's eyes have to be continuously self-adjustable to adapt to bright or dark ambient environmental change. Individual operators may even feel discomfort such that their welding work may be affected. In more serious cases their eyes may be permanently damaged.
Take an argon arc welding machine for example. A modern welding apparatus generally comprises an electric welding machine, a gas cylinder, a welding torch and a welding helmet. Before the welding operation is carried out, it is required to correspondingly set parameters of the electric welding machine, such as its electric current, voltage, welding duration time, wire feed speed or the like. The electric welding machine is provided with a display screen on its operating panel to show the parameters and their setting. A cable is connected between the electric welding machine and the welding helmet such that after the relevant operating parameters of the electric welding and the welding helmet have been properly set, the operator can wear the helmet to begin to work.
There is a possibility that the operator is stumbled by the connecting cable between the electric welding machine and the welding helmet. Further, due to its length limitation, the cable may constrain the operator's welding work in a specific circumstance. Furthermore, since the welding environment is usually severe, the connecting cable may become aged after it is used for a long period or may be broken off due to snarling, which may lead to signal connection interruption such that the welding helmet cannot be used normally.Ongoing
Burning Man is coming to D.C.! From March 30, 2018 - January 21, 2019 at The Renwick Gallery (part of the Smithsonian American Art Museum) you can find this amazing exhibition on display. Find out more about this awesome event happening in our nation's capitol here: https://americanart.si.edu/exhibitions/burning-man
6:00 pm
Start the New Year off right
|
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] |
Periodicals, Inc.Billy Goffin
William Charles Goffin (12 December 1920 – 15 September 1987) was an English professional footballer who played in the Football League for Aston Villa and Walsall. He was often referred to by his nickname "Cowboy".
Having previously played locally for Amington Village, Goffin played briefly for Tamworth before moving to Aston Villa as an amateur in August 1937. He signed professional forms with the club in December 1937. During World War II, Goffin made 82 appearances for Villa, scoring 47 goals, and also guested for Tamworth, Birmingham, Leicester City, Nottingham Forest and Swansea Town. In 1952, he scored four goals in a 19–2 win against RAF Lichfield in the Birmingham & District League. He remained at Villa until his transfer to Walsall in August 1954. In all, he made 255 first team appearances for Villa, scoring 89 goals. Of these, 156 appearances and 39 goals came in the Football League. He played for Walsall for one season, making eight League appearances.
In 1955, Goffin became the first manager of Tamworth – the club had previously been run by committee – when he rejoined the club as player-manager. While at the club, he combined his role with a job as a collector for the East Midlands Electricity Board. In February 1958, Goffin resigned as manager and was replaced by Vernon Chapman. He continued playing until the end of the 1960–61 season. He was awarded a testimonial in May 1961.
Managerial statistics
References
Bibliography
Category:1920 births
Category:1987 deaths
Category:Sportspeople from Tamworth, Staffordshire
Category:Association football forwards
Category:English footballers
Category:Tamworth F.C. players
Category:Aston Villa F.C. players
Category:Birmingham City F.C. wartime guest players
Category:Leicester City F.C. wartime guest players
Category:Nottingham Forest F.C. wartime guest players
Category:Swansea Town A.F.C. wartime guest players
Category:Walsall F.C. players
Category:Tamworth F.C. managers
Category:Association football players who received a testimonial
Category:English football managersThe Curiosity rover, is, by general consensus, pretty cool. The peripatetic planetary explorer, aka the Mars Science Laboratory, not only experienced one of the most dramatic and famous landings of all time when it arrived on the Red Planet last summer, it also showed the world was probably habitable in its past. It’s only natural, then, that while Curiosity giveth, sometimes it can also taketh away — in this case, interesting amounts of methane serving as possible evidence of sub-surface bacteria.
Mars Meth(ane) Heads
Perhaps most familiar as a source of energy and heat, methane (CH4) is also common throughout the solar system. Some planets have naturally occurring methane, but most of Earth’s supply of the gas is a result of biological processes. No wonder it’s interesting to Mars researchers: a high amount of the gas could indicate life on the Red Planet to produce it, in the form of underground microbial activity.
Scientists’ extensive observations of Mars, both from Earth and from instruments in Mars orbit, had shown methane to exist there in varying amounts. But not varying over time — varying from observation to observation. From highs of 45 parts per billion by volume (ppbv) ten years ago to more recent observations (over the past two years) of just 7-8 ppbv, there was no clear consensus on methane concentrations in Mars’ atmosphere. In fact, at Gale Crater, Curiosity’s landing site, one set of instruments recorded approximate methane amounts of 15 ppbv in fall to 30 ppbv in winter, while another found 30 ppbv in fall and 5 ppbv in winter.
Enter Sand-Robot
It’s a lucky thing, then, that Curiosity has an instrument that can specifically measure methane amounts (the Tunable Laser Spectrometer, part of the Sample Analysis at Mars suite). Surely, with its history of providing tantalizing information revealing the Red Planet’s life-harboring abilities, the roving robot’s methane analysis would be similarly upbeat, right?
Nope. “To date we have no detection of methane,” write the authors of a study in today’s Science, announcing Curiosity’s disappointing findings. Their figures indicate a maximum amount of just 1.3 ppbv for methane in Mars’ atmosphere. It’s surprising but not shocking, since there was already so much confusion about the methane levels. (Plus a fair amount of controversy, since anything that has to do with extraterrestrial life often leads to emotional rather than rational discussion.) It’s possible the previous findings were accurate, and that some unknown process has destroyed or removed the methane (such as a dust devil creating an electric field that zaps away the gas), but there’s no evidence to support this.
So it looks like reports of underground life on Mars have been greatly exaggerated. To be sure, the odds of Mars currently hosting life were never enormous, but now they’re that much lower. (But still not zero!)
Curiosity’s findings don’t always prove breathtaking, but this one at least is still scientifically interesting. Why did all those previous observations measure so much methane? And now that methane isn’t likely a factor, what else can the rover look for that might suggest biological activity? Just because the answer’s “no” doesn’t mean the question wasn’t worth asking.Shelby County Commissioner Justin Ford pleaded to one count of misdemeanor domestic assault Tuesday and was sentenced to a year of probation.
After entering an Alford plea to the charge, Ford issued an apology outside the courtroom.
"I truly am sorry for anything or any negative light that I brought to the constituency," he said.
An Alford plea allows a defendant to state that he is not guilty, while pleading to an agreed settlement in his best interest.
Special Judge Terry Lafferty sentenced Ford to 11 months 29 days probation. Ford will receive a day credit for jail time after he was arrested. He will also be required to go to anger management courses.
The case stems from an April 23 incident in which authorities said Ford was a passenger and his girlfriend of two years was the driver of a Mercedes when Ford "became belligerent" and hit her on the side of her face.
Authorities said she pulled into a parking lot at Church's Chicken, 925 Poplar Avenue, and tried several times to get out of the vehicle. Ford is accused of pulling her back into the car, punching her, pulling her hair and choking her, according to court records.
"Ford continued to assault (her) inside her vehicle until police arrived," according to an affidavit. "She was treated by (Memphis Fire Department) on the scene."
The affidavit says the information is based on a witness statement.
Ford was charged with aggravated assault/domestic violence and false imprisonment. He was released on $15,000 bond and ordered to wear an ankle monitor.
"The woman that I'm accused of assaulting, I love with all my heart," Ford said. "She was a best friend then and still is a best friend now."
Ford had been scheduled for a preliminary hearing Tuesday and the woman in the case was subpoenaed to come to court. Tuesday's court date began with the woman's attorney, Dewun Settle, discussing a motion to quash the subpoena for her to appear.
"We didn't think that she should have to appear pursuant to a subpoena," Settle said.
Regarding Ford's sentence, Settle said she had been consulted and she is "satisfied with the outcome."
Ford's plea could have implications for his seat on the County Commission.
Shelby County Attorney Kathryn Pascover, District Attorney Amy Weirich or the state attorney general can initiate an "ouster" lawsuit to remove Ford from office based on a provision in state law that forbids legal violations involving "moral turpitude." State law is silent about whether domestic violence or simple assault qualify as moral turpitude.
If a judge finds Ford guilty of an act which violates a criminal statute involving moral turpitude, he would be removed from office and the County Commission could appoint someone to serve in his place until the next election.
Pascover wasn't immediately reachable for comment and Weirich said she hasn't given any thought yet to whether she'll pursue an ouster lawsuit.
Shelby County Commission Chairman Melvin Burgess said the commission is aware of Ford's plea agreement.
"Neither state law nor the county's charter provide a means by which the County Commission may unilaterally remove one of its own members from office," Burgess said. "Consequently, any decision re: Commissioner Ford's future must be determined through the legal process, the voters or Commissioner Ford."
Commercial Appeal Reporter Ryan Poe contributed to this story.
/*
* Part of the LLVM Project, under the Apache License v2.0 with LLVM Exceptions.
* See https://llvm.org/LICENSE.txt for license information.
* SPDX-License-Identifier: Apache-2.0 WITH LLVM-exception
*
*/
#ifndef EXPAND_H_
#define EXPAND_H_
/** \file
* \brief various definitions for the expand module
*/
#include "gbldefs
|
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] |
Natural History Museum. A great collection of tarantula moults, birds nests and rocks! I should really have tucked my shirt in.
Some of the questions were quite a challenge. Mainly because although I should have I had not thought about them before. I was almost thrown by questions such as, ‘what is the rarest plant that you have collected?’, ‘what is the oldest plant that you have collected?’ and ‘how many new species have you discovered?’. On the basis of my answers I am not sure how well I would fair in a job interview. I was very pleasantly surprised to meet so many children with a spontaneous enthusiasm and interest in natural history and plants! I was also very impressed with how friendly and polite the children (and staff) were and of how well supported learning seemed to be at St Keyna’s. So all in all a very positive experience that I would gladly repeat.
Motacusal community members finishing the pollarding of their plot. Although ready to pollard since October there have been delays due to El Niño and the Brazil Nut harvest
Two years after planting our first plot at Motacusal, the community has just completed the first pollarding. The dense canopy of Inga trees has been reduced to a green mulch and the main stems taken away to be stored for fuel wood leaving about 1/3 ha of fertile ground for growing annual crops such as maize, rice or beans. The pollarding is the culmination of over two years work and testimony to the skills and hard work of our field team, lead by Forest Engineer, Rolman Velarde. We will leave the mulch to rot down a little and in a month the first crops will be sown.
Once the main stems have been cut, the smaller branches, twigs and leaves are left in the plot as mulch, providing much needed organic matter for the soil. Image: Rolman Velarde (Herencia)
Management of the Motacusal plot is being overseen by the communitie’s children through the ‘Bosque de los Ninos‘ programme which means that they get to choose what will be sown. This is not just important for the engagement of children but also for the community as a whole, linking our demonstration / trial plots with their most valued resource and bringing it to fruition is a powerful symbol. The children have been experimenting with growing various seeds for planting as part of the ‘productive’ part of their school curriculum and I am keen to see what has been planted in a month’s time. There stil remain some challenges though. The anomalous weather associated with El Niño could lead to the crops failing or to the pollarded Inga not recovering as planned.
