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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/consensus.joblib +3 -0
  4. interpro_active_site/df_merge.tsv +1 -0
  5. interpro_active_site/metrics.json +7 -0
  6. interpro_active_site/paths.json +1 -0
  7. interpro_active_site/result.tsv +6 -0
  8. interpro_active_site/selections.json +1 -0
  9. interpro_binding_site/advanced/idx2term.json +1 -0
  10. interpro_binding_site/basic/idx2term.json +1 -0
  11. interpro_binding_site/basic/plot_0.png +3 -0
  12. interpro_binding_site/consensus.joblib +3 -0
  13. interpro_binding_site/df_merge.tsv +1 -0
  14. interpro_binding_site/metrics.json +7 -0
  15. interpro_binding_site/paths.json +1 -0
  16. interpro_binding_site/result.tsv +6 -0
  17. interpro_binding_site/selections.json +1 -0
  18. interpro_conserved_site/advanced/idx2term.json +1 -0
  19. interpro_conserved_site/basic/idx2term.json +1 -0
  20. interpro_conserved_site/basic/plot_0.png +3 -0
  21. interpro_conserved_site/basic/plot_1.png +3 -0
  22. interpro_conserved_site/consensus.joblib +3 -0
  23. interpro_conserved_site/df_merge.tsv +3 -0
  24. interpro_conserved_site/metrics.json +7 -0
  25. interpro_conserved_site/paths.json +1 -0
  26. interpro_conserved_site/result.tsv +45 -0
  27. interpro_conserved_site/selections.json +1 -0
  28. interpro_domain/advanced/idx2term.json +1 -0
  29. interpro_domain/advanced/plot_0.png +3 -0
  30. interpro_domain/basic/idx2term.json +1 -0
  31. interpro_domain/basic/plot_0.png +3 -0
  32. interpro_domain/basic/plot_1.png +3 -0
  33. interpro_domain/basic/plot_10.png +3 -0
  34. interpro_domain/basic/plot_11.png +3 -0
  35. interpro_domain/basic/plot_12.png +3 -0
  36. interpro_domain/basic/plot_2.png +3 -0
  37. interpro_domain/basic/plot_3.png +3 -0
  38. interpro_domain/basic/plot_4.png +3 -0
  39. interpro_domain/basic/plot_5.png +3 -0
  40. interpro_domain/basic/plot_6.png +3 -0
  41. interpro_domain/basic/plot_7.png +3 -0
  42. interpro_domain/basic/plot_8.png +3 -0
  43. interpro_domain/basic/plot_9.png +3 -0
  44. interpro_domain/consensus.joblib +3 -0
  45. interpro_domain/df_merge.tsv +9 -0
  46. interpro_domain/metrics.json +7 -0
  47. interpro_domain/paths.json +1 -0
  48. interpro_domain/result.tsv +291 -0
  49. interpro_domain/selections.json +0 -0
  50. interpro_family/advanced/idx2term.json +1 -0
interpro_active_site/advanced/idx2term.json ADDED
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+ {}
interpro_active_site/basic/idx2term.json ADDED
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interpro_active_site/consensus.joblib ADDED
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interpro_active_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3430,
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+ "annotations_size": 55,
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+ "title": "Average number of proteins per term",
6
+ "value": 3.0
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+ }
interpro_active_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C002/C002_val_log2fc"}
interpro_active_site/result.tsv ADDED
@@ -0,0 +1,6 @@
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003] 0.5988756816796552 0.8888108898902624 0.3741047222923741 0.9999999999935792 0.9563037006485128 4 P06576 1
3
+ Protein-tyrosine phosphatase, active site [IPR016130] 0.5258794922643802 0.8499345624524316 0.3953614685555953 0.99999999999904 0.9563037006485128 7 Q9H3S7,P10586 2
4
+ Peptidase family C14A, cysteine active site [IPR033139] 0.6887397899650001 0.4327046559098759 0.6652293469351469 1.0 0.9563037006485128 2 P42574 1
5
+ Peptidase family C14A, His active site [IPR016129] 0.6887397899650001 0.4327046559098759 0.6652293469351469 1.0 0.9563037006485128 2 P42574 1
6
+ ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440] 0.4019836639439907 0.0305914438358375 0.9755953657877234 1.0 0.991796362964252 2 P53396 1
interpro_active_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA/RNA non-specific endonuclease, active site [IPR018524]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "BUB1", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CASP7", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CHEK1", "CHEK2", "CHUK", "CIT", "CKB", "CKMT1A*", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "ENDOG", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "IRAK1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR2", "MTMR6", "NEK9", "NME1", "NME3", "OXCT1", "OXSM", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRPF4B", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RAF1", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SGK3", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE2T", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["ACLY", "ATP5B", "CASP3", "PTPN23", "PTPRF"]}
interpro_binding_site/advanced/idx2term.json ADDED
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interpro_binding_site/basic/idx2term.json ADDED
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+ {"0": "EF-Hand 1, calcium-binding site [IPR018247]"}
interpro_binding_site/basic/plot_0.png ADDED

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interpro_binding_site/df_merge.tsv ADDED
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interpro_binding_site/metrics.json ADDED
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+ {
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+ "title": "Average number of proteins per term",
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interpro_binding_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C002/C002_val_log2fc"}
interpro_binding_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Peptidase M16, zinc-binding site [IPR001431] 0.6391116102653611 1.183134719568853 0.2367557597461707 0.999769553771766 0.7688912498093717 5 Q10713,O75439 2
3
+ Hexokinase, binding site [IPR019807] 0.7424154025670804 0.5940769700475008 0.5524606334501816 0.9999999999850112 0.9431703785456084 2 P52789 1
4
+ Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.7138273045507414 0.5056139626416377 0.6131276777480037 0.999999999999836 0.9431703785456084 2 P34897 1
5
+ EF-Hand 1, calcium-binding site [IPR018247] 0.4658976560670991 0.1684821731087625 0.8662039669964057 1.0 0.9431703785456084 41 Q14257,Q9BRK5,Q96AY3,P80303,Q9NWM8,Q9Y680,P43304,Q02818,P14314,O43852,O95302 11
6
+ Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838] 0.4897899649941812 0.0712856968280129 0.9431703785456084 1.0 0.9431703785456084 2 P17174 1
interpro_binding_site/selections.json ADDED
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+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "ARG2", "AURKA", "AURKB", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CEP97", "CETN2", "CHEK1", "CHUK", "CIT", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MARK2", "MCCC1", "METAP2", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RAF1", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SGK3", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK4", "TAOK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "USP32", "VRK1", "YES1"], "leading_proteins": ["CALU", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GOT1", "GPD2", "HK2", "NUCB1", "NUCB2", "PMPCA", "PMPCB", "PRKCSH", "RCN2", "SDF4", "SHMT2"]}
interpro_conserved_site/advanced/idx2term.json ADDED
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interpro_conserved_site/basic/idx2term.json ADDED
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interpro_conserved_site/basic/plot_0.png ADDED

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interpro_conserved_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
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+ Proteasome beta-type subunit, conserved site [IPR016050] 4 8 2.256721297884761 0.0240254951725622 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 1.0 0.0921025797166938 0.0231366382468947 5.489393781591606e-05
3
+ Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 3 6 2.077156724470388 0.037787096552984 2.3592233009708736 5.065533980582524 -0.0414779785270424 0.5135274314368297 1.4687975990686668 1.3840549880732227 1.041360968799742 0.3265718594638703 1.0 1.0 1.0 1.0 0.0027834726260547
interpro_conserved_site/metrics.json ADDED
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3430,
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+ "annotations_size": 279,
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+ "title": "Average number of proteins per term",
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+ "value": 2.795698924731183
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+ }
interpro_conserved_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C002/C002_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.8413291105499114 2.2567212978847615 0.0240254951725622 0.9988693350734066 0.6303249152555013 8 P28074,P28070,P49721,P20618 4
3
+ Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.7908861083633023 2.077156724470388 0.037787096552984 0.9999784891157346 0.6303249152555013 6 Q13535,P42345,Q13315 3
4
+ Acyl-CoA dehydrogenase, conserved site [IPR006089] 0.7471963346476739 1.8842243547974773 0.0595346345272336 0.999999963470562 0.6303249152555013 6 Q9H845,P26440,P11310 3
5
+ Thioredoxin, conserved site [IPR017937] 0.7480653991506676 1.811677115120033 0.0700361016950557 0.9999999984076484 0.6303249152555013 10 Q9H3N1,Q9H1E5,P13667,P07237,O95881,Q15084,Q8IXB1,P30101 8
6
+ 3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.8335101654749797 1.5830333856209269 0.1134138551516228 0.9999999999999974 0.680091426908633 3 Q16836 1
7
+ Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412] 0.698655625387383 1.5151933263278112 0.129723452652247 1.0 0.6905903541280545 14 Q9NSE4,Q5JPH6,Q5T160,P47897 4
8
+ ABC transporter-like, conserved site [IPR017871] 0.6705270606551084 1.4243035841079643 0.154358610439548 1.0 0.6905903541280545 12 Q03519,P08183,P61221,Q9NUT2,Q03518,O75027 6
9
+ Haem oxygenase conserved site [IPR018207] 0.9708284714118992 1.4100483969511433 0.1585253928874332 1.0 0.6905903541280545 2 P30519 1
10
+ 4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.7826086956521627 1.3810473146995934 0.1672644131974103 1.0 0.6905903541280545 3 O00217,P21912 2
11
+ Enoyl-CoA hydratase/isomerase, conserved site [IPR018376] 0.6135566496132963 1.273584875386495 0.2028105751979012 1.0 0.738638246953844 6 P40939 1
12
+ Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.6439494196168543 1.2039915406565087 0.2285928481768739 1.0 0.7652665863714265 5 P48735,P50213,P51553 3
13
+ Procollagen-lysine 5-dioxygenase, conserved site [IPR001006] 0.726750740855783 1.1589321981386271 0.2464838231960999 1.0 0.7789569568931429 3 O60568 1
14
+ Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.5824653977037315 1.0924180998706832 0.274649370925192 1.0 0.7801448521373215 8 P30837,P51649,P30038,P51648 4
15
+ Macrophage migration inhibitory factor, conserved site [IPR019829] 0.8576429404900688 0.9906640861651428 0.3218496332211731 1.0 0.8189704353387081 2 P14174 1
16
+ HMG box A DNA-binding domain, conserved site [IPR017967] 0.6682229355121078 0.9288264458686036 0.3529790367221237 1.0 0.8226929640589856 3 O15347,P09429 2
17
+ Ribosomal protein L3, conserved site [IPR019926] 0.8389731621937009 0.9233386849122044 0.3558307339674811 1.0 0.8226929640589856 2 P09001 1
18
+ Sterol reductase, conserved site [IPR018083] 0.6615115261161453 0.9028227771680696 0.3666199605009674 1.0 0.8226929640589856 3 O76062,Q9UBM7 2
19
+ Cullin, conserved site [IPR016157] 0.5324491067205182 0.8974153287094557 0.3694973360434956 1.0 0.8226929640589856 6 Q13616,Q13619,Q93034,Q13617 4
20
+ Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866] 0.6361053342413483 0.8054828789603249 0.4205410823733113 1.0 0.8691182369048434 3 Q9P2R7 1
21
+ AMP-binding, conserved site [IPR020845] 0.4853451377696932 0.6846125503029278 0.4935884453124608 1.0 0.943227234535456 6 Q4G176,O14975 2
22
+ Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.4891530651793445 0.6688371748976573 0.5035993499493023 1.0 0.9558110111282676 8 P30837,P51649,P30038,P51648 4
23
+ Purine phosphorylase, family 2, conserved site [IPR018099] 0.7435822637106106 0.5977962661982895 0.5499758823519216 1.0 0.9817790586403912 2 Q13126 1
24
+ DnaJ domain, conserved site [IPR018253] 0.4791819247659175 0.5788507134213365 0.5626899087649697 1.0 0.9817790586403912 11 Q96KC8,Q9Y2G8 2
25
+ Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.5689780797474847 0.5608178318980611 0.5749217292319939 1.0 0.9817790586403912 3 P04439 1
26
+ Mrp, conserved site [IPR000808] 0.7173278879813304 0.5161557337456564 0.6057456443643419 1.0 0.9817790586403912 2 Q8TB37 1
27
+ Dynamin, GTPase region, conserved site [IPR019762] 0.7012835472578811 0.4685624524789232 0.6393824210149148 1.0 0.9908022213943328 2 O00429 1
28
+ Hexapeptide transferase, conserved site [IPR018357] 0.6662777129521658 0.3717355109375652 0.7100897827753903 1.0 0.9939003989424314 2 Q9Y5P6 1
29
+ Profilin conserved site [IPR027310] 0.661610268378068 0.3596224283519892 0.7191295088348739 1.0 0.9939003989424314 2 P07737 1
30
+ Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.6586931155192535 0.3521531956975973 0.7247233758407221 1.0 0.9939003989424314 2 P15880 1
31
+ S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082] 0.6356476079346483 0.2960006696794234 0.7672295699718488 1.0 0.9939003989424314 2 O43865 1
32
+ Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726] 0.6231038506417671 0.2676623188584343 0.7889592569462875 1.0 0.9939003989424314 2 Q07812 1
33
+ Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717] 0.6231038506417671 0.2676623188584343 0.7889592569462875 1.0 0.9939003989424314 2 Q07812 1
34
+ Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728] 0.6231038506417671 0.2676623188584343 0.7889592569462875 1.0 0.9939003989424314 2 Q07812 1
35
+ Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.4662970528158908 0.2510406957008056 0.801782645771717 1.0 0.9939003989424314 3 Q9Y2T2,Q96CW1 2
36
+ Heat shock protein Hsp90, conserved site [IPR019805] 0.4409104172745953 0.1924614955206239 0.8473807261691801 1.0 0.9939003989424314 3 P14625,P07900 2
37
+ Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.5169194865811136 0.096028702641312 0.9234977764875948 1.0 0.9939003989424314 2 P06737 1
38
+ Ribosomal RNA adenine methylase transferase, conserved site [IPR020596] 0.5084597432905612 0.0875534525891822 0.9302315994898858 1.0 0.9939003989424314 2 Q8WVM0 1
39
+ Thiosulphate sulfurtransferase, conserved site [IPR001307] 0.4664527421236881 0.0552837349305493 0.9559124199933082 1.0 0.9939003989424314 2 P25325 1
40
+ ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847] 0.4019836639439907 0.0305914438358375 0.9755953657877234 1.0 0.9939003989424314 2 P53396 1
41
+ GTP1/OBG, conserved site [IPR006074] 0.3771878646441047 0.0263594670075184 0.9789706235490564 1.0 0.9939003989424314 2 P55039 1
42
+ Serpin, conserved site [IPR023795] 0.3101838342573801 0.0256116030958955 0.9795671311745237 1.0 0.9939003989424314 3 P50454,P30740 2
43
+ XPG conserved site [IPR019974] 0.3710618436406059 0.0256061772421007 0.979571458960149 1.0 0.9939003989424314 2 Q9UQ84 1
44
+ Helix-hairpin-helix motif, class 2 [IPR008918] 0.3710618436406059 0.0256061772421007 0.979571458960149 1.0 0.9939003989424314 2 Q9UQ84 1
45
+ Ribosomal S11, conserved site [IPR018102] 0.3701866977829705 0.0255065414577988 0.9796509308572352 1.0 0.9939003989424314 2 P62263 1
