diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..b9bd0b1af9393e167cc5ee2f00787b8517eb0837 --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c59391c0914e57ec9caf4d1f51c1d7802b75f634af06c7f040fc1f437f504a5e +size 90449 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..7b661840f7137a64387e1b8c176acb01186bbf34 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 55, + "title": "Average number of proteins per term", + "value": 3.0 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..db56d06b16116d82b5922e231e52ddc03e02717b --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6ea2a515d0d3e4a935040208f585ffa0309828c4 --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Histidine acid phosphatase active site [IPR033379] 0.8923570595099097 2.931035033261314 0.0033783468031258 0.1698290591847988 0.0100929925509984 2 Q9NPH0 1 +Serine carboxypeptidase, serine active site [IPR018202] 0.9039976655967296 2.5767618096177047 0.0099730647694991 0.4237836554360228 0.0203155023082389 3 Q9HB40,P10619 2 +Beta-ketoacyl synthase, active site [IPR018201] 0.768669778296386 2.345931711440025 0.0189795844812734 0.6514280029549322 0.0336734563377432 2 Q9NWU1 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..490b5aeb89309e7d196dce8fb4d94a228cbe5fa4 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, cysteine active site [IPR000169]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA/RNA non-specific endonuclease, active site [IPR018524]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "BUB1", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CASP7", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CHEK1", "CHEK2", "CHUK", "CIT", "CKB", "CKMT1A*", "CLK3", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "ENDOG", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GSK3A", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "IRAK1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR2", "MTMR6", "NEK9", "NME1", "NME3", "OXCT1", "OXSM", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRPF4B", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RAF1", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SGK3", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE2T", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["ACP6", "CTSA", "OXSM", "SCPEP1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/advanced/plot_0.png b/interpro_binding_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..25bc36ccc0adc02a8cd1a10b0197608ccdd2ad0f --- /dev/null +++ b/interpro_binding_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4aa054595ba227f9c12899effa3a78690f22a27714439b8653ae714117632986 +size 191239 diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..f9b8d9436e1824305009248c5c506c37f3090ee6 --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:433d7be45ecd4da28dccf04609f5d1f7e2626afd877e2bbc8d49a0a945f8d287 +size 136694 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..8fd030b24e72f87b59b3e7fc09235dad84a6f468 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2a1f8a4db630f22b63406f0f5acf897bcd03bdf97b4491a43575d88dec2eda5c +size 84144 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..62a8dd2f78755950c7eeb7c6d3c90484a32f59ff --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +EF-Hand 1, calcium-binding site [IPR018247] 14 41 2.0194908318202773 0.0434362292686021 10.019417475728156 36.70631067961165 0.9532938980945532 0.3894555773109194 3.76037227687173 3.057484685571999 1.1082350706804749 0.3408841825650379 0.0229247663936103 0.3228460923172884 0.0423756480977277 0.0125771724555126 0.0014520664325667 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bfadb7bbaf9b7c4b4416bd46711bebe251ba3b8c --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 31, + "title": "Average number of proteins per term", + "value": 5.32258064516129 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e75b8ee5991e8b520e2b7b2c77642063045b5fb3 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9bbfc2d9072de6ee86ada0d1f8c31e17d1f29880 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,5 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.7310385064177163 2.160169933500992 0.0307595167988106 0.620354804059881 0.0529747233757293 2 O15270 1 +EF-Hand 1, calcium-binding site [IPR018247] 0.4273871187673204 2.0194908318202773 0.0434362292686021 0.747575343185606 0.0673448079085366 41 Q6NUK1,P41208,P80303,Q14257,O43852,Q96AY3,Q9BRK5,P43304,Q9NWM8,O95202,O95302,Q02818,Q9Y680,Q96D71 14 +Beta tubulin, autoregulation binding site [IPR013838] 0.6703081321686463 1.3516252116618372 0.1764952408684323 0.997569758046166 0.202642683960052 6 P04350,P07437,Q13885,P68371 4 +Peptidase M16, zinc-binding site [IPR001431] 0.588300226514902 0.9102630463023506 0.3626838020583345 0.9999991389990032 0.4015427808502989 5 Q10713,O43847 2 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..23dd3f068ddffeeeac7df761ae778e59066cab99 --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "ARG2", "AURKA", "AURKB", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CEP97", "CETN2", "CHEK1", "CHUK", "CIT", "CLK3", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MARK2", "MCCC1", "METAP2", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "NRDC", "NUCB1", "NUCB2", "OXCT1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RAF1", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SGK3", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK4", "TAOK1", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "ULK3", "UQCRC2", "USP32", "VRK1", "YES1"], "leading_proteins": ["CALU", "CETN2", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GPD2", "LETM1", "NRDC", "NUCB1", "NUCB2", "PMPCA", "RCN2", "REPS1", "SDF4", "SLC25A24", "SPTLC2", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..5b8066d37778c6b0c5c88ab0c3729c994e9fa7fc --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "ABC transporter-like, conserved site [IPR017871]", "1": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png b/interpro_conserved_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..69561573b5ac5d98c19886209cd32a8b52d9a4d6 --- /dev/null +++ b/interpro_conserved_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:42ea7f9d2a24ebde257c37620f93814586e4741cbbbccb2c32cb5c13f5c0eb67 +size 139917 diff --git a/interpro_conserved_site/basic/plot_1.png b/interpro_conserved_site/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..10b8e03d63e98030e15b2d6f62058f93c298a038 --- /dev/null +++ b/interpro_conserved_site/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a32cf432a4758d771081d61c228aba6be06539d9090175f3c38fbb26af62987b +size 150151 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..9a5e1b27d6a55c80353f043b72bc8a77d2c94a61 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41e5f087bb568d1fecb8a71d95ad3869f2593cf99f56a60aa8f2f62a08d7c506 +size 139201 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d59e60b7ac173a52efca9f7d5f7b8c026ad50c68 --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Intermediate filament protein, conserved site [IPR018039] 2 8 2.1742805112418786 0.0296840751159552 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 1.0 1.0 1.0 1.0 0.0541965943180989 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3c9d34175d31d9dccde3a9df77f907a2c38732cf --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 279, + "title": "Average number of proteins per term", + "value": 2.795698924731183 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..db9acc0d020f425adb0d1dd9f60274e2e0049c40 --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1ca3573948f82af1ac028a09f82447dd231b5637 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,30 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Haem oxygenase conserved site [IPR018207] 0.9830805134189028 3.3362259427928493 0.0008492411343357 0.2110394365527964 0.0045565053169166 2 P30519 1 +Tetraspanin, conserved site [IPR018503] 0.9635355892648756 3.2505646286781267 0.0011517608685061 0.2749585683706663 0.0056538218423255 2 O43657 1 +Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.8103850641773496 2.547622850853498 0.0108459657133381 0.952287131697411 0.0282806021871154 2 P13473 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.8929092500729463 2.528612672680476 0.0114514323804149 0.9597797177265958 0.0295828669827385 3 P04439,P55899 2 +Ribosomal protein L3, conserved site [IPR019926] 0.770128354725787 2.3530592234685845 0.0186196682736332 0.9947201618829196 0.0430181038991285 2 P09001 1 +Sterol reductase, conserved site [IPR018083] 0.8193755471257574 2.202741469015499 0.0276129756502068 0.9995953083665076 0.0574926881075201 3 O76062,Q14739 2 +Intermediate filament protein, conserved site [IPR018039] 0.7549351500952219 2.1742805112418786 0.0296840751159552 0.9997767603202794 0.0604515106376023 8 P07197,P08670 2 +Mrp, conserved site [IPR000808] 0.7281213535589252 2.145620755574413 0.0319032481319763 0.9998821485649954 0.0645000451363869 2 Q9Y5Y2 1 +Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726] 0.7071178529755032 2.0402476653093307 0.0413256644545474 0.9999923044934088 0.0773816133075082 2 Q07820 1 +Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717] 0.7071178529755032 2.0402476653093307 0.0413256644545474 0.9999923044934088 0.0773816133075082 2 Q07820 1 +Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728] 0.7071178529755032 2.0402476653093307 0.0413256644545474 0.9999923044934088 0.0773816133075082 2 Q07820 1 +Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818] 0.82174897630985 1.955006311838443 0.0505823252793806 0.9999994864412024 0.0901828388320554 5 O75874 1 +Heat shock protein Hsp90, conserved site [IPR019805] 0.7378532216268555 1.8285429302280165 0.0674681088229893 0.9999999965630728 0.1133951949494821 3 P14625 1 +Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.7354367343067381 1.6539615492896147 0.0981353254762442 0.9999999999996948 0.1519160860643514 6 Q13315,P42345,Q13535 3 +Guanylate kinase, conserved site [IPR020590] 0.6988462986601558 1.408346409900349 0.1590285194763727 1.0 0.2164339362629658 5 Q9NZW5,Q14168 2 +Syntaxin/epimorphin, conserved site [IPR006012] 0.6914428735005235 1.3748992987078972 0.1691626667349837 1.0 0.2231386512909949 5 Q9P2W9,Q13277 2 +ABC transporter-like, conserved site [IPR017871] 0.554665662131478 1.3596413527573254 0.1739434453446897 1.0 0.2257219593077602 12 P08183,O14678,Q03519,Q03518,Q9NUT2 5 +Tubulin, conserved site [IPR017975] 0.6703081321686463 1.3516252116618372 0.1764952408684323 1.0 0.2278211852319714 6 P04350,P07437,Q13885,P68371 4 +Proteasome beta-type subunit, conserved site [IPR016050] 0.5296021156317099 0.9936732959997192 0.3203819475063452 1.0 0.3819938604883346 8 P49721,P28072 2 +3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.5564058987552856 0.9656948475342392 0.3341968984976815 1.0 0.396769934812141 3 Q16836 1 +Thiosulphate sulfurtransferase, conserved site [IPR001307] 0.4775379229871731 0.8465500969995231 0.397245939218424 1.0 0.4637306152382439 2 Q16762 1 +Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.4469078179696695 0.6927639937521037 0.4884576717189377 1.0 0.552417315552257 2 P82675 1 +DnaJ domain, conserved site [IPR018253] 0.4427339640149514 0.6574465424418127 0.5108938333174438 1.0 0.571569280415414 11 Q9Y2G8,Q96KC8,Q9NVH1 3 +Thioredoxin, conserved site [IPR017937] 0.3982263661828575 0.397502252504191 0.690997125829651 1.0 0.7414930696402793 10 Q9H1E5 1 +DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.3575705867324432 0.3528311441478141 0.7242150338055608 1.0 0.7730874986387836 15 Q9H2U1,P18074,Q08211,Q7Z478,Q7L2E3,Q14562 6 +AMP-binding, conserved site [IPR020845] 0.4361999998861626 0.327056215707137 0.7436253670585913 1.0 0.7888649331153877 6 O14975,O60488,O95573,P33121 4 +Oxysterol-binding protein, conserved site [IPR018494] 0.4345834970653465 0.3213651941728545 0.7479336563649595 1.0 0.7904298868402412 6 P22059,Q9BZF1 2 +4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.3876446374986587 0.2597381340363808 0.7950657751649965 1.0 0.8293375620613793 3 P21912 1 +DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.2867561260209976 0.0921301346035008 0.9265946463113456 1.0 0.9332848603641348 2 P28340 1 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c36b068940eff7ad3a79fdd731a6e717b6075687 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANKRD13A", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ARRB2", "ARSA", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "ATR", "BAG6", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT1", "BCAT2", "BCR", "BCS1L", "BDH2", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BUD31", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CDC40", "CDH2", "CDKAL1", "CECR2", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CREBBP", "CRYZ", "CSTB", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC2", "DSG2", "DST", "DTL", "DTYMK", "DUS2", "DUS3L", "DYNLL1", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EHHADH", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP2", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FUCA1", "FUCA2", "GAA", "GALK1", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPDH2", "INA", "INTS12", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "ITGA6", "ITGAV", "IVD", "KATNB1", "KDM2A", "KDM5A", "KDSR", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MOCS1", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NET1", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD2", "NSF", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NVL", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF2", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "POU2F1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL2", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RASAL2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "REL", "RELA", "RIDA", "RIOK1", "RIOK2", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SH3RF1", "SHPRH", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STRN", "STX12", "STX18", "STX3", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TAP1", "TAP2", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLN1", "TM7SF2", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP32", "USP34", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR47", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ABCB8", "ABCD4", "ACSL1", "ACSL3", "ACSL4", "ATM", "ATR", "DHX29", "DHX30", "DHX36", "DHX8", "DHX9", "DNAJC1", "DNAJC11", "DNAJC16", "ERCC2", "FCGRT", "HADH", "HLA-A", "HMOX2", "HSP90B1", "IDH1", "LAMP2", "LBR", "MCL1", "MPP2", "MPP6", "MRPL3", "MRPS5", "MTOR", "NEFM", "NUBP2", "OSBP", "OSBPL8", "POLD1", "PSMB2", "PSMB6", "SDHB", "SLC27A2", "STX18", "STX3", "TAP1", "TAP2", "TM7SF2", "TMX4", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "VIM"]} \ No newline at end of file diff --git a/interpro_domain/advanced/idx2term.json b/interpro_domain/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..5ff2e294143072aebcf01a0854be7f08216b639c --- /dev/null +++ b/interpro_domain/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "RNA recognition motif domain [IPR000504]", "1": "EF-hand domain [IPR002048]", "2": "K Homology domain [IPR004087]", "3": "K Homology domain, type 1 [IPR004088]", "4": "ABC transporter type 1, transmembrane domain [IPR011527]"} \ No newline at end of file diff --git a/interpro_domain/advanced/plot_0.png b/interpro_domain/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..71b8e9b77e4d175d9cec8fad561bef8f9c5e9cff --- /dev/null +++ b/interpro_domain/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3fdbfd5b81d4059b40135682393dfced398299d7b4b108739ba4c95e358b2956 +size 206790 diff --git a/interpro_domain/advanced/plot_1.png b/interpro_domain/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..892c3c92415ddeec0a7a769534a8035b9e1ea9cf --- /dev/null +++ b/interpro_domain/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:64ae147e4beead9ce93d2893b8b9ad945134d647bcc6dbaf33b2c39fe9fe38dc +size 201642 diff --git a/interpro_domain/advanced/plot_2.png b/interpro_domain/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..85584022706f1e816405d4bc94c60ffd4abd9365 --- /dev/null +++ b/interpro_domain/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a57545fb43888bae531f6f81876a10a0a0b70a1ec91930d0b236c023a448ff1d +size 198130 diff --git a/interpro_domain/advanced/plot_3.png b/interpro_domain/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..2d7949cabe26a9c18e7614f3b965d4fc7fef068f --- /dev/null +++ b/interpro_domain/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0608f92367670e42ec31441d1c107a782366a6590642c137bd52cda2e69f95e8 +size 199243 diff --git a/interpro_domain/advanced/plot_4.png b/interpro_domain/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..b073325f5f8d201f405f8bc54f05c0d2df36b069 --- /dev/null +++ b/interpro_domain/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eb3bf83886d26500dc75ee80f4ca0f7c2951046e64e445258286ed53c5193ccd +size 191398 diff --git a/interpro_domain/basic/idx2term.json b/interpro_domain/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a63b422c0aea2bf4ee57b47cb22d62a60b1c03df --- /dev/null +++ b/interpro_domain/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "RNA recognition motif domain [IPR000504]", "1": "EF-hand domain [IPR002048]", "2": "K Homology domain [IPR004087]", "3": "K Homology domain, type 1 [IPR004088]", "4": "ABC transporter type 1, transmembrane domain [IPR011527]", "5": "Immunoglobulin-like domain [IPR007110]", "6": "RNA recognition motif domain, eukaryote [IPR003954]", "7": "Histidine kinase/HSP90-like ATPase [IPR003594]", "8": "Target SNARE coiled-coil homology domain [IPR000727]", "9": "ABC transporter-like, ATP-binding domain [IPR003439]", "10": "Phospholipid/glycerol acyltransferase [IPR002123]", "11": "WW domain [IPR001202]", "12": "Helicase-associated domain [IPR007502]", "13": "Domain of unknown function DUF1605 [IPR011709]", "14": "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "15": "Linker histone H1/H5, domain H15 [IPR005818]", "16": "DnaJ domain [IPR001623]"} \ No newline at end of file diff --git a/interpro_domain/basic/plot_0.png b/interpro_domain/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..9d99990a141ee13500147dc5c16c80a285a94a65 --- /dev/null +++ b/interpro_domain/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6467fec5265b7a3c418d8aeac9d1f6814eefd26a9ae7eb1e0bdc8e48ef1f95e2 +size 150934 diff --git a/interpro_domain/basic/plot_1.png b/interpro_domain/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..f162ed5e99de961570423c615a9299b43e5d157f --- /dev/null +++ b/interpro_domain/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:14e062ae81ba208fd1ac317fac9787144bb308b58df3f4155727445852d7eabd +size 135552 diff --git a/interpro_domain/basic/plot_10.png b/interpro_domain/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..eb328a093841e69ca3240117e658860e184769a2 --- /dev/null +++ b/interpro_domain/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7f68b9ad5d1731d992c56bdfc182420b6f675a61a2369ea168abb64974c92165 +size 145620 diff --git a/interpro_domain/basic/plot_11.png b/interpro_domain/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..72f4ac223a79939c9b3ce4083ed5e47cbb57683e --- /dev/null +++ b/interpro_domain/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4adc764f33665680e8f6a1e33121f85fa35f8bc61208ea4617b27c8a832b6619 +size 141570 diff --git a/interpro_domain/basic/plot_12.png b/interpro_domain/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..32700465587e4a65ae5bca0d829bf0af0cd7e28b --- /dev/null +++ b/interpro_domain/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6fd27544d8994444636da110ea9e85e0550ace8f62a2b476386c1e2dfdb602ff +size 141945 diff --git a/interpro_domain/basic/plot_13.png b/interpro_domain/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..d870ea7b733e7bddf01bac3818f486f40774b2fb --- /dev/null +++ b/interpro_domain/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:029bef9f85de2d00247c6a600fbe6410474a63113e103e7bb6b5c6420f7aa02a +size 143532 diff --git a/interpro_domain/basic/plot_14.png b/interpro_domain/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..ea9cd7e7af511d74d618d59d08917b86bd490063 --- /dev/null +++ b/interpro_domain/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1519d27cf460aa490ba944a9ff76c0c57e4a1c74ee1034ef029b8e994239d310 +size 140810 diff --git a/interpro_domain/basic/plot_15.png b/interpro_domain/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..ee5424871dfe40fcffdc894837782745d4209dfd --- /dev/null +++ b/interpro_domain/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2ce5a9e66311da3d81a61f35e905dca61c1095b02091085bcbf7da090991b204 +size 137542 diff --git a/interpro_domain/basic/plot_16.png b/interpro_domain/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..6a9546224e1b980edf57d0e68e686083935cbd95 --- /dev/null +++ b/interpro_domain/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eec095cdef2c792131b4671e844a1689c0fd4ce0be3d66305268711597cbc698 +size 132409 diff --git a/interpro_domain/basic/plot_2.png b/interpro_domain/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..ca9842d94150c1a00edf80a9a310a9ad73873cdd --- /dev/null +++ b/interpro_domain/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aa38ddbeba055a982e8dc68964312e78423cf860e143a44ea4315fe55978e1dc +size 131823 diff --git a/interpro_domain/basic/plot_3.png b/interpro_domain/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..1d1e91ec928e7355e9401477000d481bd60d0e99 --- /dev/null +++ b/interpro_domain/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:17edfc828326ac4c83b996d6ce23d679c03229ce2f4cbb97c8d159e135674634 +size 137554 diff --git a/interpro_domain/basic/plot_4.png b/interpro_domain/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..f40fa400ecab7e8564f5c61b374a953f50ce5ad6 --- /dev/null +++ b/interpro_domain/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:43622ae80638f571e8349bc7233b724da9a36628b97731492fe20ddb44bddeed +size 138875 diff --git a/interpro_domain/basic/plot_5.png b/interpro_domain/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..1153a03e21642ce3368f1ec8461bdcdd4febfb9b --- /dev/null +++ b/interpro_domain/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8b652dd0e8bdf6442665c8ff1ef70d4990faceec65d6d2e09ba1bde3b5593325 +size 134253 diff --git a/interpro_domain/basic/plot_6.png b/interpro_domain/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..43b881da9067034bab07650d4fc94400dfd4c5fa --- /dev/null +++ b/interpro_domain/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:74c8d75d8fa743af4b0aa1268fb92466595953df6a79ce0f4d183e4976dc365f +size 142452 diff --git a/interpro_domain/basic/plot_7.png b/interpro_domain/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..20c2f99daa8829c8f22f98fcb9550890f8e5356f --- /dev/null +++ b/interpro_domain/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f3f32c9221c2b94f5e6e6bdfab1373f45f9bbe06da1d6c490c02cfeb4957412e +size 138751 diff --git a/interpro_domain/basic/plot_8.png b/interpro_domain/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..b8eddad5753b689a7a616298227947dca078f0d9 --- /dev/null +++ b/interpro_domain/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4ce8b5c466cd84e51f6a5b6d2eb10d5d6713cb54217a76d2a12fef57104b2b11 +size 138800 diff --git a/interpro_domain/basic/plot_9.png b/interpro_domain/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..4175c1c9f559b914bdc3d5ef4eb7f0edb394059b --- /dev/null +++ b/interpro_domain/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0b80891b739033864596a5f44a05cc79e67332b0e9aef9f5b31efd5087a13577 +size 140015 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e48ce30f9b332ec83a06aed92594fefff3e4c2af --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e77086e1e4e71c522735b8e1bd9fd07ee06ddbd1f85b117d003f975d7ad88d6c +size 768153 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2c17a5c1febc45bf65e2db2c338dd5c5d1afcbc1 --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,10 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +RNA recognition motif domain [IPR000504] 44 124 3.040273234071063 0.0023636360944392 39.713592233009706 116.0 0.2316956716939257 0.5316884276370477 13.873754985119357 5.729331786381952 1.713447249572458 0.3950212299678106 0.0003673572460054 1.0 1.0 0.0011405349889503 4.652123751237258e-09 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 3 7 2.234429048658208 0.0254548561425311 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0002477926457577 0.0573151884822011 0.0058956460302812 0.0001472775053537 0.0020033682110678 +Intermediate filament, rod domain [IPR039008] 2 8 2.1742805112418786 0.0296840751159552 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 1.0 1.0 1.0 1.0 0.0888008652079453 +EF-hand domain [IPR002048] 18 49 2.1508917680225847 0.0314847434457419 12.385922330097088 43.512135922330096 1.0171858714399242 0.3947118087831401 4.608360476919044 4.087317384177653 1.201458704248258 0.3652478399429377 0.0217955460367635 0.3898210156701354 0.074977025310764 0.0111193401215375 0.0010723609662722 +K Homology domain [IPR004087] 8 23 2.118526245213691 0.0341305246119982 8.029126213592233 22.796116504854368 0.328818420881894 0.600646587147133 4.351556602822176 1.3994397166034702 0.8923876485619237 0.3352669927506027 0.0129229397102748 0.1499686155438198 0.0412914524019695 0.0081443152876 0.0001399534495659 +K Homology domain, type 1 [IPR004088] 8 23 2.06665865229459 0.0387663298841511 8.5 23.218446601941743 0.4539576731478794 0.576935027430011 4.690674491420825 1.6401661988255969 0.9187340965418598 0.3398774289684012 0.014331659651373 0.1541506060207377 0.0435975481844182 0.0090567827451286 0.0001753252601336 +ABC transporter type 1, transmembrane domain [IPR011527] 5 8 2.0359384062619497 0.0417565406200859 2.3689320388349513 6.349514563106796 0.6640264147492347 0.3307390797434538 1.7803691733569 2.1393617497725477 1.1694677427725269 0.279101120079799 0.0006394246968973 1.0 1.0 0.0052676758380378 0.0049176108076387 +Zinc finger, RanBP2-type [IPR001876] 4 9 2.0076734377577776 0.0446780050452488 3.2742718446601944 8.616504854368932 0.6239078002715212 0.4100405386528319 1.463145369641179 0.7330740021954685 1.0299872364022182 0.3121093098016552 0.0024564584457719 1.0 1.0 0.0920739634299925 0.0028394369313259 +Immunoglobulin C1-set [IPR003597] 3 5 1.970046422682263 0.0488330504125507 1.5364077669902914 3.2645631067961167 0.6739064474228705 0.388919959347808 0.9507966556146606 0.908645932409072 1.1616974926444357 0.3094128568625329 0.0975023582906358 1.0 1.0 0.0773660358903978 0.0119688845689888 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..c5225712167f580058b3f2cf2015d64aaed86c65 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 2840, + "title": "Average number of proteins per term", + "value": 2.225704225352113 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..4be08276435ea60b76ea05e277eb058536ce51e8 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0bd1ab2c1c1c49de63f216b82ea0c52a3039c8dc --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,248 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.9711201866977834 3.283910031346742 0.0010237759900144 0.9454704844816592 0.006575004781375 2 P51114 1 +Phospholipase D/Transphosphatidylase [IPR001736] 0.9524504084014012 3.2015900776514634 0.0013667133645705 0.9794340976496004 0.0078478597943593 2 Q8IV08 1 +CARG-binding factor, N-terminal [IPR012956] 0.9507001166861146 3.193831142866651 0.0014039821285176 0.9815023378119214 0.0078478597943593 2 Q14103 1 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.9434072345390898 3.1614251061890912 0.0015699918602369 0.9884639766292036 0.0082040565485985 2 O60506 1 +BRICHOS domain [IPR007084] 0.9346557759626613 3.122372712007183 0.0017939966355042 0.9939003633800582 0.0086758078583411 2 Q9Y287 1 +RNA recognition motif domain [IPR000504] 0.4066500758125715 3.040273234071063 0.0023636360944392 0.9987942726118936 0.0104645390716653 124 Q14011,P78332,P14866,P52756,P11940,Q14103,Q01844,P98175,Q9BWF3,P98179,P51991,Q99729,Q13151,Q13595,Q01085,P07910,Q15427,Q9P2N5,Q96DH6,O60506,A0AV96,P52597,O43390,P55795,P62995,P31483,Q9UKA9,P23246,P43243,Q96EP5,P31943,P26368,Q9UKM9,P22626,P31942,P23588,Q92804,P38159,Q76FK4,P35637,Q96PK6,O14979,Q9UHX1,Q01081 44 +Acyl-CoA oxidase, C-terminal [IPR002655] 0.9072345390898484 2.998826469486689 0.0027102162113339 0.999550539781774 0.0113212476872776 2 O15254 1 +Reticulon [IPR003388] 0.8955659276546021 2.945702482722128 0.0032222217057014 0.9998954541518088 0.0126184431342026 2 O95197 1 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.8841890315052523 2.8935854444742555 0.003808706479444 0.9999803489094568 0.0139211408000273 2 P13674 1 +SUN coiled coil domain 2 [IPR040994] 0.8745624270711791 2.849236703007834 0.0043824262534186 0.9999961730504644 0.0154226648819194 2 O94901 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.8710618436406079 2.833052803827757 0.0046105769177475 0.9999980039036026 0.0160269748425986 2 Q5T9A4 1 +Far upstream element-binding protein, C-terminal [IPR015096] 0.8646441073512273 2.8033029006065533 0.0050582138944044 0.9999994436019553 0.0170520036121706 2 Q96AE4 1 +Fatty acid hydroxylase [IPR006694] 0.8640606767794514 2.8005932557734146 0.0051008766828015 0.9999995073972664 0.0170907606335535 2 Q15800 1 +FF domain [IPR002713] 0.8521003500583442 2.7448571818480834 0.0060537236665587 0.9999999675908726 0.019317500239356 2 O14776 1 +Fxr1, tudor domain [IPR041560] 0.9413481178873606 2.737047495117344 0.0061993341985262 0.9999999786221136 0.0195189679864906 3 P51116,P51114 2 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.9413481178873606 2.737047495117344 0.0061993341985262 0.9999999786221136 0.0195189679864906 3 P51116,P51114 2 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.9413481178873606 2.737047495117344 0.0061993341985262 0.9999999786221136 0.0195189679864906 3 P51116,P51114 2 +Agenet-like domain [IPR008395] 0.9413481178873606 2.737047495117344 0.0061993341985262 0.9999999786221136 0.0195189679864906 3 P51116,P51114 2 +MD-2-related lipid-recognition domain [IPR003172] 0.8488914819136384 2.7298423014201925 0.0063364628479678 0.9999999855534552 0.0197970896460161 2 P17900 1 +Coagulation factor 5/8 C-terminal domain [IPR000421] 0.8485997666277705 2.728476022559896 0.0063627715680467 0.999999986599915 0.0198574409376404 2 Q08431 1 +Tim44-like domain [IPR007379] 0.8334305717619623 2.6571323703404346 0.0078808492285125 0.9999999998257048 0.0223753233279922 2 Q9BRJ2 1 +SLC12A transporter, C-terminal [IPR018491] 0.8264294049008157 2.624007182157026 0.0086901952624562 0.9999999999828328 0.0240313091970553 2 P55011 1 +Amino acid permease/ SLC12A domain [IPR004841] 0.8264294049008157 2.624007182157026 0.0086901952624562 0.9999999999828328 0.0240313091970553 2 P55011 1 +CNNM, transmembrane domain [IPR002550] 0.8255542590431768 2.619857741487803 0.0087966454092425 0.9999999999873456 0.0241696485714251 2 Q8NE01 1 +Ion transporter-like, CBS domain [IPR044751] 0.8255542590431768 2.619857741487803 0.0087966454092425 0.9999999999873456 0.0241696485714251 2 Q8NE01 1 +Zinc finger, CHHC-type [IPR012996] 0.907791070907494 2.593174368381372 0.0095094543860827 0.9999999999983596 0.0253097201962222 3 P31943,P55795 2 +Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906] 0.8159276546091014 2.574084676755129 0.0100505672205344 0.9999999999996524 0.0262832512949519 2 Q15418 1 +RBM3/CIRBP, RNA recognition motif [IPR034278] 0.8130105017502961 2.5601672160502593 0.0104621809858376 0.9999999999998932 0.0270606502730226 2 P98179 1 +Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120] 0.8092182030338286 2.542041902990104 0.0110206960321392 0.9999999999999786 0.0281210931997085 2 Q96K12 1 +Fatty acyl-CoA reductase, C-terminal [IPR033640] 0.8092182030338286 2.542041902990104 0.0110206960321392 0.9999999999999786 0.0281210931997085 2 Q96K12 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.885030639042895 2.494243671551907 0.0126225858394297 0.9999999999999998 0.0310990943671938 3 P01889,P04439 2 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.885030639042895 2.494243671551907 0.0126225858394297 0.9999999999999998 0.0310990943671938 3 P01889,P04439 2 +Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.8844470382258449 2.4916926005377498 0.0127136016790663 1.0 0.031131292282456 3 Q32P28,P13674 2 +Cysteine-rich flanking region, C-terminal [IPR000483] 0.7838389731621922 2.419791134238807 0.0155294240437338 1.0 0.0360617860050727 2 Q13641 1 +Leucine-rich repeat N-terminal domain [IPR000372] 0.7838389731621922 2.419791134238807 0.0155294240437338 1.0 0.0360617860050727 2 Q13641 1 +Legume-like lectin [IPR005052] 0.7812135355892644 2.407050038389887 0.0160819662152107 1.0 0.0369820113774886 2 P49257 1 +Potentiating neddylation domain [IPR005176] 0.8636501374980918 2.4003137979678075 0.016381022424311 1.0 0.0374875936221139 3 Q92564 1 +Potassium channel tetramerisation-type BTB domain [IPR003131] 0.7756709451575245 2.3800940406651776 0.0173082203296606 1.0 0.0389812416623601 2 Q96CX2 1 +Survival motor neuron [IPR010304] 0.773045507584601 2.367297893515124 0.017918503702023 1.0 0.0399439172007421 2 Q16637 1 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8546833965567391 2.360633094045106 0.0182437705306757 1.0 0.0402703101282019 3 Q15629,Q96G23 2 +Beta-ketoacyl synthase, N-terminal [IPR014030] 0.768669778296386 2.345931711440025 0.0189795844812734 1.0 0.0411160369792864 2 Q9NWU1 1 +Polyketide synthase, beta-ketoacyl synthase domain [IPR020841] 0.768669778296386 2.345931711440025 0.0189795844812734 1.0 0.0411160369792864 2 Q9NWU1 1 +Beta-ketoacyl synthase, C-terminal [IPR014031] 0.768669778296386 2.345931711440025 0.0189795844812734 1.0 0.0411160369792864 2 Q9NWU1 1 +Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141] 0.757876312718779 2.293019000517079 0.0218469110755443 1.0 0.0460949454682253 2 P20020 1 +Tim10-like [IPR004217] 0.8348409687773409 2.2722218477979466 0.0230731143303388 1.0 0.0479003250717561 3 Q9Y5J9,Q9Y5L4 2 +Cyclin, N-terminal [IPR006671] 0.7473745624270727 2.241251379249401 0.0250097964428093 1.0 0.051099152444301 2 O95067 1 +Cyclin, C-terminal domain [IPR004367] 0.7473745624270727 2.241251379249401 0.0250097964428093 1.0 0.051099152444301 2 O95067 1 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.8162712200602461 2.2344290486582077 0.0254548561425311 1.0 0.0518220727202785 7 Q8WUJ1,O15173,O43169 3 +Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.8220017508024409 2.214575095542496 0.0267892429907758 1.0 0.0536919196145402 3 Q9BUJ2,Q1KMD3 2 +Intermediate filament, rod domain [IPR039008] 0.7549351500952219 2.1742805112418786 0.0296840751159552 1.0 0.0577812017335935 8 P07197,P08670 2 +OCRE domain [IPR041591] 0.812664137729783 2.172435167819148 0.0298228548046732 1.0 0.0580115805789535 3 P98175,P52756 2 +EF-hand domain [IPR002048] 0.4189436688807909 2.1508917680225847 0.0314847434457419 1.0 0.0605804006679587 49 Q6NUK1,P41208,P80303,Q14257,O43852,Q96AY3,Q9H223,P43304,Q9BRK5,Q9NWM8,O75071,O95202,O95302,Q02818,Q9Y680,Q8NF37,Q8IYU8,Q96D71 18 +MHC class I-like antigen recognition-like [IPR011161] 0.8852889667250365 2.1392055320979617 0.0324190263571333 1.0 0.0620000234708812 4 P01889,P04439,P55899 3 +K Homology domain [IPR004087] 0.5502085075111194 2.118526245213691 0.0341305246119982 1.0 0.06462045993205 23 P61978,P51116,Q06787,Q9Y2W6,Q92945,P51114,Q96AE4,Q07666 8 +K Homology domain, type 1 [IPR004088] 0.5432989374210301 2.06665865229459 0.0387663298841511 1.0 0.0715841202022037 23 P61978,P51116,Q06787,Q9Y2W6,Q92945,P51114,Q96AE4,Q07666 8 +Glycosyl hydrolase family 38, C-terminal [IPR011682] 0.7100350058343066 2.0549471360705964 0.0398841109949827 1.0 0.0729551280348863 2 Q16706 1 +Glycoside hydrolase family 38, central domain [IPR015341] 0.7100350058343066 2.0549471360705964 0.0398841109949827 1.0 0.0729551280348863 2 Q16706 1 +Glycoside hydrolase family 38, N-terminal domain [IPR000602] 0.7100350058343066 2.0549471360705964 0.0398841109949827 1.0 0.0729551280348863 2 Q16706 1 +ABC transporter type 1, transmembrane domain [IPR011527] 0.7276158051171654 2.0359384062619497 0.0417565406200859 1.0 0.0755903580458297 8 P08183,O14678,Q03519,Q03518,Q9NUT2 5 +Zinc finger, RanBP2-type [IPR001876] 0.7086774498963556 2.0076734377577776 0.0446780050452488 1.0 0.0794065329090055 9 Q92804,P98175,P35637,Q01844 4 +Zinc finger, MYND-type [IPR002893] 0.7744197289095939 1.9979899018865408 0.0457177549152709 1.0 0.0805949248661511 3 Q9H7B4 1 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.7735812176830459 1.994132583948965 0.0461375671876553 1.0 0.0809537003443517 3 Q7L576 1 +Immunoglobulin C1-set [IPR003597] 0.8252019376655577 1.970046422682263 0.0488330504125507 1.0 0.0841540431866771 5 P01889,P04439,P55899 3 +Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481] 0.6922403733955733 1.9649647210492829 0.0494183208932441 1.0 0.0849564354339064 2 Q96KP1 1 +Isopropylmalate dehydrogenase-like domain [IPR024084] 0.82174897630985 1.955006311838443 0.0505823252793806 1.0 0.0864567060530678 5 O75874 1 +Immunoglobulin-like domain [IPR007110] 0.6551366320062484 1.9465294575724377 0.0515911729898876 1.0 0.0873696668403583 12 P10321,P55899,P01889,P35613,P04439 5 +Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955] 0.7624744674642364 1.9429114017248337 0.0520268640837113 1.0 0.0878455969070988 3 Q15118,Q15120 2 +Histidine kinase domain [IPR005467] 0.7624744674642364 1.9429114017248337 0.0520268640837113 1.0 0.0878455969070988 3 Q15118,Q15120 2 +Intermediate filament head, DNA-binding domain [IPR006821] 0.8334461445683874 1.921553264961466 0.0546619940050541 1.0 0.0908899666126192 4 P07197,P08670 2 +ERAP1-like C-terminal domain [IPR024571] 0.8307063631056422 1.9099296634714356 0.0561422701307345 1.0 0.0927000274251664 4 Q9UIQ6,Q9NZ08,Q6P179 3 +Ribosomal Proteins L2, RNA binding domain [IPR022666] 0.6764877479579983 1.88469331103136 0.0594712559712582 1.0 0.0971238452894614 2 Q5T653 1 +Ribosomal protein L2, C-terminal [IPR022669] 0.6764877479579983 1.88469331103136 0.0594712559712582 1.0 0.0971238452894614 2 Q5T653 1 +Mad3/Bub1 homology region 1 [IPR013212] 0.6753208868144622 1.8787250469407144 0.0602820459811914 1.0 0.0981094616542027 2 O43683 1 +ELMO domain [IPR006816] 0.6732788798133076 1.868273359714539 0.0617239779533194 1.0 0.0997701180349613 2 Q8IZ81 1 +N-acetylgalactosaminyltransferase [IPR045885] 0.7414648380507554 1.8453880096287296 0.064981116092508 1.0 0.1036777357880464 3 Q8N4A0,Q10472 2 +RNA recognition motif domain, eukaryote [IPR003954] 0.6093569615407869 1.841821331575644 0.0655012887303756 1.0 0.1042149355710178 14 Q14011,P31483,P11940,Q01085,O95628,Q9UHX1,Q01081,P38159 8 +LEM-like domain [IPR013146] 0.6642357059509982 1.8218784792721217 0.068473426387843 1.0 0.1075342601436276 2 P42166 1 +Putative 5-3 exonuclease [IPR004859] 0.6616102683780669 1.8083763508824549 0.0705479460585889 1.0 0.1096640212404995 2 Q9H0D6 1 +Xrn1, helical domain [IPR041412] 0.6616102683780669 1.8083763508824549 0.0705479460585889 1.0 0.1096640212404995 2 Q9H0D6 1 +Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.7250212277730701 1.7995695350111782 0.0719286351216257 1.0 0.111043785925676 7 Q32P28,P13674,O60568 3 +Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.7250212277730701 1.7995695350111782 0.0719286351216257 1.0 0.111043785925676 7 Q32P28,P13674,O60568 3 +Sec63 domain [IPR004179] 0.7311083615729707 1.7970230190758574 0.0723319654521712 1.0 0.1114006409350142 3 Q9UGP8 1 +Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.6805099732979153 1.793229664346597 0.0729362086413059 1.0 0.1122095517558552 8 Q13315,P42345,Q9BTU6,Q13535 4 +Major facilitator superfamily domain [IPR020846] 0.8023934617629684 1.7891439785749623 0.073591631057118 1.0 0.1129632181710683 4 P53985,Q9H2V7,Q14728 3 +Histidine kinase/HSP90-like ATPase [IPR003594] 0.6466065010534586 1.7451862822163748 0.0809524482854624 1.0 0.1213859309032277 10 Q15120,Q15118,Q58FF6,P14625,O14874,P07900 6 +Importin-alpha, importin-beta-binding domain [IPR002652] 0.771941115181525 1.7359038753423546 0.0825808324652697 1.0 0.1233716802742587 5 P52294 1 +Pleckstrin homology domain 9 [IPR041681] 0.6455659276546171 1.7255576813974436 0.0844270182095594 1.0 0.1249204823684127 2 O15020 1 +Pleckstrin homology domain, spectrin-type [IPR001605] 0.6455659276546171 1.7255576813974436 0.0844270182095594 1.0 0.1249204823684127 2 O15020 1 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7585401459853727 1.6763176677222975 0.0936759860563121 1.0 0.1348546508924997 5 P20020,Q9HD20,P05023,P16615 4 +FAD-binding domain, ferredoxin reductase-type [IPR017927] 0.7037181664963249 1.668253288241207 0.0952654565286086 1.0 0.1364366598796008 3 P16435 1 +Oxidoreductase FAD/NAD(P)-binding [IPR001433] 0.7037181664963249 1.668253288241207 0.0952654565286086 1.0 0.1364366598796008 3 P16435 1 +Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709] 0.7037181664963249 1.668253288241207 0.0952654565286086 1.0 0.1364366598796008 3 P16435 1 +Ribosomal protein S7 domain [IPR023798] 0.6338973162193617 1.6650143931256245 0.0959098843225261 1.0 0.1371716805299924 2 P46782 1 +Ribosomal protein L18e/L15P [IPR021131] 0.7000259355253572 1.6508067494018737 0.0987780415246613 1.0 0.140692850703674 3 P46776 1 +Elp3/MiaB/NifB [IPR006638] 0.6999703074870542 1.6505437460663954 0.0988317736457147 1.0 0.140692850703674 3 Q5VV42 1 +Radical SAM [IPR007197] 0.6999703074870542 1.6505437460663954 0.0988317736457147 1.0 0.140692850703674 3 Q5VV42 1 +Zinc finger C2H2 AKAP95-type [IPR034736] 0.6959439743215512 1.6314961202084215 0.1027856778449436 1.0 0.1453018044199302 3 Q5BKZ1,Q9ULX6 2 +Peptidase M3A/M3B catalytic domain [IPR001567] 0.6950431814557438 1.6272316031165177 0.1036879180904453 1.0 0.1459772050411245 3 Q99797 1 +Peptidase M41 [IPR000642] 0.6266044340723533 1.6270519905504843 0.1037260562580948 1.0 0.1459772050411245 2 Q9Y4W6 1 +Cation-transporting P-type ATPase, N-terminal [IPR004014] 0.7583187390542685 1.5989159571981102 0.109839277894989 1.0 0.1533749139479367 4 P20020,P05023,P16615 3 +Cation-transporting P-type ATPase, C-terminal [IPR006068] 0.7583187390542685 1.5989159571981102 0.109839277894989 1.0 0.1533749139479367 4 P20020,P05023,P16615 3 +Syntaxin, N-terminal domain [IPR006011] 0.6833965567551765 1.571997731739109 0.1159510772616667 1.0 0.1590745749990054 3 Q86Y82,Q13277 2 +NOPS [IPR012975] 0.6816457543040637 1.56367977575442 0.1178927895792831 1.0 0.1605829843669852 3 P23246,Q8WXF1 2 +Peptidase M28 [IPR007484] 0.6140606767794694 1.561555301968275 0.1183927863064613 1.0 0.1611067299550352 2 Q969V3 1 +PIK-related kinase [IPR014009] 0.7290510948904836 1.5443920728480216 0.12249337928085 1.0 0.1651073550819241 5 Q13315,P42345,P78527,Q13535 4 +PIK-related kinase, FAT [IPR003151] 0.7290510948904836 1.5443920728480216 0.12249337928085 1.0 0.1651073550819241 5 Q13315,P42345,P78527,Q13535 4 +FATC domain [IPR003152] 0.7290510948904836 1.5443920728480216 0.12249337928085 1.0 0.1651073550819241 5 Q13315,P42345,P78527,Q13535 4 +Patatin-like phospholipase domain [IPR002641] 0.6766233262175514 1.539798424085014 0.1236094962026039 1.0 0.1665327178441154 3 Q9NP80 1 +ISWI, HAND domain [IPR015194] 0.6088098016336081 1.534069109771541 0.12501265175457 1.0 0.1676200806826494 2 P28370 1 +SLIDE domain [IPR015195] 0.6088098016336081 1.534069109771541 0.12501265175457 1.0 0.1676200806826494 2 P28370 1 +Glycosyltransferase 2-like [IPR001173] 0.7416812609456884 1.5265199814143613 0.1268804180876099 1.0 0.1693328888011336 4 O60762,Q8N4A0,Q10472 3 +RGS domain [IPR016137] 0.6728796762186321 1.521979006537368 0.1280143410221301 1.0 0.1705256700294792 3 O43572 1 +FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.590480453136927 1.4993848274206183 0.1337738274185143 1.0 0.1761408145116107 11 Q9Y680,Q9NWM8,O95302 3 +FAD dependent oxidoreductase [IPR006076] 0.727670753064783 1.465356267452115 0.1428237424226968 1.0 0.1856729369831557 4 Q9H9P8,Q96CU9,P43304 3 +L27 domain, C-terminal [IPR014775] 0.7240612655255217 1.4495736649867992 0.1471774442355558 1.0 0.1899927007404447 4 Q9NZW5,Q14168 2 +Peptidase M16, C-terminal [IPR007863] 0.6536389861880477 1.44873725877237 0.1474109711417845 1.0 0.1901213251783234 7 Q10713,Q5JRX3,P31930,O43847 4 +Peptidase M16, N-terminal [IPR011765] 0.6536389861880477 1.44873725877237 0.1474109711417845 1.0 0.1901213251783234 7 Q10713,Q5JRX3,P31930,O43847 4 +Pentacotripeptide-repeat region of PRORP [IPR033443] 0.5892648774795909 1.4314608166620508 0.1522981891589159 1.0 0.1943940931286836 2 O75127 1 +Target SNARE coiled-coil homology domain [IPR000727] 0.6839953271028101 1.4154735097543656 0.1569297099709361 1.0 0.1989644537131512 6 Q86Y82,Q13190,Q8IZP0,Q13277,Q9UNK0 5 +v-SNARE, coiled-coil homology domain [IPR042855] 0.64867230814124 1.4064291080107187 0.1595967418565167 1.0 0.2016257770785176 3 P51809,O15498 2 +Longin domain [IPR010908] 0.64867230814124 1.4064291080107187 0.1595967418565167 1.0 0.2016257770785176 3 P51809,O15498 2 +ABC transporter-like, ATP-binding domain [IPR003439] 0.554665662131478 1.3596413527573254 0.1739434453446897 1.0 0.2156260954949449 12 P08183,O14678,Q03519,Q03518,Q9NUT2 5 +BTB/POZ domain [IPR000210] 0.7033537065978601 1.3588733746672106 0.1741867172043503 1.0 0.2156452819792305 4 Q08380,Q96CX2 2 +Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.6703081321686463 1.3516252116618372 0.1764952408684323 1.0 0.2173662116506279 6 P04350,P07437,Q13885,P68371 4 +Tubulin/FtsZ, GTPase domain [IPR003008] 0.6703081321686463 1.3516252116618372 0.1764952408684323 1.0 0.2173662116506279 6 P04350,P07437,Q13885,P68371 4 +SUN domain [IPR012919] 0.6359040648468688 1.3453119925598882 0.1785245023531405 1.0 0.2192948039285982 3 O94901 1 +Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038] 0.6822065595136331 1.3331346616826012 0.1824876163880107 1.0 0.2222404933713337 5 P55769 1 +Ubiquitin-like domain, USP-type [IPR028135] 0.6327929985188756 1.330409222281724 0.1833834776649925 1.0 0.2228536913002048 3 Q13107 1 +Heat shock protein Hsp90, N-terminal [IPR020575] 0.6776489007317615 1.3125148002022693 0.189346495665291 1.0 0.2285967393418824 5 Q58FF6,P14625,P07900 3 +YTH domain [IPR007275] 0.6893660419581306 1.2975041984666975 0.1944577614697025 1.0 0.2332203304732838 4 Q9H6S0,Q96MU7 2 +GUCT [IPR012562] 0.5306301050175187 1.122512473001526 0.2616446072438312 1.0 0.3045371658083937 2 Q9NR30 1 +MRH domain [IPR044865] 0.6464418830958094 1.109261321593644 0.2673174655712089 1.0 0.3102553648825192 4 Q13438 1 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.6182056916386808 1.108319258509603 0.2677239611053128 1.0 0.310341244709832 6 Q9UIQ6,Q9NZ08,Q6P179 3 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.6182056916386808 1.108319258509603 0.2677239611053128 1.0 0.310341244709832 6 Q9UIQ6,Q9NZ08,Q6P179 3 +Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346] 0.5827254158155917 1.090718615852255 0.2753967166500866 1.0 0.3187150266040122 3 Q93009,Q9Y4E8 2 +Phospholipid/glycerol acyltransferase [IPR002123] 0.576439664651565 1.064748434477531 0.2869897856497472 1.0 0.3311869123304681 7 Q6UWP7,Q9NUQ2,Q99943,O15228,Q8NF37 5 +CTP synthase, N-terminal [IPR017456] 0.5134189031505424 1.032253816321021 0.3019532301383243 1.0 0.3460642347025186 2 P17812 1 +CTP synthase GATase domain [IPR033828] 0.5134189031505424 1.032253816321021 0.3019532301383243 1.0 0.3460642347025186 2 P17812 1 +Acyltransferase, C-terminal domain [IPR032098] 0.5667056019859965 1.0144706132465495 0.3103582448992519 1.0 0.3546951370277164 3 Q9NUQ2 1 +Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422] 0.5090431738623267 1.009397431474185 0.3127840697945965 1.0 0.3573237160968037 2 O75146 1 +Band 7 domain [IPR001107] 0.5649527125917582 1.0079050645852845 0.3135000400572669 1.0 0.3579976331976832 7 Q99623,O75477 2 +Tudor domain [IPR002999] 0.5317453314839449 1.0050089714444206 0.3148925299344061 1.0 0.3594432415649973 8 Q9Y2W6,Q16637,Q14739 3 +Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543] 0.5075845974329138 1.0017887194662571 0.3164456465616041 1.0 0.3607810663327803 2 Q13555 1 +3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.5564058987552856 0.9656948475342392 0.3341968984976815 1.0 0.3791926455187437 3 Q16836 1 +3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.5564058987552856 0.9656948475342392 0.3341968984976815 1.0 0.3791926455187437 3 Q16836 1 +Vicinal oxygen chelate (VOC) domain [IPR037523] 0.5005834305717711 0.9653450738565648 0.334372002581162 1.0 0.3792398112342253 2 Q04760 1 +ZU5 domain [IPR000906] 0.4982497082847302 0.9532285151684934 0.3404743015847704 1.0 0.385698849820801 2 Q07157 1 +Coatomer, WD associated region [IPR006692] 0.4947491248541613 0.9350860132554348 0.3497439740496544 1.0 0.3952668290983404 2 P35606 1 +Lamin tail domain [IPR001322] 0.5481862470660986 0.9269491482522244 0.3539529374034926 1.0 0.3993747883297255 3 Q03252 1 +Ricin B, lectin domain [IPR000772] 0.5946119065433113 0.8844214759845382 0.3764687340170567 1.0 0.4241059915146533 4 Q8N4A0 1 +SET domain [IPR001214] 0.4923148154405091 0.8841348531607667 0.3766234207291157 1.0 0.4241120201707726 10 Q9H7B4,O96028 2 +GRAM domain [IPR004182] 0.5336747046247867 0.8590294531592086 0.3903242665944346 1.0 0.4388443852447325 3 Q66K14 1 +Protein phosphatase 1 binding domain [IPR029334] 0.4784130688448121 0.8510216108945006 0.3947573481066571 1.0 0.4434774005628584 2 P46013 1 +WW domain [IPR001202] 0.4200236570729468 0.8359640564348522 0.4031751241386341 1.0 0.45257602867736 17 O14776,Q96J02,P46934,Q96PU5,O75400 5 +Guanylate kinase-like domain [IPR008144] 0.5288577471265438 0.8312863358986508 0.4058118918406841 1.0 0.454996357215769 7 Q9NZW5,Q14168 2 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.5288577471265438 0.8312863358986508 0.4058118918406841 1.0 0.454996357215769 7 Q9NZW5,Q14168 2 +Suppressor of forked [IPR008847] 0.4737456242707251 0.8272161410818296 0.4081145645327906 1.0 0.4572171058276628 2 Q12996 1 +Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187] 0.4717036172695587 0.8168353756935728 0.4140225129255017 1.0 0.4632876031160066 2 O75694 1 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.5505827232358997 0.7973481352234579 0.4252488719443459 1.0 0.4745409808730618 6 Q9H223,O60313 2 +Dynamin, N-terminal [IPR045063] 0.5505827232358997 0.7973481352234579 0.4252488719443459 1.0 0.4745409808730618 6 Q9H223,O60313 2 +Helicase-associated domain [IPR007502] 0.4485962054244211 0.7876791143644634 0.430884425199648 1.0 0.4797583939548434 13 Q9H2U1,Q9H6S0,Q08211,Q7Z478,Q7L2E3,Q14562,Q92620 7 +Domain of unknown function DUF1605 [IPR011709] 0.4485962054244211 0.7876791143644634 0.430884425199648 1.0 0.4797583939548434 13 Q9H2U1,Q9H6S0,Q08211,Q7Z478,Q7L2E3,Q14562,Q92620 7 +CELF1/2, RNA recognition motif 3 [IPR034199] 0.4658693115519336 0.7872990280805893 0.4311068385115353 1.0 0.4797583939548434 2 Q92879 1 +CELF1/2, RNA recognition motif 1 [IPR034196] 0.4658693115519336 0.7872990280805893 0.4311068385115353 1.0 0.4797583939548434 2 Q92879 1 +CELF1/2, RNA recognition motif 2 [IPR034198] 0.4658693115519336 0.7872990280805893 0.4311068385115353 1.0 0.4797583939548434 2 Q92879 1 +Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036] 0.465285880980177 0.7843558959247748 0.4328313097631155 1.0 0.480547662129495 2 Q96C36 1 +Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939] 0.465285880980177 0.7843558959247748 0.4328313097631155 1.0 0.480547662129495 2 Q96C36 1 +Domain of unknown function DUF3517 [IPR021905] 0.5143259677841696 0.7697030354001515 0.4414760691099022 1.0 0.4888078114121335 3 Q70CQ2 1 +CBS domain [IPR000644] 0.5547094600394273 0.7629376721790648 0.4455005678612167 1.0 0.493071556011635 5 Q8NE01,P51798 2 +Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615] 0.5513089355050691 0.7482592213820891 0.4543038161324233 1.0 0.5008629028789139 5 Q8NFA0,Q13107 2 +GOLD domain [IPR009038] 0.5094205460667056 0.7381438922783308 0.4604270138817887 1.0 0.5070231560388834 7 P49755,Q9Y3B3,Q15363 3 +Glutathione S-transferase, N-terminal [IPR004045] 0.4725058524969887 0.7345162713740557 0.462634146988842 1.0 0.5092561928094229 9 O15217,Q8TB36 2 +GTP binding domain [IPR006073] 0.4305655027720081 0.7294565564801034 0.4657224329558009 1.0 0.5124570746200987 14 Q8N3Z3,Q9NTK5 2 +Class I myosin, motor domain [IPR036072] 0.5562269772495259 0.7223896456661929 0.470054951098747 1.0 0.5166238626627097 4 O94832 1 +Class I myosin tail homology domain [IPR010926] 0.5562269772495259 0.7223896456661929 0.470054951098747 1.0 0.5166238626627097 4 O94832 1 +Aminotransferase, class I/classII [IPR004839] 0.5052786731505456 0.7185412168898594 0.4724236435313564 1.0 0.5190263627191692 7 O15269 1 +Immunoglobulin subtype [IPR003599] 0.5016809359120649 0.7015936113772836 0.4829326369185112 1.0 0.5303111943167237 7 P35613,P78310 2 +Ribosomal protein S5, C-terminal [IPR005324] 0.4469078179696695 0.6927639937521037 0.4884576717189377 1.0 0.5358129732258722 2 P82675 1 +Ribosomal protein S5, N-terminal [IPR013810] 0.4469078179696695 0.6927639937521037 0.4884576717189377 1.0 0.5358129732258722 2 P82675 1 +tRNA-guanine(15) transglycosylase-like [IPR002616] 0.4407817969661729 0.6627791363391701 0.5074720177491066 1.0 0.5550087116644082 2 Q9H974 1 +PWWP domain [IPR000313] 0.5192152865481096 0.6584082474868005 0.5102758371878848 1.0 0.5575926808824906 6 Q7Z4V5,O96028 2 +Chromo shadow domain [IPR008251] 0.4878902830464123 0.6507632897579997 0.5151993009596247 1.0 0.5621075738476121 3 Q13185,P45973 2 +Chromo domain subgroup [IPR017984] 0.4878902830464123 0.6507632897579997 0.5151993009596247 1.0 0.5621075738476121 3 Q13185,P45973 2 +LEM domain [IPR003887] 0.5157826317534681 0.6435311418828799 0.5198795142860937 1.0 0.5669960908496567 6 P50402,Q86XL3 2 +Immunoglobulin subtype 2 [IPR003598] 0.5145866601431908 0.6383654118549573 0.5232358408097337 1.0 0.5702186446276454 6 P35613,P78310 2 +3'-5' exonuclease domain [IPR002562] 0.4340723453908996 0.6303008226443455 0.528497784869052 1.0 0.575290804533579 2 Q9NVH0 1 +WWE domain [IPR004170] 0.4826378756930422 0.6276674745469044 0.5302217966755711 1.0 0.576725355250334 3 Q7Z2W4,Q14669 2 +Matrin/U1-C-like, C2H2-type zinc finger [IPR003604] 0.449541882714755 0.6164561703454471 0.5375934908504605 1.0 0.5838491449389323 9 P43243,Q96KR1,Q969S3,Q14966 4 +Laminin, N-terminal [IPR008211] 0.4238623103850701 0.5816823169901822 0.5607806845398209 1.0 0.6064802528915046 2 P11047 1 +Laminin-type EGF domain [IPR002049] 0.4238623103850701 0.5816823169901822 0.5607806845398209 1.0 0.6064802528915046 2 P11047 1 +Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263] 0.4194865810968644 0.5611712143948046 0.5746808243327237 1.0 0.619860820776656 2 O00443 1 +Gamma tubulin complex component, C-terminal [IPR040457] 0.4171528588098178 0.5503174416946157 0.5821016632292555 1.0 0.6247803188099341 2 Q96CW5 1 +Gamma tubulin complex component protein, N-terminal [IPR041470] 0.4171528588098178 0.5503174416946157 0.5821016632292555 1.0 0.6247803188099341 2 Q96CW5 1 +Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378] 0.5003001919897407 0.5357991386486116 0.5920973775588836 1.0 0.6343102799951827 5 P36915,Q9NVN8 2 +4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896] 0.5070881195336141 0.5256407621813299 0.5991378294606593 1.0 0.6411271423015344 4 P21912,Q16134 2 +Guanine nucleotide exchange factor, N-terminal [IPR032691] 0.409276546091016 0.5141508549665171 0.6071465244414536 1.0 0.6489635413676056 2 Q92538 1 +HECT domain [IPR000569] 0.4062520109544171 0.5025625076679734 0.6152718946412228 1.0 0.6574011214375745 12 P46934 1 +Dehydrogenase, E1 component [IPR001017] 0.402567094515753 0.4839454888015619 0.6284245559808233 1.0 0.6699420942137906 2 Q02218 1 +L27 domain [IPR004172] 0.4850464070679298 0.4759318733309287 0.6341229138944651 1.0 0.6752564962355758 5 Q9NZW5,Q14168 2 +Zinc finger, double-stranded RNA binding [IPR022755] 0.484893652423196 0.4753429712578402 0.6345425353748111 1.0 0.6754500751366055 5 Q14966,Q969S3 2 +tRNA synthetases class I, catalytic domain [IPR032678] 0.3973162193698953 0.4607224503842885 0.6449977458448326 1.0 0.6855514963320826 2 Q9HA77 1 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.48807897363281 0.4542643530964678 0.649638569692651 1.0 0.6899772240200353 4 P14866,Q9UKA9 2 +SAP domain [IPR003034] 0.3969706145466631 0.4542518477530715 0.6496475693766106 1.0 0.6899772240200353 12 Q9BUJ2,Q1KMD3 2 +Matrin/U1-C, C2H2-type zinc finger [IPR000690] 0.4693341121495467 0.4510369049741586 0.651962950714065 1.0 0.6921774878609138 6 P43243,Q12874,Q14966,Q15428,P09234 5 +Ras-associating (RA) domain [IPR000159] 0.4772220935684048 0.4150089013760477 0.6781353868663635 1.0 0.7183530394257637 4 Q96L92 1 +TGS [IPR004095] 0.4306468070842652 0.3887011229172073 0.6974972515971967 1.0 0.7369390604672763 7 Q9NTK5 1 +EGF-like domain [IPR000742] 0.4238348503048287 0.3616304513518663 0.7176282057675829 1.0 0.755958495689887 7 Q08431 1 +BRK domain [IPR006576] 0.4158155821418303 0.3566572161598523 0.7213484383016016 1.0 0.7593141455806333 3 P51532,Q9P2D1 2 +Morc, S5 domain 2-like [IPR041006] 0.3719369894982506 0.3543205853782238 0.7230986422519887 1.0 0.7605926459243141 2 Q14149 1 +Major sperm protein (MSP) domain [IPR000535] 0.4128975780566182 0.3460491317292284 0.7293057912749696 1.0 0.7662702357458061 3 Q9P0L0,Q8NHP6 2 +Bromo adjacent homology (BAH) domain [IPR001025] 0.4556333917104558 0.340706066750633 0.7333248710494695 1.0 0.7698301513068215 4 Q86U86,Q13330,O94776 3 +DNA mismatch repair protein MutS-like, N-terminal [IPR007695] 0.4111467756054972 0.3397440133503705 0.7340493132883354 1.0 0.7698301513068215 3 P52701,P20585 2 +DNA mismatch repair protein MutS, C-terminal [IPR000432] 0.4111467756054972 0.3397440133503705 0.7340493132883354 1.0 0.7698301513068215 3 P52701,P20585 2 +DNA mismatch repair protein MutS, connector domain [IPR007860] 0.4111467756054972 0.3397440133503705 0.7340493132883354 1.0 0.7698301513068215 3 P52701,P20585 2 +DNA mismatch repair protein MutS, core [IPR007696] 0.4111467756054972 0.3397440133503705 0.7340493132883354 1.0 0.7698301513068215 3 P52701,P20585 2 +DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133] 0.406298385559022 0.3225228958738723 0.7470565952820782 1.0 0.7811637446984913 3 Q07864 1 +DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134] 0.406298385559022 0.3225228958738723 0.7470565952820782 1.0 0.7811637446984913 3 Q07864 1 +Linker histone H1/H5, domain H15 [IPR005818] 0.4075372480280462 0.2996319264939905 0.7644579286180067 1.0 0.7970086416772083 7 P10412,P16402,Q149N8,P07305,P16403,Q5SSJ5 6 +Poly(ADP-ribose) polymerase, catalytic domain [IPR012317] 0.3994747592646795 0.2989004008168205 0.7650160412718556 1.0 0.7970086416772083 3 Q7Z2W4,Q9UGN5 2 +DnaJ domain [IPR001623] 0.3192179233082638 0.2959903871258715 0.767237422618281 1.0 0.7990298057337433 19 Q96KC8,Q9UBS4,Q9Y2G8,Q9UGP8,Q9NVH1 5 +Myotubularin-like phosphatase domain [IPR010569] 0.3491831971995313 0.2685685649863399 0.7882617052663854 1.0 0.8167323031581666 2 Q9Y217 1 +S100/CaBP-9k-type, calcium binding, subdomain [IPR013787] 0.3892617449664565 0.2649525581613411 0.79104600910146 1.0 0.8193182588797032 3 P60903,Q99584 2 +Dynein heavy chain, tail [IPR013594] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.862452800382265 2 Q8NCM8 1 +Dynein heavy chain, linker [IPR013602] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.862452800382265 2 Q8NCM8 1 +Dynein heavy chain region D6 P-loop domain [IPR004273] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.862452800382265 2 Q8NCM8 1 +Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.862452800382265 2 Q8NCM8 1 +Dynein heavy chain, coiled coil stalk [IPR024743] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.862452800382265 2 Q8NCM8 1 +Dynein heavy chain, ATP-binding dynein motor region [IPR035706] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.862452800382265 2 Q8NCM8 1 +Dynein heavy chain AAA lid domain [IPR041658] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.862452800382265 2 Q8NCM8 1 +Dynein heavy chain, C-terminal domain [IPR041228] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.862452800382265 2 Q8NCM8 1 +Dynein heavy chain, AAA module D4 [IPR024317] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.862452800382265 2 Q8NCM8 1 +Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598] 0.3656259118762855 0.1933833075025543 0.8466587873730675 1.0 0.8671153826684139 3 Q9UNQ2,Q9H5Q4 2 +Post-SET domain [IPR003616] 0.3924581820234275 0.1711952531499972 0.8640702398354541 1.0 0.8824018270883458 5 O96028 1 +Cyclic nucleotide-binding domain [IPR000595] 0.383410750521617 0.1483238243902465 0.882087214167407 1.0 0.8991843819940545 5 Q8IY17,Q9Y4G8,Q6P4Q7 3 +Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.3383190147108065 0.1429810726390637 0.886305129440168 1.0 0.902512214991064 9 O15254,Q15067 2 +SCP2 sterol-binding domain [IPR003033] 0.336154070615709 0.1190982918785653 0.9051974839961204 1.0 0.91944236571852 3 P51659,Q6YN16 2 +Beta-Casp domain [IPR022712] 0.3619381202568661 0.0934924149567309 0.9255123752906924 1.0 0.938733980651988 4 Q9P2I0,Q5TA45,Q9NV88 3 +Zinc finger, CCHC-type [IPR001878] 0.30378088397173 0.0489951579773916 0.9609231546814938 1.0 0.971182120745709 9 Q9BWF3 1 +Immunoglobulin I-set [IPR013098] 0.3333333333333394 0.0465732141157242 0.9628533808960182 1.0 0.972711414491907 4 P10586,O75962,P13591 3 +Spen paralogue and orthologue SPOC, C-terminal [IPR012921] 0.3316788321167916 0.045525458330162 0.9636884831186818 1.0 0.972711414491907 5 Q92576,Q8NDT2,Q96T37,Q9BTC0 4 +Histone deacetylase domain [IPR023801] 0.2935665431597365 0.0426507271847397 0.9659799578069131 1.0 0.9745588206648788 3 Q9UBN7 1 +Mu homology domain [IPR028565] 0.3266199649737378 0.037520983222465 0.9700696097332376 1.0 0.9779899508847693 4 Q96CW1,Q9Y2T2,Q9BXS5 3 +EH domain [IPR000261] 0.3215734127786829 0.0324523725927019 0.9741112971691546 1.0 0.9817161405111424 6 Q96D71 1 +SPRY-associated [IPR006574] 0.319030939871577 0.0281475573120596 0.9775444638328874 1.0 0.9848266325950338 4 Q14258,P14373,Q12899 3 +Proteasome activator PA28, C-terminal domain [IPR003186] 0.2646134551763458 0.0102923383576813 0.9917880471151816 1.0 0.9984679382513704 3 Q9UL46 1 +Proteasome activator PA28, N-terminal domain [IPR003185] 0.2646134551763458 0.0102923383576813 0.9917880471151816 1.0 0.9984679382513704 3 Q9UL46 1 +Protein kinase, C-terminal [IPR017892] 0.2786746626084566 0.001570846698606 0.9987466461872484 1.0 1.0 8 Q15418 1 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b2d7b514f7c405e5c2668952dacdef5988d25178 --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2, SH3 domain [IPR035723]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-3' exoribonuclease 1, SH3-like domain [IPR041385]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "A-kinase anchor protein 10, PKA-binding (AKB) domain [IPR037719]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA lid domain [IPR041083]", "AAA+ ATPase domain [IPR003593]", "AAR2, C-terminal [IPR033648]", "AAR2, N-terminal [IPR033647]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC-type uncharacterised transport system [IPR019196]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALG11 mannosyltransferase, N-terminal [IPR031814]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARAP, RhoGAP domain [IPR037858]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ATM, catalytic domain [IPR044107]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "AWS domain [IPR006560]", "Abl Interactor 1, SH3 domain [IPR035725]", "Abl-interactor, homeo-domain homologous domain [IPR012849]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adaptor protein Cbl, EF hand-like [IPR014741]", "Adaptor protein Cbl, N-terminal helical [IPR003153]", "Adaptor protein Cbl, PTB domain [IPR024159]", "Adaptor protein Cbl, SH2-like domain [IPR014742]", "Adaptor protein ClpS, core [IPR003769]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha crystallin/Hsp20 domain [IPR002068]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin [IPR001599]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-2-macroglobulin, TED domain [IPR041813]", "Alpha-2-macroglobulin, bait region domain [IPR011625]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-amylase/branching enzyme, C-terminal all beta [IPR006048]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha-macroglobulin, receptor-binding [IPR009048]", "Alpha-macroglobulin-like, TED domain [IPR011626]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 1 [IPR041880]", "Ankyrin repeat and SAM domain-containing protein 1, SAM repeat 2 [IPR041882]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginine N-methyltransferase 2-like domain [IPR026480]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Argonaute hook domain [IPR019486]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Arrestin C-terminal-like domain [IPR011022]", "Arrestin-like, N-terminal [IPR011021]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Atg6, BARA domain [IPR040455]", "Atg6/beclin, coiled-coil domain [IPR041691]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BARD1, Zinc finger, RING-type [IPR039503]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Bcr-Abl oncoprotein oligomerisation [IPR015123]", "Beclin-1, BH3 domain [IPR029318]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brd8, Bromo domain [IPR037966]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBP/p300-type histone acetyltransferase domain [IPR031162]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not N-terminal domain [IPR007207]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHAT domain [IPR024983]", "CHCH [IPR010625]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CISK, PX domain [IPR037900]", "CLASP N-terminal domain [IPR024395]", "CLIP1, zinc knuckle [IPR032108]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "CNOT4, RNA recognition motif [IPR034261]", "COMM domain [IPR017920]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPPED1, metallophosphatase domain [IPR041867]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CREB-binding protein/p300, atypical RING domain [IPR010303]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CUT domain [IPR003350]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Calsyntenin, C-terminal [IPR045588]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cdc6, C-terminal [IPR015163]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centromere protein Cenp-F, N-terminal [IPR018463]", "Centromere protein Cenp-F, leucine-rich repeat-containing domain [IPR019513]", "Centrosomal CEP44 domain [IPR029157]", "Centrosomal protein of 290kDa, coiled-coil region [IPR032321]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Chaperone DnaJ, C-terminal [IPR002939]", "Checkpoint kinase 1, catalytic domain [IPR034670]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron Rho-interacting kinase, catalytic domain [IPR037708]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain [IPR041715]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class V myosin, motor domain [IPR036103]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Classical Protein Kinase C alpha, catalytic domain [IPR034663]", "Classical protein kinase C beta, catalytic domain [IPR034664]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coactivator CBP, KIX domain [IPR003101]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complement Clr-like EGF domain [IPR026823]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Copper homeostasis CutC domain [IPR023648]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin, C-terminal domain [IPR004367]", "Cyclin, N-terminal [IPR006671]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "Cytosolic aminopeptidase 1/4 [IPR033852]", "Cytosolic carboxypeptidase, N-terminal [IPR040626]", "Cytosolic fatty-acid binding [IPR000463]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDB1- and CUL4-associated factor 15, WD40 repeat-containing domain [IPR032734]", "DDE superfamily endonuclease domain [IPR004875]", "DDH domain [IPR001667]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DExH-box ATP-dependent RNA helicase, R3H domain [IPR034083]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHHA2 domain [IPR004097]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIRP domain [IPR033471]", "DJ-1/PfpI [IPR002818]", "DM10 domain [IPR006602]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase III subunit RPC5, C-terminal [IPR045576]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding domain, Est1-type [IPR018834]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DUS-like, FMN-binding domain [IPR035587]", "DUS2, double-stranded RNA binding domain [IPR044463]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dehydrogenase, E1 component [IPR001017]", "Deoxycytidylate deaminase domain [IPR035105]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "DhaK domain [IPR004006]", "DhaL domain [IPR004007]", "Diacylglycerol kinase, accessory domain [IPR000756]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dienelactone hydrolase [IPR002925]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DM14 [IPR006608]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3498 [IPR021887]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4592 [IPR028030]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5050 [IPR032485]", "Domain of unknown function DUF5595 [IPR040967]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E1A-binding protein p400, N-terminal [IPR031575]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase CBL-B, RING finger, HC subclass [IPR039520]", "E3 ubiquitin-protein ligase SH3RF1, second SH3 domain [IPR035795]", "E3 ubiquitin-protein ligase UBR-like, C-terminal [IPR044046]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELK domain [IPR005539]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXOG, C-terminal [IPR041003]", "EXPERA domain [IPR033118]", "EYA domain [IPR006545]", "EYA domain, metazoan [IPR042577]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "EngB-type guanine nucleotide-binding (G) domain [IPR030393]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Ets domain [IPR000418]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease Xrn1, D2/D3 domain [IPR041106]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "F-box/LRR-repeat protein 18, LRR domain [IPR045627]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain [IPR002938]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM20, C-terminal [IPR009581]", "FAM69, protein-kinase domain [IPR022049]", "FAM83, N-terminal [IPR012461]", "FAM91, C-terminal domain [IPR028097]", "FAM91, N-terminal domain [IPR028091]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FARP1/FARP2/FRMD7, FERM domain C-lobe [IPR041788]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FCP1-like phosphatase, C-terminal [IPR015388]", "FCP1-like phosphatase, phosphatase domain [IPR011947]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FIST, C-domain [IPR019494]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FLYWCH-type zinc finger-containing protein, N-terminal [IPR029279]", "FMP27, C-terminal [IPR019443]", "FMP27, GFWDK domain [IPR019441]", "FMP27, N-terminal [IPR019439]", "FY-rich, C-terminal [IPR003889]", "FY-rich, N-terminal [IPR003888]", "FYVE zinc finger [IPR000306]", "Fanconi anaemia group A protein, N-terminal domain [IPR031729]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "FeS cluster biogenesis [IPR000361]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "Fibronectin type III and SPRY containing 1, PRY/SPRY domain [IPR035742]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Focadhesin/RST, DUF3730 [IPR022542]", "Folliculin, DENN domain [IPR032035]", "Folliculin/SMCR8, longin domain [IPR037520]", "Folliculin/SMCR8, tripartite DENN domain [IPR037521]", "Follistatin-like, N-terminal [IPR003645]", "Fork head domain [IPR001766]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Freud, C2 domain [IPR037772]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G2 and S phase-expressed protein 1, N-terminal [IPR032768]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPR domain [IPR000965]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP-binding protein, middle domain [IPR032305]", "GTP1/OBG domain [IPR006169]", "GTPase HflX, N-terminal [IPR025121]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galactosyltransferase, C-terminal [IPR027791]", "Galactosyltransferase, N-terminal [IPR027995]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-butyrobetaine hydroxylase-like, N-terminal [IPR010376]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gelsolin-like domain [IPR007123]", "Germinal-centre associated nuclear protein, CID domain [IPR031910]", "Germinal-centre associated nuclear protein, MCM3AP domain [IPR031907]", "Germinal-centre associated nuclear protein, nucleoporin homology domain [IPR031908]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, C-terminal [IPR006096]", "Glutamate/phenylalanine/leucine/valine dehydrogenase, dimerisation domain [IPR006097]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, C-terminal [IPR006109]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, N-terminal [IPR011128]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 13, N-terminal [IPR004193]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycosyltransferase subfamily 4-like, N-terminal domain [IPR028098]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HCLS1-binding protein 3, PX domain [IPR037901]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HEPN domain [IPR007842]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Heat shock protein beta-1, ACD domain [IPR037876]", "Helical and beta-bridge domain [IPR010643]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Heparinase II, N-terminal [IPR032518]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HflX-type guanine nucleotide-binding (G) domain [IPR030394]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histidyl-anticodon-binding [IPR033656]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxyacylglutathione hydrolase, C-terminal domain [IPR032282]", "Hydroxyacylglutathione hydrolase, MBL domain [IPR035680]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "INTS6/SAGE1/DDX26B/CT45, C-terminal [IPR029307]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISG20, DEDDh 3'-5' exonuclease domain [IPR037433]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Int12, PHD finger [IPR039054]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Interleukin-1 receptor-associated kinase 1, death domain [IPR035533]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intimal thickness related receptor, IRP [IPR019336]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "JmjN domain [IPR003349]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KMT2A, PHD domain 1 [IPR042023]", "KMT2A, PHD domain 2 [IPR042025]", "KMT2A, PHD domain 3 [IPR044133]", "KMT2A, ePHD domain [IPR041958]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Katanin p80 subunit, C-terminal [IPR028021]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated [IPR032405]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like KIF1-type [IPR022140]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kinetochore protein Cenp-F/LEK1, Rb protein-binding domain [IPR018302]", "Kinetochore protein Nuf2, N-terminal [IPR005549]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-2 [IPR015132]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIN-9, C-terminal [IPR045831]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Lasp1, SH3 domain [IPR035630]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Linker histone H1/H5, domain H15 [IPR005818]", "Lipocalin/cytosolic fatty-acid binding domain [IPR000566]", "Liprin-alpha, SAM domain repeat 1 [IPR037620]", "Liprin-alpha, SAM domain repeat 2 [IPR037621]", "Liprin-alpha, SAM domain repeat 3 [IPR037622]", "Liprin-beta, SAM domain repeat 1 [IPR037617]", "Liprin-beta, SAM domain repeat 2 [IPR037618]", "Liprin-beta, SAM domain repeat 3 [IPR037619]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "Lunapark domain [IPR019273]", "Lysine-specific demethylase-like domain [IPR013637]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MAGE homology domain [IPR002190]", "MAM domain [IPR000998]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MCM3AP, RNA recognition motif [IPR034265]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MTMR6, PH-GRAM domain [IPR035998]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Macroglobulin domain MG3 [IPR041555]", "Macroglobulin domain [IPR002890]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Microspherule protein, N-terminal domain [IPR025999]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MnmG, N-terminal domain [IPR040131]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdenum cofactor synthesis C-terminal [IPR010505]", "Molybdopterin cofactor biosynthesis C (MoaC) domain [IPR002820]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Morc, S5 domain 2-like [IPR041006]", "Mot1, ATP-binding domain [IPR044078]", "Mot1, central domain [IPR022707]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Mvd1, C-terminal [IPR041431]", "Myb domain [IPR017930]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin 5a, cargo-binding domain [IPR037988]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myotubularin-like phosphatase domain [IPR010569]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-CoR, GPS2-interacting domain [IPR031557]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-end aminoacyl transferase, N-terminal [IPR007471]", "N-end rule aminoacyl transferase, C-terminal [IPR007472]", "N-terminal extension of GAT domain [IPR041198]", "NAD(P) binding domain of glutamate dehydrogenase [IPR033922]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NCBP2, RNA recognition motif [IPR034148]", "NDPK7, first NDPk domain [IPR035525]", "NDPK7, second NDPk domain [IPR037993]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NFkappaB IPT domain [IPR033926]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NOT4, modified RING finger, HC subclass (C4C4-type) [IPR039515]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Net1, PH domain [IPR037853]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Neuropilin, C-terminal [IPR022579]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Notch domain [IPR000800]", "Notch, C-terminal [IPR024600]", "Notch, NOD domain [IPR010660]", "Notch, NODP domain [IPR011656]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear receptor coactivator, CREB-bp-like, interlocking [IPR014744]", "Nuclear speckle splicing regulatory protein 1, N-terminal [IPR018612]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar pre-ribosomal-associated protein 1, C-terminal domain [IPR032436]", "Nucleolar pre-ribosomal-associated protein 1, N-terminal [IPR021714]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Opioid growth factor receptor (OGFr) conserved domain [IPR006757]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "Oxoglutarate/iron-dependent oxygenase, C-terminal degradation domain [IPR019601]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PCNA-associated factor, histone-like domain [IPR031444]", "PD-(D/E)XK endonuclease-like domain, AddAB-type [IPR038726]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHLDB1/2/3, PH domain [IPR037810]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K p85 subunit, C-terminal SH2 domain [IPR035020]", "PI3K p85 subunit, N-terminal SH2 domain [IPR035022]", "PI3K regulatory subunit p85-related , inter-SH2 domain [IPR032498]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIH1, N-terminal [IPR012981]", "PIH1D1/2/3, CS-like domain [IPR041442]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PKHA4-7, PH domain [IPR040392]", "PLAA family ubiquitin binding domain [IPR015155]", "PLAT/LH2 domain [IPR001024]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "POU domain [IPR013847]", "POU domain, class 2, transcription factor 1, C-terminal [IPR045703]", "POU-specific domain [IPR000327]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PTBP2, RNA recognition motif 1 [IPR035002]", "PTBP2, RNA recognition motif 3 [IPR034799]", "PTBP2, RNA recognition motif 4 [IPR034800]", "PUA domain [IPR002478]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Par3/HAL, N-terminal [IPR021922]", "Patatin-like phospholipase domain [IPR002641]", "Patatin-like phospholipase domain containing protein 8-like [IPR045217]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C14, p20 domain [IPR001309]", "Peptidase C14, caspase non-catalytic subunit p10 [IPR002138]", "Peptidase C14A, caspase catalytic domain [IPR015917]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentrin/AKAP-450 centrosomal targeting domain [IPR019528]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "Persulfide dioxygenase-like, MBL-fold metallo-hydrolase domain [IPR044528]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 3-kinase regulatory subunit beta, SH3 domain [IPR035586]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Phox-associated domain [IPR003114]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plus-3 domain [IPR004343]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-mRNA-splicing factor 38, C-terminal [IPR024767]", "Pre-mRNA-splicing factor SLU7 domain [IPR021715]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Prokaryote proline-tRNA ligase core domain [IPR033730]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 3,4-dihydroxylase TPA1/OFD1, N-terminal domain [IPR039558]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein NPAT, C-terminal domain [IPR031442]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein Smaug, SAM domain [IPR037634]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein furry, C-terminal [IPR045842]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Proto-oncogene c-Rel, RHD, N-terminal subdomain [IPR042845]", "Prp18 [IPR004098]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, RsuA/RluA-like [IPR006145]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "Pumilio, RNA binding domain [IPR033712]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative RNA-binding protein 47, RNA recognition motif 2 [IPR034440]", "Putative RNA-binding protein 47, RNA recognition motif 3 [IPR034445]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine 5'-phosphate oxidase, putative [IPR011576]", "Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal [IPR019576]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM15B, RNA recognition motif 1 [IPR034475]", "RBM15B, RNA recognition motif 2 [IPR034535]", "RBM15B, RNA recognition motif 3 [IPR034536]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM7, RNA recognition motif [IPR034500]", "RBM8, RNA recognition motif [IPR033744]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RGS domain [IPR016137]", "RGS10, RGS domain [IPR037879]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIO kinase [IPR000687]", "RIO2 kinase winged helix domain, N-terminal [IPR015285]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RUN domain [IPR004012]", "RWD domain [IPR006575]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raf-like Ras-binding [IPR003116]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap/Ran-GAP domain [IPR000331]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Regulator of MON1-CCZ1 complex, C-terminal [IPR009755]", "Rel homology dimerisation domain [IPR032397]", "Rel homology domain (RHD), DNA-binding domain [IPR011539]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor Mcm10, C-terminal [IPR015411]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Replication termination factor 2, RING-finger [IPR027799]", "Reticulon [IPR003388]", "Retinoblastoma-associated protein, A-box [IPR002720]", "Retinoblastoma-associated protein, B-box [IPR002719]", "Retinoblastoma-associated protein, C-terminal [IPR015030]", "Retinoblastoma-associated protein, N-terminal [IPR024599]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Rhs repeat-associated core [IPR022385]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease H2 subunit B, wHTH domain [IPR019024]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Rnh202, triple barrel domain [IPR041195]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "Rubisco LSMT, substrate-binding domain [IPR015353]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SATB, CUT1-like DNA-binding domain [IPR032355]", "SATB, ubiquitin-like oligomerisation domain [IPR032392]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SEPARIN core domain [IPR030397]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SETD2/Set2, SET domain [IPR044437]", "SETD3, SET domain [IPR044428]", "SETD7, SET domain [IPR044436]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SH3RF1/SH3RF3, fourth SH3 domain [IPR035816]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMYD3, SET domain [IPR044420]", "SMYD4, SET domain [IPR044421]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX14, RGS domain [IPR037892]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX8/Mvp1, PX domain [IPR035704]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRA1/Sec31 [IPR009917]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SREK1, RNA recognition motif 2 [IPR034192]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Sas10 C-terminal domain [IPR018972]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Scm-like with four MBT domains protein 1/2, SAM domain [IPR037604]", "Sde2, N-terminal ubiquitin domain [IPR024974]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase Rio2 [IPR030484]", "Serine/threonine-protein kinase Sgk3, catalytic domain [IPR037709]", "Serine/threonine-protein kinase greatwall, catalytic domain [IPR037638]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Set2 Rpb1 interacting domain [IPR013257]", "Siah interacting protein, N-terminal [IPR015120]", "Sialidase [IPR011040]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Signal transduction histidine kinase-related protein, C-terminal [IPR004358]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin 4, PX domain [IPR034902]", "Sorting nexin 8/Mvp1, BAR domain [IPR045734]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, C-terminal [IPR013937]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-14, PX domain [IPR037436]", "Sorting nexin-4, BAR domain [IPR037430]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen 2, first double-stranded RNA binding domain [IPR044476]", "Staufen 2, fourth double-stranded RNA binding domain [IPR044474]", "Staufen 2, second double-stranded RNA binding domain [IPR044464]", "Staufen 2, third double-stranded RNA binding domain [IPR044473]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Strawberry notch, AAA domain [IPR039187]", "Strawberry notch, helicase C domain [IPR026937]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulfotransferase domain [IPR000863]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Synembryn [IPR008376]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "Syntrophin, split Pleckstrin homology (PH) domain [IPR041428]", "TAF6, C-terminal HEAT repeat domain [IPR011442]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFA2, Winged helix domain 2 [IPR040501]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TFIIH p62 subunit, N-terminal [IPR013876]", "TGS [IPR004095]", "THADA/TRM732, DUF2428 [IPR019442]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIA-1, RNA recognition motif 2 [IPR034830]", "TIA-1, RNA recognition motif 3 [IPR034832]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TNF receptor-associated factor 2, MATH domain [IPR037305]", "TNF receptor-associated factor, BIRC3 binding domain [IPR032070]", "TNRC6, PABC binding domain [IPR032226]", "TNRC6A, RNA recognition motif [IPR034924]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM27, PRY/SPRY domain [IPR035791]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TSG101 and ALIX binding domain of CEP55 [IPR022008]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "TauD/TfdA-like domain [IPR003819]", "Telomerase activating protein Est1, N-terminal [IPR019458]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere repeat-binding factor, dimerisation domain [IPR013867]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Telomere-length maintenance and DNA damage repair [IPR021668]", "Telomeric repeat-binding factor 2, Rap1-binding domain [IPR031902]", "Teneurin intracellular, N-terminal [IPR009471]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tex protein, YqgF-like domain [IPR032639]", "Tex, S1 domain [IPR044146]", "Tex-like protein, N-terminal [IPR018974]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine synthase, N-terminal [IPR029144]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "TopBP1, first BRCT domain [IPR044737]", "Topoisomerase I C-terminal domain [IPR025834]", "Tox-GHH domain [IPR028916]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor 20, ePHD domain [IPR041972]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor Elf, N-terminal [IPR022084]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE beta subunit, DNA-binding domain [IPR003166]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "Trm3/ TARBP1, C-terminal [IPR044748]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin binding cofactor C-like domain [IPR012945]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase Yes, SH3 domain [IPR035751]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UDP-N-acetylglucosamine 2-epimerase domain [IPR003331]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UME domain [IPR012993]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain [IPR032353]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Unconventional myosin-Ie/If, SH3 domain [IPR035507]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Upstream-binding protein 1, SAM domain [IPR037600]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar protein sorting-associated, VPS28, C-terminal [IPR017899]", "Vacuolar protein sorting-associated, VPS28, N-terminal [IPR017898]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vps72/YL1, C-terminal [IPR013272]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, D1 domain [IPR040992]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "Yippee domain [IPR034751]", "Yippee/Mis18/Cereblon [IPR004910]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "YrdC-like domain [IPR006070]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, C5HC2-type [IPR004198]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FCS-type [IPR012313]", "Zinc finger, FLYWCH-type [IPR007588]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, Mcm10/DnaG-type [IPR015408]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TAZ-type [IPR000197]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, TRAF-type [IPR001293]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc-finger CCCH domain [IPR041686]", "Zinc-finger domain of monoamine-oxidase A repressor R1 [IPR018866]", "Zinc-ribbon domain [IPR026870]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "hnRPLL, RNA recognition motif 1 [IPR034985]", "hnRPLL, RNA recognition motif 2 [IPR034986]", "hnRPLL, RNA recognition motif 3 [IPR034983]", "hnRPLL, RNA recognition motif 4 [IPR034987]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG, C-terminal [IPR026904]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN2", "ACTN4", "ACY1", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT4", "AGPAT5", "AGPS", "AGTPBP1", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK4", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "APIP", "APMAP", "APP", "APRT", "AQR", "ARAP1", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL8A", "ARL8B", "ARMC10", "ARMC9", "ARMCX3", "ARMT1", "ARRB2", "ARSA", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG7", "ATIC", "ATL2", "ATL3", "ATM", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GALT3", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAP18", "BARD1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCKDHB", "BCKDK", "BCR", "BCS1L", "BECN1", "BEND3", "BIRC6", "BLM", "BLVRA", "BMS1", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD8", "BRIX1", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "C1orf35", "C2CD2L", "C2CD5", "C3orf58", "CACYBP", "CAD", "CALCOCO1", "CALM3", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CBL", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC93", "CCNB1", "CCNB2", "CD109", "CD2AP", "CD2BP2", "CDC23", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPV", "CEP170", "CEP290", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHRAC1", "CHTF18", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLPB", "CLPX", "CLSTN3", "CLTC", "CLUH", "CMBL", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT3", "CNOT4", "CNPY2", "COA3", "COASY", "COIL", "COMMD2", "COMMD7", "COMMD8", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREBBP", "CRK", "CRKL", "CROT", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTC", "CWC22", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF15", "DCP1A", "DCP1B", "DCTD", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND5B", "DENR", "DFFA", "DGKE", "DHCR24", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2A", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DR1", "DRG1", "DRG2", "DSC2", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC2H1", "EARS2", "ECE1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP3", "EMC1", "EMC7", "EMD", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERLIN1", "ERLIN2", "ERP29", "ERP44", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETHE1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC4", "EXOC8", "EXOG", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EYA4", "EZR", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM129B", "FAM208A", "FAM20B", "FAM49B", "FAM83D", "FAM8A1", "FAM91A1", "FANCA", "FANCI", "FAR1", "FAR2", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBXL18", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNDC3A", "FOCAD", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FSD1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYCO1", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GALE", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP1", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNB1", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGB1", "GORASP2", "GOT1", "GOT2", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR180", "GPR89B", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP6", "GTPBP8", "GTSE1", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDDC2", "HDGF", "HDGFL2", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMG20A", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HP1BP3", "HPRT1", "HS1BP3", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90AB4P", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPB1", "HSPBP1", "HSPH1", "HTATSF1", "HUWE1", "IAH1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS14", "INTS3", "INTS6", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISG20L2", "ISOC1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPK1", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KATNB1", "KCTD10", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA1211", "KIAA1468", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LSM12", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD1", "MBD3", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MEPCE", "METAP2", "METTL13", "METTL25", "METTL7B", "MFAP1", "MFGE8", "MFN1", "MFSD10", "MGME1", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU2", "MID1", "MIEF1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPDZ", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL2", "MRPL24", "MRPL39", "MRPL44", "MRPL45", "MRPL46", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA40", "NAA50", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCBP2", "NCKIPSD", "NCL", "NCLN", "NCOR1", "NCSTN", "NDC80", "NDUFA10", "NDUFA2", "NDUFA8", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFE", "NEMF", "NENF", "NES", "NET1", "NEU1", "NF1", "NFATC2IP", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP50", "NUP54", "NUP62", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL8", "OSBPL9", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "OXSM", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PARS2", "PATL1", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHLDB2", "PI4K2A", "PI4KA", "PICALM", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLEKHA7", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "POP1", "POR", "POU2F1", "PPAN", "PPAT", "PPFIA1", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF18", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRUNE1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB36", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAF1", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RASAL2", "RAVER1", "RB1", "RBBP4", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REL", "RELA", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RGS10", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOK1", "RIOK2", "RIOX2", "RIPK1", "RMC1", "RMND1", "RNASEH2A", "RNASEH2B", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRP12", "RRP7A", "RSF1", "RTF1", "RTFDC1", "RTN3", "RTN4", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF11", "SCCPDH", "SCML2", "SCO2", "SCP2", "SCRIB", "SCYL1", "SCYL2", "SDAD1", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SETD1A", "SETD2", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFMBT1", "SFPQ", "SFSWAP", "SGK3", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SIN3A", "SIPA1", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC27A2", "SLC27A4", "SLC2A1", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD3", "SMYD4", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX14", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRA1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STOML2", "STRBP", "STRIP1", "STRN", "STUB1", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TAOK1", "TAP1", "TAP2", "TAPBP", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TDP2", "TDRKH", "TECR", "TELO2", "TENM3", "TERF2", "TERF2IP", "TES", "TEX10", "TFAM", "TFB1M", "TFB2M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THNSL1", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TKFC", "TKT", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM201", "TMEM205", "TMEM97", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TNRC6A", "TOE1", "TOM1", "TOM1L2", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSR1", "TST", "TSTA3", "TTC28", "TTC4", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR2", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UGDH", "UGGT1", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP32", "USP34", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTP3", "UTRN", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VCP", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS28", "VPS29", "VPS37B", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "WAPL", "WARS", "WASF2", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR3", "WDR35", "WDR36", "WDR43", "WDR46", "WDR47", "WDR62", "WFS1", "WNK1", "WWP2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO6", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YBX1", "YES1", "YKT6", "YME1L1", "YPEL5", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZYX"], "leading_proteins": ["ABCB1", "ABCB8", "ABCD4", "ABI1", "ACOX1", "ACOX3", "AFG3L2", "AGPAT1", "AGPAT5", "AKAP10", "AKAP8L", "ANKLE2", "AP1M1", "AP2M1", "AP3M1", "ATAD3B", "ATM", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATR", "BCKDK", "BSG", "BUB1", "CALU", "CAMK2G", "CARS2", "CBX3", "CBX5", "CCNB2", "CDKAL1", "CELF1", "CERS2", "CETN2", "CHD7", "CIRBP", "CLCN7", "CNNM3", "CNNM4", "CNOT4", "COPB2", "CPSF2", "CSTF3", "CTPS1", "CXADR", "CYB5B", "CYB5D2", "CYFIP1", "DAZAP1", "DCUN1D4", "DDX21", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIDO1", "DIMT1", "DNAJB11", "DNAJC1", "DNAJC11", "DNAJC16", "DPM1", "DYNC2H1", "EFCAB14", "EHD4", "EIF4B", "ELMOD2", "EMD", "ERAP1", "ERAP2", "ERLIN1", "ETFDH", "EWSR1", "EXD2", "EXOC2", "FAR2", "FCGRT", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "FMR1", "FOXRED1", "FUBP1", "FUS", "FXR1", "FXR2", "GALNT1", "GALNT4", "GBF1", "GDAP1", "GLO1", "GM2A", "GNL1", "GNL3L", "GNPAT", "GPD2", "GSTA4", "GTPBP8", "H1F0", "HADH", "HDAC6", "HDGFL2", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HLA-A", "HLA-B", "HLA-C", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPR", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB4P", "HSP90B1", "IDH1", "INTS11", "INTS9", "ITCH", "ITM2B", "KCTD12", "KHDRBS1", "KHSRP", "KPNA1", "L2HGDH", "LAMC1", "LBR", "LCLAT1", "LETM1", "LGALS3BP", "LMAN1", "LMNB2", "LNPEP", "LPCAT1", "MAN2A1", "MATR3", "MFGE8", "MFSD10", "MICU2", "MIPEP", "MKI67", "MORC3", "MOSPD2", "MPP2", "MPP6", "MRPL2", "MRPL45", "MRPS5", "MSH3", "MSH6", "MSI2", "MSMO1", "MTA1", "MTA2", "MTMR6", "MTOR", "MYO1D", "NCAM1", "NCLN", "NEDD4", "NEDD4L", "NEFM", "NOL8", "NRDC", "NSD2", "NUCB1", "NUCB2", "NUP155", "OGDH", "OLA1", "OPA1", "OS9", "OXSM", "P3H1", "P4HA1", "PABPC1", "PARP2", "PBRM1", "PDK1", "PDK3", "PGRMC2", "PHB2", "PHF3", "PI4K2A", "PIK3C2A", "PITRM1", "PLD3", "PLOD3", "PMPCA", "PNPLA6", "PNPLA8", "POLE", "POR", "PRKDC", "PRPF40A", "PSME2", "PSPC1", "PTBP2", "PTCD1", "PTPRF", "PUF60", "PYCR2", "QTRT2", "RALY", "RAPGEF2", "RBM10", "RBM14", "RBM15", "RBM15B", "RBM27", "RBM3", "RBM4", "RBM47", "RBM5", "RBM6", "RBMX", "RCN2", "REPS1", "RPL27A", "RPS5", "RPS6KA1", "RTN3", "S100A10", "S100A13", "SDF4", "SDHB", "SEC63", "SF3A2", "SF3A3", "SF3B4", "SFPQ", "SHPRH", "SLC12A2", "SLC16A1", "SLC25A24", "SMARCA1", "SMARCA4", "SMN1*", "SMYD3", "SNRPC", "SNU13", "SNX27", "SPNS1", "SPTBN2", "SPTLC1", "STX12", "STX3", "STX5", "STX8", "SUN1", "SYNCRIP", "TAF15", "TAP1", "TAP2", "TBC1D9B", "TCERG1", "TDRKH", "TFB2M", "TIA1", "TIAL1", "TIMM13", "TIMM8B", "TJP1", "TMED10", "TMED2", "TMED7", "TMPO", "TPBG", "TRA2A", "TRA2B", "TRAM1", "TRIM25", "TRIM26", "TRIM27", "TRIO", "TRIP12", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBGCP3", "U2AF1", "U2AF2", "UQCRC1", "USP15", "USP32", "USP34", "USP4", "USP7", "VAMP7", "VAPA", "VIM", "XRN2", "YKT6", "YTHDC1", "YTHDC2", "ZC3HAV1", "ZFR", "ZNF326", "ZNF622", "ZNF638"]} \ No newline at end of file diff --git a/interpro_family/advanced/idx2term.json b/interpro_family/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6bc77b3f5c84d1db75e9b908ed2b0fcaab0b6f4d --- /dev/null +++ b/interpro_family/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]"} \ No newline at end of file diff --git a/interpro_family/advanced/plot_0.png b/interpro_family/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..683969a6cd165e7cdd762a8689b81790fe70b308 --- /dev/null +++ b/interpro_family/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ac015087d3b91ca666ee9d7d37f4fab9380fb93ae98284698df79c67902beaea +size 187386 diff --git a/interpro_family/basic/idx2term.json b/interpro_family/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6bc77b3f5c84d1db75e9b908ed2b0fcaab0b6f4d --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier protein [IPR002067]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..36e892ec68b2420c68467a833e6ca4c15f540be6 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1d3b9d5966a1eac89c251133957936fb389ff8e4cfa4daa0564ea5e33fe26e65 +size 136403 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..4917dbfa6c8d9f0dba32404baac93aceadba9622 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:baed0a1455365c4b50b7a41f407eae33a079bd0fc046e19752170d26dced148b +size 857818 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ed166cfdea0a7de1bb09f7ff101a1ed102ef88c6 --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier protein [IPR002067] 7 10 2.259449994193356 0.0238554075454122 5.686893203883495 11.07766990291262 0.8032246115450145 0.31892620527414 3.2338505495684404 1.5403272908315857 1.3918146051602212 0.3274613788058813 0.106411269870565 1.0 1.0 0.0846217526668656 0.0705348016344186 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a497dc3bc627b64d2725d904ac59182786143f7c --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 2616, + "title": "Average number of proteins per term", + "value": 1.2851681957186545 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b814e37d4931d7086c1387c86e0a77d9747c20f2 --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dbf41fdd6f8eb994a15a4de5d106703ae85ebdae --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,133 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Isocitrate dehydrogenase NADP-dependent [IPR004790] 0.9973745624270712 3.398325652841282 0.0006779966221959 0.8303878122125965 0.003424672227278 2 O75874 1 +Mitochondrial carrier UCP-like [IPR002030] 0.9859976662777118 3.3489366780910363 0.0008112233357748 0.8803304979159475 0.00376095630426 2 Q9UBX3 1 +Haem oxygenase [IPR002051] 0.9830805134189028 3.3362259427928493 0.0008492411343357 0.8916684324710542 0.0038366795360081 2 P30519 1 +Haem oxygenase-like [IPR016053] 0.9830805134189028 3.3362259427928493 0.0008492411343357 0.8916684324710542 0.0038366795360081 2 P30519 1 +Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678] 0.9775379229871628 3.3120224580012545 0.0009262411004609 0.9114483759951671 0.0040041174789479 2 O60830 1 +ER lumen protein retaining receptor [IPR000133] 0.9719953325554233 3.287749083624196 0.0010099180613525 0.9288724561803414 0.0041853137340301 2 P24390 1 +Tetraspanin, animals [IPR000301] 0.9635355892648756 3.2505646286781267 0.0011517608685061 0.9509415530565006 0.0044779918692968 2 O43657 1 +Tetraspanin/Peripherin [IPR018499] 0.9635355892648756 3.2505646286781267 0.0011517608685061 0.9509415530565006 0.0044779918692968 2 O43657 1 +Mpv17/PMP22 [IPR007248] 0.9562427071178536 3.218376616601632 0.0012891842195943 0.9657709876203868 0.0047904913614471 2 Q9NR77 1 +CD36 family [IPR002159] 0.950991831971992 3.195124795165955 0.0013977038910777 0.9742404807403052 0.0050433012124956 2 Q14108 1 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.9439906651108524 3.1640221800047086 0.001556049364956 0.982987305440158 0.005345372092155 2 Q9Y5L4 1 +ABC transporter Tap-like [IPR013305] 0.936697782963827 3.1315011215976045 0.0017391512175843 0.9894705629563876 0.0057372252020186 2 Q03519 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.9361143523920664 3.1288940120442157 0.0017546558705658 0.9898898111572126 0.005759322154831 2 Q9Y487 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.9361143523920664 3.1288940120442157 0.0017546558705658 0.9898898111572126 0.005759322154831 2 Q9Y487 1 +Integral membrane protein 2 [IPR040145] 0.9346557759626613 3.122372712007183 0.0017939966355042 0.990880223105808 0.0058299319235766 2 Q9Y287 1 +Purine 5'-nucleotidase [IPR016695] 0.9296966161026852 3.100162532620066 0.0019341447646026 0.9936837028770036 0.0061273657680309 2 P49902 1 +Nucleobindin [IPR040250] 0.9285297549591522 3.0949281080377165 0.0019686060714341 0.994229226669939 0.0061972003403991 2 P80303 1 +Nonaspanin (TM9SF) [IPR004240] 0.928238039673274 3.0936189949691415 0.001977312398357 0.9943594288852962 0.0062022173070768 2 Q9HD45 1 +Membrane bound O-acyl transferase, MBOAT [IPR004299] 0.9267794632438754 3.087070385455712 0.0020213972750329 0.9949749859756728 0.0062790781747022 2 Q96N66 1 +Cleft lip and palate transmembrane 1 [IPR008429] 0.91219369894982 3.0213039048811794 0.0025168860669295 0.9986293547822944 0.007414610305279 2 O96005 1 +Cleft lip and palate transmembrane protein 1-like protein [IPR030434] 0.91219369894982 3.0213039048811794 0.0025168860669295 0.9986293547822944 0.007414610305279 2 O96005 1 +Peroxisomal acyl-coenzyme A oxidase [IPR034171] 0.9072345390898484 2.998826469486689 0.0027102162113339 0.9991745242069476 0.0077103527332979 2 O15254 1 +Acyl-CoA oxidase [IPR012258] 0.9072345390898484 2.998826469486689 0.0027102162113339 0.9991745242069476 0.0077103527332979 2 O15254 1 +Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554] 0.889731621936992 2.9190155845594377 0.0035113866842546 0.999899157719904 0.0091799332652105 2 Q14738 1 +Cytochrome P450 [IPR001128] 0.8885647607934638 2.9136681642169013 0.0035720938759109 0.9999140141079672 0.0092829020780482 2 Q16850 1 +Prolyl 4-hydroxylase [IPR045054] 0.8841890315052523 2.8935854444742555 0.003808706479444 0.9999538031357156 0.0096921946986631 2 P13674 1 +SUN domain-containing protein 1-5 [IPR045119] 0.8745624270711791 2.849236703007834 0.0043824262534186 0.9999897642259924 0.0107044137058293 2 O94901 1 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.8710618436406079 2.833052803827757 0.0046105769177475 0.9999943798920272 0.011106141083635 2 Q5T9A4 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.9413481178873606 2.737047495117344 0.0061993341985262 0.9999999139154352 0.0138138486059153 3 P51116,P51114 2 +HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380] 0.92312337780966 2.6592028716275413 0.0078325783618076 0.9999999988351708 0.0164446428527196 3 P49902 1 +TAF15/EWS/TLS family [IPR034870] 0.9191712868397997 2.6422304206738128 0.0082362001954272 0.9999999995982206 0.0170863598027261 3 P35637,Q92804 2 +SLC12A transporter family [IPR004842] 0.8264294049008157 2.624007182157026 0.0086901952624562 0.9999999998787183 0.0177744728745783 2 P55011 1 +Ancient conserved domain protein family [IPR045095] 0.8255542590431768 2.619857741487803 0.0087966454092425 0.9999999999084226 0.0179146012729174 2 Q8NE01 1 +Porin, eukaryotic type [IPR001925] 0.910417274584172 2.6045191611722065 0.0092003276372696 0.9999999999684503 0.0184980874023151 3 P21796,P45880 2 +Oligosaccharyl transferase, STT3 subunit [IPR003674] 0.8179696616102721 2.583813928477766 0.0097714495501668 0.9999999999930188 0.0192776108772522 2 P46977 1 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.9039976655967296 2.5767618096177047 0.0099730647694991 0.999999999995902 0.0195720460892795 3 Q9HB40,P10619 2 +Ribosomal protein S6 kinase II [IPR016239] 0.8159276546091014 2.574084676755129 0.0100505672205344 0.9999999999966608 0.0196651337688242 2 Q15418 1 +Lysosome-associated membrane glycoprotein [IPR002000] 0.8103850641773496 2.547622850853498 0.0108459657133381 0.9999999999995922 0.0208932594301124 2 P13473 1 +Fatty acyl-CoA reductase [IPR026055] 0.8092182030338286 2.542041902990104 0.0110206960321392 0.9999999999997432 0.0211364668768888 2 Q96K12 1 +MICOS complex subunit MIC26/MIC27, animal [IPR033182] 0.7957992998833144 2.4776097605231633 0.0132265719892874 0.9999999999999992 0.0244874114111648 2 Q9BUR5 1 +MICOS complex subunit MIC26/MIC27 [IPR019166] 0.7957992998833144 2.4776097605231633 0.0132265719892874 0.9999999999999992 0.0244874114111648 2 Q9BUR5 1 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.7890898483080503 2.4452201939922693 0.01447637287736 1.0 0.026232348927846 2 P07910 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.8651882112634809 2.407103204027222 0.0160796251360786 1.0 0.0284218238891768 3 Q9NPR9,Q5VW38 2 +Defective-in-cullin neddylation protein [IPR014764] 0.8636501374980918 2.4003137979678075 0.016381022424311 1.0 0.0287988942620952 3 Q92564 1 +Aurora kinase [IPR030616] 0.7750875145857692 2.377251980442686 0.0174421683836634 1.0 0.0302230958451806 2 O14965 1 +Ribosomal protein L3 [IPR000597] 0.770128354725787 2.3530592234685845 0.0186196682736332 1.0 0.0317736804982548 2 P09001 1 +P-type ATPase, subfamily IIB [IPR006408] 0.757876312718779 2.293019000517079 0.0218469110755443 1.0 0.035831673588479 2 P20020 1 +Mitochondrial carrier protein [IPR002067] 0.7421963104015664 2.259449994193356 0.0238554075454122 1.0 0.0384035360854144 10 O75746,Q6NUK1,P12236,O43808,Q9UJS0,P12235,Q9BQT8 7 +Ribosomal protein L15 [IPR030878] 0.7497082847141237 2.2527794986581164 0.0242730554670944 1.0 0.0388736181400817 2 P46776 1 +Cyclin [IPR039361] 0.7473745624270727 2.241251379249401 0.0250097964428093 1.0 0.0398450837359252 2 O95067 1 +Eukaryotic porin/Tom40 [IPR027246] 0.9049041185993814 2.2203761611980575 0.0263932438774683 1.0 0.0415681673590952 4 P21796,P45880 2 +Ergosterol biosynthesis ERG4/ERG24 [IPR001171] 0.8193755471257574 2.202741469015499 0.0276129756502068 1.0 0.0431302782172885 3 O76062,Q14739 2 +Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756] 0.7281213535589252 2.145620755574413 0.0319032481319763 1.0 0.0484944201703951 2 Q9Y5Y2 1 +Mrp/NBP35 ATP-binding protein [IPR019591] 0.7281213535589252 2.145620755574413 0.0319032481319763 1.0 0.0484944201703951 2 Q9Y5Y2 1 +Ribosomal protein L4/L1e [IPR002136] 0.7182030338389733 2.0959958650913997 0.036082557747944 1.0 0.0532085518988847 2 P36578 1 +HnRNP R/Q splicing factor [IPR006535] 0.7957397140355779 2.0956003997707646 0.0361176537373499 1.0 0.053230299817976 3 O43390,O60506 2 +Nucleosome assembly protein (NAP) [IPR002164] 0.8725244092950676 2.0860300423146607 0.036975901825937 1.0 0.0543115997622971 4 P55209 1 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.7817332944266004 2.031575483407109 0.0421966507411282 1.0 0.0601560971873522 3 P12235,P12236 2 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.7805660927925097 2.0262224672839495 0.0427419922850662 1.0 0.0607928459497229 3 P11117,Q9NPH0 2 +PDK/BCKDK protein kinase [IPR039028] 0.7624744674642364 1.9429114017248337 0.0520268640837113 1.0 0.0712204481648293 3 Q15118,Q15120 2 +Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129] 0.6846557759626635 1.9263859778204768 0.0540561969835797 1.0 0.0734984466263226 2 O14880 1 +Major facilitator superfamily [IPR011701] 0.8341144980164873 1.924386992360602 0.0543060936755583 1.0 0.0737998654832523 4 Q96ES6,Q9H2V7 2 +Aminopeptidase N-type [IPR034016] 0.8307063631056422 1.9099296634714356 0.0561422701307345 1.0 0.0758616625320256 4 Q9UIQ6,Q9NZ08,Q6P179 3 +Tricarboxylate/iron carrier [IPR004686] 0.7546233601425509 1.906563030651167 0.0565771962582961 1.0 0.0762131541769839 3 Q6P4A7 1 +E3 ubiquitin-protein ligase, SMURF1 type [IPR024928] 0.7516067163392156 1.8925663081449744 0.0584155678355977 1.0 0.0783265635355836 3 Q96PU5 1 +Ribosomal protein L2 [IPR002171] 0.6764877479579983 1.88469331103136 0.0594712559712582 1.0 0.0792546131537501 2 Q5T653 1 +Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661] 0.6753208868144622 1.8787250469407144 0.0602820459811914 1.0 0.0800903160420502 2 O43683 1 +THRAP3/BCLAF1 family [IPR029199] 0.6718203033839014 1.8608022708980656 0.0627721047017026 1.0 0.0828515771441242 2 Q9Y2W1 1 +Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276] 0.6648191365227576 1.824876981219037 0.0680195955900102 1.0 0.0879581127352777 2 O75880 1 +Copper chaperone SCO1/SenC [IPR003782] 0.6648191365227576 1.824876981219037 0.0680195955900102 1.0 0.0879581127352777 2 O75880 1 +5'-3' exoribonuclease [IPR027073] 0.6616102683780669 1.8083763508824549 0.0705479460585889 1.0 0.0902903262667654 2 Q9H0D6 1 +Adaptor protein complex, sigma subunit [IPR016635] 0.6531505250875203 1.7647725519949926 0.0776019994592045 1.0 0.0974121068067557 2 P53680 1 +Synaptobrevin [IPR001388] 0.648483080513425 1.7406536215765185 0.0817443123933863 1.0 0.1014436058923617 2 P51809 1 +Importin subunit alpha [IPR024931] 0.771941115181525 1.7359038753423546 0.0825808324652697 1.0 0.1023360766125748 5 P52294 1 +Spectrin, beta subunit [IPR016343] 0.6455659276546171 1.7255576813974436 0.0844270182095594 1.0 0.1042664425297884 2 O15020 1 +Ribosomal protein L37/S30 [IPR010793] 0.6426487747957881 1.7104454731604466 0.0871835282934703 1.0 0.1068211044971994 2 Q9NP92 1 +Bcl2-like [IPR002475] 0.7073241902538397 1.6852732552983534 0.0919358632270923 1.0 0.1114994057496864 3 Q07820,Q9BXK5 2 +Bcl-2 family [IPR026298] 0.7073241902538397 1.6852732552983534 0.0919358632270923 1.0 0.1114994057496864 3 Q07820,Q9BXK5 2 +P-type ATPase [IPR001757] 0.7585401459853727 1.6763176677222975 0.0936759860563121 1.0 0.113149844551474 5 P20020,Q9HD20,P05023,P16615 4 +H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504] 0.6359393232205252 1.6756273598634617 0.0938112062372942 1.0 0.1132487842716943 2 Q9NY12 1 +Ribosomal protein S5/S7 [IPR000235] 0.6338973162193617 1.6650143931256245 0.0959098843225261 1.0 0.1152504627412624 2 P46782 1 +A-kinase anchoring protein 95 (AKAP95) [IPR007071] 0.6959439743215512 1.6314961202084215 0.1027856778449436 1.0 0.122277095608173 3 Q5BKZ1,Q9ULX6 2 +Peptidase M3A/M3B [IPR045090] 0.6950431814557438 1.6272316031165177 0.1036879180904453 1.0 0.1231158635077931 3 Q99797 1 +Peptidase, FtsH [IPR005936] 0.6266044340723533 1.6270519905504843 0.1037260562580948 1.0 0.1231158635077931 2 Q9Y4W6 1 +Flotillin family [IPR027705] 0.6158109684947484 1.57070871700169 0.116250323480024 1.0 0.1346815085136151 2 O75955 1 +Type 1 protein exporter [IPR039421] 0.7107579731779397 1.5399035627562794 0.1235838622367162 1.0 0.141177023411026 6 P08183,Q03518,Q03519,Q9NUT2 4 +Plakophilin/Delta catenin [IPR028435] 0.6761675184014562 1.537629651102579 0.1241391932907562 1.0 0.1416258742471079 3 Q99959 1 +Proteasome B-type subunit [IPR023333] 0.6564985023590377 1.462920676686663 0.143489085502825 1.0 0.1595950032633462 7 P49721,P28072 2 +YTH domain containing protein [IPR045168] 0.6447420336691452 1.3876256131884348 0.1652510778965119 1.0 0.1787828038781121 3 Q96MU7 1 +Tubulin [IPR000217] 0.6703081321686463 1.3516252116618372 0.1764952408684323 1.0 0.1880698778459548 6 P04350,P07437,Q13885,P68371 4 +Beta tubulin [IPR002453] 0.6703081321686463 1.3516252116618372 0.1764952408684323 1.0 0.1880698778459548 6 P04350,P07437,Q13885,P68371 4 +Syntaxin [IPR045242] 0.6837956204379482 1.3403224343453843 0.1801405409076291 1.0 0.1910979947341272 5 Q86Y82,Q13190,Q13277,Q9UNK0 4 +FAM98 [IPR018797] 0.5694282380396852 1.326976201672326 0.184516555162046 1.0 0.1948709359321406 2 Q52LJ0 1 +Heat shock protein Hsp90 family [IPR001404] 0.6776489007317615 1.3125148002022693 0.189346495665291 1.0 0.1989278846025708 5 Q58FF6,P14625,P07900 3 +Pre-mRNA-splicing factor Syf1-like [IPR045075] 0.6157878712782683 1.2489167644401964 0.2116955192461018 1.0 0.2212526881133849 3 Q9BZJ0 1 +Transmembrane emp24 domain-containing protein [IPR015720] 0.6477573352821928 1.1772506093895676 0.2390954940539642 1.0 0.2488952695762716 5 P49755,Q9Y3B3,Q15363 3 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.6182056916386808 1.108319258509603 0.2677239611053128 1.0 0.27792296914742 6 Q9UIQ6,Q9NZ08,Q6P179 3 +Non-specific endonuclease [IPR040255] 0.5157526254375834 1.0444611475297438 0.2962720857306165 1.0 0.3070712267318909 2 Q9Y2C4 1 +CTP synthase [IPR004468] 0.5134189031505424 1.032253816321021 0.3019532301383243 1.0 0.3128355049670718 2 P17812 1 +Sla2 family [IPR030224] 0.5090431738623267 1.009397431474185 0.3127840697945965 1.0 0.3239283953217198 2 O75146 1 +Protein arginine N-methyltransferase [IPR025799] 0.5901873917616154 0.9186428202624332 0.3582824269137088 1.0 0.3700224353755477 5 Q6P2P2 1 +Sulfurtransferase TST/MPST-like [IPR045078] 0.4775379229871731 0.8465500969995231 0.397245939218424 1.0 0.4092931772333191 2 Q16762 1 +Short-chain dehydrogenase/reductase SDR [IPR002347] 0.4195889412634515 0.8330309099589529 0.4048272968941298 1.0 0.416776154535633 17 Q96LJ7,Q06136,Q3SXM5 3 +Sister chromatid cohesion protein Pds5 [IPR039776] 0.4693698949825119 0.8049984342837124 0.420820583304617 1.0 0.4329007652083673 2 Q29RF7 1 +Paraneoplastic encephalomyelitis antigen [IPR002343] 0.4658693115519406 0.7872990280806238 0.4311068385115151 1.0 0.4431337876409129 2 Q15717 1 +Pyrroline-5-carboxylate reductase [IPR000304] 0.465285880980177 0.7843558959247748 0.4328313097631155 1.0 0.4440896969355006 2 Q96C36 1 +Desmosomal cadherin [IPR009122] 0.4501166861143728 0.7085873100392981 0.4785806134759198 1.0 0.4905826351304884 2 Q14126 1 +Ribosomal protein S5 [IPR000851] 0.4469078179696695 0.6927639937521037 0.4884576717189377 1.0 0.5003152972657561 2 P82675 1 +Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309] 0.4445740956826235 0.6813057292627606 0.4956780588278584 1.0 0.507313694011611 2 O95478 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666] 0.4331971995332781 0.6260942042744837 0.5312531534791174 1.0 0.5428743162114731 2 Q96BP3 1 +Kinesin light chain [IPR002151] 0.4707763859444 0.5762901348764561 0.5644190897803834 1.0 0.5754171234861586 3 Q9NSK0 1 +Phosphatidylinositol kinase [IPR015433] 0.4194865810968644 0.5611712143948046 0.5746808243327237 1.0 0.585650579062877 2 O00443 1 +Translin family [IPR002848] 0.4174445740956856 0.5516708278029425 0.5811739002541452 1.0 0.5915203762131707 2 Q15631 1 +Gamma-tubulin complex component protein [IPR007259] 0.4171528588098178 0.5503174416946157 0.5821016632292555 1.0 0.5920598565348882 2 Q96CW5 1 +Ribosomal protein L1/ribosomal biogenesis protein [IPR028364] 0.4482054274876161 0.481996362062799 0.6298085305948673 1.0 0.638844170622789 3 Q9BYD6,O76021 2 +Sec1-like protein [IPR001619] 0.484719628215291 0.4746723397713526 0.6350205361155177 1.0 0.6438812877822458 5 O00186,Q9H267 2 +Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909] 0.3973162193698953 0.4607224503842885 0.6449977458448326 1.0 0.6534911321185446 2 Q9HA77 1 +Cysteine-tRNA ligase [IPR015803] 0.3973162193698953 0.4607224503842885 0.6449977458448326 1.0 0.6534911321185446 2 Q9HA77 1 +HnRNP-L/PTB [IPR006536] 0.48807897363281 0.4542643530964678 0.649638569692651 1.0 0.6579382494448219 4 P14866,Q9UKA9 2 +Polyprenyl synthetase [IPR000092] 0.4298060091885685 0.4091666450312393 0.682417370563762 1.0 0.6906010991856097 3 Q5T2R2 1 +Glutathione Transferase family [IPR040079] 0.3924692784858742 0.3989512272322097 0.6899291420767524 1.0 0.697932960430311 11 Q13505,O15217,Q8TB36 3 +G-protein alpha subunit, group I [IPR001408] 0.4236941931718793 0.3859013525613198 0.6995697288731746 1.0 0.7071384894637653 3 P63096,P04899 2 +Protein kinase C, alpha/beta/gamma types [IPR014375] 0.3792298716452734 0.3838298575645413 0.7011045568312535 1.0 0.7084161918387637 2 P05771 1 +DNA mismatch repair MutS family [IPR045076] 0.4111467756054972 0.3397440133503705 0.7340493132883354 1.0 0.7408460661891533 3 P52701,P20585 2 +DNA-directed DNA polymerase, family B [IPR006172] 0.406298385559022 0.3225228958738723 0.7470565952820782 1.0 0.7536830132116917 3 Q07864 1 +Oxysterol-binding protein [IPR000648] 0.4345834970653465 0.3213651941728545 0.7479336563649595 1.0 0.754276964167592 6 P22059,Q9BZF1 2 +Myotubularin family [IPR030564] 0.3491831971995313 0.2685685649863399 0.7882617052663854 1.0 0.7931125465295632 2 Q9Y217 1 +Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019] 0.4238178633975547 0.2418142394556731 0.8089241048159495 1.0 0.8120281881038081 4 Q14344,P63096,P04899 3 +Linker histone H1/H5 [IPR005819] 0.4072992700729968 0.2117168773932151 0.832327920312979 1.0 0.834561073031335 5 P16403,P10412,P16402,P07305 4 +Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737] 0.3656259118762855 0.1933833075025543 0.8466587873730675 1.0 0.8482801178735905 3 Q9UNQ2,Q9H5Q4 2 +Histone deacetylase family [IPR000286] 0.2935665431597365 0.0426507271847397 0.9659799578069131 1.0 0.9667190396415016 3 Q9UBN7 1 +Proteasome activator PA28 [IPR009077] 0.2646134551763458 0.0102923383576813 0.9917880471151816 1.0 0.9921673159668508 3 Q9UL46 1 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8ad1bc55931ce89ea801fcf9b9fb6ac9d718d017 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "-alpha-acetyltransferase 35, NatC auxiliary subunit [IPR007244]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1,4-alpha-glucan-branching enzyme [IPR037439]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 [IPR028381]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S26 [IPR026140]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3'-5' RNA helicase YTHDC2-like [IPR031083]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-keto-steroid reductase [IPR042829]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "4-aminobutyrate aminotransferase, eukaryotic [IPR004631]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease 1 [IPR016494]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5'-deoxynucleotidase YfbR/HDDC2 [IPR039356]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 9/Pericentrin [IPR028745]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "A1 cistron-splicing factor, AAR2 [IPR007946]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABI family [IPR028457]", "ABT1/Esf2 [IPR039119]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 15 [IPR042292]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "ALG11 mannosyltransferase [IPR038013]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Abl interactor 1 [IPR028456]", "Abr/Bcr [IPR037769]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-histidine N-methyltransferase SETD3 [IPR025785]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 1 [IPR017383]", "Actin-related protein 2/3 complex subunit 1A [IPR030140]", "Actin-related protein 2/3 complex subunit 1B [IPR030141]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-coenzyme A diphosphatase NUDT19 [IPR039121]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein Cbl [IPR024162]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine kinase [IPR001805]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase isoenzyme 6 [IPR020618]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "Adenylyltransferase and sulfurtransferase MOCS3/Uba4 [IPR028885]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase [IPR011408]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha crystallin/Small heat shock protein, animal type [IPR001436]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid beta precursor protein binding family B member 1/2/3 [IPR039576]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Ankyrin repeat and SAM domain-containing protein 1A [IPR033637]", "Ankyrin repeat domain-containing protein 13 [IPR021832]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A3 [IPR002390]", "Annexin A4 [IPR002391]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Antigen peptide transporter 2 [IPR005293]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAX [IPR026304]", "Apoptosis regulator, Mcl-1 [IPR013281]", "ArfGAP ACAP1/2/3-like [IPR045258]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Arginine-tRNA-protein transferase 1, eukaryotic [IPR017137]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Armadillo-type fold containing protein ARMC8/Vid28 [IPR038739]", "Arrestin [IPR000698]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arsenite methyltransferase-like [IPR026669]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparaginase-like 1, metazoa [IPR033844]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atg6/Beclin [IPR007243]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 9 [IPR007241]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BEN domain-containing protein 3 [IPR033583]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRISC and BRCA1-A complex member 1 [IPR026126]", "BRO1 domain-containing protein BROX [IPR038898]", "BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1/2/3 [IPR045068]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beclin-1 [IPR032913]", "Beta tubulin [IPR002453]", "Beta-1,4-galactosyltransferase [IPR003859]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-2-syntrophin [IPR028550]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-adducin [IPR027773]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-ketoacyl synthase [IPR000794]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biogenesis of lysosome-related organelles complex 1 subunit 1 [IPR009395]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bromodomain-containing protein 8 [IPR038002]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "C2 domain-containing protein 5 [IPR038983]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT complex, subunit 3/ 5 [IPR012270]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 10 [IPR039740]", "CCR4-NOT transcription complex subunit 11 [IPR019312]", "CCR4-NOT transcription complex subunit 4 [IPR039780]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDCA7/CDA7L [IPR040221]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CEBPZ/Mak21-like [IPR040155]", "CGI121/TPRKB [IPR013926]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMM domain-containing protein 2 [IPR037354]", "COMM domain-containing protein 7 [IPR037358]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome complex subunit 7B [IPR027530]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPSF6/7 family [IPR034772]", "CTD phosphatase Fcp1 [IPR039189]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin-2 [IPR029974]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calsyntenin [IPR026914]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carboxymethylenebutenolidase homolog [IPR042946]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Caspase-3/7 [IPR015471]", "Cat eye syndrome critical region protein 2 [IPR029614]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle checkpoint, Hus1 [IPR016580]", "Cell division cycle-associated 7-like protein [IPR033578]", "Cell division cycle-associated protein 2 [IPR033064]", "Cell division protein Cdc6/18 [IPR016314]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-F [IPR043513]", "Centromere protein U [IPR025214]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 290kDa [IPR026201]", "Centrosomal protein of 44kDa [IPR033603]", "Centrosomal protein of 55kDa [IPR038926]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Checkpoint protein Hus1/Mec3 [IPR007150]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin complexes subunit BAP18 [IPR037931]", "Chromatin modification-related protein Eaf7/MRGBP [IPR012423]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Chromosome transmission fidelity protein 8 [IPR018607]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cilia- and flagella-associated protein 298 [IPR021298]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Citron Rho-interacting kinase [IPR017405]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil and C2 domain-containing protein 1 [IPR039725]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 127 [IPR034607]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit G2 [IPR024741]", "Conserved oligomeric Golgi complex subunit 5 [IPR019465]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex subunit 8 [IPR007255]", "Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae [IPR016632]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Copper homeostasis protein CutC [IPR005627]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Core-binding factor, beta subunit [IPR003417]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin [IPR039361]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cysteine oxygenase/2-aminoethanethiol dioxygenase [IPR012864]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit VIb [IPR003213]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "Cytospin-A [IPR040166]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 15 [IPR038914]", "DDB1- and CUL4-associated factor 16 [IPR028216]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair protein XRCC4 [IPR010585]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-binding protein SATB1/SATB2 [IPR039673]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase I, subunit RPA34.5 [IPR013240]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase III subunit Rpc5 [IPR006886]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "DeoC/FbaB/LacD aldolase [IPR002915]", "Deoxycytidylate deaminase [IPR016473]", "Deoxycytidylate deaminase-related [IPR015517]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyribose-phosphate aldolase [IPR011343]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Diacylglycerol kinase [IPR037607]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 3 [IPR030628]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone kinase [IPR012734]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dim1 family [IPR004123]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphosphomevalonate decarboxylase [IPR029765]", "Diphosphomevalonate/phosphomevalonate decarboxylase [IPR005935]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Divalent ion tolerance protein, CutA [IPR004323]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase Nse2 (Mms21) [IPR026846]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF213 [IPR031248]", "E3 ubiquitin-protein ligase UBR1-like [IPR039164]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "ETS family [IPR046328]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongin B [IPR039049]", "Emerin [IPR035004]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosulphine [IPR006760]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Est1/Ebs1-like [IPR045153]", "Esterase-like [IPR000801]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Eukaryotic-type methylenetetrahydrofolate reductase [IPR004621]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-6 [IPR040016]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Eyes absent family [IPR028472]", "Eyes absent homologue 4 [IPR028478]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM105 [IPR023235]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM20 [IPR024869]", "FAM91 [IPR039199]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FLYWCH-type zinc finger-containing protein 1/2 [IPR040312]", "FMP27 [IPR045167]", "FUN14 [IPR007014]", "FYVE and coiled-coil domain-containing protein 1 [IPR042654]", "Fanconi anaemia group A protein [IPR003516]", "Fanconi anaemia protein FANCD2 [IPR029448]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 2 [IPR030305]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "FeS cluster insertion protein [IPR016092]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Focadhesin [IPR021392]", "Focadhesin/RST1 [IPR045163]", "Folliculin [IPR021713]", "Forkhead box protein C1 [IPR033067]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "G2 and S phase-expressed protein 1 [IPR026659]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GDP-mannose 4,6-dehydratase [IPR006368]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf1 [IPR005339]", "GINS complex, subunit Psf3 [IPR010492]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI transamidase subunit PIG-U [IPR009600]", "GPI-anchor transamidase [IPR028361]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP cyclohydrolase 1 type 2/Nif3 [IPR002678]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "GTP-binding protein, ribosome biogenesis, YsxC [IPR019987]", "GTPase HflX [IPR016496]", "Galactokinase [IPR000705]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Ganglioside-induced differentiation-associated protein 1 [IPR034336]", "Gem-associated protein 4 [IPR033265]", "Gemin6 [IPR009422]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Glomulin/ALF4 [IPR019516]", "Glucosamine 6-phosphate N-acetyltransferase [IPR039143]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutamate/phenylalanine/leucine/valine dehydrogenase [IPR006095]", "Glutaminase [IPR015868]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, alpha class [IPR003080]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glutathione-specific gamma-glutamylcyclotransferase [IPR006840]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent [IPR006168]", "Glycerol-3-phosphate dehydrogenase, NAD-dependent, eukaryotic [IPR017751]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 8 [IPR002495]", "Glycosyltransferase 61 [IPR007657]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanidinoacetate N-methyltransferase [IPR016550]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor Ect2 [IPR026817]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-binding protein, beta subunit [IPR016346]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HCLS1-binding protein 3 [IPR039701]", "HMG-CoA lyase [IPR043594]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Hermansky-Pudlak syndrome 5 protein [IPR035431]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine acid phosphatase, eukaryotic [IPR016274]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histidine-tRNA ligase [IPR015807]", "Histidine-tRNA ligase/ATP phosphoribosyltransferase regulatory subunit [IPR004516]", "Histone H2A [IPR002119]", "Histone H3/CENP-A [IPR000164]", "Histone H4 [IPR001951]", "Histone PARylation factor 1 [IPR019361]", "Histone acetyltransferase Rtt109/CBP [IPR013178]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone methyltransferase complex subunit ASH2 [IPR037353]", "Histone-lysine N-methyltransferase 2A [IPR037927]", "Histone-lysine N-methyltransferase EHMT1 [IPR038035]", "Histone-lysine N-methyltransferase EHMT1/EHMT2 [IPR043550]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETD2, animal [IPR042294]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "Histone-lysine N-methyltransferase, SET [IPR017155]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin [IPR000091]", "Huntingtin family [IPR028426]", "Huntingtin-interacting protein 1 [IPR030554]", "Huntingtin-interacting protein 1-related protein [IPR030555]", "Hyccin [IPR018619]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxyacylglutathione hydrolase [IPR017782]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "Immunity-related GTPase family Q protein [IPR040070]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inactive ubiquitin thioesterase OTULINL [IPR023236]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 12 [IPR039053]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 7 [IPR033060]", "Integrator complex subunit 8 [IPR038751]", "Integrator complex subunit 9 [IPR027074]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interferon-stimulated 20kDa exonuclease-like 2 [IPR034933]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Interleukin-1 receptor-associated kinase 1 [IPR035536]", "Intermembrane space protein MIX23 [IPR019171]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intracellular lipid binding protein [IPR031259]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intraflagellar transport protein 52 homolog [IPR039975]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isoamyl acetate-hydrolyzing esterase Iah1-like [IPR045136]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Katanin p80 WD40 repeat-containing subunit B1 [IPR026962]", "Keratin, type I [IPR002957]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore protein Ndc80 [IPR005550]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Kintoun [IPR034727]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Learning associated protein 18-like [IPR018784]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat flightless-interacting protein 1/2 [IPR019139]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-rich repeat-containing protein 14 [IPR026292]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte elastase inhibitor (serpin B1) [IPR015557]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Liprin-alpha-1 [IPR030438]", "Liprin-beta-1 [IPR030437]", "LisH domain-containing protein ARMC9 [IPR040369]", "Lon protease [IPR027065]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lunapark family [IPR040115]", "Lupus La protein [IPR002344]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase inducer phosphatase [IPR000751]", "M-phase phosphoprotein 6 [IPR019324]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICAL-like protein [IPR028563]", "MICAL3 [IPR029941]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MICRORCHIDIA ATPase family [IPR045261]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Magnesium transporter protein 1 [IPR006844]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannosyltransferase ALG2 [IPR027054]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med16 [IPR021665]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D1 [IPR030083]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylenetetrahydrofolate reductase-like [IPR003171]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylmalonic aciduria and homocystinuria type C family [IPR032037]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribulose-1-phosphate dehydratase [IPR017714]", "Methylthioribulose-1-phosphate dehydratase, eukaryotes [IPR027514]", "Methylthiotransferase [IPR005839]", "Methyltransferase Ppm1/Ppm2/Tcmp [IPR007213]", "Methyltransferase, trithorax [IPR016569]", "Mevalonate/galactokinase [IPR006206]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microspherule protein 1 [IPR037912]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Minichromosome maintenance protein 10 [IPR040184]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial dynamics protein MID49/MID51 [IPR045909]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial transcription factor TFB2 [IPR016861]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-1 [IPR027088]", "Mitogen-activated protein (MAP) kinase kinase kinase 7 [IPR017421]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitoguardin [IPR019392]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdenum cofactor biosynthesis C [IPR023045]", "Molybdenum cofactor biosynthesis protein A [IPR013483]", "Molybdopterin biosynthesis MoaE [IPR003448]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Molybdopterin synthase catalytic subunit, eukaryotes [IPR028888]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multidrug resistance protein 1 [IPR030258]", "Multiple PDZ domain protein [IPR032078]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myotubularin family [IPR030564]", "Myotubularin-related protein 6 [IPR030581]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetyltransferase B complex, non-catalytic subunit [IPR019183]", "N-acyl-L-amino-acid amidohydrolase [IPR010159]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-end rule aminoacyl transferase [IPR030700]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B/Dorsal [IPR000451]", "NIF3-like protein 1, animal [IPR017222]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "Nck-associated protein 1 [IPR019137]", "Nectin-2 [IPR033318]", "Negative cofactor 2 complex subunit beta [IPR042225]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neural cell adhesion [IPR009138]", "Neural cell adhesion molecule 1 [IPR033019]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neurogenic locus Notch 2 [IPR022336]", "Neuropilin [IPR014648]", "Neuropilin-1 [IPR027146]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Notch [IPR008297]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 2 [IPR027157]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear speckle splicing regulatory protein 1 [IPR042816]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar pre-ribosomal-associated protein 1 [IPR039844]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase 7 [IPR011410]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 1 [IPR037895]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "Occludin [IPR002958]", "Octamer-binding transcription factor [IPR000972]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Opioid growth factor receptor [IPR039574]", "Origin recognition complex, subunit 3 [IPR020795]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PCNA-associated factor [IPR040444]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Pat1-like [IPR039900]", "Patatin-like phospholipase domain-containing protein 4 [IPR033902]", "Patatin-like phospholipase domain-containing protein [IPR033562]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C14 family [IPR002398]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C50, separase [IPR005314]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1A, Tysnd1 [IPR017345]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase T2, asparaginase 2 [IPR000246]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxisomal/glyoxysomal leader peptide-processing protease [IPR039245]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin [IPR001200]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 17 [IPR032847]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor 18 [IPR039979]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor SLU7 [IPR039974]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable methyltransferase TARBP1 [IPR025806]", "Probable methyltransferase Trm3/TARBP1 [IPR045330]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Progesterone-induced-blocking factor 1 [IPR026205]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa [IPR002316]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Proline/serine-rich coiled-coil protein 1/G2 and S phase-expressed protein 1 [IPR026657]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome maturation factor Ump1 [IPR008012]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein CIP2A [IPR042510]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM8A1 [IPR039871]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LIN-9/Protein ALWAYS EARLY [IPR010561]", "Protein LYRIC [IPR031402]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NDRG1 [IPR030693]", "Protein NDRG3 [IPR030692]", "Protein OS-9-like [IPR045149]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein S100-A13 [IPR028487]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein XRP2 [IPR039093]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein diaphanous homologue 2 [IPR027644]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein farnesyltransferase subunit beta [IPR026872]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, alpha/beta/gamma types [IPR014375]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase Mps1 family [IPR027084]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4726 [IPR031714]", "Protein of unknown function DUF719 [IPR007998]", "Protein of unknown function DUF842, eukaryotic [IPR008560]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein strawberry notch [IPR026741]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein virilizer [IPR026736]", "Protein wntless [IPR009551]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Proto-oncogene c-Rel [IPR030505]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative RNA-binding protein 47 [IPR034442]", "Putative hydrolase RBBP9/YdeN [IPR010662]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxamine 5'-phosphate oxidase [IPR000659]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "RAB11-binding protein RELCH [IPR040362]", "RAD3/XPD family [IPR001945]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II subunit A [IPR006811]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit Pop5/Rpp14/Rnp2-like [IPR002759]", "RNase P subunit p30 [IPR002738]", "ROK family [IPR000600]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab protein geranylgeranyltransferase component A [IPR001738]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab3 [IPR037872]", "Rab35 [IPR041815]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Ran-interacting Mog1 protein [IPR007681]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein [IPR039360]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab-23 [IPR034114]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Refilin family [IPR028215]", "Regulator of MON1-CCZ1 complex [IPR040371]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Replication termination factor 2 [IPR006735]", "Reticulophagy receptor 1/3 [IPR043384]", "Reticulophagy regulator 3 [IPR033361]", "Retinoblastoma protein family [IPR028309]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho GDP/GTP exchange factor Kalirin/TRIO [IPR028570]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2 subunit B [IPR040456]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S27/S33, mitochondrial [IPR013219]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAP30-binding protein [IPR012479]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SPRY domain-containing protein 7 [IPR035766]", "SSNA1 family [IPR033362]", "STEEP-like [IPR029704]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Sarcolemmal membrane-associated protein [IPR030498]", "Sas10/Utp3/C1D [IPR007146]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sds3-like [IPR013907]", "Sec1-like protein [IPR001619]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase ATM/Tel1 [IPR015519]", "Serine/threonine-protein kinase Atg1-like [IPR045269]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase Rio1 [IPR017407]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit [IPR037981]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Shikimate kinase/Threonine synthase-like 1 [IPR000623]", "Shikimate kinase/gluconokinase [IPR031322]", "Shootin-1 [IPR024849]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sialidase family [IPR026856]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sirtuin, class I [IPR017328]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small kinetochore-associated protein [IPR033373]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snapin [IPR017246]", "Snapin/Pallidin/Snn1 [IPR028119]", "Snf7 family [IPR005024]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 12 member 9 [IPR030345]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-4 [IPR034783]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-8/Mvp1 [IPR028662]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spectrin, beta subunit [IPR016343]", "Sperm-associated antigen 5 [IPR028728]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermatogenesis-defective protein 39 [IPR040057]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle and kinetochore-associated protein 3 [IPR033341]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 3B subunit 5/RDS3 complex subunit 10 [IPR009846]", "Splicing factor 3B, subunit 5 [IPR017089]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Steroid receptor RNA activator 1 [IPR040243]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptobrevin [IPR001388]", "Syntaxin [IPR045242]", "Syntaxin-3 [IPR031186]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "Syntrophin [IPR015482]", "T-complex 11 [IPR008862]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA-binding protein-associated factor Mot1 [IPR044972]", "TB2/DP1/HVA22-related protein [IPR004345]", "TE2IP/Rap1 [IPR039595]", "TFIIH subunit Tfb1/GTF2H1 [IPR027079]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM192 family [IPR029399]", "TMEM33/Pom33 family [IPR005344]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TNF receptor-associated factor 2 [IPR027133]", "TNF receptor-associated factor TRAF [IPR043211]", "TNF receptor-associated factor TRAF, metazoa [IPR012227]", "TPMT family [IPR008854]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TRAPP III complex, Trs85 [IPR024420]", "TREX component Tex1/THOC3 [IPR040132]", "Tankyrase 1-binding protein-like [IPR040006]", "Tapasin [IPR008056]", "Target of Myb protein 1 [IPR014645]", "Target of Myb1-like 2 [IPR027429]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Telomeric repeat-binding factor 1/2 [IPR017357]", "Telomeric repeat-binding factor 2 [IPR030657]", "Teneurin-3/4 [IPR027691]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "Tetratricopeptide repeat protein TTC27/Emw1 [IPR044244]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thiopurine S-methyltransferase [IPR025835]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine synthase-like [IPR004450]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit 13 [IPR010378]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor RelA (p65) [IPR030495]", "Transcription factor STAT [IPR001217]", "Transcription factor Spt20 [IPR021950]", "Transcription factor TFIIB [IPR000812]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor, enhancer of yellow 2 [IPR018783]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TFIID subunit 6 [IPR037796]", "Transcription initiation factor TFIIE, beta subunit [IPR016656]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription termination factor, mitochondrial/chloroplastic [IPR003690]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Translocon-associated protein subunit gamma [IPR009779]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transport protein particle (TRAPP) component [IPR007194]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Trimethyllysine dioxygenase [IPR012776]", "Trinucleotide repeat-containing gene 6A protein [IPR033501]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "TspO/MBR-related protein [IPR004307]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U4/U6.U5 small nuclear ribonucleoprotein component Snu23 [IPR040107]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UBX domain-containing protein 2/7 [IPR017346]", "UDP-N-acetylglucosamine 2-epimerase,UDP-hydrolysing [IPR020004]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 4-epimerase [IPR005886]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin thioesterase otulin [IPR023237]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3A [IPR017134]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Ubiquitously expressed transcript protein UXT [IPR003994]", "Uncharacterised conserved protein UCP013899, metal binding [IPR016617]", "Uncharacterised protein family UPF0449 [IPR028227]", "Unconventional myosin-XVIIIa [IPR031244]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting-associated Vps28 [IPR007143]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vang-like protein [IPR009539]", "Vasodilator-stimulated phosphoprotein [IPR034367]", "Vasodilator-stimulated phosphoprotein/ENA/VASP-like [IPR017354]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Vma22/CCDC115 [IPR040357]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps72/YL1 family [IPR008895]", "WASH complex subunit 3 [IPR019309]", "WASH complex subunit 7 [IPR027307]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat and coiled-coil-containing protein family [IPR028041]", "WD repeat domain phosphoinositide-interacting protein 2 [IPR032911]", "WD repeat protein 35 [IPR017233]", "WD repeat-containing protein 11 [IPR039694]", "WD repeat-containing protein 41 [IPR040102]", "WD repeat-containing protein 47 [IPR040067]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR48/Bun107 [IPR021772]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "Xaa-Arg dipeptidase [IPR017144]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yippee family [IPR039058]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCCH domain-containing protein A/B [IPR039691]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger Ran-binding domain-containing protein 2 [IPR017337]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein RRP36 [IPR009292]", "rRNA biogenesis protein Rrp5 [IPR045209]", "tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 [IPR014816]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7 [IPR028590]", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit [IPR028884]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG [IPR004416]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG-related [IPR002218]", "tRNA-guanine transglycosylase [IPR004803]", "tRNA-specific 2-thiouridylase [IPR004506]"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACADM", "ACAP2", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKT1S1", "ALDH16A1", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANKLE2", "ANKRD13A", "ANKS1A", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEX1", "API5", "APIP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFIP1", "ARG2", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC6", "ARMC8", "ARMC9", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARVCF", "AS3MT", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATE1", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATM", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "AURKA", "AURKB", "B3GALT6", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BANF1", "BAP18", "BAX", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BDH2", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD8", "BRI3BP", "BRIX1", "BRMS1L", "BROX", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUD23", "BUD31", "BYSL", "C12orf73", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C21orf59", "C2CD2L", "C2CD5", "C2orf49", "C3orf58", "C5orf51", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASP3", "CASP7", "CAST", "CBFB", "CBL", "CBR1", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC115", "CCDC124", "CCDC127", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD3EAP", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK5RAP3", "CDKAL1", "CEBPZ", "CECR2", "CELF2", "CENPB", "CENPF", "CENPU", "CEP170", "CEP290", "CEP44", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHM", "CHMP5", "CHMP7", "CHORDC1", "CHTF8", "CIAPIN1", "CIP2A", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG5", "COG7", "COG8", "COIL", "COLGALT1", "COMMD2", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRNKL1", "CROT", "CRTAP", "CS", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWF19L1", "CXorf56", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF15", "DCAF16", "DCAF7", "DCAKD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEK", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX29", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DIDO1", "DIEXF", "DIMT1", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DR1", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EFHD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELF2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXTL3", "EYA4", "EZR", "FABP5", "FADS2", "FAH", "FAM105A", "FAM114A2", "FAM120A", "FAM120B", "FAM126A", "FAM129B", "FAM136A", "FAM162A", "FAM20B", "FAM213A", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FN3KRP", "FNTB", "FOCAD", "FOXC1", "FRYL", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYCO1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GALE", "GALK1", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBE1", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMDS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRPEL1", "GRSF1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP6", "GTPBP8", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDDC2", "HDHD2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELZ", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPF1", "HPRT1", "HPS5", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90AB4P", "HSP90B1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS12", "INTS14", "INTS3", "INTS7", "INTS8", "INTS9", "IPO4", "IPO5", "IRAK1", "IRGQ", "IRS4", "ISCA2", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "JAGN1", "JPT2", "JUP", "KARS", "KATNB1", "KCTD10", "KDELR1", "KDELR3", "KDM1A", "KDM3B", "KDSR", "KHDRBS1", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA1468", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNSTRN", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN9", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMF2", "LNPEP", "LNPK", "LONP1", "LRPAP1", "LRPPRC", "LRRC14", "LRRC41", "LRRC47", "LRRFIP1", "LSM12", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LZTFL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAK16", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP3K7", "MAP4", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP2", "MFAP1", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGST2", "MGST3", "MICAL3", "MICALL1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMACHC", "MMS19", "MOCS1", "MOCS2", "MOCS3", "MOGS", "MON2", "MORC3", "MORF4L1", "MOV10", "MPC2", "MPDZ", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL4", "MRPL40", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFR", "MTIF2", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTR", "MTX1", "MTX2", "MVD", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA15", "NAA25", "NAA35", "NAA40", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB4", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4L", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NEU1", "NF1", "NHP2", "NIF3L1", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME3", "NME7", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRM", "NRP1", "NSA2", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT19", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCLN", "OGDH", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTULIN", "OXA1L", "OXCT1", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAK2", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARS2", "PATL1", "PAWR", "PAXBP1", "PBDC1", "PBRM1", "PC", "PCBD1", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDCL", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXP", "PEBP1", "PELO", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITPNB", "PKM", "PKMYT1", "PKP2", "PLA2G15", "PLBD2", "PLCG1", "PLCG2", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA4", "PNPO", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLD2", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "POMP", "PON2", "POP1", "POR", "POU2F1", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPFIBP1", "PPIE", "PPIH", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CC", "PPP1R12A", "PPP2R1A", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF18", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB36", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RASAL2", "RAVER1", "RB1", "RBBP5", "RBBP6", "RBBP9", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM45", "RBM47", "RBM5", "RBM6", "RBM8A", "RCC2", "RCL1", "RDH11", "RDH13", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "RER1", "RETREG3", "REXO2", "REXO4", "RFC1", "RFLNB", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK1", "RIOX2", "RMC1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCB", "RTFDC1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARS", "SARS2", "SART1", "SATB2", "SBDS", "SBNO1", "SCAF1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCO1", "SCO2", "SCPEP1", "SCRN1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SF3B5", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHTN1", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLFN11", "SLK", "SLMAP", "SLTM", "SLU7", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMCHD1", "SMG5", "SMG8", "SMIM12", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAPIN", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX2", "SNX27", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SPAG5", "SPAG9", "SPART", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1L", "SPNS1", "SPR", "SPRYD7", "SPTBN1", "SPTBN2", "SQLE", "SRA1", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STARD3", "STAT1", "STAT3", "STIP1", "STMN1", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX12", "STX3", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SYMPK", "SYNCRIP", "SYNE2", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAP2", "TAPBP", "TARBP1", "TARS", "TARS2", "TARSL2", "TBCA", "TBCD", "TBCE", "TBL2", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TECR", "TEFM", "TENM3", "TERF2", "TERF2IP", "TES", "TEX10", "TFB1M", "TFB2M", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TM7SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM160", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM33", "TMEM43", "TMEM87A", "TMEM97", "TMLHE", "TMOD1", "TMOD3", "TMX2", "TNKS1BP1", "TNPO1", "TNPO2", "TNRC6A", "TOE1", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP2", "TPRKB", "TPT1", "TPX2", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC13", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM28", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNL4A", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBR1", "UBR2", "UBR4", "UBR7", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP3", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "WAPL", "WARS", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDCP", "WDR11", "WDR12", "WDR18", "WDR33", "WDR35", "WDR4", "WDR41", "WDR46", "WDR47", "WDR48", "WDR74", "WDR82", "WDR91", "WFS1", "WIPI2", "WLS", "WTAP", "WWP2", "XAB2", "XPO1", "XPO4", "XPO5", "XPO6", "XPO7", "XPOT", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YLPM1", "YME1L1", "YPEL5", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H14", "ZC3H7A", "ZC3H7B", "ZCCHC3", "ZCRB1", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZNF326", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10"], "leading_proteins": ["ABCB1", "ABCB8", "ACOX3", "ACP2", "ACP6", "AFG3L2", "AKAP8L", "AP2S1", "APOO", "ATAD3B", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP6V0A2", "AURKA", "BCL2L13", "BUB1", "CARS2", "CCNB2", "CLPTM1", "CNNM3", "CRNKL1", "CTPS1", "CTSA", "CYP51A1", "DCUN1D4", "DHRS1", "DIMT1", "DSG2", "ELAVL1", "ERAP1", "ERAP2", "EXOG", "FAM98B", "FAR2", "FLOT1", "FUS", "FXR1", "FXR2", "GAR1", "GDAP1", "GNA13", "GNAI1", "GNAI2", "GPR107", "GPR108", "GSTA4", "H1F0", "HDAC6", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HMOX2", "HNRNPC", "HNRNPL", "HNRNPR", "HSDL1", "HSP90AA1", "HSP90AB4P", "HSP90B1", "IDH1", "ITM2B", "KDELR1", "KDSR", "KLC4", "KPNA1", "LAMP2", "LBR", "LNPEP", "MBOAT7", "MCL1", "MFSD3", "MGST3", "MIPEP", "MRPL1", "MRPL2", "MRPL3", "MRPS30", "MRPS5", "MSH3", "MSH6", "MTMR6", "MTX1", "NAP1L1", "NEDD4L", "NSA2", "NT5C2", "NUBP2", "NUCB2", "OSBP", "OSBPL8", "P4HA1", "PDK1", "PDK3", "PDS5A", "PDSS1", "PIK3C2A", "PKP2", "POLE", "PPP2R5D", "PPWD1", "PRKCB", "PRMT9", "PSMB2", "PSMB6", "PSME2", "PTBP2", "PXMP2", "PYCR2", "RPL27A", "RPL4", "RPS5", "RPS6KA1", "RSL1D1", "SCARB2", "SCO1", "SCPEP1", "SFXN4", "SLC12A2", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A21", "SLC25A24", "SLC25A4", "SLC25A6", "SPNS1", "SPTBN2", "STT3A", "STX12", "STX3", "STX5", "STX8", "STXBP3", "SUN1", "SYNCRIP", "TAF15", "TAP1", "TAP2", "TFB2M", "THRAP3", "TIMM13", "TIMM17B", "TM7SF2", "TM9SF3", "TMED10", "TMED2", "TMED7", "TSN", "TSPAN6", "TST", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBGCP3", "VAMP7", "VDAC1", "VDAC2", "VPS33B", "XRN2", "YTHDC1", "ZNF326"]} \ No newline at end of file diff --git a/interpro_homologous_superfamily/advanced/idx2term.json b/interpro_homologous_superfamily/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..36d4d2021f59e2b8e2e003e6a93719284f7b2a3c --- /dev/null +++ b/interpro_homologous_superfamily/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier domain superfamily [IPR023395]", "1": "Glycoside hydrolase superfamily [IPR017853]", "2": "Tetratricopeptide-like helical domain superfamily [IPR011990]", "3": "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "4": "RNA-binding domain superfamily [IPR035979]", "5": "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "6": "K Homology domain, type 1 superfamily [IPR036612]"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/advanced/plot_0.png b/interpro_homologous_superfamily/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ecb621c6d34eaed577c603a74584b29479bc7019 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9be716064380ed0cb75f39a177e601bcd138e760c223b7100bbc21b2f627e30e +size 197206 diff --git a/interpro_homologous_superfamily/advanced/plot_1.png b/interpro_homologous_superfamily/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..9cad3e99f7838d1856597d4c886a2faf3dce3208 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e1d10b79a7849f522d0730799c21f7f262b7172a45b54ec237ee00d0a466c173 +size 198322 diff --git a/interpro_homologous_superfamily/advanced/plot_2.png b/interpro_homologous_superfamily/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..f4ba3e746d791ad4fee874f4677f13ccd04195b9 --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d8bcda64445bdf662805131653e7ccf13ccd754ebc85de51cf08ebee8d7abf1b +size 214504 diff --git a/interpro_homologous_superfamily/advanced/plot_3.png b/interpro_homologous_superfamily/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..1e876a6650409b0ccf436b9da817b7602c23535d --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2f00af60c82d1cfa44154065f39638d72c500b22cf86ad51f0c5597d34eec104 +size 216372 diff --git a/interpro_homologous_superfamily/advanced/plot_4.png b/interpro_homologous_superfamily/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..43a90729741ca000f2305161ab0ad45dfd9da2cb --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c7e9451695a77b1d1c156d1130727bc8c2ff3e0890a791fedabe69c416494b49 +size 211779 diff --git a/interpro_homologous_superfamily/advanced/plot_5.png b/interpro_homologous_superfamily/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..df5e33fad8ba0b1885de14d7d66578ca1ba4f0ba --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:02aaf302efcad4e6b43ed01f63abfcf753303bd20d89957bd4d062aa9a8c6377 +size 195248 diff --git a/interpro_homologous_superfamily/advanced/plot_6.png b/interpro_homologous_superfamily/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..8f72fc3abafb9cc34cf32e48609860c5f915587b --- /dev/null +++ b/interpro_homologous_superfamily/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6d762b57d19675882b30f868d1abcaf722a2576bbba171c1cb244f9566299a71 +size 203647 diff --git a/interpro_homologous_superfamily/basic/idx2term.json b/interpro_homologous_superfamily/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9576105d002e03947cf7d73e1ce37078a52049c9 --- /dev/null +++ b/interpro_homologous_superfamily/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial carrier domain superfamily [IPR023395]", "1": "Glycoside hydrolase superfamily [IPR017853]", "2": "Tetratricopeptide-like helical domain superfamily [IPR011990]", "3": "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "4": "RNA-binding domain superfamily [IPR035979]", "5": "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "6": "K Homology domain, type 1 superfamily [IPR036612]", "7": "Immunoglobulin-like domain superfamily [IPR036179]", "8": "Glycosyl hydrolase, all-beta [IPR013780]", "9": "EF-hand domain pair [IPR011992]", "10": "FAD/NAD(P)-binding domain superfamily [IPR036188]", "11": "MFS transporter superfamily [IPR036259]", "12": "Immunoglobulin-like fold [IPR013783]", "13": "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "14": "Alpha/Beta hydrolase fold [IPR029058]", "15": "HAD-like superfamily [IPR036412]", "16": "HAD superfamily [IPR023214]", "17": "WW domain superfamily [IPR036020]", "18": "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "19": "Nucleotide-diphospho-sugar transferases [IPR029044]", "20": "Chaperone J-domain superfamily [IPR036869]", "21": "Immunoglobulin E-set [IPR014756]", "22": "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "23": "Cullin repeat-like-containing domain superfamily [IPR016159]"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/basic/plot_0.png b/interpro_homologous_superfamily/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..5cef3efa42e3e534bb8aaf5a8f330dccee57a106 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f52bb1e1589e691c4855dfdd4e1019550f5de9addce0614a2acd094512413fb1 +size 148891 diff --git a/interpro_homologous_superfamily/basic/plot_1.png b/interpro_homologous_superfamily/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..c202c9d2132f6f6503727bd426969fd8aaa45d97 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:922a26d931f094c0fbe874a6311b0fe33f07ef163389531fc59d15ab69e61acb +size 146808 diff --git a/interpro_homologous_superfamily/basic/plot_10.png b/interpro_homologous_superfamily/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..3b9bdd704db87219d89abbd9378c8eca228a76c6 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4c7cc5f510ec422f7bcdaba8f5c22afa530972a5ba30366375282460c5326bcd +size 149884 diff --git a/interpro_homologous_superfamily/basic/plot_11.png b/interpro_homologous_superfamily/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..8f5ee5e47442eedd6ddfce259e44aa9e45848c74 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:efbde88af0bff6a6b2eacf41c1c5fe603aad6070d74eea792ff769fc1610dd2d +size 138093 diff --git a/interpro_homologous_superfamily/basic/plot_12.png b/interpro_homologous_superfamily/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..55f768accb5560e6b6474771976479e5d0d08080 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f7615cd80a8812c628a10fe7c65e7c0cf86365a28b0c99883ac6b4a4e4233548 +size 139651 diff --git a/interpro_homologous_superfamily/basic/plot_13.png b/interpro_homologous_superfamily/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..704e5745c2510e513c2fe69a4cad6a65e17a7f53 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:923751de5cdb088d570c8dae63baf0b2d83c4d175cc9ffec5bf776a3effbcf28 +size 140393 diff --git a/interpro_homologous_superfamily/basic/plot_14.png b/interpro_homologous_superfamily/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..b1291969ae7cd522a8010d1d21ed31e8e453de75 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:686c0825623519ce05ce25e1b605f53ba22267d6419d03d8ac731a03e9a7bad0 +size 143224 diff --git a/interpro_homologous_superfamily/basic/plot_15.png b/interpro_homologous_superfamily/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..4342cdfccefb47e3dbcdef08d76c91608dc4deba --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:95f6b00b27f6b24d4c3188d7e92548c1ef0bbea74a9af2121bdf5c8704d7d3b9 +size 135444 diff --git a/interpro_homologous_superfamily/basic/plot_16.png b/interpro_homologous_superfamily/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..4901860db6b7759fd6ff8b3eb94a095483933a7c --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f698223055f575f2f44db0feb57c6326d15a247c53fac63053bc92506a52d70f +size 133968 diff --git a/interpro_homologous_superfamily/basic/plot_17.png b/interpro_homologous_superfamily/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..495b295b423ea29abf0b09dd58a750d8793bf95a --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c3332c7990a6be27a5910548f44d49c0e046e102faecea37531ed56260d03de2 +size 136870 diff --git a/interpro_homologous_superfamily/basic/plot_18.png b/interpro_homologous_superfamily/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..532040e156f59fa6297546925aa537a404e79456 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:58099278e750621e2d667da4e8819577a3b56d1048605b01b9f151f7cee58b99 +size 145611 diff --git a/interpro_homologous_superfamily/basic/plot_19.png b/interpro_homologous_superfamily/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..1bb63d9efc2c55302afb9bc031e5563f7f67f1aa --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1148af363d06289f5cad68fb839f967fa70a32786f90b7385d397f56977cd436 +size 157120 diff --git a/interpro_homologous_superfamily/basic/plot_2.png b/interpro_homologous_superfamily/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..860d8ca7ae3dde1e9bc794a33a421a73cdc7ea3a --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:444818b46278cb589a9eda48e4798b8489ee7b8f4ae75f3b464f0af3a0887dbb +size 153844 diff --git a/interpro_homologous_superfamily/basic/plot_20.png b/interpro_homologous_superfamily/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..ec4519f37c9217887a5548be3672820509bf5bd2 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c8c432a4d43119e0e41832b13ebc0929607421ccfd6832e4aa1694e4ee07990f +size 141689 diff --git a/interpro_homologous_superfamily/basic/plot_21.png b/interpro_homologous_superfamily/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..d2754dfd49ececddadefb45955e33131e9e85849 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:16ce7759f2f6d7ee9f585b703930d0a8932ef1858be0ea66dfe06d78c1f2fa91 +size 141422 diff --git a/interpro_homologous_superfamily/basic/plot_22.png b/interpro_homologous_superfamily/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..ca5d20ceccfb4d45e5f7567ac8870dbf9677d4fa --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eb125ba5848b46a7bd7fb24032c51f05ac23455d415b7a2e0d0b01248b6514be +size 157674 diff --git a/interpro_homologous_superfamily/basic/plot_23.png b/interpro_homologous_superfamily/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..df4463ce579dcb45b265042154ea884b19c3da7d --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:62da648ead542eec6b9309c4a524d1ea3804224c339f627992b4f835816ba761 +size 154096 diff --git a/interpro_homologous_superfamily/basic/plot_3.png b/interpro_homologous_superfamily/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..97b5fb0e95a49ad0be9f15009ee7f7515ecb4a29 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ab3eebca28b285a19dae6f7d041ce3bc8cbbb5b754afe58ec658870d9fa6c2c4 +size 153931 diff --git a/interpro_homologous_superfamily/basic/plot_4.png b/interpro_homologous_superfamily/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..31c2a89469db90349c0d866cb2141e827e995b6d --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:390de33345bf931de1b23fedf3b5ded3dfd0f3b4cbebf81dfe71fed1aee4281c +size 151869 diff --git a/interpro_homologous_superfamily/basic/plot_5.png b/interpro_homologous_superfamily/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..f40fa400ecab7e8564f5c61b374a953f50ce5ad6 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:43622ae80638f571e8349bc7233b724da9a36628b97731492fe20ddb44bddeed +size 138875 diff --git a/interpro_homologous_superfamily/basic/plot_6.png b/interpro_homologous_superfamily/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..ba004b93416625e3dc1fc7ce61d8fb78e3c2f016 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:35288892f14b6ef8ca8d7701c0db3fe9fbded6c9916a9d1991a6da4c6f34b47e +size 145492 diff --git a/interpro_homologous_superfamily/basic/plot_7.png b/interpro_homologous_superfamily/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..aced031934accd7f3dbe404669a097479ff10b86 --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bbdd27fb554e8d78bdae0acbcedba948f1d5f11abf6589b698aab2bb1b3537d6 +size 139498 diff --git a/interpro_homologous_superfamily/basic/plot_8.png b/interpro_homologous_superfamily/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..28e251d83bda8a5418781dab1119395b0422e30f --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e4640d1275890a598ccc7accfdfaadd7e0889c13003f2b27ad9ac23c033914d0 +size 137725 diff --git a/interpro_homologous_superfamily/basic/plot_9.png b/interpro_homologous_superfamily/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..3cb7b7d60493f94f37149ea30718fa42e284ba5e --- /dev/null +++ b/interpro_homologous_superfamily/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:35771fa534bac8cee2586b146cffda14a7ebac4d84bcd51446b991dbafd9ce12 +size 137651 diff --git a/interpro_homologous_superfamily/consensus.joblib b/interpro_homologous_superfamily/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..f284ca244746a512e29579b64d6ea01593749062 --- /dev/null +++ b/interpro_homologous_superfamily/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3979116f695568b7334e2f68237b1fc99cd64ec012f60fb13ec8d5a983cd0973 +size 290104 diff --git a/interpro_homologous_superfamily/df_merge.tsv b/interpro_homologous_superfamily/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a2c602f1c87fa0f8b133398a8ad31321785f4faa --- /dev/null +++ b/interpro_homologous_superfamily/df_merge.tsv @@ -0,0 +1,10 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial carrier domain superfamily [IPR023395] 17 20 3.4572099384186736 0.0005457994656994 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 7.343905065826975e-07 3.340697088492455e-05 3.186588308775749e-05 2.348363408710343e-07 1.307589544376179e-07 +Glycoside hydrolase superfamily [IPR017853] 8 16 3.269760452900946 0.0010763859463875 7.094660194174757 15.565533980582524 0.5992585613623983 0.1928722204186086 2.565315823223627 1.245604487832095 1.9386029676344616 0.2695693578719223 3.406846432206643e-07 0.007105321595433 0.0020204438885922 0.0003605515781946 2.110599340548606e-06 +Tetratricopeptide-like helical domain superfamily [IPR011990] 22 94 2.927963176104345 0.0034119045157361 22.856796116504853 85.5631067961165 0.5676132842696584 0.6143258973719493 7.683128498309678 5.891280215778877 0.9202004538980384 0.371378017802006 0.0088738875074687 0.5737510651666717 0.238185905219404 0.0251623965759876 9.455040971600802e-06 +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 45 136 2.824123847910615 0.0047410061363601 41.78155339805825 126.65533980582524 0.1165973051667422 0.543214063567699 13.579176287791377 6.87987395678373 1.6323826073741117 0.3875195330163939 0.0015952553546756 1.0 1.0 0.0039665912482574 1.408603145997782e-07 +RNA-binding domain superfamily [IPR035979] 45 138 2.8004683483833546 0.0051028511426141 42.40291262135922 128.71601941747574 0.0615554024640467 0.5527296641044032 14.098054374547743 6.713949807605091 1.6556654950344032 0.3906506493803742 0.0014516487595054 1.0 1.0 0.0036612636500827 1.1309457923608049e-07 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 3 7 2.234429048658208 0.0254548561425311 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 0.0002477926457577 0.0573151884822011 0.0058956460302812 0.0001472775053537 0.0020033682110678 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 5 8 2.0359384062619497 0.0417565406200859 2.3689320388349513 6.349514563106796 0.6640264147492347 0.3307390797434538 1.7803691733569 2.1393617497725477 1.1694677427725269 0.279101120079799 0.0006394246968973 1.0 1.0 0.0052676758380378 0.0049176108076387 +Zinc finger, RanBP2-type superfamily [IPR036443] 4 9 2.0076734377577776 0.0446780050452488 3.2742718446601944 8.616504854368932 0.6239078002715212 0.4100405386528319 1.463145369641179 0.7330740021954685 1.0299872364022182 0.3121093098016552 0.0024564584457719 1.0 1.0 0.0920739634299925 0.0028394369313259 +K Homology domain, type 1 superfamily [IPR036612] 8 25 1.981565921906832 0.0475278444269569 8.754854368932039 25.199029126213592 0.3274932579192284 0.6117373027860772 4.9138797603502615 1.673377791223898 0.8713427238211133 0.3293224632085303 0.0209197674126672 0.1706778675257841 0.0532804729840314 0.0133642522995781 0.0003978268193634 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3b831a6ce8edcdf097cb3e241a26b501b26c956e --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 1008, + "title": "Average number of proteins per term", + "value": 5.122023809523809 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ac56eb0b1810f4df6c248e60c9e141f8daa0acd8 --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ac000969252b7d105f5ccc62848b53490f312581 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,152 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial carrier domain superfamily [IPR023395] 0.7736349387963399 3.4572099384186736 0.0005457994656994 0.4232325093680943 0.0053937829551473 20 Q6NUK1,O75746,P12236,Q02978,O43808,Q9UBX3,Q9Y619,Q9NZJ7,Q70HW3,Q9Y6C9,Q9H2D1,Q9UJS0,Q9BSK2,Q00325,O43772,Q9BQT8,P12235 17 +Haem oxygenase-like, multi-helical [IPR016084] 0.9830805134189028 3.3362259427928493 0.0008492411343357 0.5753112619461611 0.0067515360468943 2 P30519 1 +Glycoside hydrolase superfamily [IPR017853] 0.8187517432553999 3.269760452900946 0.0010763859463875 0.6622946101010477 0.0077499788139906 16 Q9BTY2,P16278,P06865,P06280,O60502,P54802,P08236,P04062 8 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.9635355892648756 3.2505646286781267 0.0011517608685061 0.6870287832777989 0.0078977888126132 2 O43657 1 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.4163579001920058 2.927963176104345 0.0034119045157361 0.9680977979577018 0.0147790627988055 94 Q9UBV2,O15460,Q13042,Q8IYR2,Q6P2P2,Q9Y262,Q32P28,P13674,P49321,A0AVF1,Q9H7B4,Q6DKK2,Q13535,O75718,Q92791,P42345,Q96DB5,Q9Y6X3,O76024,Q6ZXV5,O00411,O75153 22 +Cytochrome P450 superfamily [IPR036396] 0.8885647607934638 2.9136681642169013 0.0035720938759109 0.9728700487574332 0.0151792732306994 2 Q16850 1 +Nucleotide-binding alpha-beta plait domain superfamily [IPR012677] 0.3866062488959917 2.824123847910615 0.0047410061363601 0.9916900243223028 0.0181708524161637 136 Q14011,P78332,P14866,P52756,P11940,Q14103,Q01844,P98175,Q9BWF3,P98179,P51991,Q99729,Q13151,Q13595,Q01085,P07910,Q15427,Q9P2N5,Q96DH6,O60506,A0AV96,P52597,O43390,P55795,P62995,P31483,Q9UKA9,P23246,P43243,Q96EP5,P31943,P26368,Q9UKM9,P22626,P31942,P23588,Q92804,P38159,Q76FK4,P35637,Q96PK6,O14979,Q9UHX1,Q01081,Q9Y3A4 45 +RNA-binding domain superfamily [IPR035979] 0.3846141119563684 2.8004683483833546 0.0051028511426141 0.9942401420734058 0.0190846803238023 138 Q14011,P78332,P14866,P52756,P11940,Q14103,Q01844,P98175,Q9BWF3,P98179,P51991,Q99729,Q13151,Q13595,Q01085,P07910,Q15427,Q9P2N5,Q96DH6,O60506,A0AV96,P52597,O43390,P55795,P62995,P31483,Q9UKA9,P23246,P43243,Q96EP5,P31943,P26368,Q9UKM9,P22626,P31942,P23588,Q92804,P38159,Q76FK4,P35637,Q96PK6,O14979,Q9UHX1,Q01081,Q9Y3A4 45 +FF domain superfamily [IPR036517] 0.8521003500583442 2.7448571818480834 0.0060537236665587 0.9978030795933088 0.021871517763051 2 O14776 1 +Peptidase S1, PA clan [IPR009003] 0.8471411901983692 2.72164140108297 0.006495858831653 0.998597059835181 0.0230698778360149 2 Q2T9J0 1 +Beta-hexosaminidase-like, domain 2 [IPR029018] 0.895996389638368 2.5420439968881214 0.011020630009338 0.9999859158639488 0.0332598654174035 3 P54802 1 +DCN1-like, PONY binding domain [IPR042460] 0.8636501374980918 2.4003137979678075 0.016381022424311 0.9999999411814308 0.0441927429258851 3 Q92564 1 +Tim10-like domain superfamily [IPR035427] 0.8348409687773409 2.2722218477979466 0.0230731143303388 0.999999999939611 0.0567260957194672 3 Q9Y5J9,Q9Y5L4 2 +Regulatory factor, effector binding domain superfamily [IPR011256] 0.8270961631265819 2.2374895899083596 0.0252543589532678 0.999999999993655 0.0609004636959187 3 Q9Y5Z4 1 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.8162712200602461 2.2344290486582077 0.0254548561425311 0.9999999999948432 0.0612374582140129 7 Q8WUJ1,O15173,O43169 3 +Porin domain superfamily [IPR023614] 0.9049041185993814 2.2203761611980575 0.0263932438774683 0.9999999999980472 0.0623053625959908 4 P21796,P45880 2 +Rhomboid-like superfamily [IPR035952] 0.8228974442750341 2.218607802550331 0.0265134182638571 0.9999999999982756 0.0624428168457195 3 Q9BUN8 1 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.8852889667250365 2.1392055320979617 0.0324190263571333 0.9999999999999962 0.0731059923221262 4 P01889,P04439,P55899 3 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.8852889667250365 2.1392055320979617 0.0324190263571333 0.9999999999999962 0.0731059923221262 4 P01889,P04439,P55899 3 +Ribosomal protein L4 domain superfamily [IPR023574] 0.7182030338389733 2.0959958650913997 0.036082557747944 1.0 0.079936743318522 2 P36578 1 +NAP-like superfamily [IPR037231] 0.8725244092950676 2.0860300423146607 0.036975901825937 1.0 0.0817059916940938 4 P55209 1 +Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330] 0.7100350058343066 2.0549471360705964 0.0398841109949827 1.0 0.0855951223083164 2 Q16706 1 +Glycoside hydrolase family 38, central domain superfamily [IPR037094] 0.7100350058343066 2.0549471360705964 0.0398841109949827 1.0 0.0855951223083164 2 Q16706 1 +Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291] 0.7100350058343066 2.0549471360705964 0.0398841109949827 1.0 0.0855951223083164 2 Q16706 1 +Glycoside hydrolase families 57/38, central domain superfamily [IPR028995] 0.7100350058343066 2.0549471360705964 0.0398841109949827 1.0 0.0855951223083164 2 Q16706 1 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.7276158051171654 2.0359384062619497 0.0417565406200859 1.0 0.0877065000587908 8 P08183,O14678,Q03519,Q03518,Q9NUT2 5 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.7086774498963556 2.0076734377577776 0.0446780050452488 1.0 0.0915354249707538 9 Q92804,P98175,P35637,Q01844 4 +K Homology domain, type 1 superfamily [IPR036612] 0.517707212550956 1.981565921906832 0.0475278444269569 1.0 0.0950556888539138 25 P61978,P51116,Q06787,Q9Y2W6,Q92945,P51114,Q96AE4,Q07666 8 +Immunoglobulin-like domain superfamily [IPR036179] 0.6551366320062484 1.9465294575724377 0.0515911729898876 1.0 0.1009784512112753 12 P10321,P55899,P01889,P35613,P04439 5 +Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784] 0.7624744674642364 1.9429114017248337 0.0520268640837113 1.0 0.1014372901283966 3 Q15118,Q15120 2 +Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352] 0.6846557759626635 1.9263859778204768 0.0540561969835797 1.0 0.10478585876817 2 O14880 1 +Glycosyl hydrolase, all-beta [IPR013780] 0.6792534825314445 1.8523782545481935 0.0639715256489292 1.0 0.1202103150234253 9 P04066,Q16706,Q9BTY2,Q04446,P06280,P10253 6 +Ricin B-like lectins [IPR035992] 0.7414648380507554 1.8453880096287296 0.064981116092508 1.0 0.121523126198976 3 Q8N4A0,Q10472 2 +GTP-binding protein, orthogonal bundle domain superfamily [IPR023179] 0.6683197199533171 1.84285279300938 0.0653505063253483 1.0 0.12179904953045 2 Q9NVN8 1 +EF-hand domain pair [IPR011992] 0.3839115191896439 1.7916437476058704 0.0731900506628806 1.0 0.1298865687820135 57 Q6NUK1,P41208,P80303,Q14257,O43852,Q96AY3,Q9H223,P43304,Q9BRK5,Q9NWM8,O75071,O95202,O95302,Q02818,Q9Y680,Q8NF37,Q8IYU8,Q96D71 18 +Importin-alpha, importin-beta-binding domain superfamily [IPR036975] 0.771941115181525 1.7359038753423546 0.0825808324652697 1.0 0.1425367793236162 5 P52294 1 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.7818459651713275 1.7007684346381375 0.0889864787625718 1.0 0.1525482493072659 4 Q99797,P42892 2 +Bcl-2-like superfamily [IPR036834] 0.7073241902538397 1.6852732552983534 0.0919358632270923 1.0 0.1568043149457006 3 Q07820,Q9BXK5 2 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.7585401459853727 1.6763176677222975 0.0936759860563121 1.0 0.1581299262327635 5 P20020,Q9HD20,P05023,P16615 4 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.7585401459853727 1.6763176677222975 0.0936759860563121 1.0 0.1581299262327635 5 P20020,Q9HD20,P05023,P16615 4 +P-type ATPase, A domain superfamily [IPR008250] 0.7585401459853727 1.6763176677222975 0.0936759860563121 1.0 0.1581299262327635 5 P20020,Q9HD20,P05023,P16615 4 +H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664] 0.6359393232205252 1.6756273598634617 0.0938112062372942 1.0 0.1581299262327635 2 Q9NY12 1 +Riboflavin synthase-like beta-barrel [IPR017938] 0.7037181664963249 1.668253288241207 0.0952654565286086 1.0 0.1587452763272627 3 P16435 1 +Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261] 0.7037181664963249 1.668253288241207 0.0952654565286086 1.0 0.1587452763272627 3 P16435 1 +Ribosomal protein S7 domain superfamily [IPR036823] 0.6338973162193617 1.6650143931256245 0.0959098843225261 1.0 0.1590311927775352 2 P46782 1 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.4955280461005715 1.655475000722887 0.097828183357693 1.0 0.1616570636468108 22 Q9Y2Z2,Q96CU9,Q16134,Q6NUM9,Q8NB78,Q9UHG3,Q14534,O95831 8 +Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940] 0.7354367343067381 1.6539615492896147 0.0981353254762442 1.0 0.1618991948937057 6 Q13315,P42345,Q13535 3 +Ribosomal L18e/L15P superfamily [IPR036227] 0.7000259355253572 1.6508067494018737 0.0987780415246613 1.0 0.161964961809003 3 P46776 1 +Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077] 0.6950431814557438 1.6272316031165177 0.1036879180904453 1.0 0.1678264281029849 3 Q99797 1 +Peptidase M41-like [IPR037219] 0.6266044340723533 1.6270519905504843 0.1037260562580948 1.0 0.1678264281029849 2 Q9Y4W6 1 +Ribosomal protein L37ae/L37e [IPR011331] 0.6181446907818053 1.5829062692998983 0.1134428296040785 1.0 0.1803633631560114 2 P61927 1 +Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930] 0.6839801575722106 1.5747695559190913 0.1153096460129998 1.0 0.1818991559136086 3 P48449,Q6YHK3 2 +ISWI, HAND domain superfamily [IPR036306] 0.6088098016336081 1.534069109771541 0.12501265175457 1.0 0.1893781497777326 2 P28370 1 +MFS transporter superfamily [IPR036259] 0.625579277744731 1.5044770391937683 0.1324585810386787 1.0 0.1975122036789765 8 Q96ES6,Q9H2V7,P53985,Q16625,Q14728 5 +Immunoglobulin-like fold [IPR013783] 0.4057871474746514 1.46983184335344 0.1416073025067363 1.0 0.2089899867156519 34 Q96KP1,P78310,Q04446,P10321,P55899,P01889,P35613,Q8NAT1,P04439,Q6YHK3,P08236,Q8IZA0 12 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.6536389861880477 1.44873725877237 0.1474109711417845 1.0 0.2150365541402588 7 Q10713,Q5JRX3,P31930,O43847 4 +Tubulin/FtsZ, GTPase domain superfamily [IPR036525] 0.645924627519736 1.4104365160283028 0.1584108294219706 1.0 0.2270096258164422 7 P04350,Q9BUK6,Q13885,P68371,Q9BVA1,P07437 6 +Tubulin, C-terminal [IPR023123] 0.6703081321686463 1.3516252116618372 0.1764952408684323 1.0 0.244714171658019 6 P04350,P07437,Q13885,P68371 4 +Tubulin/FtsZ-like, C-terminal domain [IPR037103] 0.6703081321686463 1.3516252116618372 0.1764952408684323 1.0 0.244714171658019 6 P04350,P07437,Q13885,P68371 4 +Tubulin/FtsZ, C-terminal [IPR008280] 0.6703081321686463 1.3516252116618372 0.1764952408684323 1.0 0.244714171658019 6 P04350,P07437,Q13885,P68371 4 +Acyl-CoA N-acyltransferase [IPR016181] 0.5724549895804063 1.332372933498894 0.1827376716900057 1.0 0.2506116640320079 10 Q86UY6,O14929 2 +HSP90, C-terminal domain [IPR037196] 0.6776489007317615 1.3125148002022693 0.189346495665291 1.0 0.2568792296508928 5 Q58FF6,P14625,P07900 3 +SNARE [IPR010989] 0.6835960303560796 1.272178132057863 0.2033098355229203 1.0 0.2714075272275063 4 Q86Y82,Q13190,Q13277 3 +Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035] 0.6821539601346864 1.2658482236576671 0.2055674262821347 1.0 0.2737278278631332 4 Q9NP80,P41247 2 +Alpha/Beta hydrolase fold [IPR029058] 0.4164644552788715 1.256056595739183 0.2090954513412861 1.0 0.2776919828089808 27 P10619,Q9HB40,Q9H3G5,P07099,P42785,Q4J6C6,Q9Y570,P50897,Q8NCC3,Q9NUJ1 10 +DHS-like NAD/FAD-binding domain superfamily [IPR029035] 0.6313547842985536 1.1696518789920312 0.2421410906958234 1.0 0.3145337879141624 6 A1L0T0 1 +HAD-like superfamily [IPR036412] 0.4322135689727235 1.1665454768448562 0.2433939729794296 1.0 0.3153484894129371 22 P49902,Q9HD20,Q969T7,P16615,Q9H857 5 +HAD superfamily [IPR023214] 0.4322135689727235 1.1665454768448562 0.2433939729794296 1.0 0.3153484894129371 22 P49902,Q9HD20,Q969T7,P16615,Q9H857 5 +Ribosomal protein L23/L15e core domain superfamily [IPR012678] 0.5964400350160516 1.1562520530869682 0.2475780739666764 1.0 0.3199470494338587 3 P61313,P62847 2 +LDL receptor-like superfamily [IPR036055] 0.5335472578763285 1.1378538690633924 0.2551815066775331 1.0 0.3280905085853997 2 P14314 1 +Galactose mutarotase-like domain superfamily [IPR011013] 0.6506129597197576 1.127516161479261 0.259524311345755 1.0 0.3324021675178158 4 P10253,O00754,Q16706 3 +Mannose-6-phosphate receptor binding domain superfamily [IPR009011] 0.6464418830958094 1.109261321593644 0.2673174655712089 1.0 0.3398813007483064 4 Q13438 1 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.6182056916386808 1.108319258509603 0.2677239611053128 1.0 0.3398813007483064 6 Q9UIQ6,Q9NZ08,Q6P179 3 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.6182056916386808 1.108319258509603 0.2677239611053128 1.0 0.3398813007483064 6 Q9UIQ6,Q9NZ08,Q6P179 3 +WW domain superfamily [IPR036020] 0.490896909575073 1.1031450508535048 0.2699641794003602 1.0 0.3418641869793506 14 O14776,Q96J02,P46934,Q96PU5,O75400 5 +Histidine kinase/HSP90-like ATPase superfamily [IPR036890] 0.4898177738953082 1.0963645914683655 0.2729192530398268 1.0 0.345172656291274 14 Q15120,Q15118,Q58FF6,P14625,O14874,P07900 6 +Ribonuclease III, endonuclease domain superfamily [IPR036389] 0.5207117852975663 1.070437467090406 0.2844224421672501 1.0 0.3588208031346535 2 Q9UPY3 1 +Six-hairpin glycosidase superfamily [IPR008928] 0.5189614935822806 1.0612641003829153 0.2885698957039619 1.0 0.3635980685869921 2 P35573 1 +Band 7/SPFH domain superfamily [IPR036013] 0.5649527125917582 1.0079050645852845 0.3135000400572669 1.0 0.3915836931570323 7 Q99623,O75477 2 +Zinc-binding ribosomal protein [IPR011332] 0.5611321855850671 0.988048585335242 0.3231288541751105 1.0 0.4031112438224151 3 P61927,P61513 2 +Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068] 0.5005834305717711 0.9653450738565648 0.334372002581162 1.0 0.4140626272749525 2 Q04760 1 +Isoprenoid synthase domain superfamily [IPR008949] 0.604633268454004 0.927494947163266 0.3536696140333917 1.0 0.433517084936477 4 Q5T2R2,P37268 2 +Lamin tail domain superfamily [IPR036415] 0.5481862470660986 0.9269491482522244 0.3539529374034926 1.0 0.433517084936477 3 Q03252 1 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.402381808024967 0.8791872701096906 0.379299745478743 1.0 0.4600892219525547 20 P46976,O60762,Q10472,Q8N4A0,O60512,O43909,O60568 7 +Galactose-binding-like domain superfamily [IPR008979] 0.4878381315449607 0.8594998591370553 0.390064797687887 1.0 0.4714452231047843 10 P16278,P08236,Q08431 3 +DNA/RNA polymerase superfamily [IPR043502] 0.5779546765430025 0.8134545921155331 0.4159574703542952 1.0 0.4991489644251542 4 O00411,Q07864 2 +SAP domain superfamily [IPR036361] 0.4752664123996657 0.7908014584790775 0.4290598587119543 1.0 0.5106166913596811 10 Q9BUJ2,Q1KMD3 2 +DUSP-like superfamily [IPR035927] 0.5513089355050691 0.7482592213820891 0.4543038161324233 1.0 0.5356002884929623 5 Q8NFA0,Q13107 2 +Histidine phosphatase superfamily [IPR029033] 0.526202797779428 0.6889129146097217 0.4908780717901444 1.0 0.5733546887189637 6 Q9NPH0 1 +RGS, subdomain 2 [IPR044926] 0.5426590973351175 0.6666119400609848 0.5050200403417358 1.0 0.588508902502277 4 O43572 1 +Queuine tRNA-ribosyltransferase-like [IPR036511] 0.4407817969661729 0.6627791363391701 0.5074720177491066 1.0 0.590002069078546 2 Q9H974 1 +LEM/LEM-like domain superfamily [IPR011015] 0.5157826317534681 0.6435311418828799 0.5198795142860937 1.0 0.6030363065597035 6 P50402,Q86XL3 2 +WWE domain superfamily [IPR037197] 0.4826378756930422 0.6276674745469044 0.5302217966755711 1.0 0.6143259437344548 3 Q7Z2W4,Q14669 2 +Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236] 0.4194865810968644 0.5611712143948046 0.5746808243327237 1.0 0.6620323096312977 2 O00443 1 +Translin, N-terminal [IPR016068] 0.4174445740956856 0.5516708278029425 0.5811739002541452 1.0 0.6635506331506594 2 Q15631 1 +Translin, C-terminal [IPR016069] 0.4174445740956856 0.5516708278029425 0.5811739002541452 1.0 0.6635506331506594 2 Q15631 1 +Translin superfamily [IPR036081] 0.4174445740956856 0.5516708278029425 0.5811739002541452 1.0 0.6635506331506594 2 Q15631 1 +Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241] 0.4171528588098178 0.5503174416946157 0.5821016632292555 1.0 0.6635506331506594 2 Q96CW5 1 +Thiamin diphosphate-binding fold [IPR029061] 0.4682046465040941 0.5482071590219803 0.5835496669840818 1.0 0.6639030071331314 7 A1L0T0,P11177 2 +Pyridoxal phosphate-dependent transferase, small domain [IPR015422] 0.3983661988039487 0.5398610231870904 0.5892928794413286 1.0 0.6696811978318593 14 P23378,O15269,O15270,O95470 4 +HECT, E3 ligase catalytic domain [IPR035983] 0.4062520109544171 0.5025625076679734 0.6152718946412228 1.0 0.6960651737355248 12 P46934 1 +Beta-grasp domain superfamily [IPR012675] 0.4287240852038994 0.485288362594075 0.6274718093291818 1.0 0.7074849930691446 8 Q9BW92,Q9NTK5 2 +Ribosomal protein L1-like [IPR023674] 0.4482054274876161 0.481996362062799 0.6298085305948673 1.0 0.7085345969192257 3 Q9BYD6,O76021 2 +Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095] 0.4482054274876161 0.481996362062799 0.6298085305948673 1.0 0.7085345969192257 3 Q9BYD6,O76021 2 +L27 domain superfamily [IPR036892] 0.4850464070679298 0.4759318733309287 0.6341229138944651 1.0 0.710433629749658 5 Q9NZW5,Q14168 2 +Sec1-like, domain 3a [IPR043127] 0.484719628215291 0.4746723397713526 0.6350205361155177 1.0 0.710433629749658 5 O00186,Q9H267 2 +Sec1-like superfamily [IPR036045] 0.484719628215291 0.4746723397713526 0.6350205361155177 1.0 0.710433629749658 5 O00186,Q9H267 2 +Sec1-like, domain 1 [IPR043154] 0.484719628215291 0.4746723397713526 0.6350205361155177 1.0 0.710433629749658 5 O00186,Q9H267 2 +Sec1-like, domain 2 [IPR027482] 0.484719628215291 0.4746723397713526 0.6350205361155177 1.0 0.710433629749658 5 O00186,Q9H267 2 +RGS domain superfamily [IPR036305] 0.4796848070122933 0.4553960682671698 0.6488243233472302 1.0 0.7250719711020044 5 O43572 1 +SKP1/BTB/POZ domain superfamily [IPR011333] 0.4788964189461154 0.4524001573506201 0.6509807336300655 1.0 0.7266761677730963 5 Q08380,Q96CX2 2 +GOLD domain superfamily [IPR036598] 0.4639862674139099 0.396960160610377 0.6913968392551779 1.0 0.7649559734327008 5 Q9Y3B3 1 +Homeobox-like domain superfamily [IPR009057] 0.3289659329782864 0.3960027173702199 0.6921030235819674 1.0 0.7649559734327008 22 Q8NB78,Q96G23 2 +50S ribosomal protein L30e-like [IPR029064] 0.4321436065761226 0.3947346881168574 0.6930386998886608 1.0 0.7651511604466267 7 P55769 1 +TGS-like [IPR012676] 0.4306468070842652 0.3887011229172073 0.6974972515971967 1.0 0.7683904148742888 7 Q9NTK5 1 +BRK domain superfamily [IPR037259] 0.4158155821418303 0.3566572161598523 0.7213484383016016 1.0 0.7894888445255314 3 P51532,Q9P2D1 2 +Pyridoxal phosphate-dependent transferase, major domain [IPR015421] 0.3572055605316661 0.3508959028069265 0.725666445381778 1.0 0.7924937995068606 15 P23378,O15269,O15270,O95470 4 +Pyridoxal phosphate-dependent transferase [IPR015424] 0.3572055605316661 0.3508959028069265 0.725666445381778 1.0 0.7924937995068606 15 P23378,O15269,O15270,O95470 4 +PapD-like superfamily [IPR008962] 0.4128975780566182 0.3460491317292284 0.7293057912749696 1.0 0.7956063177545124 3 Q9P0L0,Q8NHP6 2 +Bromo adjacent homology (BAH) domain superfamily [IPR043151] 0.4556333917104558 0.340706066750633 0.7333248710494695 1.0 0.7964711601664609 4 Q86U86,Q13330,O94776 3 +MutS, connector domain superfamily [IPR036678] 0.4111467756054972 0.3397440133503705 0.7340493132883354 1.0 0.7964711601664609 3 P52701,P20585 2 +DNA mismatch repair protein MutS, core domain superfamily [IPR036187] 0.4111467756054972 0.3397440133503705 0.7340493132883354 1.0 0.7964711601664609 3 P52701,P20585 2 +DNA mismatch repair protein MutS, N-terminal [IPR016151] 0.4111467756054972 0.3397440133503705 0.7340493132883354 1.0 0.7964711601664609 3 P52701,P20585 2 +DNA polymerase family B, thumb domain [IPR042087] 0.406298385559022 0.3225228958738723 0.7470565952820782 1.0 0.8071093762533064 3 Q07864 1 +DNA polymerase, palm domain superfamily [IPR023211] 0.406298385559022 0.3225228958738723 0.7470565952820782 1.0 0.8071093762533064 3 Q07864 1 +Oxysterol-binding protein superfamily [IPR037239] 0.4345834970653465 0.3213651941728545 0.7479336563649595 1.0 0.8071917833146457 6 P22059,Q9BZF1 2 +Chaperone J-domain superfamily [IPR036869] 0.3192179233082638 0.2959903871258715 0.767237422618281 1.0 0.823615891372979 19 Q96KC8,Q9UBS4,Q9Y2G8,Q9UGP8,Q9NVH1 5 +GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266] 0.3956813539539102 0.2860897225612754 0.774809402942737 1.0 0.8276575195294413 3 Q8NCN5,Q969Y2 2 +Immunoglobulin E-set [IPR014756] 0.317256779795144 0.2845071423649035 0.7760217612832947 1.0 0.8277565453688477 19 Q96KP1,P61916,Q04446,Q8N3C0,Q6YHK3,Q9UGP8,A6NIH7 7 +G protein alpha subunit, helical insertion [IPR011025] 0.4238178633975547 0.2418142394556731 0.8089241048159495 1.0 0.8592154875178895 4 Q14344,P63096,P04899 3 +Concanavalin A-like lectin/glucanase domain superfamily [IPR013320] 0.3012731482622227 0.2328841377584417 0.8158513760628492 1.0 0.8628205840014943 23 Q00839,O94813,O14786,P27824,Q1KMD3,P49257,Q9BUJ2 7 +Dynein heavy chain, AAA1 domain, small subdomain [IPR043157] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.882017286384693 2 Q8NCM8 1 +Dynein heavy chain, linker, subdomain 3 [IPR042228] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.882017286384693 2 Q8NCM8 1 +Dynein heavy chain, C-terminal domain, barrel region [IPR043160] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.882017286384693 2 Q8NCM8 1 +Dynein heavy chain AAA lid domain superfamily [IPR042219] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.882017286384693 2 Q8NCM8 1 +Dynein heavy chain, domain 2, N-terminal [IPR042222] 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.882017286384693 2 Q8NCM8 1 +Cyclic nucleotide-binding-like [IPR018490] 0.383410750521617 0.1483238243902465 0.882087214167407 1.0 0.915699188342684 5 Q8IY17,Q9Y4G8,Q6P4Q7 3 +Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100] 0.3383190147108065 0.1429810726390637 0.886305129440168 1.0 0.9181866089164332 9 O15254,Q15067 2 +Acyl-CoA dehydrogenase-like, C-terminal [IPR036250] 0.3383190147108065 0.1429810726390637 0.886305129440168 1.0 0.9181866089164332 9 O15254,Q15067 2 +NTF2-like domain superfamily [IPR032710] 0.333420363798829 0.1200699179873922 0.9044277619287177 1.0 0.9319555813545066 8 Q9BRJ2 1 +SCP2 sterol-binding domain superfamily [IPR036527] 0.336154070615709 0.1190982918785653 0.9051974839961204 1.0 0.9319555813545066 3 P51659,Q6YN16 2 +NUDIX hydrolase-like domain superfamily [IPR015797] 0.3275527684030616 0.1104002201229469 0.912091978564286 1.0 0.9362410533531572 9 A8MXV4,Q9H2W6 2 +Histone deacetylase domain superfamily [IPR037138] 0.2935665431597365 0.0426507271847397 0.9659799578069131 1.0 0.9819629990859646 3 Q9UBN7 1 +RuvA domain 2-like [IPR010994] 0.330122591943965 0.0421535581981057 0.9663762848147588 1.0 0.9819629990859646 4 Q14807,Q96QE5,Q8N5C6 3 +AP-2 complex subunit mu, C-terminal superfamily [IPR036168] 0.3266199649737378 0.037520983222465 0.9700696097332376 1.0 0.9847232292156126 4 Q96CW1,Q9Y2T2,Q9BXS5 3 +HotDog domain superfamily [IPR029069] 0.3124379651829576 0.0193420817588803 0.984568213810148 1.0 0.998435371751136 5 O14734 1 +Cullin repeat-like-containing domain superfamily [IPR016159] 0.2859649122806999 0.0133037528676966 0.9893854540981823 1.0 1.0 10 Q9UID3,Q8IYI6,Q96MW5,Q13619,Q9UPT5,Q93034,Q13617,Q13616,Q13620 9 +Proteasome activator superfamily [IPR036252] 0.2646134551763458 0.0102923383576813 0.9917880471151816 1.0 1.0 3 Q9UL46 1 +Proteasome activator PA28, C-terminal domain superfamily [IPR036997] 0.2646134551763458 0.0102923383576813 0.9917880471151816 1.0 1.0 3 Q9UL46 1 +Proteasome activator PA28, N-terminal domain superfamily [IPR036996] 0.2646134551763458 0.0102923383576813 0.9917880471151816 1.0 1.0 3 Q9UL46 1 +Zinc finger, Sec23/Sec24-type superfamily [IPR036174] 0.2584459082484579 0.0051833611424202 0.9958642946905653 1.0 1.0 3 O95487 1 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3d324d77a8c59edfca0b89fe750d3465e60fb7ba --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "AAR2, C-terminal domain superfamily [IPR038514]", "AAR2, N-terminal domain superfamily [IPR038516]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adaptor protein Cbl, N-terminal domain superfamily [IPR036537]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha-macroglobulin, receptor-binding domain superfamily [IPR036595]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin, N-terminal [IPR014753]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "Atg6/Beclin C-terminal domain superfamily [IPR038274]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Bacterial exopeptidase dimerisation domain [IPR036264]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Bcr-Abl oncoprotein oligomerisation domain superfamily [IPR036481]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CBP/p300, atypical RING domain superfamily [IPR038547]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CGI121/TPRKB superfamily [IPR036504]", "CH domain superfamily [IPR036872]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Calycin [IPR012674]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Caspase-like domain superfamily [IPR029030]", "Catenin binding domain superfamily [IPR027397]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chondroitin AC/alginate lyase [IPR008929]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coactivator CBP, KIX domain superfamily [IPR036529]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Copper homeostasis (CutC) domain superfamily [IPR036822]", "Core-binding factor, beta subunit superfamily [IPR036552]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit VIb superfamily [IPR036549]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHBP synthase RibB-like alpha/beta domain superfamily [IPR017945]", "DHH phosphoesterase superfamily [IPR038763]", "DHHA2 domain superfamily [IPR038222]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "DhaL domain superfamily [IPR036117]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 2 [IPR042264]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3 ubiquitin-protein ligase ELL-like [IPR042065]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "EYA domain superfamily [IPR038102]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD-linked oxidoreductase-like [IPR029041]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FCS-type zinc finger superfamily [IPR038603]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Folliculin, DENN domain, C-terminal superfamily [IPR044886]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GBBH-like, N-terminal domain superfamily [IPR038492]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP cyclohydrolase 1 type 2/Nif3 superfamily [IPR036069]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GTPase HflX, N-terminal domain superfamily [IPR042108]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Heavy metal-associated domain superfamily [IPR036163]", "Helix hairpin bin domain superfamily [IPR029012]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "HesB-like domain superfamily [IPR035903]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MAP kinase activated protein kinase, C-terminal [IPR027442]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTERF superfamily, mitochondrial/chloroplastic [IPR038538]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Mog1/PsbP, alpha/beta/alpha sandwich [IPR016123]", "Molybdopterin biosynthesis MoaE subunit superfamily [IPR036563]", "Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily [IPR036522]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Ndc80 domain superfamily [IPR038273]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Notch-like domain superfamily [IPR035993]", "Nuclear receptor coactivator, CREB-bp-like, interlocking domain superfamily [IPR037073]", "Nuclear receptor coactivator, interlocking [IPR009110]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "Nuf2, N-terminal domain superfamily [IPR038275]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PD-(D/E)XK endonuclease-like domain superfamily [IPR011604]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLAT/LH2 domain superfamily [IPR036392]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosducin, N-terminal domain superfamily [IPR023196]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 1/3 [IPR024066]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RNase P subunit Pop5/Rpp14/Rnp2-like domain superfamily [IPR038085]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RUN domain superfamily [IPR037213]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Rap/Ran-GAP superfamily [IPR035974]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rel homology domain (RHD), DNA-binding domain superfamily [IPR037059]", "Restriction endonuclease type II-like [IPR011335]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rubisco LSMT, substrate-binding domain superfamily [IPR036464]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SATB, CUTL domain superfamily [IPR038216]", "SATB, ULD domain superfamily [IPR038224]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Secretoglobin superfamily [IPR035960]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Set2 Rpb1 interacting domain superfamily [IPR038190]", "Seven-hairpin glycosidases [IPR036026]", "Sialidase superfamily [IPR036278]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Smaug, PHAT domain superfamily [IPR037093]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Soluble quinoprotein glucose/sorbosone dehydrogenase [IPR011041]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAP42/TAP46-like superfamily [IPR038511]", "TAZ domain superfamily [IPR035898]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Taurine dioxygenase TauD-like superfamily [IPR042098]", "Tautomerase/MIF superfamily [IPR014347]", "Telomere repeat-binding factor, dimerisation domain superfamily [IPR036507]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonine synthase, N-terminal domain superfamily [IPR037158]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription factor EnY2 superfamily [IPR038212]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "Tryptophan synthase beta subunit-like PLP-dependent enzyme [IPR036052]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ubiquitin-protein ligase E3A, N-terminal zinc-binding domain superfamily [IPR042556]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS28, C-terminal domain superfamily [IPR037206]", "VPS28, N-terminal domain superfamily [IPR038358]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "XRCC4, N-terminal domain superfamily [IPR009089]", "XRCC4-like, N-terminal domain superfamily [IPR038051]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA uridine 5-carboxymethylaminomethyl modification enzyme, C-terminal subdomain [IPR044920]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AGTPBP1", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP10", "AKAP13", "AKR1A1", "AKR1B1", "AKR7A2", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APIP", "APMAP", "APP", "APRT", "AQR", "ARAP1", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "AS3MT", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATM", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5O", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATR", "ATXN10", "AURKA", "AURKB", "B4GALT3", "BABAM1", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAS3", "BCAT1", "BCAT2", "BCKDHB", "BCKDK", "BCL2L13", "BCR", "BCS1L", "BDH2", "BECN1", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C1QBP", "C2CD2L", "C2CD5", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPV", "CEP170", "CEP97", "CERS2", "CETN2", "CFL1", "CFL2", "CHAC2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHM", "CHORDC1", "CHRAC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "CNP", "COA7", "COASY", "COG8", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DENND5B", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGKE", "DHCR24", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2A", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DR1", "DRG1", "DRG2", "DSC2", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD2", "EFL1", "EFR3A", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELF2", "ELMO2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETHE1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EYA4", "EZR", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAM120B", "FAM129B", "FAR1", "FAR2", "FARP2", "FARSA", "FARSB", "FASN", "FBL", "FBXL18", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FH", "FHOD1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTB", "FOCAD", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FSD1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "FYCO1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNB1L", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNPNAT1", "GNS", "GOLPH3", "GORASP2", "GOT1", "GOT2", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP6", "GTPBP8", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMCES", "HMG20A", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HP1BP3", "HPRT1", "HPS5", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90AB4P", "HSP90B1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPDH2", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS14", "INTS4", "INTS6", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "ITSN2", "IVD", "JUP", "KARS", "KAT7", "KATNB1", "KCTD10", "KCTD12", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA1468", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC14", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A2", "MAN2A1", "MAN2B1", "MAP1A", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCRS1", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED16", "MED21", "MEPCE", "METAP2", "METTL13", "METTL25", "METTL7B", "MFGE8", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU2", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMS19", "MOCS1", "MOCS2", "MOCS3", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPDZ", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL4", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFR", "MTIF2", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCKIPSD", "NCL", "NCOA5", "NCOR1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEK9", "NELFE", "NENF", "NET1", "NEU1", "NF1", "NFATC2IP", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP37", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OXCT1", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PARS2", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXP", "PEBP1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHLDB2", "PI4KA", "PICALM", "PIK3C2A", "PIK3R2", "PIK3R4", "PIP4K2C", "PIR", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLEC", "PLEKHA5", "PLEKHA7", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POR", "POU2F1", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF18", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRUNE1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB36", "RAB3B", "RAB4A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAF1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RASAL2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBBP9", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REL", "RELA", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RGS10", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMC1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRM1", "RRM2", "RRP12", "RRP7A", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTF1", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SATB2", "SBDS", "SBNO1", "SCAF11", "SCCPDH", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL1", "SCYL2", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFMBT1", "SFPQ", "SFSWAP", "SGK3", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SIN3A", "SIPA1", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMS", "SMU1", "SMYD3", "SMYD4", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNX1", "SNX12", "SNX14", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX12", "STX3", "STX5", "STX7", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAOK1", "TAP1", "TAP2", "TAPBP", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFB2M", "TFCP2", "TFRC", "THADA", "THNSL1", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TNRC6A", "TOE1", "TOM1", "TOM1L2", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TONSL", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPMT", "TPP1", "TPP2", "TPRKB", "TPT1", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC28", "TTC37", "TTC38", "TTC4", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR2", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP32", "USP34", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIPAS39", "VIRMA", "VKORC1L1", "VPS16", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VRK3", "WAPL", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR35", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR47", "WDR48", "WDR5", "WDR6", "WDR61", "WDR62", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WNK1", "WRAP53", "WRAP73", "WWP2", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO6", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZFR", "ZFYVE16", "ZMAT2", "ZNF281", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZPR1", "ZRANB2"], "leading_proteins": ["ABCB1", "ABCB8", "ABCD4", "ABHD10", "ACOT8", "ACOX1", "ACOX3", "ACP6", "AFG3L2", "AGL", "AIFM1", "AKAP10", "ANKLE2", "AP1M1", "AP2M1", "AP3M1", "ASCC3", "ATM", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATR", "B4GALT3", "BCKDK", "BCL2L13", "BSG", "CALU", "CANX", "CD109", "CDC16", "CERS2", "CETN2", "CHD7", "CIRBP", "CLUH", "CNNM4", "COG8", "CPVL", "CRTAP", "CTSA", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5D2", "CYP51A1", "DAZAP1", "DCUN1D4", "DERL1", "DICER1", "DNAJB11", "DNAJC1", "DNAJC11", "DNAJC16", "DPM1", "DYNC2H1", "ECE1", "EFCAB14", "EHD4", "EIF3L", "EIF4B", "EMD", "EPHX1", "ERAP1", "ERAP2", "ERLIN1", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOC8", "EXTL3", "FCGRT", "FDFT1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "FMR1", "FOXRED1", "FUBP1", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "GAA", "GALNT1", "GALNT4", "GAR1", "GBA", "GBE1", "GLA", "GLB1", "GLDC", "GLO1", "GNA13", "GNAI1", "GNAI2", "GNL3L", "GPD2", "GTPBP3", "GUSB", "GYG1", "HAT1", "HDAC6", "HEBP2", "HEXA", "HLA-A", "HLA-B", "HLA-C", "HMOX2", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB4P", "HSP90B1", "ILVBL", "ITCH", "KCTD12", "KDM1B", "KHDRBS1", "KHSRP", "KIAA0319L", "KIF22", "KPNA1", "LETM1", "LGALS3BP", "LMAN1", "LMNB2", "LNPEP", "LPCAT1", "LSS", "MAN2A1", "MAN2B1", "MATR3", "MAU2", "MCL1", "MFGE8", "MFSD10", "MFSD3", "MGEA5", "MGST3", "MICU2", "MIPEP", "MOSPD2", "MPP2", "MPP6", "MRPL1", "MRPL45", "MRPL46", "MSH3", "MSH6", "MSI2", "MSTO1", "MTA1", "MTA2", "MTCH1", "MTCH2", "MTO1", "MTOR", "NAA40", "NAGLU", "NAP1L1", "NASP", "NEDD4", "NEDD4L", "NOL8", "NPC2", "NRDC", "NRP1", "NT5C2", "NT5C3B", "NT5DC2", "NUCB1", "NUCB2", "NUDT19", "OCLN", "OLA1", "OS9", "OSBP", "OSBPL8", "P3H1", "P3H4", "P4HA1", "P4HA2", "PABPC1", "PBRM1", "PCYOX1", "PDHB", "PDK1", "PDK3", "PDPR", "PDSS1", "PGRMC2", "PHB2", "PIK3C2A", "PITRM1", "PLA2G15", "PLOD3", "PMPCA", "PNPLA4", "PNPLA6", "PNPLA8", "POLE", "POLRMT", "POMGNT2", "POR", "PPME1", "PPT1", "PRCP", "PREPL", "PRKCSH", "PRMT9", "PRPF40A", "PSME2", "PTBP2", "PUF60", "QTRT2", "RALY", "RAPGEF2", "RBM10", "RBM14", "RBM27", "RBM3", "RBM4", "RBM47", "RBM5", "RBM6", "RBMX", "RCN2", "REPS1", "RETSAT", "RMDN1", "RPL15", "RPL27A", "RPL37", "RPL37A", "RPL4", "RPS24", "RPS5", "RRP7A", "RSL1D1", "SCPEP1", "SDF4", "SEC24B", "SEC63", "SEL1L", "SF3B4", "SFPQ", "SGPL1", "SLC16A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A6", "SLIT2", "SMARCA1", "SMARCA4", "SMYD3", "SMYD4", "SNU13", "SPNS1", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "STX12", "STX3", "STX5", "STXBP3", "SYNCRIP", "TAF15", "TAP1", "TAP2", "TARS2", "TCERG1", "TDRKH", "TEFM", "TIA1", "TIAL1", "TIMM13", "TIMM8B", "TMED7", "TMTC3", "TRA2A", "TRA2B", "TRIP12", "TSN", "TSPAN6", "TTC19", "TTC26", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBGCP3", "TYSND1", "U2AF1", "U2AF2", "UNC119B", "UQCRC1", "USP32", "USP4", "VAPA", "VDAC1", "VDAC2", "VPS33B", "VPS51", "WFS1", "ZC3HAV1"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..566efd43b4e23e4230ef289ce669cf2d9020df65 --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:43a9250b484f20c02d3d2512c61bb6e1f07a1ce6f94f020a94fe2ca4e04ad54e +size 76136 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..aaa00009cb659b91a21206b613845d12b191f78c --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.5 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..232ce01db59ed1c301e70b5b179666079ef96c6c --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ce9332d4b42f4364e1ae4a47b1ecef7dca98bc29 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.7585401459853727 1.6763176677222975 0.0936759860563121 0.325263896518173 0.1752465707530068 5 P20020,Q9HD20,P05023,P16615 4 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..75f6ffa1b9492676287afb170a4fcb67271e8a76 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "EIF5A", "FASN", "LRP1", "NOTCH2", "SLIT2"], "leading_proteins": ["ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8911d98854d4d923c63ac00c165d1c7e56a226ad --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a245f62b5835500814fce428bf3e69f1a017829d4b1e1f76ff8bc5f83a78b800 +size 187213 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c65f5c317beeefea517b31d875c5b7123c646372 --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]", "1": "HAT (Half-A-TPR) repeat [IPR003107]", "2": "Tetratricopeptide repeat [IPR019734]", "3": "HEAT, type 2 [IPR021133]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..350943c79fe41ea54df3a35ae6b6237fb978117a --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d78e417b236166982b39b8f11c3db0e08cdf2575b268580e2882e90a5f143742 +size 149436 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..2f53d5b00ac30f7ddbedd5e0aa8212fa7a224ae8 --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f7eceb53da929fe0a8861ceb5a6feef8788c0541f85d0efb2d7ab832dd6fc4ee +size 136236 diff --git a/interpro_repeat/basic/plot_2.png b/interpro_repeat/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..c8a06a3c509702659a5be5eb349cfb97dda77a2c --- /dev/null +++ b/interpro_repeat/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0c8bb177f8864adf0fe241ffafc609772aeadaeb139a8a9fe8982187872c4bfe +size 148116 diff --git a/interpro_repeat/basic/plot_3.png b/interpro_repeat/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..a72cd8b5c54cc5431b22e9cd8e5df5f5a1478f3b --- /dev/null +++ b/interpro_repeat/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e7233b47517ec0b5edcba29828ac6708a75a6cd7786a364aab817f5b77e8f72f +size 141717 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..366e07c4bdd88d8ad6bad53ec2b508e291b3c10d --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:978c96193f76d25c60527c7ca5b755ee5f0d8a5c3032b3d6c76dc382559dea68 +size 91708 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..bb30ede51a290104e5f3c7937cd7c5bcff8b3bb0 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 17 20 3.4572099384186736 0.0005457994656994 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 7.343905065826975e-07 3.340697088492455e-05 3.186588308775749e-05 2.348363408710343e-07 1.307589544376179e-07 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..18e4f5636bb14bb97c3e0b7a7a2a20cd44202d23 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 79, + "title": "Average number of proteins per term", + "value": 5.886075949367089 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3dc99f62a966856aa1246457664597ac3a1fee39 --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..01da10776850bd6d7ffb5da2016c98350d93b040 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,11 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.7736349387963399 3.4572099384186736 0.0005457994656994 0.0422130623238391 0.0053897697237819 20 Q6NUK1,O75746,P12236,Q02978,O43808,Q9UBX3,Q9Y619,Q9NZJ7,Q70HW3,Q9Y6C9,Q9H2D1,Q9UJS0,Q9BSK2,Q00325,O43772,Q9BQT8,P12235 17 +Atypical Arm repeat [IPR032413] 0.771941115181525 1.7359038753423546 0.0825808324652697 0.998896284974378 0.138806080101198 5 P52294 1 +Low-density lipoprotein (LDL) receptor class A repeat [IPR002172] 0.5335472578763285 1.1378538690633924 0.2551815066775331 0.9999999999220196 0.3571980424183289 2 P14314 1 +Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547] 0.4730084622118606 0.5858708018689172 0.5579623399315543 1.0 0.6557221778330924 3 Q9P253,Q8WUH2 2 +Kinesin light chain repeat [IPR015792] 0.4707763859444 0.5762901348764561 0.5644190897803834 1.0 0.6557221778330924 3 Q9NSK0 1 +HAT (Half-A-TPR) repeat [IPR003107] 0.4297399941571718 0.3850604721141434 0.7001926129006248 1.0 0.7902173774164195 7 Q9BZJ0,Q12996,Q9HCS7,Q14690,O94906,Q15020 6 +Tetratricopeptide repeat [IPR019734] 0.2675515303983611 0.3674581714870305 0.7132772871064681 1.0 0.7910934966266733 52 Q9Y6X3,A0AVF1,Q6ZXV5,O15460,Q13042,Q6DKK2,Q6P2P2,P13674,P49321 9 +HEAT repeat [IPR000357] 0.4322285817831363 0.3131397948860347 0.754174456371772 1.0 0.8161613979913697 6 Q8TEX9,P30154,P30153,Q6PJG6 4 +HEAT, type 2 [IPR021133] 0.3513109550810023 0.2896208226748223 0.7721063352482678 1.0 0.8242756822245021 14 P30154,Q13535,Q9BU89,Q9NXF1,P30153 5 +Pentatricopeptide repeat [IPR002885] 0.418563922942213 0.226849575946552 0.8205407124087205 1.0 0.8643028837371857 4 P42704,O75127,Q96EY7 3 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..00806ab8d613e57a6526f52cbf55a8417c7edee6 --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Huntingtin, middle-repeat [IPR024613]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "MORN motif [IPR003409]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Nebulin repeat [IPR000900]", "Neuraxin/MAP1B repeat [IPR000102]", "Opioid growth factor receptor repeat [IPR006770]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "YD repeat [IPR006530]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "ACAP2", "ACTN1", "ACTN2", "ACTN4", "AGAP3", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD13A", "ANKRD17", "ANKS1A", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC1", "ARMC6", "ARMC8", "ARMCX3", "ARPC1A", "ARPC1B", "ARVCF", "ASPH", "ATR", "BARD1", "BIRC6", "BOP1", "BRAT1", "BUB3", "CAST", "CDC16", "CDC23", "CDC27", "CDC40", "CEP97", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN2", "CNN3", "CNOT10", "COA7", "COPA", "COPB2", "CORO1B", "CORO1C", "CORO7", "CRNKL1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DTL", "DYNC1I2", "EDC4", "EHMT1", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "FNTB", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GMPPB", "GNB1", "GNB1L", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HTT", "HUWE1", "IFIT5", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "ITGA6", "ITGAV", "JUP", "KAT7", "KATNB1", "KDELC2", "KDM2A", "KIAA1468", "KIDINS220", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "LARP1", "LASP1", "LLGL1", "LRBA", "LRCH2", "LRP1", "LRPPRC", "LRRC1", "LRRC14", "LRRC40", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MED16", "MKI67", "MRPS27", "MTCH1", "MTCH2", "MTPN", "MYCBP2", "NAA15", "NASP", "NEK9", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NOL10", "NOP2", "NOP9", "NOTCH2", "NUP214", "NUP37", "NXF1", "OGFR", "OGT", "OSBPL1A", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PHIP", "PIK3R4", "PKP2", "PLAA", "PLEC", "PLRG1", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRMT9", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM1", "PUM3", "PWP1", "PWP2", "RABGGTA", "RACK1", "RAE1", "RAI14", "RANBP2", "RANGAP1", "RAP1GDS1", "RBBP4", "RBBP5", "RBBP7", "RCC1", "RCC2", "RNH1", "RPAP3", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC31A", "SEL1L", "SETD7", "SFMBT1", "SGTA", "SHCBP1", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL2", "TBL3", "TENM3", "TEX10", "TGFBRAP1", "THOC3", "THOC6", "TMTC3", "TOMM34", "TOMM70", "TONSL", "TPBG", "TRIO", "TTC1", "TTC19", "TTC26", "TTC27", "TTC28", "TTC37", "TTC4", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR35", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR47", "WDR48", "WDR5", "WDR6", "WDR61", "WDR62", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WRAP53", "WRAP73", "XAB2", "XPO1", "YTHDC2", "ZC3H7B"], "leading_proteins": ["ATR", "BRAT1", "CDC16", "CRNKL1", "CSTF3", "DOHH", "IPO4", "KLC4", "KPNA1", "LRPPRC", "MAU2", "MTCH1", "MTCH2", "NASP", "P4HA1", "P4HA2", "PDCD11", "PPP2R1A", "PPP2R1B", "PRKCSH", "PRMT9", "PRPF6", "PTCD1", "PTCD3", "SART3", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A6", "TEX10", "TGFBRAP1", "TMTC3", "TTC19", "TTC26", "VPS18", "XAB2"]} \ No newline at end of file diff --git a/msigdb_gobp/advanced/idx2term.json b/msigdb_gobp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..cb1b8e01cc44f22fd6bb01d2b986c4fa409ba070 --- /dev/null +++ b/msigdb_gobp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transmembrane transport", "1": "Mitochondrion organization", "2": "Anion transport", "3": "Organic anion transport", "4": "Membrane lipid metabolic process", "5": "Anion transmembrane transport", "6": "Ion transmembrane transport", "7": "Ion transport", "8": "Lipid metabolic process", "9": "Mitochondrial transport"} \ No newline at end of file diff --git a/msigdb_gobp/advanced/plot_0.png b/msigdb_gobp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d5b97fb4e0de4b34a8ab6c8638850a4f636257d9 --- /dev/null +++ b/msigdb_gobp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9093627a932bc50471e853474447d4ee9f5408900d7179accc202586452d5e64 +size 221270 diff --git a/msigdb_gobp/advanced/plot_1.png b/msigdb_gobp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..83582f162b5934b9044fb109763231c947e65f5d --- /dev/null +++ b/msigdb_gobp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b597ee56539f1a70eac0f28b5baed7e05dd2decfc36aa0178c09dd72d3efc17a +size 226472 diff --git a/msigdb_gobp/advanced/plot_2.png b/msigdb_gobp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..0c5b39649c51f6ae34002040938695abd18ddbf9 --- /dev/null +++ b/msigdb_gobp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1ff61a5f33a9f1957d9ff3c61d7d70e2a92bc9e54dcbbec30bdcaba3abee9bdf +size 207130 diff --git a/msigdb_gobp/advanced/plot_3.png b/msigdb_gobp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..f5d33680ca2a1cbe91f70ed4184256a2069ac598 --- /dev/null +++ b/msigdb_gobp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d725fc68a5687baa66c4c857fb26f53d754e70eaa11a360f413cf633573d2d44 +size 204229 diff --git a/msigdb_gobp/advanced/plot_4.png b/msigdb_gobp/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..6b2dfdd8a70500bb7de311de04b57766b4e7c14b --- /dev/null +++ b/msigdb_gobp/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c986f696d355abd2c2387cd988af4d36a4befa809be92ff06de907911b84b998 +size 204648 diff --git a/msigdb_gobp/advanced/plot_5.png b/msigdb_gobp/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..b13fb36e42c4e63cc73acce23bb65fc8ffb41d1d --- /dev/null +++ b/msigdb_gobp/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d5c385c878e29543f38afeb7a59766740d64e7212407aac0fabfd4d15e2eac9f +size 204053 diff --git a/msigdb_gobp/advanced/plot_6.png b/msigdb_gobp/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..54799140cf5e4130623faf886e5ca1144e604348 --- /dev/null +++ b/msigdb_gobp/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3a6aaa1e8a4c5f66ded135d301e60c7417c020d3b579b6568c72054c7101166e +size 220103 diff --git a/msigdb_gobp/advanced/plot_7.png b/msigdb_gobp/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..fdbae0746143a1412b01a28ef5cb36baa4a6153d --- /dev/null +++ b/msigdb_gobp/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6b42f35894fbc9842b87b78ea9ac02fbb021b06df295f3bb7f0d77bdc7ef8851 +size 221991 diff --git a/msigdb_gobp/advanced/plot_8.png b/msigdb_gobp/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..609011ba9c21dd7735788e5feaa043fa6e4eda0d --- /dev/null +++ b/msigdb_gobp/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:16841eed48d82c83efbb3adda39f52a6b752381e66c6b9d518a857ea5286642b +size 231091 diff --git a/msigdb_gobp/advanced/plot_9.png b/msigdb_gobp/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..ba127c123faf3cf15d1e5db8575eea9a1511616b --- /dev/null +++ b/msigdb_gobp/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bd8b86adaf3af7ba8de1dc183f712453055cfdb5066d262cd5cd4eb89b56b9dc +size 216413 diff --git a/msigdb_gobp/basic/idx2term.json b/msigdb_gobp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6037b4076f79aa5e9caef5eefe8155b0c0c3dde3 --- /dev/null +++ b/msigdb_gobp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transmembrane transport", "1": "Mitochondrion organization", "2": "Anion transport", "3": "Organic anion transport", "4": "Membrane lipid metabolic process", "5": "Anion transmembrane transport", "6": "Ion transmembrane transport", "7": "Ion transport", "8": "Lipid metabolic process", "9": "Mitochondrial transport", "10": "Sphingolipid metabolic process", "11": "Lipid localization", "12": "Organic acid transport", "13": "Secondary alcohol metabolic process", "14": "Mitochondrial transmembrane transport", "15": "Steroid metabolic process", "16": "Mitochondrial respiratory chain complex assembly", "17": "Lipid biosynthetic process", "18": "Cellular lipid metabolic process", "19": "Sterol metabolic process", "20": "Carboxylic acid transport", "21": "Cation transmembrane transport", "22": "Mitochondrial membrane organization", "23": "Organic acid transmembrane transport", "24": "Membrane organization", "25": "Inorganic ion transmembrane transport", "26": "Vacuole organization", "27": "Glycoprotein biosynthetic process", "28": "Protein targeting to mitochondrion", "29": "Protein localization to mitochondrion", "30": "Protein targeting", "31": "Membrane lipid biosynthetic process", "32": "Cation transport", "33": "Ceramide metabolic process", "34": "Lytic vacuole organization", "35": "Glycosylation", "36": "Carbohydrate derivative catabolic process", "37": "Protein insertion into membrane", "38": "Glycoprotein metabolic process", "39": "Hormone metabolic process", "40": "Liposaccharide metabolic process", "41": "Alcohol metabolic process", "42": "Regulation of hormone levels", "43": "Lipid catabolic process", "44": "Organophosphate ester transport", "45": "Sphingolipid biosynthetic process", "46": "Meiotic cell cycle process", "47": "Alternative mrna splicing via spliceosome", "48": "Response to oxidative stress", "49": "Steroid biosynthetic process"} \ No newline at end of file diff --git a/msigdb_gobp/basic/plot_0.png b/msigdb_gobp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..0c599b2bd18441e10e96e43ce3369fac92f798f9 --- /dev/null +++ b/msigdb_gobp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a13f6a2e3b2875d690a31639fba9a586543adc1db10943d7c781b8107657de97 +size 138884 diff --git a/msigdb_gobp/basic/plot_1.png b/msigdb_gobp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..7a0aff38377755dfc7836906375e7c2c3ad7175b --- /dev/null +++ b/msigdb_gobp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0efd95fd5c8cf7460540d10007de2b323b429ac5d9c209bbabe705ccdeab5b6b +size 150161 diff --git a/msigdb_gobp/basic/plot_10.png b/msigdb_gobp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..a8c1774d2d10be95722cadf83cf1b766bd6a5748 --- /dev/null +++ b/msigdb_gobp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5cdac0d3455deb15e3ca1a75de2df48b6fcd5bb55e5d71938445af5382d0d34a +size 146515 diff --git a/msigdb_gobp/basic/plot_11.png b/msigdb_gobp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..7d7ea6bbdcecfa3c639d5e30f796e9cc3ccb35f5 --- /dev/null +++ b/msigdb_gobp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b5fd1c4a907df2129f0b91b0cb2211b84e8c721e8a9fce76cd1da0294bcaddf6 +size 136195 diff --git a/msigdb_gobp/basic/plot_12.png b/msigdb_gobp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..2a8f7ee6e72bc14386ccd9a75bfdbc11481f3a26 --- /dev/null +++ b/msigdb_gobp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dd02b3bab08d21203d243cfce4e42374044ba5b2c55c8df3e3ec3b1eafb7b383 +size 144160 diff --git a/msigdb_gobp/basic/plot_13.png b/msigdb_gobp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..8a09c9dd796275930b8cb5d80d2bb2fcc14519f7 --- /dev/null +++ b/msigdb_gobp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:215e7d3809c2a232f3bfab6ef3004d0c1d60225b02f7447b33cebb3c9b99585b +size 148311 diff --git a/msigdb_gobp/basic/plot_14.png b/msigdb_gobp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..22fa89e5f05f78c6bbdf11af5171e205083ca132 --- /dev/null +++ b/msigdb_gobp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9ff2b243e5746458218878f110b85bc98c688031745aad32f4e0863c60431ffb +size 148257 diff --git a/msigdb_gobp/basic/plot_15.png b/msigdb_gobp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..456dbf3aef09f006993adfd8c75832212f34ff36 --- /dev/null +++ b/msigdb_gobp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:130970631ad41ca6c435433eb1e55673732326ce498cf7f37635940bece8a69e +size 142275 diff --git a/msigdb_gobp/basic/plot_16.png b/msigdb_gobp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..4ad82874f1393065913be25caca04ea3a9da1d4f --- /dev/null +++ b/msigdb_gobp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:94e33386dca6a5160d151a2077b2be0fdbbee0c637b478e123609b306d679e90 +size 149260 diff --git a/msigdb_gobp/basic/plot_17.png b/msigdb_gobp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..4d5f06d8b18e94f51ec04fbd79530039705795b1 --- /dev/null +++ b/msigdb_gobp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5a3954d75ca799e613db3ed5fe3db357c2b154c79711de6a982ecc0117705dc +size 141785 diff --git a/msigdb_gobp/basic/plot_18.png b/msigdb_gobp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..01a146fec29b6c1a2dcf168d79147034294b2ef4 --- /dev/null +++ b/msigdb_gobp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c106241716a7c3581e5814880be457921cef8ba1298ef46e808ae6f00bd94938 +size 144360 diff --git a/msigdb_gobp/basic/plot_19.png b/msigdb_gobp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..07f010294e15b96ce9650516725542136f259581 --- /dev/null +++ b/msigdb_gobp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:da6002738b798a74b6cfed22d02c6ae49a1c4695abc4480683a9ba7895e6cf99 +size 144120 diff --git a/msigdb_gobp/basic/plot_2.png b/msigdb_gobp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..34667683f2eee9f569e2d8fc340048ca59f8e964 --- /dev/null +++ b/msigdb_gobp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:668bcfb4f5f90fd1581bac9ac46bef6e516fa817b62c399fa53729e4ea82254e +size 137196 diff --git a/msigdb_gobp/basic/plot_20.png b/msigdb_gobp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..1f2c907da1f4bf5d9aee9264ffdbe2b33034e839 --- /dev/null +++ b/msigdb_gobp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c4e360edc506de3de46ccbaf963a933dbddb7832e55d1132f040552f18b1c31d +size 142301 diff --git a/msigdb_gobp/basic/plot_21.png b/msigdb_gobp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..9d66815019d2c029efa48349a476649ecd119913 --- /dev/null +++ b/msigdb_gobp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:76f2cb8ed7efee5866542a4fba0b444d04ba8d64a831e7461bc06725e6fd3950 +size 149419 diff --git a/msigdb_gobp/basic/plot_22.png b/msigdb_gobp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..7475da470ad8c4f6b5bbcb4573667643fd41f38b --- /dev/null +++ b/msigdb_gobp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fec18d08415446b85c19343f90ca1babc925b443e4adb39b7da39b0010c42f35 +size 147173 diff --git a/msigdb_gobp/basic/plot_23.png b/msigdb_gobp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..37b766f20248ae72e4e8e60191a9ed8b6828de89 --- /dev/null +++ b/msigdb_gobp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9f0a6513c55650a3906766bf169ffdbe4275bbc645052b40e3f69b8c2bc92f42 +size 138475 diff --git a/msigdb_gobp/basic/plot_24.png b/msigdb_gobp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..953273ddf11fddcfac697d4f8486ed8fa403eea8 --- /dev/null +++ b/msigdb_gobp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f36ca23793b483e244550b1f2b8943def26d71ed3d0480b445858643479d6bcb +size 148505 diff --git a/msigdb_gobp/basic/plot_25.png b/msigdb_gobp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..c8bc4368cbbcfe3cf121b57ddd1f14912d72cd29 --- /dev/null +++ b/msigdb_gobp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3d7592d169c95f2a04d491fa4605481b3c45df2d0935ba31c9361f8d4a39c664 +size 151384 diff --git a/msigdb_gobp/basic/plot_26.png b/msigdb_gobp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..cf1cc15e6504fe35d14aebccef77e6fa62c533e2 --- /dev/null +++ b/msigdb_gobp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3e0de37350cf79feded9127d722a3deb9b6903fd81330cfade79923fcc46e3af +size 144564 diff --git a/msigdb_gobp/basic/plot_27.png b/msigdb_gobp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..9c35ff4e2426a63038bdcc4cc4ab9c6c75f4428e --- /dev/null +++ b/msigdb_gobp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3908b38eec67214f843629750f76b0eb32c99255436ca85b62952fe32a90275f +size 146662 diff --git a/msigdb_gobp/basic/plot_28.png b/msigdb_gobp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..749dd47731f9345db79eb9ca6e708aa2727b7bf3 --- /dev/null +++ b/msigdb_gobp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:570b346806f0bfb6f2ffa6a59acd8649fe5287b4032b06600fea4596265460ac +size 143941 diff --git a/msigdb_gobp/basic/plot_29.png b/msigdb_gobp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..7bb0c3db702e504bcba04ace9ebf448e0859e3f6 --- /dev/null +++ b/msigdb_gobp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1108b77cd9741bf6cb8f0f57ab36863bdfec3a3fd0f5fd8f7a9e8ecd22a33e12 +size 143991 diff --git a/msigdb_gobp/basic/plot_3.png b/msigdb_gobp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..5d7709e6e70dd1b3dbb3a9688667244c8edf05df --- /dev/null +++ b/msigdb_gobp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:071a26529c82cbb9bdcc4457ca7da8c864d10a4a2d80f38ce57cc4f1f693b175 +size 139777 diff --git a/msigdb_gobp/basic/plot_30.png b/msigdb_gobp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..779c9c06e56cff3a3529dbe09310d959cbf3803f --- /dev/null +++ b/msigdb_gobp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e6b394782c90d511195c72f7f2924fb10c5e83a7301bd75e28368e2b844134c6 +size 144248 diff --git a/msigdb_gobp/basic/plot_31.png b/msigdb_gobp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..99c689ff5bc366d95ae97ea3456aca5e1eb36272 --- /dev/null +++ b/msigdb_gobp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c8eabec5eea15c2b031894be4777a26d8586c015ddf2e5b1996d192895b6ae5f +size 146647 diff --git a/msigdb_gobp/basic/plot_32.png b/msigdb_gobp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..2e2f5eee196d8b616a6c430c024a89425a951014 --- /dev/null +++ b/msigdb_gobp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e4ba8a4a8d57990563440ac1a5f4dbbbad25abca8c47d5d6392a1cffca049985 +size 144395 diff --git a/msigdb_gobp/basic/plot_33.png b/msigdb_gobp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..d83aa9e4219fb8edde12cda3c4b0d4d74e8789c4 --- /dev/null +++ b/msigdb_gobp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:096ce932b218619a853d230f86e4f53b8475fcea5bd2557ec1be3e8bf1247520 +size 146505 diff --git a/msigdb_gobp/basic/plot_34.png b/msigdb_gobp/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..4b9a107f7d0ecc2ca38d89de68370673c40ae6c9 --- /dev/null +++ b/msigdb_gobp/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b47341175e4f75f52830e259a061740c281716f51ce8539fe38f0097174ab91b +size 143927 diff --git a/msigdb_gobp/basic/plot_35.png b/msigdb_gobp/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..5443661338ea23ccc2b05969733b17930e7da1c3 --- /dev/null +++ b/msigdb_gobp/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e4f13ed5e7c8defb542abd8ee543926f9b90803fab7774aa3d7233de231e0a33 +size 137895 diff --git a/msigdb_gobp/basic/plot_36.png b/msigdb_gobp/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..8302c97706374556f14b81e796f425829bf05a15 --- /dev/null +++ b/msigdb_gobp/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6bd3b176a30bf252814fa849c123c1c0afe2fa6c32cb012708b44928f7db461e +size 153611 diff --git a/msigdb_gobp/basic/plot_37.png b/msigdb_gobp/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..62eef1f238814b8a9ccb5bdf6ccb1f2a771c92eb --- /dev/null +++ b/msigdb_gobp/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:493678d7afb42c373d4a565064165ec729ed5b9b6867d7427baac7089a850e43 +size 144124 diff --git a/msigdb_gobp/basic/plot_38.png b/msigdb_gobp/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..0f715e5847b434c9d9cca7b9c0ee633dea79bbac --- /dev/null +++ b/msigdb_gobp/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fa023ed9f3d01a826b7a3bcff90d6eacbc55ec2e8d0cdf71b10d7d2c0200183a +size 143532 diff --git a/msigdb_gobp/basic/plot_39.png b/msigdb_gobp/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..7db9aed096794f8484b9875143898e5ff5669af7 --- /dev/null +++ b/msigdb_gobp/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:51a1511a96b470e342b267dcd4579ce2bb840603a6f8e43b694683a101f891b8 +size 141991 diff --git a/msigdb_gobp/basic/plot_4.png b/msigdb_gobp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..62f9095fb01179a965382d95ec17204b33afe952 --- /dev/null +++ b/msigdb_gobp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ce4f1d1e2cb758060cbdeb5890108a16a05da9e1b37c56c399c323069e65f8f5 +size 147910 diff --git a/msigdb_gobp/basic/plot_40.png b/msigdb_gobp/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..fe6a635838221f8aca44b756512207f687d447cb --- /dev/null +++ b/msigdb_gobp/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8e865e3ac99b2c9079e6ad1502496fe5a102403aa0d191a2f3c508a09ca66a2c +size 145383 diff --git a/msigdb_gobp/basic/plot_41.png b/msigdb_gobp/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..e77af847efb5be62206480a9e5a2524670584e5b --- /dev/null +++ b/msigdb_gobp/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6b904ed03151335f9627c0c8f889d51c4fa09e96ac3e7ca0f1b1e57c9258d9f9 +size 143669 diff --git a/msigdb_gobp/basic/plot_42.png b/msigdb_gobp/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..f75d0b7f5b37c15f2f58d1edcd0ab4754ad41c5d --- /dev/null +++ b/msigdb_gobp/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4a5fbfe46ffa239e92528c48f6426f5b520aee26b77423baba08a854cfccae04 +size 146426 diff --git a/msigdb_gobp/basic/plot_43.png b/msigdb_gobp/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..27538a67b1e2c297637a01c1f7c4033e7f76be00 --- /dev/null +++ b/msigdb_gobp/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2ef04f44d47b87a084546ee2c134ccf092b0d5f9c50ab20a8c54afa10667d4ac +size 144170 diff --git a/msigdb_gobp/basic/plot_44.png b/msigdb_gobp/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..a33e1b08e9d64012c8e587c770ddf0f1b9241f8b --- /dev/null +++ b/msigdb_gobp/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b992019c660e23b40baafbed32dfcbdce46130a22aef99c0d56e4f50847dfece +size 146642 diff --git a/msigdb_gobp/basic/plot_45.png b/msigdb_gobp/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..8e8d039a675a5d68bca68e5dad06fc50a55bd342 --- /dev/null +++ b/msigdb_gobp/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:387da9da308e2cf16da1f5dd000a2ad3fcbf2c121d2563f13733dd85b561a381 +size 147965 diff --git a/msigdb_gobp/basic/plot_46.png b/msigdb_gobp/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..cb7c007d74723520b3d62a578844be1cb4ea818d --- /dev/null +++ b/msigdb_gobp/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:64c89e254b70ecf9cf369b83dc0cbf9658294051bcb518bf6001bd370d7fbb1e +size 151800 diff --git a/msigdb_gobp/basic/plot_47.png b/msigdb_gobp/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..4d9465256dbadfce9ebc567a51179c12ffe96c5c --- /dev/null +++ b/msigdb_gobp/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:60c6614f0d307deef78fc518108fb465bc11e555dda6e8bd4054b8aaca0e016c +size 153782 diff --git a/msigdb_gobp/basic/plot_48.png b/msigdb_gobp/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..08fbbca6f40a65c6ac910df8f7b2a5d2158743b7 --- /dev/null +++ b/msigdb_gobp/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4483edf0354d64d77c40f15d4979d0ebc264c513d14f0bc1e7bce231e6d93912 +size 153428 diff --git a/msigdb_gobp/basic/plot_49.png b/msigdb_gobp/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..47cc3c171182c0e3bcdd69f524a188dc664f46ef --- /dev/null +++ b/msigdb_gobp/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d9c4bda2a275d1bd5900f784f7a5c5bfacab2a8504d0a4cfe034c1a1117d82d +size 142647 diff --git a/msigdb_gobp/basic/plot_5.png b/msigdb_gobp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..a88bbe39a7b62b2ac9b87206f0cc318f52818e4e --- /dev/null +++ b/msigdb_gobp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ff5a0f01baa9fd3e03d53e89f2f21abd51f3e8f03bb05d1f470d0769861d0d0f +size 144043 diff --git a/msigdb_gobp/basic/plot_6.png b/msigdb_gobp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..d2ceb04bd69edca8c25fcd2db5c8309af5c85607 --- /dev/null +++ b/msigdb_gobp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:74c424c02eb97785150db7dce1e4183bd2e401342dd32d8589d57b224671ff74 +size 149363 diff --git a/msigdb_gobp/basic/plot_7.png b/msigdb_gobp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..d745180449db5dca8a9e999c34106a733b0bc867 --- /dev/null +++ b/msigdb_gobp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7d91a062b30fa06bf771afecd5e291fb5d323876552a5c08fd1bbb896d478c19 +size 141921 diff --git a/msigdb_gobp/basic/plot_8.png b/msigdb_gobp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..9d7b614b90db74f46b248ef6dadf824e257fe959 --- /dev/null +++ b/msigdb_gobp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fc927569bbd86eb97e7c32d854f8fb56ae8205aa33aad48d0848673c3f73aab5 +size 142530 diff --git a/msigdb_gobp/basic/plot_9.png b/msigdb_gobp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..7cedada9b7dba34ae4df9861f0d2df5cc573848d --- /dev/null +++ b/msigdb_gobp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:99dc74c206d3405a65cd0463d3e122aba4e027bc20258c7f72a0e8c9059c86af +size 139892 diff --git a/msigdb_gobp/consensus.joblib b/msigdb_gobp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..bdb35d6c2adbc01f34ebba910b3668bed3ee5f09 --- /dev/null +++ b/msigdb_gobp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f24094bd3a65bf799f6aa6cb6ad89655316afe454e03ddfbb785d6276bdabad4 +size 862590 diff --git a/msigdb_gobp/df_merge.tsv b/msigdb_gobp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..f6440f866862b402153f3ba2225c26dad754caec --- /dev/null +++ b/msigdb_gobp/df_merge.tsv @@ -0,0 +1,219 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transmembrane transport 85 213 5.9351433053270926 2.935889480170374e-09 67.45631067961165 211.1359223300971 1.8122664376950308 0.3598356673827246 27.267027885156203 22.354947126810902 2.251277763144546 0.4188333713481413 1.0660608066196402e-09 4.869539903319372e-09 2.112301680737224e-07 3.9118745018290166e-10 1.2454286430957536e-08 +Mitochondrion organization 82 200 5.405420166859042 6.465664462886018e-08 56.45873786407767 188.26941747572815 1.5905300936136977 0.4100157441778524 20.15716756472138 18.40319032732565 2.034523716094369 0.4327537677377048 3.123282959158352e-10 6.217563308111418e-06 5.8875686649123916e-09 3.8035330519255816e-10 4.4649155130100446e-11 +Anion transport 41 67 4.817090102378592 1.4566692139172943e-06 26.953883495145632 69.53155339805825 1.854216838065017 0.2425457725148559 12.138973160217668 8.434296289414672 2.014686633079497 0.3448588040224388 7.58337418509971e-07 5.046636171997423e-06 2.514383017238032e-05 7.696439903211845e-06 4.22991163736517e-06 +Organic anion transport 26 43 4.739580566015254 2.141610703887409e-06 18.575242718446603 46.57281553398058 1.6158560948583975 0.2692356013040078 9.46386426798458 5.9518324529926545 1.7470285445738305 0.3371920110610632 0.0071024339129455 0.005312366512423 0.0135143906382874 0.0247882554789765 0.0103209749302633 +Membrane lipid metabolic process 20 37 4.664584304398999 3.092415346017674e-06 15.813106796116504 37.71116504854369 1.423850539998867 0.1808469841706369 6.252884620395072 4.742042041181393 2.289538519382486 0.2724480316274368 1.1638414505213788e-06 0.0002882472650011 2.482529882415532e-06 0.0001639845862835 2.750566378038634e-07 +Anion transmembrane transport 27 40 4.640049919367094 3.48325025845142e-06 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 1.3813718961226376e-05 0.0002089603767857 0.0001103968380003 1.7526077333075058e-05 2.6715701254780905e-05 +Ion transmembrane transport 69 154 4.618400013374302 3.867102377874687e-06 47.09466019417476 154.11893203883494 1.555073205784263 0.3634279635891347 19.61122797656 15.97124025754773 1.9676287128633565 0.411597796705808 1.4481822019963076e-06 1.4602787132982253e-06 3.566632351568281e-05 7.044810596570091e-07 4.445748649926079e-06 +Ion transport 88 210 4.582058119795409 4.604218803772042e-06 59.95631067961165 203.33495145631068 1.28794420214731 0.4483240343684334 22.7179419701651 20.293344878478432 1.852388371824549 0.4292871393353351 5.987950129413595e-06 1.2728285955860117e-06 3.722378035575862e-05 1.1079870870445268e-05 8.081845853433078e-06 +Lipid metabolic process 110 294 4.546397592058179 5.457190360935726e-06 70.49514563106796 273.7014563106796 0.4234492243219149 0.5257500979287635 24.98470358696109 28.74867152381156 1.6795947056521872 0.4126649977131845 1.0497290805952012e-10 7.097367432404933e-05 1.3797685039908169e-06 1.2328340455002806e-07 1.0902099729855796e-14 +Mitochondrial transport 23 85 4.400740742225707 1.0788196088018507e-05 26.76456310679612 83.42233009708738 1.9353944346565397 0.260698067067068 11.29934298946582 6.8259418360610375 1.9296757414965091 0.3685496297416806 1.6173201961002144e-09 1.4327005060406392e-06 7.413059032363764e-07 7.860631072311927e-10 4.0239026049171793e-08 +Sphingolipid metabolic process 18 28 4.317123674310834 1.5807559760716572e-05 12.631067961165048 29.174757281553397 1.3566630100256978 0.1614907042591146 4.986857078326301 3.461093559903884 2.232073980338918 0.2503191978902473 1.9198882875144747e-06 9.134926391858884e-05 3.587283440596808e-06 0.0004664122096076 9.656208072308901e-08 +Lipid localization 30 80 4.312129552517813 1.61689642084184e-05 20.1504854368932 74.27912621359224 1.3966421040883936 0.3001252105784707 7.306180038477171 9.39465098860316 1.572418240819249 0.3627304234720817 9.29420111845956e-07 1.0521447257919692e-05 1.0082444993827024e-05 7.5226231976256625e-06 2.5785354424225223e-05 +Organic acid transport 22 46 4.276004080506537 1.902777366802333e-05 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 0.0015690326004637 0.0044530255668373 0.0455395680691261 0.0190102387597145 0.0026695027153566 +Secondary alcohol metabolic process 17 46 4.178061269188547 2.9400446481586684e-05 12.097087378640778 42.24514563106796 1.5200936296432006 0.2566232504859334 4.463475425703621 3.883072640851752 1.3223501002339118 0.3210874999447533 2.1551560248956528e-11 3.8136316660464e-06 1.992207957598601e-06 2.4410219840752032e-11 4.2784229944579465e-09 +Mitochondrial transmembrane transport 27 51 4.106059328274172 4.024661523116535e-05 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 8.273688485010726e-08 3.3275006405435018e-06 1.6673556615896856e-06 1.5119657667001427e-08 2.7694389412322284e-09 +Steroid metabolic process 31 71 3.859054123127185 0.0001138267292912 17.82766990291262 66.9247572815534 0.9974586731388552 0.3270410156332073 6.090491666967852 5.93996409793671 1.7133199907504504 0.3720334828404655 2.075048491011766e-09 0.0009563326986827 0.0001419203073907 4.316530549904326e-08 2.9591827797718625e-08 +Mitochondrial respiratory chain complex assembly 17 39 3.8292633894629735 0.0001285273901487 14.427184466019416 38.300970873786405 1.6683402305651691 0.229838901803248 5.648441561419256 5.588363345618 1.6629328950455762 0.3088219725228932 7.938307532746076e-06 0.0009994289576092 2.9164279923466545e-05 7.128358559697429e-05 1.4736498944525232e-06 +Lipid biosynthetic process 64 154 3.788227312375687 0.0001517260006573 38.012135922330096 141.7257281553398 0.5620793375816577 0.4367444072022249 15.729119254593195 17.314902336322657 1.553306672697969 0.3832082090559359 7.702450713435653e-06 0.0170554111715972 0.0008895026951456 0.0001114306221239 9.214945328204732e-08 +Cellular lipid metabolic process 81 221 3.770538142341679 0.0001628959021915 55.06310679611651 205.83495145631068 0.2402431693065998 0.4937242414097398 20.280338607556292 23.717838556123585 1.6370289909336062 0.4061780961812439 1.2598143138067984e-06 0.0021013729163774 1.5550481794673234e-05 0.0001140933698052 1.722588847728435e-11 +Sterol metabolic process 15 42 3.763513396669183 0.0001675427471452 11.932038834951456 38.44660194174757 1.1656335789111734 0.2523239777622673 4.346099994655023 4.0619669904912925 1.6676089351046874 0.3062687621764124 1.2668540206410184e-09 0.0007736613442574 0.0001791038943355 1.6861180298656515e-09 9.939079120256544e-08 +Carboxylic acid transport 16 32 3.750825452438684 0.0001762533685396 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 0.0090712071913285 0.0016998925321585 0.0195932975716513 0.0434375027766798 0.0129452724374584 +Cation transmembrane transport 40 120 3.738408739899719 0.0001851886918264 33.43446601941748 118.4004854368932 1.1701058025505957 0.4085228823574113 14.425169362008605 12.553856783980793 1.6663185381795875 0.4066910074955585 0.0018598402688397 0.0021625863753798 0.0302892137886333 0.000836365583236 0.0025548113950988 +Mitochondrial membrane organization 24 50 3.642967531367917 0.0002695128454108 16.983009708737864 46.91019417475728 1.283632855732258 0.3380738792929293 7.413069190635445 4.027718639381892 1.6948461264793506 0.367302285357348 1.3878447502696666e-05 0.0803423183551439 0.0145498805195169 2.0855419147613898e-05 5.5990954362047707e-05 +Organic acid transmembrane transport 16 29 3.63706619265532 0.0002757610836936 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 0.0017128390213521 0.0006152777977496 0.0077976080130679 0.0133275956191841 0.0016116153879735 +Membrane organization 70 227 3.634043903426497 0.000279013352638 62.02427184466019 223.60922330097088 0.9560408776070136 0.5603311757674675 21.467957454898308 21.375973545731355 1.611091026762519 0.4273954777865132 0.000388652464227 0.013983226891474 0.0342623603846053 0.0005191433000468 0.0003198140282795 +Inorganic ion transmembrane transport 46 115 3.633884258549124 0.0002791861411375 32.300970873786405 111.99514563106796 0.9881513097876132 0.4268253140664947 13.185263141323642 11.586314982845243 1.7161030277526947 0.4113555760685328 0.0014695694129473 0.0062401067909374 0.0189462171028306 0.0007141860470926 0.0088955221096143 +Vacuole organization 13 53 3.5655794785391413 0.00036305311421 14.220873786407768 51.74514563106796 0.8524122478550634 0.3147425083910056 5.370022076358251 7.439112114793103 1.7567175511320523 0.3563110134355993 0.0116311476998962 0.040162898931708 0.0180511427811038 0.0137034160901337 0.0187378186383463 +Glycoprotein biosynthetic process 25 55 3.525035649695188 0.0004234258041038 16.72087378640777 51.87378640776699 1.042113998842759 0.381483262234126 6.756316800759528 8.908847583990125 1.5232206853916193 0.3819786061588057 0.0070568460477726 0.6104712262815544 0.559345788555234 0.0069031854729917 0.0003639104006096 +Protein targeting to mitochondrion 16 46 3.4982384098727923 0.0004683422728035 14.980582524271844 46.067961165048544 1.7767024064550243 0.249920045184344 6.494927942714517 4.708517660750424 1.5433015545903224 0.3384144763122346 8.891107850224192e-07 0.0090901991927659 0.0016898291272514 1.3685697691206764e-06 9.00513822591663e-07 +Protein localization to mitochondrion 22 59 3.490734624127445 0.0004816944556416 18.37621359223301 58.6747572815534 1.743973973786015 0.2835887708870952 7.329731795051445 5.553888141183353 1.6030721833013164 0.3628376459321563 2.9122288335331445e-07 0.0157967173614079 0.0041233790686571 3.372387659800037e-07 9.367278948654192e-07 +Protein targeting 38 118 3.4701070608746143 0.0005202509489927 30.48543689320388 111.54126213592232 1.595466660966077 0.3336055854889273 10.683999539888966 11.70327920021055 1.673091584234216 0.3988264387816677 1.340858377472435e-07 0.0341253829944142 0.0031934737257392 8.252412226752362e-07 1.2584397057270845e-05 +Membrane lipid biosynthetic process 15 22 3.4068367985823267 0.0006572041101968 8.866504854368932 23.050970873786408 1.3229385051208649 0.2431293012321725 4.229937732502716 3.4850337476777224 1.635527795490498 0.2996124846932806 0.0020074317754622 0.0610672127355571 0.0084964197325681 0.014921436170793 0.0005681851019641 +Cation transport 51 160 3.402966895980386 0.0006665835644663 40.9247572815534 152.4733009708738 1.0106305648473772 0.4693050539746304 15.98502541638414 15.374508146736815 1.5607432077940149 0.4143686874753333 0.0031849547884717 0.0006053327615472 0.0092647359152756 0.0023981559256283 0.0020621699124183 +Ceramide metabolic process 11 18 3.3513216656500195 0.0008042682196405 8.191747572815533 19.060679611650485 1.0632949889077032 0.1865092544415649 3.2982239784478966 2.5917545738626013 1.8901201919357584 0.2494992632187684 2.544040351976533e-05 0.0316917589218704 0.0002294243633388 0.0025564989720558 1.4660781943737655e-05 +Lytic vacuole organization 10 24 3.347982423798781 0.0008140217377814 8.677184466019417 23.79368932038835 1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 0.0013460838807173 0.0031199538764304 0.0002923880316579 0.0006098715494409 0.0001266725713312 +Glycosylation 20 47 3.280817194025655 0.0010350680664057 13.33495145631068 45.42718446601942 0.831363055351092 0.4028474919440285 5.5712021107485015 7.578523489860055 1.3433056638769032 0.3649215649501745 0.0379938965487335 0.18840613689087 0.4739160593181645 0.0178167655304828 0.0022652021467866 +Carbohydrate derivative catabolic process 16 38 3.267554243682912 0.0010848107588543 9.92233009708738 34.20388349514563 -0.0123085756499559 0.2707665028006943 3.843893961107642 3.291233496452993 1.7787241070250257 0.2878972939517332 3.290373838011977e-06 0.107450887051756 0.025600369736322 0.0004623658808587 3.3773183671463215e-05 +Protein insertion into membrane 14 29 3.201973758971659 0.0013648943092883 9.861650485436892 27.67718446601942 1.4180388387951812 0.2751856944202687 4.426616888970974 3.3195747527036987 1.508549988584809 0.3318307488597651 1.1531117107949e-06 0.2222355866483168 0.3958350013250431 2.9025386920569695e-05 2.617480968110606e-05 +Glycoprotein metabolic process 25 62 3.1780589250993767 0.0014826461515307 18.59223300970874 59.577669902912625 0.8707431654759812 0.409720724299967 7.543964208858723 9.989377193127202 1.488085349392555 0.3835029669336279 0.0248970578757025 0.6748528810231245 0.6541748397456324 0.0228373562403534 0.0033144537056698 +Hormone metabolic process 9 29 3.1649308871857604 0.0015511979228564 8.95631067961165 28.65776699029126 1.130508313948193 0.2963365150575847 3.9674689274001818 2.5345884681715156 1.346801337886388 0.3240077568826507 0.0003658591860306 0.0012680289055886 0.0003681825850077 0.0005881937342261 0.0192471263691677 +Liposaccharide metabolic process 8 18 3.065174743482805 0.002175428534697 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 0.0001923171429862 0.0028326312129738 0.0002491331255683 0.0027943802514918 0.0017963005545976 +Alcohol metabolic process 25 87 3.0597862361984243 0.0022149502032637 19.300970873786408 81.99029126213593 1.0392616248309592 0.3936245775900834 6.9548962308345 7.403089286448431 1.208378917036781 0.3759976884392474 1.8213243410162728e-08 0.0005171634979467 0.0002038823307389 1.768784552524243e-07 9.814753258299877e-07 +Regulation of hormone levels 14 68 3.031404465227541 0.0024341893681187 15.682038834951456 62.25485436893204 0.7754141622249116 0.4638741971732045 6.630568201753413 6.49574922456989 1.111399769110166 0.3798141702267368 0.0030961063801234 0.0214233577780816 0.0197404621143563 0.0174682229057586 0.1078151549831653 +Lipid catabolic process 31 87 3.005457839436662 0.0026518135615285 19.063106796116504 76.78883495145631 -0.5842777756568693 0.3221402103477144 7.364695240054802 7.224659201956135 1.6856251653592422 0.3322230834236141 2.1542248334768256e-06 0.0108639142832434 5.7273741438673e-05 0.0013218952114371 1.0814291217340889e-07 +Organophosphate ester transport 14 25 3.003749131672892 0.002666751157303 10.29126213592233 27.364077669902912 1.4948680330369015 0.1889391065154625 4.84293313185659 4.31957284765524 1.6451867819665518 0.2532208690981375 0.0003402554314994 0.3228460923172884 0.0074628704993106 0.0001239561832085 0.0004008657195021 +Sphingolipid biosynthetic process 9 15 2.992748982141366 0.0027647704545619 6.543689320388349 16.33252427184466 1.3108583596388097 0.2293036031089034 3.2058099533310203 2.4273143169149307 1.5209865792019848 0.2861850290041513 0.0058865955831034 0.0337662417977069 0.0200220567053061 0.0556276904991455 0.0004954067345962 +Meiotic cell cycle process 19 46 2.9878485845858385 0.0028094870547488 9.402912621359222 38.95631067961165 0.0819580797367834 0.7031226625549499 4.572266679077019 5.445050659101089 0.7112044262993327 0.2925129435822093 0.4079459397950573 0.4364495014109603 0.315260036101858 0.5418851868443096 0.111596544082692 +Alternative mrna splicing via spliceosome 18 45 2.987438176286405 0.002813261882433 14.009708737864075 40.728155339805824 0.0708159133159534 0.5694011596603432 6.451830696216548 3.032011011191426 1.225863726972057 0.3649890000258197 0.0087264472984559 1.0 0.4688773052385803 0.0197625026052712 0.0002305240226419 +Response to oxidative stress 26 103 2.968757459515673 0.0029900650095622 18.145631067961165 95.9757281553398 0.5057872201816154 0.5358657948719677 6.785060354870026 9.30128883458378 0.9511882590088212 0.3606217523881886 0.0081544763562242 0.0005212692357823 0.0001334034605742 0.0127530618045781 0.0284866618256956 +Steroid biosynthetic process 21 49 2.966983938555446 0.0030073666880687 11.728155339805824 44.80825242718446 0.9874364787035632 0.3935759881445143 5.016369659264937 4.35272817633461 1.2862817592315925 0.3680333006848349 1.54486500983595e-05 0.0118439766153403 0.0025939624536197 0.0001227255087686 3.6955559870808975e-06 +Aminoglycan metabolic process 7 15 2.960659887404953 0.0030698073526831 6.650485436893204 15.218446601941748 0.5538240398360251 0.1973407167351751 2.4739761552565955 2.4752855115427597 1.8355272359461776 0.2521795038965069 0.0016347429488832 0.2633971592089756 0.0228098510804851 0.0174389793074279 0.0099258782765325 +Establishment of protein localization to organelle 45 186 2.8787158084869504 0.0039929797853985 40.4247572815534 180.123786407767 0.6176411706537287 0.628535284461401 14.116769229706104 14.40373863390995 1.0281809729691214 0.3983757503188239 2.178050481958636e-05 0.0969357821599332 0.0610249064717706 2.053094791758222e-05 0.0012294651255193 +Nadh dehydrogenase complex assembly 14 28 2.8481289075383844 0.0043977107558879 9.266990291262136 26.96359223300971 1.1245271541492263 0.3013677937017552 4.122702675359976 4.029157649894909 1.4460543016521823 0.3224564676521605 0.0009894734466785 0.0316917589218704 0.0182749379957494 0.0025564989720558 7.783061920382117e-05 +Cellular lipid catabolic process 29 75 2.8390709681950823 0.0045245092918373 17.41504854368932 64.87135922330097 -0.5696683615842715 0.3298363628621607 6.7262755853496445 5.714948470160487 1.6899125472444 0.3353762314902799 1.0555212441647942e-06 0.0042260027485698 6.574170025195322e-06 0.0017130269905794 6.0588086311664665e-09 +Cellular hormone metabolic process 6 19 2.8305860800309017 0.0046462806740652 5.441747572815534 17.32766990291262 0.9908884218524354 0.2940959275691314 2.8170777488519256 1.7185203072340225 1.2515909253444888 0.3031653223897966 0.0004997154973387 0.0019583087959773 0.0001348318070603 0.0014327621348651 0.0111707611872444 +Membrane lipid catabolic process 7 13 2.8158596768231003 0.0048646909340033 5.854368932038835 11.361650485436892 0.500872843713425 0.1363587272813367 1.9603237645724247 0.9867004907377388 2.113024793917032 0.2289617793743788 7.027482060880119e-07 0.0042324529563037 3.741089337723684e-05 0.0012358112224234 2.2237850571674797e-06 +Cytochrome complex assembly 5 12 2.807148575659858 0.0049982182724315 5.339805825242719 11.616504854368932 1.5489281771301031 0.1834582376033618 2.45860248431673 2.439266047793512 1.3189185418401956 0.2620853228235733 0.000314596877379 0.0119629297909749 0.0003222994847708 0.0001512549233666 0.0054053690368969 +Establishment of protein localization to membrane 23 89 2.8065528372875064 0.0050074699500846 23.133495145631063 87.3616504854369 1.231448880072231 0.4195243824117992 8.397245527204214 9.510228790351464 1.3947369206386535 0.4065372973031916 0.0001902872935071 0.0780419946670056 0.1402699688168154 0.0042920939654292 0.0022076316008824 +Glycosphingolipid metabolic process 6 10 2.793943428523031 0.0052069586731331 4.764563106796117 9.184466019417476 0.4485135251287195 0.1553285492394019 1.7516723087054535 1.7320372023153958 1.93068386398988 0.2217231968869004 0.0002652289805869 0.0005458668398673 0.0002865257018003 0.0081443152876 0.0008750939624126 +Regulation of autophagy 25 103 2.7577522701995685 0.0058200286104324 20.118932038834952 94.3495145631068 0.711099590941891 0.531831837860264 6.9602150135047 11.998348379757145 0.9791686068293384 0.3767967479294735 0.0094234524574626 0.0103631785157378 0.0173466265153601 0.0068892272769731 0.0034527643325308 +Regulation of membrane potential 13 68 2.74642752359812 0.0060248196113334 12.04611650485437 57.75970873786408 0.1124751219273164 0.6676030681415518 5.082838961521082 5.41286026291516 0.7215479250938304 0.3068872738743891 0.0019468990042072 0.0448222654886068 0.0214085254865267 0.0020564697734096 0.0123993048317629 +Nitrogen compound transport 147 608 2.73880680438093 0.0061662596687301 134.15533980582524 569.4538834951456 0.9072063241864304 0.6401677607980054 37.1767641393764 58.81145048559368 1.470232145086419 0.4303798393104362 5.225072884441243e-05 0.0334402936424034 0.0035286546542089 4.212407439291104e-05 1.558871704390191e-06 +Inorganic anion transport 15 25 2.7374957043512635 0.0061908928594045 9.900485436893204 25.351941747572816 1.3590123122148194 0.2025490755989976 4.608697956226863 4.352203003870329 1.5972877171217004 0.2769639658120273 1.968153663881454e-05 2.0505002718798684e-05 5.5694737187114106e-05 6.03732836128942e-06 0.000453975704248 +Regulation of alternative mrna splicing via spliceosome 16 33 2.7300185020025807 0.0063330771107394 10.609223300970871 30.575242718446603 0.1468114472042654 0.5502297177540902 5.108075880658377 2.6128265930148187 1.194088433027589 0.3536418549118582 0.0115084565191122 1.0 0.3837477700803094 0.0311941867040692 0.0001002672586078 +Establishment of protein localization to mitochondrial membrane 7 19 2.719094069062985 0.0065460988503636 5.572815533980583 16.524271844660195 1.1986544459127668 0.291784793504827 2.8501471321161915 2.5441524813639957 1.2232399066733852 0.3232066755573589 4.724795318701029e-07 0.1244478155008913 0.2339121686337894 2.7848183597346687e-06 2.8968816708506228e-05 +Inner mitochondrial membrane organization 14 22 2.7190412863817204 0.0065471435477495 9.985436893203884 20.800970873786408 1.138268089020681 0.2873707765098114 4.6289277788641146 2.4012939531921327 1.609232985153232 0.3229583948801056 0.0005068901363743 1.0 0.3060304729743218 0.0019200914773881 5.203006206071089e-05 +Carbohydrate derivative transport 9 13 2.698099815145815 0.0069736527537387 7.924757281553398 17.024271844660195 1.3665639952580566 0.1869571280171947 4.210097511648942 2.624454303682939 1.5541767319140831 0.2467993156006303 0.0389400516653052 0.2027885470531376 0.0746250944081647 0.0254140783095469 0.0230912453221162 +Endoplasmic reticulum organization 17 43 2.697233747937432 0.0069918172389342 14.91747572815534 43.67718446601942 1.1418424810127707 0.3725584991544436 6.208589840117394 4.768440325801463 1.6823827875834556 0.3705219831566139 0.0611623253242139 1.0 0.5285075461630524 0.114772391772967 0.0757419688955735 +Negative regulation of mrna catabolic process 13 24 2.663355839259151 0.0077365553792823 9.169902912621358 24.631067961165048 0.5652120707700043 0.4958815262040553 4.097153521759381 1.8459627491120816 1.1372403168685192 0.3560626632344691 0.0002259737017305 1.0 1.0 0.0007319888819485 4.637471222605554e-05 +Regeneration 10 34 2.647986280042152 0.0080972811344968 6.191747572815534 31.563106796116504 0.5380382799076718 0.5740012495882397 3.277553825936591 3.489707203654107 0.7812061797301654 0.3285807753592402 0.0275911301534687 0.4047844567784328 0.0839971460237413 0.0434375027766798 0.0693354775232653 +Ceramide catabolic process 5 8 2.6470605199119066 0.0081194820593422 3.8592233009708736 6.531553398058253 0.1286784152295923 0.1423502941444668 1.429436503356119 0.7012295128365029 2.0219843992394857 0.2259194528389771 1.1107568426286228e-05 0.0573151884822011 0.0058956460302812 0.0333651833289618 9.246798264487089e-06 +Circulatory system process 19 81 2.6293488027982663 0.0085548564441184 17.152912621359224 72.00970873786407 0.7968086684699157 0.4206667688960129 5.8797345113877215 8.195718922280731 1.282615010632819 0.3676426088525382 0.0391510262234936 0.3335237920762112 0.2134959758347531 0.0729360201059564 0.0143208854717701 +Regulation of lipid metabolic process 22 54 2.573984598684696 0.0100534748323937 12.599514563106796 52.890776699029125 0.2189053156740071 0.4007176079141414 5.562295027948738 7.005213895866115 1.3822804240908182 0.3523493088444139 0.01830696956132 0.0140495695480186 0.1180093146266414 0.0187415693626724 0.0238652598268483 +Negative regulation of rna catabolic process 14 32 2.573137407007102 0.0100781186895944 11.186893203883496 32.42718446601942 0.419853700893663 0.5432159718224696 4.924332595678975 2.3133296381008863 1.0980554146273172 0.3596399931743501 0.0010988870569684 1.0 1.0 0.0027943802514918 0.0004297622117065 +Meiotic cell cycle 25 65 2.5728887436184644 0.0100853622340189 12.92233009708738 55.842233009708735 0.0993622526463597 0.6833673987108698 5.626634511843725 6.778883751516931 0.7601304899640036 0.3087139543797219 0.2474170948060338 0.1690580957545682 0.1847545446978684 0.3091366197690979 0.0324099964250497 +Antigen processing and presentation of endogenous peptide antigen 6 9 2.567119000989019 0.0102547413044709 2.638349514563106 6.390776699029126 1.097011591019633 0.2766562869747734 1.460743657586565 1.3760123823390067 1.0015631459591094 0.2785574288267012 0.0004793920471104 1.0 1.0 0.0002865546760543 1.5745699404944486e-06 +Antigen processing and presentation of endogenous antigen 6 9 2.567119000989019 0.0102547413044709 2.6529126213592233 6.463592233009709 1.0779744166035472 0.2832041157954688 1.4492771087670022 1.3990755299770097 1.00991421519493 0.2818848392729987 0.0006394246968973 1.0 1.0 0.0003832983840783 2.8288826421402382e-06 +Regulation of mitochondrion organization 13 47 2.562559204110934 0.010390387097648 12.08980582524272 45.08252427184466 0.8217268052205459 0.4563186211764868 4.409741308614158 5.146210353910189 1.120993905462196 0.3778427085178187 0.0358284858060962 0.1027744496234552 0.095403296278499 0.0188658439386598 0.0189886655278426 +Regulation of rna splicing 21 91 2.538565216100852 0.0111308055384395 27.91990291262136 86.5121359223301 0.1323494025528259 0.5572910110956871 9.72639747067558 5.208502039558804 1.4178017247437722 0.381677869420044 0.0127815819864285 1.0 0.7353802816028594 0.0168565811109024 4.536860846897307e-07 +Regulation of blood pressure 8 19 2.5353012298311106 0.0112350668627245 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0054117803203034 0.2486824788491954 0.0191373699896123 0.0027943802514918 0.0017963005545976 +Sodium ion transport 10 25 2.529628143408668 0.0114183470029742 7.286407766990291 24.194174757281555 0.366064924510469 0.599746317765829 3.595508215659048 3.4684661348618055 0.8333080580344709 0.3307550501478689 0.2808760756678738 1.0 1.0 0.2073874230983389 0.5035077464124297 +Sodium ion transmembrane transport 10 21 2.5221667749213483 0.011663439642618 6.230582524271845 19.861650485436893 0.3704792335969762 0.5741696766418313 3.3118992073574036 3.0326356242212613 0.8979196459015502 0.333569210239074 0.1419220051794165 1.0 1.0 0.0989961492390201 0.4669683629396246 +Protein localization to organelle 85 344 2.514110760028727 0.0119332949581698 67.3495145631068 323.95873786407765 0.2673038377247629 0.817015428896562 19.766210620364816 30.728939371736654 0.7017218037327799 0.31039729979455 0.00773963600781 0.2892436943684167 0.1808307943480618 0.0035796637888487 0.0013142084575362 +Positive regulation of necrotic cell death 2 7 2.488332920499028 0.0128343526509375 1.577669902912621 5.262135922330097 0.5638344924795549 0.4335998879538771 1.168471912149588 0.9650309623137224 1.027471527178098 0.3152978961085739 0.0022412273106297 0.0010343090391069 0.0001045037164678 0.0015206572897169 0.0106255777102749 +Rna stabilization 12 27 2.485184804789646 0.0129484195754081 9.359223300970871 27.37621359223301 0.4792302048577673 0.5262457931829767 4.411160534464403 1.6856669427134765 1.0994939820726763 0.3614208213771557 0.0115084565191122 1.0 1.0 0.0311941867040692 0.0022946198906289 +Regulation of atp metabolic process 6 28 2.4563154447909934 0.0140369881886437 5.475728155339806 26.274271844660195 0.334640781503248 0.5621665759070464 3.158728576082886 2.9845912055027837 0.8610357625710494 0.3157017370833172 0.0063910968833065 0.0348230103466341 0.0002923880316579 0.0033194180753683 0.0256930133995238 +Chemical homeostasis 53 187 2.4556865651946227 0.01406157421088 43.762135922330096 177.7597087378641 0.7082111793088889 0.511106347874914 13.668464281922288 17.87763227716401 1.3204137511810292 0.4179418895476048 0.007198530821096 0.0539818023751681 0.096307444167305 0.0320748284478314 0.0017539031798951 +Protein import 20 85 2.441835858088448 0.0146127889251299 18.941747572815533 84.88106796116504 0.6008949453203009 0.582747226306641 7.950789473798742 5.928615059974957 0.9194508312715092 0.3730411656244653 0.0040387180795372 0.0556730506346275 0.0959672094353915 0.0040798324190844 0.0498277241710053 +Glycolipid catabolic process 4 8 2.431743917514916 0.0150263269813488 3.6310679611650487 6.451456310679611 0.1059933679561382 0.1697430158083476 1.434595381284437 0.7664524352299261 1.9023109688101565 0.2365791262889882 0.0002477926457577 0.0573151884822011 0.0058956460302812 0.0333651833289618 0.0001590313802548 +Antigen processing and presentation 8 25 2.426895727324999 0.0152286320513399 6.201456310679611 22.17718446601942 0.8231471183465873 0.4220086818460768 2.970845032857872 3.056135613532617 0.9682333159777928 0.3245513416930483 0.004965618948224 0.2449590299452383 0.4307061333231872 0.0025564989720558 0.001584251501391 +Dicarboxylic acid transport 7 17 2.417881180841367 0.0156111735138209 5.718446601941747 16.097087378640776 1.1205667041867788 0.2998586575349944 3.584398436287638 2.226340822602054 1.0973546365412417 0.2986830136605488 0.1120171481403903 0.0179094063189584 0.0636449972198752 0.0824073873197279 0.3352387529422323 +Amino acid transport 10 19 2.416198370592089 0.0156835143671323 7.771844660194175 19.75 0.8410032854505353 0.3449280742441291 4.117377746800764 3.003739578643708 1.287399790463736 0.3206698223659758 0.5789114031973811 0.288471198078913 0.4945801471111566 0.5054615584867167 0.434304903746751 +Ceramide biosynthetic process 7 10 2.4085987287078607 0.0160138942884668 4.033980582524272 10.24757281553398 1.048715387316577 0.2344614502118888 2.237979905601341 2.0281678881596505 1.4071730245015133 0.2685344998940062 0.0158339836124163 0.012648542478749 0.0459506122728715 0.0530915597366878 0.0062617463102783 +Diol metabolic process 4 7 2.400489807835498 0.0163731467067005 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0092378701630156 0.0756950383436983 0.0104494791604543 0.0569248849368824 0.000745702459351 +Diol biosynthetic process 4 7 2.400489807835498 0.0163731467067005 2.5315533980582523 7.747572815533981 0.934609081792458 0.2730932800244148 1.324333323602112 0.9054146354978068 1.183401939154622 0.2688651038177358 0.0050194064450486 0.0619434524836269 0.0069232563631819 0.0388074443523606 0.0002481332774246 +Chromosome organization involved in meiotic cell cycle 6 18 2.3928100584047094 0.0167198942775403 4.191747572815534 17.075242718446603 0.5477868656890444 0.537972059729365 2.504293372491294 1.9587168103198336 0.797047721972746 0.3210313218702831 0.083729479939788 1.0 0.3060304729743218 0.2282899009392132 0.0082637154660588 +Lipoprotein metabolic process 8 21 2.389055920258276 0.0168917310714262 5.504854368932039 19.114077669902912 1.0723975558987071 0.2794846862458811 2.648039342123219 3.7213756556771336 1.2556798055308762 0.2951644225033464 0.0891736307606576 0.0082661149627475 0.0507760863542232 0.056666707333059 0.1191020144375228 +Aerobic respiration 18 88 2.387321412205432 0.0169716462491191 23.075242718446603 86.43446601941747 0.4685851027775424 0.4381258038241513 10.546552774557412 6.275478278783705 1.570513830163352 0.3792860784147517 0.0005081281690553 0.0010416604701427 2.4631274400717543e-05 0.0001366165203894 0.0002545584408594 +Nucleotide transport 6 10 2.354978628518225 0.0185237710203953 6.189320388349515 13.405339805825244 1.3859091987706234 0.2148450774807873 3.399469193898354 2.266957807297256 1.34942986946681 0.2785977875693559 0.005499153241604 0.1201219647894398 0.0020204438885922 0.0033995973847004 0.0075122167669424 +Cellular response to chemical stress 23 84 2.349522093315762 0.0187975285208705 15.75728155339806 79.70145631067962 0.402779466671678 0.6562176319163813 6.265123092751621 7.907578877532739 0.7656094121344978 0.3407433272819883 0.1279873592585487 0.0284623802887982 0.0086123730376245 0.2234124792193484 0.1154233172410249 +Response to oxygen levels 19 70 2.349281950099933 0.018809657519986 12.5 62.737864077669904 0.8042614609462893 0.4659445696529398 5.042296826006319 7.106965221607376 0.959407798819026 0.3671515409983293 0.4545389534642073 0.2442831333906128 0.121326118019958 0.3327169289194127 0.012923356170122 +Sphingoid metabolic process 4 5 2.348983980206376 0.0188247167075328 2.337378640776699 5.174757281553398 0.8258730035764346 0.2192038420096116 1.196784089801513 0.5941001920342514 1.4738240163378542 0.2563928956394505 0.0022412273106297 0.0479914252810258 0.0938999510605359 0.2191369015278419 5.489393781591606e-05 +Sulfur compound transport 2 6 2.344142127468529 0.0190709025455781 3.504854368932039 9.429611650485436 1.339223354728307 0.2167503093092372 2.046184165461596 2.1092484385198076 1.0728301411615704 0.2604171804663498 0.0636918076451499 0.0112943240362007 0.0040346592713098 0.0458410907711806 0.2151867556135544 +Glycerolipid biosynthetic process 19 50 2.340873269907884 0.0192386962573927 13.466019417475728 44.71844660194175 0.9430872689732808 0.3767257192898063 6.88753698417372 8.249645447783736 1.3199493331746477 0.3584243730449019 0.243242977766824 1.0 0.5329680993593728 0.1546197878568274 0.0579961117020803 +Autophagy of mitochondrion 9 33 2.337664861391485 0.0194046403580583 8.643203883495145 32.55582524271845 0.5912176019297528 0.507260115546458 3.9310041488944902 4.499114265424183 1.01585008111736 0.3556742421157408 0.0611623253242139 0.0060673937801388 0.0384628064123942 0.0379484136991646 0.0757419688955735 +Inorganic anion transmembrane transport 7 9 2.317658573977825 0.02046788411479 3.4101941747572817 8.983009708737864 1.1245392058053427 0.2357455210082705 2.3748669786284156 1.7214248641786654 1.1968417731555627 0.2697184972505711 0.0081826700022156 0.1330370821365251 0.0325598174288622 0.0051006501172469 0.0501437556032915 +Connective tissue development 10 26 2.3078730605268074 0.0210061978211697 6.759708737864078 24.91747572815534 0.897701915164713 0.400129048313066 2.7453452066208146 3.8608044632925673 0.8993390896039578 0.3237981500894625 0.0674291551859807 0.1299869053709053 0.1308362822791355 0.2034119314097438 0.1707921550094875 +Oligosaccharide metabolic process 3 6 2.303461329936765 0.0212529004934343 3.0606796116504853 6.179611650485437 -0.0148577354153068 0.2267163537664357 1.4017006052191363 1.1242135739548185 1.7186048285621385 0.2671195008920222 0.1343134370761026 1.0 0.2030300441679912 0.4340702418800846 0.0234644839392777 +Reactive oxygen species metabolic process 10 44 2.293407766828337 0.02182453990091 8.992718446601941 41.58252427184466 0.1882010381098686 0.5572409607797985 3.97778361816737 3.7817247614998335 0.8956128339998639 0.3184164905246112 0.0438232229535632 0.1106003446312499 0.0270700304702826 0.0234059346063466 0.0254459154724213 +Regulation of necrotic cell death 4 12 2.291814489177457 0.0219163502287009 2.6771844660194173 11.71359223300971 0.2977530378262362 0.4578180986081704 1.5454800476301118 1.252380145124011 1.0198350476395044 0.2956255904252384 0.0008023159172073 0.0076498462283805 0.0022569298755563 0.0039153945652928 0.0088588626715525 +Positive regulation of mitochondrial translation 2 8 2.281412616569335 0.0225240421640218 1.8155339805825244 7.439320388349515 1.1233950947475233 0.2654033071264799 1.4295601388514203 1.5544197944414198 1.0052042080836443 0.2741718924063684 0.0076621340630544 0.0711332726649859 0.1375212864755611 0.0052676758380378 0.0336357980244025 +Glycoside catabolic process 4 6 2.281043646572487 0.0225458642616365 2.995145631067961 5.604368932038835 0.914408298188202 0.1915126053981477 1.4021397407455505 0.554137429771367 1.5051386650706404 0.245673751384095 8.614106390105149e-07 0.0385773062479974 0.0758460972151271 0.0007358710981923 1.3236156489067347e-05 +Mitochondrial fusion 7 14 2.2744134397752407 0.0229411401347248 5.730582524271845 14.140776699029129 0.9082040747396848 0.3521825448687026 2.97444400458197 2.016819417247653 1.0465735301082626 0.3054031781597867 0.0462334508798214 1.0 1.0 0.0329460998536745 0.012033886898071 +Response to steroid hormone 13 76 2.272520517527641 0.0230550901961725 13.225728155339803 70.58495145631068 0.1763568208377467 0.7136441197114008 5.741183042040811 6.972906426072971 0.6434426399957182 0.29607581376066 0.0484297102607875 0.0153171951263072 0.0434010576390882 0.021995802072265 0.0965183687527658 +Negative regulation of mrna metabolic process 18 47 2.271223014245213 0.0231334809060437 15.78640776699029 45.30339805825243 0.4317654752348391 0.5186468695555119 6.004287279655988 2.910090931551649 1.3207774317424965 0.3775544483756486 0.0038656850815872 1.0 1.0 0.008134640989773 3.703312293440564e-05 +Positive regulation of translation 19 60 2.270346756736221 0.0231865522324483 14.00485436893204 59.04854368932039 0.2226635785383083 0.671926467094376 6.74788537377648 3.7113801394297217 0.7891314904677239 0.3244977763908461 0.0112405353212617 0.4164957533300368 0.2898593955770666 0.0051500641348983 0.0002429495086324 +Vitamin transport 4 6 2.259587562671366 0.0238468602243262 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 0.0004524181434578 0.0060718409625537 0.0228441699597423 0.00251045639703 0.0052582215982291 +Respiratory chain complex iii assembly 2 6 2.255397830461188 0.0241083688073155 1.8470873786407769 5.160194174757281 1.360931378136811 0.1995688008303064 1.0650749835200868 1.2360161344522411 1.0120439004969468 0.2366879233397748 0.0010903561613953 0.0385773062479974 4.947049331965399e-05 0.0007358710981923 0.0053334351931861 +Ceramide transport 3 5 2.25394269505297 0.0241997732651513 1.779126213592233 5.310679611650485 0.994079753441996 0.2057455404068654 1.027416031856974 0.785538294365343 1.3065287972688011 0.2361222749942 0.0495722171873305 0.0619434524836269 0.1203280145079081 0.0388074443523606 0.0027834726260547 +Mitochondrial calcium ion transmembrane transport 2 8 2.237082108767195 0.0252809740697055 3.4684466019417477 9.04126213592233 0.7792467211325117 0.2463779000555085 2.196969341156949 1.2010296388602075 1.3738174116662032 0.263849842646199 0.3648807786147736 0.0756950383436983 0.1459927402947744 0.3269170707962712 0.039942155971048 +Amide transport 9 41 2.2369761981345486 0.02528789572249 9.512135922330096 37.99757281553398 0.8625203235532012 0.4243895840783888 3.9342099663331425 4.541875701235624 0.963016155404646 0.3369249994514658 0.0382164273134596 0.145012854682081 0.3899534463534457 0.1187596707915287 0.130362974035197 +Cellular response to oxygen levels 13 41 2.226482189265555 0.0259819006805457 8.393203883495145 36.271844660194176 0.9126927578207408 0.4163034805851183 3.607671495386698 4.048118764224637 0.9088125816374436 0.3418533733797396 0.3570191754856486 0.4135892767062017 0.0896229662502218 0.2707233824490334 0.0157503473184094 +Process utilizing autophagic mechanism 34 173 2.2245901727423845 0.0261087629585954 37.22330097087379 158.8252427184466 0.4533218180510577 0.6759877406594806 11.85403297791327 20.589929287102564 0.8897283418769861 0.36588075882003 0.0397202037584335 0.0632756056958945 0.1405284834996006 0.0413863748084201 0.0240298982774826 +Protein hydroxylation 6 17 2.217005139110325 0.0266227403528607 5.04126213592233 14.87621359223301 0.7765678108992397 0.4273021352291809 2.482119818897232 1.8660787070180411 0.9906439819977368 0.3285418073460514 0.0283422290577001 0.1114073342812727 0.0228441699597423 0.0199432580741765 0.0001037306954513 +Regulation of mitochondrial gene expression 2 11 2.2138853965494065 0.0268366635651935 2.594660194174758 11.4247572815534 0.8803116051858394 0.3443222138925089 2.2226265034531534 1.9350293365530056 0.991093358800792 0.2980671372776958 0.0385377758267946 0.1244478155008913 0.2339121686337894 0.0273244092926374 0.14168603717257 +Mucopolysaccharide metabolic process 3 8 2.2110641466580385 0.0270313953056091 3.400485436893204 8.912621359223301 0.5894446998893683 0.2689339883290864 1.6227448151896249 1.7256308603927724 1.433353391777711 0.275728271795533 0.1305066256361363 0.1988423464133734 0.0718258186813318 0.0966974979109908 0.1740747384317906 +Walking behavior 1 6 2.209372904345384 0.0271487140778783 1.5412621359223302 3.941747572815534 1.061808478348366 0.2641772565783438 0.940329605104622 0.948429900459882 1.1241511249150495 0.2684851276360596 0.0722227703866111 0.0756950383436983 0.1459927402947744 0.0569248849368824 0.1812716861639223 +Oxidative phosphorylation 14 61 2.200582895532219 0.0277655655714779 18.140776699029125 60.61893203883495 0.8137621380364766 0.3661293054253088 7.750013302753429 5.582386553809936 1.7413544544034578 0.3762713520958283 0.006074048444673 0.0204090903740193 0.0001614361869659 0.0025047398314607 0.0006338239940351 +Import across plasma membrane 9 16 2.20013744383272 0.0277971449731855 6.601941747572815 18.643203883495147 0.5666543433877399 0.4743790616320767 3.944616106748078 3.664494750162088 1.0498181035479843 0.3397186310535848 0.8849854045286951 1.0 1.0 0.8483368678739953 0.8905037759950227 +Cristae formation 7 9 2.196710715363136 0.0280411131007263 4.740291262135922 8.861650485436893 0.8982766043222677 0.3392698633906088 2.216011442046921 0.6593503673812457 1.2485531022675598 0.3418736408093433 0.327773653416176 1.0 1.0 1.0 0.0278921605814954 +Negative regulation of autophagy 8 24 2.186970929492938 0.0287446462529388 5.063106796116505 24.313106796116504 0.449887145270975 0.5377284095479077 2.9855473971181983 2.929018368027943 0.8516059018543028 0.3205218740462018 0.1173271790176747 0.2813938178053637 0.1400650262765533 0.0808304233724746 0.1064321965715116 +Female gamete generation 14 29 2.186539959989776 0.0287761244867965 6.050970873786408 23.531553398058257 -0.2581111968953511 0.6447931648531198 3.395431543719252 3.8756740114804744 0.6626649822495166 0.2711710124480643 0.645817652654681 0.3194831905047319 0.5377799970023095 0.5717749293752659 0.7385313534568869 +Response to ketone 10 42 2.184645414337292 0.0289148553531066 8.135922330097088 38.38592233009709 0.3161441476593932 0.5684563546193468 3.4607326899442756 4.1947836161356875 0.8306352296989162 0.3114696972884839 0.0101127074293734 0.0154102901166228 0.0208434347218513 0.0046057401193908 0.0147689868730135 +Regulation of lysosomal lumen ph 2 6 2.1823264520144856 0.0290854481089453 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 0.0076621340630544 0.0023758658868836 0.009201700056446 0.0052676758380378 0.0336357980244025 +Nucleotide transmembrane transport 5 8 2.181121283189916 0.0291744470344923 4.029126213592233 9.24271844660194 1.3657020532080593 0.1972377481261837 2.230443861436908 1.484326001257553 1.1744026177454787 0.2553979780962895 0.0008339442962802 0.0756950383436983 0.0004672463302539 0.0005013179159177 0.000745702459351 +Cell migration involved in sprouting angiogenesis 4 8 2.1771983199535376 0.0294657736144057 1.5024271844660195 7.502427184466019 0.6299354700552533 0.4033822961376643 1.5192914585292825 1.07599307575227 0.9565887314303816 0.280512597606792 0.2144776286214526 1.0 0.2636091346473535 0.1746199077901094 0.1897708582520546 +Tetrapyrrole metabolic process 8 21 2.177089847314041 0.0294738644210861 5.652912621359223 19.283980582524272 1.0342508202848784 0.290677507336007 2.6828141040028877 2.549402305664568 1.2308389507353266 0.2976223887279709 0.0013068267154036 0.0195557545343205 0.009062215893767 0.0219504556074559 0.0011157102419642 +Phospholipid metabolic process 30 81 2.1731111218548302 0.0297719548400816 18.805825242718445 74.80339805825243 -0.0109191555178773 0.4658808189502442 8.677118948764809 11.032066592781655 1.2956045948013235 0.3559409313369701 0.0999986177735189 0.717603602652989 0.2385776945731598 0.0933076787172633 0.0030102563556885 +Behavior 16 79 2.1717079615210206 0.0298776976365291 16.990291262135923 75.04126213592232 0.2909440827671418 0.5405324846032677 5.526186812971979 8.403983472903677 1.109438409605415 0.3578193814797769 0.2242719464258876 0.0427990140503725 0.049358292685713 0.2151961428428815 0.166068770722837 +Action potential 9 25 2.1654063311465936 0.0303565816350375 5.135922330097087 19.866504854368937 -0.0528859759829915 0.6260772890374331 2.550646381770937 2.366666661135001 0.8023128325713255 0.2900055567476459 0.0197042635512613 0.2412174988663298 0.4250358756773005 0.0474607851235824 0.0535493385180635 +Aminoglycan catabolic process 3 5 2.164770705403128 0.0304052492831685 2.6893203883495147 4.728155339805825 0.5164809724591738 0.1764823388548578 1.1619294817897845 0.7656988020633148 1.69808407883546 0.2279588459746903 0.0002477926457577 0.0573151884822011 0.0058956460302812 0.0026887292270871 0.0020033682110678 +Glycosaminoglycan catabolic process 3 5 2.164770705403128 0.0304052492831685 2.6432038834951457 4.665048543689321 0.5167433573606753 0.1777854895826483 1.1305026922003756 0.6751064263980151 1.6910244329591049 0.2288538535307848 0.0001688976199829 0.0526645480715484 0.0049445172385496 0.0020533662966424 0.00138858926748 +Intracellular transport 146 594 2.1639985721663253 0.0304644589860358 120.90291262135922 544.3956310679612 0.5500812282996078 0.6924011803517542 31.43517433849213 53.582766758854405 1.193070641867047 0.396756529943003 0.0001259226619123 0.0062993882829483 0.0187397054667065 0.0001525023635995 1.6456785971053003e-06 +Mitophagy 7 15 2.160515800898863 0.0307327617426145 4.174757281553398 14.737864077669904 0.7026339988268726 0.4220360300693995 2.5842209186951752 2.0501535109396865 0.9566781806577936 0.318538155650451 0.0546260884931124 0.141543756104335 0.2636091346473535 0.0391216296567294 0.0616223233666864 +Cellular respiration 25 105 2.1595635231719688 0.0308064747914749 27.975728155339805 102.1019417475728 0.3887198796668061 0.4496840882999475 12.70690482749566 7.191843824002275 1.6294784865611704 0.3894421445164553 0.0008406678472418 0.0003022541693841 1.5398870644954004e-05 0.0002164294346762 0.0003386551397025 +Metal ion transport 31 107 2.15106582050786 0.0314710048283053 24.868932038834952 99.21116504854368 0.6600358663497399 0.5322554902435589 9.162889792248723 11.473971032908404 1.1670714049066973 0.3920241658733104 0.1095588662255261 0.0902769364572717 0.2557400662576203 0.1448148344142252 0.12506497825261 +Protein catabolic process in the vacuole 4 8 2.144281632369548 0.0320103276222278 2.70873786407767 6.618932038834951 0.8383076008345888 0.2101105309103242 1.6017652153393662 1.88837291272598 1.5176899437744062 0.242508547144668 0.002032754568143 0.0042324529563037 0.0161297090986061 0.0012358112224234 0.002252196025852 +Lysosomal protein catabolic process 4 8 2.144281632369548 0.0320103276222278 2.6941747572815533 6.587378640776699 0.838918419522322 0.2080383809566978 1.5899151374262637 1.8707342212441815 1.5239608036504366 0.2420459791980847 0.0013416268925549 0.0034296220851759 0.0131546828557762 0.0008110696558398 0.0013491401517078 +Meiotic chromosome segregation 8 23 2.1423148114461887 0.0321681577582664 5.007281553398058 21.320388349514563 0.2019802860830169 0.6490546122321188 2.8297046722897017 2.442398917159905 0.7194362300409552 0.2944438752029195 0.1772632648430605 1.0 0.4017902994798545 0.3638889950068242 0.039409055534926 +Long chain fatty acid transport 7 15 2.1354558010344147 0.0327237968310194 3.4514563106796117 12.980582524271844 1.1347693444093316 0.300255043373995 1.9890654524939184 1.4909473272084874 0.7833838873177712 0.258106472565451 0.009238076730526 0.1373006943976843 0.2562935091164666 0.1658780833937837 0.0028128505043211 +Regulation of metal ion transport 17 63 2.1342504727821123 0.0328222830984987 11.844660194174756 53.10436893203884 0.1859078033323445 0.6922775588065759 4.935028907861149 6.572691395050338 0.699290754101615 0.3097288328014638 0.1092697016686659 0.2062582491875952 0.5055520121364779 0.0599911828080865 0.0407877490659717 +Proton transmembrane transport 18 40 2.134123042449311 0.0328327101329248 14.28640776699029 43.01699029126213 0.7821394801431882 0.3918912894345224 6.076814900000799 3.1076483585332 1.5710697941383835 0.3739424994204808 0.0047057665581292 0.010878638830109 0.0135552020851603 0.0020609914074487 0.0057738946985792 +Glycosyl compound catabolic process 5 10 2.1303434144091367 0.0331432717634838 3.216019417475728 9.74271844660194 -0.2866012386822237 0.2471021044870933 1.8641835401772064 0.9067280280460008 1.4904201092322935 0.2120144867281597 3.98283983100989e-05 0.1114073342812727 0.2108642126213972 0.00251045639703 0.0008169542553505 +Regulation of macroautophagy 16 61 2.125698576129037 0.0335283655768974 12.53883495145631 54.54368932038835 0.6601926076755246 0.5184966676512008 5.17189441564166 7.149617002477752 0.982640144191414 0.3711017134042489 0.0043008802684691 0.1399625708529587 0.0425585438658712 0.001620105919091 0.0007737853601128 +Regulation of sodium ion transport 8 18 2.1256079378034527 0.0335359181242755 4.859223300970874 16.485436893203882 0.2152863654464263 0.6142893159145967 2.876855649118466 2.4499418565317956 0.823622987865985 0.3141544887226273 0.1772632648430605 1.0 1.0 0.1335053000482259 0.2458770605062358 +Cellular ion homeostasis 20 87 2.124998429902329 0.0335867439091597 24.48543689320388 87.34708737864078 0.921352068115914 0.4223079442129951 9.212290310790763 8.933596252465952 1.5207794649628892 0.4002972861975121 0.0813530271094816 0.1493637558109807 0.2795885834804095 0.071348459153975 0.0253026863435532 +Regulation of cytoplasmic translation 8 15 2.1222814631438207 0.0338141091671591 5.116504854368932 15.155339805825244 0.0908372681199311 0.5771604615432117 2.8482696872209075 1.110473366688384 0.8718033181284137 0.3097683940138677 0.0283422290577001 1.0 1.0 0.0199432580741765 0.0008169542553505 +Protein insertion into mitochondrial inner membrane 3 7 2.12217973027577 0.0338226480290702 2.45873786407767 5.665048543689321 0.6692509200083531 0.3406754428009103 1.501050234026552 1.645659707056692 1.2686438529444872 0.3125184360343283 0.0002477926457577 1.0 1.0 0.0001472775053537 0.0020033682110678 +Prostate gland development 2 6 2.120948512820509 0.0339261354912936 1.6092233009708738 5.975728155339806 0.8122203292357496 0.3302673624761357 1.2128808594676108 0.7270055647304389 1.0647320376486975 0.2858771068016162 0.2144776286214526 0.141543756104335 0.2636091346473535 0.1746199077901094 0.1897708582520546 +Aminoglycan biosynthetic process 3 8 2.1189994844641284 0.034090510519013 3.0800970873786406 8.300970873786408 0.6387272076133388 0.2830924102482349 1.486473637192798 1.7113836533227735 1.3163721030030058 0.2655273000426038 0.1120171481403903 1.0 0.339526513295544 0.2737930251240831 0.1458719137718038 +Cellular response to inorganic substance 14 45 2.115007366926128 0.0344293194379567 8.021844660194175 38.55582524271845 0.3118217467450566 0.6862388564014436 3.7787099682845775 5.080353367472772 0.6826079048933258 0.3095344385107431 0.0491319229157538 0.4447949641299413 0.1115354306593847 0.0711465500702303 0.030012158607341 +Negative regulation of gliogenesis 1 6 2.1098128158951948 0.0348744821317388 1.3470873786407769 5.104368932038835 0.7908721225635217 0.3008340423028514 0.9967988871839628 1.1559387979758486 1.13650278668033 0.2567959459302846 0.1248348676040813 0.1026081339138497 0.1951188871774342 0.099708835751112 0.2906426697670494 +Glial cell proliferation 2 6 2.1082060819555317 0.0350131674374945 1.6262135922330097 5.412621359223301 1.1035845317400614 0.2421873681292294 1.0594430818589295 1.1842969002295405 1.0977939547178823 0.257309212646388 0.0253098881196153 0.0055832614279084 0.0210734332562196 0.017764157863851 0.0986013223955862 +Calcium ion transport 12 61 2.1063555732810144 0.0351734773242875 14.359223300970871 56.12135922330097 0.5117941214501432 0.5203785154770082 6.100858397237751 6.232924643281249 1.067298802513521 0.3756526252141436 0.2225199918724368 0.0549135737484113 0.2486707630168904 0.2605019777165379 0.0875458723455915 +Lysosomal lumen acidification 2 5 2.1042963182541343 0.0353526070277512 1.9077669902912624 4.094660194174757 1.0430284513288333 0.1731957374320673 1.0102570393282595 1.1504623937719378 1.495459416196642 0.2154807950267566 0.003018350944599 0.0012601973854463 0.0049445172385496 0.0020533662966424 0.0140894483762481 +Negative regulation of leukocyte mediated immunity 4 7 2.103460682353566 0.035425518745807 1.4684466019417477 5.152912621359223 1.0166590601943912 0.2872549002772236 1.1850502896064032 1.2860024091145663 0.9722873313503664 0.2687277537722931 0.1155282698604689 1.0 0.1871299927573601 0.0920739634299925 0.0171177319456962 +Intracellular protein transport 80 343 2.10223693918098 0.0355325254956528 72.23543689320388 320.84466019417476 0.4871189760263694 0.7214714639205947 20.45645165050656 29.914524602040487 1.0524664106682724 0.3751399671828122 0.000179099555747 0.2445894825879447 0.1345048371504613 0.0001332595484935 4.184811050378004e-05 +Negative regulation of exocytosis 2 8 2.098255401725518 0.0358825899284362 1.4344660194174756 7.218446601941747 0.625023241191846 0.4323785265344398 1.5897354168059734 1.070726780921098 0.8992776593749406 0.2947648575382397 0.0150287441417472 1.0 0.1709159600444602 0.0104402688493973 0.0621142898948071 +Fatty acid transport 8 19 2.096762600531501 0.0360145958244086 4.405339805825243 16.594660194174757 0.9956425124175664 0.363449355794835 2.458050105556273 1.867782713051167 0.7812672834370499 0.2834143639149277 0.0248070742612381 0.1788224008957527 0.3263246311566628 0.2555664496894125 0.0120719478590556 +Regulation of biomineralization 3 7 2.096675941666234 0.0360222716213161 2.0 7.254854368932039 0.7087493386381231 0.4293372114928327 1.648771240027478 1.7124900192906916 0.7924172542279996 0.2810900644904195 0.3596525601505327 0.1988423464133734 0.3588505448912167 0.3010844649684869 0.3756757272029017 +Respiratory electron transport chain 19 51 2.0957851964718186 0.0361012501375992 15.4126213592233 50.33495145631068 0.497076868891423 0.4388579749555677 7.129498131980449 4.223655269147207 1.4894225458303931 0.3736358875877055 0.0519555943862349 0.0115168854492305 0.0024792315325689 0.0298961619176513 0.0067623850268679 +Protein import into mitochondrial matrix 2 9 2.0906826163179533 0.0365565243152721 3.3276699029126213 9.03883495145631 1.4677455160780188 0.1396272549365287 1.9612536628062327 0.7162785445212654 1.2893924319512868 0.2212161399323651 0.0076621340630544 0.0711332726649859 0.009201700056446 0.0052676758380378 0.0336357980244025 +Purine nucleotide transport 5 8 2.089215266485224 0.0366883497889309 4.970873786407767 10.817961165048544 0.961055494000064 0.2880106547862709 2.8308505383502496 1.988649275322177 1.3314072021441097 0.3042395363852717 0.106411269870565 1.0 0.179062604831997 0.0846217526668656 0.0705348016344186 +Regulation of mrna splicing via spliceosome 23 67 2.0877312022142305 0.0368220885646828 20.90776699029126 63.19417475728155 -0.0284228947141631 0.5570393050560812 8.11843388838484 4.171815400572056 1.3006194329456693 0.3699711363352614 0.1034375451347237 1.0 0.5856426665825264 0.1727170115710306 2.2355633057585325e-05 +Regulation of membrane depolarization 2 12 2.0827228856342903 0.0372764901516782 2.516990291262136 7.686893203883495 0.0350478606542097 0.5368103099599445 1.9563694009351733 1.8385101234509107 0.9264070314419856 0.2972912730242556 0.0197997700033672 0.0981765691424607 0.1871299927573601 0.0138257504316944 0.0794376465838621 +Organic hydroxy compound metabolic process 28 119 2.074838285182629 0.0380015249965091 24.233009708737864 110.8883495145631 0.5334558429683288 0.4627633417898757 8.017219191403747 10.01417249072314 1.2419084217888356 0.3713800795527268 4.373648396339839e-07 0.0026489905210229 0.0019816599026893 7.015002299737224e-06 3.516487507718796e-06 +Transmission of nerve impulse 2 7 2.071306093155242 0.0383302002326368 1.6771844660194175 6.643203883495145 0.3619553328898606 0.5471795517105698 1.4330237685789071 0.8339736597924642 0.7570915834009635 0.2720943657720215 0.0722227703866111 0.0756950383436983 0.1459927402947744 0.0569248849368824 0.039942155971048 +Nerve development 1 9 2.0687364793128418 0.0385708220309204 1.5679611650485437 7.463592233009709 0.9323166733630548 0.322181793723066 1.371606215406715 1.1303984643014222 0.9327393846140116 0.2711478939504144 0.3494682964038688 0.1948770046367652 0.0690620672163432 0.2920005997725598 0.6384371778956772 +Regulation of bone mineralization 3 5 2.0670340180574085 0.0387309486101177 1.3325242718446602 5.320388349514563 0.7220419592899298 0.4163272640314809 1.2102356494008844 1.2730484187057145 0.8403168865039223 0.2764664272349757 0.2560967026301567 0.1583124314184509 0.2921659829416722 0.2102212619820596 0.2412627059282133 +Sterol transport 8 26 2.0657168689319896 0.0388552215249853 5.516990291262136 23.23058252427185 0.3564989162781894 0.4550431454343515 2.7566693478017315 3.339632072416373 1.1016145306573315 0.3225081354886266 0.0411708722095805 0.0437266531990119 0.1434310184114938 0.0843199651347959 0.0464752879206614 +Regulation of mitochondrial fusion 1 5 2.064336728236683 0.0389858009670591 1.5242718446601942 4.766990291262136 0.7253550907037913 0.367601169377127 1.0824698493002796 0.7815081697098348 1.0008486659137603 0.2877626014609443 0.0302121860941904 1.0 1.0 0.0234889728544392 0.0820486275159116 +Amino acid transmembrane transport 8 14 2.0618870640806186 0.0392184893924347 6.213592233009709 14.228155339805824 0.7890307267204019 0.3318923540291705 3.493823914060917 1.9561661273054285 1.3497309258640615 0.3227865040448734 0.7369784325455169 0.2067156970649581 0.3714211816154574 0.6879878545074485 0.4023686447738411 +Crd mediated mrna stabilization 5 9 2.052288395368553 0.0401416431279491 3.20873786407767 8.672330097087379 0.342620078434644 0.5402296309994439 1.975608879775515 0.4994282243026395 0.8747796830448701 0.31559390711261 0.0246179943383446 1.0 1.0 0.0190953097419897 0.0005732271800539 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 5 9 2.052288395368553 0.0401416431279491 3.2305825242718447 8.737864077669903 0.3383340983010549 0.5432346157858564 2.00913850312594 0.5653620722928415 0.8709422947456378 0.3151834351252267 0.0427179386115036 1.0 1.0 0.0333651833289618 0.0020033682110678 +Peptidyl proline hydroxylation 3 8 2.048295883020132 0.0405310161540519 2.9393203883495147 7.366504854368932 0.8317722887875127 0.3653030215718857 1.5036226559632782 0.8268224457358132 1.022007383809078 0.3112189596123257 0.0427179386115036 0.0573151884822011 0.0058956460302812 0.0333651833289618 0.0020033682110678 +Nucleobase containing compound transport 28 105 2.0458003519408594 0.0407760174060041 27.29368932038835 106.8616504854369 0.0529116637722391 0.7296488875237338 10.770269172095956 7.4844683965402945 0.8451319935554741 0.3201418496364633 0.2144132130619767 0.2098528472852485 0.0280658759742037 0.133905650813 0.0224162027378251 +Multicellular organismal signaling 9 28 2.034170600223971 0.041934397675996 5.87621359223301 23.368932038834952 0.1251561677633836 0.5743186573384436 2.8543472606666915 2.0644484501067764 0.8949922760766115 0.315421651584248 0.0274480195124167 0.0358926009784828 0.1202677732034906 0.0614665248433369 0.0278547210480151 +Homologous chromosome segregation 6 11 2.0341108751804367 0.0419404177274085 2.9441747572815533 9.983009708737864 0.8658101820521615 0.3886675393312038 1.6544409340956687 1.448870557748215 0.8756753907408087 0.3062582021532934 0.0462334508798214 1.0 0.2489059409173845 0.157217223036351 0.012033886898071 +Positive regulation of macroautophagy 9 24 2.033437637468661 0.0420083280685921 5.058252427184466 20.34223300970874 0.7197293510270528 0.4154159089925248 2.5734840677494253 3.836065802213299 1.0387053871978371 0.3265560923975395 0.0257659124026122 0.2560754722464486 0.0209290225413289 0.0153040129106345 0.0022883393024557 +Female meiotic nuclear division 7 12 2.032490978467904 0.0421039761627255 3.3567961165048543 8.978155339805825 -0.1611926367727561 0.587587410275829 2.1124635751865104 1.860944664365577 0.752675862250315 0.2695463962292129 1.0 1.0 1.0 1.0 0.712992529293242 +Protein transmembrane transport 9 25 2.0291916313978344 0.0424387756247857 8.992718446601941 25.191747572815533 1.6893060623430327 0.189108476986505 4.473486660459625 2.7693940759543416 1.4682653164365471 0.2783169275392022 0.0034468330488433 0.027703186905031 0.0150469902773183 0.0017538141840637 0.0136894768366188 +Positive regulation of cytoplasmic translation 6 11 2.0285888850578653 0.0425001816093812 3.8859223300970873 11.201456310679612 0.2152733002107591 0.5436996741605163 2.279945467280569 0.7540813323894404 0.8728322548085549 0.2996316994321754 0.0495722171873305 1.0 1.0 0.0388074443523606 0.0027834726260547 +Positive regulation of autophagy 10 34 2.0281053088503675 0.0425495012121275 7.036407766990291 30.483009708737864 0.6693528554580194 0.4628135853102879 3.235293043364778 5.784747493453153 0.9361869896860724 0.333658419297932 0.0936066104275255 0.4251307382490726 0.0973635670841622 0.1389075487348322 0.0458044806843984 +Lipoprotein localization 2 8 2.027646835577552 0.0425963052739306 1.7451456310679612 4.762135922330097 1.33870340128666 0.2150435313503844 1.1193794779630346 1.3835803073772095 0.999398972942542 0.2555578059866495 0.0039418703774766 1.0 0.0058956460302812 0.0026887292270871 0.0181181417645757 +Regulation of cell migration involved in sprouting angiogenesis 3 5 2.0225819377517875 0.0431162679677705 0.8398058252427184 4.225728155339806 0.7178102037241717 0.3667185464430539 0.9647012521944212 0.847622720091341 1.0176197124784383 0.2809389006419704 0.1248348676040813 1.0 0.1951188871774342 0.099708835751112 0.0888008652079453 +Regulation of lipase activity 5 12 2.022463097036707 0.0431285322855186 3.262135922330097 11.20873786407767 0.5080857493577803 0.3640362286084045 2.107366483573331 1.390020380944142 1.1722840995258883 0.3007278087276755 0.1003001736992858 0.1788224008957527 0.3263246311566628 0.0734338910721259 0.1281606076495765 +Selective autophagy 10 30 2.022061551382027 0.0431699934606921 7.861650485436893 28.031553398058257 0.6116968756419903 0.5194450063363468 3.450451665126401 4.3159755745103565 0.9002253779314615 0.3454803983634653 0.2882906612121324 0.2813938178053637 0.4844502219581325 0.2245115961783209 0.0155196297710904 +Positive regulation of mitochondrion organization 8 23 2.020330357282426 0.0433491319464374 6.235436893203883 22.393203883495147 0.6669540243221574 0.4355223453199826 2.7589935116766484 2.962672702300372 1.01251720769805 0.3295170825531805 0.0158315531323641 0.2298835505782255 0.0951370618475993 0.0092216123798009 0.0426924060067812 +Nervous system process 26 110 2.0173794688212494 0.043655928170095 23.060679611650485 100.46844660194176 0.466210961761844 0.5050785047376438 7.1617042179301365 12.55034423055404 1.1784062094355452 0.368401069133876 0.4773493663773748 0.3261916081227893 0.3753400975093728 0.3008431973730953 0.2678028925382042 +Lipid homeostasis 10 27 2.0152033040390824 0.0438833514856167 7.665048543689321 25.939320388349515 0.8425417577103904 0.3366972259521467 2.992619034719237 3.7336969269092393 1.1648658675422845 0.295769208633365 0.0084107251134957 1.0 0.195637464602177 0.0521205227118809 0.0021782131622251 +Protein containing complex localization 17 50 2.014235541222838 0.0439848098613913 10.444174757281552 42.963592233009706 -0.0116153883479753 0.7670638185904641 4.810414475465765 5.508258117064915 0.5374525581408421 0.2588999426869024 0.6836661753150602 0.4611241633653626 0.3476177217996948 0.5927846079291184 0.0831023586543636 +Maintenance of location 16 74 2.008127342443608 0.0446297614094766 14.529126213592232 67.10194174757281 0.2761251361558006 0.5437230382448518 5.781761264023897 6.826866977938762 1.0069098531292424 0.349986956897805 0.1058873127428175 0.0736360802948869 0.0458171134049685 0.1144375788093372 0.0170542901938563 +Mitochondrial cytochrome c oxidase assembly 1 5 2.00732326800549 0.0447152531806738 2.344660194174758 5.764563106796117 0.9954600272926416 0.2681565835601643 1.449018962088891 1.4364892997002987 1.2150903662861117 0.2820677765861404 0.1248348676040813 0.1026081339138497 0.1951188871774342 0.099708835751112 0.2906426697670494 +Modification of synaptic structure 3 8 2.004945571164101 0.044968866131587 1.9902912621359223 8.087378640776699 0.8554193794108192 0.3851394739224027 1.562579058231813 0.6625457832358376 