Rolman Velarde explaining to the other participating communities how to pollard Inga trees for alley cropping. Image: Victor Soruco, Herencia.
We used the opportunity of this being the first plot to be pollarded to invite representatives from the other particpating communities: Palacios, San José, Jerico and Monte Sinai. This enabled us to train them in pollarding but also for them to get an idea as to what their agroforest plots will look like in a year or so.<!doctype html>
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<li data-value="public">Public</li>
<li data-value="protected">Public/Protected</li>
<li data-value="private" class="selected">All</li>
</ul>
</div>
<input type="checkbox" id="tsd-filter-inherited" checked />
<label class="tsd-widget" for="tsd-filter-inherited">Inherited</label>
<input type="checkbox" id="tsd-filter-externals" checked />
<label class="tsd-widget" for="tsd-filter-externals">Externals</label>
<input type="checkbox" id="tsd-filter-only-exported" />
<label class="tsd-widget" for="tsd-filter-only-exported">Only exported</label>
</div>
</div>
<a href="#" class="tsd-widget menu no-caption" data-toggle="menu">Menu</a>
</div>
</div>
</div>
</div>
<div class="tsd-page-title">
<div class="container">
<ul class="tsd-breadcrumb">
<li>
<a href="../globals.html">Globals</a>
</li>
<li>
<a href="../modules/_comps_counterinputcomponent_counterinputcomponent_.html">"comps/counterinputcomponent/CounterInputComponent"</a>
</li>
<li>
<a href="_comps_counterinputcomponent_counterinputcomponent_.counterinputcomponent.html">CounterInputComponent</a>
</li>
</ul>
<h1>Class CounterInputComponent</h1>
</div>
</div>
</header>
<div class="container container-main">
<div class="row">
<div class="col-8 col-content">
<section class="tsd-panel tsd-hierarchy">
<h3>Hierarchy</h3>
<ul class="tsd-hierarchy">
<li>
<span class="target">CounterInputComponent</span>
</li>
</ul>
</section>
<section class="tsd-panel">
<h3>Implements</h3>
<ul class="tsd-hierarchy">
<li><span class="tsd-signature-type">unknown</span></li>
<li><span class="tsd-signature-type">unknown</span></li>
</ul>
</section>
<section class="tsd-panel-group tsd-index-group">
<h2>Index</h2>
<section class="tsd-panel tsd-index-panel">
<div class="tsd-index-content">
<section class="tsd-index-section tsd-is-external">
<h3>Properties</h3>
<ul class="tsd-index-list">
<li class="tsd-kind-property tsd-parent-kind-class tsd-is-external"><a href="_comps_counterinputcomponent_counterinputcomponent_.counterinputcomponent.html#_countervalue" class="tsd-kind-icon">_counter<wbr>Value</a></li>
<li class="tsd-kind-property tsd-parent-kind-class tsd-is-external"><a href="_comps_counterinputcomponent_counterinputcomponent_.counterinputcomponent.html#counterrangemax" class="tsd-kind-icon">counter<wbr>Range<wbr>Max</a></li>
<li class="tsd-kind-property tsd-parent-kind-class tsd-is-external"><a href="_comps_counterinputcomponent_counterinputcomponent_.counterinputcomponent.html#counterrangemin" class="tsd-kind-icon">counter<
|
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] |
- From Final Fantasy VII
Designed by Cid Highwind, and at times stolen by the Shinra Corporation, this is the most famous of all Final Fantasy vehicles! The High Wind measures at over 6 inches longWorld War IVThe Long Struggle against Islamofascism
by Norman Podhoretz
New York: Doubleday, 2007. 230 pp. $24.95.
Reviewed by Michael Rubin
Middle East QuarterlySpring 2008
https://www.meforum.org/1917/world-war-iv
In World War IV, Podhoretz, a doyen of the neoconservative intellectual movement, places the struggle against Islamism in its historical context. He suggests that U.S. inaction in the face of decades of Middle Eastern terrorism served to embolden terrorists and that while 9-11 shocked U.S. policymakers and the public, it was in fact only the most sensational of a string of terrorist attacks that had seldom drawn reprisals.
For George W. Bush, however, 9-11 would instigate a break with past indifference to terrorism. In a September 20, 2001 address before Congress, Bush linked security at home with freedom abroad. As the Bush doctrine expanded beyond Afghanistan to the Middle East, traditional realists called foul. Former national security advisor Brent Scowcroft condemned any action that might destabilize Arab autocracies. Pat Buchanan, Robert Novak, and Juan Cole hinted darkly at a conspiracy among Bush's Jewish advisors and argued that the roots of anti-U.S. terrorism lay in Washington's support for Jerusalem.
Podhoretz is not surprised but disagrees. He notes that foreign policy-related conspiracy theorizing has frequently been a feature of the domestic political debate during world wars. He draws parallels between pro-Nazi isolationists such as Charles Lindbergh with the Buchanans and Noam Chomskys of today. He accuses liberal internationalists of maintaining "a virtually religious commitment to negotiations as the best, or indeed the only, way to resolve conflicts" and says they have "unshakable faith in the U.N. and a corresponding squeamishness about military force." Not only did such a traditional diplomatic approach fail to defend U.S. security in the run-up to 9-11, Podhoretz argues, but perhaps more importantly, these liberal internationalists risked losing their "comfortable lodgings within the old foreign policy establishment" in the post-9-11 era. Such men ended up making common cause with isolationists and realists in order to launch an insurgency against the Bush administration's foreign policy.
World War IV is provocative and not without its flaws. Podhoretz's lecturing tone is distracting, and he leaves many points hanging. The Islamist challenge and the roots of Islamist ideology deserve more attention. Describing the foreign policy establishment's actions as an insurgency is welcome, but how did these forces grow so powerful? Did Bush not control his appointees? Was his management competent? Or perhaps Bush's rhetoric was less than sincere, a cynical ploy to avoid criticism from men like Podhoretz. The omission of leading insurgents, such as Deputy Secretary of State Richard Armitage (cited only in one footnote) and Policy Planning Director Richard Haass, is noteworthy. Still, World War IV is a must-read for any foreign policy scholar or practitioner, all the more so given the entry of Podhoretz's arguments into the 2008 U.S. presidential campaign as the candidates debate what to do about Iran and radical Islam.
Related Topics:Radical Islam, War on terror | Michael Rubin | Spring 2008 MEQreceive the latest by email: subscribe to the free mef mailing listThis text may be reposted or forwarded so long as it is presented as an integral whole with complete and accurate information provided about its author, date, place of publication, and original URL.The New Stuff
The first season of Kick Buttowski: Suburban Daredevil brought the world of animated comedic adventure to all new levels for Disney XD. Now that the second season has launched, hold on to your hats! Er… helmets! In addition to all the regular hijinx, Disney has dozens of special guest stars just lining up to provide their voices for characters. Included on the celebrity dream team are NBA star Dwight Howard, Emmanuelle Chriqui, Tony Hawk, Ed O’Neill, Rico Rodriguez, Debby Reynolds, Will Forte, Jay Harris, and many more. Check out the latest new episode this Sunday, September 11th, at 8:30pm on Disney XD, with a new episode to follow every Sunday in that time slot.
Nintendo Wii U and 3DS Giveaways
ToonBarn
ToonBarn shares the latest animation news on all your favorite cartoons! With several updates every day, and hitting hundreds of thousands of regular visitors every month, ToonBarn.com has your toons covered.How to reduce raw material inventories ThyssenKrupp Aerospace
How to reduce raw material
inventories
ThyssenKrupp Aerospace
The challenge
Alu m in u m
Steel
Titanium
Aluminum-Bronze
Nickel
Copper
optimize material
consumption
As credit has tightened, a company’s need
to generate cash has never been greater.
However, because customers and suppliers
are in the same position, the traditional
approach of ‘pay late and get paid early’
doesn’t work.
Companies have therefore looked at other approaches including
reductions in material inventories.
The problem is how to achieve this without disrupting production.
To meet production needs, a company needs sufficient material to
meet its usage and at the same time to provide a buffer against
variations caused by sudden changes in supply or demand.
In reality, because of poor analysis or a lack of trust in supplier
performance, companies also carry further inventory on a
just-in-case basis.
The process...
By working closely with customers, we have been able to develop some
advanced tools which simplify analysis. We use these to devise novel supply
arrangements, which result in significant inventory reductions combined
with high standards of on-time delivery performance.
... to a customized solution
...to
The manufacturer enters parts requirements
into joint EDI system.
At ThyssenKrupp Aerospace operators prepare
parts in accordance with the agreed service level
agreement.
Material is packaged to protect components.
Material is delivered to the manufacturer’s
point of use.
Full online visibility of parts inventory and
min/max levels.
The case study
This approach was taken with a leading global
aerospace manufacturer:
The ThyssenKrupp Aerospace planning team
reviewed the customer’s demand forecast for
cut to size tube and bar and following an
electronic upload was able to use its planning
software to compare the future with its historical
usage.
This enabled forecast accuracy and other
variables such as mill lead times to be
established and an initial forecast by part
number was produced.
It was agreed that the customer’s inventory
should be reduced to one week. To support the
change, ThyssenKrupp Aerospace agreed to
carry a buffer to instil confidence and bought
back the customer’s excess inventory.
Within 6 months of the change this buffer was
reduced and the increase in confidence
encouraged the customer to outsource the first
stage of processing which resulted in reduced
material use and improved process flows.
The benefits of this
approach were as follows:
Inventory reduced from
6 months usage to
5 days worth €2.1 m
1000 m2 of storage
and processing space
converted to high value
assembly work
Materials costs reduced
by 5%
On-time delivery and
right first time quality
consistently exceeded
99%
UNITED KINGDOM
CANAD A
UNITED STATES
C HINA
FRANCE
T AIWAN
INDIA
GERMANY
MEXICO
N ETHERLANDS
POLAND
BELGIUM
FINLAN D
BRAZIL
TUNISIA
AUSTRALIA
Africa
Tunisia, Tunis
+216 29 432 402
The Americas
Brazil, Taubaté
Canada, Montreal
Mexico, Querétaro
USA, Hutchinson, KS
USA, Indianapolis, IN
USA, Seattle, WA
+55
+1
+52
+1
+1
+1
12 362 72300
514 782 9500
442 192 4089
620 802 0900
317 217 1560
253 239 5700
Asia Pacific
Australia, Sydney
China, Shanghai
China, Xi’an
India, Bangalore
Taiwan, Taipei
+61
+86
+86
+91
+886
297 577 777
21 5665 5959
29 8665 8857
80 4040 7529
87 8076 69
Europe
Belgium, Lokeren
Finland, Jämsänkoski
France, Paris
Germany, Frankfurt
Netherlands, Venlo
Poland, Warsaw
UK, Birmingham
+32
+358
+33
+49
+31
+48
+44
9 348 49 21
20 127 4400
1 30 69 67 00
6104 648750
77 324 9999
22 594 08 20
121 335 5100
|
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] |
Aging, have
been established. In 20 s t a t e s, including Arizona, the Advisory Council is
associated with an umbrella agency, such as the Department of Economic
Security.