interpro_conserved_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANKRD13A", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ARRB2", "ARSA", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "ATR", "BAG6", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT1", "BCAT2", "BCR", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CDC40", "CDH2", "CDKAL1", "CECR2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CREBBP", "CRYZ", "CSTB", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC2", "DSG2", "DST", "DTL", "DTYMK", "DUS2", "DUS3L", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "ITGA6", "ITGAV", "IVD", "KATNB1", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MOCS1", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NET1", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD2", "NSF", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NVL", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "POU2F1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL2", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RASAL2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "REL", "RELA", "RIDA", "RIOK1", "RIOK2", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SH3RF1", "SHPRH", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX12", "STX18", "STX3", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TM7SF2", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP32", "USP34", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR47", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ABCB7", "ABCB8", "ABCE1", "ACAD9", "ACADM", "ACLY", "ACSF3", "AHCYL1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "AP2M1", "AP3M1", "ATM", "ATR", "BAX", "CUL1", "CUL2", "CUL4A", "CUL5", "DHCR7", "DNAJC1", "DNAJC10", "DNAJC16", "DNM1L", "DRG2", "EARS2", "EXO1", "GMPPB", "HADH", "HADHA", "HLA-A", "HMGB1", "HMGB3", "HMOX2", "HSP90AA1", "HSP90B1", "IARS2", "IDH2", "IDH3A", "IDH3G", "IVD", "MIF", "MPST", "MRPL3", "MTAP", "MTOR", "NDUFS8", "NUBPL", "P4HB", "PDIA3", "PDIA4", "PDIA6", "PFN1", "PLOD3", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PYGL", "QARS", "RARS2", "RPS14", "RPS2", "SDHB", "SERPINB1", "SERPINH1", "SLC27A2", "SUCLA2", "TAP1", "TAP2", "TFB1M", "TM7SF2", "TMX1", "TMX4", "TXNDC12"]}
interpro_domain/advanced/idx2term.json ADDED
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+ {"0": "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "1": "ABC transporter-like, ATP-binding domain [IPR003439]", "2": "Immunoglobulin subtype [IPR003599]", "3": "Immunoglobulin-like domain [IPR007110]", "4": "DnaJ domain [IPR001623]", "5": "Thioredoxin domain [IPR013766]", "6": "Aldehyde dehydrogenase domain [IPR015590]", "7": "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "8": "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "9": "GTP binding domain [IPR006073]", "10": "ATPase, AAA-type, core [IPR003959]", "11": "Target SNARE coiled-coil homology domain [IPR000727]", "12": "EF-hand domain [IPR002048]"}
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+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:0169bf72282cc6166d78bd07c602a553149a363c4febcebd9704d311e608c381
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+ size 120295
interpro_domain/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 4 7 2.660902812397989 0.0077931447909271 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 1.0 2.2261381171916983e-05 0.0001778916397324 5.522373670119844e-06 0.0001590313802548
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+ Prolyl 4-hydroxylase, alpha subunit [IPR006620] 3 7 2.2876199023655297 0.0221596658510976 2.2184466019417477 6.415048543689321 0.633554567126164 0.4291196941966081 1.3185935116973673 1.1967053264777463 0.955977613408511 0.304094570424047 1.0 0.0607401038440192 0.1180585699575878 0.0002022933287296 0.0027834726260547
4
+ Oxoglutarate/iron-dependent dioxygenase [IPR005123] 3 7 2.2876199023655297 0.0221596658510976 2.174757281553398 6.449029126213592 0.6518715826129322 0.4280594236442204 1.299194556056103 1.212725418592039 0.9468550406660212 0.3043162658022956 1.0 0.083126337411673 0.1596960736798767 0.0007869115437374 0.0098193480789534
5
+ Aminoacyl-tRNA synthetase, class Ia [IPR002300] 0 6 2.2146750634507137 0.0267823756583045 2.621359223300971 5.759708737864078 -0.5400416753849419 0.5265176068734384 1.4787590235056545 0.4653299410110203 0.7072392648031367 0.2883625286397046 1.0 0.028497516818446 0.0563150378970086 0.1368589802283267 0.2586577321272367
6
+ Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155] 0 6 2.2146750634507137 0.0267823756583045 2.621359223300971 5.759708737864078 -0.5400416753849419 0.5265176068734384 1.4787590235056545 0.4653299410110203 0.7072392648031367 0.2883625286397046 1.0 0.028497516818446 0.0563150378970086 0.1368589802283267 0.2586577321272367
7
+ Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 6 9 2.0176069422784866 0.0436322132877797 3.058252427184466 8.66747572815534 -0.2891462610619146 0.4487119500832195 1.9337334618113893 1.0854780329838505 1.0649766578353217 0.2871756386364707 1.0 1.0 0.1094892401774078 0.00262770885776 3.957975029002194e-07
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+ Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038] 1 5 1.9761837942816252 0.0481339646529723 2.9611650485436893 5.067961165048544 -0.667320777745365 0.4263445669465814 1.3998774571686892 0.5789534569272068 0.9506639271252796 0.308773856990838 1.0 0.0378187125466048 0.002465796513642 0.0148625463558957 0.0544194668097373
9
+ FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 3 11 1.9736113178338752 0.0484259558284538 3.1262135922330097 10.111650485436892 0.9686720267359892 0.3700536707457866 1.7316562118191232 1.203619216216406 0.9607394322697528 0.3108814801432357 0.0177141571895901 0.0607401038440192 5.369271916582234e-06 0.0002022933287296 0.0027834726260547
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3430,
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+ "annotations_size": 2840,
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+ "title": "Average number of proteins per term",
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+ "value": 2.225704225352113
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+ }
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+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
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+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.933630435049054 2.6609028123979894 0.0077931447909271 0.999999999775966 0.7387015006880531 7 Q8WUJ1,Q9UMX5,O43169,O15173 4
3
+ Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.8440940626599138 2.2876199023655297 0.0221596658510976 1.0 0.7387015006880531 7 O60568,Q32P28,P13674 3
4
+ Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.8440940626599138 2.2876199023655297 0.0221596658510976 1.0 0.7387015006880531 7 O60568,Q32P28,P13674 3
5
+ Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.9498103297344612 2.036216000473855 0.0417286702576382 1.0 0.7387015006880531 3 Q32P28,P13674 2
6
+ Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.7904134754077595 2.0176069422784866 0.0436322132877797 1.0 0.7387015006880531 9 Q709F0,O15254,Q9H845,Q15067,P26440,P11310 6
7
+ Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038] 0.8264052703966154 1.9761837942816256 0.0481339646529723 1.0 0.7387015006880531 5 P55769 1
8
+ FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.789010387590173 1.9736113178338752 0.0484259558284538 1.0 0.7387015006880531 11 Q96AY3,Q9Y680,O95302 3
9
+ ABC transporter type 1, transmembrane domain [IPR011527] 0.7692489588614007 1.943662046888318 0.0519362182368694 1.0 0.7387015006880531 8 Q03519,P08183,O75027,Q03518 4
10
+ PIK-related kinase [IPR014009] 0.8175182481751709 1.939639782148767 0.0524234825770211 1.0 0.7387015006880531 5 Q13535,P78527,P42345,Q13315 4
11
+ PIK-related kinase, FAT [IPR003151] 0.8175182481751709 1.939639782148767 0.0524234825770211 1.0 0.7387015006880531 5 Q13535,P78527,P42345,Q13315 4
12
+ FATC domain [IPR003152] 0.8175182481751709 1.939639782148767 0.0524234825770211 1.0 0.7387015006880531 5 Q13535,P78527,P42345,Q13315 4
13
+ Tim10-like [IPR004217] 0.9235482929676015 1.9352171438210304 0.0529636548272813 1.0 0.7387015006880531 3 Q9Y5J9,Q9Y5L4 2
14
+ Aminotransferase, class I/classII [IPR004839] 0.7629051037458472 1.934774195836213 0.0530180109301769 1.0 0.7387015006880531 7 Q6YP21,O15269,O75600 3
15
+ MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.9220892909250032 1.9295808703087656 0.0536587909639705 1.0 0.7387015006880531 3 P04439,P10321 2