0.856660193170285 0.2984698193580089 0.0975023582906358 1.0 1.0 0.0773660358903978 0.0119688845689888 +2 oxoglutarate metabolic process 1 10 2.0007590642334443 0.0454183608663989 3.453883495145631 9.264563106796116 -0.1064110443111423 0.384612626342152 2.2992842841711263 0.7004898101848963 1.2698803823360194 0.3050485324830972 0.0643496578587389 0.0023758658868836 0.009201700056446 0.0506052248933858 0.16360549489043 +Homologous chromosome pairing at meiosis 3 8 2.000740068439124 0.0454204089956926 2.4975728155339807 8.245145631067961 0.965829654578573 0.3348869860078453 1.4047402178514554 0.97323438747629 0.9242483632276672 0.2995534430572119 0.0173221540664081 1.0 0.179062604831997 0.0846217526668656 0.01439805670462 +Response to corticosteroid 7 31 1.994300799149338 0.0461191919742538 5.691747572815534 27.075242718446603 0.4079678667256687 0.5657392437937305 3.009633376757725 2.449820419279508 0.8211557550622286 0.3160966272616047 0.0728990895622241 0.0584635742500571 0.1849845964283991 0.0457163514521504 0.040110502552073 +Peptidyl glutamic acid modification 1 5 1.99142496981876 0.0464341863574679 1.2766990291262137 4.783980582524272 0.5726285862666396 0.4410327304183206 1.015004317126516 0.8299231919143666 0.9676219991614484 0.3116400575480735 0.0567913213537204 0.066549445548378 0.1289666473793992 0.0445602183527292 0.1462762019757018 +Calcium ion import 3 13 1.9871067467421075 0.0469105687556674 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 0.083729479939788 0.0140700862732742 0.0507931717892238 0.2282899009392132 0.1034478004905659 +Negative regulation of macroautophagy 4 10 1.9843825930705448 0.0472132050361453 2.657766990291262 11.342233009708735 0.5734063046472396 0.4235310399182105 1.9797182461289764 1.5349845399675808 0.9579244223739132 0.2955499758703153 0.2144776286214526 1.0 0.2636091346473535 0.1746199077901094 0.0616223233666864 +Organic hydroxy compound biosynthetic process 21 55 1.9821719127030832 0.047460003117888 12.42233009708738 52.37135922330097 0.7934054609743442 0.424605725297311 4.713262264354627 5.1877801804871915 1.1130427360157376 0.3580104692277669 0.0002956626933664 0.1349531687426338 0.0092324336297151 0.0013655868178279 1.7672426250278156e-05 +Localization within membrane 33 191 1.977104311667406 0.048029840519159 43.83252427184466 179.48543689320388 0.7329824809593914 0.5973922945503244 12.803162929787796 21.32668417309247 1.133148805830878 0.4087008058998355 0.0043531594084067 0.2100884614225742 0.1939293408487501 0.026935498173655 0.0112387704937969 +Neuronal action potential 2 5 1.97149459444928 0.0486673306987524 1.2475728155339805 4.521844660194175 0.5642353900817267 0.463764525154269 1.1328582855694418 0.6169203935566157 0.8757196856996938 0.2995166866793592 0.0073631413049259 0.0242848323540905 0.0480955538847994 0.0056579443580751 0.0010631590368518 +Hormone biosynthetic process 5 10 1.9706863671928767 0.0487597608429171 3.2766990291262137 8.762135922330097 0.5893833627772115 0.3611309387757575 1.7820956292372838 1.0801489024333786 1.1172063688590312 0.2892911953740955 0.005499153241604 0.007105321595433 0.0265618978442646 0.0247234076565489 0.0353483729682259 +Low density lipoprotein particle clearance 4 10 1.9704688001746076 0.0487846673121785 2.628640776699029 10.633495145631068 0.2652848599989675 0.2775304047094778 1.52978680445189 1.394909057645927 1.3932465899654711 0.2286950604253255 0.0092378701630156 1.0 0.1459927402947744 0.0569248849368824 0.000745702459351 +Alcohol biosynthetic process 12 37 1.9689643675981705 0.0489571830194517 9.344660194174756 36.09466019417476 1.0726679306851277 0.3539682718575088 3.792896481514287 3.1078151772256564 1.1587776417647702 0.3419459456532639 0.0001637357564003 0.0691107257825923 0.0016898291272514 0.0002844112557687 8.056907748559596e-05 +Maintenance of protein localization in organelle 8 19 1.9667470874923212 0.0492123754014013 3.866504854368932 15.29368932038835 0.5637691386290394 0.4400793840085654 2.3676920099244176 1.9777055894707407 0.9564449590017818 0.2977236914910925 0.0129229397102748 0.0112943240362007 0.0040346592713098 0.0081443152876 0.0046379242911556 +Rhythmic process 21 65 1.9603763838926704 0.0499518140601427 14.072815533980584 58.800970873786405 -0.061501078600924 0.722634761384288 6.863406470802091 5.410274209184701 0.6164406885244239 0.2746499488830534 0.2854478360650835 0.5451422660923099 0.0708670341065168 0.1933758801380208 0.3691737175715215 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..258fe98f004cc9f4e76194a079af6dc33b4fcc86 --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 6562, + "title": "Average number of proteins per term", + "value": 20.488722950320025 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c05dcd7af4eea629327211e7cc5ffef7acc1cc93 --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..afb3a281461989322fcb17c6f83f429ba923c5e8 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,2017 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transmembrane transport 0.5199665900084476 5.9351433053270926 2.935889480170374e-09 1.9265121228889004e-05 1.926530677544e-05 213 Q99623,P52789,Q9NS69,P21796,P51798,Q7KZN9,Q9UBX3,P45880,Q70HW3,O60830,Q9H0U3,Q9C0H2,Q9Y6M7,P00403,Q9UGP8,P04062,O75844,P23786,Q9HD20,Q96ES6,L0R6Q1,Q9Y619,Q9H2V7,O75964,Q9H2D1,P28288,Q8TB61,Q9UHG3,O43615,Q9BSK2,Q6NUK1,P55011,O43808,Q9UDW1,Q99595,Q9BXP2,Q99523,Q6P4Q7,P05023,P46934,Q9HD47,Q14BN4,Q15629,Q07820,Q9Y584,P38435,P24539,Q13423,Q9BQT8,P08183,Q4KMQ2,Q8WTV0,Q96GC9,Q15043,Q06787,O14925,P05067,Q96PU5,Q03519,Q00325,P12235,Q03518,Q6P4A7,O14678,P16615,P53985,Q99797,P08574,Q9Y277,P13073,Q16625,Q8IYU8,P14854,P20020,P30825,O95202,Q96NB2,O95831,P12236,Q8NE01,P42858,Q9BZF1,O43772,O43865,Q9NUT2 85 +Mitochondrion organization 0.4924332276574115 5.405420166859042 6.465664462886018e-08 0.0004241869230544 0.0002121384510305 200 Q99623,P30536,P52789,Q9NS69,O14965,P21796,Q69YU5,Q9H061,P45880,O95168,Q9Y2R0,O60830,O43676,P04062,Q16706,Q9UDX5,Q9Y5Z4,Q9Y2S7,Q9Y5J7,Q13505,O43615,Q9BSK2,P14406,P55786,P03886,Q99595,Q6DKK2,Q5JRX3,Q9NVH1,Q96A26,Q9BUR5,P78310,Q8N4H5,O96000,Q5XKP0,Q9Y584,Q9Y5L4,O75153,Q8NAN2,Q9Y6C9,Q9UBN7,Q9P0J0,P07900,Q8N2A8,O14737,Q86Y39,O75438,P49257,Q15070,Q6UXV4,Q9Y5J9,P51572,O14925,Q9NX63,Q7Z3C6,P12235,Q9P032,Q16543,Q9H4A6,P05141,Q5T9A4,Q96CU9,Q9Y512,Q14457,Q99797,Q10713,Q9Y6M9,Q96RL7,O60313,P51970,Q8TB36,O95202,O95831,O75306,Q9NVI7,P42858,Q9NUQ9,Q7L592,Q9UG56,Q16891,Q9NQG6,P27544 82 +Anion transport 0.6365543853155646 4.817090102378592 1.4566692139172943e-06 0.009513131466816 0.0031862211272439 67 P30536,Q9NP80,P21796,P51798,Q9UBX3,P45880,P53985,P30825,Q15907,P04083,Q9C0H2,Q96NB2,Q9Y6M7,Q9BQT8,P08183,P12236,Q4KMQ2,P07602,P11166,Q9Y619,Q9H2D1,P28288,Q9UJS0,O43681,Q9Y277,Q8TB61,Q9UHG3,Q15043,Q6NUK1,O75746,Q02978,P55011,O43808,Q15041,Q9NZJ7,Q9BXP2,Q00325,P12235,O43865,P05141,Q14728 41 +Organic anion transport 0.6990465558997867 4.739580566015254 2.141610703887409e-06 0.0139549783183873 0.0035133123597289 43 Q9NP80,Q9UBX3,P53985,P30825,P04083,Q96NB2,Q9Y6M7,Q9BQT8,P12236,P07602,P11166,Q9Y619,Q9H2D1,P28288,Q9UJS0,Q8TB61,Q6NUK1,O75746,Q02978,P55011,O43808,Q15041,Q9NZJ7,P12235,P05141,Q14728 26 +Membrane lipid metabolic process 0.7580166056606268 4.664584304398999 3.092415346017674e-06 0.0200879545410657 0.00362513225766 37 Q06136,P06865,O60512,P06280,P50897,P04062,O15269,P07602,Q9P035,O15270,P16278,P22059,O43292,P17900,Q9NZJ7,O95470,Q8NCC3,Q8NBX0,Q13510,Q96G23 20 +Anion transmembrane transport 0.7219496388381396 4.640049919367094 3.48325025845142e-06 0.0225978828109596 0.00362513225766 40 P21796,P51798,Q9UBX3,P45880,P53985,P30825,Q96NB2,Q9Y6M7,Q9BQT8,P08183,P12236,Q4KMQ2,Q9Y619,Q9H2D1,Q9UJS0,Q9Y277,Q8TB61,Q9UHG3,O75746,Q02978,P55011,O43808,Q15041,Q9BXP2,Q00325,P12235,Q14728 27 +Ion transmembrane transport 0.4892365086350674 4.618400013374302 3.867102377874687e-06 0.0250567110636117 0.00362513225766 154 Q99623,O75027,P20020,P27695,P21796,P24539,P51798,Q7KZN9,Q9UBX3,P45880,Q70HW3,P16615,Q13423,Q9UM00,P53985,P30825,P31930,O95202,Q9H0U3,Q9C0H2,Q96NB2,Q9Y6M7,P00403,Q9BQT8,O75844,P08183,P12236,Q9HD20,Q4KMQ2,Q96ES6,P06576,P08574,Q9Y619,O75964,Q9H2D1,Q9UJS0,Q9Y277,Q8TB61,Q9UHG3,Q96GC9,Q15043,O75746,P42858,P55011,Q02978,O43808,Q9UDW1,Q06787,P05067,Q15041,P13073,Q96PU5,Q9BXP2,Q6P4Q7,Q00325,P12235,O43772,P56385,Q8IYU8,O43865,P05023,P46934,Q9HD47,Q6P4A7,P05141,P14854,Q14BN4,Q9NUT2,Q14728 69 +Ion transport 0.4430630018281624 4.582058119795409 4.604218803772042e-06 0.0297611040701019 0.0037766104737948 210 Q99623,P30536,P21796,P51798,Q7KZN9,Q9UBX3,P45880,Q70HW3,Q9H0U3,Q9C0H2,Q9Y6M7,P00403,O75844,Q9HD20,Q96ES6,P07602,Q9Y619,O75964,Q9H2D1,P28288,O43681,Q8TB61,Q9UHG3,Q6NUK1,P55011,O43808,Q99959,Q9UDW1,Q9BXP2,Q6P4Q7,O15173,P05023,P46934,Q9HD47,O14936,Q14BN4,Q14728,P24539,Q13423,Q9UM00,P04083,Q9BQT8,P08183,Q4KMQ2,P11166,P06576,Q9UJS0,Q96GC9,Q15043,O75746,Q02978,Q06787,P05067,Q15041,Q96PU5,Q00325,P12235,P56385,Q6P4A7,P05141,Q9UHQ9,O75027,P27695,Q9NP80,Q96S66,P16615,P53985,Q15907,P31930,P08574,Q9Y277,P61586,Q9NZJ7,P13073,Q8IYU8,P14854,P20020,P30825,O95202,Q96NB2,P12236,P33176,Q8NE01,P42858,O43772,O43865,O76024,Q9NUT2 88 +Lipid metabolic process 0.4032014367976548 4.546397592058179 5.457190360935726e-06 0.0351765819462753 0.0039788981276074 294 Q9BQE5,Q99623,O75874,P30536,P61916,O60512,Q16134,P50897,Q15392,Q8NCG7,Q14849,P04062,O75844,P23786,P07602,Q9HB40,Q96SU4,P16278,P28288,O95864,O43681,Q8NHP8,A1L0T0,O75477,Q6IAN0,P17900,O43808,P54646,Q9BTU6,Q9NWU1,Q9NXE4,Q86UY6,O95470,Q15800,Q8NCC3,Q9NPH0,Q8NBX0,P05023,O60762,P51648,Q9UBM7,O15118,Q14534,Q16836,Q9H490,Q96G23,P38435,P07099,Q06520,P04083,O14773,Q8N2A8,P37268,Q8WTV0,Q96N66,O43292,P05067,Q16850,Q6NUM9,Q14739,P52429,P16435,Q8TBX8,Q13510,P35610,Q06136,O14678,Q53GQ0,Q9NP80,P53985,P06865,P06280,Q96K12,P21964,O15254,Q14457,Q2TAA5,O15269,Q10713,Q9P035,O15270,Q9BWD1,O15228,P22059,Q15067,Q2T9J0,Q15118,Q9NZJ7,Q99519,A8MXV4,P42345,P48651,Q9NUQ2,O76062,Q15120,Q9UBV2,O14734,Q13315,O14975,P46108,Q86YN1,Q9BZF1,Q709F0,O75845,Q9H7Z7,Q9UG56,Q8N4Q0,Q9BT22,P27544,Q8NF37 110 +Mitochondrial transport 0.5313885517592211 4.400740742225707 1.0788196088018507e-05 0.0683448323871234 0.0070792142729584 85 P30536,Q9NS69,P24539,Q9UBX3,P45880,O60830,Q9Y512,Q14849,Q9P0J0,P23786,Q99797,O14737,O75964,Q9Y5Z4,Q15070,Q9Y5J9,O14925,Q99595,Q5JRX3,P12235,Q8N4H5,Q9Y584,Q9Y5L4 23 +Sphingolipid metabolic process 0.8071452068133409 4.317123674310834 1.5807559760716572e-05 0.0985313632457031 0.0088417285946373 28 Q06136,O15269,P17900,P07602,Q9P035,O15270,P16278,Q9NZJ7,P06865,O60512,P06280,P50897,O95470,Q13510,Q8NCC3,P22059,Q96G23,P04062 18 +Lipid localization 0.5306558230598136 4.312129552517813 1.61689642084184e-05 0.1006667296486936 0.0088417285946373 80 Q9BQE5,P30536,O14678,P61916,Q9NP80,P04083,Q99720,Q14849,P04062,P23786,P08183,Q4KMQ2,P07602,O14975,Q8WTV0,Q96SU4,Q9H2V7,P28288,Q14108,P22059,Q96GC9,P17900,O43808,Q9BZF1,Q9NZJ7,O43772,O15260,O15118,Q14534,P35610 30 +Organic acid transport 0.6310083675585713 4.276004080506537 1.902777366802333e-05 0.117380809052622 0.0096046346776596 46 O14678,Q9NP80,Q9UBX3,P53985,P30825,P04083,Q96NB2,Q9BQT8,P08183,P23786,P11166,O14975,Q9Y619,Q9H2D1,P28288,Q9UJS0,O75746,Q02978,P55011,O43808,O43772,Q6P4A7 22 +Secondary alcohol metabolic process 0.6202767997888998 4.178061269188547 2.9400446481586684e-05 0.1754591276451761 0.0100672309125257 46 Q9BQE5,O75874,P37268,P16435,Q8WTV0,P48735,P54646,P05067,O15118,Q06520,Q16850,Q15392,Q15800,Q14534,Q14849,Q14739,P04062 17 +Mitochondrial transmembrane transport 0.6043024166311047 4.1060593282741715 4.024661523116535e-05 0.2321060212146654 0.0100672309125257 51 P21796,P24539,O60830,O95202,Q96NB2,Q9BQT8,O95831,P23786,P12236,P06576,Q9Y619,O75964,Q9H2D1,Q9UJS0,O43615,Q9BSK2,O75746,O14925,Q99595,Q00325,P12235,O43772,Q8IYU8,P56385,Q6P4A7,P05141,Q9NUT2 27 +Steroid metabolic process 0.5304968339264583 3.859054123127185 0.0001138267292912 0.5262016696371304 0.0100672309125257 71 Q9BQE5,P30536,Q53GQ0,P61916,P38435,O14734,Q06520,Q15392,Q14849,P04062,P37268,O14975,Q8WTV0,Q96SU4,P28288,O75477,P22059,P54646,P05067,Q16850,O75845,O95470,Q15800,Q14739,P05023,P16435,Q14534,O15118,Q13510,P35610,O76062 31 +Mitochondrial respiratory chain complex assembly 0.6335888534660037 3.8292633894629735 0.0001285273901487 0.5697767154156503 0.0100672309125257 39 O75306,P51970,Q9Y6M9,Q86Y39,P03886,Q69YU5,Q96CU9,Q9H061,Q6DKK2,Q9Y2R0,O43676,Q9Y512,Q15070,Q7L592,Q9BSK2,Q9P0J0,O95831 17 +Lipid biosynthetic process 0.436568819432693 3.788227312375687 0.0001517260006573 0.6305358458717815 0.0100672309125257 154 P30536,O75874,Q06136,O76062,Q53GQ0,Q9NP80,O14734,O00767,Q13315,O60512,Q8NCG7,Q15392,P04083,Q14849,P04062,Q14457,O15269,Q10713,P37268,Q9P035,O14975,Q8WTV0,Q96SU4,O15270,P28288,O95864,O15228,O75477,Q96N66,P22059,Q6IAN0,O43292,Q86YN1,P54646,Q9BTU6,Q9NWU1,Q9NXE4,Q16850,O75845,O95470,Q9H7Z7,Q15800,Q8NCC3,Q9NPH0,Q14739,Q8NBX0,Q9UG56,P42345,P52429,P05023,P16435,O60762,P48651,Q13510,Q9NUQ2,Q9UBM7,Q8TBX8,P27544,Q8NF37,Q14534,Q9H490,P35610,Q96G23,Q9NZ01 64 +Cellular lipid metabolic process 0.3978304310710938 3.7705381423416786 0.0001628959021915 0.6566517295533401 0.0100672309125257 221 Q99623,O75874,P61916,O60512,Q16134,P50897,Q8NCG7,P04062,O75844,P23786,P07602,Q9HB40,P16278,P28288,O95864,Q8NHP8,A1L0T0,O75477,Q6IAN0,P17900,O43808,P54646,Q9BTU6,Q9NWU1,O95470,Q15800,Q8NCC3,Q9NPH0,Q8NBX0,P51648,Q96G23,P07099,P04083,P37268,Q8WTV0,Q96N66,O43292,Q6NUM9,P52429,P16435,Q8TBX8,Q13510,P35610,Q06136,O14678,Q53GQ0,Q9NP80,P06865,P06280,O15254,Q14457,Q2TAA5,O15269,Q10713,Q9P035,O15270,Q9BWD1,O15228,P22059,Q15067,Q2T9J0,Q15118,Q9NZJ7,Q99519,A8MXV4,P48651,Q9NUQ2,Q15120,Q9UBV2,O14734,Q13315,O14975,Q86YN1,Q9BZF1,Q709F0,Q9H7Z7,Q9UG56,Q8N4Q0,Q9BT22,P27544,Q8NF37 81 +Sterol metabolic process 0.5978760645834117 3.763513396669183 0.0001675427471452 0.6669649757493641 0.0100672309125257 42 Q9BQE5,P37268,P16435,Q8WTV0,P54646,P05067,O15118,Q06520,Q16850,Q15392,Q15800,Q14534,Q14849,Q14739,P04062 15 +Carboxylic acid transport 0.6784267032652515 3.750825452438684 0.0001762533685396 0.6854702275738436 0.0100672309125257 32 O75746,Q02978,P55011,P07602,Q9NP80,Q9UBX3,Q9Y619,Q9NZJ7,P53985,Q9H2D1,P28288,Q9UJS0,P30825,P04083,Q96NB2,Q9BQT8 16 +Cation transmembrane transport 0.4562536729082958 3.7384087398997186 0.0001851886918264 0.7033851345660687 0.0100672309125257 120 Q99623,P20020,P21796,P24539,Q7KZN9,P16615,Q70HW3,Q13423,P30825,O95202,Q9H0U3,Q96NB2,Q9Y6M7,P00403,Q9HD20,Q4KMQ2,Q96ES6,P08574,Q9Y619,O75964,Q96GC9,Q15043,P42858,P55011,Q9UDW1,Q06787,P05067,P13073,Q96PU5,Q9BXP2,Q6P4Q7,Q00325,P12235,O43772,Q8IYU8,P05023,P46934,Q9HD47,P14854,Q9NUT2 40 +Mitochondrial membrane organization 0.558345406978822 3.6429675313679177 0.0002695128454108 0.8294593606980036 0.0107135640827163 50 P52789,Q9NS69,P45880,Q9Y512,O95202,Q9P0J0,P07900,O14737,Q9Y5Z4,Q15070,Q9Y5J7,Q13505,Q6UXV4,Q9Y5J9,Q9NX63,P12235,Q9NVH1,Q9BUR5,Q16891,P05141,Q9Y5L4,Q5XKP0,Q9Y584,O60313 24 +Organic acid transmembrane transport 0.6944710293826817 3.63706619265532 0.0002757610836936 0.8363121106361686 0.0107135640827163 29 O75746,P08183,P23786,Q02978,O14678,P11166,Q9UBX3,Q9Y619,P53985,Q9H2D1,P28288,Q9UJS0,P30825,O43772,Q96NB2,Q9BQT8 16 +Membrane organization 0.3896601172725247 3.6340439034264977 0.000279013352638 0.8397693738738419 0.0107135640827163 227 P46379,P30536,Q9P2W9,P57088,P52789,P49354,P61916,Q9NS69,P45880,P16615,Q9UQB8,Q9HCU5,P50897,Q15392,P04083,Q9ULX6,Q9Y512,Q14849,O95202,Q9P0J0,P07900,Q13190,O75844,P08183,Q86XL3,Q4KMQ2,O14737,Q14457,Q13277,O95249,Q9UH99,P50402,Q9Y5Z4,O15228,O43681,Q15070,Q9Y5J7,Q8NHH9,Q13505,P22059,Q6UXV4,Q96GC9,Q9Y5J9,Q9NPA0,Q9BZF1,P61586,Q15041,Q9NZJ7,Q8NFQ8,Q9NX63,Q7Z3C6,P12235,Q8N1F7,Q9NVH1,Q9BUR5,Q9H4A6,Q9NQC3,Q16891,Q96A33,P05141,O15118,O94901,Q5XKP0,Q15629,P53350,Q08431,Q9Y584,O60313,O95487,Q9Y5L4 70 +Inorganic ion transmembrane transport 0.453536530929071 3.633884258549123 0.0002791861411375 0.8399509971737843 0.0107135640827163 115 Q99623,O75027,P20020,P27695,P21796,P24539,P51798,Q9UBX3,Q7KZN9,P16615,Q13423,Q9UM00,O95202,P31930,Q9H0U3,Q9Y6M7,P00403,Q9HD20,Q4KMQ2,Q96ES6,P06576,P08574,O75964,Q9UHG3,Q96GC9,Q15043,P42858,P55011,Q02978,Q9UDW1,Q06787,P13073,Q96PU5,Q9BXP2,Q6P4Q7,Q00325,P12235,P56385,Q8IYU8,P05023,P46934,Q9HD47,P05141,P14854,Q14BN4,Q9NUT2 46 +Vacuole organization 0.5460697320040754 3.5655794785391413 0.00036305311421 0.9077070111452602 0.0117357366278139 53 P42345,O14773,O75503,Q96GC9,P16615,Q8TBX8,P50897,P04062,P10253,Q8N511,P54802,Q14108,Q14457 13 +Glycoprotein biosynthetic process 0.5387672596695904 3.525035649695188 0.0004234258041038 0.9379061631906682 0.0119461746959582 55 Q7LGA3,O14734,O60512,O60502,Q9H0U3,Q2TAA5,Q16706,Q8N4A0,P46977,Q9Y287,Q86YN1,Q10472,Q9UL01,Q96L58,Q9NQX7,Q92542,O60476,O60762,Q6ZXV5,Q9BT22,P04844,O15118,Q8NAT1,P35610,O60568 25 +Protein targeting to mitochondrion 0.5486106816605889 3.4982384098727923 0.0004683422728035 0.9537633214641752 0.0129128655215841 46 P30536,Q99797,Q9Y5J9,Q10713,O14737,Q8TB36,Q9NS69,Q8N4H5,O14925,Q99595,O60830,Q9Y512,Q5JRX3,Q9Y584,Q9Y5L4,Q9P0J0 16 +Protein localization to mitochondrion 0.5297101838223477 3.4907346241274455 0.0004816944556416 0.9576438034683852 0.0131703292413344 59 P30536,P52789,Q8TB36,Q9NS69,Q9Y6C9,O60830,Q9Y512,Q9P0J0,O95831,Q99797,Q10713,O14737,Q15070,Q9Y5J7,O43615,Q9Y5J9,O14925,Q99595,Q5JRX3,Q8N4H5,Q9Y584,Q9Y5L4 22 +Protein targeting 0.4398279546817767 3.4701070608746143 0.0005202509489927 0.9671161977185804 0.0139029076931424 118 P46379,P30536,Q8TB36,Q9NS69,O00560,O60830,Q9Y512,Q9UGP8,Q9P0J0,O95831,Q99797,P43307,O14737,Q10713,Q7Z3B4,O43681,Q9Y5J7,Q14108,O43615,O60725,Q9Y5J9,P55786,O14925,Q99595,Q5JRX3,Q99523,Q13438,Q16543,Q8N4H5,Q96RL7,P46934,Q9Y5M8,P13473,P57105,Q9NQG6,Q15629,Q9Y584,Q9Y5L4 38 +Membrane lipid biosynthetic process 0.7449443820324011 3.4068367985823267 0.0006572041101968 0.9866199583680672 0.0154572522262075 22 Q06136,O15269,O43292,Q9P035,O60762,O15270,Q9NXE4,O60512,P27544,O95470,Q13510,P22059,Q96G23,P04062,Q8NBX0 15 +Cation transport 0.4094397644172127 3.402966895980386 0.0006665835644663 0.9874191549629476 0.0156218619643866 160 Q99623,P30536,P20020,P21796,P24539,Q7KZN9,P16615,Q70HW3,Q13423,P30825,O95202,Q15907,Q9H0U3,Q96NB2,Q9Y6M7,P00403,O75844,Q9HD20,Q4KMQ2,Q96ES6,P33176,P08574,Q9Y619,O75964,Q96GC9,Q15043,P42858,P55011,O43808,Q99959,Q9UDW1,Q06787,P05067,P61586,P13073,Q96PU5,Q9BXP2,Q6P4Q7,Q00325,P12235,O43772,Q8IYU8,O43865,O15173,O76024,P05023,P46934,Q9HD47,O14936,P14854,Q9NUT2 51 +Ceramide metabolic process 0.7889518472786241 3.3513216656500195 0.0008042682196405 0.9949062017168616 0.0174755233684805 18 P17900,O15269,O15270,P06865,O60512,P06280,O95470,Q13510,Q8NCC3,Q96G23,P04062 11 +Lytic vacuole organization 0.7143744283215385 3.347982423798781 0.0008140217377814 0.995222251733732 0.017571087642506 24 P42345,O14773,O75503,P50897,P04062,P10253,Q8N511,P54802,Q14108,Q14457 10 +Glycosylation 0.5257664765837079 3.280817194025655 0.0010350680664057 0.9988813517371868 0.0206447314642993 47 O60512,O60502,Q9H0U3,P04062,Q2TAA5,Q16706,Q8N4A0,P46977,Q86YN1,Q10472,Q96L58,O60476,O60762,Q6ZXV5,O75503,Q9BT22,P04844,O15118,Q8NAT1,O60568 20 +Carbohydrate derivative catabolic process 0.5772375661874455 3.267554243682912 0.0010848107588543 0.9991931656056868 0.0209298537794323 38 P49902,P17900,Q9BTY2,P16278,P15586,Q99519,P06865,Q9H773,P06280,Q13126,O60502,P35610,P54802,P08236,Q9NUJ1,P04062 16 +Vitamin d metabolic process 0.9603267211201836 3.236417069394874 0.0012104039143059 0.9996464484613066 0.0223187534045149 2 P04062 1 +Protein insertion into membrane 0.6360539786251385 3.201973758971659 0.0013648943092883 0.9998718814203764 0.0226619919583567 29 P46379,Q9Y5J9,O14737,Q9NS69,Q96A33,O43681,Q9Y512,Q15070,Q15629,Q9Y5J7,Q9Y584,Q9P0J0,Q9Y5L4,P07900 14 +Pirna metabolic process 0.9524504084013966 3.201590077651417 0.0013667133645707 0.9998734037014132 0.0226619919583567 2 Q9Y2W6 1 +Glycoprotein metabolic process 0.4969016640980644 3.1780589250993767 0.0014826461515307 0.999940903780735 0.0236444962325108 62 Q7LGA3,O14734,O60512,O60502,Q9H0U3,Q2TAA5,Q16706,Q8N4A0,P46977,Q9Y287,Q86YN1,Q10472,Q9UL01,Q96L58,Q9NQX7,Q92542,O60476,O60762,Q6ZXV5,Q9BT22,P04844,O15118,Q8NAT1,P35610,O60568 25 +Manganese ion transport 0.944574095682609 3.1666184538812963 0.0015422252103236 0.999960050467402 0.0243271197839996 2 Q9HD20 1 +Manganese ion transmembrane transport 0.944574095682609 3.1666184538812963 0.0015422252103236 0.999960050467402 0.0243271197839996 2 Q9HD20 1 +Hormone metabolic process 0.6312056912807609 3.1649308871857604 0.0015511979228564 0.9999623381809862 0.0244099778651888 29 O75844,P30536,P42892,P16435,Q9HB40,Q06520,Q6NUM9,O95470,Q14849 9 +Regulation of transmission of nerve impulse 0.9410735122520366 3.151028802856544 0.0016269644507915 0.9999771105627272 0.025419382681177 2 P04062 1 +Regulation of neuronal action potential 0.9410735122520366 3.151028802856544 0.0016269644507915 0.9999771105627272 0.025419382681177 2 P04062 1 +Positive regulation of glycolytic process 0.940490081680276 3.148427722839932 0.0016415131141791 0.9999791979623242 0.0254964926917797 2 P54646 1 +Microglia differentiation 0.9404900816802746 3.148427722839932 0.0016415131141791 0.9999791979623242 0.0254964926917797 2 P04062 1 +Diacylglycerol metabolic process 0.9334889148191324 3.1171520415495895 0.0018260736923245 0.9999938166449708 0.0270746337892113 2 Q8NCC3 1 +Liposaccharide metabolic process 0.7411660763515331 3.065174743482805 0.002175428534697 0.9999993782401412 0.0294287277613261 18 O43292,P17900,P16278,P06865,O60512,P06280,P04062,Q8NBX0 8 +Autophagosome membrane docking 0.921236872812137 3.062139298403647 0.0021976115747963 0.9999994626391454 0.0294287277613261 2 Q96GC9 1 +Calcium ion import into sarcoplasmic reticulum 0.921236872812128 3.0621392984036166 0.0021976115747965 0.9999994626391454 0.0294287277613261 2 O75844 1 +Alcohol metabolic process 0.4275812466180649 3.0597862361984243 0.0022149502032637 0.9999995205487626 0.0294287277613261 87 Q9BQE5,O75874,P48735,P05091,Q06520,Q15392,Q14849,P04062,O15269,Q10713,P37268,Q8WTV0,P54646,P00374,P05067,Q16850,Q6NUM9,Q15800,Q14739,P16435,Q13510,P51648,O15118,Q14534,P35610 25 +Regulation of lysosome organization 0.9168611435239138 3.0424048267202397 0.0023469602144694 0.99999979877733 0.0309629588154354 2 Q14108 1 +Regulation of hormone levels 0.4698111127628068 3.031404465227541 0.0024341893681187 0.9999998866315924 0.0313814354294607 68 O75844,P30536,Q53GQ0,P42892,Q9HB40,P16435,Q06520,P53985,Q15907,P04083,Q6NUM9,O95470,Q14849,Q15043 14 +Lipid catabolic process 0.4236700767204948 3.005457839436662 0.0026518135615285 0.99999997291576 0.033082130400666 87 O75874,O14678,Q9NP80,O14734,Q06520,P06865,P06280,Q16134,P50897,Q8NCG7,O15254,P04062,P23786,Q8N2A8,O14975,Q8WTV0,Q9BWD1,P28288,Q8NHP8,A1L0T0,Q15067,Q2T9J0,P17900,O43808,Q709F0,Q99519,O95470,Q8NCC3,A8MXV4,Q13510,P35610 31 +Organophosphate ester transport 0.6539115180734426 3.003749131672892 0.002666751157303 0.999999975451024 0.0332053531199674 25 Q6NUK1,P08183,P12236,Q4KMQ2,Q9BZF1,P61916,Q8WTV0,Q14108,Q9H2D1,Q8TB61,P12235,P22059,Q9BSK2,Q96GC9 14 +Sphingolipid biosynthetic process 0.7895476801535911 2.992748982141366 0.0027647704545619 0.9999999871194816 0.034230988156293 15 Q06136,O15269,Q9P035,O15270,O60512,O95470,Q13510,Q96G23,P04062 9 +Meiotic cell cycle process 0.4979292518588631 2.9878485845858385 0.0028094870547488 0.9999999904028564 0.0347004219408374 46 P46379,Q14674,O14965,Q13315,O14777,P30153,Q9Y5A9,O43683,Q12768,Q9BZD4,Q96GX5,Q9Y2W6,P42695,O15360,O95067,Q92791,Q9BTX1,O94901,P53350 19 +Alternative mrna splicing via spliceosome 0.4985805410471829 2.987438176286405 0.002813261882433 0.9999999906383152 0.0347004219408374 45 Q00839,P62995,P31483,P52756,P14866,P17844,P23246,Q06787,P51116,O95391,P51114,Q08211,Q96MU7,Q9UHX1,P98175,Q9BWF3,Q07666,P38159 18 +Regulation of systemic arterial blood pressure by endothelin 0.9031505250875064 2.9802708281000916 0.0028799363934122 0.9999999939632962 0.0353897801752265 2 P42892 1 +Regulation of systemic arterial blood pressure by hormone 0.9031505250875064 2.9802708281000916 0.0028799363934122 0.9999999939632962 0.0353897801752265 2 P42892 1 +Response to oxidative stress 0.4156570302756691 2.968757459515673 0.0029900650095622 0.9999999970756656 0.0362007501711205 103 O75874,Q9NP80,Q15165,O43169,P16615,Q8N0U8,O95168,Q16134,P04083,Q15392,Q99720,P04062,Q14457,O95831,O75306,P30519,Q969S3,Q9Y5Z4,P46108,P09601,Q6NUK1,Q15118,P54646,P00374,P05067,O75569 26 +Steroid biosynthetic process 0.4934281608556853 2.966983938555446 0.0030073666880687 0.9999999973904136 0.0363431679688901 49 P30536,Q53GQ0,O14734,Q15392,Q14849,P37268,O14975,Q96SU4,P28288,O75477,P22059,P54646,Q16850,O75845,Q15800,Q14739,P05023,P16435,Q14534,Q13510,O76062 21 +Aminoglycan metabolic process 0.783814300616924 2.9606598874049532 0.0030698073526831 0.9999999982698512 0.0367592624969101 15 Q7LGA3,P16278,P15586,Q9UL01,P06865,P54802,P08236 7 +Detection of other organism 0.8926487747958018 2.932369481882529 0.0033638628172745 0.9999999997503292 0.0393887637235111 2 P04439 1 +Protection from natural killer cell mediated cytotoxicity 0.8926487747958018 2.932369481882529 0.0033638628172745 0.9999999997503292 0.0393887637235111 2 P04439 1 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.8906067677946217 2.9230239506558116 0.0034664985078389 0.9999999998729806 0.0404034870487377 2 O75844 1 +Regulation of vascular associated smooth muscle contraction 0.8879813302217041 2.910993196556734 0.0036028186238488 0.9999999999482392 0.0410049245878907 2 P61586 1 +Positive regulation of bone mineralization 0.8879813302216965 2.9109931965566953 0.0036028186238492 0.9999999999482392 0.0410049245878907 2 Q4KMQ2 1 +Positive regulation of biomineralization 0.8879813302216965 2.9109931965566953 0.0036028186238492 0.9999999999482392 0.0410049245878907 2 Q4KMQ2 1 +Regulation of acyl coa biosynthetic process 0.8868144690781804 2.905640744432333 0.0036650197948373 0.9999999999656368 0.041268283655534 2 Q15118 1 +Hypoxia inducible factor 1alpha signaling pathway 0.8868144690781804 2.905640744432333 0.0036650197948373 0.9999999999656368 0.041268283655534 2 Q15118 1 +Chromosome localization to nuclear envelope involved in homologous chromosome segregation 0.883605600933489 2.890904176887967 0.003841352265157 0.9999999999892432 0.0422227027872058 2 O94901 1 +Microglial cell activation 0.8836056009334856 2.8909041768879487 0.0038413522651572 0.9999999999892432 0.0422227027872058 2 P05067 1 +Ornithine transport 0.882438739789954 2.8855391168084776 0.003907439008048 0.99999999999304 0.0427343579513518 2 Q9Y619 1 +Establishment of protein localization to organelle 0.3604189713562274 2.8787158084869504 0.0039929797853985 0.9999999999960384 0.0431314108156995 186 Q99623,P30536,P46379,P52789,Q8TB36,Q9NS69,P11279,O60830,Q9Y512,Q5SRE5,Q9UGP8,P35658,Q9P0J0,O95831,Q99797,Q10713,O14737,Q7Z3B4,Q99567,O43681,Q15070,Q9Y5J7,Q14108,O43615,Q9Y5J9,O60684,P55786,O15397,O14925,Q99595,Q92973,Q5JRX3,Q99523,Q8N1F7,Q9Y2T2,Q8N4H5,Q96RL7,P46934,Q9HD47,Q9Y5M8,P13473,Q15629,P52294,Q9Y584,Q9Y5L4 45 +Nadh dehydrogenase complex assembly 0.6013914394752754 2.8481289075383844 0.0043977107558879 0.9999999999997248 0.0454425586827282 28 O75306,P51970,Q9Y6M9,O96000,Q86Y39,P03886,O75438,Q96CU9,Q9H061,O95168,O43676,Q15070,Q7L592,Q9P0J0 14 +Cellular lipid catabolic process 0.4327643035589413 2.8390709681950823 0.0045245092918373 0.9999999999998808 0.0465357836567972 75 O75874,O14678,Q9NP80,O14734,P06865,P06280,Q16134,Q8NCG7,P50897,O15254,P04062,P23786,O14975,Q8WTV0,Q9BWD1,P28288,Q8NHP8,A1L0T0,Q15067,Q2T9J0,P17900,O43808,Q709F0,Q99519,O95470,Q8NCC3,A8MXV4,Q13510,P35610 29 +Cellular hormone metabolic process 0.6830926579862293 2.8305860800309017 0.0046462806740652 0.9999999999999466 0.0474166310780967 19 P30536,P42892,Q9HB40,Q6NUM9,O95470,Q14849 6 +Calmodulin dependent kinase signaling pathway 0.869311551925308 2.8249493987110847 0.0047288083306249 0.999999999999969 0.0481092097140479 2 O75844 1 +Membrane lipid catabolic process 0.7944844047760712 2.8158596768231003 0.0048646909340033 0.9999999999999872 0.0490354868032716 13 P17900,P06865,P06280,P50897,O95470,Q13510,P04062 7 +Cytochrome complex assembly 0.8122517169597218 2.807148575659858 0.0049982182724315 0.9999999999999948 0.0500737531354131 12 P53701,Q69YU5,Q6DKK2,Q9Y2R0,Q9BSK2 5 +Establishment of protein localization to membrane 0.409137030034522 2.8065528372875064 0.0050074699500846 0.9999999999999952 0.0500811099257475 89 P46379,Q9NS69,O00560,Q9Y512,Q15907,Q9UGP8,Q9P0J0,Q9HD20,P43307,O14737,Q13277,O43681,Q15070,O60725,Q9Y5J9,Q15904,O15118,Q9NQG6,Q4J6C6,Q15629,Q9Y584,Q96A33,Q9Y5L4 23 +Glyoxylate metabolic process 0.9576559243094688 2.8061190320718112 0.005014216583544 0.9999999999999952 0.0500811099257475 3 O75874 1 +Glycosphingolipid metabolic process 0.8469376794432432 2.793943428523031 0.0052069586731331 0.9999999999999988 0.0513766695942806 10 P17900,P16278,P06865,O60512,P06280,P04062 6 +Modified amino acid transport 0.8626021003500451 2.793815412313686 0.00520902027737 0.9999999999999988 0.0513766695942806 2 Q9H2D1 1 +Fluid transport 0.8617269544924175 2.789746146033729 0.0052749382653138 0.9999999999999992 0.0515859089373915 2 Q99797 1 +Bone maturation 0.855892648774799 2.7625685522238648 0.0057348517469497 1.0 0.0545977179402695 2 P61586 1 +Dna methylation involved in gamete generation 0.9468923256492564 2.7605916904315797 0.0057696759716265 1.0 0.0547910473600776 3 Q9Y2W6,Q8N2A8 2 +Regulation of autophagy 0.4013991647017978 2.7577522701995685 0.0058200286104324 1.0 0.0551491433500649 103 P30536,Q86UE4,P21796,Q13315,Q9NZ45,P04062,Q14457,O75844,O15269,P07602,O15270,Q9UPT5,Q9Y487,P09601,P42858,P54646,Q9NZJ7,P12235,Q93050,P42345,P10619,P46934,O15118,Q8TBX8,P27544 25 +Regulation of membrane potential 0.4463129147201857 2.74642752359812 0.0060248196113334 1.0 0.0568846996972236 68 O75844,P30536,P46934,Q9HD47,Q06787,P05067,P16615,Q9Y5Z4,Q96PU5,Q9UQB8,Q14168,Q9BSK2,P04062 13 +Tetrapyrrole catabolic process 0.9420934229657028 2.740216241334276 0.0061398773755145 1.0 0.0570570771677144 3 P30519 1 +Nitrogen compound transport 0.3115622855731247 2.73880680438093 0.0061662596687301 1.0 0.0570570771677144 608 Q99623,P30536,P24390,Q9NS69,Q92974,O60830,P50897,Q96FV9,Q9UGP8,Q13190,Q15154,Q32P28,Q9HD20,P43307,Q12768,P07602,L0R6Q1,Q7Z3B4,Q99567,Q9Y619,Q9H2D1,O43681,Q8TB61,Q9Y5J7,Q14108,Q9BSK2,A6NIH7,O43615,Q6NUK1,O60725,P55011,O43808,P55786,O15127,Q99595,Q9C0E2,Q5JRX3,Q99523,Q13438,Q9BTX1,Q9Y2T2,Q8N1F7,Q9HAV4,O43731,O15260,O15173,Q8N4H5,Q9Y282,P46934,Q9HD47,Q8NFH4,Q15629,P52294,Q08211,Q9Y584,Q07820,O95487,Q16836,Q9Y5L4,Q8TD16,Q9P2W9,Q9Y5X2,Q9UBN7,Q9HCU5,P04083,Q9ULX6,Q5SRE5,Q96MU7,P35658,Q9P0J0,P07900,P08183,Q96KP1,O14737,P00367,O95249,P49257,Q15070,Q96GC9,Q9Y5J9,O60684,Q06787,O14925,Q92973,Q16850,Q03519,P12235,Q03518,Q96PC5,P10619,Q16543,Q6P4A7,O95391,Q9Y5M8,P13473,P57105,Q92544,P46379,O14678,O00560,P53985,Q9Y512,Q15907,Q8TCT9,Q99797,Q10713,P51991,P14625,Q9Y277,Q14168,P22059,P49321,Q96KC8,Q969Q5,A0AVF1,O15397,Q96L92,Q9NZJ7,P22626,P41208,Q96RL7,Q9BUN8,Q4J6C6,Q8TB36,Q9UBV2,P67809,P30825,Q96NB2,O95831,P12236,P33176,Q13277,Q9UPT5,P50402,Q07666,Q5T9L3,Q6NUQ1,Q92945,Q9Y3B3,O43772,O43865,Q96D46,Q12769,Q15904,Q5HYI8,Q9NQG6,Q8N5M9 147 +Inorganic anion transport 0.6170341270723618 2.7374957043512635 0.0061908928594045 1.0 0.0570570771677144 25 P30536,P08183,Q4KMQ2,P55011,P21796,P51798,Q9UBX3,P45880,O43681,Q9Y277,Q00325,Q9C0H2,Q9UHG3,Q9Y6M7,Q15043 15 +Regulation of alternative mrna splicing via spliceosome 0.5467476730761807 2.7300185020025807 0.0063330771107394 1.0 0.0582856269294145 33 Q00839,P62995,P31483,P52756,P14866,P17844,P51116,Q06787,P51114,Q96MU7,Q9Y580,Q9UHX1,P98175,Q9BWF3,Q07666,P38159 16 +Axonogenesis involved in innervation 0.8485997666277575 2.728476022559838 0.0063627715680478 1.0 0.058313557303813 2 P42892 1 +Regulation of cellular response to osmotic stress 0.8468494749124875 2.720273831121638 0.0065227875863913 1.0 0.059364537578365 2 O95202 1 +Establishment of protein localization to mitochondrial membrane 0.6659386693167366 2.7190940690629852 0.0065460988503636 1.0 0.059364537578365 19 Q9Y5J9,O14737,Q9NS69,Q15070,Q9Y584,Q9Y5L4,Q9P0J0 7 +Inner mitochondrial membrane organization 0.6415620570130194 2.7190412863817204 0.0065471435477495 1.0 0.059364537578365 22 Q9Y5J9,Q9BUR5,Q16891,Q9NVH1,Q5XKP0,Q9Y512,O95202,Q9Y584,Q9Y5J7,O60313,Q13505,Q9Y5L4,Q6UXV4,Q9P0J0 14 +Response to cisplatin 0.8465577596265899 2.7189060458618397 0.0065498209702432 1.0 0.059364537578365 2 P09601 1 +Positive regulation of triglyceride metabolic process 0.8445157526254262 2.7093255179730624 0.0067420156333863 1.0 0.0606873890072448 2 Q8WTV0 1 +Negative regulation of production of molecular mediator of immune response 0.8442240373395418 2.7079560091659403 0.006769899525238 1.0 0.0608110532742757 2 P09601 1 +Carbohydrate derivative transport 0.7727562079650794 2.698099815145815 0.0069736527537387 1.0 0.0615068674328408 13 Q6NUK1,P12236,P07602,P61916,L0R6Q1,Q8WTV0,Q9NZJ7,Q8TB61,P12235 9 +Endoplasmic reticulum organization 0.4788658932960139 2.6972337479374313 0.0069918172389342 1.0 0.0615843016401163 43 P46379,Q9NPA0,Q9P2W9,O95197,P57088,Q9NQC3,Q96A33,Q15041,Q9NXE4,P49257,Q5J8M3,Q12907,Q8NFQ8,O43681,Q15629,Q8NHH9,Q8N5M9 17 +Negative regulation of glial cell proliferation 0.9300955306185936 2.6890653966515705 0.0071652380523461 1.0 0.0624412909687854 3 P30536 1 +Negative regulation of mrna catabolic process 0.6161039889866174 2.663355839259151 0.0077365553792823 1.0 0.066072010330054 24 Q14011,Q00839,P67809,Q13151,P11940,Q99729,Q06787,P35637,Q14103,Q08211,P98175,O60506,Q92804 13 +Phosphatidylcholine catabolic process 0.9235482929676072 2.661025742285456 0.0077903000915902 1.0 0.0661202663029168 3 Q8WTV0,Q8NCC3 2 +Intracellular mrna localization 0.8316802800466616 2.648862786906174 0.0080763114642326 1.0 0.0679257258604773 2 Q99729 1 +Regeneration 0.5321983593261874 2.6479862800421516 0.0080972811344968 1.0 0.0679257258604773 34 P30536,P00374,O14744,P62841,P52294,P04083,Q99707,P09601,Q7Z4V5,Q96G23 10 +Ceramide catabolic process 0.85128826277031 2.6470605199119066 0.0081194820593422 1.0 0.0679257258604773 8 P17900,P06865,P06280,Q13510,P04062 5 +Transepithelial chloride transport 0.8310968494749125 2.646104524819273 0.008142465227573 1.0 0.0679257258604773 2 P51798 1 +Angiogenesis involved in wound healing 0.8310968494749007 2.6461045248192083 0.0081424652275745 1.0 0.0679257258604773 2 P42785 1 +Negative regulation of sodium ion transmembrane transport 0.920047472661356 2.6459960690826025 0.0081450762965209 1.0 0.0679257258604773 3 P46934 1 +Circulatory system process 0.3976090335902249 2.6293488027982663 0.0085548564441184 1.0 0.0704353425173216 81 P20020,Q9UIQ6,P16615,P53985,P30825,O75844,P08183,Q9HB40,P10253,Q9NZ08,P09601,P42892,P61586,P42785,Q96PU5,Q16625,P42345,Q9HD47,O60568 19 +Magnesium ion transport 0.8255542590431739 2.6198577414877855 0.0087966454092429 1.0 0.0718262527508983 2 Q9H0U3 1 +Protein processing involved in protein targeting to mitochondrion 0.913068497670938 2.615957317497278 0.0088977679425947 1.0 0.0720979095527456 3 Q99797 1 +Membrane protein intracellular domain proteolysis 0.8223453908984759 2.6046263870889335 0.0091974492016406 1.0 0.0736020264160562 2 Q8TCT9 1 +Regulation of hormone biosynthetic process 0.8211785297549468 2.5990811873350896 0.0093473662901135 1.0 0.0741685823406593 2 P16435 1 +Regulation of steroid hormone biosynthetic process 0.8211785297549468 2.5990811873350896 0.0093473662901135 1.0 0.0741685823406593 2 P16435 1 +Glycoprotein catabolic process 0.8179696616102534 2.5838139284776793 0.0097714495501692 1.0 0.0769750923748029 2 O60502 1 +Regulation of lipid metabolic process 0.4523909177802054 2.573984598684696 0.0100534748323937 1.0 0.0787866894837352 54 Q99623,P30536,O75874,Q15120,P61916,Q8NCG7,P04083,O75844,P07602,Q8WTV0,O75477,Q96N66,Q2T9J0,Q15118,Q9NZJ7,P42345,P05023,P16435,Q8TBX8,Q8NF37,Q13510,Q96G23 22 +Negative regulation of rna catabolic process 0.53349763475942 2.573137407007102 0.0100781186895944 1.0 0.0787866894837352 32 Q14011,Q9H2U1,Q00839,P67809,Q13151,P11940,Q99729,Q06787,P35637,Q14103,Q08211,P98175,O60506,Q92804 14 +Meiotic cell cycle 0.4399511589556887 2.5728887436184644 0.0100853622340189 1.0 0.0787866894837352 65 P46379,Q14674,O14965,Q13315,O14777,P30153,Q9Y5A9,Q8N2A8,Q12768,O43683,Q9BZD4,Q96GX5,P52701,Q9H2V7,Q9UH99,Q9Y2W6,Q9UQ84,P42695,O15360,Q9H6S0,O95067,Q92791,Q9BTX1,O94901,P53350 25 +Antigen processing and presentation of endogenous peptide antigen 0.8184278791067142 2.567119000989019 0.0102547413044709 1.0 0.0795409130495722 9 P10321,P01889,P04439,Q03519,Q9NZ08,Q03518 6 +Antigen processing and presentation of endogenous antigen 0.8184278791067142 2.567119000989019 0.0102547413044709 1.0 0.0795409130495722 9 P10321,P01889,P04439,Q03519,Q9NZ08,Q03518 6 +Fatty acid elongation 0.8141773628938079 2.565736817150841 0.0102956913533771 1.0 0.0797642581592218 2 Q9P035 1 +Regulation of mitochondrion organization 0.4570821022571464 2.562559204110934 0.010390387097648 1.0 0.0803082687099723 47 Q96A26,P30536,P42858,Q9UG56,Q8N2A8,O14737,P21796,Q9NQG6,Q9Y6C9,P27544,Q9NUQ9,P12235,O60313 13 +Regulation of rna splicing 0.3902088717015531 2.5385652161008516 0.0111308055384395 1.0 0.083570189866408 91 P61978,P52756,P98175,Q9BWF3,P98179,Q13595,Q15427,Q07666,P52597,P55795,P31483,P31943,Q06787,P51114,P22626,P31942,P38159,Q5BKZ1,P51116,P35637,Q9UHX1 21 +Regulation of blood pressure 0.6381099444900199 2.5353012298311106 0.0112350668627245 1.0 0.0841603981200898 19 P20020,P42892,Q9UIQ6,Q9HB40,P61586,P42785,Q9NZ08,P09601 8 +Sodium ion transport 0.5889614161202533 2.5296281434086674 0.0114183470029742 1.0 0.0846997984538021 25 Q4KMQ2,P55011,P05023,P46934,Q9HD47,Q99959,Q96PU5,Q6P4Q7,O43865,Q9Y6M7 10 +Detection of external biotic stimulus 0.8929092500729456 2.5286126726804694 0.0114514323804151 1.0 0.0846997984538021 3 Q8WTV0,P04439 2 +Sodium ion transmembrane transport 0.6212496256038829 2.5221667749213483 0.011663439642618 1.0 0.0852288317760131 21 Q4KMQ2,P55011,Q6P4Q7,P05023,P46934,Q9HD47,Q14BN4,Q96PU5,O43707,Q9Y6M7 10 +Protein localization to organelle 0.2995084012817007 2.514110760028727 0.0119332949581698 1.0 0.0863354812739918 344 Q99623,P30536,P52789,P24390,Q9NS69,O14786,O14965,O14777,O60830,Q9UGP8,Q9NVN8,Q15154,Q7Z3B4,Q99567,Q96DY7,O43681,Q9Y5J7,Q14108,O43615,P55786,Q99595,Q9UK61,Q8NFQ8,Q5JRX3,Q99523,Q13438,Q8N1F7,Q9Y2T2,O43731,Q00839,Q8N4H5,P46934,Q9HD47,Q15629,P52294,Q08211,Q9Y584,Q9Y5L4,Q8TD16,P11279,Q9Y6C9,Q5SRE5,P35658,Q9P0J0,P07900,O14773,O14737,P49257,Q15070,Q9NPI6,Q9Y5J9,O43292,Q9NPA0,O60684,O14925,Q92973,Q9Y6X3,Q9Y5M8,P13473,P46379,Q9Y512,Q99797,Q10713,P31483,A0AVF1,O15397,Q13535,Q96RL7,Q9NQC3,O94901,Q96JB5,Q96HY6,Q96A33,Q8TB36,P67809,Q8IZ07,O95831,Q9P2S5,Q9UPT5,Q9UH99,Q9BZF1,Q96D46,Q76FK4,P53350,Q9Y5V3 85 +T cell tolerance induction 0.8030921820303376 2.512684599159918 0.0119816401395596 1.0 0.0864945243077999 2 P01889 1 +Lymphocyte anergy 0.8030921820303376 2.512684599159918 0.0119816401395596 1.0 0.0864945243077999 2 P01889 1 +Regulation of vasoconstriction 0.888240443536622 2.5082616921870327 0.0121326775725694 1.0 0.0868207527057802 3 P61586,P42892 2 +Xenobiotic transport 0.8019253208867982 2.5070818070348344 0.0121732534012366 1.0 0.0870162187569879 2 P08183 1 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.885030639042895 2.494243671551907 0.0126225858394297 1.0 0.0890638798691808 3 P01889,P04439 2 +Negative regulation of amyloid precursor protein biosynthetic process 0.8849251219146615 2.493782482056773 0.0126389970896858 1.0 0.0890838871133389 3 Q9Y287 1 +Positive regulation of necrotic cell death 0.8713929348257907 2.488332920499028 0.0128343526509375 1.0 0.0902568517334441 7 P30536,P00403 2 +Rna stabilization 0.5648649504305038 2.485184804789646 0.0129484195754081 1.0 0.0906803940809267 27 Q14011,Q9H2U1,Q00839,P67809,Q13151,P11940,P35637,Q14103,Q08211,P98175,O60506,Q92804 12 +Alpha ketoglutarate transport 0.7937572928821297 2.4677643145750605 0.0135959804593646 1.0 0.0928052744034638 2 Q9BQT8 1 +Oligosaccharide catabolic process 0.8779159881534138 2.4630945546758434 0.0137743584869711 1.0 0.0936656377114039 3 P17900 1 +Cytoplasm organization 0.8765684271957884 2.457182652429463 0.0140031469783232 1.0 0.0949262918096666 3 Q9Y2W6,Q8N2A8 2 +Regulation of atp metabolic process 0.5517586088144729 2.4563154447909934 0.0140369881886437 1.0 0.0950574989616927 28 P14406,P30536,P54646,P05067,P00403,Q9BSK2 6 +Chemical homeostasis 0.338422753335782 2.4556865651946227 0.01406157421088 1.0 0.0950645207941632 187 P30536,P20020,P52789,Q15120,P61916,Q9NP80,P16615,P53985,Q9Y6C9,O95202,P50897,Q15907,Q8N511,Q9Y6M7,O15254,P04062,Q9HD20,Q9P035,Q5BJF2,Q8WTV0,P30519,P14625,Q9Y487,Q8NE01,P09601,P22059,Q15043,Q15067,P42858,P55011,P62995,P54646,P05067,P42785,Q96PU5,Q9BXP2,Q6P4Q7,Q8IYU8,Q93050,O15260,O76024,P05023,Q9NQC3,Q9HD47,Q16891,Q15904,O75503,Q8NF37,O15118,Q92544,Q96A33,P35610,Q8N5M9 53 +Icosanoid transport 0.8732538436218211 2.4426248585262944 0.0145808849348092 1.0 0.0974335712242548 3 P04083 1 +Arachidonic acid secretion 0.8732538436218211 2.4426248585262944 0.0145808849348092 1.0 0.0974335712242548 3 P04083 1 +Protein import 0.3843302535439636 2.4418358580884476 0.0146127889251299 1.0 0.0975474271889143 85 Q99623,Q9NS69,O60830,Q9Y512,Q5SRE5,P35658,O95831,O14737,Q7Z3B4,Q99567,O43615,O60684,O15397,O14925,Q99595,Q92973,Q8N1F7,Q9HD47,P13473,P52294 20 +Growth plate cartilage development 0.8718227033676791 2.436332046987206 0.0148370578050847 1.0 0.0985071817494884 3 O75844 1 +Bone growth 0.8718227033676791 2.436332046987206 0.0148370578050847 1.0 0.0985071817494884 3 O75844 1 +Glycolipid catabolic process 0.8068024298028155 2.4317439175149156 0.0150263269813488 1.0 0.0995950886417828 8 P06865,P17900,P06280,P04062 4 +Antigen processing and presentation 0.5753099169156548 2.426895727324999 0.0152286320513399 1.0 0.1006347266071427 25 Q9UIQ6,P10321,P01889,P04439,Q03519,Q9NZ08,Q03518,P04062 8 +Regulation of lipophagy 0.8695652173912978 2.4263969381018993 0.0152495809503949 1.0 0.1006717808817825 3 O15269,O15270 2 +Regulation of phospholipid catabolic process 0.8682526099546354 2.420615248969565 0.0154942669364304 1.0 0.1014980882220987 3 O75874 1 +Regulation of retinal ganglion cell axon guidance 0.7838389731621976 2.4197911342388383 0.0155294240437324 1.0 0.1014980882220987 2 O14786 1 +Neuron projection extension involved in neuron projection guidance 0.7838389731621976 2.4197911342388383 0.0155294240437324 1.0 0.1014980882220987 2 O14786 1 +Roundabout signaling pathway 0.7838389731621865 2.4197911342387863 0.0155294240437346 1.0 0.1014980882220987 2 P61586 1 +T helper 1 cell differentiation 0.867868300174151 2.4189217764760835 0.0155665873062456 1.0 0.1015387136218525 3 P04083 1 +T helper 1 type immune response 0.867868300174151 2.4189217764760835 0.0155665873062456 1.0 0.1015387136218525 3 P04083 1 +Dicarboxylic acid transport 0.6560055421870911 2.417881180841367 0.0156111735138209 1.0 0.1017284216461696 17 O75746,Q02978,P55011,Q9UBX3,Q9H2D1,Q9UJS0,Q9BQT8 7 +Humoral immune response mediated by circulating immunoglobulin 0.7832555425904211 2.416961309866845 0.0156506805779454 1.0 0.101884688444919 2 Q9UQ84 1 +Amino acid transport 0.620365053363366 2.4161983705920895 0.0156835143671323 1.0 0.1019972460625593 19 O75746,Q9H9B4,P55011,Q6P4A7,Q9Y619,Q15041,Q9UJS0,P30825,Q15758,Q96NB2 10 +Triglyceride catabolic process 0.7826721120186735 2.4141306110093455 0.0157728071550744 1.0 0.1024763965857411 2 Q8NCG7 1 +Middle ear morphogenesis 0.8665941085266256 2.413304779259648 0.0158085941045982 1.0 0.1026073140597167 3 P54802 1 +Vitamin transmembrane transport 0.9515469935785112 2.4106965992500147 0.0159220874600787 1.0 0.1029366875990508 4 P38435,P04062,Q9H2D1 3 +Ceramide biosynthetic process 0.7708200518582652 2.4085987287078607 0.0160138942884668 1.0 0.1033444950929329 10 O15269,O15270,O60512,P27544,Q13510,Q96G23,P04062 7 +Bicarbonate transport 0.7800466744457446 2.40138164607801 0.0163332917254903 1.0 0.1048705064861747 2 Q9Y6M7 1 +Diol metabolic process 0.8521540597980927 2.400489807835498 0.0163731467067005 1.0 0.1048705064861747 7 O15269,Q13510,P00374,P04062 4 +Diol biosynthetic process 0.8521540597980927 2.400489807835498 0.0163731467067005 1.0 0.1048705064861747 7 O15269,Q13510,P00374,P04062 4 +Positive regulation of protein neddylation 0.8636501374980918 2.4003137979678075 0.016381022424311 1.0 0.1048705064861747 3 Q92564 1 +Mitochondrion endoplasmic reticulum membrane tethering 0.8619784067697615 2.392928730516939 0.0167144874581259 1.0 0.106313901404283 3 Q96GC9,P16615 2 +Chromosome organization involved in meiotic cell cycle 0.6346675676212599 2.3928100584047094 0.0167198942775403 1.0 0.106313901404283 18 P46379,O94901,Q13315,P42695,Q92791,Q9BTX1 6 +Lipoprotein metabolic process 0.6021573481921342 2.389055920258276 0.0168917310714262 1.0 0.1073025549764755 21 Q9BQE5,O43292,O60762,Q5HYI8,Q13315,P50897,Q9NUJ1,P04062 8 +Aerobic respiration 0.3803435150594338 2.3873214122054316 0.0169716462491191 1.0 0.107705940702824 88 P14406,O75874,Q9Y6M9,P51970,P03886,P48735,Q9UDW1,P24539,P08574,P61586,O75964,Q13423,Q9BSK2,P13073,O43676,Q15070,O14949,P00403 18 +Phosphatidylethanolamine metabolic process 0.8605194047271596 2.3864785922666494 0.0170105977114529 1.0 0.1078488330266225 3 Q9NP80,Q8NCC3 2 +Iron ion transmembrane transport 0.7762543757292699 2.382935227507836 0.0171752160389533 1.0 0.1084733086117561 2 Q15043 1 +Heme transport 0.7762543757292675 2.3829352275078266 0.0171752160389537 1.0 0.1084733086117561 2 O15173 1 +Iron coordination entity transport 0.7762543757292675 2.3829352275078266 0.0171752160389537 1.0 0.1084733086117561 2 O15173 1 +Epithelial cell differentiation involved in prostate gland development 0.8596000343918011 2.3824118160422763 0.0171996508803735 1.0 0.1085231818048185 3 P07602 1 +Mammalian oogenesis stage 0.7745040840140034 2.374409046956411 0.0175770660700274 1.0 0.1094464937456088 2 Q96MU7 1 +Hypothalamus cell differentiation 0.7739206534422454 2.371565240327105 0.0177129192864722 1.0 0.1094464937456088 2 O14786 1 +Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity 0.7739206534422434 2.3715652403270955 0.0177129192864726 1.0 0.1094464937456088 2 P42858 1 +Regulation of organelle transport along microtubule 0.7739206534422414 2.371565240327086 0.0177129192864731 1.0 0.1094464937456088 2 P11279 1 +Positive regulation of synaptic transmission gabaergic 0.7739206534422411 2.371565240327086 0.0177129192864731 1.0 0.1094464937456088 2 P33176 1 +Prostate gland growth 0.8561402849080071 2.3670918404024097 0.0179284832405621 1.0 0.1104663915723652 3 P07602 1 +C21 steroid hormone biosynthetic process 0.8548976639683769 2.3615832753202213 0.0181970844682095 1.0 0.1113349093743824 3 P30536 1 +Nucleotide transport 0.7604782636299847 2.3549786285182255 0.0185237710203953 1.0 0.1113349093743824 10 Q6NUK1,P12236,Q9H2D1,Q8TB61,P12235,Q9BSK2 6 +Cellular response to chemical stress 0.3780451967473794 2.349522093315762 0.0187975285208705 1.0 0.1120083778603035 84 P30536,Q9NP80,Q92974,P16615,Q13315,Q8N0U8,Q9UBN7,O95202,P04083,Q99720,P04062,Q14457,O95831,P11166,Q969S3,P09601,Q6NUK1,P23246,Q15118,P54646,P00374,O75569,Q07820 23 +Response to oxygen levels 0.4095046332276135 2.349281950099933 0.018809657519986 1.0 0.1120083778603035 70 Q99623,Q15120,Q13315,Q8N511,Q14457,O95831,O75306,P14625,P30519,Q9Y487,Q9Y4P3,P09601,Q15118,P61586,Q96A26,P42345,Q15904,Q9NQG6,Q92544 19 +Sphingoid metabolic process 0.9138686131386846 2.3489839802063757 0.0188247167075328 1.0 0.1120083778603035 5 Q06136,O15269,Q13510,P04062 4 +Branchiomotor neuron axon guidance 0.7692532088681501 2.3487833701563714 0.0188348613361908 1.0 0.1120083778603035 2 O14786 1 +Sulfur compound transport 0.8896504313213636 2.344142127468529 0.0190709025455781 1.0 0.1130472109341319 6 Q70HW3,Q9UBX3 2 +Glycerolipid biosynthetic process 0.4351626487603096 2.340873269907884 0.0192386962573927 1.0 0.1137336259828928 50 Q13315,Q14457,Q10713,Q8WTV0,O15228,Q96N66,Q6IAN0,O43292,Q9BTU6,Q8NCC3,Q9NPH0,Q9UG56,P52429,O60762,P48651,Q9NUQ2,Q8TBX8,Q8NF37,Q9H490 19 +Autophagy of mitochondrion 0.5021847571720428 2.3376648613914854 0.0194046403580583 1.0 0.1145083183719233 33 Q99623,P30536,P42858,Q16543,P21796,P27544,P12235,P04062,Q14457 9 +Glycolipid transport 0.8491391887948461 2.336013327416456 0.0194905469438864 1.0 0.1148087693409179 3 Q9NZJ7,P07602 2 +Sterol import 0.7657526254375531 2.331660346230457 0.0197185664519974 1.0 0.1160477426529212 2 Q8WTV0 1 +Regulation of response to osmotic stress 0.847096585935218 2.3269265634962233 0.0199691741284662 1.0 0.117207263533985 3 P08183,O95202 2 +Cell adhesion molecule production 0.763127187864644 2.3187975045046474 0.0204060185804075 1.0 0.1191319340966499 2 Q9H4A6 1 +Inorganic anion transmembrane transport 0.7687070817192584 2.3176585739778255 0.02046788411479 1.0 0.1193868938322243 9 Q4KMQ2,P55011,P51798,Q9UBX3,Q9BXP2,Q00325,Q9UHG3 7 +Regulation of triglyceride metabolic process 0.8447621826670411 2.3165309394890023 0.020529297153399 1.0 0.1195326068505806 3 Q8WTV0,Q96N66 2 +Connective tissue development 0.5512189533176263 2.3078730605268074 0.0210061978211697 1.0 0.1216616682281693 26 O75844,O15173,P43490,P16435,O15270,Q92896,Q8N5W9,Q96HY6,P35610,Q15043 10 +Oligosaccharide metabolic process 0.8802757179623668 2.303461329936765 0.0212529004934343 1.0 0.1228307121086491 6 P10253,P17900,P06280 3 +Reactive oxygen species metabolic process 0.4335077308556324 2.293407766828337 0.02182453990091 1.0 0.12433601949498 44 P30536,Q15067,P00374,P61586,P42785,Q13423,Q9BSK2,P00403,Q9P0J0,Q14457 10 +Negative regulation of cellular amine metabolic process 0.7578763127187845 2.293019000517106 0.0218469110755428 1.0 0.12433601949498 2 O14874 1 +Regulation of necrotic cell death 0.7165006094060505 2.2918144891774572 0.0219163502287009 1.0 0.1244828058582584 12 P12235,P30536,Q9Y5Z4,P00403 4 +Intrinsic apoptotic signaling pathway in response to osmotic stress 0.7575845974329116 2.291584799042199 0.0219296134672561 1.0 0.1244828058582584 2 Q92974 1 +Luteolysis 0.7575845974329054 2.2915847990421683 0.0219296134672579 1.0 0.1244828058582584 2 O94813 1 +Phosphatidylinositol acyl chain remodeling 0.7567094515752422 2.2872808934951694 0.0221794329775835 1.0 0.1254667579300888 2 Q96N66 1 +Positive regulation of mitochondrial translation 0.7763495156414966 2.281412616569335 0.0225240421640218 1.0 0.1267605185937488 8 Q9Y2R0,Q567V2 2 +Glycoside catabolic process 0.8751267023891414 2.281043646572487 0.0225458642616365 1.0 0.1267746026434094 6 Q9BTY2,P06280,Q9NUJ1,P04062 4 +Mitochondrial fusion 0.6815736222388642 2.2744134397752407 0.0229411401347248 1.0 0.1282097473451563 14 Q8N2A8,Q8TB36,Q8NAN2,Q9NQG6,Q9Y6C9,Q9NX63,O60313 7 +Response to steroid hormone 0.3875573956938539 2.272520517527641 0.0230550901961725 1.0 0.1282097473451563 76 P20020,O75874,P30536,O15173,P16435,P46934,P16278,P61586,O15118,Q9H7B4,P04083,Q96HY6,P04062 13 +Negative regulation of mrna metabolic process 0.4305451922659501 2.271223014245213 0.0231334809060437 1.0 0.1285367499622852 47 Q14011,P61978,Q92804,Q00839,P67809,Q13151,P11940,Q99729,Q06787,P35637,P07910,P26368,Q14103,Q08211,P22626,P98175,O60506,P38159 18 +Positive regulation of translation 0.4210769248017105 2.270346756736221 0.0231865522324483 1.0 0.1287226359977379 60 Q14011,P67809,P11940,Q9Y2R0,Q14103,Q567V2,P98179,Q9NWS8,Q07666,O60506,Q9H2U1,Q06787,P61586,P08670,P51114,P42345,Q00839,P51116,Q08211 19 +Regulation of phospholipase a2 activity 0.9159362625202868 2.265735976992698 0.0234675533821175 1.0 0.1300625720383915 4 P50897 1 +Vitamin transport 0.8702097632536103 2.259587562671366 0.0238468602243262 1.0 0.1316089964609157 6 P38435,Q8WTV0,P04062,Q9H2D1 4 +Sphingosine biosynthetic process 0.913601868067716 2.256155575594944 0.0240608896143539 1.0 0.1324560047394215 4 Q13510,O15269,P04062 3 +Respiratory chain complex iii assembly 0.8692509028891383 2.255397830461188 0.0241083688073155 1.0 0.1326061325344551 6 Q69YU5,Q9BSK2 2 +Ceramide transport 0.8913115307444462 2.25394269505297 0.0241997732651513 1.0 0.1329974138743073 5 P08183,P22059,P07602 3 +Keratan sulfate metabolic process 0.8298806855956639 2.2499914416555336 0.0244494885930675 1.0 0.1341451038024322 3 P16278 1 +Tripartite regional subdivision 0.8281295593813662 2.242131182578165 0.0249528951950335 1.0 0.1362663939986489 3 Q9Y2W6,Q8N2A8 2 +Mitochondrial calcium ion transmembrane transport 0.7674601535523952 2.237082108767195 0.0252809740697055 1.0 0.1369714063164965 8 P21796,Q8IYU8 2 +Amide transport 0.4482123540133855 2.2369761981345486 0.02528789572249 1.0 0.1369714063164965 41 P08183,P07602,P53985,Q9H2D1,Q03519,P04083,Q15907,Q03518,P22059 9 +Phosphate ion transport 0.8265692898635735 2.235122234781546 0.0254093250164264 1.0 0.1369714063164965 3 Q9UBX3 1 +Phosphate ion transmembrane transport 0.8265692898635735 2.235122234781546 0.0254093250164264 1.0 0.1369714063164965 3 Q9UBX3 1 +Negative regulation of lipase activity 0.8263787569302449 2.2342659869297297 0.0254655769134601 1.0 0.1369714063164965 3 P04083,P16435 2 +Cellular response to oxygen levels 0.4471983165894871 2.226482189265555 0.0259819006805457 1.0 0.1390519145770286 41 Q99623,O75306,Q96A26,P42345,Q15120,Q15118,Q15904,Q9Y487,Q9NQG6,Q9Y4P3,Q8N511,P09601,O95831 13 +Process utilizing autophagic mechanism 0.3367726787693124 2.2245901727423845 0.0261087629585954 1.0 0.1393104270693489 173 Q99623,P30536,Q86UE4,P21796,P16615,Q13315,Q9NZ45,P04062,Q14457,O75844,O15269,P07602,O15270,Q9UPT5,Q9Y487,P09601,Q96GC9,P42858,Q969Q5,P54646,Q9NZJ7,P12235,Q93050,P42345,P10619,Q16543,Q96RL7,P46934,P13473,O15118,Q8TBX8,P27544,Q96HY6,Q9NNW5 34 +Negative regulation of receptor binding 0.7432905484247179 2.2210440032128553 0.026347981157877 1.0 0.140223400128134 2 P16615 1 +Protein hydroxylation 0.6245619987589893 2.217005139110325 0.0266227403528607 1.0 0.1413042790187394 17 Q32P28,Q96AY3,O75718,P13674,Q92791,O60568 6 +Negative regulation of ire1 mediated unfolded protein response 0.742415402567083 2.2167083696962995 0.0266430264783807 1.0 0.1413042790187394 2 Q96HY6 1 +Regulation of mitochondrial gene expression 0.7182272451600219 2.2138853965494065 0.0268366635651935 1.0 0.1420178921893548 11 Q9Y2R0,Q567V2 2 +Mucopolysaccharide metabolic process 0.7622615845792897 2.2110641466580385 0.0270313953056091 1.0 0.142703150438783 8 P16278,P15586,Q9UL01 3 +Walking behavior 0.8587447078275421 2.209372904345384 0.0271487140778783 1.0 0.1430554704402514 6 O75844 1 +Neutral lipid biosynthetic process 0.9006659917222303 2.2028943725256487 0.0276021943591229 1.0 0.145132691814555 4 Q8NCC3 1 +Oxidative phosphorylation 0.4145667230192059 2.200582895532219 0.0277655655714779 1.0 0.1457738165578725 61 P14406,P51970,Q9Y6M9,P03886,P24539,P08574,Q9UDW1,P61586,O75964,P13073,Q9BSK2,O43676,O14949,P00403 14 +Import across plasma membrane 0.6379984355382643 2.2001374438327197 0.0277971449731855 1.0 0.1458072464540715 16 P55011,P05023,P11166,Q15041,Q9BXP2,P30825,P23634,Q15758,Q15043 9 +Cristae formation 0.7450657813517574 2.1967107153631353 0.0280411131007263 1.0 0.1463848720500923 9 Q9BUR5,Q16891,Q5XKP0,Q9Y512,O95202,Q6UXV4,Q9NVH1 7 +Error free translesion synthesis 0.7377479579930054 2.1935524060064795 0.0282676031700199 1.0 0.1472158825410191 2 Q9Y2S7 1 +Nucleotide excision repair dna gap filling 0.7377479579929995 2.1935524060064515 0.0282676031700219 1.0 0.1472158825410191 2 Q07864 1 +Axon ensheathment in central nervous system 0.7374562427071232 2.1921033393160108 0.0283720456936973 1.0 0.1472279625599424 2 Q92542 1 +Glycine biosynthetic process 0.8160300517455528 2.187646045568395 0.0286953950324337 1.0 0.1480339482726655 3 P00374 1 +Negative regulation of autophagy 0.5518148904629031 2.186970929492938 0.0287446462529388 1.0 0.1481011206920463 24 P30536,P42345,P10619,O15118,Q9Y2S7,P09601,Q14457,Q9NNW5 8 +Glycosylceramide catabolic process 0.815806076126661 2.1866346047096674 0.0287692090455884 1.0 0.1481011206920463 3 P04062 1 +Female gamete generation 0.509757646023652 2.186539959989776 0.0287761244867965 1.0 0.1481011206920463 29 Q8N2A8,Q12768,P62753,Q96GX5,O14965,Q9H6S0,Q13315,Q9Y2W6,O95067,O14777,P53350,Q96MU7,Q9UHI6,P30153 14 +Response to ketone 0.4368116251346167 2.184645414337292 0.0289148553531066 1.0 0.1484657909445117 42 P20020,P30536,P16435,P16278,P54646,Q9H7B4,Q13126,Q14103,P49321,P04062 10 +Regulation of spontaneous synaptic transmission 0.8151200854350449 2.183536127676116 0.0289963514422231 1.0 0.1486516079405219 3 P05067 1 +Spontaneous synaptic transmission 0.8151200854350449 2.183536127676116 0.0289963514422231 1.0 0.1486516079405219 3 P05067 1 +Regulation of lysosomal lumen ph 0.852593623333102 2.1823264520144856 0.0290854481089453 1.0 0.1489919675963303 6 Q8N511,P50897 2 +Nucleotide transmembrane transport 0.7562956327084255 2.181121283189916 0.0291744470344923 1.0 0.1490986927105442 8 P12236,Q9H2D1,Q8TB61,P12235,Q9BSK2 5 +Regulation of cardiac muscle cell action potential involved in regulation of contraction 0.895319910432342 2.1807980472543473 0.0291983570789369 1.0 0.1491047619859798 4 Q9HD47 1 +Maintenance of protein location in mitochondrion 0.8138414429708556 2.177758175141255 0.0294240452502201 1.0 0.150140423741792 3 P30536 1 +Cell migration involved in sprouting angiogenesis 0.7555153263062424 2.1771983199535376 0.0294657736144057 1.0 0.1501444969703605 8 O14786,P09601,P61586,P04083 4 +Tetrapyrrole metabolic process 0.5722833460719268 2.177089847314041 0.0294738644210861 1.0 0.1501444969703605 21 P30536,O14678,P30519,O00264,P22830,Q99707,Q96EY8,P09601 8 +Phospholipid metabolic process 0.3659908436546791 2.1731111218548302 0.0297719548400816 1.0 0.1509764819633816 81 Q99623,O75874,Q9NP80,Q13315,Q14457,O15269,Q10713,P37268,Q8WTV0,O15270,O15228,Q8NHP8,Q96N66,P22059,Q6IAN0,O43292,Q86YN1,Q9BZF1,Q9BTU6,Q9NXE4,Q8NCC3,Q9NPH0,Q9UG56,P52429,O60762,P48651,Q9NUQ2,Q8TBX8,Q8NF37,Q9H490 30 +Behavior 0.3718071578639709 2.1717079615210206 0.0298776976365291 1.0 0.1511888520522806 79 O75844,P30536,P17900,P42345,Q13641,Q7Z2T5,Q96RL7,P42858,P05067,O15118,O00264,P53985,P50897,P54802,P10253,P04062 16 +Action potential 0.541190731665456 2.1654063311465936 0.0303565816350375 1.0 0.1511888520522806 25 P42345,P78310,P05023,Q9HD47,Q99959,Q06787,P16615,Q96PU5,P04062 9 +Aminoglycan catabolic process 0.8703477243121033 2.164770705403128 0.0304052492831685 1.0 0.1511888520522806 5 P16278,P15586,P54802 3 +Glycosaminoglycan catabolic process 0.8703477243121033 2.164770705403128 0.0304052492831685 1.0 0.1511888520522806 5 P16278,P15586,P54802 3 +Intracellular transport 0.2938007823699941 2.1639985721663253 0.0304644589860358 1.0 0.1511888520522806 594 Q99623,P30536,P52789,P24390,Q9NS69,P61916,Q9UBX3,Q92974,P45880,O60830,Q96FV9,Q14849,Q9UGP8,Q9UBK9,O75844,P23786,Q13190,Q15154,P43307,P07602,Q7Z3B4,Q99567,O75964,Q9Y5Z4,P28288,O43681,Q9Y5J7,Q8NHH9,Q14108,O43615,Q96D71,Q86U38,Q6NUK1,O60725,P55786,P23246,Q99595,Q9H223,Q9C0E2,Q5JRX3,Q99523,Q13438,Q8N1F7,Q9Y2T2,Q9HAV4,O43731,O15260,Q00839,Q8N4H5,Q9Y282,P46934,Q9HD47,O75503,Q9Y366,O15118,Q15629,P52294,Q08211,Q9Y584,O95487,Q9Y5L4,Q8TD16,Q9P2W9,P24539,P11279,O43805,Q9Y5X2,Q9UBN7,Q9HCU5,Q96MU7,Q9ULX6,Q5SRE5,Q5SNT2,P35658,Q9P0J0,P07900,O14737,P06576,O95249,P49257,Q9UJS0,Q15070,Q9Y5J9,O60684,O14925,P05067,Q92973,Q03519,P12235,Q03518,Q96PC5,P10619,Q16543,O95391,Q9Y5M8,P13473,P57105,Q92544,P46379,O14678,O00560,P16615,Q9Y512,Q15907,Q14457,Q8TCT9,Q99797,Q10713,P14625,P07437,Q14168,P22059,Q969Q5,A0AVF1,O15397,Q96L92,Q9NZJ7,P22626,Q96RL7,Q9BUN8,Q15057,O94901,Q4J6C6,O60313,Q8TB36,Q9UBV2,Q9BWF3,O95831,P33176,Q13277,Q9UH99,P50402,Q07666,Q5T9L3,P42858,Q6NUQ1,Q8NBN3,Q9Y3B3,O43772,O43865,Q96D46,Q12769,Q15904,Q5HYI8,Q9NQG6,P62841 146 +Mitophagy 0.6471689318368675 2.160515800898863 0.0307327617426145 1.0 0.1511888520522806 15 Q99623,Q16543,P21796,P27544,Q9UBN7,P12235,Q14457 7 +Cellular respiration 0.361664538205503 2.1595635231719688 0.0308064747914749 1.0 0.1511888520522806 105 O75874,P51970,P11177,P48735,P24539,Q7KZN9,O95168,Q13423,Q9NZ45,O43676,Q16134,O14949,P00403,P04062,O75306,P08574,O75964,Q15070,Q9BSK2,P14406,Q9Y6M9,P03886,Q9UDW1,P61586,P13073 25 +Serine family amino acid catabolic process 0.8084721316344935 2.153458505056516 0.0312826618672557 1.0 0.1518319727610443 3 P23378 1 +Metal ion transport 0.3604404648477885 2.15106582050786 0.0314710048283053 1.0 0.1525962083596263 107 P30536,P20020,P21796,P16615,O95202,Q15907,Q9H0U3,Q9Y6M7,O75844,Q9HD20,Q4KMQ2,P33176,Q96GC9,Q15043,P42858,P55011,Q99959,Q06787,P61586,Q96PU5,Q9BXP2,Q6P4Q7,Q8IYU8,O43865,O15173,O76024,P05023,P46934,Q9HD47,O14936,Q9NUT2 31 +Protein catabolic process in the vacuole 0.7489798939940067 2.144281632369548 0.0320103276222278 1.0 0.1540968415074324 8 Q8N511,O14773,P13473,P04062 4 +Lysosomal protein catabolic process 0.7489798939940067 2.144281632369548 0.0320103276222278 1.0 0.1540968415074324 8 Q8N511,O14773,P13473,P04062 4 +Sphingomyelin biosynthetic process 0.8864485025006449 2.144022274422682 0.0320311020749981 1.0 0.1540968415074324 4 O15269,O15270 2 +Cellular potassium ion homeostasis 0.8061272809800282 2.1428279548093556 0.0321269157280457 1.0 0.1544445575146051 3 P55011 1 +Meiotic chromosome segregation 0.5533887207116102 2.1423148114461887 0.0321681577582664 1.0 0.1545296128914672 23 P46379,O43683,Q9BZD4,Q13315,O94901,P53350,Q92791,Q9BTX1 8 +Ganglioside metabolic process 0.8848467216600752 2.13736782914748 0.0325680859025812 1.0 0.1553848233954124 4 P06865,P17900 2 +Ganglioside catabolic process 0.8848467216600752 2.13736782914748 0.0325680859025812 1.0 0.1553848233954124 4 P06865,P17900 2 +Long chain fatty acid transport 0.6430705759779974 2.1354558010344147 0.0327237968310194 1.0 0.1553848233954124 15 P23786,O14678,O14975,Q9NP80,P28288,P04083,O43772 7 +Regulation of metal ion transport 0.4075507346539225 2.1342504727821123 0.0328222830984987 1.0 0.1554527515919106 63 P20020,P30536,Q4KMQ2,P42858,O76024,P05023,P46934,Q9HD47,P33176,P21796,Q99959,Q06787,P61586,O14936,Q96PU5,O43865,Q96GC9 17 +Proton transmembrane transport 0.4444072042848587 2.134123042449311 0.0328327101329248 1.0 0.1554527515919106 40 Q99623,Q96ES6,P05023,P24539,P08574,P06576,Q7KZN9,Q9UDW1,O75964,P05141,P14854,Q13423,P13073,P31930,Q00325,P12235,P56385,P00403 18 +Glycosyl compound catabolic process 0.717768249856536 2.1303434144091367 0.0331432717634838 1.0 0.1562400497930898 10 Q9BTY2,Q13126,P06280,Q9NUJ1,P04062 5 +Plasma membrane phospholipid scrambling 0.8030030110825401 2.1286463898524235 0.0332835273727261 1.0 0.1567885905382833 3 Q4KMQ2 1 +Regulation of macroautophagy 0.4084491708176863 2.1256985761290372 0.0335283655768974 1.0 0.1577091655151165 61 P42858,O15269,P42345,P46934,P21796,O15270,P54646,Q9UPT5,Q9Y487,O15118,Q8TBX8,P04062,P12235,P09601,Q93050,Q14457 16 +Regulation of sodium ion transport 0.5944023612571167 2.1256079378034527 0.0335359181242755 1.0 0.1577091655151165 18 P05023,P46934,Q9HD47,Q99959,Q14BN4,Q96PU5,O43707,O43865 8 +Cellular ion homeostasis 0.362753202627512 2.1249984299023295 0.0335867439091597 1.0 0.1577091655151165 87 P20020,P16615,O95202,P50897,Q8N511,Q9HD20,P14625,Q9Y487,P09601,Q15043,P42858,P05067,Q96PU5,Q8IYU8,Q93050,O76024,Q16891,O75503,Q92544,Q96A33 20 +Regulation of cytoplasmic translation 0.6409199931293827 2.1222814631438207 0.0338141091671591 1.0 0.1583054325012544 15 P42345,Q9H2U1,Q00839,P67809,Q06787,P11940,Q14103,O60506 8 +Protein insertion into mitochondrial inner membrane 0.7923595626698545 2.12217973027577 0.0338226480290702 1.0 0.1583054325012544 7 Q9Y5L4,Q9P0J0,Q9Y584 3 +Prostate gland development 0.8386960599506761 2.1209485128205094 0.0339261354912936 1.0 0.1585636047677129 6 P04083,P07602 2 +Aminoglycan biosynthetic process 0.7439745939285851 2.1189994844641284 0.034090510519013 1.0 0.1591052133895899 8 Q7LGA3,P06865,Q9UL01 3 +L serine transport 0.7222870478413062 2.116459042902354 0.0343057850615231 1.0 0.1597312466059459 2 Q9H9B4 1 +Cellular response to inorganic substance 0.4171353943316824 2.1150073669261276 0.0344293194379567 1.0 0.1598938529766154 45 Q6NUK1,P30536,P55011,P54646,Q06787,P05067,Q9UNS1,Q14168,Q14103,P46108,Q99707,P09601,Q14457,O95831 14 +Cardiolipin acyl chain remodeling 0.7219953325554263 2.1149987484317148 0.0344300539859734 1.0 0.1598938529766154 2 Q6UWP7 1 +Negative regulation of adaptive immune response 0.7217036172695467 2.1135382442101287 0.0345547252432119 1.0 0.1603593402022323 2 Q96FV9 1 +Negative regulation of gliogenesis 0.8361836294126752 2.1098128158951948 0.0348744821317388 1.0 0.1613867078621087 6 P30536 1 +Glial cell proliferation 0.8358213435442349 2.1082060819555313 0.0350131674374945 1.0 0.1619143091788857 6 P30536,P04062 2 +Calcium ion transport 0.4068749813174716 2.1063555732810144 0.0351734773242875 1.0 0.1625032015135916 61 O75844,P20020,P30536,Q4KMQ2,P42858,P21796,Q06787,P61586,P16615,O95202,Q8IYU8,Q96GC9 12 +Lysosomal lumen acidification 0.8562367121034412 2.1042963182541343 0.0353526070277512 1.0 0.1629099770478255 5 Q8N511,P50897 2 +Negative regulation of leukocyte mediated immunity 0.7883977063293485 2.103460682353566 0.035425518745807 1.0 0.1631314063227969 7 P01889,P46108,P04439,P09601 4 +Intracellular protein transport 0.28487801063259 2.1022369391809796 0.0355325254956528 1.0 0.1635094195669525 343 Q99623,P30536,Q9NS69,Q92974,O60830,Q9UGP8,Q13190,Q15154,P43307,Q7Z3B4,Q99567,O43681,Q9Y5J7,Q14108,O43615,O60725,P55786,Q99595,Q9C0E2,Q5JRX3,Q99523,Q13438,Q8N1F7,Q9Y2T2,Q9HAV4,O15260,Q8N4H5,Q9Y282,P46934,Q9HD47,Q15629,P52294,Q9Y584,O95487,Q9Y5L4,Q9P2W9,Q9Y5X2,Q9UBN7,Q9HCU5,Q5SRE5,P35658,Q9P0J0,O14737,Q15070,Q9Y5J9,O60684,O14925,Q92973,P10619,Q16543,O95391,Q9Y5M8,P13473,P57105,Q92544,P46379,O00560,Q9Y512,Q8TCT9,Q99797,Q10713,P14625,Q14168,Q969Q5,O15397,Q96L92,Q96RL7,Q9BUN8,Q8TB36,Q9UBV2,O95831,P33176,Q13277,P50402,Q5T9L3,Q9Y3B3,O43865,Q15904,Q5HYI8,Q9NQG6 80 +Negative regulation of exocytosis 0.7398769018819412 2.098255401725518 0.0358825899284362 1.0 0.1643708352092186 8 P09601,P04083 2 +Fatty acid transport 0.5738255294043413 2.0967626005315014 0.0360145958244086 1.0 0.164494186763449 19 P23786,O14678,O43808,Q9NP80,O14975,P28288,P04083,O43772 8 +Regulation of biomineralization 0.7869634986493336 2.096675941666234 0.0360222716213161 1.0 0.164494186763449 7 O75844,P20020,Q4KMQ2 3 +Respiratory electron transport chain 0.4130539127857622 2.0957851964718186 0.0361012501375992 1.0 0.1645815992699451 51 P51970,Q7KZN9,O95168,O43676,Q16134,O14949,P00403,P04062,O75306,P08574,O75438,P43304,Q9UJS0,P21912,Q9Y6M9,P03886,Q9UDW1,P13073,O96000 19 +Proton transporting v type atpase complex assembly 0.7953087707531308 2.0936363711660575 0.0362923850005478 1.0 0.1645815992699451 3 Q8N511 1 +Vacuolar proton transporting v type atpase complex assembly 0.7953087707531308 2.0936363711660575 0.0362923850005478 1.0 0.1645815992699451 3 Q8N511 1 +T cell selection 0.7947207985882845 2.0909560776352345 0.0365320014474437 1.0 0.1647554344483624 3 P61586 1 +Protein import into mitochondrial matrix 0.7245749311794735 2.0906826163179533 0.0365565243152721 1.0 0.1647554344483624 9 O60830,Q99595 2 +Purine nucleotide transport 0.7380937151183531 2.089215266485224 0.0366883497889309 1.0 0.1651227375274109 8 Q6NUK1,P12236,O43808,Q8TB61,P12235 5 +Regulation of mrna splicing via spliceosome 0.3964693826975082 2.0877312022142305 0.0368220885646828 1.0 0.1652712347205532 67 Q14011,P61978,P52756,P14866,Q96MU7,P98175,Q9BWF3,P98179,Q13595,Q15427,Q07666,P62995,P31483,Q96EP5,Q06787,P26368,P51114,P22626,P38159,Q00839,P51116,Q07021,Q9UHX1 23 +Regulation of membrane depolarization 0.6790995127221179 2.0827228856342903 0.0372764901516782 1.0 0.1668542485506906 12 Q9HD47,P30536 2 +Immature b cell differentiation 0.7147024504083858 2.0784234511894457 0.0376703746147055 1.0 0.168272973602245 2 Q13315 1 +Cholesterol storage 0.7917709155447761 2.077498419198948 0.0377555809903711 1.0 0.1685388588155206 3 Q8WTV0 1 +Organic hydroxy compound metabolic process 0.3504438082578481 2.074838285182629 0.0380015249965091 1.0 0.1687357131863135 119 Q9BQE5,O75874,P38435,P48735,P05091,Q06520,Q15392,Q14849,P21964,P04062,O15269,Q10713,P37268,Q8WTV0,O15270,P54646,P00374,P05067,Q16850,Q6NUM9,Q15800,Q14739,P16435,Q13510,P51648,O15118,Q14534,P35610 28 +Transmission of nerve impulse 0.7816089080907823 2.071306093155242 0.0383302002326368 1.0 0.1697184709356027 7 Q06787,P04062 2 +Regulation of retrograde protein transport er to cytosol 0.7901854938034506 2.0702583491306896 0.0384281577489549 1.0 0.1700374721164141 3 Q13438 1 +Spindle assembly involved in female meiosis 0.7899037058651809 2.068970994556979 0.0385488086310004 1.0 0.1701367436473185 3 O14965,O14777 2 +Nerve development 0.7203598603942268 2.0687364793128418 0.0385708220309204 1.0 0.1701367436473185 9 Q9H061 1 +Regulation of bone mineralization 0.84758330038614 2.0670340180574085 0.0387309486101177 1.0 0.1703434884581719 5 O75844,P20020,Q4KMQ2 3 +Sterol transport 0.5206105074433736 2.0657168689319896 0.0388552215249853 1.0 0.170661287581629 26 P30536,Q9BZF1,P61916,Q8WTV0,O15118,P35610,Q14849,P22059 8 +Regulation of mitochondrial fusion 0.8469581090287539 2.064336728236683 0.0389858009670591 1.0 0.1708916672984918 5 Q9Y6C9 1 +Amino acid transmembrane transport 0.645731696900395 2.0618870640806186 0.0392184893924347 1.0 0.1714535159181592 14 O75746,Q9H9B4,Q9Y619,Q15041,Q9UJS0,P30825,Q15758,Q96NB2 8 +Regulation of membrane depolarization during action potential 0.7872101844823118 2.0566575731781365 0.0397191759688591 1.0 0.1723791221611464 3 Q9HD47 1 +Membrane depolarization during cardiac muscle cell action potential 0.7872101844823118 2.0566575731781365 0.0397191759688591 1.0 0.1723791221611464 3 Q9HD47 1 +Regulation of membrane depolarization during cardiac muscle cell action potential 0.7872101844823118 2.0566575731781365 0.0397191759688591 1.0 0.1723791221611464 3 Q9HD47 1 +Crd mediated mrna stabilization 0.7172065055681826 2.052288395368553 0.0401416431279491 1.0 0.1739824717342153 9 Q00839,P67809,P11940,Q14103,O60506 5 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.7172065055681826 2.052288395368553 0.0401416431279491 1.0 0.1739824717342153 9 Q00839,P67809,P11940,Q14103,O60506 5 +Peptidyl proline hydroxylation 0.7300414537424326 2.048295883020132 0.0405310161540519 1.0 0.1747282480974809 8 O75718,Q32P28,P13674 3 +Nucleobase containing compound transport 0.3544745553229835 2.0458003519408594 0.0407760174060041 1.0 0.1751127134935857 105 Q8TD16,P67809,Q96MU7,Q9ULX6,Q5SRE5,Q96FV9,P12236,P51991,L0R6Q1,Q7Z3B4,Q99567,Q9H2D1,Q8TB61,Q07666,Q9BSK2,Q6NUK1,O43808,Q06787,Q92945,P22626,P12235,P41208,Q9BTX1,Q8N1F7,Q9HAV4,Q12769,Q8NFH4,Q08211 28 +Programmed cell death involved in cell development 0.7071178529755018 2.040247665309326 0.0413256644545478 1.0 0.1767790157436472 2 P78527 1 +Ectopic germ cell programmed cell death 0.7071178529755018 2.040247665309326 0.0413256644545478 1.0 0.1767790157436472 2 P78527 1 +Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c 0.7071178529755016 2.040247665309322 0.0413256644545483 1.0 0.1767790157436472 2 Q9NR28 1 +Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway 0.7071178529754987 2.0402476653093085 0.0413256644545496 1.0 0.1767790157436472 2 P49327 1 +Multicellular organismal signaling 0.5004241403252196 2.034170600223971 0.041934397675996 1.0 0.1780161844290134 28 O75844,P20020,P42345,P78310,Q9HD47,Q99959,Q06787,P16615,P04062 9 +Homologous chromosome segregation 0.6853538655174714 2.0341108751804367 0.0419404177274085 1.0 0.1780161844290134 11 P46379,O94901,Q13315,P53350,Q92791,Q9BTX1 6 +Positive regulation of macroautophagy 0.5317298491197107 2.033437637468661 0.0420083280685921 1.0 0.1780746495451593 24 P42858,O15269,P21796,O15270,P54646,Q8TBX8,P12235,P09601,Q14457 9 +Female meiotic nuclear division 0.6702265035907813 2.0324909784679037 0.0421039761627255 1.0 0.1780746495451593 12 Q12768,Q96GX5,O14965,Q13315,O95067,O14777,P53350 7 +Mitochondrial adp transmembrane transport 0.7817332944266004 2.031575483407109 0.0421966507411282 1.0 0.1780836775828134 3 P12235,P12236 2 +Nucleobase transport 0.7817332944265942 2.0315754834070785 0.0421966507411313 1.0 0.1780836775828134 3 P12235,Q9Y277 2 +Protein transmembrane transport 0.5237533284968955 2.0291916313978344 0.0424387756247857 1.0 0.178744060109014 25 Q9NS69,O14925,Q99595,O60830,Q15629,Q9Y584,O43615,Q9UGP8,O95831 9 +Positive regulation of cytoplasmic translation 0.6843529970629435 2.0285888850578653 0.0425001816093812 1.0 0.1787566148450518 11 Q9H2U1,Q00839,P67809,P11940,Q14103,O60506 6 +Positive regulation of autophagy 0.4641089235758297 2.0281053088503675 0.0425495012121275 1.0 0.1787566148450518 34 P42858,O15269,Q86UE4,P21796,O15270,P54646,Q8TBX8,P12235,P09601,Q14457 10 +Lipoprotein localization 0.7259898190616632 2.027646835577552 0.0425963052739306 1.0 0.1787566148450518 8 O15260,A6NIH7 2 +Negative regulation of programmed necrotic cell death 0.7808306821972446 2.0274361617127035 0.0426178268864185 1.0 0.1787566148450518 3 P12235 1 +Negative regulation of necrotic cell death 0.7808306821972446 2.0274361617127035 0.0426178268864185 1.0 0.1787566148450518 3 P12235 1 +Positive regulation of t cell migration 0.7806833496038095 2.026760351412597 0.0426869270743974 1.0 0.1787566148450518 3 P05067 1 +Positive regulation of lymphocyte migration 0.7806833496038095 2.026760351412597 0.0426869270743974 1.0 0.1787566148450518 3 P05067 1 +Phosphatidylcholine acyl chain remodeling 0.7798195995000208 2.022797495026793 0.0430940300584306 1.0 0.180106689526838 3 Q96N66 1 +Regulation of cell migration involved in sprouting angiogenesis 0.8373002819336498 2.0225819377517875 0.0431162679677705 1.0 0.180106689526838 5 P09601,P61586,P04083 3 +Regulation of lipase activity 0.6684601233660782 2.022463097036707 0.0431285322855186 1.0 0.180106689526838 12 Q99623,P16435,P61586,P04083,P50897 5 +Selective autophagy 0.481703800901001 2.022061551382027 0.0431699934606921 1.0 0.180106689526838 30 Q99623,P42858,O15269,Q16543,Q96HY6,P21796,O15270,P27544,P12235,Q14457 10 +Glycosylceramide metabolic process 0.8570629875000417 2.021253024597248 0.0432535792435273 1.0 0.1801577489906807 4 O60512,P04062 2 +Pronephros development 0.7033255542590446 2.0211077813366956 0.0432686090230589 1.0 0.1801577489906807 2 O15078 1 +Positive regulation of mitochondrion organization 0.5371550228563082 2.020330357282426 0.0433491319464374 1.0 0.1802642609838544 23 Q96A26,P42858,Q8N2A8,O14737,P21796,Q9NQG6,P27544,P12235 8 +Nervous system process 0.3509978864011721 2.0173794688212494 0.043655928170095 1.0 0.1810232079041502 110 Q13641,O00264,Q9UQB8,P50897,Q9H0U3,P04062,O75844,Q99797,O14773,P10253,Q9Y5J7,Q7L576,Q14168,Q14108,Q9Y5J9,P17900,Q9Y6M9,P42858,Q06787,P05067,O75569,Q6P4Q7,P42345,O76024,O60313,Q9Y5L4 26 +Lipid homeostasis 0.5063752708554101 2.0152033040390824 0.0438833514856167 1.0 0.1816798438161621 27 O15260,Q9NP80,Q5BJF2,Q8WTV0,P54646,O15118,Q9Y6C9,P35610,O15254,Q15067 10 +Protein containing complex localization 0.4065439873301579 2.014235541222838 0.0439848098613913 1.0 0.1818703984312852 50 Q15154,Q00839,Q12768,A0AVF1,P23246,P33176,Q99567,Q13277,Q96D46,Q9Y366,P57105,Q13315,Q13535,P62841,Q14168,Q9BTX1,Q86U38 17 +Tangential migration from the subventricular zone to the olfactory bulb 0.7012835472578811 2.010787458785024 0.0443479113688094 1.0 0.1830257826428475 2 O94813 1 +Maintenance of location 0.3737987004237514 2.008127342443608 0.0446297614094766 1.0 0.1839633174743458 74 P30536,P42858,O43292,P17900,O43731,P24390,Q96RL7,Q8WTV0,P14625,Q9UH99,O94901,O95202,P10253,Q14534,P35610,P04062 16 +Magnesium ion homeostasis 0.7765199706685895 2.0076454189210886 0.0446809844915558 1.0 0.1839633174743458 3 Q8NE01 1 +Regulation of sulfur metabolic process 0.7764808870732259 2.0074658171173474 0.0447000868359492 1.0 0.1839633174743458 3 Q15118,Q15120 2 +Mitochondrial cytochrome c oxidase assembly 0.8337803677336745 2.00732326800549 0.0447152531806738 1.0 0.1839633174743458 5 Q9Y2R0 1 +Cell motility involved in cerebral cortex radial glia guided migration 0.700408401400213 2.0063614281832174 0.0448177004879344 1.0 0.184269267294377 2 O94901 1 +Modification of synaptic structure 0.7215444516747436 2.0049455711641015 0.044968866131587 1.0 0.1845439021610219 8 Q9UQB8,P61586,O00264 3 +2 oxoglutarate metabolic process 0.6935554825699797 2.0007590642334443 0.0454183608663989 1.0 0.185469025407427 10 O75874 1 +Homologous chromosome pairing at meiosis 0.7207219464377957 2.000740068439124 0.0454204089956926 1.0 0.185469025407427 8 P46379,Q92791,Q9BTX1 3 +Negative regulation of phosphatidylinositol 3 kinase signaling 0.7745616243829637 1.998642513887986 0.0456470469915903 1.0 0.1860471567446062 3 Q10713 1 +Response to corticosteroid 0.4736002390389952 1.994300799149338 0.0461191919742538 1.0 0.1877382988430854 31 P20020,P16435,P16278,P61586,Q9H7B4,P04083,P04062 7 +Peptidyl glutamic acid modification 0.8301181646405894 1.99142496981876 0.0464341863574679 1.0 0.1889033669421605 5 Q8N0U8 1 +Innervation 0.7722516374709131 1.9880134518232988 0.0468102022630207 1.0 0.1896102143518163 3 P42892 1 +Calcium ion import 0.6472060581097132 1.9871067467421073 0.0469105687556674 1.0 0.1898995386642133 13 O75844,P21796,P16615 3 +Negative regulation of macroautophagy 0.6905162348877653 1.9843825930705452 0.0472132050361453 1.0 0.1906541855059604 10 P42345,P09601,Q14457,O15118 4 +Organic hydroxy compound biosynthetic process 0.4006040095419238 1.9821719127030832 0.047460003117888 1.0 0.1910629082574117 55 P05091,O14734,Q15392,P04062,O15269,P37268,O14975,Q96SU4,O15270,P28288,P22059,P54646,P00374,Q16850,O75845,Q15800,Q14739,Q14534,P16435,Q13510,O76062 21 +Negative regulation of glycoprotein metabolic process 0.8469442475516231 1.978646201829708 0.0478558539702511 1.0 0.192157239608004 4 Q9NQX7,Q9Y287 2 +Localization within membrane 0.3123231263440895 1.977104311667406 0.048029840519159 1.0 0.1925301243046558 191 P46379,Q13641,Q9NS69,O00560,O00264,P35613,Q9Y512,Q15907,Q9P0J0,Q9HD20,P43307,O14737,P07602,P33176,Q13277,Q15070,Q14168,O60725,Q9Y5J9,Q96L92,Q9NZJ7,Q9HD45,Q92544,Q9BTX1,Q9HD47,Q15057,P57105,O15118,Q4J6C6,Q15629,Q9Y584,Q96A33,Q9Y5L4 33 +Peroxisome fission 0.7693194453225889 1.974506520706134 0.0483241767261439 1.0 0.1932030368763239 3 O14734 1 +Chondroitin sulfate biosynthetic process 0.7690558944035137 1.9732916801452929 0.0484623402746642 1.0 0.1932030368763239 3 Q9UL01 1 +Chondroitin sulfate proteoglycan metabolic process 0.7690558944035137 1.9732916801452929 0.0484623402746642 1.0 0.1932030368763239 3 Q9UL01 1 +Chondroitin sulfate proteoglycan biosynthetic process 0.7690558944035137 1.9732916801452929 0.0484623402746642 1.0 0.1932030368763239 3 Q9UL01 1 +Neuronal action potential 0.8255346601313659 1.97149459444928 0.0486673306987524 1.0 0.1935484994213413 5 Q06787,P04062 2 +Hormone biosynthetic process 0.6879778467201305 1.9706863671928767 0.0487597608429171 1.0 0.1937802584155664 10 P30536,P05023,Q53GQ0,P16435,Q14849 5 +Low density lipoprotein particle clearance 0.6879375490910526 1.9704688001746071 0.0487846673121785 1.0 0.1937802584155664 10 Q8WTV0,P61978,P35610,P09601 4 +Alcohol biosynthetic process 0.4447978392379691 1.9689643675981705 0.0489571830194517 1.0 0.1943365578101643 37 O15269,P37268,P16435,O15270,P54646,P00374,Q16850,Q15392,Q15800,Q13510,Q14739,P04062 12 +Maintenance of protein localization in organelle 0.5552897036172219 1.9667470874923216 0.0492123754014013 1.0 0.1950070092898523 19 P30536,O43292,O43731,P52789,P24390,Q9UH99,O94901,Q13438 8 +Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.7664501526875338 1.9612733083748273 0.049847149206702 1.0 0.1969277502073323 3 Q99729 1 +Rhythmic process 0.3908274063626231 1.9603763838926704 0.0499518140601427 1.0 0.1971039109216214 65 P17844,Q9UNS1,Q14103,P04083,O75592,Q9BWF3,P43490,Q03164,P78527,P42574,P23246,Q9H2P0,P54646,O14744,O95470,P54802,P42345,Q00839,O94813,Q08211,Q9Y5V3 21 +Transepithelial transport 0.822189781021894 1.9569274582680796 0.0503559977398999 1.0 0.1972752580114767 5 P08183,O43865,P55011,P51798 4 +Response to mitochondrial depolarisation 0.7116156408063392 1.9540718508997512 0.0506927205248524 1.0 0.1982393516591665 8 Q16543,P52789,P04062,Q14457 4 +C21 steroid hormone metabolic process 0.8400319165107706 1.9494453321023553 0.0512422653460897 1.0 0.200149848333953 4 P30536 1 +Multicellular organism aging 0.6838074493889165 1.948148032553536 0.0513972528822499 1.0 0.2005165121363401 10 O75844,Q13315,P04062 3 +Phosphatidic acid metabolic process 0.6969684208611273 1.9461270938148696 0.0516394747662092 1.0 0.2005183496279722 9 Q9NUQ2,O15228,Q9NPH0,P52429 4 +Monovalent inorganic cation homeostasis 0.4899339593143599 1.9458335787269003 0.0516747336657903 1.0 0.2005183496279722 28 P55011,P05023,Q15904,O75503,Q9Y487,Q96PU5,Q9BXP2,Q93050,P50897,Q92544,Q8N511,Q9Y6M7 12 +Intraciliary transport involved in cilium assembly 0.7630841617367621 1.945729256863053 0.0516872703232618 1.0 0.2005183496279722 3 A0AVF1 1 +Neural precursor cell proliferation 0.4811275789750182 1.9413999549123664 0.0522097837723873 1.0 0.2017269001441783 29 O75306,Q15154,Q9UKA9,P61586,Q92974,P55209,Q8NEM2,Q8NCG7 8 +Lipophagy 0.8182967646390447 1.9399492849616176 0.0523858535998649 1.0 0.2017269001441783 5 O15269,O15270 2 +Regulation of oxidoreductase activity 0.5821693170765294 1.939779496450705 0.0524064934841164 1.0 0.2017269001441783 17 P16435,Q8WTV0,P00374,P06280,Q15070,Q9BQ95 6 +Peripheral nervous system axon regeneration 0.8368062124497988 1.935792385898236 0.0528931338444846 1.0 0.2030923020991857 4 P30536 1 +Female genitalia development 0.6861143523920671 1.9338152263183868 0.0531358500174627 1.0 0.2039049402424508 2 Q07812 1 +Maintenance of protein location in cell 0.5115146238140013 1.9325802124826597 0.053287931973833 1.0 0.2043690295805334 25 P30536,O43292,O43731,P52789,P24390,Q96RL7,Q9UH99,O94901,Q13438 9 +Regulation of action potential 0.623478787999699 1.9277605941501796 0.0538849112575656 1.0 0.2061765525785107 14 Q9HD47,Q99959,Q06787,P16615,P04062 5 +Positive regulation of cell migration involved in sprouting angiogenesis 0.8343067998181362 1.9252021959395276 0.0542040674922383 1.0 0.2071801647092978 4 P09601,P04083 2 +Cerebellar purkinje cell layer development 0.7509969497671541 1.925106718821576 0.0542160085825798 1.0 0.2071801647092978 7 P04062,P54802 2 +Intraciliary retrograde transport 0.6843640606767807 1.9248995462942091 0.0542419266946927 1.0 0.2071801647092978 2 Q9P2L0 1 +Regulation of nervous system process 0.6229073669023506 1.9242952891582612 0.0543175807395952 1.0 0.2072570851247376 14 Q06787,Q9UQB8,P04062 3 +Organelle fusion 0.4238909398492063 1.9220098257824023 0.0546045213976684 1.0 0.2078392513987822 40 Q86Y82,Q13190,Q8N2A8,Q8TB36,Q8NAN2,Q13277,Q07812,O95249,Q9NQG6,Q9Y6C9,Q9UNK0,Q9NX63,P04083,Q8IWA4,Q9Y4W6,O60313,P51809 17 +Axonal fasciculation 0.7578056609279136 1.9213100844181503 0.054692626548582 1.0 0.207933380887483 3 O14786,Q9NQC3 2 +Neuromuscular process 0.4701126146307375 1.9195478612060193 0.0549150352651819 1.0 0.2084640784298924 30 O75844,O14773,P17900,P05067,P10253,P04062 6 +Glycolipid biosynthetic process 0.7043364271022912 1.916627526023164 0.0552852684648517 1.0 0.2094583901075963 8 O60762,O43292,O60512,Q8NBX0 4 +Regulation of ion transport 0.3486162574571135 1.9137213710497645 0.0556557668823674 1.0 0.2107404167813588 91 Q99623,P30536,P20020,P21796,Q15907,O75844,P08183,Q4KMQ2,P33176,Q96GC9,P42858,P55011,Q99959,Q06787,P05067,P61586,Q96PU5,O43865,O76024,P05023,P46934,Q9HD47,O14936 23 +Muscle hypertrophy in response to stress 0.754878884893541 1.9077478497386933 0.0564238139980868 1.0 0.2128981932291062 3 P16615 1 +Dna methylation 0.5468404577979797 1.906976050369617 0.0565236889118068 1.0 0.2128981932291062 19 O75844,Q9Y2W6,Q8N2A8 3 +Amino acid import 0.7024580750826951 1.906945452391636 0.0565276514822699 1.0 0.2128981932291062 8 Q9H9B4,P30825,Q15041,Q96NB2 4 +Cartilage development involved in endochondral bone morphogenesis 0.8299626418666393 1.906772385867162 0.0565500686983133 1.0 0.2128981932291062 4 O75844 1 +Organic cation transport 0.8295829663823481 1.9051602397848504 0.0567592448400362 1.0 0.213295298442075 4 Q70HW3,O43772 2 +Positive regulation of chemokine production 0.7466423088073648 1.9041531647413448 0.0568902393735535 1.0 0.2134441113603535 7 P09601 1 +Nerve growth factor signaling pathway 0.7540122556171565 1.90372896581304 0.056945491973257 1.0 0.2135293247591501 3 Q9Y4G8,Q99523 2 +Regulation of tolerance induction 0.7536428676738617 1.902015553134814 0.0571691213087501 1.0 0.214001011995447 3 P01889 1 +Tolerance induction 0.7536428676738617 1.902015553134814 0.0571691213087501 1.0 0.214001011995447 3 P01889 1 +Cellular response to estradiol stimulus 0.7534230380965741 1.90099574990394 0.0573025693057118 1.0 0.2141340887153082 3 Q14103 1 +Blastoderm segmentation 0.8283712784588225 1.900013777941632 0.0574313115539375 1.0 0.2142084726770722 4 O14786,Q9Y2W6,Q8N2A8 3 +Necrotic cell death 0.545845605403396 1.8999180449556088 0.0574438755634227 1.0 0.2142084726770722 19 P12235,P30536,Q9Y5Z4,P00403 4 +Regulation of protein lipidation 0.8279878418368001 1.8983847154316909 0.0576454215808577 1.0 0.2142084726770722 4 P04062 1 +Fatty acid transmembrane transport 0.7453240836216601 1.8978027114527911 0.0577220759109824 1.0 0.2142084726770722 7 O43772,P23786,P28288,O14678 4 +Negative regulation of sodium ion transport 0.827583798927868 1.896667859643988 0.0578717881850172 1.0 0.2142084726770722 4 P46934 1 +Regulation of morphogenesis of an epithelium 0.7523374255948128 1.895958217218379 0.0579655697544925 1.0 0.2142084726770722 3 Q9Y5V3 1 +Protein retention in er lumen 0.8080509547338126 1.8951443422077192 0.0580732814526838 1.0 0.2142084726770722 5 O43731,P24390 2 +Maintenance of protein localization in endoplasmic reticulum 0.8080509547338126 1.8951443422077192 0.0580732814526838 1.0 0.2142084726770722 5 O43731,P24390 2 +Steroid hormone biosynthetic process 0.6999446301316914 1.8939771801915488 0.0582280388959997 1.0 0.2146586467615449 8 P30536,Q14849 2 +Reactive nitrogen species metabolic process 0.5746542648862029 1.8898993173528265 0.0587714268789052 1.0 0.2161760668045831 17 P30536,P06280,O43169,P16435 4 +Glycerophospholipid biosynthetic process 0.3969214988680978 1.888853808155678 0.0589114204053937 1.0 0.2163272191942887 46 Q9UG56,Q6IAN0,O43292,Q10713,P52429,O60762,P48651,Q9NUQ2,Q9BTU6,Q9H490,Q13315,O15228,Q8TBX8,Q8NF37,Q96N66,Q9NPH0,Q14457 17 +Plasma lipoprotein particle clearance 0.6590273685288894 1.8879427705888356 0.0590336338203962 1.0 0.2165336529510566 11 Q8WTV0,P61978,P35610,P09601 4 +Energy derivation by oxidation of organic compounds 0.3360585678814448 1.887028535919378 0.0591564876141201 1.0 0.2168576246315786 125 O75874,P51970,P48735,P24539,Q13423,Q9NZ45,O43676,O14949,P00403,P04062,P08574,O75964,Q15070,P10253,Q9BSK2,P14406,Q9Y6M9,P03886,Q9UDW1,P61586,P13073,P42345 22 +Meiosis i cell cycle process 0.525837757427347 1.884850375180751 0.0594500415644683 1.0 0.2170902463806572 22 P46379,Q14674,O14965,Q13315,O94901,O95067,O14777,P53350,Q92791,Q9BTX1 10 +Response to dexamethasone 0.685146433295107 1.8836469841220245 0.0596127420487269 1.0 0.2174148335431844 9 Q9H7B4,P04062 2 +Germ cell proliferation 0.6759043173862347 1.8817095554949357 0.0598754616305199 1.0 0.2180370583903839 2 Q13162 1 +Glutamate biosynthetic process 0.7487396018801877 1.8792478765144849 0.0602106551702554 1.0 0.2186509790964119 3 P00367 1 +Determination of adult lifespan 0.7411782254446555 1.877807989653902 0.0604074368891622 1.0 0.2191566003286325 7 O75844,P04062 2 +Semaphorin plexin signaling pathway involved in neuron projection guidance 0.7484152870987397 1.8777404119259384 0.0604166854609107 1.0 0.2191566003286325 3 P42892 1 +Glutamate receptor signaling pathway 0.8228254524226296 1.8764298566511912 0.06059627802053 1.0 0.2195977195346082 4 Q06787,P05067,Q8NCG7 3 +Electron transport chain 0.37752197016695 1.8691625798467528 0.0616001986550869 1.0 0.2205053405382088 68 P51970,P05091,Q7KZN9,O15460,O95168,O43676,Q16134,O14949,P00403,P04062,Q9P0J0,O75306,P08574,O75438,P43304,Q9UJS0,P21912,Q9Y6M9,P03886,Q9UDW1,P13073,P23378,P16435,O96000 24 +Detection of biotic stimulus 0.8020810650935047 1.8689585024360529 0.0616285880138791 1.0 0.2205053405382088 5 P30536,Q8WTV0,P04439 3 +T cell differentiation 0.4883925894257523 1.8665226352470925 0.0619682802274892 1.0 0.2211179199852008 27 P42345,P24390,O15360,O96005,P61586,P04083,P04062 7 +Protein o linked glycosylation 0.5851537988658666 1.8636683537494951 0.0623682921339234 1.0 0.2219418291663806 16 O60762,Q6ZXV5,Q9H9S5,Q10472,Q8N4A0,Q8NAT1,O60502,O43505,O60568 9 +Isotype switching to iga isotypes 0.7451242386044964 1.8624323289510465 0.0625421757528579 1.0 0.2223194784887614 3 O96028 1 +Regulation of skeletal muscle cell differentiation 0.7443828421359797 1.8589810774366196 0.0630298205927331 1.0 0.2236893903350538 3 P17844,Q9BYT8 2 +Chloride transmembrane transport 0.7797248193873306 1.8564828863888967 0.0633847601076631 1.0 0.2248274572035057 6 Q9UHG3,Q4KMQ2,P55011,P51798 4 +Positive regulation of striated muscle contraction 0.6706534422403712 1.8548220607011976 0.0636216406650467 1.0 0.2255457623144444 2 P05023 1 +Entry into host 0.4456420679249466 1.8537910934109665 0.0637690532081403 1.0 0.225702549704324 34 Q96KP1,P78310,O14786,Q8WTV0,Q9BTY2,P11279,Q9UPT5,O15118,P35613,Q14108 10 +L amino acid transport 0.63893417172414 1.8535042759760312 0.0638101138352451 1.0 0.2257261277557297 12 O75746,Q9H9B4,Q9Y619,Q15041,Q9UJS0,P30825 6 +Retinal ganglion cell axon guidance 0.7429587202681529 1.8523489269193696 0.0639757341782063 1.0 0.2260342228179214 3 O14786 1 +Estrogen metabolic process 0.7787241299139569 1.8519415717602012 0.0640342134921385 1.0 0.2260342228179214 6 O95470 1 +Meiotic spindle organization 0.6918153020160103 1.8519361480226784 0.064034992413672 1.0 0.2260342228179214 8 Q14674,Q12768,O14965,O95067,O14777,P30153 6 +Chemosensory behavior 0.7421053956238226 1.8483732485834463 0.0645483659220449 1.0 0.2272366025506104 3 Q13641 1 +Olfactory behavior 0.7421053956238226 1.8483732485834463 0.0645483659220449 1.0 0.2272366025506104 3 Q13641 1 +Organic hydroxy compound transport 0.4450719704569951 1.848370455112324 0.0645487697583568 1.0 0.2272366025506104 34 P30536,Q9BZF1,P61916,Q8WTV0,Q96SU4,O15118,P53985,P35610,Q14849,P22059 10 +Sulfur compound catabolic process 0.665294275867621 1.8475626301774888 0.064665639957731 1.0 0.227525967508113 10 P16278,P35610,P15586 3 +Protein o linked glycosylation via threonine 0.7414648380507552 1.8453880096287296 0.064981116092508 1.0 0.2280246437428008 3 Q8N4A0,Q10472 2 +Anterior posterior axis specification 0.6773199536318302 1.8421011217016896 0.065460359771756 1.0 0.2294609406101832 9 Q8N2A8,Q15363,O14965,Q9UK61,Q9Y2W6,Q5T9L3 6 +Antigen processing and presentation of peptide antigen 0.5954558157526639 1.839979424316544 0.0657712581661891 1.0 0.2300641852491808 15 Q9UIQ6,P10321,P01889,P04439,Q03519,Q9NZ08,Q03518 7 +Cellular sodium ion homeostasis 0.8142582725068956 1.839905713133623 0.0657820811157958 1.0 0.2300641852491808 4 Q96PU5,P55011 2 +Protein insertion into er membrane 0.6364127859441985 1.838962664469291 0.065920677715789 1.0 0.2300641852491808 12 P46379,Q9NPA0,O43681,Q15629,Q96A33 5 +C4 dicarboxylate transport 0.6766796092429711 1.8386956542624504 0.0659599629685758 1.0 0.2300641852491808 9 O75746,Q02978,P55011,Q9UBX3,Q9UJS0,Q15758 6 +Regulation of animal organ morphogenesis 0.6892332336991496 1.838552284515112 0.0659810649414645 1.0 0.2300641852491808 8 Q99623,Q8TAA9,P61586,Q9Y5V3 4 +Purine containing compound transmembrane transport 0.7330559466051442 1.838538776362434 0.0659830534347696 1.0 0.2300641852491808 7 P12235,P12236,O43808,Q8TB61 4 +Gliogenesis 0.3874955265782735 1.8295673409169655 0.0673146610613504 1.0 0.23321999198717 56 O75306,P30536,P42345,Q15022,Q9NQC3,O14744,P05067,P61586,P49770,O94901,P08670,P04083,Q96N66,Q96G23,P04062 15 +Amyloid precursor protein metabolic process 0.5302849868165826 1.8286866491527107 0.0674465636434318 1.0 0.23321999198717 20 Q9NQX7,O95197,P35610,Q15392,Q9Y287 5 +Folic acid metabolic process 0.7735767302173979 1.8285550746454864 0.0674662880110594 1.0 0.23321999198717 6 Q9H2D1 1 +Potassium ion homeostasis 0.8112837417101149 1.8271989090328649 0.0676698678531497 1.0 0.23321999198717 4 P55011,Q9BXP2 2 +L alpha amino acid transmembrane transport 0.6476425339092071 1.8241600682425791 0.0681278765396762 1.0 0.23369321790557 11 O75746,Q9UJS0,P30825,Q9Y619 4 +Fatty acid alpha oxidation 0.8097832852512408 1.8207842225999031 0.0686396635392192 1.0 0.2348739496021555 4 O14975,A1L0T0 2 +Regulation of anion transport 0.6326725059158183 1.817359825421705 0.0691620350233102 1.0 0.2364988399285885 12 P08183,O43865,P55011,Q15907 4 +Intracellular lipid transport 0.6050056424892842 1.8152180438686552 0.0694904078411986 1.0 0.2373743135106431 14 P23786,O14678,P61916,O15118,O43772,P22059 6 +Negative regulation of lymphocyte mediated immunity 0.7897905395228424 1.8148691082972317 0.0695440268884175 1.0 0.2374286548399722 5 P01889,P46108,P04439 3 +Locomotory behavior 0.4449633926279078 1.8115497551378883 0.0700557945250857 1.0 0.2383131797167508 33 O75844,P42345,P05067,O15118,P50897,P54802,P10253 7 +Protein processing 0.389990875050411 1.8112436234488205 0.0701031482289213 1.0 0.2383507039783327 47 Q8TCT9,Q99797,O75844,Q10713,P42892,O75503,P67812,Q92896,Q5JRX3,Q15392 10 +Dna methylation or demethylation 0.5096960655529207 1.8109619159785408 0.0701467470986672 1.0 0.2383754295502093 23 O75844,Q9Y2W6,Q8N2A8 3 +Negative regulation of natural killer cell mediated immunity 0.8073158658569769 1.8102284828040105 0.0702603623439694 1.0 0.2386379387686996 4 P01889,P04439 2 +Phospholipid transport 0.5906495872439028 1.8097315624888848 0.0703374254396773 1.0 0.2386750588076933 15 P08183,Q4KMQ2,Q9BZF1,Q8WTV0,P22059,Q14108,Q96GC9 7 +Porphyrin containing compound metabolic process 0.5625438038344639 1.809077920864717 0.0704388986833119 1.0 0.2387804260735735 17 P30536,P09601,P30519 3 +Cellular monovalent inorganic cation homeostasis 0.4959054881862965 1.808208557715567 0.0705740472228573 1.0 0.2387804260735735 25 P55011,P05023,Q15904,O75503,Q9Y487,Q96PU5,Q93050,P50897,Q92544,Q8N511,Q9Y6M7 11 +Negative regulation of cytokine production 0.4529918410884319 1.8078610680829472 0.0706281263638077 1.0 0.2387804260735735 31 P30536,P31483,P04083,P09601,P04062 5 +Antigen processing and presentation of peptide antigen via mhc class i 0.6037800290013882 1.8077146446539816 0.0706509241356554 1.0 0.2387804260735735 14 Q9UIQ6,P10321,P01889,P04439,Q03519,Q9NZ08,Q03518 7 +Regulation of steroid biosynthetic process 0.6579239172916138 1.8072835479353175 0.0707180798920383 1.0 0.2387804260735735 10 P30536,P05023,P16435,Q9UBM7,Q13510,O75477 6 +Natural killer cell mediated immunity 0.630874152142576 1.80695978295948 0.0707685500469508 1.0 0.2387804260735735 12 P33176,P11279,P01889,P46108,P04439,P07437 6 +Regulation of lipoprotein metabolic process 0.787787877627719 1.8060332399054968 0.0709131476046516 1.0 0.239122340483928 5 P04062 1 +Positive regulation of cellular amide metabolic process 0.3767386832476644 1.8046701204081264 0.0711263181607011 1.0 0.2396793113725162 66 P42345,Q9H2U1,P98179,Q00839,P51116,P67809,P11940,Q06787,P61586,Q9Y2R0,Q14103,P51114,Q9NWS8,Q567V2,P08670,Q08211,Q07666,O60506 18 +Cellular response to copper ion 0.7326984730579047 1.8044609566184415 0.0711590745451413 1.0 0.2396793113725162 3 P05067 1 +Male meiotic nuclear division 0.7682433076108526 1.8042769801406349 0.0711878966572743 1.0 0.2396793113725162 6 Q13315,Q9Y2W6 2 +Regulation of cell maturation 0.6595682613768815 1.797864741088947 0.0721984447856591 1.0 0.2424596697459035 2 O14965 1 +Regulation of oocyte maturation 0.6595682613768815 1.797864741088947 0.0721984447856591 1.0 0.2424596697459035 2 O14965 1 +Positive regulation of cell maturation 0.6595682613768815 1.797864741088947 0.0721984447856591 1.0 0.2424596697459035 2 O14965 1 +Mitochondrial protein processing 0.7665709478405986 1.7966547019169543 0.072390454418489 1.0 0.242925801120851 6 Q99797 1 +Positive regulation of erad pathway 0.7309425165593169 1.796247010387024 0.0724552412041679 1.0 0.2429490509870975 3 P46379 1 +Negative regulation of regulated secretory pathway 0.7852516019629867 1.794834228505923 0.072680115549097 1.0 0.2432059756415985 5 P09601 1 +Cellular response to insulin like growth factor stimulus 0.7300083813577988 1.7918752057260807 0.0731529584670647 1.0 0.2445388249928062 3 Q9BSK2 1 +Skin development 0.3999185829811434 1.7872597137530593 0.0738955220496964 1.0 0.2461433582183288 42 O75844,P04083,Q15392,Q8TAF3,P04062 5 +Atp synthesis coupled electron transport 0.4212416267127226 1.7845674328543646 0.0743315078584139 1.0 0.2467237872627696 38 O75306,P51970,Q9Y6M9,P03886,P08574,Q9UDW1,Q7KZN9,P13073,O43676,O14949,P00403 11 +Ventricular septum morphogenesis 0.7284456961905146 1.784558446030472 0.0743329666898042 1.0 0.2467237872627696 3 O96028 1 +Atp transport 0.7821897810218897 1.7813016734418172 0.0748631812694256 1.0 0.247981926042388 5 Q6NUK1,P12236,O43808,P12235 4 +Regulation of glial cell proliferation 0.7819729602802576 1.780342840764989 0.0750198700200881 1.0 0.248375573699202 5 P30536 1 +Neuron projection regeneration 0.6389991975769758 1.7755176410201676 0.0758124553595778 1.0 0.2491143375410864 11 P30536,P00374,Q96G23 3 +Regulation of t cell mediated cytotoxicity 0.7805384492374193 1.7739973250757244 0.0760635927704485 1.0 0.2495646478798415 5 P01889,P04439 2 +Positive regulation of t cell mediated cytotoxicity 0.7805384492374193 1.7739973250757244 0.0760635927704485 1.0 0.2495646478798415 5 P01889,P04439 2 +Oogenesis 0.5280417965895478 1.7729100444502366 0.07624361400001 1.0 0.2499053921418909 19 Q8N2A8,Q12768,P62753,O14965,Q9H6S0,Q13315,Q9Y2W6,Q96MU7,Q9UHI6,P30153 10 +Cellular response to nutrient 0.7603886625992813 1.7684380621256262 0.0769876981903661 1.0 0.2517785464815394 6 P20020,P09601 2 +Phospholipid biosynthetic process 0.3796634348447244 1.760779055359746 0.0782758061470529 1.0 0.2542801187806741 60 O75874,Q13315,Q14457,O15269,Q10713,O15270,O15228,Q96N66,P22059,Q6IAN0,O43292,Q86YN1,Q9BTU6,Q9NPH0,Q9UG56,P52429,O60762,P48651,Q9NUQ2,Q8TBX8,Q8NF37,Q9H490 22 +Serine transport 0.722497811496941 1.756672062398844 0.0789737221268351 1.0 0.2560730622421701 3 Q9H9B4,Q96NB2 2 +Gene silencing by rna 0.385398393265615 1.7566128113217814 0.0789838277930741 1.0 0.2560730622421701 46 O75844,Q9HAV4,Q9HCE1,P11940,Q06787,Q01085,Q9Y2W6,P51114,O75569,P22626,Q9BWF3 11 +Lipid translocation 0.7757621130445815 1.7528474129166454 0.0796282022069259 1.0 0.2573991442767723 5 P08183,Q4KMQ2 2 +Regulation of membrane lipid distribution 0.7757621130445815 1.7528474129166454 0.0796282022069259 1.0 0.2573991442767723 5 P08183,Q4KMQ2 2 +Lung alveolus development 0.7215764773976812 1.7523472065904255 0.079714123413153 1.0 0.2574865091964711 3 O60476 1 +Circadian rhythm 0.3845068434750052 1.749976157058741 0.0801224280235575 1.0 0.2581448124069545 48 P42345,Q00839,P43490,P23246,Q03164,P54646,O14744,Q9UNS1,P78527,Q14103,Q9Y5V3,P54802,O75592,Q9BWF3 14 +Positive regulation of cysteine type endopeptidase activity 0.4669153922318321 1.749695255259908 0.0801709128694245 1.0 0.2581448124069545 28 Q96A26,O14737,P61586,Q9NZJ7,Q9BXK5,Q9P0J0 6 +Negative regulation of cell killing 0.7748419481402803 1.748769031273638 0.0803309519864372 1.0 0.2581448124069545 5 P01889,P04439 2 +Vascular process in circulatory system 0.4343363821487713 1.7458751783818842 0.0808326438775299 1.0 0.2595028420373541 34 P20020,P08183,P42892,Q9HB40,P61586,P53985,Q16625,O60568 8 +Negative regulation of immune effector process 0.6466897092098899 1.7456438967549854 0.0808728494901149 1.0 0.2595049576303835 10 P01889,P46108,P04439,P04083,P09601 5 +Oocyte construction 0.7192521239546974 1.7414302740869498 0.0816081854037809 1.0 0.2608440879783781 3 Q9Y2W6 1 +Regulation of morphogenesis of a branching structure 0.7903993096424906 1.7376260238316228 0.0822767312583683 1.0 0.2614668343176974 4 Q9Y5V3,Q9NQC3 2 +Cellular macromolecule localization 0.2806564418739444 1.7369847290906186 0.0823898663789808 1.0 0.2614668343176974 587 Q99623,P30536,P52789,P24390,Q9NS69,O14786,O14965,Q92974,O14777,O60830,Q13107,Q9UGP8,Q9NVN8,Q13190,Q15154,Q9HD20,P43307,Q7Z3B4,Q99567,Q96DY7,O43681,Q9Y5J7,Q14108,O43615,O60725,Q9H2U1,P55786,Q99959,Q99595,Q9UK61,Q9H223,Q8NFQ8,Q9C0E2,Q5JRX3,Q99523,Q9HD45,Q13438,Q8N1F7,Q9Y2T2,Q9HAV4,O43731,O15260,Q00839,Q8N4H5,Q9Y282,P46934,Q9HD47,O14936,O15118,Q14BN4,Q15629,P52294,Q08211,Q9Y584,O95487,Q9H490,Q9Y5L4,Q8TD16,Q9P2W9,P49354,P11279,O43805,O00264,Q9Y6C9,Q9Y5X2,Q9UBN7,Q9HCU5,Q5SRE5,P35658,Q9P0J0,O14773,O14737,Q99729,Q15070,Q9Y5J9,O43292,O60684,O14925,Q92973,Q96PU5,P10619,Q16543,Q9Y6X3,O95391,Q9Y5M8,P13473,P57105,Q92544,P46379,O00560,P35613,Q9Y512,Q15907,Q8TCT9,Q99797,Q10713,P14625,Q14168,Q969Q5,P31483,A0AVF1,O15397,Q96L92,Q13535,Q16625,Q96RL7,Q9NQC3,Q9BUN8,O94901,Q4J6C6,Q96JB5,Q96HY6,Q96A33,Q13641,Q8TB36,Q9UBV2,P67809,Q13315,Q8IZ07,O95831,Q9P2S5,P33176,Q13277,Q9UPT5,Q9UH99,P50402,Q5T9L3,Q9BZF1,Q9Y3B3,O43865,Q96D46,Q76FK4,Q15904,Q5HYI8,Q9NQG6,P53350,Q9Y5V3 137 +Regulation of modification of synaptic structure 0.7901680590679434 1.736630806952674 0.0824523581563492 1.0 0.2614668343176974 4 Q9UQB8,P61586 2 +Regulation of modification of postsynaptic structure 0.7901680590679434 1.736630806952674 0.0824523581563492 1.0 0.2614668343176974 4 Q9UQB8,P61586 2 +Very long chain fatty acid catabolic process 0.7718976078448706 1.7357108290028451 0.0826149777782889 1.0 0.2614668343176974 5 O14975,O14678,Q15067 3 +Locomotor rhythm 0.7897905650131158 1.7350060579508937 0.0827397322059626 1.0 0.2614668343176974 4 P54802 1 +Macroautophagy 0.3326536161575145 1.7344099444404093 0.0828453718645065 1.0 0.261605141912097 113 Q99623,P21796,P16615,P04062,Q14457,O15269,O15270,Q9UPT5,Q9Y487,Q9Y6I9,P09601,Q96GC9,P42858,P54646,P12235,Q93050,P42345,Q16543,P46934,P13473,O15118,Q8TBX8,P27544,Q96HY6 24 +Dendrite arborization 0.7177134616074141 1.7341987547820212 0.0828828238395686 1.0 0.261605141912097 3 Q13641 1 +T cell differentiation involved in immune response 0.7893373512286566 1.7330551559294187 0.0830858658699038 1.0 0.2621199287684178 4 P04083 1 +Ph reduction 0.6041819211056771 1.7319283224987898 0.0832863252522146 1.0 0.2623485492387725 13 Q8N511,O75503,Q9Y487,P50897 4 +Cell surface receptor signaling pathway involved in cell cell signaling 0.3514383383511801 1.7288357037046422 0.0838385041056264 1.0 0.26348096932046 75 Q8TAA9,Q13641,Q96K76,P54646,P05067,Q9H2V7,P61586,P50402,P48729,Q9UQB8,P52294,Q6DKJ4,Q14168,Q5T9L3 14 +Maintenance of location in cell 0.3820808763576208 1.724490907748405 0.0846192589462706 1.0 0.2654261841326137 49 P30536,P42858,O43292,O43731,P52789,P24390,Q96RL7,P14625,Q9UH99,O94901,O95202,P10253,Q13438 13 +Negative regulation of tyrosine phosphorylation of stat protein 0.6443990665110916 1.7195147332447545 0.0855206872603913 1.0 0.2676140914652779 2 P30153 1 +Cellular response to extracellular stimulus 0.3818990478791497 1.7174866384871992 0.0858902937014407 1.0 0.268418809584978 47 P20020,P42345,Q8TB36,P09601,P54646,P13473,Q9H773,Q9Y4P3,P21964,P04062,Q14457 11 +Apoptotic cell clearance 0.6151022311399515 1.715393185928772 0.0862731638677924 1.0 0.2690705804659954 12 Q8WTV0,P04083,Q14457 3 +Regulation of oxidative phosphorylation 0.6655029228446384 1.7148888311294666 0.0863656107576245 1.0 0.2691329146981797 8 P14406,Q9BSK2 2 +Respiratory chain complex iv assembly 0.7486321778479881 1.714615505028832 0.0864157441221271 1.0 0.2691329146981797 6 Q9Y2R0,Q15070 2 +Pyramidal neuron differentiation 0.7848631599303943 1.7137809251296774 0.0865689678959356 1.0 0.2692253873616727 4 P04062 1 +Activation induced cell death of t cells 0.7130745336106731 1.712373639640708 0.086827833716977 1.0 0.2697747371452665 3 P62753 1 +Gland development 0.3477794905039723 1.7108718680623942 0.0871047688620165 1.0 0.2702512970555805 76 Q99623,P30536,P52789,O14786,O14965,Q13315,Q14103,P04083,Q9UGP8,P00403,O75844,P07602,Q13505,P09601,Q5T9L3,O14744,Q9NZJ7,Q15418,Q9NQC3,P62841,Q96JB5,P35610 22 +Protein localization to nuclear envelope 0.7064345248140834 1.708973767816527 0.0874558086976478 1.0 0.2704961831830109 7 Q8NFQ8,P53350,Q9BZF1 3 +Ether metabolic process 0.6642720680343992 1.7084435321332354 0.0875540756361308 1.0 0.2704961831830109 8 Q6IAN0,P07099,Q8WVX9,O15228,P49327 5 +Excretion 0.7654846221205371 1.707226550650088 0.0877799519078399 1.0 0.2709369917305953 5 P09601 1 +Cellular response to mineralocorticoid stimulus 0.7110978067502833 1.7030633688534045 0.0885562101676888 1.0 0.2723082713778699 3 P20020 1 +Adp transport 0.7819614711033117 1.7012668027519235 0.0888928987157604 1.0 0.2724531007350262 4 P12235,P12236,O43808 3 +Positive regulation of mitophagy 0.7819614711032955 1.7012668027518536 0.0888928987157735 1.0 0.2724531007350262 4 P12235,P21796,P27544 3 +Calcium import into the mitochondrion 0.763908275797961 1.7002161979026122 0.089090266563141 1.0 0.2726629178656489 5 P21796 1 +Protein localization to endoplasmic reticulum 0.421882272347442 1.7000122940766025 0.0891286130481281 1.0 0.2726629178656489 36 P46379,O43731,O43292,P24390,Q9NQC3,Q9Y5M8,O43681,Q15629,Q96HY6,Q9UGP8 10 +Intracellular transport of virus 0.7630298085000363 1.6963079877602534 0.0898275685520342 1.0 0.2741643504077712 5 O60684 1 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.6118275174225882 1.6963040841560868 0.0898283074332075 1.0 0.2741643504077712 12 Q9H2U1,Q00839,P67809,P11940,Q14103,O60506 6 +Isocitrate metabolic process 0.7441488418828074 1.6940355000505098 0.0902585374166502 1.0 0.274448937958749 6 O75874 1 +Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway 0.639148191365235 1.6922897853485548 0.0905907344740395 1.0 0.274448937958749 2 P23634 1 +Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway 0.639148191365235 1.6922897853485548 0.0905907344740395 1.0 0.274448937958749 2 P23634 1 +Positive regulation of renal sodium excretion 0.6391481913652346 1.6922897853485526 0.0905907344740399 1.0 0.274448937958749 2 Q9Y5X3 1 +Renal sodium excretion 0.6391481913652346 1.6922897853485526 0.0905907344740399 1.0 0.274448937958749 2 Q9Y5X3 1 +Negative regulation of calcium ion dependent exocytosis 0.6391481913652343 1.6922897853485526 0.0905907344740399 1.0 0.274448937958749 2 O00186 1 +Renal tubular secretion 0.6391481913652346 1.6922897853485526 0.0905907344740399 1.0 0.274448937958749 2 Q9Y5X3 1 +Regulation of excretion 0.6391481913652346 1.6922897853485526 0.0905907344740399 1.0 0.274448937958749 2 Q9Y5X3 1 +Regulation of renal system process 0.6391481913652346 1.6922897853485526 0.0905907344740399 1.0 0.274448937958749 2 Q9Y5X3 1 +Base conversion or substitution editing 0.7080163995730657 1.688538179571919 0.0913079663996876 1.0 0.2752881309693319 3 Q96DE0 1 +Cellular modified amino acid metabolic process 0.3715674346685424 1.688115258796952 0.0913891059060572 1.0 0.2752881309693319 64 P23786,O75874,O15217,O60725,Q9NVH6,Q8TB36,Q9BZF1,P16435,P48651,P00374,Q92820,Q06520,Q9H2D1,Q9UHG3,Q8NCC3,O60568 16 +Lysosomal transport 0.3793807842444388 1.68707540599022 0.0915888534278022 1.0 0.2752881309693319 44 P07602,P46934,Q96L92,P13473,O15118,Q14108 6 +Urogenital system development 0.3789768554705077 1.6853426968473768 0.091922472498946 1.0 0.2752881309693319 48 P46379,O75844,Q12769,O76024,P07602,P61586,Q9NZJ7,P04083,O95470,Q9Y5V3,P35610 11 +Necroptotic signaling pathway 0.6373978996499485 1.6832034970800749 0.0923357040790977 1.0 0.2756628253717195 2 P49327 1 +Blood vessel endothelial cell migration 0.4865472897610676 1.6804200925369894 0.0928756094549041 1.0 0.2770226132923095 24 O94813,O14786,Q8WTV0,P06576,P61586,P42785,P04083,P09601 8 +Leukocyte mediated cytotoxicity 0.5698444851735497 1.6779839559762495 0.0933502311545291 1.0 0.2780591088679165 15 P33176,P11279,P01889,P46108,P04439,Q9NUQ9,P07437 7 +Endoplasmic reticulum membrane organization 0.6574653808092067 1.672748669415666 0.0943767837071813 1.0 0.2796602377245781 8 Q8NHH9,Q9P2W9,Q15041,Q9NQC3 4 +Vacuolar acidification 0.6334304563299521 1.6725333353384193 0.0944192001190291 1.0 0.2796602377245781 10 Q8N511,O75503,Q9Y487,P50897 4 +Proton transporting two sector atpase complex assembly 0.7573838756824814 1.6711649984260757 0.0946890916976825 1.0 0.2801396842742079 5 Q8N511,Q15070 2 +Regulation of complement activation 0.7041805677582924 1.6704368349674552 0.0948329669167096 1.0 0.2801863705121334 3 Q99623 1 +Regulation of humoral immune response 0.7041805677582924 1.6704368349674552 0.0948329669167096 1.0 0.2801863705121334 3 Q99623 1 +Complement activation 0.7041805677582924 1.6704368349674552 0.0948329669167096 1.0 0.2801863705121334 3 Q99623 1 +Negative regulation of secretion 0.5133299907108968 1.6670152513143552 0.095511372282361 1.0 0.2814253331609137 19 P09601,P04083,Q06787 3 +Nuclear pore organization 0.619771573915023 1.6666737948242092 0.0955792863766191 1.0 0.2814253331609137 11 Q7Z3B4,Q9BTX1,Q8N1F7,Q9NQC3 4 +Mitochondrial genome maintenance 0.6323263970662727 1.6664289492780358 0.0956280088067609 1.0 0.2814253331609137 10 P12235,Q9BSK2 2 +Regulation of vacuole organization 0.6196778312806259 1.6661411028566049 0.095685313517857 1.0 0.2814253331609137 11 Q8TBX8,Q14108 2 +Cardiac muscle cell action potential 0.5131820748095258 1.6659465068387678 0.095724069432362 1.0 0.2814253331609137 19 P78310,P05023,Q9HD47,Q99959,P16615,Q96PU5 6 +Protein o linked mannosylation 0.7553284671532527 1.662001185156372 0.096512536852066 1.0 0.2833625354913904 5 O60762,Q6ZXV5,Q8NAT1,O43505 4 +Protein mannosylation 0.7553284671532527 1.662001185156372 0.096512536852066 1.0 0.2833625354913904 5 O60762,Q6ZXV5,Q8NAT1,O43505 4 +Positive regulation of ion transport 0.3770897413393115 1.6614859681765737 0.0966158847494671 1.0 0.2835391036341697 47 P20020,P08183,Q4KMQ2,P30536,P42858,P55011,O76024,P27695,P33176,Q99959,O14936,Q15041,O43865,Q96GC9 14 +Negative regulation of double strand break repair via nonhomologous end joining 0.6324387397899723 1.6574292087825089 0.097432730160087 1.0 0.2847900112741608 2 Q9BRJ7 1 +Mononuclear cell differentiation 0.3759949428067234 1.6560491077320094 0.0977118743525116 1.0 0.2854787709266167 50 P42345,P24390,O15360,O96005,P61586,Q13315,P01889,P04083,P04062 9 +Positive regulation of release of cytochrome c from mitochondria 0.7351925382543905 1.6528367714639915 0.0983640881606973 1.0 0.2864914099025724 6 Q96A26 1 +Bleb assembly 0.7703113637835031 1.65091617077265 0.0987556933849269 1.0 0.28657222309157 4 Q9NR77 1 +Protein localization to lysosome 0.5525042846076503 1.650904291372358 0.0987581194295015 1.0 0.28657222309157 16 Q9NQC3,P46934,P13473,Q99523,Q14108 5 +Transmembrane receptor protein tyrosine phosphatase signaling pathway 0.6303967327888056 1.6468037546557912 0.0995983893780154 1.0 0.2885495060037693 2 P10586 1 +Neutrophil differentiation 0.7691185055458137 1.6457513788404747 0.0998149562508676 1.0 0.2889218098448141 4 Q6IAN0,Q8N5M9,Q14739 3 +Rhythmic behavior 0.7515726486715791 1.6452421894619034 0.0999198763227267 1.0 0.2890503210897925 5 P54802 1 +Smad protein signal transduction 0.6516065965900304 1.6419563106931347 0.1005990586196219 1.0 0.2908066179127573 8 Q9UIQ6,P08670,Q96PK6 3 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.6921787549661819 1.6390925595992707 0.1011939843827318 1.0 0.2920655129787563 7 Q16543,P52789,P04062 3 +Hydrogen peroxide biosynthetic process 0.6973901322876671 1.6383401560011717 0.1013507553473322 1.0 0.2922051058294924 3 P00403 1 +Adult locomotory behavior 0.5371428518244973 1.6379166691563511 0.1014390781895129 1.0 0.2922051058294924 17 O75844,P50897,O15118 3 +Protein transmembrane import into intracellular organelle 0.5881117091049819 1.635321616435362 0.101981644397763 1.0 0.2932530896310784 13 O14925,O60830,Q99595,O95831 4 +Phosphatidylglycerol metabolic process 0.6264947028952854 1.6341447456478686 0.1022284613004991 1.0 0.293576876610011 10 Q99623,Q6UWP7,Q9NP80,Q96BW9,Q8NF37,Q8NCC3 6 +Regulation of leukocyte mediated cytotoxicity 0.6384368120261986 1.6337071768847498 0.1023203506842871 1.0 0.29371222274291 9 P01889,P46108,P04439,Q9NUQ9 4 +Negative chemotaxis 0.6962363505020885 1.6328800425510812 0.1024942283191423 1.0 0.2939541635621556 3 P61586 1 +Monocarboxylic acid transport 0.6901372328525178 1.629059008723733 0.1033005277379555 1.0 0.2952343480036864 7 Q9NP80,P53985,P04083 3 +Retrograde vesicle mediated transport golgi to endoplasmic reticulum 0.4599022711102888 1.6273332930839526 0.1036663306169718 1.0 0.2958823713942234 27 Q8TD16,P42858,O43731,Q9P2W9,Q6NUQ1,Q9H4A6,P24390,Q9Y282,Q12907,A2RRP1,P49755,O15258 12 +Embryonic pattern specification 0.6486414726233432 1.6263491493275393 0.103875401743962 1.0 0.296135782137518 8 O14786,Q9Y2W6,Q8N2A8,Q9UK61 4 +Regulation of cardiac muscle cell action potential 0.6126378929928753 1.6260837717987375 0.1039318357608509 1.0 0.296135782137518 11 Q9HD47,Q99959,P16615 3 +Lipoprotein biosynthetic process 0.5863280358051369 1.6245606190913655 0.1042562140201792 1.0 0.2969311095487918 13 O60762,O43292,Q5HYI8,P04062 4 +T cell differentiation in thymus 0.6365847872043034 1.6237058289455757 0.1044386064051723 1.0 0.2971925998398702 9 P78527,Q5HYI8,O96005,P04062 4 +N glycan processing 0.763202454344921 1.6201116311304402 0.1052082993535368 1.0 0.2979357452626758 4 O60476 1 +Proteoglycan metabolic process 0.6882834302315536 1.619942641286957 0.1052445988294548 1.0 0.2979357452626758 7 Q7LGA3,Q9UL01 2 +Proteoglycan biosynthetic process 0.6882834302315536 1.619942641286957 0.1052445988294548 1.0 0.2979357452626758 7 Q7LGA3,Q9UL01 2 +Positive regulation of nitric oxide synthase activity 0.7620026803397832 1.6149069928800208 0.106330837679798 1.0 0.2991965826721641 4 P00374 1 +Heparan sulfate proteoglycan biosynthetic process 0.7266900992707295 1.6136243952743805 0.1066089220539541 1.0 0.299472494228616 6 Q7LGA3,Q9UL01 2 +Heparan sulfate proteoglycan metabolic process 0.7266900992707295 1.6136243952743805 0.1066089220539541 1.0 0.299472494228616 6 Q7LGA3,Q9UL01 2 +Bundle of his cell to purkinje myocyte communication 0.726557159539136 1.613010539880409 0.1067422179491031 1.0 0.299590433781871 6 Q9HD47 1 +Regulation of deacetylase activity 0.6918033521270104 1.6118845637526855 0.1069870618297823 1.0 0.3001492517003128 3 P49354 1 +Regulation of sodium ion transmembrane transport 0.5593797480484417 1.6112538727540653 0.1071244001047402 1.0 0.3004061168749168 15 Q9HD47,P46934 2 +Cellular response to leucine starvation 0.6911297095836465 1.608691762709745 0.1076837578711602 1.0 0.3017254487444085 3 P42345 1 +Cerebral cortex radially oriented cell migration 0.6451362197035295 1.607879555758409 0.1078615602111841 1.0 0.3019571493625383 8 Q96N66,Q9NQC3 2 +Telencephalon glial cell migration 0.6451362197035295 1.607879555758409 0.1078615602111841 1.0 0.3019571493625383 8 Q96N66,Q9NQC3 2 +Chemokine production 0.6335375884116474 1.6072368718798284 0.1080024164711277 1.0 0.3020024614552307 9 P09601 1 +Dna templated transcription termination 0.6856613885116024 1.6070397036660438 0.1080456587698535 1.0 0.3020024614552307 7 O75844,Q16637,O14744 3 +Negative regulation of cellular catabolic process 0.3287999882375389 1.6069659496844757 0.1080618377776412 1.0 0.3020024614552307 93 P46379,P30536,Q14011,P67809,O00560,P11940,Q14103,P98175,Q14457,Q99729,Q13151,P07910,Q9Y2S7,P09601,O60506,Q9H2U1,Q06787,Q92804,P42345,P10619,Q00839,P35637,O15118,Q08211,Q07820,Q96JB5,Q96HY6,Q9NNW5 28 +Chloride transport 0.5830567650837741 1.6048060864367133 0.1085364861163085 1.0 0.3024273553695186 13 Q9C0H2,P08183,P30536,Q9UHG3 4 +Establishment of protein localization 0.2768991164607935 1.6043520626600287 0.1086364712214054 1.0 0.3024490980716429 561 Q99623,P30536,P52789,P24390,Q9NS69,Q92974,O60830,P50897,Q9UGP8,Q13190,Q15154,Q32P28,Q9HD20,P43307,Q12768,Q7Z3B4,Q99567,O43681,Q9Y5J7,Q14108,O43615,A6NIH7,O60725,P55011,P55786,O15127,Q99595,Q9C0E2,Q5JRX3,Q99523,Q13438,Q9BTX1,Q9Y2T2,Q8N1F7,Q9HAV4,O43731,O15260,Q8N4H5,Q9Y282,P46934,Q9HD47,Q8NFH4,O15118,Q15629,P52294,Q07820,Q9Y584,O95487,Q16836,Q9Y5L4,Q8TD16,Q9P2W9,P11279,Q9Y5X2,Q9UBN7,Q9HCU5,P04083,Q5SRE5,P35658,Q9P0J0,P07900,Q96KP1,O14737,P00367,O95249,Q15070,Q96GC9,Q9Y5J9,O60684,O14925,Q92973,Q9H7B4,Q16850,Q03519,Q03518,Q96PC5,P10619,Q16543,O95391,Q9Y5M8,P13473,P57105,Q92544,P46379,O00560,P53985,Q9Y512,Q15907,Q8TCT9,Q99797,Q10713,P14625,Q14168,P22059,P49321,Q96KC8,Q969Q5,A0AVF1,O15397,Q96L92,O96028,P41208,Q96RL7,Q9BUN8,Q4J6C6,Q96A33,Q8TB36,Q9UBV2,O95831,P33176,Q13277,Q9UPT5,P50402,Q5T9L3,Q6NUQ1,Q9Y3B3,O43865,Q96D46,Q12769,Q15904,Q5HYI8,Q9NQG6,P53350,Q8N5M9 124 +Modification of postsynaptic actin cytoskeleton 0.7421533214125502 1.603134548898182 0.1089049518077693 1.0 0.3025847830214328 5 Q9UQB8,P61586 2 +Adaptive immune response 0.3720919481871915 1.6030855574479592 0.1089157661530972 1.0 0.3025847830214328 47 P42345,Q9NZ08,Q96FV9,P10321,P01889,Q9UQ84,O96028,Q03519,P04083,Q6P179,Q9NUQ9,Q96FZ2,Q03518,P04439 14 +Regulation of cell killing 0.6203620646696361 1.6001235607126163 0.1095711751937829 1.0 0.3034793812933359 10 P01889,P46108,P04439,Q9NUQ9 4 +Membrane protein ectodomain proteolysis 0.632191881388063 1.5999586272095767 0.1096077619117961 1.0 0.3034793812933359 9 Q8TCT9,Q9NZ08,Q92542,P38159 4 +Protein exit from endoplasmic reticulum 0.4821067493861749 1.5971053072162948 0.110242235369887 1.0 0.3049787303951092 23 Q8TCT9,O15260,Q9UBV2,Q9HD47,Q9BUN8,P14625,P49257,Q9HCU5,Q92544,Q13438 10 +Regulation of transforming growth factor beta activation 0.6201866977829705 1.5935724014821753 0.1110318400270777 1.0 0.3061306446460858 2 P06756 1 +Transforming growth factor beta activation 0.6201866977829705 1.5935724014821753 0.1110318400270777 1.0 0.3061306446460858 2 P06756 1 +Bone mineralization 0.6420149991280539 1.5914162679692287 0.111515925601703 1.0 0.306626766037835 8 O75844,P20020,Q4KMQ2 3 +Cartilage development 0.5560936312641083 1.590241123424997 0.1117804642082924 1.0 0.306626766037835 15 O75844,P16435,Q92896,Q96HY6,Q15043 5 +Negative regulation of nitric oxide metabolic process 0.7392685779742445 1.59021756023778 0.1117857736123464 1.0 0.306626766037835 5 P30536,P06280 2 +Cell volume homeostasis 0.7215963270498388 1.5900877386615755 0.1118150293859145 1.0 0.306626766037835 6 Q4KMQ2,P55011,Q9NUT2 3 +Maintenance of protein location 0.4215666756319938 1.5898420396907336 0.1118704150931115 1.0 0.306626766037835 33 P30536,O43292,O43731,P52789,P24390,Q96RL7,Q9UH99,O94901,Q13438 9 +Cranial nerve development 0.7390504150894323 1.589240304303369 0.1120061502884319 1.0 0.306626766037835 5 Q9H061 1 +Regulation of mitophagy 0.6818510322739396 1.5882715324296877 0.1122249518445503 1.0 0.3069696265126885 7 P12235,P21796,P27544 3 +Retina morphogenesis in camera type eye 0.7554583743824033 1.5864896316555612 0.1126282823007343 1.0 0.3075600451341733 4 P54802 1 +Glial cell migration 0.5797744485313265 1.5849610662749245 0.1129751804671799 1.0 0.3081890811741809 13 P30536,Q96N66,Q96G23,Q9NQC3 4 +Behavioral response to pain 0.6861041399171901 1.584853902954949 0.1129995320489301 1.0 0.3081890811741809 3 P30536 1 +Response to pain 0.6861041399171901 1.584853902954949 0.1129995320489301 1.0 0.3081890811741809 3 P30536 1 +Protein targeting to lysosome 0.5795903433951964 1.5838472694481924 0.113228479430413 1.0 0.3084289257045954 13 Q99523,P13473,Q14108,P46934 4 +Tricarboxylic acid metabolic process 0.6173833203915261 1.583573705761634 0.1132907615045701 1.0 0.3084705298726097 10 O75874 1 +Regulation of entry of bacterium into host cell 0.7539629996047853 1.579989778456979 0.1141092073258946 1.0 0.3102684833556146 4 Q9BTY2,Q9UPT5 2 +Response to cobalt ion 0.6172695449241544 1.578333137111331 0.1144890970114036 1.0 0.3107020076876884 2 P42574 1 +Response to nutrient 0.4166836493500959 1.5757298748040671 0.1150880694309628 1.0 0.312069384961148 34 P20020,P30536,P42345,P16435,P53985,O15228,P09601,Q14457 8 +Sterol biosynthetic process 0.4605059215155725 1.5749685253847154 0.1152637097992732 1.0 0.3124165484109174 26 P37268,P54646,Q16850,Q15392,Q15800,Q14534,Q14739 7 +Regulation of toll like receptor 3 signaling pathway 0.6158109684947484 1.57070871700169 0.116250323480024 1.0 0.3137945794635615 2 O75955 1 +Protein localization to membrane raft 0.6158109684947484 1.57070871700169 0.116250323480024 1.0 0.3137945794635615 2 O75955 1 +Toll like receptor 3 signaling pathway 0.6158109684947484 1.57070871700169 0.116250323480024 1.0 0.3137945794635615 2 O75955 1 +Positive regulation of fatty acid transport 0.6155192532088749 1.569183457010148 0.1166051977622046 1.0 0.3140475033667351 2 P14174 1 +Pteridine containing compound metabolic process 0.5270242033920483 1.5691754043034822 0.1166070735990385 1.0 0.3140475033667351 17 Q99707,P00374,Q92820,Q9H2D1,P34896 5 +Cerebral cortex cell migration 0.6026323938634327 1.5689813246586952 0.1166522906300275 1.0 0.3140475033667351 11 Q96N66,P61586,Q9NQC3 3 +Regulation of protein tyrosine phosphatase activity 0.6146441073512319 1.5646069331856132 0.1176751022285713 1.0 0.3163392137746355 2 P04899 1 +Sphingomyelin metabolic process 0.7155105413576364 1.5619258297411929 0.1183054627499364 1.0 0.3169948740567918 6 O15269,O15270,P22059 3 +Response to testosterone 0.6010589465586789 1.5599842998488849 0.118763591409797 1.0 0.3175787593781834 11 P30536,Q13126,P04062 3 +Skeletal system morphogenesis 0.4882341659908463 1.558081771986831 0.1192138650981231 1.0 0.3185184783281287 21 O75844,P16435,Q92896,O75569,O95470,Q8TAF3 6 +Ion homeostasis 0.3232660020062029 1.5576118526671523 0.1193252872697494 1.0 0.3186864204575074 109 P30536,P20020,P16615,O95202,P50897,Q8N511,Q9Y6M7,Q9HD20,P30519,P14625,Q9Y487,Q8NE01,P09601,Q15043,P42858,P55011,P05067,Q96PU5,Q9BXP2,Q6P4Q7,Q8IYU8,Q93050,O76024,P05023,Q16891,Q9HD47,Q15904,O75503,Q92544,Q96A33 30 +Neuromuscular process controlling balance 0.575208509030347 1.557317093639079 0.1193952189681444 1.0 0.3187356415871183 13 O14773,P17900,P05067 3 +Regulation of mrna processing 0.3256268211289038 1.5565383516256843 0.119580130319979 1.0 0.3189775671380904 92 P21127,Q14011,P61978,P14866,P52756,Q96MU7,P98175,Q9BWF3,P98179,Q13595,Q15427,Q07666,Q9H2U1,P62995,P31483,Q96EP5,Q06787,P26368,P51114,P22626,O43865,P38159,Q00839,P51116,Q07021,Q08211,Q9UHX1 27 +Organelle disassembly 0.3669743043032235 1.5562800508582473 0.1196415130497599 1.0 0.319011624799888 52 Q99623,P30536,Q13190,P42858,Q16543,P52789,Q96HY6,P21796,P33176,P27544,P04062,P12235,Q14457 13 +Antigen processing and presentation of exogenous peptide antigen via mhc class i 0.7484636402192943 1.5560661612113644 0.1196923605771291 1.0 0.3190175751856708 4 Q9UIQ6,Q03518 2 +Meiotic spindle assembly 0.7310948905109301 1.5535675054835123 0.1202876153364516 1.0 0.3202156700966365 5 O14965,O95067,O14777,Q12768 4 +Regulation of membrane permeability 0.492791041080534 1.5535647633951797 0.1202882698549541 1.0 0.3202156700966365 20 P12235,P42345,Q9Y5Z4,P45880 4 +Er overload response 0.7477847366609626 1.553110642960714 0.1203967038976219 1.0 0.3203743596821553 4 Q96A33,O76024 2 +Lipid modification 0.3648723368599264 1.55167569874117 0.1207398401981643 1.0 0.3209283546725099 56 Q2T9J0,P23786,Q10713,O14678,P52429,P16435,O14975,Q709F0,O14734,Q9BWD1,P28288,Q16134,A1L0T0,Q96N66,P35610,O15254,P04062,Q15067 18 +Maternal process involved in female pregnancy 0.623151257587747 1.5509833817507666 0.1209056665111991 1.0 0.3210776947173164 9 Q9BQE5,O60684,Q96EP5,P35613,O75592 5 +Collagen fibril organization 0.5989925306595313 1.5481617162151482 0.121583366147149 1.0 0.3223555752151887 11 O75718,P13674,Q92791,Q96AY3 4 +Regulation of lipid biosynthetic process 0.4503622980510193 1.5463608025199147 0.1220174551361776 1.0 0.3227241195500193 27 P30536,O75874,P42345,P05023,P16435,Q8WTV0,P04083,Q8NF37,Q13510,O75477 10 +Regulation of endothelial cell migration 0.4279093605606312 1.5392407688270322 0.1237455280901345 1.0 0.3263738566428708 30 Q9H6U6,O94813,O14786,Q8WTV0,P06576,P61586,P57105,P42785,P04083,P09601 10 +Neuron projection arborization 0.6718420398907304 1.5388773761905632 0.1238342352967798 1.0 0.3264506005548558 7 Q9HCE1,Q13641 2 +Negative regulation of ion transmembrane transport 0.5353327404147462 1.5377448287822957 0.124111018050105 1.0 0.3267225079097872 16 P21796,Q06787,P46934 3 +Vacuolar transport 0.3639928559005565 1.537167068295745 0.124252402485038 1.0 0.3267912886199677 55 P07602,P46934,Q96L92,P13473,Q9NZJ7,O15118,Q14108,Q14457 8 +Meiotic sister chromatid cohesion centromeric 0.6755179457251144 1.534538526437706 0.1248972227866165 1.0 0.3278223248499176 3 O43683,P30153 2 +Kidney morphogenesis 0.7267695985372431 1.5341444247399196 0.1249941262990694 1.0 0.3278223248499176 5 O75844 1 +Regulation of phospholipase activity 0.6198060658737905 1.532828478463745 0.1253181218175127 1.0 0.328540757237922 9 P04083,P50897 2 +Regulation of ph 0.4845935142863929 1.5306219601548614 0.1258628511170065 1.0 0.3290703942371346 21 O75503,Q9Y487,P50897,Q8N511,Q93050 5 +Regulation of cellular ph 0.4845935142863929 1.5306219601548614 0.1258628511170065 1.0 0.3290703942371346 21 O75503,Q9Y487,P50897,Q8N511,Q93050 5 +Leukocyte differentiation 0.3460039403583097 1.5279337075988058 0.1265289981110429 1.0 0.3301443361017915 71 P42345,P24390,Q15904,O15360,O96005,P05067,P61586,Q5HYI8,Q13315,P01889,P04083,Q14739,P04062 13 +Inorganic ion import across plasma membrane 0.6696243029073498 1.5279154682273293 0.1265335271709853 1.0 0.3301443361017915 7 P55011,Q9BXP2,P05023,Q15043 4 +Negative regulation of cell cycle g2 m phase transition 0.4480924835875406 1.5270386281087012 0.1267514062650618 1.0 0.3305813703940127 27 Q92547,Q6NUQ1,Q96GD4,Q9Y619,Q13315,P53350,Q96JB5,Q96K76 8 +Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation 0.6070595099183154 1.5248987388664723 0.1272843564936576 1.0 0.3314444235362625 2 Q15363 1 +Regulation of translation initiation in response to endoplasmic reticulum stress 0.6070595099183154 1.5248987388664723 0.1272843564936576 1.0 0.3314444235362625 2 Q15363 1 +Antigen processing and presentation of exogenous peptide antigen 0.7240722626435525 1.5220222498423648 0.1280035057352155 1.0 0.3325253383351087 5 Q9UIQ6,Q03518 2 +Nuclear pore complex assembly 0.6176456042927392 1.521094321259224 0.1282361693410054 1.0 0.3328661958922776 9 Q9BTX1,Q8N1F7,Q9NQC3 3 +Fucose metabolic process 0.6723081412313654 1.5192572138700011 0.1286977649451599 1.0 0.3339322789917515 3 Q9BTY2,P04066 2 +Regulation of cell cycle g2 m phase transition 0.3648254098416381 1.5181464038559411 0.1289774952362861 1.0 0.3345258196602804 45 Q92547,Q5TBB1,Q96GD4,Q7L7X3,Q6NUQ1,O14965,Q9Y619,P05067,Q13315,Q96QE3,P53350,Q96JB5,Q96K76 13 +Negative regulation of ion transport 0.4879212272407676 1.5174701496977523 0.129148024457713 1.0 0.3345514400286368 20 P21796,Q06787,P46934 3 +Regulation of cholesterol biosynthetic process 0.7394276048570222 1.5166928303755185 0.1293442553112849 1.0 0.3345514400286368 4 O75477,P16435 2 +Regulation of alcohol biosynthetic process 0.7394276048570222 1.5166928303755185 0.1293442553112849 1.0 0.3345514400286368 4 O75477,P16435 2 +Signal peptide processing 0.7224141077331457 1.5145667668819147 0.1298821535915548 1.0 0.3355433399242551 5 O75503,P67812 2 +Peptidyl proline modification 0.4163650578116967 1.5099741833639817 0.1310500118314292 1.0 0.3366943730366483 32 Q32P28,Q96AY3,Q9NWM8,O95302,Q9Y680,O75718,P13674 7 +Positive regulation of membrane permeability 0.5556381353319038 1.5097926901570569 0.1310963308608101 1.0 0.3366943730366483 14 P45880 1 +Vascular transport 0.5798855076904561 1.5088758782134424 0.1313305052462636 1.0 0.3370119364331522 12 P08183,P55011,P11166,P53985,P30825,P23634 6 +Negative regulation of steroid metabolic process 0.6701104197319762 1.5087879052508095 0.1313529925603871 1.0 0.3370119364331522 3 O75477 1 +Regulation of cysteine type endopeptidase activity 0.3630403303541671 1.5087055263978406 0.1313740526357822 1.0 0.3370119364331522 52 Q96A26,Q15418,O14737,P16435,P61586,Q9NZJ7,Q9BXK5,Q15392,Q9P0J0,Q96K76 10 +Modification of postsynaptic structure 0.6654479297922665 1.5072562945802903 0.1317449756230893 1.0 0.3372445537466234 7 Q9UQB8,P61586 2 +Cellular transition metal ion homeostasis 0.486469031250384 1.5066930093083113 0.1318893642645258 1.0 0.3372445537466234 20 Q8N511,P09601,Q9Y487,Q15043 4 +Positive regulation of dna catabolic process 0.6695028345475642 1.5058926615071524 0.1320947307286002 1.0 0.3372445537466234 3 Q13315 1 +Glycoside metabolic process 0.614343725977024 1.503147686445809 0.1328009641696548 1.0 0.3372445537466234 9 Q9BTY2,P06280,Q9NUJ1,P04062 4 +Hypothalamus development 0.7019162276175515 1.4988684073886076 0.1339077736957734 1.0 0.3395925976475971 6 O14786,P27695,O14949,O75569 4 +Membrane protein proteolysis 0.5894360806101805 1.4933921847014238 0.1353345575181612 1.0 0.3413570560456702 11 Q8TCT9,Q9NZ08,Q92542,P38159 4 +Positive regulation of glucose import 0.6668320889511349 1.493161701834184 0.1353948644568408 1.0 0.3413570560456702 3 Q16625 1 +Adipose tissue development 0.5889569448436568 1.4906423285106891 0.1360554248983674 1.0 0.342592363078698 11 O15173,P35610,P43490 3 +Regulation of mitochondrial membrane permeability 0.5152826250374121 1.4890670632891052 0.1364697099211422 1.0 0.3427557708813873 17 Q9Y5Z4,P45880 2 +Positive regulation of chemokine c x c motif ligand 2 production 0.6000583430571862 1.4881785986732012 0.1367037996604514 1.0 0.3427557708813873 2 P14174 1 +Chemokine c x c motif ligand 2 production 0.6000583430571862 1.4881785986732012 0.1367037996604514 1.0 0.3427557708813873 2 P14174 1 +Positive regulation of dendritic cell differentiation 0.600058343057185 1.4881785986731946 0.1367037996604532 1.0 0.3427557708813873 2 P17931 1 +Cellular response to vitamin d 0.7327288119992448 1.4874562656249055 0.1368943458512002 1.0 0.3428628616318991 4 P20020 1 +Regulation of reactive oxygen species metabolic process 0.407432562901157 1.485860257016118 0.1373160877677492 1.0 0.3436568146193633 34 P30536,P00374,P61586,P42785,P00403,Q9BSK2,Q14457 7 +Intermembrane lipid transfer 0.6217716929227006 1.484282493341735 0.1377339927139118 1.0 0.3443087467385484 8 P30536,Q14849,P22059,Q9BZF1 4 +Endoplasmic reticulum to golgi vesicle mediated transport 0.3540274693303048 1.4827250488457109 0.1381474766490347 1.0 0.3452108689150669 65 Q13190,Q96PC5,P51572,Q9P2W9,Q6NUQ1,O43731,P24390,Q9Y282,Q9HD47,O95249,Q12907,P49257,O95487,Q9Y3B3,Q9HCU5,Q8NHH9,Q8IUR0 17 +Positive regulation of peptidase activity 0.3769065500581701 1.4766167215475137 0.1397784068106091 1.0 0.347961269154483 41 Q96A26,O14737,P05067,P61586,Q9BXK5,Q9NZJ7,Q96HY6,O76031,Q9P0J0 9 +Response to xenobiotic stimulus 0.3245704364483246 1.4758721910086103 0.1399782061775762 1.0 0.3481944613105593 79 P30536,P08183,O15217,P16435,P54646,P07099,O43169,O15118,Q06520,P61586,Q13535,O15228,P09601,Q14457,Q96K76 15 +Forebrain cell migration 0.5739804731386244 1.4740140299277324 0.1404778137016649 1.0 0.3493048175484369 12 Q96N66,P61586,Q9NQC3 3 +Ventricular cardiac muscle cell action potential 0.6586668593924639 1.4736705188473218 0.1405703242335965 1.0 0.3494024498563864 7 Q96PU5 1 +Ether biosynthetic process 0.7132196897538386 1.4731805370319209 0.140702361677047 1.0 0.3494658960351184 5 Q6IAN0,O15228,Q8WVX9 3 +Neuroblast division 0.6623869273417031 1.471957123540981 0.141032456321404 1.0 0.350020793638825 3 Q96N67,Q92974 2 +Asymmetric neuroblast division 0.6623869273417031 1.471957123540981 0.141032456321404 1.0 0.350020793638825 3 Q96N67,Q92974 2 +Positive regulation of dephosphorylation 0.5249934710271886 1.4692646049142353 0.1417610332135082 1.0 0.3515404446165832 16 Q14738,P04062,Q86XL3 3 +Positive regulation of nucleotide metabolic process 0.6955126137891302 1.469100694005816 0.1418054795641719 1.0 0.3515404446165832 6 P54646,P00403 2 +Adiponectin activated signaling pathway 0.5959743290548511 1.4667320166283695 0.1424489697102919 1.0 0.3526028439226465 2 P33121 1 +Regulation of wnt signaling pathway 0.3602788120947195 1.4651828218894285 0.142871045011234 1.0 0.3533810016448239 45 Q96K76,Q13641,P05067,Q9H2V7,P48729,P50402,P52294,Q6DKJ4,Q5T9L3 9 +Positive regulation of atp metabolic process 0.6561832131146832 1.4613572073415495 0.1439174378896348 1.0 0.3552122659150692 7 P54646,P00403 2 +Negative regulation of axon extension 0.6599915014406303 1.460522821748131 0.1441464400540151 1.0 0.3553815473537236 3 Q9NQC3 1 +Acute inflammatory response 0.7103940161139275 1.4604469472188029 0.1441672781249028 1.0 0.3553815473537236 5 Q9BQE5,Q4KMQ2 2 +Nls bearing protein import into nucleus 0.6051945529643866 1.4533427055529735 0.1461286256773881 1.0 0.3585494006907765 9 P49792,Q7Z3B4,P52294,O60684 4 +Sterol homeostasis 0.5703988830113053 1.4528426506366954 0.1462674469668106 1.0 0.3586722671884197 12 P61916,Q5BJF2,Q8WTV0,O15118,Q9UKM9,P35610 6 +Endoplasmic reticulum tubular network organization 0.5813807567758107 1.4471166232045836 0.1478642630156683 1.0 0.3605668130467542 11 Q8NHH9,O95197,P57088,Q9NQC3 4 +Regulation of tor signaling 0.4780416923239106 1.444037599262309 0.1487283992279009 1.0 0.3609065412603783 20 O75844,P04062 2 +Regulation of steroid metabolic process 0.545116962592115 1.443988122578214 0.1487423164017531 1.0 0.3609065412603783 14 P30536,P05023,P16435,Q9UBM7,Q13510,O75477,Q9UHI6 7 +Xenobiotic metabolic process 0.5211689096281262 1.4438770113352224 0.1487735742318383 1.0 0.3609065412603783 16 Q06520,O15217,P07099,O43169 4 +Phosphatidylinositol 3 phosphate biosynthetic process 0.6893675741437446 1.4405009743439898 0.1497257145599864 1.0 0.362813936094029 6 Q14457 1 +Polyol biosynthetic process 0.5682774235618916 1.4402935525285887 0.149784364760062 1.0 0.3628220751404678 12 O15269,Q13510,P00374,P04062 4 +Positive regulation of synaptic transmission 0.507764446501688 1.437605586046055 0.1505459950624188 1.0 0.364129310578545 17 Q92542,P27695,P33176,Q13277,Q06787,P05067,Q14168 7 +Peptide catabolic process 0.5793548350615011 1.4354642705615832 0.1511548427792477 1.0 0.3653282853011295 11 O14773,P42892,Q9UIQ6,Q6P179,Q9NZ08 5 +Amino acid import across plasma membrane 0.688245435137131 1.4352751001011377 0.1512087203410343 1.0 0.3653282853011295 6 P30825,Q15041 2 +Biomineralization 0.5548813431131626 1.4337709399138296 0.1516376404202213 1.0 0.3661087206099326 13 O75844,P20020,Q4KMQ2,Q8N5W9,Q6P4Q7 5 +Regulation of natural killer cell mediated immunity 0.6502836799479423 1.43208494902409 0.152119511331934 1.0 0.3667186750037293 7 P01889,P46108,P04439 3 +Negative regulation of transmembrane transport 0.4758484988403034 1.4277021735193456 0.1533776003101885 1.0 0.3683524225732668 20 P21796,Q06787,P46934 3 +Synaptonemal complex organization 0.6865502127006988 1.4273785146544111 0.153470820377219 1.0 0.3683524225732668 6 P46379,Q92791 2 +Protein targeting to vacuole 0.4930586776607834 1.4241785312769315 0.1543947979357034 1.0 0.369669383387798 18 Q96RL7,P46934,P13473,Q99523,Q14108 5 +Positive regulation of endocytosis 0.4597571713065858 1.4217587669627774 0.1550962933992687 1.0 0.3705622120515881 23 Q4KMQ2,Q96PU5,P50897,Q06787 4 +Glycosyl compound metabolic process 0.4221956471007493 1.4214633436851392 0.1551821028219695 1.0 0.3705622120515881 29 P49902,O60725,Q9BTY2,Q13126,P06280,Q9NUJ1,P04062 7 +Outer mitochondrial membrane organization 0.7005935894664523 1.4162356273911334 0.1567065279859714 1.0 0.3737943426550143 5 O14737,Q9NS69 2 +Cellular homeostasis 0.3042865487818557 1.415428959294316 0.1569427637807279 1.0 0.3740929130126671 150 P20020,P52789,Q15120,P16615,O95202,P50897,Q15907,Q8N511,Q9Y6M7,Q9HD20,Q4KMQ2,P14625,Q9Y487,P10253,P09601,P22059,Q15043,P42858,P55011,P62995,P54646,P05067,Q96PU5,Q9BXP2,Q8IYU8,Q93050,O76024,P05023,Q9NQC3,Q16891,Q15904,O75503,P13473,Q92544,Q96A33,Q8N5M9,Q9NUT2 37 +Dicarboxylic acid metabolic process 0.3558335790629216 1.4150698042870171 0.1570480305004247 1.0 0.3742008627973082 44 Q9H2D1,O75874,P48735 3 +Membrane depolarization 0.5287984154715648 1.4147844343760787 0.1571317092908999 1.0 0.3742060822402518 15 Q9HD47,P30536 2 +Iron ion homeostasis 0.4917166422488966 1.4146734117662731 0.1571642734919436 1.0 0.3742060822402518 18 Q8N511,P09601,P30519,Q9Y487 4 +Positive regulation of wound healing 0.6466794007404819 1.414186073155575 0.1573072759886691 1.0 0.3743329343771751 7 Q16625,Q4KMQ2,P04083 3 +Autophagosome organization 0.4281805104318012 1.4134899310491789 0.1575117198732463 1.0 0.3744898209450153 28 Q8TBX8,Q96GC9,P04062,P16615 4 +Positive regulation of cell killing 0.6463872386073178 1.412734725748309 0.1577337371226068 1.0 0.3747860799837763 7 P01889,P04439,Q9NUQ9 3 +T cell homeostasis 0.6833954400500917 1.4126775458256926 0.1577505566771091 1.0 0.3747860799837763 6 P42574,O95067,P49327,P62753 4 +Regulation of leukocyte mediated immunity 0.3997897415998199 1.411309159773288 0.1581534747995294 1.0 0.3753089045993749 34 Q9H2U1,Q96QE3,P01889,P46108,O96028,P04439,Q9NUQ9,Q96FV9,Q96FZ2,P09601 10 +Regulation of gliogenesis 0.5398781517629702 1.4111533736984443 0.1581993950200961 1.0 0.3753089045993749 14 P42345,Q96G23,P30536 3 +Sodium ion homeostasis 0.6824428406859699 1.4082371486279377 0.1590608595712761 1.0 0.3766174205605469 6 Q96PU5,P55011,P05023 3 +Protein o linked glycosylation via serine 0.7141462706615426 1.4061750423784882 0.1596721532608653 1.0 0.3772277864510281 4 Q8N4A0,Q10472 2 +Regulation of axon guidance 0.7136602451838805 1.4040461456145743 0.1603051087573594 1.0 0.378301202481138 4 O14786,O75592,O94813 3 +Glomerular basement membrane development 0.5840140023337339 1.4038288020296048 0.1603698350745706 1.0 0.378301202481138 2 P11047 1 +Post embryonic animal organ development 0.5840140023337237 1.403828802029551 0.1603698350745865 1.0 0.378301202481138 2 Q07812 1 +Oocyte differentiation 0.5499061922627235 1.4034317774905187 0.1604881225327918 1.0 0.3784128853971183 13 Q8N2A8,Q12768,O14965,Q9H6S0,Q9Y2W6,Q13315,P30153 7 +Regulation of regulated secretory pathway 0.4770734752204972 1.4030039991791872 0.1606156463987269 1.0 0.378476624268859 19 O00186,O14936,P05771,P11279,Q06787,P16615,Q4J6C6,P09601,P51809 9 +Regulation of release of cytochrome c from mitochondria 0.5737071192099776 1.402954160094327 0.1606305087761006 1.0 0.378476624268859 11 Q96A26,O14737 2 +Sensory perception of light stimulus 0.4769364390550684 1.4019996000654598 0.1609153661225133 1.0 0.3787398251420131 19 Q99797,O76024,P50897,O75569,O60313 5 +Positive regulation of protein dephosphorylation 0.5264727867188054 1.3997713594374863 0.1615817969701685 1.0 0.3794916792119705 15 Q86XL3,P04062,Q14738 3 +Tail anchored membrane protein insertion into er membrane 0.595316922361276 1.3994620008893248 0.1616744856343155 1.0 0.3795735151099744 9 P46379,Q9NPA0,O43681 3 +Adult behavior 0.4618881326755901 1.3968214753643236 0.1624672626597865 1.0 0.380346121146457 22 O75844,P50897,O15118 3 +Regulation of tube size 0.5486570200886172 1.3958090327221868 0.1627720095887914 1.0 0.3808314800882786 13 Q9HB40,O60568,P61586,P42892 4 +Endocrine process 0.7117658652268983 1.3957471227046578 0.1627906585869585 1.0 0.3808314800882786 4 P42892 1 +Cd40 signaling pathway 0.6949991225649998 1.3909694701439088 0.164234684811634 1.0 0.3832532011856126 5 O15360 1 +Neutral amino acid transport 0.7103168814939201 1.3893980473834306 0.1647117437322613 1.0 0.3839573879087393 4 Q9H9B4,Q96NB2 2 +Response to manganese ion 0.6946511331406577 1.3893972528213872 0.1647119852122982 1.0 0.3839573879087393 5 P30536 1 +Calcium ion transmembrane transport 0.3587979733990756 1.3883607557050357 0.1650272202129414 1.0 0.3842074724151567 43 P20020,Q4KMQ2,P21796,Q06787,P16615,O95202,Q8IYU8,Q96GC9 8 +Negative regulation of receptor signaling pathway via jak stat 0.6445871024219398 1.3868841906759286 0.1654770793074127 1.0 0.3843754316514132 3 O14964,P30153 2 +Negative regulation of receptor signaling pathway via stat 0.6445871024219398 1.3868841906759286 0.1654770793074127 1.0 0.3843754316514132 3 O14964,P30153 2 +Erad pathway 0.3734720996515484 1.3864767623923722 0.165601371129878 1.0 0.3845280245414931 40 P46379,Q8TCT9,P51572,O76024,Q5VYK3,Q9UBV2,Q9UBU6,Q9BUN8,P14625,Q8TCJ2,Q6NTF9,Q96A33,Q13438,O75477 14 +Folic acid containing compound metabolic process 0.5351881557960089 1.3817252459237432 0.167056079630858 1.0 0.3872207681164571 14 P34896,Q9H2D1,P00374,Q92820 4 +Reproductive system development 0.3463356250544065 1.3813404017494448 0.1671743213139418 1.0 0.3873580142874598 65 O75874,P07602,Q9NZJ7,Q13315,P35613,P04083,Q15392,Q8TAF3,O95470,P49321 10 +Endoplasmic reticulum unfolded protein response 0.4597536795957094 1.3803012794152267 0.1674939012129481 1.0 0.3879474779937815 22 P57088,O76024,Q9BUN8,Q96JB5,Q6NTF9,Q9Y4P3,Q96HY6 7 +Negative regulation of nervous system development 0.4863682003461889 1.376758700227935 0.1685868634923983 1.0 0.3897940886519495 18 Q15154,P30536,Q9NQC3,O14786,Q9Y4G8,Q96G23 6 +Mrna transport 0.3247416897962323 1.376409763958581 0.1686948067691727 1.0 0.3897940886519495 76 Q8TD16,P41208,Q96FV9,Q12769,P51991,Q7Z3B4,Q99567,Q06787,Q8NFH4,Q92945,Q08211,Q96MU7,Q9ULX6,Q5SRE5,Q9BTX1,P22626,Q8N1F7 17 +Mitotic g2 m transition checkpoint 0.4641770352943479 1.37593640664925 0.1688413225277134 1.0 0.3897940886519495 21 Q13315,Q96JB5,Q6NUQ1,Q9Y619 4 +Amyloid precursor protein biosynthetic process 0.6751964824976129 1.374440571101312 0.1693049480976491 1.0 0.39045921865795 6 Q9NQX7,Q9Y287,P35610 3 +Response to lipid 0.3016053146057472 1.3729539071417394 0.1697666763926808 1.0 0.3910175256190845 152 P30536,O75874,P20020,Q15120,Q8TB36,Q86UE4,Q13315,Q14103,P04083,Q9P0J0,P04062,O95831,Q8WTV0,P16278,O15228,P49321,P61586,Q9H7B4,P08670,O15173,P46934,P16435,O15118,Q13126,Q96HY6 25 +Regulation of autophagy of mitochondrion 0.5218816492498287 1.3701107216024315 0.1706523414772633 1.0 0.3929195314995797 15 P42858,P30536,P21796,P27544,Q9UBN7,P12235 6 +Divalent inorganic cation homeostasis 0.3508355435693543 1.3689916217247078 0.1710018938663586 1.0 0.3935862601020854 54 P20020,P42858,Q9HD20,O76024,P14625,P05067,P16615,Q8NE01,O95202,Q96A33,Q8IYU8,Q15043 12 +Activin receptor signaling pathway 0.5773045507584718 1.368491353449773 0.1711583266673206 1.0 0.3936701505751694 2 P67870 1 +Regulation of activin receptor signaling pathway 0.5773045507584718 1.368491353449773 0.1711583266673206 1.0 0.3936701505751694 2 P67870 1 +Peptidyl proline hydroxylation to 4 hydroxy l proline 0.6889750043264182 1.3637436539585694 0.172648259629438 1.0 0.3958483157541483 5 P13674 1 +Cellular response to corticosteroid stimulus 0.5549886337125368 1.3615573479894427 0.1733376235034376 1.0 0.3972322124262751 12 P20020,Q9H7B4,P04083,O95831 4 +Interleukin 23 production 0.575845974329067 1.360805600897446 0.1735751314584734 1.0 0.3973709575779243 2 P63000 1 +Antifungal innate immune response 0.5758459743290586 1.3608056008974012 0.1735751314584876 1.0 0.3973709575779243 2 Q9Y4E8 1 +Cleavage furrow formation 0.6388731283197405 1.359531093153773 0.1739783565873482 1.0 0.3977108754119934 3 P61586 1 +Cellular response to reactive nitrogen species 0.5981918642362891 1.3588696156994244 0.1741879085544146 1.0 0.3977108754119934 8 Q99707,Q14103,O95831 3 +Response to nitric oxide 0.5981918642362891 1.3588696156994244 0.1741879085544146 1.0 0.3977108754119934 8 Q99707,Q14103,O95831 3 +Embryonic axis specification 0.6716983479365772 1.358114934535404 0.1744272170263765 1.0 0.3981187471746374 6 Q9Y2W6,Q8N2A8,Q9UK61 3 +Insulin receptor signaling pathway 0.4214146691568111 1.3541606057846438 0.1756851441589506 1.0 0.4004068228740504 28 Q15043,Q9UQB8,P43490 3 +Cellular process involved in reproduction in multicellular organism 0.3480138643075957 1.3540049967235814 0.1757347835838563 1.0 0.4004068228740504 59 P62753,O14965,Q13315,O14777,Q96MU7,P30153,Q8N2A8,Q12768,Q96GX5,Q01085,Q9Y2W6,Q8NB78,A0AVF1,O15360,Q9H6S0,O95067,P42345,P78310,O94813,P53350,Q9UHI6 21 +Phospholipid catabolic process 0.5304070056359255 1.3516972235192348 0.1764721936424238 1.0 0.4015293116094262 14 Q8WTV0,O75874,Q8NCC3,Q8NHP8 4 +N terminal peptidyl methionine acetylation 0.636256589462574 1.3470004511758158 0.1779800873730241 1.0 0.4040868413620042 3 Q9BXJ9 1 +Isoleucine metabolic process 0.6691975864052293 1.3464404081814816 0.1781605266411556 1.0 0.4042494383884037 6 A1L0T0 1 +Striated muscle adaptation 0.6999646507256104 1.344009504142132 0.1789453135719219 1.0 0.4054693189430081 4 P16615 1 +Regulation of system process 0.3383330530581404 1.343756213733243 0.1790272328846656 1.0 0.405514912733578 68 O75844,P42892,Q9HD47,Q06787,P05067,P61586,P16615,Q9UQB8,P10253,P04062,Q14457 11 +External encapsulating structure organization 0.4061647511777382 1.33981328401304 0.1803060557782887 1.0 0.4072868633449675 30 Q96AY3,Q53GQ0,P05067,O75718,P13674,Q92791 6 +Intermediate filament organization 0.594382483356644 1.338565381495492 0.1807122023462539 1.0 0.4076429947735024 8 P07197,P08670 2 +Glycerol ether metabolic process 0.6670904084526081 1.3366012204288604 0.1813528404557605 1.0 0.4082460854444941 6 Q6IAN0,O15228,Q8WVX9 3 +Negative regulation of cell development 0.4488201893438185 1.3354455100805471 0.181730578114011 1.0 0.4089561226283061 23 P30536,Q9UBS4,Q15154,Q9NQC3,O14786,Q8N5W9,Q9Y4G8,Q96G23 8 +Regulation of ossification 0.5831778798044559 1.3331248455994025 0.1824908371351405 1.0 0.4102467448752024 9 O75844,P20020,Q4KMQ2 3 +Regulation of endoplasmic reticulum unfolded protein response 0.5932291542915551 1.332416414084365 0.1827233913267951 1.0 0.4104750065150869 8 O94874,Q96HY6,P57088,O76024 4 +Carbohydrate derivative metabolic process 0.2775152061071592 1.3321614605223526 0.1828071377248972 1.0 0.4104750065150869 272 Q7LGA3,Q8WVC6,Q15120,Q53GQ0,P24539,Q06520,P06865,O60512,P06280,O60502,P50897,Q96K12,P08236,P00403,P04062,Q2TAA5,P49902,P16278,Q8N4A0,O75964,Q9BRR6,Q9H773,Q8TB61,Q14168,Q9Y287,O60725,P17900,O43292,Q9BTY2,Q15118,P54646,P05067,P15586,Q9UL01,P61586,Q99519,Q96L58,P54802,Q9NPH0,Q9NUJ1,Q8NBX0,A8MXV4,Q9NQX7,O60476,Q6ZXV5,O15118,P04844,Q13126,Q8NAT1,O60313,P35610,O60568 52 +O glycan processing 0.681967016436358 1.3320510675383852 0.1828434081139285 1.0 0.4104750065150869 5 O43505,Q8N4A0,Q10472 3 +Inflammatory cell apoptotic process 0.6965686249924015 1.3291112416931088 0.1838112719794229 1.0 0.4123570583808908 4 O75844 1 +Regulation of circadian rhythm 0.418315735701428 1.3269450800261904 0.1845268505906361 1.0 0.4132645711862642 28 P42345,P23246,P54646,Q9UNS1,Q14103,Q9Y5V3,Q9BWF3 7 +Cellular response to increased oxygen levels 0.5921076782171667 1.3264366099678664 0.1846951190519248 1.0 0.4132747849689008 8 Q8N511,Q9Y487 2 +Antigen processing and presentation of exogenous antigen 0.5920291925151452 1.3260180943584583 0.1848337039812451 1.0 0.4132747849689008 8 Q9UIQ6,Q03518 2 +Atp metabolic process 0.3093455352755075 1.3258672787755206 0.1848836630691912 1.0 0.4132747849689008 109 P30536,P51970,P24539,O43676,O14949,P00403,P08574,O75964,Q9BRR6,Q9BSK2,P14406,Q9Y6M9,P03886,Q9UDW1,P54646,P05067,P61586,P13073,Q9NTK5,O76031 20 +Iron ion transport 0.5818367893944962 1.3257899248290428 0.1849092911716996 1.0 0.4132747849689008 9 O15173,Q15043 2 +Intracellular protein transmembrane transport 0.4572532467003065 1.323265375739474 0.1857471418084886 1.0 0.4138786908479804 21 O14925,Q99595,O60830,Q15629,Q9UGP8,O95831 6 +Central nervous system projection neuron axonogenesis 0.6310541365129946 1.3220782916582798 0.1861420816797552 1.0 0.4144301981103095 3 O94813 1 +Glycerophospholipid metabolic process 0.3438454296868327 1.3207259067280988 0.1865927726425864 1.0 0.4151166765423291 63 Q99623,Q9NP80,Q13315,Q14457,Q10713,Q8WTV0,O15228,Q96N66,Q6IAN0,O43292,Q9BZF1,Q9BTU6,Q9NXE4,Q8NCC3,Q9NPH0,Q9UG56,P52429,O60762,P48651,Q9NUQ2,Q8TBX8,Q8NF37,Q9H490 23 +Regulation of synaptic transmission gabaergic 0.6301419416000698 1.3177076092888256 0.1876015463192888 1.0 0.4163142870974546 3 P33176 1 +Regulation of plasma lipoprotein particle levels 0.5246642712909466 1.3155990455155633 0.1883086541051302 1.0 0.4173381529129996 14 Q8WTV0,P61978,P35610,P09601 4 +3 utr mediated mrna destabilization 0.6625726074591851 1.3155005154029005 0.1883417442416948 1.0 0.4173381529129996 6 Q9HCE1,Q14103,Q92945 3 +Membrane depolarization during action potential 0.6934599389500506 1.3154707565938042 0.1883517392181306 1.0 0.4173381529129996 4 Q9HD47 1 +Regulation of post translational protein modification 0.693428197137894 1.315331466175584 0.1883985273556618 1.0 0.4173381529129996 4 Q32P28 1 +Phagosome lysosome fusion 0.5670945157526381 1.3146707894538323 0.1886205677503225 1.0 0.4173381529129996 2 P51149 1 +Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii 0.5670945157526348 1.3146707894538137 0.1886205677503287 1.0 0.4173381529129996 2 P50570 1 +Neuron recognition 0.6263968427856235 1.3132981516260798 0.1890825011385102 1.0 0.4173725403627756 7 P35613,P05067,Q9NQC3 3 +Regulation of long term synaptic potentiation 0.6927770118095493 1.3124738670256066 0.189360297877152 1.0 0.4173725403627756 4 P05067 1 +Negative regulation of map kinase activity 0.5887619073257068 1.3085932311258324 0.1906721750105857 1.0 0.4193835504023653 8 P04062 1 +Negative regulation of neuron apoptotic process 0.409615842503008 1.3084809620204672 0.1907102277355468 1.0 0.4193835504023653 29 O76024,O14786,P61586,P50897,P09601,P04062 6 +Calcium ion regulated exocytosis 0.5679307154120373 1.3069630951068445 0.1912252455779246 1.0 0.4203752299773338 10 Q9BRK5 1 +Glycerophospholipid catabolic process 0.5883566423827515 1.3064315939388067 0.1914058275973831 1.0 0.4206312929316905 8 Q8WTV0,Q8NCC3 2 +Dna modification 0.4023578616942673 1.3047372895707368 0.1919823192715726 1.0 0.4213337722608894 30 O75844,Q9Y2W6,Q8N2A8 3 +Transport of virus 0.6601948889233431 1.3043927535766762 0.1920997046400661 1.0 0.421450423971808 6 O60684 1 +Modulation of excitatory postsynaptic potential 0.6757707139577657 1.3040159334981594 0.1922281497939075 1.0 0.421450423971808 5 Q9UQB8 1 +G quadruplex dna unwinding 0.6907167968719389 1.3034324717161632 0.1924271566368474 1.0 0.4217458256015339 4 Q9H2U1,P22626 2 +Response to vitamin d 0.6755762934085248 1.3031361308678764 0.1925282903942327 1.0 0.4217479023460991 5 P20020 1 +Regulation of mrna catabolic process 0.3082695606760525 1.3001229044422946 0.1935588486138737 1.0 0.4228941545052881 81 Q14011,P67809,P11940,Q14103,P98175,Q99729,Q13151,P07910,O60506,Q9H2U1,Q06787,Q92945,P08670,P51114,Q92804,Q00839,P51116,Q9HCE1,Q969T7,P35637,Q08211 21 +Regulation of neural precursor cell proliferation 0.5109952387298914 1.2996821365964102 0.1937099352893305 1.0 0.4228941545052881 15 Q8NEM2,P61586,P55209 3 +Response to wounding 0.3088593671882279 1.2996722764920787 0.1937133161319584 1.0 0.4228941545052881 85 P30536,P42345,Q4KMQ2,P52429,P38435,Q8WTV0,P00374,P61586,P42785,P04083,Q99707,Q16625,P09601,Q96G23 14 +Multi multicellular organism process 0.4211941797296401 1.296736368833441 0.1947219111797253 1.0 0.42450670470477 27 Q9BQE5,O60684,Q9UIQ6,Q96GC9 4 +Regulation of monooxygenase activity 0.56607066674735 1.2965134877555613 0.1947986362788607 1.0 0.424524416022038 10 Q8WTV0,P06280,P00374,P16435 4 +Positive regulation of endoplasmic reticulum unfolded protein response 0.6253158312963432 1.2945808360237163 0.195464866855513 1.0 0.4253475395250313 3 P57088 1 +Positive regulation of ire1 mediated unfolded protein response 0.6253158312963432 1.2945808360237163 0.195464866855513 1.0 0.4253475395250313 3 P57088 1 +Myelin assembly 0.6579688604542436 1.2939924249411634 0.1956680373579082 1.0 0.425438588847778 6 Q9NR77 1 +T cell mediated cytotoxicity 0.6578112103659602 1.2932558232785452 0.1959225942196896 1.0 0.4258509649783383 6 P01889,P04439 2 +Regulation of catabolic process 0.257829638159684 1.2914529529079282 0.1965466589703242 1.0 0.4266102558606445 330 P46379,P30536,O75874,Q86UE4,P21796,O00560,P67809,P11940,Q13315,Q9NZ45,Q14103,P98175,Q9P0J0,P04062,O75844,Q14457,O15269,O95831,P07602,Q8WTV0,Q99729,O15270,Q13151,Q9Y487,P09601,Q14108,O60506,Q2T9J0,P54646,Q06787,P05067,Q9NZJ7,Q16850,Q96PU5,P51114,P08670,P12235,Q93050,Q92804,P42345,P10619,P51116,P46934,Q6ZXV5,Q969T7,P35637,Q9HCE1,P48729,O15118,Q8TBX8,Q96JB5,Q96HY6 52 +Regulation of nucleotide metabolic process 0.4618611210393772 1.2913077488868958 0.1965969847184683 1.0 0.4266102558606445 19 P05067,Q15118,P54646,P00403 4 +Regulation of gene silencing by rna 0.4615004814027614 1.2886558374374415 0.1975177620963806 1.0 0.4275941078576744 19 O75844,Q9HAV4,Q06787,Q01085,P51114 5 +Regulation of establishment of planar polarity 0.6723423708976446 1.2885008430887266 0.1975716755599617 1.0 0.4275941078576744 5 Q8TAA9,P61586 2 +Positive regulation of viral life cycle 0.6208026608630126 1.285439251050794 0.1986388324576595 1.0 0.429195923143616 7 O60684 1 +Sulfur amino acid biosynthetic process 0.6554318887232727 1.2821382250266908 0.1997941618785548 1.0 0.430142836353468 6 Q13126 1 +Methionine biosynthetic process 0.6554318887232727 1.2821382250266908 0.1997941618785548 1.0 0.430142836353468 6 Q13126 1 +Regulation of chondrocyte differentiation 0.6554254180088301 1.2821079889032851 0.1998047668846791 1.0 0.430142836353468 6 Q92896,P16435 2 +Regulation of cartilage development 0.6554254180088301 1.2821079889032851 0.1998047668846791 1.0 0.430142836353468 6 Q92896,P16435 2 +T cell lineage commitment 0.6708451360237486 1.281724532574958 0.1999392958779622 1.0 0.430142836353468 5 P42345,P61586 2 +Positive regulation of g protein coupled receptor signaling pathway 0.670822491158672 1.2816220427228036 0.199975263862695 1.0 0.430142836353468 5 Q15043 1 +Fatty acid metabolic process 0.3075624368806635 1.2812794285461302 0.200095535835854 1.0 0.4302033560242875 104 O14678,Q53GQ0,Q15120,Q9NP80,P07099,O14734,Q16134,Q8NCG7,P04083,O15254,P23786,Q9P035,O14975,Q9BWD1,P28288,O95864,O15228,A1L0T0,O75477,Q15067,Q2T9J0,O43808,Q15118,Q709F0,P54646,Q9NWU1,O95470,Q9H7Z7,Q15800,Q8NCC3,A8MXV4,P16435,Q13510,P51648,Q8N4Q0,Q16836,P35610,Q9NZ01 38 +Regulation of mammary gland epithelial cell proliferation 0.6854590841835615 1.2803558380627276 0.2004200179897219 1.0 0.4304930140911802 4 Q9NQC3 1 +Development of primary female sexual characteristics 0.4964960872284997 1.2795547710052135 0.2007017652797253 1.0 0.4306752726506075 16 Q13315,O75874,O15360,O95470 4 +T cell activation 0.34280228886655 1.2746801979385811 0.2024224585299514 1.0 0.4335053764353666 55 P42345,Q92542,Q96J02,P78310,P24390,O15360,O96005,P61586,Q5HYI8,P30825,P04439,P04083,Q9NUQ9,P04062 14 +Regulation of blood circulation 0.3954625108398251 1.2746732018861062 0.2024249357930476 1.0 0.4335053764353666 31 O75844,P20020,P78310,P42892,Q9HD47,Q99959,P61586,P16615,P10253 9 +Response to ph 0.6692818897884331 1.2746492337510251 0.2024334229432645 1.0 0.4335053764353666 5 P51798,Q15907,P04062 3 +Regulation of cation transmembrane transport 0.3434825115159586 1.2741160677297332 0.202622284821472 1.0 0.4335053764353666 53 Q4KMQ2,P46934,Q9HD47,P21796,Q06787,P05067,Q96GC9 7 +Metencephalon development 0.3953907893224024 1.274000457072303 0.2026632541853128 1.0 0.4335053764353666 31 Q92542,Q86YH6,Q9UKA9,P27695,Q9BRK5,O15228,Q14103,P46108,P54802,O95487,O14949,P04062 12 +Regulation of actin filament based movement 0.5619818729215397 1.2735384508050176 0.2028270372537104 1.0 0.4336291697178777 10 Q9HD47,P16615 2 +Generation of precursor metabolites and energy 0.2829419894056884 1.273413604650094 0.2028713122575258 1.0 0.4336291697178777 186 Q99623,O75874,P51970,P52789,P11177,P48735,P24539,P05091,Q7KZN9,O15460,O95168,Q13423,Q9NZ45,O43676,O14949,P00403,P04062,Q9P0J0,O75306,P08574,O75964,Q9BRR6,Q15070,P22830,P10253,Q9BSK2,Q15067,P14406,Q9Y6M9,P03886,Q9UDW1,P54646,P05067,P61586,P13073,P12235,P23378,P42345,P16435,P35610 40 +Actin filament based transport 0.5720398689960401 1.272183143620464 0.2033080553070674 1.0 0.4342451428375031 9 O94832,O43707,O43795,Q9UH99 4 +Female sex differentiation 0.4836705366957923 1.2720424994037285 0.2033580194970508 1.0 0.4342451428375031 17 Q13315,O75874,O15360,O95470 4 +T cell activation involved in immune response 0.6172964868776398 1.2679753150035704 0.2048067660322723 1.0 0.4367009672598669 7 P42345,P04083 2 +Very long chain fatty acid metabolic process 0.5502946189651677 1.2678799149807214 0.2048408377363411 1.0 0.4367009672598669 11 O14678,Q9P035,O14975,P28288,Q15067 5 +Cellular response to lipid 0.3071780259134881 1.2676853228748264 0.2049103482395884 1.0 0.4367072767613443 100 P30536,P20020,O15173,Q15120,Q8TB36,P46934,Q86UE4,Q8WTV0,P61586,O15118,Q13315,Q9H7B4,Q14103,P08670,P04083,Q96HY6,Q9P0J0 17 +Regulation of potassium ion transport 0.4944074354509549 1.2656148103457865 0.2056510210777715 1.0 0.4376364963249938 16 Q4KMQ2,Q96PU5,P46934 3 +Aorta morphogenesis 0.6820400624476555 1.2653482737753223 0.2057465088635486 1.0 0.4376364963249938 4 Q96AY3 1 +Regulation of defense response to virus 0.4942872626129709 1.2648126840128742 0.2059384834200361 1.0 0.4379028931310036 16 O75844,Q96J02,Q07021,Q08211,P07900,O43657 6 +Negative regulation of blood pressure 0.6664118366528922 1.2616589507461762 0.2070715337967899 1.0 0.4398845596550778 5 Q9HB40 1 +Positive regulation of anion transport 0.5798155473085178 1.2608636337617118 0.2073579824780298 1.0 0.4401456721604206 8 P08183,P55011 2 +Mitochondrial fission 0.5265304641880723 1.2605400291868734 0.2074746171302242 1.0 0.4401708495339577 13 Q8TB36,Q9UDX5,Q9NQG6,Q9NUQ9,O60313 5 +Neuron development 0.2804432216149664 1.2603005533697924 0.2075609604494162 1.0 0.4402117073267838 203 P30536,Q13641,O00264,P35613,Q9UQB8,P50897,Q99707,O14949,P04062,Q14457,Q32P28,P33176,Q13277,P46108,Q14108,P42892,Q06787,P00374,P05067,Q9Y2A7,P61586,Q9NZJ7,Q96PU5,P08670,P54802,Q9NQX7,P46934,Q9NQC3,Q9HCE1,O75503,Q9NR77,Q96G23 32 +Regulation of systemic arterial blood pressure 0.5794466936200029 1.2588954543487794 0.2080680959294114 1.0 0.4407175098414454 8 P42892,P42785 2 +Cell cell signaling by wnt 0.3370018815540432 1.257864251428126 0.2084408541584781 1.0 0.441364596640185 65 Q8TAA9,Q13641,Q96K76,P54646,P05067,Q9H2V7,P61586,P50402,P48729,P52294,Q6DKJ4,Q5T9L3 12 +Lymphocyte activation 0.3064636214954571 1.2574808990513364 0.2085795513540449 1.0 0.4415158116081428 101 Q99623,P46379,P24390,P78318,P11279,O96005,Q13315,P30825,P04083,Q96FV9,Q96FZ2,P04062,Q96J02,Q9UQ84,Q96L92,O15360,P61586,Q96QE3,O96028,Q9NUQ9,P42345,Q92542,P78310,Q5HYI8,P04439 25 +Microtubule anchoring at microtubule organizing center 0.6652864381622932 1.2565652034484374 0.2089111214340908 1.0 0.4419621902668175 5 Q8TD16,Q15154 2 +Membrane raft organization 0.5789799567514254 1.256404962699956 0.2089691832728646 1.0 0.4419621902668175 8 P50897 1 +Negative regulation of telomere maintenance via telomerase 0.5787578625720669 1.2552198713906944 0.2093989537845861 1.0 0.4425132597692827 8 P09651,Q00839,P07910,Q9H0A0,Q9NVN8 5 +Chemical synaptic transmission postsynaptic 0.52560548317571 1.2548786572526374 0.2095228128776534 1.0 0.4425132597692827 13 Q9UQB8,P05067 2 +Regulation of postsynaptic membrane potential 0.52560548317571 1.2548786572526374 0.2095228128776534 1.0 0.4425132597692827 13 Q9UQB8,P05067 2 +Regulation of mitochondrial membrane potential 0.448082100374646 1.2533913938528296 0.2100633019584366 1.0 0.4435120294244726 21 P30536,Q9Y5Z4 2 +Regulation of phospholipid metabolic process 0.558070633439215 1.2515572268816093 0.210731248717783 1.0 0.4446361588701261 10 Q8WTV0,O75874,Q8NF37 3 +Response to muscle activity 0.664039354975503 1.2509207293444908 0.210963400110882 1.0 0.4448347884868602 