Appendix I V contains a f u l l text of the recommendations of the Section on
Government and NonGovernment Organizations. ** Appendix V contains the r e s u l t s of the s t a t e survey by the Office of the
Auditor General on Advisory Councils on Aging.
CONCLUSION
Since its inception in 1966, the Advisory Council on Aging has been subjected
t o t h e e f f e c t s of three departmental relocations, eleven organizational
relocations and nine changes of leadership for the Older Americans Act program
i n Arizona. In addition, the Council is substandard i n s t a f f i n g and budget for
its operations when compared with two other Governor's Advisory Councils. This
has impaired the Council's effectiveness in providing advice t o the adminis-tering
s t a t e agency on problems and matters related t o the s t a t e plan on aging
and i n its functioning as a Governor's Advisory Council.
RECOMMENDATION
It is recommended that consideration be given t o the following options:
The Governor c l e a r l y e s t a b l i s h t h e purpose and
independence of the Advisory Council on Aging to
insulate it from organizational and leadership
changes in the administering s t a t e agency.
Consideration should also be given t o designating the
Department of Economic Security as only the
administering agency. In addition, the Governor and
Legislature need t o s p e c i f i c a l l y i d e n t i f y resources
and s t a f f t o support the Council.
2. A s recommended i n the 1971 White House Conference on
Aging, the Governor and Legislature should establish
an agency or office on aging reporting d i r e c t l y to
the Governor with an advisory council providing
citizen input.
Legislation must be enacted i n order t o implement e i t h e r of these
recommendations.
FINDING I1
THERE IS A CONFLICT BETWEEN ARIZONA STATE LAW AND FEDERAL REGULATION
REGARDING THE MEMBERSHIP OF THE ARIZONA ADVISORY COUNCIL ON AGING. AS A
RESULT, THE MEMBERSHIP OF THE COUNCIL HAS NOT BEEN I N COMPLIANCE WITH FEDERAL
REQUIREMENTS.
Federal regulations require t h a t a t l e a s t half of the Advisory Council on Aging
members be actual consumers of services provided under the Older Americans Act.
Arizona law, however, only requires that a majority of the council members be
actual or potential consumers of services provided under the Older Americans
Act. This conflict between the Arizona law and federal regulation has, i n the
past, resulted i n a council membership not i n compliance with federal require-ments.
Federal regulation 1321.50 ( c) from the Department of Health, Education and
Welfare, Office of Human Development, Administration on Aging s t a t e s i n part:
"... at l e a s t one- half of the committee ( t o advise the
Governor, s t a t e agency and single organizational unit on
the implementation of the s t a t e plan) s h a l l consist of
actual consumers of services under t h i s program, including
low income and minority older persons, a t l e a s t i n propor-tion
to the number of minority older persons i n the state."
( Emphasis added)*
However, Arizona Revised Statute Section 46- 183- B s t a t e s i n part:*
" the advisory council on aging s h a l l be composed of
f i f t e e n members, appointed by t h e d i r e c t o r, subject t o
approval by the governor. A t l e a s t eight of the members
shall be consumers or potential consumers of services
provided under the Older Americans Act of 1965, as
amended. Members appointed t o the council s h a l l... be
selected with due regard to geographic and other elements
of representation." ( Emphasis added)
A f u l l text of federal regulation 1321.50 ( c) and ARS Section 46- 183- B
is included i n Appendix I.
The use of the word llpotentialn i n ARS Section 46- 183- B has caused the Council
membership t o not be in compliance with federal regulations. This noncom-pliance
issue was pointed out to the Department of Economic Security by federal
evaluators on several occasions. For example:
In a March 23, 1976, federal assessment of the Arizona Advisory Council, it was
noted:
Itthat a t l e a s t one- half of the membership of the committee
( Council ) consists of consumers, including proportional
low- income and minority representation is questionable a t
the present time... Composition of the Advisory Committee
( Council) may not conform t o T i t l e I11 regulations. The
Governor of Arizona w i l l appoint five persons to the
f i f t e e n member advisory body. Hopefully, his appointments
w i l l be made with T i t l e I11 regulations pertaining to t h i s
issue i n mind. The matter should be brought t o his
attention."
In a January 20, 1978, assessment, federal o f f i c i a l s observed:
" The Advisory Committee ( Council) was not i n compliance
with the requirement s t i p u l a t i n g t h a t over 50% of its
membership be older persons who are a c t u a l service
consumers under the State Plan... In order to bring the
Advisory Committee ( Council) into compliance with
regulations guiding its creation and function, steps
should be taken immediately t o reorganize the Committee's
composition so t h a t a t l e a s t a simple majority of its
members be actual service c o n s ~ m e r s. ~
In a March 14, 1978, l e t t e r t o the Health, Education and Welfare ~ e g i o nI X
Director of Administration on Aging, the Acting Director of the Department of
Economic Security conceded t h a t the Council was not i n compliance with federal
requirements. The Acting Director stated:
" We are well versed on Federal Regulation 903.5*, and
share your concern regarding actual consumer
representation on t h i s Council. A s evidenced by Arizona
Revised Statute 46- 183 ( quoted i n your report), there has
been some d i f f i c u l t y in getting t h i s point across i n the
past. The d i f f i c u l t y is compounded by the f a c t that t h i s
is now a dual- purpose Council which also advises the
Governor. Furthermore, it is the Governor who makes the
f i n a l decision regarding membership appointments.
However, we do feel that great progress was made i n the
recent appointments t o the Council. O f the four new
members, three were actual consumers. This raised our
actual consumer representation from approximately 7% t o
27%. It should be noted that, of our current membership,
a l l but one ( the Native American) are 60 years of age or
over.
Although we now have an unexpired term to be f i l l e d on the
Council, due t o the resignation of Monsignor Donohoe, we
cannot assure t h a t the new appointee w i l r be an actual
consumer. Realistically, we w i l l be looking toward
December 31 and the expiration of five more terms before we
can make any further progress i n t h i s area."
The Region I X Director responded to the Acting Director of DES on March 28,
1978, that:
" A s i g n i f i c a n t i s s u e which remains is the consumer of
services issue. The Arizona s t a t u t e allowing potential
consumers of service is contrary t o present Federal
Regulations requiring the majority membership of the
Advisory Council t o be actual consumers of services. This
is defined as habitual recipients of services funded under
T i t l e I11 and VII of the Older Americans Act.
Presently, the Advisory Council is out of compliance with
the Federal Rules and Regulations. Please advise me of the
action which you intend t o take t o correct the situation."
On May 5, 1978, the Acting Director of DES advised the Region I X Director that:
" As indicated i n our previous l e t t e r, we have taken steps
to increase the number of consumer members on the Advisory
Council. We w i l l take the appropriate steps to remove from
the s t a t e s t a t u t e s the word potential regarding consumers,
and thereby bring the s t a t u t e s into conformity with the
federal regulations."
Federal regulation was renumbered t
|
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823,
295,
2140,
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337,
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50276,
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269,
10422,
1963,
310,
1160,
432,
247,
2590,
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310,
670,
253,
1979,
273,
271,
3388,
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3541,
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18421,
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19781,
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25397,
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342,
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597,
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42626,
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1980,
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247,
4942,
1846,
8984,
15,
29621,
15979,
281,
697,
12340,
275,
20292,
285,
1971,
33433,
403,
16318,
15,
329,
1029,
4248,
273,
18910,
310,
3058,
281,
1056,
253,
6120,
285,
2007,
789,
310,
2424,
281,
19148,
253,
4451,
7794,
273,
436,
8984,
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20292,
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%subscript0
%subscript2 = mul i64 %subscript1, %o
%subscript = add i64 %subscript2, %k
%idx = getelementptr inbounds double, double* %A, i64 %subscript
store double 1.0, double* %idx
br label %for.k.inc
for.k.inc:
%k.inc = add nsw i64 %k, 1
%k.exitcond = icmp eq i64 %k.inc, %o
br i1 %k.exitcond, label %for.j.inc, label %for.k
for.j.inc:
%j.inc = add nsw i64 %j, 1
%j.exitcond = icmp eq i64 %j.inc, %m
br i1 %j.exitcond, label %for.i.inc, label %for.j
for.i.inc:
%i.inc = add nsw i64 %i, 1
%i.exitcond = icmp eq i64 %i.inc, %n
br i1 %i.exitcond, label %end, label %for.i
end:
ret void
}
See-Through Microchip Organs Help Scientists Test New Drugs
To perfect new medicines and surgical techniques, scientists need to conduct experiments on real humans. The only problem is, there aren’t too many living people who want to be guinea pigs for untested drugs or procedures. Human cadavers will work, but it’s not the same as a living, breathing person. Now, scientists from Harvard University have partnered with the Defense Advanced Research Projects Agency (DARPA) to create a series of see-through computer chips that imitate the function of real human organs. The organs-on-chips will allow researchers to study complex human physiology safely without a human subject.
So far, experts at Harvard’s Wyss Institute for Biologically Inspired Engineering have designed small variety different microchip versions of human organs, including the lungs, heart, and intestine. Each faux organ is made from a clear flexible polymer and is about the size of an average computer memory stick. The microchip organs feature hollow microfluidic channels that are lined with living human cells. Although they don’t resemble the real shape of these organs inside the body, the cells allow scientists to observe how these organs might react to new drugs. This process could greatly reduce the number of unsafe drugs that make it to the market, since early stages of “human” testing could be accomplished without having to gather and monitor real study participants. Being able to test drugs directly on a fake human body could eliminate the need for animal testing as well.
The collaborative team hopes to recreate at least 10 of the body’s most essential organs, eventually connecting them together to more closely mimic whole body physiology. According to Jesse Goodman, FDA Chief Scientist and Deputy Commissioner for Science and Public Health, the automated human-on-chip instrument being developed “has the potential to be a better model for determining human adverse responses. FDA looks forward to working with the Wyss Institute in its development of this model that may ultimately be used in therapeutic development.”A young mother was fatally shot Tuesday and her body was burned in the woods behind her house. Her five-year-old son was shot multiple times. Despite being left to die, the child is recovering in a Jackson hospital.
The woman's boyfriend has been charged in the shootings.
Marcus Gardner, 22, has been charged with murder in the fatal shooting of his girlfriend, 21-year-old Chelsea Pace of Starkville, and aggravated assault in the shooting of her son.
An autopsy will be conducted tomorrow but Pace appears to have died from a single gunshot wound to the face, according to Noxubee County Coroner R.L. Calhoun.
Initial evidence from the crime scene suggests she died inside her home off of Highway 388 and was dragged out of the back door into the woods, 10 to 20 feet behind the house, Calhoun said.
Pace's body was recovered Tuesday morning, "badly burned." The accelerant is unknown but Calhoun said the scene smelled of gasoline. A gasoline container has not yet been found, he said. Calhoun could not comment on the murder weapon.
The child was shot "multiple times," and is listed in stable condition at University of Mississippi Medical Center in Jackson.