16
+ MHC class I, alpha chain, C-terminal [IPR010579] 0.9220892909250032 1.9295808703087656 0.0536587909639705 1.0 0.7387015006880531 3 P04439,P10321 2
17
+ Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075] 0.7595994851993104 1.9201252407275995 0.0548420817621504 1.0 0.7387015006880531 7 Q9H845,Q709F0,P26440,P11310 4
18
+ Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786] 0.7595994851993104 1.9201252407275995 0.0548420817621504 1.0 0.7387015006880531 7 Q9H845,Q709F0,P26440,P11310 4
19
+ Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058] 0.9108463635225488 1.88606216742259 0.0592865777148734 1.0 0.7387015006880531 3 P47897 1
20
+ FAD dependent oxidoreductase [IPR006076] 0.8388810059625681 1.8779940593318087 0.0603819777765566 1.0 0.7387015006880531 4 Q96CU9,Q9H9P8 2
21
+ Disulphide isomerase [IPR005788] 0.7932846715328365 1.839320989286854 0.0658679876350223 1.0 0.7387015006880531 5 P07237,P30101,P13667,Q15084 4
22
+ Glutamine amidotransferase [IPR017926] 0.8276751091022504 1.8328182256146557 0.0668296078341055 1.0 0.7387015006880531 4 Q9NRF8 1
23
+ Peptidase M3A/M3B catalytic domain [IPR001567] 0.8881781540263984 1.797872356627628 0.0721972376700603 1.0 0.7387015006880531 3 Q99797 1
24
+ Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.7282819055010055 1.761169713156314 0.0782096825782661 1.0 0.7387015006880531 8 Q13535,P78527,P42345,Q13315 4
25
+ Fibronectin type III [IPR003961] 0.722542991675909 1.7544796845892296 0.0793483479534509 1.0 0.7387015006880531 7 Q8NAT1 1
26
+ Major facilitator superfamily domain [IPR020846] 0.7947054374476834 1.6988990224123643 0.0893382112517819 1.0 0.7387015006880531 4 Q14728 1
27
+ Homeobox domain [IPR001356] 0.7797843852552289 1.6378341983134448 0.101456285520121 1.0 0.7387015006880531 4 Q96G23 1
28
+ CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.8390545633923668 1.6049417474833594 0.1085066249761577 1.0 0.7463688753665311 3 Q9NUQ9 1
29
+ 3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.8335101654749797 1.5830333856209269 0.1134138551516228 1.0 0.7463688753665311 3 Q16836 1
30
+ 3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.8335101654749797 1.5830333856209269 0.1134138551516228 1.0 0.7463688753665311 3 Q16836 1
31
+ Peptidase M16, C-terminal [IPR007863] 0.6816099001510736 1.568689004226966 0.1167204219715689 1.0 0.7463688753665311 7 Q5JRX3,Q10713,O75439,P22695 4
32
+ Peptidase M16, N-terminal [IPR011765] 0.6816099001510736 1.568689004226966 0.1167204219715689 1.0 0.7463688753665311 7 Q5JRX3,Q10713,O75439,P22695 4
33
+ Phospholipid/glycerol acyltransferase [IPR002123] 0.6810248939011172 1.5660145682879476 0.1173452066298965 1.0 0.7463688753665311 7 Q8NF37,Q99943,Q643R3,O15228 4
34
+ Patatin-like phospholipase domain [IPR002641] 0.8246279544791348 1.5478895085275226 0.1216489010150763 1.0 0.7463688753665311 3 Q9NP80,P41247 2
35
+ Histidine kinase domain [IPR005467] 0.8176247446746171 1.5201433637744268 0.1284749480502922 1.0 0.7464932843732234 3 Q15120,O14874 2
36
+ Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955] 0.8176247446746171 1.5201433637744268 0.1284749480502922 1.0 0.7464932843732234 3 Q15120,O14874 2
37
+ Band 7 domain [IPR001107] 0.6671132216791938 1.5022741460126037 0.133026322802207 1.0 0.757103720958453 7 Q99623,Q9UJZ1 2
38
+ Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.7389252283882045 1.469385598662245 0.1417282312165761 1.0 0.7716025058048761 4 Q86TI2 1
39
+ Cold-shock (CSD) domain [IPR019844] 0.7959646040550891 1.4341588347040568 0.151526941382323 1.0 0.7885819293639469 3 P67809 1
40
+ ABC transporter-like, ATP-binding domain [IPR003439] 0.6705270606551084 1.4243035841079643 0.154358610439548 1.0 0.7885819293639469 12 Q03519,P08183,P61221,Q9NUT2,Q03518,O75027 6
41
+ CTP synthase, N-terminal [IPR017456] 0.9743290548424712 1.4231660727742628 0.1546880182031342 1.0 0.7885819293639469 2 Q9NRF8 1
42
+ CTP synthase GATase domain [IPR033828] 0.9743290548424712 1.4231660727742628 0.1546880182031342 1.0 0.7885819293639469 2 Q9NRF8 1
43
+ 4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.7256275539988079 1.4142476975507023 0.1572891877529798 1.0 0.7885819293639469 4 P61221,O00217,P21912 3
44
+ Immunoglobulin C1-set [IPR003597] 0.6827341525950755 1.3710034171117602 0.1703738908162111 1.0 0.7885819293639469 5 P04439,P01889,P10321 3
45
+ P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.6787904607243335 1.354053571032566 0.1757192872144279 1.0 0.7885819293639469 5 Q9HD20 1
46
+ DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133] 0.7725885325086439 1.3411754882407554 0.1798634827299796 1.0 0.7885819293639469 3 Q07864 1
47
+ DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134] 0.7725885325086439 1.3411754882407554 0.1798634827299796 1.0 0.7885819293639469 3 Q07864 1
48
+ Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.9495332555425862 1.3303232470455768 0.1834117909404313 1.0 0.7885819293639469 2 P13674 1
49
+ TRAM/LAG1/CLN8 homology domain [IPR006634] 0.7697917336593494 1.3300447681524306 0.1835035215543046 1.0 0.7885819293639469 3 Q96G23 1
50
+ ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.9477829638273016 1.3237783187924848 0.1855766787774033 1.0 0.7885819293639469 2 Q5T9A4 1
51
+ TGS [IPR004095] 0.6180899555090426 1.2759261928090873 0.2019816109683534 1.0 0.8001119397459 7 Q9BW92,Q9NYK5,P55039 3
52
+ GNAT domain [IPR000182] 0.6591788026953798 1.2696353725810656 0.2042145433106119 1.0 0.8001119397459 5 Q86UY6 1
53
+ Domain of unknown function DUF3517 [IPR021905] 0.7478844470382093 1.2428765334917888 0.213913334307463 1.0 0.8129389103840952 3 Q9UPU5,Q70CQ2 2
54
+ Isopropylmalate dehydrogenase-like domain [IPR024084] 0.6439494196168543 1.2039915406565087 0.2285928481768739 1.0 0.8364124133906076 5 P48735,P50213,P51553 3
55
+ Tyrosine-specific protein phosphatase, PTPase domain [IPR000242] 0.6711124702096518 1.1873933785351605 0.235072490580678 1.0 0.8418737367580398 4 P10586 1
56
+ MHC class I-like antigen recognition-like [IPR011161] 0.6680697162097788 1.1747257690644923 0.2401044463498085 1.0 0.8450801839419022 4 P04439,P10321 2
57
+ Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861] 0.726750740855783 1.1589321981386271 0.2464838231960999 1.0 0.8450801839419022 3 O60568 1
58
+ Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.7220942933596948 1.1404732628762604 0.2540891856238529 1.0 0.8450801839419022 3 Q1KMD3 1
59
+ Saccharopine dehydrogenase-like, C-terminal [IPR032095] 0.8964410735122414 1.1327943673813163 0.2573006173901515 1.0 0.8450801839419022 2 Q8NBX0 1
60
+ Saccharopine dehydrogenase, NADP binding domain [IPR005097] 0.8964410735122414 1.1327943673813163 0.2573006173901515 1.0 0.8450801839419022 2 Q8NBX0 1
61
+ Anticodon-binding [IPR004154] 0.5798691882164941 1.09857791828892 0.2719522137524612 1.0 0.8632384036545204 7 Q9BW92 1
62
+ Acyl-CoA oxidase, C-terminal [IPR002655] 0.887106184364052 1.0983729250108745 0.2720416800249281 1.0 0.8632384036545204 2 Q15067 1
63
+ Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886] 0.8853558926487748 1.0919328996487565 0.2748625956429604 1.0 0.867344190695564 2 Q9UDR5 1
64
+ Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698] 0.8853558926487748 1.0919328996487565 0.2748625956429604 1.0 0.867344190695564 2 Q9UDR5 1
65
+ Ribosomal protein L18e/L15P [IPR021131] 0.7058154409933135 1.0760952879616894 0.2818846428260102 1.0 0.881665622935979 3 Q9P015 1
66
+ Protein-tyrosine phosphatase, catalytic [IPR003595] 0.5705615091641121 1.055443009933876 0.2912227609999671 1.0 0.8817487363734434 7 P10586,Q9H3S7,Q9ULE6 3
67
+ Immunoglobulin subtype [IPR003599] 0.5703873003278895 1.0546362679868555 0.2915917099100573 1.0 0.8817487363734434 7 P78310,Q8WX93,Q92692,P35613,P10586 5
68
+ Threonyl/alanyl tRNA synthetase, SAD [IPR012947] 0.5618683900526952 1.0332664241115428 0.3014792354240398 1.0 0.8835923927804678 6 Q9BW92 1
69
+ Tim44-like domain [IPR007379] 0.867269544924145 1.0256803111055923 0.3050422979076757 1.0 0.8856860094334419 2 Q9BRJ2 1
70