5 Q9UDX5 1 +Peptidyl arginine n methylation 0.6486383601609464 1.2503919710822629 0.2111563960903593 1.0 0.4448347884868602 6 Q6P2P2,O14744 2 +Peptidyl arginine methylation 0.6486383601609464 1.2503919710822629 0.2111563960903593 1.0 0.4448347884868602 6 Q6P2P2,O14744 2 +Positive regulation of t cell proliferation 0.5777798610918338 1.250001246570937 0.2112990919639823 1.0 0.4448347884868602 8 P04439,P04083 2 +Tor signaling 0.4326731874747082 1.2487111398101542 0.2117707449385244 1.0 0.4456830109963429 24 O75844,P42345,P54646,P04062 4 +Linoleic acid metabolic process 0.6155303443015168 1.2476825819511683 0.2121473224626457 1.0 0.4462424036036856 3 Q9NP80 1 +Positive regulation of b cell proliferation 0.6142398599358053 1.2414981553798692 0.2144217791795251 1.0 0.4504619384564528 3 P14174,Q96QE3 2 +L aspartate transmembrane transport 0.6765541132678927 1.241268526726227 0.2145065673304669 1.0 0.4504619384564528 4 O75746,Q9UJS0 2 +Regulation of ire1 mediated unfolded protein response 0.6466770390103356 1.2412266581124831 0.2145220295148453 1.0 0.4504619384564528 6 O94874,P57088,Q96HY6 3 +Positive regulation of ossification 0.675938333309771 1.2385658125886216 0.2155063353787321 1.0 0.4520944337191707 4 Q4KMQ2 1 +Astrocyte development 0.6459888721842719 1.2380109007888132 0.2157120189259074 1.0 0.4520944337191707 6 P05067 1 +Meiosis ii cell cycle process 0.6757151196730741 1.237586119814266 0.2158695637093837 1.0 0.4522784409517802 4 O43683,P30153,Q96GX5 3 +Export across plasma membrane 0.6107080999788804 1.2351571899856426 0.2167720083807536 1.0 0.4540242320442085 7 P08183,P20020,Q4KMQ2 3 +Potassium ion transport 0.4309167079491812 1.234523792820385 0.2170077864068864 1.0 0.4541390036181815 24 Q4KMQ2,P55011,P46934,P33176,Q96PU5,Q9BXP2,Q9NUT2 7 +Positive regulation of cell death 0.2965230015761468 1.2342896720025969 0.2170949830606132 1.0 0.4541390036181815 131 P30536,P62753,Q9NS69,P52756,P30154,Q9Y6C9,Q13315,Q9UBN7,P04083,P98175,P49327,P00403,Q14457,O95831,Q4KMQ2,O14737,Q969S3,P78527,Q9Y5Z4,Q9NR28,P09601,P42858,P51572,P23246,P61586,Q9NZJ7,Q9Y4G8,Q7Z3C6,O75569,Q96A26,Q9NQX7,O94813,Q07021,Q07820,Q9Y5V3,Q9UHI6 36 +Cardiac muscle cell contraction 0.5006850065162762 1.2328998597637448 0.2176131277897841 1.0 0.4549147322575863 15 Q9HD47,Q99959,Q96PU5,P16615 4 +Peroxisome organization 0.5546331506864453 1.2322372890121072 0.2178604577604339 1.0 0.4550645755319227 10 P28288,O14678,O14734 3 +Response to endoplasmic reticulum stress 0.3042318634465538 1.2321505477283563 0.2178928522281775 1.0 0.4550645755319227 83 P46379,P57088,Q9UBV2,Q9UBU6,P16615,Q9UM00,O95831,Q8TCT9,Q15363,P14625,O75955,O95881,Q9Y4P3,O75477,P51572,Q5VYK3,Q6NTF9,Q13438,P27824,O76024,Q6ZXV5,Q9BUN8,Q8TCJ2,Q96JB5,Q96HY6,Q96A33,O60313 27 +Regulation of calcium ion transport 0.3717211464830673 1.230701642594983 0.2184344735279759 1.0 0.4559055392145605 37 P20020,P42858,P30536,P21796,Q06787,P61586,Q96GC9 7 +Regulation of synapse structure or activity 0.3811961277579517 1.2291010893178969 0.2190339068008955 1.0 0.4567705930092675 34 Q13641,P46934,P05067,P61586,O00264,Q9UQB8,P50897,P07437 8 +Leukocyte mediated immunity 0.3395855037208981 1.2262317520024253 0.2201114757207636 1.0 0.4586762475959514 53 P11279,P68371,Q96FV9,Q96FZ2,P33176,P52701,Q9UQ84,P46108,P07437,P09601,Q9H2U1,Q99584,Q96QE3,O96028,Q9NUQ9,Q07021,P01889,P04439,Q8N5M9 19 +Regulation of nitric oxide synthase activity 0.6085689676909982 1.2245022890619326 0.2207628033215383 1.0 0.4596936190100339 7 Q8WTV0,P00374 2 +Positive regulation of small molecule metabolic process 0.5204465525649073 1.2233004564865568 0.221216234820843 1.0 0.4599559356446047 13 P00403,P54646,P05067,P04083 4 +Potassium ion import across plasma membrane 0.6576763519526201 1.222123135582203 0.2216610653267341 1.0 0.460571733579935 5 P55011,Q9BXP2 2 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.4988091150771646 1.2207454089844023 0.2221824290233409 1.0 0.4613527445855767 15 Q96A26,Q9NZJ7,Q9BXK5 3 +Regulation of epithelial cell migration 0.339686745226984 1.2205216161506318 0.2222672002635721 1.0 0.4613527445855767 47 P42345,Q8WTV0,P61586,P57105,P42785,P04083,P09601 7 +Mitochondrial electron transport ubiquinol to cytochrome c 0.6572740090368534 1.22030242921786 0.2223502492669573 1.0 0.4613527445855767 5 Q9UDW1,O14949 2 +Regulation of glycoprotein metabolic process 0.5311625004686639 1.22003795977417 0.2224504851979221 1.0 0.4613527445855767 12 Q9NQX7,Q9Y287,P35610,O14734 4 +Cobalamin metabolic process 0.6714981909275929 1.2190794246344132 0.2228140484124994 1.0 0.4616690197924916 4 Q99707,O14678 2 +Er nucleus signaling pathway 0.5194562470768475 1.217238541230167 0.2235134701527044 1.0 0.4623882065391066 13 P57088,O76024,P16615,Q9UM00,Q96A33,O75477 6 +Regulation of receptor binding 0.6710150308262626 1.2169592262108424 0.2236197296349971 1.0 0.4624453642184117 4 O14786,P16615 2 +Response to abiotic stimulus 0.2784046426498332 1.2167954647119308 0.2236820460270099 1.0 0.4624453642184117 236 Q99623,P30536,P20020,P52789,Q15120,P51798,Q92974,Q9UNS1,Q13315,Q14103,O95202,P04083,Q15907,Q8N511,Q9BWF3,P00403,P04062,Q14457,O75844,P08183,O95831,O75306,P30519,P14625,Q9Y487,P49770,P22830,Q9Y4P3,Q7L576,P09601,P42858,Q9H2U1,P55011,Q15118,Q06787,P05067,P61586,Q70UQ0,Q9BRK5,Q13535,Q96A26,P42345,P46934,O95391,Q15904,Q9NQG6,P27544,Q92544,Q96K76 49 +Glycerolipid metabolic process 0.3198523524389045 1.2164833463124922 0.2238008512688258 1.0 0.4625452554412709 73 Q99623,Q9NP80,Q9UBV2,Q13315,Q8NCG7,Q14457,Q10713,Q8WTV0,O15228,Q96N66,Q6IAN0,O43292,Q9BZF1,Q9BTU6,Q9NXE4,Q8NCC3,Q9NPH0,Q9UG56,P52429,O60762,P48651,Q9NUQ2,Q8TBX8,Q8NF37,Q9H490 25 +Phosphatidylinositol biosynthetic process 0.4055434262703412 1.214581135259159 0.2245258874843116 1.0 0.4634598533098626 28 O43292,Q10713,P52429,O60762,Q9BTU6,Q13315,Q8TBX8,Q96N66,Q14457 9 +Regulation of protein neddylation 0.6556009514985044 1.2127317958602273 0.2252323792021147 1.0 0.4647719724290178 5 Q92564 1 +Multicellular organism reproduction 0.2951155271565373 1.2110150896928311 0.2258896215356645 1.0 0.465688877322347 137 Q9BQE5,P46379,P62753,O14965,Q13315,P35613,O14777,P04083,Q96MU7,Q8TAF3,O75592,P30153,Q9Y5A9,Q8N2A8,Q12768,Q96GX5,Q15363,P52701,Q9H2V7,Q01085,Q9Y2W6,Q8NB78,Q07666,P23634,P42574,Q15067,Q9H2U1,P51572,O60684,A0AVF1,Q96EP5,O15360,Q9H6S0,P05067,O95067,O95470,P41208,O75718,Q9BTX1,P42345,P78310,O94813,O94901,Q9UHJ3,P53350,Q9UHI6 46 +Regulation of potassium ion transmembrane transporter activity 0.5294578411847417 1.2099071935903825 0.2263145065917151 1.0 0.4662718343029308 12 P46934 1 +Dna replication checkpoint signaling 0.6398328762192497 1.2092474725469615 0.226567784434152 1.0 0.466647144211207 6 Q9Y619,Q9UNS1 2 +Reactive oxygen species biosynthetic process 0.5400458182189701 1.208679526265557 0.2267859903360987 1.0 0.4669500058316535 11 Q9BSK2,P00403,Q15067 3 +Antiviral innate immune response 0.6544739986713884 1.2076326952249636 0.2271885772052031 1.0 0.4673579327438845 5 Q9NVI7 1 +Response to axon injury 0.4622509741361271 1.2053338230471224 0.228074457420766 1.0 0.4685737600485494 18 P30536,P00374,Q96G23 3 +Aspartate transmembrane transport 0.668102158422006 1.204178274134842 0.2285206813292282 1.0 0.469196718048309 4 O75746,Q9UJS0 2 +Regulation of dna methylation 0.5593235555357926 1.2025797695639524 0.2291389802233192 1.0 0.4694380231737186 9 O75844,Q8NB78 2 +Neuron maturation 0.5679971150194555 1.1978053687064694 0.2309927966646032 1.0 0.4713229887167682 8 O75503,P05067 2 +Cellular response to vitamin 0.6521157102792101 1.1969633954590777 0.2313208224508771 1.0 0.4718455818845681 5 P20020 1 +Long term synaptic potentiation 0.5673859302500662 1.1945451420131228 0.2322647934633324 1.0 0.4734767240467186 8 Q14168,Q13277,P05067 3 +Cellular response to biotic stimulus 0.3599865322708224 1.1941101827352334 0.2324348705492451 1.0 0.4736762796720952 39 O75844,P30536,Q86UE4,Q8WTV0,P61586,P08670,Q9NUQ9,Q96A33 8 +Amyloid beta clearance 0.5575565168288323 1.192909748176708 0.2329047210479995 1.0 0.4744864264256358 9 Q16850 1 +Positive regulation of mononuclear cell migration 0.5575075914332642 1.1926420222326473 0.233009600892097 1.0 0.4745527625865737 9 Q4KMQ2,P05067 2 +Embryonic brain development 0.6505109489051047 1.1897042455491604 0.2341626561272054 1.0 0.4763097797602982 5 Q9BVA1,P27635,P62995,O60508 4 +Cytokine production involved in inflammatory response 0.6353805830225479 1.1884503191064208 0.2346560418879226 1.0 0.4766624376341987 6 Q8IV08 1 +Regulation of monocyte chemotaxis 0.6639879829384646 1.186130903265227 0.2355706081129347 1.0 0.4777509635930975 4 Q4KMQ2,O94813 2 +Cardiac muscle cell cardiac muscle cell adhesion 0.6346814598957857 1.1851852684429454 0.2359442032111152 1.0 0.4781549911894187 6 Q99959 1 +Regulation of ion transmembrane transport 0.3314437352482972 1.184188124934489 0.236338601813588 1.0 0.478806392436173 65 O75844,P08183,Q4KMQ2,P46934,Q9HD47,P21796,Q06787,P05067,Q96GC9 9 +Response to food 0.6490394627814898 1.183048830384592 0.236789795565635 1.0 0.4795075225820768 5 P80303 1 +Small rna loading onto risc 0.6631775625333213 1.1825766455724838 0.2369769728335378 1.0 0.4795075225820768 4 O75569 1 +Telomerase holoenzyme complex assembly 0.6336799447751484 1.180508331382205 0.2377980988142249 1.0 0.4807243143619668 6 Q13315,Q13535 2 +Cardiolipin metabolic process 0.599302071849837 1.1783573906282985 0.2386541570200666 1.0 0.4819522576842838 7 Q99623,Q9NP80,Q6UWP7,Q96BW9 4 +Defense response 0.2773646915135605 1.178302775263004 0.238675921798914 1.0 0.4819522576842838 219 Q9BQE5,Q99623,P10321,Q92974,Q13315,Q8NCG7,P04083,Q9BQ95,P04062,Q14457,O75844,Q9NUD5,Q4KMQ2,Q08380,P33176,Q13151,Q01085,P46108,Q9NZ08,P07437,P09601,Q9NVI7,O60506,O43657,Q6IAN0,Q9H2U1,O60684,P23246,O15360,P05067,P42785,P08670,Q03518,O00584,P42345,Q16543,Q9HCE1,Q96PK6,P01889,P04439,Q8IV08,Q8N5M9 42 +Regulated exocytosis 0.375635808646135 1.1744784367656371 0.2402034440253224 1.0 0.484368128568733 34 Q06787,P16615,Q9BRK5,Q4J6C6,Q15907,P09601 6 +Regulation of stem cell differentiation 0.4459381116857541 1.174140604719362 0.2403387117677224 1.0 0.484368128568733 19 Q9H2U1,Q96J02,Q00839,Q9Y6C9,P78527,Q96PZ0,Q9NX40 7 +Negative regulation of cellular macromolecule biosynthetic process 0.2990191360782817 1.171882876193335 0.2412440829134796 1.0 0.4860434977212937 114 Q14011,P67809,P11940,O14734,Q9UNS1,Q14103,Q9BWF3,Q9NVN8,Q10713,P07910,Q9Y287,O60506,Q9H2U1,P31483,Q06787,P00374,Q13535,Q92945,P51114,P34896,Q9NQX7,Q00839,P51116,Q9HCE1,Q969T7,Q96PZ0,P27544,Q08211 28 +Ubiquitin dependent erad pathway 0.3721816247722022 1.1696894278479275 0.2421259741961996 1.0 0.4872219082108132 35 P46379,P51572,O76024,Q5VYK3,Q9UBV2,Q9UBU6,Q9BUN8,P14625,Q8TCJ2,Q6NTF9,Q96A33,Q13438,O75477 13 +Regulation of nitric oxide metabolic process 0.5432897086844861 1.1684966897123767 0.2426064737386921 1.0 0.4877400982454957 10 P30536,P06280,Q92945,P07900 4 +Cell cell signaling 0.2755777172108384 1.1670319138847902 0.2431974816706827 1.0 0.4887785221203738 195 Q13641,O14786,Q9UIQ6,O00560,P16615,P53985,Q9UQB8,P50897,Q8NCG7,P04083,Q15907,Q6DKJ4,P43490,P33176,Q13277,Q9H2V7,P50402,Q7L576,Q14168,P22059,Q5T9L3,P55011,Q99959,P54646,Q06787,P05067,P61586,Q92542,Q15418,Q8TAA9,P78310,P52429,Q9HD47,O14936,P48729,P57105,Q4J6C6,P25398,P52294,P51812,Q9NR77,Q8N5M9,Q96K76 43 +Mitochondrial electron transport cytochrome c to oxygen 0.630736242372185 1.16676427354533 0.2433055784715638 1.0 0.4888460520301292 6 P13073,P00403 2 +Pore complex assembly 0.5006051653127067 1.1641963776580646 0.2443444378853372 1.0 0.4903327833038479 14 Q4KMQ2,Q9NQC3,Q6IQ23,Q9BTX1,Q8N1F7 5 +Cerebellar cortex development 0.5213509456681811 1.1617389285512023 0.2453415278462132 1.0 0.4918824032162698 12 P04062,P54802 2 +Response to ether 0.6579677275591722 1.1597351378288463 0.2461566593887805 1.0 0.4930647127317392 4 Q14103 1 +Ribosomal small subunit export from nucleus 0.5603540936139004 1.1570479595681704 0.247252766518119 1.0 0.4949581006381626 8 Q99567,P62841 2 +Lipid storage 0.4552522786180878 1.1555351906064788 0.2478713304646489 1.0 0.4960450352269064 18 Q8WTV0,P17900,Q14534,P04062 4 +Hindbrain development 0.3603462751286387 1.1543610709576235 0.2483521682578122 1.0 0.4967043365156245 38 Q9BRK5,O15228,Q14103,P46108,P54802,O14949,P04062,Q5T9L3 8 +Rna splicing via transesterification reactions 0.2762904733585169 1.1539427257320485 0.2485236509493806 1.0 0.496895855432613 188 P55769,Q14011,P78332,P61978,Q9BWJ5,P14866,P52756,P17844,P11940,Q13107,Q96MU7,P98175,Q9BWF3,P98179,P51991,Q13595,P07910,Q15427,Q07666,O60506,Q16637,P52597,O43390,P62995,P31483,Q9UKA9,P23246,Q96EP5,P31943,Q06787,O14744,P26368,Q92945,P51114,Q9UKM9,P22626,P62316,P31942,Q14562,Q6P2Q9,P38159,Q00839,P51116,Q07021,O95391,Q96PK6,Q08211,Q9UHX1,Q01081,Q9UHI6,O75400 51 +Inflammatory response 0.3208854440480763 1.1530927452052415 0.248872319065776 1.0 0.4974414126438082 70 Q9BQE5,P42345,Q4KMQ2,O60684,Q13151,P05067,P42785,Q13315,P04083,Q8IV08,P09601,P04062 12 +Skeletal muscle tissue regeneration 0.6563104685431376 1.1524722016712772 0.2491270863961601 1.0 0.4976474706032275 4 P52294,P04083 2 +Positive regulation of response to wounding 0.5594119141025642 1.1520260035174308 0.2493103879803373 1.0 0.4977106072184282 8 Q16625,Q4KMQ2,P04083 3 +Positive regulation of dna ligation 0.5355892648774951 1.1485984166675527 0.2507216102495693 1.0 0.4995343862940102 2 P09429 1 +Steroid esterification 0.5945030411627837 1.1469860348373722 0.251387392687479 1.0 0.5003348713422012 3 P35610 1 +Regulation of myeloid leukocyte mediated immunity 0.5489015338036847 1.1455672942226751 0.2519742363456205 1.0 0.5011988296150233 9 P09601 1 +Lens development in camera type eye 0.6393321528970201 1.1391702841248448 0.2546321371798108 1.0 0.5055903486864485 5 Q99797 1 +Maternal placenta development 0.6531912104735166 1.1388066112581636 0.2547838237043356 1.0 0.5055903486864485 4 Q96EP5,P35613 2 +Phosphatidylcholine metabolic process 0.5066068191008158 1.138609287047804 0.2548661531530274 1.0 0.5055903486864485 13 Q9NP80,Q8WTV0,Q96N66,Q8NF37,Q8NCC3 5 +Protein retention in golgi apparatus 0.5927485635372092 1.1385956748609298 0.2548718332387676 1.0 0.5055903486864485 3 Q96RL7 1 +Triglyceride metabolic process 0.5379303097088683 1.138402323722086 0.254952524200466 1.0 0.5055903486864485 10 Q9UBV2,Q8WTV0,Q96N66,Q8NCG7 4 +Regulation of amino acid transport 0.6245497451906702 1.1378952794793895 0.2551642126395421 1.0 0.5057044890790322 6 P55011 1 +Regulation of neutrophil migration 0.5559832603781607 1.133756400848663 0.2568967440357546 1.0 0.5080479432388624 8 O94813,Q8NE86,Q07021,Q8NHP6,P84095 5 +Anatomical structure maturation 0.3654931948151326 1.1335912732806666 0.2569660352956087 1.0 0.5080479432388624 36 Q8N2A8,O14965,O75503,P05067,P61586,Q9NZJ7,Q9Y2W6,Q8N5W9,P04062 9 +Regulation of programmed necrotic cell death 0.589847202845616 1.1313187611651108 0.2579209506310209 1.0 0.5097823126628793 7 P12235,Q13510 2 +Collagen biosynthetic process 0.6374709254600429 1.1307638643581053 0.2581544930177744 1.0 0.5100578781051307 5 Q92791 1 +Aging 0.3190512104653533 1.127672211952982 0.2594583773730918 1.0 0.5113909019468551 70 O75844,P20020,P30536,P67809,P05067,P04844,Q13315,Q13535,P04062,Q96MF7,O60313,Q9UGP8,Q14457 13 +Pons development 0.590419803912867 1.1274630353986503 0.2595467606633719 1.0 0.5113909019468551 3 O14949 1 +Organophosphate catabolic process 0.3451524471690631 1.1273558458719857 0.2595920594917669 1.0 0.5113909019468551 41 P49902,O75874,Q10713,Q9NP80,Q8WTV0,Q9H773,Q8NHP8,Q8NCC3,P35610 9 +Learning 0.4392583016093475 1.1249870346741353 0.2605945284131974 1.0 0.5130576944036609 19 Q13641,P05067,P50897,O00264 4 +Positive regulation of oxidoreductase activity 0.5450378890128794 1.1244500154985242 0.2608221641197454 1.0 0.5131562795995086 9 Q8WTV0,P00374 2 +Liver regeneration 0.5353351265939331 1.1238377625819391 0.2610818582118217 1.0 0.5133428289990405 10 P62841,P09601,O14744 3 +Segmentation 0.4939935707843262 1.122609522202343 0.2616033694514952 1.0 0.5136712897137561 14 Q8N2A8,Q8IZP0,O14786,Q9UK61,Q13315,Q9Y2W6,P78527 7 +Ribosomal large subunit export from nucleus 0.5878572224017063 1.1214266935790962 0.2621062790013075 1.0 0.5138886804778892 7 Q99567 1 +Monovalent inorganic anion homeostasis 0.5888180207898571 1.1198086254754007 0.2627953228388375 1.0 0.514742411783272 3 P55011 1 +Cognition 0.3700448055386961 1.1195429346581949 0.2629085849854282 1.0 0.514742411783272 34 P42858,P17900,Q13641,Q7L576,P05067,O00264,P50897,Q9H0U3 8 +Cell activation involved in immune response 0.3486743682778861 1.1183457654666698 0.2634193478775914 1.0 0.5155257264457964 40 P42345,P62753,P52701,P11279,Q99584,P05067,Q96QE3,Q9UQ84,O96028,P04083,Q96FV9,Q96FZ2,P09601 13 +Cell maturation 0.3944086415839712 1.116511555826889 0.2642032265314129 1.0 0.5167527429379225 28 Q8N2A8,O14965,O75503,P05067,Q9NZJ7,Q9Y2W6,P04062 7 +Lipid oxidation 0.3350459805558195 1.1165101736714786 0.2642038178233359 1.0 0.5167527429379225 43 Q2T9J0,P23786,O14678,O43808,P16435,O14975,Q709F0,O14734,Q9BWD1,P28288,Q16134,A1L0T0,P35610,O15254,Q15067 15 +Positive regulation of peptidyl tyrosine phosphorylation 0.4369558002968503 1.1080518453115236 0.2678394259443641 1.0 0.5215318436341002 19 P42345,Q8IZP0,O14786,Q92974,Q9H223,P22059 6 +Ventricular cardiac muscle cell development 0.5277129521587094 1.107181529827434 0.2682154514828276 1.0 0.5217995234599214 2 P02545 1 +Ventricular cardiac muscle cell differentiation 0.5277129521587094 1.107181529827434 0.2682154514828276 1.0 0.5217995234599214 2 P02545 1 +Rna interference 0.5508744228608143 1.1065534278117388 0.2684870523101734 1.0 0.5220183814101802 8 Q9HAV4,Q15631,P55265,Q9UPY3,Q08211,O75569 6 +Intrinsic apoptotic signaling pathway 0.2959430651344086 1.1062244994561945 0.2686293612521016 1.0 0.522085661283501 82 P46379,P61978,Q92974,P45880,Q13315,Q14457,O95831,Q9P0J0,Q969S3,P78527,O95881,Q9NR28,P09601,P23246,Q15118,Q96QE3,O75569,O76024,Q07820,O60313,Q96K76 21 +Purine nucleoside metabolic process 0.5504140423575177 1.1041033696777909 0.269548299722909 1.0 0.5230424811672126 8 O60725,Q13126 2 +Actin mediated cell contraction 0.4284307916900283 1.1035425866918565 0.2697916081931044 1.0 0.5231950024250388 21 Q9HD47,Q9UM22,Q96PU5 3 +Endoplasmic reticulum calcium ion homeostasis 0.5314303434561387 1.1019360094021162 0.2704894922482772 1.0 0.5241271307033795 10 O76024,P05067,P16615,Q9UM00,Q96A33 5 +Collagen metabolic process 0.521423948305309 1.1012071655265183 0.2708065038011418 1.0 0.5241983120776084 11 Q32P28,P08670,Q92791 3 +Positive regulation of amino acid transport 0.6303495596961817 1.0986249223069355 0.2719317023859842 1.0 0.5253854333955236 5 P55011 1 +Vasoconstriction 0.6302028946035694 1.0979634908004758 0.2722204318111521 1.0 0.5253854333955236 5 P61586,P42892 2 +Regulation of cholesterol metabolic process 0.6156213210668943 1.0962809522374235 0.2729558424740765 1.0 0.5264427457754671 6 O75477,Q9UBM7,P16435 3 +Synaptic transmission gabaergic 0.629795191242617 1.0961249357713896 0.2730241035532783 1.0 0.5264427457754671 5 P33176,Q13641 2 +Sex differentiation 0.3507126704839129 1.095482153404046 0.2733054599409072 1.0 0.5265503312190938 39 O75874,Q13315,O95470,Q15392,Q8TAF3,P49321 6 +Phosphatidylinositol metabolic process 0.3792612956623672 1.0914900669182293 0.2750573002905945 1.0 0.5293038136383815 30 O43292,Q10713,P52429,O60762,Q9BTU6,Q13315,Q8TBX8,Q96N66,Q14457 9 +Positive regulation of neurotransmitter uptake 0.5236289381563757 1.0857381544171778 0.277594855165987 1.0 0.5330926074331891 2 P05556 1 +Virion attachment to host cell 0.5233372228704941 1.084207455592483 0.2782728267185081 1.0 0.5340504885546664 2 P08238 1 +Adhesion of symbiont to host cell 0.5233372228704941 1.084207455592483 0.2782728267185081 1.0 0.5340504885546664 2 P08238 1 +Purine ribonucleoside metabolic process 0.5802388667470423 1.0835916114604422 0.2785459118134892 1.0 0.5341374264524009 7 O60725,Q13126 2 +Ribonucleoside metabolic process 0.5802388667470423 1.0835916114604422 0.2785459118134892 1.0 0.5341374264524009 7 O60725,Q13126 2 +Long chain fatty acyl coa metabolic process 0.5372537604460771 1.0819509442816388 0.2792743262018478 1.0 0.5352214160445459 9 Q96K12,Q9NZ01,Q53GQ0 3 +Regulation of multicellular organism growth 0.4873021071451786 1.0805640093904596 0.2798910993408388 1.0 0.5362015579440375 14 O75844,O95470 2 +Female meiosis i 0.6398442274048723 1.0804181227884486 0.2799560292129528 1.0 0.5362015579440375 4 O14965,O14777 2 +Ire1 mediated unfolded protein response 0.5795151495297655 1.0800007370762748 0.2801418519524459 1.0 0.5362575357386086 7 O94874,P57088,Q96HY6 3 +Axis specification 0.5174295657554715 1.0781958388165995 0.2809463685647926 1.0 0.5368579122079701 11 Q8N2A8,Q15363,O14965,Q9UK61,Q9Y2W6,Q5T9L3 6 +Associative learning 0.5063578976522772 1.0727824661747538 0.2833687295724492 1.0 0.5410141412436461 12 P05067,P50897,O00264 3 +Positive regulation of amine transport 0.6105134731465451 1.0725081840758528 0.2834918400059449 1.0 0.541091755124785 6 P55011 1 +Establishment of protein localization to vacuole 0.4200806265730918 1.072319927535482 0.2835763591700773 1.0 0.5410956873725058 22 Q96RL7,P46934,P13473,Q99523,Q14108 5 +Neural retina development 0.5778776738737335 1.0718784547963047 0.2837746285444944 1.0 0.5411592887268155 7 P54802 1 +Regulation of receptor mediated endocytosis 0.3770048277197915 1.0706578852077278 0.2843232857316971 1.0 0.5415760235040338 30 P61978,O00560,Q06787,P05067,P50897 5 +Bone morphogenesis 0.5350771930402557 1.0700811223694853 0.2845827955061786 1.0 0.541913030792671 9 O75844,P16435 2 +Bone remodeling 0.5248262431246608 1.0649363098453366 0.2869047523607944 1.0 0.544911428362238 10 O14773 1 +Cellular response to external stimulus 0.3265860210329854 1.0643370388008897 0.2871760447092124 1.0 0.5451111383806341 52 P20020,P42345,Q8TB36,P09601,P54646,P13473,Q9H773,Q9Y4P3,P21964,P04062,Q14457 11 +Negative regulation of cyclin dependent protein serine threonine kinase activity 0.6225694535166731 1.0635690910746114 0.287523950683519 1.0 0.5455847875656983 5 P42574,O95373,P53350 3 +Cellular iron ion homeostasis 0.4845707531535508 1.0634192668144675 0.2875918592181881 1.0 0.5455847875656983 14 Q8N511,P09601,Q9Y487 3 +Regulation of carbohydrate catabolic process 0.4639780649356152 1.0625748615723607 0.2879747921250826 1.0 0.5461533485331769 16 P54646,Q14108 2 +Positive regulation of blood circulation 0.6353730200751855 1.0608969099279528 0.2887367537443155 1.0 0.5467933981841073 4 P16615 1 +Dendrite extension 0.5747877097980925 1.056561090015545 0.2907119463679075 1.0 0.5495169785918822 7 Q96PU5 1 +Chondrocyte differentiation 0.5233246269872665 1.0565322768165124 0.2907251026159507 1.0 0.5495169785918822 10 Q15043,Q92896,P16435 3 +Cellular response to xenobiotic stimulus 0.3754278609516366 1.056103890022299 0.2909207533721729 1.0 0.5495169785918822 30 O15217,P54646,P07099,O43169,Q06520 5 +Response to organic cyclic compound 0.2749229360238826 1.0557010557908426 0.2911048146572041 1.0 0.5495482720887727 182 P30536,O75874,P20020,Q8TB36,P07099,P49721,P53985,P35613,Q14103,P04083,P04062,Q14457,Q9NUD5,P16278,P14625,P49321,P00374,P05067,P61586,Q9H7B4,O15173,P46934,P16435,O15118,Q13126,Q96HY6,P35610 27 +Regulation of hormone metabolic process 0.6202441967235498 1.0531054037428806 0.2922926865124942 1.0 0.5508399221410072 5 O75844 1 +Positive regulation of anion transmembrane transport 0.6322503266136053 1.0472773187030686 0.2949716938386393 1.0 0.55397946621899 4 P08183 1 +Regulation of dephosphorylation 0.35654087256133 1.043035218109165 0.2969319819804386 1.0 0.5564579481255559 36 P42345,P14625,Q96JB5,Q14738,P04062,Q86XL3 6 +Acylglycerol homeostasis 0.6311342971694066 1.0424127854590115 0.2972203413192993 1.0 0.5566095547195326 4 Q8WTV0 1 +Attachment of mitotic spindle microtubules to kinetochore 0.538723020174273 1.0419794906125417 0.2974211877697397 1.0 0.556826771510708 8 Q96DB5,Q00839,Q9BZD4,O14777,Q14457 5 +Negative regulation of catabolic process 0.2930254386657459 1.0401842424905008 0.2982543109053497 1.0 0.5577534552206412 103 P46379,P30536,Q14011,P67809,O00560,P11940,Q14103,P98175,Q14457,Q99729,Q13151,P07910,Q92530,Q9Y2S7,P09601,O60506,Q9H2U1,Q06787,Q16850,Q92804,P42345,P10619,Q00839,P35637,O15118,Q08211,Q07820,Q96JB5,Q96HY6,Q9NNW5 30 +Metal ion export 0.5383838401673899 1.0401802773135602 0.2982561527536163 1.0 0.5577534552206412 8 P20020,Q4KMQ2,O95202,P05023 4 +Fatty acid catabolic process 0.3244222835827244 1.0392603535064653 0.2986836681622489 1.0 0.5579597693892286 47 Q2T9J0,P23786,A8MXV4,O14678,O14975,Q709F0,O14734,Q9BWD1,P28288,Q16134,A1L0T0,Q8NCC3,P35610,O15254,Q15067 15 +Regulation of protein dephosphorylation 0.3796653088211715 1.038595296890154 0.2989929940302391 1.0 0.5579597693892286 29 P42345,P14625,P04062,Q14738,Q86XL3 5 +Lymphocyte mediated immunity 0.3529724431612451 1.0380716357250992 0.2992367055666802 1.0 0.5579597693892286 37 P07437,Q07021,P33176,P11279,Q96QE3,Q9UQ84,P46108,P68371,O96028,Q9NUQ9,Q96FV9,P01889,Q96FZ2,P04439 14 +Leukocyte homeostasis 0.5103984739218688 1.0377482473353994 0.2993872764818097 1.0 0.5579597693892286 11 P42574,P62753,Q99496,O95067,P04083,P49327 6 +Positive regulation of receptor mediated endocytosis 0.4899987221111246 1.037201600960679 0.2996419121194211 1.0 0.5579597693892286 13 Q06787,P50897 2 +Animal organ morphogenesis 0.2923712830751975 1.036561289407701 0.299940361978485 1.0 0.5581987110898523 107 Q99623,O14786,Q92896,P35613,Q8TAF3,P04062,O75844,Q16706,P53701,P10253,Q99959,P61586,O96028,O95470,Q6P4Q7,P54802,O75569,P42345,Q15418,Q8TAA9,P16435,Q9NQC3,Q9Y366,Q8N5W9,Q9Y5V3,O60568 26 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.6288542332606442 1.0324796843905322 0.3018474599020206 1.0 0.5612703405715669 4 P42892 1 +Forebrain generation of neurons 0.56975875633503 1.0316616853897975 0.3022306322240156 1.0 0.5615054950888987 7 O14786,O14949,P61586 3 +Lipoprotein catabolic process 0.6016048482833587 1.0311224181636265 0.3024834161548051 1.0 0.5618160704239544 6 Q9NUJ1,P50897 2 +Central nervous system neuron axonogenesis 0.6152489105125025 1.0306507037423798 0.3027046496891112 1.0 0.5619088857878213 5 P07900,O94813 2 +Metal ion homeostasis 0.2908085694682549 1.0299533302388388 0.3030319141738513 1.0 0.5620394066729261 81 P20020,P16615,O95202,Q8N511,Q9HD20,P30519,P14625,Q9Y487,Q8NE01,P09601,Q15043,P42858,P55011,P05067,Q96PU5,Q9BXP2,Q6P4Q7,Q8IYU8,O76024,Q16891,Q15904,Q96A33 22 +Hematopoietic stem cell homeostasis 0.6279923203430118 1.0287266446557832 0.303608145627684 1.0 0.5629490397312411 4 Q9NX40 1 +Cellular response to starvation 0.3633413114175457 1.0281390036395397 0.3038844458001584 1.0 0.5630568723540054 33 P54646,P13473,P04062,Q9Y4P3,P21964,Q14457 6 +Lymphocyte migration 0.5181171028252426 1.027417500364885 0.3042239144151102 1.0 0.5630568723540054 10 P46108,P61586,P05067,P04062 4 +Tissue regeneration 0.614470826586528 1.0271562579449771 0.3043468915286924 1.0 0.5630568723540054 5 P52294,P04083 2 +Olfactory lobe development 0.6274443780938066 1.0263412853422074 0.3047307433611923 1.0 0.5631211314942676 4 Q02218,O94813 2 +Post translational protein modification 0.4683068833716465 1.0234054524203495 0.3061161824994673 1.0 0.5649003098298621 15 O60725,Q32P28 2 +Neuron apoptotic process 0.3226076437061873 1.0232810605527298 0.3061749759076231 1.0 0.5649003098298621 55 Q96A26,O76024,O14786,P05067,P61586,Q13315,P50897,Q99720,P09601,P04062,O95831 11 +Positive regulation of smooth muscle cell migration 0.6267222453591397 1.0231982898484633 0.3062141013562969 1.0 0.5649003098298621 4 P46108 1 +Organonitrogen compound catabolic process 0.2526063277214333 1.0229737791565636 0.3063202435305432 1.0 0.5649003098298621 395 P46379,Q9UIQ6,Q9NP80,Q9UBU6,O00560,Q9UBV2,P49721,Q13042,Q13315,P06865,P06280,O60502,P50897,Q8N511,P21964,P08236,Q9BQT8,P04062,Q9P0J0,O75844,P49902,O14773,Q8TCT9,Q8WTV0,P16278,P30519,P14625,Q9H773,Q9UHG3,Q9NZ08,P09601,P17900,P42892,Q5VYK3,P28072,Q06787,P15586,Q99519,Q16850,Q96PU5,O95470,P54802,Q8NCC3,Q9NUJ1,A8MXV4,P42345,P10619,Q96RL7,P46934,Q6ZXV5,O75503,Q9BUN8,P13473,P48729,Q13126,Q96JB5,Q96HY6,Q96A33,Q13510,O76031,P35610,Q96K76 62 +Cell recognition 0.4045483332672573 1.0216095508129854 0.3069657354929069 1.0 0.5658171787372066 24 Q9NQC3,Q8WTV0,P05067,P45880,P35613,Q08431,Q14157 7 +Galactose catabolic process 0.56782088501283 1.0197652058208304 0.307839828483706 1.0 0.5669505906567721 3 P16278 1 +Galactose metabolic process 0.56782088501283 1.0197652058208304 0.307839828483706 1.0 0.5669505906567721 3 P16278 1 +Negative regulation of cellular amide metabolic process 0.291676369198636 1.019063509765168 0.3081728163903205 1.0 0.5672454477288313 91 O95197,P67809,P11940,Q14103,Q9BWF3,Q10713,O60506,Q9H2U1,P31483,Q06787,P00374,Q92945,P51114,P34896,Q00839,P51116,Q9NQC3,Q9HCE1,Q969T7,Q96PZ0,Q08211 21 +Cardiac conduction 0.4168896629495628 1.0157015022118998 0.3097715524650399 1.0 0.5693896154833591 21 O75844,P20020,P78310,Q9HD47,Q99959,P16615 6 +Positive regulation of gliogenesis 0.5159363422703631 1.015240379809323 0.3099912565460772 1.0 0.5696338911944437 10 P42345,P30536 2 +Negative regulation of amyloid precursor protein catabolic process 0.5662902752492076 1.0145125874587535 0.3103382261864076 1.0 0.5699597916571844 7 P27695,O95197,Q9NQC3 3 +Bile acid metabolic process 0.4857441263659588 1.0112977378112007 0.3118739484723674 1.0 0.5721837614612847 13 O14975,Q96SU4,O14734,O15118,Q06520,P22059 6 +Positive regulation of platelet derived growth factor receptor signaling pathway 0.5090431738623267 1.009397431474185 0.3127840697945965 1.0 0.5724806614029335 2 O75146 1 +Response to reactive oxygen species 0.3343097167824773 1.0078798967919962 0.3135121236692622 1.0 0.5735340271864227 41 P00374,Q9Y5Z4,P04083,Q99720,P09601,Q14457,O95831 7 +Animal organ regeneration 0.4342437753812264 1.0063385983393782 0.3142527191910365 1.0 0.5740917203583417 18 P62841,P09601,O14744 3 +Peroxisomal transport 0.5962300574391349 1.0062096480734728 0.314314732041943 1.0 0.5740917203583417 6 P28288,O14678 2 +Macromolecule depalmitoylation 0.6097492565491957 1.005971275498593 0.3144293878341786 1.0 0.5740917203583417 5 P50897 1 +Protein depalmitoylation 0.6097492565491957 1.005971275498593 0.3144293878341786 1.0 0.5740917203583417 5 P50897 1 +Peripheral nervous system development 0.4845937752421063 1.004300833537147 0.3152336320085005 1.0 0.5750883410943752 13 P51648 1 +Long chain fatty acyl coa biosynthetic process 0.5957943925233763 1.004192389885773 0.315285889523837 1.0 0.5750883410943752 6 O95573,Q53GQ0,P33121,O60488,Q9NZ01 5 +Microtubule anchoring at centrosome 0.6220778565588432 1.00300313702295 0.315859347670397 1.0 0.5757413998369848 4 Q15154 1 +Regulation of nucleotide biosynthetic process 0.5223401157522631 1.0007789250232706 0.3169337005679378 1.0 0.5772186908484063 9 Q15118,P00403 2 +Programmed cell death 0.255240966886514 0.9999807507068978 0.3173198234833696 1.0 0.5772810317986891 449 Q99623,P30536,P52789,P24390,Q9NS69,O14786,P21796,O14965,O95630,Q92974,P45880,P30154,P50897,Q15392,Q96FV9,Q99720,P04062,Q9UBK9,O75844,O43683,Q9UDX5,Q969S3,Q01085,P09601,P23246,P54646,Q96QE3,Q9NP92,P51114,Q99523,O95470,Q96A26,Q92542,Q9Y2I1,P52294,Q9UHX1,Q08211,Q07820,P51812,Q14728,Q14674,O95197,P78318,P11279,Q9Y6C9,Q9UBN7,P04083,Q9P0J0,Q86XL3,P07900,Q4KMQ2,Q96J02,O14737,Q9BXK5,P78527,Q9NR28,P51572,Q969H8,P05067,Q15041,Q9Y4G8,P12235,Q9NQX7,Q9P032,Q9H4A6,O94813,P16435,Q07021,Q04446,P27635,P05141,Q9BXJ9,Q13510,Q9UHI6,Q96K76,P46379,Q96GD4,P62753,Q86UE4,P27695,P17844,O75940,Q5J8M3,O43707,P98175,P49327,P30153,Q14457,O15269,Q03164,P52701,P14625,Q96KA5,P31483,Q15118,Q9Y2A7,P61586,Q9NZJ7,O75569,P42345,Q15418,Q9NQC3,Q96JB5,Q96HY6,O60313,P21127,P61978,P52756,Q13315,O95831,P12236,O95881,Q9NVI7,P42858,O43865,O76024,P53350,Q9Y5V3 118 +Positive regulation of protein localization to cell surface 0.5939870619667764 0.995827481379932 0.3193339752467472 1.0 0.5798152891580658 6 Q9HD47,Q92544 2 +Regulation of intrinsic apoptotic signaling pathway 0.3209916714066491 0.9949690078220136 0.3197513379742942 1.0 0.5802567145429532 50 P61978,Q96K76,O76024,P23246,Q92974,P45880,Q96QE3,O95881,O75569,O60313,Q9P0J0,Q14457 12 +Peptidyl asparagine modification 0.5296503161462984 0.9939281213069032 0.3202578624878631 1.0 0.5809798293774987 8 Q9H0U3,Q8TCJ2,P46977,P04844 4 +Negative regulation of neuron projection development 0.4138604325551348 0.9926960355066916 0.3208581075379542 1.0 0.5809798293774987 21 Q9NQX7,Q9NQC3,P61586,P08670,Q9NR77,Q96G23 6 +Plus end directed organelle transport along microtubule 0.5618640204163898 0.9915143605034836 0.3214344836902056 1.0 0.581862919165553 3 P33176 1 +Sprouting angiogenesis 0.4426044545096803 0.9895859518230452 0.3223765392583675 1.0 0.5829250070579796 17 P09601,P04083,P61586,P57105 4 +Fat soluble vitamin metabolic process 0.5925144115772613 0.9890159581181858 0.3226553339877283 1.0 0.5832684026521964 6 Q8N0U8,P04062 2 +Response to hormone 0.2673767240101908 0.9875640939794796 0.3233661784737272 1.0 0.5839076799469708 194 P30536,O75874,P20020,P35613,Q9UQB8,P04083,Q15392,P04062,O95831,P43490,P08574,P16278,P46108,Q7L576,P09601,Q9BSK2,Q15043,Q9BZF1,P54646,P61586,P42785,Q9H7B4,O43865,P42345,O15173,P46934,P16435,Q96PK6,O15118,Q8TBX8,Q96HY6,P35610 32 +Tetrapyrrole biosynthetic process 0.4817238232921051 0.9868588043894392 0.323711862074691 1.0 0.5839076799469708 13 P30536,P36551,Q7KZN9,O00264,P22830 5 +Regulation of leukocyte migration 0.3904349640364715 0.986840497357776 0.3237208381053154 1.0 0.5839076799469708 26 Q4KMQ2,P61586,P05067,P04083,P09601 5 +Macrophage differentiation 0.528137231607511 0.9859313186768452 0.3241668170359602 1.0 0.5845514298955676 8 P04062 1 +Hepaticobiliary system development 0.3402030368092784 0.9838709018683516 0.3251789923996186 1.0 0.5860271967011614 39 O75844,Q15418,O14965,O14744,P62841,Q14103,Q96JB5,P04083,P09601,P35610,Q9UGP8 11 +Endochondral bone morphogenesis 0.5905522006773112 0.979946401887247 0.3271125763960354 1.0 0.5883705241685836 6 O75844 1 +Response to lead ion 0.6038308788425607 0.9794694230880951 0.3273480895797651 1.0 0.5883705241685836 5 P05067,Q14457 2 +Regulation of cell shape 0.3604894119616663 0.9775768437760012 0.3282836547181271 1.0 0.5897063625130989 32 O75844,P61586,P46108,Q9UQB8,P04083,Q7L576 6 +Positive regulation of amyloid precursor protein biosynthetic process 0.5587839360478464 0.9769358073727378 0.3286009332159834 1.0 0.5900044176200157 3 P35610 1 +Negative regulation of endoplasmic reticulum unfolded protein response 0.6032514634777066 0.9768783048211388 0.3286294035966408 1.0 0.5900044176200157 5 Q96HY6,O76024 2 +Dna catabolic process exonucleolytic 0.501458576429421 0.9698930127932652 0.332099823234957 1.0 0.5944460011095984 2 Q9H0D6 1 +Sensory perception 0.3219204504833418 0.9663016597606952 0.3338932557829766 1.0 0.5965171642929192 43 Q99797,Q9Y5J9,Q9Y6M9,O76024,Q9Y5L4,P50897,O75569,Q9Y5J7,O60313,Q14108 10 +Neurotransmitter secretion 0.4285025499860583 0.965730413226338 0.3341790968739642 1.0 0.5968653330666721 18 Q4J6C6,Q06787,P50897,P16615 4 +Response to estrogen 0.468747126231661 0.964393596105946 0.334848631638575 1.0 0.5971030795352437 14 P04062 1 +Regulation of neutrophil chemotaxis 0.5558341757285779 0.9629557768693944 0.3355697166342386 1.0 0.597821633958983 7 Q07021,O94813,Q8NHP6 3 +Positive regulation of vacuole organization 0.5558115594496964 0.9628445177801612 0.3356255561574053 1.0 0.597821633958983 7 Q8TBX8 1 +L glutamate transmembrane transport 0.555545438187111 0.9615354446211456 0.3362830126005467 1.0 0.5981973566882681 7 O75746,Q9UJS0 2 +Positive regulation of gene expression 0.2679135423912495 0.9611542456281824 0.3364746180335869 1.0 0.5981973566882681 228 P67809,P11940,Q13315,Q9Y2R0,Q14103,P04083,Q567V2,Q96FZ2,P98175,Q9NUD5,O75844,P98179,O14737,Q99729,Q13151,Q13595,Q9NWS8,Q15427,P09601,O60506,O60684,Q06787,P05067,P61586,P08670,P51114,O96028,Q16625,Q96AE4,Q92804,P38159,P42345,P51116,P35637,P04439,Q96HY6 36 +Positive regulation of monooxygenase activity 0.5864032225973329 0.9607946508193462 0.3366554287228838 1.0 0.5983566964462522 6 Q8WTV0,P00374 2 +Positive regulation of toll like receptor signaling pathway 0.6122093961183205 0.9602141053862612 0.3369474691902687 1.0 0.5984453115702043 4 Q9NQC3 1 +Cellular response to exogenous dsrna 0.5994669740595632 0.959970462554786 0.3370700810063205 1.0 0.5984453115702043 5 Q08211,Q9NUD5 2 +Phosphatidylinositol 3 kinase signaling 0.4483486306937677 0.9587763654326515 0.3376714180615567 1.0 0.5991887088480085 16 Q10713,Q969H8,P46934,Q07021,O95630,Q14457 6 +Negative regulation of telomere maintenance via telomere lengthening 0.5141479023133175 0.9563884705201012 0.3388760074737513 1.0 0.6007455306793091 9 P09651,Q00839,P07910,Q9H0A0,Q9NVN8 5 +Response to alcohol 0.3210062945076471 0.9558666364901334 0.3391396168268512 1.0 0.6008363986266797 43 P20020,P30536,P54646,P16278,P61586,Q9BRK5,Q14103 7 +Methionine metabolic process 0.5542117952691301 0.9549776837109408 0.3395889825164992 1.0 0.6012245888357686 7 Q13126 1 +Negative regulation of atp metabolic process 0.4959403017063101 0.954895261247498 0.3396306664108857 1.0 0.6012245888357686 11 P30536 1 +Positive regulation of catabolic process 0.2767432336318636 0.9543075974203776 0.3399279634478449 1.0 0.601566153221348 165 P46379,Q86UE4,O14965,P21796,P67809,P11940,Q13315,Q14103,Q8NCG7,Q9P0J0,P04062,Q14457,O15269,O15270,P09601,O60506,P42858,P54646,Q06787,P05067,Q92945,Q96PU5,P12235,P46934,Q6ZXV5,Q969T7,Q9HCE1,P48729,Q8TBX8,P27544,Q96JB5,P53350,Q96HY6,Q8NF37 34 +Membrane repolarization 0.5220502772733018 0.9538176900853608 0.3401759332921843 1.0 0.6018426730286637 8 O75844 1 +Reproduction 0.2663229450519422 0.9529153039769378 0.3406329853479652 1.0 0.6023488742024081 248 Q9BQE5,Q99623,O75874,P55769,P46379,Q9UIQ6,O14965,P45880,Q13315,P35613,O14777,P04083,Q15392,Q8TAF3,O43683,Q12768,P07602,Q8N2A8,Q9BZD4,Q9H2V7,Q01085,Q9Y2W6,Q9UH99,Q9UQ84,P42695,Q8NB78,Q07666,P49321,Q96GC9,Q15067,O60684,A0AVF1,O15360,P05067,Q9NZJ7,O95470,P41208,O75718,Q92791,Q9BTX1,P42345,Q5TKA1,Q96RL7,O94901,Q9UHJ3,P53350,Q08431,Q14157 48 +Protein localization to vacuole 0.3913107838136611 0.9528436605640016 0.3406692890677569 1.0 0.6023488742024081 25 Q96RL7,P46934,Q9NQC3,P13473,Q99523,Q14108 6 +Regulation of lipid transport 0.4372116414049998 0.9527091997327028 0.3407374308197712 1.0 0.6023488742024081 17 P30536 1 +Regulation of reactive oxygen species biosynthetic process 0.5133345198345591 0.9519905959313224 0.3411017512000247 1.0 0.6026820613796976 9 Q9BSK2,P00403 2 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.6102624261629678 0.9517940477592988 0.3412014413327608 1.0 0.6026820613796976 4 Q16543 1 +Camera type eye morphogenesis 0.5129721895670013 0.9500321134314066 0.3420959354497015 1.0 0.6038212126006016 9 P54802 1 +Ovulation cycle 0.512678767556047 0.9484463708056056 0.3429022622968105 1.0 0.6038212126006016 9 P42574,O94813,P04083,O95470,O75592 5 +Vitamin metabolic process 0.3752715668289856 0.9483397243650812 0.3429565340031915 1.0 0.6038212126006016 28 O14678,P38435,P00374,Q9H2D1,Q8N0U8,P04062 6 +Early endosome to golgi transport 0.5526943248905298 0.947521286239536 0.343373214745293 1.0 0.6041669720568069 7 Q13190,Q9Y5X2,O15260 3 +Ethanol catabolic process 0.551676426528017 0.9433795503466664 0.3454867992478918 1.0 0.6064966229707508 3 Q06520 1 +Primary alcohol catabolic process 0.551676426528017 0.9433795503466664 0.3454867992478918 1.0 0.6064966229707508 3 Q06520 1 +Cardiac ventricle development 0.4651716325207729 0.9421109415204978 0.34613584324536 1.0 0.6073110704214044 14 O75844,P43243,Q99959,O96028 4 +Regulation of cellular respiration 0.4353801045097976 0.940207430587469 0.3471111710679817 1.0 0.6085341983831408 17 P14406,Q9BSK2,P61586 3 +Regulation of anion transmembrane transport 0.5817140128964213 0.9391938039427664 0.3476312496571447 1.0 0.6088146865521132 6 P08183 1 +Intermediate filament bundle assembly 0.6073432754240844 0.9391844399774836 0.3476360564946572 1.0 0.6088146865521132 4 P07197 1 +Regulation of wound healing 0.4247392882908543 0.9391723196138994 0.3476422783466577 1.0 0.6088146865521132 18 P42345,Q4KMQ2,P55011,O14936,P46108,P04083,Q16625 7 +Regulation of response to reactive oxygen species 0.4931135660123519 0.9387612076648478 0.3478533599732258 1.0 0.6089749284216831 11 Q9Y5Z4 1 +Carnitine metabolic process 0.5506926436660122 0.9376945207308538 0.3484014204717707 1.0 0.6096560323028691 7 P23786,Q9NVH6 2 +Detection of stimulus 0.4243904484847086 0.9367131940242104 0.3489061075275945 1.0 0.610362341290755 18 P30536,Q8WTV0,P04439,P01889 4 +Negative regulation of cell population proliferation 0.2861897180802329 0.9358417510576392 0.3493546715013278 1.0 0.610672710280158 108 Q99623,P30536,Q13641,P52756,Q13315,Q15392,P98175,Q14457,Q32P28,Q96J02,O14737,Q8IZP0,Q96DY7,Q01085,P50402,Q6YHK3,P09601,Q86U86,P05067,P61586,O75569,O14936,Q9Y366,P57105,Q9Y5V3,Q9NR77,Q96G23,Q9NNW5 28 +Regulation of membrane repolarization 0.5808244796929871 0.9351018762276408 0.349735799742954 1.0 0.610909789383524 6 O75844 1 +Mitochondrial translation 0.3145747215475324 0.933470193613928 0.3505772530088724 1.0 0.611753529358472 44 Q14197,Q5T653,Q5JPH6,Q07021,Q9Y2R0,Q9NWS8,Q567V2,Q9NVS2,Q9BW92 9 +Negative regulation of calcium ion transmembrane transport 0.5177079078902641 0.9309692615141868 0.3518694647849196 1.0 0.6128211569669961 8 P21796 1 +Vascular associated smooth muscle cell migration 0.6054293809580078 0.930927226059438 0.3518912099133864 1.0 0.6128211569669961 4 Q96N67,P61586 2 +Protein localization to endoplasmic reticulum exit site 0.6047869235259755 0.9281572871854238 0.3533259869375533 1.0 0.6148303172326239 4 P51572,O15027,Q92538 3 +Cell killing 0.4121188018537028 0.9260558969988072 0.3544169320806629 1.0 0.6160752075002146 19 P33176,P11279,P01889,P46108,P04439,Q9NUQ9,P07437 7 +Myotube differentiation 0.4530508695693033 0.925348995125005 0.3547844007270129 1.0 0.6163094406943836 15 Q8IV08,Q9H7B4,Q9BYT8 3 +Regulation of aerobic respiration 0.4811878785932409 0.9243416212790228 0.3553084791263901 1.0 0.6169618126103359 12 P14406,Q9BSK2 2 +Positive regulation of autophagy of mitochondrion 0.5782698628953724 0.923361097993588 0.3558190576118003 1.0 0.6175309854664464 6 P12235,P42858,P21796 3 +Positive regulation of granulocyte chemotaxis 0.5906647348014374 0.9207638233882977 0.3571737463047824 1.0 0.6187365689683162 5 Q07021,Q8NHP6,Q8NE86 3 +Positive regulation of neutrophil migration 0.5906647348014374 0.9207638233882977 0.3571737463047824 1.0 0.6187365689683162 5 Q07021,Q8NHP6,Q8NE86 3 +Regulation of synaptic vesicle exocytosis 0.4899028610431969 0.9204663901480424 0.3573290888047973 1.0 0.6188423015933175 11 Q4J6C6,Q06787,P16615 3 +Regulation of signal transduction by p53 class mediator 0.341211715238875 0.9176387019874048 0.3588080490114986 1.0 0.620642188622357 37 O75844,P42345,P61978,O14965,O14744,Q13315,Q13535,P62841,Q96JB5 9 +Response to arsenic containing substance 0.4606776493872413 0.9141665940263626 0.3606293145808228 1.0 0.622547849387422 14 Q13535,Q9H2U1,Q9BWF3,P09601 4 +Mitochondrial gene expression 0.3130416352383036 0.90861852851033 0.3635515227157828 1.0 0.6261483181262381 59 Q9Y2Z2,Q9Y2R0,Q9BSK2,Q9NWS8,Q567V2,O00411,Q9NVS2,Q9BW92 8 +Pigment metabolic process 0.3810580701738359 0.9083470270580848 0.3636949037492636 1.0 0.6261816923687541 26 P30536,P09601,P30519 3 +Regulation of transmembrane transport 0.2887505037541777 0.9046546253390412 0.3656483864712696 1.0 0.6282020791634706 78 Q99623,O75844,P08183,Q4KMQ2,P42858,Q9BZF1,P46934,Q9HD47,P21796,Q06787,P05067,Q96PU5,Q16625,O43865,Q96GC9 15 +Negative regulation of alpha beta t cell activation 0.5868797105946997 0.9039613773901548 0.3660158815358461 1.0 0.6282490752388757 5 P04083 1 +Positive regulation of vascular endothelial growth factor signaling pathway 0.4883313885647712 0.9019348116756708 0.3670914975987243 1.0 0.6297658581027004 2 Q12965 1 +Kinetochore organization 0.5731618402941242 0.8999352659550396 0.3681547012461013 1.0 0.6312597725573338 6 Q9BZD4 1 +Sulfur compound biosynthetic process 0.3116063118362572 0.8945664311087895 0.3710189032565421 1.0 0.6345129119545033 45 Q53GQ0,Q15118,Q9UL01,Q96L58,Q13126,P50897,Q8TB61,Q99707,P35610 9 +Response to starvation 0.3111779818844119 0.8940057395782446 0.3713188202480462 1.0 0.6348603695851169 44 P54646,P13473,O15228,P04062,Q9Y4P3,P21964,P35610,Q14457 8 +Regulation of transporter activity 0.3125092550136981 0.8929893110682058 0.3718628968372186 1.0 0.6351870443941758 50 P08183,P46934,Q9HD47,Q06787,P05067,Q96GC9 6 +3 phosphoadenosine 5 phosphosulfate metabolic process 0.5843372442433743 0.8926958337917452 0.372020082069084 1.0 0.6351870443941758 5 Q8TB61 1 +Ventricular compact myocardium morphogenesis 0.4862893815636092 0.8914191128935446 0.372704367848975 1.0 0.6357385136015009 2 Q9P2D1 1 +Monocarboxylic acid catabolic process 0.3120982569603908 0.8876163120439122 0.3747471761964926 1.0 0.6376619691316657 51 Q2T9J0,P23786,A8MXV4,O14678,O14975,Q709F0,O14734,Q06520,Q9BWD1,P28288,Q16134,A1L0T0,Q8NCC3,P35610,O15254,Q15067 16 +Dsrna processing 0.3998558665658314 0.8867748896402761 0.3752001092914925 1.0 0.6378401857955373 21 O75844,O75569 2 +Amyloid precursor protein catabolic process 0.4468887329966806 0.8859720047919353 0.3756326130426279 1.0 0.6382447454131861 15 P42574,Q92542,O95197,Q9NQC3,P27695,Q15392 6 +Peptidyl lysine hydroxylation 0.5088096274644138 0.8843333006795767 0.3765163169383025 1.0 0.6395071445605167 8 Q92791,Q96AY3 2 +Lysine metabolic process 0.5939821294708867 0.8817232764423898 0.3779264705080958 1.0 0.6408148577452519 4 Q9NRN7,Q9BQT8 2 +Homeostatic process 0.2498180810460663 0.8779558443393213 0.3799676816268609 1.0 0.6434446262801191 310 P30536,P20020,Q15120,P52789,P61916,Q9UIQ6,Q9NP80,P16615,P53985,Q9Y6C9,O95202,P50897,P04083,Q8TAF3,Q8N511,Q15907,Q9Y6M7,O15254,P04062,P23786,O14773,Q9HD20,Q4KMQ2,Q9P035,Q5BJF2,Q8WTV0,P30519,P14625,Q9Y487,Q8NE01,P10253,P09601,P22059,Q15043,Q15067,P42858,Q6IAN0,P55011,P62995,P54646,P05067,P42785,Q96PU5,Q9NX40,Q9BXP2,Q6P4Q7,Q16625,Q8IYU8,Q93050,O15260,Q14157,Q92542,O76024,P78310,Q9NQC3,Q9HD47,Q16891,Q15904,O75503,P05023,P13473,Q8NF37,O15118,Q14BN4,Q96JB5,Q07820,Q92544,Q96A33,P35610,Q8N5M9,Q9NUT2 71 +Cardiac muscle contraction 0.3906803783038296 0.8762402212355309 0.3808994551264342 1.0 0.6443573664706526 23 P42345,Q9HD47,Q99959,P16615,Q96PU5,P10253 6 +Regulation of exocytosis 0.3295981242005118 0.8717625856796277 0.383337909421362 1.0 0.6469813172898605 39 O00560,Q06787,P16615,P04083,P09601 5 +Non canonical wnt signaling pathway 0.5790761579278192 0.8694413778261165 0.3846057591829095 1.0 0.648814845248122 5 P61586 1 +Regulation of dna ligation 0.5357455500437805 0.86867898362892 0.3850227397352523 1.0 0.6493238802731242 3 P09429,Q9UBB9 2 +Receptor metabolic process 0.336377672782618 0.8683632361954887 0.385195514156438 1.0 0.6494483463243953 37 P42892,P46934,O00560,Q06787,Q15907,Q14457 6 +Cd4 positive alpha beta t cell activation 0.5057014935909523 0.8681092217048122 0.3853345432041108 1.0 0.6495158675842219 8 P04083 1 +Cell activation 0.2764275930832803 0.8668601241828081 0.3860186543439141 1.0 0.6502680015567218 136 Q99623,P46379,P24390,P78318,P11279,O96005,Q13315,P30825,P04083,Q96FV9,Q96FZ2,P04062,Q96J02,Q9UQ84,P09601,Q96L92,O15360,P05067,P61586,O14744,Q96QE3,O96028,Q9NUQ9,P42345,Q92542,Q15418,P78310,P52429,Q5HYI8,P04439,P52294 31 +Protein maturation 0.2984445298418562 0.8647729225401984 0.3871634357621514 1.0 0.6508572714952086 71 Q8TCT9,Q99797,O75844,Q2T9J0,Q10713,Q9BU23,P42892,Q9UG56,O75503,P67812,Q92896,Q86UY6,Q9BU89,Q5JRX3,Q15392 15 +Positive regulation of alpha beta t cell activation 0.504969365410159 0.8642929933407058 0.3874269582268088 1.0 0.6510360307002099 8 P04439,P04083 2 +Ubiquinone metabolic process 0.5770089212135008 0.8603262986683893 0.3896092000073463 1.0 0.6534895634747397 5 Q5T2R2,Q86YH6 2 +Nadp metabolic process 0.4328771706422323 0.8568341040676792 0.3915365748593236 1.0 0.6560937191590606 16 O75874,P48735 2 +Carbohydrate derivative biosynthetic process 0.2726514160534755 0.8564236948422582 0.3917634629452786 1.0 0.6563063170403162 162 Q7LGA3,Q8WVC6,Q15120,P11177,Q53GQ0,P24539,O14734,P06865,O60512,O60502,P50897,Q9H0U3,P00403,Q2TAA5,P32321,Q16706,Q8N4A0,O75964,P46977,Q8TB61,Q9Y287,O43292,Q86YN1,Q15118,Q10472,Q9UL01,Q96L58,P34896,Q8NBX0,Q9NQX7,Q92542,O60476,O60762,Q6ZXV5,Q9BT22,O15118,P04844,Q8TCJ2,Q13126,Q8NAT1,Q9H490,P35610,O60568 43 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.3450697168530102 0.8521826327468114 0.3941127343255481 1.0 0.6592321597359794 33 P42345,P01889,Q9UQ84,O96028,P04439,P04083,Q96FV9,Q9NUQ9,Q96FZ2 9 +Macropinocytosis 0.4778296382730501 0.8480402018380756 0.3964155821227217 1.0 0.6621379437707982 2 P50570 1 +Membrane invagination 0.4499782090146116 0.8479688010823676 0.3964553460950115 1.0 0.6621379437707982 14 Q4KMQ2,P61586,Q14457 3 +Mitochondrial transcription 0.5016211395401159 0.8468677795978157 0.3970688234816761 1.0 0.6625127474679066 8 Q9BSK2 1 +Cellular response to potassium ion 0.5855430083404835 0.845676790128754 0.3977330744003979 1.0 0.6625855380084822 4 Q14168 1 +Response to potassium ion 0.5855430083404835 0.845676790128754 0.3977330744003979 1.0 0.6625855380084822 4 Q14168 1 +Response to fatty acid 0.4766320049475856 0.8452558454642549 0.3979680081093502 1.0 0.6626404641495954 11 P23378,O15228,Q15120 3 +Ribosomal subunit export from nucleus 0.4581330217340576 0.8445133575686034 0.3983826023108912 1.0 0.6631625155667347 13 Q99567,P62841,Q96D46 3 +Response to l glutamate 0.5848809383105654 0.8428579506853354 0.3993078930322289 1.0 0.6636261038644796 4 Q9UQB8 1 +Positive regulation of attachment of spindle microtubules to kinetochore 0.5605703414837239 0.8425129021534236 0.3995009208595097 1.0 0.6636261038644796 6 Q00839,Q96GD4,Q14457 3 +Interleukin 6 production 0.4489109191646064 0.8413949757173281 0.4001266992293006 1.0 0.6642123451410753 14 P01889,P05067,Q92974,P04062 4 +Gpi anchor metabolic process 0.5594021595705669 0.8372114906133801 0.402473699727865 1.0 0.6672223274450113 6 O60762,O43292 2 +Transcription coupled nucleotide excision repair 0.5834792761237545 0.836894816796321 0.402651694099702 1.0 0.6672223274450113 4 Q93009,Q9HCS7,P18074 3 +Regulation of phosphatidylinositol 3 kinase signaling 0.4749126921727095 0.8355670109693476 0.4033985338661039 1.0 0.6680469933955754 11 O95630,Q10713,Q14457,P46934 4 +Gdp metabolic process 0.5831434588722835 0.8354670792059142 0.4034547751945543 1.0 0.6680469933955754 4 Q14168 1 +Positive regulation of endothelial cell migration 0.3929765630030239 0.8351014998229696 0.4036605623007081 1.0 0.668219124575491 21 P09601,P04083 2 +Regulation of production of molecular mediator of immune response 0.3619233785027339 0.8319286798787857 0.4054492023490457 1.0 0.6702371604300587 28 Q99623,Q9H2U1,O96028,P04439,Q96FV9,Q96FZ2,P09601 7 +Regulation of immune effector process 0.306796140513526 0.8310827856037702 0.4059268637559481 1.0 0.6706173413813019 47 Q99623,Q9H2U1,Q96QE3,P01889,P46108,O96028,P04439,P04083,Q96FV9,Q9NUQ9,Q96FZ2,P09601 12 +Regulation of presynaptic cytosolic calcium ion concentration 0.5274949697043821 0.8303289989285765 0.4063527966908746 1.0 0.6711520392362245 3 P20020 1 +Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.5693556025850945 0.8266991354756128 0.4084076115001356 1.0 0.6738674243560195 5 Q99729 1 +Regulation of low density lipoprotein particle clearance 0.569213811681428 0.8260779902670787 0.4087598521120317 1.0 0.6739402385827015 5 P61978 1 +Response to chemokine 0.5566729066739885 0.824844462811372 0.4094598999712324 1.0 0.6749248589829759 6 P55011,P61586 2 +Monocyte chemotaxis 0.5269543926127099 0.8220907885079483 0.411025227695599 1.0 0.6761114636981709 7 P04083 1 +Regulation of protein tyrosine kinase activity 0.4540390057314322 0.8200538866552809 0.4121853885383442 1.0 0.6772059388053616 13 O95684 1 +Regulation of response to wounding 0.3868879639570391 0.8166087139946092 0.4141520736634771 1.0 0.6797563550224456 22 P42345,Q4KMQ2,P55011,O14936,P46108,P04083,Q16625,Q96G23 8 +Vascular endothelial growth factor receptor signaling pathway 0.4714244919729325 0.8159541659878231 0.4145263505561458 1.0 0.6801232174699561 11 O14786,O14964,P46934 3 +Positive regulation of dna demethylation 0.4714119019836695 0.8153541745405541 0.4148696071244742 1.0 0.680253463755822 2 Q93009 1 +Head development 0.2694436486615736 0.814217941992108 0.4155201087230276 1.0 0.6806397786920886 166 P46379,P20020,P24539,Q13315,Q14103,Q9UQB8,P50897,O14949,P04062,Q16352,O15228,P46108,Q96N66,Q5T9L3,P05067,P61586,Q9BRK5,O95470,P54802,O75569,Q9NQC3,O75503,P14854,O94901,Q96JB5,P35610 26 +Positive regulation of calcium ion transport 0.393340047154425 0.8126318684413723 0.4164291544065257 1.0 0.6815092702371199 20 P20020,P42858,P30536,O76024,Q96GC9 5 +Pigment granule localization 0.553894367107705 0.8122821142773953 0.4166297710786324 1.0 0.6815092702371199 6 Q15907 1 +Positive regulation of stem cell differentiation 0.5660427005902587 0.8122049117875345 0.416674061595752 1.0 0.6815092702371199 5 Q9Y6C9 1 +Receptor mediated endocytosis 0.3051230848349754 0.8106567556893239 0.4175628138361673 1.0 0.6826879237112987 60 P61978,Q5VW38,P46934,O00560,Q06787,P05067,P50897,Q14108 8 +Positive regulation of glucose transmembrane transport 0.5762373047831783 0.8061894243788442 0.4201336356535408 1.0 0.6848479698570556 4 Q16625 1 +Response to extracellular stimulus 0.2779242192114161 0.8061151456147289 0.4201764594094035 1.0 0.6848479698570556 89 P30536,P42345,P20020,P80303,Q8TB36,P16435,P54646,P13473,P53985,P21964,Q9H773,O15228,Q9Y4P3,P09601,P35610,P04062,Q14457 17 +Acetyl coa biosynthetic process from pyruvate 0.4935519773880688 0.8050734461057864 0.4207772980107598 1.0 0.6854867501357015 8 Q15118,Q15120 2 +Cell cycle g2 m phase transition 0.3045774993668182 0.8048030991655529 0.4209333129758748 1.0 0.6855707122729437 61 Q96GD4,O14965,Q13315,O14777,Q9ULX6,P08183,Q92547,Q96GX5,Q9Y619,Q07666,Q5TBB1,Q7L7X3,Q6NUQ1,P05067,Q96QE3,O95067,Q9Y570,P53350,Q96JB5,Q96K76 20 +Cytosolic calcium ion transport 0.3683238133805852 0.802533582364329 0.422244370545167 1.0 0.6872922182277184 26 P20020,P21796,P16615,O95202,Q8IYU8 5 +Negative regulation of receptor internalization 0.5516447845713288 0.8021328433301093 0.4224761183612295 1.0 0.6872922182277184 6 O00560 1 +Terpenoid metabolic process 0.4149602215446665 0.8018723741307039 0.422626787932888 1.0 0.6872922182277184 17 Q9HB40,P51648,P37268 3 +Cell death in response to oxidative stress 0.3682235648362173 0.8017052687621732 0.4227234673524949 1.0 0.6872922182277184 26 P23246,Q15118,Q969S3,Q9UBN7,Q07820,Q99720,P04062 7 +Negative regulation of neuron differentiation 0.4848461995703306 0.7994258997568868 0.4240434975257505 1.0 0.6889263260123731 9 P61586,P05067 2 +Autophagosome maturation 0.3941343528012132 0.7958455327323596 0.4261218227757322 1.0 0.6914469339897019 19 P13473,Q96GC9,P16615 3 +Intermediate filament based process 0.4233602795745013 0.7947222035686646 0.4267751136253772 1.0 0.6923357961952349 16 P07197,P08670,Q16352,P48729 4 +Negative regulation of calcium ion transport 0.4757537420516837 0.7934496891045705 0.4275158705187745 1.0 0.6928684243684194 10 P21796 1 +Regulation of dna templated transcription in response to stress 0.4495656140416263 0.7934326533112639 0.4275257924821289 1.0 0.6928684243684194 13 P09601,P46934 2 +Cholesterol efflux 0.4835360682136903 0.7924944899861804 0.4280724033058312 1.0 0.6933669257941055 9 Q8WTV0,P35610,O15118 3 +Cardiac septum morphogenesis 0.520090038174781 0.7890545235576197 0.4300801398990259 1.0 0.6959767886602733 7 O14786,O96028 2 +Positive regulation of chemokine c c motif ligand 5 production 0.4661610268378096 0.7887713321297232 0.4302456678278608 1.0 0.6960729961258437 2 O00571 1 +Negative regulation of smooth muscle cell proliferation 0.5197954899610391 0.7876416194011033 0.4309063629921401 1.0 0.6969654174348442 7 P09601 1 +Mitotic g2 dna damage checkpoint signaling 0.4220598402089254 0.7862786680551491 0.4317042469883687 1.0 0.6972148932991948 16 Q92547,Q6NUQ1,Q13315,Q96JB5,P53350 5 +Intestinal epithelial cell differentiation 0.4655775962660519 0.7858272152341159 0.431968720183403 1.0 0.6972148932991948 2 Q9NQ88 1 +Intestinal epithelial cell development 0.4655775962660519 0.7858272152341159 0.431968720183403 1.0 0.6972148932991948 2 Q9NQ88 1 +Positive regulation of histone phosphorylation 0.570613114255934 0.7824725001525075 0.4339369406349362 1.0 0.6975918818527537 4 Q06787 1 +Histamine production involved in inflammatory response 0.5170703238984682 0.7822718808731252 0.434054808534714 1.0 0.6975918818527537 3 P51809,Q9UNH7 2 +Positive regulation of mast cell activation 0.5170703238984682 0.7822718808731252 0.434054808534714 1.0 0.6975918818527537 3 Q92692,P51809 2 +Histamine secretion 0.5170703238984682 0.7822718808731252 0.434054808534714 1.0 0.6975918818527537 3 P51809,Q9UNH7 2 +Histamine transport 0.5170703238984682 0.7822718808731252 0.434054808534714 1.0 0.6975918818527537 3 P51809,Q9UNH7 2 +Regulation of histamine secretion by mast cell 0.5170703238984682 0.7822718808731252 0.434054808534714 1.0 0.6975918818527537 3 P51809,Q9UNH7 2 +Regulation of defense response to bacterium 0.4644107351225237 0.779944922651588 0.4354232949491572 1.0 0.6994486319354638 2 Q8IXJ6 1 +Negative regulation of defense response to bacterium 0.4644107351225237 0.779944922651588 0.4354232949491572 1.0 0.6994486319354638 2 Q8IXJ6 1 +Positive regulation of actin cytoskeleton reorganization 0.5585216014931126 0.779452013779882 0.435713494300507 1.0 0.6995884256142488 5 O14786,Q9UQB8 2 +Positive regulation of protein localization to membrane 0.3500601159365084 0.7741093412353994 0.4388661338981507 1.0 0.7032279980883716 29 O14737,Q9HD47,P33176,Q13277,O00264 5 +Regulation of cell population proliferation 0.2595136982946536 0.7740398552031278 0.438907222824912 1.0 0.7032279980883716 240 Q99623,P30536,Q13641,P52756,O14786,O95630,O00560,Q92974,Q9UNS1,Q13315,P30825,P04083,Q15392,Q8TAF3,P98175,Q14457,O75844,Q32P28,Q15022,P43307,O14737,P43490,Q13277,Q96DY7,P50402,P09601,Q9BSK2,Q9UKA9,O95684,O15360,P55209,P05067,P61586,O75569,P16435,Q9NQC3,P57105,P04439,Q8NEM2,Q9Y5V3,Q96HY6,Q14534,Q9NR77,Q96G23,Q9NNW5 45 +B cell differentiation 0.4291799999678216 0.7738670839182822 0.439009396629245 1.0 0.7032279980883716 15 Q5HYI8,Q07812,P05141,Q13315,P78527,Q8IWT6 6 +Nuclear envelope organization 0.3500020675854464 0.7735968981588456 0.4391692069744204 1.0 0.7032279980883716 29 O75844,Q9UH99,P50402,O94901,P53350,Q8N1F7,Q86XL3 7 +Forebrain neuron development 0.5567513124932897 0.7717754734246937 0.4402474206165057 1.0 0.7041035637153047 5 O14786,O14949 2 +Neuron projection guidance 0.3645935172992124 0.7717704683439346 0.4402503855228248 1.0 0.7041035637153047 26 P42892,P33176,P05067,O00264,P35613,Q7L576 6 +Negative regulation of response to wounding 0.4635231436526241 0.7717668945371126 0.4402525025790758 1.0 0.7041035637153047 11 O14936,P46108,P55011,Q96G23 4 +Negative regulation of oxidoreductase activity 0.5564639331061725 0.7705305344512143 0.4409852495009732 1.0 0.7049419434364004 5 P06280,Q9UBN7,Q15070 3 +Nucleoside bisphosphate catabolic process 0.5677677151842804 0.7705198761957877 0.4409915693091166 1.0 0.7049419434364004 4 P35610 1 +Cellular response to steroid hormone stimulus 0.3021911401332084 0.7693423395240737 0.4416901087467146 1.0 0.7057147537365331 54 Q99623,P20020,O15173,Q00839,P05023,P46934,P61586,O15118,Q9H7B4,P04083,Q96HY6,O95831 12 +Viral protein processing 0.486444049895468 0.7685200441101462 0.44217828707299 1.0 0.7063227652806623 8 Q10472,P48729,Q16706 3 +Anion homeostasis 0.5655467252757163 0.7612128726735641 0.4465299307435364 1.0 0.709818169946484 4 P55011 1 +Regulation of cell death 0.2408180453107046 0.7601150722213418 0.4471858040597429 1.0 0.7106886040784773 358 Q99623,P30536,Q9NS69,O14786,P21796,O14965,O95630,Q92974,P45880,P30154,P50897,Q15392,Q99720,P00403,P04062,Q969S3,Q9Y5Z4,P09601,Q6NUK1,P23246,P54646,Q96QE3,Q96A26,O15118,P52294,Q07820,P51812,P78318,Q9Y6C9,Q9UBN7,P04083,Q9P0J0,Q86XL3,P07900,Q4KMQ2,Q96J02,O14737,Q9BXK5,P78527,Q9NR28,P51572,Q969H8,Q15041,Q9Y4G8,Q7Z3C6,P12235,Q9NQX7,Q9P032,Q9H4A6,O94813,P16435,Q07021,Q04446,P27635,P05141,Q9BXJ9,Q13510,Q9UHI6,Q96K76,P46379,Q96GD4,P62753,Q86UE4,P27695,O43707,P98175,P49327,Q14457,O15269,P14625,P61586,Q9NZJ7,O75569,Q15418,Q9NQC3,Q96HY6,O60313,P61978,P52756,Q13315,O95831,O95881,Q9NVI7,P42858,O76024,P53350,Q9Y5V3 87 +Negative regulation of cell size 0.564642828823255 0.757430961192289 0.448791712912667 1.0 0.7120992454951288 4 P61586 1 +Myeloid leukocyte differentiation 0.3371012814557508 0.7566456914599806 0.4492621594812029 1.0 0.7124355462821783 32 P42345,Q15904,P05067,P04062,Q8N5M9,Q14739 6 +Midbrain development 0.3821987221667778 0.7548047129828784 0.4503661656190276 1.0 0.7131877231934284 21 Q16352,P24539,P61586,P14854,O14949 5 +Import into cell 0.3577147083589522 0.7534030366113361 0.4512077585921992 1.0 0.7140635390641967 27 P55011,P05023,P11166,O14975,O75955,Q15041,P30825,P23634,Q9BXP2,Q15758,Q15043 11 +Response to retinoic acid 0.45140750193458 0.7517256716930792 0.452216048871753 1.0 0.7152151938644188 12 Q13315,Q9P0J0,Q8TB36 3 +Transcytosis 0.4831501306228959 0.7516732151151975 0.4522476018619235 1.0 0.7152151938644188 8 P55899 1 +Regulation of gtp binding 0.5117423064374818 0.7491732830441187 0.4537527699330781 1.0 0.7167851892876405 7 O75503,P48729 2 +Acidic amino acid transport 0.4509059724137432 0.7488605902453251 0.4539412357588765 1.0 0.7169103222743076 12 O75746,Q9UJS0,P55011,Q15041 4 +Regulation of generation of precursor metabolites and energy 0.3271172355563791 0.7480458005212439 0.4544325321605416 1.0 0.7173277295243877 36 P14406,P54646,P05067,P61586,Q9NZ45,Q9BSK2 6 +Establishment of rna localization 0.2749016318323304 0.7475892240008902 0.4547079665467617 1.0 0.7173277295243877 95 Q8TD16,P67809,Q13315,Q96MU7,Q9ULX6,Q96FV9,Q5SRE5,P51991,Q7Z3B4,Q99567,Q07666,Q06787,Q13535,Q92945,P22626,P41208,Q9BTX1,Q8N1F7,Q9HAV4,Q12769,Q8NFH4,Q08211 22 +Positive regulation of reactive oxygen species metabolic process 0.4418096928009097 0.7475677648754993 0.4547209142941444 1.0 0.7173277295243877 13 P30536 1 +Embryonic heart tube morphogenesis 0.5094215520295808 0.7473349067236522 0.4548614267831419 1.0 0.7173277295243877 3 Q9Y366 1 +Response to acid chemical 0.3615902930309954 0.7470973951759176 0.455004772441165 1.0 0.7173813831712937 26 P42574,P42345,Q6IAA8,Q99729,P61586,Q14103,Q9UQB8,P23634,O94874,Q9P2J5,O95831 11 +Regulation of platelet derived growth factor receptor beta signaling pathway 0.5091917128684124 0.7462897082535674 0.4554924271133229 1.0 0.7179777340181661 3 Q07954,O75146 2 +Regulation of mrna metabolic process 0.2671390428366163 0.7433322760145855 0.4572805353019618 1.0 0.7202772137905601 161 P21127,P61978,P52756,P67809,P11940,Q14103,P98175,Q9BWF3,P98179,Q99729,Q13151,Q13595,Q15427,Q07666,O60506,P31483,Q06787,Q92945,P08670,P51114,P22626,P38159,Q92804,P51116,Q9HCE1,Q969T7,P35637,Q9UHX1 28 +Negative regulation of ion transmembrane transporter activity 0.4407611620557611 0.7413981423923613 0.4584520704852899 1.0 0.7210840092340538 13 Q06787,P46934 2 +Positive regulation of blood vessel endothelial cell migration 0.4579428859109835 0.7407826759071056 0.4588252209152665 1.0 0.7211691413665675 11 O14786,P09601,P04083 3 +Central nervous system neuron development 0.4403258165737703 0.738838834748749 0.4600048671509642 1.0 0.721796254960456 13 O94813,O14786,Q9Y4G8,O14949,P07900 5 +Developmental maturation 0.2983708448376109 0.7366406200662624 0.4613409260040457 1.0 0.7235466435082573 46 Q8N2A8,O14965,O75503,P05067,P61586,Q9NZJ7,Q9Y2W6,Q8N5W9,P04062 9 +Regulation of lymphocyte mediated immunity 0.368350011384537 0.733130625704198 0.4634787626468024 1.0 0.7256854308013165 24 Q96QE3,P01889,P46108,O96028,P04439,Q9NUQ9,Q96FV9,Q96FZ2 8 +Multi organism reproductive process 0.2650535269413415 0.7322472800245732 0.4640176511487826 1.0 0.7259757413513006 167 Q9BQE5,P46379,P55769,P62753,Q9UIQ6,O14965,P45880,Q13315,P35613,O14777,Q96MU7,Q8TAF3,O75592,P30153,Q9Y5A9,Q8N2A8,Q12768,Q96GX5,Q15363,P11166,Q9H2V7,Q01085,Q9Y2W6,Q8NB78,Q07666,Q96GC9,Q15067,Q9H2U1,P51572,O60684,A0AVF1,Q96EP5,O15360,Q9H6S0,P05067,O95067,O95470,P41208,O75718,Q9BTX1,P42345,P78310,Q07021,O94901,Q9UHJ3,P53350,Q08431,Q14157,Q9UHI6 49 +Alpha beta t cell activation 0.4136493199316973 0.7319649105539279 0.4641899853068343 1.0 0.7259757413513006 16 P04439,P61586,P04083 3 +Endothelial cell migration 0.3228317855669673 0.7314464186855489 0.4645065211225203 1.0 0.7259757413513006 37 Q8WTV0,P57105,P42785,P04083,P09601 5 +Cellular response to peptide 0.2805443568835974 0.7300797579278455 0.4653414336032484 1.0 0.727040592215361 76 P20020,Q9BZF1,P43490,P16435,P05067,Q92974,P46108,Q9UQB8,P08670,Q8TBX8,Q7L576,O43865,Q9BSK2,Q15043 14 +Multicellular organismal response to stress 0.5353438078764944 0.7292307704594864 0.4658605118606429 1.0 0.7276783334514494 6 P30536 1 +Primitive hemopoiesis 0.4542007001166982 0.728835136343102 0.4661025157883824 1.0 0.727709899739083 2 Q13769 1 +Negative regulation of vascular associated smooth muscle cell proliferation 0.5345819207883604 0.7258536752531101 0.4679284778580765 1.0 0.7298778609862687 6 P09601 1 +Secretory granule organization 0.5460917449841807 0.7258413742225786 0.4679360196844304 1.0 0.7298778609862687 5 P22059 1 +Positive regulation of proteolysis 0.2731836954796892 0.7254600128416476 0.4681698677499755 1.0 0.7298956218045471 92 Q96A26,P46379,Q96HY6,O14737,Q6ZXV5,Q06787,P05067,P61586,Q9BXK5,Q9NZJ7,P48729,Q96JB5,P04062,Q8TAF3,O76031,Q9P0J0 16 +Response to increased oxygen levels 0.4628756723241039 0.7239353407088682 0.4691054320821417 1.0 0.7308244287383305 10 Q8N511,Q9Y487 2 +Coenzyme a metabolic process 0.4625291698500059 0.7220794105073607 0.4702456561262056 1.0 0.7313671772709328 10 Q8WVC6,P35610 2 +Regulation of endocytosis 0.2978549741426229 0.7168910085016469 0.4734413504311154 1.0 0.7341025854274527 56 P61978,Q4KMQ2,O00560,Q06787,P05067,P57105,Q96PU5,P50897 8 +Regulation of myotube differentiation 0.5432494742469592 0.7136831810796122 0.4754231088014051 1.0 0.7352643035481548 5 Q9BYT8 1 +Mononuclear cell migration 0.3731660677734565 0.7128600703522964 0.4759323496884939 1.0 0.7357050833111655 22 Q4KMQ2,P05067,P61586,P04083,P04062 5 +Oocyte maturation 0.5034766451897873 0.7100429952716775 0.4776774743345664 1.0 0.7370137753546732 7 O14965,P30153,Q12768 3 +Ossification 0.2971035952264345 0.7095136145618823 0.4780058058683942 1.0 0.7371861181554941 60 P20020,P18074,P17844,P49327,O75844,Q4KMQ2,P06576,P07910,O60506,Q9H2U1,P61586,Q99523,P38159,Q00839,Q8N5W9,P62841,O75165,O94874,Q08211,Q9UNW1,Q96A33 21 +Regulation of peptidyl tyrosine phosphorylation 0.3348561721144037 0.7095006351656438 0.4780138574751031 1.0 0.7371861181554941 31 P42345,Q8IZP0,O14786,O95684,P05067,Q92974,Q9H223,P22059,P30153 9 +Lymphocyte activation involved in immune response 0.3474175944148168 0.707031337016465 0.4795470039256901 1.0 0.738682497596333 28 P42345,P62753,P11279,Q96QE3,Q9UQ84,O96028,P04083,Q96FV9,Q96FZ2 9 +Central nervous system development 0.2554349003615652 0.7046093186579706 0.4810533977249638 1.0 0.7399607116435096 201 P46379,P20020,O14786,P24539,Q13315,Q14103,Q9UQB8,P50897,O14949,P04062,P07900,Q86XL3,Q15154,O14773,Q15022,Q16352,P11166,P00367,P49770,O15228,P46108,Q96N66,Q5T9L3,P62995,Q9UKA9,Q9Y2A7,P05067,P61586,O14744,Q9BRK5,P08670,O75569,P54802,P42345,Q92542,Q9NQC3,O75503,P51648,P14854,O94901,Q96JB5,P51812,O95487,P35610,Q9Y320 45 +Neutral lipid metabolic process 0.4092370920814487 0.7036972560830547 0.4816213295041209 1.0 0.7406049545342227 16 P52429,Q9UBV2,Q8WTV0,Q9NUQ2,Q8NCC3,Q96N66 6 +Cyclic nucleotide metabolic process 0.4489498249708328 0.7028244289893066 0.4821651711984089 1.0 0.7409760780805527 2 Q01433 1 +Positive regulation of immune effector process 0.316519922837999 0.700288393556436 0.4837472185820055 1.0 0.7427115695683482 38 Q99623,Q9H2U1,Q96QE3,P01889,O96028,P04439,P04083,Q9NUQ9,Q96FZ2,P09601 10 +Cell cell signaling involved in cardiac conduction 0.5397910630745142 0.698944156479694 0.4845869306397681 1.0 0.7432390540756937 5 Q9HD47,Q99959 2 +Peptidyl serine modification 0.26924300208752 0.6988752100774638 0.4846300210597429 1.0 0.7432390540756937 81 Q96GD4,Q15120,O14965,Q13315,Q9UBN7,P07900,Q96GX5,Q8N4A0,O95429,P78527,P23634,P54646,Q10472,P05067,Q14012,Q9H7B4,Q13535,P42345,P04049,Q15418,P48729,P53350,P51812 23 +Vascular associated smooth muscle cell proliferation 0.4580255548437144 0.6980332416837558 0.4851564055710533 1.0 0.7433099073913734 10 P09601,P61586 2 +Immune effector process 0.276553902924179 0.6976658027511997 0.4853862192298876 1.0 0.7434044916413789 77 Q99623,P42345,Q9H2U1,P07437,P33176,P05067,P01889,Q9UQ84,P46108,P04439,O96028,P04083,Q96FV9,Q9NUQ9,Q96FZ2,P09601,Q8N5M9 17 +Negative regulation of intrinsic apoptotic signaling pathway 0.3306657626408039 0.6967718511940532 0.4859455847664282 1.0 0.7437495559157831 32 O76024,Q92974,P45880,Q96QE3,O95881,O60313,Q9P0J0,Q96K76 8 +Anaphase promoting complex dependent catabolic process 0.4497159277674395 0.6954857518696476 0.4867509372864558 1.0 0.7443625379803596 11 Q9UJX4,Q9UJX2,Q9H1A4,Q13042,P53350 5 +Male sex differentiation 0.3633479600162793 0.6940666070765567 0.4876404389212139 1.0 0.744875016474863 24 Q8TAF3,P49321,O95470,Q15392 4 +Receptor internalization 0.3632821750315457 0.6935547153050883 0.48796150123998 1.0 0.74499845768654 24 O00560,Q06787,P46934 3 +Tricarboxylic acid cycle 0.3704079122945708 0.6922245586129566 0.4887963183011545 1.0 0.745925916440041 22 O75874,P48735 2 +Regulation of cytoplasmic translational initiation 0.4967168945907213 0.6900056039095818 0.490190663262281 1.0 0.7465968313226076 3 P42345 1 +Positive regulation of organelle assembly 0.3501166636056165 0.6899285993285939 0.4902390897175084 1.0 0.7465968313226076 27 Q9P2W9,Q9P2S5,O00560,P61586,Q8TBX8,Q14457 6 +Positive regulation of lymphocyte apoptotic process 0.4463243873979085 0.689895441013969 0.4902599430309351 1.0 0.7465968313226076 2 Q07812 1 +Negative regulation of mitophagy 0.446324387397907 0.6898954410139613 0.49025994303094 1.0 0.7465968313226076 2 Q9NQ88 1 +Regulation of transcription from rna polymerase ii promoter in response to hypoxia 0.4463243873979027 0.6898954410139401 0.4902599430309533 1.0 0.7465968313226076 2 Q8IXJ6 1 +Endomembrane system organization 0.2607224294019243 0.6892060479576121 0.4906936113952092 1.0 0.7470838695998521 174 P46379,Q9P2W9,P57088,O95197,Q8TBA6,P16615,Q5J8M3,Q9UQB8,Q9ULX6,Q86XL3,Q13190,O75844,Q9H6U6,Q4KMQ2,Q6IAA8,Q12768,Q15363,Q13277,Q9UH99,P49257,P50402,O43681,Q8NHH9,Q14108,P22059,Q96GC9,Q9NPA0,P42858,Q9BTU6,O14744,Q9NXE4,Q15041,Q9Y3B3,Q8NFQ8,Q7Z3C6,Q8N1F7,O15260,Q9H4A6,Q9NQC3,P48729,Q12907,O94901,Q15629,P53350,Q96A33,Q8N5M9 46 +3 utr mediated mrna stabilization 0.5262102602607477 0.6889456443655012 0.4908574740473217 1.0 0.7471599964505974 6 Q13151,P98175 2 +Positive regulation of organic acid transport 0.4985165831327738 0.686752070705568 0.4922389777400777 1.0 0.7485866917062678 7 P55011 1 +Response to iron ion 0.470218488205102 0.6861778284921791 0.4926009772501505 1.0 0.7485866917062678 8 P09601 1 +Cd4 positive alpha beta t cell differentiation 0.5245513048821778 0.6816773946710682 0.4954429643940878 1.0 0.7512863899128769 6 P04083 1 +Er associated misfolded protein catabolic process 0.4972860391497436 0.680997466645309 0.4958730934260149 1.0 0.7514825032474618 7 P46379 1 +Production of sirna involved in rna interference 0.5456272946600129 0.6787327957092288 0.497307182276907 1.0 0.7530437804228671 4 O75569,Q15631 2 +Leukocyte migration 0.2938731557567679 0.6770988871157825 0.4983432149672566 1.0 0.7538331435258502 48 Q4KMQ2,P55011,Q9H4A6,P78310,O94813,P05067,P61586,P35613,P46108,P04083,P09601,Q8N5M9,P04062 13 +Ovulation cycle process 0.5233913298310742 0.6766046800742205 0.4986568089232222 1.0 0.7538533933955709 6 O75592,O95470,O94813 3 +Regulation of toll like receptor signaling pathway 0.4608636734104481 0.6741617311950806 0.5002084965676965 1.0 0.7552618855216807 9 Q9NPR9 1 +Embryonic heart tube development 0.4673335511042488 0.6717208761651712 0.501761408621126 1.0 0.7572581332501905 8 Q9Y366,P42892 2 +Positive regulation of vasculature development 0.3676308238532419 0.6715336805079625 0.5018806108450042 1.0 0.7572638694791717 22 Q9NZ08,P09601,P52789,Q86UE4 4 +Acetyl coa biosynthetic process 0.4367992863178414 0.6690237592808217 0.5034803220093516 1.0 0.7582827342266157 12 Q15118,P35610,Q15120 3 +Granulocyte differentiation 0.4932781770808417 0.66232310031512 0.5077641753707565 1.0 0.7622851793143226 7 Q6IAN0,Q8N5M9,Q14739 3 +Cardiac chamber development 0.3844927274168037 0.6603230697687174 0.5090465286582686 1.0 0.7639823379151337 18 O75844,O14786,P43243,Q99959,O96028 5 +Positive regulation of cell activation 0.308826481388777 0.6554702519423365 0.5121650333267358 1.0 0.7672228946523443 39 Q15418,P11279,P61586,Q96QE3,P30825,O96028,P04083,Q9NUQ9,P04439,Q96FZ2 10 +Negative regulation of transporter activity 0.410077624689562 0.655394363718822 0.5122138794202651 1.0 0.7672228946523443 15 Q06787,P46934 2 +Regulation of glycolytic process 0.4497588404145213 0.6542891011172167 0.5129255662759622 1.0 0.7672228946523443 10 P54646 1 +Regulation of er to golgi vesicle mediated transport 0.518257977371829 0.6542518510505528 0.512949560843541 1.0 0.7672228946523443 6 Q9P2W9,Q6NUQ1 2 +Interleukin 1 production 0.4340998106499575 0.6539286579513213 0.5131577696783205 1.0 0.7672228946523443 12 P04083 1 +Neurotrophin signaling pathway 0.4491567442155336 0.651124429931326 0.5149661675496704 1.0 0.7692255842160112 10 P42574,P27695,Q9ULH0,Q9Y4G8,Q99523,Q7L576 6 +Response to camp 0.4412824176646824 0.6495890090641308 0.5159577344924966 1.0 0.7698794864220583 11 P21953,P35613,Q9Y4G8,P05067 4 +Negative regulation of dna biosynthetic process 0.4243825986881666 0.6461453472330103 0.5181852298838572 1.0 0.7719254207713668 13 P09651,Q00839,P07910,Q9H0A0,P27544,Q9NVN8 6 +Regulation of protein localization to cell surface 0.4165505060561764 0.6456391911860606 0.5185130500697592 1.0 0.7720632254499116 14 Q9HD47,Q96PU5,Q15907,Q92544 4 +Histone serine phosphorylation 0.5270677837200538 0.645280976660799 0.5187451182766725 1.0 0.772233544948168 5 O14965,P54646 2 +Protein neddylation 0.4616488641110398 0.6434171138573994 0.519953481609948 1.0 0.7729802325157406 8 Q92564 1 +Protein lipid complex subunit organization 0.5156592232435129 0.6429976796319054 0.5202256055124372 1.0 0.7731912054973468 6 Q8WTV0 1 +Export from cell 0.2641560753989521 0.6428351815685963 0.5203310520384461 1.0 0.7731912054973468 142 P20020,Q9UBV2,O00560,P16615,P53985,P04083,P50897,Q15907,P08183,Q32P28,Q4KMQ2,Q13277,Q9UPT5,P09601,P22059,Q96KC8,Q06787,Q9BRK5,Q16850,Q96PC5,Q4J6C6 21 +Cellular response to osmotic stress 0.4458086974930729 0.6335831085913779 0.5263529272577596 1.0 0.7794917419691759 10 P11166,P30536,O95202,Q92974 4 +Alpha beta t cell differentiation 0.437434574463811 0.6288500012114995 0.5294472617441965 1.0 0.781780587660985 11 P61586,P04083 2 +Positive regulation of leukocyte migration 0.4056007697009006 0.6281119511324573 0.5299306045501107 1.0 0.782005304849632 15 Q4KMQ2,P05067 2 +Positive regulation of atp dependent activity 0.3617556084358059 0.6280717125294142 0.5299569629177558 1.0 0.782005304849632 22 Q9UBS4,Q00839,Q04837,Q8NFQ8,Q08211,Q96GC9 6 +Negative regulation of protein secretion 0.4581933759088102 0.6263381917229324 0.5310931409585504 1.0 0.7829775760435875 8 Q16850,Q8N5M9 2 +Positive regulation of epithelial to mesenchymal transition 0.5111558387823119 0.6235988901853308 0.5328910396563251 1.0 0.7847466342515272 6 O00560 1 +Renal tubule development 0.4844478457305071 0.6215714040138443 0.5342237291769156 1.0 0.786356238416088 7 P35610 1 +Skeletal system development 0.2898693470435458 0.6209876228787216 0.534607766854192 1.0 0.7863923259576794 53 O75844,Q32P28,Q96HY6,P16435,Q15904,P61586,Q92896,O96028,O75569,O95470,Q8TAF3,Q15043 12 +Osteoclast differentiation 0.4280428901745882 0.6203009983860164 0.535059637748946 1.0 0.7868806236908525 12 P42345,Q15904 2 +Entry of bacterium into host cell 0.5205337196872434 0.618097648379098 0.5365109723595267 1.0 0.7883008289780299 5 Q9BTY2,Q9UPT5 2 +Coenzyme a biosynthetic process 0.5098432957872694 0.6179705392182453 0.5365947588537685 1.0 0.7883008289780299 6 P35610 1 +Forebrain neuron differentiation 0.509832232625463 0.6179231491424374 0.5366259986353032 1.0 0.7883008289780299 6 O14786,O14949 2 +Negative regulation of calcium mediated signaling 0.479655835087701 0.6146459330951022 0.5387885730008783 1.0 0.7900627074931316 3 P42345 1 +Negative regulation of calcineurin mediated signaling 0.479655835087701 0.6146459330951022 0.5387885730008783 1.0 0.7900627074931316 3 P42345 1 +Ensheathment of neurons 0.3451563103001508 0.6139376841424448 0.5392565069170603 1.0 0.7901155730794642 26 P42345,Q92542,P49770,O15228,Q7L576,Q9NR77 6 +Glycine metabolic process 0.4551067528573961 0.61116747507679 0.5410887132892892 1.0 0.7921963713976609 8 P23378,P00374 2 +Cellular response to acid chemical 0.3945497328028818 0.6109486749731187 0.5412335593031776 1.0 0.7922316788194181 16 Q99729,Q14103,Q9UQB8 3 +Protein localization to axon 0.4782608695652266 0.6085781160334873 0.5428041135301336 1.0 0.7936879116342441 3 Q12955,Q9Y2J2 2 +Intracellular sterol transport 0.4479706058066091 0.6085342713647756 0.5428331830866333 1.0 0.7936879116342441 9 P22059,O15118 2 +Positive regulation of protein localization to cell periphery 0.3648251019276777 0.6073267556977314 0.543634085584888 1.0 0.7939743756082874 20 Q9HD47,P33176,O00264 3 +Negative regulation of lipoprotein particle clearance 0.4776443946095615 0.6059014444551278 0.5445802002246278 1.0 0.7944720484379741 3 Q92945 1 +Positive regulation of mitotic nuclear division 0.4170114821154943 0.6040713204271306 0.5457962260688942 1.0 0.7958264737183833 13 Q9UJX4,Q14674,O14965,Q13042,Q96MF7 5 +Phagocytosis 0.2969879676609251 0.6037244949678044 0.5460268259188235 1.0 0.7958596439996002 41 Q8WTV0,Q4KMQ2,P04083,Q92544 4 +Cardiac muscle cell action potential involved in contraction 0.4396782650305307 0.6017241444194706 0.547357775525958 1.0 0.7965761195389967 10 Q99959,Q96PU5 2 +Anterior posterior pattern specification 0.363707584286449 0.5994721855402126 0.5488580527166633 1.0 0.7984053517904555 20 Q8N2A8,Q15363,Q8IZP0,O14965,Q9UK61,Q13315,Q9Y2W6,P78527,Q5T9L3 9 +Regulation of neurotransmitter levels 0.325039765844202 0.5991469654721313 0.5490748851257112 1.0 0.7985402410997763 30 Q13277,Q06787,P16615,Q4J6C6,P50897,Q8NCG7,P21964 7 +Regulation of adaptive immune response 0.351000899988126 0.5989680889854643 0.5491941645966611 1.0 0.7985402410997763 24 Q96FV9,P01889,O96028,P04439,Q9NUQ9,P04083,Q96FZ2 7 +Mitochondrial electron transport nadh to ubiquinone 0.3543089786169193 0.5974674187938314 0.5501953534521042 1.0 0.7998187659177466 23 O75306,Q9Y6M9,P51970,O96000,P03886,O95168,O43676 7 +Response to vitamin 0.4003475203036227 0.5963755517619548 0.5509243692254941 1.0 0.8003472144228488 15 P20020,P30536,Q14457 3 +Positive regulation of alpha beta t cell differentiation 0.504780863019154 0.5963749455898049 0.5509247740853411 1.0 0.8003472144228488 6 P04083 1 +Adenylate cyclase inhibiting g protein coupled receptor signaling pathway 0.4446927600734988 0.5920816594545985 0.5537959077341634 1.0 0.8036286480653649 9 Q9NZJ7,P07602 2 +Dendritic transport 0.5037252249128834 0.5918949670478222 0.5539209242610803 1.0 0.8036323468939219 6 P23246,P33176 2 +Negative regulation of mitochondrion organization 0.3908550893041176 0.5879937501334882 0.5565364878466204 1.0 0.8067135925004468 16 P30536 1 +Negative regulation of translational initiation 0.4766850390440832 0.5862337481618959 0.5577184456450652 1.0 0.8078785911409178 7 Q06787 1 +Canonical wnt signaling pathway 0.3163900246148592 0.5824354596656529 0.560273402549502 1.0 0.8096265288548408 33 Q96K76,Q13641,P48729,P50402,P52294,Q5T9L3 6 +Regulation of canonical wnt signaling pathway 0.3163900246148592 0.5824354596656529 0.560273402549502 1.0 0.8096265288548408 33 Q96K76,Q13641,P48729,P50402,P52294,Q5T9L3 6 +Diencephalon development 0.4491537755392368 0.5821484679470245 0.5604666806409051 1.0 0.8097275117493657 8 O14786,P27695,Q07812,O75569,O14949 5 +Positive regulation of posttranscriptional gene silencing 0.3971559580216086 0.5772517911615206 0.5637693750796808 1.0 0.8133252030390948 15 Q9HAV4,Q06787,Q01085,P51114,Q08211 5 +Fatty acid beta oxidation 0.3010594655894193 0.5764363572112978 0.5643202757447423 1.0 0.8133252030390948 39 Q2T9J0,P23786,O14678,O43808,O14975,Q709F0,O14734,Q9BWD1,P28288,Q16134,P35610,O15254,Q15067 13 +Negative regulation of blood circulation 0.470149436025606 0.5736067398277038 0.5662339499001252 1.0 0.8142948015000266 3 P16615 1 +Atp biosynthetic process 0.3599492259986978 0.5731890087158876 0.566516725608567 1.0 0.8144427155257289 20 P00403,O75964 2 +Positive regulation of protein kinase b signaling 0.3800598496235012 0.5728393840502958 0.5667534499160247 1.0 0.8144427155257289 17 Q13641,Q969H8,Q9BZF1,Q86UE4,Q07021,Q9NQC3,P07900 7 +Positive regulation of cell growth 0.2830008744009567 0.5727778761358094 0.5667951006770875 1.0 0.8144427155257289 44 Q15418,O95684,O00560,P61586,Q96PU5,Q7L576,Q7Z4V5,Q9BSK2,Q96K76 9 +Negative regulation of cellular response to growth factor stimulus 0.4114522728987295 0.5727215194370842 0.5668332645239262 1.0 0.8144427155257289 13 O94813,P46934,O14936,Q8N0X7,O14964,P23634 6 +Endocytosis 0.2596669440676378 0.569871376437881 0.5687649400447903 1.0 0.8166817366682525 131 O15260,Q4KMQ2,Q5VW38,P46934,Q8WTV0,O00560,Q06787,P05067,P57105,O15118,Q96PU5,Q9NX40,P50897,Q14108,Q14457 15 +Neuron differentiation 0.2506742326001338 0.5671360443880357 0.5706217557573439 1.0 0.818464408061552 242 P30536,Q8WUJ1,Q13641,O00264,P35613,Q9UQB8,P50897,Q99707,O14949,P04062,Q14457,Q32P28,P33176,Q13277,P46108,Q14108,P42892,Q06787,P00374,P05067,Q9Y2A7,P61586,Q9NZJ7,Q96PU5,P08670,P54802,Q9NQX7,P46934,Q9NQC3,Q9HCE1,O75503,Q96JB5,Q9NR77,Q96G23 34 +Endosomal vesicle fusion 0.468631456084048 0.5671237728794479 0.5706300924842427 1.0 0.818464408061552 3 Q8WUH2,Q9P2R3 2 +Sulfur amino acid metabolic process 0.4102284626551841 0.5658675691102901 0.5714838092651786 1.0 0.8191400290945342 13 Q13126 1 +Regulation of receptor signaling pathway via stat 0.4393646949660892 0.5655596850550364 0.5716931401034944 1.0 0.8191400290945342 9 Q9H490,Q9NX40,P30153 3 +Regulation of retrograde transport endosome to golgi 0.4203617269544978 0.5652569239144334 0.5718990234129115 1.0 0.8192100833083443 2 Q93009 1 +Protein targeting to membrane 0.308146332574425 0.563246348559148 0.5732671461093677 1.0 0.8200713575887465 36 P46379,O60725,P43307,O00560,Q9NQG6,Q15629,Q9UGP8 7 +Endoplasmic reticulum to cytosol transport 0.4096655188786643 0.562720763953433 0.5736250428729575 1.0 0.8200713575887465 13 Q8TCT9,Q9UBV2,Q9BUN8,P14625,Q13438 5 +Odontogenesis 0.4248955966497059 0.562262565909372 0.5739371391455086 1.0 0.8202401162714626 11 P61586,Q07812,Q13547,P35613,Q6P4Q7,O75592 6 +Attachment of gpi anchor to protein 0.5068684049164418 0.5621804447781494 0.5739930834987133 1.0 0.8202401162714626 5 O43292 1 +Vacuolar localization 0.3608117450427208 0.5619905924846856 0.5741224287179703 1.0 0.8202463264200567 19 Q6IAA8,P33176,Q99584,Q9UBN7,P09601 5 +Fatty acid beta oxidation using acyl coa oxidase 0.4706669907106239 0.5591828684256501 0.5760369237417176 1.0 0.8226112038836386 7 O15254,Q15067 2 +Lactation 0.4242356235646716 0.5588036050729962 0.5762957618364917 1.0 0.8226349334720597 11 P00403 1 +Cellular response to virus 0.3456216802331469 0.5582410064121504 0.5766798229044299 1.0 0.8228251789299563 24 Q99623,Q06787,P07900,Q9NUD5,O43657 5 +Glucose import 0.430951804346189 0.5570068715925675 0.5775227342841331 1.0 0.8238194466260821 10 P52789,Q9BZF1,P11166,Q99523,Q16625 5 +Regulation of heart contraction 0.3246229179788854 0.5537798660133221 0.5797295091042944 1.0 0.8256926563286545 29 O75844,P20020,P78310,Q9HD47,Q99959,P16615,P10253 7 +Regulation of lipoprotein particle clearance 0.4945542519513829 0.5533317935716346 0.5800362340895917 1.0 0.8256926563286545 6 P61978 1 +Development of primary sexual characteristics 0.3131059946833495 0.552410071694123 0.5806674317200282 1.0 0.8258332460836575 33 O75874,O15360,Q13315,O95470,Q8TAF3,P49321 6 +Regulation of isomerase activity 0.4649008883966138 0.5512779988687829 0.581443118093516 1.0 0.8262014695646341 3 Q00839 1 +Regulation of dna topoisomerase atp hydrolyzing activity 0.4649008883966138 0.5512779988687829 0.581443118093516 1.0 0.8262014695646341 3 Q00839 1 +Body fluid secretion 0.407580900522864 0.5511012816963448 0.5815642468636155 1.0 0.8262014695646341 13 P00403 1 +Negative regulation of immune response 0.3409657632773971 0.5503317820009601 0.5820918291457937 1.0 0.8265956015716877 25 P01889,P46108,P04439,P04083,P09601 5 +Hindbrain morphogenesis 0.4295971423049272 0.5501369193291541 0.5822254658277881 1.0 0.8265956015716877 10 P04062 1 +Chemokine c c motif ligand 5 production 0.4645462503647586 0.549778201108986 0.5824715119883395 1.0 0.8265956015716877 3 Q7Z434,O00571 2 +Histone phosphorylation 0.3285688731742768 0.5488126568795533 0.5831340234092133 1.0 0.8266773568646155 28 Q13315,O75844,P54646,Q06787 4 +Regulation of leukocyte differentiation 0.3235789510906739 0.5449670638882738 0.5857761702153101 1.0 0.8287456208339271 29 P42345,O96005,P61586,P01889,P04083 5 +Protein localization to cytoplasmic stress granule 0.4674410298153051 0.5448146940801809 0.5858809715099951 1.0 0.8287456208339271 7 P67809,Q08211,P31483 3 +Bile acid biosynthetic process 0.4284774645963104 0.5444739546030701 0.5861153666004864 1.0 0.828898499058705 10 O14975,Q96SU4,P22059,O14734 4 +Regulation of pattern recognition receptor signaling pathway 0.3529395537443918 0.5429853288040664 0.5871399038354213 1.0 0.8299896701783788 21 Q9NPR9,Q9NQC3,O43657 3 +Regulation of smooth muscle contraction 0.5017638983057491 0.5416484358023813 0.5880607180915471 1.0 0.830933340249081 5 P61586 1 +Phosphatidylserine metabolic process 0.4916032698381631 0.5410661038701591 0.588462020551012 1.0 0.8309933989736875 6 P48651,Q8NCC3 2 +Regulation of t cell differentiation 0.4055669906420497 0.5399269470391406 0.5892474133769992 1.0 0.8315358121677137 13 O96005,P61586,P04083 3 +Negative regulation of telomere maintenance 0.3980663565282764 0.5381503351914563 0.5904732644053552 1.0 0.8329074722759976 14 P09651,Q00839,P07910,Q13315,Q9H0A0,Q9NVN8 6 +Positive regulation of nuclear division 0.3978829129828692 0.5371043243906175 0.5911955538941167 1.0 0.8332906254876037 14 Q9UJX4,Q14674,O14965,Q13042,Q96MF7 5 +Stem cell proliferation 0.4127383715787927 0.537021384943366 0.5912528424672787 1.0 0.8332906254876037 12 P04062 1 +Regulation of receptor internalization 0.3977680919759112 0.5364498331283867 0.5916476985001289 1.0 0.8336680690482812 14 O00560,Q06787 2 +Regulation of dna damage response signal transduction by p53 class mediator 0.4121610588959525 0.533932692491348 0.5933881023858774 1.0 0.835582130441229 12 O75844,Q13535 2 +Regionalization 0.3266511434594312 0.5330624021618935 0.5939903843269194 1.0 0.8361380519051219 28 Q8N2A8,P62995,Q8IZP0,O14786,O14965,Q9Y366,Q9UK61,Q13315,Q9Y2W6,Q5T9L3 10 +Semaphorin plexin signaling pathway 0.4321061730518449 0.5299012551438559 0.5961803958897249 1.0 0.8382549298968021 9 P42892 1 +Regulation of body fluid levels 0.2815817891188206 0.5297148765509894 0.5963096319172791 1.0 0.8382570275580946 50 Q4KMQ2,P38435,Q13505,P00403,P04062 5 +Positive regulation of cell cell adhesion mediated by cadherin 0.459035982110744 0.5266258435622102 0.5984534416375027 1.0 0.8401355328160531 3 O75955 1 +Nephron development 0.3808122568036891 0.5264981253056741 0.598542154208328 1.0 0.8401355328160531 16 Q12769,P35610 2 +Positive regulation of locomotion 0.2599445903606283 0.5235723080682925 0.600576046289274 1.0 0.8417300332657445 91 P42345,Q4KMQ2,Q13641,Q9NQC3,O14786,Q8WTV0,O95684,O00560,Q13277,P05067,P61586,Q9UH99,Q13315,P46108,P04083,Q96HY6,P09601 17 +Positive regulation of mrna splicing via spliceosome 0.3800765339710857 0.5220490877945775 0.601636153196683 1.0 0.8424960386847277 16 Q14011,P98179,P62995,Q13595,Q15427,P38159 6 +Neurogenesis 0.2393908986820928 0.5210165638458228 0.6023552326739985 1.0 0.8426473868529701 300 P30536,Q8WUJ1,Q13641,O14786,O14965,Q92974,O00264,P35613,Q9UQB8,P50897,Q8NCG7,P04083,Q99707,O14949,Q9Y6M7,P04062,Q14457,O75306,Q15154,Q32P28,Q15022,Q16706,P33176,Q13277,P46108,Q7L576,Q96N66,Q14108,P42892,Q06787,P00374,P55209,P05067,Q9Y2A7,P61586,Q9NZJ7,O14744,Q96PU5,P08670,P54802,Q9NQX7,P42345,P46934,Q9NQC3,Q9HCE1,O75503,O94901,Q8NAT1,Q96JB5,Q9NR77,Q96G23 51 +Positive regulation of leukocyte mediated immunity 0.3369704940887607 0.5198151704054104 0.6031924047437995 1.0 0.8432357392264195 25 Q9H2U1,Q96QE3,P01889,O96028,P04439,Q9NUQ9,Q96FZ2 7 +Regulation of lipid catabolic process 0.4360561743558591 0.519525783136518 0.6033941378897612 1.0 0.8432974533713571 8 Q2T9J0,Q8WTV0,O75874 3 +Cardiac chamber morphogenesis 0.4017564024340162 0.518926148172073 0.6038122426033734 1.0 0.8432974533713571 13 O14786,Q99959,O96028 3 +Positive regulation of carbohydrate metabolic process 0.4860144941800074 0.518039556191015 0.6044306709080667 1.0 0.8432974533713571 6 P54646 1 +Positive regulation of mesenchymal cell proliferation 0.409859976662781 0.516804344554286 0.6052927469337233 1.0 0.8432974533713571 2 P35222 1 +Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 0.409859976662781 0.516804344554286 0.6052927469337233 1.0 0.8432974533713571 2 P35222 1 +Nephron tubule epithelial cell differentiation 0.409859976662781 0.516804344554286 0.6052927469337233 1.0 0.8432974533713571 2 P35222 1 +Regulation of epithelial cell differentiation involved in kidney development 0.409859976662781 0.516804344554286 0.6052927469337233 1.0 0.8432974533713571 2 P35222 1 +Mesenchymal to epithelial transition involved in metanephros morphogenesis 0.409859976662781 0.516804344554286 0.6052927469337233 1.0 0.8432974533713571 2 P35222 1 +Metanephros morphogenesis 0.409859976662781 0.516804344554286 0.6052927469337233 1.0 0.8432974533713571 2 P35222 1 +Renal vesicle development 0.409859976662781 0.516804344554286 0.6052927469337233 1.0 0.8432974533713571 2 P35222 1 +Metanephric nephron morphogenesis 0.409859976662781 0.516804344554286 0.6052927469337233 1.0 0.8432974533713571 2 P35222 1 +Metanephric renal vesicle morphogenesis 0.409859976662781 0.516804344554286 0.6052927469337233 1.0 0.8432974533713571 2 P35222 1 +Gamete generation 0.2596592514884402 0.5157290272251208 0.6060436781465475 1.0 0.8436281192778459 117 P46379,P62753,O14965,Q13315,O14777,Q96MU7,Q8TAF3,P30153,Q9Y5A9,Q8N2A8,Q12768,Q96GX5,Q9H2V7,Q01085,Q9Y2W6,Q8NB78,Q07666,Q15067,Q9H2U1,P51572,A0AVF1,Q96EP5,O15360,Q9H6S0,O95067,O95470,P41208,O75718,Q9BTX1,P42345,P78310,O94901,Q9UHJ3,P53350,Q9UHI6 35 +Actin filament based movement 0.3068852955266525 0.5126000828257467 0.608231095259959 1.0 0.8455575326315948 34 Q9HD47,Q99959,Q9UH99,P16615,Q9UM22,Q96PU5 6 +Positive regulation of ubiquitin protein transferase activity 0.4150588298424709 0.5112333575169639 0.6091876634692717 1.0 0.8460295127376425 11 Q92564,Q9BTE7,P53350 3 +Inositol lipid mediated signaling 0.3529675880341535 0.5090851697922257 0.6106925264267937 1.0 0.8470438297215431 19 Q10713,Q969H8,P46934,O95630,Q14457 5 +Genitalia morphogenesis 0.4081096849474951 0.5088565437618637 0.610852782115272 1.0 0.8470870575317868 2 P35222 1 +Platelet derived growth factor receptor signaling pathway 0.4069996121404498 0.5065062015508219 0.6125013372489279 1.0 0.8477575416207441 12 O95470 1 +Response to metal ion 0.2746859041253471 0.5053788652829061 0.613292760199347 1.0 0.8477832509854888 69 P30536,P46934,P54646,P05067,O15118,P35613,Q14103,O60888,Q96PU5,P09601,Q14457 11 +Demethylation 0.3606572405417234 0.5029473996143051 0.6150012545106167 1.0 0.8492504697177329 18 Q8NB78,Q16850,P16435 3 +Cellular response to retinoic acid 0.4323868935151782 0.502313529959239 0.6154469933794673 1.0 0.8493065895643194 8 Q13315,Q9P0J0 2 +Positive regulation of response to endoplasmic reticulum stress 0.4570527348922196 0.4992226785250427 0.617622519652766 1.0 0.8508251727167478 7 P46379,P57088 2 +Nephron epithelium development 0.4126888394517145 0.4991162086353617 0.6176975194792116 1.0 0.8508251727167478 11 P35610 1 +Multicellular organism growth 0.3110955646821066 0.4975533929079592 0.6187988609236681 1.0 0.8516159993401955 31 O75844,P42345,P05067,O95470,Q8TAF3 5 +Natural killer cell activation 0.4189218849104856 0.4967385824462648 0.619373410899623 1.0 0.8516159993401955 10 P46379,Q96L92,Q5HYI8 3 +Microtubule anchoring 0.4122165889021137 0.4967104050385904 0.619393283890084 1.0 0.8516159993401955 11 Q8TD16,Q15154,O95684 3 +Nucleoside bisphosphate biosynthetic process 0.3175243833643658 0.4943180550060951 0.6210815760325774 1.0 0.8523050184865706 29 Q8WVC6,Q53GQ0,Q15118,P50897,Q8TB61,P35610 6 +Tetrahydrofolate metabolic process 0.4112827337890753 0.4919616716029737 0.6227464392980036 1.0 0.8533017612598662 11 P34896,P00374 2 +Motor neuron axon guidance 0.4792166947497407 0.4904093514031261 0.6238442607113526 1.0 0.8537926923924388 6 O14786,O94813 2 +Regulation of neurotransmitter transport 0.3747943462204803 0.4903512109017766 0.6238853947000524 1.0 0.8537926923924388 16 O14936,P05771,Q06787,O75955,P16615,Q4J6C6 6 +Heart process 0.3023384331455644 0.4887462521732211 0.6250213541536762 1.0 0.8547837756873979 35 O75844,P20020,P42345,P78310,Q9HD47,Q99959,P16615,Q96PU5,P10253 9 +Response to oxygen containing compound 0.236922441960863 0.4883306029298369 0.6253156882440352 1.0 0.8547837756873979 305 Q99623,P30536,P20020,Q15120,Q8TB36,Q86UE4,Q92974,Q13315,P35613,Q14103,Q9UQB8,P04083,Q15907,Q99707,Q99720,Q9P0J0,P04062,Q14457,O95831,P43490,Q8WTV0,Q99729,P16278,P08574,P14625,Q13151,Q9Y5Z4,O15228,P46108,Q7L576,P09601,P22059,Q9BSK2,P49321,Q15043,Q9BZF1,P54646,P00374,P05067,P61586,O14744,Q9BRK5,Q9H7B4,P08670,P23378,O43865,P42345,P16435,Q13126,Q8TBX8,P27544,Q8N5M9 52 +Mitochondrial atp synthesis coupled proton transport 0.4171935177861469 0.4882240129291501 0.6253911775487957 1.0 0.8547837756873979 10 O75964 1 +Protein deglycosylation 0.4775941191097627 0.483878478678339 0.6284721147857621 1.0 0.8569059946456155 6 O60502,O60476 2 +Sensory perception of mechanical stimulus 0.3491495250884658 0.4837223691714133 0.6285829156916254 1.0 0.8569059946456155 19 Q9Y5J9,Q9Y6M9,O76024,Q14108,Q9Y5L4 5 +Receptor localization to synapse 0.4096350856620366 0.4836115855615409 0.6286615509841131 1.0 0.8569059946456155 11 P33176,Q14168,P57105 3 +Regulation of apoptotic process involved in development 0.402275379229873 0.4826455008874293 0.6293474658430154 1.0 0.8569823592005641 2 Q07812 1 +Cellular defense response 0.4864964481928789 0.4815330420565835 0.6301377018013608 1.0 0.8578762653984501 5 Q14457 1 +Regulation of b cell differentiation 0.401691948658111 0.4800489378511405 0.63119259544525 1.0 0.8585306563731541 2 Q5JVF3 1 +Mitochondrial acetyl coa biosynthetic process from pyruvate 0.4860878119480428 0.4799525788782292 0.631261112918855 1.0 0.8585306563731541 5 P11177 1 +Replicative senescence 0.4860836543839484 0.4799365068920138 0.6312725414508487 1.0 0.8585306563731541 5 Q13535 1 +Labyrinthine layer morphogenesis 0.4476218266705754 0.4796264510973538 0.6314930344125238 1.0 0.8586525677196397 3 P62993,Q15363 2 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.2553710516598218 0.47888641803716 0.6320194337523488 1.0 0.8591845865672817 84 O14786,P27695,Q9Y5X3,Q9UQB8,O14964,P43490,Q8IZP0,P46108,Q9HCD5,Q7L576,Q92922,Q15043,P42574,Q9BZF1,P05771,Q9Y4G8,Q99523,O95470,P04049,P46934,Q9NQC3,Q93034,Q8TBX8,Q8NEM2 24 +Regulation of filopodium assembly 0.3874118145069029 0.4781785869151065 0.6325231018377258 1.0 0.859203210012423 14 P51116,P51114 2 +Positive regulation of leukocyte proliferation 0.4014086792390834 0.4771987418665666 0.6332206069421673 1.0 0.859754525709601 12 P30825,P04439,P04083 3 +Positive regulation of oligodendrocyte differentiation 0.4850510357003675 0.4759497211531001 0.6341101982851374 1.0 0.860428271535788 5 P42345 1 +Regulation of t cell apoptotic process 0.4464546250364908 0.4748977923109269 0.6348598250890665 1.0 0.8610220940019996 3 P17931,P78540 2 +Positive regulation of execution phase of apoptosis 0.446454625036483 0.4748977923108951 0.6348598250890891 1.0 0.8610220940019996 3 Q8IXJ6,P63167 2 +Amyloid beta formation 0.4076608581382075 0.4736549977045751 0.6357459495232427 1.0 0.861085695933651 11 P42574,Q92542,O95197,Q9NQC3,P27695 5 +Fatty acyl coa metabolic process 0.3794117057380951 0.473429298547508 0.6359069311939154 1.0 0.861085695933651 15 A8MXV4,Q53GQ0,P50897,Q96K12,Q9NZ01 5 +Cellular response to muramyl dipeptide 0.445184822155048 0.4697705356427456 0.6385189673636591 1.0 0.8630198689681423 3 P08670 1 +Calcium mediated signaling 0.3552455121583665 0.4684514331171945 0.6394617944614109 1.0 0.8637604560016011 18 O75844,P42345,P16615 3 +Negative regulation of epithelial cell migration 0.3995325347389192 0.4674628322827124 0.6401687779571192 1.0 0.8642588739350875 12 P61586,O94813,P57105 3 +Cellular response to insulin stimulus 0.2766335843396604 0.4669947471928961 0.6405036362260477 1.0 0.8642588739350875 53 P20020,P43490,Q8TBX8,Q9UQB8,Q7L576,Q9BSK2,Q15043 7 +Response to hydrogen peroxide 0.3050346717797779 0.4654122681741935 0.6416362503296436 1.0 0.8648633961178034 32 P04083,Q99720,P09601,Q14457,O95831 5 +Developmental process involved in reproduction 0.2539631736139346 0.4642889476325744 0.6424407414345001 1.0 0.8656460257275544 151 Q99623,P46379,O75874,O14965,Q13315,P35613,P04083,Q15392,Q8TAF3,Q8N2A8,Q12768,P07602,Q01085,Q9Y2W6,P49770,Q07666,P49321,Q15067,Q9H2U1,A0AVF1,O15360,Q9NZJ7,O95470,P41208,O75718,Q9BTX1,P42345,O94901,Q9UHJ3 29 +Negative regulation of glucose import 0.3976079346557831 0.4620026400743383 0.6440794272020522 1.0 0.8666084070739936 2 O00186 1 +Heterotypic cell cell adhesion 0.4050487682315762 0.4605649624562986 0.645110754130674 1.0 0.8671070808286527 11 Q99959,P78310 2 +Extracellular matrix assembly 0.4477728133842488 0.4594443436766328 0.6459151107757721 1.0 0.8678005849907845 7 Q96AY3 1 +Secretion 0.253209120446818 0.4576413104137804 0.6472101593078139 1.0 0.8686833842049242 155 Q9NP80,Q9UBV2,O00560,P16615,P53985,P50897,P04083,Q15907,P00403,Q32P28,Q13277,Q9UPT5,Q13505,P09601,P22059,Q5T9L3,Q96KC8,Q06787,Q9BRK5,Q16850,Q9H7Z7,Q96PC5,Q4J6C6,Q8N5M9 24 +Striated muscle contraction 0.3250221121839619 0.456757886421026 0.647845078759806 1.0 0.8690023317297315 26 P42345,Q9HD47,Q99959,P16615,Q96PU5,P10253 6 +Regulation of calcium ion dependent exocytosis 0.4788337388784275 0.4521622363148908 0.6511521110641325 1.0 0.8723433572064204 5 P16615 1 +Positive regulation of phosphatidylinositol 3 kinase signaling 0.4688127100766067 0.4489872958705199 0.653440821149089 1.0 0.874011266648902 6 P46934 1 +Positive regulation of wnt signaling pathway 0.3391951812367137 0.4480599579867504 0.6541099254057845 1.0 0.874011266648902 21 Q96K76,Q9H2V7,Q5T9L3 3 +Platelet derived growth factor receptor beta signaling pathway 0.4862813776999471 0.4476843148245965 0.6543810432493091 1.0 0.8741599863176807 4 Q07954,O75146,O00291 3 +Negative regulation of b cell apoptotic process 0.4391596148234788 0.4456907387751054 0.6558206553133772 1.0 0.8752278096738623 3 P14174,Q96GD4 2 +Negative regulation of mitochondrial fusion 0.4382842135979139 0.4422272890040037 0.6583247407659241 1.0 0.8778296509448202 3 P02786,Q7Z6Z7 2 +Regulation of neuron projection development 0.2644528855603378 0.4412776040513966 0.659012037623413 1.0 0.8778296509448202 73 Q9NQX7,Q32P28,Q9NQC3,P46934,P61586,P46108,Q9UQB8,P08670,Q96PU5,Q9NR77,Q14108,Q96G23 12 +Regulation of dendrite morphogenesis 0.373696300622336 0.4410201449116593 0.659198413133 1.0 0.8778296509448202 15 Q9UQB8,P46934 2 +Respiratory gaseous exchange by respiratory system 0.4007356242254902 0.439166114472873 0.6605411761383668 1.0 0.8786402875522363 11 P10253,Q7KZN9,O60476 3 +Response to bacterium 0.2751647197792914 0.4389063645867476 0.6607293848333518 1.0 0.8786402875522363 63 P30536,Q86UE4,Q8WTV0,Q13151,Q9BTY2,P61586,P01889,P08670,Q9UQB8,P04439,Q9NZ08 11 +Vesicle cytoskeletal trafficking 0.3351354862040805 0.438005786600317 0.6613820886932009 1.0 0.8788325412127826 22 P42858,P27695,P33176,O94832,O43707,Q9Y2T2 6 +Activation of cysteine type endopeptidase activity 0.3920653442240408 0.4378870853940222 0.6614681379228793 1.0 0.8788325412127826 2 Q96F07 1 +Apoptotic mitochondrial changes 0.300254984335511 0.4374302994836466 0.6617993142316532 1.0 0.8789519670635638 33 Q96A26,O14737,P45880 3 +Phosphatidylinositol phosphate biosynthetic process 0.3865466778682165 0.437153225554629 0.6620002290370224 1.0 0.8789519670635638 13 Q13315,Q8TBX8,Q14457 3 +Regulation of phosphatidylcholine metabolic process 0.4833333886940313 0.4369612296178429 0.662139465456137 1.0 0.8789519670635638 4 Q8WTV0 1 +Negative regulation of blood vessel endothelial cell migration 0.4656597667224435 0.4366548188762312 0.662361700263536 1.0 0.8789519670635638 6 P61586 1 +Cellular response to oxygen containing compound 0.2450565398448356 0.4350277409001276 0.6635422916651943 1.0 0.8796291955367687 225 Q99623,P30536,P20020,Q15120,Q8TB36,Q86UE4,Q92974,Q13315,Q14103,Q9UQB8,P04083,Q15907,Q99707,Q99720,Q9P0J0,Q14457,O95831,P43490,Q8WTV0,Q99729,P14625,P46108,Q7L576,P22059,Q9BSK2,Q15043,Q9BZF1,P54646,P00374,P05067,P61586,O14744,Q9H7B4,P08670,O43865,P42345,P16435,Q8TBX8,P27544,Q8N5M9 40 +Cytokine production involved in immune response 0.3860308734194791 0.4344427465686582 0.6639669621027664 1.0 0.8796590360020903 13 P09601 1 +Regulation of b cell apoptotic process 0.4823849374956527 0.4335295416849105 0.6646301092420468 1.0 0.880193909787842 4 Q96GD4,Q07812 2 +Long chain fatty acid metabolic process 0.3219471086195338 0.4335173627765113 0.6646389550440044 1.0 0.880193909787842 26 P23786,Q9NP80,O14975,O14734,P07099,P28288,Q8NCG7,Q9H7Z7 8 +Amyloid beta metabolic process 0.3790278157191884 0.432209285845617 0.6655893110015882 1.0 0.8810968446222357 14 P42574,Q92542,O95197,Q9NQC3,P27695,Q14457 6 +Positive regulation of lymphocyte mediated immunity 0.3411614052308921 0.4315780881932989 0.666048086786893 1.0 0.8811708761079823 19 Q96QE3,P01889,O96028,P04439,Q9NUQ9,Q96FZ2 6 +Regulation of atp dependent activity 0.3033719995373017 0.431337935523197 0.6662226706965892 1.0 0.8812241816389879 31 Q9UBS4,Q00839,Q04837,Q8NFQ8,Q15070,Q08211,Q96GC9 7 +Negative regulation of oligodendrocyte differentiation 0.3897316219369932 0.4278679194069881 0.6687472845936666 1.0 0.8826359666158883 2 P35222 1 +Negative regulation of glial cell differentiation 0.3897316219369932 0.4278679194069881 0.6687472845936666 1.0 0.8826359666158883 2 P35222 1 +Negative regulation of osteoclast differentiation 0.3897316219369932 0.4278679194069881 0.6687472845936666 1.0 0.8826359666158883 2 P35222 1 +Positive regulation of epithelial cell migration 0.2989303918296195 0.4258401874579864 0.6702243011571025 1.0 0.8828109005167349 33 P42345,Q9NQC3,O14786,Q8WTV0,Q9UBN7,P04083,P09601 7 +Regulation of lymphocyte apoptotic process 0.4396728016359916 0.4255293702771617 0.6704508158415692 1.0 0.8828109005167349 7 Q96GD4,P17931,P04637,Q07812,P78540,P14174 6 +Neurotransmitter transport 0.3275493164623398 0.4254391946285758 0.6705165388868344 1.0 0.8828109005167349 24 Q4J6C6,Q06787,P50897,P16615 4 +Positive regulation of neuron projection development 0.3045922900168753 0.4242765663247706 0.6713641271609974 1.0 0.8832709287834384 30 Q32P28,Q14108 2 +Adaptation of signaling pathway 0.3888564760793506 0.4241319125995246 0.6714696130101703 1.0 0.8832709287834384 2 P50570 1 +G protein coupled receptor internalization 0.3888564760793506 0.4241319125995246 0.6714696130101703 1.0 0.8832709287834384 2 P50570 1 +Artery morphogenesis 0.4145519940253698 0.4210141659609724 0.6737447376498027 1.0 0.8852849356143383 8 O14786,Q96AY3 2 +Epithelial structure maintenance 0.4324679491786012 0.4194507462881236 0.674886743718146 1.0 0.8859133014756398 3 P78310 1 +Protein import into peroxisome matrix 0.3876896149358224 0.4191687942225601 0.6750927765180867 1.0 0.8859133014756398 2 O75381 1 +Negative regulation of wnt signaling pathway 0.3473222300105308 0.4189549191077305 0.6752490792154751 1.0 0.8859133014756398 18 Q13641,P48729,Q6DKJ4 3 +Positive regulation of dna dependent dna replication 0.4691970802919752 0.416064192050641 0.6773630314507182 1.0 0.8871639100087508 5 Q9UJZ1,P24941,Q14249,Q04837 4 +Positive regulation of response to dna damage stimulus 0.2714136577468034 0.4158566684583099 0.6775148888833198 1.0 0.8871639100087508 50 P51116,Q06787,P35637,Q13315,Q13535,P51114,Q8TAF3 7 +Water homeostasis 0.4018335509523869 0.4143467026872451 0.6786202154717507 1.0 0.8879071705665562 10 Q96PU5,P04062 2 +Regulation of b cell mediated immunity 0.3886057955017765 0.4118259605071598 0.6804669918910713 1.0 0.8894869324281294 12 Q96FZ2,O96028,Q96FV9 3 +Pyridine containing compound metabolic process 0.4069806175993695 0.4113974534890559 0.68078112086876 1.0 0.8896689102059663 9 P43490 1 +Regulation of small molecule metabolic process 0.271505717916426 0.4110812698146486 0.6810129436093522 1.0 0.8896689102059663 52 O75844,Q2T9J0,P16435,Q15118,P54646,P05067,P04083,Q9BYT8,P00403 9 +Muscle cell migration 0.3745296052594113 0.4080382506485945 0.6832455928863832 1.0 0.8910301374565962 14 O94813,O14786,P61586,P46108,P04083 5 +Vascular associated smooth muscle contraction 0.4751746371569826 0.4077403946179293 0.683464277822414 1.0 0.8910301374565962 4 P61586 1 +Biological process involved in intraspecies interaction between organisms 0.4580763247796466 0.4074406778731427 0.6836843556985617 1.0 0.8910301374565962 6 Q96RL7 1 +Cellular response to gamma radiation 0.394100419262109 0.4068001017480023 0.6841548120076639 1.0 0.8912956091528277 11 O75844,Q13535 2 +Regulation of alpha beta t cell activation 0.3873388376014475 0.4054993547643706 0.68511049261915 1.0 0.8912956091528277 12 P04439,P04083 2 +Synaptic signaling 0.2522203374327387 0.4051537930938619 0.6853644673941637 1.0 0.8914492834569875 92 Q15418,Q13641,P52429,P33176,O00560,Q06787,Q13277,P05067,P57105,P16615,Q14168,Q4J6C6,Q9UQB8,P52294,P50897,Q9NR77 16 +Axon development 0.2492820319190156 0.4036190153294896 0.6864929004283353 1.0 0.8923863733381014 81 P30536,P42892,Q9NQC3,P33176,P00374,P05067,O00264,P35613,Q9UQB8,Q99707,Q96G23 11 +Aspartate family amino acid biosynthetic process 0.3798126137038085 0.4021212820521422 0.6875947709473187 1.0 0.8927575953613583 13 Q99707,Q13126 2 +Torc1 signaling 0.4337331491056789 0.40117477650798 0.6882914500274551 1.0 0.8933086422231329 7 P42345 1 +Kidney epithelium development 0.3795923485840309 0.4009887327481181 0.6884284193904868 1.0 0.8933097267234278 13 Q9Y5V3,P35610 2 +Germ cell development 0.2738722756491975 0.3997530346074293 0.6893384257219415 1.0 0.893783590118036 42 P42345,Q8N2A8,Q12768,P62753,A0AVF1,O14965,Q9H6S0,Q01085,Q13315,Q9Y2W6,Q96MU7,Q9UHI6,P30153 13 +Regulation of isotype switching 0.3924543310177589 0.3988795042311507 0.6899819918490917 1.0 0.894441294056448 11 Q96FZ2,O96028,Q96FV9 3 +Negative regulation of receptor mediated endocytosis 0.3859684349075682 0.3986868874329614 0.6901239308424416 1.0 0.8944485945463366 12 O00560,P05067 2 +Regulation of lymphocyte differentiation 0.3515598000340741 0.3978990992361906 0.6907045640465366 1.0 0.8947067603999214 17 O96005,P61586,P04083 3 +T cell migration 0.4087047039940248 0.3953009617965238 0.6926207896834489 1.0 0.8956424294710714 8 P46108,P61586,P05067 3 +Mannosylation 0.4033986079812741 0.3952167646435589 0.6926829212992514 1.0 0.8956424294710714 9 O60762,Q6ZXV5,Q9BT22,Q8NAT1,O43505,Q2TAA5 6 +Establishment of tissue polarity 0.4085837202349982 0.3947742593298193 0.6930094932799746 1.0 0.8956850901691354 8 Q8TAA9,P61586 2 +Wound healing 0.2714661713372612 0.3946492514872687 0.6931017602698095 1.0 0.8956850901691354 64 P42345,Q4KMQ2,P52429,Q8WTV0,P38435,P61586,P42785,P04083,Q16625,P09601 10 +Receptor recycling 0.4320794799303519 0.3944755800589789 0.6932299529014343 1.0 0.8956850901691354 7 P42892 1 +Negative regulation of intracellular estrogen receptor signaling pathway 0.4713928500257097 0.3944323040279671 0.6932618977398719 1.0 0.8956850901691354 4 Q99623 1 +Regulation of microtubule based movement 0.4542320633687019 0.3928833423879834 0.6944056452020497 1.0 0.896809652394381 6 P78318,P11279,Q9UBN7 3 +Regulation of myelination 0.3971529526269721 0.3925296003919014 0.6946669447073748 1.0 0.8969138687742952 10 Q7L576,P42345 2 +Positive regulation of nervous system development 0.2668554592022963 0.3912899581579601 0.6955829206048869 1.0 0.8970635905962562 45 P30536,P42345,Q13641,Q16706,O14786,O14744,P55209,Q9UQB8,Q7L576 9 +Filopodium assembly 0.3646757014519581 0.3910579163633558 0.695754426497531 1.0 0.8970635905962562 15 P51116,P51114 2 +Unsaturated fatty acid biosynthetic process 0.3843055233951296 0.3904638571648254 0.6961935762930818 1.0 0.8970635905962562 12 Q9H7Z7,Q9NP80,O95864,P04083,Q8NCG7 5 +Mesonephros development 0.4535708999249609 0.3903973581688104 0.6962427410708218 1.0 0.8970635905962562 6 Q9Y5V3 1 +Glial cell differentiation 0.2759717570213419 0.3887715429379127 0.6974451535072568 1.0 0.8975331910563481 41 P42345,Q15022,P05067,O14744,P61586,P49770,P08670,P04062 8 +Positive regulation of immunoglobulin production 0.3839008923996233 0.3884702880349303 0.6976680376943798 1.0 0.8975331910563481 12 Q99623,Q96FZ2,O96028 3 +Regulation of response to oxidative stress 0.3248784672840584 0.3862491459926928 0.6993121591869678 1.0 0.8980010738897338 23 Q9NP80,P23246,P00374,Q9Y5Z4,Q07820 5 +Positive regulation of vascular associated smooth muscle cell proliferation 0.4236941931718836 0.3859013525613363 0.6995697288731624 1.0 0.8980010738897338 3 P26358,P04899 2 +Negative regulation of adenylate cyclase activity 0.4236941931718794 0.3859013525613204 0.6995697288731741 1.0 0.8980010738897338 3 P04899,Q99996 2 +Negative regulation of lyase activity 0.4236941931718794 0.3859013525613204 0.6995697288731741 1.0 0.8980010738897338 3 P04899,Q99996 2 +Peptide transport 0.2890695450758577 0.3859003383988907 0.6995704799945626 1.0 0.8980010738897338 36 P53985,Q03519,P04083,Q15907,Q03518 5 +Mitotic dna integrity checkpoint signaling 0.2942795597122772 0.3855892475831525 0.6998008977530996 1.0 0.8981211599952748 33 Q92547,Q6NUQ1,Q9Y619,Q13315,P78527,P53350,Q96JB5 7 +Positive regulation of interleukin 6 production 0.4011478747618772 0.3851512014956995 0.7001253951982429 1.0 0.8981862841233372 9 P05067,Q92974 2 +Nucleosome assembly 0.2907483493680438 0.3840496471276376 0.7009416506701744 1.0 0.898706352422369 35 Q99733,Q9H7B4,P55209 3 +Positive regulation of lipopolysaccharide mediated signaling pathway 0.3792298716452789 0.3838298575645641 0.7011045568312366 1.0 0.898739617489075 2 P14174 1 +Dna replication dependent chromatin organization 0.4290230889435204 0.3821901769428834 0.7023203074692614 1.0 0.899770764860073 7 O14929 1 +Eating behavior 0.3786464410735122 0.3814357023036964 0.7028799732198416 1.0 0.9001362966956675 2 P50416 1 +Response to inorganic substance 0.2512025186890173 0.3801508112271506 0.7038334700158044 1.0 0.9008118933739196 118 P30536,P46934,P54646,P00374,Q06787,P05067,O15118,P35613,Q14103,O60888,Q96PU5,P04083,Q99707,Q99720,P09601,Q14457 16 +Regulation of protein exit from endoplasmic reticulum 0.4284710845284539 0.3799848954157514 0.7039566274339317 1.0 0.9008118933739196 7 Q13438,Q92544 2 +Regulation of dna helicase activity 0.4216515903122394 0.3782370234173852 0.7052545241268127 1.0 0.9019853633170284 3 P49736,Q04837 2 +Signal transduction by p53 class mediator 0.2679458725955359 0.3780002353698272 0.705430419126321 1.0 0.9019853633170284 50 P46379,O75844,P42345,P61978,O14965,O14744,Q13315,Q13535,P62841,Q96JB5 10 +Ribonucleoprotein complex disassembly 0.4584023403722218 0.3768302301362324 0.7062997736160479 1.0 0.90257821119153 5 P33176 1 +Atp synthesis coupled proton transport 0.387706429605871 0.3762880354062546 0.7067027731735442 1.0 0.9027415996816812 11 O75964 1 +Signal release 0.2693275689807035 0.3745819508178357 0.707971398452758 1.0 0.9037477995686184 58 O14936,Q13277,Q06787,P16615,P53985,Q4J6C6,P04083,Q15907,P50897,Q16836,P22059,Q8N5M9,Q5T9L3 13 +Lipopolysaccharide mediated signaling pathway 0.398659734181828 0.3741176148815555 0.708316813956325 1.0 0.9037477995686184 9 Q8WTV0 1 +Regulation of t cell migration 0.4567574767570503 0.3709702408994595 0.7106596970246521 1.0 0.905371792516479 5 P05067,P61586 2 +Production of molecular mediator of immune response 0.2796659870474117 0.3673122533687475 0.7133861150711951 1.0 0.9073578351395282 39 Q99623,Q9H2U1,Q9UQ84,O96028,P04439,Q96FV9,Q96FZ2,P09601 8 +Lymphocyte homeostasis 0.4019449157307566 0.3662165162849913 0.7142035187720521 1.0 0.9074982415177272 8 P42574,O95067,P49327,P62753 4 +Regulation of lipid localization 0.3218899083082149 0.3659035476595422 0.714437049021728 1.0 0.9074982415177272 23 P30536,O15260 2 +Branching involved in blood vessel morphogenesis 0.4545985401459899 0.3633281275093066 0.7163597841901004 1.0 0.908929299917343 5 O14786,P35222,Q96T37,Q14344 4 +Cotranslational protein targeting to membrane 0.3659420893265656 0.3629386243733715 0.7166507330853256 1.0 0.9090783124890598 14 P43307 1 +Smooth muscle cell proliferation 0.3280175804282242 0.3603162004354892 0.718610685633396 1.0 0.910332687090028 20 P09601,P61586,Q9Y2S7 3 +Regulation of biological process involved in symbiotic interaction 0.3897797664445645 0.3588879892246441 0.7196788851108995 1.0 0.9108513694546572 10 Q9BTY2,Q9UPT5 2 +Regulation of alpha beta t cell differentiation 0.4000296628817973 0.3581069393246613 0.7202632861450569 1.0 0.9108513694546572 8 P04083 1 +Histone h4 acetylation 0.3082101861811435 0.3576724052969791 0.7205884861483938 1.0 0.9108513694546572 27 O75844,Q86UY6 2 +Release of cytochrome c from mitochondria 0.3584569664482744 0.3575423686779256 0.7206858138080738 1.0 0.9108513694546572 15 Q96A26,O14737 2 +Positive regulation of jnk cascade 0.3946538044040528 0.3565661041919724 0.7214166565346183 1.0 0.911599480104018 9 O00560,P05067 2 +Response to peptide 0.2502800496793021 0.3560932837953552 0.7217707067728689 1.0 0.9116957416445748 103 P20020,Q92974,Q9UNS1,P35613,Q9UQB8,P04083,P43490,P11166,P08574,P49770,P78527,P46108,Q7L576,Q9BSK2,Q15043,Q9BZF1,P05067,P08670,Q99523,O43865,P42345,P16435,Q8TBX8,Q16836 24 +Regulation of transport 0.2258137790809973 0.3553408479426441 0.7223342573352975 1.0 0.91190770831182 344 Q99623,P30536,P20020,Q9P2W9,P61978,P52789,O14786,P21796,O00560,P11279,P16615,P53985,Q9HCU5,P50897,P04083,Q15907,Q8IZ07,Q9ULX6,Q9BWF3,P35658,O75844,P08183,Q32P28,Q4KMQ2,Q15154,O14737,Q8WTV0,P33176,Q7Z3B4,P00367,P50402,Q7L576,P09601,P22059,Q07666,Q96GC9,Q5T9L3,Q96KC8,P42858,Q6NUQ1,P55011,Q9BZF1,P55786,Q99959,Q06787,P05067,P61586,Q9H223,Q16850,Q96PU5,Q9C0E2,Q16625,O43865,Q13438,O15260,O76024,Q9Y282,P46934,Q9HD47,P05023,O14936,P57105,Q9NQG6,Q14BN4,Q4J6C6,Q08211,Q08431,Q92544,O95487,Q16836,Q8N5M9 71 +Regulation of lymphocyte activation 0.2671752278995023 0.3548435864882612 0.7227067730968875 1.0 0.9121204477882846 56 Q96J02,P11279,O96005,O15360,P61586,Q13315,Q96QE3,P30825,O96028,P04083,Q96FV9,Q9NUQ9,Q96FZ2,P04439 14 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.3440112890777559 0.3541975051469395 0.723190873163555 1.0 0.9121204477882846 17 P46379,O60313,O95881,O95831 4 +Cellular response to molecule of bacterial origin 0.2938620029704069 0.3522511817635235 0.7246498960258974 1.0 0.9123470103073558 31 P30536,Q8WTV0,P61586,Q86UE4 4 +Sarcoplasmic reticulum calcium ion transport 0.3879532217252819 0.350697865332274 0.7258150271891117 1.0 0.9128554584667632 10 O75844 1 +Regulation of cyclin dependent protein kinase activity 0.3264764860474443 0.3506227550062076 0.7258713830006163 1.0 0.9128554584667632 20 P42574,Q16543,O95067,Q96JB5,P53350 5 +Second messenger mediated signaling 0.3168460606881854 0.350414657422791 0.7260275278479178 1.0 0.9128554584667632 24 O75844,P42858,P51572,P42345,P16615,Q9Y4G8,P30153,P23634 8 +G protein coupled receptor signaling pathway 0.2661492657295851 0.3497640016834831 0.7265158171423232 1.0 0.9131194775115734 53 P52429,P07602,P42892,O14744,Q9NZJ7,Q86V85,P04083,Q99720,Q9BYT8,Q15043 10 +Positive regulation of neuron apoptotic process 0.369086315505046 0.3480179592064794 0.7278266960878033 1.0 0.9142417265942122 13 Q13315,P61586,Q07820,O95831 4 +Spliceosomal tri snrnp complex assembly 0.3752857558651427 0.3467311380284569 0.7287933149771759 1.0 0.915280714426838 12 Q13107,Q6P2Q9 2 +Regulation of cell activation 0.2621587029375651 0.3463801482849489 0.7290570421778735 1.0 0.9153514282532804 69 Q15418,Q96J02,P11279,O96005,O15360,P61586,Q13315,Q96QE3,P30825,O96028,P04083,Q96FV9,Q9NUQ9,Q96FZ2,P04439,P09601 16 +Coronary artery morphogenesis 0.4128600954741919 0.3459136740048002 0.7294075919439811 1.0 0.9153514282532804 3 O14786 1 +Positive regulation of protein binding 0.321290026116115 0.3450897039545712 0.7300269336170861 1.0 0.9157783862350066 22 O14786,Q9BUN8,P05067,Q9Y4G8,Q9Y2S7,Q96D46 6 +Monoubiquitinated protein deubiquitination 0.3806187859382799 0.3433006413384047 0.7313722983805944 1.0 0.9167650471773564 11 Q9Y6J9,Q99496,Q9BWJ5,Q96K76 4 +Alpha beta t cell proliferation 0.455819575364873 0.3413237151904003 0.7328598965876425 1.0 0.9177531758412424 4 P04439 1 +Cellular response to glucose starvation 0.3674859895832597 0.3401380153710311 0.733752594534647 1.0 0.918466841300259 13 P54646,Q14457 2 +Muscle cell proliferation 0.3057662837748154 0.3396373827913094 0.7341296224656901 1.0 0.918466841300259 27 P09601,P52294 2 +Protein ufmylation 0.4475643571002716 0.3388277304132064 0.7347395098060459 1.0 0.9190546441759956 5 Q96JB5 1 +Mitochondrial calcium ion homeostasis 0.3904036124361031 0.3382411364326633 0.7351814783660084 1.0 0.9192732422182432 9 Q8IYU8,O95202,Q16891 3 +Nucleus localization 0.361112916095604 0.3382239230089708 0.7351944491254709 1.0 0.9192732422182432 14 O94901,P42345,Q9UH99,Q15154 4 +Positive regulation of chemotaxis 0.333827326885215 0.3378106804961213 0.7355058606949187 1.0 0.9193122776914394 18 Q4KMQ2,Q13641,O94813,O14786,Q13277 5 +Positive regulation of lipid biosynthetic process 0.3898084323017016 0.3357000387651901 0.7370970765866942 1.0 0.9193263265213624 9 Q8WTV0,P04083,P16435 3 +Regulation of peptidase activity 0.2457386423175977 0.3355806047109055 0.7371871518703825 1.0 0.9193263265213624 85 P78318,Q15392,Q9P0J0,O95831,O14737,Q9BXK5,Q92530,Q9NR28,Q6YHK3,P51572,Q9UL46,P05067,P61586,Q9NZJ7,Q96A26,Q92542,Q15418,Q96HY6,P16435,P51812,O76031,Q96K76 22 +Metanephric nephron development 0.4099795739714167 0.3355658464627323 0.7371982825594829 1.0 0.9193263265213624 3 P35222,P11047 2 +Cell differentiation involved in metanephros development 0.4099795739714167 0.3355658464627323 0.7371982825594829 1.0 0.9193263265213624 3 P35222,P11047 2 +Mesenchymal cell proliferation 0.4099795739714119 0.3355658464627158 0.7371982825594954 1.0 0.9193263265213624 3 P02545,P35222 2 +Regulation of mesenchymal cell proliferation 0.4099795739714119 0.3355658464627158 0.7371982825594954 1.0 0.9193263265213624 3 P02545,P35222 2 +Positive regulation of mrna processing 0.3219965453696868 0.3351688988843227 0.7374976815893914 1.0 0.9193738837178452 21 Q9H2U1,Q14011,P98179,P62995,Q13595,Q15427,P38159 7 +Positive regulation of helicase activity 0.453900999569484 0.3349793830302624 0.7376406386042487 1.0 0.9193738837178452 4 Q04837 1 +Positive regulation of golgi to plasma membrane protein transport 0.3669778296382752 0.334790073814771 0.7377834488068777 1.0 0.9193738837178452 2 O95573 1 +Cellular response to camp 0.4375051424772748 0.3316773482581804 0.740132906805181 1.0 0.9207802328106768 6 Q9Y4G8,P05067 2 +Dicarboxylic acid catabolic process 0.4155738330540356 0.3296964270674382 0.7416293537236931 1.0 0.9216339658244488 7 O14734,P00367 2 +Golgi to lysosome transport 0.4448556877815827 0.3295608397119336 0.7417318162619511 1.0 0.9216339658244488 5 Q99523 1 +Sulfur amino acid catabolic process 0.4079369711117755 0.3283032330050461 0.7426823999468297 1.0 0.9216339658244488 3 P25325,Q16762 2 +Positive regulation of synapse assembly 0.4514244788812813 0.3268574108096886 0.7437757345432912 1.0 0.9218617045723294 4 Q13641 1 +Negative regulation of neuron death 0.2632903043885054 0.3263609527071666 0.7441512767828236 1.0 0.9218617045723294 43 P50897,P04062 2 +Mammary gland epithelial cell proliferation 0.4359515361444679 0.3261791290016926 0.7442888312746421 1.0 0.9218617045723294 6 Q9NQC3 1 +Response to purine containing compound 0.3317526567240879 0.3257291976731966 0.7446292514107813 1.0 0.9221092937832698 18 P14625,P21953,P05067,P35613,Q9Y4G8 5 +Cellular response to carbohydrate stimulus 0.2922929781927408 0.3246806099344244 0.7454228113054779 1.0 0.9225896774404896 30 Q15120,P54646,Q15907,P22059,Q8N5M9,Q15043 6 +Microtubule organizing center localization 0.3641733525363517 0.3239943208509046 0.745942333835141 1.0 0.9226014229053192 13 O94901,P33176,O14965,Q9UH99 4 +Phagocytosis recognition 0.4503038652929242 0.3232075107618575 0.7465380931534866 1.0 0.9227428258719348 4 Q8WTV0 1 +Protein localization to synapse 0.3698114070328765 0.3209469051546826 0.7482506274835974 1.0 0.9243261704720191 12 P33176,Q14168,Q9UQB8 3 +Protein insertion into er membrane by stop transfer membrane anchor sequence 0.4415195792696536 0.3182793362655552 0.7502730572372105 1.0 0.9258869369376574 5 Q9NPA0 1 +Leukocyte degranulation 0.3748475307883774 0.3171318649890306 0.7511435470739716 1.0 0.9264302874869368 11 P09601,O00186,P11279,Q99584 4 +Centriole assembly 0.3802972807507707 0.3170250963960563 0.751224559542516 1.0 0.9264302874869368 10 P41208 1 +Negative regulation of defense response to virus 0.4120071114390663 0.3162277867610299 0.7518296183016036 1.0 0.9268759816377912 7 Q96J02,O43657 2 +Positive regulation of neuron differentiation 0.3800457723963929 0.3159374183873012 0.7520500096691931 1.0 0.92692565053517 10 Q8WUJ1,P61586 2 +Regulation of glucose import 0.4115805125452885 0.3146301611207262 0.7530424760918502 1.0 0.9276261926252526 7 Q16625,Q9BZF1 2 +Positive regulation of chromosome segregation 0.3846471873323788 0.3139302692965237 0.7535740001111919 1.0 0.9279325555882232 9 Q00839,Q96GD4,Q14457 3 +Regulation of lymphocyte migration 0.4109902479239049 0.3124243411892907 0.7547180539349017 1.0 0.928818430217709 7 P61586,P05067 2 +Response to activity 0.3433068817850794 0.3121205966112914 0.7549488740629524 1.0 0.928928278942639 16 Q9UDX5 1 +Collateral sprouting 0.4456927207198921 0.3083572800289754 0.7578104847768883 1.0 0.9310526869698448 4 Q9UBN7,P05067 2 +Cellular response to peptide hormone stimulus 0.2617250074850414 0.3021373838315637 0.7625473351512313 1.0 0.934597611741199 66 P20020,Q9BZF1,P43490,P16435,P46108,Q9UQB8,Q8TBX8,Q7L576,Q9BSK2,Q15043 10 +Neuron death 0.2451337622432125 0.3007429031023819 0.763610550433842 1.0 0.9347322603506948 79 P50897,Q15392,Q99720,P09601,P04062 5 +Negative regulation of cell projection organization 0.2874109158479613 0.3004009186895096 0.7638713630140126 1.0 0.9347322603506948 31 Q9NQX7,P61586,P08670,Q9NR77,Q96G23 5 +Regulation of organic acid transport 0.3813202917657233 0.3001571500907933 0.7640572881885328 1.0 0.9347322603506948 9 P55011 1 +Positive regulation of rna splicing 0.3142930612597523 0.3001251989337709 0.7640816587200743 1.0 0.9347322603506948 22 Q14011,P98179,P62995,Q96EP5,Q13595,Q15427,P38159 7 +Neurotrophin trk receptor signaling pathway 0.3856307547103936 0.2991224395482286 0.7648466253846051 1.0 0.9350240540577672 8 P42574,P27695,Q99523,Q7L576 4 +Protein poly adp ribosylation 0.3994747592646795 0.2989004008168205 0.7650160412718556 1.0 0.9350240540577672 3 Q7Z2W4,Q9UGN5 2 +Positive regulation of dna recombination 0.2888173239301459 0.2974983533357968 0.7660860649669359 1.0 0.9356497028100104 30 P35637,Q9UNS1,O96028,Q8TAF3,Q96FZ2,Q7Z4V5 6 +Mitotic chromosome condensation 0.3700230720064806 0.2957603580521321 0.7674130989426489 1.0 0.9359232553003856 11 Q9ULX6,Q9UIG0,P53350,P42695 4 +Mechanoreceptor differentiation 0.3846665632079022 0.2953039686952692 0.7677616850597606 1.0 0.9359232553003856 8 Q9Y6M7,P54802 2 +Epidermis development 0.2597203211279206 0.2949480593567256 0.7680335580451807 1.0 0.9359232553003856 49 O75844,P51648,P16615,P04083,Q13510,O60568 6 +Mammary gland development 0.319038632899739 0.2949358203294058 0.7680429077341739 1.0 0.9359232553003856 19 Q99623,Q13505,P00403,Q9NQC3 4 +Positive regulation of pattern recognition receptor signaling pathway 0.3799975839041237 0.2947393137219247 0.7681930285047054 1.0 0.9359232553003856 9 Q9NQC3 1 +Dna replication independent chromatin organization 0.4059065970951386 0.2936579085753055 0.7690193209225233 1.0 0.9363973661782322 7 O14929 1 +Receptor catabolic process 0.3748244189114385 0.2936337188864903 0.7690378070609263 1.0 0.9363973661782322 10 P46934 1 +Positive regulation of metaphase anaphase transition of cell cycle 0.3747383350017698 0.2932704948655157 0.7693154043198531 1.0 0.9363973661782322 10 Q9UJX4,Q14674,Q96MF7,Q13042 4 +Peptidyl arginine modification 0.3837215118667936 0.2915780007444451 0.7706092977297709 1.0 0.9373052248645156 8 Q6P2P2,O14744 2 +Nucleoside metabolic process 0.3184340135692419 0.2913865320989597 0.7707557137105954 1.0 0.9373052248645156 19 O60725,Q13126 2 +Establishment of mitotic spindle localization 0.3455789899447645 0.2908336665817906 0.7711785355364844 1.0 0.9373495496146328 15 P42858,O14777,P53350 3 +Production of molecular mediator involved in inflammatory response 0.3687967201395523 0.2904036923749258 0.7715074192568405 1.0 0.9373495496146328 11 Q8IV08 1 +Synaptic vesicle exocytosis 0.3454585370782776 0.2902281523669419 0.7716417001685139 1.0 0.9373495496146328 15 Q4J6C6,Q06787,Q13277,P16615 4 +Ventricular trabecula myocardium morphogenesis 0.3550175029171527 0.2895882992662397 0.7721312194551528 1.0 0.9375879093384 2 Q9P2D1 1 +Heart trabecula morphogenesis 0.3550175029171527 0.2895882992662397 0.7721312194551528 1.0 0.9375879093384 2 Q9P2D1 1 +Negative regulation of leukocyte apoptotic process 0.4392877991827266 0.2881915440814322 0.7732001211852033 1.0 0.938191419233969 4 P14174,Q96GD4,P78540 3 +Negative regulation of lymphocyte apoptotic process 0.4392877991827266 0.2881915440814322 0.7732001211852033 1.0 0.938191419233969 4 P14174,Q96GD4,P78540 3 +Tumor necrosis factor superfamily cytokine production 0.3144049580791111 0.2878780843665507 0.7734400632427101 1.0 0.9383090580511488 21 P30536 1 +Mitochondrial dna replication 0.3777536208294719 0.285625011024946 0.7751653451160441 1.0 0.9398808194108428 9 Q9BQP7,Q04837,Q96QE5,P23921,Q96RR1 5 +Glutathione metabolic process 0.3042383378256619 0.2841786530612738 0.776273473761754 1.0 0.9404024440356704 25 O75874 1 +Cellular response to vascular endothelial growth factor stimulus 0.3814215891610441 0.2825801377785762 0.7774987077770945 1.0 0.9413185462054048 8 O14786,P04083 2 +Cellular glucose homeostasis 0.2771513093520902 0.2815398646896875 0.7782963564387131 1.0 0.941589360426039 36 P52789,Q15120,P54646,Q15907,P22059,Q8N5M9,Q15043 7 +Positive regulation of lymphocyte differentiation 0.3716448421171954 0.2803168234098205 0.7792344447666131 1.0 0.942045747916486 10 P04083 1 +Hematopoietic progenitor cell differentiation 0.2904438948285771 0.2801467145129234 0.7793649459801735 1.0 0.942045747916486 29 Q9H2U1,Q96J02,Q9NUQ2,P78527,Q96PZ0,O94874,Q9NPH0,A0AV96,Q9Y5A9 9 +Positive regulation of nucleobase containing compound transport 0.4365720852799779 0.2798076473531085 0.7796250842329986 1.0 0.942045747916486 4 Q07666 1 +Positive regulation of rna export from nucleus 0.4365720852799779 0.2798076473531085 0.7796250842329986 1.0 0.942045747916486 4 Q07666 1 +Cellular hyperosmotic response 0.4294769874580595 0.2788172753339166 0.7803850561897956 1.0 0.9421567973203216 5 O95202,Q92974 2 +Negative regulation of rna splicing 0.3230068813116324 0.276078566530009 0.7824877225913687 1.0 0.9435289297399048 18 P61978,Q9UKA9,P26368,P22626,P98175,P38159 6 +Positive regulation of adaptive immune response 0.3228847558153889 0.2754005414851515 0.7830085281194381 1.0 0.9439834579312424 18 P01889,P04439,O96028,Q9NUQ9,Q96FZ2 5 +Neurotransmitter metabolic process 0.4210267180230607 0.2751101684916709 0.783231599579727 1.0 0.9440789413009126 6 P21964 1 +Regulation of dna catabolic process 0.4279557916599209 0.2739781320379318 0.7841014269908555 1.0 0.9449538225737362 5 Q13315 1 +Response to mineralocorticoid 0.4001994281128677 0.273096952952513 0.7847786889263557 1.0 0.9451438929695825 7 P20020 1 +Rna splicing 0.2379059654460163 0.2706633840404824 0.7866499412037351 1.0 0.9464607470075008 237 P55769,Q14011,P78332,P61978,Q9BWJ5,P14866,P52756,P17844,P67809,P11940,Q13107,Q96MU7,Q9ULX6,Q96FV9,P98175,Q9BWF3,O14776,P98179,P51991,Q13595,P07910,Q15427,Q07666,O60506,Q16637,P52597,O43390,P55795,P62995,P31483,Q9UKA9,P23246,Q96EP5,P31943,Q06787,O14744,P26368,Q92945,P51114,Q9UKM9,P22626,P62316,P31942,Q14562,Q6P2Q9,Q92804,P38159,Q5BKZ1,Q00839,P51116,Q07021,O95391,P35637,Q96PK6,Q08211,Q9UHX1,Q01081,Q9UHI6,O75400 59 +Regulation of response to stress 0.2358213457502021 0.2700602112287293 0.78711393195751 1.0 0.9466718514488968 269 P46379,P61978,P57088,Q9NP80,P67809,P78318,P11279,O00560,Q92974,Q9UNS1,Q13315,Q9UBN7,O95202,Q8NCG7,Q96FV9,P04083,Q8TAF3,Q7Z4V5,P04062,P07900,O75844,P08183,Q9NUD5,Q4KMQ2,Q96J02,Q969S3,P78527,Q9Y5Z4,P46108,O95881,Q9NZ08,Q6YHK3,O43657,P55011,P23246,P43243,Q06787,P00374,P05067,O15360,Q96QE3,Q13535,P51114,O96028,Q16625,P42345,Q16543,P51116,O76024,O14936,P35637,Q96PK6,P01889,P04439,Q08211,Q07820,Q96HY6,O60313,Q96G23,Q96K76 60 +Regulation of neuron differentiation 0.3070822386997416 0.268954761556628 0.787964495339081 1.0 0.9475149241093273 23 Q8WUJ1,P61586,P05067,Q92974,Q96JB5 5 +Lipid import into cell 0.4190476524981263 0.2685862550604584 0.7882480906298106 1.0 0.9475149241093273 6 O14975 1 +Positive regulation of leukocyte cell cell adhesion 0.3091624631162901 0.2681164208479804 0.7886097064259572 1.0 0.9476024342734172 22 P04439,P30825,P61586,P04083 4 +Cellular response to interferon gamma 0.3087636838970973 0.2656645590281442 0.790497560569625 1.0 0.948508369150996 22 P08670,O60506,Q16543 3 +Fat cell differentiation 0.2918999857336078 0.2643758835770874 0.7914902927418677 1.0 0.9489712799019496 28 Q6IAN0,Q00839,Q9BZF1,Q8N4Q0,Q9BRK5,Q99523,Q9NZ08 7 +Negative regulation of interleukin 12 production 0.3889699445579426 0.2640083200247433 0.7917735076901877 1.0 0.9489712799019496 3 Q07021,Q8WXW3 2 +Negative regulation of smooth muscle cell apoptotic process 0.3889699445579325 0.264008320024711 0.7917735076902126 1.0 0.9489712799019496 3 Q8NDZ4,P26358 2 +Positive regulation of lipase activity 0.397053330235112 0.2619994836498194 0.7933218402765119 1.0 0.949786155061936 7 P61586 1 +Fatty acid derivative biosynthetic process 0.345215501246032 0.2605296852486328 0.7944552201662363 1.0 0.9500645928925536 14 Q53GQ0,P50897 2 +Neutrophil activation involved in immune response 0.430098525246207 0.2602343595095869 0.7946830019751918 1.0 0.9500645928925536 4 O00186,P51809 2 +Neutrophil degranulation 0.430098525246207 0.2602343595095869 0.7946830019751918 1.0 0.9500645928925536 4 O00186,P51809 2 +Positive regulation of b cell mediated immunity 0.3667488363111988 0.2602180227852994 0.794695602839524 1.0 0.9500645928925536 10 Q96FZ2,O96028 2 +Axo dendritic protein transport 0.4300225658656652 0.2600081923729573 0.7948574542792015 1.0 0.9500645928925536 4 Q14168 1 +Protein localization to presynapse 0.4300225658656652 0.2600081923729573 0.7948574542792015 1.0 0.9500645928925536 4 Q14168 1 +Positive regulation of isotype switching 0.3710674707001527 0.2590580402363353 0.7955904589020582 1.0 0.9505944266779508 9 Q96FZ2,O96028 2 +Negative regulation of cellular response to insulin stimulus 0.3957036730688373 0.2572914929417227 0.7969537591068965 1.0 0.9518766958972432 7 Q8TBX8,Q9HCD5 2 +Positive regulation of t cell mediated immunity 0.374363636609925 0.2556016958719286 0.798258408777373 1.0 0.9525889922914272 8 P01889,P04439 2 +Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery 0.421313868613143 0.2532473798070956 0.8000770557001802 1.0 0.9533923322548556 5 P57740,Q8WUM0,O75694,Q5JVF3 4 +Intrinsic apoptotic signaling pathway in response to dna damage 0.2995725125035078 0.253229964159459 0.800090512880635 1.0 0.9533923322548556 25 P46379,P61978,Q13315,Q96QE3,Q07820,P09601,Q96K76 7 +Positive regulation of potassium ion transport 0.3695623954306447 0.2532028213797608 0.8001114863955332 1.0 0.9533923322548556 9 Q4KMQ2 1 +Inner ear receptor cell development 0.394251043026904 0.2522601444854207 0.8008399922044984 1.0 0.9540871512065938 7 Q9Y6M7,P54802 2 +Positive regulation of transcription by rna polymerase iii 0.3691745326081383 0.2517015188660255 0.8012717829050817 1.0 0.9541939308304244 9 Q9NR30,P42345,Q9NY93,O75533,Q9UIG0 5 +Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.4271168485677807 0.251418486023393 0.8014905768441607 1.0 0.9541939308304244 4 P11940 1 +Substantia nigra development 0.3251973015859826 0.2513917196853896 0.8015112689328405 1.0 0.9541939308304244 17 P24539,P61586,P14854 3 +Actin myosin filament sliding 0.3436406067677958 0.2492577873665015 0.8031613817591581 1.0 0.9552918229297798 2 P09493 1 +Proteolysis 0.2284343211994693 0.2482310154465984 0.8039556703176047 1.0 0.9555577523319152 414 P46379,Q9UIQ6,Q9UBU6,O00560,Q9UBV2,P49721,Q92896,Q13042,Q15392,Q8TAF3,Q96FZ2,Q6P179,Q9H4L4,Q9P0J0,P04062,O75844,Q8TCT9,O14773,Q99797,Q10713,O14737,O95831,Q9HB40,P14625,P67812,Q92820,Q9BXK5,Q9UHG3,Q9Y6J9,Q9NZ08,Q2T9J0,Q96KC8,O43292,P42892,Q5VYK3,P28072,Q06787,Q9H3G5,P05067,P61586,P42785,Q9NZJ7,Q96PU5,Q5JRX3,Q9BYT8,P38159,Q96A26,P10619,Q15418,P46934,P16435,Q6ZXV5,O75503,Q9BUN8,P48729,Q4J6C6,Q96JB5,Q96HY6,Q96A33,O76031,Q96K76 61 +Regulation of t cell mediated immunity 0.3676435256149715 0.2458061255398737 0.8058323150289077 1.0 0.9561295054214652 9 P01889,P04439 2 +Regulation of cell projection organization 0.2419347858670076 0.2448478618420394 0.8065742331909003 1.0 0.9567498405999072 123 Q9UQB8,Q32P28,Q9P2S5,P46108,Q9Y277,Q7L576,Q14108,Q06787,Q9Y2A7,P61586,Q96PU5,P51114,P08670,Q16625,Q9NQX7,P42345,P51116,P46934,Q9NQC3,Q9HCE1,Q9NR77,Q96G23 22 +Endocrine system development 0.3467925993486068 0.243283825108912 0.8077855337347579 1.0 0.9572242580063928 13 P30536 1 +Receptor signaling pathway via stat 0.3298765793638603 0.2430339612795111 0.8079790887151126 1.0 0.9572242580063928 16 O95630,Q9NX40,Q9H490,P22059,P30153 5 +Positive regulation of interleukin 1 production 0.3708672929230553 0.2426023909120385 0.8083134288625895 1.0 0.9572242580063928 8 Q99584,P05067 2 +Positive regulation of actin filament polymerization 0.3413478662299912 0.2425511253621897 0.8083531469183416 1.0 0.9572242580063928 14 Q9UQB8,Q9Y2A7,P61586 3 +Regulation of nik nf kappab signaling 0.3234127574199948 0.2421458055669801 0.808667186371457 1.0 0.9572242580063928 17 P05067,P61586,O43657 3 +Calcium ion export 0.4168538845684107 0.2396990252019504 0.8105635906930215 1.0 0.958536363692126 5 P20020 1 +Regulation of dendrite development 0.3062479731680196 0.2390799443310186 0.8110435929862514 1.0 0.9587584322060496 21 P46934,P61586,P46108,Q9UQB8,Q96PU5 5 +Positive regulation of production of molecular mediator of immune response 0.2998899069745315 0.2386565616031161 0.8113719022965544 1.0 0.9589737793353728 24 Q99623,Q9H2U1,O96028,P04439,Q96FZ2 5 +Endothelial cell proliferation 0.3091699889196093 0.2384138935689503 0.8115600925640998 1.0 0.9590234697290876 19 Q8WTV0,P09601 2 +Ventricular septum development 0.409211707419268 0.237072016802977 0.8126009209550986 1.0 0.9595267701880112 6 P43243,O96028 2 +B cell activation 0.2599420176463581 0.2367614007493474 0.8128418979507861 1.0 0.9595267701880112 41 Q99623,P78318,P52701,Q5HYI8,P05141,Q13315,P78527,Q9UQ84,Q96QE3,O96028,Q96FV9,Q96FZ2 12 +Regulation of dna duplex unwinding 0.4217746643315877 0.2359459233915043 0.8134746323548956 1.0 0.9599153763011774 4 P49736,Q04837,P11388 3 +Regulation of cardiac conduction 0.4155479715566524 0.2357898092285093 0.8135957762887798 1.0 0.9599153763011774 5 P16615 1 +Maintenance of sister chromatid cohesion 0.4147193847970558 0.2333231912797009 0.8155104514751086 1.0 0.9610954710092784 5 Q9Y6X3 1 +Regulation of cell aging 0.349936793051272 0.2327239165075761 0.8159757963773415 1.0 0.9611942644142982 12 O75844 1 +Myeloid leukocyte mediated immunity 0.3277439232219223 0.2325163839111402 0.8161369633616489 1.0 0.9611942644142982 16 Q9H2U1,P09601,Q99584,Q8N5M9 4 +Peptidyl lysine acetylation 0.2564879709436416 0.2323462385184918 0.8162691017554706 1.0 0.9611942644142982 58 O75844,P16435,P54646,Q86UY6,O14929,Q9Y6J9 6 +Cytoplasmic pattern recognition receptor signaling pathway in response to virus 0.3390323619702298 0.2319726624639726 0.8165592468857477 1.0 0.9611942644142982 14 Q9NUD5,O43657 2 +Interleukin 6 mediated signaling pathway 0.3787569302597144 0.2318949179565069 0.8166196318362866 1.0 0.9611942644142982 3 Q6PD62,Q13546 2 +Regulation of response to endoplasmic reticulum stress 0.3049251785077017 0.2313775868846066 0.8170214758552619 1.0 0.9614947856101556 21 P46379,O76024,O95881,Q96HY6,O60313 5 +Organelle transport along microtubule 0.2709957586102923 0.230130680907609 0.817990224706012 1.0 0.9622122911361218 36 Q8TD16,P42858,P27695,P33176,P11279,O94901,Q9UBN7,Q5SNT2,O60313,Q9Y2T2,Q9UBK9 11 +Vesicle transport along microtubule 0.3330879223445255 0.230026636543375 0.8180710716623627 1.0 0.9622122911361218 15 P27695,P42858,P33176,Q9Y2T2 4 +Regulation of hematopoietic stem cell differentiation 0.3670354880930258 0.2286428225167214 0.81914653850232 1.0 0.9627869578456428 8 P78527,Q96J02,Q96PZ0 3 +Odontogenesis of dentin containing tooth 0.3665661519514154 0.2269539685731136 0.8204595359339231 1.0 0.9639381066658604 8 Q13547,P35613,Q07812,Q6P4Q7 4 +Glutamine family amino acid biosynthetic process 0.3865663874790727 0.2262750006344429 0.8209875407868474 1.0 0.9639381066658604 7 O75746,P54886,P00367 3 +Regulation of telomere capping 0.3534774067142198 0.226242703932598 0.8210126585986528 1.0 0.9639381066658604 11 Q14103 1 +Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 0.4123035962234728 0.2261929523294289 0.8210513518066995 1.0 0.9639381066658604 5 P30154 1 +Leukocyte apoptotic process 0.3055142528210278 0.2256531014125788 0.8214712368848274 1.0 0.9639381066658604 20 P24390 1 +Myeloid leukocyte activation 0.2977866579864254 0.2254933889045323 0.821595467840154 1.0 0.9639381066658604 24 P09601,P05067,P04083 3 +Protein localization to extracellular region 0.2541397073438931 0.2253304889472552 0.8217221827335015 1.0 0.9639381066658604 67 Q9UBV2,P53985,Q9HCU5,Q15907,P04083,O75592,Q32P28,P00367,P22059,Q5T9L3,Q96KC8,P55011,Q16850,O95563,P27824,Q96PC5,P04049,Q9H4A6,Q16836,Q8N5M9 20 +Hyperosmotic response 0.3862732670084061 0.2253052551510437 0.8217418117477633 1.0 0.9639381066658604 7 P55011,O95202,Q92974 3 +Pattern specification process 0.270242985701418 0.2239742373034449 0.8227773496644346 1.0 0.9646658736623192 36 Q8N2A8,P62995,Q8IZP0,O14786,O14965,Q9Y366,Q9UK61,Q13315,Q9Y2W6,O75569,Q5T9L3 11 +Centromeric sister chromatid cohesion 0.4110842844792382 0.2226290555879074 0.8238242208281172 1.0 0.9650008099025535 5 O60566,O43683,P30153 3 +G2 mi transition of meiotic cell cycle 0.3752204557832135 0.2212089686507063 0.8249297262619961 1.0 0.9657009753164878 3 O14777 1 +Prostanoid biosynthetic process 0.3568402389826774 0.2211229560594589 0.8249966962883206 1.0 0.9657009753164878 10 Q9NP80,P04083,Q9H7Z7 3 +Positive regulation of sodium ion transport 0.3609314168405643 0.2205493976024664 0.8254433055991464 1.0 0.9659095605939908 9 Q99959,O43865 2 +Meiotic chromosome separation 0.4099270072992749 0.2192683096715916 0.8264410464481313 1.0 0.9663450756152004 5 Q14674,P33981,Q15003,P11388 4 +Post embryonic development 0.3188315396654565 0.2188478127327593 0.8267686003484997 1.0 0.966551853819144 17 P42345,O95470,Q96A33 3 +Regulation of mitotic cell cycle spindle assembly checkpoint 0.4029348715759764 0.2177796661951816 0.8276007883471734 1.0 0.9671801198814162 6 O14777,P14635 2 +Regulation of defense response 0.2401017003707854 0.217574072343708 0.8277609878071699 1.0 0.9671950858245458 97 P11279,Q13315,Q8NCG7,P04083,Q9NUD5,P07900,O75844,P04062,Q96J02,P46108,Q9NZ08,O43657,P23246,P43243,O15360,P05067,Q16543,Q96PK6,P01889,P04439,Q08211 21 +Positive regulation of programmed necrotic cell death 0.3737963233148685 0.216970349938135 0.8282314518462814 1.0 0.967572509705412 3 P04637,Q13546 2 +Response to peptide hormone 0.2387524921626304 0.2159084538487648 0.829059107299065 1.0 0.9682948814911564 91 P20020,P35613,Q9UQB8,P04083,P43490,P11166,P08574,P49770,P78527,P46108,Q7L576,Q9BSK2,Q15043,Q9BZF1,Q99523,O43865,P42345,P16435,Q8TBX8,Q16836 20 +Regulation of cellular response to heat 0.3554252685136594 0.2157196127839328 0.8292063123518834 1.0 0.9682948814911564 10 Q13535,P42345 2 +Positive regulation of signal transduction by p53 class mediator 0.3455039453225905 0.2143026105005638 0.8303110824425912 1.0 0.968727451381864 12 Q13315,Q13535,Q96JB5 3 +Homocysteine metabolic process 0.408175182481756 0.2142216963575231 0.8303741775444802 1.0 0.968727451381864 5 P25325,Q16762,P42898,P22033 4 +Trna wobble base modification 0.4017418711750428 0.2141871913665164 0.8304010841241976 1.0 0.968727451381864 6 Q9Y2Z2,O75648 2 +Trna wobble uridine modification 0.4017418711750428 0.2141871913665164 0.8304010841241976 1.0 0.968727451381864 6 Q9Y2Z2,O75648 2 +Positive regulation of lipid catabolic process 0.3725572274553644 0.2133129042324796 0.8310829090554466 1.0 0.969178256481578 3 Q8NCG7 1 +Positive regulation of i kappab kinase nf kappab signaling 0.2544453228037713 0.2126561005573563 0.8315952101793016 1.0 0.9694311190613922 42 Q86UE4,P61586,Q8TB61,P09601,O43657 5 +Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway 0.3810388213090643 0.2082594511169398 0.8350263907783033 1.0 0.972166962497177 7 O60313,O95881 2 +Response to nitrogen compound 0.2346961363548435 0.2076801990416027 0.8354786794616864 1.0 0.972166962497177 252 P46379,P30536,P20020,Q9UBV2,Q9UBU6,Q92974,Q9UNS1,P49721,P35613,Q14103,Q9UQB8,P04083,Q99707,Q9NUD5,O95831,Q8TCT9,P43490,Q99729,P08574,P14625,P49770,P46108,Q7L576,O75477,Q9BSK2,Q15043,Q9H2U1,Q9BZF1,Q5VYK3,Q06787,P00374,P05067,P61586,O14744,P08670,Q99523,Q6NTF9,P34896,P23378,Q13438,O43865,P42345,Q92542,O76024,P16435,Q9BUN8,O15118,Q8TCJ2,Q8TBX8,Q08211,Q96A33 51 +Ribonucleotide catabolic process 0.3527911466404485 0.2057839727103397 0.8369596611873329 1.0 0.972919273110944 10 A8MXV4,P35610,P49902 3 +Regulation of calcium ion transmembrane transport 0.2943395033920473 0.2042871452619266 0.8381291147527103 1.0 0.9735888212085828 24 P21796,Q96GC9 2 +Regulation of telomerase activity 0.2978008636962804 0.2004420901849191 0.8411348441441922 1.0 0.9753537457632424 22 Q13315,Q14103,P27544,P22626,P07900 5 +Rna localization 0.239549626898556 0.1995422944987007 0.8418385622785904 1.0 0.9758248799986065 119 Q8TD16,P67809,Q13315,Q96MU7,Q9ULX6,Q96FV9,Q5SRE5,P51991,Q7Z3B4,Q99567,Q99729,Q07666,Q9H2U1,Q06787,Q13535,Q92945,P22626,P41208,Q9BTX1,Q8N1F7,Q9HAV4,Q00839,Q12769,Q8NFH4,Q08211 25 +Cellular response to topologically incorrect protein 0.2631637006156314 0.1982625770799596 0.8428396296270892 1.0 0.9761231291233604 38 P46379,P57088,O76024,Q9BUN8,Q9UBN7,Q96JB5,Q6NTF9,Q9Y4P3,Q96HY6,Q13438,Q0VDF9 11 +Rrna 5 end processing 0.4023614867492396 0.1978295424877607 0.8431784313788893 1.0 0.9763431915843076 5 P78316,Q86U38 2 +Negative regulation of endocytosis 0.3260327234582984 0.197564243837615 0.8433860126200798 1.0 0.9764112587884552 15 O00560,P05067 2 +Positive regulation of neurogenesis 0.2497717483931879 0.1967290005223719 0.8440396144230098 1.0 0.976907527502502 43 P30536,P42345,Q16706,O14786,O14744,P55209,Q9UQB8,Q7L576 8 +Positive regulation of protein exit from endoplasmic reticulum 0.4074433604294742 0.1965561407486841 0.8441748955729456 1.0 0.976907527502502 4 Q92544 1 +Embryo implantation 0.3410412433055753 0.1962555330839427 0.8444101639735129 1.0 0.976907527502502 12 Q96GC9 1 +Positive regulation of cell junction assembly 0.3309142950103139 0.196024835350782 0.8445907272897073 1.0 0.97694418340826 14 O14786,Q13641,O75955,Q9Y2S7 4 +Ribonucleoside triphosphate biosynthetic process 0.2784990982618574 0.1941731608091148 0.8460402974738268 1.0 0.9779313778445043 29 P00403,O75964 2 +Protein n linked glycosylation 0.3137562183489275 0.1938001721003248 0.8463323522505639 1.0 0.978096670565023 17 Q86YN1,Q9BT22,P04844,P46977,Q9H0U3,Q2TAA5 6 +Carbohydrate homeostasis 0.2500405789085329 0.1928959131105503 0.8470404857923457 1.0 0.9781531091353048 50 P52789,Q15120,O76024,P54646,P42785,P53985,Q15907,P22059,Q8N5M9,Q15043 10 +Regulation of synapse structural plasticity 0.3261376896149345 0.1927164621213033 0.8471810302218916 1.0 0.9781531091353048 2 Q14012 1 +Regulation of epithelial to mesenchymal transition 0.3523567751117887 0.1897315243985868 0.8495195165812714 1.0 0.9784650512607668 9 O00560 1 +Circadian regulation of gene expression 0.2987534061985235 0.1884321936774979 0.8505378647852593 1.0 0.9784650512607668 20 Q00839,P43490,Q03164,O14744,O75592,Q9Y5V3 6 +Regulation of defense response to virus by host 0.3746509890697758 0.1881688544146817 0.8507442869209567 1.0 0.9784650512607668 7 Q08211 1 +Organelle fission 0.2365384925712797 0.1879490027621692 0.8509166285250074 1.0 0.9784650512607668 168 Q99623,Q14674,P46379,Q8TB36,O14965,O14734,Q13042,Q13315,O14777,Q9ULX6,Q14457,Q86XL3,Q9UJX4,O43683,Q12768,Q9BZD4,Q9P2S5,Q9UDX5,Q96DY7,Q9Y2W6,Q9Y2S7,P42695,O15360,P61586,O14744,Q9NUQ9,Q92791,Q9BTX1,Q96DB5,Q00839,Q9Y6X3,O94901,Q9NQG6,P53350,Q96MF7,O60313 36 +Protein kinase b signaling 0.2866768379254712 0.187696954262081 0.8511142179840241 1.0 0.9784650512607668 26 P42345,Q13641,Q969H8,Q9BZF1,Q86UE4,Q9NQC3,Q07021,P07900 8 +Positive regulation of muscle tissue development 0.3635833090166504 0.1876839273928917 0.851124430447479 1.0 0.9784650512607668 3 P35222,O75955 2 +Positive regulation of skeletal muscle tissue development 0.3635833090166504 0.1876839273928917 0.851124430447479 1.0 0.9784650512607668 3 P35222,O75955 2 +Negative regulation of notch signaling pathway 0.3635833090166434 0.1876839273928722 0.8511244304474943 1.0 0.9784650512607668 3 O00308,Q9Y5A9 2 +Mitotic dna replication 0.3431949423410879 0.1862401304118607 0.85225645492086 1.0 0.9791041375793108 11 O75844 1 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.3176810112931606 0.1847056677318311 0.8534599004642134 1.0 0.9799481831751824 16 Q96FZ2,Q9UQ84,O96028,Q96FV9 4 +Somatic diversification of immunoglobulins involved in immune response 0.3176810112931606 0.1847056677318311 0.8534599004642134 1.0 0.9799481831751824 16 Q96FZ2,Q9UQ84,O96028,Q96FV9 4 +Neuromuscular junction development 0.332643196319565 0.1830775525730293 0.8547371685383411 1.0 0.9808998425933184 13 P46934 1 +Neural nucleus development 0.2987461502705949 0.1822268607786221 0.855404694042583 1.0 0.9811566374793612 19 Q16352,P24539,P61586,P14854,O95487 5 +Regulation of t cell activation 0.2664901689219512 0.182030209054777 0.8555590185396076 1.0 0.9811566374793612 35 O15360,O96005,P61586,P30825,P04439,P04083 6 +Regulation of hematopoietic progenitor cell differentiation 0.3369645832170426 0.1802197571083177 0.856980048444421 1.0 0.9817568222577324 12 P78527,Q9H2U1,Q96J02,Q96PZ0 4 +Regulation of mitotic cell cycle phase transition 0.2379393381733971 0.1774387536281886 0.8591637692441743 1.0 0.9828270185833266 102 Q99623,Q14674,Q96GD4,P27695,O14965,O43670,Q13042,Q13315,O14777,P04083,Q9UJX4,Q92547,O43683,Q9Y619,Q96DY7,P78527,Q5TBB1,Q7L7X3,Q6NUQ1,Q9UL46,P05067,P31350,Q96QE3,Q96JB5,P53350,Q96MF7,Q96K76 27 +Cytoskeleton dependent intracellular transport 0.2409673367052408 0.1757000941301909 0.8605295613497648 1.0 0.9828270185833266 75 Q8TD16,P27695,O94832,P11279,O43805,Q9UBN7,O43707,Q5SNT2,Q9UBK9,Q15154,P33176,Q9UH99,P07437,Q14168,P42858,A0AVF1,P23246,P05067,Q9Y2T2,Q00839,Q9Y366,O94901,O60313 23 +Regulation of secretion 0.2364566845291132 0.175251950233306 0.8608816655310296 1.0 0.9828270185833266 94 P27695,O00560,P11279,Q9Y5X3,P16615,P53985,P04083,O75592,P49755,O14964,Q32P28,P00367,P40939,P09601,P22059,Q5T9L3,Q96KC8,P55011,P05771,Q06787,Q16850,Q8IWT6,O95563,O00186,Q9H4A6,O14936,Q4J6C6,Q16836,Q8N5M9 29 +Regulation of response to dna damage stimulus 0.2349231327303453 0.1750365138345228 0.8610509425650212 1.0 0.9828270185833266 88 O75844,P61978,P51116,Q06787,P35637,Q9UNS1,Q13315,Q96QE3,Q13535,P51114,Q08211,O96028,Q96FV9,Q8TAF3,Q7Z4V5,Q96K76 16 +Cellular senescence 0.2948018521161741 0.1745336174747436 0.861446113268497 1.0 0.9828270185833266 21 Q13315,P67809,O75844,O60313 4 +Heart morphogenesis 0.2690696810795102 0.1744121528194683 0.861541564129473 1.0 0.9828270185833266 32 O75844,P42345,Q9NQC3,O14786,Q99959,Q9Y366,O96028,P10253 8 +Cellular response to uv 0.272115950176832 0.1740171001415129 0.8618520232981657 1.0 0.9828270185833266 30 P46934,Q06787,Q13535,P27544,Q96K76 5 +Natural killer cell activation involved in immune response 0.3585556814988755 0.1739980776989991 0.8618669729617057 1.0 0.9828270185833266 3 P11279 1 +Natural killer cell degranulation 0.3585556814988755 0.1739980776989991 0.8618669729617057 1.0 0.9828270185833266 3 P11279 1 +Cellular response to hormone stimulus 0.2367549386431306 0.1739479937211308 0.8619063340016266 1.0 0.9828270185833266 135 P20020,Q9UQB8,P04083,O95831,P43490,P46108,Q7L576,Q9BSK2,Q15043,Q9BZF1,P54646,P61586,P42785,Q9H7B4,O15173,P46934,P16435,O15118,Q8TBX8,Q96HY6 20 +Regulation of striated muscle contraction 0.3153028464402265 0.1738631033175391 0.8619730502236562 1.0 0.9828270185833266 16 Q9HD47,Q99959,P16615 3 +Positive regulation of b cell activation 0.3397914750549581 0.1735780686418886 0.8621970690433671 1.0 0.9828270185833266 11 Q96FZ2,O96028 2 +Negative regulation of wound healing 0.3432490160698274 0.1711725462200325 0.8640880938224833 1.0 0.9828270185833266 10 O14936,P46108,P55011 3 +Regulation of muscle contraction 0.2887340655572084 0.1708230378533748 0.8643629137351982 1.0 0.9828270185833266 24 P20020,Q9HD47,Q99959,P61586,P16615 5 +Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway 0.3430294148366812 0.1704020811719875 0.8646939355408392 1.0 0.9828270185833266 10 O43657 1 +Regulation of b cell activation 0.3028268231715597 0.1704016347288523 0.8646942866166853 1.0 0.9828270185833266 18 Q13315,Q96FZ2,O96028,Q96FV9 4 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.3499586489609323 0.1702624242952359 0.8648037608101835 1.0 0.9828270185833266 8 P46379,O43681,Q9UGP8 3 +Cellular response to hydrogen peroxide 0.2885429634379174 0.1697052141893703 0.865241973227564 1.0 0.9828270185833266 24 Q99720,P04083,Q14457 3 +Protein targeting to peroxisome 0.3967807911055517 0.1693348318219684 0.8655332797399893 1.0 0.9828270185833266 4 P40855 1 +Negative regulation of mrna splicing via spliceosome 0.3142637087144155 0.1691822444248594 0.8656532953656011 1.0 0.9828270185833266 16 P98175,P38159,P22626 3 +Amine transport 0.3495966887530002 0.169095354946039 0.8657216385357118 1.0 0.9828270185833266 8 P55011 1 +Negative regulation of lipid biosynthetic process 0.3462585078675633 0.1688436014832886 0.8659196616155476 1.0 0.9828270185833266 9 Q8NF37,O75477 2 +Regulation of protein localization to plasma membrane 0.2808746027766401 0.1684368214622787 0.8662396425552534 1.0 0.9828270185833266 27 Q9HD47,P33176,O00264 3 +Positive regulation of dna damage response signal transduction by p53 class mediator 0.3911021712122186 0.1676774073282854 0.8668370708613637 1.0 0.9828270185833266 5 Q13315,Q13535 2 +Hematopoietic stem cell differentiation 0.33340762943023 0.1665885471710567 0.8676938058026527 1.0 0.9828270185833266 12 Q96J02,Q96PZ0,P78527,O94874,Q9Y5A9 5 +Positive regulation of glial cell differentiation 0.3673963452548374 0.1663284411967644 0.8678984849403251 1.0 0.9828270185833266 7 P42345 1 +Positive regulation of transmembrane transport 0.265665924434574 0.1656927869634949 0.8683987227607111 1.0 0.9828270185833266 34 P08183,P42858,Q4KMQ2,Q16625,Q96GC9 5 +Tissue migration 0.250322773113576 0.1651638222241582 0.8688150398269268 1.0 0.9828270185833266 59 P42345,Q8WTV0,P61586,P57105,P42785,P04083,P09601 7 +Hair follicle maturation 0.390072992700735 0.1650284789628008 0.8689215664041245 1.0 0.9828270185833266 5 Q5C9Z4,P35222,P18074,Q08J23 4 +Embryonic hindlimb morphogenesis 0.3551210971695481 0.1649318578221748 0.8689976168577356 1.0 0.9828270185833266 3 P35222,Q9P2D1 2 +Hindlimb morphogenesis 0.3551210971695481 0.1649318578221748 0.8689976168577356 1.0 0.9828270185833266 3 P35222,Q9P2D1 2 +Regulation of striated muscle cell differentiation 0.3326144407885245 0.1635953935074222 0.8700496712969732 1.0 0.9835083450561134 12 P42345,Q9BYT8 2 +Establishment of protein localization to endoplasmic reticulum 0.2908479333795231 0.1614175133221515 0.8717645739087772 1.0 0.9839947912400488 22 P46379,Q15629,Q9Y5M8,Q9UGP8 4 +Positive regulation of plasma membrane bounded cell projection assembly 0.2768304118479954 0.1613122951217201 0.8718474399733023 1.0 0.9839947912400488 28 P42858,P42345,Q9P2S5,Q06787,Q9Y2A7,Q7L576,Q16625 7 +Rna secondary structure unwinding 0.3921926636454441 0.1581872952556141 0.874309214624168 1.0 0.9855782802977292 4 Q9H2U1 1 +B cell activation involved in immune response 0.3002144745866905 0.1577291574294309 0.8746702237753579 1.0 0.9855782802977292 18 Q96FZ2,Q9UQ84,O96028,Q96FV9 4 +Positive regulation of calcium ion transmembrane transporter activity 0.3385731574172815 0.1550272416959265 0.8767998411607261 1.0 0.9855782802977292 10 Q96GC9 1 +Somite rostral caudal axis specification 0.3130105017502907 0.1549797966360757 0.8768372448000827 1.0 0.9855782802977292 2 Q15363 1 +Positive regulation of chromosome separation 0.3343072738223942 0.1538035936886138 0.877764600201842 1.0 0.9861139028461714 11 Q9UJX4,Q14674,Q96MF7,Q13042 4 +Response to interferon gamma 0.2875551955967507 0.1527783756476779 0.8785730512522036 1.0 0.986245059678186 23 P08670,O60506,Q16543 3 +Exocrine system development 0.3798023543881256 0.1525410012674143 0.8787602544625459 1.0 0.986245059678186 6 Q5T9L3 1 +Positive regulation of membrane protein ectodomain proteolysis 0.3501604902246951 0.1522482512594724 0.8789911385069966 1.0 0.986245059678186 3 Q9Y5X1,O43847 2 +Regulation of immunoglobulin production 0.3104119404936525 0.152138473872276 0.8790777196288664 1.0 0.986245059678186 16 Q99623,Q96FZ2,O96028,Q96FV9 4 +Regulation of actin cytoskeleton reorganization 0.3374315248206977 0.1511688484732317 0.8798425231784854 1.0 0.9869276302730292 10 O14786,Q9UQB8 2 +Regulation of endoplasmic reticulum tubular network organization 0.3791298196841934 0.150787800953139 0.8801431096604646 1.0 0.9870960665855356 6 P57088 1 +B cell mediated immunity 0.2919344514413256 0.1476487653198955 0.8826199676754425 1.0 0.9888558580015004 19 Q07021,Q96QE3,Q9UQ84,O96028,Q96FV9,Q96FZ2 6 +Cellular component disassembly involved in execution phase of apoptosis 0.3358471489558382 0.1458690644500434 0.8840247533245209 1.0 0.9899266947637384 10 Q96JB5 1 +Dendritic cell cytokine production 0.3770443925233817 0.1454044172893482 0.8843915772374971 1.0 0.9899995786135204 6 Q9NR30,Q9H2U1,Q7Z434,Q9NY93,P16885 5 +Positive regulation of dendritic cell cytokine production 0.3770443925233817 0.1454044172893482 0.8843915772374971 1.0 0.9899995786135204 6 Q9NR30,Q9H2U1,Q7Z434,Q9NY93,P16885 5 +Regulation of nervous system development 0.2458830611248321 0.1434128061274768 0.8859641696916016 1.0 0.9908263413765472 68 O75746,P30536,Q15154,Q9H2U1,Q13641,Q9UBS4,Q16706,P42345,P27695,O14786,Q9NQC3,O94813,O14744,P55209,Q9Y4G8,Q9UQB8,Q7L576,Q96G23 18 +Positive regulation of interferon gamma production 0.3813794054953051 0.14338443028199 0.8859865787515198 1.0 0.9908263413765472 5 P04439 1 +Intraciliary transport 0.3384267449402601 0.1433217075696133 0.8860361126482139 1.0 0.9908263413765472 9 Q15154,Q9Y366,A0AVF1 3 +R loop disassembly 0.3852889667250501 0.1420680784425834 0.8870262320982385 1.0 0.990916777491093 4 Q9NR30,P78362,Q9NY93 3 +Tubulin deacetylation 0.3588492989551322 0.1419701351462551 0.8871035954081405 1.0 0.990916777491093 7 P54646,P49354 2 +Dna catabolic process 0.3305001937806395 0.1405426847954872 0.888231229550815 1.0 0.9914225766818248 11 Q9H0D6,P27695,Q07812,Q13315,O95831 5 +Negative regulation of cell substrate adhesion 0.3251470450655295 0.1362672946854793 0.8916099777369304 1.0 0.9936726688026049 12 O14936,P61586,O43707 3 +Trna methylation 0.306235575557427 0.1342159929816472 0.8932317797637117 1.0 0.994244551265125 16 Q7Z2T5,Q9Y2Z2,O75648,Q9NNW5 4 +Stress granule assembly 0.3008165771426796 0.1338168006537454 0.8935474416842326 1.0 0.994244551265125 17 Q14011,P31483,P54646,Q14157,Q9Y5A9 5 +Cardiac ventricle morphogenesis 0.355536079462452 0.1329360491105528 0.8942439568377203 1.0 0.994506499196334 7 P15924,Q12948,P09493,Q99959,P49840,Q9P2D1 6 +Myeloid dendritic cell cytokine production 0.3769343065693482 0.1328292977793605 0.8943283833827442 1.0 0.994506499196334 5 Q9NR30,Q9H2U1,Q9NY93,Q7Z434 4 +Positive regulation of myeloid leukocyte mediated immunity 0.3769343065693482 0.1328292977793605 0.8943283833827442 1.0 0.994506499196334 5 Q9NR30,Q9H2U1,Q9NY93,Q7Z434 4 +Positive regulation of cyclin dependent protein kinase activity 0.3809106830122661 0.1322573962938325 0.8947807041150728 1.0 0.994723726634626 4 O75832,P14635,P08238 3 +Response to endogenous stimulus 0.2231688004785746 0.132108595001078 0.8948983976735565 1.0 0.994723726634626 307 Q99623,P30536,O75874,P20020,O00560,Q92896,Q92974,P35613,Q14103,Q9UQB8,P04083,Q15392,P04062,Q14457,O75844,O95831,O14737,P43490,Q99729,P16278,P08574,P14625,P46108,Q7L576,P09601,Q9BSK2,Q15043,Q9BZF1,P54646,P05067,P61586,P42785,O14744,Q9H7B4,P08670,O43865,P42345,O15173,P46934,P16435,Q15057,Q96PK6,O15118,Q8TBX8,Q8NEM2,Q96HY6,P35610 47 +Plasma membrane organization 0.2798587791561205 0.1319879809281533 0.8949937984044694 1.0 0.994723726634626 25 Q4KMQ2,Q9UQB8,Q96GC9 3 +Negative regulation of canonical wnt signaling pathway 0.3151487374756682 0.1316240376209383 0.8952816716708476 1.0 0.994723726634626 14 Q13641,P48729 2 +Positive regulation of dendritic spine development 0.3235895355447546 0.1307644362017135 0.8959616571671625 1.0 0.9951005751362004 12 Q9UQB8 1 +Cell proliferation in forebrain 0.3801217113240049 0.1305237523208176 0.8961520632520397 1.0 0.9951005751362004 4 Q15154 1 +Negative regulation of small gtpase mediated signal transduction 0.3189939927969836 0.1302368048995685 0.8963790764446937 1.0 0.9951005751362004 13 O95630,Q9NUQ9,O94813 3 +Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway 0.3794512551080039 0.1290587731255923 0.8973111434000058 1.0 0.9957263776861844 4 P49840,P04899,P23634 3 +Positive regulation of defense response to virus by host 0.3700350467289827 0.1279028988469325 0.8982258169428454 1.0 0.9963079463791332 6 Q7Z434,P42224,Q96ST3,O94826,P07900 5 +Response to x ray 0.309015207275582 0.1254396966954933 0.9001754628710823 