The couple "hadn't been together that long," Calhoun said.
According to Calhoun, the couple recently moved to Noxubee from Starkville. Gardner is not the child's father, Calhoun said. He added that the boy's father is currently deployed.
When asked if the couple had prior domestic violence calls, Calhoun said, "Not here but we're looking in Starkville."
According to the Oktibbeha County Sheriff's Department, there were no domestic violence calls regarding the couple. Neither Gardner's name or Pace's name was in the system at the Starkville Police Department, according to public information officer Corporal Brandon Lovelady.
Officials with the Noxubee County Sheriff's Department were not available for comment. Further details were not immediately available.
ContactSarah Fowler at 601-961-7303 orsfowler@gannett.com. Follow her onFacebook andTwitter.Selenium and human health implications in California's San Joaquin Valley.
An evaluation was conducted on the human health impacts of elevated levels of selenium in the Kesterson National Wildlife Refuge and its surroundings in Merced County, California. Investigative activities of various agencies were summarized and assessed. Agricultural waste water not intended for human use showed elevated selenium concentrations of up to 1400 ppb. Levels of selenium in fish (up to 96 ppm, wet weight), aquatic birds (up to 130 ppm in liver, dry weight), and waterfowl (up to 5.3 ppm flesh, wet weight) were unsafe for unrestricted human consumption. Data on selenium in drinking water (less than 10 ppb), animals (mean values: beef liver 0.3-0.35 ppm, wet weight; milk, 0.01-0.02 ppm), and air (particulate, 14.8 ng/m3; gaseous, less than 1080 ng/m3) did not suggest a high level of exposure. Selenium concentrations in soil were highly variable and suggested a potential source of high exposure. Selenium values in blood and urine of workers were within normal range. A community health survey did not show any trend of adverse health effects in the local population.We often have quite a lot of used parts for sale from winches that we have re-engineered. Many of these used parts are still fully serviceable such as the Tost drums and brake parts shown below. These could save your club a lot of money if you can't afford to upgrade your winch. You may also find that some of these parts are no longer available from their original suppliers.
We also re-condition some components such as the Tost roller box assemblies shown below. Again, you may find these parts are difficult to obtain. We will also consider part exchanging components if yours are saleable or are still good enough to be re-furbished.
We haven't shown our complete stock of parts below so please do not hesitate to contact us if you are looking for new, used or re-furbished parts for any make of winch - we will more than likely be able to help in some way or other.Bulimia in adolescents: a review.
This report reviews the occurrence of bulimia in female adolescents, a relatively common disorder. Features contributing to its occurrence in adolescents and treatment modalities are highlighted. A high degree of suspicion is needed to make the diagnosis and further work is required to clarify the unique aspects of this disorder in adolescents.The prevalence of human papilloma virus DNA in women with mucopurulent endocervicitis.
The aim of the study was to determine the prevalence of human papillomavirus (HPV) infection in a group of patients with mucopurulent endocervicitis. One hundred and forty-eight patients who came for their routine medical screening and were diagnosed with mucopurulent endocervicitis were enrolled in the study. HPV DNA was sought in cervical swab specimens placed in digene transport medium by use of the Digene Hybrid Capture assay. HPV infection was detected in 5.4% (8/148) of the patients with mucopurulent endocervicitis. The mean age of the patients was 36.4+/-8.2 (18-54) years. Approximately 40% (59/148) of the patients used intrauterine devices currently or in the past, while 16.2% (24/148) used combined oral contraceptives as the contraceptive method. HPV DNA was detected in eight patients: five had infections with low-risk subtypes, one with high/intermediate risk subtypes and one with the combination of high- and low-risk subtypes. The mean age of the HPV infected patients was significantly lower than the HPV negative patients (28.2+/-6.3 versus 36.9+/-8.1 years, p = 0.003). Risk factors for HPV infection did not differ between the infected and uninfected groups. HPV infection should be sought in patients with clinical evidence of mucopurulent endocervicitis even without risk factors for cervical neoplasia.
Getting Users For Your New Startup - pud
http://blog.pud.com
|
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and the Punta di Pesaro. They had appeared first of all in the Milano Marittima, beyond the dockland canal of Cervia, having rented a lovely room in the Hôtel Mare e Pineta. After a week, they had moved to Cesenatico, to the Hôtel Britannia. And then, inspiring fierce indignation and endless rumors everywhere, they gradually progressed to Viserba, Rimini, Riccione itself and Cattolica. They travelled by car: a red two-seater Alfa Romeo 1750 of the Mille Miglia type.
Around the 20th of August, apparently without a care in the world, there they were once more in Riccione, set up in the Grand Hôtel as they had been some ten days earlier.
The Alfa Romeo was brand new. Its engine gave a kind of growl. As well as for traveling, the two friends also employed it for the _passeggiata_ every evening, when, at sunset, the crowd of bathers returned from the strip of sand to saunter along the promenade. Deliliers always drove. Blond, tanned, beautiful in his tight-fitting T-shirts and cream-colored woolen trousers (his hands, negligently draped over the steering wheel, were adorned with fretted, shammy-leather gloves about whose cost no one could harbor any doubts)—clearly it was only to him, to his exclusive whims, that the car responded. The other did nothing.
Wearing passenger goggles (he was never separated from them, not even when the automobile, cutting through the crowd with some difficulty, had to idle along a stretch of the avenue outside Cafe Zanarini at a walking pace), he would let himself be chauffeured up and down, seated complacently next to his companion.
They continued to sleep in the same room, to eat at the same table.
And they sat at the same little table even in the evenings, when the Grand Hôtel's orchestra, having had their instruments transported from the ground-floor dining hall to the terrace exposed to the sea breeze, moved on from strains of light music to modern and jazz numbers. Soon the terrace would fill up—often enough I even went there myself with friends I had met on the beach—and Deliliers would never miss a single tango, waltz, two-step, nor a "slow" dance. Of course, Fadigati never danced. Every now and then taking to his lips the straw tilted above the rim of the glass, with his round eyes he never stopped following the suave moves that his distant friend accomplished, his arms always embracing the most elegant, the most conspicuous girls and women. Returning from their drives, both of them would immediately go up to their room to don their smoking jackets. Sober, heavy black material, Fadigati's; Deliliers's a white jacket, close fitting and cut short at the sides.
Life at the beach they also shared together: except that in the morning it was usually Fadigati who left the hotel first.
He would arrive when there was almost nobody else around, between eight thirty and nine o'clock, respectfully greeted by the bathing attendants, to whom, by their own account, he was always very generous with tips. Dressed from head to toe in normal city clothes (only later, when the heat increased, would he decide to shed his tie and shoes, but never his white panama hat, with its brim lowered over his eyes—that he kept on), he would go to sit under the solitary beach umbrella which he had asked to be planted farther forward than all the rest, just a few yards from the shore. Stretched out on a reclining deckchair, his hands linked behind his neck and a detective story open on his knee, he would remain like that for a good two hours, staring at the sea.
Deliliers never joined him before eleven o'clock. With his svelte stride of a lazy animal, made still more elegant by the slight impediment of clogs, there he would be, crossing without hurry the clearing of burning sand between the beach huts and the bathing tents. He, by contrast, would be almost naked. The white bathing trunks which he was just at that moment finishing lacing up on his left hip and the same gold chain which he always wore round his neck, and from which dangled a pendant of the Madonna at the top of his chest, somehow only served to accentuate his nakedness. And though, especially the first few days, it seemed to cost him some effort to greet even me when he saw me there in the shade of our tent; and though passing through the narrow passage between the tents and the umbrellas he never failed to furrow his brow in a show of annoyance, there was no real reason to take this performance seriously. It was clear he felt himself admired by most of those present, by the men as well as the women, and this was a source of considerable pleasure to him.
Without doubt everyone admired him, men and women alike. But it fell to Fadigati to pay for the indulgence that the Ferrarese sector of the beach at Riccione reserved for Deliliers.
Our beach-tent neighbor that year was Signora Lavezzoli, the wife of the lawyer. Having lost her former status, she is now just an old woman. But then, in the ripe splendor of her forty years, surrounded by the unstinting deference of her three adolescent children, two boys and a girl, and that, equally unstinting, of her worthy consort, the illustrious civil lawyer, university professor and ex-deputy in the Salandra camp,# she was considered one of the principal and most authoritative fonts of the city's public opinion.
Pointing her lorgnette toward the beach umbrella under which Deliliers had come to rest, Signora Lavezzoli, who had been born and raised in Pisa, "on the banks of the Arno," and made use of the exceptional skill of her quick Tuscan tongue, kept us continually abreast of everything that was happening "over there."
With the technique, almost, of a radio sports commentator, she would note for example that "the newly-weds," having just got up from their deckchairs, were wending their way toward the nearest pleasure boat: clearly the young man had expressed the desire to dive into the open sea, and "Signor Dottore," so as not to remain on his own, "in the throes of anxious passion," awaiting his return, had received permission to accompany him. Or else she described and commented on the freestyle gymnastic exercises that Deliliers, after his swim, would execute on his own, to dry himself, while "the beloved," immobile there beside him with a towel in hand, would only too willingly have offered to do the drying himself, the rubbing down, the touching...
Oh, that Deliliers—she would then add, always speaking from tent to tent, but directing her speech to my mother in particular—perhaps believing that she was lowering her voice in such a way that the "children" would not be able to hear her, though actually speaking louder than ever—that Deliliers was just a spoiled boy, a "young good-for-nothing" for whom military service might prove more than useful. But not Dr. Fadigati. For a gentleman of his standing, of his age, there was really no excuse. He was "that way"? So what—live with it! Who'd been that bothered about it anyway, until now? But to put on such an exhibition, especially here at Riccione, where he could not pretend he wasn't known, to make such a spectacle of himself; especially here when, had it been his desire, Italy could have furnished him with thousands of beaches where there'd be no danger of bumping into someone from Ferrara. Not a bit of it. Only from "a dirty old man" (and so saying, Signora Lavezzoli shot forth flames of real indignation from her queenly blue eyes), only from an "old degenerate" like him could one expect behavior of this sort.
Signora Lavezzoli talked on, and I would have given much if just once she could have kept quiet. I felt she was being unfair. Fadigati, it's true, annoyed me, but it was not by him that I found myself offended. I knew Deliliers's character perfectly. In that choice of the Romagnolo beaches, so close to Ferrara, all his malice and arrogance could be seen. Fadigati was irrelevant, I was quite certain. He was ashamed before me. If he failed to greet me, or even pretended not to see me, it was for that reason.
In contrast to the lawyer Lavezzoli, who came to the seaside the first days of August, and so along with the others was au courant regarding the scandal (inside the tent, however, while his wife held forth, he never stopped reading _Antonio Adverse_,** nor was ever heard to intervene), my father arrived in Riccione only on the morning of the 25th, a Saturday, even later than expected, and was obviously in the dark about the whole affair.
He almost immediately went up to greet Fadigati. Before my mother or the Lavezzoli family could hold him back, he was happily making his way toward him.