+ Legume-like lectin [IPR005052] 0.8649358226371058 1.0171744575645316 0.3090704446532271 1.0 0.8929400435556103 2 P49257 1
71
+ N-acetylgalactosaminyltransferase [IPR045885] 0.6833923213032993 0.9879595685331052 0.3231724498418757 1.0 0.903565680512786 3 Q8N4A0 1
72
+ Immunoglobulin subtype 2 [IPR003598] 0.5510297561203354 0.9830616189906488 0.3255771127004925 1.0 0.903565680512786 6 P78310,Q8WX93,P35613,P10586 4
73
+ Vicinal oxygen chelate (VOC) domain [IPR037523] 0.8538506417736179 0.976923070116388 0.3286072394858348 1.0 0.9080370715766514 2 Q9HC38 1
74
+ Zinc finger, CHHC-type [IPR012996] 0.6801867522614593 0.9754259251635304 0.3293490289980507 1.0 0.9081080022858874 3 P31943,P52597 2
75
+ S100/CaBP-9k-type, calcium binding, subdomain [IPR013787] 0.678011363764466 0.9669311867286736 0.3335784349526745 1.0 0.9092591889579832 3 P31949 1
76
+ Immunoglobulin-like domain [IPR007110] 0.56900690911189 0.9596452885479632 0.3372337675881041 1.0 0.9092591889579832 12 P04439,P01889,Q92692,P35613,O15533,P10321,P10586 7
77
+ CARG-binding factor, N-terminal [IPR012956] 0.8483080513418901 0.9568981314691544 0.3386186744283044 1.0 0.9092591889579832 2 Q14103 1
78
+ Metaxin, glutathione S-transferase domain [IPR033468] 0.8456826137689653 0.9474377720465408 0.3434157514146214 1.0 0.9092591889579832 2 Q13505 1
79
+ Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.8456826137689653 0.9474377720465408 0.3434157514146214 1.0 0.9092591889579832 2 Q13505 1
80
+ Ras-associating (RA) domain [IPR000159] 0.6110032968850079 0.938430513794714 0.3480232108124736 1.0 0.9158817393512452 4 Q96L92,Q9Y4G8 2
81
+ Pentacotripeptide-repeat region of PRORP [IPR033443] 0.8404317386231053 0.9285678919357334 0.3531130680739169 1.0 0.9208825650412528 2 P42704 1
82
+ HECT domain [IPR000569] 0.5579615942789297 0.9095027093910076 0.3630848282964833 1.0 0.9251373198260554 12 Q96PU5 1
83
+ Cullin protein, neddylation domain [IPR019559] 0.5324491067205182 0.8974153287094557 0.3694973360434956 1.0 0.9260365224823516 6 Q13616,Q13619,Q93034,Q13617 4
84
+ Cullin homology domain [IPR016158] 0.5324491067205182 0.8974153287094557 0.3694973360434956 1.0 0.9260365224823516 6 Q13616,Q13619,Q93034,Q13617 4
85
+ Cullin, N-terminal [IPR001373] 0.5324491067205182 0.8974153287094557 0.3694973360434956 1.0 0.9260365224823516 6 Q13616,Q13619,Q93034,Q13617 4
86
+ Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630] 0.6601121479631085 0.897414501671515 0.3694977771923928 1.0 0.9260365224823516 3 P13995 1
87
+ Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631] 0.6601121479631085 0.897414501671515 0.3694977771923928 1.0 0.9260365224823516 3 P13995 1
88
+ ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194] 0.5988756816796552 0.8888108898902624 0.3741047222923741 1.0 0.9291154010664218 4 P06576 1
89
+ ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100] 0.5988756816796552 0.8888108898902624 0.3741047222923741 1.0 0.9291154010664218 4 P06576 1
90
+ Elp3/MiaB/NifB [IPR006638] 0.6524657134519931 0.8679523247103571 0.3854204325196959 1.0 0.9395182671752214 3 Q5VV42,Q9H9T3 2
91
+ Radical SAM [IPR007197] 0.6524657134519931 0.8679523247103571 0.3854204325196959 1.0 0.9395182671752214 3 Q5VV42,Q9H9T3 2
92
+ RGS domain [IPR016137] 0.6512315253106362 0.8632117674736047 0.3880210449374441 1.0 0.9419033091498764 3 O43572 1
93
+ EGF-like domain [IPR000742] 0.5232619964614023 0.8380262423957376 0.4020159651637984 1.0 0.945592397930447 7 O94813 1
94
+ GOLD domain [IPR009038] 0.522981428853532 0.8367509707457929 0.402732561922416 1.0 0.945592397930447 7 P49755,Q9Y3B3,Q9BVK6 3
95
+ Histidine kinase/HSP90-like ATPase [IPR003594] 0.5336840534865172 0.8339109274678689 0.4043311790164496 1.0 0.947442696705212 10 Q15118,Q15120,Q12931,O14874 4
96
+ Gamma-adaptin ear (GAE) domain [IPR008153] 0.6432354037735506 0.8326058514263079 0.4050670578238591 1.0 0.9478435697752798 3 Q9UJY4 1
97
+ Immunoglobulin V-set domain [IPR013106] 0.8130105017502913 0.8312688992712748 0.4058217398607258 1.0 0.948010442614148 2 Q92692 1
98
+ Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252] 0.8089264877479443 0.816978651844388 0.4139406280744329 1.0 0.9564828458170288 2 Q643R3 1
99
+ Vps4 oligomerisation, C-terminal [IPR015415] 0.6373046023327491 0.8100332089468563 0.4179210895630529 1.0 0.9566369877860824 3 P55072 1
100
+ Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906] 0.8068844807467873 0.8098551765388524 0.4180234161417353 1.0 0.9566369877860824 2 Q15418 1
101
+ Diacylglycerol kinase, catalytic domain [IPR001206] 0.8028004667444595 0.7956528611153357 0.4262338327057406 1.0 0.959302014926382 2 P52429 1
102
+ Cold-shock protein, DNA-binding [IPR002059] 0.5682603208285412 0.7652362988727641 0.4441308483946826 1.0 0.9643901060147728 4 P67809 1
103
+ Cold shock domain [IPR011129] 0.5682603208285412 0.7652362988727641 0.4441308483946826 1.0 0.9643901060147728 4 P67809 1
104
+ FAST kinase leucine-rich [IPR010622] 0.7937572928821508 0.7644263221843249 0.4446132276477619 1.0 0.9643901060147728 2 Q969Z0 1
105
+ FAST kinase-like protein, subdomain 2 [IPR013579] 0.7937572928821508 0.7644263221843249 0.4446132276477619 1.0 0.9643901060147728 2 Q969Z0 1
106
+ RAP domain [IPR013584] 0.7937572928821508 0.7644263221843249 0.4446132276477619 1.0 0.9643901060147728 2 Q969Z0 1
107
+ Aminopeptidase N-like , N-terminal domain [IPR045357] 0.5030159661913888 0.763484518631697 0.4451744916571272 1.0 0.9643901060147728 6 Q9NZ08 1
108
+ Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.5030159661913888 0.763484518631697 0.4451744916571272 1.0 0.9643901060147728 6 Q9NZ08 1
109
+ Phospholipase D/Transphosphatidylase [IPR001736] 0.7855892648774745 0.7365004425220986 0.4614261983636867 1.0 0.9743125675486024 2 Q8N2A8 1
110
+ v-SNARE, coiled-coil homology domain [IPR042855] 0.6148234607528544 0.7256145015921287 0.4680751285576447 1.0 0.9775565233905352 3 P51809,O15498 2
111
+ Longin domain [IPR010908] 0.6148234607528544 0.7256145015921287 0.4680751285576447 1.0 0.9775565233905352 3 P51809,O15498 2
112
+ Exportin-2, central domain [IPR013713] 0.6020016146530696 0.6784118956354922 0.4975105687970527 1.0 0.9900486408552168 3 O95373 1
113
+ Glutathione S-transferase, N-terminal [IPR004045] 0.492766135298012 0.6685390266632907 0.5037895787478996 1.0 0.9900486408552168 9 O15217,P78417 2
114
+ Glutathione S-transferase, C-terminal [IPR004046] 0.4968118422287243 0.6542416717755088 0.5129561179081179 1.0 0.9928540056920678 11 O15217 1
115
+ Sec63 domain [IPR004179] 0.5841217307376914 0.6139609881018656 0.5392411069552119 1.0 0.9928540056920678 3 Q9UGP8 1
116
+ Clp ATPase, C-terminal [IPR019489] 0.7470828471411901 0.6090015592821698 0.5425234053544283 1.0 0.9928540056920678 2 O76031 1
117
+ Nucleoside phosphorylase domain [IPR000845] 0.7435822637106106 0.5977962661982895 0.5499758823519216 1.0 0.9928540056920678 2 Q13126 1
118
+ Class I myosin, motor domain [IPR036072] 0.5252496157511283 0.5977691045553037 0.5499940082612909 1.0 0.9928540056920678 4 O94832,O43795 2
119
+ Class I myosin tail homology domain [IPR010926] 0.5252496157511283 0.5977691045553037 0.5499940082612909 1.0 0.9928540056920678 4 O94832,O43795 2
120
+ Hexokinase, C-terminal [IPR022673] 0.7424154025670804 0.5940769700475008 0.5524606334501816 1.0 0.9928540056920678 2 P52789 1
121
+ Hexokinase, N-terminal [IPR022672] 0.7424154025670804 0.5940769700475008 0.5524606334501816 1.0 0.9928540056920678 2 P52789 1
122
+ Peptidase M41 [IPR000642] 0.7377479579929789 0.5792804952380668 0.5623999241609039 1.0 0.9928540056920678 2 Q9Y4W6 1
123
+ Cyclic nucleotide-binding domain [IPR000595] 0.4939885241707074 0.5745340224464207 0.5656064844463495 1.0 0.9928540056920678 5 Q9Y4G8 1
124
+ DnaJ domain [IPR001623] 0.5058171102590417 0.5703350237696236 0.5684504903802234 1.0 0.9928540056920678 19 Q96KC8,Q13217,Q9Y2G8,Q9UBS4,Q9UGP8,Q8IXB1 6
125
+ Glycosyltransferase 2-like [IPR001173] 0.5171707402455751 0.5674124398119751 0.5704340001515149 1.0 0.9928540056920678 4 Q8N4A0 1
126
+ Ricin B, lectin domain [IPR000772] 0.5171707402455751 0.5674124398119751 0.5704340001515149 1.0 0.9928540056920678 4 Q8N4A0 1