1.0 0.9977168917168344 15 Q13315,P04083 2 +Somatic diversification of immune receptors via somatic mutation 0.3523599373077301 0.1244929926142774 0.900924948303583 1.0 0.9979523144443132 7 Q9UQ84 1 +Positive regulation of cilium assembly 0.36791709589699 0.1227958741183534 0.9022687415110252 1.0 0.9984720414010008 6 P42858,Q9P2S5 2 +Mrna splice site selection 0.2847871091552645 0.1222357206382885 0.902712337579159 1.0 0.9985531983557572 21 O95391,Q9UHX1 2 +Regulation of peptidyl lysine acetylation 0.2815283528165349 0.1200578668713309 0.9044373082727089 1.0 0.9993126143939242 23 O75844 1 +Positive regulation of stress activated protein kinase signaling cascade 0.3160184470338518 0.1194437348095463 0.9049238139124676 1.0 0.9995360819586748 13 O00560,P05067 2 +Interferon gamma production 0.3502778485201929 0.1190744428402267 0.9052163783239308 1.0 0.9995360819586748 7 Q07021,P04439,Q9NUQ9 3 +Cell aging 0.261182820750524 0.1186143756090211 0.9055808756718416 1.0 0.9997344727723124 32 O75844,P67809,Q13315,Q13535,O60313 5 +Negative regulation of protein serine threonine kinase activity 0.2856832132423728 0.1175092947799015 0.9064564789053232 1.0 1.0 19 Q96JB5,P04062 2 +Response to monosaccharide 0.2503161117005598 0.1132349448816959 0.9098442918138074 1.0 1.0 39 Q15120,P54646,P61586,P49770,Q15907,P22059,Q8N5M9,Q15043 8 +Ear development 0.2784321709761732 0.112853743571134 0.9101465092480538 1.0 1.0 24 O75569,Q9Y6M7,P42892,P54802 4 +Tissue remodeling 0.2838623902574171 0.112608937414777 0.9103405990922292 1.0 1.0 20 O14773 1 +Regulation of mitotic nuclear division 0.2388578488705288 0.1114112946769856 0.9112902039643204 1.0 1.0 46 Q9UJX4,Q14674,Q96GD4,O43683,Q9UJX2,O14965,O43670,Q96DY7,O14744,Q13042,Q13315,O14777,P53350,Q96MF7 14 +Regulation of rna export from nucleus 0.324157005621472 0.1087781860030487 0.9133784261800516 1.0 1.0 10 Q07666,Q08211 2 +Exocytosis 0.2386875404473228 0.1084795119534487 0.9136153316910602 1.0 1.0 72 O00560,Q13277,Q06787,P16615,Q9BRK5,Q4J6C6,P04083,Q15907,P09601 9 +Regulation of mitotic sister chromatid segregation 0.2772290816606866 0.1063993872413075 0.9152654792295132 1.0 1.0 24 Q96GD4,O43683,Q00839,O43670,Q13315,O14777,P53350,Q14457 8 +Positive regulation of mitotic cell cycle phase transition 0.2493405376232511 0.1056868835114326 0.9158307875035988 1.0 1.0 39 Q99623,Q14674,Q9UJX4,Q9UJX2,P27695,Q96DY7,P05067,Q13042,P31350,P04083,Q96MF7 11 +Response to electrical stimulus 0.3604725681973284 0.1055191941167228 0.9159638403076628 1.0 1.0 6 Q14103 1 +Negative regulation of tor signaling 0.3228151831491681 0.104751555195091 0.9165729518259712 1.0 1.0 10 P54646 1 +Regulation of mononuclear cell migration 0.2989746082853428 0.1044828294530938 0.9167861938063386 1.0 1.0 16 Q4KMQ2,P61586,P05067 3 +Regulation of cellular response to insulin stimulus 0.2931774614411861 0.1011921689054321 0.9193979131173527 1.0 1.0 17 P20020,Q9BZF1,Q9Y5X3,Q8TBX8,Q9HCD5 5 +Cell fate commitment 0.2802478008392021 0.0999189598227129 0.9204086639162156 1.0 1.0 21 P42345,O14786,P61586,Q92974,Q07820 5 +Regulation of t cell proliferation 0.2873491240447738 0.0990406714383108 0.9211059776951322 1.0 1.0 18 P04439,P04083 2 +Regulation of metaphase plate congression 0.3573288687431605 0.0985407042550188 0.9215029518985944 1.0 1.0 6 Q00839,Q14457 2 +Cellular response to light stimulus 0.2580796826708952 0.097648630956166 0.9222113070791952 1.0 1.0 32 P46934,Q06787,Q13535,P27544,Q96K76 5 +Protein demethylation 0.3229085552356151 0.0972530793044747 0.9225254165893172 1.0 1.0 9 Q8NB78 1 +Regulation of amyloid precursor protein catabolic process 0.3094190577318107 0.0964688849474819 0.923148184859112 1.0 1.0 13 P42574,P27695,O95197,Q9NQC3 4 +Pancreas development 0.3169230728530382 0.096468038277084 0.9231488572682848 1.0 1.0 11 P04083,Q5T9L3 2 +Perk mediated unfolded protein response 0.3597886848443158 0.095419465684711 0.9239816552406996 1.0 1.0 5 P57088 1 +Integrated stress response signaling 0.3597886848443158 0.095419465684711 0.9239816552406996 1.0 1.0 5 P57088 1 +Muscle organ morphogenesis 0.355432242990669 0.0944219869247793 0.9247739507890916 1.0 1.0 6 P15924,Q12948,P09493,Q99959,Q9P2D1 5 +Cardiac muscle tissue morphogenesis 0.355432242990669 0.0944219869247793 0.9247739507890916 1.0 1.0 6 P15924,Q12948,P09493,Q99959,Q9P2D1 5 +Ventricular cardiac muscle tissue morphogenesis 0.355432242990669 0.0944219869247793 0.9247739507890916 1.0 1.0 6 P15924,Q12948,P09493,Q99959,Q9P2D1 5 +Mrna modification 0.3125704913425778 0.0938338868774365 0.925241112596713 1.0 1.0 12 Q96FX7,Q99729,Q96PZ0,Q9UBS4 4 +Negative regulation of cysteine type endopeptidase activity 0.272836347028628 0.0929946687011319 0.9259077966300576 1.0 1.0 25 P16435,Q15392,Q96K76 3 +Regulation of heart rate 0.295945173998539 0.0926277256868423 0.9261993165222367 1.0 1.0 16 Q9HD47 1 +Negative regulation of intracellular signal transduction 0.2323357135084508 0.0926090148152413 0.92621418174274 1.0 1.0 108 P42345,Q96K76,Q10713,O76024,O95630,P54646,P61586,Q92974,P45880,P57105,Q13315,O95881,Q96JB5,Q9NUQ9,Q9P0J0,O60313,P04062,O43657 18 +Meiotic cell cycle phase transition 0.3610699913399905 0.0918652006149403 0.9268051403966088 1.0 1.0 4 O14777 1 +Positive regulation of mitochondrial fission 0.3390587316851196 0.0914779850678314 0.9271127982524784 1.0 1.0 7 Q9NQG6 1 +Humoral immune response 0.3114479158953816 0.0902716766371731 0.928071327006664 1.0 1.0 12 Q99623,Q07021,Q9UQ84,P04439 4 +Purine nucleotide catabolic process 0.3112594732412186 0.0896773763106868 0.9285435945796046 1.0 1.0 12 A8MXV4,P35610,P49902 3 +Positive regulation of phagocytosis 0.3199012013976725 0.0890356833201102 0.9290535515330324 1.0 1.0 9 Q4KMQ2,Q08431 2 +Dosage compensation 0.3143710091288584 0.0887579298779968 0.9292742927705042 1.0 1.0 11 Q15022,Q00839 2 +Regulation of cardiac muscle contraction 0.2992558989133478 0.0883185000890137 0.9296235354663008 1.0 1.0 15 Q9HD47 1 +Maintenance of blood brain barrier 0.3376762488202302 0.0882655954161484 0.9296655830773768 1.0 1.0 7 Q16625 1 +Regulation of protein secretion 0.2353954883374088 0.0881857237148494 0.9297290639331872 1.0 1.0 45 Q96KC8,Q32P28,Q9H4A6,P55011,P00367,P53985,Q16850,Q16836,P22059,Q8N5M9,Q5T9L3 11 +Modulation by host of viral genome replication 0.3370810587686337 0.0868953615350962 0.9307546865340616 1.0 1.0 7 Q06787 1 +Embryonic hemopoiesis 0.3577944267775756 0.0858410725531017 0.9315927557845792 1.0 1.0 4 Q03164 1 +Response to topologically incorrect protein 0.24021170773693 0.0842736603414771 0.9328388538912352 1.0 1.0 54 P46379,P57088,O76024,Q96HY6,Q9BUN8,Q8TCJ2,Q9UBN7,Q15629,Q6NTF9,Q9Y4P3,Q96JB5,Q13438 12 +Regulation of mitochondrial dna replication 0.3566841798015245 0.0838406291043995 0.933183144365936 1.0 1.0 4 Q9UJZ1,Q14249,Q04837 3 +Cellular response to unfolded protein 0.2573261939117301 0.0836927255242862 0.9333007410447948 1.0 1.0 31 P57088,O76024,Q9BUN8,Q96JB5,Q6NTF9,Q9Y4P3,Q96HY6 7 +Cytokine production 0.2308517191346049 0.083127849683127 0.9337498816330788 1.0 1.0 101 P30536,P20020,O60684,P31483,P05067,P01889,P04439,P04083,Q8IV08,P09601,P04062 11 +Regulation of translation in response to stress 0.3123744628366848 0.0828550290930879 0.9339668126165808 1.0 1.0 11 P51812,Q15418,Q9BWF3 3 +Ectodermal placode development 0.3560588039751066 0.0827230508886693 0.934071755729852 1.0 1.0 4 O14786,Q13547 2 +I kappab kinase nf kappab signaling 0.2416356650798447 0.082247356925817 0.9344500155997212 1.0 1.0 58 Q9P035,Q86UE4,P61586,Q8TB61,Q96HY6,P09601,O43657 7 +Positive regulation of protein modification by small protein conjugation or removal 0.239187777673371 0.0820575233776173 0.9346009705968656 1.0 1.0 42 Q9BTE7,O76024,Q92564,Q9BUN8,Q96JB5,Q8TAF3 6 +Positive regulation of protein tyrosine kinase activity 0.3529927007299325 0.0820568093448977 0.934601538397718 1.0 1.0 5 Q13432,P18031,Q13177,Q8IZP0 4 +Positive regulation of erbb signaling pathway 0.3493081592158774 0.0815939123218279 0.9349696424174792 1.0 1.0 6 Q9NQC3 1 +Mammary gland epithelium development 0.3344573458137369 0.0809468234479941 0.9354842423875568 1.0 1.0 7 Q9NQC3 1 +Homologous recombination 0.3143274853801182 0.0804041042985224 0.9359158627174948 1.0 1.0 10 Q92878,O60216,Q9H1E3,P11388,Q02880,Q9BXW9,Q15645,Q8IWV8,Q13315 9 +Telomere capping 0.2970072686066619 0.0802260922553958 0.936057438422902 1.0 1.0 15 Q13315,P78527,Q14103 3 +Negative regulation of cell division 0.3168952436533504 0.0800232423697785 0.9362187705094918 1.0 1.0 3 Q96GD4,Q9UN37 2 +T cell mediated immunity 0.310686373523886 0.0779527875106598 0.937865608761034 1.0 1.0 11 P01889,P04439 2 +Negative regulation of response to external stimulus 0.2391031516822453 0.0776843160334204 0.9380791703916826 1.0 1.0 53 Q96J02,P80303,P55011,O94813,O14786,O14936,P01889,P46108,P04439,Q6YHK3,Q96G23,P04062,O43657 13 +Positive regulation of double strand break repair via homologous recombination 0.2761885053519718 0.0771236629551773 0.9385251687454566 1.0 1.0 20 Q8TAF3,P35637,Q7Z4V5 3 +Response to misfolded protein 0.3131050689617811 0.0770584972833451 0.9385770091551217 1.0 1.0 10 P46379,Q9BUN8 2 +Icosanoid biosynthetic process 0.3023596878606291 0.0733926334731156 0.9414936794248884 1.0 1.0 13 Q9NP80,P04083,Q9H7Z7 3 +Pigment biosynthetic process 0.273530987783525 0.0730990380784317 0.9417273071145617 1.0 1.0 22 P30536,P36551,Q7KZN9,O00264,Q9Y4G8,P22830,P34896 7 +Regulation of membrane protein ectodomain proteolysis 0.3502626970227733 0.0726807120998197 0.9420601974640344 1.0 1.0 4 Q9Y5X1,O43847,Q13464 3 +Ribonucleoprotein complex localization 0.3304119193689702 0.0720681614887623 0.9425476637697436 1.0 1.0 7 Q08J23,Q8WWY3,Q9BYW2,Q9ULX6,P12270,Q9BVS4 6 +Regulation of receptor catabolic process 0.3493870402802164 0.0712129541695355 0.94322827165684 1.0 1.0 4 P18031,Q96J02,P07355 3 +Positive regulation of cell cell adhesion 0.2645112186712104 0.0710214986775379 0.9433806452232918 1.0 1.0 27 P04439,P30825,P61586,P04083 4 +Negative regulation of transport 0.2254243546752557 0.0709189001625653 0.9434623010942668 1.0 1.0 84 P46934,P21796,Q06787,P05067,Q16850,Q96PU5,P04083,P09601 8 +Regulation of heterotypic cell cell adhesion 0.3116428362999831 0.0706712178879954 0.9436594283421352 1.0 1.0 3 O75955,Q14254 2 +Regulation of rrna processing 0.3102339181286587 0.0693609196178431 0.9447023355960702 1.0 1.0 10 Q8IWA0,Q96DE0,Q15061,Q9UNQ2,Q9H583,Q8TED0,Q9BRS2,Q9BVS4,Q9Y5A9 9 +Regulation of skeletal muscle tissue development 0.3482194979568074 0.0692760482397865 0.9447698906603252 1.0 1.0 4 P35222,O75955,Q96TA1 3 +Cellular response to reactive oxygen species 0.251888687919584 0.0683435666135363 0.9455121440378856 1.0 1.0 34 Q99720,P00374,P04083,Q14457 4 +Regulation of neurogenesis 0.2411516924185764 0.068106967199585 0.945700484214174 1.0 1.0 61 P30536,Q15154,P42345,Q16706,Q9NQC3,O14786,O14744,P55209,Q9UQB8,Q7L576,Q96G23 11 +Import into nucleus 0.2403116052694222 0.0665951327513426 0.9469040206473232 1.0 1.0 66 Q99623,O60684,O15397,Q7Z3B4,Q99567,Q9HD47,Q92973,P52294,Q5SRE5,Q8N1F7 10 +Reticulophagy 0.3414552793633095 0.066197368332503 0.9472206919472984 1.0 1.0 6 Q96HY6,O94874,Q9Y6I9 3 +Cellular response to dsrna 0.3267569821465731 0.0643523797553201 0.9486896468358664 1.0 1.0 7 Q08211,Q9NUD5 2 +Pro b cell differentiation 0.3063904289466111 0.0618705139322098 0.9506659489703366 1.0 1.0 3 P78527,O43809 2 +Lymphoid progenitor cell differentiation 0.3063904289466111 0.0618705139322098 0.9506659489703366 1.0 1.0 3 P78527,O43809 2 +Regulation of nucleobase containing compound transport 0.3048137103796119 0.0615350018138959 0.9509331397953208 1.0 1.0 11 Q07666,Q08211 2 +Carbohydrate transmembrane transport 0.2915258376170648 0.0612385955216961 0.95116919261593 1.0 1.0 15 O00186,P52789,Q9BZF1,P11166,Q99523,Q16625 6 +Response to fungus 0.3247212447247278 0.060180560121813 0.9520118284238412 1.0 1.0 7 P46108 1 +Coronary vasculature morphogenesis 0.3414637653387118 0.0585174595021509 0.9533364556529328 1.0 1.0 4 O14786 1 +Positive regulation of ubiquitin protein ligase activity 0.3409897494830382 0.0577911693993609 0.9539149722227416 1.0 1.0 4 P53350 1 +Regulation of protein acetylation 0.2641027487161391 0.0572509977271578 0.9543452544338138 1.0 1.0 26 O75844 1 +Negative regulation of hormone secretion 0.3364901716586509 0.0570712431057668 0.954488443751638 1.0 1.0 6 Q16836,Q8N5M9 2 +Negative regulation of peptide secretion 0.3364901716586509 0.0570712431057668 0.954488443751638 1.0 1.0 6 Q16836,Q8N5M9 2 +Regulation of oligodendrocyte differentiation 0.3078032311782048 0.055452447224691 0.9557780132371204 1.0 1.0 8 P42345 1 +Positive regulation of peptidyl serine phosphorylation 0.2702951764203866 0.0542056544688573 0.956771315695361 1.0 1.0 21 O95429,P05067,Q14012,Q9H7B4,Q9UBN7,P07900,P23634 7 +Poly a plus mrna export from nucleus 0.3018426440479594 0.0536073122707965 0.957248030541766 1.0 1.0 11 O60318,Q8NI27,Q9UBU9,Q9NPA8,Q86U42,Q8WUM0,Q5JVF3,Q9BY77,Q8N1F7,P82979 10 +Response to nerve growth factor 0.2890303339751597 0.0529450828128912 0.957775663855856 1.0 1.0 15 Q15057,P05067,P46108,Q9Y4G8,Q99523 5 +Mrna export from nucleus 0.2376582527666347 0.0513912231628002 0.9590137784346908 1.0 1.0 41 Q96FV9,Q12769,Q99567,Q96MU7,Q9ULX6,Q8N1F7,P22626 7 +Protein acetylation 0.2394677145365766 0.0507079598842464 0.9595582337408086 1.0 1.0 65 O75844,P16435,P54646,Q86UY6,O14929,Q9Y6J9 6 +Camera type eye development 0.2418298922099233 0.0499052565019305 0.9601978884423824 1.0 1.0 39 P20020,Q99797,O14786,P08670,O75569,P54802,Q8NF37 7 +Skeletal muscle cell differentiation 0.3047797124488968 0.0488996624638006 0.9609992578569012 1.0 1.0 8 P50402,P17844,Q9BYT8 3 +Positive regulation of leukocyte degranulation 0.3348779990728801 0.0487590343311241 0.961111329186884 1.0 1.0 4 P11279 1 +Insulin secretion 0.2550728091142016 0.046083558713473 0.963243650331454 1.0 1.0 29 P04049,O00186,P00367,P53985,O95563,P04083,Q15907,Q16836,P40939,P22059,Q8N5M9 11 +Regulation of epithelial cell apoptotic process 0.29320916828498 0.0458368566261328 0.9634402823309662 1.0 1.0 13 P09601 1 +Positive regulation of organelle organization 0.2280776999158172 0.0452809779742769 0.963883349262407 1.0 1.0 170 Q9P2W9,O14786,P21796,O00560,Q13042,Q13315,Q14103,Q9UQB8,P04083,Q14457,Q8N2A8,O14737,Q9P2S5,Q7L576,P22059,P42858,Q9Y2A7,P61586,Q13535,P22626,P12235,Q16625,Q96A26,P42345,O15260,Q9NQG6,Q8TBX8,P27544,Q96MF7 29 +Macromolecule deacylation 0.2342383801919297 0.0435452946813379 0.9652668588129424 1.0 1.0 42 P49354,P23246,P54646,Q96PK6,Q9UBN7,P50897,Q9NUJ1 7 +Regulation of mrna export from nucleus 0.3302189781021942 0.0433175066352913 0.9654484360434974 1.0 1.0 5 Q9ULX6,Q9BYW2,P12270,Q08J23 4 +Mitochondrion localization 0.2677576616469869 0.0432818635958897 0.965476848427187 1.0 1.0 21 Q9UBN7,Q8IWA4,O60313,Q9UBK9,O75153 5 +Regulation of cellular response to stress 0.2275707204929068 0.0428609891751519 0.9658123462836316 1.0 1.0 172 P46379,P61978,P57088,Q9NP80,P67809,P78318,O00560,Q92974,Q9UNS1,Q13315,Q9UBN7,O95202,Q96FV9,Q8TAF3,Q7Z4V5,O75844,Q96J02,Q969S3,P78527,O95881,P23246,Q06787,P00374,P05067,Q96QE3,Q13535,P51114,O96028,P42345,P51116,O76024,P35637,Q08211,Q07820,Q96HY6,O60313,Q96G23,Q96K76 38 +Positive regulation of myelination 0.2931633307422717 0.0420974581029651 0.9664210065162796 1.0 1.0 3 O75746 1 +Purine containing compound catabolic process 0.2918729069656779 0.0420378037143048 0.9664685617344552 1.0 1.0 13 A8MXV4,P35610,P49902 3 +Protein quality control for misfolded or incompletely synthesized proteins 0.2918398468698243 0.0419445418049559 0.9665429083969108 1.0 1.0 13 P46379,Q9BUN8,Q9UBN7 3 +Execution phase of apoptosis 0.2772889048037676 0.0404479263787912 0.9677360217639046 1.0 1.0 17 P42574,Q7L7X3,Q07812,Q8IXJ6,Q96JB5,O95831 6 +Regulation of calcium mediated signaling 0.3005797036490743 0.0401721281560673 0.9679558981960096 1.0 1.0 8 P42345 1 +Insulin secretion involved in cellular response to glucose stimulus 0.295205594495844 0.0368186083191627 0.9706296368143724 1.0 1.0 11 Q8N5M9,P22059,O95563,Q15907 4 +Response to hydroxyurea 0.3118690173483744 0.0359055680822141 0.9713576560443836 1.0 1.0 7 Q06787 1 +Nuclear migration 0.289648776603173 0.0358421520395351 0.9714082221776312 1.0 1.0 13 O94901,Q15154,Q9UH99 3 +Regulation of histone phosphorylation 0.2984142153489979 0.0358418738877451 0.9714084439681429 1.0 1.0 8 Q13315,Q06787 2 +Actin cytoskeleton reorganization 0.2598734743016153 0.0357232958375704 0.971502995012926 1.0 1.0 26 O14786,Q9UQB8,P61586,P04083 4 +Skeletal muscle organ development 0.2651641625471218 0.0353661525268717 0.97178777418927 1.0 1.0 22 Q9BYT8,P51114,P61586 3 +Regulation of phosphatase activity 0.2664771471509444 0.0351900088597113 0.97192822907333 1.0 1.0 19 P42345,P14625,Q96JB5 3 +Regulation of golgi organization 0.2973125212543014 0.0348315092392434 0.9722140951297022 1.0 1.0 9 Q9P2W9 1 +Granulocyte migration 0.2656242681891985 0.0319111578453715 0.9745429004985364 1.0 1.0 19 P78310,O94813,P35613,P04083,Q8N5M9 5 +Rrna modification 0.2822840409956064 0.0316356207259945 0.9747626363663398 1.0 1.0 15 Q8WVM0,Q96HR8,O43709,O60832,Q9UNQ2,Q96P11,P46087,Q6P087,Q9NY12,Q9H0A0,P22087,Q9H5Q4,Q92979,Q8IY81 14 +Neural crest cell migration 0.3213660245183958 0.0309361158663328 0.9753204874020384 1.0 1.0 4 O14786,P08133,P60953 3 +Golgi to vacuole transport 0.3088861349286756 0.03077549629745 0.9754485822832224 1.0 1.0 7 Q99523 1 +Auditory receptor cell development 0.3211771909653045 0.0304605834545891 0.9756997286295332 1.0 1.0 5 Q9Y6M7 1 +Regulation of response to external stimulus 0.2282663653891385 0.0298403909258271 0.9761943457976014 1.0 1.0 142 Q13641,P80303,O14786,P11279,Q13315,Q8NCG7,P04083,P07900,P04062,O75844,Q9NUD5,Q4KMQ2,Q96J02,Q13277,P78527,P46108,Q9NZ08,O43657,P55011,P23246,P43243,O15360,P05067,Q9NUQ9,Q16543,O14936,Q96PK6,P01889,P04439,Q08211,Q96G23 31 +Negative regulation of b cell activation 0.319543294599029 0.0294211551896133 0.9765287007052794 1.0 1.0 6 Q13315,Q96FV9 2 +Negative regulation of dna replication 0.2917980838569545 0.0286931336149561 0.9771093326961492 1.0 1.0 11 Q13535 1 +Cellular amino acid biosynthetic process 0.2447673065546891 0.0286060070702455 0.9771788210971692 1.0 1.0 35 P00374,P00367,P34896,Q13126,Q9NRN7,A1L0T0,Q99707,O60568 8 +Mitochondrial dna metabolic process 0.3067484662576609 0.0272141507564786 0.9782889292151444 1.0 1.0 7 Q9BQP7,P04637,P36776,P09874,Q14249,P49916 6 +Carbohydrate transport 0.2690826440047308 0.0270985850287701 0.9783811033309776 1.0 1.0 18 P52789,Q9BZF1,L0R6Q1,Q99523,Q16625 5 +Positive regulation of reproductive process 0.2922999072007126 0.024232768911614 0.9806669399878613 1.0 1.0 8 Q07021,O14965,Q9H6S0,Q8IXJ6,Q8IY37 5 +Cell fate determination 0.3155283129013494 0.0241213099983768 0.9807558453461628 1.0 1.0 4 P35222,Q07820,P60953 3 +Cdp diacylglycerol metabolic process 0.31537380062009 0.0234303835659415 0.9813069690736668 1.0 1.0 6 Q9NUQ2,Q96BW9 2 +Copi coated vesicle budding 0.3146477694019471 0.0224192226016461 0.9821135467862768 1.0 1.0 6 Q9BVK6,P49755,Q15363 3 +Regulation of mitotic recombination 0.3137769994162354 0.0221777668180178 0.9823061527376882 1.0 1.0 4 Q92878,Q15554,P18074 3 +Negative regulation of axonogenesis 0.3147146026398348 0.0221173221164057 0.9823543688051076 1.0 1.0 5 Q9NQC3 1 +Positive regulation of cell cycle g1 s phase transition 0.2619938176750151 0.0219578916445546 0.9824815450312788 1.0 1.0 22 Q99623,Q96DY7,P31350,P04083,Q96HY6 5 +Granulocyte chemotaxis 0.2755460687609772 0.0216017282518761 0.9827656549087288 1.0 1.0 16 P35613,P04083,P78310,O94813 4 +Regulation of b cell proliferation 0.3015933562043491 0.019016768484236 0.9848277285125904 1.0 1.0 7 Q13315,Q96QE3 2 +Regulation of phagocytosis 0.2708774593550567 0.0187631531293237 0.9850300481879676 1.0 1.0 17 Q4KMQ2 1 +Regulation of leukocyte apoptotic process 0.2869622069722748 0.0177344893239526 0.9858506664680436 1.0 1.0 11 Q9Y4G8,P04083 2 +Protein destabilization 0.2849261691300996 0.0171857224990819 0.9862884523038444 1.0 1.0 12 P42858,Q9BUN8,P78527,Q9UBN7,P53350 5 +Synaptic vesicle cytoskeletal transport 0.3107476635514044 0.017148004378601 0.9863185425756906 1.0 1.0 6 O95295,O00203,P78537,Q92572,Q9Y2T2 5 +Leukotriene biosynthetic process 0.2716661803326635 0.0168593117908118 0.9865488526369716 1.0 1.0 3 O14880,Q99735 2 +Protoporphyrinogen ix metabolic process 0.3097767653570934 0.0162043637619349 0.9870713541428602 1.0 1.0 5 P22830 1 +Regulation of response to biotic stimulus 0.2309194296804911 0.0153570721233018 0.987747310867256 1.0 1.0 71 O75844,Q9NUD5,Q96J02,Q16543,P23246,P43243,Q07021,P11279,Q96PK6,P78527,P01889,P46108,P04439,Q08211,Q9NZ08,O43657,P07900,Q9Y5A9 18 +Negative regulation of muscle tissue development 0.3064798598949273 0.0145677470404263 0.9883770306551964 1.0 1.0 4 Q8IXJ6,O94966,Q9NQ29 3 +Autophagy of nucleus 0.3050204319906664 0.0131382848248261 0.989517466956624 1.0 1.0 4 Q9Y4P8,O95352,Q7Z3C6 3 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.3070814240066559 0.0124366890803224 0.9900772135909032 1.0 1.0 6 P61978 1 +Citrulline biosynthetic process 0.3029828493675215 0.011192982932339 0.9910694782029084 1.0 1.0 4 P54886 1 +Citrulline metabolic process 0.3029828493675215 0.011192982932339 0.9910694782029084 1.0 1.0 4 P54886 1 +Notch signaling pathway 0.2599557845114028 0.0107747377713513 0.9914031694273316 1.0 1.0 20 P05067,P57105 2 +Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna 0.3057258134831808 0.0107536460850378 0.991419997183276 1.0 1.0 6 P78316,Q86U38 2 +Brown fat cell differentiation 0.2957616592491476 0.0103990470553711 0.9917029104491856 1.0 1.0 7 Q6IAN0 1 +Dna integrity checkpoint signaling 0.2280416057420188 0.0089631105514101 0.9928485682289026 1.0 1.0 48 Q6NUQ1,Q9Y619,Q9UNS1,Q13315,Q13535,P53350,Q96JB5 7 +Positive regulation of glycoprotein metabolic process 0.2826999980103931 0.0078140086375214 0.9937653865964696 1.0 1.0 8 P35610 1 +Positive regulation of membrane potential 0.2991827203736207 0.0077194613437244 0.9938408221471756 1.0 1.0 4 Q9UJZ1,Q12955,Q8IWA4 3 +Inner ear auditory receptor cell differentiation 0.3030892594432435 0.0075702727150992 0.9939598539720942 1.0 1.0 6 Q9Y6M7 1 +Ear morphogenesis 0.2764340185638552 0.0072742367449958 0.9941960499951265 1.0 1.0 14 P54802 1 +Epigenetic maintenance of chromatin in transcription competent conformation 0.3022780373831851 0.0066145142259229 0.9947224197058916 1.0 1.0 6 O75367,Q969T9,O14757,Q96GM5,O75151 5 +Cellular response to organic cyclic compound 0.2259786747726007 0.0041284841837724 0.9967059555677436 1.0 1.0 117 Q99623,P20020,Q8TB36,P27695,P17844,P53985,Q14103,Q9UBN7,P04083,Q9NUD5,O95831,P14625,O75955,P23634,P42574,Q969T9,P05067,P61586,O14744,Q9H7B4,Q9Y4G8,Q92542,O15173,Q00839,Q9H4A6,P05023,P46934,Q92841,O15118,O94874,Q08211,Q96HY6 32 +Transcription elongation from rna polymerase i promoter 0.2927612375948697 0.0022938394162478 0.998169782549824 1.0 1.0 4 Q9GZS1,P18074,P19447 3 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.2796293534513482 0.0012891104786364 0.998971438936805 1.0 1.0 10 P61978,Q96K76 2 +Negative regulation of dna templated transcription elongation 0.2889981564620987 0.0012532545365833 0.999000047816266 1.0 1.0 7 O14776,Q00839 2 +Histone deubiquitination 0.2789380246962474 0.001019321701156 0.9991866990929952 1.0 1.0 11 Q9Y6J9,Q99496,Q9Y4A5,Q9BWJ5 4 +Positive regulation of focal adhesion assembly 0.2791720691430883 0.0008182732268623 0.9993471124986272 1.0 1.0 9 O14786 1 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..82fcf73c0645168ebadbe5fcf71093bb78a72271 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of janus kinase activity", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activation of store operated calcium channel activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Acylglycerol transport", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult heart development", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in coronary vascular morphogenesis", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in heart morphogenesis", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular node development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone mineralization involved in bone maturation", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "Bundle of his cell to purkinje myocyte signaling", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein deglutamylation", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac right ventricle morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell differentiation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nicotine", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cochlea development", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common bile duct development", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Copulation", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial nerve morphogenesis", "Cranial nerve structural organization", "Cranial skeletal system development", "Craniofacial suture morphogenesis", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of stimulus involved in sensory perception of pain", "Detection of temperature stimulus", "Detection of temperature stimulus involved in sensory perception", "Detection of temperature stimulus involved in sensory perception of pain", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal cell differentiation", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of left right asymmetry", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eyelid development in camera type eye", "Face development", "Facial nerve morphogenesis", "Facial nerve structural organization", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain neuron fate commitment", "Forebrain radial glial cell differentiation", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "G2 mi transition of meiotic cell cycle", "Galactolipid biosynthetic process", "Galactolipid metabolic process", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastric acid secretion", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glomerulus morphogenesis", "Glomerulus vasculature morphogenesis", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione catabolic process", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Heat generation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 demethylation trimethyl h3 k4 specific", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus cell migration", "Hypothalamus development", "Hypothalamus gonadotrophin releasing hormone neuron differentiation", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid catabolic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate biosynthetic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate biosynthetic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lacrimal gland development", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learned vocalization behavior or vocal learning", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteolysis", "Lymph vessel development", "Lymph vessel morphogenesis", "Lymphangiogenesis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage activation involved in immune response", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of animal organ identity", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Marginal zone b cell differentiation", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane fusion involved in viral entry into host cell", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motor behavior", "Motor learning", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Motor neuron migration", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multinuclear osteoclast differentiation", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myoblast proliferation", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Nail development", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immune response to tumor cell", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic process involved in development", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of atpase coupled calcium transmembrane transporter activity", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axon extension involved in axon guidance", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of catecholamine secretion", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell migration involved in sprouting angiogenesis", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell proliferation involved in kidney development", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular extravasation", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of dopamine secretion", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of g0 to g1 transition", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of granulocyte differentiation", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of hepatocyte apoptotic process", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrogen peroxide metabolic process", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 beta production", "Negative regulation of interleukin 1 production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage derived foam cell differentiation", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell activation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil activation", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of nlrp3 inflammasome complex assembly", "Negative regulation of non canonical wnt signaling pathway", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of pathway restricted smad protein phosphorylation", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of ribosome biogenesis", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of smad protein signal transduction", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell differentiation", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of torc1 signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Netrin activated signaling pathway", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest cell migration involved in autonomic nervous system development", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron neuron synaptic transmission", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nitrogen utilization", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Observational learning", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Olfactory nerve development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast development", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Osteoclast fusion", "Otic vesicle development", "Otic vesicle formation", "Otic vesicle morphogenesis", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parasympathetic nervous system development", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification process", "Penetration of zona pellucida", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine monomethylation", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericardium development", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine acyl chain remodeling", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet dense granule organization", "Platelet derived growth factor receptor alpha signaling pathway", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adenylate cyclase activity", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic process involved in development", "Positive regulation of apoptotic process involved in morphogenesis", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagosome maturation", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axon extension involved in axon guidance", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle cell differentiation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cd8 positive alpha beta t cell differentiation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular ph reduction", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental pigmentation", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell chemotaxis by vegf activated vascular endothelial growth factor receptor signaling pathway", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of heat generation", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 23 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte adhesion to vascular endothelial cell", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term synaptic depression", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of meiotic cell cycle", "Positive regulation of meiotic cell cycle phase transition", "Positive regulation of meiotic nuclear division", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myoblast proliferation", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immune response to tumor cell", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of osteoclast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of peroxisome proliferator activated receptor signaling pathway", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein localization to synapse", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of store operated calcium channel activity", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of uterine smooth muscle contraction", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor receptor signaling pathway", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vasoconstriction", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein deglutamylation", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked deubiquitination", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c activating g protein coupled receptor signaling pathway", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to site of double strand break", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein side chain deglutamylation", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Recognition of apoptotic cell", "Recombinational repair", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic process involved in development", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte differentiation", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of blood vessel remodeling", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone mineralization involved in bone maturation", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching involved in ureteric bud morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell differentiation", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd40 signaling pathway", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cd8 positive alpha beta t cell differentiation", "Regulation of cdc42 protein signal transduction", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell proliferation involved in kidney development", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular ph reduction", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte development", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of heat generation", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte apoptotic process", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte adhesion to vascular endothelial cell", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphangiogenesis", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myoblast proliferation", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immune response to tumor cell", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil activation", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil degranulation", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non canonical wnt signaling pathway", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast development", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phosphatidylinositol dephosphorylation", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor activity", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of cardiac muscle", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sensory perception", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle cell proliferation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of somatic stem cell population maintenance", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle cycle", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of ventricular cardiac muscle cell membrane depolarization", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of voltage gated sodium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Regulatory t cell differentiation", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system process involved in regulation of systemic arterial blood pressure", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cycloheximide", "Response to cytokine", "Response to dexamethasone", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 17", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to pheromone", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to staurosporine", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to water deprivation", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell programmed cell death", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Semicircular canal development", "Semicircular canal morphogenesis", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of taste", "Sensory perception of temperature stimulus", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thioester biosynthetic process", "Thioester metabolic process", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Trigeminal ganglion development", "Trigeminal nerve development", "Trigeminal nerve morphogenesis", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Tripartite regional subdivision", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urea cycle", "Urea metabolic process", "Ureter development", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Vestibulocochlear nerve development", "Vestibulocochlear nerve morphogenesis", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT4", "AGPAT5", "AGPS", "AGTPBP1", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APIP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAP1", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATM", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C19orf70", "C1QBP", "C21orf59", "C2CD2L", "C2CD5", "C2orf49", "C3orf58", "C5orf51", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC115", "CCDC124", "CCDC22", "CCDC47", "CCDC6", "CCDC93", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPF", "CENPU", "CENPV", "CEP250", "CEP290", "CEP44", "CEP55", "CEP97", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHM", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHTF18", "CHTF8", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNP", "CNPY2", "COA3", "COASY", "COG5", "COG7", "COG8", "COIL", "COLGALT1", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF15", "DCAF16", "DCAF7", "DCAKD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX31", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND5B", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2A", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DR1", "DRG1", "DRG2", "DSC2", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFL1", "EFR3A", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETHE1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EYA4", "EZR", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM105A", "FAM120B", "FAM126A", "FAM129B", "FAM162A", "FAM208A", "FAM20B", "FAM213A", "FAM49B", "FAM50A", "FAM83D", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXL18", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FSD1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYCO1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHITM", "GID8", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNB1L", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK1", "HP1BP3", "HPF1", "HPRT1", "HPS5", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90AB4P", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS14", "INTS3", "INTS4", "INTS6", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRS4", "ISCA2", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KATNB1", "KCTD10", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA1211", "KIAA1468", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNSTRN", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC14", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRFIP1", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LZTFL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP2", "METTL13", "METTL25", "METTL7B", "MFAP1", "MFGE8", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMACHC", "MMS19", "MOCS1", "MOCS2", "MOCS3", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS27", "MRPS30", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFR", "MTIF2", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NET1", "NEU1", "NF1", "NFATC2IP", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PARS2", "PATL1", "PAWR", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXP", "PEBP1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF6", "PHGDH", "PHIP", "PHLDB2", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "POMP", "PON2", "POP1", "POR", "POU2F1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF18", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRUNE1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB36", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RABEP1", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAF1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RASAL2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBBP9", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM47", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RGS10", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIOX2", "RIPK1", "RMC1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL1", "SCYL2", "SDAD1", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFMBT1", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGK3", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIN3A", "SIPA1", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SMYD4", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX14", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRA1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TAPBP", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFB2M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM7SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM199", "TMEM201", "TMEM214", "TMEM33", "TMEM43", "TMEM87A", "TMEM97", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TNRC6A", "TOE1", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TONSL", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC28", "TTC37", "TTC4", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL4A", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR2", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP32", "USP34", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMP1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "WAPL", "WARS", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR35", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR62", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WLS", "WNK1", "WRAP53", "WRAP73", "WTAP", "WWP2", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO6", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["AASDHPPT", "ABCB1", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABHD10", "ABI1", "ACAD11", "ACAP2", "ACAT2", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTN4", "ADAR", "ADNP", "ADPGK", "AFG3L2", "AGPAT5", "AHCYL1", "AIFM1", "AKAP8L", "AKAP9", "ALDH18A1", "ALDH2", "ALDH3A2", "ALG1", "ALG11", "AMPD2", "ANAPC1", "ANAPC5", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANO6", "ANXA1", "ANXA2", "ANXA6", "AP3B1", "AP3M1", "AP3S1", "APEX1", "APOL2", "APOO", "APOOL", "APP", "ARG2", "ARHGEF2", "ARL6IP1", "ASAH1", "ASNA1", "ATAD3A", "ATAD3B", "ATAD5", "ATG7", "ATG9A", "ATL2", "ATM", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATR", "AURKA", "AURKB", "B3GALT6", "B4GALT3", "B4GAT1", "BAG4", "BAG6", "BAIAP2", "BAX", "BAZ1B", "BCAP31", "BCAS3", "BCKDHB", "BCKDK", "BCL2L13", "BECN1", "BICD2", "BLOC1S1", "BSG", "BUB1", "BUB1B", "BUD23", "C12orf73", "C19orf70", "C1QBP", "C3orf58", "CAMK1", "CANX", "CASK", "CASP3", "CCDC47", "CCNB1", "CCNB2", "CD109", "CDC16", "CDC23", "CDC37", "CDC40", "CDC42", "CDK11B", "CDK2", "CDK5RAP3", "CEP290", "CERS1", "CERS2", "CETN2", "CHCHD3", "CHD7", "CHEK1", "CIRBP", "CISD1", "CLCC1", "CLCN7", "CLN5", "CLPTM1", "CLPTM1L", "CLPX", "CLUH", "CNNM3", "CNNM4", "COA3", "COMT", "COX15", "COX2", "COX4I1", "COX6B1", "COX7A2", "CPOX", "CPT1A", "CPT2", "CPVL", "CRK", "CRTAP", "CSNK1A1", "CSNK2B", "CTNNB1", "CTR9", "CTSA", "CUL5", "CUTA", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAGLB", "DAZAP1", "DCAKD", "DCP1A", "DCTD", "DCTPP1", "DCUN1D4", "DCUN1D5", "DDRGK1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX56", "DERL1", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHRS7B", "DHX36", "DHX37", "DHX8", "DHX9", "DIABLO", "DICER1", "DIMT1", "DKC1", "DNAJB11", "DNAJC1", "DNAJC11", "DNAJC13", "DNM2", "DNMT1", "DOCK7", "DOHH", "DOLPP1", "DPM1", "DSE", "DSP", "DYNLL1", "EARS2", "ECE1", "ECSIT", "EHD4", "EIF2B2", "EMC4", "EMC7", "EMD", "EMG1", "ENDOG", "ENY2", "EPB41L3", "EPDR1", "EPHX1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERGIC3", "ERLIN1", "ESPL1", "ETFDH", "EXO1", "EXOC2", "EXOC7", "FADS2", "FAM129B", "FAM162A", "FAM208A", "FAM49B", "FAM8A1", "FANCA", "FANCD2", "FAR1", "FAR2", "FASN", "FBL", "FCGRT", "FDFT1", "FECH", "FGFR1OP", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "FKRP", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXC1", "FOXRED1", "FTSJ3", "FUBP1", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "GAA", "GALNT1", "GALNT4", "GAR1", "GBA", "GBE1", "GBF1", "GDAP1", "GGCX", "GGH", "GLA", "GLB1", "GLDC", "GLG1", "GLUD1", "GM2A", "GNA13", "GNAI2", "GNL3L", "GNPAT", "GNS", "GOLGA5", "GOLPH3", "GOSR1", "GPAA1", "GPD2", "GPR107", "GPR108", "GPR180", "GRB2", "GSK3A", "GSTA4", "GUSB", "H2AFY", "HACD3", "HADH", "HADHA", "HAT1", "HCCS", "HDAC1", "HDAC6", "HDGFL2", "HEATR1", "HEBP2", "HEXA", "HGS", "HIP1", "HIP1R", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMCES", "HMGB1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPR", "HNRNPU", "HS2ST1", "HSD17B12", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HTT", "HUWE1", "ICMT", "IDH1", "IDH2", "IFT52", "IGBP1", "IKBIP", "ILVBL", "IMMT", "INA", "IPO7", "IPO8", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "JAGN1", "KDELR1", "KDELR3", "KDM1B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIDINS220", "KIF5B", "KMT2A", "KPNA1", "KPNA6", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LARS", "LBR", "LCLAT1", "LETM1", "LGALS3", "LGALS3BP", "LIG3", "LIN9", "LMAN1", "LMAN2", "LMF2", "LMNA", "LNPEP", "LONP1", "LPCAT1", "LRP1", "LRRC8A", "LUC7L", "MAGED1", "MAGT1", "MAN1A2", "MAN2A1", "MASTL", "MATR3", "MAU2", "MAVS", "MBOAT7", "MCL1", "MCM2", "MCM3AP", "MCU", "MFGE8", "MFN1", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MICU2", "MIEF1", "MIF", "MIGA1", "MINPP1", "MIPEP", "MMAB", "MOSPD2", "MOV10", "MPC2", "MPP2", "MPST", "MPV17L2", "MRPL2", "MRPL58", "MRPS18A", "MRPS30", "MSH6", "MSMO1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTHFR", "MTO1", "MTOR", "MTR", "MTX1", "MUT", "MYCBP2", "MYDGF", "MYO1B", "MYO1D", "MYO1E", "NAA15", "NAA40", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NASP", "NAT10", "NBAS", "NCAPD3", "NCAPH", "NCKAP1", "NCOA5", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NECTIN2", "NEDD4", "NEDD4L", "NEFM", "NEU1", "NISCH", "NLN", "NMD3", "NNT", "NOL8", "NOM1", "NOP14", "NOP2", "NOP9", "NPC1", "NPC2", "NPEPPS", "NRDC", "NRP1", "NSD2", "NSMCE2", "NSUN2", "NSUN5", "NT5C2", "NT5C3B", "NUCB2", "NUCKS1", "NUDT16", "NUDT16L1", "NUDT19", "NUDT21", "NUF2", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP214", "NUP37", "NUP54", "NUP88", "NUP93", "NXF1", "NXN", "OCIAD1", "OCLN", "OGDH", "OLA1", "OPA1", "OS9", "OSBP", "OSBPL8", "OSBPL9", "OXA1L", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "PABPC1", "PABPN1", "PAK2", "PARP1", "PARP2", "PBRM1", "PCID2", "PCM1", "PCYOX1", "PDCD5", "PDHB", "PDK1", "PDK3", "PDSS1", "PDSS2", "PEX14", "PEX19", "PGRMC1", "PGRMC2", "PHB2", "PHF2", "PI4K2A", "PIBF1", "PIGU", "PIP4K2C", "PISD", "PITRM1", "PKP2", "PLA2G15", "PLBD2", "PLCG2", "PLD3", "PLD6", "PLEKHA7", "PLK1", "PLOD3", "PMPCA", "PNPLA8", "POLDIP2", "POLDIP3", "POLE", "POLR1E", "POLRMT", "POMGNT2", "PON2", "POR", "PPME1", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPT1", "PRCP", "PRDX4", "PREB", "PREPL", "PRKAA2", "PRKCB", "PRKDC", "PRKRA", "PRMT5", "PRMT9", "PRPF31", "PRPF40A", "PRPF8", "PSAP", "PSMB2", "PSMB6", "PSMD10", "PSME2", "PSMF1", "PTBP2", "PTDSS1", "PTGES2", "PTPN1", "PTPRF", "PUF60", "PUS7", "PXMP2", "RAB11B", "RAB24", "RAB7A", "RABL3", "RAC1", "RAD21", "RAD50", "RAF1", "RALY", "RANBP2", "RANGRF", "RAPGEF2", "RBM10", "RBM14", "RBM15", "RBM3", "RBM4", "RBM47", "RBM5", "RBM6", "RBM7", "RBMX", "REPS1", "RER1", "RETSAT", "RFLNB", "RHBDD2", "RHOA", "RHOG", "RINT1", "RIOK1", "RIOK2", "RIPK1", "RMDN1", "RMND1", "RNASEH2B", "RNASET2", "RNF2", "ROCK1", "RPL10", "RPN2", "RPS12", "RPS15", "RPS6", "RPS6KA1", "RPS6KA3", "RPUSD3", "RRM1", "RRM2", "RTN3", "RTN4", "S100A13", "SAMM50", "SARNP", "SC5D", "SCAMP2", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCPEP1", "SDCBP", "SDF4", "SDHB", "SEC11A", "SEC16A", "SEC24B", "SEC63", "SEL1L", "SENP3", "SETD2", "SF3B1", "SF3B4", "SF3B5", "SFMBT1", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SHCBP1", "SHMT1", "SIGMAR1", "SIN3A", "SIRT2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC2A1", "SLC35A4", "SLC35B2", "SLC39A14", "SLC4A7", "SLC7A1", "SLIT2", "SLMAP", "SLU7", "SMARCC1", "SMARCD1", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAPIN", "SNRPD2", "SNU13", "SNX27", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SORT1", "SPART", "SPNS1", "SPTLC1", "SPTLC2", "SQLE", "SRPK2", "SRPRB", "SSBP1", "SSNA1", "SSR1", "STAMBP", "STARD3", "STAT1", "STOML2", "STT3A", "STT3B", "STX12", "STX18", "STX3", "STX5", "STX8", "STXBP3", "SULT2A1", "SUN1", "SUN2", "SURF4", "SUZ12", "SYNCRIP", "SYNJ2BP", "TAF15", "TAF6L", "TAMM41", "TAOK1", "TAP1", "TAP2", "TARS2", "TBL2", "TCERG1", "TDRKH", "TECR", "TEFM", "TERF2", "TEX264", "TFB1M", "TFB2M", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC5", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM8B", "TIMM9", "TM7SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED7", "TMED9", "TMEM126A", "TMEM199", "TMEM201", "TMEM33", "TMEM87A", "TMEM97", "TMLHE", "TMTC3", "TMX2", "TNPO1", "TOMM22", "TOMM5", "TOMM70", "TOP2A", "TOP2B", "TOPBP1", "TOR1AIP2", "TP53", "TPBG", "TPM1", "TPP1", "TPR", "TRA2A", "TRA2B", "TRAM1", "TRAPPC5", "TRIP13", "TRMT1L", "TRMT61A", "TRMU", "TRRAP", "TSN", "TSPAN6", "TSPO", "TST", "TTC19", "TTC26", "TTK", "TTYH3", "TUBB", "TUBB2B", "TUBB4B", "TWNK", "TXNDC12", "TYSND1", "U2AF1", "U2AF2", "UBAP2L", "UBR2", "UFL1", "UNC119", "UNC119B", "UQCR10", "UQCRC1", "UQCRQ", "USP15", "USP19", "USP4", "USP47", "USP7", "UTP15", "UXT", "VAMP7", "VANGL1", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VMP1", "VPS13A", "VPS4A", "WASHC5", "WBP2", "WDR35", "WDR43", "WDR48", "WDR6", "WDR75", "WFS1", "WIPI2", "WLS", "WRAP73", "WWP2", "XAB2", "XPO4", "XPO5", "XRN2", "YBX1", "YTHDC1", "YTHDC2", "YTHDF2", "ZADH2", "ZC3HAV1", "ZCCHC3", "ZMPSTE24", "ZNF207", "ZNF326", "ZNF622"]} \ No newline at end of file diff --git a/msigdb_gocc/advanced/idx2term.json b/msigdb_gocc/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a583fa2daed871e1a17be5afce24c918c03067d8 --- /dev/null +++ b/msigdb_gocc/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Nuclear outer membrane endoplasmic reticulum membrane network", "1": "Endoplasmic reticulum", "2": "Organelle subcompartment", "3": "Organelle inner membrane", "4": "Mitochondrial envelope", "5": "Envelope", "6": "Intrinsic component of organelle membrane", "7": "Vacuole", "8": "Lysosomal lumen", "9": "Intrinsic component of plasma membrane"} \ No newline at end of file diff --git a/msigdb_gocc/advanced/plot_0.png b/msigdb_gocc/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8a2910bf5ba97ca111d7fae6e6549900ed114b94 --- /dev/null +++ b/msigdb_gocc/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d88b1e56efee9a442912a3628d2f7c80ae9de9d5b34037d4e550ca3c65cf98d9 +size 236449 diff --git a/msigdb_gocc/advanced/plot_1.png b/msigdb_gocc/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..86139253ab044e7df190e59e51865cdaaf9d80e4 --- /dev/null +++ b/msigdb_gocc/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:442a6d5fbb41d59a7336aeb166b2d52b56236fd494deb4d20c48899feeefbbcb +size 232365 diff --git a/msigdb_gocc/advanced/plot_2.png b/msigdb_gocc/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..296c11eb20cc97080e5c6f536e028136bb02574a --- /dev/null +++ b/msigdb_gocc/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8b43c9926be241e3522e840b85df7e25ba2122e004ab583536f5cf83822a89b9 +size 234545 diff --git a/msigdb_gocc/advanced/plot_3.png b/msigdb_gocc/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..3eb2ce6140ebd8e912249a1e5e5f894bf927d454 --- /dev/null +++ b/msigdb_gocc/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c2879d682647ea3e80631ce408cd88c737de3d8fb5850b307875bedc5023a8bc +size 223810 diff --git a/msigdb_gocc/advanced/plot_4.png b/msigdb_gocc/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..3ba8381c60eef2ec9ab102ba9e831bc42fd4a942 --- /dev/null +++ b/msigdb_gocc/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:61fd1ea7d05c401eb6c53379d7af429066edbddf7c6d0afa537f68a0f4a11521 +size 231918 diff --git a/msigdb_gocc/advanced/plot_5.png b/msigdb_gocc/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..2220ae0bd58a8d60f02c6527bce3dbd62b00099b --- /dev/null +++ b/msigdb_gocc/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d9492047d8ea416d376f7d4111009ce908dc6f6511829a44d7396bf9abf0b57c +size 230782 diff --git a/msigdb_gocc/advanced/plot_6.png b/msigdb_gocc/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..c6a5544f99c670004e90de1a7c6a70a261aa857c --- /dev/null +++ b/msigdb_gocc/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:63b4fea85d5389a366c074f89b9f3fe2f7517e83a1b0412478beda11e68c9cb1 +size 218403 diff --git a/msigdb_gocc/advanced/plot_7.png b/msigdb_gocc/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..7923d8b3146a3ee9da4b25a707f173b582c244a3 --- /dev/null +++ b/msigdb_gocc/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c5dd38966d7c5453fb5b340191f8e343ba97d3cf2190e8aa75c6d1835cdf7138 +size 218273 diff --git a/msigdb_gocc/advanced/plot_8.png b/msigdb_gocc/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..26a2ee3285638fd91af65fcad73aabffea91fa9c --- /dev/null +++ b/msigdb_gocc/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:091310a28fcb56e1501d95d453bc15dd7c5b25d774037f5cfd1e17efee594a5b +size 197695 diff --git a/msigdb_gocc/advanced/plot_9.png b/msigdb_gocc/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..12aa7d36a608af8f9cc3ef8389c10defc640633b --- /dev/null +++ b/msigdb_gocc/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9a293844783b607323af69376f412e175a5f4f180a8245fbbc1b51be70041e57 +size 214459 diff --git a/msigdb_gocc/basic/idx2term.json b/msigdb_gocc/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..0e71e26d5e45756002339c7c486fd5934aaf4596 --- /dev/null +++ b/msigdb_gocc/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Nuclear outer membrane endoplasmic reticulum membrane network", "1": "Endoplasmic reticulum", "2": "Organelle subcompartment", "3": "Organelle inner membrane", "4": "Mitochondrial envelope", "5": "Envelope", "6": "Intrinsic component of organelle membrane", "7": "Vacuole", "8": "Lysosomal lumen", "9": "Intrinsic component of plasma membrane", "10": "Intrinsic component of endoplasmic reticulum membrane", "11": "Vacuolar lumen", "12": "Mitochondrial protein containing complex", "13": "Inner mitochondrial membrane protein complex", "14": "Outer membrane", "15": "Mitochondrion", "16": "Golgi apparatus", "17": "Membrane protein complex", "18": "Vacuolar membrane", "19": "Secretory granule membrane", "20": "Respirasome", "21": "Golgi membrane", "22": "Endoplasmic reticulum lumen", "23": "Intrinsic component of mitochondrial membrane", "24": "Endocytic vesicle membrane", "25": "Azurophil granule", "26": "Intrinsic component of mitochondrial inner membrane", "27": "Nuclear envelope", "28": "Endocytic vesicle", "29": "Nuclear inner membrane", "30": "Microbody", "31": "Phagocytic vesicle", "32": "Endoplasmic reticulum golgi intermediate compartment membrane", "33": "Microbody membrane", "34": "Endoplasmic reticulum protein containing complex", "35": "Endoplasmic reticulum golgi intermediate compartment", "36": "Phagocytic vesicle membrane", "37": "Vesicle membrane", "38": "Nuclear membrane", "39": "Azurophil granule membrane", "40": "Azurophil granule lumen", "41": "Outer mitochondrial membrane protein complex", "42": "Oxidoreductase complex", "43": "Basolateral plasma membrane", "44": "Organelle membrane contact site", "45": "Cytochrome complex", "46": "Transporter complex", "47": "Late endosome", "48": "Microbody lumen", "49": "Organelle envelope lumen"} \ No newline at end of file diff --git a/msigdb_gocc/basic/plot_0.png b/msigdb_gocc/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..23ac4367b8042fd2ec1e6012bfa23be311eb15ea --- /dev/null +++ b/msigdb_gocc/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bba8d8f5de8205c5cb4a9c154ea300c4d0e8a41352f253ee2f06ab53c88d2a9b +size 145050 diff --git a/msigdb_gocc/basic/plot_1.png b/msigdb_gocc/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..c274a07bfbdd4dbe23abb485cacfa0f4678209e3 --- /dev/null +++ b/msigdb_gocc/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4f460f4b09062cc59c39e615a953f7736ae2ca3352c4eae33616d9a3dd79e995 +size 143985 diff --git a/msigdb_gocc/basic/plot_10.png b/msigdb_gocc/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..909bf16b92fcc8510d11795aed4cec581547be91 --- /dev/null +++ b/msigdb_gocc/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e5cafa460c67b8e874862a436ea43299d0f5b8f7e4e22cc865472cd5a3d0c3e4 +size 149442 diff --git a/msigdb_gocc/basic/plot_11.png b/msigdb_gocc/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..322713c1e44a8125fbfec8384158fb66c986ff27 --- /dev/null +++ b/msigdb_gocc/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1fba74d7d6e2f62343a9cc6e58b6c14d2db8f0baf32d23b314696d921f5ff96c +size 140937 diff --git a/msigdb_gocc/basic/plot_12.png b/msigdb_gocc/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..ab1b8b29140cbca16342ccb09d0c83aca3ef5282 --- /dev/null +++ b/msigdb_gocc/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c91507b6e8acddeffb09114a5138acda8183dc209c971eafd090115155a21741 +size 152220 diff --git a/msigdb_gocc/basic/plot_13.png b/msigdb_gocc/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..807ba3e27b3ae1fbe486ff842479cad280ca07db --- /dev/null +++ b/msigdb_gocc/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:23191a79e51d05f93861fd89d056db5957d6f346221d2c8769ec5a316c2cba03 +size 146283 diff --git a/msigdb_gocc/basic/plot_14.png b/msigdb_gocc/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..fa04af059c4444658a5f89f85bfb4e96f88db1ca --- /dev/null +++ b/msigdb_gocc/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:049c13cd90c366a70a8cea4df59d52b8e72249bd3cd8e27f4da5e376212e649e +size 137294 diff --git a/msigdb_gocc/basic/plot_15.png b/msigdb_gocc/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..75045e30023b5ec21f41b04110ed2e99f9f61196 --- /dev/null +++ b/msigdb_gocc/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a199725bbbd058da1198f653d1b612a422d32536c7c16ed6685aff13c390647a +size 138376 diff --git a/msigdb_gocc/basic/plot_16.png b/msigdb_gocc/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..1eb6f97e5488fe1806e774a6d2a36265cec392b3 --- /dev/null +++ b/msigdb_gocc/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:401967d81510cf5d3763008750427ed411621fb84a474248fece42becae565b2 +size 145285 diff --git a/msigdb_gocc/basic/plot_17.png b/msigdb_gocc/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..b307d0f62eab9034f6790815e64023902cdb1265 --- /dev/null +++ b/msigdb_gocc/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:510b149d0e59e177dd796c5d99237ec22e44caf5f0ce39ea03287c5691f7c08c +size 145698 diff --git a/msigdb_gocc/basic/plot_18.png b/msigdb_gocc/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..1a4a05dd1d5e51f70219ddd6244378d7b9b37f5a --- /dev/null +++ b/msigdb_gocc/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7316ec08fa27d4af4d04cc96935adcbe8e216a3e3ebdc5234aea66cf5ee2be56 +size 144496 diff --git a/msigdb_gocc/basic/plot_19.png b/msigdb_gocc/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..d943a1a2e9678fe3c0c06bb879a3b9901be91235 --- /dev/null +++ b/msigdb_gocc/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6f3db1be67b2e1351c0056d3da7f5634a34145b9ea9c8d24d013d0030b8e2bd2 +size 153799 diff --git a/msigdb_gocc/basic/plot_2.png b/msigdb_gocc/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..5477d059354ad0279055da186c552d790d6588e5 --- /dev/null +++ b/msigdb_gocc/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:03c5f635a9d1277650501d41aaa28a210bfc94ad2e19de17e1e0a4ead548205f +size 148276 diff --git a/msigdb_gocc/basic/plot_20.png b/msigdb_gocc/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..18d9cd8547dd515bdefc7fa86ac490afb5b118b3 --- /dev/null +++ b/msigdb_gocc/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f090f4f96584a940bc4834e238070893c4906bda8bb6b363b2efe207b6d61720 +size 140195 diff --git a/msigdb_gocc/basic/plot_21.png b/msigdb_gocc/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..44d9b9e456f78253983b8e31783c84afb8fc9dc1 --- /dev/null +++ b/msigdb_gocc/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bed09a91a5383797298aba152c1c37c0f7cb1fb1f6669d470c670171dc41425c +size 145962 diff --git a/msigdb_gocc/basic/plot_22.png b/msigdb_gocc/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..9a295bbcd0fe7b830dfda0502a6838fd5f2f9207 --- /dev/null +++ b/msigdb_gocc/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8878304102e17a884e8a1fe597f629ea0f0d7d29fc96c785394afccfcbdf0d3a +size 150259 diff --git a/msigdb_gocc/basic/plot_23.png b/msigdb_gocc/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..da1ec021827b0230cb5f3461b2a6e04e3c07bcc1 --- /dev/null +++ b/msigdb_gocc/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f67d6987af130d479377e54e6ce389d0dd4f310e0d032887c41dc546cefc269d +size 147104 diff --git a/msigdb_gocc/basic/plot_24.png b/msigdb_gocc/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..9e1f987b9e96b3674bf632a6c436c72f1a2c20bf --- /dev/null +++ b/msigdb_gocc/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:facb2b6d1e900f54872a51b00318802fb793ecea53becdc9c3fe05db50c2a798 +size 145008 diff --git a/msigdb_gocc/basic/plot_25.png b/msigdb_gocc/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..47894d5015c122a6313d997d591859af26bcd556 --- /dev/null +++ b/msigdb_gocc/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ccd1517d32eb08d601d7cd6dd547b1f80e35d10f9a9118a1d0012126c1f9ccf8 +size 147457 diff --git a/msigdb_gocc/basic/plot_26.png b/msigdb_gocc/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..17567acee703fb0c082e2081e73b5c3e9b30fbbc --- /dev/null +++ b/msigdb_gocc/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3da273b330f20ea39131dc3150d61643dc729837e5e9d2d559e6fee3e0f63c7d +size 148392 diff --git a/msigdb_gocc/basic/plot_27.png b/msigdb_gocc/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..c91db1be5e6e651e1308a5d28162a1dbf42a0189 --- /dev/null +++ b/msigdb_gocc/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:70982000fd5d23fe050b673846e7bd8b0df916ff61a1f6182a345357408c75bb +size 143216 diff --git a/msigdb_gocc/basic/plot_28.png b/msigdb_gocc/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..cc126b271c34679f138376f42778cfd11cf84f7b --- /dev/null +++ b/msigdb_gocc/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cbff431d9b859c1ca7714698db53e36d8cc7421b97bcbcc6a601fd41fc31329d +size 147083 diff --git a/msigdb_gocc/basic/plot_29.png b/msigdb_gocc/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..0add5ec48e51779c5198582a4740ef19ced4c8c9 --- /dev/null +++ b/msigdb_gocc/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:289fa41d59daf8596215544bdd7ab147330f97b7e75e7cb77bbf4fe6e7f5acf6 +size 141865 diff --git a/msigdb_gocc/basic/plot_3.png b/msigdb_gocc/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..b8c6007bb3a21b1a617224711956498d502b07a2 --- /dev/null +++ b/msigdb_gocc/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fa4c880a4488b5102f8be510dd497eba4568225b9080f740f1acb76edc09412d +size 143317 diff --git a/msigdb_gocc/basic/plot_30.png b/msigdb_gocc/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..4d92fd38e08d5cf66e2809b3476cd5e1f37140fc --- /dev/null +++ b/msigdb_gocc/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:433673e09589741279279d970bc56ebd2b4232599ad2a5cd7f42042823b63a18 +size 141144 diff --git a/msigdb_gocc/basic/plot_31.png b/msigdb_gocc/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..a3cd9c9c9f3525860b7570b02daed9fbf9e78f76 --- /dev/null +++ b/msigdb_gocc/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ed701bb4ff3ab0b62f13b7b1047be738c00a70e6b84387fb2b982b0b17d0d18d +size 147565 diff --git a/msigdb_gocc/basic/plot_32.png b/msigdb_gocc/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..f362763a2de82ca838c138fafa3e638f1dbd58d1 --- /dev/null +++ b/msigdb_gocc/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:27b0fc5d590cfd52676bfa2c34fd90f9538154ad82dc4c82793c90b8c301df2f +size 147212 diff --git a/msigdb_gocc/basic/plot_33.png b/msigdb_gocc/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..769318fdd587bd396ce5e84ecb523ac0ed6fb53d --- /dev/null +++ b/msigdb_gocc/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d4b7dbe45e4a6fa98bebd6bb8660091d85938af8b48c6daae47556c4507414de +size 140926 diff --git a/msigdb_gocc/basic/plot_34.png b/msigdb_gocc/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..ed9893ab29db5fb964caf9f9f933309c420ceba3 --- /dev/null +++ b/msigdb_gocc/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:00b1644dee04fc7f86b8797d3438fbb52bf8129b4a59172856a6d018f878f8c9 +size 152337 diff --git a/msigdb_gocc/basic/plot_35.png b/msigdb_gocc/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..4cf4bfecf9b6a2d44e73366eebc6e926bed398ef --- /dev/null +++ b/msigdb_gocc/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6666e9fc2e7dc04b4b507fbc0fae5df97e44afdc91cf813834fba65f7dca7bc2 +size 152077 diff --git a/msigdb_gocc/basic/plot_36.png b/msigdb_gocc/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..3caae4b7d0f74f420ea7748838b5bb5bddd8c5c7 --- /dev/null +++ b/msigdb_gocc/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:65f541c411c6d7d6cb2053242c5f04e0aa37cae3a64b68f73483e6f7f19ffca6 +size 142987 diff --git a/msigdb_gocc/basic/plot_37.png b/msigdb_gocc/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..15d343cb434c18812568d339264c0171435e1c9f --- /dev/null +++ b/msigdb_gocc/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8a3981cd040b4e7f8520eacd1305a8431074f9a510d8886ca75e7fd6499d3fac +size 140566 diff --git a/msigdb_gocc/basic/plot_38.png b/msigdb_gocc/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..9229eba49f4c5224982102cfa9695ccff98d1b8c --- /dev/null +++ b/msigdb_gocc/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6d253ee6d62771257507d867efc0a5154fe5efa71ca997f8d0d780e2562d42f3 +size 144962 diff --git a/msigdb_gocc/basic/plot_39.png b/msigdb_gocc/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..29c4c27e3e76946fb485907cf5f4d760da535ab8 --- /dev/null +++ b/msigdb_gocc/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9e5eab93441d12c33e65fbd007e96d1748a53a54e242e1e0a53d8d9ffdcee77b +size 139290 diff --git a/msigdb_gocc/basic/plot_4.png b/msigdb_gocc/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..543cccccff872ab057dc3de54b2b68f9547dddfd --- /dev/null +++ b/msigdb_gocc/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bd75d365c3e054efb08c321bc8492b4d4439d43471a5810b72831e8de6fd03b5 +size 136828 diff --git a/msigdb_gocc/basic/plot_40.png b/msigdb_gocc/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..773538a1fafc53542e96472bdbbc3a254460d253 --- /dev/null +++ b/msigdb_gocc/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cb8ccc815580c76cce47f7484a46c0e676ca65d7cd8e03ace5eed966ed8e9860 +size 142178 diff --git a/msigdb_gocc/basic/plot_41.png b/msigdb_gocc/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..6a2cffd5bd7f5e994519f47e34488014b43e9193 --- /dev/null +++ b/msigdb_gocc/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f37cf9f6ce0ffe2d30e230bc61338ab9df88a4f5ca6e6932e8192076e34a4d70 +size 143060 diff --git a/msigdb_gocc/basic/plot_42.png b/msigdb_gocc/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..ddc5965056ff6830f19ad7fa98d4a2d17d8c3857 --- /dev/null +++ b/msigdb_gocc/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0b3c5eb8a293f022ea005cba2995d3bf2710bf43ef1add71aec541be3f593197 +size 147944 diff --git a/msigdb_gocc/basic/plot_43.png b/msigdb_gocc/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..6f898f52697b7a63a1496637b140fffe012caa64 --- /dev/null +++ b/msigdb_gocc/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ae7bd06714dc6b970e89dd48d8b4cfff050b33df0551416475a2332e61b0839 +size 146039 diff --git a/msigdb_gocc/basic/plot_44.png b/msigdb_gocc/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..1e003d46ba94e35a558c1dd4484f786e59e07fda --- /dev/null +++ b/msigdb_gocc/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:462f152fde0aa63493b8879997aa8fa70f83b42f61cf6e5b561d421a193d25b7 +size 143906 diff --git a/msigdb_gocc/basic/plot_45.png b/msigdb_gocc/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..9b12ab2a22f0f26c612d3cac46eb82cd206e0056 --- /dev/null +++ b/msigdb_gocc/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b197159ab18f7884421fb29be2ad1d4ce9e6281a4f263ecf3d1df3f2a4a85f40 +size 137233 diff --git a/msigdb_gocc/basic/plot_46.png b/msigdb_gocc/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..021f5e6753ff19edd420281278ce5958fe1e9efb --- /dev/null +++ b/msigdb_gocc/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9a6fe7ad9d0960aea1f14cc6ab0b80e5c68e9d6c1b17871eecbe7053640b2900 +size 134652 diff --git a/msigdb_gocc/basic/plot_47.png b/msigdb_gocc/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..2a48eb213bdc8931279ebe17d5b52425d5322a82 --- /dev/null +++ b/msigdb_gocc/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6ef287923cdbb0d9d21ee754382dc1c9703b18e431863d379eb839e3d33766fc +size 137631 diff --git a/msigdb_gocc/basic/plot_48.png b/msigdb_gocc/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..48287f2a4af4e55bc24dd111f84ca4315069d777 --- /dev/null +++ b/msigdb_gocc/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:58ec0b51fc8d4bcb577db5ee03170f910d25dcb32657bd8a10d4a8a21380f632 +size 130934 diff --git a/msigdb_gocc/basic/plot_49.png b/msigdb_gocc/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..28ca5c2a1be5bab6cdd8869b8f046a3002d0b4de --- /dev/null +++ b/msigdb_gocc/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:58bd5005ac0cd68ba90d8719738a0dff36b5c334516ef617d11851469863b249 +size 139238 diff --git a/msigdb_gocc/basic/plot_5.png b/msigdb_gocc/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..51aab79ac996e14b6bcb8e1fbf60885d770fdcf3 --- /dev/null +++ b/msigdb_gocc/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1b022e1b3c88540523c534200ecaff88c87f74f96b9d896658853fddd410ffef +size 134437 diff --git a/msigdb_gocc/basic/plot_6.png b/msigdb_gocc/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..51c965f9988b0004ae218c117b0114c41f3a20d5 --- /dev/null +++ b/msigdb_gocc/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4e9b98c0523c727566df1b59408bd618b33c891e6223ec8bd4a1a131b5de201c +size 152389 diff --git a/msigdb_gocc/basic/plot_7.png b/msigdb_gocc/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..e68c7b7bd505c2daa23d8756fd67c7d711ce435f --- /dev/null +++ b/msigdb_gocc/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:688d1d735f35a1385ccd7557cb1f0e85391eac1ee775550e1c444d7f8730dfdb +size 142693 diff --git a/msigdb_gocc/basic/plot_8.png b/msigdb_gocc/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..dd6964880ffa6d3ec358907b4671fb7c9f2b2f94 --- /dev/null +++ b/msigdb_gocc/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7c91a50acc78f9e5ee12e437989a1c304ea4e853e226ff75dc6a9a734178b674 +size 128768 diff --git a/msigdb_gocc/basic/plot_9.png b/msigdb_gocc/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..6654bae549810d723977cb677afe80175b7ddcce --- /dev/null +++ b/msigdb_gocc/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:befed94bc52878155693cb98c67456843188458487475b3c0ad6ae22d3e2819e +size 150216 diff --git a/msigdb_gocc/consensus.joblib b/msigdb_gocc/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..569ec641cb1e679228ea314ed0754884eee3c3e9 --- /dev/null +++ b/msigdb_gocc/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6de2c5a13d8b207a1caa1fbd8586a94a5fbb5762f5b1257ecfebb17154ed5a32 +size 200915 diff --git a/msigdb_gocc/df_merge.tsv b/msigdb_gocc/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e2a97f70b4f2229ce245b91b12adc56233067ee9 --- /dev/null +++ b/msigdb_gocc/df_merge.tsv @@ -0,0 +1,58 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Nuclear outer membrane endoplasmic reticulum membrane network 135 314 7.876099416523562 3.3775952564561378e-15 98.3519417475728 305.0218446601942 1.8626549185660248 0.4346737740195964 40.114822105305365 33.029069404441934 2.648813561163414 0.4525721946789457 1.6707975072666813e-14 0.0008804933211056 2.873554437416623e-06 5.056398427514637e-11 3.1718321274689667e-25 +Endoplasmic reticulum 208 488 7.645160472935916 2.0868490451831892e-14 139.71116504854368 475.50728155339806 1.972579372344309 0.4597126503683645 50.29410175615224 47.94654634280014 2.8130551221954065 0.458598772128197 3.7843100924765335e-18 0.0004930627140242 2.7907344712191105e-07 1.6295660506888474e-15 3.2155262461132e-26 +Organelle subcompartment 145 380 7.443225913301841 9.82558432878238e-14 115.97815533980582 370.4077669902912 1.8466078375892352 0.461199583276842 45.24176702976874 43.040100266333 2.697642340677977 0.4541841641473397 1.533078229389017e-13 0.0001688249733212 4.23079818399298e-07 2.2646849854251576e-10 2.1320817733923452e-22 +Organelle inner membrane 112 242 7.08763072855168 1.364274109903568e-12 79.6747572815534 237.5995145631068 1.5941979045672914 0.3906136455525962 32.81710191865129 21.467005610038825 2.570753705211445 0.4244355950981394 7.250230494549851e-17 1.5636292329721694e-11 5.010841720720807e-12 2.0639031216895063e-16 2.4694982465863332e-23 +Mitochondrial envelope 133 320 7.003660090137495 2.493606762786998e-12 98.51456310679612 309.05582524271847 1.3784407074331837 0.4315621435689855 37.853540978552445 29.592036616547553 2.6690149272426917 0.4358105924461398 1.127959163102401e-16 5.193065492896895e-12 1.2659593715461357e-12 2.903780575754586e-16 7.38749699866018e-24 +Envelope 184 493 6.719495697957969 1.8235456792846856e-11 133.55825242718447 476.99271844660194 1.1125762168925015 0.4931727688685032 47.82674034566458 40.415168802184624 2.6300132137901633 0.4489464989697134 2.6783690830146064e-16 4.055172582197531e-12 8.806586293166622e-13 9.252255750993013e-16 2.163385952505968e-25 +Intrinsic component of organelle membrane 74 124 5.973041115580074 2.328711795463094e-09 52.51699029126213 129.34223300970874 2.0732064315361294 0.2796588394070637 24.692225942786415 15.820346456508432 2.8130846896968285 0.39829365000917 8.083339408648809e-08 0.1828350446371612 0.0093418017701205 8.094912830284234e-08 7.26765963322569e-13 +Vacuole 76 216 5.236675304489291 1.634949484246903e-07 55.029126213592235 212.35679611650485 0.7895788564169173 0.4204713883128338 16.092847298969616 21.031446114270427 2.221429361906059 0.4148180554719883 1.3893943755020543e-10 0.0196090971417485 3.172089093350235e-05 1.0461618609137306e-08 1.3342348124434318e-10 +Lysosomal lumen 22 36 4.761029714118096 1.926076842906354e-06 18.075242718446603 34.54368932038835 0.7848519845050315 0.1014568164283454 6.206531846566726 3.2976210873168883 3.038689298289951 0.2012423645269794 1.6315489173232395e-14 0.0003307976495693 1.780319052295975e-08 6.023298639589242e-11 3.643541562748924e-15 +Intrinsic component of plasma membrane 43 78 4.7268138129398345 2.2807020818582657e-06 29.711165048543688 79.49271844660194 0.9914207279546418 0.2992612012372248 13.467745416506318 12.62980929789956 2.1277799030157807 0.3627370007757806 0.1602155901606816 1.0 0.9910122894125446 0.3537664129156864 0.4201983585866494 +Intrinsic component of endoplasmic reticulum membrane 35 54 4.544262311446566 5.512797346174381e-06 21.439320388349515 53.03155339805825 1.5445183869163015 0.2945609219212759 9.936629672422429 6.151523176643304 2.1054078800196185 0.3580268322643601 0.0027602689924991 0.4637995473310806 0.1264484795755822 0.0010142635400163 1.489913276722729e-07 +Vacuolar lumen 29 66 4.53543140492151 5.74858599566852e-06 22.262135922330096 63.33980582524272 0.6562244405592584 0.1887666227175413 6.920437110961116 4.902057024259538 2.8947011026985514 0.298290072492813 6.43645962315233e-13 0.0023718175528313 1.6593868081277729e-07 2.3384015246984838e-09 1.4323684635917258e-14 +Mitochondrial protein containing complex 62 159 4.292116407222438 1.7697811957928522e-05 45.62621359223301 153.59708737864077 0.8032126729603613 0.4024101172023991 21.080430630469312 12.423857071229754 2.191669513941161 0.4117346592056412 2.327259250147247e-09 0.0014576077341971 3.824925934854537e-05 6.123516141476463e-08 8.832870763684016e-12 +Inner mitochondrial membrane protein complex 38 76 4.276496103666513 1.898578782610905e-05 27.97087378640777 75.4635922330097 1.520604987560478 0.2664687480104057 12.043574857699111 6.447783897817093 2.3558486082891616 0.3692317407906862 1.4350034904860657e-07 0.0039003874446117 5.467249505514427e-06 7.258755998641423e-07 7.466021086901901e-10 +Outer membrane 35 93 4.188399356602242 2.8092884452934896e-05 28.936893203883496 87.79611650485437 1.4859238244628277 0.3236686433663402 11.632349354832256 8.24751710010496 1.9336855473946637 0.38878066573106 1.2098460999073184e-05 0.0002393341141964 0.0003912527924292 8.71555849251835e-06 1.7296558384545218e-07 +Mitochondrion 196 641 4.017363481905352 5.885290961660239e-05 150.5606796116505 610.75 0.3893280889581553 0.5444893646695418 55.48150839960472 53.47985851692477 2.1394883185001157 0.4272675793576402 3.012158148900826e-12 2.1236967054505038e-09 6.157310345262981e-11 2.07657708487959e-11 3.932489864933198e-17 +Golgi apparatus 83 326 3.939904225396333 8.151414521440081e-05 79.29126213592232 307.80825242718447 1.0941692666231844 0.5225509759640199 24.90716006851961 39.34912971804267 1.7376904428153446 0.4394682295132952 0.0003205979480696 0.1178145747517522 0.0040410337266267 0.0002051725111415 0.0034352104632842 +Membrane protein complex 95 302 3.914084415553532 9.074788638230302e-05 80.6747572815534 286.40291262135923 0.8072324880333213 0.5482017098759524 27.14508025817277 25.65052264389531 1.8803092756171496 0.4277745875695662 2.115917929336104e-05 0.0047193744973597 0.0055210053020406 0.0001883829229209 4.557909529282619e-08 +Vacuolar membrane 41 123 3.7012646304597454 0.0002145275967702 31.91504854368932 121.20631067961163 0.8693310080509177 0.3422944242486927 10.598363436017626 13.850227259030053 1.9844114292962869 0.3837860427998523 6.969426486906697e-05 0.0240483486663246 0.0175003868213978 7.695940178612998e-05 9.64615962825618e-05 +Secretory granule membrane 22 72 3.6462662420510887 0.0002660782983392 19.699029126213592 69.8495145631068 0.9295860214656708 0.3887665887416008 7.284889203542463 7.49087955205396 1.5950364553562375 0.3903287060113383 0.0048280761878316 0.2224854546727621 0.2618762982391017 0.0334207300358796 0.0005006170446891 +Respirasome 18 45 3.6297553917079575 0.0002836899252656 15.08495145631068 43.37378640776699 1.2524823540042158 0.2922262294299136 6.290312072426717 4.489587979561489 1.7783434517583476 0.3462844006183536 2.278996635203198e-05 0.0650462755169659 0.0001791038943355 3.945295721538818e-05 5.37153859631512e-07 +Golgi membrane 62 136 3.612489721414312 0.0003032711314481 41.28398058252427 131.19174757281553 1.6327747521284677 0.3511039607499193 15.277988344159814 17.44963987873233 1.926180921267262 0.4033858283713009 0.0039652143056461 0.1541980220314314 0.0086685285247613 0.0080664651762468 0.005217927832691 +Endoplasmic reticulum lumen 27 61 3.5575783105808703 0.0003742895366938 18.07766990291262 59.737864077669904 0.9896277047863468 0.3946249358858228 7.513340007333169 6.273245958458151 1.4320597420402308 0.3846324865730224 0.020209039678822 0.5673097728793466 0.2303757485050893 0.0227656027954654 6.931718452984931e-05 +Intrinsic component of mitochondrial membrane 22 43 3.486659448875019 0.0004890937297539 20.225728155339805 46.883495145631066 1.6360090381123027 0.2606204408334349 9.735582728924424 5.567853242112672 2.0682718238883013 0.3438986948818692 1.1199992788285188e-05 0.0571768496395965 0.0074628704993106 2.0650565379923648e-05 4.9483484464243714e-06 +Endocytic vesicle membrane 11 40 3.431156066516371 0.0006010147186485 11.41019417475728 40.75728155339806 0.6528171904926832 0.3529092384633215 4.825015011915381 4.780047567333447 1.5638167276319088 0.3380752375601685 0.0043317882483969 1.0 0.673701145430139 0.006385102481714 0.0087148542276409 +Azurophil granule 26 70 3.378595147720921 0.0007285721548262 20.46359223300971 67.00485436893204 0.4795255752980384 0.3097891700346699 6.177875864944045 5.290582926033595 2.1760997104513735 0.3628132485163926 1.133590630607314e-07 0.1090224971962506 0.0053807722164466 0.000111900171939 5.314475683152223e-09 +Intrinsic component of mitochondrial inner membrane 18 30 3.353365767925465 0.0007983512749325 13.946601941747574 31.446601941747577 1.7062420859184484 0.2149692261988765 6.992163651608136 3.3601842163433866 1.8185871159494191 0.3070405082296492 8.409228956261094e-06 0.0248568883498602 0.0014196759684318 2.499344580454732e-05 3.434860758222829e-06 +Nuclear envelope 51 180 3.105215067624758 0.0019014071632574 37.96116504854369 174.33252427184465 0.0181336977438782 0.7301070934005458 14.47490116343478 13.385385830159189 0.8830829676796945 0.3416784661439265 0.0326338632587797 0.0351537495968446 0.0298766877558385 0.0400236223247248 0.0003003398979554 +Endocytic vesicle 20 86 2.971971484985489 0.0029589416410409 19.521844660194176 83.27669902912622 0.428513908443532 0.5353120905813061 7.647069906220736 7.607555057832984 1.324058617895936 0.3761698531660883 0.0281130221914829 0.6368708263227112 0.3235008162120641 0.0280298561279102 0.000933810737764 +Nuclear inner membrane 12 23 2.963382369677396 0.0030427833405677 7.347087378640777 20.57281553398058 1.3204335588742686 0.2519451141048848 3.6006224195129035 1.9968516080603145 1.2188770932171689 0.2896682474252494 0.0060117255012266 0.0179094063189584 0.0636449972198752 0.0033942963153933 0.0001500964424578 +Microbody 22 60 2.8317932617624195 0.0046287765699999 14.5873786407767 55.157766990291265 0.5308798958236631 0.4622505798174944 6.656600193656261 6.967459933597681 1.141402376279513 0.3502304815174672 0.0404988165441514 0.107450887051756 0.3080186048539914 0.3035960646874314 2.189949342852633e-06 +Phagocytic vesicle 12 42 2.750266227227982 0.0059546863342998 11.54126213592233 41.59708737864078 0.3919256884663005 0.5681630099638236 4.854259100699266 4.0100348958770144 0.9938295058309184 0.3509625084864278 0.0217955460367635 1.0 1.0 0.0355143416714827 0.0010723609662722 +Endoplasmic reticulum golgi intermediate compartment membrane 19 26 2.744203322614048 0.0060657955335183 10.49271844660194 25.839805825242717 1.5441023898993702 0.2324243418613106 5.505729177420246 3.7718384126099376 1.49831312620529 0.2965572765953523 0.0007964121135401 0.0296703391700837 0.0166167011229059 0.0003553897568888 0.0002745691183549 +Microbody membrane 13 26 2.6908178786405004 0.0071277093971455 9.83980582524272 26.8373786407767 1.0322166739723002 0.3740701224912098 5.101262737371427 4.075770333088885 1.3138416014090577 0.3534887732287703 0.0211214409177817 1.0 1.0 0.4074419886033491 0.001584251501391 +Endoplasmic reticulum protein containing complex 28 67 2.6762795385452853 0.0074444524887022 20.067961165048544 61.213592233009706 0.544324442160867 0.4875881372361492 7.672624563199495 5.300944201362535 1.5348103009085623 0.3893079894443684 0.0106655790068841 1.0 1.0 0.0486836099073322 9.367278948654192e-07 +Endoplasmic reticulum golgi intermediate compartment 28 52 2.607297604861522 0.009126000398812 14.888349514563108 49.49271844660194 1.4759277407874345 0.3201471070907981 6.47003250199477 5.053350843348441 1.420924643396655 0.3585240832471577 0.0003975735333625 0.0121763996061447 0.0027125023591343 0.0001337872350923 0.0008853393332325 +Phagocytic vesicle membrane 8 23 2.561419175869233 0.0104245494065806 7.512135922330097 23.83009708737864 0.5348434256443761 0.4468744105904624 3.681144332021715 3.0024693704800938 1.1652764437248655 0.3385441964418395 0.0014849511486613 1.0 1.0 0.0036079185825643 0.0025715943576382 +Specific granule membrane 4 14 2.530676383110699 0.0113842829991961 4.703883495145631 15.434466019417476 0.8701513897757543 0.3699585460258285 2.477017558764293 2.6655071934549124 0.9998631482292508 0.308737972868479 0.047419659933531 0.2145132052110039 0.3837477700803094 0.1171787786101763 0.0882967899938231 +Vesicle membrane 54 273 2.5078958132747657 0.0121452471775906 59.03398058252427 252.66747572815535 0.5350285241159404 0.6113983912197217 17.512237349079548 29.567983380691818 1.3292572988488431 0.402876017449685 0.0050257013202694 0.172469574886243 0.0726841121465539 0.007061852532637 0.0058784069692958 +Nuclear membrane 31 110 2.467835228132589 0.0135932874684816 24.50485436893204 104.91747572815534 -0.1815376114704942 0.591557416265643 11.339743483004588 8.863746684023472 1.043253069233361 0.3390721291700088 0.0640962163618436 0.1067931962753964 0.0798742889342273 0.1196056325886727 0.004968216311582 +Azurophil granule membrane 11 22 2.446884284990626 0.0144097093658395 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 0.0016550408740947 0.2027885470531376 0.0746250944081647 0.0050545837055134 0.0015084049643282 +Azurophil granule lumen 14 44 2.33980372548687 0.0192938764898167 12.118932038834952 41.25728155339806 -0.033426136567579 0.3776020138210581 4.31782609196223 3.0753988435553 1.7699755963815147 0.3570217435028845 5.779772507735339e-05 0.2670314735990955 0.0237837250606552 0.0042402736300421 8.166399063186333e-06 +Outer mitochondrial membrane protein complex 10 16 2.333526167738486 0.0196205465673902 7.157766990291262 15.730582524271844 1.3245491566248977 0.2112996285983387 3.5767402396348245 0.8689557679680192 1.477430451036954 0.2853006280851536 0.002032754568143 0.0937235599037543 0.0161297090986061 0.0120645849010356 0.002252196025852 +Cis golgi network 4 16 2.316869925113403 0.0205108185050484 5.446601941747573 14.91747572815534 1.304763677188147 0.2415633778835601 2.9087352716231463 3.2280604409731746 1.23405443481851 0.2890539664507128 0.0043547723482352 0.0155575631698287 0.006477682080963 0.0146129998399771 0.0393164024746651 +Oxidoreductase complex 24 62 2.2689775994755 0.0232696881194323 16.138349514563107 58.1747572815534 0.4112275970760134 0.4385210691837483 8.292749505639035 5.03902669070441 1.4297411393453454 0.366860872580609 0.0076619924984621 0.0891139899072046 0.017807274362228 0.0123157830103275 0.0001141296100257 +Basolateral plasma membrane 18 41 2.2636624770896527 0.023594882004907 11.907766990291265 41.713592233009706 0.4173504135492652 0.5464661760255546 5.696723454799589 5.533263026209871 1.098008793343998 0.3512755123780914 0.2191207557053183 1.0 1.0 0.5360086488121985 0.1967440299635801 +Organelle membrane contact site 10 18 2.2277648291497028 0.0258962013513055 6.817961165048544 16.400485436893202 0.815819301321945 0.3904411977369264 3.451940177462974 2.047328298639296 1.2919706717077657 0.3464717655445403 0.2560967026301567 0.1583124314184509 0.2921659829416722 0.2102212619820596 0.2412627059282133 +Cytochrome complex 6 18 2.2143373690694794 0.0268055798064925 6.021844660194175 16.08495145631068 1.0267019648816196 0.2321293206617183 2.9315837025395948 1.6175814223208935 1.624269406530766 0.2919563386676546 0.0081826700022156 0.1330370821365251 0.0027797273347076 0.0051006501172469 0.000378511976274 +Transporter complex 22 58 2.2109952602764578 0.0270361652801949 16.033980582524272 55.199029126213595 0.256193630237002 0.358562058071074 7.704418772430675 7.665912382074106 1.666161547187811 0.3440522205931707 0.0008926728674471 0.163845303256872 0.0574462537203819 0.0033642645861238 0.0008366923766694 +Late endosome 15 71 2.2102043857868767 0.0270909807386043 15.655339805825244 65.18203883495146 0.1482522199608934 0.3683478922291265 6.675389202214119 9.543379127098556 1.7080817701484334 0.368772234437858 0.0289986638641258 0.266182518567592 0.0508871667839199 0.0118512843304504 0.0419043615161848 +Er ubiquitin ligase complex 4 7 2.175965470920963 0.0295578425472777 2.0970873786407767 4.70873786407767 0.8764155338390741 0.2924583478733635 1.3110031963021629 1.3573322490080977 1.246637632205364 0.2924172085124771 0.2469542868995065 1.0 1.0 1.0 0.0106255777102749 +Golgi lumen 2 5 2.1592790411857408 0.0308285251410829 1.745679012345679 4.548148148148148 1.1368717941323 0.2457507117503182 1.2159484823715767 1.4039724163790972 1.161880305109492 0.2643265801751675 0.0590764560136037 0.1457663642848915 0.0390334649397651 0.0424141111811751 0.2023846543655014 +Pore complex 3 10 2.1218265019409697 0.0338523102656693 3.2111650485436893 8.830097087378642 1.029129610796519 0.2182996080526768 1.893158762220583 0.772882004264421 1.343874754683687 0.2717215815078918 0.0109888256406173 0.0030581061915538 0.0117676307173903 0.0075942890928168 0.0079370796506279 +Tim23 mitochondrial import inner membrane translocase complex 3 6 2.041180490538688 0.0412328901556116 2.2694174757281553 6.342233009708738 1.5180442383336388 0.125307709046494 1.369833329272529 0.8106469094037756 1.2674744491900518 0.2021471972412396 0.003018350944599 0.0526645480715484 0.0049445172385496 0.0020533662966424 0.00138858926748 +External side of plasma membrane 4 20 2.010216848409344 0.0444082429593575 6.856796116504855 22.03640776699029 0.7617836494895279 0.3205100812766187 3.0547396608098576 3.343757364022431 1.3549821177336052 0.303342613906597 0.1751485579043305 1.0 0.6501318995178187 0.1174555869657141 0.5924456265910939 +Microbody lumen 7 24 1.9737970571862316 0.0484048236082186 5.252427184466019 20.393203883495147 -0.4071006494584963 0.4586879567538232 2.7614490588986196 2.6330152576050585 1.0287152065016216 0.2976018505964726 0.6503566301882355 0.1665759675679584 0.3060304729743218 0.6000617657406979 0.0003278164997314 +Organelle envelope lumen 18 38 1.967339667672608 0.0491440647944521 11.436893203883496 36.55339805825243 0.6276066761486734 0.4428242266058088 4.702137301503097 3.7796803567009714 1.1382138566471218 0.3469405856623805 0.1793873999536424 1.0 1.0 0.1272831365513204 0.0001009539620315 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f262856f5ae00b23f3c51baede68591b71ccfc63 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 909, + "title": "Average number of proteins per term", + "value": 30.231023102310232 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3fee490490586d625b5b0b8a28bd03b90a2aec2e --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..842c4123e48ee892efbdaa9e949036d78c0ce47a --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,327 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Nuclear outer membrane endoplasmic reticulum membrane network 0.5507845892130885 7.876099416523562 3.3775952564561378e-15 3.0711430881139186e-12 3.0711430881186297e-12 314 Q9BQE5,Q6UX53,P57088,P24390,Q8N0U8,Q15392,Q9H0U3,Q8N511,Q99720,Q14849,Q9UGP8,O75844,Q13190,Q9HD20,P43307,P30519,O95864,A1L0T0,Q8TB61,Q9Y6I9,Q8NHH9,P09601,Q14108,O75477,O60725,Q6IAN0,Q9NXE4,Q9UL01,Q8NFQ8,Q99523,O95470,Q6NTF9,Q15800,Q13438,O43731,O15260,Q9BUR5,Q9Y282,O60762,P51648,Q9UBM7,Q8TCJ2,Q8NAT1,Q15629,Q8IV08,O95487,Q14534,Q9H490,Q96G23,Q9Y320,Q9NZ01,Q8TD16,Q9P2W9,O95197,P38435,P07099,O00767,O00264,Q9UM00,Q86XL3,P37268,P67812,Q9NZ08,Q96N66,Q96GC9,O43292,Q16850,Q03519,Q6NUM9,Q03518,Q14739,Q96PC5,P16435,Q9Y5M8,P04439,P35610,Q07065,Q06136,O14678,Q53GQ0,Q86UE4,Q9NP80,Q9UBU6,O00560,P16615,P35613,Q14457,Q2TAA5,Q8TCT9,O15269,Q9P035,Q5BJF2,O15270,P14625,Q9BRR6,Q9Y4P3,P22059,Q96KC8,O43852,P61586,P42345,Q96RL7,Q9NQC3,P48651,Q9NUQ2,Q9BUN8,P04844,P01889,Q96HY6,Q96A33,O60568,O76062,Q9UBV2,P10321,P51571,Q6P179,Q9BU23,O14975,P50402,P46977,Q5T9L3,Q6NUQ1,Q86YN1,Q9BZF1,Q10472,Q70UQ0,Q9Y3B3,O75845,O43865,O76024,Q15904,Q9BT22,P27544,Q8NF37,Q8N5M9 135 +Endoplasmic reticulum 0.5102963008134773 7.645160472935916 2.0868490451831895e-14 1.8970366820535452e-11 9.485183410357596e-12 488 Q9BQE5,P30536,Q6UX53,P57088,P80303,P24390,P52789,P61916,Q8N0U8,Q15392,Q9H0U3,Q8N511,Q99720,Q14849,Q9UGP8,P04062,O75844,Q13190,Q32P28,Q9HD20,P43307,Q12768,P30519,O95864,O43681,A1L0T0,Q8TB61,Q9Y680,Q9Y6I9,Q8NHH9,P09601,Q14108,O75477,O60725,Q6IAN0,Q5VYK3,Q9H6S0,Q9NXE4,Q9UL01,Q9BRK5,Q9H223,Q8NFQ8,Q99523,O95470,Q6NTF9,Q15800,O75718,P46776,Q13438,O43731,O15260,O15173,Q9BUR5,Q92542,Q9Y282,P05023,Q9HD47,O60762,O75503,P51648,Q9UBM7,O15118,Q8TCJ2,Q14BN4,Q8NAT1,Q15629,Q8IV08,O95487,Q14534,Q9H490,Q96G23,Q9Y320,Q9NZ01,Q9P2W9,O95197,Q14257,P38435,P07099,O00767,O00264,Q9UM00,Q9UQB8,Q9HCU5,Q86XL3,Q5VV42,P37268,Q8IZP0,P67812,P00367,P49257,Q92530,Q9NWM8,Q9NUU6,Q9NZ08,Q96N66,O60506,Q96GC9,Q9NPA0,O43292,O43390,P51572,Q969H8,Q9BTY2,P05067,Q15041,Q16850,Q03519,Q6NUM9,Q7Z3C6,Q03518,Q92791,Q14739,P27824,Q96PC5,Q9UBS4,P10619,O60476,P16435,Q6ZXV5,Q9Y5M8,P27635,Q12907,Q96LJ7,Q9UNW1,Q8TBX8,P04439,Q9UHQ9,Q02818,P48449,Q13510,P35610,Q07065,Q9Y394,Q8IUR0,Q06136,O14678,Q53GQ0,Q86UE4,Q9NP80,Q9UBU6,O00560,P62753,P27695,O94832,Q99442,P16615,Q96S66,P35613,Q14457,Q2TAA5,Q8TCT9,Q99797,O15269,Q9P035,Q5BJF2,O15270,P14625,Q9BRR6,Q9Y4P3,P13674,P22059,Q96KC8,O43852,P61586,O95302,P42345,Q96AY3,Q96RL7,Q9NQC3,P48651,Q9NUQ2,Q9BUN8,P04844,P01889,Q96HY6,Q96A33,O60568,O76062,Q13641,Q9UBV2,P10321,O15460,P51571,Q6P179,Q9BU23,O14975,P50402,P46977,O95881,Q5T9L3,P42858,Q6NUQ1,Q86YN1,Q9BZF1,Q10472,Q70UQ0,Q8IY95,Q9Y3B3,O75845,O43865,O00584,O76024,Q15904,Q9BT22,P27544,Q08431,Q8NF37,Q8N5M9 208 +Organelle subcompartment 0.5066615847327546 7.443225913301841 9.82558432878238e-14 8.931547054464758e-11 2.977182351621061e-11 380 Q9BQE5,Q6UX53,P57088,P24390,Q8N0U8,O60512,Q15392,Q9H0U3,Q8N511,Q99720,Q14849,Q9UGP8,P04062,O00461,O75844,Q13190,Q9HD20,P43307,Q16706,P30519,O95864,A1L0T0,Q8TB61,Q9Y6I9,Q8NHH9,P09601,Q14108,O75477,O60725,Q6IAN0,Q5VYK3,O15127,Q9BTU6,Q9NXE4,Q9UL01,Q8NFQ8,Q99523,O95470,Q6NTF9,Q15800,Q13438,O43731,O15260,Q9BUR5,Q9Y282,O60762,Q9NPR9,P51648,Q9UBM7,Q8TCJ2,Q8NAT1,Q15629,Q8IV08,O95487,Q14534,Q9H490,Q96G23,Q9Y320,Q9P2W9,O95197,P38435,P07099,O00264,Q86XL3,P37268,P67812,Q9NZ08,Q96N66,Q96GC9,O43292,P05067,Q16850,Q03519,Q6NUM9,Q03518,Q14739,Q96PC5,P16435,Q9Y5M8,P04439,P35610,Q07065,Q06136,O14678,Q53GQ0,Q86UE4,Q9NP80,Q9UBU6,O00560,Q8TBA6,P16615,P35613,Q14457,Q2TAA5,Q8TCT9,O15269,Q10713,Q9P035,Q5BJF2,O15270,P14625,Q9BRR6,Q9Y4P3,P22059,Q96KC8,O43852,P61586,Q96L58,P42345,Q96RL7,Q9NQC3,P48651,Q9NUQ2,Q9BUN8,P04844,P01889,Q4J6C6,Q96HY6,Q96A33,O60568,O76062,Q9UBV2,P10321,P51571,Q6P179,Q9BU23,O14975,P50402,P46977,Q5T9L3,Q6NUQ1,Q86YN1,Q9BZF1,Q10472,Q70UQ0,Q8NBN3,Q9Y3B3,O75845,O43865,O76024,Q15904,Q9BT22,P27544,Q8NF37,Q8N5M9 145 +Organelle inner membrane 0.5743159400956611 7.08763072855168 1.364274109903568e-12 1.2401260741342328e-09 3.1003151872558585e-10 242 Q99623,Q14197,Q69YU5,Q9H061,Q7KZN9,Q9UBX3,Q70HW3,O95168,Q9Y2R0,O60830,O43676,Q16134,Q99720,Q9BQ95,P00403,O75844,P23786,Q9UDX5,Q9Y619,Q9H2V7,O75964,P43304,Q9H2D1,Q9Y5J7,Q13505,O43615,Q9BSK2,P14406,Q6NUK1,P62995,P03886,Q9UDW1,P43243,Q99595,Q6DKK2,Q9NP92,Q9NVH1,Q9BUR5,O96000,Q5XKP0,Q9Y584,Q9Y5L4,Q14728,P36551,P24539,Q9Y6C9,Q13423,Q567V2,Q5SNT2,O14949,Q8IXM6,Q9BQT8,Q9P0J0,Q9H9P8,P53701,Q86Y39,P06576,O75438,Q9H1E5,P82933,Q9UJS0,Q15070,P21912,Q6UXV4,O75746,Q9Y5J9,P82663,Q02978,Q9BYC9,Q96BW9,O14925,Q9NX63,Q00325,P12235,P56385,P09001,Q14739,Q6P4A7,O76031,Q5T9A4,Q96CU9,Q9Y512,Q10713,P08574,Q9Y6M9,Q9NPL8,P13073,Q8IYU8,P14854,O94901,O60313,O76062,P51970,O95202,Q96NB2,O95831,O75306,P12236,Q9H2W6,Q9UH99,P50402,P22830,Q9NVI7,Q9BRJ2,Q9NQ50,Q709F0,O43772,Q9NVS2,Q9UG56,Q16891,Q7Z7H8,Q9NUT2 112 +Mitochondrial envelope 0.49967161052211 7.003660090137495 2.493606762786998e-12 2.2666894538072667e-09 4.5333789127467614e-10 320 Q99623,P30536,Q14197,P52789,Q9NS69,O14786,P21796,Q69YU5,Q9H061,Q9UBX3,O43169,P45880,Q70HW3,Q7KZN9,O95168,Q9Y2R0,O60830,O43676,Q16134,Q9BQ95,P00403,P23786,Q9UDX5,Q9Y619,Q9H2V7,O75964,Q9H2D1,P43304,Q9Y5J7,Q13505,P09601,O43615,Q9BSK2,P14406,Q6NUK1,P03886,Q9UDW1,Q99595,Q6DKK2,Q9NP92,Q9NVH1,Q96A26,Q9BUR5,Q8N4H5,O96000,Q8WY22,Q5XKP0,Q07820,Q9Y584,Q9Y5L4,Q9Y320,Q8NAN2,P36551,P24539,O00264,Q9Y6C9,Q13423,Q567V2,O14949,Q9BQT8,Q9P0J0,Q9H9P8,Q8N2A8,P53701,Q86Y39,P06576,O75438,Q9BXK5,P82933,Q9UJS0,Q15070,Q9NR28,P21912,Q6UXV4,O75746,Q9Y5J9,P82663,Q02978,Q9BYC9,Q96BW9,O14925,Q9NX63,Q00325,P12235,P56385,P09001,Q9P032,Q6P4A7,P57105,O76031,Q5T9A4,Q9NP80,Q96CU9,Q9Y512,Q14457,Q10713,P08574,O15228,Q9Y277,Q9Y6M9,Q9NPL8,Q9NZJ7,P13073,Q8IYU8,Q9BYT8,P42345,Q96AY3,Q96RL7,Q9NUQ2,P14854,O60313,P51970,Q8TB36,Q9NZ45,O95202,Q96NB2,O95831,O75306,P12236,Q9H2W6,P22830,Q9NVI7,Q9BRJ2,Q9NQ50,Q709F0,O43772,O00584,Q9NVS2,Q9UG56,Q16891,Q9NQG6,Q7Z7H8,Q9NUT2 133 +Envelope 0.4684093713340029 6.719495697957969 1.8235456792846856e-11 1.6576030996466525e-08 2.7626718556162992e-09 493 Q99623,P30536,Q14197,P57088,P80303,P52789,Q9NS69,O14786,P21796,Q69YU5,Q9H061,Q9UBX3,O43169,P45880,Q70HW3,Q7KZN9,O95168,Q9Y2R0,O60830,O43676,Q16134,Q99720,Q9BQ95,P00403,O75844,P23786,Q15154,Q6ZRP7,Q9UDX5,Q99567,Q7Z3B4,Q9Y619,Q9H2V7,O75964,Q9H2D1,P43304,Q9Y5J7,Q13505,P09601,O43615,Q9BSK2,P14406,Q6NUK1,P62995,P03886,Q9UDW1,P43243,Q99595,Q9NXE4,Q6DKK2,Q8NFQ8,Q9NP92,Q9C0E2,Q99523,Q9BTX1,Q8N1F7,Q9NVH1,Q96A26,Q9BUR5,O15173,Q8N4H5,O96000,Q8NFH4,Q9UBM7,O15118,Q8WY22,Q5XKP0,P52294,Q07820,Q9Y584,Q9Y5L4,Q9Y320,Q14728,Q8TD16,Q9HB71,Q8NAN2,P36551,P24539,O00264,Q9Y6C9,Q13423,Q567V2,Q5SRE5,Q5SNT2,O14949,Q8IXM6,Q9BQT8,Q9P0J0,P35658,Q9H9P8,Q8N2A8,P53701,Q86Y39,P06576,Q9H1E5,O75438,Q9BXK5,P82933,Q9UJS0,Q9NUU6,Q15070,Q9NR28,P21912,Q6UXV4,O75746,Q9Y5J9,P82663,Q02978,Q9BYC9,Q96BW9,O14925,P05067,Q9NX63,Q6NUM9,Q00325,P12235,P56385,P09001,Q14739,Q9P032,Q9H4A6,Q6P4A7,P57105,O76031,Q5T9A4,Q86UE4,Q9NP80,O00560,Q96CU9,Q9Y512,Q14457,Q10713,Q9P035,Q5BJF2,P08574,O15228,Q9Y277,P07437,Q96KC8,Q9Y6M9,Q9NPL8,O15397,Q9NZJ7,P13073,P41208,Q8IYU8,Q9BYT8,P42345,Q96AY3,Q96RL7,Q9NQC3,Q9NUQ2,P14854,O94901,O60313,O76062,P51970,Q8TB36,P67809,Q9NZ45,O95202,Q96NB2,O95831,O75306,P12236,Q9H2W6,Q9UH99,P50402,P22830,Q9NVI7,Q9BRJ2,Q8N201,Q9BZF1,Q9NQ50,Q709F0,O43772,O00584,Q9NVS2,Q9UG56,Q12769,Q16891,Q9NQG6,Q7Z7H8,Q9NUT2 184 +Intrinsic component of organelle membrane 0.6175168256412789 5.973041115580074 2.328711795463094e-09 2.1167967850321833e-06 3.0239986042642177e-07 124 P20020,O76062,P57088,Q8TB36,P10321,O00767,Q8WVX9,Q99442,Q9Y2R0,O60830,Q16134,Q9UM00,Q9HCU5,Q9Y512,Q5SNT2,Q96K12,Q96NB2,Q86XL3,O75844,Q9H9P8,Q8TCT9,Q9P035,Q6ZRP7,L0R6Q1,O14975,Q9UH99,Q15070,Q8TB61,Q9Y4P3,Q13505,Q9Y287,Q6UXV4,Q5T9L3,Q9NPA0,O43292,P51572,Q86YN1,O43808,P42892,O14925,Q99595,Q15041,Q9NX63,Q6NTF9,O95470,Q03519,Q00325,P12235,Q03518,Q9NVH1,P27824,Q14739,Q9BUR5,Q9UG56,O76024,Q9Y282,Q9NQC3,Q6P4A7,Q96A33,Q16891,Q9BUN8,Q9UBM7,P13473,O15118,P57105,O94901,P01889,Q5XKP0,Q15629,P04439,Q8IWA4,O43505,Q9H490,Q9NZ01 74 +Vacuole 0.4780143877900905 5.236675304489291 1.634949484246903e-07 0.0001486058773205 1.8577113514869063e-05 216 O14678,P61916,Q9UIQ6,P38435,O00560,Q15165,P51798,P06865,P06280,Q13107,P50897,Q8NCG7,Q9H0U3,Q8N511,Q8TAF3,Q14849,P08236,P04062,Q14457,O14773,P07602,Q5BJF2,Q8WTV0,P33176,P16278,Q13277,Q9H2V7,Q01085,Q9Y487,Q92820,Q9Y5Z4,Q9UM22,O43681,Q8NHP8,Q9Y6I9,P10253,Q9UHG3,P07437,Q14108,Q96GC9,Q15043,P42858,P17900,Q969Q5,P42892,Q9BTY2,Q9BTU6,P15586,P42785,Q9NZJ7,Q99519,Q8IY95,Q9NX40,Q99523,P54802,Q9H7Z7,Q16625,Q8NCC3,Q93050,Q9Y2T2,O00584,Q9NQX7,O15260,P10619,P42345,Q96RL7,O75503,P13473,O15118,P04844,P11117,Q8TBX8,Q8IV08,Q8NF37,Q13510,Q07065 76 +Lysosomal lumen 0.7807423633187427 4.761029714118096 1.926076842906354e-06 0.0017492737703552 0.0001945337611336 36 P38435,P06865,P06280,P50897,P08236,P04062,O14773,P07602,P16278,Q9UM22,Q8NHP8,P10253,Q14108,P17900,Q9NZJ7,Q99519,P15586,P54802,P10619,P13473,Q8IV08,Q13510 22 +Intrinsic component of plasma membrane 0.5759636492668494 4.7268138129398345 2.2807020818582657e-06 0.0020710130434979 0.000207315819241 78 P20020,O76062,Q13641,Q8NAN2,O14786,Q9UIQ6,P36551,P11279,O96005,O00560,P10321,O00264,P16615,P53985,P35613,P30825,Q9H0U3,Q99797,P11166,Q8WTV0,O95864,Q9UJS0,Q9NR28,O43657,Q15043,P51572,P55011,Q02978,Q9BTU6,P05067,Q9Y4G8,Q00325,P12235,P27824,Q92542,P78310,P05023,P05141,O15118,P01889,Q14BN4,P04439,O60637 43 +Intrinsic component of endoplasmic reticulum membrane 0.6443510257076169 4.544262311446566 5.512797346174381e-06 0.0049986117520069 0.0004354553891719 54 P57088,Q9NZ01,P10321,O00767,Q99442,Q9UM00,Q9HCU5,Q86XL3,Q8TCT9,O75844,Q9P035,O14975,Q8TB61,Q9Y4P3,Q9NPA0,O43292,P51572,Q86YN1,Q15041,Q03519,Q6NTF9,O95470,Q03518,P27824,O76024,Q9Y282,Q9NQC3,Q9BUN8,Q9UBM7,P01889,P04439,Q15629,Q96A33,Q9H490,O76062 35 +Vacuolar lumen 0.6130249153500413 4.53543140492151 5.74858599566852e-06 0.0052118506204529 0.0004354553891719 66 P38435,O00560,P06865,P06280,P50897,P08236,P04062,O14773,P07602,P16278,Q92820,Q9Y5Z4,Q9UM22,Q8NHP8,P10253,P07437,Q14108,P17900,Q9BTY2,Q9NZJ7,Q99519,P15586,Q9H7Z7,P54802,P10619,P13473,P11117,Q8IV08,Q13510 29 +Mitochondrial protein containing complex 0.4640375069200739 4.292116407222438 1.7697811957928522e-05 0.0159587414877627 0.0012327200809952 159 Q99623,Q14197,P51970,P11177,Q9NS69,P21796,P24539,Q96CU9,O95168,O60830,O43676,Q9Y512,Q567V2,O14949,P00403,Q9P0J0,O75306,P12236,Q86Y39,P06576,O75438,P08574,Q9H2W6,O75964,P82933,Q9Y5J7,Q13505,P21912,Q6UXV4,Q9BRJ2,P14406,Q9Y5J9,Q9Y6M9,Q9BYC9,Q9NQ50,P03886,Q9UDW1,Q15118,O14925,Q99595,Q9NP92,P13073,Q9NX63,P12235,P56385,P09001,Q8IYU8,Q9NVH1,Q9NVS2,Q9BUR5,Q8N4H5,O96000,Q16891,P21953,P05141,P14854,Q5XKP0,Q9Y584,Q7Z7H8,O00411,O76031,Q9Y5L4 62 +Inner mitochondrial membrane protein complex 0.5461316436309498 4.276496103666513 1.898578782610905e-05 0.017110174491326 0.0012327200809952 76 Q99623,P51970,P24539,Q96CU9,O95168,O60830,O43676,Q9Y512,O14949,P00403,Q9P0J0,O75306,P12236,Q86Y39,P08574,O75438,P06576,O75964,Q9Y5J7,Q13505,P21912,Q6UXV4,P14406,Q9Y6M9,P03886,Q9UDW1,O14925,Q99595,P13073,Q9NX63,Q8IYU8,Q9NVH1,Q9BUR5,O96000,Q16891,P14854,Q5XKP0,Q9Y584 38 +Outer membrane 0.5101082520859224 4.188399356602242 2.8092884452934896e-05 0.0252134847434246 0.0017024287978479 93 Q99623,P30536,P52789,Q8TB36,Q9NS69,Q8NAN2,P21796,O43169,P45880,O00264,Q9Y6C9,Q9NZ45,Q9Y512,Q99720,Q8N2A8,P50402,Q9Y277,Q13505,P09601,Q9NXE4,Q9NZJ7,Q6NUM9,Q9NVH1,Q9BUR5,P42345,Q8N4H5,Q96RL7,Q16891,Q9NUQ2,Q9UBM7,P57105,Q8WY22,Q9NQG6,Q5XKP0,O60313 35 +Mitochondrion 0.3516707804496277 4.017363481905352 5.885290961660239e-05 0.0520929870457207 0.0031468996965583 641 Q99623,P30536,O75874,Q14197,P52789,P11177,Q9NS69,O14786,P21796,P48735,Q69YU5,Q9H061,Q9UBX3,O43169,P45880,Q70HW3,Q7KZN9,O95168,Q9Y2R0,O60830,O43676,Q16134,Q14849,Q9BQ95,P00403,P23786,Q9UDX5,Q9Y619,Q9H2V7,O75964,Q9Y2W6,Q9H2D1,Q9Y5Z4,P43304,P28288,Q9Y2S7,Q9Y5J7,Q13505,P09601,O43615,Q9BSK2,P14406,Q6NUK1,Q9H2U1,Q3SXM5,P03886,Q9UDW1,Q9BTU6,P00374,Q9NWU1,Q99595,Q6DKK2,Q9NP92,Q5JRX3,Q9NPH0,Q9NVH1,Q8NBX0,Q96A26,Q9BUR5,Q92542,Q8N4H5,O96000,Q8WY22,Q5XKP0,Q07820,Q9Y584,O14929,Q16836,Q9NR77,Q9Y5L4,Q9Y320,Q8NAN2,Q5JPH6,P36551,P24539,Q15165,O00264,Q9Y6C9,Q13423,Q567V2,O14949,Q9BQT8,Q9P0J0,P07900,Q9H9P8,Q8N2A8,Q8TAE8,P53701,Q86Y39,Q5T2R2,P06576,O75438,P00367,Q9BXK5,P82933,Q9UJS0,Q15070,Q9NWS8,Q96EK5,Q9NR28,P21912,Q6UXV4,O75746,Q9Y5J9,O43292,P51572,P82663,Q9NVH6,Q02978,Q9BYC9,Q96BW9,O14925,Q68CZ6,Q9NX63,Q7Z3C6,Q00325,P12235,P56385,P09001,Q9NUJ1,Q9Y305,Q9P032,Q9H4A6,Q86YH6,P16435,Q6P4A7,Q07021,P41247,P21953,P57105,P05141,Q9UHQ9,O00411,O76031,P35610,Q5T9A4,Q9NP80,P05091,Q96CU9,P35613,Q9Y512,Q14457,Q99797,O43572,Q10713,P08574,Q9BWD1,Q9H773,O15228,Q9Y277,P13674,Q9Y6M9,Q9NPL8,Q15118,Q9NZJ7,P13073,Q8IYU8,Q9BYT8,P42345,Q96AY3,Q96RL7,Q9NUQ2,P14854,Q8N3Z3,O60313,P51970,Q15120,Q8TB36,Q9NZ45,O95202,Q96NB2,O95831,O75306,P12236,Q9H2W6,P22830,Q96EY8,Q9NVI7,Q9BRJ2,O75648,Q9NQ50,Q709F0,Q9NUQ9,Q9H7Z7,O43772,Q7L592,P23378,O00584,Q9NVS2,Q9BW92,Q9UG56,Q9Y2Z2,Q16891,Q9NQG6,Q7Z7H8,Q9NUT2 196 +Golgi apparatus 0.3573464029425814 3.9399042253963334 8.151414521440081e-05 0.0714205912151483 0.0041164643333272 326 P80303,P24390,Q92974,O60512,P50897,Q15392,P04062,O00461,Q13190,Q16706,Q6ZRP7,L0R6Q1,Q96SU4,P16278,Q969S3,Q8TB61,Q14108,Q5VW38,Q5VYK3,O15127,Q9BTU6,P54646,Q9NXE4,Q9UL01,Q9BRK5,Q99523,Q6NTF9,Q9Y2T2,Q8IZA0,O43731,O15260,Q9BUR5,Q92542,Q9Y282,P46934,Q9NPR9,O75503,O15118,Q8IV08,Q7LGA3,Q9P2W9,O95197,Q9UQB8,O14773,Q8N2A8,Q8N4A0,Q9H8H2,Q9Y287,P05067,Q96PU5,Q9NX40,Q93050,Q9NQX7,O60476,P04439,Q02818,Q92544,Q8TBA6,Q92896,P35613,P06280,Q14457,Q10713,P22059,O43852,Q96L58,Q13535,P42345,Q96RL7,P01889,Q4J6C6,O60568,P10321,Q5T9L3,P42858,Q10472,O14744,Q8IY95,Q8NBN3,Q9Y3B3,Q9H7Z7,P25398,Q8NF37 83 +Membrane protein complex 0.3700240996933168 3.914084415553532 9.074788638230302e-05 0.0791826429979456 0.0043415699327112 302 Q99623,Q9NS69,P21796,P51798,P45880,O95168,O60830,O43676,Q9H0U3,Q9C0H2,Q8N511,P00403,Q9UGP8,Q13190,O75964,Q9Y5J7,Q13505,P14406,P03886,Q9UDW1,Q99595,Q6NTF9,Q13438,Q9Y2T2,Q9NVH1,Q9BUR5,Q92542,Q8N4H5,P05023,O96000,Q8TCJ2,Q5XKP0,Q9Y584,O95487,Q9H490,Q9P2W9,P24539,O14949,Q9P0J0,Q4KMQ2,Q86Y39,P06576,O75438,P67812,Q9Y487,O95249,Q9NR28,P21912,Q6UXV4,Q9NPA0,O43292,O14925,Q15041,Q9NX63,Q03519,Q6IQ23,P12235,Q03518,Q93050,Q9Y5M8,P04439,O14678,Q53GQ0,Q9UBU6,O00560,Q96CU9,Q9Y512,Q14457,Q8TCT9,O15269,P08574,O15270,Q9Y277,Q9Y6M9,P13073,Q8IYU8,Q9BUN8,P14854,P04844,O94901,P01889,P51970,Q9UBV2,P10321,P51571,O75306,P12236,Q13277,Q9UH99,P46977,Q07666,Q9Y3B3,Q16891,Q15904,Q9NUT2 95 +Vacuolar membrane 0.4508110774343113 3.7012646304597454 0.0002145275967702 0.177187151295624 0.0062927154065817 123 O14678,Q9UIQ6,P51798,Q8NCG7,Q9H0U3,Q8N511,Q14849,P04062,P07602,Q8WTV0,P33176,Q9H2V7,Q9Y487,Q9Y6I9,P10253,Q14108,Q96GC9,Q15043,P42892,Q9BTU6,Q9NZJ7,P42785,Q99519,Q8IY95,Q99523,Q16625,Q93050,Q9Y2T2,Q9NQX7,O15260,P10619,P42345,Q96RL7,O75503,P13473,O15118,P04844,P11117,Q8IV08,Q8NF37,Q07065 41 +Secretory granule membrane 0.5083564304119417 3.6462662420510887 0.0002660782983392 0.214863237348622 0.0073292476724355 72 Q5T9A4,P10321,O00264,P35613,Q4KMQ2,P07602,O14975,Q13277,P30519,P10253,Q969Q5,P61586,Q9NZJ7,P42785,Q93050,Q9NQX7,O15260,P13473,P01889,Q08431,Q8NF37,Q07065 22 +Respirasome 0.5631693575364689 3.6297553917079575 0.0002836899252656 0.2273357930235943 0.0075845335901896 45 O75306,P14406,P51970,Q9Y6M9,Q86Y39,P03886,P08574,Q9UDW1,Q96CU9,Q7KZN9,P14854,Q13423,Q6DKK2,P13073,O43676,O14949,P00403,Q9P0J0 18 +Golgi membrane 0.4353896270533233 3.612489721414312 0.0003032711314481 0.2409709807911491 0.0078687776264934 136 Q7LGA3,Q86Y82,Q9P2W9,O95197,P24390,P10321,Q8TBA6,Q92896,Q96S66,O60512,Q9UM00,P35613,Q15392,P49755,Q08379,O00461,Q13190,Q10713,Q16706,Q6ZRP7,L0R6Q1,P11166,Q15363,Q9BVK6,Q8N4A0,O95249,P49257,Q8TB61,Q14108,Q9Y287,P22059,O15258,Q5T9L3,P51572,Q9NTJ5,Q9H9S5,Q10472,Q9NXE4,Q9UL01,Q96L58,Q8NBN3,Q9Y3B3,Q6NTF9,Q7Z3C6,Q9H7Z7,Q8IZA0,P0CG08,Q9BUR5,O43731,O15260,Q9H4A6,P42345,Q9Y282,O60476,Q8NDZ4,Q8NF37,Q12907,P01889,P04439,Q10471,Q8IV08,O43505 62 +Endoplasmic reticulum lumen 0.5328264454974246 3.5575783105808703 0.0003742895366938 0.2884381077706582 0.0085057297213672 61 Q14257,O15460,Q6P179,Q32P28,O14975,P14625,Q9NWM8,O43681,O95881,Q9Y680,Q9NZ08,P13674,Q969H8,O43852,Q9BTY2,P05067,O75718,Q13438,O00584,P27824,Q9UBS4,O76024,Q96AY3,O60568,Q08431,Q02818,Q07065 27 +Intrinsic component of mitochondrial membrane 0.5586314196480163 3.486659448875019 0.0004890937297539 0.3589802158127041 0.0100873874660646 43 Q8TB36,Q9Y2R0,O60830,Q9Y512,Q16134,Q96NB2,Q9H9P8,Q15070,Q13505,Q6UXV4,O14925,Q99595,Q9NX63,Q00325,P12235,Q9NVH1,Q9UG56,Q9BUR5,Q16891,Q6P4A7,P57105,Q5XKP0 22 +Endocytic vesicle membrane 0.5792405497747566 3.431156066516371 0.0006010147186485 0.4210195800293579 0.0113817162344078 40 Q8WTV0,P10321,P13473,Q9Y487,P01889,Q93050,P04439,Q03519,Q15907,Q03518,Q14108 11 +Azurophil granule 0.4926821250882016 3.378595147720921 0.0007285721548262 0.4844461207119916 0.0135157569130011 70 P61916,O00560,P06865,P06280,Q9H0U3,P08236,P07602,Q13277,P16278,Q92820,Q9Y5Z4,P10253,P07437,P17900,Q9BTY2,Q9NZJ7,P15586,P42785,Q9H7Z7,O00584,Q9NQX7,P10619,O15260,P13473,Q8NF37,Q07065 26 +Intrinsic component of mitochondrial inner membrane 0.6433154059709677 3.353365767925465 0.0007983512749325 0.5161552293317173 0.0142827708626827 30 Q9UG56,Q9H9P8,Q9BUR5,Q00325,Q13505,Q16891,Q6P4A7,O14925,Q99595,Q9Y2R0,O60830,Q9Y512,Q16134,Q15070,Q5XKP0,Q96NB2,Q6UXV4,Q9NVH1 18 +Nuclear envelope 0.3774297999967274 3.105215067624758 0.0019014071632574 0.8227199110164665 0.0297996398517423 180 Q8TD16,P57088,P80303,Q9HB71,Q86UE4,P67809,O00560,Q5SRE5,Q5SNT2,Q99720,Q8IXM6,O75844,Q15154,Q9P035,Q6ZRP7,Q5BJF2,Q7Z3B4,Q99567,Q9H1E5,Q9H2V7,Q9UH99,P50402,P07437,Q8N201,Q96KC8,P62995,Q9BZF1,O15397,P43243,P05067,Q9NXE4,Q8NFQ8,Q9C0E2,Q99523,Q6NUM9,P41208,Q9BTX1,Q8N1F7,Q14739,P42345,O15173,Q12769,Q9NQC3,Q8NFH4,Q9NUQ2,Q9UBM7,O15118,O94901,P52294,O76062,Q14728 51 +Platelet dense granule 0.9136522753792308 3.0279035902374436 0.0024625663770763 0.893672738032687 0.0342136464693576 2 P13473 1 +Endoplasmic reticulum palmitoyltransferase complex 0.9130688448074676 3.025264332820241 0.0024841591495903 0.8957444373854125 0.0342136464693576 2 O15269 1 +Palmitoyltransferase complex 0.9130688448074676 3.025264332820241 0.0024841591495903 0.8957444373854125 0.0342136464693576 2 O15269 1 +Endocytic vesicle 0.4214621785059224 2.971971484985489 0.0029589416410409 0.932367396972395 0.0363469993473812 86 P10321,Q15907,Q14457,O00461,Q8WTV0,P33176,P14625,Q9Y487,Q14108,Q969Q5,Q5VYK3,P08670,Q03519,Q16625,Q03518,Q93050,P42345,P13473,P01889,P04439 20 +Nuclear inner membrane 0.667986639988726 2.963382369677396 0.0030427833405677 0.9373446755626388 0.0368785340876809 23 O75844,O76062,P62995,P43243,Q9H1E5,Q9UH99,P50402,O94901,Q99720,Q8IXM6,Q14739,Q14728 12 +Histone pre mrna 3 end processing complex 0.88564760793465 2.9002849341470265 0.0037282358424186 0.9664694917207796 0.043448286932802 2 O60506 1 +Ciliary rootlet 0.8763127187864587 2.857317215046067 0.004272386258076 0.9795938495674092 0.0491594823872291 2 P05067 1 +Microbody 0.4688061007299207 2.8317932617624195 0.0046287765699999 0.985261998418566 0.0513116817332919 60 O75874,O14678,Q8TB36,Q9NP80,P48735,O14734,Q13315,Q96K12,O15254,O14975,P28288,O15228,Q15067,Q2T9J0,Q6IAN0,Q709F0,P08670,A8MXV4,Q8N4Q0,P51648,Q9NQG6,Q9NR77 22 +Phagocytic vesicle 0.4916307270302751 2.750266227227982 0.0059546863342998 0.995612474743752 0.062216205492857 42 P42345,P10321,P13473,Q9Y487,P01889,P08670,P04439,Q03519,Q15907,Q03518,Q93050,Q14457 12 +Endoplasmic reticulum golgi intermediate compartment membrane 0.6082712738317206 2.7442033226140476 0.0060657955335183 0.9960363853922118 0.0623454888980621 26 P24390,P49755,Q8N511,Q08379,Q13190,Q9BVK6,Q15363,O15533,P49257,Q96GC9,P51572,Q10472,Q9Y3B3,Q03519,Q03518,O15260,Q9Y282,Q15904,Q12907 19 +Atp binding cassette abc transporter complex 0.8515169194865772 2.7421291371658767 0.0061042337864989 0.996173302719318 0.0623454888980621 2 O14678 1 +Microbody membrane 0.6011513099409102 2.6908178786405004 0.0071277093971455 0.998499997765608 0.070424867847884 26 Q6IAN0,O14678,Q8TB36,O43808,Q9NP80,O14975,P51648,Q8WVX9,P28288,O15228,Q96K12,Q9NR77,Q15067 13 +Endoplasmic reticulum protein containing complex 0.4433011841404883 2.6762795385452853 0.0074444524887022 0.9988776396495528 0.0712316559182145 67 Q53GQ0,Q9UBV2,Q9UBU6,P51571,Q9H0U3,Q9UGP8,Q8TCT9,O15269,O15270,P14625,P67812,P46977,O43681,P13674,Q9NPA0,O43292,Q6NUQ1,Q15041,Q03519,Q6NTF9,Q03518,Q13438,Q9BUN8,Q9Y5M8,P04844,Q8TCJ2,P04439,Q9H490 28 +Endoplasmic reticulum golgi intermediate compartment 0.4573768431541971 2.607297604861522 0.009126000398812 0.9997596991240736 0.077099371809535 52 P80303,P24390,P49755,Q8N511,Q08379,Q13190,Q9BVK6,Q15363,O15533,P49257,O15258,Q96GC9,P51572,Q969H8,Q5VYK3,Q10472,O15498,P30533,Q9Y3B3,Q03519,Q03518,O15260,Q9Y282,Q15904,Q14789,Q12907,Q02818,Q8IUR0 28 +Triglyceride rich plasma lipoprotein particle 0.8226371061843469 2.6060121430660206 0.009160321403113 0.9997671472879868 0.077099371809535 2 Q9UHG3 1 +Phagocytic vesicle membrane 0.6106567635684066 2.561419175869233 0.0104245494065806 0.9999270438837012 0.0833812249756418 23 P13473,Q9Y487,P01889,P04439,Q03519,Q15907,Q03518,Q93050 8 +Secondary lysosome 0.8103850641773496 2.547622850853498 0.0108459657133381 0.9999504653279232 0.0843836897347604 2 P13473 1 +Autolysosome 0.8103850641773496 2.547622850853498 0.0108459657133381 0.9999504653279232 0.0843836897347604 2 P13473 1 +Specific granule membrane 0.725833014435692 2.530676383110699 0.0113842829991961 0.99996979998737 0.0856641236714847 14 Q4KMQ2,P30519,Q07065,O00264 4 +Vacuolar proton transporting v type atpase v0 domain 0.8915203197161067 2.52256324083776 0.0116502999694165 0.9999763534913964 0.0856641236714847 3 Q9Y487 1 +Proton transporting v type atpase v0 domain 0.8915203197161067 2.52256324083776 0.0116502999694165 0.9999763534913964 0.0856641236714847 3 Q9Y487 1 +Vesicle membrane 0.3248020564629116 2.5078958132747657 0.0121452471775906 0.9999850023862004 0.0876192832097614 273 P20020,Q5T9A4,P24390,Q9UIQ6,P10321,O00264,P35613,P04083,Q15907,Q8N511,Q14849,Q14457,O00461,Q4KMQ2,P07602,O14975,Q8WTV0,Q13277,P30519,Q9Y487,Q9UH99,P10253,Q14108,Q9Y287,Q15043,Q5T9L3,P42858,Q969Q5,P42892,O15127,Q96L92,P61586,Q9NZJ7,Q9UL01,P42785,Q9Y3B3,Q03519,Q03518,Q93050,O43731,O15260,Q9NQX7,O76024,Q96RL7,Q15904,Q15057,P55899,P13473,O15118,P01889,P04439,Q08431,Q8IV08,Q07065 54 +Mhc class i protein complex 0.885030639042895 2.494243671551907 0.0126225858394297 0.9999903346291108 0.0889451978917958 3 P01889,P04439 2 +Mhc protein complex 0.885030639042895 2.494243671551907 0.0126225858394297 0.9999903346291108 0.0889451978917958 3 P01889,P04439 2 +Nuclear membrane 0.3792919144622448 2.467835228132589 0.0135932874684816 0.9999960470505668 0.0943228878538154 110 Q86UE4,P67809,O00560,Q99720,Q8IXM6,O75844,Q15154,Q9P035,Q6ZRP7,Q5BJF2,Q7Z3B4,Q9H1E5,Q9H2V7,Q9UH99,P50402,Q8N201,Q96KC8,P62995,Q9BZF1,P43243,Q9NXE4,Q8NFQ8,Q99523,Q6NUM9,Q9BTX1,Q8N1F7,Q14739,Q9UBM7,O94901,O76062,Q14728 31 +Azurophil granule membrane 0.6027362213855688 2.446884284990626 0.0144097093658395 0.999998137730336 0.0950490300864684 22 Q9NQX7,P10253,Q92542,O15260,P07602,P13473,Q9NZJ7,P42785,Q9H0U3,Q8NF37,Q07065 11 +Platelet alpha granule membrane 0.7800466744457404 2.40138164607799 0.0163332917254912 0.9999996846392836 0.1045560716793771 2 Q6YHK3 1 +Neuronal ribonucleoprotein granule 0.862827853915856 2.396682001253628 0.0165442749010626 0.9999997405074418 0.1051660551403216 3 Q99729 1 +Endosome lumen 0.8528952855757961 2.3526998363748226 0.0186376721608991 0.9999999625968108 0.1168389240983265 3 Q9UIQ6 1 +Azurophil granule lumen 0.4377649801016554 2.33980372548687 0.0192938764898167 0.9999999796366928 0.1193070321717238 44 P17900,P10619,P61916,Q9BTY2,O00560,P16278,Q92820,P15586,Q9Y5Z4,P06280,Q9H7Z7,P07437,O00584,P08236 14 +Outer mitochondrial membrane protein complex 0.6594237033122436 2.333526167738486 0.0196205465673902 0.9999999849572044 0.120060090907802 16 Q9BUR5,Q8N4H5,Q16891,Q9NS69,Q5XKP0,Q9NX63,Q9Y512,Q13505,Q6UXV4,Q9NVH1 10 +Intrinsic component of vacuolar membrane 0.848326037622526 2.332396979203288 0.0196798168814769 0.9999999857615998 0.120060090907802 3 O15118 1 +Cis golgi network 0.656732505345539 2.316869925113403 0.0205108185050484 0.999999993413177 0.1242955601405935 16 O43731,O00461,P24390,Q9NPR9 4 +Parallel fiber to purkinje cell synapse 0.757876312718785 2.29301900051711 0.0218469110755425 0.9999999980953764 0.1279301408645435 2 O15020 1 +Dendritic spine membrane 0.757876312718779 2.293019000517079 0.0218469110755443 0.9999999980953764 0.1279301408645435 2 P20020 1 +Mitochondrial intermembrane space protein transporter complex 0.8348409687773409 2.2722218477979466 0.0230731143303388 0.9999999993910044 0.1322009156285248 3 Q9Y5J9,Q9Y5L4 2 +Oxidoreductase complex 0.4193509693943049 2.2689775994755 0.0232696881194323 0.9999999994928094 0.1322009156285248 62 P51970,P11177,Q96CU9,O43169,O95168,O43676,P31930,O14949,Q9P0J0,O75306,Q86Y39,P08574,O75438,P43304,P13674,P21912,Q9Y6M9,Q15118,P03886,Q9UDW1,P31350,P23378,O96000,P21953 24 +Basolateral plasma membrane 0.4507953958871344 2.2636624770896527 0.023594882004907 0.9999999996252747 0.1332158244873321 41 P20020,P55011,P78310,P05023,P11166,O14936,O94832,O75955,P57105,P53985,P35613,P30825,P23634,P04083,Q6P4Q7,Q14168,Q9Y6M7,Q15043 18 +Organelle membrane contact site 0.6096700752327372 2.2277648291497028 0.0258962013513055 0.9999999999561308 0.1409582771342861 18 A0FGR8,P51572,Q9NTJ5,Q96N66,Q96S66,Q5XKP0,O43865,Q14849,Q9Y320,P27824 10 +Cytochrome complex 0.6076545730505762 2.2143373690694794 0.0268055798064925 0.9999999999812308 0.1421504014118848 18 P14406,P08574,Q9UDW1,P13073,O14949,P00403 6 +Transporter complex 0.4178501095176739 2.2109952602764578 0.0270361652801949 0.999999999984868 0.1421504014118848 58 P51970,O14678,P51798,Q96CU9,O95168,O43676,Q9C0H2,O14949,Q9P0J0,O75306,Q4KMQ2,Q86Y39,P08574,Q9Y5J7,Q9Y5J9,Q9Y6M9,P03886,Q9UDW1,Q8IYU8,P05023,Q9Y5L4,Q9NUT2 22 +Late endosome 0.3963308585788563 2.2102043857868767 0.0270909807386043 0.9999999999856234 0.1421504014118848 71 P42858,P07602,Q5VYK3,Q9BUN8,P13473,Q9NZJ7,O15118,Q9BRK5,Q8IV08,Q96PU5,Q8TAF3,Q8IZ07,Q14849,Q14108,Q15043 15 +Er ubiquitin ligase complex 0.8037837399310204 2.175965470920963 0.0295578425472777 0.9999999999985696 0.1526595390652017 7 Q9UBV2,Q9UBU6,Q9BUN8,Q6NTF9 4 +Gamma secretase complex 0.7316219369895043 2.163077225130615 0.0305352404690077 0.9999999999994276 0.1553494811920416 2 Q92542 1 +Golgi lumen 0.8690628217817591 2.1592790411857408 0.0308285251410829 0.9999999999995652 0.1553494811920416 5 Q9BRK5,O00461 2 +Acrosomal membrane 0.8015985462218709 2.1222648147119005 0.0338155064129996 0.9999999999999736 0.1602695314140284 3 P35613 1 +Pore complex 0.7161676955675338 2.1218265019409697 0.0338523102656693 0.9999999999999746 0.1602695314140284 10 P12235,P21796,P45880 3 +Semaphorin receptor complex 0.7211201866977832 2.110616606861685 0.034805279082922 0.9999999999999896 0.1630824674555472 2 O14786 1 +Tim23 mitochondrial import inner membrane translocase complex 0.8207581403946662 2.041180490538688 0.0412328901556116 1.0 0.1847126481594237 6 O14925,O60830,Q99595 3 +Bcl 2 family protein complex 0.7071178529755032 2.0402476653093307 0.0413256644545474 1.0 0.1847126481594237 2 Q07820 1 +External side of plasma membrane 0.5554657254165025 2.010216848409344 0.0444082429593575 1.0 0.1950101103867439 20 P42892,O96005,P55899,P04083 4 +Microbody lumen 0.5240032794966873 1.973797057186231 0.0484048236082186 1.0 0.2037036326845867 24 Q2T9J0,A8MXV4,O75874,O14734,O15228,O15254,Q15067 7 +Organelle envelope lumen 0.439336597085918 1.9673396676726076 0.0491440647944521 1.0 0.2058615433094791 38 Q9Y5J9,P51970,Q9H4A6,Q9HB71,Q96AY3,Q16891,P36551,O14925,P05067,Q9Y5L4,Q9Y5J7,P07437,Q9NR28,Q8IYU8,O00584,Q9BYT8,O60313,O95831 18 +Respiratory chain complex iv 0.6686160530952063 1.9413989085690229 0.0522099105899585 1.0 0.2128197700729698 11 P14406,P13073,P00403 3 +Mitochondria associated endoplasmic reticulum membrane 0.6955763169669172 1.9387872592003277 0.0525272481573162 1.0 0.2131574489955378 9 P51572,Q96N66,Q96S66,O43865,Q9Y320,P27824 6 +Endosome 0.3090221306565008 1.935073512353778 0.0529812753747906 1.0 0.2140443525141544 237 Q9UIQ6,P10321,P35613,P04083,Q15907,Q8TAF3,Q8IZ07,Q14849,Q14457,O00461,O14773,P07602,Q9Y487,Q9UH99,Q9Y287,Q14108,Q15043,Q5T9L3,P42858,Q5VW38,Q969Q5,P42892,Q5VYK3,O15127,Q96L92,P05067,P61586,Q9NZJ7,Q9BRK5,Q96PU5,Q9NX40,Q93050,Q96RL7,Q9BUN8,Q15057,P55899,P13473,O15118,P01889,P04439,Q92544,Q8IV08,Q13510 43 +Cell body membrane 0.7580974613364372 1.922661366752505 0.0545225916697631 1.0 0.2154827644687823 3 P20020,P55011 2 +Dendrite membrane 0.7580974613364273 1.922661366752459 0.0545225916697689 1.0 0.2154827644687823 3 P20020,Q14168 2 +Microtubule organizing center attachment site 0.7530689648734634 1.8993529942733245 0.0575180794522336 1.0 0.2240779162049921 3 O94901 1 +Neuron spine 0.4268720097176442 1.895674232166151 0.0580031346761742 1.0 0.2240779162049921 39 P20020,P51116,P46934,Q06787,P05067,P61586,Q9UQB8,P51114,Q14168 9 +Secretory vesicle 0.3010835833217919 1.8954914931236728 0.0580273176927921 1.0 0.2240779162049921 268 P20020,O75874,Q5T9A4,O00560,P10321,P45880,O00264,P06865,P35613,P06280,Q9UQB8,P50897,Q15907,P08236,Q4KMQ2,P07602,O14975,Q08380,P16278,P30519,Q13277,Q9Y487,Q92820,Q9Y5Z4,P20618,P10253,P07437,Q7L576,P17900,Q969Q5,P42892,Q9BTY2,P05067,P15586,P42785,P61586,Q9NZJ7,Q99519,Q9NUQ9,Q9H7Z7,Q93050,O00584,Q8NBX0,Q9NQX7,O15260,P10619,O76024,Q96RL7,P13473,P01889,Q08431,Q9NTK5,Q8NF37,Q13510,Q07065 55 +Basal part of cell 0.3956715276466431 1.8931490898802743 0.0583380454854478 1.0 0.2240779162049921 51 P20020,O94832,P53985,P35613,P30825,P04083,Q9Y6M7,P11166,O75955,Q14168,P23634,Q15043,P55011,P42785,Q6P4Q7,P78310,P05023,O14936,P57105 19 +Secretory granule 0.3060757231309714 1.8907697399594423 0.0586550882373491 1.0 0.2240779162049921 244 O75874,Q5T9A4,O00560,P10321,P45880,O00264,P06865,P35613,P06280,Q9UQB8,P08236,Q4KMQ2,P07602,O14975,Q08380,P16278,P30519,Q13277,Q9Y487,Q92820,Q9Y5Z4,P20618,P10253,P07437,Q7L576,P17900,Q969Q5,P42892,Q9BTY2,P05067,P15586,P42785,P61586,Q9NZJ7,Q99519,Q9NUQ9,Q9H7Z7,Q93050,O00584,Q8NBX0,Q9NQX7,O15260,P10619,O76024,Q96RL7,P13473,P01889,Q08431,Q9NTK5,Q8NF37,Q13510,Q07065 52 +Intrinsic component of golgi membrane 0.7423312883435771 1.883372393275809 0.0596499189055568 1.0 0.2250103002786668 7 Q9Y282,Q6ZRP7,L0R6Q1,Q8TB61,O43505,O15258 6 +Pole plasm 0.8011492853632353 1.864866222357382 0.062200158074972 1.0 0.2311798107355185 5 Q9Y2W6 1 +External encapsulating structure 0.4385455489746693 1.8640891218387747 0.0623091899122134 1.0 0.2311798107355185 36 Q32P28,P07602,Q53GQ0,Q08380,P14625,Q92896,Q9NZJ7,P04083 8 +Nls dependent protein nuclear import complex 0.7342801715111575 1.8444657165704323 0.0651152977038884 1.0 0.2367592224513384 7 P52294 1 +Atpase dependent transmembrane transport complex 0.8140634781483469 1.8390739771165177 0.0659043059649437 1.0 0.23867336303639 4 O14678,Q9NUT2 2 +Integral component of synaptic vesicle membrane 0.7391304347825919 1.8345026580491308 0.0665794135955111 1.0 0.2393627456462889 3 P20020,O76024 2 +Intrinsic component of peroxisomal membrane 0.8096906012842927 1.82038787619859 0.0686999574104465 1.0 0.2458592964019524 4 O14975,Q96K12,O43808 3 +Hrd1p ubiquitin ligase erad l complex 0.7901001895158116 1.8162347521548952 0.0693343692919259 1.0 0.2471566340641595 5 Q9UBV2,Q9BUN8 2 +Micos complex 0.7894890510948904 1.8135393171262115 0.0697486802334801 1.0 0.2476623059852868 5 Q9BUR5,Q5XKP0,Q6UXV4,Q16891 4 +Nadh dehydrogenase complex 0.503117556353951 1.8110440452200949 0.0701340339488922 1.0 0.2480616220215684 24 O75306,P51970,Q9Y6M9,O96000,Q86Y39,P03886,Q96CU9,O95168,O43676,Q9P0J0 10 +Mcrd mediated mrna stability complex 0.7877719256464822 1.8059628340639209 0.0709241451316553 1.0 0.2498839066847857 5 Q14103,O60506 2 +Zymogen granule membrane 0.7318354245695936 1.800424480194645 0.0717936382701367 1.0 0.2507977021726432 3 Q13277,Q15363 2 +Mmxd complex 0.7318115321179459 1.800312717096359 0.0718112739927734 1.0 0.2507977021726432 3 P05141 1 +Paranodal junction 0.6595682613769029 1.7978647410890591 0.0721984447856414 1.0 0.2507977021726432 2 O15020 1 +Postsynaptic density membrane 0.6789174028357334 1.7849378594255754 0.0742713968560366 1.0 0.2522124054594782 8 Q99720,P57105 2 +Golgi medial cisterna 0.8006421482778582 1.7816341196012575 0.0748089166388177 1.0 0.2522124054594782 4 Q96L58,P04439,Q16706 3 +Apical plasma membrane 0.3935928717367424 1.7814277052477443 0.0748426055260971 1.0 0.2522124054594782 43 P20020,Q86UE4,P36551,P53985,P30825,P04083,Q9Y6M7,O15020,P08183,Q99797,P11166,Q13277,O75955,P23634,Q15043,P55011,Q9Y4G8,Q16625,O43865,P05023 20 +Mib complex 0.6529417037616226 1.7799829866839851 0.0750787450628172 1.0 0.2522124054594782 10 Q9BUR5,Q16891,Q5XKP0,Q9Y512,Q13505,Q6UXV4,Q9NVH1 7 +Mpp7 dlg1 lin7 complex 0.6560676779463297 1.7798248356847848 0.0751046317790631 1.0 0.2522124054594782 2 Q5T2T1 1 +Rough endoplasmic reticulum 0.4334454203926118 1.774380461699255 0.0760002394581713 1.0 0.2522124054594782 35 Q99442,P51571,Q9UQB8,Q9UGP8,Q5VV42,Q8TCT9,Q5BJF2,Q9H9S5,P05067,Q15041,P62266,P27824,P36578,Q9HD47,Q96A33,Q9Y5M8,P04844,Q07065,O60568 19 +Neurofilament 0.7987300067556251 1.7734296765773137 0.0761575351180756 1.0 0.2522124054594782 4 P07197,Q16352 2 +Messenger ribonucleoprotein complex 0.761099314614732 1.7716846512928002 0.0764469189061809 1.0 0.2522124054594782 6 P67809,Q99729,Q06787,P51991 4 +Dendritic growth cone 0.7255249300361605 1.7708719123757968 0.0765820040470848 1.0 0.2522124054594782 3 Q7L576 1 +Tim22 mitochondrial import inner membrane insertion complex 0.7227896119054241 1.758041520042171 0.0787404449318813 1.0 0.2542593086435487 3 Q9Y5J7,Q9Y584 2 +Paranode region of axon 0.6505250875145907 1.751210940807653 0.0799095815715049 1.0 0.2557669353820352 2 Q8IXJ6 1 +Risc loading complex 0.7197687405681434 1.743857454198406 0.0811839490478125 1.0 0.2580287051904252 3 O75569 1 +Derlin 1 retrotranslocation complex 0.7826478191268003 1.7042278025279725 0.0883385369916118 1.0 0.2740605123732941 4 Q8TCT9,Q9BUN8 2 +Specific granule 0.4293897355359081 1.6983902364032206 0.0894341336385275 1.0 0.276515739719121 34 Q4KMQ2,O14975,Q13277,P30519,Q92820,O00264,Q99519,Q07065 8 +Nuclear stress granule 0.705948494622876 1.6787824222451435 0.0931944555787647 1.0 0.2842743628224736 3 P31483 1 +Mitotic spindle microtubule 0.7398561623778586 1.6743033972272665 0.0940709871897231 1.0 0.2857196518464507 6 O94927,Q9H6D7,Q00839 3 +Haus complex 0.7730232895855258 1.6626518093920968 0.0963821538548717 1.0 0.2910677005118883 4 O94927,Q9H6D7 2 +Glial cell projection 0.7513228302133887 1.6441268268768088 0.1001500076167156 1.0 0.2984798587658837 5 Q06787 1 +Postsynaptic cytoskeleton 0.6292298716452784 1.640728864019542 0.1008537104967701 1.0 0.2995948458874643 2 O15020 1 +Copii coated er to golgi transport vesicle 0.4457284976490439 1.6312451345881789 0.1028386051430154 1.0 0.3039522183267166 29 Q13190,Q9Y282,Q15363,Q5VYK3,P10321,P05067,Q12907,P49257,P01889,Q9Y3B3,O95487,P04439,P49755,Q08379 14 +Copi coated vesicle membrane 0.5623981936815353 1.630531039630818 0.1029893105001416 1.0 0.3039522183267166 15 Q8N511,P24390 2 +Lumenal side of membrane 0.6145336889904915 1.5677264494414185 0.1169449862425109 1.0 0.3342861399196303 10 Q8TCT9,P51572,P10619,P10321,P01889,P04439 6 +Dendrite terminus 0.7478466586439804 1.5533802311071685 0.120332322909842 1.0 0.3418082011257951 4 Q7L576,Q9Y366 2 +Ficolin 1 rich granule membrane 0.4974370579800381 1.5517600428308738 0.1207196499603648 1.0 0.3418082011257951 19 Q5T9A4,P13473,P42785,P10253,Q93050 5 +Copi coated vesicle 0.5225882489127147 1.5389511067965604 0.1238162330221643 1.0 0.3473715156179482 17 Q8N511,P24390 2 +U2af complex 0.6692584816219525 1.504728173145885 0.1323939767614232 1.0 0.3612574852606838 3 P26368 1 +Protein lipid complex 0.668830084981253 1.5026864597850398 0.1329199159719452 1.0 0.3612574852606838 3 Q9UHG3 1 +Coated vesicle 0.3218799321500922 1.497688036861812 0.1342143214591606 1.0 0.3612574852606838 90 O43731,Q5VW38,P42892,P24390,Q5VYK3,Q9Y282,P05067,Q8N511,Q14108 9 +Golgi associated vesicle membrane 0.4744881521399511 1.494113567137859 0.1351459384877689 1.0 0.361806916754233 22 Q8N511,P24390,O43731 3 +Transport vesicle 0.3216221735388337 1.4934122061217985 0.1353293197980629 1.0 0.361806916754233 91 P20020,P24390,P11279,P10321,Q8TBA6,P50897,Q15907,O00461,Q13190,Q13277,O95249,P05067,Q9Y3B3,Q99523,O43731,Q92542,O15260,O76024,P01889,P04439,O95487 21 +Golgi cisterna membrane 0.5019037171340341 1.48672806782242 0.137086646463362 1.0 0.363508137497332 18 P51572,Q9H4A6,Q10713,Q15363,Q10472,Q8NBN3,Q96L58,O60512,Q99523,Q10471,P0CG08,O00461 12 +Nuclear envelope lumen 0.713503485643552 1.4744590714382406 0.1403580297744486 1.0 0.370529503925835 5 P07437,P05067 2 +Origin recognition complex 0.7131040275244274 1.4726594456830906 0.1408428869526534 1.0 0.370529503925835 5 Q9Y619 1 +Postsynaptic endosome 0.5956826137689618 1.465199424412546 0.1428665166015599 1.0 0.3715999393791109 2 Q86Y82 1 +Postsynaptic recycling endosome 0.5956826137689618 1.465199424412546 0.1428665166015599 1.0 0.3715999393791109 2 Q86Y82 1 +Proteasome core complex beta subunit complex 0.6564985023590377 1.462920676686663 0.143489085502825 1.0 0.3715999393791109 7 P49721,P28072 2 +Golgi associated vesicle 0.4078072830670172 1.458019667143015 0.1448351221168484 1.0 0.3728762289902921 33 Q8N511,Q9Y287,P24390,O43731 4 +Mitochondrial permeability transition pore complex 0.7090499911636691 1.4543880126489306 0.1458387615027869 1.0 0.3728762289902921 5 P21796 1 +Proton transporting two sector atpase complex proton transporting domain 0.6032034882377812 1.4424903081078833 0.1491641037770521 1.0 0.3766393620370566 9 P24539,Q9Y487,O75964 3 +Dystrophin associated glycoprotein complex 0.58897316219371 1.4299263180771915 0.1527381675700279 1.0 0.3814258085746026 2 Q13425 1 +Glycoprotein complex 0.58897316219371 1.4299263180771915 0.1527381675700279 1.0 0.3814258085746026 2 Q13425 1 +Lumenal side of endoplasmic reticulum membrane 0.6089486148601473 1.4161470642773415 0.1567324508440739 1.0 0.3892617426701181 8 Q8TCT9,P51572,P10321,P01889,P04439 5 +Blood microparticle 0.5033813088161948 1.4075511113908483 0.1592640325308085 1.0 0.3923333484295527 17 P38435,O00560,P04062 3 +Axolemma 0.6457543040560351 1.3924694845704289 0.1637802760322326 1.0 0.4012837490924514 3 O94832,Q9Y2J2 2 +Neuron projection membrane 0.5935139749582412 1.38961672221947 0.1646452951052799 1.0 0.4023187452975791 9 Q01082,P20020,O94832,Q9Y2J2,Q14168,P23634 6 +Crd mediated mrna stability complex 0.6755080556732989 1.3758943614451988 0.1688543411706451 1.0 0.4114975767402585 6 P67809,Q00839,O60506 3 +Neuron projection terminus 0.5448942792640786 1.3728365995966627 0.1698031499315795 1.0 0.4127033777748817 13 Q9UQB8,Q06787,Q13641 3 +Late endosome membrane 0.3880157010069154 1.3612660802142875 0.1734296181840842 1.0 0.4181631907939855 36 O15118,Q8IV08,Q14849,Q14108,Q15043 5 +Intrinsic component of synaptic vesicle membrane 0.6309165166214482 1.3357986065188274 0.1816151085793498 1.0 0.4310359059926644 7 P20020,O76024 2 +Membrane microdomain 0.3389185928134556 1.3278694990497968 0.1842212224684476 1.0 0.4338266612016033 67 P20020,P21796,O00560,P30154,P35613,Q9UBN7,P50897,P49327,O14773,Q6IAA8,P11166,Q8WTV0,O75955,P46108,P07437,P09601,P23634,Q9BTU6,P05067,P78310,P05023,Q9HD47,P13473,P05141,O15118 25 +Nucleocytoplasmic transport complex 0.5809600931501786 1.3209944285558366 0.1865032219319495 1.0 0.4380657073285327 9 P52294 1 +Sarcoplasmic reticulum lumen 0.6278980020190086 1.3069551778275543 0.1912279346204131 1.0 0.445708186076809 3 P14625 1 +Chromatoid body 0.5641773628938289 1.2992871193450584 0.1938454131098776 1.0 0.4479671171193673 2 Q08J23 1 +Collagen containing extracellular matrix 0.3940342224189098 1.2978015076428524 0.1943555514430759 1.0 0.4479671171193673 32 Q32P28,P07602,Q08380,P14625,Q9NZJ7,P04083 6 +Cytoplasmic stress granule 0.3447573713565715 1.2817598550553064 0.1999269008339039 1.0 0.4509517440645625 46 Q9H2U1,P61978,P31483,P67809,Q9HCE1,P11940,P54646,Q06787,Q01085,Q14157,Q9BWF3 11 +Nucleoid 0.3866087543802456 1.253443529758547 0.2100443381022547 1.0 0.4669020928461502 33 Q04837,P21796,P06576,P36776,P05141,P45880,O76031,Q96AG4,Q9H5Q4,Q9Y2S7,O00411,P40939,Q9NVI7,Q96RR1 14 +Dendritic tree 0.3009813047831765 1.2506957494218465 0.2110455018491022 1.0 0.4669020928461502 122 P20020,Q13641,Q9UBN7,Q9UQB8,P50897,P21964,Q14457,P98179,P33176,Q99729,Q13277,Q7L576,Q14168,P42858,Q9H2U1,P23246,Q9BTU6,P54646,Q06787,P05067,P61586,P51114,P42345,Q00839,P51116,O76024,P46934,Q9Y366,P52294,O60313 30 +Postsynaptic specialization membrane 0.535493706534759 1.2457787240676803 0.2128456425964526 1.0 0.4684665596130157 12 Q99720,P57105 2 +Respiratory chain complex iii 0.5730762230753845 1.2249030081131271 0.2206117669130955 1.0 0.4820579233750093 8 Q9UDW1,O14949 2 +Golgi cisterna 0.4277970018753638 1.2093200850845112 0.2265398973786951 1.0 0.491467223668816 24 P51572,Q9H4A6,Q10713,Q16706,Q15363,Q10472,Q8TBA6,O95249,Q8NBN3,Q96L58,O60512,P04439,Q99523,Q10471,P0CG08,O00461 16 +Phagophore assembly site 0.5390232009828378 1.2027729203462911 0.2290642066449504 1.0 0.495760390095857 11 Q9H6U6,Q96GC9,Q7Z3C6,Q14457 4 +Ciliary transition zone 0.5577558503593475 1.1940005356560413 0.2324777585199777 1.0 0.5019531650704507 9 P41208,Q15154,A6NIH7 3 +Dendrite cytoplasm 0.52548419836722 1.1862941715917708 0.2355061475520075 1.0 0.507178816179846 12 P23246,P33176,Q00839,Q9UQB8 4 +Cyclin cdk positive transcription elongation factor complex 0.602448072706505 1.185008959362825 0.2360139045589382 1.0 0.507178816179846 3 Q9NYV4 1 +Mhc class i peptide loading complex 0.6319268898941515 1.1723228714516063 0.2410674524051395 1.0 0.515600739379463 6 Q03518,Q03519 2 +Tertiary granule 0.3485603907134084 1.164940976747876 0.2440428852760807 1.0 0.5207393960468484 41 Q5T9A4,O75874,Q4KMQ2,P61586,Q92820,P42785,P13473,P10253,Q13510,Q93050 10 +Intrinsic component of nuclear inner membrane 0.5942919854001008 1.153424699113507 0.2487361085039023 1.0 0.527042243892884 7 O94901,Q14739,Q9UH99 3 +Snare complex 0.5072921346164235 1.1428006767399803 0.2531213577736129 1.0 0.5301551018806777 13 Q86Y82,Q13190,Q9P2W9,Q13277,O95249,O15498,Q9UNK0,P51809 8 +Nuclear outer membrane 0.5334607111734532 1.1133222282284696 0.265570063136751 1.0 0.543700872502943 10 P50402,Q99720,Q6NUM9,Q9NXE4 4 +Pigment granule 0.3269176902753733 1.0851708543398393 0.2778459903334234 1.0 0.5587654982590307 59 P57088,O00560,P11279,P35613,P50995,P49755,P49327,P07900,O14773,P11166,Q13277,P14625,O75955,Q92820,O43852,P55209,Q93050,P27824,Q92542,P05023,P04843 21 +Side of membrane 0.3132382053497048 1.0710458857758058 0.2841487981504125 1.0 0.5698609531426134 71 Q8TCT9,P20020,P08183,P17900,P10619,P42892,O96005,P61586,P55899,P01889,P04439,P04083 12 +Cell surface 0.2955717423245592 1.0698945399199045 0.2846667810677876 1.0 0.5698609531426134 80 Q99623,Q13641,P11279,O96005,P10321,P04083,O75592,P49327,Q8TCT9,P08183,Q4KMQ2,Q8WTV0,P06576,O75955,O43847,Q6YHK3,P42892,P05067,Q99523,Q00839,Q07021,P55899,Q12907,P01889,P04439,Q08431 26 +Golgi apparatus subcompartment 0.2946816827862841 1.068128825248047 0.2854624048811041 1.0 0.5698609531426134 90 Q8TBA6,O60512,Q14457,P04062,O00461,Q10713,Q16706,P22059,Q5T9L3,Q5VYK3,O15127,Q9BTU6,Q10472,P05067,Q9NXE4,Q96L58,Q8NBN3,Q9NPR9,Q4J6C6,P04439,O60568 21 +Endosome membrane 0.2865079813264945 1.0516260720958148 0.2929711410746314 1.0 0.5766133262492269 135 P10321,P04083,Q15907,Q14849,Q14457,O00461,Q9Y487,Q9UH99,Q9Y287,Q14108,Q15043,P42892,O15127,Q96L92,Q93050,Q96RL7,Q15057,P55899,P13473,O15118,P01889,P04439,Q8IV08 23 +Zymogen granule 0.6328845715257402 1.0500425789426648 0.2936985369124225 1.0 0.5766133262492269 4 Q13277,Q15363 2 +Proton transporting two sector atpase complex 0.4165125554332625 1.0446471282303225 0.2961860893781645 1.0 0.5775150022806066 22 Q8N511,P24539,Q9Y487,O75964 4 +Excitatory synapse 0.6042798800941355 1.0435381388286424 0.296699126584206 1.0 0.5775150022806066 6 Q7L576,Q9UQB8,O15020 3 +Mitochondrial alpha ketoglutarate dehydrogenase complex 0.6230413913576726 1.007190075050788 0.3138434416204307 1.0 0.6056978522993026 4 O14874,P21953 2 +Calcium and calmodulin dependent protein kinase complex 0.5075845974329138 1.0017887194662571 0.3164456465616041 1.0 0.6092791662964547 2 Q13555 1 +Beta catenin destruction complex 0.6209279507785543 0.9980083382583746 0.3182753153607793 1.0 0.6092791662964547 4 P48729 1 +Nuclear pore outer ring 0.5942499289636657 0.9970437515490408 0.318743273699043 1.0 0.6092791662964547 6 Q9BW27,Q8NFH4,P52948,Q12769 4 +Autophagosome 0.386286814791431 0.9964110288300456 0.3190504765204758 1.0 0.6092791662964547 27 P42858,Q969Q5,P11279,P13473,P04844,Q8TBX8,Q9Y6I9,Q7Z3C6,Q96GC9,Q14457 10 +Presynaptic cytoskeleton 0.5029171528588177 0.977477858506182 0.3283326341197938 1.0 0.6201634903835128 2 P07196 1 +Oligosaccharyltransferase complex 0.5263411518118966 0.9764458556235388 0.3288435669580343 1.0 0.6201634903835128 8 Q9H0U3,Q8TCJ2,P46977,P04844 4 +Lateral plasma membrane 0.4103284509013473 0.96590858610756 0.3340899255670868 1.0 0.6287530897318466 21 P53985,Q8TAA9,P55011,P04083 4 +Presynaptic active zone membrane 0.5993733449197862 0.9595525261296808 0.3372804718395634 1.0 0.6293453486933475 5 P20020,Q13277,P27824 3 +Intermediate filament 0.4089737855828887 0.9556460888950136 0.3392510680525196 1.0 0.6293453486933475 21 Q16352,O14786,P07197,P48729,P08670 5 +Extrinsic component of mitochondrial inner membrane 0.6050802154194358 0.9294216909035238 0.352670590958156 1.0 0.6476314488504319 4 Q8NI60,Q96BW9 2 +Lipid droplet 0.3502381135571252 0.9017640475076564 0.3671822219606944 1.0 0.6587462976906089 33 P51572,Q6UX53,Q96RL7,P41247,Q8NF37,Q99720,Q07065,Q8NBX0 8 +Cytoplasmic ubiquitin ligase complex 0.4949526726063996 0.8986877087057318 0.3688190257741452 1.0 0.6587462976906089 10 Q9UBV2,Q9UBU6,Q9BUN8,Q6NTF9 4 +Intrinsic component of presynaptic membrane 0.5847495002248266 0.8945213362924657 0.371043019161267 1.0 0.6587462976906089 5 P20020,Q92542,P27824 3 +Dynactin complex 0.5807627511789955 0.8768875800102867 0.3805477028496624 1.0 0.665354380885642 5 Q9UJW0 1 +Neuron to neuron synapse 0.3008530115839101 0.87604974310195 0.3810029923334044 1.0 0.665354380885642 70 P55795,P51116,P51991,Q06787,P57105,Q9UQB8,P51114,P52294,Q99720,Q14168 10 +Caveola 0.4354903109047806 0.8739771419155921 0.3821307020463675 1.0 0.6654344983910884 16 Q9HD47,P09601 2 +Apical part of cell 0.3077034409548676 0.8382424651615177 0.4018945418078401 1.0 0.6777776224551515 56 P20020,Q86UE4,P36551,P53985,P30825,P04083,Q9Y6M7,O15020,P08183,Q15154,Q99797,P11166,Q13277,O75955,Q15043,P55011,P05067,Q9Y4G8,P41208,Q16625,O43865,P05023 22 +Chromocenter 0.5487573787240756 0.7891353801163801 0.4300328853024586 1.0 0.7094371919055079 6 Q06787 1 +Sex chromatin 0.5152089751786098 0.7737431258621912 0.4390827115927007 1.0 0.7207994750814729 3 Q15022 1 +Dendritic shaft 0.5403357203349994 0.7514280072921274 0.4523951125440082 1.0 0.7304407905751881 6 Q9UQB8,P05067 2 +Nuclear pore 0.2986710667758995 0.7401096599649469 0.4592334577129762 1.0 0.7378291068156396 46 Q8TD16,P41208,Q12769,Q7Z3B4,Q99567,Q8NFH4,Q9C0E2,P52294,Q5SRE5,Q9BTX1,Q8N1F7 11 +Proton transporting v type atpase complex 0.4470600662251816 0.7269473113343247 0.4672582330281636 1.0 0.742800609890077 12 Q8N511,Q9Y487 2 +Mitochondrial large ribosomal subunit 0.3365153987646041 0.7246501218063189 0.4686667017286701 1.0 0.742800609890077 31 Q9NVS2,Q14197,Q5T653,Q9BYC9,Q9NQ50,Q9H2W6,Q9NP92,Q567V2,Q7Z7H8,P09001,Q9BRJ2 11 +Tertiary granule membrane 0.4762052245829458 0.716364564692707 0.4737662693106346 1.0 0.7489626761797684 8 Q4KMQ2 1 +Filopodium tip 0.5247453468375707 0.6825267235297713 0.4949059507611675 1.0 0.7703245021265432 6 Q7L576,Q06787 2 +Intrinsic component of presynaptic active zone membrane 0.5405680769446775 0.6581022087188454 0.5104724567016705 1.0 0.7791633778619 4 P20020,P27824 2 +Integral component of presynaptic active zone membrane 0.5405680769446775 0.6581022087188454 0.5104724567016705 1.0 0.7791633778619 4 P20020,P27824 2 +Stereocilium membrane 0.488473883863451 0.6533416791768352 0.5135360281813015 1.0 0.7791633778619 3 Q9HBM0,Q12965 2 +Nucleotide excision repair complex 0.5284364773411779 0.651008801802189 0.5150408051223887 1.0 0.7791633778619 5 P41208 1 +Apicolateral plasma membrane 0.4630378249243745 0.6503094546698396 0.5154923511072667 1.0 0.7791633778619 8 Q16625,P46934 2 +Nuclear pore nuclear basket 0.4606014553831171 0.6382298828584813 0.5233240474562191 1.0 0.7803371357206492 8 P41208,P52948,P49792 3 +Anaphase promoting complex 0.446599191423177 0.6377159760242198 0.5236585839269483 1.0 0.7803371357206492 10 Q9UJX4,Q9UJX2,Q9H1A4,Q13042,P30260 5 +Mitochondrial proton transporting atp synthase complex coupling factor f o 0.5236857578825816 0.6311770674877109 0.5279247546961368 1.0 0.7830020672610889 5 O75964 1 +Platelet alpha granule 0.3869665636077219 0.6171337648536206 0.537146499315065 1.0 0.7913552153604442 17 O00186,P05067,Q9UHQ9,Q9Y6I9,O43707,Q9NUQ9,Q6YHK3,Q6UXV4,Q8NBX0,Q9NTK5 10 +Postsynaptic cytosol 0.5182788453684826 0.6087810340265801 0.5426695864986724 1.0 0.794364167223549 5 Q9UQB8 1 +Proton transporting atp synthase complex coupling factor f o 0.5063652058503528 0.6031139079648667 0.5464329148043383 1.0 0.7985651439825459 6 O75964 1 +Anchored component of synaptic vesicle membrane 0.5239346176298942 0.5913405418462749 0.5542922704530562 1.0 0.8023115825506817 4 P51149,P61020,Q15286 3 +Laminin complex 0.4238623103850701 0.5816823169901822 0.5607806845398209 1.0 0.8075345037978741 2 P11047 1 +Carboxy terminal domain protein kinase complex 0.4754557864856781 0.5806829833742736 0.5614541324535274 1.0 0.8075345037978741 7 Q9NYV4,P18074 2 +Endoplasmic reticulum tubular network membrane 0.518015828308486 0.5680206144694986 0.5700209703637522 1.0 0.8172698139757899 4 Q9NQC3 1 +Sperm connecting piece 0.4197782963827348 0.5625321852303633 0.5737534813382226 1.0 0.8203769070759911 2 P10644 1 +Gpi anchor transamidase complex 0.5068684049164418 0.5621804447781494 0.5739930834987133 1.0 0.8203769070759911 5 O43292 1 +Equatorial microtubule organizing center 0.4171528588098178 0.5503174416946157 0.5821016632292555 1.0 0.8241906727031048 2 Q96CW5 1 +Distal axon 0.284149649365747 0.5485255441744981 0.5833310945123471 1.0 0.8246469127709541 61 Q13641,P51116,Q13277,Q06787,Q9UPT5,P05067,P51114,Q7L576,Q99720 9 +Recycling endosome 0.2910549383480322 0.5416691815072695 0.5880464239360568 1.0 0.829345032668926 41 O14773,O15127,P05067,P01889,P04439,Q15907 6 +Chromosome passenger complex 0.511086491554372 0.5410412533688949 0.5884791485934624 1.0 0.829345032668926 4 O14965 1 +Golgi stack 0.3081732299185298 0.5243898285153983 0.6000074296505542 1.0 0.8403802057817469 34 P51572,Q9H4A6,Q10713,Q16706,Q15363,Q10472,Q8TBA6,O95249,Q8NBN3,Q96L58,O60512,P04439,Q99523,Q10471,P0CG08,O00461 16 +Schaffer collateral ca1 synapse 0.3847370160976952 0.504106134869652 0.6141867960758796 1.0 0.8446229918804455 15 Q9UQB8,Q13277,Q16352 3 +Smooth endoplasmic reticulum 0.4129053656819009 0.500220240847516 0.6169200076596646 1.0 0.8471001313634972 11 P27635,P05067,O00264,Q14BN4,P27824 5 +Coated vesicle membrane 0.2795398803333254 0.4931543174858702 0.6219035535130422 1.0 0.852655098255438 60 O43731,P24390,P10321,P01889,P04439,Q8N511,Q14108 7 +Site of polarized growth 0.2772153981316993 0.4721704560347853 0.6368051257243343 1.0 0.8665506875500297 55 P51116,P78310,Q9UKA9,Q13277,Q9BTU6,Q9UPT5,P05067,Q06787,P51114,Q7L576,Q99720,P07900 12 +Ribonucleoprotein granule 0.2572943414220252 0.4687151046883103 0.6392732888481498 1.0 0.8673125665118928 113 P61978,P67809,P11940,Q9BWF3,Q16352,P51991,Q99729,Q01085,Q9Y2W6,P07437,Q16637,Q9H2U1,P31483,P54646,Q9H6S0,Q06787,P51114,Q00839,P51116,Q9HCE1,Q08211,Q14157,Q07065 23 +Brisc complex 0.4912434325744365 0.4659223004806195 0.6412711180497241 1.0 0.8674336998619037 4 P34897,Q9NXR7,Q15018 3 +Spindle pole centrosome 0.4478755511096398 0.4598794805360971 0.6456027294293967 1.0 0.8719953656037467 7 P50402,O14965,Q96GD4 3 +Centriole 0.2974751683373254 0.4443004715024114 0.6568253603973304 1.0 0.8822211493352548 35 Q15154,P42858,Q9P2S5,P27695,O14965,O95684,Q9Y5Y2,Q9Y366,O95613,O15078,P53350,P41208,Q9Y496 13 +Sarcolemma 0.3301317393859009 0.4439817265562998 0.6570557954895131 1.0 0.8822211493352548 24 Q92542,P05023,P11166,P11279,O75955,Q9NXE4,P35613,Q14BN4,P04083,P23634 10 +Clathrin coated vesicle 0.2729590729774949 0.440731560813966 0.6594073452560281 1.0 0.8840726797016659 48 Q14108,Q5VW38 2 +Ciliary basal body 0.3288349440629722 0.4346503767899639 0.6638162227802302 1.0 0.8886729698191889 24 Q15154,A0AVF1,Q9P2S5,Q9Y366,Q9UPT5,P48729,P41208 7 +Trans golgi network 0.2744319316273623 0.4301810657552196 0.6670639341634719 1.0 0.889320722224537 62 Q5VYK3,O15127,Q9NPR9,P05067,Q4J6C6,P04062,P22059,O60568,Q14457 9 +Apical junction complex 0.2991305432389063 0.4275880325938165 0.6689510803538439 1.0 0.889320722224537 33 P78310,Q86UE4,P61586,Q92974,Q9Y4G8,Q16625,Q9NR77 7 +Mitochondrial pyruvate dehydrogenase complex 0.4626218692716276 0.4248743939268054 0.6709282419690461 1.0 0.889320722224537 6 Q15118 1 +Presynaptic active zone 0.3628637510543125 0.4204858518658962 0.6741305628187448 1.0 0.8919718800614833 16 Q99623,P20020,Q07021,Q13277,O75955,P05067,P27824 7 +Proton transporting atp synthase complex 0.4025589447405152 0.4177585322901557 0.676123672299596 1.0 0.8924714399977819 10 O75964 1 +Multivesicular body 0.4024578481016627 0.4172825487640066 0.6764717515494738 1.0 0.8924714399977819 10 P11279,Q96PU5,Q5VYK3 3 +Protein phosphatase type 2a complex 0.4565425109357948 0.4016116058400349 0.6879698871923825 1.0 0.903706109043173 6 P30154,Q16537,Q14738 3 +Epsilon dna polymerase complex 0.4702028430244999 0.390276738001185 0.6963319225726086 1.0 0.9133704438939412 4 Q07864 1 +Autophagosome membrane 0.3902684163652575 0.3884309173773544 0.6976971681006947 1.0 0.913842544385492 11 P11279,P13473,P04844,Q9Y6I9,Q96GC9 5 +Intraciliary transport particle b 0.4205080135892237 0.3739709642033511 0.7084259186050152 1.0 0.9186293295463036 3 A0AVF1 1 +Filopodium 0.2911398859050074 0.3722990753097338 0.7096701870177267 1.0 0.918931908830646 34 P51116,Q06787,Q9UQB8,P51114 4 +Platelet alpha granule lumen 0.3762953119997834 0.3515504541774551 0.725175427845975 1.0 0.9267372580265236 12 P05067,Q9Y6I9,Q9NUQ9,Q6UXV4,Q8NBX0,Q9NTK5 6 +Pronucleus 0.4418696859520134 0.3472985039694481 0.728367074585559 1.0 0.9267372580265236 6 P11166,O14965 2 +Presynaptic membrane 0.325447508604774 0.3441857419913342 0.7307066042522286 1.0 0.9267372580265236 20 P20020,Q92542,O14936,Q9BTU6,Q13277,Q06787,Q96CX2,P27824 8 +Transcription factor tfiih holo complex 0.4559252772913079 0.3416745606627064 0.7325958188055448 1.0 0.9267372580265236 4 Q96T76,P18074,P19447 3 +Mismatch repair complex 0.4111467756054972 0.3397440133503705 0.7340493132883354 1.0 0.9267372580265236 3 P52701,P20585 2 +Acrosomal vesicle 0.3200849972056505 0.3372433051505926 0.7359334946009444 1.0 0.9278273877839922 22 Q9Y487,P45880 2 +Exocyst 0.4171402573233037 0.3356734210152194 0.7371171509620214 1.0 0.9279720951889554 7 Q9UPT5 1 +Nuclear cyclin dependent protein kinase holoenzyme complex 0.4500875656742618 0.3225048376160597 0.7470702734930528 1.0 0.9366715566968068 4 P50750,Q9NYV4,Q14004 3 +Emc complex 0.4415195792696536 0.3182793362655552 0.7502730572372105 1.0 0.9380993246611063 5 Q9NPA0 1 +Intermediate filament cytoskeleton 0.2792625536303929 0.3159641336855446 0.7520297317499887 1.0 0.9389686852894736 37 Q3SXM5,Q16352,O14786,P07197,P48729,P08670 6 +Early endosome 0.2475136783669008 0.3119214376558787 0.7551002298642522 1.0 0.9389686852894736 109 O14786,Q9UIQ6,O95630,P10321,Q9Y5X2,P04083,Q12768,Q15043,Q5T9L3,P42858,Q5VW38,Q5VYK3,Q96L92,P05067,Q9H223,Q99523,Q92542,Q9BUN8,Q9Y2I1,P01889,P04439,Q92544,Q8IV08,Q13510 24 +Plasma membrane raft 0.3126345746291282 0.3045083356292654 0.7607406431798331 1.0 0.9432770221354946 23 Q9HD47,P09601 2 +Somatodendritic compartment 0.2437600402100692 0.2954896497316571 0.7676198578687012 1.0 0.9432770221354946 160 P20020,Q13641,P62753,P27695,O14965,O94832,O00264,Q9UBN7,Q9UQB8,P50897,O75592,P21964,P30153,P07900,Q14457,O15020,Q9H845,P98179,P33176,Q99729,Q13277,Q7L576,Q14168,Q16637,P23634,P42574,P04350,Q9H2U1,P42858,P55011,Q9UKA9,P23246,P54646,Q9BTU6,Q06787,P05067,P61586,Q9Y4G8,P51114,P27824,P42345,Q00839,P51116,O76024,P46934,Q9Y366,P52294,O60313 48 +Exocytic vesicle 0.2784929806026548 0.2929853875470872 0.7695333208967097 1.0 0.9432770221354946 36 P20020,Q92542,O76024,Q13277,P05067,Q15907,P50897 7 +Spliceosomal complex 0.2441007311795801 0.2924014451268885 0.7699797034373344 1.0 0.9432770221354946 127 P55769,Q14011,P61978,Q9BWJ5,P52756,P17844,P67809,P11940,P98179,P51991,Q13595,P07910,Q15427,O60506,P52597,O43390,P62995,Q9UKA9,P31943,P26368,Q9UKM9,P22626,P31942,P62316,Q14562,Q6P2Q9,P38159,Q00839,O95391,Q01081,O75400 31 +Dihydrolipoyl dehydrogenase complex 0.4252932345609254 0.2893765753780722 0.7722932186906997 1.0 0.9435679244487176 6 O14874,Q02218,P21953 3 +Sarcoplasm 0.3383472678300731 0.286054947227636 0.7748360372009238 1.0 0.9454039702223352 16 P14625,O43852,P16615 3 +Neuromuscular junction 0.337432122048532 0.2813142180021016 0.7784694060808897 1.0 0.9458179971038164 16 P05067,P57105 2 +Golgi cis cisterna 0.3526837806301027 0.2810967442289754 0.7786361982672001 1.0 0.9458179971038164 2 Q08379 1 +Rna cap binding complex 0.378857048707633 0.2726654674254689 0.7851103821550058 1.0 0.9490230550251334 8 Q06787 1 +Endoplasmic reticulum tubular network 0.3581408407960457 0.268064049550371 0.7886500176985125 1.0 0.9495502831256069 12 P50402,Q9NQC3 2 +Presynaptic cytosol 0.4234236191719712 0.259761311413685 0.795047895744208 1.0 0.9544739308271069 5 Q9UQB8 1 +Chloride channel complex 0.4123773864448399 0.24704679867821 0.8048720061790682 1.0 0.9601425900482584 6 Q9C0H2 1 +Er to golgi transport vesicle membrane 0.3049262969084648 0.2423472182735729 0.8085111291055378 1.0 0.9614280178327432 22 Q13190,P10321,P49257,P01889,Q9Y3B3,P04439,O95487 7 +Cuticular plate 0.3819667347534379 0.2417892993551696 0.8089434308203938 1.0 0.9614280178327432 3 Q01082,Q12965 2 +Intrinsic component of mitochondrial outer membrane 0.3570212695620068 0.2406160082975909 0.8098527418314445 1.0 0.9614280178327432 11 Q15388,Q8TB36,Q9BWH2,P50416,P57105,Q8IXI2,Q8IWA4 7 +Mediator complex 0.3507899356348745 0.2363245467803404 0.8131808407376577 1.0 0.9614280178327432 12 Q15648,Q9NYF8,O60244,P50750,P11802,O75448,Q9Y2W1,Q9NVC6,Q9NPJ6,Q9ULK4,Q13503 11 +Synaptonemal structure 0.3651244676258007 0.2362137324910539 0.8132668240147025 1.0 0.9614280178327432 9 Q92791 1 +Main axon 0.3499250250822007 0.2326743739755838 0.8160142697250392 1.0 0.9633207417922866 12 Q14168,P05067 2 +Recycling endosome membrane 0.2983599413733964 0.2290646984717918 0.8188186305473282 1.0 0.9641271180926442 24 O15127,P01889,P04439,Q15907 4 +Cornified envelope 0.3830883835270163 0.2148721374203352 0.8298670086203883 1.0 0.9720263604787972 7 P04083 1 +Organellar ribosome 0.2497436828360148 0.2056752380666275 0.8370446021759965 1.0 0.9767311211527354 47 Q9NVS2,Q14197,Q9Y291,Q5T653,Q9BYC9,Q9NQ50,P82914,Q9H2W6,P82933,Q9NP92,Q567V2,Q7Z7H8,Q9P015,P09001,Q9BRJ2 15 +Photoreceptor connecting cilium 0.395317540503346 0.1952587255737367 0.8451904073272694 1.0 0.9789992183886111 6 P41208,Q9Y366 2 +Centriolar satellite 0.2734640951852741 0.1942528002829893 0.8459779415186843 1.0 0.9789992183886111 31 P33176,Q9UPT5,Q86UY6,Q13045,P53350,Q03518 6 +Spectrin 0.3994176967880344 0.189740889585993 0.8495121775410044 1.0 0.9799575753613872 5 P05771,O15020,Q13813 3 +Ciliary tip 0.3445521092161374 0.1757689098809099 0.8604754956487115 1.0 0.9863458077486492 10 A0AVF1,Q9Y366,Q9P2L0,Q9Y496,Q7Z3E5 5 +Transport vesicle membrane 0.2500566750191627 0.1733974359832058 0.8623390403689812 1.0 0.9863481388725072 42 Q86Y82,P20020,Q13190,O76024,Q15363,P10321,P49257,P01889,Q9Y3B3,P04439,Q15907,O75592,O95487 13 +Elongator holoenzyme complex 0.3580391012547512 0.1726197019171664 0.8629503644862948 1.0 0.9863481388725072 3 Q9H9T3,Q6IA86 2 +Core mediator complex 0.3503798947983669 0.171624425402136 0.863732803677135 1.0 0.9863481388725072 8 Q15648,O60244,O75448,Q9NVC6,Q9NPJ6,Q9ULK4,Q13503 7 +Intrinsic component of postsynaptic density membrane 0.3527866939013881 0.1589023282078468 0.8737458263590183 1.0 0.988447527384672 3 Q9BQT9,P23634 2 +Catalytic step 2 spliceosome 0.2471897860494223 0.1578277092969246 0.8745925634422915 1.0 0.988447527384672 68 P61978,O43390,Q00839,P38159,P51991,P31943,Q14562,O95391,P11940,P07910,Q9UKM9,P22626,P62316,Q01081,O60506,P52597,Q6P2Q9 17 +Synaptic membrane 0.2460577891332383 0.1545777354920026 0.8771542235017042 1.0 0.9892471329566368 50 P20020,Q92542,O14786,Q13277,Q9BTU6,Q06787,P57105,Q9UQB8,Q8NCG7,Q99720,Q14168 11 +Brush border membrane 0.3753361881287311 0.1410547874187119 0.8878266608612708 1.0 0.9949564324334996 6 Q14728 1 +Zonula adherens 0.3803049523422471 0.1408011188967317 0.8880270591207393 1.0 0.9949564324334996 5 Q6IQ23 1 +Rough endoplasmic reticulum membrane 0.3145405349793815 0.1292905529197892 0.8971277463716982 1.0 0.9957559567635004 14 Q5BJF2,Q96A33,P51571,Q9Y5M8 4 +Death inducing signaling complex 0.3769345777125515 0.123627421286372 0.901610279988573 1.0 0.9957559567635004 4 P49327 1 +Trans golgi network membrane 0.2858414112967286 0.1221689858472997 0.902765188141922 1.0 0.9957559567635004 20 O15127 1 +Presynapse 0.2321521743234657 0.1210167058576297 0.9036778030836692 1.0 0.9957559567635004 93 Q99623,P20020,Q13641,P27695,P11279,Q9UQB8,P50897,Q15907,O15020,P11166,Q13277,O75955,Q7L576,P42858,Q9BTU6,Q06787,P05067,P51114,P27824,Q92542,P51116,O76024,Q07021,O14936,Q96CX2 25 +Telomerase holoenzyme complex 0.3161635640697696 0.1199639124953933 0.9045117351136598 1.0 0.9957559567635004 13 Q00839,Q9BUR4,Q9NY12,P07910,Q15185,Q9NVN8 6 +Brca1 a complex 0.373321657910106 0.1160176649654712 0.907638541717475 1.0 0.9957559567635004 4 Q9NWV8,P38398,Q9NXR7 3 +Rnai effector complex 0.3467102385882684 0.1100051800603033 0.9124052667561038 1.0 0.9957559567635004 7 Q9HAV4 1 +Intraciliary transport particle 0.366955032550697 0.1031476470696124 0.9178457897724212 1.0 0.9957559567635004 4 A0AVF1 1 +Bloc complex 0.3279836591771325 0.1015988654816721 0.9190750800050352 1.0 0.9957559567635004 3 P78537,Q9UPZ3 2 +Rna polymerase ii transcription repressor complex 0.3256492559089751 0.0968489045066675 0.9228463862633742 1.0 0.9986516251350086 3 P35222,Q9UHI6 2 +Mrna editing complex 0.3555166374781139 0.0817595482885349 0.9348379241228202 1.0 1.0 4 Q8NDT2,Q96T37,Q69YN4 3 +Endoplasmic reticulum exit site 0.2771148900562645 0.0788123089031397 0.9371819134143686 1.0 1.0 19 Q96PC5,O95487,P04439 3 +B wich complex 0.3295354951796626 0.0701915263485165 0.9440412186860307 1.0 1.0 7 Q9NR30,Q9NY93,Q9BQG0,O75533,Q9UIG0,O60264 6 +Ap 3 adaptor complex 0.3104756346658988 0.0686680862694696 0.9452538216872396 1.0 1.0 3 Q9P253,Q92572 2 +Tight junction 0.2633050893818033 0.0643954384426362 0.9486553620857028 1.0 1.0 27 P78310,Q86UE4,Q92974,Q16625,Q9NR77 5 +Oxoglutarate dehydrogenase complex 0.3078494309892141 0.0642602334388086 0.9487630170981144 1.0 1.0 3 Q02218,P09622 2 +Synaptic vesicle membrane 0.2990239128325958 0.0630369677922111 0.949737066803118 1.0 1.0 13 P20020,Q15907 2 +Myelin sheath 0.3012642667993098 0.0596827209241719 0.9524083339050168 1.0 1.0 12 P04350,Q9NR77,P07900 3 +Neuron projection cytoplasm 0.2331582512959187 0.0546387672212587 0.956426253097618 1.0 1.0 43 Q00839,P27695,P33176,Q99729,P23246,Q06787,Q9UQB8,Q9UBN7,Q14168,O60313,Q9Y2T2,P27824 12 +Endoplasmic reticulum plasma membrane contact site 0.2955570592946279 0.0454269557579216 0.9637669955730206 1.0 1.0 3 Q9NTJ5 1 +Phagophore assembly site membrane 0.3304144775248171 0.0425484715272076 0.9660614720207354 1.0 1.0 4 P51149,Q9H0U4,Q7Z3C6 3 +Early endosome membrane 0.2314690487055181 0.0423857273435907 0.966191206054585 1.0 1.0 47 Q96L92,P10321,P01889,P04439,P04083,Q8IV08,Q15043 7 +Mitotic spindle pole 0.2679617063093679 0.0409755642516986 0.96731537639931 1.0 1.0 19 O14965,Q96DB5,P53350,P62699 4 +Cytosolic region 0.3140571907137988 0.0397886539925181 0.9682616218718316 1.0 1.0 7 Q9UQB8 1 +N terminal protein acetyltransferase complex 0.3151611587170668 0.0237100384502628 0.981083898732352 1.0 1.0 4 Q9BXJ9 1 +Commitment complex 0.3150640421844851 0.0225507810912822 0.9820086048300134 1.0 1.0 5 P26368 1 +Anchored component of plasma membrane 0.2687481762474568 0.0140456718156157 0.988793543783383 1.0 1.0 3 P36551,Q15334 2 +Female pronucleus 0.3041561064513498 0.0123059614462389 0.9901815111700728 1.0 1.0 4 P11166 1 +Spectrin associated cytoskeleton 0.2939287799182791 0.0032397630128309 0.997415047633374 1.0 1.0 4 Q01082,Q12955,O15020 3 +Magnesium dependent protein serine threonine phosphatase complex 0.2787220331149297 7.885377617259367e-05 0.999937083789496 1.0 1.0 9 Q16537,Q14738 2 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6366c70569ca90a99977cdeadac18f86a7e20444 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc 1 complex", "Bloc complex", "Blood microparticle", "Borc complex", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Calyx of held", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body fiber", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Checkpoint clamp complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition fiber", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dense core granule membrane", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fanconi anaemia nuclear complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle a", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mks complex", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Mon1 ccz1 complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal dense core vesicle membrane", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Periciliary membrane compartment", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class i", "Phosphatidylinositol 3 kinase complex class ia", "Phosphatidylinositol 3 kinase complex class iii", "Photoreceptor connecting cilium", "Photoreceptor disc