Fadigati winced, and turned away. My father had already
|
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"}; Hayes & Strauss, [1998](#cpp2416-bib-0018){ref-type="ref"}; Waldron, Gazzillo, Genova, & Lingiardi, [2013](#cpp2416-bib-0042){ref-type="ref"}). In addition, one study used the psychotherapy Process Q‐Sort, which specifies 100 items to describe the therapeutic interaction, for example, "therapist gives explicit advice and guidance" or "therapist remarks upon specific features of the interaction" (Jones, Cumming, & Horowitz, [1988](#cpp2416-bib-0028){ref-type="ref"}).
3.2. Therapist\'s utterances and therapy outcome {#cpp2416-sec-0016}
------------------------------------------------
Through the research question, the results can be divided into two areas with regard to outcome criteria: studies that focus on the association of the therapist\'s statements with the symptom outcome and studies that measure the therapeutic alliance.
There were eight studies relating to symptom outcome, for example, using the Beck Depression Inventory (Beck, Ward, Mendelson, Mock, & Erbaugh, [1961](#cpp2416-bib-0005){ref-type="ref"}), the Symptom Checklist‐90‐R (Derogatis, [1994](#cpp2416-bib-0010){ref-type="ref"}), or the Brief Symptom Inventory (Cunha et al., [2012](#cpp2416-bib-0008){ref-type="ref"}; Dahl et al., [2017](#cpp2416-bib-0009){ref-type="ref"}; Derogatis & Melisaratos, [1983](#cpp2416-bib-0011){ref-type="ref"}; Hayes et al., [1996](#cpp2416-bib-0017){ref-type="ref"}; Hayes & Strauss, [1998](#cpp2416-bib-0018){ref-type="ref"}; Hill et al., [1988](#cpp2416-bib-0022){ref-type="ref"}; Hoyt, Strong, Corcoran, & Robbins, [1993](#cpp2416-bib-0026){ref-type="ref"}; Jones et al., [1988](#cpp2416-bib-0028){ref-type="ref"}; Waldron et al., [2013](#cpp2416-bib-0042){ref-type="ref"}). Two articles examined the therapeutic alliance according to the Working Alliance Inventory (Horvath & Greenberg, [1989](#cpp2416-bib-0024){ref-type="ref"}; \`Golden & Robbins, [1990](#cpp2416-bib-0014){ref-type="ref"}; Watson & McMullen, [2005](#cpp2416-bib-0043){ref-type="ref"}). One study covered both target criteria (Lichtenberg et al., [1998](#cpp2416-bib-0034){ref-type="ref"}; Watson & McMullen, [2005](#cpp2416-bib-0043){ref-type="ref"}).
Considering the overall associations of the therapist\'s statements on the symptom outcome of the patient, the empirical results of the studies report both positive and negative correlations (Table [3](#cpp2416-tbl-0003){ref-type="table"}).
######
Overview of positive and negative associations of therapist\'s statements with symptom outcome of the patient, sorted by study
Positive correlation with symptom outcome Negative correlation with symptom outcome
---------------------------------------------------------------------------------------------------------------- -----------------------------------------------------------
Approval/reassurance, restatements, questions, and reflection of feelings Challenge, interpretation, self‐disclosure, and immediacy
Open questions and paraphrasing Therapist exercises a lot of control
Clarifying, interpreting, and addressing defences present in the session and addressing intrapsychic conflicts Cognitive changes in the interpersonal context
Protecting utterances
Focus on the historical antecedents of current problems
Support and stabilizing strategies
Focus of the therapist on direct interpersonal change
Exploration of frequent patients\' experiences with their parents
Directive, supportive, and partly psychoeducative elements
Focus on the therapeutic relationship in connection with other relationships
### 3.2.1. Positive correlations with symptom outcome {#cpp2416-sec-0017}
The "exploration skills," as Cunha et al. ([2012](#cpp2416-bib-0008){ref-type="ref"}) labelled them, proved to be positive because they were applied significantly more often in good than in poor outcome cases (*r* =.78 and *r* =.83, *p* \<.05). These skills include statements such as approval/reassurance, restatements, questions in an open or closed manner, and reflection of feelings. Hill et al. ([1988](#cpp2416-bib-0022){ref-type="ref"}) also found in their study of eight patients that open questions (*r* =.65, *p* \<.10) as well as paraphrasing (*r* =.64, *p* \<.10) are significantly related to symptom reduction. Waldron et al. ([2013](#cpp2416-bib-0042){ref-type="ref"}) could show that in patients with good outcomes, significantly more frequent core analytic activities (clarifying, interpreting, addressing defences present in the session, and addressing intrapsychic conflicts) were applied by the therapist. In addition, these therapists were more warm hearted, offered more support, and promoted more self‐esteem issues of the patient. In the two single case analyses by Dahl et al. ([2017](#cpp2416-bib-0009){ref-type="ref"}), the better outcome case also showed that the therapist and patient worked in a friendly complementarity and that the therapist helped the patient achieve greater autonomy at the end of the therapy through more protecting utterances than affirming ones. Hayes and Strauss ([1998](#cpp2416-bib-0018){ref-type="ref"}), on the other hand, concluded that the therapist\'s focus on the historical antecedents of current problems of the patient significantly correlates with improvement of depressive symptoms (*r* =.44, *p* \<.01). They also found that a temporary destabilization of the patient ultimately led to a significant improvement in the symptoms (*r* =.46, *p* \<.01). Therefore, the therapist\'s support and stabilizing strategies are related to a reduction of the patient\'s self‐protective attitude and to a positive therapeutic outcome. In another study of the same sample, Hayes et al. ([1996](#cpp2416-bib-0017){ref-type="ref"}) concluded that a focus of the therapist on the direct interpersonal change of the patient correlated with better global functioning at the end of therapy (*r* =.42, *p* \<.05). Furthermore, the frequent exploration of patients\' experiences with their parents was associated with improvement in depressive symptoms (*r* =.40, *p* \<.05) and with better global functioning even 2 years after therapy (*r* =.44, *p* \<.05).
In the study by Jones et al. ([1988](#cpp2416-bib-0028){ref-type="ref"}), various therapist statements were found to have a significant effect on the success of the therapy. The results were differentiated by whether the patients had a high or low disturbance level at the beginning of therapy. Overall, some directive (*r* =.174, *p* \<.001), supportive (*r* =.138, *p* \<.01), or partly psychoeducative elements (*r* =.086, *p* \<.05; and *r* =.139, *p* \<.01) and a focus on the therapeutic relationship in connection with other relationships (*r* =.101, *p* \<.01) or on the patient\'s nonverbal behaviour correlated significantly with symptom reduction.
### 3.2.2. Negative associations with symptom outcome {#cpp2416-sec-0018}
In addition to the positive correlations of therapist statements, statements could be found that were related with the worsening of the symptoms of patients in some studies. Cunha et al. ([2012](#cpp2416-bib-0008){ref-type="ref"}) stated in their study that insight skills (challenge, interpretation, self‐disclosure, and immediacy) frequently occurred in cases that had a poor therapeutic outcome (*r* =.16 to *r* =.19, *p* \<.05). If the therapist exercises much control in the therapeutic process, especially at the end of the therapy, this can also be associated with a worse therapy result (Dahl et al., [2017](#cpp2416-bib-0009){ref-type="ref"}). The authors explain this by the fact that the autonomy of the patient is kept low by increased control of the therapist. Lichtenberg et al. ([1998](#cpp2416-bib-0034){ref-type="ref"}) also observed that patients with poorer therapy outcomes controlled the therapy process more strongly than the therapists compared with the ratio in more positive cases. In both conditions, clients maintained significantly more control than the therapists (in good outcome cases, *F* = 5.15, *p* \<.05; and in poor outcome cases, *F* = 50.37, *p* \<.001). In addition, cognitive changes in the interpersonal context (*r* = −.38, *p* \<.05) were negatively correlated
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are add-on services which add functionality and provide in-depth analysis of collected data. Examples of commonly deployed Solution Packs are:
Microsoft are continuously updating Solution Packs and a few which are in public preview are listed below:
Azure Networking Analytics which enables you to gain insight into Network Security Groups and Application Gateway logs
Capacity and Performance which enables you to view Hyper-V CPU, memory and storage utilisation
Office 365 which provides visibility into user activities as well as forensics for audit and compliance purposes
Network Performance Monitoring which offers real time monitoring of parameters such as loss and latency
System Centre Operations Manager Assessment which asses the risk of your SCOM environment
VMWare Monitoring provides the ability to explore ESXi Host logs for monitoring, deep analysis and trending
The graphic below provides an example Operations Management Suite dashboard.
Workspaces
OMS uses the concept of workspaces which is primarily an administrative boundary but is also used to collect data within an Azure region. Workspaces can be used to delegate responsibility to individual users or groups who undertake specific roles e.g. Network Team access to Network Performance Monitor.
It should be noted that workspaces are independent of each other and that data collected from each workspace cannot be viewed in another workspace. However you can link multiple workspaces to a single Microsoft Azure subscription.
Workspaces also enable the use of different license plans, for example in one workspace you might use the System Center Add On and another workspace you might use Insight & Analytics.
Data Collection
Operations Management Suite collects data on a real time basis using either in-guest agents installed on Windows or Linux, a System Center Operations Management Group which uses the SCOM management servers to forward events and performance data to Log Analytics or finally an Azure Storage Account that collects data from PaaS and IaaS services.
Logging which is data generated by the operating system or application such as event logs, IIS logs, syslogs or custom logs in the form of text files.
Performance which uses the Windows or Linux performance counters to collect data such as memory, processor and disk information
Solution specific items which provide in-depth analysis of application items
A logical overview of data collection is shown below.
Licensing
OMS can be licensed either on a pay as you go basis or on a subscription basis. You are given the choice of licensing all OMS components together as a ‘suite’ which makes the overall cost cheaper or you can pick which components you need.
Licenses are based on nodes, a node is defined as a physical computer, virtual machine or network device
Node charges are hourly and nodes that only report for a part of a month are proratared
Each node can produce up to 500MB of data per day without incurring any extra charges
OMS data retention is currently set to one month, plans to expand this to two years are in the pipeline
Final Thought
OMS is maturing as a product and integration points to on-premises environment is evolving. The ability to provide a centralised dashboard with application or vendor specific solution packs will make the product more appealing. Watch this space!PERSONALIZED STRENGTH TRAINING PROGRAM
FOR TODAY'S GOLFER
There is no sport in which one does not benefit from strength training. Golf is no exception. As important as a fundamentally sound golf swing is, it's only part of the equation. No golfer will realize what he’s truly capable of without utilizing a finely tuned, professionally designed, custom strength training program. It’s an absolute must in Golf today and has the potential to completely transform your game. From maximizing swing-speed and distance to vastly improving ball striking and accuracy, preventing injury and improving your overall health, this a program for any golfer who is serious about getting the absolute most out of their potential.