127
+ ERAP1-like C-terminal domain [IPR024571] 0.5147362282028152 0.5583466068765938 0.5766077249675507 1.0 0.9928540056920678 4 Q9NZ08 1
128
+ Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120] 0.7287047841306934 0.5509922843736551 0.5816389637175208 1.0 0.9928540056920678 2 Q96K12 1
129
+ Fatty acyl-CoA reductase, C-terminal [IPR033640] 0.7287047841306934 0.5509922843736551 0.5816389637175208 1.0 0.9928540056920678 2 Q96K12 1
130
+ Amino acid permease/ SLC12A domain [IPR004841] 0.7272462077012831 0.5464781949207955 0.5847372723721334 1.0 0.9928540056920678 2 P55011 1
131
+ SLC12A transporter, C-terminal [IPR018491] 0.7272462077012831 0.5464781949207955 0.5847372723721334 1.0 0.9928540056920678 2 P55011 1
132
+ Thioredoxin domain [IPR013766] 0.5172231215015031 0.5447462957553552 0.5859280193090872 1.0 0.9928540056920678 24 P30044,Q9Y2G8,Q9H3N1,Q9H1E5,P13667,P07237,Q9Y320,O95881,Q13162,Q15084,Q8IXB1,P30101,Q9BS26 13
133
+ NIPSNAP [IPR012577] 0.7234539089848304 0.5348066022122867 0.5927835972048308 1.0 0.9928540056920678 2 Q9BPW8 1
134
+ Heat shock protein Hsp90, N-terminal [IPR020575] 0.482828526295147 0.5311541591540837 0.5953119562182834 1.0 0.9928540056920678 5 Q58FF6,Q12931 2
135
+ Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598] 0.5601985296066921 0.5306936345707765 0.5956310977849819 1.0 0.9928540056920678 3 Q9H5Q4 1
136
+ Serine hydroxymethyltransferase-like domain [IPR039429] 0.7138273045507414 0.5056139626416377 0.6131276777480037 1.0 0.9928540056920678 2 P34897 1
137
+ Dynein heavy chain, tail [IPR013594] 0.7129521586931189 0.502991967288426 0.6149699197452172 1.0 0.9928540056920678 2 Q8NCM8 1
138
+ Dynein heavy chain AAA lid domain [IPR041658] 0.7129521586931189 0.502991967288426 0.6149699197452172 1.0 0.9928540056920678 2 Q8NCM8 1
139
+ Dynein heavy chain region D6 P-loop domain [IPR004273] 0.7129521586931189 0.502991967288426 0.6149699197452172 1.0 0.9928540056920678 2 Q8NCM8 1
140
+ Dynein heavy chain, AAA module D4 [IPR024317] 0.7129521586931189 0.502991967288426 0.6149699197452172 1.0 0.9928540056920678 2 Q8NCM8 1
141
+ Dynein heavy chain, coiled coil stalk [IPR024743] 0.7129521586931189 0.502991967288426 0.6149699197452172 1.0 0.9928540056920678 2 Q8NCM8 1
142
+ Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699] 0.7129521586931189 0.502991967288426 0.6149699197452172 1.0 0.9928540056920678 2 Q8NCM8 1
143
+ Dynein heavy chain, ATP-binding dynein motor region [IPR035706] 0.7129521586931189 0.502991967288426 0.6149699197452172 1.0 0.9928540056920678 2 Q8NCM8 1
144
+ Dynein heavy chain, C-terminal domain [IPR041228] 0.7129521586931189 0.502991967288426 0.6149699197452172 1.0 0.9928540056920678 2 Q8NCM8 1
145
+ Dynein heavy chain, linker [IPR013602] 0.7129521586931189 0.502991967288426 0.6149699197452172 1.0 0.9928540056920678 2 Q8NCM8 1
146
+ LSM domain, eukaryotic/archaea-type [IPR001163] 0.4462657395145543 0.501617266207342 0.615936771534735 1.0 0.9928540056920678 7 P62316,Q9Y333 2
147
+ Proteasome alpha-subunit, N-terminal domain [IPR000426] 0.4456353478079174 0.4990226949494132 0.6177633959469708 1.0 0.9928540056920678 7 P60900,P25787 2
148
+ PAP/25A-associated [IPR002058] 0.7114935822637023 0.4986340671453801 0.6180372008580353 1.0 0.9928540056920678 2 Q9NVV4 1
149
+ TUTase nucleotidyltransferase domain [IPR045100] 0.7114935822637023 0.4986340671453801 0.6180372008580353 1.0 0.9928540056920678 2 Q9NVV4 1
150
+ Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152] 0.4453714013978314 0.4979373744888888 0.6185281834455869 1.0 0.9928540056920678 7 Q9UJY4 1
151
+ Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004] 0.5460444938178578 0.483305008056034 0.6288791846631883 1.0 0.9928540056920678 3 P11940 1
152
+ Tyrosine-specific protein phosphatases domain [IPR000387] 0.4449859105248656 0.4817322934004984 0.6299961323108869 1.0 0.9928540056920678 8 Q9H3S7,P10586 2
153
+ Condensin complex subunit 1, C-terminal [IPR032682] 0.7053675612601911 0.4804986953183904 0.6308728306702942 1.0 0.9928540056920678 2 P42695 1
154
+ Aldehyde dehydrogenase domain [IPR015590] 0.4538058140927405 0.4742120409613045 0.6353487077706041 1.0 0.9928540056920678 11 P30837,P30038,P51648,P54886,P51649 5
155
+ Dynamin stalk domain [IPR000375] 0.7012835472578811 0.4685624524789232 0.6393824210149148 1.0 0.9928540056920678 2 O00429 1
156
+ GTPase effector domain [IPR020850] 0.7012835472578811 0.4685624524789232 0.6393824210149148 1.0 0.9928540056920678 2 O00429 1
157
+ Dynamin GTPase effector [IPR003130] 0.7012835472578811 0.4685624524789232 0.6393824210149148 1.0 0.9928540056920678 2 O00429 1
158
+ Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939] 0.6957409568261399 0.4525662117112318 0.6508611335706127 1.0 0.9928540056920678 2 P32322 1
159
+ Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036] 0.6957409568261399 0.4525662117112318 0.6508611335706127 1.0 0.9928540056920678 2 P32322 1
160
+ Dynamin, GTPase domain [IPR001401] 0.5339825707304884 0.4441750728981026 0.6569160128094436 1.0 0.9928540056920678 3 O00429 1
161
+ Peptidase C14, p20 domain [IPR001309] 0.6887397899650001 0.4327046559098759 0.6652293469351469 1.0 0.9928540056920678 2 P42574 1
162
+ Peptidase C14A, caspase catalytic domain [IPR015917] 0.6887397899650001 0.4327046559098759 0.6652293469351469 1.0 0.9928540056920678 2 P42574 1
163
+ Peptidase C14, caspase non-catalytic subunit p10 [IPR002138] 0.6887397899650001 0.4327046559098759 0.6652293469351469 1.0 0.9928540056920678 2 P42574 1
164
+ CRA domain [IPR013144] 0.6875729288214744 0.4294326614993473 0.6676083889701905 1.0 0.9928540056920678 2 Q96S59 1
165
+ CTLH/CRA C-terminal to LisH motif domain [IPR024964] 0.6875729288214744 0.4294326614993473 0.6676083889701905 1.0 0.9928540056920678 2 Q96S59 1
166
+ WWE domain [IPR004170] 0.5290199306634721 0.4284371600818918 0.6683328750747164 1.0 0.9928540056920678 3 Q7Z6Z7 1
167
+ AMP-dependent synthetase/ligase [IPR000873] 0.4249502108297493 0.4159614489201682 0.6774382131099501 1.0 0.9928540056920678 7 Q4G176,O14975 2
168
+ Ribosomal Proteins L2, RNA binding domain [IPR022666] 0.6770711785297585 0.400492425144304 0.6887938615573277 1.0 0.9928540056920678 2 P62917 1
169
+ Ribosomal protein L2, C-terminal [IPR022669] 0.6770711785297585 0.400492425144304 0.6887938615573277 1.0 0.9928540056920678 2 P62917 1
170
+ SGNH hydrolase-type esterase domain [IPR013830] 0.5189395925637721 0.3971594819460878 0.6912498589396479 1.0 0.9928540056920678 3 P68402 1
171
+ Mu homology domain [IPR028565] 0.4664331582019908 0.3879477888109556 0.6980546718870995 1.0 0.9928540056920678 4 Q9Y2T2,P48444,Q96CW1 3
172
+ tRNA-guanine(15) transglycosylase-like [IPR002616] 0.6656942823804002 0.3702105566813608 0.7112256114355122 1.0 0.9928540056920678 2 Q9H974 1
173
+ AMP-binding enzyme, C-terminal domain [IPR025110] 0.4580522227994349 0.3605544489966527 0.7184325462428172 1.0 0.9928540056920678 4 Q4G176 1
174
+ Ribosomal protein S5, C-terminal [IPR005324] 0.6586931155192535 0.3521531956975973 0.7247233758407221 1.0 0.9928540056920678 2 P15880 1
175
+ Ribosomal protein S5, N-terminal [IPR013810] 0.6586931155192535 0.3521531956975973 0.7247233758407221 1.0 0.9928540056920678 2 P15880 1
176
+ ATP-citrate lyase/succinyl-CoA ligase [IPR005811] 0.4513214236811408 0.3390991020344187 0.734535074878248 1.0 0.9928540056920678 4 Q9P2R7 1
177
+ NAD-dependent epimerase/dehydratase [IPR001509] 0.6511085180863458 0.3331059010495837 0.7390543451276295 1.0 0.9928540056920678 2 Q13630 1
178
+ PTB/PI domain [IPR006020] 0.4493520747873101 0.3329168781471098 0.7391970285773266 1.0 0.9928540056920678 4 O00213 1
179
+ MRH domain [IPR044865] 0.4472939137653106 0.3265030816240384 0.7440437581429484 1.0 0.9928540056920678 4 Q13438 1
180
+ Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.6481913652275448 0.3259258549600789 0.7444804534510625 1.0 0.9928540056920678 2 O60506 1
181
+ Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263] 0.6446907817969726 0.3174185941078477 0.7509260001016687 1.0 0.9928540056920678 2 O00443 1