membrane", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADNP", "ADPGK", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT4", "AGPAT5", "AGPS", "AGTPBP1", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR7A2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMOT", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAP1", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC8", "ARMC9", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATG3", "ATG7", "ATG9A", "ATL2", "ATL3", "ATM", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLOC1S1", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C12orf73", "C19orf70", "C1QBP", "C1orf35", "C21orf59", "C2CD2L", "C2CD5", "C2orf49", "C3orf58", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARS2", "CASK", "CASP3", "CAST", "CBFB", "CBL", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC115", "CCDC124", "CCDC22", "CCDC47", "CCDC58", "CCDC86", "CCDC93", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPU", "CENPV", "CEP170", "CEP250", "CEP290", "CEP44", "CEP55", "CEP97", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHM", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHTF18", "CHTF8", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIT", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CMPK1", "CNN2", "CNN3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG5", "COG7", "COG8", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREBBP", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTC", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF15", "DCAF16", "DCAF7", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DERA", "DERL1", "DERL2", "DFFA", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2A", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNTTIP2", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DR1", "DRG1", "DSC2", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUS2", "DUSP3", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOG", "ENO1", "ENO2", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "ETHE1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM105A", "FAM126A", "FAM129B", "FAM162A", "FAM208A", "FAM20B", "FAM49B", "FAM83D", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXL18", "FBXO22", "FCGRT", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FNDC3A", "FNTA", "FNTB", "FOCAD", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FSD1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "FYCO1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GGA1", "GGA2", "GGCX", "GGH", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNB1L", "GNG5", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOT2", "GPAA1", "GPATCH4", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEBP2", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK1", "HP1BP3", "HPF1", "HPS5", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90AB4P", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS14", "INTS3", "INTS4", "INTS6", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "ISCA2", "ISG20L2", "ISOC1", "IST1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPK1", "ITSN2", "IVD", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KATNB1", "KCTD10", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA1468", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNSTRN", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC59", "LRRC8A", "LRWD1", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCRS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METTL13", "METTL7B", "MFAP1", "MFGE8", "MFN1", "MFSD10", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOCS2", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPHOSPH10", "MPHOSPH6", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFR", "MTIF2", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NEU1", "NF1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NMD3", "NME1", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C3A", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT19", "NUDT21", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL8", "OSBPL9", "OTULIN", "OXA1L", "OXCT1", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PARS2", "PATL1", "PAWR", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXP", "PEF1", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF6", "PHIP", "PHLDB2", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "POMP", "PON2", "POP1", "POR", "POU2F1", "PPA2", "PPAN", "PPFIA1", "PPFIBP1", "PPIB", "PPID", "PPIE", "PPIF", "PPIH", "PPIL2", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF18", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PRUNE1", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTPA", "PTPN1", "PTPN23", "PTPRF", "PTRH2", "PUM1", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB36", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAF1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM7", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RGS10", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIOX2", "RIPK1", "RMC1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCRIB", "SCRN1", "SCYL1", "SCYL2", "SDAD1", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGK3", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3RF1", "SHCBP1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIN3A", "SIPA1", "SIRT1", "SIRT2", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLFN11", "SLIRP", "SLK", "SLMAP", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX14", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRA1", "SRCAP", "SREK1", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAMM41", "TAOK1", "TAP1", "TAP2", "TAPBP", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TCP11L1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFB2M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLN1", "TM7SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM192", "TMEM199", "TMEM201", "TMEM214", "TMEM33", "TMEM43", "TMEM87A", "TMEM97", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TNRC6A", "TOE1", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TONSL", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC13", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM25", "TRIM27", "TRIM28", "TRIO", "TRIP12", "TRIP13", "TRMT10C", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TTC1", "TTC19", "TTC26", "TTC28", "TTC37", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBQLN4", "UBR1", "UBR2", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UFD1", "UFL1", "UGGT1", "UHRF1", "ULK3", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP32", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMP1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "WAPL", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR35", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR47", "WDR48", "WDR5", "WDR61", "WDR62", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WLS", "WRAP53", "WRAP73", "WTAP", "WWP2", "XAB2", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO6", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YKT6", "YLPM1", "YME1L1", "YPEL5", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC11", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM2", "ZNF207", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB8", "ABCD3", "ABCD4", "ABHD10", "ABI1", "ABRAXAS2", "ACAD11", "ACAD9", "ACAP2", "ACAT2", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACTN4", "ADPGK", "AGPAT5", "AHCYL1", "AIFM1", "AKAP10", "ALDH2", "ALDH3A2", "ALG1", "ALG11", "ANAPC1", "ANAPC5", "ANK3", "ANKLE2", "ANKRD13A", "ANO6", "ANXA1", "ANXA11", "AP3M1", "AP3S1", "APEX1", "APOL2", "APOO", "APOOL", "APP", "ARHGEF2", "ARL6IP1", "ARMC9", "ASAH1", "ASNA1", "ATAD3A", "ATAD3B", "ATG9A", "ATL2", "ATM", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATR", "AURKA", "AURKB", "B3GALT6", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAIAP2", "BAZ1B", "BCAP31", "BCAS3", "BCKDHB", "BCKDK", "BCL2L13", "BCLAF1", "BECN1", "BICD2", "BLOC1S1", "BRCA1", "BRI3BP", "BSG", "C12orf73", "C19orf70", "C1QBP", "C3orf58", "CACYBP", "CALU", "CAMK2G", "CANX", "CASK", "CASP3", "CCDC47", "CD109", "CDC16", "CDC23", "CDC27", "CDK12", "CDK13", "CDK4", "CDK9", "CDKAL1", "CEP290", "CERS1", "CERS2", "CETN2", "CHCHD3", "CIRBP", "CISD1", "CKAP4", "CLCC1", "CLCN7", "CLN5", "CLPTM1", "CLPX", "CLSTN3", "CNNM4", "COA3", "COMT", "COQ8A", "COX15", "COX2", "COX4I1", "COX6B1", "COX7A2", "CPOX", "CPT1A", "CPT2", "CRK", "CRTAP", "CSNK1A1", "CTNNB1", "CTSA", "CXADR", "CYB5B", "CYB5R1", "CYC1", "CYFIP1", "CYP51A1", "DAGLB", "DCTN4", "DCTPP1", "DDRGK1", "DDX20", "DDX21", "DDX31", "DDX5", "DDX56", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX36", "DHX8", "DHX9", "DIABLO", "DLD", "DNAJB11", "DNAJC1", "DNAJC11", "DOLPP1", "DPM1", "DSE", "EARS2", "ECE1", "ECSIT", "EHD4", "ELP2", "ELP3", "EMC7", "EMD", "EPB41L3", "EPDR1", "EPHX1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERGIC3", "ERLIN1", "ESYT2", "ETFDH", "EXOC7", "FADS2", "FAM105A", "FAM162A", "FAM49B", "FAM8A1", "FAR1", "FAR2", "FASN", "FCGRT", "FDFT1", "FECH", "FGFR1OP", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "FKRP", "FLII", "FLOT1", "FMR1", "FOXRED1", "FUCA2", "FUNDC2", "FXR1", "FXR2", "GAA", "GADD45GIP1", "GALNT1", "GALNT2", "GALNT4", "GAR1", "GBA", "GDAP1", "GGCX", "GGH", "GLA", "GLB1", "GLDC", "GLG1", "GLUD1", "GM2A", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOSR1", "GPAA1", "GPD2", "GPR107", "GPR108", "GPR89B", "GTPBP8", "GUSB", "HACD3", "HADH", "HADHA", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HCCS", "HDAC6", "HEBP2", "HEXA", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMOX1", "HMOX2", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPR", "HNRNPU", "HPS5", "HS2ST1", "HSD17B12", "HSDL1", "HSP90AA1", "HSP90B1", "HTT", "ICMT", "IDH1", "IDH2", "IFT52", "IKBIP", "ILVBL", "IMMT", "INA", "INTS1", "IPO8", "ITM2B", "ITM2C", "JAGN1", "KCTD12", "KDELR1", "KDELR3", "KDSR", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIF3A", "KIF5B", "KIFBP", "KPNA1", "L2HGDH", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LBR", "LETM1", "LGALS3BP", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LNPEP", "LONP1", "LPCAT1", "LRPAP1", "LRRC59", "LSS", "MAGT1", "MAN1A2", "MAN2A1", "MATR3", "MBOAT7", "MCL1", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED4", "METTL7B", "MFGE8", "MFN1", "MFSD10", "MIA2", "MICU2", "MIEF1", "MIGA1", "MINPP1", "MIPEP", "MMAB", "MMS19", "MOV10", "MPP2", "MPP7", "MPV17L2", "MRPL10", "MRPL15", "MRPL2", "MRPL20", "MRPL3", "MRPL40", "MRPL45", "MRPL46", "MRPL58", "MRPS15", "MRPS18A", "MRPS25", "MRPS30", "MRPS33", "MRPS9", "MSH3", "MSH6", "MSMO1", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTO1", "MTOR", "MTX1", "MYBBP1A", "MYCBP2", "MYDGF", "MYO1D", "MYO1E", "NAA15", "NAA40", "NAGLU", "NAP1L1", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEU1", "NISCH", "NLN", "NNT", "NPC1", "NPC2", "NRDC", "NRM", "NRP1", "NSUN2", "NUBP2", "NUCB1", "NUCB2", "NUDT19", "NUP160", "NUP188", "NUP214", "NUP37", "NUP54", "NUP85", "NUP88", "NUP93", "NUP98", "OCIAD1", "OCLN", "OGDH", "OLA1", "OPA1", "OS9", "OSBP", "OSBPL8", "OSBPL9", "OXA1L", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "PABPC1", "PCM1", "PCNT", "PCYOX1", "PDHB", "PDK1", "PDK3", "PDSS1", "PDSS2", "PGRMC1", "PGRMC2", "PHB2", "PI4K2A", "PIGU", "PIP4K2C", "PISD", "PITRM1", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLEKHA7", "PLK1", "PLOD3", "PMPCA", "PNPLA4", "PNPLA8", "POLDIP2", "POLE", "POLRMT", "POMGNT2", "PON2", "POR", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP2R5E", "PPT1", "PRCP", "PREB", "PREPL", "PRKAA2", "PRKAR1A", "PRKCB", "PRKRA", "PRMT5", "PRPF40A", "PRPF8", "PSAP", "PSMB1", "PSMB2", "PSMB6", "PSMF1", "PTBP2", "PTDSS1", "PTGES2", "PTGES3", "PXMP2", "QSOX2", "RAB11B", "RAB1B", "RAB24", "RAB35", "RAB5B", "RAB7A", "RALY", "RANBP2", "RANGRF", "RAPGEF2", "RBM15", "RBM15B", "RBM3", "RBM4", "RBM5", "RBMX", "RCN2", "RER1", "RETSAT", "RHBDD2", "RHOA", "RHOT1", "RINT1", "RMDN1", "RMND1", "RNASET2", "RPL10", "RPL27A", "RPL4", "RPN1", "RPN2", "RPS12", "RPS23", "RPS6", "RRM2", "RTN3", "RTN4", "SACM1L", "SAMM50", "SC5D", "SCAMP2", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SDCBP", "SDF4", "SDHB", "SEC11A", "SEC24B", "SEC62", "SEC63", "SEL1L", "SF3B1", "SF3B4", "SF3B5", "SFPQ", "SFXN2", "SFXN4", "SGPL1", "SHMT2", "SIGMAR1", "SIRT2", "SLC12A2", "SLC16A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC2A1", "SLC35A4", "SLC35B2", "SLC39A14", "SLC4A7", "SLC7A1", "SLMAP", "SLU7", "SMARCA5", "SMN1*", "SMPD4", "SNRPD2", "SNTB2", "SNU13", "SNX27", "SNX8", "SOAT1", "SORT1", "SPNS1", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRPRB", "SSBP1", "SSR1", "SSR4", "STAMBP", "STARD3", "STT3A", "STT3B", "STX12", "STX18", "STX3", "STX5", "STX8", "STXBP3", "SUN1", "SUN2", "SURF4", "SUZ12", "SYNCRIP", "SYNJ2BP", "TAMM41", "TAP1", "TAP2", "TAPBP", "TARS2", "TBL2", "TDRKH", "TECR", "TEX264", "TFB2M", "THRAP3", "TIA1", "TIAL1", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM8B", "TIMM9", "TIMMDC1", "TM7SF2", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED7", "TMED9", "TMEM126A", "TMEM192", "TMEM199", "TMEM201", "TMEM33", "TMEM87A", "TMEM97", "TMLHE", "TMTC3", "TMX2", "TMX4", "TOMM20", "TOMM22", "TOMM5", "TOR1AIP2", "TPBG", "TPP1", "TRA2A", "TRA2B", "TRAM1", "TRAPPC5", "TRMU", "TSPAN3", "TSPAN6", "TSPO", "TTC19", "TTC26", "TTYH3", "TUBB", "TUBB4A", "TUBGCP3", "TWNK", "TXNDC12", "TYSND1", "U2AF1", "U2AF2", "UBAP2L", "UNC119B", "UQCR10", "UQCRC1", "UQCRQ", "USP4", "VAMP7", "VANGL1", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13A", "VPS18", "WASHC5", "WDR35", "WDR48", "WFS1", "WLS", "WRAP53", "WRAP73", "XPO4", "XPO5", "YBX1", "YKT6", "YPEL5", "YTHDC2", "ZADH2", "ZMPSTE24", "ZNF622"]} \ No newline at end of file diff --git a/msigdb_gomf/advanced/idx2term.json b/msigdb_gomf/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..48c78d44e05be5fc07f15f05ac66445f58aa8e84 --- /dev/null +++ b/msigdb_gomf/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter activity", "1": "Ion transmembrane transporter activity", "2": "Active transmembrane transporter activity", "3": "Cation transmembrane transporter activity", "4": "Anion transmembrane transporter activity", "5": "Inorganic molecular entity transmembrane transporter activity", "6": "Organic anion transmembrane transporter activity", "7": "Hydrolase activity hydrolyzing o glycosyl compounds", "8": "Active ion transmembrane transporter activity", "9": "Hydrolase activity acting on glycosyl bonds"} \ No newline at end of file diff --git a/msigdb_gomf/advanced/plot_0.png b/msigdb_gomf/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..ec92e601899345e49ec5793b0584e6e71cdd0c08 --- /dev/null +++ b/msigdb_gomf/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:da57f5b63418e5cd3c093ca620925ca9c2e42095edbf9ffd58bb9d832ba00de5 +size 219451 diff --git a/msigdb_gomf/advanced/plot_1.png b/msigdb_gomf/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..1172d0dfc0635b65db8ca40c9cad455b7672eafa --- /dev/null +++ b/msigdb_gomf/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c3d39d21403e378591b48855d8a288ff9bb67ee0367983029094507b3140d093 +size 216223 diff --git a/msigdb_gomf/advanced/plot_2.png b/msigdb_gomf/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..501bc2b8557a6e3af56904523df13ec72dda559d --- /dev/null +++ b/msigdb_gomf/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dd7728b3ffe95098370f74c8c435a7d4640b77f6657d983a85d310b19f8731ee +size 215130 diff --git a/msigdb_gomf/advanced/plot_3.png b/msigdb_gomf/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..9999c22c932ccdd78459088dddd0a261f6936f9d --- /dev/null +++ b/msigdb_gomf/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:910f508b378360bed6bdf756dcfef96b8d93bf3cfe716a55a893e256af15edd7 +size 211791 diff --git a/msigdb_gomf/advanced/plot_4.png b/msigdb_gomf/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..007fa52f9e058d0ebd6ba6b1dd1b3df252667d2a --- /dev/null +++ b/msigdb_gomf/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b2fd1d0efdd55f2c0705a6c91cf9ea23a90c94b7a94ad2b004509fb213dd4fbf +size 206156 diff --git a/msigdb_gomf/advanced/plot_5.png b/msigdb_gomf/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..773ee9c876f3383e3ceefe2c24f3e71d85518b2f --- /dev/null +++ b/msigdb_gomf/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6785eef917f6574f44995092dbed7917234f143dee6ab17e9fb6e647741d752f +size 216009 diff --git a/msigdb_gomf/advanced/plot_6.png b/msigdb_gomf/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..2fcdc08647681e4d521dd594555a89c20fe70b3d --- /dev/null +++ b/msigdb_gomf/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a4571849700b71559211d209fcb344a5f01c0828f7ab1e621546f254d82df122 +size 203760 diff --git a/msigdb_gomf/advanced/plot_7.png b/msigdb_gomf/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..64ca74e86434b810d019800e20e3b9cd08b604c9 --- /dev/null +++ b/msigdb_gomf/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:273aacc1892f7559ffb625152ccc80cc3979227dcfbf6876dfb098c6ef73ce64 +size 203845 diff --git a/msigdb_gomf/advanced/plot_8.png b/msigdb_gomf/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..e2612712573b690fca6a43c83c894bc97f097c62 --- /dev/null +++ b/msigdb_gomf/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:61d461b5333d65dcca8136f8771748121b1d98769ce91209dd35cf3bcc58cd7e +size 212486 diff --git a/msigdb_gomf/advanced/plot_9.png b/msigdb_gomf/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..f6b4f6d1c329feb4e2d0f087df188c4f17d71c26 --- /dev/null +++ b/msigdb_gomf/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d6c4830620e3136f39aea7f8ad87c16e2cd084e038ba716f3a5d01b7c4b8584d +size 205440 diff --git a/msigdb_gomf/basic/idx2term.json b/msigdb_gomf/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..7e39d3c18458ff40d7b9f85c909062f96e60d2b6 --- /dev/null +++ b/msigdb_gomf/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter activity", "1": "Ion transmembrane transporter activity", "2": "Active transmembrane transporter activity", "3": "Cation transmembrane transporter activity", "4": "Anion transmembrane transporter activity", "5": "Inorganic molecular entity transmembrane transporter activity", "6": "Organic anion transmembrane transporter activity", "7": "Hydrolase activity hydrolyzing o glycosyl compounds", "8": "Active ion transmembrane transporter activity", "9": "Hydrolase activity acting on glycosyl bonds", "10": "Peptide binding", "11": "Tetrapyrrole binding", "12": "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "13": "Steroid binding", "14": "Primary active transmembrane transporter activity", "15": "Amide binding", "16": "Secondary active transmembrane transporter activity", "17": "Sterol binding", "18": "Organic acid transmembrane transporter activity", "19": "Protein transporter activity", "20": "Lipid binding", "21": "Hexosyltransferase activity", "22": "Lipid transporter activity", "23": "Endopeptidase activity", "24": "Serine hydrolase activity", "25": "Proton transmembrane transporter activity", "26": "Molecular transducer activity", "27": "Metal ion transmembrane transporter activity", "28": "Peptide antigen binding", "29": "Glycolipid binding", "30": "Alcohol binding", "31": "Oxidoreduction driven active transmembrane transporter activity", "32": "Cholesterol binding", "33": "Nucleobase containing compound transmembrane transporter activity", "34": "Metalloendopeptidase activity", "35": "Macromolecule transmembrane transporter activity", "36": "Antigen binding", "37": "Glycosyltransferase activity", "38": "Udp glycosyltransferase activity", "39": "Electron transfer activity", "40": "Symporter activity", "41": "Monooxygenase activity", "42": "Peptidase activity", "43": "Organophosphate ester transmembrane transporter activity", "44": "Nucleotide transmembrane transporter activity", "45": "Signal sequence binding", "46": "Antiporter activity", "47": "Solute cation symporter activity", "48": "Fad binding", "49": "Calcium ion binding"} \ No newline at end of file diff --git a/msigdb_gomf/basic/plot_0.png b/msigdb_gomf/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..c2c34bf966a06b2654511e536aaa29aa0551617b --- /dev/null +++ b/msigdb_gomf/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:30b9a4140cb85c5a3edfd1a93488037d5b7217223c33fa022b692176a177e472 +size 139242 diff --git a/msigdb_gomf/basic/plot_1.png b/msigdb_gomf/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..21de5cfa935422b0b987ea7debcfdc16af7b6331 --- /dev/null +++ b/msigdb_gomf/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a29d5077202426c04bca367d32e2de4e7bca539d989d7aa2eca36842c4194c07 +size 144408 diff --git a/msigdb_gomf/basic/plot_10.png b/msigdb_gomf/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..f195f32f0d04e659d2eea837e94e429afc41f50c --- /dev/null +++ b/msigdb_gomf/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1d53c2e89399300da2e171e24ab70a817baa1b0f3f883292f8f1f1622fb9fed8 +size 143017 diff --git a/msigdb_gomf/basic/plot_11.png b/msigdb_gomf/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..808b193611254bfd255f41a632199714ea8d0e78 --- /dev/null +++ b/msigdb_gomf/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:44efd421aad9c40ccb7203e107121de0b6f28f8c4475f59db8998002e323e09e +size 140811 diff --git a/msigdb_gomf/basic/plot_12.png b/msigdb_gomf/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..5a8ce28cfde4e30c26f83c80f14f41ab50a73046 --- /dev/null +++ b/msigdb_gomf/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e29822fe135ce415dc7b5eea337d1654920e9fc1136f705a34ebad574584ccee +size 149666 diff --git a/msigdb_gomf/basic/plot_13.png b/msigdb_gomf/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..bca42c9c7ffd9db5ce81a204a347921885103d74 --- /dev/null +++ b/msigdb_gomf/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d8840c974357615f556419bebfae679ce25c191672b71cd6df1a4abdb28546c4 +size 126509 diff --git a/msigdb_gomf/basic/plot_14.png b/msigdb_gomf/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..b16ecac565c985ee4233431064da729d80f0fc32 --- /dev/null +++ b/msigdb_gomf/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:08f7e278bc7b9ec04214b03de17587db3b403df1d253dc6ad0425cb168072e73 +size 152776 diff --git a/msigdb_gomf/basic/plot_15.png b/msigdb_gomf/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..4a33051c3a333333802f726b64d7bd77c7cc5200 --- /dev/null +++ b/msigdb_gomf/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d0c500e784044b7abe1ef719a7c2d828c748f7889e0c5ea0b38a32837fbd38ee +size 136067 diff --git a/msigdb_gomf/basic/plot_16.png b/msigdb_gomf/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..5ac2c9e1221ed450e9e0aa14673f5563f455db52 --- /dev/null +++ b/msigdb_gomf/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:74151bc3a86adb4b76c4d03c25746dfd5fcb7ce976ee69986d777c5cd16cd812 +size 148637 diff --git a/msigdb_gomf/basic/plot_17.png b/msigdb_gomf/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..e259714b18a6855386007d03cbfeb702177929fa --- /dev/null +++ b/msigdb_gomf/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f4a0297c359d5b636197c9682c99e4c05117f023aa0c5b7369350417d04d0008 +size 136099 diff --git a/msigdb_gomf/basic/plot_18.png b/msigdb_gomf/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..0b4048ed778c765ac7587e32d548936fdd4951c6 --- /dev/null +++ b/msigdb_gomf/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b448da343b1b62ebc59dd5a96ca4aa923cbb410ce62ac8fcd8e65df68f6e65af +size 147406 diff --git a/msigdb_gomf/basic/plot_19.png b/msigdb_gomf/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..411d4a4cd196eeb2b5df7febe7f55e1a1c94a284 --- /dev/null +++ b/msigdb_gomf/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:32744ee04bfb993805237a9834ebbcacac25c2d7bee0577afd2029acd3b1031d +size 142118 diff --git a/msigdb_gomf/basic/plot_2.png b/msigdb_gomf/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..99f67790d16aecb29c7584becb855ae1dd88f91c --- /dev/null +++ b/msigdb_gomf/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e9db5d8657ac094d9d3d12df2623f6afb559fb05f73e0b87f345dbfa57a233a8 +size 149243 diff --git a/msigdb_gomf/basic/plot_20.png b/msigdb_gomf/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..cf13e84cad6a6c209e807cdcfa2a9ba1087a3ed5 --- /dev/null +++ b/msigdb_gomf/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:da6c8da4bf89ef4867effd01bb6dd76763038fc70139b0998366536d12b5ef9e +size 142858 diff --git a/msigdb_gomf/basic/plot_21.png b/msigdb_gomf/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..6614ea261cafa3de1cc58ce3453e114a69a1f884 --- /dev/null +++ b/msigdb_gomf/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:881a838df11c838d5917f1264a465ad80c7bab2da9c2c35a582265441ddc151e +size 143583 diff --git a/msigdb_gomf/basic/plot_22.png b/msigdb_gomf/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..5a8fc39c44c7c3e0be34694b04c48314fa49762b --- /dev/null +++ b/msigdb_gomf/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2e5c45af562b2bb28230bb52e4dfa9a0d7185a238faa5ce5e63092e5bf96e3c8 +size 140692 diff --git a/msigdb_gomf/basic/plot_23.png b/msigdb_gomf/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..8e13d29b6c6acf9df30146d4cee3b3513ffff6e6 --- /dev/null +++ b/msigdb_gomf/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4ecf52593395c1b24dca837ee510936aed85cd6725439d802e53129360bfd418 +size 146605 diff --git a/msigdb_gomf/basic/plot_24.png b/msigdb_gomf/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..8c217b6b52498d0917cedcbce2923beaa33786e0 --- /dev/null +++ b/msigdb_gomf/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:89b46afa15cebc5c529e0a621b9b59fe2aebbffaaecd865b63e35982d63ba0bf +size 143039 diff --git a/msigdb_gomf/basic/plot_25.png b/msigdb_gomf/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..b387c076ce851fac79b65755840c29a93b60fd71 --- /dev/null +++ b/msigdb_gomf/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b669c3e50cded55f6d2244a1a2bfde94d35f0b2c8dffcf894c8d3d503c5aa97e +size 145952 diff --git a/msigdb_gomf/basic/plot_26.png b/msigdb_gomf/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..0554cecce79cd959d0538be795284bd557e20aac --- /dev/null +++ b/msigdb_gomf/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1f3635090218419d50e5f4dc6cbb664fa4fe8ce3d1fa8023f85300460ceaa7cf +size 141880 diff --git a/msigdb_gomf/basic/plot_27.png b/msigdb_gomf/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..fe3f9013cb4da75353248670c0c80f9f84e43c5f --- /dev/null +++ b/msigdb_gomf/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:143b871a9a05bea40e691453d97a5311e4e07b2499173e2d7f5add16279ca11a +size 147216 diff --git a/msigdb_gomf/basic/plot_28.png b/msigdb_gomf/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..736823a66911b987f77a8b2ae40bc1344dcb4903 --- /dev/null +++ b/msigdb_gomf/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fb8938908638ba9298dd5fc6592654d9cd301d35e63a37b1b1652f7d2403fd7c +size 139052 diff --git a/msigdb_gomf/basic/plot_29.png b/msigdb_gomf/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..aeef31bee1df495b609f372e5e7f0d449e8cb7e4 --- /dev/null +++ b/msigdb_gomf/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9922f03ef374afbe36cd97c887c85d044e57a959f135436b62b62a98af9c8d8f +size 138758 diff --git a/msigdb_gomf/basic/plot_3.png b/msigdb_gomf/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..d9c6ccd81a6e8ec15daf63986cc2611d12942960 --- /dev/null +++ b/msigdb_gomf/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5f266bc3f6cc2977f5f44522558ee59caf30aadf37405a0ba9a7b4893187c075 +size 148891 diff --git a/msigdb_gomf/basic/plot_30.png b/msigdb_gomf/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..d14e67091cf5346928c3456fe1863aa577fc94e4 --- /dev/null +++ b/msigdb_gomf/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7e524361e2531af1bd3b2d4c15b633fa9ccc4cbd504c7e8e4d73725627c504a2 +size 135364 diff --git a/msigdb_gomf/basic/plot_31.png b/msigdb_gomf/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..57f8d208fe10a302161a9982b4f40457b12b1a9e --- /dev/null +++ b/msigdb_gomf/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d4bcb5558c6d7b04e2befb44fab66ffead6ebbf85058d1d2add71c1728e561fd +size 147260 diff --git a/msigdb_gomf/basic/plot_32.png b/msigdb_gomf/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..b25b3f0d912873aba9d1a5d4b963026d2ab382b0 --- /dev/null +++ b/msigdb_gomf/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:29cf0acc34875b3965db92cbf975705ca0af8bcf294e3feca9ca64e8555f03ac +size 134857 diff --git a/msigdb_gomf/basic/plot_33.png b/msigdb_gomf/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..2c239a88857d0695634a62bf5674ed77e65013a9 --- /dev/null +++ b/msigdb_gomf/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0efbc255572f406ccb6e9b7d5e544a2b1ee44f1c5af6b5a55985d00e0d94706e +size 149501 diff --git a/msigdb_gomf/basic/plot_34.png b/msigdb_gomf/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..fed1fb099d0435b45ba903c609af313c0d6d6088 --- /dev/null +++ b/msigdb_gomf/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eafe67c8a1340c48ee260e98523aa3e1314f0fc4a2e54284b8dc1775eeb2437e +size 141733 diff --git a/msigdb_gomf/basic/plot_35.png b/msigdb_gomf/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..236bb1c20537a4d79b3f574f8a3dd70e5a7496a1 --- /dev/null +++ b/msigdb_gomf/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:461d9747256d350a2671877877ae57254f411fe313d8adbbdaa8f60bef783b5d +size 141371 diff --git a/msigdb_gomf/basic/plot_36.png b/msigdb_gomf/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..9219f1127d7fd9313bac3ccfef1eeb480aa227ff --- /dev/null +++ b/msigdb_gomf/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d700c5426010c5169515f63bd176c8b68acf1f94e4f06b9499df8802c979eb82 +size 134588 diff --git a/msigdb_gomf/basic/plot_37.png b/msigdb_gomf/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..a6afc79a3a5ce6d3b7c3a4a01862c4b975dd5085 --- /dev/null +++ b/msigdb_gomf/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4840169f1cbaf10ab73c17511e5f162bc4103f1463b370abb3b427f55643f795 +size 142687 diff --git a/msigdb_gomf/basic/plot_38.png b/msigdb_gomf/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..4398cc6760ecb4a2ad9749f9b594b06fbb0c2bf8 --- /dev/null +++ b/msigdb_gomf/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:713e7aacfd837a03676bf5baca85f9bf31bd66f237bf46c0c0561da44856912a +size 144518 diff --git a/msigdb_gomf/basic/plot_39.png b/msigdb_gomf/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..d4ce5b1b9684618418b870d7743adc73e6498ce3 --- /dev/null +++ b/msigdb_gomf/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:beebf153f802fcde9d81f061aa6df30ef20675992472dd66737213efa3f1a41a +size 145218 diff --git a/msigdb_gomf/basic/plot_4.png b/msigdb_gomf/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..915f56444eb1f823b7d65535b66a277ed3263128 --- /dev/null +++ b/msigdb_gomf/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6b9dc81b027b5c2cecd5e0368c183fac0c0d8b80187bef8c66f1c38ea24a7d31 +size 142289 diff --git a/msigdb_gomf/basic/plot_40.png b/msigdb_gomf/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..5480963e7856e959ef4610312ac844dc88fbf6d9 --- /dev/null +++ b/msigdb_gomf/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:220f1414024fe1560d4e4d664892e8f41703164326cec3b63b00cf3f1b2b97fd +size 136366 diff --git a/msigdb_gomf/basic/plot_41.png b/msigdb_gomf/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..c745cba0ca487a0c2289bfce0225c3a713684912 --- /dev/null +++ b/msigdb_gomf/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8004813c57780ab7c5515f66cdb4118e5e0a574d11061b78406fd450919a5a20 +size 138860 diff --git a/msigdb_gomf/basic/plot_42.png b/msigdb_gomf/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..4e9c61d9386bdeeba0dc0a1b594d7f5d842274ed --- /dev/null +++ b/msigdb_gomf/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b75b8d5dda48725bec07da68dd6aa6edf9051f58ffd78c927daf83bc2c14ca83 +size 142355 diff --git a/msigdb_gomf/basic/plot_43.png b/msigdb_gomf/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..33b2e2a3b0c956f90191665a4f22ebfa52bc2f0e --- /dev/null +++ b/msigdb_gomf/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fdb02a2ce4d6ae1819b3cba30cda41fa85d68d7acac9246bf9a8872998ea0a94 +size 141787 diff --git a/msigdb_gomf/basic/plot_44.png b/msigdb_gomf/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..d7a73df6a3d030e296ea13a2db1a7ec5dec7d16f --- /dev/null +++ b/msigdb_gomf/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a0b0edf3675edbe6f1d5cebe6e6fd75f81819a2ba91d1656d713d9a4eaa59670 +size 141751 diff --git a/msigdb_gomf/basic/plot_45.png b/msigdb_gomf/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..5d48783baeb711120dbb088efb6ed32de04489b3 --- /dev/null +++ b/msigdb_gomf/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:07c264c0f90d33686524a4d66b88ab3e4bf887ef6fa19953e7b7cc5cbe629c4e +size 137147 diff --git a/msigdb_gomf/basic/plot_46.png b/msigdb_gomf/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..feb6ef4a729a6dd80d5d5c50fe217550fe3e8702 --- /dev/null +++ b/msigdb_gomf/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:957956914891fb59b7dd103ff108ef4b438052914f901e389687559b03f322d7 +size 131196 diff --git a/msigdb_gomf/basic/plot_47.png b/msigdb_gomf/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..99980ca11f270b3b4aaf4c42aa2761b623a29d4c --- /dev/null +++ b/msigdb_gomf/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e80d33fed7b16ac09c8071a12ab969f9db056298f4c50e836cd5d66b30d8d19d +size 138061 diff --git a/msigdb_gomf/basic/plot_48.png b/msigdb_gomf/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..fb741c065be44f3a6e15f821603b760ca6874ce4 --- /dev/null +++ b/msigdb_gomf/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f13e97108701a31dc4aabc5a0f64bae287ca8266cead0992b4cd6f138979356a +size 126451 diff --git a/msigdb_gomf/basic/plot_49.png b/msigdb_gomf/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..be8476eabcb998fa2dbffb1b51fad2a1c6acd4a3 --- /dev/null +++ b/msigdb_gomf/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9cae24ae817a358763aee9a58a3925a289c1dc34a0d9bbd0d49af5e386cd6fd2 +size 140688 diff --git a/msigdb_gomf/basic/plot_5.png b/msigdb_gomf/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..edf11b4768b4ffc18d75f9948b755b896e09f96b --- /dev/null +++ b/msigdb_gomf/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ab9b490ba752f10434f19fd93819012973df2874ee0f190dbf8f3fae1e4aee6b +size 146490 diff --git a/msigdb_gomf/basic/plot_6.png b/msigdb_gomf/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..c2693238c2657de63028dc02c301875bca89443d --- /dev/null +++ b/msigdb_gomf/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0e03950ec4e88264b3dfe57403254229844d1aac9d2eeca360cd5d1a310662ea +size 148648 diff --git a/msigdb_gomf/basic/plot_7.png b/msigdb_gomf/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..74f8046b5d4b01947983a8775cf8c33a8ca2804f --- /dev/null +++ b/msigdb_gomf/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7fffaf7355cb383f9749763ea3317b1cb58d699149ee722f139df6570575a94c +size 151316 diff --git a/msigdb_gomf/basic/plot_8.png b/msigdb_gomf/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..715a9de3ffcf1c4aa28ca03e85de4997d722b765 --- /dev/null +++ b/msigdb_gomf/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2f7ab3f206a8ffdf9b6b80fb5edb41f31badc1c325772634a7771777ce7d42fe +size 148630 diff --git a/msigdb_gomf/basic/plot_9.png b/msigdb_gomf/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..1af2f0c7bc611c96b64ba4c78b4044d42022051b --- /dev/null +++ b/msigdb_gomf/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f29f7ecd295886e51be16076200fb8e585a5fab321720afcabeb76ba8ef9d664 +size 149804 diff --git a/msigdb_gomf/consensus.joblib b/msigdb_gomf/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e1a598ac4aad7206f3e1f2ce51a0d22c021aa131 --- /dev/null +++ b/msigdb_gomf/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:85dfdceab9a1354a77112264ac359ceb462a37c18dc907c0f4035db1c4dd73bf +size 294057 diff --git a/msigdb_gomf/df_merge.tsv b/msigdb_gomf/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..d044644e4a97f73865f162d6ff5461e772a4688c --- /dev/null +++ b/msigdb_gomf/df_merge.tsv @@ -0,0 +1,73 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transporter activity 96 173 6.587536831757315 4.471830748321565e-11 62.22330097087379 172.27912621359224 2.173366592838491 0.2707201784543502 25.984753572620328 19.29276868436311 2.593156143256053 0.3916539604106395 6.721624506185172e-15 1.3498031314995738e-12 2.62891323791822e-12 2.535023775516215e-15 8.793724208480734e-15 +Ion transmembrane transporter activity 52 95 4.924038332162267 8.477621878946214e-07 37.34466019417476 101.497572815534 2.0154097423383375 0.2561362875319209 17.172953606300336 11.579295798802024 2.277787478419462 0.3756175790939143 1.8274389389276077e-06 2.228205019445335e-07 9.732214111731292e-06 1.9886959550759047e-06 2.697922999125095e-06 +Active transmembrane transporter activity 35 74 4.474345510373875 7.664571925358743e-06 26.354368932038835 73.12621359223301 1.313035419122872 0.3239574057550545 11.878456281473593 8.663537710607383 1.88741562841277 0.3851687956916088 5.010896133352007e-05 0.0029850442420534 0.0036532159471918 0.0004283199077538 5.090397561385232e-06 +Cation transmembrane transporter activity 31 65 4.193166792353779 2.750870274170758e-05 25.62135922330097 70.51699029126213 1.766742880952279 0.2698419237572138 12.29126021871486 8.422243011776631 2.00238274385689 0.3706372466673562 0.0007602193895599 0.0008750126718088 0.0075285983084647 0.0005368671826434 0.0003611572596368 +Anion transmembrane transporter activity 27 43 3.9238519635325937 8.714429617828756e-05 18.594660194174757 45.61893203883495 1.6222323024349488 0.2373683627198559 9.346785472607134 6.017202751823004 1.8117646078257517 0.3183345645365742 0.0002053728572866 3.218480659711065e-05 0.0002301210091476 0.0002524168007504 0.0003885024837068 +Inorganic molecular entity transmembrane transporter activity 33 71 3.9235792004543 8.724306634078083e-05 28.058252427184467 75.9635922330097 1.5031303400189615 0.2894264293069549 11.721339963426631 9.38477049228959 2.153051736566399 0.3821536813265525 0.0001575989609573 2.096539998195203e-05 0.0006169806372766 9.384563088987948e-05 0.0003184634382904 +Organic anion transmembrane transporter activity 18 28 3.619134776706773 0.0002955896682952 12.951456310679612 30.182038834951456 1.56101282472555 0.2452312368187786 6.880574373146614 3.5222410835885483 1.575669523214114 0.314839840161206 0.0095405041050534 0.0082661149627475 0.0096196388866906 0.017553407397255 0.0080072027585734 +Hydrolase activity hydrolyzing o glycosyl compounds 12 23 3.5944270876953843 0.0003251061704865 8.830097087378642 20.84223300970874 0.5983257656540719 0.2104301479001341 3.2223833352824554 2.4557961681485057 1.9540573665272416 0.2728112677124137 6.046732873417432e-08 0.0230307909850112 0.0012175599782738 1.832311031353461e-05 2.942774568807212e-07 +Active ion transmembrane transporter activity 25 38 3.581395482733027 0.0003417638576324 16.271844660194176 41.71116504854369 1.2957221273899948 0.3267733012969381 7.788084220174416 5.097264791179653 1.6571109350293016 0.3632481416270505 0.0174905895802222 0.0199622774755299 0.02858940310823 0.0254164404521491 0.0017216429323248 +Hydrolase activity acting on glycosyl bonds 13 30 3.5352855714385742 0.0004073346899517 10.133495145631068 28.40776699029126 0.6089784953463463 0.2409908190925149 3.36301188653944 3.2424277527979313 1.935823411407979 0.3010513017078077 7.243815257670934e-07 0.0496758524768897 0.005652448648352 6.64031896522066e-05 9.056333742184927e-06 +Peptide binding 22 80 3.528975114789011 0.0004171723573542 17.133495145631066 70.30339805825243 1.21997288878307 0.3503559587509399 5.621054768990946 6.443005397350486 1.219878183292811 0.3773673755377006 2.4497639899393013e-08 0.1621145077252613 0.0563007560141117 2.666951894404368e-09 1.5150672302140797e-07 +Tetrapyrrole binding 14 18 3.492956251019408 0.0004777047649382 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 2.005336782387071e-06 0.0286799036387023 0.0001773541479557 5.447083338508773e-06 1.864182161052333e-07 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 14 34 3.478087886703888 0.0005050043178831 9.395631067961164 29.8373786407767 1.5709767518568172 0.2393367467664754 3.119976403291062 3.762391942431812 1.2135099906711824 0.3124947384976632 0.0011317679590732 0.0760657989123155 0.0130745937660514 0.0004307614542253 3.824568821206227e-05 +Steroid binding 16 23 3.475776712353127 0.0005093761976049 8.424757281553399 21.398058252427184 1.4469817519716153 0.1523451695819165 3.035656818503787 2.066091501771892 1.85140774519605 0.2395996334984524 7.605525591010176e-08 3.745017516645138e-06 4.3301861894184427e-07 2.2406308658940857e-07 3.830076963688474e-07 +Primary active transmembrane transporter activity 26 56 3.3773541918671297 0.0007318674313674 17.696601941747574 52.529126213592235 1.0080198242353189 0.3544097082146772 7.649017203625277 6.455721193615876 1.66885648871365 0.3767837436492733 0.0005224354928531 0.020861421503252 0.00643068048866 0.0026515491206924 1.836940657078699e-05 +Amide binding 31 110 3.2737686861379904 0.0010612344503051 22.521844660194176 102.53398058252426 0.8716704131409604 0.4134472412494542 7.596116055031058 7.786365397071367 1.2519470693533183 0.3815633057547212 9.968958364501306e-11 0.0032478194797668 3.240982667376524e-05 2.9583074125060726e-11 1.1281240367518084e-09 +Secondary active transmembrane transporter activity 13 19 3.1687697545754654 0.0015308561537104 9.080097087378642 21.490291262135923 1.2627683473613005 0.2947710034053126 5.466215032972134 3.0675886156990426 1.4241587428281404 0.3340388164945335 0.036407424611855 0.0691107257825923 0.2135556743224783 0.0639009119121819 0.0639136560040006 +Sterol binding 11 18 2.9823750100588384 0.0028602141130187 5.495145631067961 16.27912621359223 1.1610523788441311 0.1592175050218891 2.159304933149918 1.9111962434971217 1.7231989277496158 0.231586711794193 5.154222062755125e-05 2.685215483799648e-05 2.43078744274386e-05 0.0002102890879582 4.112388075793263e-05 +Organic acid transmembrane transporter activity 11 19 2.9777413775247585 0.0029038089481208 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 0.0116177708597984 0.0044455523824174 0.0289872856979344 0.0249977551762954 0.0054148182776431 +Protein transporter activity 6 15 2.9770102167987877 0.0029107431004171 6.053398058252427 14.696601941747574 1.6882240898296943 0.1359359142649309 2.957968193176 1.443999336657768 1.4805047019217734 0.2345897542974644 3.864028075976622e-06 0.0002365528693072 9.406788959049314e-05 1.5717931042550843e-06 0.0001380877092489 +Lipid binding 26 156 2.9683359546224515 0.0029941687764933 30.883495145631063 138.65533980582524 0.9844637598707308 0.4289871747751645 8.92748670410201 14.760635317682617 1.446857667744565 0.4068298387995807 0.0074844582074543 0.0013982202745197 0.0004230250184066 0.0068990620854652 0.0476867595756835 +Hexosyltransferase activity 21 36 2.9655164853955145 0.0030217514985186 9.633495145631068 33.87864077669903 0.7349501031127185 0.3949358882560483 4.261380470236419 4.330948695045228 1.2646745007039175 0.3422146027467064 0.0404988165441514 0.107450887051756 0.3080186048539914 0.0603040695545127 0.0012316476116813 +Lipid transporter activity 13 23 2.927119276092467 0.0034211764690883 6.546116504854369 19.805825242718445 0.7389006587243017 0.301332987440896 3.074370954053146 3.741159812966952 1.4134673193588587 0.2984913911167897 0.0013361363318055 0.0546342218360011 0.0397455353834247 0.0026746302438548 0.0011716677475313 +Endopeptidase activity 17 65 2.902160437490501 0.003705986876092 19.08495145631068 62.800970873786405 1.5604938505680932 0.2935756148549138 5.629332570724372 6.156865220927466 1.27979578418692 0.359984229645684 0.0180686721002288 0.5607731180990704 0.2226166056068401 0.0205370875184296 0.0011723818152273 +Serine hydrolase activity 10 18 2.8867710440924146 0.0038921734580394 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 0.0020695755685259 0.2106238865633207 0.0803264485176453 0.0010375816316685 0.0004353880265266 +Proton transmembrane transporter activity 13 35 2.881324504100599 0.0039600769684409 12.769417475728156 35.478155339805824 1.2352045534927034 0.2879171268332734 5.319202861157036 2.7149368379617917 1.7021108079122016 0.3308025072902738 3.676529320545375e-05 0.0056332205677222 0.0059312171066033 1.1460372499299876e-05 1.0680413577124024e-05 +Molecular transducer activity 11 34 2.877562057558247 0.0040076107593234 10.91747572815534 33.40533980582524 1.343848990749489 0.2329582295822712 4.7124072380860955 5.830391636254363 1.6098335072319665 0.2956883791113679 0.5860285032468695 0.3622182117869869 0.2470939222237589 0.4430354485331195 0.9389597210452236 +Metal ion transmembrane transporter activity 11 21 2.698448649196897 0.0069663484547748 9.563106796116504 24.67233009708738 0.8657396859235934 0.3700615753207195 4.93288923178502 4.839352380624028 1.4450904591933955 0.3424002804304004 0.6676727000160108 0.453019277017924 0.7017079055797242 0.8032303552124265 0.7143114424171995 +Peptide antigen binding 6 8 2.6699016506646966 0.0075873467132361 2.25 5.218446601941747 1.3488418251083294 0.2076946662826 1.4985834735457568 1.269832767279765 0.9581301458127084 0.2397273125927817 3.9302260156945104e-05 0.0711332726649859 0.1375212864755611 2.050947898007762e-05 2.8288826421402382e-06 +Glycolipid binding 5 9 2.658653259491652 0.0078453659153303 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 7.73433083670832e-05 0.0030581061915538 0.0005633424812776 4.060119731401367e-05 0.0001004910149917 +Alcohol binding 10 17 2.6552379877636927 0.0079252473849764 5.70873786407767 16.094660194174757 1.0972550148478282 0.1642412137618775 2.3364194162363723 2.1334758164294443 1.72577974721897 0.2306417307890987 0.0004415129315688 9.981351289840813e-05 0.0001225586688041 0.0012901179564064 0.0026180560643756 +Oxidoreduction driven active transmembrane transporter activity 12 32 2.60629134896198 0.0091528570058012 9.733009708737864 29.83252427184466 0.7626445826297276 0.3795490924215395 4.629116134249794 3.4519743101246267 1.4198222355288384 0.35536187545778 0.0291984364260669 0.0369748680428621 0.0031441363978161 0.0174389793074279 0.0001720503108284 +Cholesterol binding 9 15 2.590473834598667 0.0095843907316928 5.25 13.29126213592233 1.1679703080780182 0.1357521674166823 1.9454015982929531 1.7674569958716484 1.7544522374432017 0.2116991383290636 1.4513422065440664e-05 1.2766243381778264e-05 9.626928040323524e-06 7.247226898647767e-05 6.711779371444596e-05 +Nucleobase containing compound transmembrane transporter activity 8 12 2.589247882450802 0.0096185827575954 6.529126213592233 14.04126213592233 1.4296604886183193 0.212054291115069 3.2696940585469636 1.915888183904924 1.3255809572534116 0.2748813593420038 0.0116058691176623 0.1457663642848915 0.0036939198558231 0.0072943082509093 0.0039537733222705 +Metalloendopeptidase activity 5 14 2.576422459159446 0.00998285934326 5.449029126213592 14.364077669902912 1.4597326207035937 0.2246869419023046 2.4848715129851016 0.6671711573432166 0.9390012824303952 0.2775881383017788 0.0636918076451499 0.1499686155438198 0.0040346592713098 0.0458410907711806 0.0046379242911556 +Cargo receptor activity 3 7 2.546745979494065 0.0108732550192287 3.7063106796116503 7.95873786407767 0.9623237890522576 0.1578680760704802 1.9530058934839476 1.7914972745396005 1.6202205206532496 0.203966946010782 0.0422971632022364 1.0 0.0305060181117638 0.0300655360870906 0.0448872219881859 +Macromolecule transmembrane transporter activity 5 13 2.540228509292529 0.0110780063495417 4.820388349514563 12.281553398058252 1.6605285757306012 0.1306403746261988 2.4754663863133306 1.0160601209961664 1.3599823000893485 0.2280235038874096 0.000180875306022 0.0042324529563037 0.0009244711113057 9.57968350367248e-05 0.000277756887713 +Antigen binding 6 10 2.538099233854826 0.0111456375974761 2.504854368932039 6.936893203883495 1.1926555941065955 0.2669458193807861 1.6287691845260013 1.3674077446215156 0.9067202373946956 0.2605304200525402 0.0003664619465316 0.1070183553885475 0.2030300441679912 0.0001958127697586 7.666164058302006e-05 +Glycosyltransferase activity 25 51 2.51568736624682 0.011880051209461 10.808252427184469 46.75 0.6230735361107147 0.5000303532444054 4.489970468729936 5.6981622825309435 0.9932734853426128 0.358363386747457 0.0775877007042334 0.0427934356613144 0.2047370877292106 0.0946318432858537 0.0105527321942639 +Protein transmembrane transporter activity 4 12 2.506721687656555 0.0121856617070656 4.37621359223301 11.264563106796116 1.6409152716253632 0.1284874270119089 2.3258190399954897 0.995332092405782 1.387057072324357 0.2266762256512647 7.73433083670832e-05 0.0030581061915538 0.0005633424812776 4.060119731401367e-05 0.0010145405611514 +Udp glycosyltransferase activity 10 17 2.5028592485035737 0.012319452649284 5.111650485436893 16.645631067961165 0.3599735227181602 0.3819150449260511 2.50187506268716 3.5246228662547776 1.2344018614792536 0.2994506580113357 0.1575784846739738 0.3092959809067388 0.523802502209471 0.2770823582814727 0.0716032196730593 +Quaternary ammonium group binding 3 11 2.4750051872072967 0.0133234240717834 2.8567961165048543 12.12864077669903 0.9707568143407772 0.2573327609820879 1.4849985868988949 1.260087490061347 1.304146106648176 0.2795917987269193 0.0029371281125028 0.0051137089586154 5.563842498563775e-05 0.0017956484300789 0.0201372619620155 +Electron transfer activity 18 54 2.461948709285275 0.0138184426457401 14.919902912621358 52.12621359223301 0.5312195787834075 0.4459804256520286 6.65997259318913 4.498499451328372 1.405540355221493 0.3721784721862224 0.0068186428070254 0.086158736226278 0.0029612996216462 0.0111193401215375 2.3519029807808334e-05 +Symporter activity 6 9 2.402164361327286 0.0162983835536498 3.638349514563106 9.1747572815534 0.9770544165414302 0.3122690599192905 2.3735568316725377 2.065327188945721 1.1044541290009051 0.3081067804681572 0.0338120513630788 0.1948770046367652 0.3524722176470324 0.0918272438847456 0.1644709145443467 +Monooxygenase activity 6 10 2.3752972725468013 0.0175348217127782 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 0.0008023159172073 0.1244478155008913 0.0022569298755563 0.0004337635961428 0.000234374088003 +Peptidase activity 35 117 2.36410525151997 0.0180736770240905 29.021844660194176 113.626213592233 1.2572335980018865 0.3731282983707893 8.334453494010912 9.805689463637474 1.5136028692995414 0.3922229485757941 0.007903157498163 0.4216272350419118 0.321653467227701 0.0124064592640607 0.0009972273083501 +Organophosphate ester transmembrane transporter activity 6 10 2.354978628518225 0.0185237710203953 5.665048543689321 12.143203883495143 1.4298365636921646 0.2056324024803549 3.029697948284232 1.927415248708952 1.2819429632405106 0.2680490563295835 0.0029371281125028 0.1026081339138497 0.001231210484404 0.0017956484300789 0.0035298468720628 +Nucleotide transmembrane transporter activity 6 10 2.354978628518225 0.0185237710203953 5.606796116504855 12.029126213592232 1.4217258291760082 0.2036087501116975 3.0234925518113496 1.8899648667798992 1.291115513359647 0.2666064512499804 0.0024564584457719 0.0981765691424607 0.0010709052035729 0.0014975917181939 0.0028394369313259 +Hexosaminidase activity 3 5 2.331395597661201 0.0197325094562981 2.5194174757281553 4.973300970873787 0.3568105957806153 0.2227497456156347 1.091499214132507 0.3065083294438748 1.6445593916296413 0.2548912926080147 6.741537110755754e-05 1.0 0.0032780640178306 0.0010839430889874 0.0005732271800539 +Signal sequence binding 5 29 2.3108810848728902 0.0208394241171265 5.560679611650485 26.50242718446602 0.435828138514089 0.5798441286349703 3.257360227950366 2.1761045475756564 0.8353222176818301 0.3288364338889158 0.0007801778634092 0.1788224008957527 0.0583817580096799 0.0003819251815083 0.0120719478590556 +Ceramide binding 4 5 2.306044939357846 0.0211081214066237 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 0.0003500834863265 3.066034551708988e-05 5.820213408235142e-06 0.0002086676392486 0.0002481332774246 +Phosphatidylcholine binding 2 7 2.300634700441199 0.0214122879125013 2.2524271844660193 7.929611650485437 1.2697801287388335 0.1567893034984199 1.081337239384838 1.04388968498945 1.4953842980517238 0.2256102823610289 0.0092378701630156 0.0027067874988798 0.0004672463302539 0.0063676045893722 0.039942155971048 +Antiporter activity 6 8 2.3003511985304645 0.0214283312494398 4.621359223300971 10.405339805825244 1.056576117278179 0.2813324268221227 2.679901841610502 1.304685592846984 1.2558310293487471 0.3063102364368053 0.2978493425719649 0.1747599807978781 0.3196260593385788 0.2464598217650195 0.1196653936274396 +Solute cation symporter activity 5 7 2.2446909716865218 0.0247879780374686 2.854368932038835 7.206310679611651 0.8639239563858236 0.3319920905256767 1.9640347167867271 2.0653542869596597 1.117186698589392 0.3146562336443082 0.0636918076451499 0.1499686155438198 0.2780273254227372 0.0458410907711806 0.2151867556135544 +Fad binding 5 13 2.2168573375341576 0.0266328418865813 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 0.0349575779036428 0.1201219647894398 0.2263045436956677 0.0247234076565489 0.0012863968531589 +Calcium ion binding 31 91 2.208440823985023 0.0272135586400623 21.00485436893204 81.67961165048544 0.6464856503310022 0.4940276647939897 7.408010340962093 8.52860815905726 1.2261945166831902 0.3858741960292539 0.153515017213681 0.7485560273761018 0.2883767829739856 0.140903333072204 0.0500561817803642 +Carbohydrate derivative transmembrane transporter activity 6 9 2.183372104040389 0.0290084185483792 4.672330097087379 10.12135922330097 1.0096229459917263 0.2944050311743799 2.686158589641687 1.471354338494036 1.2935479322863277 0.3146313980204608 0.1636169873806569 1.0 0.2263045436956677 0.1318172807011351 0.1303826157459173 +Abc type transporter activity 6 10 2.1795958529752992 0.0292874324818326 3.0194174757281553 7.652912621359223 0.9831250219385844 0.2361571806590424 1.9482657586917436 2.350049836723345 1.2743804993059251 0.258194993176919 0.0005527262873498 0.1157751708195439 0.2186221342412543 0.002932051876052 0.0063149437065281 +Serine type exopeptidase activity 5 7 2.171643384843334 0.0298825719260393 3.783980582524272 6.997572815533981 1.020609253431403 0.1137432544246352 1.3363606860118669 0.0492066381861973 1.87035730934538 0.1990592265121372 6.741537110755754e-05 0.0432957136582515 0.0849171013653387 3.972711663948022e-05 2.858966188275996e-05 +Iron ion binding 10 25 2.1248599145878364 0.0335983036396629 6.524271844660194 22.196601941747577 0.9076096695164306 0.382669917893863 2.4429198675966717 3.289094676807881 0.9378690899634522 0.3126784916965753 0.0905813840099169 0.2597451867723493 0.1202677732034906 0.0614665248433369 0.0001478886096126 +Vitamin transmembrane transporter activity 3 5 2.1193445046250576 0.0340613630947843 2.7766990291262137 6.252427184466019 1.4438342367310928 0.182339474606115 1.52603324115363 1.3650879028699858 1.0282691527982806 0.2346378729908682 0.0016623787157526 0.0038211367015083 0.0146091852998709 0.0104402688493973 0.0119688845689888 +Sphingolipid binding 5 7 2.108774063922308 0.0349640883430331 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 0.0013416268925549 8.597904339497348e-05 2.398682396472892e-05 0.0008110696558398 0.0013491401517078 +Oxidoreductase activity 71 243 2.103065870053284 0.0354600119018186 52.54126213592233 227.42961165048544 0.490492706528076 0.5955656171597654 20.033606385640603 16.688970744458114 1.2909283370539455 0.4039853598071011 4.1657021404016594e-07 0.0004422470781275 7.055762904255473e-07 4.869005061864318e-06 4.855197518402948e-10 +Tap binding 4 6 2.101070489450944 0.0356347789593824 1.8592233009708736 3.895631067961165 0.8127354819395453 0.3477955376218754 1.070154411615344 1.0456940556701602 1.051123567423606 0.2887299843781864 0.0006958331158308 1.0 1.0 0.0004683577123997 5.170697431969709e-06 +Purine nucleotide transmembrane transporter activity 5 8 2.089215266485224 0.0366883497889309 4.334951456310679 9.441747572815531 0.9917737457277228 0.2833655940290197 2.4104227054611673 1.6217588601139772 1.262135146193827 0.3001583617421954 0.0722227703866111 1.0 0.1459927402947744 0.0569248849368824 0.039942155971048 +Sterol transporter activity 6 10 2.0520583109786883 0.0401639958269131 2.621359223300971 8.364077669902912 0.5454888897585024 0.2973249899153176 1.425267849835305 1.6080715320593837 1.318674977748992 0.2709274408896192 0.0253098881196153 0.0055832614279084 0.0210734332562196 0.017764157863851 0.0043329575683166 +Serine type carboxypeptidase activity 4 5 2.011504991945769 0.0442721435759225 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 0.0002072945122892 0.0242848323540905 0.0480955538847994 0.0001387808195727 2.661109756617399e-05 +Amino acid transmembrane transporter activity 6 9 2.009316416753593 0.0445035879750765 4.325242718446602 10.521844660194176 0.9562493229862624 0.2921494362491497 2.574340086864074 1.34633933573134 1.106576767449958 0.2884960270895668 0.6789681787500395 0.1788224008957527 0.3263246311566628 0.6287574181217924 0.3081896593873433 +Oxidoreductase activity acting on a heme group of donors 4 7 2.000096154155932 0.0454898819830444 3.111650485436894 6.483009708737864 0.8850005512180296 0.2757097651603665 1.538237610319269 1.0226572421183926 1.2777814224392188 0.2966482201944345 0.0643496578587389 0.0711332726649859 0.1375212864755611 0.0506052248933858 0.0049176108076387 +Sodium channel regulator activity 2 9 1.9943759550979865 0.0461109842053184 1.2742718446601942 3.6966019417475726 0.3480048328963068 0.4818068972424751 1.0072640073334362 1.4951988232878188 1.029255998785111 0.3156490188407561 0.0076621340630544 1.0 1.0 0.0052676758380378 0.0336357980244025 +Voltage gated anion channel activity 4 6 1.9867054979812009 0.0469550422013109 2.854368932038835 6.25 1.127126362633441 0.1649553590552043 1.5417035527207152 0.9966570336472054 1.4583344406160936 0.2334940994157564 0.0022412273106297 0.0010343090391069 0.004071454093033 0.0015206572897169 0.000918782674844 +Mirna binding 5 15 1.965766738489353 0.0493255616038601 5.356796116504855 13.716019417475728 0.2051470497500039 0.5875839080603199 2.9289942319606412 1.5748125731018472 0.8441668576388831 0.3077891504368221 0.2144776286214526 1.0 1.0 0.5358758009484922 0.0159032502878613 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..51ca3ebee17ac35a09c2edee5191b8cf780f8fc2 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 1395, + "title": "Average number of proteins per term", + "value": 17.585663082437275 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a24bf5d93ca6735a9ab4a5a8d37f7a6b89e2f25d --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..18b45cda9a48693c8d2899af759c837132dc6766 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,444 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter activity 0.6004199218784377 6.587536831757315 4.471830748321565e-11 6.238203838972121e-08 6.238204033408583e-08 173 P30536,P61916,Q9NS69,P21796,P51798,Q7KZN9,Q9UBX3,P45880,Q70HW3,O95168,O60830,O43676,Q9H0U3,Q9C0H2,Q14849,Q9Y6M7,P00403,Q9UGP8,P04062,Q9HD20,Q96ES6,L0R6Q1,Q96SU4,Q99567,Q9Y619,Q9H2V7,O75964,Q9H2D1,P28288,O43681,Q8TB61,Q9BSK2,Q6NUK1,P17900,P55011,O43808,P03886,Q9UDW1,Q99595,Q9BXP2,Q6P4Q7,O15173,P05023,O96000,O15118,Q07820,Q9Y584,Q14728,P38435,P24539,Q13423,Q9UM00,Q9BQT8,Q9P0J0,P08183,Q4KMQ2,P11166,Q8WTV0,P06576,O75438,Q9Y487,Q9UJS0,Q96GC9,Q15043,O75746,Q9Y5J9,O14925,Q03519,Q00325,P12235,Q03518,Q93050,Q6P4A7,O14678,P16615,P53985,Q99797,P51991,P08574,Q9Y277,P22059,Q9Y6M9,P13073,P14854,P20020,P51970,P30825,O95202,Q96NB2,O75306,P12236,O14975,Q8NE01,Q9BZF1,O43772,Q9NUT2 96 +Ion transmembrane transporter activity 0.5680396813447324 4.924038332162267 8.477621878946214e-07 0.0011819297236156 0.0005913141260571 95 P20020,P21796,P24539,P51798,Q9UBX3,Q7KZN9,P45880,Q70HW3,P16615,Q13423,Q9UM00,P53985,P30825,O95202,Q9H0U3,Q9C0H2,Q96NB2,Q9Y6M7,P00403,Q9BQT8,P12236,Q9HD20,Q4KMQ2,Q96ES6,P11166,P06576,P08574,Q9Y619,Q9Y487,O75964,Q9H2D1,Q9UJS0,O43681,Q9Y277,Q8TB61,Q15043,Q6NUK1,O75746,P55011,O43808,Q9UDW1,P13073,Q9BXP2,Q6P4Q7,Q00325,P12235,O43772,Q93050,P05023,Q6P4A7,P14854,Q14728 52 +Active transmembrane transporter activity 0.5726349185595757 4.474345510373875 7.664571925358743e-06 0.0106351612884614 0.0026730194589692 74 P20020,P51970,O14678,P51798,Q7KZN9,Q9UBX3,P16615,P53985,O95168,O95202,O43676,Q9Y6M7,P00403,Q9P0J0,O75306,P08183,P12236,Q9HD20,Q96ES6,P08574,P28288,Q15043,Q9Y6M9,P55011,P03886,Q9UDW1,P13073,Q9BXP2,Q03519,Q00325,P12235,Q03518,P05023,P14854,Q9NUT2 35 +Cation transmembrane transporter activity 0.5838206754120127 4.193166792353779 2.750870274170758e-05 0.0376481706013656 0.0054820914749547 65 P20020,P24539,Q7KZN9,P16615,Q70HW3,Q13423,P30825,O95202,Q9H0U3,Q96NB2,Q9Y6M7,P00403,Q4KMQ2,Q9HD20,Q96ES6,P08574,Q9Y619,Q9Y487,O75964,Q15043,P55011,O43808,Q9UDW1,P13073,Q9BXP2,Q00325,P12235,O43772,Q6P4Q7,Q93050,P14854 31 +Anion transmembrane transporter activity 0.605630471557749 3.9238519635325937 8.714429617828756e-05 0.1144723441826905 0.0069436585050428 43 P21796,P51798,Q9UBX3,P45880,P53985,P30825,Q9C0H2,Q96NB2,Q9Y6M7,Q9BQT8,P12236,Q4KMQ2,P11166,Q9Y619,Q9H2D1,Q9UJS0,O43681,Q9Y277,Q8TB61,Q15043,Q6NUK1,O75746,P55011,O43808,Q9BXP2,P12235,Q14728 27 +Inorganic molecular entity transmembrane transporter activity 0.5361714667784021 3.923579200454299 8.724306634078083e-05 0.1145943582916258 0.0069436585050428 71 P20020,P21796,P24539,P51798,Q7KZN9,Q9UBX3,P16615,P45880,Q13423,O95202,Q9H0U3,Q9C0H2,Q9Y6M7,P00403,Q99797,Q4KMQ2,Q9HD20,Q96ES6,P08574,Q9Y487,O75964,O43681,Q9Y277,Q15043,P55011,Q9UDW1,P13073,Q9BXP2,Q00325,P12235,Q6P4Q7,Q93050,P14854 33 +Organic anion transmembrane transporter activity 0.7053212210259269 3.619134776706773 0.0002955896682952 0.3379462560508531 0.0077801431560727 28 Q6NUK1,O75746,P12236,Q02978,O43808,P11166,Q9UBX3,Q9Y619,P53985,Q9H2D1,Q9UJS0,P30825,Q8TB61,P12235,Q96NB2,Q9Y6M7,Q9BQT8,Q14728 18 +Hydrolase activity hydrolyzing o glycosyl compounds 0.763221013190764 3.5944270876953843 0.0003251061704865 0.3646611786051335 0.0078434299685026 23 P17900,O60476,Q9BTY2,P16278,P06865,P06280,O60502,P54802,P10253,P08236,Q9NUJ1,P04062 12 +Active ion transmembrane transporter activity 0.6133267416823356 3.581395482733027 0.0003417638576324 0.3792594447251351 0.0078434299685026 38 P20020,P51798,Q7KZN9,P16615,O95202,P31930,Q9Y6M7,P00403,P12236,Q9HD20,Q96ES6,P08574,P06576,P23634,Q15043,Q02978,P55011,Q9UDW1,P13073,Q9BXP2,Q00325,P12235,P05023,P05141,P14854 25 +Hydrolase activity acting on glycosyl bonds 0.667208632157096 3.5352855714385742 0.0004073346899517 0.4335393452799914 0.0084076826497003 30 P17900,O60476,Q9BTY2,P16278,O75503,P06865,P06280,O60502,P54802,P10253,P08236,Q9NUJ1,P04062 13 +Peptide binding 0.467828750254264 3.528975114789011 0.0004171723573542 0.4412632573521792 0.0084076826497003 80 P24390,Q9UIQ6,P10321,O00264,Q15392,O14773,Q8WTV0,Q9NZ08,Q9Y287,P42892,O60684,Q92973,Q03519,Q03518,Q9BYT8,O43731,Q9NQX7,P55899,P01889,P04439,P52294,Q9Y584 22 +Tetrapyrrole binding 0.8131794101535983 3.492956251019408 0.0004777047649382 0.486526762393521 0.0090053803660656 18 Q8WUJ1,O15173,P53701,P08574,P30519,O43169,O00264,Q9Y5Z4,Q16850,Q9H7Z7,Q99707,Q96EY8,P09601,Q6UW02 14 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.6303233490876254 3.4780878867038876 0.0005050043178831 0.5057228893501071 0.009218882492508 34 Q32P28,Q9NVH6,Q14534,P16435,Q15800,P30519,O15460,Q16850,O75845,Q8NB78,P13674,P09601,O60568,Q6UW02 14 +Steroid binding 0.7448057276686327 3.475776712353127 0.0005093761976049 0.5087297195815453 0.009218882492508 23 P30536,O15173,Q9BZF1,P61916,P38435,P21796,Q96SU4,O00264,P45880,O15118,P35610,P22059,O75477,Q14849,Q14108,P04062 16 +Primary active transmembrane transporter activity 0.5233885370583014 3.3773541918671297 0.0007318674313674 0.6398839185458307 0.0115655519267554 56 P20020,P51970,O14678,P51798,Q7KZN9,P16615,O95168,O43676,P00403,Q9P0J0,O75306,P08183,Q9HD20,P08574,P06576,P28288,Q9Y6M9,P03886,Q9UDW1,P13073,Q03519,Q03518,P05023,O96000,P14854,Q9NUT2 26 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen 0.9830805134189028 3.3362259427928493 0.0008492411343357 0.6943133470674323 0.011966579620185 2 P30519 1 +Er retention sequence binding 0.9719953325554233 3.287749083624196 0.0010099180613525 0.7557462363645749 0.0134174828151122 2 P24390 1 +Amide binding 0.4325227580963892 3.2737686861379904 0.0010612344503051 0.7726371664376838 0.013966245831846 110 P24390,Q9UIQ6,P21796,P10321,P45880,O00264,Q15392,O14773,P07602,Q8WTV0,Q9UM22,Q9Y680,Q9NZ08,Q9Y287,P42892,O60684,P00374,Q9NZJ7,Q92973,Q03519,Q03518,Q9BYT8,O43731,Q9NQX7,Q96AY3,P55899,P01889,P04439,P52294,Q9Y584,P35610 31 +Phospholipase d activity 0.9652858809801615 3.2582714634772905 0.0011209312204973 0.790823337221706 0.0140043468857941 2 P09601 1 +Vitamin d binding 0.9603267211201836 3.236417069394874 0.0012104039143059 0.815394871841332 0.0148115215829542 2 P04062 1 +Sulfotransferase activity 0.9582847141190202 3.227401676714224 0.0012491996458676 0.8251318227685697 0.0151042556405374 2 Q7LGA3 1 +Lysophosphatidic acid binding 0.953033838973158 3.2041748014664533 0.0013545021201188 0.8490507061388064 0.015654859131926 2 P50897 1 +Sulfatide binding 0.953033838973158 3.2041748014664533 0.0013545021201188 0.8490507061388064 0.015654859131926 2 P50897 1 +Ion gated channel activity 0.9527421236872768 3.202882538731034 0.0013605946373882 0.8503299262914983 0.015654859131926 2 Q9C0H2 1 +Intracellular calcium activated chloride channel activity 0.9527421236872768 3.202882538731034 0.0013605946373882 0.8503299262914983 0.015654859131926 2 Q9C0H2 1 +Secondary active transmembrane transporter activity 0.7364373883972638 3.1687697545754654 0.0015308561537104 0.8820129740535056 0.0162985164272841 19 P12236,Q02978,Q96ES6,P55011,P51798,Q9UBX3,P53985,Q9BXP2,O95202,Q00325,P12235,Q9Y6M7,Q15043 13 +Transition metal ion transmembrane transporter activity 0.944574095682609 3.1666184538812963 0.0015422252103236 0.8838723022777322 0.0162985164272841 2 Q9HD20 1 +Manganese ion transmembrane transporter activity 0.944574095682609 3.1666184538812963 0.0015422252103236 0.8838723022777322 0.0162985164272841 2 Q9HD20 1 +Beta 2 microglobulin binding 0.9291131855309176 3.0975457257619063 0.0019513029053814 0.9344358877485184 0.0191946791693617 2 P55899 1 +Phospholipase a1 activity 0.9232788798132968 3.0713329901715167 0.0021310534376393 0.9490031631949056 0.0200433417482671 2 Q8NCC3 1 +Galactoside binding 0.9200700116686042 3.0568812705975854 0.0022365284505856 0.9559949701087624 0.0201287560552707 2 P16278 1 +Galactosidase activity 0.9200700116686042 3.0568812705975854 0.0022365284505856 0.9559949701087624 0.0201287560552707 2 P16278 1 +C palmitoyltransferase activity 0.9130688448074676 3.025264332820241 0.0024841591495903 0.9688740518008476 0.0216587625854906 2 O15269 1 +5 3 exodeoxyribonuclease activity 0.9110268378062952 3.016020454127517 0.0025611598244719 0.9720517602833908 0.0221914158704243 2 Q8IV08 1 +Sterol binding 0.7276222334183936 2.9823750100588384 0.0028602141130187 0.9816057233949356 0.0242881978851596 18 P30536,Q9BZF1,P61916,P21796,Q96SU4,P45880,O15118,P35610,P22059,Q14849,Q14108 11 +Organic acid transmembrane transporter activity 0.7060585619426132 2.9777413775247585 0.0029038089481208 0.982694073905705 0.0242881978851596 19 O75746,P08183,O14975,Q9UBX3,Q9Y619,P53985,Q9H2D1,Q9UJS0,P30825,Q96NB2,Q9BQT8 11 +Protein transporter activity 0.7867330407747781 2.9770102167987873 0.0029107431004171 0.9828611529427284 0.0242881978851596 15 Q9Y5J9,Q9HD20,Q9NS69,Q99595,O60830,Q9Y584 6 +Lipid binding 0.3867940818460953 2.9683359546224515 0.0029941687764933 0.9847493182694212 0.0242881978851596 156 Q9BQE5,P30536,P21796,P38435,O00560,P45880,O00264,P50897,P04083,Q14849,O15254,P04062,O14773,P07602,Q8WTV0,Q9UM22,Q14108,P22059,A6NIH7,Q15067,O43292,Q96L92,Q8NCC3,O15173,O15118,P35610 26 +Hexosyltransferase activity 0.5569062599304672 2.9655164853955145 0.0030217514985186 0.9853266896763696 0.0242881978851596 36 P46976,P06865,O60512,P04062,Q2TAA5,Q8N4A0,P46977,Q10472,Q96L58,O43909,O60762,Q6ZXV5,Q04446,Q9BT22,P04844,Q8TCJ2,Q13126,Q8NAT1,P04843,O43505,O60568 21 +Lipid transporter activity 0.6627119422192949 2.927119276092467 0.0034211764690883 0.9916100749773378 0.0269635094597641 23 P08183,P30536,Q4KMQ2,P17900,O14678,Q9BZF1,P61916,O14975,Q96SU4,O15118,Q14849,P22059,Q96GC9 13 +Endopeptidase activity 0.4674573748645731 2.902160437490501 0.003705986876092 0.9943689262043932 0.0285367629258084 65 Q8TCT9,Q99797,O14773,O75844,Q10713,Q2T9J0,O43292,P42892,P28072,P67812,P49721,Q4J6C6,Q5JRX3,Q6P179,Q9NZ08,Q9BYT8,Q96K76 17 +Serine hydrolase activity 0.7121385828360983 2.8867710440924146 0.0038921734580394 0.9956612800174988 0.0291490770921229 18 Q2T9J0,O14773,P10619,Q9HB40,Q9H3G5,P67812,P42785,Q4J6C6,Q5JRX3,O75976 10 +L ornithine transmembrane transporter activity 0.882438739789954 2.8855391168084776 0.003907439008048 0.9957530522255832 0.0291490770921229 2 Q9Y619 1 +Proton transmembrane transporter activity 0.5532584565930796 2.881324504100599 0.0039600769684409 0.9960548751439317 0.0293036423507562 35 Q96ES6,P24539,P08574,Q9UDW1,Q9Y487,O75964,P14854,Q13423,P13073,Q00325,P12235,Q93050,P00403 13 +Molecular transducer activity 0.558493613410473 2.877562057558247 0.0040076107593234 0.9963089693025896 0.0293036423507562 34 P30536,O15173,O14786,Q8WTV0,Q9BUN8,O15118,Q15629,Q9Y6I9,Q99720,Q14108,Q9UGP8 11 +Sphingosine n acyltransferase activity 0.8544340723453793 2.7557607756431652 0.0058555806363989 0.9997232911030188 0.0394615216800795 2 Q96G23 1 +Voltage gated chloride channel activity 0.847432905484236 2.7230087557784564 0.0064690343355555 0.9998830329935302 0.0423676192399061 2 Q4KMQ2 1 +Metal ion transmembrane transporter activity 0.6469494111500594 2.698448649196897 0.0069663484547748 0.999941825521241 0.0447836686378382 21 P20020,Q9HD20,P55011,P05023,P16615,Q9BXP2,O95202,Q6P4Q7,Q9H0U3,Q9Y6M7,Q15043 11 +Mannosyl oligosaccharide mannosidase activity 0.8398483080513316 2.687387489302366 0.0072013358314906 0.9999581830962214 0.0454563958594091 2 O60476 1 +Peptide antigen binding 0.8560697843628299 2.6699016506646966 0.0075873467132361 0.9999756920352862 0.047041549622064 8 P55899,P01889,P04439,Q03519,Q15392,Q03518 6 +Glycolipid binding 0.8370129192183023 2.658653259491652 0.0078453659153303 0.9999830872415478 0.0480012519819555 9 O43292,O14773,P07602,Q9UM22,P50897 5 +Alcohol binding 0.6940207192327074 2.6552379877636927 0.0079252473849764 0.99998488408829 0.0482782537207081 17 P30536,Q9BZF1,P61916,P21796,Q14108,P45880,O15118,O75477,Q14849,P35610 10 +Solute proton symporter activity 0.9210802354280326 2.6504325827975244 0.0080388769274011 0.9999871163471116 0.0487575361466285 3 Q96ES6 1 +Solute sodium symporter activity 0.831096849474912 2.646104524819264 0.0081424652275732 0.9999888629774112 0.0489757820415807 2 Q9Y6M7 1 +Sodium channel inhibitor activity 0.920047472661356 2.6459960690826025 0.0081450762965209 0.9999889038014274 0.0489757820415807 3 P46934 1 +Cation chloride symporter activity 0.8264294049008157 2.624007182157026 0.0086901952624562 0.999994846345126 0.0515864782601128 2 P55011 1 +Potassium chloride symporter activity 0.8264294049008157 2.624007182157026 0.0086901952624562 0.999994846345126 0.0515864782601128 2 P55011 1 +Magnesium ion transmembrane transporter activity 0.8255542590431739 2.6198577414877855 0.0087966454092429 0.9999955633554448 0.05199712010972 2 Q9H0U3 1 +Oxidoreduction driven active transmembrane transporter activity 0.5373382620482664 2.60629134896198 0.0091528570058012 0.999997312844766 0.0536480484163561 32 O75306,P51970,Q9Y6M9,P03886,P08574,Q9UDW1,Q7KZN9,P14854,P13073,O43676,P00403,Q9P0J0 12 +Aspartic endopeptidase activity intramembrane cleaving 0.8223453908984759 2.6046263870889335 0.0091974492016406 0.9999974763634136 0.0536838562187813 2 Q8TCT9 1 +Dolichyl phosphate mannose protein mannosyltransferase activity 0.820595099183185 2.596307281665431 0.0094231750928772 0.9999981635137892 0.054614264590179 2 Q6ZXV5 1 +Neurexin family protein binding 0.8203033838973073 2.594920002312192 0.0094612937490823 0.9999982595013188 0.054614264590179 2 O00560 1 +Cholesterol binding 0.71913314871282 2.590473834598667 0.0095843907316928 0.9999985365445409 0.054614264590179 15 P30536,Q9BZF1,P61916,P21796,Q14108,P45880,O15118,Q14849,P35610 9 +Nucleobase containing compound transmembrane transporter activity 0.7711104561813084 2.589247882450802 0.0096185827575954 0.9999986053547166 0.054614264590179 12 Q6NUK1,P12236,P51991,L0R6Q1,Q9H2D1,Q8TB61,P12235,Q9BSK2 8 +Metalloendopeptidase activity 0.7338611610025919 2.576422459159446 0.00998285934326 0.9999991651935882 0.0553118255815041 14 O75844,Q99797,Q10713,P42892,Q5JRX3 5 +Ribosomal protein s6 kinase activity 0.8159276546091014 2.574084676755129 0.0100505672205344 0.9999992411594392 0.0553118255815041 2 Q15418 1 +Ganglioside binding 0.903122264371158 2.5729699907401606 0.0100829950021612 0.9999992750556336 0.0553118255815041 3 Q9UM22,P07602 2 +Glycosphingolipid binding 0.903122264371158 2.5729699907401606 0.0100829950021612 0.9999992750556336 0.0553118255815041 3 Q9UM22,P07602 2 +Organic hydroxy compound transmembrane transporter activity 0.8138856476079248 2.564344744034034 0.010337081438434 0.999999493265068 0.056109838936247 2 P53985 1 +Cargo receptor activity 0.8842884080866196 2.5467459794940654 0.0108732550192287 0.9999997620623658 0.0583391951993235 7 Q8WTV0,O15260,Q14108 3 +Macromolecule transmembrane transporter activity 0.7440659731616466 2.540228509292529 0.0110780063495417 0.9999998217457766 0.0587597675194322 13 Q9NS69,O14925,Q99595,O60830,Q9Y584 5 +Antigen binding 0.796042500515583 2.538099233854826 0.0111456375974761 0.999999837966188 0.0588945623048453 10 P55899,P01889,P04439,Q03519,Q15392,Q03518 6 +Glycosyltransferase activity 0.4500322008888033 2.51568736624682 0.011880051209461 0.9999999425241056 0.0620699304763974 51 P46976,P06865,O60512,P04062,Q2TAA5,P43490,Q8N4A0,P46977,Q7Z2W4,Q10472,Q96L58,O43909,Q06203,Q9H974,O60762,Q6ZXV5,Q04446,Q9BT22,P04844,Q8TCJ2,Q13126,Q8NAT1,P04843,O43505,O60568 25 +Xenobiotic transmembrane transporter activity 0.8019253208867982 2.5070818070348344 0.0121732534012366 0.999999962008229 0.0629592521531727 2 P08183 1 +Protein transmembrane transporter activity 0.7557842272600384 2.506721687656555 0.0121856617070656 0.9999999626681604 0.0629592521531727 12 O60830,Q9Y584,Q99595,Q9NS69 4 +Udp glycosyltransferase activity 0.6695052957070224 2.5028592485035737 0.012319452649284 0.9999999690957708 0.0634156326411484 17 P46976,Q10472,Q8N4A0,Q96L58,P06865,O60512,Q8NAT1,O43909,O43505,O60568 10 +Ubiquinone binding 0.7960910151691976 2.479015377980418 0.0131745625913513 0.9999999907685824 0.0673205670876742 2 Q16134 1 +Quaternary ammonium group binding 0.767048727464578 2.4750051872072967 0.0133234240717834 0.9999999925205248 0.0675860966550469 11 P21796,A1L0T0,P45880 3 +Electron transfer activity 0.4425279324686622 2.461948709285275 0.0138184426457401 0.999999996285993 0.0695910739740344 54 O75306,P14406,P51970,Q9Y6M9,P16435,P03886,P08574,P05091,Q9UDW1,Q7KZN9,O15460,P14854,O95168,P13073,O43676,P23378,P00403,Q9P0J0 18 +Triglyceride lipase activity 0.7826721120186735 2.4141306110093455 0.0157728071550744 0.9999999997666396 0.0774755844412988 2 Q8NCG7 1 +Oxidative phosphorylation uncoupler activity 0.781505250875129 2.4084665900783695 0.0160196924764965 0.9999999998355484 0.0781380105059886 2 P12235 1 +Nucleobase transmembrane transporter activity 0.781505250875129 2.4084665900783695 0.0160196924764965 0.9999999998355484 0.0781380105059886 2 P12235 1 +Symporter activity 0.7854018632151593 2.402164361327286 0.0162983835536498 0.99999999988923 0.0792203660534549 9 P55011,Q96ES6,P53985,Q00325,Q9Y6M7,Q15043 6 +Mhc class ib protein binding 0.8634374088123615 2.39937437182575 0.0164231141931947 0.9999999999071892 0.0795494593732871 3 Q03518,Q03519 2 +Phosphatidyl phospholipase b activity 0.8624724703781195 2.395111929370207 0.0166152922844111 0.9999999999293336 0.0795914112100007 3 Q8NCC3 1 +Catalytic activity acting on a glycoprotein 0.7782963827304472 2.3928725020222292 0.0167170490928532 0.9999999999388326 0.0795914112100007 2 Q96L58 1 +Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity 0.7782963827304472 2.3928725020222292 0.0167170490928532 0.9999999999388326 0.0795914112100007 2 Q96L58 1 +Beta 1 3 galactosyltransferase activity 0.7782963827304472 2.3928725020222292 0.0167170490928532 0.9999999999388326 0.0795914112100007 2 Q96L58 1 +Heme transmembrane transporter activity 0.7762543757292675 2.3829352275078266 0.0171752160389537 0.999999999968073 0.0809440080214206 2 O15173 1 +Monooxygenase activity 0.7643902721640079 2.3752972725468013 0.0175348217127782 0.9999999999808376 0.0823605262266855 10 P30519,Q16850,Q15800,Q14534,P09601,Q6UW02 6 +Neurotrophin binding 0.7739206534422431 2.3715652403270906 0.0177129192864728 0.9999999999851196 0.0829178604182204 2 Q99523 1 +Peptidase activity 0.3691558101069016 2.36410525151997 0.0180736770240905 0.999999999991086 0.0840425981620211 117 Q96DE0,Q14674,Q9UIQ6,O95630,P49721,Q13107,Q6P179,Q96FZ2,Q9H4L4,O75844,Q8TCT9,O14773,Q99797,Q10713,Q9HB40,P67812,Q92820,P20618,Q9NZ08,O75976,Q2T9J0,O43292,P42892,P55786,P28072,Q9H3G5,P42785,Q5JRX3,Q6NTF9,Q9BYT8,Q92542,P10619,Q4J6C6,O76031,Q96K76 35 +H4 histone acetyltransferase activity 0.8535591312585797 2.355645887295107 0.0184905348498343 0.9999999999950704 0.0852827081632064 3 Q86UY6 1 +Organophosphate ester transmembrane transporter activity 0.7604782636299847 2.3549786285182255 0.0185237710203953 0.9999999999952978 0.0852827081632064 10 Q6NUK1,P12236,Q9H2D1,Q8TB61,P12235,Q9BSK2 6 +Nucleotide transmembrane transporter activity 0.7604782636299847 2.3549786285182255 0.0185237710203953 0.9999999999952978 0.0852827081632064 10 Q6NUK1,P12236,Q9H2D1,Q8TB61,P12235,Q9BSK2 6 +Fatty acid synthase activity 0.768669778296386 2.345931711440025 0.0189795844812734 0.9999999999975404 0.0862427373009005 2 Q9NWU1 1 +Hexosaminidase activity 0.9096771831227638 2.3313955976612015 0.0197325094562981 0.9999999999991572 0.0888176121009258 5 P17900,O60502,P54802 3 +Signal sequence binding 0.5245300464322 2.3108810848728902 0.0208394241171265 0.9999999999998256 0.0925827918579349 29 O43731,O60684,P24390,P52294,Q9Y584 5 +Ceramide binding 0.9036496350364808 2.306044939357846 0.0211081214066237 0.9999999999998812 0.0934788233721909 5 P21796,Q9UM22,P07602,P45880 4 +Phosphatidylcholine binding 0.8305025527279696 2.300634700441199 0.0214122879125013 0.999999999999923 0.0940016418017881 7 P21796,P45880 2 +Antiporter activity 0.7801595531000068 2.3003511985304645 0.0214283312494398 0.9999999999999248 0.0940016418017881 8 P12236,Q02978,P51798,Q9UBX3,O95202,P12235 6 +Sulfur compound transmembrane transporter activity 0.9210104051654556 2.2865274815904844 0.0222234182764893 0.9999999999999758 0.0965035865604491 4 Q70HW3,Q9UBX3 2 +Tap1 binding 0.8315515547054472 2.257485486051562 0.0239777553961986 0.999999999999998 0.1027074757847556 3 Q03519 1 +Peptide transmembrane transporter activity 0.8315515547054472 2.257485486051562 0.0239777553961986 0.999999999999998 0.1027074757847556 3 Q03519 1 +Sumo ligase activity 0.7505834305717658 2.257098983447382 0.0240018903984446 0.999999999999998 0.1027074757847556 2 Q96MF7 1 +Solute cation symporter activity 0.8184707491032862 2.2446909716865218 0.0247879780374686 0.9999999999999992 0.1057048445598553 7 P55011,Q96ES6,Q00325,Q9Y6M7,Q15043 5 +Peptidyl proline 4 dioxygenase activity 0.828032782038314 2.2416965928398835 0.0249809882444709 0.9999999999999996 0.1057048445598553 3 P13674 1 +Procollagen proline 4 dioxygenase activity 0.828032782038314 2.2416965928398835 0.0249809882444709 0.9999999999999996 0.1057048445598553 3 P13674 1 +Scavenger receptor activity 0.9099911958841712 2.2413185672877804 0.0250054471001808 0.9999999999999996 0.1057048445598553 4 Q8WTV0,Q14108 2 +Anion cation symporter activity 0.8266705573387843 2.23557729625118 0.0253794731637935 0.9999999999999998 0.1066396538056986 3 P55011,Q15043 2 +Wide pore channel activity 0.9049041185993814 2.2203761611980575 0.0263932438774683 1.0 0.1076586642107262 4 P21796,P45880 2 +Porin activity 0.9049041185993814 2.2203761611980575 0.0263932438774683 1.0 0.1076586642107262 4 P21796,P45880 2 +Beta n acetylhexosaminidase activity 0.9049023543249296 2.2203688902524754 0.026393737032307 1.0 0.1076586642107262 4 P17900,O60502 2 +Fad binding 0.6867869896656186 2.2168573375341576 0.0266328418865813 1.0 0.1083172432413438 13 Q15392,Q8NB78,Q14534,O15254,Q15067 5 +Potassium ion transmembrane transporter activity 0.8214181499854114 2.2119466366036824 0.0269703523308297 1.0 0.1093710508764754 3 P55011,Q9BXP2 2 +Calcium ion binding 0.3679864053644058 2.208440823985023 0.0272135586400623 1.0 0.1099711419257646 91 P80303,Q14257,P16615,O95202,P04083,P14625,P43304,Q9UM22,O43681,Q9NWM8,Q9UJS0,Q9Y680,Q96D71,Q6NUK1,O75746,P04350,O43852,Q9H223,Q9BRK5,Q9Y4G8,O95302,P41208,Q8IYU8,P27824,Q66K14,Q96AY3,O60476,Q8NF37,O75071,Q02818,Q96A33 31 +Carbohydrate derivative transmembrane transporter activity 0.7424762057866235 2.183372104040389 0.0290084185483792 1.0 0.114962340553946 9 Q6NUK1,P12236,O43808,L0R6Q1,Q8TB61,P12235 6 +Abc type transporter activity 0.7270502484548492 2.1795958529752992 0.0292874324818326 1.0 0.1154123398648489 10 P08183,Q9HD20,O14678,Q03519,Q03518,Q9NUT2 6 +Serine type exopeptidase activity 0.8028634742617996 2.171643384843334 0.0298825719260393 1.0 0.1174258812304927 7 O14773,P10619,Q9HB40,Q9H3G5,P42785 5 +Structural constituent of eye lens 0.8112051356871769 2.1658345527810843 0.0303238319408134 1.0 0.1178321603271163 3 Q99797,P08670 2 +Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water 0.8097461336445844 2.1592295623886497 0.0308323616519072 1.0 0.1191444446105558 3 O95864,O75845 2 +Phospholipid scramblase activity 0.8030030110825401 2.1286463898524235 0.0332835273727261 1.0 0.1265136803404711 3 Q4KMQ2 1 +Iron ion binding 0.5359772128009248 2.1248599145878364 0.0335983036396629 1.0 0.1268515892340999 25 Q32P28,Q9NVH6,O15460,Q16850,O75845,P22830,Q15800,P13674,O60568,Q6UW02 10 +Vitamin transmembrane transporter activity 0.8597402027296205 2.1193445046250576 0.0340613630947843 1.0 0.1277301116054413 5 P38435,P04062,Q9H2D1 3 +L serine transmembrane transporter activity 0.7222870478413062 2.116459042902354 0.0343057850615231 1.0 0.1283017966778144 2 Q9H9B4 1 +Sphingolipid binding 0.7895215439904657 2.108774063922308 0.0349640883430331 1.0 0.1300664086360831 7 P07602,P21796,Q9NZJ7,P45880,Q9UM22 5 +Amide transmembrane transporter activity 0.8768600344952076 2.1041226669224367 0.0353677480733152 1.0 0.1305190411689632 4 Q9H2D1,Q03519 2 +Oxidoreductase activity 0.3153926364861129 2.1030658700532836 0.0354600119018186 1.0 0.1305190411689632 243 Q06136,O75874,O76062,P51970,P11177,Q53GQ0,P36551,P48735,P05091,Q96CU9,Q7KZN9,O43169,O00767,O15460,Q8N0U8,O95168,Q13423,O43676,Q16134,Q15392,Q96K12,Q6DKJ4,P00403,Q9P0J0,O15254,O95831,O75306,Q32P28,Q6ZRP7,P08574,P30519,P43304,O95864,O95881,Q8NB78,Q9UHG3,P13674,P09601,Q15067,P14406,Q6IAN0,Q9Y6M9,Q3SXM5,Q9NVH6,P03886,Q9UDW1,Q709F0,P00374,Q16850,P13073,O75845,Q9BU89,Q6NUM9,Q9H7Z7,Q15800,P23378,Q14739,Q8NBX0,Q14534,O96000,P16435,P51648,Q9UBM7,P14854,Q8N4Q0,Q96LJ7,O60568,Q16836,Q9Y320,Q9NZ01,Q6UW02 71 +Tap binding 0.834213094340923 2.101070489450944 0.0356347789593824 1.0 0.1308171490745752 6 P01889,Q03518,P04439,Q03519 4 +Purine nucleotide transmembrane transporter activity 0.7380937151183531 2.089215266485224 0.0366883497889309 1.0 0.1336298902233909 8 Q6NUK1,P12236,O43808,Q8TB61,P12235 5 +Protein antigen binding 0.7129521586931178 2.0696260330217133 0.0384873782513639 1.0 0.1372900453567098 2 P30153 1 +Sterol transporter activity 0.7031054731816446 2.0520583109786883 0.0401639958269131 1.0 0.1404229929286811 10 P30536,Q9BZF1,P61916,O15118,Q14849,P22059 6 +Arylsulfatase activity 0.708284714119022 2.0461299154038666 0.0407435904213118 1.0 0.1414041382131269 2 O43681 1 +Protein lipid complex binding 0.7813561246753794 2.0298460026032688 0.0423721952293378 1.0 0.1455031447500093 3 Q9BQE5 1 +High density lipoprotein particle binding 0.7813561246753794 2.0298460026032688 0.0423721952293378 1.0 0.1455031447500093 3 Q9BQE5 1 +Procollagen proline dioxygenase activity 0.8586794682370625 2.0280439906982592 0.0425557584645188 1.0 0.1455031447500093 4 Q32P28,P13674 2 +2 acylglycerol 3 phosphate o acyltransferase activity 0.7798195995000208 2.022797495026793 0.0430940300584306 1.0 0.1469833054560163 3 Q96N66 1 +Pre mrna 3 splice site binding 0.7782316895243692 2.01550839051001 0.0438514078069218 1.0 0.1492017411967219 3 P26368,O95391 2 +Serine type carboxypeptidase activity 0.8347445255474274 2.011504991945769 0.0442721435759225 1.0 0.1502667646919999 5 Q9HB40,P10619,Q9H3G5,P42785 4 +Amino acid transmembrane transporter activity 0.7089909161294237 2.0093164167535935 0.0445035879750765 1.0 0.150685692294252 9 O75746,Q9H9B4,Q9Y619,Q9UJS0,P30825,Q96NB2 6 +Oxidoreductase activity acting on a heme group of donors 0.7666475525527183 2.0000961541559317 0.0454898819830444 1.0 0.1521783821734941 7 P13073,P00403,P14854,P16435 4 +Sodium channel regulator activity 0.70614213447445 1.9943759550979865 0.0461109842053184 1.0 0.1535198638816688 9 Q9HD47,P46934 2 +Voltage gated anion channel activity 0.8085852611248148 1.9867054979812009 0.0469550422013109 1.0 0.1555873726147952 6 P21796,Q4KMQ2,Q9Y277,P45880 4 +Intramembrane lipid transporter activity 0.8468364584607898 1.9781914403480712 0.0479071139959339 1.0 0.1575614364906935 4 P08183,Q4KMQ2 2 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen 0.8444205421729083 1.967993791620115 0.0490687520496053 1.0 0.1587019950509774 4 Q15800,Q14534 2 +Mirna binding 0.6155726916281238 1.9657667384893531 0.0493255616038601 1.0 0.1589126060909582 15 P67809,Q06787,P22626,P98175,Q9BWF3 5 +O acetyltransferase activity 0.7670721567583714 1.9641433389261416 0.0495134714929785 1.0 0.1590197938767997 3 O15228 1 +Isocitrate dehydrogenase activity 0.82174897630985 1.955006311838443 0.0505823252793806 1.0 0.1598593561994215 5 O75874 1 +Flavin adenine dinucleotide binding 0.4602509398975076 1.954471378213811 0.0506454965347733 1.0 0.1598593561994215 33 Q9Y2Z2,Q15067,P16435,Q709F0,A1L0T0,Q15392,Q8NB78,Q14534,O15254,O95831 10 +Glucosidase activity 0.8205996573107592 1.9499957216298809 0.0511766289818238 1.0 0.1600703978243144 5 P04062 1 +Amyloid beta binding 0.6545996172168695 1.9434580946258484 0.0519608338700638 1.0 0.1612832786595052 12 Q8WTV0,Q9Y287,O00264 3 +Pyruvate dehydrogenase acetyl transferring kinase activity 0.7624744674642364 1.9429114017248337 0.0520268640837113 1.0 0.1612832786595052 3 Q15118,Q15120 2 +Inorganic anion transmembrane transporter activity 0.5512912571318503 1.9385002354507317 0.0525622221189341 1.0 0.162581596132845 19 Q4KMQ2,P55011,P21796,P51798,Q9UBX3,P45880,O43681,Q9Y277,Q9C0H2,Q9Y6M7,Q15043 11 +Leukotriene c4 synthase activity 0.6846557759626635 1.9263859778204768 0.0540561969835797 1.0 0.1657597554482824 2 O14880 1 +L amino acid transmembrane transporter activity 0.7062174674525443 1.9263153505327648 0.0540650098415544 1.0 0.1657597554482824 8 O75746,Q9H9B4,Q9Y619,Q9UJS0,P30825 5 +P type calcium transporter activity 0.758097461336428 1.9226613667524608 0.0545225916697686 1.0 0.1659646195117208 3 P20020,P16615 2 +Sodium ion transmembrane transporter activity 0.8142290135433248 1.922181865526653 0.0545828778376367 1.0 0.1659646195117208 5 P55011,Q9Y6M7,Q6P4Q7 3 +Palmitoyltransferase activity 0.8133587918066548 1.9183772643074049 0.0550631917743418 1.0 0.1665508812385677 5 P23786,O15269 2 +Regulatory rna binding 0.5634461924800866 1.91542040658615 0.0554389107473667 1.0 0.1666751734753805 18 P43243,P67809,Q06787,P22626,P98175,Q9BWF3 6 +Organic cation transmembrane transporter activity 0.8295829663823481 1.9051602397848504 0.0567592448400362 1.0 0.1691862105808772 4 Q70HW3,O43772 2 +Steroid dehydrogenase activity 0.7465606665246135 1.9037599591767216 0.0569414535260435 1.0 0.1693674363940953 7 Q3SXM5 1 +Cytoskeleton nuclear membrane anchor activity 0.7530689648734634 1.8993529942733245 0.0575180794522336 1.0 0.1703560951929212 3 O94901 1 +Single stranded dna 3 5 exodeoxyribonuclease activity 0.6791131855309274 1.8981108510785416 0.0576814810412853 1.0 0.1704781060436293 2 Q07864 1 +Heparin binding 0.6433959420851993 1.8791942016113063 0.0602179810872258 1.0 0.1750085075347501 12 O14737,Q53GQ0,O94813,O14786,O43670,P05067,P30533,P10586 8 +Mrna 3 utr binding 0.3936828595339952 1.869763813583719 0.0615166235127553 1.0 0.1773051442154828 51 Q14011,P17844,P11940,Q14103,Q9BWF3,Q13151,Q01085,P07910,Q9H2U1,P31483,Q96EP5,Q06787,Q92945,P51114,P22626,Q92804,Q00839,P51116,P35637 19 +Mannose binding 0.7798132853088753 1.8568842794845095 0.0633276196197507 1.0 0.181400470984707 6 O60762,P35613,O75503,P49257 4 +Glutathione disulfide oxidoreductase activity 0.6706534422403776 1.8548220607012285 0.0636216406650422 1.0 0.1818692391961762 2 P00390 1 +Dicarboxylic acid transmembrane transporter activity 0.7356066107373764 1.8508842851207712 0.0641862020097243 1.0 0.1831078768989069 7 O75746,Q9UJS0,Q9UBX3,Q9BQT8 4 +Acetylgalactosaminyltransferase activity 0.7414648380507554 1.8453880096287296 0.064981116092508 1.0 0.1834993055648758 3 Q8N4A0,Q10472 2 +Polypeptide n acetylgalactosaminyltransferase activity 0.7414648380507554 1.8453880096287296 0.064981116092508 1.0 0.1834993055648758 3 Q8N4A0,Q10472 2 +Atpase coupled transmembrane transporter activity 0.5067260358411926 1.839318976283455 0.0658682835412962 1.0 0.1843257821984931 24 O75027,P20020,Q15388,P08183,Q9HD20,O14678,P05023,P06576,P51798,P16615,P28288,Q03519,Q03518,Q9NUT2,P23634 15 +Lipase binding 0.6659859976662822 1.8308718209554105 0.0671196772065734 1.0 0.18577767798248 2 P30533 1 +Glucosyltransferase activity 0.6839496232563288 1.81112015850138 0.0701222537244388 1.0 0.1905433056099315 8 P04062 1 +Quinone binding 0.7888160910348316 1.8105705511138093 0.0702073541817238 1.0 0.1905433056099315 5 O75306,Q8N0U8,Q16134 3 +Glycosaminoglycan binding 0.5476139663834237 1.8064126514833256 0.0708539068594114 1.0 0.1919246603279202 18 O14737,Q53GQ0,O94813,Q07021,O14786,O43670,P05067,P15586,P30533,P10586 10 +O acyltransferase activity 0.6024858764701162 1.7997868277739175 0.0718943046462439 1.0 0.1939894680493428 14 P23786,Q9NUQ2,Q96N66,O15228,Q8NCC3,P35610 6 +Snap receptor activity 0.6546305445055438 1.7892436345538905 0.0735755872094428 1.0 0.1973806618407167 10 Q86Y82,Q13190,Q9P2W9,Q13277,O95249,O15498,Q9UNK0,P51809 8 +Atp transmembrane transporter activity 0.7821897810218897 1.7813016734418172 0.0748631812694256 1.0 0.1996828639977986 5 Q6NUK1,P12236,O43808,P12235 4 +Passive transmembrane transporter activity 0.4409930378258319 1.7741693015640576 0.0760351503809473 1.0 0.2024218221019494 33 Q99797,Q4KMQ2,P21796,P24539,P45880,O75964,Q9C0H2 7 +Collagen binding 0.67638190988783 1.771725780700581 0.0764400879658222 1.0 0.2030926590933719 8 O75718,Q32P28,Q92791 3 +Exopeptidase activity 0.443300956976848 1.7627639586254067 0.0779403084706664 1.0 0.2051328989060103 32 O75844,Q96DE0,O14773,P10619,P55786,Q9UIQ6,Q9HB40,Q9H3G5,Q92820,P42785,Q6P179,Q9NZ08,O75976 13 +Serine transmembrane transporter activity 0.722497811496941 1.756672062398844 0.0789737221268351 1.0 0.206282837500317 3 Q9H9B4,Q96NB2 2 +Lipase activator activity 0.6508168028004733 1.7527184608874022 0.0796503452885508 1.0 0.206282837500317 2 P42574 1 +L ascorbic acid binding 0.6726779450401488 1.7524012116403644 0.0797048432556144 1.0 0.206282837500317 8 Q32P28,P13674,O60568 3 +Phospholipid binding 0.336377299640783 1.7516384479820302 0.0798359969907307 1.0 0.206282837500317 104 O14773,O43292,P07602,P21796,Q8WTV0,O00560,Q96L92,Q9NZJ7,P45880,Q9UM22,P50897,P04083,P22059,Q8NCC3,Q14108 15 +Acylglycerol o acyltransferase activity 0.6725024157134496 1.7514847360515078 0.0798624482803436 1.0 0.206282837500317 8 Q8NCC3,Q9NUQ2,Q96N66 3 +Galactosyltransferase activity 0.7753146569074367 1.750864338300686 0.0799692809052574 1.0 0.206282837500317 5 Q96L58,O60512 2 +Metallopeptidase activity 0.4004228282708705 1.7320181574090865 0.0832703296047476 1.0 0.2127699844933562 41 O75844,Q96DE0,Q99797,Q10713,P42892,Q9UIQ6,O95630,Q5JRX3,Q6P179,Q9NZ08,O75976,Q9BYT8 12 +2 oxoglutarate dependent dioxygenase activity 0.5365129659620005 1.7294130757193216 0.0837351914485813 1.0 0.2132347434309232 18 Q32P28,O60568,P13674,Q9NVH6 4 +Mannosidase activity 0.7164782689480547 1.7283907689606717 0.0839181893502343 1.0 0.2132347434309232 3 O60476 1 +Sulfuric ester hydrolase activity 0.715545303858844 1.7240022799375672 0.0847074315752163 1.0 0.2144589238610286 3 P15586 1 +Exogenous protein binding 0.5631208354463932 1.7204562127192704 0.0853495465213927 1.0 0.2150678575057193 16 P78310,Q8WTV0,O15118,P35613,Q14108 5 +Protein homodimerization activity 0.3037524372112188 1.7192358644701666 0.0855714328278671 1.0 0.215084952783558 186 Q99623,Q96DE0,O75874,O15217,Q9HB71,Q8NAN2,Q8TBA6,O00264,P06280,Q14849,Q8TCT9,Q8N2A8,P07602,Q16706,P16278,P28288,Q15070,P22830,Q9Y5J7,P09601,Q14108,Q15067,P42892,P23246,O95684,Q06787,Q9NZJ7,Q8IY95,P51114,O75569,P34896,Q03518,P23378,Q9BW92,P51116,Q14376,Q5HYI8,P51648,Q07820 39 +Gpi anchor binding 0.7136775814013501 1.7152127548585934 0.0863062272149446 1.0 0.2161529388955974 3 O43292 1 +Structural constituent of nuclear pore 0.5187196173698866 1.7059034153808934 0.0880260637731007 1.0 0.2187607282988738 19 Q12769,Q7Z3B4,Q99567,Q5SRE5,Q9BTX1,P35658,Q8N1F7 7 +Solute anion antiporter activity 0.7819614711033144 1.701266802751935 0.0888928987157582 1.0 0.219868073951216 4 P12235,P12236,Q02978 3 +Adp transmembrane transporter activity 0.7819614711033117 1.7012668027519235 0.0888928987157604 1.0 0.219868073951216 4 P12235,P12236,O43808 3 +Transforming growth factor beta binding 0.6388564760793433 1.6907757913495856 0.0908796324809011 1.0 0.2235927465799948 2 Q6YHK3 1 +Death receptor binding 0.6373978996499493 1.6832034970800809 0.0923357040790966 1.0 0.226376638295852 2 P42574 1 +G protein alpha subunit binding 0.7596585506628886 1.681299913443649 0.0927046747052005 1.0 0.2265828499818045 5 P80303 1 +Channel inhibitor activity 0.6993564622988224 1.6743181087674113 0.0940680974032108 1.0 0.2273340626103899 7 P46934 1 +Cytochrome b5 reductase activity acting on nad p h 0.7037181664963249 1.668253288241207 0.0952654565286086 1.0 0.2291298480300156 3 P16435 1 +Transmembrane transporter binding 0.4220068466195495 1.6629301916491182 0.0963264100159391 1.0 0.2307393274392762 35 P30536,Q9HD47,P21796,Q06787,Q96PU5 5 +Translation repressor activity 0.6419356537878943 1.6525844844091335 0.0984154579369003 1.0 0.2328259938769541 9 P34896,Q06787,P00374 3 +Single stranded rna binding 0.3733066985319838 1.6172999039155975 0.105813560033293 1.0 0.2451049758292795 44 Q00839,P31483,P31943,Q96EP5,P36776,P11940,Q06787,O14979,P07910,P26368,Q12906,P51114,Q08211,Q9Y580,Q96DH6,P23588,Q07666,P52597 18 +N6 methyladenosine containing rna binding 0.7271540685805189 1.615766617821238 0.1061447815541849 1.0 0.2451522686557748 6 Q9H6S0,P22626,Q96MU7,P07910 4 +P type transmembrane transporter activity 0.7583187390542685 1.5989159571981102 0.109839277894989 1.0 0.2495534082467584 4 P20020,P05023,P16615 3 +Oxidoreductase activity acting on the ch nh2 group of donors 0.6883571637000152 1.5955447236152962 0.1105904772027797 1.0 0.2508515702404515 3 P23378,P00367 2 +Mhc protein binding 0.6068114804901056 1.592855260745773 0.1111926648362773 1.0 0.2518080640366995 11 P51572,P06576,Q9BUN8,Q03519,Q9NUQ9,P07437,Q03518 7 +Oxidoreductase activity acting on ch or ch2 groups 0.6196032672111951 1.590525585138049 0.1117163832207346 1.0 0.2521753310565126 2 P31350 1 +Nuclear import signal receptor activity 0.5799944418252652 1.5862918837751594 0.1126731125769593 1.0 0.2535145032981585 13 P52294,O60684 2 +C4 dicarboxylate transmembrane transporter activity 0.7160706643215966 1.564519616874997 0.1176955897667282 1.0 0.263117544430426 6 O75746,Q9UJS0,Q9UBX3 3 +Peptidyl proline dioxygenase activity 0.7328847802137298 1.5615994378272668 0.1183823820053662 1.0 0.2633866393899296 5 Q32P28,P13674 2 +Pre mrna binding 0.4911387365891839 1.5413260879432584 0.123237442685899 1.0 0.2703085417402975 20 Q00839,P62995,P14866,P17844,O95391,P26368,P22626,Q01081,Q9BWF3,Q6P2Q9 10 +Lamin binding 0.620724855771591 1.53781660712453 0.1240934618587799 1.0 0.2709222548867156 9 Q9UH99,O94901,Q9ULX6,Q5SNT2,Q14739 5 +Dolichyl diphosphooligosaccharide protein glycotransferase activity 0.7425569176882478 1.5303370647019712 0.1259333183036592 1.0 0.2723674093544259 4 Q8TCJ2,P46977,P04844 3 +Oligosaccharyl transferase activity 0.7425569176882478 1.5303370647019712 0.1259333183036592 1.0 0.2723674093544259 4 Q8TCJ2,P46977,P04844 3 +Nadh dehydrogenase activity 0.4719418209369894 1.5175546486760318 0.1291267070042236 1.0 0.2773783380809593 23 O75306,P51970,Q9Y6M9,O96000,P03886,O95168,O43676,Q9P0J0,O95831 9 +Ubiquinol cytochrome c reductase activity 0.7393377995867074 1.516301136406906 0.129443224437781 1.0 0.2773783380809593 4 Q9UDW1 1 +Oxidoreductase activity acting on diphenols and related substances as donors 0.7393377995867074 1.516301136406906 0.129443224437781 1.0 0.2773783380809593 4 Q9UDW1 1 +Proteoglycan binding 0.7343500859189073 1.4945357206150125 0.1350356527599459 1.0 0.2811563217912306 4 O00560,O94813 2 +Lipid transfer activity 0.6217716929227006 1.484282493341735 0.1377339927139118 1.0 0.2850725813589125 8 P30536,Q14849,P22059,Q9BZF1 4 +Dioxygenase activity 0.4675725264772252 1.4832538617500148 0.1380069756653166 1.0 0.2852144163749877 23 Q32P28,Q9NVH6,P16435,P13674,O60568 5 +Rna strand annealing activity 0.7145799460455857 1.4793080414169866 0.1390580046486724 1.0 0.2865375428137342 5 P51114 1 +Oxidoreductase activity acting on nad p h heme protein as acceptor 0.7245638528056605 1.4517718053022783 0.1465650659849204 1.0 0.2976102868252752 4 Q7KZN9,P16435 2 +Acid phosphatase activity 0.7223883213830621 1.442255530122341 0.1492303003806301 1.0 0.3008327587152876 4 P11117,Q9NPH0 2 +Mhc class i protein binding 0.5897569688816641 1.4294034253527848 0.1528883144723571 1.0 0.3059959809023505 10 P51572,P06576,Q9BUN8,Q03519,P07437,Q03518 6 +Single stranded dna exodeoxyribonuclease activity 0.7026125648463244 1.4253490811185892 0.1540563190812689 1.0 0.3067649475389492 5 Q8IV08 1 +Oxidoreductase activity acting on nad p h 0.4098910705891602 1.4097477647141634 0.1586141754324537 1.0 0.3129657351177835 31 O75306,P51970,Q9Y6M9,P16435,P03886,Q7KZN9,Q13423,O43676,Q9P0J0,O95831 10 +Anion channel activity 0.5742213653139195 1.4059158536129357 0.1597491130733588 1.0 0.3147445899840864 11 Q9C0H2,P21796,Q4KMQ2,P45880 4 +Oxidoreductase activity acting on other nitrogenous compounds as donors 0.6817074636507594 1.404808884093807 0.1600781165772753 1.0 0.3147445899840864 6 O43169 1 +Neutral amino acid transmembrane transporter activity 0.7103168814939201 1.3893980473834306 0.1647117437322613 1.0 0.3230255575428224 4 Q9H9B4,Q96NB2 2 +Semaphorin receptor activity 0.6434199007878556 1.3812981199828789 0.1671873160341856 1.0 0.3266474872096485 3 O14786,O15031 2 +Membrane insertase activity 0.6392847336553389 1.377432645383477 0.1683785256187606 1.0 0.328509641570411 7 Q9Y5J7,Q9NPA0,Q15070 3 +Cullin family protein binding 0.6732977002843873 1.365579805767557 0.1720708885361417 1.0 0.3329249507738109 6 Q92564 1 +Gated channel activity 0.542477355446269 1.358072442854538 0.1744406983828124 1.0 0.3365764512365467 13 Q9C0H2,P21796,Q4KMQ2,P45880 4 +Ubiquitin conjugating enzyme binding 0.594960091959678 1.3416446254869372 0.1797112495314863 1.0 0.3438918972516096 8 Q92564 1 +Long chain acyl coa dehydrogenase activity 0.6977532279033665 1.3343084513606416 0.1821027889844393 1.0 0.3473641150019792 4 Q709F0,Q9NZ01 2 +Phosphatidylinositol kinase activity 0.6937471674271202 1.316731171630236 0.1879287510693235 1.0 0.3542710915428463 4 Q13315 1 +Annealing activity 0.579187453922641 1.311297003440125 0.1897574403904114 1.0 0.3569479005789834 9 P46063,P23588,Q06787,P51114 4 +Phosphatidylinositol 3 kinase regulator activity 0.5650525087514706 1.3039023995177526 0.1922668620433389 1.0 0.3605003663312606 2 O00459 1 +Pre mrna intronic binding 0.6590507564012666 1.2990473294117706 0.1939276870302573 1.0 0.3626395756128806 6 Q6P2Q9,Q9BWF3,P22626,P14866 4 +Nadp binding 0.4582630874730642 1.2963738510999303 0.1948467164228939 1.0 0.3638703740427538 20 O75874,P16435,P00374,Q13423,Q14739 5 +Poly g binding 0.6224333657376196 1.2935609361598734 0.1958171230289092 1.0 0.365193698696963 7 Q96EP5,Q06787,Q00839,O14979 4 +Nadph binding 0.6726200378889523 1.2897575021705865 0.19713486760545 1.0 0.3671426383448697 5 P00374 1 +Proline rich region binding 0.6567443310284911 1.288270840271991 0.1976516999261628 1.0 0.3671426383448697 6 P46934 1 +Phospholipase activity 0.4737922201676185 1.2874356882586064 0.1979424719135658 1.0 0.3671938142545536 18 Q8N2A8,P09601,Q8NHP8,Q8IV08,Q8NCC3 5 +Poly pyrimidine tract binding 0.4972443221842622 1.284547931894702 0.1989503036853697 1.0 0.3684430379212324 16 Q00839,P31943,Q96EP5,Q06787,P11940,P07910,P26368,Q96DH6,Q07666 9 +Phosphatidylserine binding 0.5624054919082899 1.2759190117046295 0.2019841497202965 1.0 0.3722164978333074 10 Q8WTV0,Q14108,Q9BZF1 3 +Phosphoric diester hydrolase activity 0.5403432945551476 1.2745972327599084 0.2024518374586339 1.0 0.3725861652437919 12 Q8IV08,P09601 2 +Atp dependent dna dna annealing activity 0.6208095645883341 1.272984003217123 0.2030237183979206 1.0 0.3731463599013166 3 P46063 1 +Sterol transfer activity 0.6668749991583245 1.2637553059085482 0.2063178675782446 1.0 0.3784749978501506 5 P30536,Q14849,P22059 3 +Protein arginine n methyltransferase activity 0.6486383601609464 1.2503919710822629 0.2111563960903593 1.0 0.3855538907670827 6 Q6P2P2,O14744 2 +Acidic amino acid transmembrane transporter activity 0.6765541132678927 1.241268526726227 0.2145065673304669 1.0 0.3896310695651059 4 O75746,Q9UJS0 2 +L aspartate transmembrane transporter activity 0.6765541132678927 1.241268526726227 0.2145065673304669 1.0 0.3896310695651059 4 O75746,Q9UJS0 2 +Poly purine tract binding 0.4769451853957405 1.2257245785982618 0.2203023376698403 1.0 0.3996381808185009 17 Q00839,P31483,Q96EP5,Q06787,P11940,O14979,Q86TB9,Q07666 8 +Acyltransferase activity 0.338188640086589 1.2248688230797504 0.2206246488207817 1.0 0.3997030975389486 58 P23786,O15269,Q8NCC3,O15270,Q9BWD1,Q86UY6,O15228,O14929,Q96N66,P35610,Q96G23 11 +Atpase binding 0.4094266649928694 1.1954762963373489 0.2319009919671679 1.0 0.4142149600437891 27 P55769,O76024,Q9BUN8,Q9Y487,Q8NFQ8,Q93050 6 +Calcium independent phospholipase a2 activity 0.6039773022464989 1.1923317797937456 0.233131178182715 1.0 0.415235334207209 3 Q8NCC3 1 +Phospholipase a2 activity 0.6039773022464989 1.1923317797937456 0.233131178182715 1.0 0.415235334207209 3 Q8NCC3 1 +Protein binding involved in heterotypic cell cell adhesion 0.6346814598957857 1.1851852684429454 0.2359442032111152 1.0 0.4182238417782792 6 Q99959 1 +Nucleotidase activity 0.6317023301982783 1.1712744492060705 0.2414884782849602 1.0 0.426966320922078 6 P49902,Q969T7 2 +G quadruplex rna binding 0.6599359956810006 1.1683630455551075 0.2426603545923342 1.0 0.4284951831092484 4 Q06787 1 +Lipase activity 0.4357942895940211 1.1596821586839254 0.2461782367552576 1.0 0.4341575730386655 21 Q8N2A8,P09601,Q8NHP8,Q8IV08,Q8NCC3 5 +Dynactin binding 0.6414721272568114 1.1488386276366944 0.2506225281195999 1.0 0.4395269771086985 5 Q8TD16,P42858 2 +Cyclin dependent protein serine threonine kinase regulator activity 0.641084592901622 1.1470875373141318 0.2513454440835505 1.0 0.4395269771086985 5 P42574,O95067 2 +Lysophospholipid acyltransferase activity 0.5930033878106235 1.1470144505412618 0.2513756486482148 1.0 0.4395269771086985 7 Q9NUQ2,Q96N66 2 +Atp dependent peptidase activity 0.6408029897804002 1.145815161766753 0.2518716403441221 1.0 0.4395269771086985 5 P36776,O76031 2 +Monocarboxylic acid transmembrane transporter activity 0.6534976157093875 1.1401487041122556 0.2542243539267113 1.0 0.4421323552071766 4 O14975,P53985 2 +Cyclin binding 0.5065303327015248 1.1381415195350266 0.2550613933882024 1.0 0.4421323552071766 13 Q9BWF3,Q96JB5 2 +Protein membrane adaptor activity 0.546128980136378 1.1304122063314 0.2583025730941868 1.0 0.4459555562702853 9 O94901 1 +Dynein complex binding 0.5438962146222277 1.1182126295071566 0.2634761915734827 1.0 0.4509807205460225 9 Q8TD16,Q06787 2 +Poly a binding 0.5127054554289229 1.1104145809885666 0.2668204178748532 1.0 0.4555868824178951 12 O14979,P11940,Q07666,P31483 4 +Adrenergic receptor binding 0.6321665301423329 1.1068207899074245 0.2683714178080683 1.0 0.4576749729122925 5 Q9Y4G8,P46934 2 +Calcium ion transmembrane transporter activity 0.5010827420883409 1.1048397475607332 0.2692290341238481 1.0 0.4585769262549062 13 P20020,Q93034,P16615,Q9UM00,O95202,P61619,P23634 7 +Translation repressor activity mrna regulatory element binding 0.616803059206342 1.1017848368405732 0.2705552240220426 1.0 0.4594364986028934 6 P00374 1 +C x3 c chemokine binding 0.5259626604434237 1.0979884989182014 0.2722095114014742 1.0 0.46051339567617 2 P06756 1 +Pre mirna binding 0.6290218332973965 1.0926378937494357 0.2745528181136754 1.0 0.4636818175164373 5 Q9H2U1,O75569 2 +Mitochondrial ribosome binding 0.6416810528484812 1.08844396622339 0.2763991606558837 1.0 0.4652435623476877 4 Q15070 1 +Growth factor receptor binding 0.4775111540930702 1.0828410843644285 0.2788789661260962 1.0 0.4687182623444629 15 Q9NZ08,P05067 2 +Long chain fatty acid transporter activity 0.6075246483673619 1.058611646287839 0.2897766807308668 1.0 0.4812362733566181 6 O14975,P28288,O14678 3 +Modified amino acid binding 0.4180773783105829 1.056780370377774 0.2906118350009938 1.0 0.4814768525253995 22 Q9BZF1,Q8WTV0,P00374,Q9H7Z7,Q14108 5 +Macrolide binding 0.600588422694128 1.0264076386385483 0.3046994789690131 1.0 0.5012450155209591 6 Q9Y680 1 +Fk506 binding 0.600588422694128 1.0264076386385483 0.3046994789690131 1.0 0.5012450155209591 6 Q9Y680 1 +Cysteine type endopeptidase regulator activity involved in apoptotic process 0.5997177145785395 1.0223700541478913 0.3066057882162196 1.0 0.5031942053666193 6 Q15418,Q9BXK5 2 +Acetylglucosaminyltransferase activity 0.5993528661675767 1.0206785611247338 0.3074067550663129 1.0 0.5039158910899018 6 P06865,Q8NAT1,O43505 3 +Phosphatidylinositol 3 4 bisphosphate binding 0.5090431738623267 1.009397431474185 0.3127840697945965 1.0 0.5085475260646412 2 O75146 1 +Palmitoyl protein hydrolase activity 0.6097492565491957 1.005971275498593 0.3144293878341786 1.0 0.5100599561610254 5 P50897 1 +Inositol phosphate phosphatase activity 0.622611758083124 1.0053229633396088 0.3147413612225038 1.0 0.5100599561610254 4 Q10713 1 +Aspartic type peptidase activity 0.6095392031081653 1.0050296319626817 0.3148825816382334 1.0 0.5100599561610254 5 Q8TCT9,Q92542 2 +Nuclear localization sequence binding 0.4643827512053348 0.998119723682036 0.3182213069810617 1.0 0.5132008361139667 15 P52294,O60684 2 +Molecular function inhibitor activity 0.4934479384753832 0.9964520700809224 0.3190305440833541 1.0 0.5133815982841702 12 P46934 1 +Threonine type endopeptidase activity 0.5296021156317099 0.9936732959997192 0.3203819475063452 1.0 0.5140874582472106 8 P49721,P28072 2 +Carboxypeptidase activity 0.4807317904055718 0.9808347412433828 0.3266742430707996 1.0 0.521339933342427 13 P10619,Q9HB40,Q9H3G5,P42785,O75976 5 +Racemase and epimerase activity acting on carbohydrates and derivatives 0.6164663853771111 0.9786503435101452 0.327752775298429 1.0 0.521339933342427 4 Q9UL01 1 +3 5 dna helicase activity 0.5132122462107676 0.951329635863736 0.3414370672713303 1.0 0.5368142264886873 9 Q14566,P46063,Q08211 3 +Hormone binding 0.5201102475790207 0.9436030584488266 0.3453725287540268 1.0 0.541599821971337 8 P30536 1 +Acyl coa oxidase activity 0.5503641702072756 0.9371980757494736 0.3486566794241676 1.0 0.5440448185645569 3 O15254 1 +Voltage gated channel activity 0.4865486116417247 0.9013915044396914 0.3673801968207153 1.0 0.5613311879133602 11 P21796,Q4KMQ2,P45880 3 +Phospholipid transporter activity 0.5109127364741256 0.8953314692672593 0.3706099227295207 1.0 0.5644113997900453 8 P08183,Q4KMQ2,Q96GC9 3 +Signaling receptor inhibitor activity 0.4822053675612772 0.870438671687976 0.3840607207634663 1.0 0.5829866218335533 2 P30533 1 +Nucleocytoplasmic carrier activity 0.3959933426120627 0.8577267077186141 0.3910433888351741 1.0 0.5907609519595312 21 Q8TEX9,Q9HAV4,O60684,Q92973,Q9C0E2,Q96QU8,P52294,P35658 8 +C acyltransferase activity 0.4787592963419914 0.857262682590399 0.3912997273194314 1.0 0.5907609519595312 11 O15269,O15270,P35610 3 +Carbohydrate binding 0.3083153603378049 0.8489214233669752 0.395925017097446 1.0 0.593887525646169 47 P52789,O15460,P35613,P08236,Q32P28,Q16706,Q8N4A0,P49257,P10253,P13674,Q9NPA0,Q10472,Q13438,P27824,O60762,Q04446,O75503,Q12907,O60568 19 +Protein dimerization activity 0.2622967654990117 0.8434084379504927 0.3990000544152854 1.0 0.5972157466838232 242 Q99623,Q96DE0,O75874,O15217,Q9HB71,Q8NAN2,O14965,O00560,Q8TBA6,O00264,P06865,P06280,Q14849,O95831,Q8TCT9,Q4KMQ2,Q8N2A8,P07602,Q16706,P16278,P28288,Q15070,P22830,Q9Y5J7,Q9Y6J9,P09601,Q14108,Q15067,P42892,P23246,O95684,Q06787,O14744,Q9NZJ7,Q8IY95,P51114,O75569,P34896,Q03518,Q8IYU8,P23378,Q9BW92,P51116,P05023,Q14376,Q5HYI8,P51648,Q07820,O76031 49 +Sirna binding 0.5837880131967732 0.8382077444604901 0.4019140382903394 1.0 0.6009325652894143 4 Q06787 1 +Guanylate kinase activity 0.5831434588722835 0.8354670792059142 0.4034547751945543 1.0 0.6025903762274125 4 Q14168 1 +Mrna 3 utr au rich region binding 0.4557242741850018 0.830111817479802 0.4064755662207973 1.0 0.6058049304252267 13 P31483,Q13151,Q01085,Q92945,Q14103 5 +Chemokine binding 0.5261161365626056 0.8239458305315761 0.4099703378156958 1.0 0.6090613644865769 3 P09429,P06756 2 +Cell cell adhesion mediator activity 0.397472308997406 0.8198620836654413 0.412294733956857 1.0 0.6118629296487399 19 P35613,Q9UQB8,Q99959,P04083 4 +Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor 0.5792680711487088 0.8190177756005413 0.4127762719684604 1.0 0.61188459211957 4 P21953,P11177 2 +Protein phosphatase 2a binding 0.4718420668099328 0.8182988111604176 0.4131865847861182 1.0 0.61188459211957 11 P78318,Q9Y570,Q86XL3 3 +Channel regulator activity 0.3865673270495891 0.7872417519372737 0.4311403602957919 1.0 0.6304410928853562 21 Q9HD47,P46934 2 +Cobalamin binding 0.5695102976272328 0.7778361112147374 0.4366656363734165 1.0 0.6351914105744693 4 Q99707 1 +Nedd8 specific protease activity 0.5141523198132626 0.768908981943707 0.4419473449421121 1.0 0.6408695906385097 3 Q96FW1,Q9BT78 2 +Lysophospholipase activity 0.5108334979512291 0.7448526306979689 0.4563608139501056 1.0 0.6559295838749731 7 Q8NCC3 1 +Mdm2 mdm4 family protein binding 0.5335038271111274 0.7210799951063298 0.4708602984447332 1.0 0.6682096809058015 6 Q96JB5 1 +Histone serine kinase activity 0.5516495402286754 0.7034677639610726 0.4817642892615505 1.0 0.678849680323094 4 O14965,P54646 2 +Cytoskeletal anchor activity 0.4991716688054848 0.6898194716968065 0.4903077220460805 1.0 0.6857721317850373 7 O00560,Q9UQB8 2 +O methyltransferase activity 0.470697057237195 0.6885818205125667 0.4910864645969937 1.0 0.6857721317850373 8 O60725 1 +G protein activity 0.4233184913822142 0.6859006613835639 0.4927757531056678 1.0 0.6867354401422643 14 Q15907 1 +Signaling receptor regulator activity 0.4057619175419149 0.6815552241442572 0.4955202359625281 1.0 0.6887347550254893 16 P43490 1 +Translation initiation factor binding 0.3955394740497889 0.6729101470632443 0.5010044563138907 1.0 0.6947328196400373 17 Q06787,P55010 2 +Protein methyltransferase activity 0.346855931232972 0.6629045307352848 0.5073916998147481 1.0 0.7001102089431984 27 O60725,O14744,Q9H7B4,Q6P2P2,O96028,Q7L592 6 +Cysteine type endopeptidase inhibitor activity involved in apoptotic process 0.5408368683358042 0.6591947242807403 0.5097707342982116 1.0 0.7014662073504404 4 Q15418 1 +Sh2 domain binding 0.4568523784642638 0.6535964965801758 0.5133718019486322 1.0 0.7041825601950265 9 P46108,Q8NEM2 2 +Acetyl coa hydrolase activity 0.4858443872628805 0.641743378409319 0.521039818968223 1.0 0.7125985759418344 3 O14734 1 +Cation channel activity 0.371620621298847 0.6364286634420092 0.5244970633919233 1.0 0.716624293273 19 P24539,O75964 2 +Bh domain binding 0.4823891818821483 0.6265789387068884 0.5309352775743839 1.0 0.72258996313782 3 Q07820 1 +Bh3 domain binding 0.4823891818821483 0.6265789387068884 0.5309352775743839 1.0 0.72258996313782 3 Q07820 1 +Molecular carrier activity 0.318557432129946 0.620831563049605 0.5347104536706364 1.0 0.7256041662164765 34 Q9HAV4,Q9NPA0,O60684,P40855,Q92973,Q5J8M3,Q9C0E2,Q15070,P52294,Q9Y5J7,P35658 11 +Coa hydrolase activity 0.4557776400758697 0.6144578669601591 0.5389128068053413 1.0 0.7298867626150011 8 P28288,O14734,P50897 3 +Threonine type peptidase activity 0.4467741115215878 0.6025170359251559 0.5468300267193977 1.0 0.7356722997096914 9 P49721,P28072 2 +Rna directed dna polymerase activity 0.4765100671141105 0.600984204061481 0.5478505072211084 1.0 0.7356722997096914 3 Q15185,Q15554 2 +Telomerase activity 0.4765100671141105 0.600984204061481 0.5478505072211084 1.0 0.7356722997096914 3 Q15185,Q15554 2 +Atpase activator activity 0.4243904380588714 0.6001953938087267 0.5483760230852939 1.0 0.7356722997096914 12 Q8NFQ8 1 +Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor 0.5149775016615449 0.595202837055777 0.5517078941163851 1.0 0.7393203768418417 5 Q9UHG3 1 +Cadherin binding involved in cell cell adhesion 0.4306666555530917 0.5927103440112304 0.5533750176333743 1.0 0.7394684498461115 11 Q9UQB8 1 +Palmitoyl coa hydrolase activity 0.5035322793321201 0.5910770203209392 0.5544688161570126 1.0 0.7394684498461115 6 P50897 1 +Virion binding 0.4244457409568508 0.5844324700139131 0.5589293865070091 1.0 0.7432855044587967 2 Q99816 1 +Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor 0.3402510569651106 0.5448506509516021 0.5858562392730791 1.0 0.7702822373100332 25 O75306,P51970,Q9Y6M9,O96000,P03886,O95168,O43676,Q9P0J0 8 +Sequence specific mrna binding 0.461127857620013 0.5169800441221438 0.6051700894958707 1.0 0.7884065191153166 7 P00374 1 +Ccr5 chemokine receptor binding 0.40985997666279 0.516804344554327 0.6052927469336946 1.0 0.7884065191153166 2 P48681 1 +Cyclin dependent protein kinase activity 0.4351770258081349 0.5153878187452668 0.6062820428977052 1.0 0.7889475809949824 8 P21127,Q9NYV4 2 +Metalloexopeptidase activity 0.3471172794191995 0.5023323904768385 0.6154337285624871 1.0 0.7934415384894549 21 O75844,Q96DE0,P55786,Q9UIQ6,Q6P179,Q9NZ08,O75976 7 +S methyltransferase activity 0.5007651700193106 0.5015506426734866 0.6159836460100929 1.0 0.7934415384894549 4 Q99707,Q6UX53 2 +Protein carrier chaperone 0.4189811744617974 0.4970313399965572 0.619166951020123 1.0 0.796806177742686 10 Q9Y5J7,Q9NPA0,P40855,Q15070 4 +Oxidoreductase activity acting on the ch ch group of donors 0.3086232470822551 0.4761837883397667 0.633943448055029 1.0 0.8101036797686985 31 O76062,Q9H7Z7,P36551,Q709F0,Q8N4Q0,Q7KZN9,Q9UBM7,Q14739,Q6NUM9,Q15392,P49327,P21912,O15254,Q9NZ01,Q15067 15 +Rna stem loop binding 0.4254646252905973 0.470275080179388 0.638158499058485 1.0 0.8107751422464359 8 Q06787,Q08211 2 +Pentosyltransferase activity 0.3709496510715847 0.4675632579111398 0.6400969451093497 1.0 0.8124979421542701 16 P43490 1 +Prenyltransferase activity 0.4214529067073404 0.451981387765139 0.6512823908222733 1.0 0.8236980373500192 8 Q5T2R2,P49354,P37268 3 +N methyltransferase activity 0.3156281138660609 0.4441110943017571 0.6569622657806033 1.0 0.8278792780162074 28 O75648,O14744,Q9H7B4,Q6P2P2,O96028,Q7Z2T5 6 +Plus end directed microtubule motor activity 0.4751592802295561 0.4382841423388201 0.6611803197755863 1.0 0.8311390435776621 5 P33176,Q9Y496 2 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.4751019633382168 0.4380687549913956 0.6613364432768494 1.0 0.8311390435776621 5 O15254,Q15067 2 +Peptide lysine n acetyltransferase activity 0.4001391257220243 0.4362284876085753 0.6626709609759225 1.0 0.8320665981650872 11 Q86UY6 1 +Ephrin receptor binding 0.4402275592648002 0.4278268431405734 0.6687771921883723 1.0 0.8366325969118614 7 O00560 1 +Calmodulin dependent protein kinase activity 0.4781085814360828 0.4181695490259038 0.6758231579199729 1.0 0.8402614129218915 4 Q14012,Q13557,Q13555 3 +N acyltransferase activity 0.3340402900356594 0.4134644965936692 0.6792663291059666 1.0 0.8437903197709915 21 Q86UY6,O14929 2 +Protein self association 0.3951229105562892 0.4117423466354836 0.6805282830121073 1.0 0.844605831674279 11 P28288,P46108,Q9Y282 3 +Cell adhesion mediator activity 0.3321488786684486 0.4009252374672866 0.6884751683023955 1.0 0.849931734320214 21 P35613,Q9UQB8,Q99959,P04083 4 +Ubiquitin like protein binding 0.2695205368577518 0.3894285285423259 0.6969591716364487 1.0 0.8566150171214502 43 Q92564,Q8TAF3,P46934 3 +Atpase coupled cation transmembrane transporter activity 0.3770258688485576 0.387857066364973 0.6981218118407966 1.0 0.8567191720590378 13 P20020,Q9HD20,P05023,P16615 4 +Molecular function activator activity 0.3765819655998643 0.3855979999336417 0.699794414711923 1.0 0.8570791997569207 13 Q8NFQ8 1 +Peptide n acetyltransferase activity 0.3737796023668813 0.3714215091116319 0.7103236075831636 1.0 0.8639070903038476 13 Q86UY6 1 +3 hydroxyacyl coa dehydrogenase activity 0.4244380307543064 0.3640012257189804 0.7158570940886895 1.0 0.8683657793510624 7 Q16836,Q53GQ0 2 +Misfolded protein binding 0.3580857411204517 0.3555672043024753 0.7221647077480844 1.0 0.873301621634816 15 P46379,Q9UBS4,Q9BUN8,Q9UBN7,Q6NTF9 5 +Demethylase activity 0.3764936581812772 0.3524995992642724 0.7244636189466429 1.0 0.8735480289672127 12 Q8NB78 1 +Proton transporting atp synthase activity rotational mechanism 0.3881549009328967 0.3515992950760426 0.7251387939383744 1.0 0.8735480289672127 10 O75964 1 +Proton channel activity 0.3881549009328967 0.3515992950760426 0.7251387939383744 1.0 0.8735480289672127 10 O75964 1 +Dna polymerase activity 0.3877005903319451 0.349569717004268 0.726661641036852 1.0 0.8744716219904909 10 Q15185,P28340,Q07864,Q9Y2S7 4 +Arachidonate coa ligase activity 0.4499989963510414 0.3472374727689566 0.7284129209698569 1.0 0.8744716219904909 5 O14975,O60488,O95573 3 +Long chain fatty acid coa ligase activity 0.4499989963510414 0.3472374727689566 0.7284129209698569 1.0 0.8744716219904909 5 O14975,O60488,O95573 3 +Telomerase rna binding 0.3662568495871753 0.3341213314670314 0.7382880039709194 1.0 0.8810194743707721 13 Q9H2U1,Q00839,Q9NY12 3 +Ubiquitin like protein conjugating enzyme binding 0.3718026052502117 0.3302563081265441 0.7412063035436953 1.0 0.8837459773020983 12 Q92564,Q9BTE7 2 +Fatty acid ligase activity 0.4361999998861626 0.327056215707137 0.7436253670585913 1.0 0.8851172244426065 6 O14975,O60488,O95573,P33121 4 +Oxidoreductase activity acting on the ch nh group of donors 0.3808289202879572 0.3193281960737074 0.7494776536508385 1.0 0.889048747315408 10 P00374 1 +Dna directed dna polymerase activity 0.4113483142049349 0.3137617780200209 0.7537019761385304 1.0 0.8921012148984285 7 P28340,Q07864,Q9Y2S7 3 +Phosphatidylinositol monophosphate phosphatase activity 0.4034484752475447 0.3125679737915 0.7546089129606779 1.0 0.8921012148984285 3 Q9NTJ5 1 +Phospholipase binding 0.445709281961477 0.308410124610546 0.7577702788839373 1.0 0.89273630205842 4 P07196,P20700,P84103 3 +Phosphatase activator activity 0.4303729978572981 0.3067137520714545 0.7590612613583483 1.0 0.89273630205842 6 Q14738 1 +Protein adp ribosylase activity 0.3994747592646795 0.2989004008168205 0.7650160412718556 1.0 0.8968045189699485 3 Q7Z2W4,Q9UGN5 2 +Dna replication origin binding 0.3631580267367308 0.2904371298718499 0.7714818417181262 1.0 0.9026296046276098 12 Q9UBD5,Q9Y619 2 +Protein phosphatase activator activity 0.4328928500907845 0.2898047408589203 0.7719656207637144 1.0 0.9026296046276098 5 Q14738 1 +Death domain binding 0.4390069631355879 0.2873198975509051 0.7738673886269687 1.0 0.9026296046276098 4 Q07812,Q07820 2 +Monosaccharide binding 0.2947871006837647 0.2852110236696952 0.7754824752950704 1.0 0.9035662601574368 28 Q32P28,P52789,O60762,O75503,O15460,Q12907,P49257,P35613,P13674,O60568 10 +Acetylcholine receptor binding 0.3526837806301077 0.281096744228994 0.7786361982671859 1.0 0.9044109047316606 2 O15258 1 +Dna dna annealing activity 0.4357569951323585 0.2773110305984625 0.7815412903918537 1.0 0.9059311366796604 4 P46063 1 +Carboxylic ester hydrolase activity 0.2765990325234205 0.2768526477474013 0.7818932534496854 1.0 0.9059311366796604 36 Q14197,Q9NP80,P05091,Q15165,O14734,Q9Y570,Q8NCC3,Q9NUJ1,Q9BW92 9 +Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity 0.3491831971995313 0.2685685649863399 0.7882617052663854 1.0 0.9087810568980228 2 Q9Y217 1 +Peroxisome targeting sequence binding 0.3878027429238603 0.2602459683191051 0.7946740478850498 1.0 0.9131551044478128 3 P40855,Q9NXR7 2 +G quadruplex dna binding 0.4203186887276563 0.250197995547304 0.8024342352938314 1.0 0.9195972966876668 5 Q9H2U1,P36776 2 +Peptidase activator activity 0.3591945113141793 0.2495734799995776 0.8029172095810595 1.0 0.9195972966876668 11 P05067,Q9BXK5 2 +Intermediate filament binding 0.4183057961461276 0.2440761945306151 0.8071718090853897 1.0 0.9204207878402983 5 P08670 1 +Growth factor binding 0.3352962586943794 0.2404755180604714 0.8099616402506871 1.0 0.9216121436783918 15 O14786,P27695,O00560,Q92896,O43847,Q99523,Q6YHK3 7 +Exodeoxyribonuclease activity 0.3612378657353378 0.2382061926466068 0.8117211743106956 1.0 0.9217123049406328 10 P27695,Q9UQ84,Q8IV08,Q07864 4 +Atp dependent chromatin remodeler activity 0.4160583941605886 0.2373145995441985 0.8124127367748524 1.0 0.9217123049406328 5 Q9H4L7,Q9BXF3,O60264,P28370 4 +Histone kinase activity 0.3509070093766385 0.2368200219972265 0.812796418028989 1.0 0.9217123049406328 12 O14965,Q9UIG0,P54646,Q96GD4 4 +5 3 exonuclease activity 0.3598590539568984 0.2328032339199199 0.815914201612151 1.0 0.9223665407203814 10 Q8IV08 1 +Scaffold protein binding 0.298664617126888 0.2309677804478532 0.8173398327865089 1.0 0.9232300135523724 24 Q16543,P07602,Q9NZJ7,P08670,Q9UQB8 5 +Protease binding 0.2864925604370154 0.2048683828296689 0.8376749581079972 1.0 0.9348868858867404 27 P46379,Q2T9J0,P07602,Q9BUN8,O75955,Q9NZJ7,P54725,Q6NTF9,Q13438 9 +Sumo transferase activity 0.4105477738816664 0.2048206363396163 0.8377122633393732 1.0 0.9348868858867404 4 P49792,Q96MF7 2 +Acetyl coa c acetyltransferase activity 0.3979359113424842 0.2028878443264218 0.8392226955151838 1.0 0.9358238690996654 6 P35610 1 +Minus end directed microtubule motor activity 0.3287631271878645 0.20075330033264 0.8408914803727083 1.0 0.9369357948242236 2 Q8NCM8 1 +Rrna adenine methyltransferase activity 0.3656259118762855 0.1933833075025543 0.8466587873730675 1.0 0.9418572634652546 3 Q9UNQ2,Q9H5Q4 2 +Phosphatidylinositol phosphate 4 phosphatase activity 0.3641669098336884 0.1893041689883891 0.8498544280224942 1.0 0.9423422347896736 3 Q9NTJ5,Q01968 2 +Myosin binding 0.3388683559289704 0.1876540858000985 0.851147824971318 1.0 0.9423422347896736 12 Q15907 1 +U3 snorna binding 0.3469025126648402 0.1841647218843223 0.853884233938407 1.0 0.9438736183392058 10 P78527,P55769 2 +Beta tubulin binding 0.2960612864190256 0.1813955642448566 0.8560571003455424 1.0 0.9453733163741112 21 Q9H6U6,P42858,Q7L7X3,O14737,P50402,Q9UBN7,Q9UBK9 7 +Nuclear export signal receptor activity 0.3511600331636993 0.1741575274183965 0.861741663579217 1.0 0.948800016332287 8 Q9HAV4,Q9C0E2,P35658 3 +Vitamin d receptor binding 0.3503798947983679 0.1716244254021394 0.8637328036771323 1.0 0.949493507588337 8 Q15648,O60244,Q13573,O75448,Q9Y2W1,Q9NVC6,Q9NPJ6 7 +Racemase and epimerase activity 0.3919104399067652 0.1697704816642948 0.8651906421174185 1.0 0.950347201380944 5 Q9UL01 1 +C acetyltransferase activity 0.3667629100736986 0.1644717538238471 0.8693597811096916 1.0 0.9526762723079496 7 P35610 1 +Transferase activity transferring sulphur containing groups 0.3399412533949584 0.1596944389397133 0.8731217817657575 1.0 0.954915797354823 10 Q7LGA3,Q06520 2 +Mismatch repair complex binding 0.3912984365087442 0.1560548814852053 0.8759897619138144 1.0 0.9554284440303548 4 Q13535 1 +Mutlalpha complex binding 0.3912984365087442 0.1560548814852053 0.8759897619138144 1.0 0.9554284440303548 4 Q13535 1 +Ubiquitin specific protease binding 0.3421279647030116 0.1551976184976972 0.8766655257052718 1.0 0.9554284440303548 9 P46379,Q9BUN8,Q6NTF9 3 +14 3 3 protein binding 0.3890834792761307 0.1508298810746805 0.8801099142226656 1.0 0.956853410030513 4 O14974,P78362,Q9Y580 3 +Phosphatidylinositol 3 5 bisphosphate phosphatase activity 0.3492850889991318 0.150060748931959 0.8807166870818486 1.0 0.956853410030513 3 Q01968,Q9Y217 2 +Ribosomal large subunit binding 0.3388802647830694 0.1447588389029172 0.884901281626916 1.0 0.9587325916263107 9 P98179,Q9NTK5 2 +Microfilament motor activity 0.335087719298247 0.1433515124377876 0.8860125748468572 1.0 0.9587325916263107 10 O94832,P35580,P60660,P35579,O43795,Q12965,Q9UM54,Q9Y4I1,O00159 9 +N acetyltransferase activity 0.3020354656536997 0.1392189190545066 0.8892771588434156 1.0 0.9609152878284778 17 Q86UY6 1 +Dna secondary structure binding 0.3315265657736953 0.1317444569259366 0.8951864204208924 1.0 0.9644513185533647 10 Q03164,Q14103 2 +Isopeptidase activity 0.3345672970537072 0.1312977340459696 0.8955397842441437 1.0 0.9644513185533647 9 O95630,Q9H4L4 2 +Acetyl coa c acyltransferase activity 0.3344677389223116 0.1230553112982937 0.902063298662464 1.0 0.9702222834496046 8 P35610 1 +Acetyltransferase activity 0.2609327729189657 0.1169036092276641 0.9069364380172492 1.0 0.9739617636905792 32 Q9BWD1,Q86UY6,P35610,O14929 4 +Microtubule minus end binding 0.3648629242509102 0.1155806287052957 0.9079849160531284 1.0 0.9739804453684618 6 Q9H6D7 1 +Protein phosphatase regulator activity 0.282004814048067 0.1084508234508228 0.9136380875520502 1.0 0.9788979509486252 21 P30154,Q9Y570,Q16537,Q14738,Q86XL3 5 +Transferase activity transferring one carbon groups 0.2398281832851128 0.0984250138848591 0.9215948129026994 1.0 0.9843214229205698 70 O60725,Q6UX53,Q15022,Q8N6Q8,O75648,Q7L592,O14744,Q9H7B4,Q8IYR2,Q6P2P2,O96028,Q7Z2T5,Q99707,P21964 14 +Phosphatidic acid binding 0.3636360950488833 0.0967122079774824 0.9229549447160164 1.0 0.9843214229205698 4 O60313 1 +Nadplus binding 0.3405384379998792 0.0949622030936759 0.9243448487641192 1.0 0.9843214229205698 7 Q7Z2W4,Q16836,P00367 3 +Methylated histone binding 0.2685196951524232 0.0936101879302341 0.925418816357271 1.0 0.9847133858263868 27 Q06787,Q7Z4V5,Q9H2V7,P42695 4 +Fatty acid binding 0.3181552340042622 0.0911430739231953 0.9273789070113276 1.0 0.98604693237866 10 O15254,Q15067 2 +Phosphatidylinositol 4 phosphate binding 0.3196319958255726 0.0832707350582467 0.9336362694982084 1.0 0.9897323969671462 8 Q9H4A6,P22059,Q9BZF1 3 +Ribosome binding 0.246012258299008 0.0804498626179909 0.935879470752116 1.0 0.9903516804894116 39 P46379,P42345,Q06787,P04844,Q15070,Q9NTK5,Q96A33 7 +Lys48 specific deubiquitinase activity 0.3484228971962689 0.079799103991342 0.9363970369645404 1.0 0.9903516804894116 6 Q93009,Q93008,Q9Y4E8,Q6GQQ9,Q9H8M7 5 +Chloride channel inhibitor activity 0.3116428362999829 0.0706712178879952 0.9436594283421356 1.0 0.9920157517236466 3 Q9UNK0,O15400 2 +Pdz domain binding 0.296406394342915 0.0651773569744818 0.9480327893044274 1.0 0.9951134244391844 14 P20020,P78310,Q15067,Q9Y4G8,Q9UQB8,P23634 6 +Mhc protein complex binding 0.3184394610410973 0.0478724730697923 0.9618178775374232 1.0 1.0 7 P07900,Q9NUQ9 2 +Histone deacetylase activity h3 k14 specific 0.2935665431597365 0.0426507271847397 0.9659799578069131 1.0 1.0 3 Q9UBN7 1 +Notch binding 0.285380799533131 0.0320097926338448 0.9744642415079257 1.0 1.0 3 Q13573,Q9H3F6 2 +Dna polymerase binding 0.2944302616680156 0.0310335573213729 0.9752427776814664 1.0 1.0 10 P51532,Q9BXW9,P36776,Q9H0A0,P08238,Q15185,P07900 7 +Thiolester hydrolase activity 0.2804194592244794 0.0260337019631835 0.9792304572750524 1.0 1.0 15 Q9Y305,O14734,P28288,P50897,Q9NUJ1 5 +Chloride channel regulator activity 0.3117338003502695 0.0199681782642751 0.984068757568396 1.0 1.0 4 Q9UNK0,Q96BR1,O15400 3 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4908815c8cc40c58c7fd5695b43bbcee908efb63 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 3 kinase regulator activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "3 phosphoadenosine 5 phosphosulfate binding", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5alpha androstane 3beta 17beta diol dehydrogenase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenosine receptor binding", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid proton symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminoacyltransferase activity", "Aminopeptidase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Angiotensin receptor binding", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide binding", "Cgmp binding", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase activator activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase activity involved in apoptotic process", "Cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Delta catenin binding", "Demethylase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix protein binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Fatz binding", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H3 histone acetyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di monomethyl lysine 4 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Icosanoid binding", "Identical protein binding", "Ige binding", "Igg binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Mutsalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin light chain binding", "Myosin v binding", "Myristoyltransferase activity", "N acetyllactosamine synthase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neuregulin binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nf kappab inducing kinase activity", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opsonin binding", "Organic acid binding", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on metal ions", "Oxidoreductase activity acting on metal ions nad or nadp as acceptor", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreductase activity acting on the ch nh2 group of donors oxygen as acceptor", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Patched binding", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphorylation dependent protein binding", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retinol binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel inhibitor activity", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Titin binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor binding", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor activated receptor activity", "Vascular endothelial growth factor binding", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Wnt protein binding", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT4", "AGPAT5", "AGPS", "AGTPBP1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "APBB1", "APEH", "APEX1", "API5", "APIP", "APMAP", "APOL2", "APP", "APRT", "AQR", "ARAP1", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL6IP1", "ARL8A", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATM", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPIF1", "ATR", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC115", "CCDC124", "CCDC22", "CCDC47", "CCDC6", "CCDC86", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPV", "CEP250", "CEP290", "CEP44", "CEP55", "CEP97", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHM", "CHMP5", "CHORDC1", "CHRAC1", "CHTF18", "CHTF8", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT4", "CNOT7", "CNP", "COASY", "COIL", "COLGALT1", "COMMD7", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC22", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND5B", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2A", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DR1", "DRG1", "DRG2", "DSC2", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFCAB14", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETHE1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC8", "EXOG", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EYA4", "EZR", "FABP5", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM105A", "FAM120A", "FAM129B", "FAM208A", "FAM20B", "FAM213A", "FAM49B", "FAM50A", "FAM83D", "FAM98A", "FAM98B", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAU", "FBL", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FSD1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALE", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GID8", "GIGYF2", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP6", "GTPBP8", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS4", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90AB4P", "HSP90B1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS11", "INTS6", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "JUP", "KARS", "KAT7", "KATNB1", "KCTD10", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KMT2A", "KNSTRN", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC14", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRFIP1", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LZTFL1", "M6PR", "MACF1", "MAGED1", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP2", "METTL13", "METTL25", "METTL7B", "MFAP1", "MFGE8", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA3", "MICAL3", "MICALL1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMACHC", "MMS19", "MOCS1", "MOCS2", "MOCS3", "MOGS", "MORC2", "MORC3", "MORF4L1", "MOV10", "MPC2", "MPDZ", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFR", "MTIF2", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NET1", "NEU1", "NF1", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NMD3", "NME1", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTPCR", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PARS2", "PATL1", "PAWR", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDSS1", "PDSS2", "PDXDC1", "PDXP", "PEBP1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF6", "PHGDH", "PHIP", "PHLDB2", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POR", "POU2F1", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRUNE1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB36", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RABEP1", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAF1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RASAL2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REL", "RELA", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RGS10", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RTCB", "RTF1", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL1", "SCYL2", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFMBT1", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGK3", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIN3A", "SIPA1", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SMYD4", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX14", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRA1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAB1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TAPBP", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2", "TERF2IP", "TES", "TEX264", "TFAM", "TFB1M", "TFB2M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM7SF2", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM192", "TMEM201", "TMEM43", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TNRC6A", "TOE1", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TONSL", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC26", "TTC28", "TTC4", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR2", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "URB1", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP32", "USP34", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMP1", "VPS16", "VPS18", "VPS25", "VPS28", "VPS33B", "VPS35", "VPS37B", "VPS4A", "VPS4B", "VPS72", "VRK1", "VRK2", "VRK3", "WARS", "WASF2", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR48", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WLS", "WNK1", "WRAP53", "WTAP", "WWP2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO6", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YKT6", "YLPM1", "YME1L1", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABHD10", "ACAD11", "ACAT2", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "AGPAT5", "AIFM1", "AKAP8L", "ALDH2", "ALDH3A2", "ALG1", "ALG11", "ANKLE2", "ANO6", "ANXA1", "APEX1", "APOL2", "APP", "ASNA1", "ATM", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP5F1", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATR", "AURKA", "AURKB", "B3GALT6", "B4GALT3", "B4GAT1", "BABAM2", "BAG6", "BAIAP2", "BAX", "BAZ1B", "BCAP31", "BCAS3", "BCKDHB", "BCL2L13", "BICD2", "BSG", "C1QBP", "CACYBP", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CANX", "CASP3", "CCDC47", "CCNB2", "CD109", "CDC37", "CDK11B", "CDK12", "CDK5RAP3", "CECR2", "CERS2", "CETN2", "CIRBP", "CLCN7", "CLN5", "CLPX", "CNNM3", "CNNM4", "COMT", "COPS4", "COX15", "COX2", "COX4I1", "COX6B1", "COX7A2", "CPD", "CPOX", "CPT2", "CPVL", "CRK", "CRTAP", "CTSA", "CUL5", "CXADR", "CYB5B", "CYB5D2", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAZAP1", "DCUN1D4", "DCUN1D5", "DDX5", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7B", "DHX36", "DHX9", "DIMT1", "DNAJB11", "DOHH", "DPM1", "DSE", "DYNC2H1", "ECE1", "EFCAB14", "EHD4", "EIF4B", "EIF5", "EMC4", "EMC7", "EMD", "EPDR1", "ERAP1", "ERAP2", "ERGIC3", "ERLIN1", "ESPL1", "ETFDH", "EXO1", "EXTL3", "FADS2", "FAM49B", "FANCD2", "FAR2", "FASN", "FCGRT", "FDFT1", "FECH", "FGFR1OP", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "FLOT1", "FMR1", "FNTA", "FOXRED1", "FUCA2", "FUS", "FXR1", "FXR2", "GAA", "GALE", "GALNT1", "GALNT4", "GAR1", "GBA", "GBE1", "GGCX", "GGH", "GLA", "GLB1", "GLDC", "GLG1", "GLUD1", "GM2A", "GNPAT", "GNS", "GOLGA5", "GOLPH3", "GOSR1", "GPAA1", "GPD2", "GSR", "GSTA4", "GUSB", "GYG1", "HADH", "HAT1", "HAUS4", "HCCS", "HDAC6", "HDGFL2", "HEBP2", "HEXA", "HIP1R", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMCES", "HMGB1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPL", "HNRNPU", "HS2ST1", "HSD17B12", "HSDL1", "HSP90AA1", "HSP90AB1", "HSP90B1", "HTT", "ICMT", "IDH1", "IDH2", "IGBP1", "ILF3", "ILVBL", "IPO4", "ITGAV", "ITM2B", "ITM2C", "KCTD10", "KDELR1", "KDELR3", "KDM1B", "KDSR", "KHDRBS1", "KHSRP", "KIF3A", "KIF5B", "KMT2A", "KPNA1", "KPNA6", "LBR", "LETM1", "LMAN1", "LMAN2", "LMNB1", "LNPEP", "LONP1", "LPCAT1", "LRPAP1", "MAGT1", "MAN1A2", "MAN2A1", "MATR3", "MBOAT7", "MCL1", "MCM6", "MED1", "MED14", "MED17", "MED24", "MED4", "METTL25", "METTL7B", "MFSD10", "MFSD3", "MGEA5", "MGST3", "MICU2", "MIGA1", "MINDY3", "MIPEP", "MMAB", "MPP2", "MRPL58", "MSI2", "MSMO1", "MTAP", "MTCH1", "MTMR6", "MTO1", "MTOR", "MTR", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA40", "NAGLU", "NAMPT", "NAT10", "NCAPD3", "NCSTN", "ND1", "NDC1", "NDUFA13", "NDUFA8", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEDD4", "NEDD4L", "NEFL", "NES", "NLN", "NNT", "NPC1", "NPC2", "NPEPPS", "NRDC", "NRP1", "NSD2", "NSMCE2", "NT5C2", "NT5C3B", "NUCB1", "NUCB2", "NUDT16", "NUP160", "NUP188", "NUP214", "NUP54", "NUP88", "NUP93", "NXN", "OCRL", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL8", "OSBPL9", "OTUB1", "OTUD7B", "OXA1L", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "PABPC1", "PARP2", "PATL1", "PCYOX1", "PDCD5", "PDHB", "PDK1", "PDK3", "PDSS1", "PEX19", "PGRMC1", "PGRMC2", "PHB2", "PIK3R2", "PITRM1", "PKP2", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLOD3", "PLXNB2", "PMPCA", "PNPLA8", "POLD1", "POLDIP2", "POLE", "POMGNT2", "PON2", "POR", "PPAT", "PPME1", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP2R5E", "PPT1", "PRCP", "PREPL", "PRKAA2", "PRKDC", "PRKRA", "PRMT5", "PRMT9", "PRPF8", "PSAP", "PSMB1", "PSMB2", "PSMB6", "PTGES2", "PTGES3", "PTPRF", "QSOX2", "QTRT2", "RAB11B", "RABL3", "RAD23A", "RANBP2", "RANGRF", "RAPGEF2", "RBM10", "RBM3", "RBM4", "RBM7", "RCN2", "RECQL", "REPS1", "RER1", "RETSAT", "RHBDD2", "RPN1", "RPN2", "RPS6KA1", "RRM2", "SACM1L", "SC5D", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCPEP1", "SDCBP", "SDF4", "SDHB", "SEC11A", "SEC61A1", "SEC63", "SENP3", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGK3", "SHCBP1", "SHMT1", "SIGMAR1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC2A1", "SLC35A4", "SLC35B2", "SLC39A14", "SLC4A7", "SLC7A1", "SLIT2", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMYD3", "SMYD4", "SNU13", "SNW1", "SNX27", "SOAT1", "SORT1", "SPNS1", "SPTLC1", "SPTLC2", "SQLE", "SRPK2", "SRSF3", "STAMBP", "STARD3", "STT3A", "STT3B", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "SULT2A1", "SUN1", "SUN2", "SURF4", "SUZ12", "TAF15", "TAF6L", "TAOK1", "TAP1", "TAP2", "TARS2", "TBC1D9B", "TECR", "TERF2", "TEX264", "TFB2M", "THRAP3", "TIA1", "TIAL1", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM8B", "TIMM9", "TM7SF2", "TMCO1", "TMEM192", "TMEM201", "TMLHE", "TMTC3", "TMX2", "TNPO1", "TOMM20", "TOMM22", "TOR1AIP2", "TPP1", "TRA2B", "TRAM1", "TRMT1L", "TRMU", "TSG101", "TSPO", "TTYH3", "TUBB", "TUBB4A", "TXNDC12", "TYSND1", "U2AF1", "U2AF2", "UNC119B", "UQCR10", "UQCRC1", "USP15", "USP4", "USP47", "USP7", "USP9X", "UXT", "VAMP7", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VMP1", "WDR48", "WFS1", "XPO4", "XPO5", "XPO6", "YBX1", "YKT6", "YTHDC1", "YTHDC2", "ZADH2", "ZC3HAV1", "ZMPSTE24", "ZNF207"]} \ No newline at end of file diff --git a/msigdb_hp/advanced/idx2term.json b/msigdb_hp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..727268a17814c714500805a0548349f164520499 --- /dev/null +++ b/msigdb_hp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Cognitive impairment", "1": "Mental deterioration", "2": "Dementia", "3": "Dysphagia", "4": "Contractures of the joints of the upper limbs", "5": "Abnormal vertebral morphology", "6": "Abnormal form of the vertebral bodies", "7": "Joint stiffness", "8": "Muscle abnormality related to mitochondrial dysfunction", "9": "Optic disc pallor"} \ No newline at end of file diff --git a/msigdb_hp/advanced/plot_0.png b/msigdb_hp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..67be3f97af34b778ae929770096725bfcc5e1dfc --- /dev/null +++ b/msigdb_hp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:81fbaf864e8cf426966dbc45c636fbcc0d6de78ddaf9bfe0a4d69c9f699fc729 +size 222320 diff --git a/msigdb_hp/advanced/plot_1.png b/msigdb_hp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..58cde87ace425097108f6824ae6de78e94398157 --- /dev/null +++ b/msigdb_hp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6520b92ec198f049999f1c479d7ea9fbfc714e49560b7217a378c338f4348e41 +size 212645 diff --git a/msigdb_hp/advanced/plot_2.png b/msigdb_hp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..dad70fa912ee24427cd0853a9ba54545a0c036c6 --- /dev/null +++ b/msigdb_hp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b1e712b87cbb3979008f9cc75c80f9b63021daf10005d82aaa4ad3dbd1e94b98 +size 207681 diff --git a/msigdb_hp/advanced/plot_3.png b/msigdb_hp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..bf290dc780bad33cff276eef3cf8896c2bff1c6c --- /dev/null +++ b/msigdb_hp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3ad6892618d22766395470127f0e6af0270f453bcaebe9d9809ab7f49ddb35d5 +size 213526 diff --git a/msigdb_hp/advanced/plot_4.png b/msigdb_hp/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..fa8d4a68821dee8199e4ec112a31b9114aeddff0 --- /dev/null +++ b/msigdb_hp/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:de0c0c49a6486e3410bae4476a0c5443648eacafadfb7b09f897c80c59ee917a +size 217444 diff --git a/msigdb_hp/advanced/plot_5.png b/msigdb_hp/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..5302e85d198b6ba8f326d93f44e76a8a9971b5c5 --- /dev/null +++ b/msigdb_hp/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:073a86f73a98ba107978ebcdcecf1ff34157d45cfda028e82d81e3e806eda275 +size 216823 diff --git a/msigdb_hp/advanced/plot_6.png b/msigdb_hp/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..8cecaef85d00cd0b06e34d1f579fa0c503e0f565 --- /dev/null +++ b/msigdb_hp/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cfcc50341a6bb2dcbf6b69b2a6eeb0ae60de0519019bab1e34fa70ffedba91b4 +size 213022 diff --git a/msigdb_hp/advanced/plot_7.png b/msigdb_hp/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..f2663676019a86f420fb87163a1b19fccd41774d --- /dev/null +++ b/msigdb_hp/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7c8786e7a87afdd4061b260aeaaa854a7f50e33fc3e61cca2442e8d37344f310 +size 207053 diff --git a/msigdb_hp/advanced/plot_8.png b/msigdb_hp/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..49e476d4d0bb9321ccf1b7f6a13708c570dbb9e7 --- /dev/null +++ b/msigdb_hp/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:88871f5be14cdf17e664a991ed44e459a5a0ee6cbf9f6bf7befa03beda3baabf +size 212456 diff --git a/msigdb_hp/advanced/plot_9.png b/msigdb_hp/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..bead4548e9afeac9b7598e5ca5d2b521a543e104 --- /dev/null +++ b/msigdb_hp/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:98ef255795773a6f842903d3da7d20059e7f680ff457662316e4020a5a6c5327 +size 205933 diff --git a/msigdb_hp/basic/idx2term.json b/msigdb_hp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c53dedf5315d668a3b6bc3e1e553678dc43114cd --- /dev/null +++ b/msigdb_hp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Cognitive impairment", "1": "Mental deterioration", "2": "Dementia", "3": "Dysphagia", "4": "Contractures of the joints of the upper limbs", "5": "Abnormal vertebral morphology", "6": "Abnormal form of the vertebral bodies", "7": "Joint stiffness", "8": "Muscle abnormality related to mitochondrial dysfunction", "9": "Optic disc pallor", "10": "Increased serum lactate", "11": "Abnormal vascular physiology", "12": "Abnormality of the cerebrospinal fluid", "13": "Abnormal esophagus physiology", "14": "Visual loss", "15": "Abnormal heart valve morphology", "16": "Abnormality of head blood vessel", "17": "Abnormality of the optic nerve", "18": "Corneal opacity", "19": "Abnormal cellular phenotype", "20": "Sensorimotor neuropathy", "21": "Abnormal muscle fiber morphology", "22": "Abnormality of the mitochondrion", "23": "Functional abnormality of the gastrointestinal tract", "24": "Abnormal retinal artery morphology", "25": "Abnormal circulating lipid concentration", "26": "Talipes equinovarus", "27": "Limitation of joint mobility", "28": "Arthritis", "29": "Abnormality of coordination", "30": "Skin nodule", "31": "Vascular skin abnormality", "32": "Ventricular arrhythmia", "33": "Heterogeneous", "34": "Abnormal activity of mitochondrial respiratory chain", "35": "Abnormality of extrapyramidal motor function", "36": "Localized skin lesion", "37": "Increased susceptibility to fractures", "38": "Variable expressivity", "39": "Abnormality of femur morphology", "40": "Decreased activity of mitochondrial complex i", "41": "Pain", "42": "Limb joint contracture", "43": "Biliary tract abnormality", "44": "Mitochondrial myopathy", "45": "Abnormality of pulmonary circulation", "46": "Abnormal myocardium morphology", "47": "Skin ulcer", "48": "Exercise intolerance", "49": "Abnormal joint morphology"} \ No newline at end of file diff --git a/msigdb_hp/basic/plot_0.png b/msigdb_hp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..cf244e66379d5fbc645a6a3a95f80d4497a28a82 --- /dev/null +++ b/msigdb_hp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6a74b1031c4254bd9d33da7f7a2997e2903d6114164846f14327eb81287e5868 +size 145662 diff --git a/msigdb_hp/basic/plot_1.png b/msigdb_hp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..5ae239b94ffd40972069fedb4a2dd112ff3539bc --- /dev/null +++ b/msigdb_hp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:817777c39aba96de0ec6e8f9c5971e31889631436f1c02c365362665aca15710 +size 141756 diff --git a/msigdb_hp/basic/plot_10.png b/msigdb_hp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..902a4d5aaab28f8a0ab13adb4475fb9cc5d0c117 --- /dev/null +++ b/msigdb_hp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dda034e20bdcaf7568586d96582affbc7414de9630d80a012b0fcc0d367ebed4 +size 148005 diff --git a/msigdb_hp/basic/plot_11.png b/msigdb_hp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..9abd50e8ca13f34889654f50a29d75a593af799d --- /dev/null +++ b/msigdb_hp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7d9ce57b2ba59b50a452061219ac7acb711af70053035315870db55deae436ca +size 146975 diff --git a/msigdb_hp/basic/plot_12.png b/msigdb_hp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..1422092a18cbdb516927487e5838d7a21fcfcc9a --- /dev/null +++ b/msigdb_hp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:da5c9d24611124348329e81b379889fb0b5ba078ebfcf01dc545804ed098bfe0 +size 153415 diff --git a/msigdb_hp/basic/plot_13.png b/msigdb_hp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..353a33321b33f2207e1de95b245302a07ffb7ea2 --- /dev/null +++ b/msigdb_hp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dae8b36a31f6c361c56f7ca128770fcf9e6438fab4cb91a857ca56d338f152d9 +size 151583 diff --git a/msigdb_hp/basic/plot_14.png b/msigdb_hp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..b8ba82e8e95aba280604502e844c868b709a2654 --- /dev/null +++ b/msigdb_hp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8a2216dd3174aeb8f2f65ea36fb05407d0e8a896d3f5d12590ed62d027ea951a +size 137906 diff --git a/msigdb_hp/basic/plot_15.png b/msigdb_hp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..f3d537451909ccb9230a7328f5a953d8d36a40ef --- /dev/null +++ b/msigdb_hp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bff5342a0a1793f154911b8e39e5bc6afc6b2ce5ca17d8de51c946ad22219efa +size 154220 diff --git a/msigdb_hp/basic/plot_16.png b/msigdb_hp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..4468bd7eaa6c93882e8c9068dfb97346717d0845 --- /dev/null +++ b/msigdb_hp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:633fecccdeee9bc0ffaea211a98c0ecdacdf427b7277f50206b291b99825f4b7 +size 145063 diff --git a/msigdb_hp/basic/plot_17.png b/msigdb_hp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..90eed3c47604a91a4ca3d1682501ba9c9b0a2912 --- /dev/null +++ b/msigdb_hp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:adedb168948e3cfdc75148a420733111ebb1b2e1f602c5a703cac21b2b53b0a3 +size 149168 diff --git a/msigdb_hp/basic/plot_18.png b/msigdb_hp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..773c39b72e06a69141dc33000b72f1373609226f --- /dev/null +++ b/msigdb_hp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8e93c6c0a0e677778efdbf6e12ffc39b896205572d7a68076482d40ba16fc00b +size 145190 diff --git a/msigdb_hp/basic/plot_19.png b/msigdb_hp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..c31b35b394084717ab29f23384c150fa7549f2a6 --- /dev/null +++ b/msigdb_hp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:909e6beb214210bc3b1d97528a5cf2e132dbe68246a630dd64f14fd1beb9c1c5 +size 145670 diff --git a/msigdb_hp/basic/plot_2.png b/msigdb_hp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..1fcb52698d7899d6076995d7a7c095802f72a87b --- /dev/null +++ b/msigdb_hp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d8fb50b0fb105726052b0cd8d218c7fde686969e8ff1bff1665aa5295d99e074 +size 136239 diff --git a/msigdb_hp/basic/plot_20.png b/msigdb_hp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..248da601af7c42e7f2f8cd31f232831beaf9c4d6 --- /dev/null +++ b/msigdb_hp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1cf2f7df0e1017186f27c195248d05c45eacefbedd395c88fa43e5b7493a2db4 +size 143978 diff --git a/msigdb_hp/basic/plot_21.png b/msigdb_hp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..e44ee501383abc7e938bdb67592084c8fca6ef66 --- /dev/null +++ b/msigdb_hp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a9fdefa089aab03e616cd7115c1816bbc5f5e5671da0848e9be23d6e76b97730 +size 144380 diff --git a/msigdb_hp/basic/plot_22.png b/msigdb_hp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..603d63a1ef7f44b03b8e898af950b339c5097356 --- /dev/null +++ b/msigdb_hp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:24a5493a65846fac0b2b0727f242a32ab1ef7686ac6f07f0d38df52d402e34ed +size 149848 diff --git a/msigdb_hp/basic/plot_23.png b/msigdb_hp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..fcd89dfca07b6d6470de87efd11bdc79fc45dbf1 --- /dev/null +++ b/msigdb_hp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:85d96d75ec664ba951a3f39b536342f13dd17f70feea6d736126d2c0225b9c09 +size 152133 diff --git a/msigdb_hp/basic/plot_24.png b/msigdb_hp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..7d867f6109cda505a1528aae8194d6bf5c0a65b6 --- /dev/null +++ b/msigdb_hp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b763b231fb69fc579307d4f9d5c70c4defcdc2e97f3bca709b4e6111586da084 +size 146407 diff --git a/msigdb_hp/basic/plot_25.png b/msigdb_hp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..3511bb658780821e60c41dde9d499e60a3a1e1ac --- /dev/null +++ b/msigdb_hp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fa469d0cd083ea19a3e7c5b6df55e5ff335697ea69c70a7b419b9c4e43348f1f +size 154672 diff --git a/msigdb_hp/basic/plot_26.png b/msigdb_hp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..5edcf8dd4a14e194661848556a08efde299c78ac --- /dev/null +++ b/msigdb_hp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:071a39b289f075f637cad7883ba88e0cceadb45d580944c2c88221fc2b47b982 +size 146452 diff --git a/msigdb_hp/basic/plot_27.png b/msigdb_hp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..c16d2d7b39328d042984e7ada16b7bde2d9fe2ea --- /dev/null +++ b/msigdb_hp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cdc1fe57735a3464f3e6fdd623f541808fd13fc6cf59c6e034a0b2ebe84708c5 +size 145645 diff --git a/msigdb_hp/basic/plot_28.png b/msigdb_hp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..775616b19f82dfdd718953430e867fe04c5c9bc8 --- /dev/null +++ b/msigdb_hp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f3576397137cd1118f58c59b3a80e2506e51200685d24f183e492f67a983aeee +size 139754 diff --git a/msigdb_hp/basic/plot_29.png b/msigdb_hp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..d2f91f6231961740603d56bd64cb2a3b19d224cd --- /dev/null +++ b/msigdb_hp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9aceff17fd898d19bc746a516e6c2d8d0a8a89aba3191c0874b042e48d7930d8 +size 146037 diff --git a/msigdb_hp/basic/plot_3.png b/msigdb_hp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..9e9cfb1d789ad5a37fb20ab296cb87ae31406d6f --- /dev/null +++ b/msigdb_hp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e842d9a3b277309b8c710869bb1d98960bc368845d8f9f85ebd9ae7fd84c6d85 +size 142988 diff --git a/msigdb_hp/basic/plot_30.png b/msigdb_hp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..f529886b0ebe9047dd4587bb6827a0a86c5ad4e6 --- /dev/null +++ b/msigdb_hp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:129ef89f106640bc9c73b9dce918a4ce44bb778a15457152494b4562d7a1cb17 +size 135240 diff --git a/msigdb_hp/basic/plot_31.png b/msigdb_hp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..d5a997fb19a83fe8105421deb648370b477dde39 --- /dev/null +++ b/msigdb_hp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8cb0926321f7c44b220b498def74f3d231b4568666ab746534f3e75ae3bcf9f9 +size 150356 diff --git a/msigdb_hp/basic/plot_32.png b/msigdb_hp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..8e922e8e7ef92ac53a9ac777303aadec9c28964c --- /dev/null +++ b/msigdb_hp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2fcb2227fef6a20b3775cfb2826a6f2ad3184bf521ca484b6a413a714d93753f +size 133836 diff --git a/msigdb_hp/basic/plot_33.png b/msigdb_hp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..c778017ed47bd3c0a229f456f212d0ecf0dc6437 --- /dev/null +++ b/msigdb_hp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a0004c2318f30dd9537962f880a30e27e7f427954226be8e988047a76411f6ba +size 139048 diff --git a/msigdb_hp/basic/plot_34.png b/msigdb_hp/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..8a995afcb8216bf7cc43828ed62e485a8f867062 --- /dev/null +++ b/msigdb_hp/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:038162dc343524fc113e1002eb4b84e4a0a590d15ccb13eb27718844be5ec1f0 +size 156355 diff --git a/msigdb_hp/basic/plot_35.png b/msigdb_hp/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..5fea19ac987c2512861f81d4f2045cc8bda1b219 --- /dev/null +++ b/msigdb_hp/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fddf275c4049614aa5020fd7d2295840287270009d31de6d99059baf6e134b7a +size 154843 diff --git a/msigdb_hp/basic/plot_36.png b/msigdb_hp/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..1b0e3aba2535225d946c5a12fb6f16bc391c03d3 --- /dev/null +++ b/msigdb_hp/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9770abb58bac378884fdc18da6ff52eb5c0ff2ccbf6ba0e9f6c7f9d2656ded88 +size 145945 diff --git a/msigdb_hp/basic/plot_37.png b/msigdb_hp/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..65bf0db39ffbff3764b97342a4bbde5299c2de9e --- /dev/null +++ b/msigdb_hp/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9a8ee57e9a36a2c7c98f17137dc8a59bc388f82a9933fdc638b3fd5e62e0bb20 +size 147416 diff --git a/msigdb_hp/basic/plot_38.png b/msigdb_hp/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..0e5e9ba858620af1775440773dab82daaa9ee136 --- /dev/null +++ b/msigdb_hp/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:366d8e2074d081ad8a6aa79d45f276bb468c47701b6831b5e90404bbb533a297 +size 147608 diff --git a/msigdb_hp/basic/plot_39.png b/msigdb_hp/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..40b3a83e40ef8deb98c7660c6ec8a7c8a6d35db8 --- /dev/null +++ b/msigdb_hp/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7daf4861ad62a9fded5dc7d9e857f3084c42abed5b2bcae1ec8db2b06c17ae7e +size 150678 diff --git a/msigdb_hp/basic/plot_4.png b/msigdb_hp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..0e0a994ece426ec823b51ed4b6e93973424ffd70 --- /dev/null +++ b/msigdb_hp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2b3ccb9a4e6070a23162b95da216cd17c322d0d625f2beba86f3b293e0a92a85 +size 148906 diff --git a/msigdb_hp/basic/plot_40.png b/msigdb_hp/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..440b8eec7c62b3c1691e40867ee6b95c583d4c86 --- /dev/null +++ b/msigdb_hp/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2bf1d353443c5f7561c909baad392c656048945e1f30b565440518522946ee14 +size 149301 diff --git a/msigdb_hp/basic/plot_41.png b/msigdb_hp/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..a3fdb6deaba629b2efd3d0f23e23ee614aec7079 --- /dev/null +++ b/msigdb_hp/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5178fadab54126724eeef78fe70be2d7b4d2c66c4f7ddc53a5da57c11add7cea +size 136271 diff --git a/msigdb_hp/basic/plot_42.png