CUSTOMIZED TO YOUR INDIVIDUAL NEEDS
This is not your typical cookie cutter workout program. This is a totally custom strength and conditioning system that is 100% tailored to your individual needs. There is no guesswork here. There is a reason behind every aspect of your program, with the goal of providing you with a unique blueprint to surpass even your loftiest expectations as a golfer… and that’s exactly what you will get.
Youth to Pro
Player or coach
any age
THE ASSESSMENT
The most important part of any custom strength training program is the assessment. Without a proper assessment, it’s impossible to provide you with the program you need. Every aspect of your programs design will be based on the information and data you provide to us, via our PDG Assessment Questionnaire. From sex, age, height, weight, body type, injury history, goals, workout experience, time to commit, schedule, season, nutritional habits, supplementation and sleep patterns, to strength levels, mobility, stability, flexibility, postural alignment, bone structure, musculature, tissue quality, coordination, balance, proprioception, etc, we leave no stone unturned.
YOUR PERSONALIZED TRAINING MANUAL
Once we complete the assessment, you will receive your personalized Strength Training Manual. This manual is the foundation for your entire program. Everything you need to maximize yourself physically is contained inside of it. You will gain access to an entire online library full of exercise demonstrations, recorded in beautiful 4K resolution. You can access the library anytime, on any device, anywhere… forever. Mac or PC. Your manual also comes with weekly training splits that you can either view online or print off and take to the gym, as you follow along for each session. Your personalized manual takes all the guesswork out of the equation and simply guides you, step by step. All you have to do is follow the instructions and put in the work. It’s as simple as that.
FLEXIBLE SCHEDULING
We understand everyone’s schedule is unique and that’s exactly why our custom strength program comes with options. We include 2, 3 and 4 x week strength training options, making this resource conducive to any training schedule. In-Season or Off-Season, we have you covered!
PLAY WITHOUT PAIN
Our # 1 priority is keeping our clients healthy. If you’re not healthy you simply can’t play your best. This program will help to eliminate any pain in your game, whether it be back, shoulder, elbow or anything else. We take the time to really assess your unique situation and formulate a program that will getting you swinging pain free. Whether it be a strength deficiency, a soft tissue, mobility or instability issue, we have you covered.
DYNAMIC WARMUP ROUTINE
Compared to other sports, Golfers don’t warmup properly at all. Our Dynamic Warmup Routine is the ultimate tool to prepare your body to workout, hit the range, or play a round of golf. It’s a total-body dynamic warmup routine comprised of soft tissue, mobility, muscle and nervous system activation work. You will notice improved tissue quality, improved range of motion, far less aches and pains, and much greater resilience to injury.
FREE WEIGHT WORLD, FREE WEIGHT TRAINING
We try to keep things simple by sticking to free weight exercises. Your body doesn’t get assistance in real life, so we try to limit the use of machine assistance in the gym. Compound exercises recruit the most muscle groups, require stability, build and enhance a foundation of strength and power and save you time.
MED-BALL POWER PROGRAM
All of our custom strength programs come with integrated med-ball training exercises, that focus on developing pure explosive power. Not only are you going to get stronger, you’re going to get faster. A lot faster, resulting in more distance with every club in the bag.
MULTI-PLANE CORE STRENGTHENING PROGRAM
Core strength is massively important in generating club-head speed and staying injury free. We include a spectacular core stability and core strengthening program that targets all areas of the core including the anterior, posterior, lateral and rotary core, for complete coverage in all planes of movement.
GRIP STRENGTHENING PROGRAM
Grip strength is very important for all sports and Golf is no exception. All of our custom programs come with an integrated Grip Strengthening Program used by world long drive athletes and professional baseball players. This will increase your power and speed through impact and greatly reduce any chance of elbow and wrist issues.
TOTAL BODY STRETCHING PROGRAM
Not everyone should stretch, but if we determine stretching applies to you, this program will take you through the most effective stretches for maximizing your range of motion. You will learn exactly when to incorporate stretching and when stretching can actually be detrimental. Lastly, learn why most golfers should not not stretch their back.
POST WORKOUT PROTOCOL
Learn several key points that will help you optimize your strength gains, recovery time and mental motivation to get the most out of your training and hard work.
NUTRITION & SLEEP GUIDE
You can put in all the work in the world, but if you’re not paying attention to your nutrition and sleep, you’re never going to get the most out of your workouts. Nutrition and sleep matter… a lot. They are both massively important to energy, performance and recovery. We evaluate all aspects of your lifestyle (eating, supplementation, sleep, etc) and design a program that will improve your nutrition intake and better your sleep habits with some very easy to follow tips and methods. The goal is for you
|
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D.
Finally, let’s compare EMERALD to the Tier-1 PRACE supercomputer CURIE. CURIE was the 20th fastest supercomputer in the world in November 2013. For this comparison we will need to use a bigger benchmark, so let’s us the same one as before. It has 9x the number of lipids, but because I had to add extra water ends up being about 15x bigger at 2.1 million particles. Using 24 GPUs and 72 cores, EMERALD manages 130 ns/day. To get the same performance on CURIE requires 150 cores and ultimately CURIE tops out at 1,500 ns/day on 4,196 cores. Still, EMERALD is respectable and shows how it can serve as a useful bridge to Tier-1 and Tier-0 supercomputers. Interestingly, CURIE also has a “hybrid” partition that contains 144 nodes, each with 2 Intel Westmere processors and 2 NVIDIA M2090 Tesler GPUs. I was able to run on up to 128 GPUs with 4 OpenMP threads per MPI/GPU, making a total of 512 cores. This demonstrates that GROMACS can run on large numbers of GPU/CPUs and that such hybrid architectures are viable as supercomputers (for GROMACS at least).
So if I have a particular system I want to simulate, how many processing cores can I harness to run a single GROMACS version 4.6 job? If I only use a few then the simulation will take a long time to finish, if I use too many the cores will end up waiting for communications from other cores and so the simulation will be inefficient (and also take a long time to finish). In between is a regime where the code, in this case GROMACS, scales well. Ideally, of course, you’d like linear scaling i.e. if I run on 100 cores in parallel it is 100x faster than if I ran on just one.
The rule of thumb for GROMACS 4.6 is that it scales well until there are only ~130 atoms/core. In other words, the more atoms or beads in your system, the larger the number of computing cores you can run on before the scaling performance starts to degrade.
As you might imagine there is a hierarchy of computers we can run our simulations on; this starts at humble workstations, passes through departmental, university and regional computing clusters before ending up at national (Tier 1) and international (Tier 0) high performance computers (HPC).
In our lab we applied for, and got access to, a set of European Tier 0 supercomputers through PRACE. These are currently amongst the fastest and largest supercomputers in the world. We tested five supercomputers in all: CURIE (Paris, France; green lines), MareNostrum (Barcelona, Spain; black line), FERMI (Bologna, Italy; lilac), SuperMUC (Munich, Germany; blue) and HERMIT (Stuttgart, Germany; red ). Each has a different architecture and inevitably some are slightly newer than others. CURIE has three different partitions, called thin, fat and hybrid. The thin nodes constitute the bulk of the system; the fat nodes have more cores per node whilst the hybrid nodes combine conventional CPUs with GPUs.
We tested a coarse-grained 54,000 lipid bilayer (2.1 million MARTINI beads) on all seven different architectures and the performance is shown in the graph – note that the axes are logarithmic. Some machines did better than others; FERMI, which is an IBM BlueGene/Q, appears not to be well-suited to our benchmark system, but then one doesn’t expect fast per-core performance on a BlueGene as that is not how they are designed. Of the others, MareNostrum was fastest for small numbers of cores, but its performance began to suffer if more than 256 cores were used. SuperMUC and the Curie thin nodes were the fastest conventional supercomputers, with the Curie thin nodes performing better at large core counts. Interestingly, the Curie hybrid GPU nodes were very fast, especially bearing in mind the CPUs on these nodes are older and slower than those in the thin nodes. One innovation introduced into GROMACS 4.6 that I haven’t discussed previously is one can now run either using purely MPI processes or a combination of MPI processes and OpenMP threads. We were somewhat surprised to find, that, in nearly all cases, the pure MPI approach remained slightly faster than the new hybrid parallelisation.
Of course, you may see very different performance using your system with GROMACS 4.6. You just have to try and see what you get! In the next post I will show some detailed results on using GROMACS on GPUs.
GROMACS is a scientific code designed to simulate the dynamics of small boxes of stuff, that usually contain a protein, water, perhaps a lipid bilayer and a range of other molecules depending on the study. It assumes that all the atoms can be represented as points with a mass and an electrical charge and that all the bonds can modelled using simple harmonic springs. There are some other terms that describe the bending and twisting of molecules and all of these, when combined with two long range terms, which take into account the repulsion and attraction between electrical charges, allow you to calculate the force on any atom due to the positions of all the other atoms. Once you know the force, you can calculate where the atom will be a short time later (often 2 fs) but of course the positions have changed so you have to recalculate the forces. And so on.
Anyway, I use GROMACS a lot in my research and the most recent major version, 4.6, was released in January 2012. In this post I’m going to briefly describe my experience with some of the improvements. First off, so much has changed that I think it would have been more accurate to call this GROMACS 5.0. For example, version 4.6 is a lot faster than version 4.5. I typically use three different benchmarks when measuring the performance; one is an all-atom simulation of a bacterial peptide transporter in a lipid bilayer (78,033 atoms). The other two are both coarse-grained models of a lipid bilayer using the MARTINI forcefield – the difference is one has 6,000 lipids (137,232 beads), the other 54,000 (2,107,010 beads). Ok, so how much faster is version 4.6? It is important here to bear in mind that GROMACS was already very fast since a lot of effort had been put into optimising the loops that the code spends most of its time running. Even so, version 4.6 is between 20-120% faster when using either of the first two benchmarks, and in some cases even faster. How? Well, it seems the developers have completely re-written those loops using SIMD commands. One important consequence of this is that it is vital to use the best compiler and, since you have to specify which SIMD instruction sets to use, you may need several different versions of the key binary, mdrun. For example, you may want a version compiled using AVX SIMD instruction sets for recent CPUs, but also a version compiled using an older SSE SIMD instruction set. The latter will run on newer architectures, but it will be slower. You must never run a version compiled with no SIMD instruction sets as this can be 10x slower!
The other big performance improvement is that GROMACS 4.6 now uses GPUs seamlessly. The calculations are shared between any GPUs and the CPUs and GROMACS will even shift the load to try and share it equally. Erik Landahl, one of the GROMACS developers, gave an interesting NVIDA webinar on this subject in April 2013. A GPU here just means a reasonable consumer graphics card, such as an NVIDIA GTX680, that has compute capability of 2.0 or higher. So, how much performance boost do we see? I typically see a boost of 2.1-2.7x for the atomistic benchmark and 1.4-2.2x for the first, smaller coarse-grained benchmark. Just for fun, you can try running a version of GROMACS compiled with no SIMD instructions with a GPU (and without a GPU) and then you can get a performance increase of 10x.