182
+ Sec23/Sec24, trunk domain [IPR006896] 0.4200626980104576 0.3071935917083983 0.7586960229482509 1.0 0.9928540056920678 5 O95487 1
183
+ Zinc finger, Sec23/Sec24-type [IPR006895] 0.4200626980104576 0.3071935917083983 0.7586960229482509 1.0 0.9928540056920678 5 O95487 1
184
+ Sec23/Sec24, helical domain [IPR006900] 0.4200626980104576 0.3071935917083983 0.7586960229482509 1.0 0.9928540056920678 5 O95487 1
185
+ Sec23/Sec24 beta-sandwich [IPR012990] 0.4200626980104576 0.3071935917083983 0.7586960229482509 1.0 0.9928540056920678 5 O95487 1
186
+ Immunoglobulin I-set [IPR013098] 0.4409828722760912 0.3071437496217499 0.7587339586281621 1.0 0.9928540056920678 4 Q8WX93,P10586 2
187
+ S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878] 0.6356476079346483 0.2960006696794234 0.7672295699718488 1.0 0.9928540056920678 2 O43865 1
188
+ SMCs flexible hinge [IPR010935] 0.4122627737226326 0.28235480559186 0.7776714655415704 1.0 0.9928540056920678 5 Q9NTJ3,Q14683,A6NHR9,O95347 4
189
+ Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040] 0.6289381563593983 0.2806417771317298 0.7789851696674734 1.0 0.9928540056920678 2 Q9Y678 1
190
+ Coatomer subunit gamma, C-terminal [IPR032154] 0.6289381563593983 0.2806417771317298 0.7789851696674734 1.0 0.9928540056920678 2 Q9Y678 1
191
+ Poly(ADP-ribose) polymerase, catalytic domain [IPR012317] 0.4770120718185412 0.2782185405927707 0.780844603172919 1.0 0.9928540056920678 3 Q7Z2W4 1
192
+ Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543] 0.6242707117852926 0.2702299331990699 0.7869833656637615 1.0 0.9928540056920678 2 Q13555 1
193
+ Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.3814112750424873 0.2689787599546923 0.7879460276222987 1.0 0.9928540056920678 6 P50570,O00429,Q9H223 3
194
+ Dynamin, N-terminal [IPR045063] 0.3814112750424873 0.2689787599546923 0.7879460276222987 1.0 0.9928540056920678 6 P50570,O00429,Q9H223 3
195
+ SAC3/GANP/THP3, conserved domain [IPR005062] 0.621936989498258 0.265108927654367 0.7909255500647561 1.0 0.9928540056920678 2 O60318 1
196
+ JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.3825248392752816 0.2497187226749777 0.8028048782265937 1.0 0.9928540056920678 8 Q92905,O00487,O15372,P51665,O00303,O95630,Q6P2Q9 7
197
+ PIN domain [IPR002716] 0.4616282462795618 0.2396437151996096 0.8106064722244632 1.0 0.9928540056920678 3 Q9ULX3,Q9Y2L1 2
198
+ Guanine nucleotide exchange factor, N-terminal [IPR032691] 0.6091015169194953 0.2379714828752011 0.8119032122700929 1.0 0.9928540056920678 2 Q92538 1
199
+ Potassium channel tetramerisation-type BTB domain [IPR003131] 0.6061843640606854 0.2320496568112746 0.8164994456655423 1.0 0.9928540056920678 2 Q9H3F6 1
200
+ CRIB domain [IPR000095] 0.4569594397432246 0.2285233603836378 0.8192393975730323 1.0 0.9928540056920678 3 Q9Y5S2,Q13177 2
201
+ Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610] 0.5962660443407324 0.2126068486901272 0.8316336290919579 1.0 0.9928540056920678 2 Q9NZ45 1
202
+ Iron-binding zinc finger, CDGSH type [IPR018967] 0.5962660443407324 0.2126068486901272 0.8316336290919579 1.0 0.9928540056920678 2 Q9NZ45 1
203
+ Transketolase-like, pyrimidine-binding domain [IPR005475] 0.406815498400533 0.211078055065985 0.8328263639681697 1.0 0.9928540056920678 4 P21953 1
204
+ SCP2 sterol-binding domain [IPR003033] 0.4490808287131745 0.2103964218400764 0.8333582851150887 1.0 0.9928540056920678 3 P22307,P51659 2
205
+ Kinesin-like [IPR022164] 0.4473300262620485 0.2064786188035092 0.8364170646221201 1.0 0.9928540056920678 3 O60333,Q12756 2
206
+ Acyltransferase, C-terminal domain [IPR032098] 0.4438284213598079 0.1987648172436421 0.8424467185920577 1.0 0.9928540056920678 3 Q9NUQ2,Q6UWP7 2
207
+ Nucleotidyl transferase domain [IPR005835] 0.4420776189086844 0.1949691519459146 0.8454170973422943 1.0 0.9928540056920678 3 Q96IJ6,Q9Y5P6 2
208
+ Translational (tr)-type GTP-binding domain [IPR000795] 0.3751807275205222 0.1844597748666508 0.8536527806482639 1.0 0.9928540056920678 12 Q8N442,Q9Y450,P46199 3
209
+ Nuclear transport factor 2, eukaryote [IPR018222] 0.3855808523059022 0.1595737538907696 0.8732168553702044 1.0 0.9928540056920678 4 Q9UN86,P61970,Q9UBU9 3
210
+ Nuclear transport factor 2 domain [IPR002075] 0.3855808523059022 0.1595737538907696 0.8732168553702044 1.0 0.9928540056920678 4 Q9UN86,P61970,Q9UBU9 3
211
+ Alcohol dehydrogenase-like, C-terminal [IPR013149] 0.352253303479481 0.1574734895237346 0.8748716995028583 1.0 0.9928540056920678 8 Q8N8N7,Q8N4Q0 2
212
+ Gelsolin-like domain [IPR007123] 0.3454521184413116 0.1573267966683494 0.8749873025396486 1.0 0.9928540056920678 6 O95487 1
213
+ Ribosomal protein L11, C-terminal [IPR020783] 0.547549591598612 0.1328920448388418 0.8942787584003484 1.0 0.9928540056920678 2 P30050 1
214
+ Ribosomal protein L11, N-terminal [IPR020784] 0.547549591598612 0.1328920448388418 0.8942787584003484 1.0 0.9928540056920678 2 P30050 1
215
+ Protein kinase, C-terminal [IPR017892] 0.3424301137885508 0.1310116515150225 0.8957660902759297 1.0 0.9928540056920678 8 Q15418 1
216
+ MIT domain [IPR007330] 0.3657326328079451 0.1176114440286442 0.9063755368612358 1.0 0.9928540056920678 4 Q8N0X7,Q9UN37,O75351 3
217
+ Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553] 0.34269005847953 0.1146236667989343 0.9087434199549398 1.0 0.9928540056920678 10 O00203,O94973,Q9Y678,O43747,P63010,O95782,P53618,Q9UBF2,O14617 9
218
+ Cyclin, N-terminal [IPR006671] 0.5312135355892758 0.1120000062450785 0.9108234016197716 1.0 0.9928540056920678 2 P14635 1
219
+ Cyclin, C-terminal domain [IPR004367] 0.5312135355892758 0.1120000062450785 0.9108234016197716 1.0 0.9928540056920678 2 P14635 1
220
+ GTP binding domain [IPR006073] 0.3547050074392762 0.1112333894133675 0.9114312749905789 1.0 0.9928540056920678 14 O43824,Q969Y2,O75616,Q8NC60,P36915 5
221
+ Valyl tRNA synthetase, anticodon-binding domain [IPR033705] 0.5285880980163467 0.1089075713712906 0.9132758012832324 1.0 0.9928540056920678 2 Q5ST30 1
222
+ Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253] 0.517794632438755 0.0969462877252003 0.9227690496128818 1.0 0.9928540056920678 2 Q9UN37 1
223
+ Translation initiation factor IF2/IF5 domain [IPR002735] 0.5140023337222939 0.0930257636643827 0.925883093522448 1.0 0.9928540056920678 2 P20042 1
224
+ Extended synaptotagmin, C2A domain [IPR037733] 0.5119603267211292 0.090974311265484 0.9275130030351528 1.0 0.9928540056920678 2 A0FGR8 1
225
+ Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468] 0.5119603267211292 0.090974311265484 0.9275130030351528 1.0 0.9928540056920678 2 A0FGR8 1
226
+ Extended synaptotagmin, C-terminal C2 domain [IPR037752] 0.5119603267211292 0.090974311265484 0.9275130030351528 1.0 0.9928540056920678 2 A0FGR8 1
227
+ Extended synaptotagmin, C2B domain [IPR037749] 0.5119603267211292 0.090974311265484 0.9275130030351528 1.0 0.9928540056920678 2 A0FGR8 1
228
+ Synaptotagmin, SMP domain [IPR039010] 0.5119603267211292 0.090974311265484 0.9275130030351528 1.0 0.9928540056920678 2 A0FGR8 1
229
+ NOPS [IPR012975] 0.3825503355704881 0.0908493314449605 0.9276123112659234 1.0 0.9928540056920678 3 P23246,Q15233 2
230
+ Xrn1, helical domain [IPR041412] 0.5113768961493759 0.0903957832756783 0.9279727074348209 1.0 0.9928540056920678 2 Q8IZH2 1
231
+ Putative 5-3 exonuclease [IPR004859] 0.5113768961493759 0.0903957832756783 0.9279727074348209 1.0 0.9928540056920678 2 Q8IZH2 1
232
+ Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211] 0.511085180863493 0.0901077813885076 0.9282015657233482 1.0 0.9928540056920678 2 P09960 1
233
+ Vps16, C-terminal [IPR006925] 0.5107934655776043 0.0898206196201466 0.9284297623317797 1.0 0.9928540056920678 2 Q9H269 1
234
+ Pleckstrin homology domain, spectrin-type [IPR001605] 0.5072928821470392 0.0864398508848275 0.9311167690388756 1.0 0.9928540056920678 2 Q01082 1
235
+ Pleckstrin homology domain 9 [IPR041681] 0.5072928821470392 0.0864398508848275 0.9311167690388756 1.0 0.9928540056920678 2 Q01082 1
236
+ DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.3482194979568082 0.0857055893923074 0.9317004587881904 1.0 0.9928540056920678 4 O60306,P42694,Q9HCE1 3