b/msigdb_hp/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..8050ea093e75414ffbd4fd4a68d31476ef1677ee --- /dev/null +++ b/msigdb_hp/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2d6ab4e5bb2d705c4684752491444e6bb56bb48903be3de16b26d40917a15640 +size 146891 diff --git a/msigdb_hp/basic/plot_43.png b/msigdb_hp/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..f0e626c527a62dfd38b659c11d8ac71f80a3c104 --- /dev/null +++ b/msigdb_hp/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c00091b3208aa27e2479ddbb26b05f438bc420131378559e1fc29562724300a4 +size 143059 diff --git a/msigdb_hp/basic/plot_44.png b/msigdb_hp/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..c9326e0334829022c5d37019997f6fe751a8473e --- /dev/null +++ b/msigdb_hp/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:806d88797436d16e50ec2d317b6d9fd469fb495ee17e1b9b5719e5f6bb4edb9f +size 143287 diff --git a/msigdb_hp/basic/plot_45.png b/msigdb_hp/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..211848e4ffe089571eea21eb7e4a0b90e1438631 --- /dev/null +++ b/msigdb_hp/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a6756eac86faba1f1a38fffb2cc2048163093aee3e189b96949f3909da53802e +size 148811 diff --git a/msigdb_hp/basic/plot_46.png b/msigdb_hp/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..9add5a104f27e51b98c68782cf34abafa835253b --- /dev/null +++ b/msigdb_hp/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:182ce54cfe92456e6fe5ad80d08c68d23590ab8030f5155a43076d868dc58234 +size 151615 diff --git a/msigdb_hp/basic/plot_47.png b/msigdb_hp/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..75dfdf853175219331a095777bd34beb21e55b5b --- /dev/null +++ b/msigdb_hp/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6d20adb43145f9fe10154f11549b5df11c82b520e99f000787375b53d19338d3 +size 134433 diff --git a/msigdb_hp/basic/plot_48.png b/msigdb_hp/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..dc203d8c199811f8e02f84d00e3d82a6faef7d74 --- /dev/null +++ b/msigdb_hp/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:34e00d6d43d6bedd5a42d29805c92f436d7ddea7feb74c634a8ef6ee476f2aaf +size 141183 diff --git a/msigdb_hp/basic/plot_49.png b/msigdb_hp/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..43a9ba9a1c215a7f2d083452643005cd53e4ee6f --- /dev/null +++ b/msigdb_hp/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9aa73539cd004e530e0abd5251511017c98206fb76a969644adb2ad68839a859 +size 145527 diff --git a/msigdb_hp/basic/plot_5.png b/msigdb_hp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..9c3026a68d015d0462c0df8a30454b45ce36a4ad --- /dev/null +++ b/msigdb_hp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cbf83efbc5f6addb3a02e7c75f2affeb4d0c71edcc0b5a96b5707b4807793028 +size 151630 diff --git a/msigdb_hp/basic/plot_6.png b/msigdb_hp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..4c1eb2b4bbd8a1c58f7b37206fcce88cba1111a9 --- /dev/null +++ b/msigdb_hp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f5492d7f42fc8d7cf12356a3dde1b8b4dfe490a0d9c3cfc7f44f291c9fc403d2 +size 153050 diff --git a/msigdb_hp/basic/plot_7.png b/msigdb_hp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..543d894d4664e81b572dc5e4ff3c903c633ba17e --- /dev/null +++ b/msigdb_hp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d7a153a305d7daff63e610eee305fde97d8fc07272649172e8bee91ecf67abcd +size 137855 diff --git a/msigdb_hp/basic/plot_8.png b/msigdb_hp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..9c1d083ed3b358de75545a7165c834318b07773d --- /dev/null +++ b/msigdb_hp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a3cc9b5fad2b189a1060d49efff0a4ebc4cb0fefb706a652c833930ec93c9c40 +size 150495 diff --git a/msigdb_hp/basic/plot_9.png b/msigdb_hp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..19c7c01065543cbb50777922a66f2dc1b3ac11e8 --- /dev/null +++ b/msigdb_hp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c03b6f19a5de602b04b9f038cd5b41b95d3ce9802c0dfec27056af263c0be1d2 +size 138495 diff --git a/msigdb_hp/consensus.joblib b/msigdb_hp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..466a3f276185a7ca353d206868cae377db218946 --- /dev/null +++ b/msigdb_hp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:03f679418be49fde1b150b41c08d91678c276c231c82c9c0ae82b2e91d234c87 +size 585546 diff --git a/msigdb_hp/df_merge.tsv b/msigdb_hp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1656e04a44720d8d6a6fce74b6e5d1cef75c9c2b --- /dev/null +++ b/msigdb_hp/df_merge.tsv @@ -0,0 +1,249 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Cognitive impairment 50 176 4.333434020881012 1.4680129079014392e-05 40.38834951456311 166.01456310679612 0.9678903819313606 0.4602309002251459 12.35477425089026 15.27402711863426 1.6121748345734526 0.4202585511538368 2.275678135027805e-05 0.0002924350874714 2.9824428814879423e-05 0.0001035387840341 7.852608094557432e-08 +Mental deterioration 34 100 4.164688220613184 3.117783272266195e-05 26.16990291262136 97.51699029126212 1.0638646072845834 0.3178098854339388 8.217921866043707 8.355116022963852 1.9487627742005753 0.3762024781602087 5.547105858220812e-06 0.0012377122057562 2.853187837438928e-05 3.4121815210897086e-05 1.1133628154730265e-07 +Dementia 25 58 3.7329375027682743 0.0001892595670041 17.021844660194176 58.19174757281554 0.9978727756866732 0.3214313161707923 5.814027938449679 5.568168011495494 1.793982160512653 0.3770196158976925 2.8019086226116827e-05 0.0293962749000691 0.0022367873472097 0.0001286814110505 6.720458184047846e-07 +Dysphagia 32 137 3.711310935793693 0.0002061886421775 26.58252427184466 132.13349514563106 0.525484494447878 0.6234130914808526 8.355016250174085 12.686440449515484 0.9112834521434876 0.3703513369566691 0.0119834213346988 0.0305140236078737 0.0245049309725114 0.006944546501678 0.0049968719396101 +Contractures of the joints of the upper limbs 19 73 3.6657147082546655 0.0002466487728789 15.5873786407767 70.82038834951456 0.961917368584866 0.453560490665382 5.296970733704175 9.19591360516456 0.9682537043334576 0.378553967263451 0.0091625383196232 0.0006942263533444 0.0014436735130772 0.0030014200869646 0.0055077405410857 +Abnormal vertebral morphology 41 112 3.662872022611669 0.00024940315855 25.18446601941747 107.1383495145631 0.7050611944944222 0.5078087978506296 8.434496402822974 10.278065304429203 1.0858158093436174 0.3796440707216367 0.0172610882722085 0.0044603241769421 0.001116293772174 0.0115954751590373 3.2602037607196034e-05 +Abnormal form of the vertebral bodies 34 88 3.661721407139568 0.0002505262139307 19.968446601941743 83.88349514563107 0.6644002102675167 0.5345165392282933 7.187939907318809 8.37593753149639 0.9881357365384656 0.3722270618536288 0.0844393000096224 0.0068683859679104 0.0337698983301791 0.0793833993194665 0.0001575827621432 +Joint stiffness 18 56 3.647463565679012 0.0002648418517605 12.87864077669903 55.95873786407767 0.3271163739047257 0.5669766886577318 5.4865086159860095 5.123309227065953 0.9871597951660472 0.3442632187865738 0.011661547978683 0.0039003874446117 0.0095229572911991 0.0155223568513004 0.0002172697746726 +Muscle abnormality related to mitochondrial dysfunction 14 37 3.6097644994988376 0.0003064751249783 11.12378640776699 35.58252427184466 0.9791864828781052 0.3365990386989574 4.6259837298613 4.333263242301439 1.4740065920951253 0.3430734831138388 8.400529664410988e-05 0.00029486717559 0.0004567644770011 0.0010864364912465 4.420299325281492e-07 +Optic disc pallor 20 50 3.476971496523278 0.0005071117254513 14.480582524271844 48.592233009708735 1.02733963234224 0.3801436604957769 5.692535706296588 6.181615230530596 1.3595924408188145 0.3692839687174071 0.0528886029690114 0.1185798153291669 0.1157235318918368 0.0757785059975643 0.000243555456147 +Increased serum lactate 28 107 3.465404645529462 0.0005294342344712 28.99514563106796 103.9126213592233 0.2156320103365802 0.4835633979758786 13.01418105275692 9.239117761559864 1.4606133548257267 0.3784654233889921 2.6501692937831168e-05 0.0526657559172975 0.0274663163708318 0.0003154104448529 4.057695015987638e-09 +Abnormal vascular physiology 17 56 3.4602546733310886 0.0005396647274031 12.74757281553398 50.021844660194176 0.816183607478715 0.4136638745601454 4.907827009322534 5.622165606934028 1.2216480011219424 0.371091913776798 0.0032016048003911 0.0519267383076168 0.006817193925808 0.0095294704033757 0.001757286667079 +Abnormality of the cerebrospinal fluid 45 157 3.4541524211283656 0.0005520252860931 33.26456310679612 139.65776699029126 0.6333875809946081 0.5372237787257415 11.267291201647208 15.193792257662585 1.1555525507377646 0.3935007134599857 0.0421492401009453 0.015162244486392 0.1116779959766435 0.1364566188854092 0.0004950733028188 +Abnormal esophagus physiology 52 233 3.4333598100960767 0.0005961504013742 42.987864077669904 218.53155339805824 0.151647115905167 0.8155245796554588 13.361927812082786 20.492159867460444 0.5558248064995885 0.2773157815850654 0.0070224005569368 0.0649946788296162 0.1194837062416312 0.0161851351109064 0.0014273723248497 +Visual loss 15 52 3.403378459197383 0.000665580179531 12.189320388349516 49.779126213592235 0.7709512625515322 0.4025114627500821 4.5744204921606055 5.175300864908489 1.242827263568942 0.3662286004483653 0.071169986501166 0.0408125099476932 0.0670588556929843 0.0373736184953509 0.0037865386779487 +Abnormal heart valve morphology 26 82 3.3906019016941435 0.0006973932273699 17.83252427184466 77.13106796116504 0.4699099631595928 0.6096529829544438 6.02733340682127 8.717091003223958 0.8450929313560487 0.3556463006581863 0.0070131132853743 0.13795486567134 0.2578342108456208 0.0578093627085774 0.0022286511437342 +Abnormality of head blood vessel 11 25 3.360892324381928 0.0007769110660456 7.512135922330097 24.881067961165048 0.5951213621611695 0.2501622891395578 2.541375726543966 2.628804376839775 1.8399520883426277 0.3043503409762604 0.0002446120391689 0.0348230103466341 0.0027897058150509 0.0153040129106345 2.538972545725035e-05 +Abnormality of the optic nerve 74 262 3.359834247529889 0.0007798924770188 55.26699029126213 243.98300970873785 0.3330545875114519 0.7420961441999799 15.8565039079985 26.975306987282984 0.8419720138567378 0.3446258953426701 0.0152424239439871 0.0385220463165193 0.3084082856397689 0.0478130979053001 0.0002590114291771 +Corneal opacity 21 59 3.3588618321330337 0.0007826418764589 15.480582524271844 53.95631067961165 0.9517965339960472 0.3644495779961974 5.277458167452316 6.791845051563607 1.5225460520633525 0.3686110256368129 0.0170610217215859 0.0651780475785867 0.283187038525853 0.1799833517476273 0.0021177009393639 +Abnormal cellular phenotype 45 199 3.305127708866551 0.0009493313218973 39.61407766990291 185.5461165048544 0.5974508379603953 0.5924097878960474 13.622479133459526 17.10902530988799 1.1142688852015548 0.3995331163327372 5.882535075700974e-05 0.0001942678635167 0.0009078998603743 0.0001155333997653 2.075307106260708e-05 +Sensorimotor neuropathy 9 30 3.250198254628381 0.0011532458075864 8.980582524271844 31.118932038834952 1.3016328701661894 0.3009249972125085 3.646997920951252 3.5836645053134393 1.2437208862143418 0.3260038325488978 0.0457331460780527 0.0048225524960019 0.0048690104254232 0.0279194128393474 0.001939589155648 +Abnormal muscle fiber morphology 19 70 3.21153483507353 0.0013202796268212 17.78640776699029 68.04126213592232 1.263675841483234 0.3649599499596623 6.500784844979595 6.6307423444197315 1.1691802531751734 0.3853191125649093 0.001847661486362 0.0001263386976362 0.0001764914464403 0.0005749054399793 0.000103125756192 +Abnormality of the mitochondrion 24 93 3.206687165592355 0.0013427292626997 24.216019417475728 91.8883495145631 0.797381253925538 0.4153343301115782 10.704523845407817 8.200885590005743 1.4941762160347407 0.3812617801525748 0.0001748963192159 0.0001307121217589 0.0010427383426084 0.0001648411058239 1.149785766029405e-05 +Functional abnormality of the gastrointestinal tract 61 288 3.20525352472662 0.001349435641025 51.90291262135922 272.59466019417476 0.1117218875466218 0.8576022020310513 15.629518104434023 25.7113036724126 0.4945233571076165 0.2551389014479654 0.0100838513829582 0.0704457790081592 0.1139326982438867 0.0257173792965149 0.0020006198961018 +Abnormal retinal artery morphology 10 22 3.1994080271021645 0.001377101182032 6.985436893203883 21.733009708737864 0.6882820766413594 0.2247118762866906 2.318097134221824 2.0518941450352677 1.8438290687413053 0.2835525492265039 6.536170361222628e-05 0.0248568883498602 0.0014196759684318 0.0072215435094453 2.145591648835698e-05 +Abnormal circulating lipid concentration 22 80 3.189365373969269 0.0014258553525789 21.0995145631068 75.44417475728156 1.321442689138656 0.3287247628796158 8.33534407984455 6.5596064623065375 1.4065018349702674 0.365722219395451 0.0233441601151645 0.0015167671735356 0.0015262699690601 0.0259997606501871 0.0002759800508016 +Talipes equinovarus 24 81 3.179201663104122 0.0014768130649569 17.890776699029125 76.62135922330097 0.5495068800315274 0.5880189289841166 6.331475723212702 10.674910704116524 0.8250227780407152 0.350320151193932 0.0220062142916572 0.3443282275566168 0.4406224335053858 0.1535453791594572 0.0004337161244851 +Limitation of joint mobility 27 103 3.153003902796006 0.0016159964629494 21.060679611650485 97.9368932038835 0.3085934150476662 0.6495028096480517 7.742751544501191 10.216391648179064 0.8329388631334591 0.334643383369233 0.0398886489789686 0.0100581420106454 0.049358292685713 0.033176791757977 0.0006756013524132 +Arthritis 12 43 3.118584738146869 0.0018172187883684 10.45631067961165 41.12864077669903 0.9299077951686036 0.3844403642845474 3.7326340917241647 4.351147052994631 1.200139433310656 0.3557501916131977 0.0106655790068841 0.0981576694070633 0.0896229662502218 0.1244208710101112 0.0021820294106423 +Abnormality of coordination 61 332 3.117213906889164 0.0018256905106737 65.05339805825243 312.07766990291265 0.3537206479527984 0.7134221988982268 20.398983010696288 29.808593053234937 0.9921840157004412 0.3756105558441653 0.0004973117236806 0.0408684679706217 0.025213952917537 0.0041828105926183 5.499891084611263e-05 +Skin nodule 7 21 3.09427236833938 0.0019729626952045 6.070388349514563 21.26456310679612 0.7442674094202993 0.3924071478475022 2.7239314899251803 2.029014432281319 1.0984628042075235 0.3129154853478004 0.0017960344551681 0.0380696669646128 0.1267862934099702 0.0676165417704692 0.0109011131386191 +Vascular skin abnormality 30 125 3.089957937562823 0.0020018484310886 24.946601941747577 116.29611650485435 0.7757412099244599 0.4861695283888829 8.070806982353375 12.284834935174542 1.190653202647226 0.3932244292288712 0.004375822693655 0.0917366308629353 0.0214353467047257 0.0119345767999183 0.0008902344262955 +Ventricular arrhythmia 14 43 3.0896006108422416 0.0020042581045813 10.0 36.96601941747573 1.0415384316890377 0.3677574027458479 3.8522468541414527 4.8022861343455805 1.0152201826292362 0.3231502492090489 0.0228801367862345 0.0876325329480415 0.0172354677097154 0.0117065019059818 0.0098156715029369 +Heterogeneous 12 47 3.077998480611757 0.0020839597760426 10.235436893203884 42.58009708737864 0.5995354724013603 0.4531415918363276 4.134323127398932 5.0637577656341985 1.0306945905630256 0.3367867805298957 0.039629174359154 0.029947979425984 0.0465586731094984 0.0522359869494767 0.0729574196702931 +Abnormal activity of mitochondrial respiratory chain 20 54 3.0770174788965243 0.0020908304040312 14.847087378640778 52.86407766990291 0.7821137838412346 0.382257667326437 7.203923975365814 5.31995427327111 1.5049815702887546 0.3635380021892623 0.0010473306589933 0.0010411100702788 0.0020569485401092 0.0017967215859439 3.354774772855265e-05 +Abnormality of extrapyramidal motor function 18 75 3.054771734159477 0.0022523187516025 17.723300970873787 74.23058252427184 0.6611914449106878 0.5008095396366101 5.517064505158221 6.985611887807198 1.1554912414277594 0.3847143245763222 0.0006286988120338 0.0177771825303302 0.0153363675909644 0.004462703425323 0.0023387817030003 +Localized skin lesion 54 230 3.036887075547787 0.0023903498675952 40.87378640776699 212.8252427184466 0.0910948881084417 0.8416447746177554 12.879900508910264 20.97255589262413 0.4825428748897505 0.2520924091555057 0.0136128018009729 0.0369111469235059 0.1819870483794151 0.0438662564889521 0.0006796001186255 +Increased susceptibility to fractures 14 59 3.035596813032289 0.0024006014043573 11.298543689320388 52.63834951456311 0.6062165983596748 0.5457625999772061 4.708049068828723 5.888757199406996 0.818710666746425 0.3467528628559314 0.0212494841854593 0.0055769350519062 0.0030749010027362 0.0095053636346543 0.0019345919105909 +Variable expressivity 14 80 3.0286382377229115 0.0024565865763777 16.655339805825243 76.72572815533981 0.9137081973948464 0.4866305980303022 6.903822328870412 7.203694993346709 1.0588933116250316 0.3878161256963057 0.006067306639635 0.0192448906093717 0.0010408251949764 0.013992988017398 0.0502540343273679 +Abnormality of femur morphology 21 74 3.027215654979471 0.0024681780277044 17.20873786407767 66.68203883495146 0.8363246416857221 0.4265359075043799 5.791282481104246 7.777760660479065 1.2398669594969238 0.3848538433547022 0.0032535339995981 0.0003574590716031 0.0030052245510116 0.0029802386086747 0.0001977388724683 +Decreased activity of mitochondrial complex i 11 36 3.0223172073454365 0.0025084753264377 9.281553398058252 33.63834951456311 0.9162605947168436 0.3572379048008119 4.7041965890170365 4.116953486956332 1.2998989973013628 0.34388058367185 0.0004997154973387 0.0019583087959773 0.0015290244076972 0.0014327621348651 4.296304877024734e-06 +Pain 36 183 3.018186336743498 0.0025429249304225 37.08009708737864 174.89563106796118 0.560521494187844 0.6082034136674831 12.418311408681989 15.731400802334642 0.9626712538875356 0.3834317739449847 0.002179553403966 0.0087453154013504 0.0075519579933677 0.0074318450855558 0.0003370717847298 +Limb joint contracture 23 104 3.0161061731970737 0.002560435875949 21.16747572815534 100.42233009708738 0.6687590042181877 0.5853612155895958 7.458858708924721 11.434332835202127 0.8235264349573469 0.3682957054317731 0.0071862841886434 0.0027423152405966 0.0073940033298519 0.004852437177014 0.0073194959674432 +Biliary tract abnormality 12 29 3.013119782187138 0.002585768343299 8.184466019417476 26.4004854368932 1.3038634098573934 0.2674323053300255 3.1080777089644696 2.335313487465734 1.3483489456318312 0.3101233364725878 0.0087264472984559 0.0391768542263283 0.0035281458113583 0.0045854934200779 0.0009608612144703 +Mitochondrial myopathy 10 28 2.9878788675407115 0.0028092087034132 9.186893203883496 28.17233009708738 0.8747125393417822 0.3473011798108487 3.936575202939786 3.974666305559559 1.3336232032537867 0.3216890657230479 0.0005638708459846 0.0267403422938185 0.0142951840993497 0.0085171031160944 3.176403402652151e-05 +Abnormality of pulmonary circulation 14 31 2.980423722364932 0.0028784991595782 8.439320388349515 28.538834951456312 0.8940347945025898 0.342085103264471 3.349932259027002 4.295622811850572 1.233599840087162 0.3264185554851845 0.0101127074293734 0.0154102901166228 0.0006224264999654 0.0157092440877508 0.0147689868730135 +Abnormal myocardium morphology 41 186 2.9674040095651497 0.0030032604289145 39.25970873786408 168.2597087378641 0.3575832300862268 0.6390291398034755 13.965214340125677 16.3501737739829 0.9922765990658236 0.3661562236284471 0.0016367817080187 0.0041839642972755 0.0081362890047421 0.0033996412556199 6.786059816832799e-06 +Skin ulcer 10 34 2.9532618601010503 0.0031443510999606 6.660194174757281 29.611650485436893 0.3066149117240137 0.5927331806895341 3.4684525467551492 3.2041629769245414 0.8556736681910342 0.3230060576991134 0.0038656850815872 0.0052183556056447 0.0053825771408227 0.0018159248066051 0.0006596002166852 +Exercise intolerance 6 32 2.9281307125563747 0.0034100665118215 7.589805825242719 32.94660194174757 0.6935647402019111 0.4794430320014746 3.6422804337959303 3.649320073231373 0.9787082553108852 0.3464451860868903 0.0045048697265846 0.0004573916663925 0.0007740006296611 0.0021288846429902 0.0676022626142099 +Abnormal joint morphology 57 288 2.914722936401714 0.0035600443992787 52.30339805825243 266.1990291262136 0.2500788863693359 0.8078491493990106 14.864197165849184 27.339633008473005 0.6288365893380027 0.3047285664472046 0.006120454026777 0.0282475097150316 0.0311603624488244 0.0158909673149864 0.0001423829307331 +Elevated pulmonary artery pressure 13 26 2.9061965659014675 0.003658515424751 7.422330097087379 24.033980582524272 0.8771466934674594 0.3206437689207037 3.083196929894625 3.78086786662344 1.283632173810104 0.3146045769490745 0.0121270542607023 0.0093752195011205 0.0002305907491292 0.0215360722135964 0.0109585410192187 +Subcutaneous nodule 6 17 2.889367842091524 0.003860172284279 5.174757281553398 17.716019417475728 0.7715929851765809 0.3892857335439222 2.3624373807533945 1.5246949972287631 1.0645096840549642 0.3076166958299045 0.0037887162809803 0.0286799036387023 0.0981876870196897 0.0424139427802885 0.0150905845261323 +Dysmetria 13 58 2.884373593050066 0.0039219317550849 14.618932038834952 55.148058252427184 0.6447099310037795 0.5301040823699991 5.464619727151339 6.3203263646610806 0.9326090127326924 0.3593910006397782 0.0087397653900743 1.0 0.3511849676405914 0.011979383486549 0.0031921827166461 +Abnormal retinal vascular morphology 13 51 2.8747164516940944 0.0040439048115143 11.550970873786408 50.40291262135922 0.374132464893944 0.4137648703700375 4.646725961814426 4.349733979382428 1.4638612584769457 0.3720428539009304 0.0116311476998962 0.1760534030430948 0.0658139566612362 0.08540418859765 0.0187378186383463 +Hypertrophic cardiomyopathy 28 116 2.871432832617573 0.0040861560821219 26.796116504854368 107.3495145631068 0.4274787301303976 0.4988726739093555 10.944572821213892 9.196568310864103 1.312724112644841 0.3809066370755179 0.0006921091835825 0.0255000660469113 0.0249402722564011 0.0014636238647962 2.0273756593858597e-06 +Abnormal bone structure 42 188 2.867530127002643 0.004136894156147 37.41747572815534 174.03398058252426 0.5052466892255619 0.6451089511590872 11.181012226303604 17.857684720378465 0.8786021869184294 0.373142151762858 0.0082262914746576 0.0007087997264993 0.003962315360242 0.0127278465033066 0.000256888599391 +Phenotypic variability 43 104 2.854934550216903 0.0043045698780967 22.339805825242717 99.4368932038835 0.8464119152872666 0.5170730885331468 8.500203764614474 8.607030207254683 1.0360918895927824 0.3938137781932724 0.0106862922738697 0.0457760313355365 0.0056488105818582 0.0179129459133912 0.0485414073654575 +Abnormal biliary tract morphology 7 26 2.8547810246125103 0.0043066511298521 7.427184466019417 23.174757281553397 1.329418499193971 0.249884151345828 2.8924137189053876 2.044064029481889 1.3393824039546371 0.2984385007787948 0.0034468330488433 0.027703186905031 0.0017650811354645 0.0017538141840637 0.0038055285280442 +Abnormality of the vasculature of the eye 18 75 2.8335534893470182 0.0046033603204134 16.27912621359223 72.06553398058253 0.403343228775578 0.4479390001832676 5.629952078086087 5.671259209870798 1.3806507490937323 0.3789287537753926 0.0117019369283679 0.3081504582131807 0.185287652132577 0.106452008846828 0.0154317918224192 +Positional foot deformity 27 103 2.811053553073225 0.0049379566227722 22.300970873786408 96.55339805825244 0.470981590245106 0.6172073949948879 8.039447586992903 12.821385469067062 0.8290554661930905 0.3508533178081804 0.0539466302514174 0.453649864427614 0.5926756913977281 0.2299042560488463 0.0012184003512918 +Reduced visual acuity 42 124 2.7988229160287283 0.0051289257004674 25.553398058252423 114.88106796116504 0.4786956822479749 0.5063280215354549 8.433035081523723 11.838637206126975 1.2158495541746812 0.3830713742278179 0.0578000434384252 0.0257136443113427 0.0512997962814866 0.1345908644659392 0.0464447809917983 +Cherry red spot of the macula 7 10 2.797631635774786 0.0051478785626517 4.87621359223301 9.031553398058252 0.4125318500531191 0.1346012745180574 1.6566187440434876 0.4477283705000042 2.101542046986786 0.2228325403979826 3.630600690936675e-07 0.0015075035399645 0.000188873280149 0.0001472775053537 1.2360646796507886e-08 +Abnormality of fontanelles 12 46 2.7861446707852 0.0053339060539323 12.533980582524272 46.23543689320388 0.679338498231045 0.5021510160434427 4.713779704909753 4.753170281164529 0.9735403185104452 0.3677424081230729 0.0067610849779989 0.0213192735786343 0.0066567518190848 0.0286491714202897 0.0021872891843051 +Progressive neurologic deterioration 7 21 2.7848330328627284 0.0053555292583731 6.75 20.466019417475728 0.5813429756502071 0.2930928839947513 2.6727908035631316 1.300228015706032 1.5791549964390388 0.3142214461904322 0.006650732459586 0.0011928873895092 0.0008016777344491 0.0037658297098364 0.0009526402681126 +Splenomegaly 36 96 2.7790045898222617 0.0054525754661003 20.660194174757283 86.74029126213593 0.5649049994066069 0.3835571498509289 6.419862077062851 7.868335701486235 1.546158503499524 0.3590721878602594 0.0129443407229815 0.0262221556449147 0.0258880871899029 0.0569561152358087 7.160054154345771e-06 +Blindness 31 81 2.7670638194920936 0.0056563680928591 17.50485436893204 77.9878640776699 0.5531690923808372 0.4517712920686044 6.330499123572238 7.312865926515748 1.2869313794328858 0.374312554297374 0.0100275963249388 0.0161114981694795 0.0134142100600963 0.0551918016716766 0.0170542901938563 +Osteopenia 17 78 2.7566162487630246 0.0058402848718446 14.580097087378642 70.14320388349515 0.5468518828167999 0.5898264625753131 5.569149766058337 5.306286565364834 0.7866919750372822 0.3524913522638017 0.0250373846632432 0.0104513239080679 0.0073989810675838 0.0106859275033924 0.0021319149944454 +Abnormal circulating cholesterol concentration 13 34 2.7453809325213347 0.0060440695427701 9.691747572815531 31.70873786407767 0.976903841313624 0.2790879029908041 4.4525142732793395 3.04459115485426 1.5883623188049951 0.3063455707490317 0.0181990227203509 0.0058478787222266 0.0062190088773383 0.0098712464387859 0.0002439853208345 +Aplasia hypoplasia of the skin 14 59 2.734505167921923 0.0062474114674009 10.725728155339803 55.63834951456311 0.4900873083623657 0.601807272560761 4.36891248647189 5.256783430309772 0.7298913802856463 0.3282941109099474 0.0074460005474358 0.0339635306200824 0.0540474468228863 0.0029016065145256 0.0045908848078041 +Increased csf lactate 13 51 2.7240800698151104 0.0064480871747316 14.563106796116504 50.03398058252427 0.4527108683296134 0.4236743568986457 6.839235611227043 5.521257303659666 1.4241114192986506 0.3526497741057939 0.0121270542607023 0.0704839558103872 0.0567924573004668 0.0215360722135964 9.143558711045978e-05 +Clumsiness 9 21 2.70053879695412 0.0069227262348841 6.75 20.57766990291262 0.9027704056640264 0.2559090219975202 2.4698423753801175 2.2221930931993956 1.527926415027724 0.282470536898918 0.0115084565191122 0.2145132052110039 0.3837477700803094 0.0311941867040692 0.000510790199304 +Platyspondyly 11 35 2.7004362641199977 0.0069248603994775 8.28640776699029 33.730582524271846 0.6662607465302498 0.4948187493576657 3.3732974430890796 4.074278380383408 0.9978722835718216 0.3450714604006198 0.0284132294478112 0.000707213496136 0.0088607173186582 0.0521205227118809 0.0006355875237301 +Muscle weakness 60 300 2.7001342515285587 0.0069311500602906 62.08495145631068 284.65776699029124 0.4543336947629458 0.7075817001495509 18.861530859314332 26.81339440066312 0.9176952901579704 0.374241019778978 0.0023654808334784 0.1289689451699084 0.0425931225592926 0.0038871053111864 3.0660232675885894e-06 +Abnormality of the ribs 24 66 2.6902598124834705 0.0071396409525468 15.46359223300971 63.26456310679612 0.6596881680500318 0.4822792711086646 5.162987649103379 7.327989071924885 1.0464354559452582 0.3722680363619953 0.0602924097790232 0.0174923714516836 0.0150034432579735 0.0280298561279102 0.0022076316008824 +Diffuse cerebral atrophy 4 18 2.6896415383632664 0.0071528806983065 4.320388349514563 16.526699029126213 0.5483679808262946 0.4347204443631116 2.152955035100649 2.40585163991881 0.9855175878314706 0.3059596216572743 0.0734030910859718 0.012648542478749 0.0459506122728715 0.0530915597366878 0.0259406914165302 +Recurrent fractures 7 34 2.68757785495968 0.0071972321937461 6.847087378640777 30.946601941747577 0.3213188523109523 0.6042039881506283 3.549704795894447 3.0588187177970756 0.8811845545148387 0.3145604549917675 0.0229247663936103 0.0067553656037119 0.0074628704993106 0.0125771724555126 0.0376283333624949 +Abnormal cornea morphology 41 162 2.685555133512919 0.0072409427256561 30.74271844660194 150.09223300970874 0.1968515799266131 0.7105111239891984 9.65581571261939 17.92341414533844 0.729552037792794 0.3226298921023764 0.0942283069789429 0.4351770237748031 0.7162203449746072 0.4228533661843578 0.0088455718518181 +Abnormally lax or hyperextensible skin 14 43 2.6783412890183467 0.007398778687343 10.3373786407767 42.60679611650485 0.3474462280446399 0.5687204029624341 3.951804420390705 4.299554326326563 0.9473596696641492 0.3538650259671493 0.1412337152639064 0.4637995473310806 0.3511849676405914 0.0880900807686078 0.0428873201837564 +Neuronal loss in central nervous system 5 11 2.6748896489876115 0.0074753851384417 4.087378640776699 12.526699029126211 0.982175765643533 0.2959736314179056 1.731247914675439 1.993135251988059 1.1236470294677874 0.2967990988512021 0.009238076730526 0.0093923264669034 0.0346664630686661 0.0057743966142769 0.0028128505043211 +Disproportionate short stature 14 30 2.656862167529385 0.0078871682492609 8.58252427184466 24.70145631067961 1.4449047806081987 0.2464238748623315 3.3320283680556178 3.793287097673045 1.0910515137563812 0.2952991105687103 0.0121270542607023 0.0093752195011205 0.0112616954341839 0.0059914172581948 0.0037949128027229 +Supranuclear gaze palsy 6 19 2.655310127716776 0.0079235525650231 5.186893203883495 19.1626213592233 0.8242716574954257 0.3183493558985887 2.2612229396433574 2.139608194404574 1.2188387108542005 0.2935859783151378 0.0043547723482352 0.000895633126088 0.006477682080963 0.0024377113202794 0.002448268499096 +Abnormal pulmonary interstitial morphology 5 35 2.6492291034830457 0.0080675620706354 6.371359223300971 30.5995145631068 0.4103689768813533 0.4555813960836699 3.330566746297264 2.186076806332745 1.1224431747517174 0.329794447909787 0.0255709516116318 0.3295231102555642 0.0081420868521756 0.0477957943736139 0.2007835125015833 +Peripheral axonal neuropathy 15 59 2.6447702810644507 0.0081746392541941 13.890776699029129 56.6626213592233 0.647996206639266 0.5297865267121298 5.546380992609976 6.858150910061315 0.9851361073340408 0.3701043540632976 0.1726298175083212 0.1399625708529587 0.1443148752822858 0.1099190288620697 0.0007737853601128 +Bulbar signs 8 13 2.6402276978301376 0.0082850342119467 4.888349514563107 12.016990291262136 1.527818207801298 0.1656113111527082 2.218011046873564 1.4803576942139227 1.2783367300196684 0.2344360472575242 0.0002221586796982 0.0004979568253937 0.0002536939512357 0.0001061688479941 0.0007191550657462 +Bone pain 4 23 2.6136220056812114 0.0089588090902106 4.975728155339806 22.203883495145632 0.6350188771758896 0.4127751797545932 2.519707411717398 2.310210444333206 1.0375367125895096 0.3016728005813124 0.0158315531323641 0.0001255471891058 0.0001621832719882 0.0092216123798009 0.0426924060067812 +Adult onset 26 66 2.612087153826898 0.0089991309535053 15.946601941747574 66.74271844660194 0.3425016355734805 0.6240234703907565 6.375930399024139 6.279247712373597 0.7555871999741639 0.3278262215484402 0.1174603582827228 0.2116527739749005 0.514804159387793 0.0650200504619928 0.084618776213779 +Dyspnea 25 100 2.610833128991045 0.0090321954641066 21.026699029126213 99.08495145631068 0.338494152708191 0.5916975591038598 7.650862365043173 8.679854297666031 0.9096277682010132 0.3494553445560299 0.0065515126655588 0.008762139956178 0.0430709217999022 0.0117273581916356 0.0004028331238226 +Hyperlipidemia 9 30 2.6099471376681307 0.0090556214911352 7.682038834951456 29.6626213592233 0.5392307404617857 0.3728005101645487 3.9693446328110418 2.956030683250849 1.27614168259521 0.3117729697341341 0.1368477428708535 0.0472622034410549 0.0323757559425281 0.2505872457528773 0.1305749524775296 +Pericardial effusion 1 7 2.608169593945607 0.0091027842414574 1.9466019417475728 5.980582524271845 0.6333430474464145 0.2773316461993735 1.2136213588737947 1.4646685732948297 1.3006352977804805 0.2635985168358294 0.1248348676040813 0.1026081339138497 0.0193632099375005 0.099708835751112 0.2906426697670494 +Abnormal pericardium morphology 4 12 2.604650893791957 0.0091967914421322 3.487864077669903 10.762135922330096 1.0304485268572945 0.2849705132346721 1.7172308655515107 1.695717994097398 1.0794817436655069 0.2735310781030822 0.068468596160163 0.1541506060207377 0.0435975481844182 0.0494008625159685 0.0231294135439989 +Young adult onset 7 11 2.6036976325557326 0.0092224079262657 3.936893203883495 11.097087378640778 0.9326277418903632 0.2839315553797075 1.7793033594374144 1.2484130750505644 1.1998221427979727 0.2831359733121 0.0590764560136037 0.1457663642848915 0.27085351108605 0.0424141111811751 0.0039537733222705 +Gait disturbance 63 337 2.6015617437625416 0.0092800358497882 61.817961165048544 311.34223300970876 0.1967292635751156 0.8072644722373569 17.71698673996577 31.583636276568296 0.6180398648308597 0.3074286090643233 0.0033841716327228 0.1117599670565467 0.3032975049010895 0.0209372718739115 0.0001601554759407 +Abnormal sternum morphology 27 122 2.5727659637900016 0.0100889405099244 25.42233009708738 110.19174757281552 0.4566971760702576 0.6169838687654687 7.431648826430472 11.361219588504673 0.8416956950389548 0.3481564624731069 0.0638410803146677 0.2053566616012395 0.2035603839475402 0.1579343465373446 0.0017819623521439 +Abnormality of upper limb joint 24 119 2.570504670250898 0.0101550457509078 22.174757281553397 112.72815533980582 0.5181453657197084 0.6203796408917344 7.717622231118391 13.742566693149987 0.824816154844266 0.3600833350084496 0.1896568838532417 0.0072544741584431 0.0224262424579216 0.1554432394760176 0.0378864207986457 +Abnormality of the parathyroid gland 4 21 2.561463468177441 0.0104232202709129 4.699029126213592 20.546116504854368 0.6237618755864083 0.5009535063764416 2.3712884190123216 2.9764952130680324 0.9346790271256726 0.3344585569453652 0.0211214409177817 0.0026953565990113 0.0023109570743477 0.0501037692041591 0.1427791401704325 +Delusions 10 21 2.531484479178558 0.0113580844072367 5.912621359223301 18.439320388349515 1.0629964764413025 0.2985925736346436 2.390745896997379 2.2281751696560335 1.2165016471530676 0.297036724651636 0.0158339836124163 0.0006503204391585 0.0047719907059414 0.0530915597366878 0.0012662122150735 +Fatigue 17 82 2.520954601287548 0.0117036950863247 16.91504854368932 80.75 0.4479867994971399 0.6200877637843074 6.007282534078571 7.6753371893926445 0.7480205814873203 0.3310366012861978 0.0323432465318045 0.1078159107849693 0.4065486567308921 0.0624725539047053 0.0205613890838106 +Peripheral axonal degeneration 18 75 2.50876380365482 0.0121154465268213 16.691747572815533 71.19902912621359 0.6211832637355972 0.5650732986012978 6.425044282599762 8.4263916789636 0.8780908495791551 0.3675751486040735 0.0890314708588128 0.1919587855748741 0.0774564415615361 0.0478113538577985 0.0003791758575639 +Arteriosclerosis 7 15 2.5070093185657583 0.0121757501700556 4.885922330097087 14.944174757281552 0.0721468675738393 0.2032976413320727 1.852339343238996 2.0572604199467093 1.788928597657784 0.2405012300780825 0.0105692359732665 0.0230307909850112 0.0803264485176453 0.0291888164392555 0.0080473050001108 +Abnormal csf protein level 7 13 2.5043678766272945 0.0122670412190846 4.434466019417476 12.20631067961165 1.1239853500963992 0.2260559983233297 2.11400242863219 2.084072511592451 1.241935948510828 0.248039542652958 0.0228129097057376 0.0155575631698287 0.006477682080963 0.0146129998399771 0.0106880220145335 +Dermal atrophy 5 29 2.498429436859613 0.0124744974670671 5.320388349514563 26.895631067961165 0.7910895542770026 0.4477466139002859 2.6272049167180267 2.645986214694848 0.8422228280317593 0.3177571120785681 0.0531204099012568 0.0496758524768897 0.0347449548593629 0.0326937613140359 0.143549387276975 +Dysostosis multiplex 5 10 2.494903906917552 0.0125991244531353 3.983009708737864 7.990291262135922 0.4150973501220912 0.1595724105588133 1.65382835361071 1.246316090990369 1.8479195153421644 0.2123242141003258 0.0002320130883185 0.0981765691424607 0.0177148463510605 0.0014975917181939 0.0003730251283681 +Gait ataxia 15 71 2.492934376629659 0.0126692259052618 14.351941747572816 68.35194174757281 0.6787136514518399 0.4783255809544575 5.256980668043156 6.678826209042067 1.046898326537344 0.3693668840587258 0.0065699086738207 0.5585728030790713 0.2200423778280186 0.0072038425142067 0.0065157582264611 +Abnormality of bone mineral density 32 145 2.485268680054937 0.0129453688987337 27.356796116504853 134.4368932038835 0.3643048003328085 0.6271112047303443 9.127541669014532 13.17298640894851 0.8979996901173003 0.3610272080787325 0.0202522548022249 0.0102473831162043 0.0121212214757854 0.0239977652861024 0.0008625066054372 +Osteoarthritis 5 9 2.479747061171508 0.0131475611359743 3.783980582524272 10.466019417475728 1.011181157871384 0.2141266987491498 1.7388858389175554 1.4384831140913243 1.3548711699904423 0.2434324139099127 0.0422971632022364 0.0082126449787597 0.002509898486982 0.0300655360870906 0.0103633783340074 +Abnormal arterial physiology 9 30 2.4704353348078394 0.0134948714760039 6.218446601941747 26.953883495145632 0.6799967252485163 0.4871419269266132 2.869465887610158 2.4604264895945303 0.8630108658008876 0.3264277839815205 0.0418328415954365 0.3619523256513019 0.5938019181425528 0.0716306528529756 0.0127124954693858 +Abnormality of the tongue 21 99 2.468719900323248 0.0135597310244739 22.424757281553397 89.52912621359224 0.5421010507218363 0.5607339999720974 6.938472222740965 9.436122816051313 0.9593463898963266 0.3606735981467843 0.4885983805501653 0.3852166760795645 0.4989837714349443 0.6538046055279653 0.0127879151493013 +Scotoma 5 10 2.4685437545367463 0.0135664065577243 4.189320388349515 12.196601941747574 1.1271039056750725 0.2779036999445621 2.1128553643245884 2.0698220238662226 1.1901076059375446 0.2884356618441315 0.0248070742612381 0.1788224008957527 0.0583817580096799 0.0159331781494728 0.0120719478590556 +Elbow flexion contracture 9 29 2.468005680175638 0.0135868163630155 6.728155339805825 25.49757281553398 0.4005296068252059 0.5766090162654979 3.258876376606738 2.9283505301145505 0.8105730741101873 0.3220832838154132 0.1173271790176747 0.2813938178053637 0.4844502219581325 0.0808304233724746 0.0013809720441502 +Increased serum pyruvate 11 35 2.4593619376390228 0.0139184219947554 9.303398058252426 32.64563106796116 0.7845790996019184 0.387018609503293 3.945341127018032 3.24570744750092 1.0586848930233297 0.3138975633269482 0.0002985908004192 0.0221396463904123 0.0011244794942918 0.0055460197819823 1.6895788053657228e-06 +Ventricular hypertrophy 11 40 2.4562790243319133 0.0140384110092939 10.04126213592233 36.45873786407767 1.1361758135608295 0.3518404639351837 4.440080726024568 4.153106961798495 1.0569836433105884 0.3376234863759063 0.0498217239267589 0.0111951113174208 0.0140469368115112 0.082698802989994 0.0411573249463058 +Retrognathia 19 82 2.446302978131751 0.014432965694429 14.941747572815531 78.44660194174757 0.2365191550642606 0.7173627889305809 6.857531105895135 8.90699316762686 0.6545883538913462 0.3002876583610596 0.0955492633134715 0.004553922175855 0.0222374236047442 0.0469100654983868 0.0772492290183042 +Horizontal nystagmus 6 25 2.437309402079112 0.0147970125072425 6.274271844660194 23.053398058252423 1.1086320165192889 0.2915732095622053 2.6115907074401723 2.1860242554539786 1.3408731048130669 0.3129960018850027 0.0636388778287945 0.0023085518548632 0.0158208073938894 0.0424139427802885 0.0150905845261323 +Fasciculations 9 36 2.433027941813053 0.0149731453672194 9.201456310679612 36.5 0.4731561459207285 0.4826265043963199 3.4648999783170837 3.557775567723639 1.0532476984865673 0.3454376907067654 0.0032978239808511 0.2919842266274133 0.1502138999638582 0.0279194128393474 0.001939589155648 +Urinary glycosaminoglycan excretion 3 7 2.425591270392804 0.0152834721868213 2.9490291262135924 6.563106796116505 0.4749855796693131 0.2196485727407601 1.2846457065606351 0.9261036754709504 1.6390629541794843 0.2603486997442626 0.0006394246968973 0.0711332726649859 0.009201700056446 0.0052676758380378 0.0049176108076387 +Parkinsonism 9 29 2.4240909713360383 0.0153467605586383 7.453883495145631 30.097087378640776 0.7249761134976155 0.4663275088289313 3.116711838694066 3.708464636913605 0.8967824567735009 0.3291722600978801 0.0101452461427695 0.0085356676981486 0.0522493976540893 0.0049682424819734 0.0086796345032239 +Central scotoma 4 7 2.4119457419684966 0.0158676426877426 3.657766990291262 9.152912621359222 1.2790732929494344 0.2261272578521709 2.0233738200365714 2.077016218281829 1.2675536526802949 0.279373459017325 0.0385377758267946 0.1244478155008913 0.0285062952815799 0.0273244092926374 0.0088588626715525 +Abnormality of the upper respiratory tract 22 107 2.404408826883987 0.0161986463128753 19.66504854368932 95.80582524271844 0.4534569687157453 0.5959175600884278 6.924659870205313 10.36312380503997 0.9632839800839448 0.3651113920771414 0.0089470735820582 0.4284458426436702 0.5588421793121536 0.0296600289329144 0.017853813532958 +Optic atrophy 54 198 2.3898923504521443 0.0168533118255176 39.97330097087379 184.7135922330097 0.2254846155090266 0.7235761385556879 12.871537267469767 19.604722774296683 0.8047704019364031 0.3342405671672314 0.0748054647035107 0.0824991950890139 0.3243320271559112 0.2742937841149354 0.0249627531639313 +Respiratory distress 22 54 2.3897022905159706 0.0168620349938597 12.805825242718448 52.09466019417476 0.6386570898760532 0.4437575130669694 5.288397728288474 5.051988998968333 1.24726945526474 0.3693239953771813 0.0127815819864285 0.0041154920344419 0.0101228198212069 0.0168565811109024 2.4502578651498425e-05 +Abnormal mitochondria in muscle tissue 7 22 2.3847961442091505 0.017088587785526 6.864077669902913 20.83252427184466 0.7962580997895766 0.3538054675594747 3.0570578650205316 2.639985737842691 1.2479322885734705 0.312408674687376 0.0030521800044401 0.0133509861907553 0.0051691469811439 0.0110758722051871 0.0002681869997004 +Abnormality of glycolipid metabolism 5 8 2.3825129373533893 0.017194927777097 3.83495145631068 7.228155339805825 0.3163887308740252 0.1681411938672545 1.311614193945771 0.5964160722258837 1.870431483654663 0.2292796295173983 0.0001098914636039 0.0479914252810258 0.004071454093033 0.0234889728544392 5.489393781591606e-05 +Myalgia 11 41 2.3819343969414466 0.0172219652100911 9.351941747572816 41.512135922330096 0.2129059813805233 0.6672620498292179 4.031420419473563 4.207869223134299 0.7173151579161029 0.2973604523602463 0.0112405353212617 0.4164957533300368 0.2898593955770666 0.0505154786338523 0.0065784016161601 +Ectopic calcification 14 57 2.376917445710903 0.0174579948481854 13.553398058252426 56.53155339805825 0.5275931647443897 0.4410566614950294 4.995100814049753 5.994858194438004 1.2985638579898735 0.3743313818119885 0.0229796126198492 0.0058502019358225 0.0150628386019023 0.0285922335763531 0.0055524390008335 +Joint contracture of the hand 7 47 2.368772666625635 0.0178472196267236 9.33495145631068 47.52427184466019 0.6899528308551226 0.5319748768374064 4.138903957392258 6.987637711020041 0.8046601985034184 0.3400891059680895 0.1230991638759514 0.0108639142832434 0.0078063040086141 0.0685141250719953 0.4947931249748131 +Abnormal lower limb bone morphology 40 180 2.366638268890368 0.0179504677159407 36.657766990291265 165.25728155339806 0.5352167715889311 0.634339097616788 11.388414435872194 20.95665476687095 0.8935720216867307 0.3771208726436903 0.0842500778213366 0.0046573671613962 0.0861810498662998 0.2580031979473621 0.0034441926578923 +Submucous cleft of soft and hard palate 6 24 2.360769399762519 0.0182370668699951 5.138349514563107 22.941747572815533 0.8980380147163236 0.4007892874523231 2.272201189765468 2.581958475140233 0.7850752745431548 0.2945527466716488 0.0080929753489373 0.0035835009476038 0.0237837250606552 0.0185767987624415 0.0325410063420203 +Sensory neuropathy 9 34 2.344576427595081 0.0190487060525976 9.17233009708738 33.75485436893204 0.684837850359792 0.4572087500958895 3.983815730493952 4.346698415431409 1.0448123352909229 0.3439679266340525 0.3498219734017346 0.3092959809067388 0.1674383799538608 0.2770823582814727 0.0032642482875436 +Abnormality of hepatobiliary system physiology 25 82 2.3425570625657675 0.0191521050499636 18.737864077669904 78.23543689320388 0.6753867917166245 0.4584905924436965 8.191827759406172 8.347745847320367 1.279744288983872 0.374212423907768 0.0650883850254834 0.0065722437922867 0.0171603994289533 0.0809926544896275 4.486964230171394e-06 +Hallucinations 12 48 2.340649752818157 0.0192502165989669 11.20388349514563 45.44660194174757 0.6705549628539956 0.4221278622600144 3.902598644570227 4.462852401771342 1.2595119979903464 0.3693437289960082 0.0018892602820579 0.0014196759684226 0.0029612996216462 0.0030409582401221 0.0010723609662722 +Osteolysis 4 30 2.3394731709043226 0.0193109585095148 5.286407766990291 27.73543689320388 0.5057473150905948 0.5186942536500823 2.7835351045722914 3.2828484188526224 0.8911453392732208 0.3083503296551068 0.0274480195124167 0.0002173851703999 0.000316040607354 0.0163483070474244 0.0750518175373725 +Airway obstruction 5 17 2.3304395502755217 0.0197829314733677 4.116504854368932 15.12378640776699 0.9459797966632624 0.3434111484412289 1.9597947726604712 2.1010208413382245 1.0021021721123982 0.3085532788047633 0.0226034843701541 0.2486824788491954 0.1106573079891401 0.1682806103596247 0.0616372597750657 +Respiratory failure 18 64 2.323791706389645 0.0201366604642916 15.308252427184469 64.92233009708738 0.6334303745407566 0.5052857133990365 5.520010364276267 5.289556151454055 0.9962199001839442 0.3695677120431103 0.0331612201140871 0.0073513437967763 0.0695854338921134 0.0398239230228283 0.0442225424360613 +Limited elbow movement 10 39 2.3236020864780325 0.020146830509182 8.830097087378642 35.36407766990291 0.3473075768463138 0.61493055701004 4.099522466897024 4.319010907287496 0.788513801550926 0.3172232758685046 0.3124096883657341 0.3928429005031874 0.6322723581240091 0.2332800595093329 0.0098156715029369 +Abnormal social behavior 15 72 2.3232152484012505 0.0201675920225943 16.796116504854368 65.80339805825243 0.6678301735588785 0.4940185804874849 5.994105880514205 6.839540104535511 1.1033956384068455 0.3774724921329495 0.0167378547991893 0.1919587855748741 0.217474521589611 0.0478113538577985 0.0025804138601819 +Abnormal aortic valve morphology 13 43 2.319457644038086 0.0203702351982191 8.643203883495145 40.00970873786408 0.3771375227817258 0.6013013640738508 3.3791734249815333 4.169922691726094 0.7682658177529654 0.3210565311311592 0.0719846879017711 0.1332928413805449 0.3653872604900754 0.3925500418107061 0.0042442718335591 +Abnormality of epiphysis morphology 22 63 2.318772170382532 0.0204073929281831 14.885922330097088 57.24757281553398 0.6699051414631522 0.4959188251133739 5.664066249559964 8.729587504130462 1.029966158611096 0.3689041276003297 0.28635647632432 0.2406407895411775 0.5622114389107989 0.324055581019685 0.0054462243564143 +Abnormal rib cage morphology 19 79 2.3172678254091146 0.0204891468313037 17.694174757281555 75.7135922330097 0.5488633555797945 0.5379800174608891 5.594611229067785 9.71314341791714 0.9782995531616954 0.3690468558866111 0.0979660465550656 0.0349846041813154 0.0379296268847538 0.0914919943439657 0.0117295630935778 +Abnormal cartilage morphology 3 13 2.3140909688117306 0.0206627327077797 3.1990291262135924 12.25242718446602 0.2463325696611419 0.4916908795514706 1.9381702483974472 1.2343658928045838 1.0349646859752573 0.2956464310458583 0.0081826700022156 0.0087935329278829 0.0325598174288622 0.0051006501172469 0.0501437556032915 +Increased cerebral lipofuscin 4 5 2.306044939357846 0.0211081214066237 3.0970873786407767 5.118932038834951 1.0434065701738664 0.1270836154757583 1.1278862704044743 0.4599818751628888 1.7720117842909846 0.2267161680252343 0.0001098914636039 0.0010343090391069 0.004071454093033 6.494328716879693e-05 5.489393781591606e-05 +Generalized myoclonic seizure 8 45 2.3001393957918936 0.0214403239695102 9.177184466019416 40.04854368932039 0.4529392195590967 0.4207459458757411 3.6022058822892773 4.354728800706526 1.2466313924241157 0.3493918392140687 0.0528886029690114 0.0028525731907948 0.0066567518190848 0.0757785059975643 0.1346787832412323 +Poor eye contact 10 42 2.2910029026315497 0.0219632457834151 9.774271844660197 38.25970873786408 0.6634270903175611 0.4886810186458507 3.917228340019005 4.329065002822378 1.0573021214973186 0.3538640004920722 0.001028506132963 0.3058671484100957 0.163965403057363 0.0092655639805929 0.0008357361148287 +Increased bone mineral density 8 27 2.286283513830023 0.0222376777243553 6.242718446601942 24.75 1.1480702818250033 0.3148175930983396 2.4533156459354677 2.2345749579547443 1.0849696139569316 0.312718333498069 0.0052208071738708 0.0533785743764077 0.006515948460693 0.0024819922622898 0.0111310072807516 +Ventricular preexcitation 4 6 2.2802670296579937 0.022591855990111 2.5145631067961167 6.497572815533981 0.9841118497305948 0.2225227126053997 1.468861772329754 1.5757549992030588 1.3097679632537274 0.2453287763295943 0.0150287441417472 0.0892490045576324 0.0146091852998709 0.0104402688493973 0.0017585862412997 +Hepatomegaly 48 179 2.2790088473130554 0.0226665393817984 39.728155339805824 169.55582524271844 0.4089837357771489 0.5280564448988146 14.21621812446184 16.25283515367601 1.2317505616434137 0.3902252758923212 0.0012029716926105 0.0110171777183305 0.0013653675900257 0.0136619685228929 1.0156657614966937e-07 +Ascites 9 29 2.265087296779666 0.0235073230152638 6.538834951456311 25.800970873786408 0.2860997134153194 0.2561597752608451 2.6559964399945706 3.331112387328855 1.6846905274497244 0.2824645045304154 0.0035731750825312 0.295480255529908 0.1536294983436044 0.0952213329894842 0.0214122280347988 +Emg neuropathic changes 10 23 2.263878408044667 0.0235815943015103 6.915048543689321 24.58252427184466 0.5887299592537784 0.4208819793990807 3.046574831105746 2.544837804909062 1.1306803597402475 0.3318248802653038 0.0363235987460939 0.1988423464133734 0.3588505448912167 0.0966974979109908 0.0002619380543045 +Thin skin 7 28 2.261751880052006 0.0237127374042072 5.233009708737864 24.262135922330096 0.5619176829908993 0.56634777500469 2.7153067859181794 2.501305154648419 0.6915958695001003 0.3147007677784247 0.0069263127817143 0.0358926009784828 0.1202677732034906 0.0036079185825643 0.009016982971419 +Inability to walk 19 94 2.2583996891743703 0.0239207520935489 16.66504854368932 84.69902912621359 0.4056115860733718 0.6149200897254583 7.231232270040466 7.352874018977716 0.8216232864046632 0.3415658846811537 0.0232044083801421 0.6257786575609776 0.8606434481059522 0.0537872477106423 0.0015441731623467 +Ascending tubular aorta aneurysm 3 5 2.2583883563408627 0.0239214580095685 1.3907766990291262 4.655339805825243 0.9226580213396618 0.308376966533443 1.1148653010373335 0.8882434018008132 0.9888017972034884 0.2648823222498504 0.0567913213537204 0.066549445548378 0.1289666473793992 0.0445602183527292 0.0037486095651754 +Poor head control 16 74 2.253326245212072 0.024238586120209 16.62864077669903 70.83495145631068 0.6551149189569596 0.4893764407721695 6.123760433086226 7.081833846449059 1.1601225008146194 0.3772060433763 0.0078022809992076 0.1603872358408925 0.014274462104135 0.0266429718875588 0.0007163263345613 +Hydrocephalus 25 89 2.252535839807127 0.0242884304924886 17.5 74.83009708737865 0.4864280032519437 0.6085787069163106 5.8879092832817435 9.478912056611868 0.8088784016382273 0.3500416531762792 0.3905136026643216 0.1598900155921283 0.5258268726912071 0.6911596911049114 0.1446997954223826 +Abnormality of lower limb joint 36 178 2.252180248775934 0.0243108836571848 33.80582524271845 166.25242718446603 0.2412979108610408 0.7714482514929651 11.09824463722585 17.08912584844864 0.6310491383229854 0.3006235946777967 0.0172119156002069 0.0877495061681196 0.3401056445205598 0.0505450092300472 0.0042649465356824 +Pulmonary fibrosis 3 21 2.247784214946715 0.0245899528928568 3.934466019417475 19.601941747572816 0.249651568228048 0.5789497476216486 2.416182589767948 1.353455167270249 0.790614601405684 0.2834869501430559 0.0416615583603299 0.2067156970649581 0.0108633849740392 0.0272622697998741 0.193832289989472 +Foam cells 5 7 2.242023267835562 0.0249598685398861 2.9611650485436893 5.398058252427185 -0.064606162326146 0.1366553329191208 1.1817572081322671 0.893230265545378 1.9405286208577948 0.1862104272675829 0.0010903561613953 0.0385773062479974 0.0758460972151271 0.0150927838189798 1.3236156489067347e-05 +Proportionate short stature 9 35 2.2400781293413536 0.0250858511173646 8.20873786407767 34.116504854368934 0.7111768198576495 0.4559300049156646 3.388318218343798 3.7920483254309434 0.966379822462628 0.3393663702605685 0.0790776759763437 0.0154102901166228 0.0877302870164678 0.0468934279705003 0.0351413027881584 +Abnormality of the curvature of the vertebral column 64 343 2.236643892677173 0.025309623764274 61.24271844660194 311.63592233009706 0.0979422930498871 0.8557307939623847 16.307551422170867 32.37760329337386 0.4962387488825894 0.2615300993012245 0.0576722145667277 0.0562342312017763 0.2208254499357218 0.1497295701048043 0.0003525593447354 +Myoclonus 24 105 2.2315502060656893 0.0256447057654931 19.92718446601942 92.40291262135922 0.7794869182612147 0.4142145469430702 6.660238401732631 11.33633180094438 1.369340457412049 0.3858779422292388 0.0127617875930829 0.0080948593790297 0.0036009286451109 0.0232125183769075 0.0033216565258275 +Abnormality of the gingiva 9 47 2.2221113341695813 0.0262757824937487 9.87621359223301 46.04126213592233 0.4066177797442131 0.5493526186039737 4.388501882181702 4.364546747363985 0.9993836878157942 0.3390641087927739 0.2335532788267403 0.0357664341382327 0.0574462537203819 0.2947939516886352 0.1839878838934932 +Abnormal atrioventricular valve morphology 9 38 2.217527518681028 0.0265870647102599 8.29611650485437 34.550970873786405 0.3559605466693524 0.638830103597311 3.185172636497227 4.1884983556019 0.6951083755057744 0.30928862834681 0.0491319229157538 0.1153703567090803 0.1115354306593847 0.0711465500702303 0.0641124042911101 +Hepatic failure 15 51 2.204312449813824 0.0275023779904883 12.25242718446602 48.050970873786405 0.7424989852941342 0.3814651163177168 5.527018274076851 5.448329576476532 1.3577793424610205 0.3539023729255708 0.0659189780127148 0.0135596849536518 0.017807274362228 0.1041061613928924 3.0294859511611988e-05 +Avascular necrosis 5 23 2.203142924643731 0.0275846765920269 5.070388349514563 21.203883495145632 0.6420454351604097 0.3947374085674277 2.2614105153836106 2.2592172512550373 1.1319127818663337 0.3183649666305153 0.0211214409177817 0.0026953565990113 0.0023109570743477 0.0124412460735711 0.0575078377952935 +Abnormal femoral neck head morphology 13 49 2.2012681811704717 0.0277170440301035 11.097087378640778 44.88834951456311 0.710356821644891 0.4647128189516342 4.081724752298962 5.521112188696193 0.9531654138623804 0.3489729073692786 0.0652184175025753 0.0241824215416069 0.0360480226729306 0.0359262675125223 0.0034326595266602 +Wide cranial sutures 2 7 2.199998083263464 0.0278070310181803 2.0145631067961167 7.703883495145631 0.7152221419680245 0.3932675421341624 1.400340303092121 0.8783725385755785 0.8965275088954128 0.2767752142477642 0.0092378701630156 0.0756950383436983 0.0104494791604543 0.0569248849368824 0.039942155971048 +Progressive psychomotor deterioration 5 9 2.199005981279044 0.0278774970037105 3.349514563106796 8.320388349514563 0.5379615244672443 0.2176134167318772 1.5053866894387542 0.6226094824456632 1.5848775742530583 0.2457660654605461 0.0427179386115036 0.0015075035399645 0.0058956460302812 0.0333651833289618 0.0020033682110678 +Skeletal muscle hypertrophy 9 47 2.197995003451852 0.027949462003757 9.978155339805824 43.95873786407767 0.2882267398053342 0.5822719825831179 4.164926192558732 4.192080647433412 0.9226697759716594 0.3424177343120818 0.5066513655944881 0.4795806297081992 0.7300418430072014 0.4036317239711513 0.1091815923445466 +Posteriorly rotated ears 21 112 2.1976444669906643 0.0279744518002176 22.179611650485437 108.6504854368932 0.4817735830108808 0.6409255719604446 7.3320530406518625 12.346894376126524 0.7519045403366967 0.3519188615999026 0.1525237390466101 0.0243208698529704 0.0480823749469222 0.1247799251573586 0.1001661145850124 +Optic neuropathy 7 22 2.197508223420616 0.0279841698211886 6.834951456310679 22.009708737864077 0.7947386425872367 0.3403162177193031 3.144874354625535 3.3508299091739815 1.3090216253320466 0.3062511530983536 0.0105692359732665 0.2106238865633207 0.0803264485176453 0.0291888164392555 0.002003382390012 +Progressive sensorineural hearing impairment 3 10 2.192312219181514 0.0283569700497028 3.1092233009708736 10.177184466019416 0.6816533912969537 0.4125027093829873 1.9409267075593708 1.400472817159746 0.9707665840558262 0.3067183945172701 0.1636169873806569 0.1201219647894398 0.0265618978442646 0.1318172807011351 0.0353483729682259 +Abnormal cardiac ventricular function 4 19 2.189041278228616 0.0285938399408702 5.262135922330097 18.648058252427184 0.6561483334031016 0.4063512942618581 2.801563935800768 3.037775296806565 1.0608023601658336 0.302693194134391 0.1629349379726378 0.0533785743764077 0.0384628064123942 0.114772391772967 0.3104475196004186 +Abnormal systemic arterial morphology 40 152 2.1852480317909 0.0288706654996353 26.512135922330096 139.09223300970874 -0.0457047476890588 0.6345296488429398 8.296820557307836 14.036057514403687 1.004196439476248 0.3481529181225943 0.002718372656776 0.1199184951243544 0.1779424708630057 0.0136619685228929 0.0002712572415806 +Bowing of the legs 11 54 2.1761902871619365 0.0295410348903997 11.155339805825244 51.15533980582524 0.3696320760225168 0.6089630438985444 4.432902753984072 6.8301264136382995 0.7679030342482581 0.32405716235975 0.0248083535749441 0.0369955408328181 0.05977481033742 0.0306380548251407 0.0616379031275874 +Bilateral sensorineural hearing impairment 8 27 2.1750743636426746 0.029624544227141 6.381067961165049 24.424757281553397 0.7447297270654177 0.4543730451773109 2.694462286764978 2.8252792093863337 0.8997615483176746 0.3241521581359238 0.0636388778287945 0.0286799036387023 0.0158208073938894 0.0424139427802885 0.0150905845261323 +Calcinosis 1 5 2.171651149576093 0.0298819858028198 1.5072815533980584 5.099514563106796 1.1513451038285936 0.2590169313384529 1.041584579038491 0.4030222683885372 0.953608514142629 0.2639318719258676 0.0302121860941904 0.0479914252810258 0.0938999510605359 0.0234889728544392 0.0820486275159116 +Abnormal retinal morphology 54 231 2.171345672394247 0.0299050522964419 45.478155339805824 213.00485436893203 0.2870296460039429 0.6766928177985854 13.550409605643804 22.682270903247453 0.9517483504445162 0.3613196633465952 0.0281133441055056 0.1004832697322205 0.1946301786792487 0.0512951520264608 0.0277608728652017 +Respiratory arrest 3 9 2.167856191102282 0.0301696299524978 2.0558252427184467 7.070388349514563 1.3186130117670736 0.2232983865916446 1.389730031946098 1.4320861436977392 0.8270726521635177 0.2287950263954721 0.0888209252237206 0.0847528009868792 0.1626892876910785 0.0703212183088513 0.0098193480789534 +Progressive external ophthalmoplegia 3 9 2.164754804648541 0.0304064676073845 3.378640776699029 10.228155339805824 0.6986896615619974 0.3934319655103426 1.8174798771838792 2.269764004486748 0.9524665755192452 0.2940766219203315 0.0385377758267946 0.1244478155008913 0.0285062952815799 0.0273244092926374 0.0399552443236748 +Abnormal csf metabolite level 13 59 2.162691959465848 0.0305648799391842 15.62864077669903 56.38834951456311 0.3728365451013375 0.4594620050205593 7.183479908053284 5.909073177714687 1.318852118504194 0.3560984107552507 0.030177172704391 0.0966324665930835 0.0877302870164678 0.0468934279705003 0.0006537202959547 +Abnormality of visual evoked potentials 8 22 2.161534061901777 0.0306541087262097 5.912621359223301 21.344660194174757 0.5310511795384435 0.4083718861321034 3.290488782756552 2.4160960308239137 1.1796429833196167 0.3304773196682204 0.3392300900759293 0.1908924307699622 0.3460310778663031 0.2829018108703478 0.0169717228577044 +Abnormality of the larynx 11 52 2.1597793820603157 0.0307897524914022 10.682038834951456 46.699029126213595 0.7426785971038559 0.4816723930500222 4.067795342682343 4.403407664230521 0.9382180075001202 0.3633154044529258 0.0229796126198492 0.5194717620066895 0.7699332370232862 0.0705579259459618 0.0567909348296337 +Micromelia 5 24 2.1486165347562927 0.0316648098748733 5.094660194174757 22.143203883495147 0.8629445430209934 0.441515711810184 2.300964472974588 2.4557002100293746 0.9703688762337884 0.333324080713348 0.0141884573079573 0.0050180872027471 0.0051214743942411 0.0076080813078773 0.0564249445308771 +Cough 6 28 2.1482555483009365 0.0316934600739742 5.548543689320389 25.45873786407767 0.1408926542867418 0.6345115539557413 2.9345734238778345 2.623779671816255 0.7136376301986084 0.2766617941880244 0.3651703268663231 0.3161039234082394 0.5331665625078387 0.5647328054199106 0.0800183414605077 +Postural tremor 8 18 2.1413973331995284 0.0322420098199818 5.194174757281553 17.851941747572816 1.214872214945056 0.2487017685351703 2.341305968762478 2.2981463861426747 1.2391489410765593 0.2821199379659175 0.0007801778634092 1.0 0.0583817580096799 0.0003819251815083 0.0001003888941435 +Abnormality of acid base homeostasis 43 182 2.13999979645011 0.0323547831942421 44.50485436893204 170.373786407767 -0.2233908942344595 0.5721951722190072 19.847904091451365 14.676977951186718 1.2815984847829789 0.3621197031342936 5.912094665079269e-05 0.0007431009346098 0.0033996283133253 0.0016122756159424 4.524746672307764e-09 +Mania 4 14 2.1370157089518576 0.0325967139500811 4.29126213592233 13.815533980582524 0.5633198814967983 0.4160552944360035 2.179476502394243 2.2801276272213657 1.0919629859527038 0.3085705503430486 0.0015413212391776 0.141543756104335 0.0368247433715485 0.0391216296567294 0.0159032502878613 +Muscle stiffness 4 19 2.1359320010935896 0.0326849567581408 5.109223300970874 19.216019417475728 1.2530133657268057 0.2695837776665858 2.5817154639007844 2.4582801786037667 1.0397164239726309 0.2961148999712332 0.0671908726884138 0.0024333620388206 0.0166167011229059 0.1505670934775949 0.1280001064666262 +Hypokinesia 6 13 2.1221771398665505 0.0338228654769381 3.3228155339805827 12.177184466019416 0.7049731134993743 0.4050382900786843 1.785911378374969 2.0633566382130173 0.9326231482443949 0.2932516715732374 0.0072095476995203 0.0082126449787597 0.0305060181117638 0.0044816860022438 0.0002995500484788 +Ankylosis 2 5 2.118192974307986 0.0341587279583328 1.7160194174757282 5.099514563106796 0.776290643053947 0.3289690792318075 1.1013829257517682 0.4264322039260138 1.078831323421012 0.282224813150681 0.0567913213537204 0.066549445548378 0.1289666473793992 0.0445602183527292 0.0278921605814954 +Abnormal bleeding 23 111 2.1161730822540035 0.034330089671152 21.04368932038835 103.1480582524272 0.3205179723276434 0.6638707666517285 7.482862879563674 10.194702656234456 0.7473134672907507 0.3396929867916743 0.0086954324850462 0.2079001035716013 0.2070365152621195 0.0054151541748786 0.0073854732999671 +Abnormal metabolic brain imaging by mrs 5 18 2.115730723973038 0.0343677159454811 4.606796116504855 16.54854368932039 0.7235353195513555 0.4019359214719802 2.5477483733613684 2.1144608015049493 1.0143737900681629 0.2966800307492503 0.014331659651373 0.0119629297909749 0.004393919895815 0.0494008625159685 0.0054053690368969 +Abnormal morphology of the musculature of the neck 5 14 2.111088735238648 0.0347646854953034 2.6237864077669903 13.473300970873789 0.6063883248814701 0.4967060238844604 1.853026187474353 1.6726717703016651 0.7926132510244637 0.3017521656103346 0.1003001736992858 0.1788224008957527 0.3263246311566628 0.2555664496894125 0.0120719478590556 +Abnormality of the spleen 43 137 2.110846012358948 0.0347855497503317 25.813106796116504 118.70145631067962 0.3588217969137363 0.458825127767632 7.787937091054707 11.816587724549532 1.4144879662363967 0.3705037351683085 0.1114168088517736 0.0910053419471295 0.1278164313017142 0.2341965636557551 0.0001875125920481 +Pathologic fracture 8 18 2.108534747428187 0.0349847604204658 4.257281553398058 15.072815533980584 0.983166532607372 0.3143076297274698 2.133145812327421 2.2800397788540345 1.0713003315034937 0.2893419439464214 0.094638191244273 0.1747599807978781 0.0558103535730672 0.0691213376044611 8.125377290359248e-05 +Pedal edema 1 7 2.1065531997561178 0.0351563270807944 2.092233009708738 7.211165048543689 0.6115824815809859 0.289867756561444 1.3297338459429695 1.219410808682535 1.3115580791228945 0.2762999280116011 0.1636169873806569 0.1201219647894398 0.0265618978442646 0.1318172807011351 0.3630866560691931 +Hyperconvex nail 5 9 2.1046883436764854 0.0353184457977822 2.405339805825242 7.939320388349515 0.7351828941114927 0.3065172604341125 1.3467943353086171 0.7527989998960608 1.0793151443208264 0.2411455315204656 0.0427179386115036 0.0573151884822011 0.0058956460302812 0.0333651833289618 0.0001590313802548 +Vitiligo 1 8 2.103982805798019 0.0353799468985307 1.75 6.893203883495145 0.5228034908965178 0.4514214081097454 1.549545815072826 0.7902638291080828 0.9503325655279016 0.3007892778972581 0.1248348676040813 0.1026081339138497 0.0193632099375005 0.099708835751112 0.2906426697670494 +Action tremor 14 59 2.102844944994028 0.0354793257329257 13.143203883495143 54.47572815533981 1.1235280535029035 0.3645421720231636 5.4627047451961745 5.814853194507433 1.1817578847970691 0.3688885139588422 0.0036590733759291 0.1349531687426338 0.0092324336297151 0.0013655868178279 0.001713786813282 +Short palpebral fissure 8 33 2.101337927457036 0.0356113126234345 6.29126213592233 27.92233009708738 0.3913672129346548 0.6272266742698988 3.03660857057613 3.451295860157005 0.6967404872312752 0.3059936066215196 0.0824529623114899 0.0623838765899965 0.195637464602177 0.1448052296118594 0.108533579096118 +Stillbirth 3 12 2.0966370705206643 0.0360257150807366 3.145631067961165 11.177184466019416 0.7032160695176418 0.4106957336237037 1.7385283755040757 0.8562527499503464 0.8448273274133665 0.2731066189783109 0.0024564584457719 0.0046633751497463 0.0177148463510605 0.0014975917181939 0.0171177319456962 +Abnormal epiphyseal ossification 8 17 2.092302980862508 0.0364114212356729 6.451456310679611 16.274271844660195 1.1227269321938518 0.3276999393402902 3.140724178369711 2.4155680760400804 1.043634905787503 0.3148370578580727 0.1242277571798244 1.0 1.0 0.2920005997725598 0.0049481295197396 +Toe walking 16 25 2.0910800563892846 0.0365208881697303 6.740291262135922 22.805825242718445 1.1386089770349623 0.3130572717722256 3.272869930973316 2.572476621751866 1.068544148592376 0.2998505070337083 0.053596476867868 0.0257915242502586 0.0891217330395956 0.1279773017110395 0.0111707611872444 +Slender long bone 7 15 2.088730775128876 0.0367319649198789 3.817961165048544 13.679611650485436 0.706825571967051 0.4485272038805006 1.94670937649925 2.357444692936107 0.8668756215633454 0.3113769107059386 0.0209197674126672 0.0148056693212618 0.0532804729840314 0.0133642522995781 0.0356460972875996 +Abnormal tongue physiology 7 20 2.0798152449476177 0.0375424822574124 3.9635922330097086 17.96359223300971 0.3695935220217066 0.5570153788195125 2.024398438452662 1.7848158668014682 0.8056116002465731 0.3030294487146113 0.0129229397102748 1.0 0.2780273254227372 0.0458410907711806 0.0008750939624126 +Stroke like episode 3 5 2.0733227341403637 0.0381422543207454 1.9320388349514563 5.347087378640777 0.7802983779647638 0.3377286829697849 1.3402806250303152 1.5433591727314462 1.1185957061594276 0.2970042406174105 0.080387296353503 0.0802348466038066 0.0117676307173903 0.0635022977163126 0.0079370796506279 +Hemiparesis 6 19 2.07228416147228 0.0382389486099457 4.492718446601942 16.453883495145632 0.5632847994166561 0.5250125610456521 2.3039529956499933 2.7457486053720115 0.80325121159606 0.3108877318797908 0.0864414912540909 0.2560754722464486 0.1170412325774002 0.1804107268936248 0.0256930133995238 +Titubation 3 10 2.07208098734445 0.0382578890955422 2.599514563106796 9.50485436893204 0.8889130939576884 0.3308087591435744 1.604695705746215 1.3081060674295342 0.9871075455281332 0.281746434203515 0.0173221540664081 0.0937235599037543 0.0161297090986061 0.0120645849010356 0.01439805670462 +Astrocytoma 1 8 2.067851412514886 0.0386539974575395 3.063106796116505 8.995145631067961 -0.0406188385045949 0.4101166468994238 2.099675901539857 2.070358471881757 1.2750952497401025 0.3317381378473951 0.143947183263572 0.0060718409625537 0.0228441699597423 0.1154739846724814 0.3271248077551284 +Episodic vomiting 5 12 2.062135482312906 0.0391948390603473 4.179611650485437 11.12378640776699 1.060494846441687 0.2663322982599159 1.9809215871966128 1.7630834730718608 1.1982900451883365 0.2840581402107739 0.0103783368032829 0.0100088432903632 0.0033713986773027 0.0391216296567294 0.0033472823991884 +Frontotemporal dementia 3 9 2.060005496969554 0.0393980153161135 3.4344660194174756 10.344660194174756 0.5931524822816645 0.4529040772840182 1.8896952177098856 1.3751065734754873 0.9402199282689112 0.308701646569884 0.1636169873806569 1.0 1.0 0.1318172807011351 0.0353483729682259 +Left ventricular systolic dysfunction 1 6 2.05863239599937 0.0395294668977279 2.0024271844660193 6.274271844660194 0.8306323903703577 0.3188570764916028 1.4472920586220064 1.367095356040773 1.072243004538969 0.2702909744520516 0.1248348676040813 0.1026081339138497 0.1951188871774342 0.099708835751112 0.2906426697670494 +Abnormality of the parathyroid morphology 1 7 2.055900807225888 0.0397920783059955 1.9951456310679612 5.54126213592233 0.174968201326553 0.3509598237346392 1.2385301843824976 1.1216087437262623 1.374717808134014 0.307204091695738 0.080387296353503 0.0030581061915538 0.0117676307173903 0.0635022977163126 0.1992011927715255 +Bruising susceptibility 9 32 2.042667251416523 0.0410853887777877 6.973300970873787 29.92233009708738 0.7164216438132665 0.4493299188905011 2.7915903141815184 3.5959505822612523 0.9221467384175908 0.3249127615519124 0.0563886625875673 0.3837329617083285 0.0714976342214103 0.0326265938094087 0.0486153614380544 +Cachexia 6 19 2.0410341249564925 0.0412474352911274 4.371359223300971 18.25485436893204 0.1308736058795594 0.3437329688633732 1.963367203014057 1.8448565940413904 1.2969303512721055 0.2680999243445657 0.0096838546809454 0.0015459220949256 0.0108633849740392 0.0272622697998741 0.0071658996193174 +Amyotrophic lateral sclerosis 5 15 2.040681985635904 0.041282447077461 4.453883495145631 16.203883495145632 1.0855969203541704 0.3037117925086244 2.3812188822255287 1.5445439412417563 1.0118111691913367 0.2917679915833991 0.0269032788732861 0.1828652209005429 0.3329579057594876 0.0173259681631819 0.0135772679757234 +Kyphosis 31 155 2.03954968288333 0.041395198002192 29.929611650485437 145.9878640776699 0.3337202935488039 0.7323725070888106 9.39233300445956 15.462838267358809 0.6349532376126086 0.3192536742406162 0.1020833384445377 0.0355011314302869 0.0742724104363292 0.0744172957772503 0.0025548113950988 +Abnormality of corneal stroma 5 14 2.039406845322476 0.0414094397964837 4.733009708737864 13.131067961165048 0.6716440045814968 0.2233795964932449 1.7589100966397004 2.506749302052849 1.61853564814875 0.2527544669587041 0.0823964526633588 0.0337662417977069 0.1138374922433585 0.1743155882100804 0.0659378334998033 +Abnormality of lysosomal metabolism 3 5 2.039371439812015 0.0414129705880335 2.0509708737864076 4.776699029126213 0.6001877831871685 0.2139165882109918 1.054267347463803 0.832379194243084 1.5763659100060583 0.2506311014666729 0.0246179943383446 0.0432957136582515 0.0849171013653387 0.1995721086637891 0.00771353919978 +Abnormality of the lymphatic system 39 170 2.036140652310773 0.0417362336295132 29.699029126213592 145.21601941747574 0.1994066708674118 0.5892027724934705 8.709814742221091 14.879269336886908 1.105110161252099 0.3641956683310547 0.111961510018921 0.020094094665229 0.0675344486989955 0.2817172765400834 0.000813686889071 +Oromandibular dystonia 3 6 2.0330787689008 0.0420445656021022 1.730582524271845 4.956310679611651 1.1882502597012077 0.2382412593757527 1.131086190944388 1.1979083634266432 0.9893427275402558 0.2482274576089271 0.0062575921898502 0.066549445548378 0.1289666473793992 0.0042908003473226 0.0037486095651754 +Lower limb spasticity 27 87 2.0317810544169057 0.0421758259974547 17.24271844660194 80.34466019417475 0.5234592060757025 0.5553383930423336 6.384471482056576 8.884788223572686 0.9712236167697867 0.3629508150226985 0.0337600963944998 0.0123908101066582 0.0345222928223586 0.0365475074602906 0.034645054264992 +Subcutaneous hemorrhage 12 44 2.030946528361373 0.0422604191460225 8.720873786407767 39.286407766990294 0.5688424989552578 0.5251816374067695 3.3943487033586366 5.138896949068307 0.8078391480620271 0.32684037849617 0.0946904924690251 0.4974171799485529 0.1558849497402792 0.1248451541149027 0.0381585646670051 +Goiter 2 7 2.0254267290472123 0.0428235651249027 2.6844660194174756 8.25242718446602 0.6101001322888668 0.361705743263382 1.3785638567356056 1.7624367872817217 1.1902904119866486 0.3002320766724904 0.0546260884931124 0.0100088432903632 0.0368247433715485 0.0391216296567294 0.1897708582520546 +Abnormal pupillary function 2 7 2.023150516476105 0.0430576316311384 1.7985436893203883 6.25 0.9459174425459445 0.2892194993230557 1.1928988171245156 1.7202745886032773 1.109204161812943 0.2732247962160634 0.2144776286214526 0.141543756104335 0.2636091346473535 0.1746199077901094 0.1897708582520546 +Thin ribs 2 14 2.02135998311539 0.0432425139916581 3.4101941747572817 12.966019417475728 1.1546097093245242 0.318018636886438 1.686379750034164 1.4240686548069037 0.806693252185275 0.2897104943533539 0.0636918076451499 0.0005458668398673 0.0040346592713098 0.0458410907711806 0.0743636419116672 +Progressive spastic quadriplegia 3 9 2.02064254898978 0.0433167809975645 2.6407766990291264 8.094660194174757 0.8041722661618813 0.2980182786117089 1.3079619433616207 1.0302561803519357 1.23715789109981 0.2930725496255146 0.0302121860941904 0.0479914252810258 0.004071454093033 0.0234889728544392 0.0106255777102749 +Focal t2 hyperintense brainstem lesion 6 19 2.0189927277806525 0.0434879753634094 5.745145631067961 17.558252427184467 0.7787968952644161 0.3563659539921697 2.720936576360794 2.4403574571781053 1.1656572167307155 0.3009968442621839 0.0103783368032829 0.141543756104335 0.0368247433715485 0.0391216296567294 0.0005860509424053 +Abnormality of long bone morphology 47 185 2.018956267240332 0.0434917651519572 33.96844660194175 171.84223300970874 0.2551352842634043 0.7879833166431259 10.273515507747351 21.049683780206234 0.6269466721790355 0.3052369450718564 0.2747597064819623 0.050587552608936 0.2926633063951551 0.2673406502345898 0.0173002148201619 +Severe short stature 7 24 2.0178668329686067 0.043605132116433 5.997572815533981 23.890776699029125 0.6572048998571618 0.4085599295800764 2.761119431778089 3.4934352273944844 1.0243280415736038 0.3082890569118746 0.0824529623114899 0.0077423266249519 0.047891776654715 0.0521205227118809 0.0482032035846316 +Abnormal macrophage morphology 4 6 2.012351440838894 0.0441829034313325 2.9150485436893203 5.640776699029126 -0.1129741045260028 0.144980672561322 1.3090672390975422 1.117854819168669 1.9286041303300476 0.1913667515871486 0.0092378701630156 0.0756950383436983 0.1459927402947744 0.0569248849368824 0.00630824692371 +Personality changes 6 16 2.006877194828556 0.0447627406567818 4.235436893203883 16.20873786407767 0.716641708966708 0.4361664780008399 2.2513009299259603 2.2727002372019856 0.9467269936740988 0.3182188186141179 0.0891131695867488 0.0148056693212618 0.0060217503205503 0.0649283885443843 0.0094203676276074 +Disproportionate short limb short stature 11 24 1.997602680743904 0.0457597523951278 6.587378640776699 19.902912621359224 1.344701363676014 0.2682000023842777 2.8599402401133336 3.1206003999939886 0.9439707190715964 0.2973700803613334 0.0411708722095805 0.0437266531990119 0.0289872856979344 0.0249977551762954 0.0168669379700177 +Arthralgia 8 36 1.9970609247857367 0.0458185650562599 8.067961165048544 33.66019417475728 0.4973169065736986 0.5336317295986659 3.339269543758109 3.852381429809718 0.8994568503620952 0.3283969638661596 0.1436054988198335 1.0 0.2534337902681366 0.4367596009092198 0.0512875926903305 +Muscle hypertrophy of the lower extremities 1 9 1.9961706623764837 0.045915349637174 2.0558252427184467 8.055825242718447 0.5668750819760063 0.4584615762503552 1.6203469748712638 1.290100488501096 0.8942414668325795 0.296643114491846 0.1837253366971717 1.0 1.0 0.1486468007453543 0.3982984602367481 +Morphological abnormality of the pyramidal tract 9 20 1.9961008126196085 0.045922950610526 5.978155339805825 21.21359223300971 0.941567362517309 0.4190895040605777 2.5839325217273803 2.130000617333851 0.9433759961177594 0.3444076850385922 0.5032372962853524 0.2560754722464486 0.4473868461248688 0.4328786381018912 0.1662439638353797 +High frequency sensorineural hearing impairment 2 5 1.995695668922804 0.0459670588051843 1.6650485436893203 4.043689320388349 0.9386965591020852 0.2149168047575724 0.8809977505524413 0.5895810431067134 1.3383980938857114 0.231944191038228 0.0002072945122892 0.0242848323540905 0.0480955538847994 0.0056579443580751 0.0010631590368518 +Abnormality of the metacarpal bones 13 39 1.993858291041129 0.0461675431647214 9.970873786407768 38.182038834951456 0.4116543346986008 0.5294907145512918 4.0672891443896795 5.211392274180197 0.9243684156151686 0.3316769033872264 0.3761180467996454 0.1569435616805101 0.4141001289613655 0.4690969643187369 0.2672785983120794 +Decreased number of peripheral myelinated nerve fibers 3 17 1.9878626506476385 0.0468268824574631 4.269417475728155 15.449029126213592 0.5470641849851599 0.5309325631616826 2.362271543479177 2.3749959691588103 0.7924715482597077 0.3124068087690249 0.6298845018922031 1.0 1.0 0.5797145893212095 0.0883244440970635 +Abnormal larynx morphology 8 34 1.9869585892046704 0.0469269860512537 6.839805825242719 27.718446601941743 0.5738284857128313 0.4761706892213789 2.8749956456134265 3.1319446353032743 0.987106786856402 0.3377886307734372 0.0736485512534826 0.4047844567784328 0.6466300668671063 0.2545314791993786 0.0693354775232653 +Vascular neoplasm 13 36 1.985009019659467 0.0471434679984124 7.924757281553398 36.20388349514563 0.3258157858828113 0.6059539058091996 3.6279214795080814 4.218795722199633 0.7682389896955812 0.3040770756760007 0.1061949323461988 0.1106003446312499 0.315260036101858 0.0645144646592173 0.111596544082692 +Neoplasm of the adrenal cortex 1 5 1.9808088826584256 0.0476127103007741 1.9029126213592231 5.502427184466019 0.279284275131131 0.3518731642920829 1.1804603603119783 0.9766665776615882 1.363400785954724 0.3120205744103949 0.080387296353503 0.0030581061915538 0.0117676307173903 0.0635022977163126 0.1992011927715255 +Nasogastric tube feeding in infancy 4 11 1.9803901168347664 0.0476597096309383 3.0097087378640777 8.495145631067961 1.0003947416243104 0.2675726652756056 1.510449978803449 1.1668877069106371 1.1016283190777107 0.2724768109071007 0.1939099208334744 0.1330370821365251 0.2489059409173845 0.157217223036351 0.012033886898071 +Impaired social interactions 11 53 1.9780681377857292 0.0479210204229609 12.00242718446602 47.49029126213592 0.5604537103987376 0.5219910099489533 4.425488172516818 5.269200019661922 1.0091183008466462 0.3500212759055819 0.0081120000063833 0.3988427362229673 0.2680066972469274 0.0401462700952276 0.0014140057764771 +Proximal tubulopathy 9 24 1.974974308604796 0.048271063615298 7.269417475728155 23.25 0.6812729764745832 0.3939568357360496 3.269858916003623 2.8782959157530654 1.2124757185225692 0.3205652179980567 0.006650732459586 0.0187248462666395 0.0085040146639909 0.0203336527808929 0.0009526402681126 +Motor neuron atrophy 8 21 1.971991887558863 0.048610532615315 5.410194174757281 22.424757281553397 0.8356342611289532 0.3959768073616548 2.754377444710008 1.6813276911909307 0.954775311801755 0.3176984078794489 0.0125029423927421 0.2183837422916212 0.3898210156705143 0.0332787643737564 0.0100459976774882 +Abnormal brainstem mri signal intensity 7 23 1.9711487554833025 0.0487068633656073 6.252427184466019 20.32281553398058 0.9466857218441096 0.334812084954676 2.9078682900486936 2.582646312540884 1.1241621585657078 0.2967087697298931 0.0191264760349916 0.1665759675679584 0.0507931717892238 0.0608575356821196 0.0003278164997314 +Alopecia totalis 0 6 1.9682164721452011 0.0490431357751717 1.577669902912621 5.660194174757281 0.2360895211572874 0.4301462635410513 1.3973923036353155 0.7078395690409284 1.0489709738148425 0.2683714195722722 0.2680241895411663 0.0526645480715484 0.1027954944442906 0.2382253475836706 0.4223814846322101 +Abnormality of skull ossification 4 13 1.9676538539296264 0.0491078787731438 4.366504854368932 12.970873786407768 1.1881205011944458 0.2637442069575459 1.99249670608582 1.4511884027191762 0.8848235988748787 0.2626440236811827 0.0023575401550776 0.0119629297909749 0.0003222994847708 0.0013008093576653 0.0231294135439989 +Spastic diplegia 4 23 1.962795949716742 0.0496698886342898 3.895631067961165 23.512135922330096 0.4881901673150915 0.5457106455963695 2.4507340568260787 1.7101491165809477 0.7349262396464908 0.3064365337981491 0.014331659651373 0.0119629297909749 0.0435975481844182 0.0090567827451286 0.0231294135439989 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..591b3a7695a2c25a1667e1fa5c138cf3c5a4192d --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 4646, + "title": "Average number of proteins per term", + "value": 25.059621179509254 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c70be8768cce2a2dbc90de0af5e5662fd2ad6fcf --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7210bb0edb54686874ec985d44dae22d257c6d83 --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,1980 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Cognitive impairment 0.4501232950707365 4.333434020881012 1.4680129079014392e-05 0.0659304513724544 0.0150550395578221 176 Q9BQE5,Q13315,P06865,Q9Y2R0,P06280,P50897,Q99720,P21964,P00403,P04062,O95831,O75306,Q10713,P07602,P16278,Q9Y619,Q9Y487,Q9NZ08,Q14108,Q9Y287,P04350,P42858,P17900,Q9NPL8,P31483,P03886,Q06787,P05067,Q9NZJ7,Q13535,Q6DKK2,O95470,P54802,P12235,O75569,P22626,P42345,Q9Y2Z2,O76024,Q96RL7,Q6PGP7,O75503,P35637,P13473,P14854,O15118,P01889,P27544,Q13510,O60313 50 +Mental deterioration 0.5037557911938082 4.164688220613184 3.117783272266195e-05 0.134851810139294 0.0150550395578221 100 Q9BQE5,P06865,P50897,P21964,P00403,P04062,O75306,Q10713,P07602,P16278,Q9Y487,Q9Y287,Q14108,P04350,P42858,P17900,Q9NPL8,P31483,P03886,Q06787,P05067,Q9NZJ7,O95470,P54802,P22626,O76024,Q96RL7,O75503,P35637,P14854,O15118,P27544,Q13510,O60313 34 +Dementia 0.5543155634142428 3.7329375027682743 0.0001892595670041 0.5849611575079509 0.015082090110912 58 P61916,P06865,P00403,P04062,P07602,Q9Y487,O43681,Q14108,Q9Y287,P04350,P42858,P17900,P31483,P03886,Q06787,P05067,Q9NZJ7,P22626,O76024,Q96RL7,P35637,O15118,P27544,Q13510,O60313 25 +Dysphagia 0.4412912408663385 3.711310935793693 0.0002061886421775 0.6163602065777041 0.0152055941516994 137 O75874,P61916,P48735,Q99720,P04062,O75306,P07602,Q14108,Q96D71,Q15067,P04350,P42858,P55011,P03886,Q06787,P05067,P15586,Q9NZJ7,Q99519,O75569,P12235,Q8IZA0,Q14739,O76024,Q96RL7,P35637,O15118,P01889,Q9UHX1,Q13510,Q9NR77,O60313 32 +Contractures of the joints of the upper limbs 0.5062735023484154 3.6657147082546655 0.0002466487728789 0.6821168902493613 0.0155874522355314 73 Q7LGA3,Q6DKJ4,Q15392,Q99720,O75844,P23786,P37268,Q99567,Q9Y619,P42892,Q96L58,Q13535,Q8IZA0,Q96AY3,P16435,P48651,P35637,Q9NR77,O60568 19 +Abnormal vertebral morphology 0.4579998008858341 3.662872022611669 0.00024940315855 0.686159879695168 0.0155874522355314 112 O75874,P61978,P48735,P51798,Q13045,Q9UM00,Q9UBN7,O95202,Q6DKJ4,P08236,P04062,O95831,Q32P28,Q10713,Q12768,P16278,Q9Y619,O15228,Q15427,Q9Y4P3,Q14108,Q6NUK1,Q6NUQ1,P15586,Q9UL01,Q99519,Q96L58,O75845,O96028,P54802,O75718,Q14739,P10619,Q8TAA9,Q96HY6,Q96AY3,P16435,Q9UBM7,Q9UHX1,P51812,O60568 41 +Abnormal form of the vertebral bodies 0.4718474866051001 3.661721407139568 0.0002505262139307 0.6877935507298636 0.0155874522355314 88 O75874,P48735,P51798,Q13045,Q9UM00,Q9UBN7,O95202,P08236,O95831,Q32P28,Q10713,Q12768,P16278,Q9Y619,O15228,Q15427,Q9Y4P3,Q6NUK1,Q6NUQ1,P15586,Q99519,Q96L58,O75845,O96028,P54802,Q14739,Q8TAA9,Q96HY6,Q96AY3,P16435,Q9UBM7,Q9UHX1,P51812,O60568 34 +Joint stiffness 0.5491948255544504 3.647463565679012 0.0002648418517605 0.7078880646927048 0.0155874522355314 56 O75844,O75874,Q8TAA9,O76024,Q96AY3,P16435,P48735,P16278,P51648,O15460,P15586,P50402,Q13045,P01889,Q15427,Q9Y4P3,P54802,P08236 18 +Muscle abnormality related to mitochondrial dysfunction 0.6250620431603057 3.6097644994988376 0.0003064751249783 0.7592753831883041 0.0155874522355314 37 O75306,Q9Y6M9,Q9NPL8,Q9NP80,Q86Y39,P03886,Q96CU9,Q9UBX3,P14854,Q9Y2R0,O43676,P12235,O60313,P00403 14 +Optic disc pallor 0.5417543225942982 3.476971496523278 0.0005071117254513 0.905261864941082 0.0193118121020251 50 Q9H061,Q96CU9,P51798,Q92974,O43676,O95831,O75306,Q10713,Q86Y39,Q13277,Q9Y287,Q9Y6M9,Q9NPL8,P03886,Q96L58,Q6P4Q7,Q9UG56,O96000,P04439,O60313 20 +Increased serum lactate 0.4477656042565683 3.465404645529462 0.0005294342344712 0.914599457144151 0.0194043983547091 107 P51970,Q9NP80,Q96CU9,Q9UBX3,Q70HW3,O14949,P00403,Q9P0J0,O95831,O75306,Q99797,Q86Y39,P08574,Q9BWD1,Q9NWS8,Q9NVI7,Q9Y6M9,O75648,P03886,P13073,Q5JRX3,Q00325,P12235,Q9BW92,Q6P4A7,P14854,Q9Y584,P35610 28 +Abnormal vascular physiology 0.5312370793983641 3.4602546733310886 0.0005396647274031 0.918565732095592 0.0194043983547091 56 O75844,P51970,O14678,P03886,P05067,P14854,P01889,Q14739,P06280,Q9NWM8,Q8IZA0,O60568,Q9Y4P3,Q9NZ08,Q14108,P00403,P04062 17 +Abnormality of the cerebrospinal fluid 0.414441925718968 3.4541524211283656 0.0005520252860931 0.9231129357669062 0.01942961726658 157 P51970,P51798,Q7KZN9,Q96CU9,O43676,O95202,Q15392,P21964,P08236,P00403,Q9P0J0,P04062,O95831,P23786,O75306,Q10713,Q12768,P07602,P53701,Q86Y39,O43681,Q9NWS8,Q15427,Q6NUK1,Q9Y6M9,Q9NPL8,P55011,P03886,O15360,Q9NZJ7,Q99519,Q96L58,P13073,O96028,Q16625,Q8TAA9,Q00839,O96000,P16435,P48651,Q9UBM7,P14854,Q8NAT1,Q9NR77,Q14738 45 +Abnormal esophagus physiology 0.3784055006381949 3.4333598100960767 0.0005961504013742 0.9373718659632696 0.0195981660028755 233 O75874,O14678,P61916,P48735,Q13045,P51571,P06280,O95202,Q99720,P21964,Q9UGP8,P04062,O75306,O15269,Q12768,P07602,O15270,Q9Y619,Q9Y4P3,Q14108,Q96D71,Q15067,Q6NUK1,P04350,P42858,P55011,P55795,P03886,Q06787,P05067,P15586,Q9NZJ7,Q99519,Q96PU5,O96028,O75569,P12235,Q8IZA0,Q14739,O76024,Q96RL7,P16435,Q6ZXV5,P35637,O15118,P01889,Q9UHX1,Q9Y584,Q96A33,Q13510,Q9NR77,O60313 52 +Visual loss 0.5317701192735648 3.403378459197383 0.000665580179531 0.9546486372349854 0.0199403671490671 52 O14773,Q10713,P07602,P53701,P03886,O75503,O15460,Q9NZJ7,Q99519,P14854,P01889,P04439,P50897,O60313,P00403 15 +Visceral angiomatosis 0.9973745624270712 3.398325652841282 0.0006779966221959 0.9571924429297648 0.0199403671490671 2 O75874 1 +Lymphangioma 0.9973745624270712 3.398325652841282 0.0006779966221959 0.9571924429297648 0.0199403671490671 2 O75874 1 +Hemangiomatosis 0.9973745624270712 3.398325652841282 0.0006779966221959 0.9571924429297648 0.0199403671490671 2 O75874 1 +Abnormal heart valve morphology 0.453032585745841 3.3906019016941435 0.0006973932273699 0.960883827084341 0.0201247759898184 82 P61978,P51798,P06280,O95202,Q6DKJ4,P21964,P08236,P04062,O75844,Q12768,P37268,P53701,P16278,Q9Y4P3,P55795,Q06787,O15360,Q9UL01,Q96L58,Q96PU5,O96028,Q6PGP7,Q6ZXV5,P01889,Q9UHX1,Q14738 26 +Abnormality of head blood vessel 0.7050800865234247 3.3608923243819273 0.0007769110660456 0.972973345086416 0.0212640594036737 25 P17900,P10619,P07602,P03886,P16278,Q9NZJ7,Q99519,P06865,Q9Y4P3,Q13510,P21964 11 +Abnormality of the optic nerve 0.3659341440053842 3.3598342475298892 0.0007798924770188 0.9733454152322856 0.0212640594036737 262 Q7LGA3,P61978,P38435,O95630,P78318,P51798,Q7KZN9,Q9H061,Q92974,Q96CU9,O15460,P06280,O43676,P50897,Q15907,O95202,P98175,P21964,P00403,P04062,Q9P0J0,P49902,Q9H9P8,O95831,Q96KP1,Q10713,Q12768,P07602,P37268,Q86Y39,O75306,P16278,Q13277,P49770,O43681,Q9NZ08,Q9NVI7,Q9Y287,Q15043,Q15067,P04350,O43292,Q9Y6M9,P55011,Q9NPL8,P42858,O75648,P03886,P61586,Q9NZJ7,Q99519,Q96L58,Q96PU5,O96028,Q6P4Q7,Q9UG56,Q9Y2Z2,Q00839,O76024,O96000,O60762,O14936,Q6ZXV5,Q9UBM7,Q8TCJ2,P01889,Q8NAT1,Q5XKP0,P04439,Q9UHX1,Q96PZ0,P51812,Q9H490,O60313 74 +Corneal opacity 0.5174630261945605 3.3588618321330337 0.0007826418764589 0.9736839906414584 0.0212640594036737 59 Q06136,P06280,O95202,P08236,P04062,O75844,O43683,P53701,P16278,Q9Y4P3,Q9NVI7,Q6NUK1,Q99519,O75845,O96028,O75569,Q16625,P10619,P51648,Q8NAT1,Q13510 21 +Abnormal cellular phenotype 0.3771223507772625 3.305127708866551 0.0009493313218973 0.9878774533970782 0.0241016028499182 199 P51970,P11177,P51798,Q9UBX3,Q7KZN9,Q96CU9,Q70HW3,Q13315,Q9Y2R0,O43676,Q16134,P21964,P00403,Q9P0J0,P04062,O75844,P23786,O14773,O75306,P07602,Q86Y39,Q9UJW0,P09601,Q14108,Q9Y6M9,Q9NPL8,O75648,P03886,Q06787,O15360,P15586,Q9NZJ7,P13073,Q00325,P12235,O43772,Q14739,P42345,Q6PGP7,Q15904,O75503,P35637,Q4J6C6,Q9Y584,Q13510 45 +Sensorimotor neuropathy 0.6299712600309464 3.250198254628381 0.0011532458075864 0.995304130251022 0.0263930583582422 30 Q15120,P07602,P03886,O15270,Q9NZJ7,Q9Y2R0,Q9NR77,O60313,P00403 9 +Abnormal muscle fiber morphology 0.4786464709419986 3.21153483507353 0.0013202796268212 0.9978409177334028 0.0297767919719004 70 P61978,Q70HW3,O43676,Q99720,P00403,O95831,P23786,P50402,Q9H2D1,P31483,P03886,P05067,P51114,P22626,P12235,Q96RL7,P35637,O14979,O60313 19 +Abnormality of the mitochondrion 0.4364395707933745 3.206687165592355 0.0013427292626997 0.9980550365519434 0.0301368123405941 93 P51970,P11177,Q96CU9,Q9UBX3,Q7KZN9,Q70HW3,Q9Y2R0,O43676,P00403,Q9P0J0,O75306,P23786,Q86Y39,Q9Y6M9,Q9NPL8,O75648,P03886,P13073,Q00325,P12235,O43772,P35637,Q4J6C6,Q9Y584 24 +Functional abnormality of the gastrointestinal tract 0.3478150341521134 3.20525352472662 0.001349435641025 0.9981147822096448 0.0301417210971274 288 O75874,P61978,O14678,P61916,P48735,O15460,Q13045,P51571,P06280,O95202,Q01844,Q99720,P21964,Q9UGP8,P04062,P00403,O75306,P08183,O15269,Q12768,P07602,O15270,Q9Y619,Q9Y4P3,Q9NZ08,Q14108,Q96D71,Q15067,Q6NUK1,P04350,P42858,P55011,P55795,P42892,P03886,Q06787,P05067,P15586,Q9NZJ7,Q99519,Q96PU5,O96028,O75569,P12235,Q8IZA0,Q14739,O76024,Q96RL7,P16435,Q6PGP7,Q6ZXV5,P35637,Q5HYI8,O15118,P01889,Q9UHX1,Q9Y584,Q96A33,Q13510,Q9NR77,O60313 61 +Abnormal retinal artery morphology 0.7129371799781461 3.1994080271021645 0.001377101182032 0.9983424613125348 0.0306124980465114 22 P17900,P10619,P07602,P03886,P16278,Q9NZJ7,P06865,Q9Y4P3,Q13510,P21964 10 +Abnormal circulating lipid concentration 0.4419427307336455 3.189365373969269 0.0014258553525789 0.998678848096458 0.0311010514933428 80 P61916,P06280,Q15392,Q8N511,O75844,P23786,P07602,P37268,P50402,P22830,Q9Y4P3,Q9NVI7,P42858,O75648,Q9NZJ7,O75845,O95470,Q15800,O43772,Q14739,Q15904,Q96MF7 22 +Talipes equinovarus 0.4373984781802087 3.179201663104122 0.0014768130649569 0.9989577202552032 0.0319128999990232 81 P61978,Q8TB36,O95202,Q15907,Q15392,P98175,P21964,P08236,P49902,Q9Y619,Q9Y487,Q9NWM8,Q15427,Q6NUQ1,Q9UL01,Q96L58,O75845,O96028,Q96AY3,P16435,Q6ZXV5,Q96A33,Q9NR77,O60568 24 +Limitation of joint mobility 0.4283176481774633 3.153003902796006 0.0016159964629494 0.9994546007681838 0.0336678007482644 103 Q7LGA3,O75874,P48735,O15460,Q13045,P08236,O75844,P23786,P37268,P16278,P50402,Q15427,Q9Y4P3,P15586,Q96L58,Q13535,P54802,Q8TAA9,Q96AY3,O76024,P16435,P48651,P51648,O14979,Q9BT22,P01889,O60568 27 +Cerebral amyloid angiopathy 0.9404900816802804 3.148427722839932 0.0016415131141791 0.999515666220628 0.0337454421613997 2 Q9Y287 1 +Vascular tortuosity 0.9404900816802758 3.148427722839932 0.0016415131141791 0.999515666220628 0.0337454421613997 2 P03886 1 +Asymmetric septal hypertrophy 0.9401983663943952 3.147126881906803 0.0016488339500302 0.9995318889080892 0.0337466190829977 2 P54802 1 +Arthritis 0.5206497124642377 3.118584738146869 0.0018172187883684 0.999786202019032 0.0353423254691253 43 O75844,Q96RL7,P10321,P01889,P06280,Q96HY6,Q9NZ08,Q13510,P21964,Q14108,Q14739,P04062 12 +Abnormality of coordination 0.3218408208672397 3.117213906889164 0.0018256905106737 0.9997944683348118 0.0353423254691253 332 Q9NP80,Q96CU9,O15460,Q13315,O43676,P50897,Q15907,O95202,Q99707,Q99720,O14949,P00403,P04062,Q9P0J0,Q2TAA5,O95831,O14773,O75306,Q10713,P07602,Q86Y39,P16278,Q9Y619,Q9Y487,Q9Y4P3,Q9NZ08,P07437,Q9NVI7,Q14108,Q9Y287,Q15067,P04350,O43292,Q9Y6M9,P55795,Q9NPL8,P31483,P03886,Q06787,P00374,P05067,Q9NZJ7,Q99519,Q6DKK2,O96028,Q5JRX3,O95470,P12235,O60313,Q96RL7,Q6P4A7,O75503,P35637,P14854,O15118,P01889,Q8IV08,Q13510,Q9NR77,P35610,Q14738 61 +Retinal thinning 0.9291131855309176 3.0975457257619063 0.0019513029053814 0.9998854626785836 0.0371547266327965 2 P51648 1 +Skin nodule 0.7064759903299149 3.0942723683393796 0.0019729626952045 0.999896448249014 0.0372617263492692 21 O75874,P48735,P35637,P16615,P06280,Q9NZ08,Q13510 7 +Vascular skin abnormality 0.4089555126623234 3.089957937562823 0.0020018484310886 0.999909477257166 0.0373764671741423 125 Q06136,P38435,Q13315,P06280,P21964,P00403,P04062,O75844,O75306,P53701,P16278,Q9Y487,Q9NWM8,Q15427,P22830,Q14108,P03886,Q9UL01,Q99519,Q96L58,Q13535,Q16625,Q14739,Q8IZA0,P10619,P48651,P51648,P01889,Q13126,O60568 30 +Ventricular arrhythmia 0.5177185912618748 3.0896006108422416 0.0020042581045813 0.999910487049938 0.0373764671741423 43 O75306,P23786,P42892,O43772,Q9HD47,P36551,P03886,Q99959,P13473,P50402,Q14BN4,P10253,P00403,P12235 14 +Heterogeneous 0.5058764057179206 3.0779984806117575 0.0020839597760426 0.9999382353699808 0.037797657809841 47 Q9BQE5,O75844,Q8TB36,P61916,P03886,Q9NR77,Q9Y619,P05067,Q13315,P01889,P12235,P21964 12 +Abnormal activity of mitochondrial respiratory chain 0.4979735961670221 3.0770174788965243 0.0020908304040312 0.9999401798140186 0.037797657809841 54 P51970,Q5JPH6,Q96CU9,Q9UBX3,Q7KZN9,Q70HW3,Q9Y2R0,O43676,Q9P0J0,O75306,Q86Y39,P21912,Q9Y6M9,O75648,Q9NPL8,P82663,P03886,P13073,O96000,Q9Y584 20 +Ketotic hypoglycemia 0.9209451575262512 3.0608250977717697 0.0022072799135468 0.9999652161379512 0.0392912738633666 2 Q13423 1 +Abnormality of extrapyramidal motor function 0.4494727914706799 3.054771734159477 0.0022523187516025 0.9999717967992257 0.0396373974240364 75 P17900,P07602,P98175,P16278,Q06787,P05067,Q9NZJ7,P35637,P06865,Q6DKK2,O75569,Q9Y4P3,P12235,Q99720,O14949,P35610,P04062,Q15043 18 +Alveolar ridge overgrowth 0.9180280046674364 3.04767185311739 0.0023062161490705 0.9999780568258968 0.0398315250133153 2 Q15392 1 +Localized skin lesion 0.3600766776642551 3.036887075547787 0.0023903498675952 0.9999851700202588 0.0410043901641338 230 Q7LGA3,Q06136,O75874,P61978,P38435,P48735,O15460,P16615,Q13315,P06280,O95202,Q6DKJ4,Q15392,P21964,P04062,O75844,O15269,Q15022,O43683,P07602,P53701,O15270,Q9Y619,Q9NWM8,Q15427,Q9Y4P3,Q9NZ08,P42858,O75648,Q06787,O15360,P61586,Q9NZJ7,Q9UL01,Q96L58,Q96PU5,O96028,Q03519,Q03518,Q8IZA0,Q14739,P42345,Q8TAA9,Q96AY3,P48651,Q6ZXV5,Q6PGP7,P35637,P01889,Q13126,Q96PZ0,Q96MF7,Q9UHX1,Q13510 54 +Increased susceptibility to fractures 0.4880868457011532 3.035596813032289 0.0024006014043573 0.999985861412196 0.0410043901641338 59 O75874,Q32P28,O15269,Q96AY3,P16435,P48735,O15270,Q96L58,Q13126,P22626,O75718,Q14108,Q14739,P04062 14 +Variable expressivity 0.4299659910717627 3.0286382377229115 0.0024565865763777 0.9999891064873604 0.041654384065149 80 P17900,P07602,Q6P4A7,P03886,Q9H061,P00374,O76031,Q70HW3,O95470,Q9NWS8,Q15427,Q13510,Q9NR77,P00403 14 +Abnormality of femur morphology 0.4506479208455305 3.027215654979471 0.0024681780277044 0.9999896790003332 0.0416987458789639 74 Q7LGA3,P06280,P04062,O95831,O75844,Q32P28,P07602,P16278,Q9Y619,Q9Y487,Q6NUQ1,Q9NZJ7,Q96L58,O75718,Q14739,Q96AY3,P16435,Q9UHX1,Q96HY6,Q96A33,O60568 21 +Decreased activity of mitochondrial complex i 0.5633668146969484 3.0223172073454365 0.0025084753264377 0.999991445201594 0.0422260013283683 36 O75306,P51970,Q9Y6M9,Q9NPL8,Q86Y39,P03886,Q96CU9,Q9UBX3,Q70HW3,O43676,Q9Y584 11 +Pain 0.3702449734840268 3.018186336743498 0.0025429249304225 0.9999927134206322 0.0424563636292191 183 O75874,P48735,Q15165,Q70HW3,Q13423,P06280,Q01844,P21964,P04062,O75844,P23786,O15269,P07602,O15270,Q9Y4P3,Q9NZ08,Q14108,Q15043,P42892,Q06787,Q9NZJ7,Q9UL01,O75569,P22626,P12235,Q15800,Q14566,Q14739,Q92804,P35637,P14854,P01889,Q96HY6,Q13510,Q9NR77,O60313 36 +Limb joint contracture 0.4184019904657854 3.0161061731970737 0.002560435875949 0.999993284151135 0.0424563636292191 104 Q7LGA3,Q6DKJ4,Q15392,Q99720,Q86XL3,O75844,P23786,P49902,P37268,Q99567,Q9Y619,P42892,Q96L58,Q13535,Q8IZA0,Q96AY3,P16435,P48651,P35637,Q9NR77,O60313,O60568,Q14738 23 +Biliary tract abnormality 0.6115362156922731 3.013119782187138 0.002585768343299 0.999994031641268 0.0426009919254161 29 Q10713,P07602,Q9NZJ7,Q5XKP0,O43681,O95202,Q9UJW0,O96028,P09601,Q14108,Q14739,P04062 12 +Hyporeflexia of upper limbs 0.9072345390898422 2.998826469486664 0.0027102162113341 0.9999966573895256 0.0441812790100298 2 Q9NR77 1 +Mitochondrial myopathy 0.6195953883345889 2.9878788675407115 0.0028092087034132 0.9999978923781946 0.0448698112250357 28 Q9Y6M9,Q9NPL8,Q9NP80,Q86Y39,P03886,Q96CU9,O43676,P12235,O60313,P00403 10 +Abnormality of pulmonary circulation 0.5888147046528958 2.980423722364932 0.0028784991595782 0.999998473895162 0.0453339223572903 31 O75844,Q6NUK1,P51970,O14678,O96000,P03886,P51798,P14854,P01889,Q8IZA0,Q9NZ08,Q14108,P00403,P04062 14 +Hyperesthesia 0.9028588098016244 2.9789438723851127 0.002892437559238 0.9999985698584442 0.0453995435818245 2 P07602 1 +Flaring of rib cage 0.9022753792298626 2.9762893390201093 0.0029175945241433 0.999998728046834 0.0454870609368114 2 P16278 1 +Atlantoaxial dislocation 0.9022753792298636 2.9762893390201093 0.0029175945241433 0.999998728046834 0.0454870609368114 2 Q9UL01 1 +Posterior polar cataract 0.9014002333722266 2.9723059834054606 0.0029557195307581 0.9999989350762868 0.0455502808763488 2 Q9Y287 1 +Abnormal myocardium morphology 0.3649451346342437 2.9674040095651497 0.0030032604289145 0.9999991466896024 0.0455502808763488 186 P48735,Q9H061,Q96CU9,Q13423,P06280,O43676,P08236,P00403,Q9P0J0,P04062,O75306,P23786,Q99797,P53701,Q86Y39,P16278,P50402,Q9NWS8,Q9Y4P3,P10253,Q9NZ08,Q9NVI7,Q14108,Q9Y6M9,Q9NPL8,P03886,O15360,P15586,Q99519,P54802,P12235,Q00325,P22626,O43772,Q9Y2Z2,O76024,Q96RL7,P13473,P14854,P01889,O60313 41 +Skin ulcer 0.5673014744592474 2.9532618601010503 0.0031443510999606 0.9999995578739612 0.0461446034768417 34 O75874,O15269,P48735,O15270,P01889,Q03519,Q8IZA0,Q03518,Q14739,P04062 10 +Micrographia 0.8958576429404801 2.9470346353020886 0.0032083726539233 0.9999996719378552 0.0465075062394792 2 P04062 1 +Elbow ankylosis 0.8952742123687307 2.944370121646482 0.0032361273899668 0.9999997117472484 0.0465075062394792 2 P16435 1 +Humeroradial synostosis 0.8952742123687307 2.944370121646482 0.0032361273899668 0.9999997117472484 0.0465075062394792 2 P16435 1 +Aortic valve calcification 0.9900399942135034 2.941662872322933 0.0032645511758258 0.9999997475154228 0.0465075062394792 3 P04062 1 +Exercise intolerance 0.5753091197075462 2.9281307125563747 0.0034100665118215 0.9999998718729788 0.0465075062394792 32 P23786,P03886,Q9H2D1,Q9Y2R0,P12235,P00403 6 +Decreased palmar creases 0.8891481913652182 2.9163422934289955 0.0035416171832227 0.999999930612557 0.0479718758986967 2 Q9UL01 1 +Abnormal joint morphology 0.3356598043640127 2.914722936401714 0.0035600443992787 0.9999999363252569 0.0480812973228164 288 Q7LGA3,P38435,P10321,O15460,P51571,P06280,O95202,Q6DKJ4,Q15392,P21964,P08236,P04062,Q86XL3,O75844,P23786,P49902,O15269,O95831,P07602,P37268,Q99567,P16278,O15270,Q9Y619,Q9Y487,P50402,Q15427,Q9Y4P3,Q9NZ08,Q14108,Q15043,P42858,Q6NUQ1,P42892,Q9NZJ7,Q9UL01,Q96L58,Q13535,Q96PU5,O96028,O75718,Q8IZA0,Q14739,Q96AY3,Q96RL7,P16435,P48651,Q6ZXV5,P01889,Q9UHX1,Q9Y584,Q96HY6,Q96A33,Q13510,Q9NR77,O60568,Q14738 57 +Elevated pulmonary artery pressure 0.630125290972585 2.9061965659014675 0.003658515424751 0.9999999597691388 0.0489840422576176 26 O75844,Q6NUK1,P51970,O14678,O96000,P03886,P51798,P14854,P01889,Q8IZA0,Q14108,P00403,P04062 13 +Hypertrophic nerve changes 0.8865227537922904 2.9043021068017856 0.0036807280659028 0.9999999637277002 0.0491398350407598 2 Q9NR77 1 +Gastrointestinal infarctions 0.884189031505251 2.8935854444742555 0.003808706479444 0.9999999800299886 0.0501281878286041 2 P01889 1 +Recurrent pharyngitis 0.884189031505251 2.8935854444742555 0.003808706479444 0.9999999800299886 0.0501281878286041 2 P01889 1 +Subcutaneous nodule 0.7324907168492503 2.889367842091524 0.003860172284279 0.999999984291512 0.0502363037332224 17 O75874,P48735,P35637,P06280,Q9NZ08,Q13510 6 +Dysmetria 0.4758326339259495 2.884373593050066 0.0039219317550849 0.9999999882230308 0.050755696195333 58 O43292,O14773,Q10713,Q9NPL8,Q9NP80,Q6P4A7,Q06787,O75503,Q99519,Q6DKK2,Q5JRX3,Q9Y4P3,Q8IV08 13 +Abnormal retinal vascular morphology 0.4827989240774846 2.8747164516940944 0.0040439048115143 0.9999999933328468 0.0519005020836903 51 P17900,P10619,P07602,P38435,P03886,P16278,Q9NZJ7,Q99519,P06865,P04439,Q9Y4P3,Q13510,P21964 13 +Hypertrophic cardiomyopathy 0.4018226238600317 2.871432832617573 0.0040861560821219 0.9999999945255472 0.0519296918612285 116 Q9H061,Q96CU9,Q13423,P06280,O43676,P00403,Q9P0J0,O75306,Q99797,P53701,Q86Y39,P16278,P50402,Q9Y4P3,P10253,Q9NVI7,Q9Y6M9,Q9NPL8,P03886,O15360,P15586,P54802,P12235,Q00325,P13473,P14854,P01889,O60313 28 +Prominent sternum 0.8792298716452627 2.870767822185539 0.0040947615944268 0.9999999947409683 0.0519296918612285 2 P16278 1 +Abnormal bone structure 0.3580578523772139 2.867530127002643 0.004136894156147 0.9999999956794184 0.0521109290912174 188 O75874,P61978,P38435,P48735,P06280,O95202,Q15392,P08236,P04062,Q86XL3,O75844,O95831,Q32P28,P07602,P16278,Q13277,Q9Y619,Q9Y487,Q9NWM8,O15228,Q9Y4P3,P42695,Q14108,Q15043,O43292,O15360,Q9NZJ7,Q99519,Q96L58,O75845,O96028,P54802,P12235,O75718,P22626,Q14739,Q96AY3,P48651,Q13126,Q96HY6,Q13510,O60568 42 +Phenotypic variability 0.4074809829081237 2.854934550216903 0.0043045698780967 0.9999999980240156 0.0534053280024027 104 Q8TD16,P46976,P36551,O00217,Q9H061,Q70HW3,Q8NI60,O43707,P50995,P00403,Q9BYI3,Q8TB37,P07602,P11166,Q5T160,P52701,Q9UEY8,Q9NWS8,Q15427,Q13813,Q92733,P21912,P04350,P17900,Q5TBB1,P03886,P43243,Q06787,P00374,Q9H9S5,Q9NZJ7,O95470,P49792,Q6P2Q9,O60762,Q6P4A7,O14979,O76031,Q13885,Q13510,Q9NR77,O60313,Q9BV79 43 +Abnormal biliary tract morphology 0.6231479489187998 2.8547810246125103 0.0043066511298521 0.9999999980431122 0.0534053280024027 26 Q10713,P07602,Q9UJW0,P09601,Q14108,Q14739,P04062 7 +Abnormality of the vasculature of the eye 0.4323411454060131 2.8335534893470182 0.0046033603204134 0.9999999995099876 0.0564019355491832 75 P17900,P10619,P07602,P38435,P03886,P16278,Q9NZJ7,Q99519,Q13315,P06865,P01889,P06280,P04439,Q9Y4P3,Q9NZ08,Q13510,P21964,Q14739 18 +Caudate atrophy 0.8693115519253221 2.82494939871116 0.0047288083306238 0.999999999727165 0.056917211150462 2 Q96RL7 1 +Positional foot deformity 0.404976910673588 2.811053553073225 0.0049379566227722 0.999999999897235 0.0592809986289408 103 P61978,Q8TB36,O95202,Q15907,Q15392,P98175,P21964,P08236,P49902,Q9Y619,Q9Y487,Q9NWM8,Q15427,Q9NVI7,Q6NUQ1,Q9UL01,Q96L58,Q13535,O75845,O96028,Q96AY3,P16435,Q6ZXV5,Q9UHX1,Q96A33,Q9NR77,O60568 27 +Reduced visual acuity 0.3914650907370219 2.7988229160287283 0.0051289257004674 0.999999999957872 0.0610999712932605 124 P51798,Q9H061,Q92974,Q96CU9,Q96S66,P06865,P68371,O43676,P50897,Q99707,P49327,O75306,Q10713,P07602,P53701,Q86Y39,P16278,P36776,Q13277,P49770,O43681,Q9NZ08,Q6YHK3,P21912,Q15043,P17900,Q9Y6M9,Q9NPL8,P03886,Q9H9S5,Q9H2P0,P61586,Q9NZJ7,Q6P2Q9,Q9P032,O96000,Q07021,P01889,Q9UHX1,O43505,Q96MF7,O60313 42 +Cherry red spot of the macula 0.8476820596822398 2.797631635774786 0.0051478785626517 0.9999999999614404 0.0611689099797443 10 P10619,P17900,P07602,P16278,Q9NZJ7,P06865,Q13510 7 +Abnormality of fontanelles 0.4785998506504287 2.7861446707852 0.0053339060539323 0.9999999999838266 0.0613399196202221 46 O75844,P42345,Q32P28,P16435,Q9Y619,Q9Y487,Q9UL01,Q13535,O15228,O75718,P98175,Q14738 12 +Progressive neurologic deterioration 0.6597217933427337 2.7848330328627284 0.0053555292583731 0.9999999999853804 0.0614365158874112 21 Q9NPL8,Q10713,P07602,P16278,P54802,Q9Y287,P04062 7 +Splenomegaly 0.405419581562366 2.7790045898222617 0.0054525754661003 0.9999999999907092 0.0622424216597105 96 P61916,P36551,P51798,Q13315,Q15392,Q9H0U3,P21964,P08236,P04062,Q96J02,Q10713,P07602,P16278,P28288,P10253,Q9NZ08,Q14108,Q6NUQ1,P15586,Q9NZJ7,Q99519,P54802,Q16625,Q14739,Q96RL7,O60762,O14936,Q14376,Q15904,Q6PGP7,Q9BT22,O15118,P01889,Q96HY6,Q96A33,Q13510 36 +Blindness 0.407394378103329 2.7670638194920936 0.0056563680928591 0.9999999999964144 0.0642530223946792 81 P51798,Q96CU9,P06865,O43676,P50897,Q99707,P49327,O75306,P07602,P53701,Q86Y39,P16278,P36776,P49770,Q9NZ08,Q6YHK3,P21912,P17900,Q9Y6M9,Q9NPL8,P03886,Q9H9S5,Q9NZJ7,Q6P2Q9,Q9P032,O96000,Q99496,P01889,O15078,O43505,Q96MF7 31 +Osteopenia 0.4167950997990169 2.7566162487630246 0.0058402848718446 0.9999999999984818 0.0656996695268526 78 O75844,Q32P28,O43292,P61978,Q96AY3,P07602,Q9Y487,Q9NZJ7,Q96L58,Q13126,Q9NWM8,O15228,Q9Y4P3,O75718,Q14108,O60568,P04062 17 +Abnormal circulating cholesterol concentration 0.5432782909838184 2.7453809325213347 0.0060440695427701 0.9999999999994142 0.0670184894885682 34 P42858,P37268,P07602,P61916,Q15904,Q9NZJ7,P50402,O75845,Q15392,Q15800,Q8N511,Q9NVI7,Q14739 13 +Aplasia hypoplasia of the skin 0.4615230367803035 2.734505167921923 0.0062474114674009 0.9999999999997736 0.068618141081666 59 O75844,P53701,P48651,Q6ZXV5,Q06787,Q9Y619,Q9UL01,Q13315,Q96L58,Q13126,Q9NWM8,Q96PU5,O96028,Q15392 14 +Increased csf lactate 0.4689150420069071 2.7240800698151104 0.0064480871747316 0.9999999999999114 0.0701245405328358 51 P51970,Q9Y6M9,Q9NPL8,Q86Y39,P03886,Q96CU9,P14854,P13073,O43676,Q9NWS8,P00403,Q9P0J0,O95831 13 +Hip osteoarthritis 0.8474329054842502 2.7230087557785247 0.0064690343355542 0.9999999999999196 0.0701245405328358 2 P01889 1 +Corticospinal tract hypoplasia 0.8459743290548414 2.7161698293173586 0.0066042031129032 0.9999999999999574 0.0703741460150191 2 P11177 1 +Chondrosarcoma 0.9355121097169448 2.7121951321923685 0.0066839233443143 0.9999999999999706 0.0708984197664027 3 P48735,O75874 2 +Clumsiness 0.6472570451953085 2.70053879695412 0.0069227262348841 0.9999999999999905 0.0722020699105614 21 P42858,O14773,P31483,P07602,O75503,Q9NZJ7,Q13510,Q9NR77,Q15067 9 +Platyspondyly 0.5327925303207695 2.7004362641199977 0.0069248603994775 0.9999999999999905 0.0722020699105614 35 O75874,Q32P28,Q96AY3,P48735,P16278,Q96L58,Q96HY6,P08236,O60568,Q14739,O95831 11 +Muscle weakness 0.3212219695525268 2.7001342515285587 0.0069311500602906 0.9999999999999908 0.0722020699105614 300 P51970,P61978,Q15120,Q8TB36,Q9NP80,Q15165,Q96CU9,O15460,Q70HW3,P06865,O43676,Q99720,Q9BQT8,P00403,Q9P0J0,O95831,P23786,O15269,O75306,Q10713,P07602,Q86Y39,O15270,P50402,Q9NWM8,P10253,Q15043,Q15067,P42858,P17900,Q9Y6M9,Q9NPL8,P31483,P03886,Q06787,P00374,Q9NZJ7,Q9UL01,Q99519,Q6DKK2,P13073,P51114,P22626,P12235,Q14739,Q92804,Q96RL7,P48651,P35637,P13473,O14979,P14854,P01889,Q13126,Q8NAT1,Q4J6C6,Q9UHX1,Q13510,Q9NR77,O60313 60 +Abnormality of the ribs 0.4470793569730532 2.6902598124834705 0.0071396409525468 0.9999999999999966 0.0738495193874049 66 P51798,Q9UM00,O95202,Q6DKJ4,O95831,O75844,Q32P28,Q12768,P16278,Q9Y619,Q15427,P15586,Q96L58,Q13535,O96028,P54802,O75718,Q14739,Q8TAA9,P16435,P48651,Q9UBM7,Q9UHX1,Q96HY6 24 +Diffuse cerebral atrophy 0.6807239408782695 2.6896415383632664 0.0071528806983065 0.9999999999999968 0.0738495193874049 18 P16278,Q06787,Q10713,P07602 4 +Recurrent fractures 0.5366891759260238 2.68757785495968 0.0071972321937461 0.9999999999999972 0.0739786300268684 34 O75874,Q32P28,P16435,P48735,Q96L58,Q13126,O75718 7 +Abnormal cornea morphology 0.3676271307148059 2.685555133512919 0.0072409427256561 0.9999999999999978 0.074263620095802 162 Q7LGA3,Q06136,Q92974,Q13045,P06280,O95202,P21964,P08236,P04062,Q2TAA5,O75844,O43683,P53701,P16278,Q9NWM8,Q9Y4P3,Q9NZ08,P07437,Q9NVI7,Q8N201,Q6NUK1,P42858,O75648,O15360,P61586,Q9UL01,Q99519,Q96L58,O75845,O96028,O75569,P12235,Q16625,Q14739,P10619,P51648,P01889,Q96PZ0,Q8NAT1,Q13510,Q14738 41 +Abnormally lax or hyperextensible skin 0.4770330161755118 2.6783412890183467 0.007398778687343 0.999999999999999 0.0745655656863251 43 Q6NUK1,Q15022,O96000,P48651,P38435,Q15904,Q9Y487,Q9UL01,Q96L58,Q9NWM8,Q9UHX1,Q9Y4P3,P07437,P04062 14 +Neuronal loss in central nervous system 0.8053514232975331 2.6748896489876115 0.0074753851384417 0.9999999999999992 0.0751745440545458 11 P07602,P35637,Q9NZJ7,O15118,P04062 5 +Disproportionate short stature 0.5560104910451409 2.656862167529385 0.0078871682492609 1.0 0.0779654972043965 30 Q7LGA3,P42345,Q32P28,Q96HY6,P16278,Q9Y366,Q9UBM7,O15228,Q6DKJ4,Q15392,Q9UHX1,O75718,Q96MF7,Q14739 14 +Supranuclear gaze palsy 0.6562183669194133 2.655310127716776 0.0079235525650231 1.0 0.0781588645798254 19 P07602,P35637,Q9NZJ7,O15118,Q99720,P04062 6 +Abnormal pulmonary interstitial morphology 0.5270670466333007 2.6492291034830457 0.0080675620706354 1.0 0.0790757244307429 35 Q9UJW0,P04062,P09601,Q14108,Q8IZA0 5 +Peripheral axonal neuropathy 0.4537491621575084 2.6447702810644507 0.0081746392541941 1.0 0.0799565767894442 59 O15269,Q15067,P07602,Q96RL7,P03886,O15270,Q8IV08,Q9NZJ7,P22626,Q8TAF3,O60313,Q9NVI7,P12235,P00403,O95831 15 +Angina pectoris 0.918796144872051 2.6406176530816308 0.008275505355404 1.0 0.0806965806052503 3 O75844 1 +Bulbar signs 0.7621814181630865 2.6402276978301376 0.0082850342119467 1.0 0.0806965806052503 13 P07602,P03886,P35637,Q9NZJ7,O43681,Q99720,P04062,Q15043 8 +Negativism 0.9166661012739944 2.631454814020036 0.0085020172131531 1.0 0.0816838186079035 3 Q9BQE5 1 +Bone pain 0.6179637623578044 2.6136220056812114 0.0089588090902106 1.0 0.0844272353612953 23 P07602,O75874,P48735,P04062 4 +Adult onset 0.4406567011280625 2.612087153826898 0.0089991309535053 1.0 0.0844827149675336 66 P36551,P38435,Q07864,Q9H0U3,Q9UGP8,P04062,Q12768,P07602,P43304,P21912,Q16637,P31483,P43243,Q06787,Q9NZJ7,Q9Y4G8,P12235,Q14566,Q9UBS4,P42345,O76024,Q07021,Q04446,O14979,O15118,Q8IV08 26 +Dyspnea 0.3927220899304178 2.610833128991045 0.0090321954641066 1.0 0.0846039921899986 100 P51970,Q15165,P51571,P06280,P04062,O95831,O75844,P23786,O75306,P07602,P53701,Q9Y619,P10253,Q96EY8,P04350,P03886,Q9NZJ7,Q96L58,Q00325,P12235,Q92804,P35637,P01889,Q9UHX1,Q13510 25 +Hyperlipidemia 0.5503568074373744 2.6099471376681307 0.0090556214911352 1.0 0.0846527514040531 30 O75844,P23786,P50402,Q13045,P49257,P06280,P22830,O95470,Q96MF7 9 +Pericardial effusion 0.8979383909712447 2.608169593945607 0.0091027842414574 1.0 0.084922762220505 7 P04062 1 +Abnormal pericardium morphology 0.7739862749745834 2.6046508937919572 0.0091967914421322 1.0 0.0854565860802929 12 P01889,Q9NZ08,Q14108,P04062 4 +Young adult onset 0.7916131423698831 2.6036976325557326 0.0092224079262657 1.0 0.0855235673162286 11 P31483,P07602,P38435,Q9NZJ7,O15118,Q9H0U3,Q14566 7 +Gait disturbance 0.3020634868513674 2.6015617437625416 0.0092800358497882 1.0 0.0857157983262743 337 Q7LGA3,P61978,Q15120,Q8TB36,Q9NP80,Q96CU9,Q13315,Q15907,Q8TAF3,Q99707,Q99720,O14949,P98175,Q9BQT8,P00403,P04062,O75844,P49902,O14773,O15269,Q10713,O95831,P07602,P16278,O15270,Q9Y619,P50402,Q9Y4P3,Q9NZ08,Q96N66,Q14108,Q9NVI7,Q8N201,Q15043,Q15067,P04350,O43292,P42858,P55795,P31483,P03886,Q06787,P05067,Q9NZJ7,Q99519,Q5JRX3,O75569,P22626,P12235,P42345,Q96AY3,Q96RL7,O75503,P35637,P13473,O15118,P01889,Q4J6C6,Q8IV08,Q13510,Q9NR77,O60313,Q14738 63 +Facial capillary hemangioma 0.8191365227537798 2.5893687076521115 0.0096152080968099 1.0 0.0881846618415465 2 P16435 1 +Abnormal sternum morphology 0.378920640257382 2.5727659637900016 0.0100889405099244 1.0 0.0915492531427913 122 Q7LGA3,P61978,O95202,Q6DKJ4,P98175,P08236,P04062,O95831,P16278,Q9Y619,Q9Y487,P50402,Q9Y4P3,P07437,Q9NVI7,P55795,Q06787,Q9UL01,Q99519,Q96L58,O96028,O75718,Q14739,Q96AY3,Q9UHX1,Q96A33,Q13510 27 +Abnormality of upper limb joint 0.3807705705790194 2.570504670250898 0.0101550457509078 1.0 0.0919694786719648 119 Q7LGA3,O95202,Q6DKJ4,Q15392,O95831,O75844,P23786,P37268,Q99567,P16278,Q9Y619,Q15427,Q9Y4P3,P42892,Q96L58,Q13535,O96028,Q8IZA0,Q96AY3,P16435,P48651,Q13510,Q9NR77,O60568 24 +Axial dystonia 0.9021372878542366 2.568701612987063 0.0102080312480146 1.0 0.0922694808915873 3 Q99720 1 +Retrocollis 0.9007878611030002 2.5628505760680276 0.0103816717885627 1.0 0.0925782094619242 3 Q99720,P35637 2 +Abnormality of the parathyroid gland 0.6269369838753364 2.5614634681774415 0.0104232202709129 1.0 0.0927706539821099 21 P03886,O75874,P48735,P00403 4 +Delusions 0.6225960347480828 2.531484479178558 0.0113580844072367 1.0 0.0991910905188381 21 Q9BQE5,P42858,P07602,Q96RL7,P36551,Q9NZJ7,P49770,O43681,P21964,P04062 10 +Concentric hypertrophic cardiomyopathy 0.8923094296271923 2.5260006780967124 0.0115369258573494 1.0 0.0999336322809341 3 P00403 1 +Fatigue 0.3899636253500816 2.520954601287548 0.0117036950863247 1.0 0.1008819431745171 82 P07602,Q9NP80,Q15165,P35637,Q9NZJ7,O15460,Q70HW3,P01889,Q13423,P06280,Q4J6C6,P12235,Q9NZ08,O60313,Q14739,P04062,Q92804 17 +Aplasia hypoplasia of the palmar creases 0.8894076451706907 2.5133537551755105 0.0119589349549746 1.0 0.1025114608871077 3 Q99567,Q9UL01 2 +Peripheral axonal degeneration 0.4077912660769944 2.50876380365482 0.0121154465268213 1.0 0.1032173620839005 75 O15269,Q15067,Q8TB36,P07602,Q96RL7,P03886,O15270,Q8IV08,Q9NZJ7,P00403,Q6DKK2,P22626,Q8TAF3,O60313,Q9NVI7,P12235,Q9BQT8,O95831 18 +Arteriosclerosis 0.7049085308852924 2.5070093185657583 0.0121757501700556 1.0 0.1032173620839005 15 O75844,P38435,P16278,O15118,Q99519,O75845,Q13510 7 +Abnormal csf protein level 0.7376172828661158 2.5043678766272945 0.0122670412190846 1.0 0.1032173620839005 13 P07602,P03886,Q9NZJ7,O43681,Q16625,Q9NR77,P00403 7 +Dermal atrophy 0.5471552031812266 2.498429436859613 0.0124744974670671 1.0 0.1044261535711606 29 O75844,P53701,Q9UL01,Q9NWM8,Q15392 5 +Joint hemorrhage 0.7995915985997494 2.495865730354045 0.0125650152563572 1.0 0.1048062134309437 2 P38435 1 +Dysostosis multiplex 0.7875902968014165 2.4949039069175516 0.0125991244531353 1.0 0.1049023874718046 10 P10619,P16278,P15586,P54802,P08236 5 +Gait ataxia 0.4179555179598255 2.492934376629659 0.0126692259052618 1.0 0.1052973587761121 71 P04350,O14773,O43292,Q10713,P07602,P03886,Q06787,Q9NR77,Q8IV08,Q9NZJ7,O15118,Q15907,P12235,Q9NVI7,Q14108 15 +Small anterior fontanelle 0.8830664015196669 2.4856546114083993 0.0129313401543338 1.0 0.1068355362644688 3 Q9Y619 1 +Abnormality of bone mineral density 0.3640548901017874 2.485268680054937 0.0129453688987337 1.0 0.1068355362644688 145 P61978,P06280,O95202,Q15392,P04062,O95831,O75844,Q32P28,P07602,P16278,Q13277,Q9Y487,Q9NWM8,O15228,Q9Y4P3,Q14108,Q15043,O43292,O15360,Q9NZJ7,Q96L58,O96028,P54802,P12235,O75718,Q14739,Q96AY3,P48651,Q13126,Q96HY6,Q13510,O60568 32 +Osteoarthritis 0.8008614919660755 2.4797470611715076 0.0131475611359743 1.0 0.107921500066673 9 O75844,P01889,Q96HY6,Q14108,P04062 5 +Abnormal arterial physiology 0.5337039556369688 2.4704353348078394 0.0134948714760039 1.0 0.1089811323545772 30 O75844,P05067,P01889,P06280,Q9NWM8,Q9Y4P3,Q9NZ08,O60568,Q14739 9 +Abnormality of the tongue 0.3835893353358497 2.4687199003232476 0.0135597310244739 1.0 0.1089811323545772 99 Q7LGA3,P61978,O15460,Q6DKJ4,P98175,Q9BQT8,O95831,O75844,Q10713,P16278,Q9NWS8,Q9Y4P3,P10253,P04350,Q99519,P51114,Q96RL7,P48651,P01889,Q96A33,Q13510 21 +Centrocecal scotoma 0.8791946308724855 2.4687005539006863 0.0135604640689344 1.0 0.1089811323545772 3 P03886,O60313 2 +Scotoma 0.7824516831039791 2.4685437545367463 0.0135664065577243 1.0 0.1089811323545772 10 P03886,Q9H061,Q9Y287,P04439,O60313 5 +Elbow flexion contracture 0.5434560610176359 2.468005680175638 0.0135868163630155 1.0 0.1089811323545772 29 Q7LGA3,P23786,Q96AY3,P37268,P16435,P48651,Q96L58,Q13535,O60568 9 +Increased serum pyruvate 0.5060924650181242 2.4593619376390228 0.0139184219947554 1.0 0.1109176476631798 35 Q9Y6M9,Q9NPL8,Q9NP80,Q86Y39,P03886,Q96CU9,Q70HW3,Q9BWD1,O43676,Q5JRX3,O95831 11 +Ventricular hypertrophy 0.4763135193162693 2.4562790243319133 0.0140384110092939 1.0 0.1115331171777123 40 O75844,P23786,O43772,P03886,O95630,P14854,P06280,P10253,Q96MF7,P00403,P12235 11 +Retrognathia 0.3847689187837512 2.446302978131751 0.014432965694429 1.0 0.112917582557922 82 Q7LGA3,Q15392,P04062,Q2TAA5,O75844,Q15022,P37268,P53701,Q99567,Q9Y619,Q9UPT5,Q15427,Q8N201,Q9UL01,Q16625,Q96PZ0,Q4J6C6,Q9UHX1,Q96MF7 19 +Horizontal nystagmus 0.5766871975022442 2.437309402079112 0.0147970125072425 1.0 0.1131696579096172 25 O14773,P07602,Q9H061,Q9NZJ7,O60313,P04062 6 +Fasciculations 0.4981241624481129 2.433027941813053 0.0149731453672194 1.0 0.1142286262333362 36 P07602,P35637,Q9NZJ7,P06280,P51114,Q9NWS8,P22626,Q13510,Q9BQT8 9 +Laryngeal dystonia 0.8698570177998208 2.4276817469059284 0.0151956710471712 1.0 0.1157362093199304 3 O75569,Q96RL7 2 +Urinary glycosaminoglycan excretion 0.8576330347584779 2.425591270392804 0.0152834721868213 1.0 0.1162144218984812 7 P16278,P15586,P54802 3 +Parkinsonism 0.5381365702291784 2.4240909713360383 0.0153467605586383 1.0 0.1163149258653081 29 P07602,Q06787,P35637,P05067,Q9NZJ7,O75569,Q99720,P04062,Q15043 9 +Central scotoma 0.8546527521306923 2.4119457419684966 0.0158676426877426 1.0 0.1190970402701977 7 O60313,P03886,Q9Y287,Q9H061 4 +Branchial cyst 0.7820886814468883 2.411299037725263 0.0158958092777896 1.0 0.1191160159751786 2 Q9UHX1 1 +Abnormality of the upper respiratory tract 0.3765551858285447 2.404408826883987 0.0161986463128753 1.0 0.1208008198549261 107 Q15165,O15460,Q13315,P21964,P08236,P07602,P16278,Q15427,Q06787,P15586,Q9NZJ7,Q03519,P54802,Q03518,Q14739,Q92804,P16435,P35637,P01889,Q9UHX1,Q96HY6,Q13510 22 +Follicular thyroid carcinoma 0.7803383897316213 2.4027990719708283 0.0162701243628249 1.0 0.1209455964634954 2 P21912 1 +Abnormal brain choline level by mrs 0.862978029454724 2.3973453912608393 0.0165143486975651 1.0 0.1219803879950522 3 P07602 1 +Reduced brain n acetyl aspartate level by mrs 0.862978029454724 2.3973453912608393 0.0165143486975651 1.0 0.1219803879950522 3 P07602 1 +Abnormal brain n acetyl aspartate level by mrs 0.862978029454724 2.3973453912608393 0.0165143486975651 1.0 0.1219803879950522 3 P07602 1 +Abnormal length of corpus callosum 0.7785880980163407 2.394291238918181 0.0166525201271596 1.0 0.1226111069901487 2 P11177 1 +Optic atrophy 0.3321273045081994 2.3898923504521443 0.0168533118255176 1.0 0.1237614764320258 198 O95630,P51798,Q7KZN9,Q9H061,Q96CU9,O15460,P06280,O95202,P50897,Q15907,P98175,P21964,P00403,Q9P0J0,P49902,Q9H9P8,O75306,Q12768,P07602,Q86Y39,Q5T2R2,P16278,P49770,O43681,Q9NVI7,Q15043,Q15067,P04350,O43292,P51572,P03886,P61586,Q9NZJ7,Q99519,Q96PU5,O96028,Q6P4Q7,Q6P2Q9,Q9P032,Q9Y2Z2,O76024,O60762,O14936,Q6ZXV5,P40855,Q9UBM7,Q8TCJ2,Q9UNW1,Q8NAT1,Q5XKP0,P01889,P51812,Q9H490,O60313 54 +Respiratory distress 0.4362207014667221 2.3897022905159706 0.0168620349938597 1.0 0.1237614764320258 54 P51970,P51571,Q16134,P04062,O95831,O75306,P23786,P07602,P53701,Q9Y619,P10253,Q96EY8,P04350,O75648,P03886,Q9NZJ7,Q96L58,Q00325,O60762,Q9Y366,Q9UHX1,Q13510 22 +Abnormal mitochondria in muscle tissue 0.594032377218016 2.3847961442091505 0.017088587785526 1.0 0.1249926626170312 22 Q9Y6M9,Q9NPL8,Q86Y39,P03886,Q96CU9,O43676,P00403 7 +Abnormality of glycolipid metabolism 0.7967762841008441 2.3825129373533893 0.017194927777097 1.0 0.1250197722259672 8 P17900,P07602,Q9NZJ7,P06865,P06280 5 +Myalgia 0.462319778649973 2.3819343969414466 0.0172219652100911 1.0 0.1250207036970052 41 P23786,Q06787,P14854,Q9UL01,P01889,P06280,P12235,Q9NZ08,P21964,O60313,Q14739 11 +Cervical spine instability 0.7753792298716358 2.378673119719205 0.0173750760201072 1.0 0.1259354183922281 2 Q96L58 1 +Ectopic calcification 0.4326485016237098 2.376917445710903 0.0174579948481854 1.0 0.1261428368035296 57 O75844,P23786,P38435,P03886,P05067,Q99519,Q14739,O15228,O75845,O60313,Q16625,P08236,P00403,P04062 14 +Protrusio acetabuli 0.8567804216145092 2.3699283085408256 0.0177915347121417 1.0 0.128201484342482 3 O75718 1 +Joint contracture of the hand 0.439351765691078 2.368772666625635 0.0178472196267236 1.0 0.128201484342482 47 O75844,P42892,Q99567,Q9Y619,Q15392,Q9NR77,Q8IZA0 7 +Large placenta 0.8564912281261419 2.3686469891639184 0.0178532846253951 1.0 0.128201484342482 3 O75844 1 +Abnormal lower limb bone morphology 0.3393387197993183 2.366638268890368 0.0179504677159407 1.0 0.1285471759493038 180 Q7LGA3,P06280,O95202,Q6DKJ4,Q15392,P98175,P21964,P08236,P04062,O95831,O75844,Q32P28,Q10713,P07602,Q99567,P16278,Q9Y619,Q9Y487,Q9UPT5,Q15427,P42858,O75648,Q6NUQ1,Q06787,O15360,Q9NZJ7,Q96L58,Q13535,P13073,O96028,O75718,Q14739,Q96AY3,P16435,Q8NAT1,Q9UHX1,Q96HY6,Q96A33,Q13510,O60568 40 +Widened cerebral subarachnoid space 0.8558800587567992 2.365938522019874 0.0179844305568332 1.0 0.1285471759493038 3 P00403 1 +Cardiac valve calcification 0.940189098044165 2.3647046013649993 0.0180444571568152 1.0 0.1285805950162018 4 P04062 1 +Mitral valve calcification 0.940189098044165 2.3647046013649993 0.0180444571568152 1.0 0.1285805950162018 4 P04062 1 +Abnormal optical coherence tomography 0.7718786464410564 2.361605042973106 0.0181960161664826 1.0 0.129264053684218 2 P04439 1 +Photoreceptor layer loss on macular oct 0.7718786464410564 2.361605042973106 0.0181960161664826 1.0 0.129264053684218 2 P04439 1 +Submucous cleft of soft and hard palate 0.5749104792403538 2.360769399762519 0.0182370668699951 1.0 0.1293578819511412 24 Q7LGA3,O75844,Q9Y619,Q8NAT1,Q15392,Q14738 6 +Abnormality of fundus pigmentation 0.8518616674904907 2.348110939613601 0.0188689002889013 1.0 0.1315980220884763 3 Q9Y619 1 +Hypopigmentation of the fundus 0.8518616674904907 2.348110939613601 0.0188689002889013 1.0 0.1315980220884763 3 Q9Y619 1 +Smooth muscle antibody positivity 0.7686697782963838 2.3459317114400164 0.0189795844812739 1.0 0.1315980220884763 2 Q96J02 1 +Sensory neuropathy 0.4983667653244613 2.344576427595081 0.0190487060525976 1.0 0.1316968576195964 34 O15269,Q96RL7,P03886,O15270,P22626,Q8IV08,O60313,P00403,Q15067 9 +Abnormality of hepatobiliary system physiology 0.3776028443883565 2.3425570625657675 0.0191521050499636 1.0 0.1322149778040583 82 O15460,Q8N511,P04062,O75306,P23786,Q10713,P08574,Q9Y619,P28288,Q9NWS8,P22830,O75648,Q6NUQ1,P03886,O75845,O43772,Q16625,Q6PGP7,Q9BT22,O15118,Q8TCJ2,P01889,Q5XKP0,Q96A33,Q13510 25 +Hallucinations 0.4363200704070887 2.340649752818157 0.0192502165989669 1.0 0.1326951132326417 48 Q9BQE5,P42858,P07602,O75503,P35637,P05067,Q9NZJ7,Q6DKK2,P50897,P21964,O60313,P04062 12 +Osteolysis 0.5182829911303762 2.3394731709043226 0.0193109585095148 1.0 0.132719989992908 30 O75844,O75874,P48735,P04062 4 +Abnormal response to endocrine stimulation test 0.8495029525550284 2.337630652608539 0.0194064164093987 1.0 0.1330259793538877 3 Q13423 1 +Sea blue histiocytosis 0.8491391887948476 2.3360133274164605 0.0194905469438861 1.0 0.1330259793538877 3 P16278,O15118 2 +Airway obstruction 0.6422388808926768 2.3304395502755217 0.0197829314733677 1.0 0.1345201077292839 17 O75844,P16435,P21964,P06280,P09601 5 +Osteopetrosis 0.8476801867522401 2.3295236779837674 0.0198313401262608 1.0 0.1345201077292839 3 P48651,Q15392 2 +Respiratory failure 0.4219416161803674 2.323791706389645 0.0201366604642916 1.0 0.1357951196188018 64 Q8TD16,O75306,P23786,P07602,P61916,P53701,P43243,Q15165,P35637,Q9Y619,Q9NZJ7,Q9BT22,Q70HW3,Q5XKP0,P10253,Q13510,Q16637,Q92804 18 +Limited elbow movement 0.4693238490295393 2.3236020864780325 0.020146830509182 1.0 0.1357951196188018 39 Q7LGA3,P23786,Q96AY3,P37268,P16435,P48651,Q96L58,Q13535,Q15427,O60568 10 +Abnormal social behavior 0.4022803235548429 2.3232152484012505 0.0201675920225943 1.0 0.1357951196188018 72 Q9Y6M9,Q9NPL8,Q15067,P07602,Q86Y39,P03886,Q06787,Q96CU9,P05067,O43676,Q15907,Q9Y4P3,Q9UHX1,Q9P0J0,Q2TAA5 15 +Biliary atresia 0.7637106184363893 2.3216574366615337 0.0202513885186652 1.0 0.1361620131081314 2 Q10713 1 +Abnormal aortic valve morphology 0.4428406769156189 2.319457644038086 0.0203702351982191 1.0 0.1366599748145725 43 O75844,P61978,P37268,O15360,Q96L58,P01889,P06280,Q14738,Q6DKJ4,Q9Y4P3,Q9UHX1,P21964,P04062 13 +Abnormality of epiphysis morphology 0.4225159187178748 2.318772170382532 0.0204073929281831 1.0 0.1366599748145725 63 Q7LGA3,P38435,P51798,O95202,P08236,O95831,P16278,Q9Y619,O15228,Q6NUQ1,Q99519,Q96L58,Q13535,O96028,Q14739,Q9UG56,P16435,Q9Y366,Q9UBM7,Q96HY6,Q96MF7,O60568 22 +Abnormal rib cage morphology 0.3819862806535256 2.3172678254091146 0.0204891468313037 1.0 0.136967735508255 79 O95202,Q6DKJ4,P08236,O75844,Q32P28,P16278,Q9Y619,Q15427,P15586,Q96L58,Q13535,O96028,P54802,O75718,Q14739,P16435,P48651,Q9UHX1,Q96HY6 19 +Abnormal cartilage morphology 0.7038083127640293 2.3140909688117306 0.0206627327077797 1.0 0.1375344644131012 13 O75874,P48735,Q9UHX1 3 +Mitral stenosis 0.9273128059593352 2.312288980906217 0.0207617635196344 1.0 0.1379959274852955 4 P04062 1 +Arterial rupture 0.8427593611152544 2.3076027908689647 0.0210212391502906 1.0 0.1391234716413822 3 Q9NWM8 1 +Increased cerebral lipofuscin 0.9036496350364808 2.306044939357846 0.0211081214066237 1.0 0.1394997611026657 5 O14773,O75503,P07602,P50897 4 +Generalized myoclonic seizure 0.4338680221910945 2.3001393957918936 0.0214403239695102 1.0 0.1404961144743929 45 P07602,P03886,P16278,Q9Y619,Q9NZJ7,Q13510,Q96N66,P04062 8 +Low back pain 0.7584597432905508 2.295886752703502 0.0216823573857394 1.0 0.1418820174847118 2 Q8WVX9 1 +Poor eye contact 0.4468989759769612 2.2910029026315497 0.0219632457834151 1.0 0.1430374784404777 42 Q9Y6M9,Q9NPL8,Q86Y39,P03886,Q06787,Q96CU9,O43676,Q15907,Q9UHX1,Q9P0J0 10 +Increased bone mineral density 0.5397864900709258 2.286283513830023 0.0222376777243553 1.0 0.1436943681604381 27 Q13126,Q15392,P54802,Q9Y4P3,Q14108,Q14739,P04062,Q15043 8 +Recurrent pancreatitis 0.8367083102619246 2.2805773427584572 0.0225734692863852 1.0 0.144515089679513 3 P00403 1 +Ventricular preexcitation 0.8749485399356238 2.2802670296579937 0.022591855990111 1.0 0.144515089679513 6 P10253,P03886,P00403,P13473 4 +Hepatomegaly 0.3356433372691035 2.2790088473130554 0.0226665393817984 1.0 0.144515089679513 179 P61916,P51798,Q96CU9,Q16134,O43676,Q01844,Q9H0U3,P08236,P04062,O75306,P23786,Q10713,P07602,Q86Y39,P16278,Q9Y619,Q9UJW0,Q9NWS8,P10253,Q96EY8,P09601,Q14108,Q9NVI7,Q15067,Q9Y6M9,Q9NPL8,O75648,Q6NUQ1,P03886,P00374,P15586,Q9NZJ7,Q99519,O75845,P54802,O43772,Q16625,Q14739,Q96RL7,Q6PGP7,Q14376,Q15904,Q9BT22,O15118,Q96HY6,Q96A33,Q13510,P35610 48 +Generalized osteosclerosis 0.836356101201967 2.2790019278414 0.0226669507014134 1.0 0.144515089679513 3 Q15392 1 +Decreased light and dark adapted electroretinogram amplitude 0.8343638025837243 2.2700855774183046 0.0232023912308121 1.0 0.1470645425079852 3 P50897 1 +Abducens palsy 0.8333315703819899 2.265462649831177 0.0234843035454144 1.0 0.1475273114235256 3 P07602 1 +Ascites 0.5190689508739013 2.265087296779666 0.0235073230152638 1.0 0.1475273114235256 29 P61916,Q99519,O15118,P08236,Q01844,Q13510,Q14108,Q14739,P04062 9 +Emg neuropathic changes 0.5697536137599547 2.263878408044667 0.0235815943015103 1.0 0.1475273114235256 23 O14773,P07602,Q8TB36,Q96RL7,Q9NZJ7,O43681,P22626,Q13510,Q9NR77,O60313 10 +Fractures of the long bones 0.8328131759282276 2.2631401417370007 0.0236270517291754 1.0 0.1475273114235256 3 Q13126 1 +Thin skin 0.527839911134055 2.261751880052006 0.0237127374042072 1.0 0.1475273114235256 28 O75844,Q6ZXV5,Q06787,Q9Y619,Q96L58,Q13126,Q96PU5 7 +Angiokeratoma 0.832376320509665 2.2611825082084502 0.0237479578053334 1.0 0.1475273114235256 3 P16278 1 +No social interaction 0.7508751458576277 2.2585383798459344 0.023912114590608 1.0 0.1475273114235256 2 Q15067 1 +Inability to walk 0.3708532761908956 2.2583996891743703 0.0239207520935489 1.0 0.1475273114235256 94 P61978,Q8TB36,Q96CU9,Q99720,O14949,O15269,O15270,Q96N66,Q9NVI7,Q8N201,Q15043,O43292,Q99519,P12235,Q96RL7,O75503,P35637,Q13510,Q9NR77 19 +Ascending tubular aorta aneurysm 0.8923616855128668 2.2583883563408627 0.0239214580095685 1.0 0.1475273114235256 5 O75844,Q96L58,Q06787 3 +Poor head control 0.3916943901532673 2.253326245212072 0.024238586120209 1.0 0.1487615206268046 74 P51970,P17900,Q10713,Q9NPL8,P07602,Q9Y6M9,Q86Y39,P03886,Q96CU9,P00374,Q9NZJ7,P06865,P13073,Q9NWM8,O43676,Q9P0J0 16 +Hydrocephalus 0.3711458771670074 2.252535839807127 0.0242884304924886 1.0 0.1488120757197373 89 P51798,Q9UBN7,O95202,Q15392,P21964,P08236,P04062,P23786,Q10713,Q12768,P53701,Q15427,Q6NUK1,O15360,Q99519,Q96L58,O96028,Q8TAA9,Q00839,P16435,P48651,Q9UBM7,Q8NAT1,Q9H490,Q14738 25 +Abnormality of lower limb joint 0.3349755297256 2.252180248775934 0.0243108836571848 1.0 0.1488120757197373 178 Q7LGA3,O95202,P21964,P08236,Q86XL3,O75844,P23786,P49902,O95831,P07602,P37268,P16278,Q9Y619,Q9Y487,Q15427,Q9Y4P3,Q15043,P42858,Q6NUQ1,Q9NZJ7,Q96L58,Q13535,Q96PU5,O96028,O75718,Q96AY3,P16435,P48651,Q6ZXV5,Q9UHX1,Q9Y584,Q96HY6,Q96A33,Q13510,Q9NR77,Q14738 36 +Pulmonary fibrosis 0.5821769821381471 2.247784214946715 0.0245899528928568 1.0 0.1493610137199211 21 Q8IZA0,P09601,P04062 3 +Aplastic clavicle 0.8291815757121817 2.246854122544246 0.0246493515137582 1.0 0.1493610137199211 3 Q9Y619 1 +Heparan sulfate excretion in urine 0.9104341508953367 2.24313998577507 0.0248877888773606 1.0 0.1499723309004119 4 P15586,P54802 2 +Foam cells 0.8178987347118823 2.242023267835562 0.0249598685398861 1.0 0.150211851342372 7 P16278,O15118,Q99519,O75845,Q13510 5 +Proportionate short stature 0.4823470855794294 2.2400781293413536 0.0250858511173646 1.0 0.1503856313435819 35 P10619,P53701,P48651,P16278,Q9Y619,Q96L58,Q13535,Q15392,Q14739 9 +Abnormality of the curvature of the vertebral column 0.2895865583649808 2.2366438926771735 0.025309623764274 1.0 0.1515315876402283 343 Q7LGA3,O75874,P61978,Q8TB36,P48735,Q96CU9,P51571,O95202,Q6DKJ4,Q99720,P98175,P21964,Q9BQT8,P04062,P08236,O75844,Q2TAA5,Q32P28,O95831,Q10713,Q99567,P16278,Q9Y487,P50402,Q9NWM8,O15228,Q15427,Q9Y4P3,Q9NVI7,Q14108,Q8N201,Q15043,P04350,P42858,O75648,P55795,Q06787,O15360,Q9UL01,Q99519,Q96L58,Q13535,Q96PU5,O96028,P22626,O75718,Q14739,Q9UG56,Q8TAA9,Q96AY3,P16435,P48651,Q6ZXV5,P35637,P51648,Q9BT22,P01889,Q9UHX1,Q96HY6,Q96A33,Q13510,Q9NR77,O60568,Q14738 64 +Myoclonus 0.3662450665087231 2.2315502060656893 0.0256447057654931 1.0 0.1529464736668565 105 Q96CU9,Q9UBX3,Q13315,P50897,P00403,P04062,O14773,Q10713,P07602,Q9NWS8,Q14108,P42858,Q9NPL8,P03886,P00374,P05067,Q9NZJ7,Q99519,P13073,O75845,P23378,O75503,P27544,Q13510 24 +Widely patent fontanelles and sutures 0.9067913322797172 2.2281506677920224 0.0258704694874043 1.0 0.1538978248892197 4 O75844 1 +Abnormality of the gingiva 0.4261404539503414 2.2221113341695813 0.0262757824937487 1.0 0.1559096876959854 47 P16278,Q14108,Q99519,Q14739,Q6DKJ4,Q15392,P08236,Q9Y4P3,P04062 9 +Absent nipple 0.7432905484247434 2.2210440032129832 0.0263479811578684 1.0 0.1561386740554293 2 Q6NUK1 1 +Agenesis of cerebellar vermis 0.7429988331388375 2.2195990067445055 0.0264459997673291 1.0 0.15614544909227 2 Q10713 1 +Neonatal breathing dysregulation 0.7429988331388375 2.2195990067445055 0.0264459997673291 1.0 0.15614544909227 2 Q10713 1 +Abnormal atrioventricular valve morphology 0.4645540053606214 2.217527518681028 0.0265870647102599 1.0 0.1566198610937541 38 O75844,P55795,P53701,Q06787,Q9UL01,Q96L58,Q9Y4P3,P21964,P04062 9 +Amyloidosis 0.8214098931878728 2.2119094440381923 0.0269729225847834 1.0 0.1566198610937541 3 Q9Y287 1 +Abnormality of the distal phalanges of the toes 0.9027712093746728 2.2115820484932347 0.0269955569220017 1.0 0.1566198610937541 4 O75844 1 +Mixed demyelinating and axonal polyneuropathy 0.901399665836326 2.205922923276576 0.0273893968902716 1.0 0.1581916381405957 4 P00403 1 +Hepatic failure 0.422481708514616 2.2043124498138233 0.0275023779904883 1.0 0.1585310771015 51 P23786,O75648,Q10713,Q6NUQ1,P03886,P08574,Q9Y619,O15460,O15118,P01889,O75845,P22830,O43772,Q13510,P04062 15 +Avascular necrosis 0.561553381625325 2.203142924643731 0.0275846765920269 1.0 0.1588084354975923 23 O75844,Q9Y619,Q9NZ08,Q14108,P04062 5 +Abnormal femoral neck head morphology 0.4233825315500358 2.2012681811704713 0.0277170440301035 1.0 0.1593730031730954 49 Q7LGA3,O75844,Q96AY3,Q96A33,P16278,Q9Y619,Q9Y487,Q96L58,Q96HY6,O75718,O60568,Q14739,O95831 13 +Wide cranial sutures 0.8089080621841129 2.1999980832634636 0.0278070310181803 1.0 0.1595073341617962 7 O75844,O75718 2 +Progressive psychomotor deterioration 0.7455117351910164 2.199005981279044 0.0278774970037105 1.0 0.15970265237884 9 Q10713,P07602,P16278,Q9NZJ7,O43681 5 +Skeletal muscle hypertrophy 0.4239844528355281 2.197995003451852 0.027949462003757 1.0 0.1597229152201997 47 Q7LGA3,P61978,Q10713,P16278,Q8NAT1,Q9Y4P3,P10253,Q96A33,Q9NR77 9 +Posteriorly rotated ears 0.3613481993794745 2.1976444669906643 0.0279744518002176 1.0 0.1597229152201997 112 Q7LGA3,O95202,Q15392,P98175,P04062,P23786,Q10713,P37268,Q99567,Q9Y619,Q15427,Q9Y4P3,P07437,P42892,Q9UL01,Q96L58,O96028,P16435,Q8NAT1,Q4J6C6,Q9UHX1 21 +Optic neuropathy 0.5681051928555318 2.1975082234206154 0.0279841698211886 1.0 0.1597229152201997 22 Q9Y6M9,Q9NPL8,Q86Y39,P03886,Q96CU9,O43676,Q9P0J0 7 +Progressive sensorineural hearing impairment 0.7294540753948554 2.192312219181514 0.0283569700497028 1.0 0.161059269988899 10 P03886,O60313,P00403 3 +Abnormal cardiac ventricular function 0.5871190208676637 2.189041278228616 0.0285938399408702 1.0 0.1618111819309175 19 O75844,P03886,P00403,P12235 4 +Abnormal systemic arterial morphology 0.3448932472549679 2.1852480317908993 0.0288706654996353 1.0 0.1627237537234539 152 Q7LGA3,P61978,O14678,P61916,P38435,O15460,P06865,Q6DKJ4,P21964,P04062,O75844,O43683,P07602,P53701,P16278,Q9NWM8,Q9Y4P3,P10253,Q6NUK1,P42858,P17900,O75648,P03886,Q06787,O15360,P05067,Q9NZJ7,Q99519,Q96L58,Q96PU5,O75845,P10619,Q6ZXV5,O15118,P01889,Q96PZ0,Q96MF7,Q9UHX1,Q13510,O60568 40 +Ambiguous genitalia male 0.8154762830776009 2.185145119436334 0.0288782079288822 1.0 0.1627237537234539 3 Q15392 1 +Atlantoaxial abnormality 0.8943315010479331 2.1767073669996577 0.0295024082877033 1.0 0.1657414617952475 4 Q9NWM8,Q9UL01 2 +Bowing of the legs 0.4178134931403999 2.1761902871619365 0.0295410348903997 1.0 0.1657580291072428 54 Q7LGA3,Q32P28,P16435,P16278,Q9Y619,Q96L58,Q13126,Q9Y4P3,O75718,Q9NR77,P08236 11 +Bilateral sensorineural hearing impairment 0.5259769229033555 2.1750743636426746 0.029624544227141 1.0 0.1657596033857076 27 P07602,P38159,P03886,P35637,Q9NZJ7,O43681,P00403,Q15067 8 +Thickened ribs 0.893921993831202 2.175012066818353 0.0296292121426042 1.0 0.1657596033857076 4 P16278,P54802 2 +Gastric ulcer 0.8126538791310748 2.1723887725758475 0.0298263511516498 1.0 0.1663289474413631 3 P04062 1 +Calcinosis 0.8719585584244505 2.171651149576093 0.0298819858028198 1.0 0.1663289474413631 5 O75844 1 +Abnormal retinal morphology 0.3201956828478889 2.171345672394247 0.0299050522964419 1.0 0.1663289474413631 231 Q7LGA3,P38435,Q96CU9,Q7KZN9,Q13045,P06865,O95202,P50897,P21964,P00403,P04062,Q9P0J0,O75306,O14773,Q10713,Q12768,P07602,P53701,P16278,Q9Y619,Q9Y487,Q9Y4P3,Q9NZ08,P07437,Q9Y287,Q8N201,Q15067,P42858,P17900,O75648,P55011,P03886,Q9NZJ7,Q9UL01,Q99519,O96028,Q6P4Q7,Q9UG56,P10619,O76024,O60762,O14936,O75503,P51648,P01889,Q96PZ0,Q8NAT1,Q5XKP0,P04439,Q9UHX1,Q96MF7,P51812,Q13510,O60313 54 +Monochromacy 0.7327887981330283 2.168889259870833 0.0300910923351225 1.0 0.1670289306917315 2 Q6P4Q7 1 +Respiratory arrest 0.7394682448194972 2.167856191102282 0.0301696299524978 1.0 0.1672650367056145 9 Q96L58,P23786,P13473 3 +Progressive external ophthalmoplegia 0.7388675549195303 2.164754804648541 0.0304064676073845 1.0 0.1683771734253975 9 P12235,P03886,P00403 3 +Abnormal csf metabolite level 0.4130370193230974 2.162691959465848 0.0305648799391842 1.0 0.1690528954731546 59 P51970,Q9Y6M9,Q9NPL8,Q86Y39,P03886,Q96CU9,P14854,P13073,O43676,Q9NWS8,P00403,Q9P0J0,O95831 13 +Abnormality of visual evoked potentials 0.5631795298331023 2.1615340619017775 0.0306541087262097 1.0 0.1693376234264841 22 P07602,O75503,P51798,Q9NZJ7,Q92974,P14854,O60313,Q15067 8 +Abnormality of the larynx 0.4179400070927553 2.1597793820603153 0.0307897524914022 1.0 0.169413293804842 52 P07602,P16435,Q15165,P35637,Q9NZJ7,Q15427,Q9UHX1,Q13510,P21964,Q14739,Q92804 11 +Micromelia 0.5467703655430631 2.1486165347562927 0.0316648098748733 1.0 0.1720184760557059 24 O75874,P48735,Q9UHX1,Q15392,O75718 5 +Cough 0.5140948517634482 2.1482555483009365 0.0316934600739742 1.0 0.1720184760557059 28 O15269,O15270,P01889,Q9NR77,P35610,P04062 6 +Abnormality of the radioulnar joints 0.8063316950501542 2.1437551284703877 0.0320525124244166 1.0 0.1727428892031768 3 P16435 1 +Radioulnar dislocation 0.8063316950501542 2.1437551284703877 0.0320525124244166 1.0 0.1727428892031768 3 P16435 1 +Postural tremor 0.5967522723581493 2.1413973331995284 0.0322420098199818 1.0 0.1727755220572497 18 O75306,O14773,P03886,Q06787,P35637,O75569,Q9NR77,Q14108 8 +Abnormality of acid base homeostasis 0.3266812119717046 2.13999979645011 0.0323547831942421 1.0 0.1730666617797664 182 P51970,O14678,P11177,Q9NP80,P48735,Q96CU9,Q9UBX3,Q7KZN9,Q70HW3,P53985,O43676,O14949,P00403,Q9P0J0,O95831,O75306,P23786,Q99797,Q10713,Q86Y39,P08574,Q13277,Q9Y619,Q9BWD1,Q9NWS8,Q96EY8,Q9NVI7,Q9Y6M9,Q9NPL8,O75648,P03886,P13073,Q5JRX3,Q00325,P12235,Q9BW92,Q9Y2Z2,Q6P4A7,P14854,P01889,Q4J6C6,Q9Y584,P35610 43 +Exostoses 0.8853214793903682 2.1393406218832114 0.0324080920681009 1.0 0.1730666617797664 4 O75874 1 +Mania 0.6583173042571567 2.1370157089518576 0.0325967139500811 1.0 0.17387409071421 14 P12235,P03886,P00403,P16615 4 +Muscle stiffness 0.5794538253042214 2.1359320010935896 0.0326849567581408 1.0 0.1741448498833973 19 P53985,P23786,P07602,Q15392 4 +Saccadic oscillation 0.804133098488435 2.133778338020602 0.0328609299146664 1.0 0.1746817853358587 3 P04062 1 +Opsoclonus 0.804133098488435 2.133778338020602 0.0328609299146664 1.0 0.1746817853358587 3 P04062 1 +Peripheral opacification of the cornea 0.7254959159859982 2.1325084142217103 0.0329650735162463 1.0 0.1750351217788348 2 P54886 1 +Hypokinesia 0.6703704385918283 2.1221771398665505 0.0338228654769381 1.0 0.1787725062637708 13 O95831,Q99567,P13473,P12235,P04062,Q2TAA5 6 +Ankylosis 0.8594719237966677 2.118192974307986 0.0341587279583328 1.0 0.1801378548177235 5 O75844,P16435 2 +Abnormal bleeding 0.3567189412051421 2.1161730822540035 0.034330089671152 1.0 0.1804230788351812 111 P38435,P21964,P04062,O75844,P23786,Q4KMQ2,Q9Y487,Q9NWM8,Q9NZ08,Q14108,P05067,Q9UL01,Q99519,Q96L58,Q96PU5,Q16625,Q14739,Q6ZXV5,P01889,Q13126,P11117,Q9UHX1,O60568 23 +Abnormal metabolic brain imaging by mrs 0.5929341534556248 2.115730723973038 0.0343677159454811 1.0 0.1804230788351812 18 P07602,P03886,Q9NZJ7,P35610,P00403 5 +Increased c peptide level 0.721995332555432 2.114998748431746 0.0344300539859707 1.0 0.1804230788351812 2 Q16836 1 +Abnormal morphology of the musculature of the neck 0.6539638243343489 2.111088735238648 0.0347646854953034 1.0 0.1804230788351812 14 P35637,Q96L58,O75569,Q99720,Q14738 5 +Abnormality of the spleen 0.3448324669824916 2.1108460123589476 0.0347855497503317 1.0 0.1804230788351812 137 P61916,P36551,P51798,Q13315,O95202,Q15392,Q9H0U3,P21964,P08236,P04062,Q96KP1,Q96J02,Q10713,P07602,P11166,P16278,P28288,P10253,Q9NZ08,Q14108,Q6NUQ1,P15586,Q9NZJ7,Q99519,O75845,O96028,P54802,Q16625,Q14739,P10619,Q96RL7,O60762,O14936,Q14376,Q15904,Q5HYI8,Q6PGP7,Q9BT22,O15118,P01889,Q96HY6,Q96A33,Q13510 43 +Abnormal pupillary light reflex 0.8784458449135278 2.110732338718045 0.0347953247172454 1.0 0.1804230788351812 4 Q9NR77,P07602 2 +Slow pupillary light response 0.8784458449135275 2.110732338718045 0.0347953247172454 1.0 0.1804230788351812 4 Q9NR77,P07602 2 +Pathologic fracture 0.5918653694685923 2.108534747428187 0.0349847604204658 1.0 0.1810013328657953 18 O15269,O15270,Q96L58,Q13126,P22626,Q14108,O60568,P04062 8 +Pedal edema 0.7890517369251302 2.1065531997561178 0.0351563270807944 1.0 0.181686646960368 7 P04062 1 +Hyperconvex nail 0.7272695527050003 2.1046883436764854 0.0353184457977822 1.0 0.1823216657516623 9 P42892,P48651,Q9Y619,O96028,O95202 5 +Vitiligo 0.7410074471312712 2.103982805798019 0.0353799468985307 1.0 0.1824364409440331 8 P00403 1 +Action tremor 0.4080987061875518 2.1028449449940276 0.0354793257329257 1.0 0.1827460613693716 59 O75306,O14773,P07602,Q96RL7,P03886,Q06787,P35637,Q14108,Q9NZJ7,Q5JRX3,O75569,Q99720,Q9NR77,Q9Y287 14 +Short palpebral fissure 0.4761515663085173 2.1013379274570356 0.0356113126234345 1.0 0.1832227668310928 33 O75844,Q6NUK1,P55795,O15360,Q9Y619,Q9UHX1,P07437,P98175 8 +Cystinuria 0.719078179696599 2.1003842819144536 0.0356950505617206 1.0 0.1833777010856806 2 Q4J6C6 1 +Stillbirth 0.6815647518377913 2.0966370705206643 0.0360257150807366 1.0 0.1845374556395835 12 O75844,Q14739,P04062 3 +Abnormal epiphyseal ossification 0.6053563505885252 2.092302980862508 0.0364114212356729 1.0 0.1855222640224978 17 Q9UG56,P38435,Q9UBM7,Q99519,Q96L58,Q96HY6,P08236,Q14739 8 +Mandibular aplasia 0.8738662422203336 2.0916329190624148 0.0364713654102719 1.0 0.1855925122630049 4 Q9Y619 1 +Toe walking 0.5316487919163099 2.0910800563892846 0.0365208881697303 1.0 0.1856411886614519 25 Q8TD16,P40939,Q8WXH0,P07602,Q9NP80,P15289,Q9H9S5,P35637,Q9NZJ7,P50402,Q9BTV4,O43681,Q8ND04,Q99720,P54886,O95831 16 +Slender long bone 0.6354553779919258 2.088730775128876 0.0367319649198789 1.0 0.1865100645002815 15 Q32P28,P37268,Q9Y619,Q9Y487,Q96L58,Q96MF7,Q9H490 7 +Abnormal tongue physiology 0.565227467371045 2.0798152449476177 0.0375424822574124 1.0 0.1892670978601518 20 P04350,P51114,Q9NWS8,P10253,Q13510,Q9BQT8,O95831 7 +Stroke like episode 0.8490415554277244 2.0733227341403633 0.0381422543207454 1.0 0.1911248954170854 5 P03886,P51970,P00403 3 +Hemiparesis 0.570318753389949 2.07228416147228 0.0382389486099457 1.0 0.1911248954170854 19 P42345,Q9NP80,P03886,P01889,Q9NZ08,P00403 6 +Titubation 0.7068453303306214 2.07208098734445 0.0382578890955422 1.0 0.1911248954170854 10 Q99720,P35637,Q5JRX3 3 +Abnormality of the extraocular muscles 0.7132438739790012 2.0710927870036953 0.0383501257971912 1.0 0.1913798973724493 2 P43243 1 +Astrocytoma 0.7338857644372696 2.067851412514886 0.0386539974575395 1.0 0.1926646622351821 8 O75874 1 +Episodic vomiting 0.6754578921979735 2.062135482312906 0.0391948390603473 1.0 0.1949670474029699 12 Q9NP80,P03886,Q9Y619,P00403,Q2TAA5 5 +Frontotemporal dementia 0.7186853863369949 2.060005496969554 0.0393980153161135 1.0 0.1957681060520465 9 P35637,P05067,P31483 3 +Left ventricular systolic dysfunction 0.824670994923454 2.05863239599937 0.0395294668977279 1.0 0.1960020311705913 6 O75844 1 +Abnormality of the parathyroid morphology 0.7783637602535312 2.0559008072258877 0.0397920783059955 1.0 0.1970938121638114 7 O75874 1 +Bilateral tonic clonic seizure with focal onset 0.7843594981032673 2.0436099289888117 0.040992097611495 1.0 0.2015441082095231 3 Q9NZJ7,P07602 2 +Bruising susceptibility 0.4737140804703675 2.042667251416523 0.0410853887777877 1.0 0.2015441082095231 32 P38435,O15360,Q9UL01,Q96L58,Q13126,Q9NWM8,Q14108,O60568,P04062 9 +Cachexia 0.5658534861004505 2.0410341249564925 0.0412474352911274 1.0 0.2015441082095231 19 P07602,P35637,Q9NZJ7,Q01844,Q99720,P04062 6 +Amyotrophic lateral sclerosis 0.6276593851696314 2.040681985635904 0.041282447077461 1.0 0.2015441082095231 15 P31483,Q15165,P35637,Q99720,Q92804 5 +Kyphosis 0.3359094573754577 2.03954968288333 0.041395198002192 1.0 0.2015441082095231 155 Q7LGA3,Q8TB36,O95202,Q6DKJ4,P08236,P04062,O95831,O75844,Q32P28,Q99567,P16278,Q9Y487,P50402,Q9NWM8,Q9Y4P3,Q14108,P04350,P42858,O75648,Q9UL01,Q99519,Q96L58,O96028,Q14739,Q96AY3,P48651,P51648,Q9BT22,P01889,Q9UHX1,Q9NR77 31 +Abnormality of corneal stroma 0.6419830643984024 2.039406845322476 0.0414094397964837 1.0 0.2015441082095231 14 P10619,P16278,Q16625,Q13510,P04062 5 +Abnormality of lysosomal metabolism 0.84117911231663 2.039371439812015 0.0414129705880335 1.0 0.2015441082095231 5 Q9NZJ7,Q13510,P07602 3 +Abnormality of the lymphatic system 0.3288816228690805 2.036140652310773 0.0417362336295132 1.0 0.2019859806694986 170 O75874,P61916,P48735,P51798,O15460,Q13315,O95202,Q01844,Q15392,P21964,P08236,P04062,Q10713,P07602,P16278,P10253,Q9NZ08,Q14108,Q6NUQ1,P15586,Q9NZJ7,Q99519,O75845,O96028,P54802,Q16625,Q14739,P10619,Q96RL7,Q6PGP7,Q14376,Q15904,Q5HYI8,Q9BT22,O15118,P01889,Q96HY6,Q96A33,Q13510 39 +Oromandibular dystonia 0.8189438506866303 2.0330787689007996 0.0420445656021022 1.0 0.2027638826168176 6 Q99720,P35637,Q15043 3 +Lower limb spasticity 0.3565526970931063 2.0317810544169057 0.0421758259974547 1.0 0.2028456393210918 87 Q96CU9,Q7KZN9,Q8WVX9,Q8TAF3,Q99720,Q9P0J0,P04062,P49902,O95831,O75306,Q12768,P07602,P11166,Q5T160,Q9Y619,O75477,P21912,P54886,Q5TBB1,Q15041,Q99519,Q9NZJ7,Q6DKK2,Q04446,P35637,Q5XKP0,O60313 27 +Subcutaneous hemorrhage 0.4097516376927986 2.0309465283613735 0.0422604191460225 1.0 0.2030423033634132 44 P38435,O15360,Q99519,Q9UL01,Q96L58,Q13126,Q9NWM8,Q16625,P21964,Q14108,O60568,P04062 12 +Goiter 0.7719581895573744 2.0254267290472123 0.0428235651249027 1.0 0.2046895921505123 7 O75874,P48735 2 +Abnormal pupillary function 0.7714804662311804 2.023150516476105 0.0430576316311384 1.0 0.2055968721051069 7 Q9NR77,P07602 2 +Thin ribs 0.6389793348933905 2.02135998311539 0.0432425139916581 1.0 0.2060561230823011 14 O75844,Q32P28 2 +Progressive spastic quadriplegia 0.7111531309482101 2.02064254898978 0.0433167809975645 1.0 0.2061985292158656 9 Q9NZJ7,P17900,P07602 3 +Focal t2 hyperintense brainstem lesion 0.5627117421199577 2.0189927277806525 0.0434879753634094 1.0 0.2066081195255558 19 Q9Y6M9,Q9NPL8,Q86Y39,P03886,Q96CU9,O43676 6 +Abnormality of long bone morphology 0.3187038748015679 2.018956267240332 0.0434917651519572 1.0 0.2066081195255558 185 Q7LGA3,O75874,P38435,P48735,P51798,O95202,Q6DKJ4,P98175,P08236,O95831,O75844,Q32P28,Q15022,P37268,P16278,Q9Y619,Q9Y487,O15228,Q15427,Q9Y4P3,P42858,O75648,P55011,Q6NUQ1,O15360,Q99519,Q96L58,Q13535,O96028,P22626,O75718,Q14739,Q9UG56,Q96HY6,Q96AY3,P16435,P48651,O14936,Q9Y366,Q9UBM7,Q96PZ0,Q13126,Q9UHX1,P51812,Q96MF7,Q9NR77,O60568 47 +Severe short stature 0.5297086651752461 2.0178668329686067 0.043605132116433 1.0 0.2069350805035217 24 P10619,P53701,P48651,P16278,Q9Y619,Q96L58,Q15392 7 +Ectropion of lower eyelids 0.7018669778296398 2.013737135173802 0.0440371389967859 1.0 0.2083467899990504 2 Q99496 1 +Abnormal macrophage morphology 0.8143084274117699 2.012351440838894 0.0441829034313325 1.0 0.2086115542093202 6 Q13510,P16278,O15118,Q99519 4 +Personality changes 0.607447648342381 2.0068771948285553 0.0447627406567818 1.0 0.2102807816899985 16 P42858,Q96RL7,P31483,P03886,P00403,P04062 6 +Mitochondrial inheritance 0.8520955879765895 2.0003577309279597 0.0454616492353834 1.0 0.2124899231118563 4 P03886,P00403 2 +Polar cataract 0.8519450949246516 1.999724054324631 0.0455300692673235 1.0 0.2125437572339144 4 Q7LGA3,Q9Y287 2 +Thin nail 0.6989498249708258 1.998980676457714 0.0456104446754654 1.0 0.2125437572339144 2 Q15022 1 +Disproportionate short limb short stature 0.5270824581187951 1.9976026807439036 0.0457597523951278 1.0 0.2127121067817595 24 Q7LGA3,P42345,Q32P28,Q9Y366,Q9UBM7,O15228,Q6DKJ4,Q15392,O75718,Q96MF7,Q14739 11 +Arthralgia 0.4522053654857967 1.9970609247857372 0.0458185650562599 1.0 0.2127121067817595 36 Q96HY6,Q9UL01,P01889,P06280,Q9Y4P3,Q15800,Q9NZ08,Q13510 8 +Muscle hypertrophy of the lower extremities 0.706484136512066 1.9961706623764832 0.045915349637174 1.0 0.2127121067817595 9 Q8NAT1 1 +Morphological abnormality of the pyramidal tract 0.5534933671294817 1.9961008126196085 0.045922950610526 1.0 0.2127121067817595 20 Q9H9P8,Q12768,P11177,P35637,Q9Y619,Q13045,O75569,Q9Y4P3,O95831 9 +High frequency sensorineural hearing impairment 0.8311014040126735 1.995695668922804 0.0459670588051843 1.0 0.2127121067817595 5 O75844,Q9NWM8 2 +Acantholysis 0.8508666978804584 1.9951822005152064 0.0460230116295035 1.0 0.2127591164484311 4 P16615 1 +Abnormality of the metacarpal bones 0.4364751327505562 1.993858291041129 0.0461675431647214 1.0 0.2131825191417989 39 Q6NUK1,Q32P28,P16435,P48651,P16278,P51798,Q9Y366,Q9UBM7,Q96L58,O96028,O95202,P08236,Q14739 13 +Epispadias 0.8493252861849735 1.9886869973088717 0.0467357620774171 1.0 0.2149697128003287 4 Q9Y619,P53701 2 +Decreased number of peripheral myelinated nerve fibers 0.5894445559160053 1.9878626506476385 0.0468268824574631 1.0 0.2149697128003287 17 O15269,Q9NR77,Q96RL7 3 +Abnormal larynx morphology 0.4597256784693055 1.9869585892046704 0.0469269860512537 1.0 0.2149697128003287 34 P07602,P16435,Q9NZJ7,Q15427,Q9UHX1,Q13510,P21964,Q14739 8 +Vascular neoplasm 0.4509611608044501 1.985009019659467 0.0471434679984124 1.0 0.2149697128003287 36 Q7LGA3,P42345,O75874,P10619,Q12768,P16435,O60762,P48735,Q9UBM7,O96028,O95202,Q9UHX1,P21912 13 +Optic disc hypoplasia 0.7714406594578467 1.9842794022686168 0.0472247010874888 1.0 0.2149697128003287 3 Q00839 1 +Erlenmeyer flask deformity of the femurs 0.8479276123759235 1.9827941449706576 0.0473904283021937 1.0 0.2150155565351486 4 Q9NZJ7,P07602,P04062 3 +Neoplasm of the adrenal cortex 0.8276756899925022 1.9808088826584256 0.0476127103007741 1.0 0.2156029747148117 5 O75874 1 +Nasogastric tube feeding in infancy 0.6756383454679771 1.9803901168347664 0.0476597096309383 1.0 0.2156056581746247 11 Q9NZJ7,Q9UHX1,P61978,P07602 4 +Abnormality of the temporomandibular joint 0.8472327669024144 1.9798633707973377 0.0477188832755453 1.0 0.2156633576830578 4 O75844 1 +Impaired social interactions 0.4017237181603973 1.9780681377857297 0.0479210204229609 1.0 0.2159902260467348 53 Q9Y6M9,Q15067,Q86Y39,P03886,Q06787,Q96CU9,O43676,Q15907,Q9UHX1,Q9P0J0,Q2TAA5 11 +Barrel shaped chest 0.846376868186772 1.9762522215176197 0.0481262180007946 1.0 0.2166612488679185 4 Q32P28 1 +Proximal tubulopathy 0.5241554020946722 1.974974308604796 0.048271063615298 1.0 0.2168929995712523 24 O75306,Q9Y6M9,Q9NPL8,Q86Y39,P03886,Q96CU9,Q16134,O43676,P00403 9 +Orchitis 0.7688940764516908 1.9725457124794648 0.048547343302645 1.0 0.2175033336394302 3 P01889,Q9NZ08 2 +Pleuritis 0.7688940764516908 1.9725457124794648 0.048547343302645 1.0 0.2175033336394302 3 P01889,Q9NZ08 2 +Neuroinflammation 0.7688940764516908 1.9725457124794648 0.048547343302645 1.0 0.2175033336394302 3 P01889,Q9NZ08 2 +Motor neuron atrophy 0.5439523562010311 1.971991887558863 0.048610532615315 1.0 0.2175766228619975 21 P31483,Q13510,Q15165,P35637,P22626,Q99720,Q16637,Q92804 8 +Abnormal brainstem mri signal intensity 0.5306605708732787 1.9711487554833025 0.0487068633656073 1.0 0.217797966502995 23 Q9Y6M9,Q9NPL8,Q86Y39,P03886,Q96CU9,O43676,O95831 7 +Abnormality of skull ossification 0.6438934978430321 1.9676538539296264 0.0491078787731438 1.0 0.2189589297313111 13 O75844,O75718,Q32P28,P54802 4 +Spastic diplegia 0.5295603704550426 1.962795949716742 0.0496698886342898 1.0 0.2212524473584955 23 Q99720,P35637,P51648,P07602 4 +Schizophrenia 0.5290683403377036 1.959058452569124 0.0501059417294451 1.0 0.2223795021680021 23 Q9BQE5,O76024,P07602,Q9NZJ7,P16615,P21964,P04062 7 +Abnormality of the umbilical cord 0.7124137386898408 1.958169777183335 0.0502100942260512 1.0 0.2223795021680021 8 O75844,P16435 2 +Sclerocornea 0.6853723310779036 1.956610497509352 0.0503932798734834 1.0 0.2228075700969373 10 Q6NUK1,P53701,O96028,O95202,O75569 5 +Abnormal abdomen morphology 0.3107928661932947 1.9565307856216705 0.0504026595290316 1.0 0.2228075700969373 230 P61916,P51798,Q96CU9,Q13315,Q16134,O43676,Q15392,Q9H0U3,Q01844,P21964,P08236,Q9UGP8,P04062,O75306,P23786,O43683,Q10713,P07602,Q86Y39,P16278,Q9Y619,Q9UJW0,Q9NWS8,P10253,Q9NZ08,Q96EY8,P09601,Q14108,Q9NVI7,Q15067,Q9Y6M9,Q9NPL8,O75648,Q6NUQ1,P03886,P00374,P15586,Q9NZJ7,Q99519,O75845,P54802,O43772,Q16625,Q14739,P10619,Q96RL7,Q6PGP7,Q14376,Q15904,Q5HYI8,Q9BT22,O15118,P01889,Q96HY6,Q96A33,Q13510,P35610 57 +Neoplasm of the parathyroid gland 0.8016346054985548 1.9554786083365012 0.0505266058394733 1.0 0.2229312542546943 6 O75874 1 +Parathyroid adenoma 0.8016346054985548 1.9554786083365012 0.0505266058394733 1.0 0.2229312542546943 6 O75874 1 +Fluctuations in consciousness 0.7568194333369644 1.9530635518749904 0.050812065164739 1.0 0.2237101036582346 7 P00403,P04062 2 +Vocal cord paresis 0.7639334695068496 1.9496533704766073 0.0512174475775468 1.0 0.224176911044058 3 P43243,Q8TB36 2 +Aplasia hypoplasia involving bones of the thorax 0.4319931008098978 1.9481300195351892 0.0513994076448454 1.0 0.224176911044058 39 O75844,P16435,P48651,Q9Y619,Q96L58,Q13535,Q15427,Q9UHX1,P98175,Q14739 10 +Abnormal diaphysis morphology 0.36931365908291 1.9459575988248208 0.0516598331256934 1.0 0.2246518824660157 74 Q7LGA3,Q32P28,Q96AY3,P16435,P48651,P16278,Q9Y619,Q9Y487,Q96L58,Q13126,Q9Y4P3,O75718,Q9NR77,P08236,Q14739 15 +Elevated serum acid phosphatase 0.8389841676386618 1.945012494715748 0.0517734745178113 1.0 0.2248033295418237 4 Q9NZJ7,P07602 2 +Abnormal circulating arginine concentration 0.6881563593932394 1.9442079983172824 0.0518703736639056 1.0 0.2250137778174657 2 Q9UJS0 1 +Abnormal labia minora morphology 0.709268484708841 1.9420114853374983 0.0521357099017198 1.0 0.2256631607571132 8 Q9Y619 1 +Temperature instability 0.7090425337572842 1.9408498072297424 0.0522764976196392 1.0 0.2256631607571132 8 P07602,Q2TAA5 2 +Abnormal protein o linked glycosylation 0.7610453017988128 1.9363033964233036 0.0528305530680137 1.0 0.2266396579445909 3 Q8N511 1 +Lop ear 0.68611435239207 1.9338152263184012 0.053135850017461 1.0 0.2273196677542577 2 P78318 1 +Cold induced muscle cramps 0.7601121068897121 1.931986520530051 0.0533611696338525 1.0 0.2278639651827929 3 P23786 1 +Decreased activity of mitochondrial complex iv 0.5806895803690177 1.9299748242920107 0.0536099572221984 1.0 0.2285062947287466 17 Q70HW3,Q9Y2R0,Q9Y584 3 +Constitutional symptom 0.3049526905054107 1.928846707656017 0.0537498953901016 1.0 0.228683162987557 258 O75874,Q9NP80,P48735,Q15165,P51798,O15460,Q70HW3,Q13315,Q13423,P06280,Q01844,Q99720,P21964,Q9UGP8,P04062,O75844,P23786,O15269,O43572,Q12768,P07602,O15270,P50402,O43681,Q9Y4P3,Q9NZ08,O75477,Q14108,Q15043,P42892,P43243,Q99959,Q06787,Q9NZJ7,Q9UL01,O75569,P22626,Q15800,P12235,Q14566,O60313,Q8N1F7,P23378,Q14739,Q92804,Q8TAA9,Q12769,O14936,P35637,Q5HYI8,P14854,P01889,Q4J6C6,Q96HY6,Q13510,Q9NR77,P35610 57 +Bifid epiglottis 0.6843640606767807 1.9248995462942091 0.0542419266946927 1.0 0.2299342987441081 2 Q9P2L0 1 +Horizontal ribs 0.6843640606767807 1.9248995462942091 0.0542419266946927 1.0 0.2299342987441081 2 Q9P2L0 1 +Pituitary adenoma 0.665068843707755 1.9216521509017777 0.0546495418060672 1.0 0.231240228807822 11 O75874 1 +Abnormal intraocular pressure 0.7934374893639418 1.918540060478366 0.0550425675615451 1.0 0.2320578665072038 6 Q15043,Q9UL01 2 +Abnormal pharynx morphology 0.411838620483679 1.91704353898674 0.05523240059075 1.0 0.2326470835400044 42 Q13510,Q13277,P16278,O15460,P15586,Q13315,P01889,Q03519,P54802,Q9H0U3,Q03518,P08236 12 +Mucosal telangiectasiae 0.6913710810243644 1.9165866458966387 0.0552904658795445 1.0 0.2326807105764167 9 P10619,P06280,Q14739,Q8IZA0 4 +Intestinal hypoplasia 0.8321566828541003 1.9160841466918352 0.0553543858639429 1.0 0.2327388929627862 4 O75844 1 +Hyperglycemia 0.7478652291952357 1.9100414074158905 0.0561278821049253 1.0 0.2351398920283888 7 O75844 1 +Metatarsus valgus 0.7548876568426969 1.9077885214282624 0.0564185549439693 1.0 0.2357199696669796 3 O43505,Q8NAT1 2 +Macular degeneration 0.6058235241034557 1.9049747969742732 0.056783347303702 1.0 0.2361821231629362 15 P51648,P04439,P50897,P04062 4 +Cardiac conduction abnormality 0.4330387007831204 1.90402205270455 0.0569073121647605 1.0 0.2364860217508742 38 O75306,P23786,Q9HD47,P03886,Q99959,P50402,Q14BN4,P06280,O43772,Q9H490,P00403 11 +Muscle fiber atrophy 0.5344709473736302 1.9024980131149856 0.0571060783604631 1.0 0.2367446553956727 21 P23786,P61978,Q96RL7,P35637,P22626,Q99720 6 +Undetectable electroretinogram 0.8288280922832182 1.9019542928303763 0.0571771303206498 1.0 0.2367602027359529 4 P50897 1 +Contractures of the joints of the lower limbs 0.3943701310965324 1.8986667423167607 0.0576083069561872 1.0 0.2381974386595957 54 Q7LGA3,P23786,P49902,Q96AY3,P37268,P48651,P35637,Q14738,Q99720,O60313,Q8IZA0,Q86XL3 12 +Choanal stenosis 0.808822993377941 1.8985265119759591 0.0576267587286667 1.0 0.2381974386595957 5 P16435 1 +Memory impairment 0.4265798281271166 1.8926748130166908 0.0584011279035439 1.0 0.2401164957874911 39 P42858,P07602,P31483,P03886,P52701,Q06787,P05067,Q9NZJ7,Q8WVX9,P49770,P01889,Q9UJS0,O43681,Q9NZ08,P49327,P00403 16 +Progressive cerebellar ataxia 0.4317729822275182 1.8912580386251592 0.0585899071636075 1.0 0.2405055921370694 38 O75306,P42858,O14773,O76024,P35637,Q96CU9,Q9Y619,Q9Y487,Q9P0J0 9 +Abnormal full field electroretinogram 0.7868212648910216 1.8886387982519584 0.0589402444939066 1.0 0.2414782856425841 6 P50897 1 +Abnormal light and dark adapted electroretinogram 0.7868212648910216 1.8886387982519584 0.0589402444939066 1.0 0.2414782856425841 6 P50897 1 +Generalized muscle weakness 0.4489900404842121 1.885578033253508 0.0593518398510564 1.0 0.2429503506149851 34 Q9H845,P42858,Q92804,Q03154,P43243,Q9H9S5,Q15165,P35637,P12235,Q9UL01,P49792,P50995,P10253,P40939,P21912,O95831 16 +Retinopathy 0.4744244862573955 1.8832403919833487 0.0596677974056505 1.0 0.2434791010482752 29 Q9NZ08,P51648,Q99519,P01889,O96028,O95202,P07437 7 +Choking episodes 0.6761960326720958 1.8832015274875549 0.0596730621320864 1.0 0.2434791010482752 2 P42858 1 +Staring gaze 0.6761960326720958 1.8832015274875549 0.0596730621320864 1.0 0.2434791010482752 2 P42858 1 +Incoordination 0.3719097079542875 1.883071814866605 0.0596906362664626 1.0 0.2434791010482752 71 O14773,Q10713,P07602,P31483,O75503,Q9Y619,Q6DKK2,P12235,Q99707,Q13510,Q9NR77,P04062,Q15067 13 +Distal peripheral sensory neuropathy 0.8051366208037163 1.8823683690074884 0.0597860175282463 1.0 0.243654243365116 5 P00403 1 +Abnormal astrocyte morphology 0.6287564404021276 1.8783384267688708 0.060334882926242 1.0 0.2456756056751274 13 P42345,O75874,P48735 3 +Generalized dystonia 0.7482657083640009 1.8770450826576432 0.0605119152149242 1.0 0.2459690220755916 3 P04350 1 +Abnormal gastrointestinal motility 0.4737115846592841 1.8770384327115488 0.0605128265674561 1.0 0.2459690220755916 29 P61978,O76024,P03886,Q5HYI8,P35637,Q9UBM7,P06280,Q01844,P00403 9 +Abnormal