Before I finish, I was given some good advice on running GROMACS benchmarks. Firstly, make sure you use the -noconfout mdrun option since this prevents it from writing a final.gro file as this takes some time. Secondly setup a.tpr file that will run for a long (wallclock) time even on a large number of cores and then use the -resethway option in combination with a time limit, such as -maxh 0.25, as this would then reset the timers after 7.5 min and record how many steps were calculated between 7.5 and 15 minutes. From experience a bit of time spent writing some good BASH scripts to automatically setup, run and analyse the benchmarking simulations really pays off in the long run.
In future posts I’ll talk about the scaling of GROMACS 4.6 (that is where the third benchmark comes in) and also look at the GPU performance in a bit more detail.If you look for shopping applications, you must get plethora applications available. It is very east to get. But, there is a unique application named Listia. Listia is an application that allows you to get a thing or give a thing to somebody else. Usually the things given or taken are used
|
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] |
Current at the time of the band’s reunion shows. “His lyrics and music are absolutely astounding.”
“Willie was one of a kind. One of the best. One for the ages,” Curtiss A wrote on Facebook.
“The Triangle. The Union. The 400. The Viking. Thanks for the memories Willie. You outlasted them all,” veteran local music fan Gregory Ide posted on Facebook.
Sad though his passing may be, Murphy’s fans got to say an unintended goodbye—at a listening party for Dirtball at the Minneapolis Eagles Club #34 in November. “It was a great success, there were a lot of people there,” Murphy told City Pages in December. “Remarkably, I felt pretty good that night. Tons of people. No band playing, we just played Dirtball and in between we played some of my older records. There was just so much love.”Processing 1.0
Processing 1.0 has arrived. Lots of people have posted on this. I don’t know if that means that mobile processing is out of beta as well. Perhaps I should do some digging around. Here’s the first part of the press release:
We’ve just posted Processing 1.0 at http://processing.org/download. We’re so excited about it, we even took time to write a press release.
CAMBRIDGE, Mass. and LOS ANGELES, Calif. – November 24, 2008 – The Processing project today announced the immediate availability of the Processing 1.0 product family, the highly anticipated release of industry-leading design and development software for virtually every creative workflow. Delivering radical breakthroughs in workflow efficiency – and packed with hundreds of innovative, time-saving features – the new Processing 1.0 product line advances the creative process across print, Web, interactive, film, video and mobile.
Whups! That’s not the right one. Here we go:
Today, on November 24, 2008, we launch the 1.0 version of the Processing software. Processing is a programming language, development environment, and online community that since 2001 has promoted software literacy within the visual arts. Initially created to serve as a software sketchbook and to teach fundamentals of computer programming within a visual context, Processing quickly developed into a tool for creating finished professional work as well.
Processing is a free, open source alternative to proprietary software tools with expensive licenses, making it accessible to schools and individual students. Its open source status encourages the community participation and collaboration that is vital to Processing’s growth. Contributors share programs, contribute code, answer questions in the discussion forum, and build libraries to extend the possibilities of the software. The Processing community has written over seventy libraries to facilitate computer vision, data visualization, music, networking, and electronics.india
Updated: Nov 20, 2019 01:49 IST
Rajya Sabha was adjourned for about three hours till 2 pm on Tuesday amid uproar by Opposition parties, including the Left and Congress, over the alleged police action against Jawaharlal Nehru University students protesting against a fee hike and the detention of political leaders in Jammu and Kashmir.
There was chaos in the Upper House soon after it mourned the death of former Zimbabwean president Robert Mugabe and congratulated Abhijeet Banerjee for winner the Nobel prize for economics, with the Opposition raising the issues related to JNU and J&K.
Three members had given a notice for suspension of business to raise these issues but Chairman M Venkaiah Naidu refused. “It has been a practice not to allow discussion under Rule 267 and disturb the House. I am not going to allow it...,” Naidu said before adjourning the house till 2 pm.
JNU students, who have been protesting since October 30, took out a march to Parliament on Monday to raise their demands on the opening day of the Winter Session. Hundreds of students faced off with the Delhi Police after they were intercepted in Jorbagh and outside the university campus. In J&K, all top political leaders, including three former CMs, have been under detention since August 5 to pre-empt a law and order situation after the abrogation of Article 370.
TMC member Derek O’Brien questioned the decision of adjournment on Twitter. “Not a single MP from Opposition went into the Well of the Rajya Sabha. Yet, House was adjourned within minutes right till 2 pm. Oppn deprived of raising imp issues in Zero Hour...” he tweeted.using System;
using System.Collections.Generic;
using System.IdentityModel.Tokens.Jwt;
using System.Linq;
using System.Text;
using System.Threading.Tasks;
namespace PnP.PowerShell.Commands.Utilities
{
internal static class JwtUtility
{
public static bool HasScope(string accessToken, string scope)
{
var handler = new JwtSecurityTokenHandler();
var token = handler.ReadJwtToken(accessToken);
var scpClaims = token.Claims.Where(c => c.Type == "scp");
var roleClaims = token.Claims.Where(c => c.Type == "roles");
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In the early days of his presidency, Barack Obama declared his commitment to “seek the peace and security of a world without nuclear weapons.” Now, six years later, Obama’s Pentagon is kick-starting a massive effort to revamp its doomsday arsenal—building all sorts of new weapons that Obama once said he didn’t want.
Under the Pentagon’s new budget proposal—which is still subject to congressional approval—the Defense Department would accelerate the development of a new nuclear-tipped cruise missile, modernize its ballistic missiles, and continue to invest in new ballistic missile submarines and new, nuclear-capable stealth bombers.
“Our nuclear deterrent force is aging. It will be modernized in the 2020s and 2030s,” deputy defense secretary Bob Work told reporters at the Pentagon this week. “We need to keep the old equipment and systems going, but it is becoming more expensive for us to do so and requiring us to divert resources in that regard.”
The Arms Control Association’s Kingston Reif later called the new president’s proposed budget the “biggest down payment to date on a planned unaffordable and unsustainable nuclear spending binge.” Reif noted that Obama—who had promised to work toward ridding the world of nuclear weapons—would preside over a massive rebuilding of the American nuclear weapons complex.
“Part of President Barack Obama’s legacy on nuclear weapons will now be as the president who set in motion plans to remake a nuclear arsenal like the one the United States has today for decades to come,” Reif wrote.
One of the most notable instances where the Obama administration has adopted a more aggressive posture in on the new Long-Range Standoff (LRSO) cruise missile, which the new budget accelerates by two years. The weapons should enter service in 2028, based on the previous schedule for the missile. (The latest budget doesn’t actually say when the LRSO is supposed to become operational.)
The Pentagon has budgeted for $36.6 million for early development work on the new LRSO weapon—a nuclear-tipped cruise missile, designed to replace the current weapon that is mounted on the B-52.
The current Air Launched Cruise Missile is increasing vulnerable to enemy air defenses—and the Air Force is running out the weapons. Many of those old cruise missiles have had their nuclear warheads removed and have been armed with conventional explosives. The new weapon is designed to punch through the toughest of enemy air defenses; Russia’s, for example. “The LRSO weapon system will be capable of penetrating and surviving advanced Integrated Air Defense Systems from significant stand-off range to prosecute strategic targets,” the budget document reads.
Meanwhile, the Air Force is continuing on its quest to develop a super stealthy new bomber called the Long-Range Strike-Bomber (LRS-B) for $550 million each that would be flying by the mid-2020s that will carry the LRSO missile. The Air Force won’t say much about the new bomber except that it will be extremely stealthy, subsonic, and that it will be nuclear capable in time. “The LRS-B aircraft must be able to penetrate highly contested environments, have top-end low observability characteristics, and loiter capability,” the budget documents state.
Given the stealth requirement, the plane is almost certainly going to be a flying wing similar in concept to the $2.2 billion Northrop Grumman B-2 Spirit stealth bomber.
The LRS-B bomber program is slated to receive $1.2 billion in the 2016 budget proposal. Either Northrop Grumman or a Boeing/Lockheed Martin team will win the contract to build the new bomber—which is going
|
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] |
.comGameBook!! rowspan="2" | NFL.comRecap
|-
! Final score!! Team record
|- style="background:#cfc"
! style="background:#03202F; color:white; text-align:center;"| 1
|style="text-align:center;"| September 11
|style="text-align:center;"| 12:00 p.m.
|style="text-align:center;"| Atlanta Falcons§
|style="text-align:center;"| W 30–12
|style="text-align:center;"| 1–0
|style="text-align:center;"| Soldier Field
|style="text-align:center;"| Fox
|style="text-align:center;"| Gamebook
|style="text-align:center;"| Recap
|- style="background:#fcc"
! style="background:#03202F; color:white; text-align:center;"| 2
|style="text-align:center;"| September 18
|style="text-align:center;"| 12:00 p.m.
|style="text-align:center;"| at New Orleans Saints§
|style="text-align:center;"| L 13–30
|style="text-align:center;"| 1–1
|style="text-align:center;"| Louisiana Superdome
|style="text-align:center;"| Fox
|style="text-align:center;"| Gamebook
|style="text-align:center;"| Recap
|- style="background:#fcc"
! style="background:#df6108; color:white; text-align:center;"| 3
|style="text-align:center;"| September 25
|style="text-align:center;"| 3:15 p.m.
|style="text-align:center;"| Green Bay Packers†
|style="text-align:center;"| L 17–27
|style="text-align:center;"| 1–2
|style="text-align:center;"| Soldier Field
|style="text-align:center;"| Fox
|style="text-align:center;"| Gamebook
|style="text-align:center;"| Recap
|- style="background:#cfc"
! style="background:#03202F; color:white; text-align:center;"| 4
|style="text-align:center;"| October 2
|style="text-align:center;"| 12:00 p.m.
|style="text-align:center;"| Carolina Panthers§
|style="text-align:center;"| W 34–29
|style="text-align:center;"| 2–2
|style="text-align:center;"| Soldier Field
|style="text-align:center;"| Fox
|style="text-align:center;"| Gamebook
|style="text-align:center;"| Recap
|- style="background:#fcc"
! style="background:white; color:#03202F; text-align:center;"| 5
|style="text-align:center;"| October 10
|style="text-align:center;"| 7:30 p.m.
|style="text-align:center;"| at Detroit Lions†
|style="text-align:center;"| L 13–24
|style="text-align:center;"| 2–3
|style="text-align:center;"| Ford Field
|style="text-align:center;"| ESPN
|style="text-align:center;"| Gamebook
|style="text-align:center;"| Recap
|- style="background:#cfc"
! style="background:#03202F; color:white; text-align:center;"| 6
|style="text-align:center;"| October 16
|style="text-align:center;"| 7:20 p.m.
|style="text-align:center;"| Minnesota Vikings†
|style="text-align:center;"| W 39–10
|style="text-align:center;"| 3–3
|style="text-align:center;"| Soldier Field
|style="text-align:center;"| NBC
|style="text-align:center;"| Gamebook
|style="text-align:center;"| Recap
|- style="background:#cfc"
! style="background:white; color:#03202F; text-align:center;"| 7
|style="text-align:center;"| October 23
|style="text-align:center;"| 12:00 p.m.