237
+ Dual specificity phosphatase, catalytic domain [IPR000340] 0.3778815290341482 0.0847291013439059 0.9324767596246912 1.0 0.9928540056920678 3 P51452,Q99956 2
238
+ Dual specificity protein phosphatase domain [IPR020422] 0.3778815290341482 0.0847291013439059 0.9324767596246912 1.0 0.9928540056920678 3 P51452,Q99956 2
239
+ Serine/threonine-protein kinase N, C2 domain [IPR037784] 0.502333722287066 0.0818539019895418 0.9347628922514966 1.0 0.9928540056920678 2 Q16513 1
240
+ Serine/threonine-protein kinase N, first HR1 domain [IPR037313] 0.502333722287066 0.0818539019895418 0.9347628922514966 1.0 0.9928540056920678 2 Q16513 1
241
+ Kinesin-like KIF1-type [IPR022140] 0.4994165694282532 0.0792658846403547 0.936821141006274 1.0 0.9928540056920678 2 O60333 1
242
+ Kinesin-associated [IPR032405] 0.4994165694282532 0.0792658846403547 0.936821141006274 1.0 0.9928540056920678 2 O60333 1
243
+ Ubiquitin system component CUE [IPR003892] 0.3609571053399575 0.0649260834110818 0.9482328528454568 1.0 0.9928540056920678 3 Q9H4L7,Q9H1I8 2
244
+ Sec24-like, trunk domain [IPR041742] 0.3339171044950447 0.0632174094255056 0.9495933817907952 1.0 0.9928540056920678 4 O95486,O95487,O94855 3
245
+ Mib-herc2 [IPR010606] 0.4722870478413226 0.0588642424552681 0.9530602390300824 1.0 0.9928540056920678 2 Q9ULT8 1
246
+ LEM-like domain [IPR013146] 0.4719953325554321 0.0586788262470976 0.953207924479659 1.0 0.9928540056920678 2 P42167 1
247
+ COMM domain [IPR017920] 0.3507440910417426 0.0547143440933543 0.956366041547522 1.0 0.9928540056920678 3 Q86X83,Q9NX08 2
248
+ Gamma tubulin complex component protein, N-terminal [IPR041470] 0.4649941656942951 0.0544299622172249 0.9565926078330064 1.0 0.9928540056920678 2 Q96CW5 1
249
+ Gamma tubulin complex component, C-terminal [IPR040457] 0.4649941656942951 0.0544299622172249 0.9565926078330064 1.0 0.9928540056920678 2 Q96CW5 1
250
+ Zinc finger, PARP-type [IPR001510] 0.4647024504084061 0.0542611564878298 0.9567270965692 1.0 0.9928540056920678 2 P09874 1
251
+ Glutathione S-transferase, C-terminal-like [IPR010987] 0.328638290804708 0.053794028812614 0.957099266950132 1.0 0.9928540056920678 14 O15217 1
252
+ Poly(ADP-ribose) polymerase, regulatory domain [IPR004102] 0.4623687281213582 0.0529338604193667 0.957784605491742 1.0 0.9928540056920678 2 P09874 1
253
+ WGR domain [IPR008893] 0.4623687281213582 0.0529338604193667 0.957784605491742 1.0 0.9928540056920678 2 P09874 1
254
+ WW domain [IPR001202] 0.3378884287417902 0.0522166734938704 0.9583560475303156 1.0 0.9928540056920678 17 Q96PU5 1
255
+ Translation elongation factor EFTu-like, domain 2 [IPR004161] 0.3108903317614316 0.0519500026127985 0.9585685317128037 1.0 0.9928540056920678 9 Q8N442,Q9Y450 2
256
+ Coatomer, WD associated region [IPR006692] 0.4600350058343166 0.051647207318527 0.9588098035074242 1.0 0.9928540056920678 2 P53621 1
257
+ ATPase, AAA-type, core [IPR003959] 0.37852983431006 0.0469064253159649 0.9625878070712924 1.0 0.9928540056920678 30 Q8WVB6,P55072,P35251,Q9Y276,Q9H078,O76031,P40937,Q96QE3,Q5T9A4,Q9NVI7,Q9Y4W6,P36776 12
258
+ Ribosomal protein/NADH dehydrogenase domain [IPR007741] 0.4364060676779528 0.0407414446448474 0.9675020209596956 1.0 0.9928540056920678 2 P82663 1
259
+ CBS domain [IPR000644] 0.3091970802919755 0.0406121908598066 0.9676050652751178 1.0 0.9928540056920678 5 Q6P4Q7,Q8NE01,P54619,P12268 4
260
+ HD/PDEase domain [IPR003607] 0.4311551925320896 0.0387962082472116 0.9690528679407038 1.0 0.9928540056920678 2 Q9Y3Z3 1
261
+ HD domain [IPR006674] 0.4311551925320896 0.0387962082472116 0.9690528679407038 1.0 0.9928540056920678 2 Q9Y3Z3 1
262
+ Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958] 0.3152364273204971 0.0385576229581638 0.9692430891292982 1.0 0.9928540056920678 4 Q9NR33,Q01658,Q9NRG0 3
263
+ RUN domain [IPR004012] 0.3303180624453032 0.0379230607767687 0.969749026430886 1.0 0.9928540056920678 3 Q96T51,Q6ZUT9 2
264
+ Pre-SET domain [IPR007728] 0.4259043173862558 0.0370064901241345 0.9704798309159086 1.0 0.9928540056920678 2 Q15047 1
265
+ Myotubularin-like phosphatase domain [IPR010569] 0.4069428238039658 0.0317084972778915 0.9747045184476644 1.0 0.994019892360369 2 Q9Y217 1
266
+ CoA-binding [IPR003781] 0.4019836639439907 0.0305914438358375 0.9755953657877234 1.0 0.994019892360369 2 P53396 1
267
+ Far upstream element-binding protein, C-terminal [IPR015096] 0.3827304550758507 0.0271311208071764 0.9783551530769796 1.0 0.994019892360369 2 Q96AE4 1
268
+ GTP binding protein, second domain [IPR031662] 0.3771878646441047 0.0263594670075184 0.9789706235490564 1.0 0.994019892360369 2 P55039 1
269
+ Target SNARE coiled-coil homology domain [IPR000727] 0.2859228971962676 0.0256478533161114 0.9795382171816036 1.0 0.994019892360369 6 Q8IZP0,Q13277,Q9UNK0,Q13190,Q86Y82 5
270
+ Serpin domain [IPR023796] 0.3101838342573801 0.0256116030958955 0.9795671311745237 1.0 0.994019892360369 3 P50454,P30740 2
271
+ XPG, N-terminal [IPR006085] 0.3710618436406059 0.0256061772421007 0.979571458960149 1.0 0.994019892360369 2 Q9UQ84 1
272
+ XPG-I domain [IPR006086] 0.3710618436406059 0.0256061772421007 0.979571458960149 1.0 0.994019892360369 2 Q9UQ84 1
273
+ Elongation factor EFG, domain V-like [IPR000640] 0.2982408933796099 0.0252848970584057 0.9798277204823682 1.0 0.994019892360369 5 Q8N442 1
274
+ Dilute domain [IPR002710] 0.3614352392065431 0.0246106742869232 0.9803655050296474 1.0 0.994019892360369 2 P55196 1
275
+ MoaB/Mog domain [IPR001453] 0.3448074679113143 0.0233412120641661 0.981378098185417 1.0 0.994019892360369 2 Q8NFF5 1
276
+ ISWI, HAND domain [IPR015194] 0.341598599766626 0.0231508042067683 0.981529980632434 1.0 0.994019892360369 2 P28370 1
277
+ SLIDE domain [IPR015195] 0.341598599766626 0.0231508042067683 0.981529980632434 1.0 0.994019892360369 2 P28370 1
278
+ 3'-5' exonuclease domain [IPR002562] 0.3363477246207714 0.0228714165293091 0.9817528407347612 1.0 0.994019892360369 2 Q9NVH0 1
279
+ Thioesterase domain [IPR006683] 0.335764294049007 0.0228426905946119 0.9817757547281184 1.0 0.994019892360369 2 Q9NPJ3 1
280
+ ABC-transporter extension domain [IPR032781] 0.3278879813302288 0.0224960720036665 0.9820522452954406 1.0 0.994019892360369 2 Q9NUQ8 1
281
+ Chaperone DnaJ, C-terminal [IPR002939] 0.2957065312800558 0.0220180500743534 0.9824335571507206 1.0 0.994019892360369 5 Q9UBS4 1
282
+ ALIX V-shaped domain [IPR025304] 0.2928821470244981 0.0216353588420376 0.9827388278497684 1.0 0.994019892360369 2 Q9H3S7 1
283
+ Domain of unknown function DUF5600 [IPR040990] 0.2922987164527353 0.0216275743068601 0.9827450375572052 1.0 0.994019892360369 2 Q9H223 1
284
+ EH domain-containing protein, N-terminal [IPR031692] 0.2922987164527353 0.0216275743068601 0.9827450375572052 1.0 0.994019892360369 2 Q9H223 1
285
+ PurM-like, C-terminal domain [IPR010918] 0.3017216224102806 0.0215340168569394 0.9828196682210972 1.0 0.994019892360369 3 O15067,P22102 2
286
+ F-box domain [IPR001810] 0.2928467153284713 0.0184549842950633 0.9852758887713042 1.0 0.9957948484379018 5 Q13309,Q14241,Q96ME1,Q9Y2K7 4
287
+ APC10/DOC domain [IPR004939] 0.2716661803326595 0.0113239676801871 0.9909649741183012 1.0 1.0 3 O75592,O95714 2
288
+ Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378] 0.2861584061598605 0.0106237554343299 0.9915236290079454 1.0 1.0 5 P36915 1
289
+ EF-hand domain [IPR002048] 0.4175649824995236 0.0041869799547716 0.9966592830986069 1.0 1.0 49 Q8IYU8,Q14257,P60660,Q9BRK5,Q96AY3,P80303,O75746,Q9NWM8,O95202,Q9UJS0,Q9Y680,P43304,Q02818,P14314,O43852,O95302 16
290
+ Aminoacyl-tRNA synthetase, class II [IPR006195] 0.2965118609461972 0.0005312925243928 0.99957608991746 1.0 1.0 14 Q6PI48,Q9BW92,P49590 3
291
+ YTH domain [IPR007275] 0.2723292469352077 0.000265107677343 0.9997884746797754 1.0 1.0 4 Q96MU7,Q9H6S0,Q9Y5A9 3
interpro_domain/selections.json ADDED
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interpro_family/advanced/idx2term.json ADDED
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1
+ {"0": "Mitochondrial carrier protein [IPR002067]"}