|style="text-align:center;"| at Tampa Bay Buccaneers§
|style="text-align:center;"| W 24–18
|style="text-align:center;"| 4–3
|style="background:red; color:white; border:2px solid blue; text-align:center;"| Wembley Stadium (London)^
|style="text-align:center;"| Fox
|style="text-align:center;"| Gamebook
|style="text-align:center;"| Recap
|-
! 8
|colspan="9" style="text-align:center;"| Bye|- style="background:#cfc"
! style="background:white; color:#03202F; text-align:center;"| 9
|style="text-align:center;"| November 7
|style="text-align:center;"| 7:30 p.m.
|style="text-align:center;"| at Philadelphia Eagles§
|style="text-align:center;"| W 30–24
|style="text-align:center;"| 5–3
|style="text-align:center;"| Lincoln Financial Field
|style="text-align:center;"| ESPN
|style="text-align:center;"| Gamebook
|style="text-align:center;"| Recap
|- style="background:#cfc"
! style="background:#df6108; color:white; text-align:center;"| 10
|style="text-align:center;"| November 13
|style="text-align:center;"| 3:15 p.m.
|style="text-align:center;"| Detroit Lions†
|style="text-align:center;"| W 37–13
|style="text-align:center;"| 6–3
|style="text-align:center;"| Soldier Field
|style="text-align:center;"| Fox
|style="text-align:center;"| Gamebook
|style="text-align:center;"| Recap
|- style="background:#cfc"
! style="background:#03202F; color:white; text-align:center;"| 11
|style="text-align:center;"| November 20
|style="text-align:center;"| 3:15 p.m.
|style="text-align:center;"| San Diego Chargers≈
|style="text-align:center;"| W 31–20
|style="text-align:center;"| 7–3
|style="text-align:center;"| Soldier Field
|style="text-align:center;"| CBS
|style="text-align:center;"| Gamebook
|style="text-align:center;"| Recap
|- style="background:#fcc"
! style="background:white; color:#03202F; text-align:center;"| 12
|style="text-align:center;"| November 27
|style="text-align:center;"| 3:05 p.m.
|style="text-align:center;"| at Oakland Raiders≈
|style="text-align:center;"| L 20–25
|style="text-align:center;"| 7–4
|style="text-align:center;"| O.co Coliseum
|style="text-align:center;"| Fox
|style="text-align:center;"| Gamebook
|style="text-align:center;"| Recap
|- style="background:#fcc"
! style="background:#03202F; color:white; text-align:center;"| 13
|style="text-align:center;"| December 4
|style="text-align:center;"| 12:00 p.m.
|style="text-align:center;"| Kansas City Chiefs≈
|style="text-align:center;"| L 3–10
|style="text-align:center;"| 7–5
|style="text-align:center;"| Soldier Field
|style="text-align:center;"| CBS
|style="text-align:center;"| Gamebook
|style="text-align:center;"| Recap
|- style="background:#fcc"
! style="background:white; color:#03202F; text-align:center;"| 14
|style="text-align:center;"| December 11
|style="text-align:center;"| 3:05 p.m.
|
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Delta_{(0,\frac12)}}(\bar z)
\\
+ D_{(2,\frac12)} \Big(\mathcal{F}^{(s)}_{\Delta_{(2,-\frac12)}}(z)\mathcal{F}^{(s)}_{\Delta_{(2,\frac12)}}(\bar z) + \mathcal{F}^{(s)}_{\Delta_{(2,\frac12)}}(z)\mathcal{F}^{(s)}_{\Delta_{(2,-\frac12)}}(\bar z)\Big) +O(Q)\.\end{gathered}$$ More explicitly, this is $$\begin{aligned}
R_2 \ \underset{Q\to 0}{=}\ \frac12 + \frac{1}{16\pi} \sqrt{Q} \Big(\log(1-z) +\log(1-\bar z) \Big) + O(\sqrt{Q})\.\end{aligned}$$ We are now neglecting $O(\sqrt{Q})$ terms from the expansions of $D_{(0,\frac12)}$ and of the block $\mathcal{F}^{(s)}_{\Delta_{(0,\frac12)}}(z)$. Such terms are not easy to compute, and it is clear that the block has a logarithmic singularity at $z=0$ at this order. Neglecting these terms however does not make our $O(\sqrt{Q})$ terms from the $(2,\frac12)$ channel meaningless, because it is the $(2,\frac12)$ channel that dominates in differences of correlation functions, for example $$\begin{aligned}
R_2 -R_3\ \underset{Q\to 0}{=}\ \frac{1}{8\pi} \sqrt{Q} \Big(\log(1-z) +\log(1-\bar z) \Big) + O(Q)\.\end{aligned}$$ Comparing with equations and for the behaviour of connectivities, we find that the relation between connectivities and correlation functions exactly holds at $Q=0$.
Q=2,3,4: spin correlation functions {#magneticcorr}
-----------------------------------
For $Q=2,3,4$, the Potts model can be defined in terms of spins $s(x)$, sitting at each lattice site $x$ and taking $Q$ values, $s(x)=1,\dots,Q$. The partition function is $$\begin{aligned}
\label{Potts_pf}
\mathcal{Z}=\prod_{\langle x, y\rangle}\exp{\left[-J\delta_{s(x),s(y)}\right]}\,\end{aligned}$$ where the product is over pairs of neighbouring sites. The model is invariant under permutations of the $Q$ values of the spins. It has a critical point at $$\begin{aligned}
\label{Jc}
J_c(Q)=\log \left(1+\sqrt{Q}\right)\,\end{aligned}$$ which separates a ferromagnetic phase from a paramagnetic phase. We introduct the spin observables $$\begin{aligned}
\label{orderparam}
\sigma_{\alpha}(x)=Q\delta_{s(x),\alpha}-1 \quad \text{where}\quad \left(\alpha = 1,\dots, Q\right)\,\end{aligned}$$ which obey the relation $\sum_{\alpha=1}^{Q}\sigma_{\alpha}(x)=0$. This relation, and permutation symmetry, lead to linear relations between correlators of spin observables. Modulo such linear relations, all two- and three-point functions are proportional to two- and three-point functions of the type $\left<\sigma_\alpha \sigma_\alpha\right>$ and $\left<\sigma_\alpha \sigma_\alpha \sigma_\alpha\right>$, where the latter actually vanishes in the case $Q=2$. Furthermore, correlators of spin observables can be expressed in terms of cluster connectivities. In the case of two- and three-point functions, the relations are $$\begin{aligned}
\label{2ptconn}
\langle \sigma_{\alpha}\sigma_{\alpha} \rangle &=(Q-1) p_{12}\,
\\
\label{3ptconn}
\langle \sigma_{\alpha}\sigma_{\alpha} \sigma_{\alpha}\rangle &=(Q-1)(Q-2) p_{123}\.\end{aligned}$$ All four-point functions are linear combinations of the four basic functions $\left<\sigma_\alpha\sigma_\alpha\sigma_\alpha\sigma_\alpha\right>$, $\left<\sigma_\beta\sigma_\beta\sigma_\alpha\sigma_\alpha\right>$, $\left<\sigma_\beta\sigma_\alpha\sigma_\beta\sigma_\alpha\right>$, $\left<\sigma_\beta\sigma_\alpha\sigma_\alpha\sigma_\beta\right>$ with $\beta\neq \alpha$. The expressions of these basic four-point functions as linear combinations of the cluster connectivities can be found in [@DeViconn]. Let us write these expressions in the cases $Q=2,3,4$.
For $Q=2$, our four basic four-point functions are all equal since $\sigma_2=-\sigma_1$, and the relation with connectivities is $$\begin{aligned}
\label{q2mag}
\left<\sigma_1\sigma_1\sigma_1\sigma_1\right> = p_{1234}+p_{12,34}+p_{13,24}+p_{14,23}\.\end{aligned}$$ For $Q=3$, it is convenient to use the basis of operators $\{\omega_1,\omega_2\}$ such that $$\begin{aligned}
\sigma_1 = e^{\frac{2\pi i}{3}} \omega_1 + e^{\frac{4\pi i}{3}} \omega_2 \quad, \quad \sigma_2 = e^{\frac{4\pi i}{3}} \omega_1 + e^{\frac{2\pi i}{3}} \omega_2 \quad,\quad \sigma_3=\omega_1+\omega_2\.
\label{Q3sigma}\end{aligned}$$ In terms of these operators, permutations of $\sigma_\alpha$ are generated by the permutation $\omega_1\leftrightarrow \omega_2$, and the $\mathbb{Z}_3$ action $$\begin{aligned}
\label{omegatransf}
\omega_{\alpha} \to e^{\frac{2\pi i}{3}\alpha}\omega_{\alpha} \.\end{aligned}$$ At the level of four-point functions, the change of bases reads $$\begin{aligned}
\left<\sigma_\alpha\sigma_\alpha\sigma_\alpha\sigma_\alpha\right> &= 2\left<\omega_1\omega_1\omega_2\omega_2\right>+2\left<\omega_1\omega_2\omega_1\omega_2\right>+2\left<\omega_1\omega_2\omega_2\omega_1\right>\,
\label{4s3p}
\\
\left<\sigma_\beta\sigma_\beta\sigma_\alpha\sigma_\alpha\right> &= -\left<\omega_1\omega_1\omega_2\omega_2\right>+2\left<\omega_1\omega_2\omega_1\omega_2\right>+2\left<\omega_1\omega_2\omega_2\omega_1\right>\.\end{aligned}$$ Due to the $\mathbb{Z}_3$ symmetry and the symmetry under $\omega_1\leftrightarrow \omega_2$, the three correlators that appear here form a basis of four-point correlators of $\omega_1,\omega_2$. Their relations with connectivities are $$\begin{aligned}
\langle \omega_{1}\omega_{1}\omega_{2}\omega_{2}\rangle &= p_{1234}+p_{13,24}+p_{14,23} \label{q3wP}\, \\
\langle \omega_{1}\omega_{2}\omega_{1}\omega_{2}\rangle &= p_{1234}+p_{12,34}+p_{14,23} \label{q3wPb}\, \\
\langle \omega_{1}\omega_{2}\omega_{2}\omega_{1}\rangle &= p_{1234}+p_{12,34} +p_{13,24}\label{q3wPc}\.
\end{aligned}$$ For $Q=4$, it is convenient to introduce yet another basis of operators: the spins $\tau_1$ and $\tau_2$ of two Ising models, which are coupled in the Ashkin–Teller model, which is itself equivalent to the $Q=4$ Potts model. In terms of these spins, the partition function reads [@SaleurAT] $$\begin{aligned}
\label{AT}
\mathcal{Z}= \sum_{\left<x,y\right>} e^{K_2 \left[\tau_1 (x)\tau_1 (y)+\tau_2 (x)\tau_2 (y)\right] + K_4 \left[\tau_1 (x)\tau_1 (y)\tau_2 (x)\tau_2 (y)\right]}\.\end{aligned}$$ This model is critical for $e^{-2K_4}=\sinh{2 K_2}$, with the $Q=4$ Potts model corresponding to the case $K_2=K_4=\frac{J_c(4)}{
|
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