tissue metabolite concentration 0.600896947740315 1.8741337723842584 0.0609119894873044 1.0 0.2469433709930336 15 P06865,P17900,P06280,P07602 4 +Disproportionate short trunk short stature 0.8220527898339482 1.873140334291969 0.0610490088972295 1.0 0.2472830822463194 4 P16278 1 +Abnormal circulating citrulline concentration 0.8206750452582636 1.8672724958933808 0.0618635442346724 1.0 0.2481839174225117 4 Q9Y619 1 +Tissue ischemia 0.5296387973530886 1.8669223498707728 0.0619124322627402 1.0 0.2481839174225117 21 O75844,P05067,P01889,P06280,Q9Y4P3,Q9NZ08 6 +Abnormal elasticity of skin 0.3861645735429757 1.86580839110775 0.0620681779287097 1.0 0.2484242764160142 63 O75844,Q6NUK1,Q15022,O96000,P48651,P38435,Q15904,Q9Y487,Q9UL01,Q96L58,Q13126,Q9NWM8,Q9UHX1,Q9Y4P3,P07437,P04062 16 +Ragged red muscle fibers 0.5409845834481293 1.8653709334090989 0.0621294286904239 1.0 0.2484242764160142 19 P03886,Q70HW3,Q9H2D1,P12235,P00403,O95831 6 +Abnormal femoral neck morphology 0.4238641606339486 1.8647633351589832 0.0622145846904236 1.0 0.2484242764160142 39 O75844,Q96AY3,Q96A33,P16278,Q9Y619,Q9Y487,Q96L58,Q96HY6,O75718 9 +Neurofibrillary tangles 0.7814268037883965 1.8642029012799692 0.0622932161051779 1.0 0.2484242764160142 6 Q9Y287,P05067,O15118 3 +Epidermoid cyst 0.6721120186697817 1.8622968603669092 0.0625612577907785 1.0 0.2487857156891251 2 O60716 1 +Acetabular dysplasia 0.6679442663897239 1.8620128190492604 0.0626012833425471 1.0 0.2487857156891251 10 P16278,P08236,Q9Y584 3 +Retinal detachment 0.5848800414238581 1.861898893256878 0.0626173430924541 1.0 0.2487857156891251 16 Q9H9S5,Q9UL01,Q13045,Q8NAT1,P04439,O43505,Q96MF7,P49327 8 +Chronic fatigue 0.6936913739809564 1.8616513640704997 0.0626522482234595 1.0 0.2487857156891251 8 Q9NZJ7,Q13423,P07602 3 +Vomiting 0.3441035820726323 1.8615598437137684 0.0626651579672838 1.0 0.2487857156891251 100 P61978,Q9NP80,Q96CU9,P51571,Q13423,P06280,Q16134,O43676,P00403,Q2TAA5,O75306,P23786,P07602,Q86Y39,Q13277,Q9Y619,Q96EY8,Q9Y6M9,Q9NPL8,O75648,P03886,Q9NZJ7,Q9Y584,O96000,Q14376,Q9UBM7,P11117,Q03154,Q16836,P35610 30 +Psychomotor deterioration 0.6808574735404898 1.8608972601175244 0.0627586867816734 1.0 0.2487857156891251 9 P06865,Q9Y487,P07602,P50897 4 +Nausea and vomiting 0.3284391111431965 1.8592753241890183 0.0629881227859667 1.0 0.2492793640455884 148 P61978,Q9NP80,Q15165,Q96CU9,P51571,Q13423,P06280,O43676,Q01844,P00403,Q2TAA5,O75306,P23786,P07602,Q86Y39,Q13277,Q9Y619,Q9Y4P3,Q9NZ08,Q96EY8,Q9Y6M9,Q9NPL8,O75648,P42892,P03886,Q9NZJ7,Q8IZA0,Q92804,Q14376,P35637,P01889,P11117,Q9Y584,P35610 34 +Retinal dysplasia 0.6932291330672855 1.859258376990925 0.0629905237601207 1.0 0.2492793640455884 8 Q8NAT1,Q10713,P53701 3 +Poor wound healing 0.7367173342679085 1.8562564212238168 0.0634170174486015 1.0 0.250004906630872 7 O15269,P04062 2 +Multiple enchondromatosis 0.7792791253324083 1.8544604535870144 0.0636733128623343 1.0 0.2507001792867842 6 O75874 1 +Cardiovascular calcification 0.6795123791195772 1.8537536918566797 0.0637744063565075 1.0 0.2508200998473224 9 P04062 1 +Psychosis 0.4455102414747875 1.852537855955508 0.0639486267751492 1.0 0.2511456635649563 34 O76024,Q96RL7,P61916,P36551,P03886,Q8WVX9,O15118,Q6DKK2,Q5JRX3,P51812,Q9Y287,P00403 12 +Cupped ear 0.6238788700086856 1.849413994076726 0.0643980562718666 1.0 0.252270969172928 13 Q15392 1 +Abnormality of the synovia 0.344438887257722 1.8481420103220212 0.0645818017873043 1.0 0.2527776336173681 89 O75844,Q6NUQ1,Q96AY3,P16435,Q96A33,P16278,Q9Y487,Q96L58,Q13535,O96028,O95202,Q9UHX1,Q9Y584,Q15427,O75718,P08236,Q14738 17 +Confusion 0.5380822764075346 1.8446970167121188 0.0650816250979902 1.0 0.2545195540448337 19 P40939,P18074,P11166,P36551,Q9Y619,P05067,P01889,Q9UJS0,Q16836,Q9NZ08,P49327 11 +Atrophic scars 0.6899427811214346 1.8422315982812645 0.0654412802816071 1.0 0.2554959564607955 8 Q9NWM8,Q9UL01 2 +Decerebrate rigidity 0.7956243553469258 1.840572838490922 0.0656841811337911 1.0 0.2562289719123373 5 Q9NZJ7,P16278,P07602 3 +Abnormal temper tantrums 0.6893816298269957 1.839321874184066 0.065867857557776 1.0 0.2567299213199894 8 Q06787,P04062 2 +Juvenile onset 0.4101421331241499 1.8363613208211491 0.0663042361178603 1.0 0.2579978902877545 41 O14773,P16278,P51798,O15118,P50402,P06280,P54802,Q9H0U3,Q14566,Q13510,Q9NR77 11 +Cytochrome c oxidase negative muscle fibers 0.6758619704676556 1.8343459380105456 0.0666026591385642 1.0 0.2585519457252921 9 P12235,Q9Y2R0,P14854 3 +Abnormal mitral valve physiology 0.3983363265542376 1.8342723455767924 0.0666135770626721 1.0 0.2585519457252921 43 O75844,P53701,Q9UL01,Q96L58,P01889,P06280,Q9Y4P3,Q9NZ08,P04062 9 +Contractures involving the joints of the feet 0.52507755405028 1.8332453166192184 0.0667660974739725 1.0 0.2589276200868752 21 P49902,O60313,Q8IZA0,Q14738 4 +Limb ataxia 0.5125400789459056 1.8328164425853548 0.0668298730828405 1.0 0.2589587909448514 23 O14773,Q10713,Q8IV08,Q9NR77,Q14108,P04062 6 +Sensory ataxia 0.7937276494645193 1.8322218009537523 0.0669183821004339 1.0 0.2590856693655136 5 P54802 1 +Abnormal thoracic spine morphology 0.4554008870018124 1.829800240010189 0.0672798149151159 1.0 0.2591779626581429 31 O75844,P51648,O75845,Q9UHX1,P08236,P04062,O95831 7 +Patchy changes of bone mineral density 0.7381093312424929 1.8297382176656043 0.0672890931901444 1.0 0.2591779626581429 3 Q13126 1 +Female external genitalia in individual with 46 xy karyotype 0.6656942823804013 1.829373382113346 0.0673436923315917 1.0 0.2591779626581429 2 P51809 1 +Hypoplasia of the vagina 0.6656942823804013 1.829373382113346 0.0673436923315917 1.0 0.2591779626581429 2 P51809 1 +Ovarian gonadoblastoma 0.6656942823804013 1.829373382113346 0.0673436923315917 1.0 0.2591779626581429 2 P51809 1 +Gonadoblastoma 0.6656942823804013 1.829373382113346 0.0673436923315917 1.0 0.2591779626581429 2 P51809 1 +Abnormal sex determination 0.6656942823804013 1.829373382113346 0.0673436923315917 1.0 0.2591779626581429 2 P51809 1 +Left ventricular hypertrophy 0.5053384021043982 1.8284533948586763 0.0674815341046206 1.0 0.2591779626581429 24 Q6NUK1,P10253,Q07021,P03886,Q9H9S5,P12235,P06280,Q9P2L0,O75880,P40939,P21912,P00403,O75431,Q96RR1 14 +Glomerulopathy 0.6483889873424548 1.8283521850223787 0.0674967125479004 1.0 0.2591779626581429 11 Q9NZ08,P06280,Q14108 3 +External ophthalmoplegia 0.5935884397226956 1.82823584156525 0.0675141640513574 1.0 0.2591779626581429 15 P12235,P03886,P00403 3 +Aplasia hypoplasia of the sternum 0.8106236539547866 1.824377336351554 0.0680950458867641 1.0 0.2601723545969625 4 Q9Y619 1 +Abnormality of the calf 0.3776931298692809 1.8171013157477829 0.0692016013451164 1.0 0.2633174773541449 66 Q7LGA3,Q32P28,P16435,P16278,Q9Y619,Q96L58,Q13535,Q13126,Q15427,Q9Y4P3,Q96HY6,O75718,Q9NR77,P08236 14 +Abnormal circulating metabolite concentration 0.2766069842668759 1.816700934317067 0.0692629186120947 1.0 0.2633351226446745 362 P11177,P61916,P48735,P51798,Q70HW3,Q13045,O43676,Q16134,Q15392,Q8N511,Q9UGP8,O75844,P23786,P07602,Q9Y619,P28288,P03886,P43243,Q5JRX3,O95470,Q15800,Q8N1F7,P05023,O96000,O60762,O14936,Q8NFH4,Q9UBM7,O14979,Q8NAT1,Q5XKP0,Q9Y584,Q16836,P36551,Q13423,P35658,Q9P0J0,Q9H9P8,P37268,Q86Y39,P11166,P00367,Q9Y487,P49257,Q9NWM8,Q9UJS0,P21912,Q15043,Q02978,P05067,P12235,P09001,Q14739,Q9UBS4,Q9P032,Q92621,Q86YH6,Q07021,Q6ZXV5,P40855,P13473,P35610,O14678,Q9NP80,Q96CU9,P53985,P06280,Q99707,P21964,Q99797,P08574,Q9BWD1,Q9Y4P3,P10253,Q9Y6M9,Q9NPL8,P31483,Q9NZJ7,P22626,Q96RL7,P14854,Q4J6C6,Q15120,Q13315,O95831,O75306,P50402,P22830,Q96EY8,Q9NVI7,P42858,O75648,Q6NUQ1,O75845,O43772,P23378,Q9Y2Z2,Q12769,Q6PGP7,Q14376,Q15904,Q9BT22,Q96MF7 103 +Myoclonic seizure 0.3840667183224384 1.8158767430643303 0.0693892816156478 1.0 0.2634301904827238 60 O43292,P07602,P03886,P16278,O75503,Q9Y619,Q9NZJ7,Q13510,Q96N66,P04062 10 +Abnormal endocrine physiology 0.7899459370191362 1.815554473611423 0.0694387426452132 1.0 0.2634301904827238 5 Q13423 1 +Abnormal ossification involving the femoral head and neck 0.7350449370736689 1.815428889246267 0.0694580248259442 1.0 0.2634301904827238 3 Q14739 1 +Progressive visual loss 0.5034255889626185 1.813460156042998 0.0697608786091998 1.0 0.2642396471320821 24 O14773,P03886,O75503,Q99519,P50897,O60313 6 +Respiratory failure requiring assisted ventilation 0.7894016933245231 1.8131539773471776 0.0698080758910024 1.0 0.2642396471320821 5 P10253 1 +Weight loss 0.349780981359987 1.8125649296825728 0.0698989509955507 1.0 0.2642396471320821 78 Q06136,O15460,Q13315,Q13423,Q01844,Q99720,P04062,O75844,P07602,Q9NZ08,P42858,P42892,O15360,Q9NZJ7,Q13535,Q96RL7,P35637,P01889,P35610 19 +Endocarditis 0.7884970824570148 1.8091630001920975 0.0704256839242958 1.0 0.2656729436824313 5 Q9NZ08,P04062 2 +Focal segmental glomerulosclerosis 0.515527080147994 1.8072730045962992 0.0707197229770038 1.0 0.2656729436824313 22 P03886,Q14108,P00403 3 +Paroxysmal ventricular tachycardia 0.7265866330022468 1.8071713649377577 0.0707355642133378 1.0 0.2656729436824313 7 Q9HD47,Q99959 2 +Recurrent acute respiratory tract infection 0.7878828439574246 1.8064523762891356 0.0708477066364188 1.0 0.2658433545377415 5 Q03519 1 +First degree atrioventricular block 0.7686297480965314 1.8060376511242615 0.070912458610401 1.0 0.2658433545377415 6 Q9HD47,Q99959 2 +Testicular dysgenesis 0.6601516919486627 1.8008689413097256 0.0717235393809119 1.0 0.2677767795939825 2 Q8IY37 1 +Loss of speech 0.5264308150953831 1.8006580114389734 0.0717567995252923 1.0 0.2677767795939825 20 P17900,P07602,P61916,Q9NZJ7,O15118,P50897 6 +Upper airway obstruction 0.7860038946954052 1.798157024204439 0.0721521277425818 1.0 0.2686047960673359 5 O75844,P16435 2 +Joint subluxation 0.7665967386400065 1.7967722856010615 0.0723717778588084 1.0 0.268740838347363 6 P16278,Q9UHX1 2 +Nodular goiter 0.659276546091021 1.796362377023248 0.0724369033295857 1.0 0.268740838347363 2 Q9UNW1 1 +Neoplasm of the tracheobronchial system 0.6592765460910013 1.796362377023146 0.0724369033296019 1.0 0.268740838347363 2 P30154 1 +Abnormal tongue morphology 0.3537165171201954 1.796104564799986 0.0724778886029371 1.0 0.268740838347363 76 Q7LGA3,O75844,P61978,Q10713,Q96RL7,P48651,P16278,O15460,Q99519,P01889,Q6DKJ4,Q9Y4P3,P10253,Q96A33,P98175 15 +Blurred vision 0.8036674361965204 1.7946042135851843 0.0727167813436033 1.0 0.2692817776196139 4 P03886,P04439 2 +Reduced consciousness confusion 0.3282732993880934 1.792639047628192 0.0730306585052562 1.0 0.2701436619549526 129 O14678,P36551,Q96CU9,Q13423,Q16134,O43676,P61313,P00403,P04062,O75306,P23786,P07602,P11166,Q86Y39,Q99567,Q9Y619,P00367,P49770,O43681,Q9NWS8,Q9NZ08,Q96EY8,P42858,Q9Y6M9,Q9NPL8,P03886,P05067,Q9NZJ7,P12235,O43772,P23378,O96000,Q9UBM7,P01889,Q16836,P35610 36 +Visual field defect 0.4060098779258375 1.7920941343307015 0.0731178883362821 1.0 0.270251160867436 41 P03886,Q9H061,O15460,P01889,P04439,O60313,Q9Y287,P00403 8 +Dilatation of the ventricular cavity 0.7295902325715966 1.7899177661961678 0.0734671322947022 1.0 0.2708954735247513 3 Q99959 1 +Abnormal choroid morphology 0.4554714042568827 1.788804279415919 0.0736463415129817 1.0 0.27134092202166 30 Q10713,Q12768,P53701,O14936,Q9H9S5,P40855,Q9Y619,Q5XKP0,P04439,Q8NAT1,O43505 11 +Social and occupational deterioration 0.802097841395756 1.7878766245929405 0.0737959149733176 1.0 0.2714734466969578 4 Q9BQE5 1 +Abnormal saccadic eye movements 0.4933659597037322 1.787856428191712 0.0737991741666503 1.0 0.2714734466969578 25 O75306,O14773,Q10713,Q96RL7,Q8IV08,P04062 6 +Abnormal chorioretinal morphology 0.4709544636644349 1.7843307091144336 0.074369943039563 1.0 0.2731728066891529 28 Q10713,Q12768,P53701,Q8IY17,Q9H9S5,O75381,O14936,Q9Y619,P40855,O15078,Q5XKP0,P04439,Q9P2D1,Q8NAT1,O43505,P40939 16 +Ventricular fibrillation 0.6787377966070282 1.7840023972103802 0.074423275629937 1.0 0.2731728066891529 8 Q9HD47,Q99959,Q14BN4 3 +Central apnea 0.666397887658598 1.7838886488990204 0.0744417607492406 1.0 0.2731728066891529 9 Q9NZJ7,Q10713,O76024,P07602 4 +Abnormal peripheral nervous system physiology 0.3846635333202214 1.7820310005754472 0.0747441764964125 1.0 0.2738654921154042 54 O15269,Q15120,P07602,Q8TB36,Q96RL7,O15270,Q9Y619,Q9NZJ7,Q99519,Q99720,Q9NR77,O60313 12 +Abnormal neuron morphology 0.470614547178993 1.7814193586531912 0.0748439680344321 1.0 0.2740150319054151 28 P31483,Q13510,Q15165,P35637,Q99720,Q92804 6 +Short nail 0.7628971164097906 1.779894277289387 0.075093264433677 1.0 0.2745973182377423 6 O75844,Q9Y487 2 +Atrophy degeneration involving the caudate nucleus 0.7994684630186025 1.7765987853963634 0.0756342756348025 1.0 0.2756053683131706 4 Q96RL7 1 +Oligosacchariduria 0.7199408785869325 1.7748677050947377 0.07591973382707 1.0 0.2757302242114807 7 P10253,P16278 2 +Anorexia 0.4773802287074374 1.7745699639323609 0.075968920352418 1.0 0.2757302242114807 27 O15460,Q13315,P01889,Q13423,P06280,P35610,Q9NZ08,Q14108,P04062 9 +Nail dysplasia 0.4334102872718935 1.7740394843775726 0.0760566194371754 1.0 0.2757302242114807 35 Q15022,P42892,O60762,P48651,P10321,Q9Y619,P16615,Q13535,O96028,O95202,Q6DKJ4,O60568 12 +Abnormal delivery 0.5105668574380245 1.7697819557381094 0.0767634709381628 1.0 0.276588546533507 22 O75844,O75718,Q9Y619,Q9Y487 4 +Mitochondrial respiratory chain defects 0.7795403208185372 1.7695803291645154 0.0767970781378011 1.0 0.276588546533507 5 O75306,P03886,Q4J6C6 3 +Lactic acidosis 0.3391168535001273 1.7669730490976812 0.0772327419452363 1.0 0.2775967611660477 91 P51970,P11177,Q5JPH6,Q9NP80,Q96CU9,Q70HW3,O43676,P00403,O75306,Q99797,Q10713,Q86Y39,P08574,Q9UJS0,Q9NWS8,Q9Y6M9,Q9NPL8,O75648,P03886,Q00325,P12235,Q9P032,Q9Y2Z2,Q86YH6,O96000,Q6P4A7,P14854,Q5XKP0,Q4J6C6,Q16836 30 +Intestinal malrotation 0.4437504508846817 1.7669461229451209 0.0772372516585584 1.0 0.2775967611660477 32 P55011,Q12768,Q00839,Q9UL01,O96028,O95202,Q15392,P21964,Q14739 9 +Abnormality of the pharynx 0.3845120224116302 1.7668326076196024 0.0772562660756994 1.0 0.2775967611660477 52 Q13510,P16278,O15460,P15586,Q13315,P01889,Q03519,P54802,Q03518,P21964,P08236 11 +Peroneal muscle atrophy 0.7783001374367277 1.7640901197114198 0.0777168076721679 1.0 0.2777829959845039 5 Q9NR77,Q96RL7 2 +Depression 0.336353999084947 1.7636767741032258 0.0777864136409469 1.0 0.2777829959845039 107 Q15165,O15460,P06280,P50897,P21964,P00403,P04062,P07602,O43681,Q9Y4P3,Q96N66,P42858,P55011,P03886,P43243,Q06787,Q9NZJ7,Q6DKK2,P12235,Q92804,O76024,Q96RL7,P35637,P01889,P51812,Q9NZ01 26 +Cardiomegaly 0.4139291409372417 1.7621484353846066 0.0780442216214412 1.0 0.2782083497321009 39 P23786,P13473,Q99519,P54802,Q9Y4P3,P10253,Q14739,P04062 8 +Cerebral inclusion bodies 0.5830735976768289 1.7619060784144105 0.0780851674667799 1.0 0.2782083497321009 15 P31483,P05067,O15118,P22626,Q9Y287,P04062 6 +Mutism 0.6091264464643937 1.7615202772141072 0.0781503840781197 1.0 0.2782273443884629 13 Q13510,P35637,P22626,P53701 4 +Abnormal pulmonary thoracic imaging finding 0.5094206555297749 1.761103270946783 0.078220925517592 1.0 0.2782652526452778 22 Q96L58,Q9NZ08,Q13510,P21964,P04062 5 +Abnormal lower motor neuron morphology 0.716900317070861 1.7600614931554976 0.0783973808072249 1.0 0.278655899304067 7 Q99720,P35637 2 +Abnormal heart rate variability 0.7955437673975132 1.7597471219996872 0.0784506922707102 1.0 0.278655899304067 4 P07602 1 +Specific learning disability 0.3691234631463772 1.7578629298191029 0.0787708346570208 1.0 0.2791527824687405 68 P04350,P42858,P42345,Q10713,P53701,P48651,P03886,Q06787,P35637,Q9Y619,Q8NAT1,P22626,P21964,P00403 14 +Diminished movement 0.5088106976827731 1.7564825483269828 0.0790060487137267 1.0 0.2797729438444927 22 O95831,Q99567,P13473,P51114,P12235,P04062,Q2TAA5 7 +Hypersplenism 0.6611935571374109 1.7560578464312449 0.0790785318303761 1.0 0.2798163433997926 9 Q14108,P07602,P04062 3 +Abnormal circulating non proteinogenic amino acid concentration 0.7155227924505385 1.7533481318991793 0.079542268358165 1.0 0.2803800054761178 7 P03886,Q9Y619 2 +Abnormality of the achilles tendon 0.5946950260419367 1.7519583740047766 0.0797809658285466 1.0 0.2803800054761178 14 Q8TD16,Q8WXH0,Q9H9S5,Q15041,P50402,O60313 6 +Microretrognathia 0.5812655119384864 1.7504662257614467 0.0800378971234341 1.0 0.2804101927272713 15 Q9UL01,Q15427,Q9UHX1,Q16625,Q8N201 5 +Pyelonephritis 0.6502333722287073 1.7497032530631886 0.0801695320849169 1.0 0.2804101927272713 2 Q9UBS4 1 +Abnormal glomerular filtration rate 0.6502333722287073 1.7497032530631886 0.0801695320849169 1.0 0.2804101927272713 2 Q9UBS4 1 +Germinoma 0.6499416569428288 1.748195397937217 0.0804301982283162 1.0 0.2804101927272713 2 Q9UPY3 1 +Retinal fold 0.649941656942828 1.7481953979372091 0.0804301982283175 1.0 0.2804101927272713 2 P52732 1 +Abnormal tendon morphology 0.3019855864411037 1.7440051568592094 0.0811581906254852 1.0 0.2811920411680483 223 Q7LGA3,Q8TB36,P50897,Q15392,Q6DKJ4,Q99720,P08236,P04062,Q86XL3,O75844,P23786,P49902,O95831,P37268,Q99567,Q9Y619,Q9UPT5,O15228,Q15043,P42892,P15586,Q9UL01,Q96L58,Q13535,Q96PU5,Q8IZA0,Q96AY3,P16435,P48651,P35637,Q96A33,Q13510,Q9NR77,O60313,O60568,Q14738 36 +Abnormal anterior eye segment morphology 0.2745534994607103 1.742131864033576 0.0814853731061167 1.0 0.2811920411680483 327 Q7LGA3,Q06136,Q92974,Q13045,P06280,O95202,Q16134,P21964,P08236,P00403,P04062,Q2TAA5,O75844,P23786,Q99797,Q10713,O43683,P53701,P16278,Q9NWM8,O15228,Q9Y4P3,Q9NZ08,P07437,Q9NVI7,Q9Y287,Q8N201,P42858,O75648,P03886,O15360,P61586,Q9UL01,Q99519,Q96L58,P08670,O96028,Q03519,O75569,P22626,Q15800,P12235,Q03518,Q16625,O75845,Q14739,P10619,O76024,Q6ZXV5,P51648,O14979,P01889,Q13126,Q8NAT1,P04439,Q96PZ0,Q9UHX1,Q13510,Q9NR77,O60313,O60568,Q14738 62 +Abnormal placenta morphology 0.6706669650858602 1.7418977459554543 0.0815263384507747 1.0 0.2811920411680483 8 O75844 1 +Tip toe gait 0.7192880070032098 1.7415988745508002 0.0815786584379956 1.0 0.2811920411680483 3 O75477,Q9ULH0 2 +Delayed cranial suture closure 0.4659045808730176 1.741013504975243 0.0816812113063023 1.0 0.2811920411680483 28 O75844,Q32P28,P16435,Q9Y487,O75718 5 +Dysesthesia 0.7128065113187319 1.7401005663364089 0.0818413608442134 1.0 0.2811920411680483 7 Q9NR77,Q06787,Q9UL01 3 +Choroidal melanoma 0.648191365227544 1.739144768173054 0.0820093017181888 1.0 0.2811920411680483 2 Q99496 1 +Photopsia 0.648191365227544 1.739144768173054 0.0820093017181888 1.0 0.2811920411680483 2 Q99496 1 +Inferior lens subluxation 0.648191365227544 1.739144768173054 0.0820093017181888 1.0 0.2811920411680483 2 Q99496 1 +Mydriasis 0.648191365227544 1.739144768173054 0.0820093017181888 1.0 0.2811920411680483 2 Q99496 1 +Metamorphopsia 0.648191365227544 1.739144768173054 0.0820093017181888 1.0 0.2811920411680483 2 Q99496 1 +Uveal melanoma 0.648191365227544 1.739144768173054 0.0820093017181888 1.0 0.2811920411680483 2 Q99496 1 +Aortic valve stenosis 0.6189609236794873 1.7378531686280057 0.0822366893392549 1.0 0.2813487913624291 12 O75844,P04062 2 +Abnormal thyroid stimulating hormone level 0.6476079346557819 1.736126565558617 0.0825414580648484 1.0 0.2815621249407893 2 O14654 1 +Congenital craniofacial dysostosis 0.6476079346557653 1.736126565558533 0.0825414580648633 1.0 0.2815621249407893 2 Q6NUK1 1 +Vertebral compression fracture 0.5511849709864566 1.7328008184348256 0.0831310773506004 1.0 0.2833653597732132 17 Q32P28,Q96AY3,O75718,Q14108,P04062 5 +Localized osteoporosis 0.6464410735122583 1.7300881853327672 0.0836145207747369 1.0 0.2845956509299838 2 P82650 1 +Sick sinus syndrome 0.7700747510473106 1.7276202130584288 0.08405633649912 1.0 0.2856808627468263 5 Q9HD47,Q99959 2 +Erythema 0.5107945846772846 1.7272095409493178 0.0841300379651379 1.0 0.2857223365394963 21 Q06136,P53701,P03886,P51648,P01889,P00403 6 +Depletion of mitochondrial dna in muscle tissue 0.7875150302690086 1.7252080338294011 0.084489988394123 1.0 0.286525902247515 4 Q9UBX3 1 +Enlarged ovaries 0.715627726057358 1.7243900335425215 0.0846374555584736 1.0 0.2868166437087299 3 P16435 1 +Dilated cardiomyopathy 0.3824557486295535 1.7226449452425752 0.0849527519318396 1.0 0.2871139169973218 46 P23786,Q96RL7,P53701,P03886,P16278,P13473,P12235,P00403 8 +Nasal regurgitation 0.6449824970828522 1.7225365314857666 0.0849723710441923 1.0 0.2871139169973218 2 P53007 1 +Head titubation 0.7084512958216367 1.7188330686939548 0.0856447722722455 1.0 0.2884334868557485 7 Q99720,P35637 2 +Cataplexy 0.7859989801124363 1.7186763927169433 0.08567331292745 1.0 0.2884334868557485 4 O15118 1 +Macrovesicular hepatic steatosis 0.7491089548260863 1.71680232683373 0.0860152956775173 1.0 0.2889788368071293 6 Q5XKP0,P23786,O75648 3 +Splanchnic vein thrombosis 0.6432322053675672 1.713469201600824 0.0866262546767506 1.0 0.2897520368813416 2 P35222 1 +Portal vein thrombosis 0.6432322053675672 1.713469201600824 0.0866262546767506 1.0 0.2897520368813416 2 P35222 1 +Epigastric pain 0.6432322053675672 1.713469201600824 0.0866262546767506 1.0 0.2897520368813416 2 P35222 1 +Stroke 0.4271124557098701 1.7127821744608482 0.0867526207035687 1.0 0.2899659538048778 35 O75844,P51970,P03886,P05067,Q96L58,P06280,Q9Y4P3,P00403 8 +Abnormal vascular morphology 0.2978456912408304 1.7122326461025044 0.0868538034483894 1.0 0.2900954499074172 248 Q7LGA3,P61978,O14678,P61916,P38435,P51798,O15460,P06865,P51571,Q6DKJ4,Q15392,P98175,P21964,P08236,Q9UGP8,P04062,O75844,O43683,Q12768,P07602,P53701,P16278,Q9Y487,Q9NWM8,Q15427,Q9Y4P3,P10253,Q9NZ08,Q6NUK1,P42858,P17900,O75648,P55011,P42892,P03886,Q06787,O15360,P05067,Q9NZJ7,Q99519,Q96L58,Q96PU5,O75845,O75718,P10619,P48651,Q6ZXV5,Q6PGP7,O15118,P01889,Q96PZ0,Q96MF7,Q9UHX1,Q13510,O60568 55 +Impaired distal tactile sensation 0.7121151729665116 1.7078558596150724 0.0876630912189924 1.0 0.2917498007187957 3 O15269 1 +Emg slow motor conduction 0.7121151729665116 1.7078558596150724 0.0876630912189924 1.0 0.2917498007187957 3 O15269 1 +Trophic changes related to pain 0.7121151729665116 1.7078558596150724 0.0876630912189924 1.0 0.2917498007187957 3 O15269 1 +Penetrating foot ulcers 0.7121151729665116 1.7078558596150724 0.0876630912189924 1.0 0.2917498007187957 3 O15269 1 +Abnormal placental size 0.7824863780804258 1.7035313782782953 0.0884686710171802 1.0 0.2942200755517677 4 O75844 1 +Truncal titubation 0.641190198366401 1.7028833645858668 0.0885898977760457 1.0 0.2944124928952136 2 Q9BYI3 1 +Areflexia of lower limbs 0.513002922732039 1.7025337007117551 0.0886553665186646 1.0 0.294419465936895 20 Q15120,Q96RL7,Q9NR77,P12235,O75477,O60313,Q15067 7 +Papule 0.5181235306585508 1.7016076439790149 0.0888289436267286 1.0 0.2946246974547439 19 O75844,P38435,Q9NZ08,P16615 4 +Agitation 0.4332928565640833 1.7013811556743494 0.0888714375193953 1.0 0.2946246974547439 33 P42892,Q15165,P35637,P05067,P04062,Q92804 6 +Abdominal distention 0.4612760093408053 1.701189495228751 0.0889074097786377 1.0 0.2946246974547439 28 P42345,O75648,P07602,Q13277,Q9NZJ7,O43681,Q01844,Q96HY6,Q9UGP8,P04062 10 +Emg chronic denervation signs 0.6121971970282575 1.698460315752472 0.0894209165232808 1.0 0.2952733320306773 12 P07602,Q9NZJ7,P22626,Q13510,O60313 5 +Spasticity 0.2725154085717932 1.6953863406839746 0.090002155394292 1.0 0.2965552525329707 328 Q8TD16,P51970,P61916,Q9NP80,Q5JPH6,O95630,Q15165,Q96CU9,Q9UBX3,Q7KZN9,Q8WVX9,Q13315,P50897,Q15392,Q8TAF3,Q15907,Q99720,P35658,Q9P0J0,P04062,P49902,Q86XL3,Q2TAA5,O95831,Q10713,O75306,P07602,Q15022,Q12768,Q9H9P8,Q96KP1,P16278,Q9Y619,Q9Y487,P49770,O43681,Q9Y4P3,Q96N66,Q9Y287,Q9NVI7,O75477,Q15043,P04350,P42858,P17900,O43292,Q96D71,P55011,P03886,P43243,Q9NZJ7,Q99519,Q6DKK2,Q16625,O00584,Q92804,Q9Y2Z2,O60762,Q6ZXV5,O14936,O75503,P51648,P35637,P51812,O15118,P11117,Q5XKP0,O60313,Q13510,Q9H490,P35610,Q9Y320,Q9NZ01 73 +Abnormal exteroceptive sensation 0.3764906213478127 1.6949794903023083 0.0900793115687164 1.0 0.2965552525329707 56 O15269,P61978,P07602,O15270,Q06787,P05067,O15460,Q9NZJ7,Q9UL01,P01889,P06280,P54802,Q9NZ08,Q9NR77 14 +Bone marrow foam cells 0.7802170956653018 1.6937386054409087 0.0903149650621299 1.0 0.2965644435297058 4 O15118,Q99519 2 +Abnormal enchondral ossification 0.444912820639414 1.6936985724091962 0.0903225758920649 1.0 0.2965644435297058 30 P38435,Q9Y619,Q99519,Q96L58,O96028,O95202,Q96HY6,P08236,Q14739 9 +Tongue fasciculations 0.5976478316255031 1.6927256651252656 0.0905076976704748 1.0 0.2969624035148489 13 P51114,Q9NWS8,Q13510,Q9BQT8,O95831 5 +Opisthotonus 0.4600833918680549 1.6909100454980135 0.0908539844091078 1.0 0.2976942472900109 28 P07602,P35637,Q9NZJ7,P11117,Q99720,O60313,P04062,Q2TAA5 8 +Abnormal respiratory system morphology 0.2719502075248404 1.6908843202049528 0.0908588985486946 1.0 0.2976942472900109 329 Q7LGA3,Q15165,P51798,O15460,Q13315,P30154,Q13045,P06280,O95202,Q6DKJ4,Q15392,Q01844,Q16134,P98175,P21964,P08236,Q9H0U3,P04062,O75844,O43683,Q12768,P07602,Q99567,P16278,Q13277,Q9Y487,Q9UJW0,Q15427,Q9Y4P3,P10253,Q9NZ08,P09601,Q14108,Q16637,Q6NUK1,P42858,Q9NPL8,O75648,P55011,P43243,Q06787,O15360,P15586,Q9UL01,Q9NZJ7,Q99519,Q96L58,O96028,Q03519,P54802,O75718,Q03518,Q8N1F7,Q8IZA0,Q14739,Q92804,Q8TAA9,Q12769,P16435,Q6PGP7,O96000,Q8NFH4,P35637,P01889,Q96PZ0,Q9UHX1,Q96HY6,Q13510,Q8N5M9 69 +Abnormality of the autonomic nervous system 0.373552267824944 1.690215884487804 0.090986660539958 1.0 0.2979027659398486 61 O15269,Q10713,P07602,P42892,Q96RL7,O15270,O15360,Q06787,Q9NZJ7,P06280,Q15427,P21964,P04062,Q15067 14 +Hyperthyroidism 0.64842666532962 1.6875438951593151 0.0914988169660437 1.0 0.2993686645241122 9 P12235,Q06787 2 +Premature rupture of membranes 0.7423685966866598 1.6858554681323068 0.0918236409928536 1.0 0.3002200112968319 6 O75844 1 +Abnormal autonomic nervous system physiology 0.4241445997099875 1.683823820986624 0.092215722127487 1.0 0.301046793790523 35 P07602,P42892,Q06787,Q9NZJ7,P06280,P04062,Q15067 7 +Abnormality of salivation 0.3790887508668785 1.683727654769704 0.0922343142208226 1.0 0.301046793790523 44 P55795,Q96RL7,Q15165,P35637,P15586,Q9NR77,Q14739,Q92804 8 +Decreased specific antibody response to protein vaccine 0.6373978996499462 1.683203497080067 0.0923357040790993 1.0 0.301046793790523 2 P17812 1 +Abnormality of the pulmonary veins 0.6593161440426489 1.68246284076597 0.0924791246911636 1.0 0.3013029546389523 8 Q15392 1 +Reduced tendon reflexes 0.3071484758150409 1.6765856924629936 0.0936235264837139 1.0 0.3043911154956858 177 P61978,Q15120,P11177,Q8TB36,Q92974,Q13315,Q13045,Q99720,Q9BQT8,P04062,O95831,O15269,Q10713,P07602,P50402,O43681,Q9NWS8,P10253,O75477,Q15067,O75648,P03886,Q06787,Q9NZJ7,P51114,P54802,P12235,P23378,Q8TAA9,Q96AY3,Q96RL7,P35637,O14979,Q9BT22,Q8NAT1,O60313,Q13510,Q9NR77,P35610,Q14738 40 +Upper limb postural tremor 0.775841741815223 1.6748389380110258 0.0939658368199949 1.0 0.3046890627031443 4 Q9NR77 1 +Clonic seizure 0.6993991028226124 1.6745271299648548 0.0940270470776578 1.0 0.3046890627031443 7 Q9NZJ7,P07602 2 +Abnormal sternal ossification 0.7757421225837269 1.674408346399106 0.0940503735905777 1.0 0.3046890627031443 4 O96028,Q9Y619 2 +Eeg with focal spike waves 0.6356476079346484 1.674111675011868 0.094108653676068 1.0 0.3046890627031443 2 P11166 1 +Eeg with irregular generalized spike and wave complexes 0.6356476079346484 1.674111675011868 0.094108653676068 1.0 0.3046890627031443 2 P11166 1 +Generalized myoclonic atonic seizure 0.6356476079346484 1.674111675011868 0.094108653676068 1.0 0.3046890627031443 2 P11166 1 +Hyperextensible skin 0.5422916828320824 1.6727799423174046 0.0943706248551641 1.0 0.30489980742496 17 Q9NWM8,P04062,Q9UHX1,Q9UL01 4 +Progressive pes cavus 0.704081454559236 1.6699688299490776 0.0949255307903262 1.0 0.3062666778137888 3 Q12768 1 +Slurred speech 0.6324265256959466 1.6669826666174314 0.0955178515574912 1.0 0.307750303977881 10 P16278,Q9Y487,Q99519 3 +Progressive peripheral neuropathy 0.7735320150600524 1.6648522846173734 0.0959422297625307 1.0 0.3086894733218268 4 Q9NZJ7,P07602 2 +Chronic pulmonary obstruction 0.6970653897982018 1.6630831480410295 0.0962957926942313 1.0 0.3091398172888714 7 P09601,P06280 2 +Meningitis 0.6968975407660012 1.6622597226200082 0.0964607098940004 1.0 0.3092867206125094 7 P01889,Q9NZ08,O15460 3 +Pulmonary infiltrates 0.6965881467368986 1.660741796441059 0.096765315168275 1.0 0.3098357369206104 7 Q9NZ08,Q13510,P04062 3 +Enchondroma 0.6311333973068305 1.6598300279206282 0.0969486511060764 1.0 0.3102089759220599 10 O75874 1 +Cutis laxa 0.4409573276508661 1.657904066600281 0.0973368312371099 1.0 0.3107387082953882 30 Q6NUK1,Q15022,O96000,P48651,P38435,Q15904,Q9Y487,Q9UL01,Q96L58,Q9Y4P3 10 +Abnormality of muscle size 0.2984548456649071 1.6578190950355791 0.0973539859476833 1.0 0.3107387082953882 209 Q7LGA3,P51970,P61978,Q15120,Q8TB36,Q15165,Q13315,Q99720,Q9BQT8,O95831,O15269,Q10713,Q99567,P16278,O15270,Q9Y487,P50402,Q9NWM8,Q9Y4P3,P10253,Q9NVI7,Q9NPL8,P31483,Q99519,Q6DKK2,P22626,P12235,Q92804,Q96RL7,Q6P4A7,P35637,P13473,O14979,Q13126,Q8NAT1,Q96A33,Q13510,Q9NR77,O60313,O60568 40 +Hypopigmented skin patches 0.4772129025705976 1.657681652702842 0.0973817389750506 1.0 0.3107387082953882 25 P42345,P07602,P53701,Q9NZJ7,P21964,Q8IZA0 6 +Biliary cirrhosis 0.654490049559172 1.6571187645879066 0.0974954660868765 1.0 0.3108514865813734 8 P09601,Q9UJW0 2 +Venous thrombosis 0.5534090589052818 1.656844601585001 0.0975508969943268 1.0 0.3108514865813734 16 Q9NZ08,O75874,P48735 3 +Abnormal pyramidal sign 0.3211462820237682 1.6564532800394325 0.097630058915596 1.0 0.310890509747676 128 O75027,P18074,P04066,Q8WVX9,Q8NI60,Q99720,P49327,Q9P0J0,O95831,P49902,Q9H9P8,O14773,O75306,Q9BYI3,Q12768,P07602,Q8TB37,P11166,P52701,Q9Y619,Q8N0X7,O43681,Q9UEY8,Q9NZ08,O75477,P21912,P54886,Q15043,Q15067,P42858,P17900,P51572,Q5TBB1,Q9H9S5,Q9NZJ7,Q6DKK2,O75569,Q9Y5W7,Q04446,P35637,P51648,P01889,P51812,Q9NR77,O60313 45 +Abnormal periventricular white matter morphology 0.3764854884716049 1.6538534718325897 0.0981572883129908 1.0 0.3121415205353563 44 P17900,O75648,P07602,P11177,O75503,Q9NZJ7,P51571,O96028,O95202,Q9UHX1,O60313 11 +Abnormality of pelvic girdle bone morphology 0.3148018811720477 1.6530815985491574 0.0983142578322031 1.0 0.3124268412369466 157 Q7LGA3,P61978,P51798,O95202,Q15907,Q6DKJ4,P08236,O95831,O75844,Q12768,P16278,Q9Y619,Q9Y487,O15228,Q15427,Q9Y4P3,Q9NVI7,P42858,O75648,P55011,Q6NUQ1,O15360,Q96L58,Q13535,O96028,O75718,Q14739,Q8IZA0,Q8TAA9,Q96HY6,Q96AY3,P16435,Q9Y366,Q9UBM7,P01889,Q96PZ0,Q9UHX1,Q9Y584,P51812,Q96A33,Q14738 41 +Abnormal st segment 0.7344429185269303 1.649383481749921 0.0990690966018243 1.0 0.3141745465687511 6 Q9HD47,Q99959,Q14BN4 3 +St segment elevation 0.7344429185269303 1.649383481749921 0.0990690966018243 1.0 0.3141745465687511 6 Q9HD47,Q99959,Q14BN4 3 +Aphasia 0.3925602518514258 1.647058485702809 0.0995460250359028 1.0 0.3147398548455533 41 Q7LGA3,P42858,O75648,P31483,P53701,P03886,P05067,P22626,P21964,P00403 10 +Partial absence of thumb 0.6303967327888047 1.646803754655787 0.0995983893780163 1.0 0.3147398548455533 2 Q9BXW9 1 +Aplasia of the proximal phalanges of the hand 0.6303967327888047 1.646803754655787 0.0995983893780163 1.0 0.3147398548455533 2 Q9BXW9 1 +Aplasia of metacarpal bones 0.6303967327888047 1.646803754655787 0.0995983893780163 1.0 0.3147398548455533 2 Q9BXW9 1 +Abnormal liver morphology 0.2956632697281195 1.645897194913725 0.0997849265802797 1.0 0.3147398548455533 244 P61916,P51798,Q7KZN9,Q96CU9,O43676,Q16134,Q01844,Q9H0U3,Q8N511,P08236,P04062,O75306,P23786,Q10713,P07602,Q86Y39,P16278,Q9Y619,Q9UJW0,Q9NWS8,P22830,P10253,Q96EY8,P09601,Q14108,Q9NVI7,Q15067,Q9Y6M9,Q9NPL8,O75648,Q6NUQ1,P03886,P00374,P15586,Q9NZJ7,Q99519,O75845,P54802,P22626,O43772,Q16625,Q14739,Q9BW92,P10619,Q96RL7,Q6PGP7,Q14376,Q15904,Q5HYI8,Q9BT22,O15118,Q96MF7,Q96HY6,Q96A33,Q13510,P35610 56 +Intracellular accumulation of autofluorescent lipopigment storage material 0.6989852254328968 1.6458856580892 0.0997873022357942 1.0 0.3147398548455533 3 O75503 1 +Abnormality of peripheral nerves 0.3750765588571875 1.645145621266204 0.0999397844211489 1.0 0.3150069460113011 50 O15269,Q15120,P07602,Q8TB36,Q96RL7,O15270,Q9Y619,Q9NZJ7,Q99519,Q99720,Q9NR77 11 +Arthrogryposis multiplex congenita 0.4075626747089648 1.6447586683477422 0.1000195887625543 1.0 0.3150447521293745 38 O75844,Q99567,P04062,Q15392 4 +Arm dystonia 0.7680346773659975 1.6410571975382493 0.100785542608818 1.0 0.3170275091134518 4 Q99720 1 +Slow saccadic eye movements 0.6150972950565528 1.6400895203742325 0.1009865550421855 1.0 0.3174448814113627 11 Q8IV08,P04062 2 +Malrotation of small bowel 0.7673036307454194 1.637890171386492 0.1014446066280503 1.0 0.318669129407655 4 O96028,Q9UL01 2 +Abnormality of the peripheral nervous system 0.3288400930498461 1.636857592946935 0.1016602285255983 1.0 0.3191306903580606 106 Q15120,Q8TB36,P06280,Q99720,P21964,P04062,O95831,O15269,Q10713,P07602,O15270,Q9Y619,Q15427,Q15067,P42892,Q06787,O15360,Q9NZJ7,Q99519,Q96RL7,Q9NR77,O60313 22 +Abnormalities of placenta or umbilical cord 0.5501077267742451 1.6351584500040457 0.1020158358061926 1.0 0.3195991727279644 16 O75844,Q6PGP7,P16278,P16435 4 +Recurrent hand flapping 0.7659955944967907 1.6322219629912211 0.102632735632012 1.0 0.321139503141464 4 P55795 1 +J shaped sella turcica 0.7659319192243292 1.6319459835276602 0.1026908658749143 1.0 0.321139503141464 4 P08236 1 +Abnormal pattern of respiration 0.2965704815896554 1.6318320416783636 0.1027148733681049 1.0 0.321139503141464 194 P51970,P61978,O14678,Q15165,P51798,Q7KZN9,Q96CU9,P51571,P06280,Q16134,P98175,P04062,Q9P0J0,O75844,P23786,O95831,O75306,O43683,Q10713,P07602,P53701,Q86Y39,Q9Y619,P10253,Q96EY8,P04350,O75648,P03886,P43243,Q9NZJ7,Q96L58,P51114,Q00325,P12235,O43772,Q92804,O76024,O60762,O14936,Q9Y366,P35637,Q8TCJ2,P01889,Q9UHX1,Q03154,O60313,Q96A33,Q13510,P35610 49 +Ovoid vertebral bodies 0.6906094640855142 1.6313804611768 0.1028100650760541 1.0 0.3212209565187274 7 P16278,P15586,P54802 3 +Generalized clonic seizure 0.7304023343950309 1.6307565929188574 0.1029416898989992 1.0 0.3214160559615258 6 Q9NZJ7,P07602 2 +Hip pain 0.7480556300644643 1.6295325932882612 0.1032003208678249 1.0 0.3215975833320866 5 O75844 1 +Joint dislocation 0.3300772642109153 1.6289684004377838 0.1033197085707475 1.0 0.321731478565478 95 O75844,Q6ZXV5,Q9Y619,Q9Y487,Q9UL01,Q96L58,Q13535,P51571,Q96PU5,O96028,O95202,Q9UHX1,Q15427,Q96A33,P21964,Q9Y4P3,Q14738 17 +Wide nasal ridge 0.7649270645251751 1.6275901517088291 0.1036118187370171 1.0 0.3222091766078861 4 Q15022,P61978 2 +Neck muscle weakness 0.5613827515617684 1.6240485722968891 0.1043654425151014 1.0 0.3239023686874826 15 Q99720,P35637,P07602 3 +Biliary tract neoplasm 0.7465179379932485 1.6226593222880712 0.1046622515875195 1.0 0.3243901406775288 5 Q9NZJ7,P07602 2 +Neoplasm of the gallbladder 0.7465179379932485 1.6226593222880712 0.1046622515875195 1.0 0.3243901406775288 5 Q9NZJ7,P07602 2 +Ectopic anus 0.5470284885702011 1.6149038429923432 0.10633151991261 1.0 0.3279251639097216 16 Q15022,Q12768,P53701,P48651,P16435,Q6DKJ4 6 +Functional motor deficit 0.3153858388867949 1.612190704814348 0.1069204473500056 1.0 0.328365169458206 147 P61978,Q9Y2R0,Q15907,Q8TAF3,Q99720,P00403,P04062,P23786,O14773,P07602,P53701,Q9H2D1,Q9NWM8,Q15067,O43292,P31483,P03886,Q9NZJ7,P12235,Q96RL7,P35637,P13473,Q13510,Q9NR77 24 +Alkalosis 0.7441744272840509 1.612178636521937 0.1069230727164718 1.0 0.328365169458206 5 Q9Y619 1 +Low set posteriorly rotated ears 0.3520978371743108 1.6121272832314917 0.1069342448106469 1.0 0.328365169458206 71 Q9UM00,O95202,Q6DKJ4,Q15392,P98175,P04062,Q15022,Q10713,O43683,P37268,Q15427,Q9Y4P3,P07437,Q6NUK1,Q9UL01,Q96L58,O96028,P16435,Q9UBM7,Q4J6C6 20 +Epiphyseal stippling 0.5969354393739219 1.609183893656367 0.1075761371689807 1.0 0.329586975039483 12 P38435,Q9UBM7,Q99519,P08236,Q14739 5 +Hypocholesterolemia 0.6338836284493619 1.6091079150949787 0.10759274683125 1.0 0.329586975039483 9 P37268,P07602,Q9NZJ7,Q15800,Q9NVI7 5 +Cardiorespiratory arrest 0.743254815783398 1.608064138615624 0.1078211323018241 1.0 0.329637201612147 5 Q96L58,P13473 2 +Abnormality of pancreas physiology 0.3721639766824628 1.604140005935401 0.108683195307266 1.0 0.330892611662882 44 P03886,Q15904,Q5HYI8,P53985,P01889,Q9UJW0,Q9UHX1,Q9NZ08,P09601,P00403,Q14739 11 +Impaired temperature sensation 0.7244924771636749 1.603473889373486 0.108830069294121 1.0 0.3311227910546736 6 O15269,Q9NR77 2 +Mediastinal lymphadenopathy 0.7411844773114222 1.5987974410202077 0.1098656178437169 1.0 0.3335428026869356 5 P01889,O15460,Q01844 3 +Involuntary movements 0.268333947468257 1.5983817614027007 0.109958041144083 1.0 0.3335428026869356 352 Q15120,P61916,O95630,Q96CU9,Q9UBX3,P51798,Q13315,Q13045,P06280,O95202,P50897,Q15907,Q99720,O14949,P00403,Q9P0J0,P04062,Q9BQT8,O95831,O14773,O75306,Q10713,Q12768,P07602,Q9Y619,Q9BWD1,O43681,Q9NWS8,Q9Y4P3,Q96N66,Q14108,Q9Y287,O75477,Q15043,P04350,P42858,P17900,O43292,P55795,Q9NPL8,Q16637,P03886,Q06787,P00374,P05067,Q9NZJ7,Q99519,Q6DKK2,P13073,P51114,Q5JRX3,O96028,O75569,P12235,P22626,O75845,P23378,O00584,O76024,Q96RL7,Q6P4A7,O75503,P35637,P27544,Q9UHX1,Q13510,Q9NR77,O60313,Q14738 69 +Mortality aging 0.3254270272907067 1.5980629426521424 0.1100289697678207 1.0 0.3335428026869356 110 Q16134,Q6DKJ4,P04062,O75844,Q12768,P07602,P16278,Q13277,Q9NWS8,Q9Y4P3,Q9NVI7,Q15067,Q6NUK1,Q9NPL8,Q6NUQ1,P05067,Q9NXE4,Q9NZJ7,P51114,O75718,P23378,Q14739,O96000,P16435,Q15904,Q9BT22,Q8TCJ2,P51812 28 +Delayed puberty 0.3677671749324807 1.5976023710838747 0.1101314984226979 1.0 0.3335428026869356 58 O75844,O76024,P16435,Q13315,P06280,Q15800,Q9NVI7,Q14108,P04062 9 +Pericarditis 0.7402867330961723 1.5947776429140896 0.1107619682560037 1.0 0.3347166376789495 5 P01889,Q9NZ08 2 +Myopathy 0.3269063345940758 1.5920732371044295 0.1113682496976156 1.0 0.3362033061046927 102 O43676,P00403,O75306,P23786,Q86Y39,P50402,Q9NWM8,Q9NWS8,Q9Y4P3,O75648,P31483,P03886,Q9UL01,P51114,Q00325,P12235,P22626,Q96RL7,P13473,O14979,Q13126,O60313 22 +Abnormal aortic valve physiology 0.3765953142188397 1.5904980840813194 0.1117225771467063 1.0 0.3368352325915623 43 O75844,O43683,Q6PGP7,Q6ZXV5,P16278,P01889,Q96PU5,Q9UHX1,Q9Y4P3,Q9NZ08,P04062 11 +Hypoplastic hippocampus 0.6871899620659392 1.590007041405443 0.1118332178557965 1.0 0.3369501492594234 3 Q9UID3,Q96RL7 2 +Abnormal visual electrophysiology 0.3704081573556162 1.589612505067359 0.1119221765673992 1.0 0.3369996321011904 50 O14773,P07602,O75503,P51798,Q92974,Q9NZJ7,P14854,P50897,P12235,O60313,Q15067 11 +Rhizomelia 0.555690935416224 1.5876642942973649 0.1123622711139531 1.0 0.3376946648642851 15 P42345,Q9Y366,Q9UBM7,O15228,Q15392,O75718,Q14739 7 +Polyneuropathy 0.5297358672415672 1.587625442210246 0.1123710615325408 1.0 0.3376946648642851 17 Q15120,P07602,P03886,Q9NZJ7,O60313 5 +Upper limb spasticity 0.641178547053644 1.587001602709665 0.1125122816355317 1.0 0.3379004915828574 8 Q5T160,Q99720,P35637,Q12768 4 +Beaking of vertebral bodies 0.6176200778308415 1.584889709077531 0.1129913950760621 1.0 0.339120168942755 10 Q96L58,P16278,Q6NUQ1,P08236 4 +Metatarsus adductus 0.5795007330916204 1.5833051200415271 0.113351936502974 1.0 0.3397632883824628 13 Q96L58,O96028,P08236,Q15392 4 +Uterus didelphys 0.6845637583892691 1.577540961773752 0.1146711046712856 1.0 0.3407302939194085 3 O14974,Q9P2L0 2 +Lethal skeletal dysplasia 0.6845637583892369 1.5775409617735985 0.1146711046713209 1.0 0.3407302939194085 3 Q9P2L0,Q14739 2 +Abnormal pelvis bone ossification 0.6845637583892369 1.5775409617735985 0.1146711046713209 1.0 0.3407302939194085 3 Q9P2L0,Q14739 2 +Abnormality of the anterior fontanelle 0.4202690773922938 1.5774513098815517 0.1146917171349468 1.0 0.3407302939194085 33 Q32P28,P16435,Q9Y619,Q9Y487,Q13535,O75718,Q14738 7 +Thoracic kyphosis 0.5147720663687577 1.5773831318102214 0.1147073943608798 1.0 0.3407302939194085 18 P51648,P08236,Q9UHX1,P04062 4 +Abnormal mitochondrial number 0.6169778296382682 1.57680850522271 0.11483959403657 1.0 0.3407302939194085 2 P46976 1 +Progressive gait ataxia 0.5913615945231667 1.5764536075665223 0.1149213023184918 1.0 0.3407302939194085 12 O14773,P07602,Q9NZJ7,O43681,P54886,O15020,Q96RR1 7 +Ulnar claw 0.75249239561228 1.573595309983146 0.1155810382192332 1.0 0.3414422627051571 4 Q9NR77 1 +Pancreatic islet cell hyperplasia 0.6828903999845555 1.569593392966528 0.1165097365903951 1.0 0.3414422627051571 3 Q14739 1 +Abnormal involuntary eye movements 0.2735792653020764 1.5682221807489072 0.1168292896714771 1.0 0.3416114892079034 313 Q7LGA3,P78318,Q9H061,Q96CU9,O15460,P51798,Q13315,Q7KZN9,Q92974,O43676,Q15907,Q15392,Q8TAF3,Q99707,Q99720,O95202,Q9P0J0,P04062,P49902,O95831,O14773,O75306,Q10713,P07602,Q86Y39,Q13277,Q9Y4P3,Q9NVI7,Q96D71,Q15067,P04350,P42858,P17900,O43292,Q9Y6M9,Q9NPL8,O75648,Q6NUK1,P55011,P03886,Q06787,O15360,P61586,Q9NZJ7,Q99519,Q6DKK2,O96028,Q6P4Q7,P12235,O43772,Q16625,O00584,O76024,O96000,O60762,O14936,Q9H490,O75503,P35637,Q9Y366,Q9BT22,Q9UBM7,P01889,Q96PZ0,Q5XKP0,Q8IV08,Q13510,Q9NR77,O60313,Q14738 70 +Anophthalmia 0.6145532656781885 1.5678353667218163 0.1169195588037053 1.0 0.3416114892079034 10 P53701,Q9H9S5,O15078,Q8NAT1,Q9P2D1,O75569,O43505,Q96N67 8 +Overlapping toe 0.4782861422361727 1.5672480911507063 0.1170567134780418 1.0 0.3416114892079034 23 P61978,Q9UBM7,Q15427,Q15907,Q9UHX1,Q96A33,Q8N201 7 +Wormian bones 0.494188765917577 1.5639111126827594 0.1178384444078801 1.0 0.3431058646424383 20 O75844,Q32P28,Q96AY3,Q9Y487,O75718 5 +Ventricular tachycardia 0.5261181474818429 1.5630062088542098 0.1180511344439101 1.0 0.3431058646424383 17 P23786,Q9HD47,Q99959,Q14BN4,O43772 5 +Gastroesophageal reflux 0.3146204891871424 1.5611287514325285 0.1184933755214894 1.0 0.3434880421813432 131 O14678,P51571,P21964,O15269,P07602,O15270,Q9Y619,Q9Y4P3,P55795,Q06787,Q9NZJ7,Q96PU5,O96028,P12235,Q14739,Q8IZA0,P16435,Q6ZXV5,Q9UHX1,Q9Y584,Q96A33 21 +Abnormality of body mass index 0.6810621534870005 1.5609063048708778 0.1185458594862138 1.0 0.3434880421813432 3 P42858,Q9UJS0 2 +Abnormal oral mucosa morphology 0.3623415429948973 1.5608455826914218 0.1185601894228149 1.0 0.3434880421813432 63 P16278,Q14108,Q99519,P01889,Q14739,Q6DKJ4,Q15392,Q9NZ08,P08236,Q9Y4P3,P04062 11 +Vacuolated lymphocytes 0.7495357084534675 1.5607323386989806 0.1185869177053109 1.0 0.3434880421813432 4 P16278 1 +Weakness due to upper motor neuron dysfunction 0.3116824038234743 1.560189233855178 0.1187151690688712 1.0 0.3435540714827029 151 P51970,Q9NP80,Q96CU9,Q9UBX3,Q13423,Q8TAF3,P00403,Q9P0J0,P04062,P49902,O95831,P07602,Q9Y619,Q9NZ08,P17900,P03886,Q9NZJ7,Q96L58,Q6DKK2,P42345,P35637,P01889,Q13510,O60313 24 +Exaggerated startle response 0.6241193702505328 1.5562342475468127 0.1196524003487637 1.0 0.3454972355626827 9 P17900,P16278 2 +Focal white matter lesions 0.7139194721069637 1.554556027393044 0.1200518432684423 1.0 0.3464353191460764 6 P12235,P42345,Q9H2P0,O00584 4 +Stuttering 0.7478031226206157 1.553190689834974 0.1203775848988111 1.0 0.3469443296773427 4 P00403 1 +Abnormal lung development 0.3677704633262609 1.5524300979494552 0.1205593464279752 1.0 0.3470636943501887 47 O75844,Q6NUK1,Q8TAA9,O43683,O96000,Q99567,Q96L58,O96028,Q16134,O95202,Q9UHX1,P98175,P21964,Q14739 14 +Abdominal pain 0.3251839713367501 1.5520799068298003 0.1206431051174246 1.0 0.3470636943501887 86 P36551,O15460,Q70HW3,Q13423,P06280,O43707,Q01844,P49327,Q9UGP8,P04062,P23786,Q9Y4P3,Q9NZ08,P21912,Q14108,Q02978,P42892,Q14566,Q8N1F7,Q92621,Q12769,O14936,Q8NFH4,P35637,Q5HYI8,P01889 26 +Infantile axial hypotonia 0.6116589325832542 1.5517253112704572 0.1207279636605207 1.0 0.3470928955239971 10 P17900,P07602,Q15043 3 +Uplifted earlobe 0.6120186697783057 1.5508707740095762 0.1209326555742151 1.0 0.3472516179220047 2 Q9H9B1 1 +Hypoparathyroidism 0.5865716450499194 1.548277295186395 0.1215555484930333 1.0 0.3484010460693699 12 P03886,P00403 2 +Protruding tongue 0.5617553015981746 1.5479559215346443 0.1216329093251222 1.0 0.3484010460693699 14 Q10713,Q96RL7,Q99519 3 +Abnormality of the dorsal column of the spinal cord 0.6775605485847621 1.5442570722221844 0.1225260676349258 1.0 0.3500184039138017 3 P54886,Q8WVX9 2 +Periventricular white matter hyperintensities 0.6103081407619795 1.544201912174069 0.1225394257652223 1.0 0.3500184039138017 10 P17900,O75503,P07602 3 +Onset 0.2701247243741779 1.5440581535548326 0.1225742451932319 1.0 0.3500184039138017 399 P61916,O95630,P51798,Q70HW3,P50897,Q9H0U3,Q9UGP8,P04062,P23786,Q12768,P07602,Q99567,P16278,P49770,P43304,P28288,Q16637,Q6NUK1,P55011,P43243,Q5JRX3,P54802,Q00839,O60762,Q8NFH4,O14979,O15118,Q8TCJ2,Q5XKP0,Q9UHX1,Q8IV08,Q9NR77,Q9H490,Q9Y3A4,Q9Y320,Q7LGA3,Q8TD16,Q5JPH6,P38435,P36551,P78318,Q8WVX9,P35658,Q9P0J0,Q9H9P8,O14773,Q96KP1,P11166,P78527,Q9NWS8,Q96EK5,Q96N66,P21912,O75746,O43292,P82663,P55795,Q06787,Q96PU5,Q9Y4G8,P12235,P09001,Q9UBS4,Q9P032,Q07021,Q6ZXV5,Q04446,Q13510,O76031,O14678,Q9NP80,Q96CU9,P06865,P06280,Q99707,Q2TAA5,Q99797,Q10713,P07437,Q15067,Q9Y6M9,Q9NPL8,P31483,P61586,Q9NZJ7,P08670,Q14566,P42345,Q4J6C6,P51970,Q8TB36,P51571,O95831,O75306,Q13277,P50402,P46977,P22830,Q96EY8,Q9NVI7,O75648,Q6NUQ1,O00584,Q9BW92,Q9Y2Z2,O76024,Q15904 107 +Abnormal odontoid tissue morphology 0.3670090655673445 1.543490796373851 0.1227117388667604 1.0 0.3501957854883102 47 Q96AY3,P53701,P16278,P51648,P61586,Q96L58,Q13535,Q9Y4P3,P21964 9 +Ulnar deviation of the wrist 0.7448053817479976 1.540135088786405 0.1235274282715277 1.0 0.3518751880745052 4 P16278 1 +Neoplasm of the pituitary gland 0.5481432079277753 1.539295863471882 0.1237320833535862 1.0 0.3522421931744862 15 O75874 1 +Abnormality of the breast 0.3206254383323125 1.5386678208187563 0.1238854120865218 1.0 0.3524627217109494 114 Q7LGA3,O75874,P61978,P28340,O14678,P18074,P48735,Q07864,Q92974,Q8NI60,Q13315,Q9Y4W2,Q9UM00,O95202,Q5SRE5,P49327,Q2TAA5,P23786,Q96KP1,Q12768,P52701,Q9Y619,Q96EK5,P07437,P21912,Q15067,Q6NUK1,Q06787,Q9H2P0,Q9NXE4,Q13535,O96028,P04049,O60762,Q99496,Q5HYI8,Q9UBM7,P10586,Q96A33,Q14738 40 +Abnormality of abdominal situs 0.6751065804390628 1.532580717866729 0.1253791954302929 1.0 0.3553995112570223 3 O96028 1 +Rib segmentation abnormalities 0.6751065804390628 1.532580717866729 0.1253791954302929 1.0 0.3553995112570223 3 O96028 1 +Hypoplastic pubic rami 0.6751065804390628 1.532580717866729 0.1253791954302929 1.0 0.3553995112570223 3 O96028 1 +Craniofacial asymmetry 0.6751065804390628 1.532580717866729 0.1253791954302929 1.0 0.3553995112570223 3 O96028 1 +Achilles tendon contracture 0.5838555412173566 1.5322809473356738 0.1254531206331288 1.0 0.3553995112570223 12 Q8TD16,Q8WXH0,Q9H9S5,P50402,O60313 5 +Tracheobronchomalacia 0.6082263710618532 1.5310127679803096 0.1257662371130714 1.0 0.3556983441049716 2 Q9H9B1 1 +Psychotic mentation 0.6693358314020694 1.5264891592480034 0.126888088226043 1.0 0.3572860956958762 7 P00403 1 +Bilateral coxa valga 0.6737214446985592 1.5259870806529223 0.1270130820006936 1.0 0.3574214288160039 3 Q96A33 1 +Limb girdle muscular dystrophy 0.629352934344365 1.5244728376442584 0.1273906370895359 1.0 0.3578336758875355 8 P50402,P09651,Q8WXH0,O14979 4 +Lactose intolerance 0.6732568939332222 1.5237752201768475 0.1275648716705506 1.0 0.3581065823452437 3 Q14566 1 +Abnormal nephron morphology 0.3534143764293656 1.5222702777938146 0.1279413722241686 1.0 0.3587300032308314 67 P06280,O43707,P00403,O75306,P23786,Q9Y4P3,Q9NZ08,Q14108,P21912,Q02978,P03886,O95470,P09001,Q8N1F7,Q92621,Q12769,P52429,Q86YH6,Q04446,Q8NFH4,P01889 21 +Cutaneous cyst 0.6723081412314004 1.519257213870167 0.1286977649451182 1.0 0.3598555444859265 3 Q8TAA9,O60716 2 +Abnormality of the elbow 0.3584831673438941 1.5184624554656945 0.1288978573447046 1.0 0.3598555444859265 64 Q7LGA3,P23786,Q96AY3,P37268,P16435,P48651,Q9Y619,Q96L58,Q13535,Q6DKJ4,Q15427,Q13510,O60568 13 +Abnormality of earlobe 0.4171935689531191 1.5178075649867149 0.1290629174579125 1.0 0.3598555444859265 32 Q7LGA3,P53701,P16435,Q15392,P98175,P21964 6 +Joint laxity 0.3248668352845404 1.5171545509787865 0.129227668067019 1.0 0.3598555444859265 80 Q32P28,P55795,Q96AY3,P16278,Q06787,Q9Y619,Q9Y487,Q9UL01,Q96L58,Q9UHX1,Q9Y4P3,Q96HY6,Q96A33 13 +Paraparesis 0.4461470278122016 1.5104613596045395 0.1309257419393665 1.0 0.363543808669968 27 Q6DKK2,P35637,Q9Y619,P04062 4 +Infectious encephalitis 0.6660458936332568 1.5102154824179612 0.1309884493571946 1.0 0.363543808669968 7 Q9H9P8,Q9NZ08,Q14739,P01889 4 +Abnormal left ventricle morphology 0.4319477633336376 1.5086860719711983 0.1313790265235193 1.0 0.3640139216884518 29 Q6NUK1,P10253,O43683,Q15233,Q07021,P03886,Q9H9S5,P12235,P06280,Q9P2L0,O75880,P40939,P21912,P00403,O75431,Q96RR1 16 +Chorioretinal dysplasia 0.7040212963652692 1.5086454439344004 0.1313894143111786 1.0 0.3640139216884518 6 Q8NAT1 1 +Decreased calvarial ossification 0.7375307208636473 1.508417879914628 0.1314476097142733 1.0 0.3640139216884518 4 O75844 1 +Inguinal hernia 0.3220636568182154 1.5083255168776115 0.1314712355990577 1.0 0.3640139216884518 83 Q32P28,P51970,Q10713,O14678,P48651,P16278,Q9Y487,Q9UL01,Q99519,Q9NWM8,Q9UHX1,Q9Y4P3,P07437,P21964,P08236 15 +Hyporeflexia 0.313272441966117 1.5074363581264878 0.1316988452309486 1.0 0.3644269415979675 127 Q15120,P11177,Q8TB36,Q92974,Q13045,Q99720,P04062,O95831,O15269,Q10713,P07602,O43681,Q9NWS8,Q15067,O75648,P03886,Q06787,Q9NZJ7,P54802,P12235,P23378,Q96RL7,P35637,O14979,Q8NAT1,Q9NR77,P35610 27 +Abnormal thorax morphology 0.2897993254615612 1.503670448468967 0.1326662418744075 1.0 0.3661256484480067 243 Q7LGA3,Q8TD16,P61978,P78318,P51798,Q9UM00,Q9UBN7,O95202,Q6DKJ4,P98175,P61313,P21964,P08236,P04062,O95831,O75844,Q32P28,Q96J02,Q12768,P16278,Q9Y619,Q9Y487,P50402,Q15427,Q9Y4P3,P07437,O75477,Q9NVI7,Q8N201,P42858,O75648,P55011,P55795,Q06787,P15586,Q9UL01,Q99519,Q96L58,Q13535,Q96PU5,O96028,O75845,P54802,O75718,Q14739,P42345,Q8TAA9,Q96HY6,Q96AY3,P16435,P48651,Q6ZXV5,Q9Y366,P51648,Q9UBM7,Q96PZ0,Q9UHX1,P51812,Q96A33,Q13510,Q9H490,O60313 62 +Hemianopia 0.6252451268022508 1.502705526923847 0.1329149968630503 1.0 0.3661256484480067 8 P00403 1 +Generalized hyperkeratosis 0.7359391055950992 1.5014722123260926 0.13323346864032 1.0 0.3661256484480067 4 O75844,P21912 2 +Severe lactic acidosis 0.7357154072042768 1.5004958384909786 0.1334860106767363 1.0 0.3661256484480067 4 Q70HW3,O75648 2 +Toxemia of pregnancy 0.7191959436795357 1.5000896838739664 0.1335911728208283 1.0 0.3661256484480067 5 Q14739 1 +Unusual infection by anatomical site 0.5783530257348798 1.4998339703541828 0.1336574154144267 1.0 0.3661256484480067 12 Q9H9P8,Q8TAA9,O15460,P01889,Q9NZ08,Q14739 6 +Vertebral segmentation defect 0.419549097240051 1.4997646486728125 0.1336753775755053 1.0 0.3661256484480067 31 P61978,Q8TAA9,P16435,Q9Y619,O96028,O95202,Q6DKJ4,Q9Y4P3,Q9UHX1 9 +Abnormal acetabulum morphology 0.4696440781907853 1.4995239088996395 0.1337377709280311 1.0 0.3661256484480067 23 Q96AY3,P16278,Q96L58,Q9Y584,O75718,P08236 6 +Shuffling gait 0.6130405184723956 1.4960601776513869 0.1346379740679824 1.0 0.3662551192372335 9 P04062 1 +Cerebellar atrophy 0.309708737753952 1.4955804259622607 0.1347630271279907 1.0 0.3662551192372335 144 P51970,P51798,Q96CU9,Q8WVX9,P35658,O14773,Q10713,P46977,P07437,Q9NVI7,Q14108,Q96D71,Q15043,P04350,P42858,O43292,O75648,Q06787,Q6DKK2,P13073,O75845,Q5JRX3,P12235,O60762,O14936,O75503,Q9BT22,Q8TCJ2,Q5XKP0,Q03154,Q8IV08,Q9H490,O60313,Q9Y320 34 +Insidious onset 0.718099969957337 1.4951572161668518 0.1348734163748433 1.0 0.3662551192372335 5 Q9NR77,O60313,P04062 3 +Temporal pattern 0.6234740230465069 1.4933135412200975 0.1353551326263544 1.0 0.3666464272904242 8 Q9NR77,O60313,Q12768,P04062 4 +Redundant skin 0.4630311990653747 1.4930624138467117 0.1354208500280602 1.0 0.3666464272904242 24 Q6NUK1,Q15022,O96000,P48651,P38435,Q9Y487,Q9UL01,Q9Y4P3 8 +Coarse facial features 0.345349977932992 1.4910788785427271 0.1359407869396731 1.0 0.3672387181061387 70 Q7LGA3,P10619,P61978,P16278,Q06787,P15586,Q99519,P06280,P54802,Q9Y4P3,Q96A33,P08236,P38159 13 +Lacticaciduria 0.7335452820096082 1.4910217338514231 0.1359557888813083 1.0 0.3672387181061387 4 P03886 1 +Generalized onset motor seizure 0.3587231547326716 1.4898102610616255 0.1362741323465794 1.0 0.367493608856856 59 P07602,P03886,P16278,Q9Y619,Q9NZJ7,Q13510,Q96N66,P04062 8 +Aplasia hypoplasia of the vagina 0.6658885322439536 1.4886622563855658 0.1365763287193964 1.0 0.367493608856856 3 P51809,P30153 2 +Urogenital sinus anomaly 0.6658885322439534 1.4886622563855645 0.1365763287193968 1.0 0.367493608856856 3 O14974,P51809 2 +Abnormal lumbar spine morphology 0.576434611785328 1.488509507868399 0.1366165766091789 1.0 0.367493608856856 12 Q99575,O75845,P51812,P08236,P04062 5 +Gingival bleeding 0.5884087684944196 1.487495807457515 0.1368839097054559 1.0 0.3678210783641112 11 P04062 1 +Abnormal shape of the frontal region 0.3148585982128156 1.4856519997494124 0.1373711931386878 1.0 0.3686495270310359 121 P51798,Q13045,Q9UBN7,O95202,Q6DKJ4,Q15392,O43683,Q12768,P16278,Q9Y619,Q9Y487,Q9NVI7,Q8N201,Q15067,Q06787,O15360,P15586,Q9UL01,Q99519,Q96L58,P13073,O96028,Q14739,P42345,Q00839,P16435,P48651,Q6PGP7,Q9Y366,Q4J6C6,P51812,Q14738 32 +Venous insufficiency 0.7158707859867961 1.4851213975015292 0.1375116688383211 1.0 0.3686495270310359 5 P04062 1 +Varicose veins 0.7158707859867961 1.4851213975015292 0.1375116688383211 1.0 0.3686495270310359 5 P04062 1 +Aplasia hypoplasia involving the skeleton 0.2651526397812953 1.4828283978916614 0.1381200090443983 1.0 0.3692206916112053 328 Q7LGA3,Q8TD16,O75874,O14678,P38435,P48735,O95630,P51798,P51571,Q13045,Q9Y4W2,Q9UM00,O95202,Q6DKJ4,Q15392,Q9UBN7,P98175,P21964,P08236,P04062,Q86XL3,O75844,O95831,Q32P28,Q15022,O43683,Q12768,P37268,P53701,Q99567,P16278,Q9Y619,O15228,Q15427,Q9Y4P3,P07437,Q9NVI7,Q8N201,Q6NUK1,P42858,O75648,P55795,Q6NUQ1,P55011,Q06787,O15360,Q9UL01,Q96L58,Q13535,P13073,Q96PU5,O96028,O75845,O75718,Q16625,Q14739,P42345,Q8TAA9,Q00839,Q96AY3,P16435,P48651,O60762,O14936,Q9Y366,P51812,Q9UBM7,Q9BT22,Q96PZ0,Q96MF7,Q9UHX1,Q96HY6,Q96A33,Q13510 74 +Neoplasm of the adrenal gland 0.5625727019626714 1.4806021991834288 0.1387126090093891 1.0 0.3705915937076606 13 O75874 1 +Corneal erosion 0.7137242235682019 1.475453475783196 0.1400906674922486 1.0 0.3740581845798777 5 P01889,P51648 2 +Abnormality of the metaphysis 0.3586734770987634 1.4747728626079588 0.1402736194073368 1.0 0.3743315541450241 56 Q9UG56,O75874,P48651,P48735,P16278,P51798,Q96L58,Q13126,Q96HY6,Q96MF7,Q14739,O95831 12 +Akinesia 0.5858845307794612 1.4730009689279686 0.1407507745142899 1.0 0.3749587720145592 11 Q99567,P04062 2 +Exaggerated cupid s bow 0.6962204219308393 1.472392844428429 0.1409148243414588 1.0 0.3751806727165718 6 P61978,Q00839,Q6DKJ4 3 +Progressive spasticity 0.5250562521164599 1.469681109988192 0.1416481411626202 1.0 0.3769171041474992 16 P17900,P07602,Q9NZJ7,O43681,O60313 5 +Clonus 0.4022507213769137 1.4685834402193196 0.1419458091426875 1.0 0.3770613089061899 35 P42858,Q12768,P07602,P35637,Q9Y619,Q9NZJ7,Q99720,Q9BQT8,Q15043 9 +Death in infancy 0.3555481238479964 1.4664387639429248 0.1425287923318934 1.0 0.3781774809674339 62 Q6NUK1,Q12768,P07602,Q15904,Q13277,P16278,Q9NZJ7,Q9BT22,P51114,Q6DKJ4,Q9NWS8,O75718,P23378,P04062,Q15067 15 +Abnormal talus morphology 0.4989812406954559 1.4660806761930911 0.1426263094504747 1.0 0.3782202247185534 18 O75844,P16435,Q99567,Q9UPT5,Q9NXE4,Q9UHX1,P98175 7 +Abnormal sensory nerve conduction velocity 0.6944575978793892 1.4641927962543542 0.1431412779550505 1.0 0.3788582341067414 6 Q9NR77 1 +Intestinal pseudo obstruction 0.5959400837073086 1.464003170667247 0.1431930820257076 1.0 0.3788582341067414 10 P03886,P61978,P00403 3 +Fetal akinesia sequence 0.7108263490418094 1.46239562495688 0.1436328276454261 1.0 0.3789701587084823 5 P04062 1 +Hypoplasia of the iris 0.6940057491351512 1.462090515808102 0.1437164073590602 1.0 0.3789701587084823 6 Q7LGA3,O96028 2 +Hemivertebrae 0.5718949449039911 1.4616884462791968 0.143826604754188 1.0 0.3789701587084823 12 Q9Y619,Q12768,Q9UHX1,P16435 4 +Paralysis 0.3598651460616708 1.461443162827658 0.1438938627451771 1.0 0.3789701587084823 49 P17900,Q8TB36,P11166,P36551,P43243,Q15165,P51798,P35637,P50402,P10253,Q9NR77,P21912,P04062,Q92804 14 +Abnormal epidermal morphology 0.4982414651924174 1.4608509782323351 0.1440563422201255 1.0 0.3789840124318818 18 O75844,Q06136,P16615 3 +Generalized abnormality of skin 0.2886549484208567 1.4585490314497105 0.1446892706280289 1.0 0.3799564010631263 236 Q06136,P61916,P38435,P36551,P05091,P51798,Q13315,P06280,Q16134,P98175,P21964,P00403,P04062,O75844,O75306,O15269,P37268,P53701,P11166,Q5T2R2,P16278,O15270,Q9Y487,P49257,P28288,Q9NWM8,Q9UJS0,Q15427,Q9Y4P3,P22830,Q6YHK3,Q14108,P21912,Q6NUK1,O75648,Q6NUQ1,P03886,O15360,P00374,Q9UL01,Q99519,Q96L58,Q13535,Q00325,O43772,Q16625,Q8IZA0,Q14739,P10619,O60762,O14936,P48651,Q6PGP7,P51648,Q9UBM7,Q14376,O15118,Q15904,P01889,Q13126,Q5HYI8,P51812,O76031,O60568 64 +Neurodegeneration 0.4332551813218726 1.4578952920441373 0.1448694065234375 1.0 0.3799572057188273 28 P17900,Q15165,P35637,Q6DKK2,Q92804 5 +Breast carcinoma 0.4641949730694378 1.4566987251356978 0.1451995618580601 1.0 0.3799572057188273 23 O75874,P48735,Q5HYI8,Q07864,Q13315,Q13535,P21912 7 +Short middle phalanx of finger 0.7256275539988111 1.456423469886548 0.1452755914309373 1.0 0.3799572057188273 4 Q8IWS0,Q9UHX1,Q03164 3 +Generalized joint laxity 0.5352432159970164 1.4563435091767467 0.145297683476179 1.0 0.3799572057188273 15 Q9UHX1,Q9UL01 2 +Paroxysmal involuntary eye movements 0.4738082710754466 1.449041252077664 0.1473260626343671 1.0 0.3844023228319445 21 Q9Y6M9,Q9NPL8,Q86Y39,P03886,Q96CU9,O43676 6 +Hamartoma 0.5093439587803106 1.4484270344611998 0.1474976585946417 1.0 0.3844023228319445 17 O75874 1 +Agenesis of corpus callosum 0.3187319805945421 1.4477465893929893 0.147687935052738 1.0 0.3844023228319445 92 Q7LGA3,P61978,P11177,O95202,Q15392,P00403,Q86XL3,P23786,Q15022,Q10713,P53701,P42695,P55011,P03886,O96028,P23378,P48651,Q8NAT1,Q9UHX1 19 +Dysdiadochokinesis 0.5216299008022086 1.4469385693153194 0.1479141295672881 1.0 0.3844961878595549 16 Q6DKK2,O75503,Q06787 3 +Hyperkeratosis 0.3544738283168835 1.4420983735255282 0.1492746238450832 1.0 0.3872305429281166 60 O75844,Q06136,O15269,O15270,P51648,P16615,P06280,Q9NWM8,P04062 9 +Hepatic encephalopathy 0.7218871988131677 1.4400630452474945 0.1498495631212615 1.0 0.388204598266427 4 Q9UJS0,Q6NUQ1 2 +Resting tremor 0.5080321590519709 1.439440068535543 0.1500258787139421 1.0 0.388204598266427 17 P07602,Q06787,Q9NZJ7,P12235,P04062 5 +Xerostomia 0.5443033915104081 1.438891749919353 0.1501811953642176 1.0 0.388204598266427 14 P55011,Q15165,P35637,Q14739,Q92804 5 +Abnormal thalamic size 0.7214959287472316 1.4383510640750412 0.1503344699972999 1.0 0.388204598266427 4 P11166,Q9UPT5 2 +Chordee 0.6887421425578631 1.4375884193477175 0.1505508686846253 1.0 0.388204598266427 6 P53701,P16435 2 +Falls 0.6128875270809753 1.4370953071246058 0.1506909145002415 1.0 0.3883028223894188 8 P21912,Q9BQT8,Q96RL7,Q8WVX9 4 +Occipital encephalocele 0.6880275098490104 1.4342600951454725 0.1514980533882464 1.0 0.3901662727504394 6 Q6ZXV5,Q10713,O43505 3 +Bruxism 0.612073775525747 1.4327688207267435 0.1519239144906912 1.0 0.3910462641128816 8 P61978,Q96RL7 2 +Fasting hyperinsulinemia 0.7188729214627928 1.4268716483411532 0.153616894319315 1.0 0.393946288595994 4 Q16836,P00367 2 +Mild postnatal growth retardation 0.5883897316219482 1.426857094865742 0.1536210900500005 1.0 0.393946288595994 2 P10644 1 +Progressive hearing impairment 0.553402943621842 1.4247589990577492 0.1542268779941475 1.0 0.3947868182704185 13 P03886,O60313,P00403 3 +Impaired proprioception 0.3906053174084025 1.42422637619963 0.1543809519224923 1.0 0.3949636027708697 37 O14773,Q96RL7,Q06787,Q9Y619,P54802,Q8TAF3,Q9NR77,Q8IV08 8 +Acute coronary syndrome 0.4797031709018372 1.4222706382424084 0.1549476992234599 1.0 0.3960964966034127 19 O75844,Q9NZ08,P06280,Q9Y4P3 4 +Raynaud phenomenon 0.6099290774231094 1.4213628671838483 0.1552112957042426 1.0 0.3960964966034127 8 O75844 1 +Wide anterior fontanel 0.4701171614926612 1.4210495700107002 0.1553023492063254 1.0 0.3960964966034127 21 P42345,Q32P28,P16435,Q9Y487,Q16134,O75718,Q14738 7 +Shallow orbits 0.599268522651116 1.4210295632234768 0.155308165152582 1.0 0.3960964966034127 9 O75844,O60568 2 +Laryngomalacia 0.5049791041003237 1.4185110525421645 0.1560416141474738 1.0 0.3970259251528826 17 P21964,P07602,P16435 3 +Motor axonal neuropathy 0.4744552119721371 1.4173188385401163 0.1563897297703502 1.0 0.3976938612550889 20 O15269,O15270,P22626,Q8TAF3,O60313 5 +Delayed epiphyseal ossification 0.7005906984126111 1.4162225755515256 0.1567103481192182 1.0 0.3980485245350451 5 Q96L58,Q96HY6 2 +Telangiectasia 0.3854205257528117 1.4159308810745077 0.1567957423841868 1.0 0.3980485245350451 38 P10619,P03886,Q99519,Q13315,Q13535,P06280,Q8IZA0,Q14739 8 +Abnormal auditory evoked potentials 0.598242431452946 1.4154307137993054 0.1569422496745196 1.0 0.3980485245350451 9 Q9NZJ7,P07602 2 +Emg abnormality 0.322883510357655 1.4153784119232862 0.1569575757529493 1.0 0.3980485245350451 78 O14773,O15269,Q15120,P07602,P31483,Q96RL7,Q8TB36,O15270,P13473,Q9NZJ7,P51114,P22626,P12235,Q13510,Q9NR77,O60313 16 +Renal tubular dysfunction 0.3661770234651321 1.413790857546606 0.1574233187116964 1.0 0.398794295929412 42 Q9Y6M9,Q9NPL8,Q86Y39,P03886,Q96CU9,O43676,Q9NWS8,P00403 8 +Severely reduced visual acuity 0.6501313101838254 1.4134068669510402 0.1575361276801405 1.0 0.3988625881209445 3 O15078,Q13277 2 +Poor motor coordination 0.5284841264326058 1.412756022788918 0.157727472915472 1.0 0.3991295420290213 15 O75503,Q10713,Q96RL7,Q06787 4 +Movement abnormality of the tongue 0.7151535737848329 1.410586825404214 0.1583664785336735 1.0 0.4003104783827244 4 P10253 1 +Vitritis 0.6492245988601033 1.4090706359865324 0.1588142825714773 1.0 0.4012241200799802 3 P53701 1 +Increased total bilirubin 0.7146165047541722 1.4082346437210602 0.1590616010535948 1.0 0.4016305426603268 4 P23786 1 +Cerebral palsy 0.5743684440733617 1.4067628694388563 0.1594977162008324 1.0 0.4025129763547351 11 O75874,P48735 2 +Abnormal conjugate eye movement 0.2625043780405633 1.4059145518884943 0.1597494996596191 1.0 0.4026227898471828 328 Q7LGA3,P61916,P38435,Q9H061,Q96CU9,Q7KZN9,Q92974,Q13315,P51571,O43676,Q15907,Q15392,O95202,Q6DKJ4,Q99720,P21964,Q9P0J0,P04062,Q2TAA5,O75306,Q10713,P07602,Q86Y39,Q9Y619,Q9Y487,Q9Y4P3,Q9NVI7,Q8N201,Q15067,P42858,Q9Y6M9,Q9NPL8,P55795,O75648,P03886,Q06787,O15360,P61586,Q9NZJ7,Q9UL01,Q99519,Q13535,Q96PU5,O96028,O95470,P12235,Q14739,P42345,Q96RL7,P16435,P35637,Q9BT22,O15118,Q96PZ0,Q9UHX1,O60313,Q14738 57 +Leukoencephalopathy 0.3157719453435991 1.4056154814818176 0.1598383363753011 1.0 0.4026227898471828 99 P11177,Q96CU9,P51571,O43676,O95202,O95831,O75306,P07602,Q86Y39,P49770,P17900,Q9Y6M9,Q9NPL8,O75648,P03886,Q9NZJ7,O96028,O00584,O75503,Q9UHX1,O60313 21 +Facial hypotonia 0.5499857147378462 1.403916975943626 0.1603435739350076 1.0 0.4031148509210203 13 Q14738,Q15907,Q9UL01 3 +Nephropathy 0.4573770814855367 1.4029985177843445 0.1606172809396495 1.0 0.4035845793648522 23 P03886,P06280,Q14108,P00403 4 +Narrow forehead 0.3548417108682211 1.401481485097105 0.1610701403639085 1.0 0.4045037146652536 49 Q7LGA3,O43292,P55011,Q9UBM7,Q9NXE4,Q9UM00,O75845,Q9UHX1,Q96A33,Q9H490,Q14738 11 +Type i diabetes mellitus 0.5615532287591996 1.4004783104070904 0.1613701340089031 1.0 0.4046040374581038 12 P00403 1 +Proximal upper limb amyotrophy 0.6439196900546613 1.4004742547054532 0.1613713476990672 1.0 0.4046040374581038 7 O14979 1 +Abnormality of the musculature of the upper arm 0.6439196900546613 1.4004742547054532 0.1613713476990672 1.0 0.4046040374581038 7 O14979 1 +Chromosomal breakage induced by crosslinking agents 0.7122411416592764 1.3978294251592789 0.1621642958922184 1.0 0.4063728795659369 4 P13073 1 +Emphysema 0.5727103172843262 1.39721246773727 0.1623496885922173 1.0 0.4065548189474491 11 Q03518,Q03519 2 +Spastic gait 0.445258161517035 1.3970055167070647 0.1624119121753047 1.0 0.4065548189474491 25 P49902,Q12768,Q9Y619,Q15041,Q8WVX9,Q8TAF3,O75477,Q9NVI7,P54886,Q15043 10 +Stenosis of the external auditory canal 0.6426484187035738 1.3941559227428406 0.1632705249118524 1.0 0.4078251928712185 7 O96028,O95202,P16435 3 +Abnormal larynx physiology 0.5370395918618507 1.3933458492334558 0.1635152322364343 1.0 0.4082169634446395 14 Q15165,P35637,Q92804 3 +Steroid resistant nephrotic syndrome 0.6952017909692663 1.3918850958520788 0.1639571957808354 1.0 0.4091005003210319 5 Q92621,Q12769,Q8N1F7 3 +Abnormal number of granulocyte precursors 0.5813885647608052 1.3900047137390743 0.1645274459784738 1.0 0.4103030134277988 2 O75533 1 +Diminished motivation 0.4442918854235081 1.3890710708183716 0.1648111396280782 1.0 0.4107899971631177 25 P17900,Q96RL7,Q06787,P35637,P06865,P35610,P04062 7 +Chronic otitis media 0.418437077610002 1.3877552624696805 0.1652115819028474 1.0 0.4113467360775077 29 Q06787,O96028,O95202,Q6DKJ4,Q9Y4P3,Q03519,Q03518,P21964 8 +Abnormality of the musculature of the thigh 0.6031842052336073 1.3854643438491907 0.1659105280079817 1.0 0.4115896245684216 8 O14979 1 +Abnormality of the musculature of the lower limbs 0.4247530928372917 1.383451611880771 0.1665264344808941 1.0 0.4115896245684216 28 Q12768,Q96RL7,O14979,P50402,Q8NAT1,Q9NR77 6 +Generalized hypotonia 0.2625878276756944 1.382700578249601 0.1667566945393357 1.0 0.4115896245684216 370 P11177,P61916,O95630,P51798,Q9UBX3,Q7KZN9,Q92974,Q70HW3,O43676,P50897,Q8N511,P23786,Q15022,Q12768,P07602,Q9Y619,P49770,O43681,Q96D71,Q6NUK1,P17900,P55011,P00374,O95470,Q00839,O60762,Q9UBM7,O15118,Q8TCJ2,Q8NAT1,Q5XKP0,Q13885,Q9UHX1,Q03154,P51812,Q16836,Q9NR77,O14949,Q9P0J0,Q86Y39,Q9Y487,Q9NWS8,Q96N66,O43292,P12235,Q6P4A7,Q14738,O14678,Q9NP80,Q96CU9,P06865,Q15907,Q99707,P98175,Q99797,Q10713,Q9BWD1,O15228,P10253,P07437,Q9Y6M9,Q9NZJ7,Q99519,Q96L58,P13073,O96028,P42345,P48651,P14854,P11117,Q4J6C6,Q96A33,P61978,P51571,O95202,O95831,P46977,Q96EY8,Q9NVI7,O75648,O75845,O43772,P23378,Q9BW92,Q9Y2Z2,Q14376,Q9BT22,Q96PZ0 88 +Abnormality of limb epiphysis morphology 0.3999698808164684 1.3825545814915616 0.1668014835831639 1.0 0.4115896245684216 33 Q7LGA3,Q6NUQ1,P16435,Q9Y366,Q96L58,Q13535,O15228,O96028,O95202,O60568,O95831 11 +Abnormal circulating carbohydrate concentration 0.3678306824626217 1.377140557652061 0.1684687954821886 1.0 0.4139111707087511 41 Q9Y6M9,Q9NPL8,Q9NP80,Q86Y39,P03886,Q96CU9,Q70HW3,Q9BWD1,O43676,Q5JRX3,O95831 11 +Furrowed tongue 0.6917987183218969 1.3765076025525864 0.1686645352134892 1.0 0.413933697992619 5 P61978,P21912 2 +Chorioretinal coloboma 0.6388777848852376 1.3754089032131152 0.1690047103103997 1.0 0.413933697992619 7 Q10713,Q12768,O14936,O15078,Q9P2D1 5 +Peripheral neuropathy 0.2935417163303333 1.3751456949829852 0.1690862802081405 1.0 0.413933697992619 175 Q15120,Q8TB36,Q96CU9,O15460,Q9Y2R0,Q8TAF3,P00403,Q9P0J0,O95831,O75306,O15269,Q10713,P07602,O15270,Q9NWS8,Q15067,Q9NPL8,P03886,Q06787,Q9NZJ7,O95470,P54802,P12235,P22626,Q96RL7,P01889,Q8IV08,Q9NR77,O60313 29 +Glioma 0.5452172136184235 1.3748088245056451 0.1691907215858767 1.0 0.413933697992619 13 O75874 1 +Limb undergrowth 0.3491399565637557 1.3739944150462648 0.1694434162823126 1.0 0.4143337431829602 60 P42345,O75874,Q96HY6,P48735,Q13535,O15228,Q6DKJ4,Q15392,Q15427,O75718,P98175,Q9UHX1,Q14739 13 +Recurrent bronchitis 0.6384585507375125 1.3733239566003048 0.1696516582293612 1.0 0.4146247260040043 7 Q13315,Q03518,Q03519 3 +Bradykinesia 0.4478691323327198 1.371278208204683 0.170288246211292 1.0 0.4153066624134712 24 Q96RL7,Q06787,Q6DKK2,O75569,P12235,P04062,Q15043 7 +Abnormality of the biliary system 0.30856001493944 1.3693463319309285 0.1708910416484581 1.0 0.4160192122556279 120 P61916,Q5JPH6,P36551,Q16134,O95202,P21964,P04062,Q96J02,Q10713,P07602,P11166,P28288,O43681,Q9UJW0,P22830,Q9Y4P3,P09601,Q14108,O75648,Q6NUQ1,P00374,Q9NZJ7,O75845,O96028,Q16625,Q14739,Q6PGP7,O14936,Q15904,Q5HYI8,Q14376,Q9UBM7,O15118,Q5XKP0,Q96A33,Q13510 36 +Global brain atrophy 0.4679683366521133 1.3689215652509923 0.1710237939236805 1.0 0.4160192122556279 20 Q9NZJ7,Q9UHX1,P35637,P07602 4 +Extrapyramidal dyskinesia 0.6408312775997291 1.3689067104898385 0.171028437877498 1.0 0.4160192122556279 3 P35610 1 +Short nose 0.3119052372190676 1.3686213259107205 0.1711176742618392 1.0 0.4160192122556279 109 P38435,O95630,Q8WVX9,Q13045,Q9UM00,Q6DKJ4,Q15392,P04062,O75844,Q12768,Q9Y487,Q9Y4P3,Q9NVI7,Q8N201,Q6NUK1,P42892,Q9UL01,Q96L58,O75845,P42345,P16435,O14936,Q9UHX1,Q9H490,O60568,Q14738 26 +Abnormality of toe 0.2884697730519413 1.367562433770053 0.1714490820092284 1.0 0.4161715961415232 184 Q7LGA3,P61978,Q8TB36,Q13045,O95202,Q15907,Q6DKJ4,Q99720,P21964,P04062,O75844,P23786,P49902,Q15022,Q10713,P37268,Q15427,Q9Y4P3,Q8N201,P42858,O75648,P55011,O15360,P61586,Q96L58,Q13535,P13073,Q96PU5,O96028,O75845,Q14739,O60762,O14936,Q9Y366,Q9UBM7,Q96PZ0,Q9UHX1,Q96A33,Q13510,Q9NR77,Q14738 41 +Ectopia pupillae 0.6896672400082582 1.36687309225022 0.1716650873820779 1.0 0.4164339800913731 5 O96028,P61586 2 +Muscle fibrillation 0.4968784623777303 1.3629012062839494 0.1729136485040063 1.0 0.4184150057029237 17 P51114,Q9NWS8,Q13510,Q9BQT8,O95831 5 +Infantile muscular hypotonia 0.3298544046238018 1.358798103645983 0.1742105744168147 1.0 0.4208956467709419 73 Q15043,P17900,P07602,P03886,P16278,Q9Y487,Q9NZJ7,P10253,Q13510,Q2TAA5 10 +Hypoplastic vertebral bodies 0.6349688238261678 1.3559646539981425 0.1751104144715245 1.0 0.4228497846334215 7 P16278,Q6NUQ1,Q14739 3 +Epistaxis 0.5309978980312081 1.3554097030421817 0.1752870599075664 1.0 0.4230564573145733 14 P38435,P01889,P04062 3 +Progressive visual field defects 0.5746791131855431 1.3546561854254426 0.1755271235163511 1.0 0.4232747468268871 2 P35222 1 +Segmental peripheral demyelination remyelination 0.6862746628829591 1.3515340301629422 0.1765244265118712 1.0 0.4251594015418113 5 P03886 1 +Hypotension 0.4336700656323119 1.3506449374075369 0.1768091985075164 1.0 0.4256246301895965 26 P07602,Q06787,Q9NZJ7,Q13423,O43772,P35610,P04062 7 +Abnormal upper limb bone morphology 0.3105352503148111 1.3496329601512782 0.1771337461902458 1.0 0.4261850775763242 110 Q7LGA3,P51798,O95202,Q6DKJ4,P98175,P08236,O75844,Q32P28,Q15022,P16278,O15228,Q15427,Q9Y4P3,Q6NUK1,P42858,O75648,P55011,O15360,Q96L58,Q13535,O96028,Q14739,Q96AY3,P16435,P48651,Q9Y366,Q9UBM7,Q96PZ0,Q9UHX1 29 +Abnormally large globe 0.5861112115935112 1.3491646347178026 0.1772840913209539 1.0 0.4262071532625142 9 P30533,O14936,Q9H9S5,Q13535 4 +Abnormal urine protein level 0.3437471497594212 1.3471392267934532 0.1779353965383538 1.0 0.4272288642466109 65 P52429,P03886,P06280,O95470,Q9Y4P3,P09601,Q14108,P00403,P04062 9 +Pace of progression 0.2939714139915615 1.3467879153607072 0.1780485478906641 1.0 0.4272345277503652 171 Q15120,Q8TB36,Q9NP80,Q99720,Q9P0J0,P04062,O95831,O14773,Q10713,Q12768,P50402,P28288,O75477,Q14108,Q16637,Q96D71,Q15043,P04350,Q9Y6M9,P31483,P15586,O95470,P54802,P12235,O75569,Q8N1F7,O00584,Q12769,P52429,P05023,Q96RL7,O60762,O14979,Q13126,P27544,Q8IV08,Q13510,Q9NR77,O60313 39 +Bifid tongue 0.6849635036496095 1.3456045344213057 0.1784300885338492 1.0 0.4276671722867157 5 Q9P2L0,P61978,Q9UBM7,Q6DKJ4 4 +Extra axial cerebrospinal fluid accumulation 0.5729288214702575 1.3454308175927143 0.1784861487438531 1.0 0.4276671722867157 2 Q03252 1 +Simple febrile seizure 0.6358330901663205 1.3449720450971243 0.1786342623582173 1.0 0.4278014344929267 3 P11166,Q9UDR5 2 +Early onset of sexual maturation 0.3499190373820544 1.3440654155908174 0.1789272344196468 1.0 0.4282822932064293 50 Q7LGA3,P42858,O75874,O75648,P55011,O14936,P48735,Q13045,Q13423,Q96PZ0,O96028,O95202,Q9Y4P3 13 +Periventricular cysts 0.6324350196550461 1.3433562867279367 0.1791566342583326 1.0 0.4284546041749926 7 O96028,O95202 2 +Abnormal nerve conduction velocity 0.3499752628626633 1.3432727805909512 0.1791836624864422 1.0 0.4284546041749926 46 O15269,Q15120,P07602,Q8TB36,Q9Y619,Q9NZJ7,Q99519,Q99720,Q9NR77 9 +Rigidity 0.3479708370643994 1.3414108963568958 0.1797870817435356 1.0 0.4291617353818794 56 P04350,P07602,P16278,Q96CU9,Q06787,Q9NZJ7,Q15392,P12235,Q9Y287,P04062 10 +Abnormal brain lactate level by mrs 0.5629984147753772 1.3412204751631676 0.1798488804968832 1.0 0.4291617353818794 11 P03886,P00403 2 +Hypoplasia of the odontoid process 0.6679268824223011 1.3405072369930957 0.1800804930921682 1.0 0.4294938249005203 6 P36776,P16278,P08236,O95831 4 +Abnormality of lens shape 0.5717619603267335 1.339279812886405 0.1804795980355917 1.0 0.4300841635332103 2 P11047 1 +Abnormal peripheral myelination 0.373574143072723 1.3384390886018764 0.180753343885285 1.0 0.4304356923070397 39 O15269,Q96RL7,P07602,P03886,Q9NZJ7,Q9NR77 6 +Broad phalanx of the toes 0.6670432585798938 1.336381040362783 0.1814247601451901 1.0 0.4312887823867058 6 Q7LGA3,Q6DKJ4 2 +Migraine 0.4489160472888598 1.3362030835611949 0.1814829034795544 1.0 0.4312887823867058 23 P03886,P05067,P01889,P12235,Q9NZ08,P00403 6 +Abnormal cranial nerve physiology 0.3238367052184021 1.331941660601002 0.1828793597931064 1.0 0.4334987273463125 75 O75874,P07602,P48651,P48735,Q9NZJ7,Q9UHX1,P12235,Q9NZ08,Q13510,Q9NR77,Q15043 11 +Oval face 0.6299870791751323 1.3311722263827048 0.1831323478250088 1.0 0.4338770464023412 7 Q96L58,O14936,Q9UHX1 3 +Congenital contracture 0.3487203083896459 1.330007802788822 0.1835157004554821 1.0 0.4341098711051949 45 O75844,Q99567,P04062,Q15392 4 +Hyperconvex fingernails 0.6654344318873527 1.3288676651322509 0.1838916333404976 1.0 0.4342311033269246 6 P48651,O96028,O95202 3 +Shoulder girdle muscle weakness 0.5267531788513762 1.3287331215425928 0.1839360334368032 1.0 0.4342311033269246 14 Q8TD16,P46976,P07602,P43243,Q9H9S5,Q9NZJ7,O14979,P12235 8 +Somatic sensory dysfunction 0.3091769906664987 1.3268648279494968 0.18455340094006 1.0 0.4352462440444257 110 P61978,Q15120,Q8TB36,O15460,P06280,Q8TAF3,O14773,O15269,P07602,O15270,Q9Y619,Q9NZ08,Q06787,P05067,Q9NZJ7,Q9UL01,P54802,Q96RL7,P01889,Q8IV08,Q9NR77 21 +Diarrhea 0.3146369094437025 1.326163204467522 0.1847856443157618 1.0 0.4353519794579257 79 P36551,Q13423,P06280,P00403,Q96J02,Q13277,Q9UJS0,P42892,P03886,P15586,P54802,Q14566,O60762,Q6PGP7,Q15904,Q5HYI8,Q9BT22,P01889,Q16836,Q96A33,Q13510,P35610,Q14738 23 +Abnormality of the septum pellucidum 0.3480098088529386 1.323942102665115 0.185522273920657 1.0 0.4368659324051558 44 P53701,P48651,P51571,Q8NAT1,O96028,Q15392,Q96N66,Q14738 8 +Abnormal ciliary body morphology 0.6311642836300069 1.3226060347170658 0.1859664263375893 1.0 0.4374683629187038 3 Q99496,O75533 2 +Cystic liver disease 0.6636169471685702 1.3203787654304715 0.186708589636861 1.0 0.4385480826354176 6 Q9UBS4,Q9UGP8,O43909 3 +Abnormality of the gallbladder 0.3715075430916109 1.3165175703785457 0.188000385064097 1.0 0.4409135734516883 39 P07602,Q9NZJ7,O75845,O43681,O95202,P22830,Q9Y4P3,O96028,Q96A33,P21964,P04062 11 +Atrophy degeneration affecting the central nervous system 0.2622503186446261 1.3155372969794008 0.1883293910961285 1.0 0.4412397130774651 320 Q7LGA3,Q8TD16,P51970,O14678,O95630,Q15165,Q8WVX9,Q9UM00,P50897,Q99707,Q99720,P08236,P00403,P04062,Q2TAA5,O95831,O75306,O14773,P35658,Q10713,Q12768,P07602,Q9H9P8,Q86Y39,P11166,P16278,Q9Y619,Q9UPT5,Q9NWS8,Q9Y4P3,Q96N66,Q16637,Q96D71,Q15043,P42858,P17900,O75648,P55011,P31483,P03886,P43243,Q06787,P00374,P05067,Q9NZJ7,Q9UL01,Q6DKK2,P13073,O75845,Q5JRX3,P22626,Q16625,Q92804,O76024,Q96RL7,O60762,O14936,O75503,P35637,Q9BT22,O15118,Q96PZ0,Q9UHX1,Q03154,P51812,Q96A33,Q13510,Q9H490,O60313,Q9Y320,Q9NZ01 71 +Broad ribs 0.6933714710657952 1.315082538500329 0.1884821643813616 1.0 0.4413353909804264 4 P16278 1 +Gonadal neoplasm 0.4232687798749304 1.3145677761466383 0.1886552058732515 1.0 0.4413353909804264 27 O75874,P48735,Q13423 3 +Prominent superficial blood vessels 0.5465281569407413 1.3113380134884831 0.1897435908927507 1.0 0.4434349714726961 12 O75844,P48651,Q9Y487 3 +Abnormality of the knee 0.3099101753467368 1.3081480991863874 0.1908230818193614 1.0 0.4452858051897305 96 Q7LGA3,P23786,P49902,Q96AY3,P37268,P48651,Q6ZXV5,P16278,Q9Y619,P21964,Q96L58,Q96PU5,Q9Y4P3,Q96HY6,Q13510,Q9NR77,P08236,Q86XL3 18 +Functional abnormality of the inner ear 0.2783197531503785 1.303228324299798 0.1924968228844146 1.0 0.4485156665601756 263 Q7LGA3,P61978,Q15120,Q9NP80,P78318,Q9H061,Q96CU9,O15460,Q8WVX9,P06280,O43676,O95202,P00403,P04062,Q2TAA5,O75844,O95831,O15269,O75306,P07602,Q86Y39,P78527,Q9NWM8,O43681,Q9Y4P3,Q9NZ08,Q9NR28,Q6YHK3,P21912,Q15067,Q15043,P51572,Q9Y6M9,P55011,Q02978,P42892,Q9NPL8,P03886,Q9NZJ7,Q99519,Q96L58,O96028,O95470,P12235,O00584,Q6P2Q9,P38159,Q9UG56,Q9P032,O76024,O96000,Q07021,O14936,P48651,P40855,P35637,Q9UBM7,Q15904,Q14376,P01889,Q96PZ0,Q5XKP0,Q03154,P51812,Q13510,Q9NR77,O60313 67 +Abnormal cerebral vascular morphology 0.325760455797158 1.3006024646047163 0.1933945630011901 1.0 0.4500098956121864 73 O75844,P23786,P38435,P03886,P05067,Q96L58,O60568,P06280,Q9Y4P3,P10253,P00403,P04062 12 +Aplasia hypoplasia of the clavicles 0.5559437328252291 1.3005027785050565 0.1934287045926681 1.0 0.4500098956121864 11 O75844,Q9Y619 2 +Long toe 0.566301092732332 1.297808082469986 0.1943532915708137 1.0 0.4519346309499502 10 P23786 1 +Tachycardia 0.4010125854791592 1.2923338912195477 0.1962415399397588 1.0 0.4554136835964632 30 P23786,P42892,Q9HD47,P36551,Q99959,Q14BN4,O43772,P21912 8 +Abnormal systemic blood pressure 0.3088041841981571 1.2900017534874295 0.1970500492814684 1.0 0.4569354590723283 93 O75844,Q10713,P07602,P42892,P16435,P03886,Q06787,Q9NZJ7,Q13423,P06280,Q9Y4P3,P21964,P35610,P00403,P04062 15 +Open mouth 0.3969688531375839 1.2888002551626827 0.1974675373114198 1.0 0.4574067887061414 31 P04350,P42345,P61978,Q10713,Q96PZ0,Q14738,P04062,Q86XL3 8 +Type ii lissencephaly 0.6723915918447496 1.288723606884983 0.1974941924546964 1.0 0.4574067887061414 5 O43505,Q8NAT1 2 +Lung adenocarcinoma 0.6234201546967604 1.2854957576847903 0.198619098254285 1.0 0.4590966818355265 3 P30154 1 +Congenital hepatic fibrosis 0.6715328467153265 1.2848370620367482 0.1988492281462885 1.0 0.4594000566721316 5 O15078,Q8NCM8,Q10713,Q9P2L0 4 +Absent epiphyses 0.6205538434229629 1.284199975448488 0.1990719937966227 1.0 0.4596302272889211 7 Q7LGA3,P36776,O60568 3 +Pharyngitis 0.6229474393586227 1.28323020566272 0.1994114364999539 1.0 0.4599390662452058 3 P01889 1 +Abnormal atrioventricular valve physiology 0.34347435343968 1.283038685480114 0.1994785231347589 1.0 0.4599390662452058 55 O75306,O75844,Q6NUK1,P53701,Q15904,P14854,Q8WVX9,Q9UL01,Q96L58,P01889,P06280,Q9Y4P3,P51812,Q9NZ08,P04062 15 +Restrictive ventilatory defect 0.5416743059126905 1.282505498755763 0.1996653772583672 1.0 0.4600847703878535 12 Q96L58,P16278 2 +Abnormality of adrenal morphology 0.4067063732829927 1.2822933146990694 0.1997397722497418 1.0 0.4600847703878535 29 O75844,O75874,P48735 3 +Multiple prenatal fractures 0.6552925537685734 1.2814871444631195 0.2000226125180866 1.0 0.4603932626519023 6 O75718,Q32P28 2 +Small cerebral cortex 0.5606767794632572 1.2808250188438184 0.2002551342058733 1.0 0.4605867646579367 2 Q14004 1 +Abnormal sella turcica morphology 0.5735672881715298 1.2805429450714705 0.2003542512642466 1.0 0.4605867646579367 9 P16278,P08236 2 +Abnormality of corneal size 0.3539794767174428 1.2771436064099475 0.2015515521873623 1.0 0.46240918452181 42 Q9H9S5,Q96L58,Q13045,O15078,Q9NWM8,O75845,O95202,O96028,Q9Y4P3,Q96EK5,P07437,Q9UIG0,Q8NAT1,O43505 14 +Abnormal ldl cholesterol concentration 0.5185451245468504 1.277106640722646 0.2015646007041203 1.0 0.46240918452181 14 Q15800,Q8N511,P37268 3 +Flat face 0.4361353643890743 1.2766667683349875 0.2017199185259697 1.0 0.46240918452181 24 Q9H9B1,O00754,Q03164,P36776,P40855,Q9Y487,Q96L58,O14974,Q9UM00,P07437,P08236,O60568,O60716 13 +Abnormal muscle fiber protein expression 0.618990697284584 1.2764142352528367 0.2018091267364614 1.0 0.46240918452181 7 P50402,Q9H9S5,Q8WXH0 3 +Cns demyelination 0.5183748935659003 1.276035491799573 0.20194297312277 1.0 0.46240918452181 14 Q9H9P8,P07602,P51648,Q9NZJ7,P49770,Q15067 6 +Abnormal upper motor neuron morphology 0.5517065690242332 1.2760347719040683 0.2019432275924995 1.0 0.46240918452181 11 P43243,Q04446,Q99720,P35637 4 +Skeletal muscle atrophy 0.2881862735803735 1.274050546418557 0.2026455031029237 1.0 0.4636294098700561 176 P51970,Q15120,Q8TB36,Q15165,Q13315,Q99720,Q9BQT8,O95831,O15269,Q99567,P16278,O15270,P50402,Q9NWM8,Q9NPL8,P31483,Q99519,Q6DKK2,P22626,P12235,Q92804,Q96RL7,Q6P4A7,P35637,P13473,O14979,Q13126,Q8NAT1,Q13510,Q9NR77,O60313,O60568 32 +Abnormal oral physiology 0.3423487404388305 1.2739653220785438 0.2026757062948954 1.0 0.4636294098700561 57 P55795,Q96RL7,Q15165,P35637,P15586,P01889,Q14738,Q9NR77,Q14739,Q92804 10 +Abnormal thyroid morphology 0.3629493327745148 1.2728577516756934 0.2030685234608598 1.0 0.4642993897633635 40 O75874,P48735,P42892 3 +Pectus carinatum 0.3628401638080685 1.271677215906935 0.2034878290835773 1.0 0.4643440343429765 40 P55795,Q96AY3,P16278,Q9Y619,Q99519,Q96L58,Q6DKJ4,P08236 8 +Proximal amyotrophy 0.5060787422321849 1.267842804881962 0.204854092560448 1.0 0.4670030000175867 15 P50402,P35637,O14979 3 +Basal ganglia calcification 0.5808301595122995 1.266277473642204 0.2054137588789353 1.0 0.4674824946045332 8 P03886,P00403 2 +Aplasia hypoplasia involving the vertebral column 0.4828126138649765 1.2661352029899635 0.2054646811639582 1.0 0.4674824946045332 17 Q6NUQ1,P16278,Q96HY6,P08236,Q14739,O95831 6 +Incomplete penetrance 0.3981611575941924 1.2660314949435354 0.2055018066923544 1.0 0.4674824946045332 30 P11166,P36551,P52701,P03886,Q06787,O14979,O43707,P49792,Q92733,P21912,O60313,Q6P2Q9 12 +Thoracic scoliosis 0.5273703723355682 1.2656804918947429 0.2056274953479713 1.0 0.4674824946045332 13 O75844 1 +Aplasia hypoplasia of the patella 0.6517143286009363 1.264766267980389 0.2059551267139168 1.0 0.4676337685320524 6 Q9Y619 1 +Hypertonia 0.2604193903049047 1.2643581309794905 0.2061015135643273 1.0 0.4676337685320524 393 P61916,O95630,Q9UBX3,Q7KZN9,P50897,Q15392,Q99720,P04062,Q15022,Q12768,P07602,P16278,Q9Y619,P49770,O43681,O75477,Q96D71,P17900,P55011,P03886,P43243,Q9NXE4,Q6DKK2,O60762,O14936,O75503,P51648,Q9UBM7,O15118,Q5XKP0,P51812,Q9H490,Q9Y320,Q9NZ01,Q7LGA3,Q8TD16,Q5JPH6,Q15165,Q8WVX9,Q8TAF3,P35658,Q9P0J0,Q86XL3,P49902,Q9H9P8,Q96KP1,Q9Y487,Q96N66,Q9Y287,Q15043,O43292,P55795,Q06787,P05067,P12235,Q14739,Q92804,Q6ZXV5,P35637,Q13510,P35610,Q9NP80,Q96CU9,P06865,Q15907,Q2TAA5,Q99797,Q10713,Q9Y4P3,Q15067,Q9NZJ7,Q99519,Q16625,Q96RL7,P11117,O60313,P51970,Q13315,O95831,O75306,P42695,Q9NVI7,P04350,P42858,O00584,Q9BW92,Q9Y2Z2 87 +Obsessive compulsive trait 0.6669861404124482 1.26425835058643 0.2061373133778827 1.0 0.4676337685320524 5 O75503 1 +Spastic paraparesis 0.4535183374301287 1.26086214941192 0.2073585173637604 1.0 0.4697160759005514 20 Q9Y619,P04062 2 +Upper motor neuron dysfunction 0.2604368178033128 1.258371116470154 0.2082575726297371 1.0 0.4712889833937476 396 P61916,O95630,Q9UBX3,Q7KZN9,P50897,Q15392,Q99720,P00403,P04062,Q15022,Q12768,P07602,P16278,Q9Y619,P49770,O43681,O75477,Q96D71,P17900,P55011,P03886,P43243,Q6DKK2,O60762,O14936,O75503,P51648,O15118,Q5XKP0,P51812,Q9H490,Q9NR77,Q9Y320,Q9NZ01,Q8TD16,Q5JPH6,Q15165,Q8WVX9,Q13423,Q8TAF3,P35658,Q9P0J0,Q86XL3,P49902,Q9H9P8,O14773,Q96KP1,Q9Y487,Q9NZ08,Q96N66,Q9Y287,Q15043,O43292,Q92804,Q6ZXV5,P35637,Q13510,P35610,Q9NP80,Q96CU9,Q15907,Q2TAA5,Q10713,Q9Y4P3,Q15067,Q9NZJ7,Q99519,Q96L58,O75569,P22626,Q16625,P42345,P01889,P11117,O60313,P51970,Q13315,O95831,O75306,Q9NVI7,P04350,P42858,O00584,Q9Y2Z2 84 +Abnormal spermatogenesis 0.4816043825611009 1.257815070321499 0.2084586441829856 1.0 0.4712889833937476 17 Q13315,Q13423,P04062,P16435 4 +Abnormal head movements 0.5369249120477457 1.2542841664983198 0.2097387368919814 1.0 0.4730828475884363 12 Q99720,Q06787,P35637 3 +Ankle clonus 0.5368587590949223 1.2538910371154346 0.2098816132419638 1.0 0.4730828475884363 12 Q9NZJ7,P07602,Q15043 3 +Coxa vara 0.5253162338420708 1.2531082528243038 0.2101663130015258 1.0 0.4730828475884363 13 Q96HY6,O75718,Q96AY3,Q9Y487 4 +Abnormal atrioventricular conduction 0.4686047850314092 1.2505419633000787 0.2111016361866837 1.0 0.4739217167983671 18 Q9HD47,Q99959,P50402,Q14BN4,P06280,O43772 6 +Macroglossia 0.3736391370252846 1.2504006146969886 0.2111532401576883 1.0 0.4739217167983671 37 Q7LGA3,P61978,Q10713,P16278,Q9Y4P3,P10253,Q96A33 7 +Limb pain 0.5577733714158828 1.2498865224467393 0.2113410034163918 1.0 0.4741141003730355 10 O15269,P36551,O15270,Q8WVX9,O75569,O75477 6 +Exercise induced muscle cramps 0.6480951487628487 1.247853506249553 0.2120847098422802 1.0 0.4749204370003907 6 P23786,P13473 2 +Hydrocele testis 0.6480787209473527 1.24777673812343 0.2121128297247541 1.0 0.4749204370003907 6 Q9UBX3 1 +Abnormal brainstem morphology 0.3061332098795408 1.2474210548705902 0.2122431503474648 1.0 0.4749204370003907 93 P11177,O00217,Q96CU9,Q92974,O43676,P30153,O95831,O75306,Q96RR1,Q96KP1,Q10713,Q9Y4A5,Q8TB37,Q86Y39,Q5T160,Q9UPT5,Q13813,Q96EK5,P07437,Q9Y6M9,Q9NPL8,P03886,Q9H9S5,Q06787,Q9NXE4,Q96C36,P49792,Q9BVA1,Q9P032,Q9Y5W7,O96000,O60762,O14936,Q6ZXV5,Q99496,Q9UNW1,O15078,Q13885,O43505,O60313,Q9Y320 41 +Aplasia hypoplasia of the lungs 0.3959046261920901 1.2452062994448976 0.2130559276314589 1.0 0.4758931921998838 30 O75844,Q6NUK1,Q8TAA9,O96000,Q99567,Q96L58,O96028,Q16134,O95202,P98175,Q14739 11 +Abnormality of skin pigmentation 0.2966038163461663 1.2441540078949318 0.2134428870492253 1.0 0.4762995452597026 141 Q7LGA3,Q06136,P51798,P16615,Q13315,Q13423,P21964,P00403,P04062,O75844,Q15022,P07602,P53701,P07437,P42858,O75648,P03886,O15360,Q9NZJ7,Q14739,Q8IZA0,P42345,Q96AY3,Q6PGP7,P51648,Q96PZ0 26 +Oligohydramnios 0.3855485564543747 1.2431811201225962 0.2138010982997633 1.0 0.4768098458790245 33 Q7LGA3,P23786,P16435,Q96L58,P51114,Q9UHX1 6 +Abnormal corneal epithelium morphology 0.4675412212391402 1.2429756058975203 0.2138768228178835 1.0 0.4768098458790245 18 O75844,Q9NZ08,P51648,Q14739 4 +Spastic paraplegia 0.3401623725844567 1.2418345169815883 0.2142976245524148 1.0 0.4772325280261222 55 O75306,P49902,Q5TBB1,Q12768,P11166,Q04446,Q96CU9,Q7KZN9,Q9Y619,Q15041,P04062,Q8TAF3,O60313,P54886,Q9P0J0,O95831 16 +Narrow mouth 0.309034994324312 1.241448573417146 0.2144400847919547 1.0 0.4772325280261222 79 O75844,Q6NUK1,Q7LGA3,P42858,O75648,P16435,Q6PGP7,Q9Y619,Q9Y487,Q9UL01,Q96PZ0,Q9NVI7,Q15392,P07437,P21964,P04062 16 +Increased circulating gonadotropin level 0.5561285575205482 1.2406420615967062 0.2147380064250905 1.0 0.4772325280261222 10 P16435,P82650,Q06787,Q96MF7,Q8IY37,P51659,P51809 7 +Entropion 0.5662524138105018 1.240504474555851 0.2147888602008323 1.0 0.4772325280261222 9 O75844 1 +Abnormal morphology of the radius 0.5127216660370111 1.2404572004111647 0.2148063352799467 1.0 0.4772325280261222 14 Q96L58,Q32P28,P98175,Q15427 4 +Aplasia of the phalanges of the hand 0.6139764517562839 1.2402358490873602 0.214888172326872 1.0 0.4772325280261222 3 Q9BXW9 1 +Progressive 0.3023724085038733 1.2388417878013398 0.2154040950557754 1.0 0.4781497494644685 116 Q9NP80,Q99720,P04062,O95831,Q12768,P28288,O75477,Q16637,Q96D71,Q15043,P04350,Q9Y6M9,P15586,O95470,P54802,P12235,O75569,Q8N1F7,Q12769,P52429,Q96RL7,O60762,Q13126,P27544,Q13510,O60313 26 +Hypopigmentation of the skin 0.3411986487479039 1.2380366650295422 0.2157024660264539 1.0 0.4785834083853414 49 P42345,P07602,P53701,Q6PGP7,O15360,Q9NZJ7,P21964,Q8IZA0 8 +Distal amyotrophy 0.3377937827047971 1.2366458683414865 0.21621858329477 1.0 0.4792707719406019 62 O15269,Q15120,Q8TB36,P31483,Q96RL7,Q13510,O15270,P35637,O60568,Q99720,Q9NR77,Q9BQT8 12 +Hypomimic face 0.5337739788554916 1.235558297684342 0.2166227939744933 1.0 0.4793916684101902 12 P04062,Q15043 2 +Abnormal metacarpal morphology 0.3873519140732671 1.234026475297346 0.2171930389145862 1.0 0.4800565455742947 32 Q32P28,P16435,P16278,P08236,Q14739 5 +Impaired distal proprioception 0.612008409287373 1.230805006707325 0.2183958025420822 1.0 0.4822561305183052 3 Q96RR1 1 +Microcytic anemia 0.5643370552756506 1.2300202107072886 0.2186895366249932 1.0 0.4824461477491541 9 Q9UBX3,Q9BQT8 2 +Axonal degeneration 0.6094755631153714 1.2290179137508326 0.2190650896631738 1.0 0.4830452807665428 7 Q6DKK2,Q9BQT8 2 +Deformed sella turcica 0.6582812346276168 1.2248604483816132 0.2206278047311216 1.0 0.4856368013817246 5 P08236 1 +Cholangitis 0.6107382550335498 1.224718903881579 0.2206811490736628 1.0 0.4856368013817246 3 Q96J02,Q9P2L0 2 +Bowing of the arm 0.6428956126910359 1.2235570206643775 0.2211193814156415 1.0 0.4856368013817246 6 Q32P28,P16435 2 +Psoriasiform dermatitis 0.6723886002289079 1.2229868491603353 0.2213346634035775 1.0 0.4856368013817246 4 Q15800,P01889 2 +Calvarial hyperostosis 0.6578556204467912 1.222934382830544 0.2213544808749232 1.0 0.4856368013817246 5 Q15043 1 +Bilateral cleft lip 0.6099629032975808 1.2210039195494613 0.2220845357596075 1.0 0.4867003552543096 3 Q9NXE4 1 +Abnormality of hair texture 0.3380825815404052 1.2202542831731944 0.2223684945759023 1.0 0.487092892880548 57 O75844,Q6NUK1,P42345,Q15022,P55795,Q6PGP7,P51798,Q9Y487,P15586,P54802,P51812,Q96A33,Q9NVI7,O60568 14 +Hypertriglyceridemia 0.439063223710061 1.2197698233292646 0.2225521439737621 1.0 0.4871355398816467 22 P28340,Q8WXH0,P50402,Q13045,Q9UJS0,P22830,O95470,Q96MF7,O75431 9 +Elevated circulating follicle stimulating hormone level 0.6713487178169395 1.218423502324741 0.2230630784303318 1.0 0.4871355398816467 4 P16435 1 +Respiratory insufficiency 0.28455943334889 1.2182040541507018 0.2231464394252122 1.0 0.4871355398816467 178 Q8TD16,P61916,P36551,Q15165,Q96CU9,Q70HW3,P06280,O43676,Q9UGP8,O95831,O75306,P23786,P07602,P53701,Q86Y39,Q99567,Q9Y619,P50402,Q15427,P10253,Q16637,Q15067,Q6NUK1,Q9Y6M9,Q9NPL8,O75648,P03886,P43243,Q9NXE4,Q9NZJ7,Q96L58,Q00325,P12235,O43772,Q14739,Q92804,Q96AY3,O76024,O96000,P35637,P13473,Q9BT22,Q5XKP0,Q13510,Q9NR77 45 +Elevated hepatic transaminase 0.3037200957613022 1.217985193251022 0.2232295995329813 1.0 0.4871355398816467 104 Q13315,Q8N511,Q2TAA5,P23786,Q10713,P08574,Q9Y619,P28288,Q9UJS0,P10253,Q15067,O75648,Q6NUQ1,O75845,P12235,O43772,Q16625,P09001,Q14739,Q96RL7,O60762,Q07021,Q15904,Q5HYI8,P01889,Q96MF7,Q5XKP0,Q16836,Q13510 29 +Glomerular sclerosis 0.3800370083089119 1.2177167790139405 0.2233316185854299 1.0 0.4871355398816467 34 P03886,Q14108,P00403 3 +Abnormal enzyme coenzyme activity 0.2772344657486708 1.2110606297817208 0.2258721688191438 1.0 0.4912133477380936 192 O14678,P61916,P05091,Q13315,Q99707,Q8N511,P04062,Q2TAA5,P23786,Q10713,P07602,P08574,P16278,Q9Y619,P10253,Q96EY8,Q15067,O75648,Q6NUQ1,P03886,Q9NZJ7,O75845,Q5JRX3,P22626,P12235,Q14566,Q16625,O43772,Q14739,P10619,Q96AY3,Q96RL7,Q15904,Q5HYI8,O15118,P01889,Q96MF7,Q8NAT1,Q96A33,Q13510 40 +Prominent nasolabial fold 0.6058339430565496 1.2108804574083238 0.2259412234430275 1.0 0.4912133477380936 7 Q9UL01 1 +Abnormality of the nasolabial region 0.6058339430565496 1.2108804574083238 0.2259412234430275 1.0 0.4912133477380936 7 Q9UL01 1 +Focal dystonia 0.4328048906684359 1.2087006254408403 0.226777881318297 1.0 0.492642794317763 23 Q96RL7,P35637,Q96L58,O75569,Q99720,Q15043 6 +Impaired tactile sensation 0.5602583700220034 1.2076958837548488 0.2271642619260399 1.0 0.492642794317763 9 O15269,Q9NR77 2 +Visual impairment 0.2635278322576719 1.2074444154114257 0.2272610392708833 1.0 0.492642794317763 303 Q7LGA3,Q5JPH6,P51798,Q9H061,Q92974,Q96CU9,O15460,P06865,O43676,P50897,Q15907,Q99707,P00403,O95831,O75306,O14773,Q10713,P07602,P37268,P53701,Q86Y39,P16278,Q13277,P49770,O43681,Q9Y4P3,Q9NZ08,Q96N66,Q9Y287,Q15043,P04350,P42858,P17900,O43292,P55011,Q9Y6M9,Q9NPL8,O75648,P03886,O15360,P61586,Q9NZJ7,Q99519,Q6P4Q7,P12235,O96000,O60762,O14936,Q6P4A7,O75503,P13473,P14854,P01889,Q96PZ0,Q5XKP0,P04439,Q9UHX1,Q96A33,Q96MF7,Q9H490,O60313,Q9NZ01 62 +Abnormality of metacarpal epiphyses 0.6390309971899096 1.205501353061187 0.2280098160001871 1.0 0.4936104444108173 6 O96028,O95202,P16435 3 +Abnormal clavicle morphology 0.4460925511240766 1.2052514466427906 0.2281062471265658 1.0 0.4936104444108173 20 O75844,Q96AY3,Q9Y619,Q14739 4 +Fever 0.3030469347318191 1.2018221248950076 0.2294324514503511 1.0 0.4955460755920122 89 P23786,P61978,P07602,P03886,Q9NZJ7,O15460,P01889,P06280,P10253,Q9NZ08,Q13510,Q9NR77,P35610,P00403,Q14739 15 +Neonatal death 0.5169236035119902 1.2017359916151953 0.2294658318221629 1.0 0.4955460755920122 13 Q6NUK1,Q16134,P04062,Q9NVI7,Q14739 5 +Lower limb pain 0.6530709625503021 1.201284910141417 0.2296407018402071 1.0 0.4955460755920122 5 O75477,O75569,Q8WVX9 3 +Abnormality of hindbrain morphology 0.2653445940017166 1.200412334718181 0.2299792407555037 1.0 0.4960462175255664 297 Q8TD16,P51970,P11177,P51798,Q96CU9,Q92974,Q8WVX9,Q9UM00,Q9UBN7,O95202,Q15907,Q99720,P98175,P35658,P23786,Q9H9P8,Q96KP1,O43683,Q12768,O14773,Q10713,Q99567,Q9UPT5,Q9Y487,P78527,P46977,Q9Y4P3,P07437,O75477,Q14108,P21912,Q96D71,Q15043,Q6NUK1,Q9NVI7,O43292,Q8N201,P55795,P04350,P42858,O75648,Q06787,P00374,Q9NXE4,Q13535,Q6DKK2,P13073,O96028,Q5JRX3,O75845,P12235,Q16625,Q8TAA9,P16435,O60762,O14936,Q8NFH4,O75503,P51812,Q9UBM7,P35637,Q9BT22,Q8TCJ2,Q8NAT1,Q5XKP0,Q03154,Q8IV08,Q9H490,O60313,Q9Y320 70 +Glucose intolerance 0.3015828416703375 1.1993509982306396 0.2303914927879029 1.0 0.4965728507936105 110 Q06136,Q96CU9,Q13315,O43676,P00403,O75844,O75306,Q86Y39,P43304,Q9Y4P3,Q9Y6M9,Q9NPL8,P03886,Q06787,Q9NXE4,P12235,Q8TAA9,O76024,Q5HYI8,Q96MF7,O60313 21 +Hand polydactyly 0.3719783658643438 1.1992229059314123 0.2304412828367996 1.0 0.4965728507936105 36 Q10713,Q12768,Q9UBM7,Q13045,O75845,O96028,O95202,Q9UHX1,P98175,P21964,Q14739,Q15067 12 +Capillary hemangioma 0.5682133005755126 1.1989585938194718 0.2305440463111963 1.0 0.4965728507936105 8 Q7LGA3,Q9UHX1 2 +Abnormality of circulating enzyme level 0.3029908035978297 1.1971948197745563 0.2312306285017049 1.0 0.4978208989893054 97 Q15120,P53985,O95831,P23786,P50402,Q9NWM8,Q9Y4P3,P10253,O75648,P31483,Q5JRX3,P22626,P12235,Q96RL7,Q6ZXV5,P13473,O14979,Q8NAT1,Q9Y584 19 +Aplasia hypoplasia of the capital femoral epiphysis 0.6364143658457044 1.1932786424119142 0.2327602640678741 1.0 0.5004184113185298 6 Q7LGA3 1 +Abnormality of the adrenal glands 0.3349409736394606 1.192061938541639 0.2332369596994434 1.0 0.5008054934724445 60 O75844,O75874,P48735,Q13423,O95470 5 +Hypoglycemic seizures 0.6361392733920267 1.19199377385976 0.233263686585099 1.0 0.5008054934724445 6 P53985,Q13423,Q16836 3 +Distal sensory impairment of all modalities 0.66490077877115 1.1901344672641598 0.2339935451270003 1.0 0.5013179156050402 4 O15269 1 +Distal sensory loss of all modalities 0.66490077877115 1.1901344672641598 0.2339935451270003 1.0 0.5013179156050402 4 O15269 1 +Ectrodactyly 0.4716632773085655 1.1893397939807986 0.2343059820193045 1.0 0.5013179156050402 17 Q8TB36,O96028,O95202,Q99720,Q9NR77 5 +Polymicrogyria 0.3012469662097629 1.185740323766448 0.2357248648812695 1.0 0.5032336256302914 83 P23786,Q10713,P37268,Q6ZXV5,Q9Y487,Q8NAT1,Q15427,Q15392,P07437,Q16625,Q96N66 11 +Breech presentation 0.5657310264021295 1.185718170575309 0.2357336162776953 1.0 0.5032336256302914 8 O75718,O60313,Q9Y619 3 +Recurrent paroxysmal headache 0.5359924408060749 1.1852690886508843 0.2359110711628873 1.0 0.5032336256302914 11 P00403 1 +Anteriorly placed anus 0.5358741323654801 1.18458587643078 0.2361812239331189 1.0 0.5035786904053559 11 P48651,P53701,Q15022,P16435 4 +Dyschromatopsia 0.6342802950040487 1.1833118335448083 0.2366855846534115 1.0 0.5044225808714449 6 Q9H061 1 +Chorea 0.3017180415733222 1.1823485871113886 0.2370674141978974 1.0 0.5050046796714496 88 O75306,P04350,P17900,P42858,P55011,P07602,Q96RL7,P03886,O14936,P35637,Q9NZJ7,Q9BWD1,Q13315,Q5XKP0,O43681,Q99720,Q96N66,Q9P0J0 18 +Abnormality of the gastric mucosa 0.4818010112039293 1.1814489088354845 0.2374244383968662 1.0 0.5054461645705319 16 P04062,O76024,Q14739,Q9Y4P3 4 +Peripheral demyelination 0.4338724555056483 1.1794358473529427 0.2382246679098119 1.0 0.5065408728187579 22 P03886,Q9NR77,P07602,Q9NZJ7 4 +Atrophy degeneration affecting the cerebrum 0.2744704850323135 1.177383598796314 0.2390424331522729 1.0 0.5080471840921592 256 Q7LGA3,Q8TD16,P51970,O14678,O95630,Q8WVX9,Q9UM00,P50897,Q99707,P00403,P04062,P35658,Q2TAA5,Q9H9P8,O14773,O95831,Q10713,P07602,P16278,Q9Y619,Q9UPT5,Q9NWS8,Q9Y4P3,Q96N66,Q96D71,Q15043,P42858,P17900,O75648,P55011,P03886,Q06787,P00374,P05067,Q9NZJ7,Q9UL01,Q6DKK2,P13073,O75845,Q5JRX3,Q16625,O76024,Q96RL7,O60762,O14936,O75503,Q9BT22,Q96PZ0,Q9UHX1,Q03154,P51812,Q96A33,Q9H490,O60313,Q9Y320,Q9NZ01 56 +Babinski sign 0.3013789685628625 1.177008301878353 0.2391921926997064 1.0 0.5081330257351789 88 Q8WVX9,Q99720,O95831,P49902,O14773,Q12768,P07602,P11166,O43681,O75477,Q15067,Q15043,P42858,Q9NZJ7,Q6DKK2,P35637,P51812,Q9NR77,O60313 19 +Polycystic liver disease 0.6610821161473057 1.1733879827625964 0.2406402540963956 1.0 0.5097097834920256 4 Q9UGP8 1 +Abnormal large intestine physiology 0.4375552609681539 1.1731124876287382 0.2407506994163943 1.0 0.5097097834920256 21 Q8TAA9,P07602,Q06787,Q9NZJ7,P06280,P21964 6 +Neoplasm of the breast 0.3809186609427189 1.1725706935982456 0.2409680074518674 1.0 0.5097097834920256 32 O75874,P48735,P52701,Q99496,Q07864,Q5HYI8,Q13315,Q13535,P49327,P21912 10 +Paraplegia 0.3337579501333233 1.1724124341449482 0.2410315097572062 1.0 0.5097097834920256 59 O75306,P49902,Q96CU9,Q7KZN9,Q9Y619,Q96L58,P04062,Q8TAF3,O60313,Q9P0J0,O95831 11 +Lower extremity joint dislocation 0.302145969219168 1.1705567512407835 0.2417769900321498 1.0 0.5110536377112684 80 O75844,Q6ZXV5,Q9Y487,Q96L58,Q13535,Q96PU5,O96028,O95202,Q9UHX1,Q15427,Q96A33,P21964,Q9Y4P3,Q14738 14 +Abnormal circulating dicarboxylic acid concentration 0.3350042057943649 1.168955708104255 0.2424214769502288 1.0 0.5119500826867106 45 Q9H9P8,P23786,O75648,O14678,P37268,P11166,P36551,P48735,O14936,P28288,O75845,Q16134,Q96EY8,Q9UGP8,Q14739 15 +Horizontal pendular nystagmus 0.5393815635939474 1.168563220656208 0.2425796538244706 1.0 0.5120513728616496 2 P55265 1 +Absent septum pellucidum 0.3688380161461229 1.1674430838381495 0.2430314807057179 1.0 0.5123306712310028 36 P53701,P48651,P51571,Q8NAT1,O96028,Q15392,Q96N66 7 +Abnormal visual fixation 0.6302368772405285 1.1644331783959287 0.2442485084170589 1.0 0.5139725796586945 6 Q13510,P04062 2 +Abnormal pleura morphology 0.4170055220009666 1.164331792621981 0.2442895771939386 1.0 0.5139725796586945 25 Q9UL01,Q96L58,P01889,Q9NZ08,P08236,Q14739 6 +Slowly progressive 0.3338021070095919 1.1641213855511678 0.2443748231739251 1.0 0.5139725796586945 56 O14773,Q15120,P31483,O14979,P50402,P12235,Q99720,Q9NR77,Q8IV08,Q9P0J0,O95831 11 +Echolalia 0.5521968157337047 1.1635872383186985 0.2445913255969234 1.0 0.5141951577933512 9 Q9UHX1 1 +Low frustration tolerance 0.5519631374639882 1.162309152216466 0.245109910324953 1.0 0.5148194590279076 9 Q9UHX1,P04062 2 +Abnormality of cardiovascular system electrophysiology 0.2953436954314841 1.1583984188548015 0.2467014841141797 1.0 0.5173292127323909 123 P51970,Q8TB36,O15460,P06280,P00403,P04062,O75306,P23786,O43572,P07602,P53701,P50402,Q9Y4P3,P10253,P42892,P03886,Q9NZJ7,Q99519,P12235,O43772,Q9HD47,P13473,P01889 23 +Mandibular prognathia 0.3385825243675571 1.1570423422754736 0.247255061400812 1.0 0.5176868027346428 43 Q6NUK1,Q15022,P55011,P48651,P16278,Q06787,Q9NXE4,Q13045,Q9UHX1,Q9NVI7 10 +Abnormal forearm bone morphology 0.4212400709940196 1.156337912974106 0.2475429664115922 1.0 0.5177418642600545 24 Q32P28,P16435,Q96L58,Q13535,Q15427,P98175 6 +Hepatic cysts 0.6571702879393784 1.1562401616016236 0.2475829365932722 1.0 0.5177418642600545 4 Q9UBS4,Q9UGP8 2 +Pulmonary hypoplasia 0.4158076281653516 1.154451792287763 0.2483149918617777 1.0 0.5187749120093336 25 O75844,Q6NUK1,Q8TAA9,O96000,Q99567,Q96L58,Q16134,P98175,Q14739 9 +Ovarian neoplasm 0.4306197881018364 1.1541616417688918 0.248433905377345 1.0 0.5187749120093336 22 O75874,P48735 2 +Brain imaging abnormality 0.3562278715764232 1.1541352534656948 0.2484447221740782 1.0 0.5187749120093336 39 O75306,P07602,P03886,Q9NZJ7,P35610,P00403 6 +Abnormality of the tarsal bones 0.4098692502659557 1.150321474312277 0.2500114893078753 1.0 0.521275173453889 26 O75844,P16435,Q99567,Q9UPT5,Q9NXE4,Q9UBN7,Q9UHX1,P98175,Q14739 9 +Retinal telangiectasia 0.6555644047931357 1.149203107642725 0.2504722397565722 1.0 0.5218358860578629 4 P03886 1 +Hypoketotic hypoglycemia 0.5928888246216146 1.146444600124996 0.25161123752733 1.0 0.5237391619856521 7 O43772,P23786 2 +Dysarthria 0.2859814283099685 1.146047163109036 0.2517756379921489 1.0 0.5238077437071015 166 P61916,Q9NP80,Q96CU9,Q7KZN9,Q13315,Q9P0J0,P04062,O75306,O14773,Q10713,P07602,P49770,O43681,Q9Y4P3,O75477,Q14108,Q96D71,P04350,O43292,Q06787,P15586,Q9NZJ7,Q6DKK2,O75569,P12235,O76024,Q96RL7,O75503,P51648,P35637,O15118,Q8IV08 32 +Abnormality of female external genitalia 0.3553963154730209 1.145290839526384 0.2520886993580455 1.0 0.5238077437071015 39 Q6NUK1,P53701,P16435,P40855,Q9Y619,Q9UBM7,Q13535,Q6DKJ4,Q15392 9 +Ventricular escape rhythm 0.6406834898850535 1.145275237373167 0.2520951603377268 1.0 0.5238077437071015 5 P50402,Q8WXH0 2 +Eeg with focal spikes 0.6403068706720227 1.1435736574604132 0.2528004915419339 1.0 0.5245694880320791 5 O75503,Q86YH6 2 +Angiofibromas 0.5936550924327295 1.1429306120259333 0.2530674014858347 1.0 0.5246546842049032 3 P21912 1 +Adenoma sebaceum 0.5936550924327295 1.1429306120259333 0.2530674014858347 1.0 0.5246546842049032 3 P21912 1 +Abnormal morphology of the conjunctival vasculature 0.5919298719883638 1.1416750258928023 0.2535891254184006 1.0 0.5253681146909022 7 P10619,P06280 2 +Middle age onset 0.538440552112386 1.141266563574507 0.2537590119117412 1.0 0.5253681146909022 10 P31483,P07602 2 +Synostosis of joints 0.3590694515088292 1.1410146090525328 0.2538638436248548 1.0 0.5253681146909022 38 P16435,P48651,Q96L58,O96028,O95202,Q15427,Q6DKJ4,Q9UHX1,Q9Y4P3 9 +Abnormality of the calf musculature 0.4529756994997544 1.1393404809740235 0.2545611703247519 1.0 0.5265766684455909 18 Q9NR77,Q8NAT1,Q12768,Q96RL7 4 +Cerebral calcification 0.3747855916715338 1.1389340227742226 0.2547306737109656 1.0 0.5266927948647735 33 P23786,P03886,P05067,O75845,Q16625,O60313,P00403 7 +Fulminant hepatic failure 0.5920066243322921 1.1350483102054272 0.2563550773508474 1.0 0.5290679238134735 3 Q16836 1 +Abnormal renal cortex morphology 0.3310946845246149 1.1322118673464032 0.2575453720306302 1.0 0.5305367507672236 57 Q02978,Q92621,Q12769,P52429,Q6PGP7,P03886,Q8NFH4,Q14108,P01889,P06280,Q16134,O95470,O43707,Q9NZ08,P21912,P00403,Q8N1F7 17 +Impaired visuospatial constructive cognition 0.5463219610184441 1.131466849851012 0.257858648531164 1.0 0.5307980864314524 9 P03886,Q10713,P00403 3 +Head tremor 0.4949422813847702 1.1285747394497183 0.2590772717641898 1.0 0.5323845970389446 14 Q99720,P35637 2 +Thoracolumbar kyphosis 0.5891896836336648 1.128049903270725 0.2592988444032063 1.0 0.5323845970389446 7 P04062 1 +Decreased adenosylcobalamin 0.590003686269319 1.1254743053323502 0.2603880994488945 1.0 0.5326357945393377 3 O14678 1 +Diffuse white matter abnormalities 0.5355896855206914 1.125266114708054 0.2604762841698318 1.0 0.5326357945393377 10 O75306,O14936,Q9H9S5,P16278 4 +Microglossia 0.6496512855040677 1.1233061346788986 0.2613074992709672 1.0 0.5338762715975873 4 P48651 1 +Abnormal lung lobation 0.4937165580684315 1.1208679097704135 0.2623440922429085 1.0 0.5350529642495844 14 P21964,O43683,Q14739,Q9UHX1 4 +Abnormality of the wrist 0.3787411456191754 1.1176720549455053 0.2637070821000189 1.0 0.5368900540914495 31 O75844,P16435,P16278,Q96L58,Q6DKJ4,Q13510 6 +Abnormal palmar dermatoglyphics 0.3263950967516848 1.117230254560094 0.2638958877673869 1.0 0.5368993318419341 65 P61978,O95202,Q6DKJ4,Q15907,Q5SRE5,P98175,Q96J02,Q99567,P36776,Q9Y487,Q6NUK1,Q9H2P0,Q9NXE4,Q9UL01,Q13535,P62266,O96028,P42345,P40855,P27635,Q9UHX1,P51812,O60568 23 +Non midline cleft lip 0.6200603522160679 1.1169622756652295 0.2640104553445241 1.0 0.5368993318419341 6 Q96L58,Q15427 2 +Neck flexor weakness 0.6481651386147458 1.116801488395246 0.2640792123249775 1.0 0.5368993318419341 4 Q99720 1 +Ureteral duplication 0.586776576478364 1.1160563280740738 0.2643980242304675 1.0 0.5369832454703698 7 O75844 1 +Impaired mastication 0.5864064237466393 1.1142170691050448 0.2651860744267313 1.0 0.5380567542133703 7 P01889,Q14738 2 +Abnormal endocardium morphology 0.4607329744505327 1.1140738893643638 0.2652474891342091 1.0 0.5380567542133703 17 Q9NZ08,P06280,P04062,Q9Y4P3 4 +Decreased number of large peripheral myelinated nerve fibers 0.6191148298767323 1.1125556104394676 0.2658993339299509 1.0 0.5385214932164568 6 O15269 1 +Thoracic hypoplasia 0.3781078360130184 1.1117246554940383 0.2662565555567731 1.0 0.5390100031009881 31 P42345,P16435,Q9UHX1,P04062,Q96HY6,O75718,Q14739 7 +Joint contractures involving the joints of the feet 0.5425178250252282 1.110683739237284 0.2667045038882376 1.0 0.5393555026864401 9 P49902 1 +Glossitis 0.5863694126548704 1.1081124892536625 0.2678132378380355 1.0 0.5407476327664117 3 P01889 1 +Orthostatic hypotension due to autonomic dysfunction 0.5324328765112802 1.1075575990761857 0.2680529238116902 1.0 0.5409964743827597 10 Q9NZJ7,P07602,P04062 3 +Abnormal nasal mucosa morphology 0.5848108100393673 1.10629010332067 0.268600973986711 1.0 0.5418671841694569 7 Q03519 1 +Paresthesia 0.4097089369537388 1.1041623192442322 0.2695227318589057 1.0 0.5423138207953556 25 P05067,P01889,P06280,P54802,Q9NZ08,Q9NR77 6 +Elevated gamma glutamyltransferase level 0.6449973545550156 1.1029427121884623 0.2700520441414187 1.0 0.5429086097278369 4 Q5XKP0,Q9UJS0 2 +Atrophy degeneration affecting the brainstem 0.5006320432275779 1.1020859844799895 0.2704242919749116 1.0 0.5431007144255517 13 Q5T160,O60313,Q9Y4A5,Q96RR1 4 +Ankyloblepharon 0.6447625410873391 1.1019157755901816 0.2704982895352403 1.0 0.5431007144255517 4 O75569 1 +Neuropathic arthropathy 0.6443633120704838 1.1001698976595913 0.271258103659846 1.0 0.5442339356165192 4 O15269 1 +Craniofacial osteosclerosis 0.584687148962244 1.1000806461907706 0.2712969855548555 1.0 0.5442339356165192 3 Q15043 1 +Extramedullary hematopoiesis 0.6442199643989149 1.0995430564723756 0.2715312642144285 1.0 0.5444688189642792 4 Q14739 1 +Coarse hair 0.4277749892670822 1.098545178349851 0.2719665012609109 1.0 0.5447122309569226 21 Q6NUK1,P15586,Q9Y487,P54802,P51812,Q96A33,O60568 7 +Female hypogonadism 0.5831797658337158 1.0981897778159235 0.2721216289390911 1.0 0.5447122309569226 7 O75844 1 +Abnormal patella morphology 0.3861257153828596 1.0967904841173095 0.2727329909406042 1.0 0.5457008940181082 29 Q6ZXV5,Q9Y619,Q96PU5,Q9Y4P3,P21964 5 +Recurrent respiratory infections 0.2886019396662294 1.0903977256142348 0.275537983296432 1.0 0.5489491725536977 136 P51798,O15460,Q13315,O95202,Q6DKJ4,Q9H0U3,P08236,P04062,Q12768,P07602,P16278,Q13277,Q9Y487,Q9UJW0,Q9Y4P3,P10253,P09601,Q9NPL8,P15586,Q9NZJ7,O96028,Q03519,P54802,Q03518,P01889,Q13510,Q8N5M9 27 +Tremor 0.2784100383197155 1.089279621873365 0.276030596323382 1.0 0.5495765904620593 178 Q15120,Q13315,Q99720,P04062,O95831,O75306,O14773,Q10713,P07602,Q9Y4P3,Q9Y287,Q14108,Q15043,P04350,O43292,P03886,Q06787,Q9NZJ7,Q99519,Q6DKK2,Q5JRX3,O75569,P12235,Q96RL7,Q6P4A7,O75503,P35637,Q13510,Q9NR77,O60313 30 +Photophobia 0.3541064694349517 1.0891460437271638 0.2760894881916587 1.0 0.5495765904620593 38 P07602,P51648,Q9NZJ7,P04439,Q9NZ08,Q9Y287 6 +Abnormal macular morphology 0.3754622739627135 1.0868844394635515 0.277087883995923 1.0 0.551091741885727 31 P51648,P04439,P50897,Q13510,P04062 5 +Myopia 0.2953696077713439 1.0841677565721624 0.2782904250443536 1.0 0.5527735420077242 106 P49902,O43292,P61978,P51648,P61586,Q9Y487,Q9UL01,Q96L58,O15460,Q9NWM8,Q9UHX1,Q9Y4P3,P12235,P98175,Q9NVI7,O60568,Q14738,Q15067 18 +Paraplegia paraparesis 0.2948588694944682 1.0835502524906797 0.278564258243136 1.0 0.5530810016229103 84 Q96CU9,Q7KZN9,Q8WVX9,Q8TAF3,Q9P0J0,P04062,P49902,O95831,O75306,Q12768,P11166,Q9Y619,P21912,Q15041,Q96L58,Q6DKK2,P35637,Q5XKP0,Q13510,O60313 20 +Metaphyseal striations 0.6266721763126732 1.0820471094559692 0.2792315956151769 1.0 0.5541691555865493 5 Q13126 1 +Headache 0.3121598799278036 1.0808388687542465 0.2797687952599343 1.0 0.5549487681311059 72 O15460,O43707,P49327,P00403,P04062,P23786,P11166,P52701,Q9NZ08,P21912,Q5TBB1,Q02978,P03886,P05067,P12235,Q8N1F7,Q8TAA9,Q92621,Q12769,Q9BW27,Q8NFH4,P01889,O60313 23 +Occipital meningocele 0.626278153330009 1.080271670243095 0.2800212212645363 1.0 0.5549487681311059 5 P21964 1 +Skin tags 0.4253652201036846 1.0801869486021551 0.2800589390609702 1.0 0.5549487681311059 21 Q12768,O96028,O95202,Q15427,Q9UHX1,Q96MF7 6 +Hypoplastic female external genitalia 0.4665833661682722 1.0799285813737172 0.280173984618103 1.0 0.5549487681311059 16 Q9Y619,Q6DKJ4,P16435 3 +Mitral valve prolapse 0.401460834824524 1.0795118146364784 0.2803596298464224 1.0 0.5549487681311059 26 P55795,P53701,Q06787,Q9UL01,Q9Y4P3 5 +Leukodystrophy 0.3249951628078475 1.0793353194167463 0.2804382733338328 1.0 0.5549487681311059 64 O75306,Q9Y6M9,Q9NPL8,P07602,Q86Y39,P03886,Q96CU9,Q9NZJ7,P14854,O43676,Q9P0J0,Q15067 12 +Undetectable visual evoked potentials 0.6395235576140061 1.079017346403784 0.2805799949074403 1.0 0.5549487681311059 4 P14854 1 +Decreased ldl cholesterol concentration 0.6391227479902062 1.0772666513189495 0.2813611562887015 1.0 0.5555667176213855 4 Q15800 1 +Abnormal lactate dehydrogenase level 0.4289792688306164 1.0771233806496456 0.2814251490344837 1.0 0.5555667176213855 20 P10253,P23786,Q8NAT1,Q5JRX3 4 +Prominent forehead 0.2946059719659222 1.0769774820377025 0.2814903257169052 1.0 0.5555667176213855 85 Q7LGA3,Q15392,P23786,Q15022,Q10713,P11166,P42858,O43292,O75648,P55011,Q06787,P15586,Q96L58,Q14739,P42345,P48651,O14936,Q6PGP7,Q96PZ0,Q9UHX1,P51812,Q14738 22 +Vegetative state 0.6253798734602674 1.0762247206259 0.2818267664522693 1.0 0.5555698889289572 5 Q9NZJ7,P07602 2 +Tetraplegia 0.4866024667357204 1.0761712539903736 0.2818506733115695 1.0 0.5555698889289572 14 P51572,P51970,Q13423,O43681,P54886,O95831 6 +Spastic paraparetic gait 0.6251743692753076 1.0752990046912574 0.2822408816878612 1.0 0.556103111247584 5 Q15043 1 +Abnormal gallbladder morphology 0.3680515440755856 1.0737150451944355 0.2829504160962148 1.0 0.557221605618792 33 P07602,Q9NZJ7,O75845,P22830,Q9Y4P3,Q96A33,P21964,P04062 8 +Abnormality of the 3rd toe 0.5212952158693281 1.0734964592940497 0.2830484264443282 1.0 0.557221605618792 2 P02545 1 +Increased ldl cholesterol concentration 0.526150337386801 1.0723497180076864 0.2835629833811133 1.0 0.5577619054990061 10 Q8WXH0,P34913,P50402,Q9UJS0,Q8N511 5 +Saccadic smooth pursuit 0.6243793697204164 1.0717182925359583 0.2838465820532796 1.0 0.5579263932728729 5 O14773,Q06787 2 +Ophthalmoparesis 0.3115073792452519 1.0716288207480449 0.2838867829739715 1.0 0.5579263932728729 72 O75306,Q10713,O76024,P03886,Q96CU9,O15460,P01889,P04062,P12235,O60313,P00403,Q9P0J0 12 +Increased circulating lactate dehydrogenase concentration 0.4756765080550159 1.070982131089549 0.2841774642674846 1.0 0.558261521770289 15 P10253,P23786,Q5JRX3 3 +Recurrent aspiration pneumonia 0.5771518136524427 1.0682791098303606 0.2853946287895077 1.0 0.5601788953764482 7 Q6NUK1,P78318,Q13510,P04062 4 +Abnormality of the upper arm 0.4234482368681826 1.065589246615231 0.2866093623508401 1.0 0.5618510959839677 21 P48651,O15228,O14979,P16435 4 +Dermal translucency 0.5339612925265875 1.0639982724954695 0.2873294821225896 1.0 0.5627878473615309 9 O75844,Q96L58 2 +Dyscalculia 0.5335044513162785 1.0615085464922187 0.2884588509780106 1.0 0.5642658819194476 9 Q06787,P35637 2 +Inappropriate antidiuretic hormone secretion 0.5189614935822806 1.0612641003829153 0.2885698957039619 1.0 0.5642658819194476 2 P50336 1 +Abnormal tricuspid valve morphology 0.5143484801099499 1.060461344891948 0.2889347667401822 1.0 0.5647416601913701 11 P21964,Q12768,Q6DKJ4,P53701 4 +Intrauterine growth retardation 0.2719949522829396 1.0597472649854545 0.2892595938111031 1.0 0.5651388027108432 211 P11177,P51798,Q96CU9,Q9UBN7,O43676,O95202,Q15392,Q5SRE5,P98175,P21964,P04062,O75844,O75306,O43683,Q12768,P37268,Q86Y39,Q99567,P16278,Q9Y619,Q9Y487,P78527,Q9UJS0,Q15427,P21912,Q6NUK1,P51572,P82663,Q9Y6M9,Q9NPL8,P03886,Q06787,O15360,Q9NXE4,Q96L58,Q13535,O75845,O96028,Q9P032,Q86YH6,O96000,Q6P4A7,P48651,Q6PGP7,Q9UBM7,P14854,Q9BT22,Q8TCJ2,Q9UHX1,Q9Y584,Q16836,O60568 52 +Hyperkinetic movements 0.5040580841044588 1.0591619747176313 0.2895260192730098 1.0 0.5654215576050456 12 Q9NZJ7,P07602 2 +Abnormal thrombosis 0.3989948381894525 1.0587615141655642 0.2897084050185283 1.0 0.5655400208891104 26 Q9NZ08,O75874,P48735,P01889 4 +Periventricular heterotopia 0.5036498048715139 1.0567448681366385 0.2906280418001583 1.0 0.5669495657534823 12 Q6NUK1,P11177,Q6ZXV5,Q06787,Q96PU5 5 +Abnormality of the abdominal wall 0.2869930589723641 1.0537404312221847 0.2920017727134389 1.0 0.568944047202086 129 P51970,O14678,Q6DKJ4,P21964,P08236,O75844,Q32P28,Q15022,Q10713,Q12768,P16278,Q9Y487,Q9NWM8,Q15427,Q9Y4P3,P07437,Q6NUK1,O15360,Q9UL01,Q99519,Q14739,P42345,P48651,O14936,Q6PGP7,Q9UBM7,Q9UHX1,Q96HY6 28 +Accessory spleen 0.540913445521221 1.0536035234485603 0.2920644753717123 1.0 0.568944047202086 8 Q15904,Q96KP1,O96028,O95202 4 +Hyperintensity of cerebral white matter on mri 0.4175018451407564 1.052317250786411 0.2926540196166574 1.0 0.5692049893190549 22 P17900,P07602,O75503,P10253,Q15043 5 +Developmental regression 0.286523641291628 1.0522420992518855 0.2926884889115846 1.0 0.5692049893190549 132 P06280,O95831,O75306,O14773,P07602,P16278,Q9Y4P3,Q9NZ08,Q15067,Q15043,P17900,P55795,Q9NVH6,P03886,Q9NZJ7,Q99519,P13073,O95470,O75503,P01889,Q13510 21 +Noncompaction cardiomyopathy 0.5744813270697434 1.0514301622664326 0.2930610689043038 1.0 0.569334565207152 3 P21912 1 +Abnormality of the alveolar ridges 0.6331812481495726 1.051336243498692 0.2931041866895807 1.0 0.569334565207152 4 P98175,Q15392 2 +Neoplasm of the endocrine system 0.3380355526117367 1.0489028569092087 0.2942228305169372 1.0 0.5709938473607729 41 O75874,P48735 2 +Gingival overgrowth 0.3742846541037116 1.0455561393922894 0.2957660084782691 1.0 0.5730312240992654 30 P16278,Q9UBM7,Q99519,O75845,Q6DKJ4,Q9Y4P3,P08236,Q14739 8 +Abnormal testis morphology 0.2712691607343458 1.045102933480884 0.2959753984278568 1.0 0.5731978745709974 234 Q7LGA3,Q06136,P61978,O14678,Q9UBX3,Q13315,Q13423,O95202,Q6DKJ4,Q01844,P98175,P21964,Q86XL3,P37268,P53701,Q99567,Q9Y619,Q9Y487,P46977,Q9Y4P3,Q9NZ08,P07437,Q9NVI7,P42858,O75648,Q06787,O15360,Q9UL01,Q13535,Q96PU5,P51114,O96028,O95470,P38159,P42345,Q8TAA9,O76024,P16435,P48651,P01889,Q8NAT1 41 +Increased blood pressure 0.3019212848986961 1.041693614625556 0.2975537503783056 1.0 0.5752991967902991 76 O75844,Q10713,P42892,P16435,P03886,Q06787,P06280,Q9Y4P3,P21964,P35610,P00403,P04062 12 +Cranial hyperostosis 0.4907160804150093 1.0415728884623177 0.29760974376557 1.0 0.5752991967902991 13 P09651,O00754,P18074,P48651,Q96L58,P22626,P51812,Q15043 8 +Abnormality of the abdominal organs 0.2510385411832925 1.0408797910142884 0.2979313420203813 1.0 0.5752991967902991 368 P61916,Q96CU9,P51798,Q7KZN9,P53985,Q13315,O43676,O95202,Q15392,Q01844,Q8N511,Q16134,P21964,P08236,P00403,P04062,Q9H0U3,O75306,P23786,Q10713,P07602,Q86Y39,P16278,Q9Y619,Q9UJW0,Q9NWS8,Q9Y4P3,P10253,Q9NZ08,P22830,P09601,Q14108,Q96EY8,Q9NVI7,Q15067,Q9Y6M9,Q9NPL8,O75648,Q6NUQ1,P03886,O15360,P00374,P15586,Q9UL01,Q9NZJ7,Q99519,O75845,O96028,P54802,P12235,P22626,Q16625,O43772,Q14739,Q9BW92,P10619,Q12769,O76024,Q96RL7,Q6PGP7,Q14376,Q15904,Q5HYI8,Q9BT22,O15118,P01889,Q96MF7,Q9UHX1,Q96HY6,Q96A33,Q13510,P35610 72 +Genu valgum 0.3532007030169292 1.040414372346898 0.2981474272333311 1.0 0.5752991967902991 37 Q7LGA3,P16278,Q9Y619,Q9Y4P3,Q9NR77,P08236 6 +Proximal muscle weakness 0.3219753291463302 1.039640952584333 0.2985067430851376 1.0 0.5755020672860721 64 Q8TB36,Q9NP80,Q13510,P35637,P13473,Q13126,Q8NAT1,P51114,P22626,P10253,Q99720,O60313,Q9BQT8,P12235 14 +Gastrointestinal hemorrhage 0.3795834204308178 1.037858169293435 0.2993360907130553 1.0 0.5761946299549962 29 O76024,P49257,P01889,Q6YHK3,Q9UJS0,Q9UHX1,Q9NZ08,P49327,P21964,P21912,Q9UGP8,Q14739 12 +Steppage gait 0.4196759460989624 1.036883576586224 0.2997901188327989 1.0 0.5766290980623177 21 O15269,Q15120,P31483,O15270,Q9NR77 5 +Hemiplegia hemiparesis 0.332531926168379 1.036190054212541 0.3001134858211904 1.0 0.5768834319922428 42 P42345,Q9NP80,P03886,P01889,Q9NZ08,P00403 6 +Acute hepatic failure 0.4700990639801233 1.0349654994111577 0.300685023617 1.0 0.5775679680227064 15 Q9H845,O75648,Q6NUQ1,Q96J02,P08574,P01889,A2RRP1,Q9P2J5,Q16836 9 +Urinary bladder sphincter dysfunction 0.5284758905404789 1.0341262395419033 0.3010771508914431 1.0 0.5775679680227064 9 Q9NR77,Q06787,Q12768,P22626 4 +Sporadic 0.3791681373026167 1.034120198224017 0.3010799748098112 1.0 0.5775679680227064 29 P04350,P42345,P48651,Q9BWD1,O96028,O95202,P51812,P21912,P04062 9 +Abnormality of the fetal cardiovascular system 0.6018866783587725 1.0324299897658564 0.3018707289467273 1.0 0.5785404318712359 6 P16435 1 +Thickened skin 0.2923528294109488 1.0322143667100965 0.3019717062608151 1.0 0.5785404318712359 105 O75844,Q06136,O15269,P16278,P51648,O15270,P16615,Q9NWM8,P06280,O95470,Q15800,P07437,Q14739,P04062 14 +Abnormal circulating free fatty acid concentration 0.6287215411558569 1.0319018326267628 0.3021181073757204 1.0 0.5785823276453409 4 P40939,Q16836,O75431 3 +Thickened calvaria 0.5279907883431745 1.0314870403364649 0.3023124824825063 1.0 0.5787160253867838 9 O00754,Q9Y5W7,P48651,P16278,Q8IWS0,P51812 6 +Hepatosplenomegaly 0.3235101509752904 1.0308436370082374 0.302614151201491 1.0 0.5790549202974166 46 P10619,Q96J02,P11166,O60762,P16278,P51798,Q5HYI8,Q99519,Q9UJS0,O75845,Q96HY6,Q13510,Q14739,P04062 14 +Long fingers 0.2907039820042083 1.0283356517206783 0.3037919661716879 1.0 0.5806388510892637 81 P23786,Q06136,P55795,P42892,P16435,Q9UL01,Q96L58,O96028,Q9UHX1,Q15907,P07437,P21964 12 +Posterior embryotoxon 0.4371020930413 1.02659044466966 0.3046133553101182 1.0 0.5819217305801025 18 Q7LGA3,P21964,P53701 3 +Transient ischemic attack 0.5354847129489464 1.0248100222184202 0.3054528365395739 1.0 0.5828065209703739 8 O75844 1 +Bronchitis 0.5174105469722308 1.023471117386455 0.3060851491868299 1.0 0.5837732360927799 10 Q13315,Q03518,Q03519 3 +Bile duct proliferation 0.6134306569342973 1.0224861768496796 0.3065508518010955 1.0 0.5839422949847847 5 O15078,Q5XKP0,P51659,Q9P2L0 4 +Soft skin 0.5259562670904352 1.0204231192698827 0.3075278338512057 1.0 0.585323357670095 9 Q13126,Q9NWM8 2 +Short upper lip 0.6124985390969704 1.0183026258999075 0.3085341608878476 1.0 0.5869982438513267 5 O96028 1 +Aplasia hypoplasia of the cerebellar vermis 0.2962203091294308 1.016298743409034 0.3094871468133213 1.0 0.5885703168623377 78 Q8WVX9,Q9UM00,Q15907,P98175,P23786,Q96KP1,O43683,Q12768,Q10713,Q99567,Q9Y487,P07437,Q8N201,Q6NUK1,Q13535,Q8NFH4,Q9UBM7,Q8NAT1,Q03154,Q9H490 20 +Distal upper limb amyotrophy 0.4860663028022356 1.013257901075445 0.3109369904264998 1.0 0.5907935344135928 13 Q15120,P31483,Q9BQT8,Q9NR77,O60568 5 +Aplasia hypoplasia of the femur 0.4561939260522746 1.010802308598449 0.3121110579715247 1.0 0.5923480291404019 16 Q96L58,Q96HY6,Q9UHX1 3 +Abnormal epiglottis morphology 0.6101748428554543 1.0078793514398692 0.3135123855082251 1.0 0.59430647975823 5 Q13510 1 +Impaired glucose tolerance 0.5962669197253752 1.00638034649285 0.3142326440120517 1.0 0.5951589335833642 6 O76024 1 +Pollakisuria 0.6226374077612419 1.005434424024748 0.3146877109033656 1.0 0.59553527692751 4 Q06787,Q8WVX9 2 +Scrotal hypoplasia 0.4225806098352407 1.0025121968475716 0.3160962787880501 1.0 0.5977140053924627 19 Q6NUK1,P18074,P16435,Q9UBM7,Q8IWS0,P46977,Q8TCJ2,P07437 8 +Lissencephaly 0.3203821089065688 1.0018958135692284 0.3163939147657748 1.0 0.5980334125312409 59 P23786,P42695,P11177,Q6ZXV5,O14936,Q9Y487,P78527,Q13535,Q8NAT1,Q16134,Q9NWS8,Q15392,Q16625,Q9Y320,Q86XL3 15 +Abnormal nipple morphology 0.3190414731745019 1.0011060234438536 0.3167755532746144 1.0 0.598511273084123 64 Q7LGA3,P61978,O14678,Q92974,Q9UM00,O95202,Q5SRE5,Q2TAA5,P23786,Q96KP1,Q12768,P07437,Q15067,Q6NUK1,Q9NXE4,O96028,O60762,Q9UBM7,Q96A33,Q14738 20 +Upper extremity joint dislocation 0.4019179043431523 1.0004267928621249 0.3171040091822639 1.0 0.5986449519141804 24 Q6ZXV5,Q9Y619,Q96L58,Q13535,Q96PU5 5 +Aplasia involving bones of the extremities 0.6213997794494148 1.0000575355202106 0.3172826648408966 1.0 0.598738936170108 4 Q9BXW9,Q8NCM8 2 +Cervical spinal canal stenosis 0.5631824552051967 0.9977609775364662 0.3183952766901927 1.0 0.6005945820148743 3 O43909 1 +Brisk reflexes 0.4101881366628548 0.995668525212998 0.3194112278094108 1.0 0.6022664628256991 22 Q99720,P35637,Q5JRX3 3 +Woolly hair 0.5929287990695227 0.9909322390622416 0.3217186688281626 1.0 0.6056412063151411 6 Q96A33 1 +Oral cleft 0.2760385911683367 0.9881481533560584 0.3230800956288255 1.0 0.6079506376231363 172 Q7LGA3,P61978,Q5JPH6,O95630,P78318,Q13045,Q9UM00,O95202,Q6DKJ4,Q15392,Q5SRE5,P98175,P21964,O75844,O43683,Q12768,Q10713,Q99567,Q9Y619,Q9NWM8,Q15427,P07437,Q8N201,O15360,Q9NXE4,Q9UL01,Q96L58,Q13535,Q96PU5,O96028,Q14739,Q8TAA9,P16435,P48651,O14936,Q6PGP7,Q9UBM7,Q8NAT1,Q9UHX1,Q14738 40 +Retinal coloboma 0.4916235532153933 0.9856945592733084 0.3242830201359958 1.0 0.6096869848467461 12 Q9UHX1,Q10713,Q8N201 3 +Femoral bowing 0.5279030559297061 0.9846941520635298 0.3247743261070996 1.0 0.6096869848467461 8 Q32P28 1 +Abnormal bronchus morphology 0.3676799687292618 0.984684778069207 0.3247789320217444 1.0 0.6096869848467461 30 P16435,Q13277,Q13315,Q03519,Q96HY6,Q03518 6 +Heart block 0.3676394180392048 0.98431147377385 0.3249623897467493 1.0 0.6096869848467461 30 P23786,Q9HD47,Q99959,P50402,Q14BN4,P06280,O43772 7 +Abnormal speech prosody 0.5601336484979703 0.9841278386240244 0.3250526606684008 1.0 0.6096869848467461 7 P04062 1 +Fatigable weakness of swallowing muscles 0.4912710126144938 0.9836167800327272 0.3253039714960528 1.0 0.6099121273489352 12 Q15165,Q92804 2 +Abnormal pupil morphology 0.46204423023193 0.9830699328642692 0.3255730211453536 1.0 0.6101328541861816 15 Q9NR77,O96028,P61586 3 +Coxa valga 0.412527198569022 0.9825795618131252 0.3258144074941183 1.0 0.6101328541861816 21 O75844,Q96L58,P16278,Q9Y619 4 +Abnormal labia majora morphology 0.5007342555715821 0.9823103113960276 0.3259469961450931 1.0 0.6101328541861816 11 Q9Y619 1 +Hypoplastic labia majora 0.5007342555715821 0.9823103113960276 0.3259469961450931 1.0 0.6101328541861816 11 Q9Y619 1 +Diaphyseal thickening 0.6170109116155074 0.9810110540698452 0.3265872904291049 1.0 0.6108391913581407 4 P08236,Q14739 2 +Skeletal dysplasia 0.3194035103419428 0.979772824372768 0.3271982693397817 1.0 0.6112437311429939 47 P10619,P16278,P51648,Q99519,Q96L58,Q15427,Q96HY6,Q14739 8 +Abnormal circulating pyruvate family amino acid concentration 0.4155804239528141 0.9771111293746422 0.3285141385200987 1.0 0.6130692924121504 20 Q99797,Q9Y2Z2,O96000,Q9NP80,P03886,P14854,Q9UJS0,Q5XKP0,Q9P0J0 9 +Encephalopathy 0.2883553026487504 0.9769955409744974 0.3285713599023363 1.0 0.6130692924121504 110 Q96CU9,Q7KZN9,O43676,P00403,P04062,O75306,P23786,P07602,P11166,Q86Y39,P08574,Q9Y619,Q9UJS0,Q9NVI7,Q15067,Q9Y6M9,Q9NPL8,Q6NUQ1,P03886,Q9NZJ7,O43772,P23378,Q00839,O96000,O60762,Q03154,Q16836 27 +Arterial thrombosis 0.5897649442388482 0.9763097214061222 0.3289110039120082 1.0 0.6132104832163684 6 P01889,Q9NZ08 2 +Curly hair 0.4894568669427143 0.9729299276801056 0.3305881295563666 1.0 0.6151031036919821 12 P42345,P55795,Q96A33 3 +Insulin resistant diabetes mellitus 0.5255902828762784 0.9724826955961864 0.3308104695083464 1.0 0.6151814546068846 8 O75844 1 +Abnormality of cranial sutures 0.2888652447106545 0.97089494999047 0.3316005931869354 1.0 0.6155079328591698 94 P61978,P51798,Q9UM00,P98175,P21964,O95831,O75844,Q32P28,Q9Y619,Q9Y487,Q6NUK1,Q9UL01,Q96L58,Q13535,O75845,O75718,Q00839,Q96AY3,P16435,P48651,Q9Y366,P51812 22 +Skin plaque 0.6015718812968648 0.9693709640690832 0.3323601340800755 1.0 0.6165566208404106 5 Q06136 1 +Prominent antitragus 0.5011668611435423 0.9683767824400178 0.3328562304832489 1.0 0.6165566208404106 2 Q92643 1 +Rieger anomaly 0.614079873493386 0.9683105047897568 0.3328893200054186 1.0 0.6165566208404106 4 O96028 1 +Impaired vibration sensation in the lower limbs 0.4693479613455423 0.9681419867081986 0.3329734632524965 1.0 0.6165566208404106 14 Q8TAF3,Q9NR77,Q12768,Q15120 4 +Wide intermamillary distance 0.3774691346976973 0.9675959215718302 0.3332462149249147 1.0 0.6165917620633825 28 P23786,P61978,Q96KP1,O14678,Q9UBM7,Q92974,Q9NXE4,Q9UM00,Q5SRE5,P07437 10 +Aplasia hypoplasia of the tongue 0.6004327700741481 0.9642825830232128 0.3349042705459051 1.0 0.6194129143934216 5 P48651,Q9UBM7 2 +Large for gestational age 0.5231273737403133 0.9594932854463428 0.3373103006604028 1.0 0.6231187502458178 8 P04049,Q9UM00,P42345,Q9H9B1 4 +Tremor by anatomical site 0.3764233333249682 0.9584295545768252 0.3378461981203782 1.0 0.6238606663224472 28 P04350,Q15120,Q96RL7,P35637,Q99720,Q9NR77 6 +Ectopia lentis 0.4964198484926616 0.957634732624637 0.3382469786545541 1.0 0.624352587536376 11 Q03518,Q03519 2 +Abnormality of endocrine pancreas physiology 0.5987567935356071 0.9568008557588582 0.3386677802448674 1.0 0.6245042379892783 5 Q14739 1 +Abdominal aortic aneurysm 0.611386288705768 0.9566534720780614 0.3387421898082814 1.0 0.6245042379892783 4 P01889,O15460 2 +Foot dorsiflexor weakness 0.3506100873820834 0.9549156994891844 0.3396203297782973 1.0 0.625075687865378 35 O15269,P31483,O15270,Q99720,Q9NR77,Q9BQT8,Q14739 7 +Short ribs 0.5049398437576805 0.9540041291100032 0.3400815522833311 1.0 0.625075687865378 10 Q14739,Q9Y619,Q15427 3 +Microdontia 0.3556368403322423 0.9537368293672752 0.3402168726241017 1.0 0.625075687865378 33 Q7LGA3,Q6NUK1,Q9Y366,Q9Y619,Q9Y487,P61586,Q96L58,Q9Y4P3,Q96A33 9 +Orofacial dyskinesia 0.5977996527382934 0.9525307220845428 0.3408278927973578 1.0 0.6252105214994884 5 O75569 1 +Inappropriate behavior 0.457279831278551 0.9524577487941408 0.3408648839772286 1.0 0.6252105214994884 15 Q9NZJ7,P17900,P07602 3 +Vascular dilatation 0.2918507644943169 0.950938076034166 0.3416358115896218 1.0 0.6263772615017297 78 Q7LGA3,P61978,P38435,O15460,Q9UGP8,O75844,Q9Y4P3,P10253,Q6NUK1,P42858,O75648,P55011,Q06787,Q96L58,Q96PU5,Q6ZXV5,P01889,Q96PZ0,Q96MF7,O60568 20 +Adenomatous colonic polyposis 0.5530941251128549 0.9500628114177836 0.3420803379501065 1.0 0.626697653831307 3 Q07864 1 +Flared metaphysis 0.5041027763324353 0.94935577034872 0.3424396975399246 1.0 0.626913791657394 10 P48651,Q96L58,Q14739 3 +Elevated hemoglobin a1c 0.5528760399534478 0.9490343840115532 0.3426031246272327 1.0 0.626913791657394 3 Q96MF7 1 +Aortic regurgitation 0.3806319379088749 0.9479448154819335 0.3431575484595002 1.0 0.6276810906074165 27 O75844,Q6PGP7,Q6ZXV5,P01889,Q96PU5,Q9UHX1,Q9NZ08 7 +Renal dysplasia 0.436406882966223 0.9472145409119902 0.3435294672809152 1.0 0.6280713255444431 17 O75306,O14936,Q9NWS8,O43505,Q8N201 5 +Muscle spasm 0.3166633491114924 0.9466662937347068 0.3438088511770285 1.0 0.6280713255444431 54 P23786,Q15165,P35637,P13473,P53985,P12235,Q9NR77,P04062,Q92804 9 +Tetraplegia tetraparesis 0.3164202996220598 0.9403732911381708 0.3470261173489775 1.0 0.6322497674103473 52 Q9H9P8,P51970,P17900,P51572,P07602,Q5JPH6,O95630,P35637,Q9UBX3,Q9NZJ7,Q8WVX9,Q13423,O43681,P21912,O95831 15 +Abnormality of the odontoid process 0.5511884130727553 0.9401274157370212 0.347152207633189 1.0 0.6322497674103473 7 P16278,P08236 2 +Pain insensitivity 0.6071591655768704 0.9383897719607962 0.3480441402628111 1.0 0.6335809574948899 4 O15269 1 +Gangrene 0.5020873435066613 0.9381722969592302 0.3481558726828355 1.0 0.6335809574948899 10 P01889,Q9NZ08 2 +Abnormal dlco 0.4947491248541531 0.9350860132553934 0.3497439740496757 1.0 0.6362218102720413 2 O95453 1 +Optic nerve dysplasia 0.5488295018938049 0.9299748270427748 0.3523841182209377 1.0 0.6405229316332068 3 O43505 1 +Hallux valgus 0.4327578895205898 0.9223308639871876 0.3563560197224549 1.0 0.6449669137633524 17 P04062,Q15427,Q9Y4P3 3 +Ecchymosis 0.4803700563686026 0.919548246187864 0.3578088824506109 1.0 0.6468404933328943 12 P04062 1 +Corneal dystrophy 0.5901543695442225 0.9184961117150516 0.358359193668269 1.0 0.6469452437721254 5 P12235 1 +Amniotic constriction ring 0.4915402567094578 0.918491770256875 0.3583614655384592 1.0 0.6469452437721254 2 Q9Y244 1 +Abnormality of upper limb epiphysis morphology 0.4321767278064971 0.918372624207644 0.3584238177936829 1.0 0.6469452437721254 17 P16435,Q9Y366,Q13535,O15228,O96028,O95202 6 +Impaired vibratory sensation 0.3661103847381957 0.9168813481089796 0.3592048188202881 1.0 0.6475601666775709 29 O14773,Q96RL7,Q06787,Q9Y619,Q8TAF3,Q9NR77 6 +Abnormal external genitalia 0.2532981426801018 0.9167255595886667 0.3592864689827555 1.0 0.6475601666775709 302 Q7LGA3,Q06136,P51970,P61978,O14678,Q9UBX3,Q13315,P51571,Q13423,O95202,Q6DKJ4,Q15392,Q01844,P98175,P21964,Q86XL3,O75844,Q10713,P37268,P53701,Q99567,Q9Y619,Q9Y487,P46977,Q9Y4P3,Q9NZ08,P07437,Q9NVI7,P42858,O75648,P42892,Q06787,O15360,Q9UL01,Q13535,Q96PU5,P51114,O96028,O95470,O75845,P38159,P42345,Q8TAA9,O76024,P16435,P48651,Q6PGP7,P01889,Q8NAT1,Q9UHX1 50 +Flexion contracture of digit 0.2987972080474478 0.9166888140654932 0.3593057293411417 1.0 0.6475601666775709 73 P49902,O75844,P42892,P16435,Q99567,Q9Y619,Q9UL01 7 +Areflexia 0.2849679021582033 0.9165782388572332 0.3593636918291909 1.0 0.6475601666775709 89 O15269,P10253,P61978,Q15120,Q96RL7,Q8TB36,Q8NAT1,P51114,Q9NWS8,P12235,Q13510,Q9NR77,O60313,Q9BQT8,Q14738,Q15067 16 +Bilateral tonic clonic seizure with generalized onset 0.4889874385191878 0.915256613344214 0.3600569302469125 1.0 0.6481303750202075 11 Q13510,Q9Y320,P04062 3 +Macular atrophy 0.5145841152601353 0.914567628798746 0.3604186592748331 1.0 0.6484256554975032 8 P04062 1 +Spondyloepimetaphyseal dysplasia 0.5145545546897202 0.9144125672290466 0.3605001007641091 1.0 0.6484256554975032 8 Q96L58,Q96HY6 2 +Hypertensive crisis 0.5884353868021974 0.9108629131241665 0.3623676087247265 1.0 0.6510285808720339 5 P21964 1 +Abnormality of lipoprotein cholesterol concentration 0.4408626271852802 0.9093238666344128 0.3631791960431321 1.0 0.651730608272071 16 Q15800,Q8N511 2 +Abnormal glial cell morphology 0.3133382737127427 0.9089226474924624 0.3633909582256893 1.0 0.6518588385778196 57 O75306,P42858,O75874,P42345,Q10713,P48735,P35637,Q7KZN9,Q16134,P04062,O95831 11 +Abnormality of mouth shape 0.3015884744545891 0.908468882339148 0.3636305470998309 1.0 0.6520368667795501 71 P04350,P42345,P61978,Q10713,Q8N201,Q96PZ0,O75845,O96028,O95202,Q6DKJ4,Q14738,Q96A33,O60568,P04062,Q86XL3 15 +Flared iliac wing 0.5443347562915174 0.9065540578047164 0.3646426660237878 1.0 0.6526419533108752 7 Q96L58,P16278 2 +Generalized amyotrophy 0.3807568531847419 0.9058323457580146 0.3650245977311381 1.0 0.6530243669845467 26 Q99567,P35637,P13473 3 +Macroorchidism 0.5866213305043304 0.9028157210927592 0.3666237060055426 1.0 0.6550860087333188 5 Q06787 1 +Microcornea 0.3557908229056263 0.9027512750546642 0.3666579163435766 1.0 0.6550860087333188 31 Q9H9S5,Q96L58,Q13045,O15078,Q9NWM8,O75845,Q8NAT1,O43505,P07437 9 +Abnormality of alkaline phosphatase level 0.3897290952891626 0.9025947669964984 0.3667410048892299 1.0 0.6550860087333188 24 Q96AY3,Q96A33,O75845,P22626,Q8N511,Q14739 6 +Abnormal reflex 0.2468624965367719 0.9019869613197716 0.3670637940841843 1.0 0.6554106023501616 373 P11177,Q7KZN9,Q92974,Q13045,Q99720,P04062,Q12768,P07602,Q9Y619,O43681,O75477,Q16637,P17900,P55011,P03886,P43243,Q6DKK2,P51114,Q5JRX3,P54802,P05023,O60762,O14936,O75503,O14979,Q8NAT1,Q5XKP0,P51812,Q9NR77,Q9Y320,O14949,Q9BQT8,Q9P0J0,Q86XL3,P49902,O14773,Q9NWS8,Q9NZ08,Q96N66,Q15043,O43292,Q06787,P12235,Q14739,P35637,Q13510,P35610,Q14738,Q96CU9,Q2TAA5,O15269,Q10713,Q9Y4P3,P10253,Q15067,Q9NZJ7,Q99519,P13073,O75569,Q16625,Q96AY3,Q96RL7,P01889,O60313,P61978,Q15120,Q8TB36,Q13315,O95831,O75306,P50402,P42695,P42858,O75648,O15360,P23378,Q8TAA9,Q9BT22 78 +Fetal distress 0.3849228916433215 0.9005764156841591 0.3678135788413605 1.0 0.6560233055364567 25 O75306,Q9Y6M9,Q9NPL8,Q86Y39,P03886,Q96CU9,O43676 7 +Abnormality of globe size 0.3085078864771114 0.8988562993741526 0.3687292076497077 1.0 0.6564385240765683 66 Q6NUK1,O43683,P53701,O14936,O15360,P61586,Q13535,Q8NAT1,Q9UBN7,O75569,Q9UHX1,Q5SRE5,P07437,P21964,Q8N201 15 +Bilateral cleft lip and palate 0.4874562427071361 0.8974260736029133 0.3694916046579648 1.0 0.6564657725586633 2 O60716 1 +Non midline cleft palate 0.4874562427071361 0.8974260736029133 0.3694916046579648 1.0 0.6564657725586633 2 O60716 1 +Bilateral cleft palate 0.4874562427071361 0.8974260736029133 0.3694916046579648 1.0 0.6564657725586633 2 O60716 1 +Hypolipoproteinemia 0.5110870837127743 0.8962439200511322 0.3701225033058151 1.0 0.65733530212493 8 Q15800 1 +Abnormality of the fontanelles or cranial sutures 0.2827253979699132 0.8944014937470199 0.3711071135483874 1.0 0.6579174317061052 114 P61978,P51798,Q9UM00,Q16134,P98175,P21964,O95831,O75844,Q32P28,Q12768,Q9Y619,Q9Y487,O15228,Q6NUK1,Q9UL01,Q96L58,Q13535,O75845,O75718,P42345,Q00839,Q96AY3,P16435,P48651,Q9Y366,Q9BT22,P51812,Q14738 28 +Aplasia hypoplasia of toe 0.3444810899087731 0.8941973711344653 0.3712162985564193 1.0 0.6579174317061052 35 Q7LGA3,P42858,O75648,P55011,Q96PZ0,P13073,O96028,O95202,Q15427,Q9UHX1,Q13510 11 +Abnormality of mouth size 0.2779140298203837 0.8940844872659955 0.3712766885984442 1.0 0.6579174317061052 136 Q7LGA3,P51571,Q9UM00,Q9UBN7,Q6DKJ4,Q15392,P21964,P04062,O75844,P16278,Q9Y619,Q9Y487,Q15427,Q9Y4P3,P07437,Q9NVI7,Q6NUK1,P42858,O75648,P55011,P55795,P15586,Q9UL01,P42345,P16435,P48651,Q6PGP7,Q9UBM7,Q96PZ0,P51812,Q9H490 31 +Constipation 0.2840746727517131 0.8934764978346178 0.3716020525344907 1.0 0.6579174317061052 95 Q7LGA3,P61978,P36551,P78318,Q13045,Q13423,P21964,P00403,P04062,P37268,Q9Y4P3,P55011,P55795,P42892,P03886,Q9UL01,P12235,Q8TAA9,O76024,P16435,Q9UBM7 21 +Vertebral hypoplasia 0.4758814011899854 0.8932832567665854 0.3717055020076121 1.0 0.6579174317061052 12 Q96HY6,P16278,Q6NUQ1,Q14739 4 +Puberty and gonadal disorders 0.2705996480880187 0.8919166100652861 0.3724376309623218 1.0 0.6579174317061052 174 Q7LGA3,O75874,P48735,Q13315,Q13423,P06280,O95202,P00403,P04062,O75844,Q9Y4P3,Q9NVI7,Q14108,P42858,O75648,P03886,Q06787,O15360,O96028,O95470,Q15800,O76024,P16435,P48651,Q9BT22,Q96PZ0,Q4J6C6,Q96MF7,O60313 29 +2 3 finger syndactyly 0.4862893815636136 0.8914191128935665 0.3727043678489632 1.0 0.6579174317061052 2 P14923 1 +3 4 finger syndactyly 0.4862893815636136 0.8914191128935665 0.3727043678489632 1.0 0.6579174317061052 2 P14923 1 +Hypovolemic shock 0.4862893815636136 0.8914191128935665 0.3727043678489632 1.0 0.6579174317061052 2 P14923 1 +Alopecia universalis 0.4862893815636136 0.8914191128935665 0.3727043678489632 1.0 0.6579174317061052 2 P02545 1 +Death in adolescence 0.4862893815636109 0.8914191128935532 0.3727043678489703 1.0 0.6579174317061052 2 Q8IYI6 1 +Tapered distal phalanges of finger 0.4862893815636019 0.8914191128935073 0.3727043678489949 1.0 0.6579174317061052 2 Q01082 1 +Cerebral dysmyelination 0.502089297714321 0.8913973646237241 0.3727160310483144 1.0 0.6579174317061052 9 P07602 1 +Abnormal femoral head morphology 0.396612629122298 0.8910023882020532 0.3729278890204293 1.0 0.6579906437050284 22 Q7LGA3,P16278,Q96L58,O60568,O95831 5 +Polydactyly 0.3122598894937802 0.8907920206571658 0.3730407566765055 1.0 0.6579906437050284 53 P61978,Q10713,Q12768,Q9Y366,Q9UBM7,Q99519,Q13045,O75845,O96028,O95202,Q9UHX1,P98175,P21964,Q14739,Q15067 15 +Ivory epiphyses 0.5400087150644204 0.8885911193370107 0.3742228655542172 1.0 0.6593247756408392 3 Q13535 1 +Undetectable light and dark adapted electroretinogram 0.5395389553545478 0.88639399279059 0.3754052551565738 1.0 0.6606926933306393 3 P55265,Q15555 2 +Apnea 0.2836288247618809 0.8863556767714946 0.3754258954784519 1.0 0.6606926933306393 95 P51798,Q7KZN9,Q96CU9,P98175,Q9P0J0,P04062,O75306,P23786,Q96KP1,O43683,Q10713,P07602,Q86Y39,P03886,Q9NZJ7,P51114,O43772,O76024,Q03154,P51812,Q96A33,O60313 22 +Abnormal aortic valve cusp morphology 0.3831447469474972 0.8860640789002353 0.3755829982791687 1.0 0.6607188981465422 25 P61978,P37268,Q6PGP7,Q96L58,Q6DKJ4,Q9Y4P3,Q9UHX1,Q14738 8 +Broad palm 0.5397405207756972 0.8841262982615316 0.3766280383025604 1.0 0.6618055468811255 7 Q14739,O95831 2 +Facial hemangioma 0.5822256674321898 0.8833529783154433 0.3770455880248511 1.0 0.6622887720088689 5 Q12768,P16435 2 +Optic disc coloboma 0.5939334103062383 0.8815145907590445 0.3780393602816565 1.0 0.662997709605121 4 Q10713 1 +Round face 0.4267495627832537 0.881480496484075 0.3780578057582322 1.0 0.662997709605121 17 Q32P28 1 +Abnormal nervous system electrophysiology 0.2625832829154236 0.878603071270426 0.3796165299643876 1.0 0.6646462157009513 195 Q9BQE5,Q15120,Q8TB36,Q9UBX3,O95202,P50897,Q99720,P21964,P00403,Q2TAA5,O14773,O15269,P07602,O15270,Q9Y619,Q96N66,Q14108,Q15067,O43292,P03886,Q9NZJ7,Q99519,P13073,O96028,Q96RL7,O75503,Q96A33,Q9NR77,O60313 29 +Abnormal circulating proteinogenic amino acid derivative concentration 0.386167002895916 0.8741359482512209 0.3820442226087712 1.0 0.6670339940775465 24 Q99797,Q9Y2Z2,O96000,Q9NP80,P03886,P14854,Q9UJS0,Q5XKP0,P09001,Q9P0J0 10 +Ketoacidosis 0.4902019595429772 0.8724977572623356 0.3829368911295334 1.0 0.6683413960134531 10 P53985,P35610 2 +Decreased cervical spine flexion due to contractures of posterior cervical muscles 0.5663886167890629 0.8689853964755248 0.384855118425961 1.0 0.6711676945130352 6 P50402,Q8WXH0 2 +Abnormal renal tubule morphology 0.376298077173142 0.8686687748147262 0.3850283251739401 1.0 0.6711676945130352 26 P03886,P23786,P06280,Q9Y4P3 4 +Limb dystonia 0.4346522516043313 0.868475443733193 0.385134109679671 1.0 0.6711676945130352 16 O75569,Q99720,P35637,Q96RL7 4 +Radial bowing 0.5780656828072057 0.8649842585753983 0.3870474287534375 1.0 0.673491518347742 5 Q32P28 1 +Abnormal size of the clitoris 0.4138791845948072 0.8628692659444667 0.3882093503729966 1.0 0.6750077252368797 18 P53701,P16435,P40855,Q9Y619,Q9UBM7,Q13535 6 +Congestive heart failure 0.3085031119798152 0.8597055041031654 0.3899513999460093 1.0 0.6767703414826893 63 P03886,P16278,Q70HW3,P06280,Q9Y4P3,P10253,P07437,Q00325,P00403,P22626 10 +Bilateral cryptorchidism 0.4960250618286033 0.8589062938940081 0.3903922167275853 1.0 0.6767891679313656 9 P48449,P78318,P27635,P37268 4 +Urinary urgency 0.4958519721742433 0.8579810625540484 0.390902920472804 1.0 0.6774095369327294 9 P54886,Q12768,P04062,Q8WVX9 4 +Abnormality of bladder morphology 0.4787186700880361 0.8570331894442579 0.3914265424700716 1.0 0.6777306347003107 11 Q9NWM8,P16435 2 +Ichthyosis 0.338062087054383 0.8570066067754412 0.3914412333450263 1.0 0.6777306347003107 36 Q15800,O95470,P04062 3 +Centrally nucleated skeletal muscle fibers 0.576220538013138 0.856853536855467 0.3915258337356078 1.0 0.6777306347003107 5 P51114 1 +Supraventricular tachycardia 0.503428698039699 0.8562691989211246 0.3918488941752183 1.0 0.6780372299210666 8 Q9HD47,Q99959 2 +Failure to thrive 0.2476652802270496 0.8554870054124948 0.3922815952543068 1.0 0.6781436729575252 315 P51970,O95630,Q96CU9,Q7KZN9,Q13315,P51571,Q13423,O43676,O95202,Q15392,Q99707,P98175,P21964,Q9BQT8,Q9P0J0,P00403,O75844,P04062,Q2TAA5,Q99797,O75306,P07602,P37268,P53701,Q86Y39,Q9Y619,Q9Y487,P46977,O15228,Q9Y4P3,P10253,Q96EY8,Q15067,Q9Y6M9,Q9NPL8,P55795,P42892,P03886,Q06787,Q9NZJ7,Q96L58,P13073,O75845,O96028,Q00325,Q15800,P12235,Q16625,Q14739,Q9Y2Z2,P48651,Q6PGP7,Q14376,Q15904,Q4J6C6,Q13510,Q8N5M9 57 +Restrictive cardiomyopathy 0.532827545958578 0.8550864273922404 0.3925033028809122 1.0 0.6781592953457486 3 Q969N2,O95235 2 +Premature graying of hair 0.4869235992923728 0.8544774766173423 0.3928404839171073 1.0 0.6782374166773991 10 Q13126 1 +Abnormality of blood circulation 0.2991858019763562 0.8531218223424029 0.3935917509680724 1.0 0.6787043451827615 70 O75844,P23786,O76024,P38435,Q13277,P05067,Q9Y487,P49257,P01889,Q6YHK3,Q9UJS0,Q14739,Q9UHX1,Q9NZ08,P21964,P21912,Q9UGP8,P04062 18 +Autoamputation 0.5628317742369817 0.8527889317480657 0.3937763629262711 1.0 0.6787043451827615 6 O15269 1 +Aplasia hypoplasia of the ribs 0.3694555767603274 0.852606482246071 0.3938775666336693 1.0 0.6787043451827615 27 Q8TAA9,Q9Y619,Q96L58,Q13535,Q15427,Q9UHX1,Q96HY6,Q14739 8 +Cerebral cortical hemiatrophy 0.4787047841307018 0.8525129109330674 0.3939294762199896 1.0 0.6787043451827615 2 Q9H9B1 1 +Dilated fourth ventricle 0.3084331250006737 0.8503053060871402 0.3951553673151311 1.0 0.6797081956853385 47 P23786,Q10713,Q12768,O43683,O14936,Q99567,Q9UBM7,Q9Y487,Q8WVX9,Q8NAT1,P07437 11 +Unexplained fevers 0.5620786020044246 0.849364577188926 0.395678457518152 1.0 0.6803560746222554 6 P07602 1 +Aplasia hypoplasia affecting bones of the axial skeleton 0.2612399720266073 0.8483942353296422 0.3962184520184468 1.0 0.68078066866779 255 Q7LGA3,Q8TD16,O14678,Q13045,Q9Y4W2,Q9UM00,Q9UBN7,P51571,O95202,Q15392,Q6DKJ4,P98175,P21964,P08236,P04062,Q86XL3,O75844,O95831,Q15022,O43683,Q12768,P37268,P53701,Q99567,P16278,Q9Y619,O15228,Q15427,Q9Y4P3,P07437,Q9NVI7,Q8N201,Q6NUK1,P42858,O75648,P55011,P55795,Q6NUQ1,O15360,Q9UL01,Q96L58,Q13535,Q96PU5,O96028,O75845,Q16625,Q14739,Q8TAA9,Q00839,P16435,O60762,O14936,P48651,Q9UBM7,Q9BT22,Q96PZ0,Q9UHX1,Q96HY6,Q96MF7 59 +Impaired distal vibration sensation 0.5741776616400998 0.8478639654090558 0.3965137347530265 1.0 0.680784483245588 5 Q06787,P54886 2 +Abnormal waist to hip ratio 0.5616480860336994 0.8474080571111683 0.3967677151100035 1.0 0.6807971181900366 6 O76024 1 +Pseudoepiphyses of the metacarpals 0.5739486409410428 0.8468570062001209 0.3970748291311801 1.0 0.6809928594106543 5 P51812,O96028,O95202 3 +Abnormal conjunctiva morphology 0.368739697193178 0.8465258471953444 0.3972594610281954 1.0 0.6810581018217697 27 P10619,P01889,P06280,Q9NZ08,Q13510,Q14739 6 +Abnormal metatarsal morphology 0.3734180644212256 0.8447300649888607 0.3982615692329996 1.0 0.6822725850503378 26 P16435,Q96L58,Q8NAT1,O96028,Q15392,P08236 6 +Bone fracture 0.560674243685048 0.8429846568706963 0.3992370248622641 1.0 0.6828852739025442 6 Q13126 1 +Abnormal cerebral ventricle morphology 0.2606208378234543 0.8427752897954717 0.3993541302611305 1.0 0.6828852739025442 258 Q8TD16,P51970,P11177,P51798,Q96CU9,Q8WVX9,Q13045,Q9UM00,Q9UBN7,O95202,Q15392,Q5SRE5,P21964,P08236,P04062,Q86XL3,O75306,P23786,Q96KP1,O43683,Q12768,P07602,P53701,Q10713,Q99567,P16278,Q9Y487,Q15427,P42695,P07437,Q6NUK1,P42858,Q9NPL8,O15360,Q9NZJ7,Q9UL01,Q99519,Q96L58,O96028,Q16625,O00584,P42345,Q8TAA9,Q00839,P05023,P16435,O60762,O14936,Q6ZXV5,Q96RL7,P48651,Q9UBM7,P14854,Q8NAT1,Q13885,Q9UHX1,P51812,Q9H490,Q9Y320,Q14738 60 +Multifocal cerebral white matter abnormalities 0.5604937295517584 0.8421650792039804 0.3996955575592507 1.0 0.6831436212824037 6 Q9Y619 1 +Abnormality of exocrine pancreas physiology 0.3997654037236794 0.8364054651247119 0.4029268391216001 1.0 0.6872172827907235 19 Q15904,P09601,Q9UJW0,Q9UHX1 4 +Loss of ability to walk 0.4297011572115232 0.8360469803986191 0.4031284738029725 1.0 0.6872172827907235 16 Q9H9S5,Q99519,P21912,Q96D71,Q96RR1 5 +Enlarged thorax 0.4097815360403702 0.8342382909668526 0.4041467177339846 1.0 0.6882938601877171 18 O75844,Q32P28,Q14739 3 +Abnormality of the basal ganglia 0.2795109339420572 0.83334390494341 0.4046508014286956 1.0 0.6883953216542364 88 O75306,P23786,Q96RL7,P03886,P16278,Q96CU9,Q96N66,Q13535,Q9P0J0,O60313,P00403,P04062,O95831 13 +Cardiac arrest 0.3294422743801697 0.8326373971820784 0.4050492610300367 1.0 0.6888209614734812 38 Q9HD47,Q99959,O15460,P50402,P01889,Q9Y4P3,O43772,P04062 8 +Prolonged partial thromboplastin time 0.5575993108458815 0.8290392681015094 0.4070821874137489 1.0 0.6912660243875283 6 O60762,P38435,P28288 3 +Aplasia hypoplasia of the cerebral white matter 0.4979458844852462 0.8277951302970714 0.4077865330114951 1.0 0.6922090728430422 8 P00403 1 +Brittle hair 0.4185596201230445 0.8260903313834899 0.4087528519197865 1.0 0.6933427345817189 17 O75844,Q6PGP7,Q9NVI7,Q9Y487 4 +Pediatric onset 0.2621035177965503 0.8253846483488168 0.4091532477434447 1.0 0.6935155012827597 227 P51970,Q8TB36,Q5JPH6,Q9NP80,P51798,Q96CU9,Q8WVX9,Q70HW3,P06865,P06280,Q9H0U3,Q99707,P35658,Q9P0J0,Q2TAA5,O95831,P23786,Q9H9P8,O14773,Q96KP1,Q99797,P07602,Q10713,P11166,O75306,P16278,P49770,P78527,P28288,P50402,P22830,Q9NVI7,Q15067,O75746,O43292,Q9Y6M9,P55795,Q9NPL8,O75648,Q6NUQ1,Q9NZJ7,Q5JRX3,P54802,Q14566,O00584,P42345,Q00839,O60762,Q6ZXV5,Q15904,O15118,O76031,Q5XKP0,Q13510,Q9NR77,Q9Y320 56 +Arthropathy 0.5565655841068297 0.824358702885799 0.4097357726031214 1.0 0.6939965000051412 6 O15269 1 +Breathing dysregulation 0.5803484612567269 0.8235984747474168 0.4101677429103119 1.0 0.6942219794394568 4 O15078,Q10713 2 +Macrogyria 0.5270052261304222 0.8223361858456805 0.4108855873969661 1.0 0.6951836995798633 7 Q15392 1 +Abnormal labia morphology 0.3973403713665314 0.8189113011048359 0.4128370217003692 1.0 0.6979770024817741 19 Q9Y619 1 +Abnormality of the vertebral endplates 0.4959180988670998 0.8172978271788638 0.4137582481908191 1.0 0.6988176175746029 8 Q96L58,O15228 2 +Retinal degeneration 0.3051636491685293 0.8164934044516382 0.4142179942657056 1.0 0.6990915779766195 63 Q7LGA3,P42858,O14773,O75648,Q10713,Q9UG56,O75503,P51648,P04439,P50897,Q13510,O60313,P04062 13 +Back pain 0.3788129719052717 0.8156327442841538 0.4147102158047455 1.0 0.6991087309974049 24 Q8TAA9,P36551,P54886,P51798,Q5HYI8,Q8WVX9,P50402,P01889,Q9UGP8 9 +Abnormal thyroid hormone level 0.4714119019836785 0.8153541745405999 0.414869607124448 1.0 0.699123755785341 2 O14654 1 +Thenar muscle atrophy 0.5240586889984954 0.8144357374168887 0.415395372567652 1.0 0.6996654654250055 3 O60568 1 +Serositis 0.3901271194749597 0.8137868713409646 0.4157670574386842 1.0 0.6998745466884518 21 Q92621,Q12769,Q8NFH4,O15460,P01889,O43707,Q9NZ08,P49327,Q8N1F7 9 +Fatigable weakness of bulbar muscles 0.4443115661483802 0.8131355999189084 0.4161403175540084 1.0 0.700249154420834 14 Q15165,Q92804 2 +Decreased circulating cortisol level 0.4949377683168363 0.8122297807931621 0.4166597941215859 1.0 0.7005546471466715 8 Q13423 1 +Pneumothorax 0.5248455304064085 0.8119197739249482 0.4168376672219502 1.0 0.7005546471466715 7 Q96L58,Q9UL01 2 +Perisylvian polymicrogyria 0.565860895862742 0.8114106477200018 0.4171298864697368 1.0 0.7005546471466715 5 P42345 1 +Paroxysmal bursts of laughter 0.4705367561260243 0.8109132677434486 0.4174154804227525 1.0 0.7006186134552415 2 Q05086 1 +Chronic sinusitis 0.5243744111622591 0.8096501329460004 0.4181412860531175 1.0 0.7015833929226377 7 Q03519 1 +Ketosis 0.3927542792945681 0.8083387169981838 0.4188956201290748 1.0 0.7021188208308226 20 P08574,P14854,P53985,P12235,P35610 5 +Disproportionate tall stature 0.3454173910702436 0.806478210860066 0.4199671666496669 1.0 0.7032387562670279 31 Q7LGA3,P42858,O75648,P16435,Q9UL01,Q96PZ0,Q9NWM8,O96028,O95202 9 +Central nervous system cyst 0.3045534134714248 0.806216443034498 0.4201180592894995 1.0 0.7032387562670279 62 P23786,O43683,Q12768,P11177,Q99567,Q9UBM7,Q9Y487,Q8WVX9,Q8NAT1,O96028,O95202,Q9UHX1,P07437 13 +Iron deficiency anemia 0.5646436963418382 0.8060961222178679 0.4201874273347545 1.0 0.7032387562670279 5 P28288,P49327,O76031 3 +Tapered finger 0.3118897757851744 0.8057701299255687 0.4203754040841563 1.0 0.7033000098577566 42 Q06136,Q9UL01,P42892,P23786 4 +Degeneration of the lateral corticospinal tracts 0.5642632310019238 0.8044360708017083 0.4211451763145364 1.0 0.7040216766142965 5 P35637 1 +Preaxial hand polydactyly 0.4772575808473375 0.8016298313726329 0.4227671161726152 1.0 0.7053696609595268 10 O15078,O96028,O95202,Q9UHX1,O43909,Q9P2L0 6 +Increased muscle lipid content 0.4851903922671773 0.801248361605506 0.4229878787763037 1.0 0.7053696609595268 9 P23786 1 +Abnormality of the antitragus 0.5210832989714775 0.8007147478444404 0.4232968027481969 1.0 0.7053696609595268 3 Q92643 1 +Shoulder dislocation 0.5744627426103222 0.7986934666970438 0.4244681760212332 1.0 0.7065851471854709 4 Q96PU5 1 +Anarthria 0.550774176476507 0.7982103212018836 0.4247484489210904 1.0 0.7067984576244221 6 Q99720 1 +Congenital bilateral hip dislocation 0.4679113185530992 0.7976153416946394 0.4250937453153662 1.0 0.7071197782796963 2 Q02809 1 +Hypoplasia of the brainstem 0.3471036871037252 0.7964088342474737 0.4257944451144415 1.0 0.7080318511101272 30 Q96KP1,Q10713,P11177,Q6ZXV5,O14936,Q9UPT5,Q9NXE4,Q9UNW1,Q13885,Q96EK5,P07437,Q9Y320 12 +Malignant neoplasm of the central nervous system 0.3718030498829937 0.7939812897773229 0.4272063237794623 1.0 0.7101254312269702 25 O75874 1 +Increased circulating antibody level 0.4034488893745352 0.790200122513796 0.4294109045054004 1.0 0.7112452985141142 18 P04062 1 +Radioulnar synostosis 0.3830503147008957 0.7874298872413795 0.4310302567545534 1.0 0.7124036189546976 22 P16435,Q96L58,O96028,Q15427,Q9Y4P3 5 +Mask like facies 0.4662449026140055 0.7869483932353563 0.4313120768914533 1.0 0.7126158994444141 11 P04062 1 +Abnormal venous morphology 0.3565656398695559 0.7855586202501694 0.432126114869485 1.0 0.7130346953341639 28 P98175,P21964,Q9Y487,P04062 4 +Dilatation of the cerebral artery 0.4481800135810688 0.7852107287144454 0.4323300261203093 1.0 0.7130346953341639 13 P10253,P38435 2 +Synostosis involving digits 0.5598465460636407 0.785205795682277 0.432332917941528 1.0 0.7130346953341639 5 P48651,Q9H1A4,O95613 3 +Progressive inability to walk 0.378789551397578 0.7837161299275013 0.4332066957842624 1.0 0.7133593966200317 23 Q96RL7,Q9H9S5,Q99519,Q96RR1,P21912,P54886,Q96D71,Q15043 8 +Abnormal peripheral nervous system morphology 0.2675862076226983 0.7828635181276078 0.4337072628091087 1.0 0.7133593966200317 167 Q15120,Q8TB36,Q8TAF3,Q99720,Q9BQT8,P00403,O15269,P07602,O15270,Q9Y619,Q15067,Q15043,P03886,Q9NZJ7,Q99519,Q6DKK2,P22626,P12235,Q96RL7,P48651,P35637,Q9UHX1,Q8IV08,Q13510,Q9NR77,O60313 26 +Functional abnormality of male internal genitalia 0.3354507721560306 0.7818119077011263 0.4343251219404342 1.0 0.7137865286647533 34 P16435,O15360,Q13315,Q13423,Q9Y4P3,P04062 6 +Abnormality of the clitoris 0.3822101530691887 0.7810574141320034 0.4347687272959659 1.0 0.7142629091290869 22 P16435,Q9Y619,P53701 3 +Oculomotor apraxia 0.3608038340557379 0.7793866508454038 0.4357519850040683 1.0 0.7153723400455482 27 O43292,O14773,P05067,P04062 4 +Hyperostosis 0.4298321254422169 0.7779619327363132 0.4365914552578758 1.0 0.7159914935150339 15 Q96L58,P22626,Q15043 3 +Prenatal maternal abnormality 0.4297406352989698 0.7773872700744207 0.4369303206457988 1.0 0.7160335055144768 15 O43772,Q14739,P16435 3 +Pulmonary embolism 0.5580325536768965 0.7773300517605654 0.4369640692622651 1.0 0.7160335055144768 5 Q9NZ08 1 +Symptomatic seizures 0.517561308914342 0.7769377537647122 0.4371954956487234 1.0 0.7160335055144768 7 P53985,Q13423,Q16836 3 +Abnormality of the liver 0.2462009510539133 0.7766699557205271 0.4373535169214955 1.0 0.7160335055144768 310 P61916,Q96CU9,P51798,Q7KZN9,O43676,O95202,Q01844,Q16134,Q8N511,Q9H0U3,P21964,P08236,P04062,O75306,P23786,Q10713,P07602,Q86Y39,P16278,Q9Y619,Q9UJW0,Q9NWS8,Q9Y4P3,P10253,P22830,Q96EY8,P09601,Q14108,Q9NVI7,Q15067,Q9Y6M9,Q9NPL8,O75648,Q6NUQ1,P03886,O15360,P00374,P15586,Q9NZJ7,Q99519,O75845,O96028,P54802,P12235,P22626,Q16625,O43772,Q14739,Q9BW92,P10619,Q96RL7,Q6PGP7,Q14376,Q15904,Q5HYI8,Q9BT22,O15118,Q96MF7,Q96HY6,Q96A33,Q13510,P35610 62 +Skin pit 0.4382805752676668 0.7762671806245491 0.4375912468458378 1.0 0.7160335055144768 14 P61978,O96028,P16615 3 +Abnormal cerebral artery morphology 0.3912544172117579 0.7751911561045832 0.4382267132889696 1.0 0.7161407367665055 19 P10253,P38435,P05067 3 +Intracranial hemorrhage 0.3597795327491842 0.7707606411678705 0.4408488204751268 1.0 0.7191763027509399 27 O75844,P23786,P04062 3 +Deep palmar crease 0.4543532376554053 0.7685869411945898 0.4421385602422334 1.0 0.7207634213633041 12 P42345,P98175,P61978,Q9Y487 4 +Decreased absent ankle reflexes 0.44532577926755 0.7683118365934465 0.4423019441685705 1.0 0.7207768616650924 13 Q15120,Q96RL7,Q15041,P12235,O60313,P54886 6 +Metaphyseal widening 0.3837696720489043 0.7664503725902859 0.4434083701508942 1.0 0.7222015044831156 21 P48651,P16278,Q96L58,Q96HY6,Q14739,O95831 6 +Orthostatic hypotension 0.4187537203514672 0.7648653980326687 0.4443517002180472 1.0 0.7229521687695124 16 P07602,P04062 2 +Synostosis involving bones of the upper limbs 0.3378574948714796 0.7637146979207963 0.4450372799571256 1.0 0.7229521687695124 32 P16435,P48651,Q96L58,O96028,O95202,Q15427,Q9Y4P3 7 +Insulin resistance 0.4090867458478676 0.7625441942865349 0.44573527691162 1.0 0.7237461477615744 17 O75844,Q96MF7,O76024 3 +Capillary malformation 0.4443205424758887 0.7623726970421878 0.445837596834616 1.0 0.7237461477615744 13 P42345,Q9UHX1,Q9Y4P3 3 +Status epilepticus 0.301539178372453 0.7605738066064088 0.4469116697490847 1.0 0.7247516152385612 53 O43292,P07602,P53701,P42892,Q9Y487,Q9NZJ7,Q15392,Q13510 8 +Rimmed vacuoles 0.4180862043981926 0.7605515582421497 0.4469249629053977 1.0 0.7247516152385612 16 P50402,O14979,P31483,P22626 4 +Abnormal meningeal morphology 0.3631171652372614 0.7596304296717631 0.4474755246429818 1.0 0.7253912377848197 26 Q8TAA9,Q10713,O75845,Q9UHX1,P21964,Q14738 6 +Abnormal heart valve physiology 0.2755924007586131 0.7585207605539852 0.4481392894655365 1.0 0.7259606481369884 95 P06280,P04062,O75844,O75306,O43683,Q12768,P53701,P16278,Q9Y4P3,Q9NZ08,Q9UL01,Q96L58,Q96PU5,Q6PGP7,Q6ZXV5,Q15904,P14854,P01889,Q9UHX1 19 +Abnormality of urine homeostasis 0.2577682343152186 0.7564273931249401 0.4493929893167059 1.0 0.7272908285143274 201 O14678,P36551,P48735,O15460,P53985,Q13423,P06280,Q16134,Q99707,P08236,P00403,P04062,Q9BQT8,P23786,Q9H9P8,P16278,Q9Y619,P00367,P49257,Q9UJS0,Q9Y4P3,P10253,Q96EY8,P09601,Q14108,Q6YHK3,P21912,Q9NVI7,Q02978,P03886,P15586,Q99519,O95470,P54802,P12235,O43772,P23378,Q8N1F7,Q9UBS4,Q92621,Q86YH6,P05023,O96000,P52429,O14936,Q8NFH4,Q12769,Q6PGP7,Q14376,P01889,Q96MF7,Q5XKP0,Q4J6C6,Q16836,P35610 55 +Retinal vascular tortuosity 0.4263457201041722 0.7561044370669787 0.4495865818969324 1.0 0.7272908285143274 15 P03886,P21964,Q9Y4P3 3 +Deep plantar creases 0.540656744742516 0.7528595515939895 0.4515343165378462 1.0 0.7296794555251596 6 P42345,Q9Y487 2 +Ventriculomegaly 0.2576639564193207 0.7517869355965195 0.4521791997901458 1.0 0.7302136121741459 202 Q8TD16,P51970,P11177,Q96CU9,Q8WVX9,Q13045,Q9UM00,O95202,Q15392,Q5SRE5,P04062,Q86XL3,O75306,P23786,O43683,Q12768,P07602,Q10713,Q99567,P16278,Q9Y487,P42695,P07437,P42858,Q9NPL8,O15360,Q9NZJ7,Q9UL01,O96028,Q16625,O00584,P42345,Q00839,P05023,Q96RL7,O60762,O14936,Q6ZXV5,Q9UBM7,P14854,Q8NAT1,Q13885,Q9UHX1,P51812,Q9Y320,Q14738 46 +Vocal cord paralysis 0.3878178170428581 0.750632336024391 0.452873954978636 1.0 0.7305858397794439 19 Q02978,Q8TB36,P43243,P50402,Q9NR77,P21912 6 +Upper limb amyotrophy 0.4072982521284832 0.7506198849904792 0.4528814504013772 1.0 0.7305858397794439 17 Q15120,P31483,Q9BQT8,Q9NR77,O60568 5 +Abnormality of the pancreas 0.2783240624657952 0.7499170886156532 0.4533046417490498 1.0 0.7310147051600435 78 Q6PGP7,P03886,Q15904,Q5HYI8,P53985,P01889,Q9UJW0,Q9UHX1,Q01844,Q9NZ08,Q96MF7,P09601,P00403,Q14739 14 +Olivopontocerebellar hypoplasia 0.5513432166307124 0.7484069403339719 0.4542147375488485 1.0 0.7319742180547868 5 Q9UNW1,P30153 2 +Abnormal mitochondrial morphology 0.4665687574639535 0.7437656957371408 0.4570182369270523 1.0 0.7356747547610527 10 Q00325 1 +Abnormal circulating acetylcarnitine concentration 0.51029030812502 0.7422722855537103 0.4579223798902658 1.0 0.7364165375459242 7 Q9H845,P23786,Q16836,O43772 4 +Aplasia hypoplasia affecting the eye 0.2745515948965835 0.7415341078777009 0.4583696590908901 1.0 0.736625885899784 107 Q7LGA3,P61978,Q9UBN7,O95202,Q5SRE5,P21964,Q96KP1,O43683,P37268,P53701,P11166,Q9Y4P3,P07437,Q9NVI7,P21912,Q8N201,Q6NUK1,O15360,P61586,Q99519,O96028,O75569,Q00839,O14936,Q9UBM7,Q8NAT1,Q9UHX1 27 +Abnormality of the anus 0.2995525551106527 0.7386170007139075 0.4601395979477491 1.0 0.7389590639700112 50 Q15022,Q8TAA9,Q12768,P53701,P16435,P48651,O15360,P16615,Q6DKJ4,P21964 10 +Abnormal caudate nucleus morphology 0.4646511306344745 0.7334576572747412 0.4632793442311553 1.0 0.7429740536064714 10 O75306,Q96RL7 2 +Vertical supranuclear gaze palsy 0.4562484077995813 0.7314141159756139 0.4645262456843984 1.0 0.7442836461970745 11 Q96RL7,O15118 2 +Irregular vertebral endplates 0.5357930901469139 0.7312235933746389 0.464642591373841 1.0 0.7442836461970745 6 O15228 1 +Pectus excavatum 0.2727881829462734 0.7287766314182638 0.4661383083671551 1.0 0.7459139017757368 88 Q7LGA3,P61978,P07437,Q96A33,Q06787,Q9Y487,Q96L58,P50402,Q9UHX1,Q9Y4P3,Q6DKJ4,O75718,P98175,P04062 14 +Increased sulfur amino acid level in urine 0.5073163453403242 0.7281731664151307 0.4665075897283963 1.0 0.7460909679442786 7 Q99707,O14678 2 +Purpura 0.3750123757175082 0.7267184531541432 0.4673984467913703 1.0 0.7470412737651498 22 P38435,P21964,P04062,Q99519 4 +Calvarial skull defect 0.5065067819418833 0.7243435993176859 0.4688548164356114 1.0 0.7477339475605277 7 O96028,Q14739 2 +Knee flexion contracture 0.349087898779081 0.7212999384839295 0.4707249948232737 1.0 0.7501259513165741 28 Q7LGA3,P23786,Q8TD16,P49902,Q96AY3,P37268,O60762,P48651,O75477,P21912,Q86XL3 11 +Meningocele 0.4459371255519891 0.720568723132743 0.4711749029937886 1.0 0.7501982862608436 12 P21964,O75845,Q10713 3 +Nuclear cataract 0.5554870887839939 0.7193243397059218 0.4719411024778952 1.0 0.7509767975218181 4 Q99797,P08670 2 +Abnormality of the ureter 0.2847850838279354 0.7191858252755715 0.4720264318915121 1.0 0.7509767975218181 73 Q7LGA3,O75844,P23786,P61978,Q8TAA9,Q00839,O76024,P16435,O14936,O95630,O15360,Q13045,Q9UHX1,P42695,P21964,Q9Y4P3,Q86XL3 17 +Tall stature 0.2980262123500745 0.7189872450277394 0.4721487786399549 1.0 0.7509767975218181 56 Q7LGA3,P04350,P42858,Q15022,P61978,O75648,P16435,Q9UL01,Q96PZ0,Q13423,Q9NWM8,O96028,O95202 13 +Ambiguous genitalia 0.369991650334073 0.7160034939286818 0.473989191508958 1.0 0.7533300249272133 23 Q8TAA9,O43683,P53701,P16435,O75845,Q15392 6 +Trismus 0.5541518668969392 0.7137991841042284 0.4753513642671392 1.0 0.754005612285807 4 P04062 1 +Hyperreflexia 0.2563486703127309 0.7117176344326889 0.4766396454766946 1.0 0.7552587780834089 248 Q8TD16,Q96CU9,Q7KZN9,Q8WVX9,Q99720,O14949,Q9BQT8,P04062,Q9P0J0,P49902,Q86XL3,O14773,Q2TAA5,Q10713,Q12768,P07602,O95831,P11166,O75306,Q9Y619,O43681,Q9Y4P3,P42695,Q9NZ08,O75477,Q96N66,P21912,Q15043,O75746,Q15067,P17900,O43292,P55011,P82663,P42858,P03886,P43243,O15360,Q15041,Q99519,Q9NZJ7,Q6DKK2,P13073,Q5JRX3,O75569,Q16625,P23378,Q14739,Q6P2Q9,Q9P032,O60762,O14936,O75503,P40855,P35637,P01889,Q5XKP0,Q9NR77,O60313,Q9Y320 60 +Profound sensorineural hearing impairment 0.5534228844043528 0.7107862628506029 0.4772166945323661 1.0 0.75567442494798 4 Q9NR77 1 +Morphological abnormality of the corticospinal tract 0.4351839923519678 0.7087172228904011 0.4784999747923715 1.0 0.7571903552061846 13 Q13045,P35637,P11177,Q9Y4P3 4 +Hemoptysis 0.5527622137809516 0.7080579067683027 0.4789092980834355 1.0 0.7575800472916722 4 Q9NZ08 1 +Abnormality of iron homeostasis 0.5417310569297282 0.7072044594463851 0.4794394276844169 1.0 0.7579773735806508 5 Q6PGP7 1 +Aplasia hypoplasia of the extremities 0.2548180447016467 0.707128280099392 0.4794867630119528 1.0 0.7579773735806508 195 Q7LGA3,O75874,P38435,O95630,P48735,P51798,Q9Y4W2,Q9UBN7,O95202,Q6DKJ4,Q15392,P98175,O95831,O75844,Q32P28,Q9Y619,O15228,Q15427,Q6NUK1,P42858,O75648,P55011,Q06787,O15360,Q96L58,Q13535,P13073,O96028,O75718,Q14739,P42345,Q96HY6,Q96AY3,P16435,O60762,O14936,P48651,Q9Y366,Q9UBM7,Q96PZ0,Q9UHX1,P51812,Q96A33,Q13510 44 +Diabetes insipidus 0.4263397610887658 0.7040064271945923 0.4814287710393894 1.0 0.7595294102441019 14 P01889,P06280,O15460 3 +Cerebral white matter atrophy 0.3681158923771299 0.7016670614427158 0.4828868191545097 1.0 0.76050581755656 23 Q9BYI3,P51970,Q9H9P8,P51572,O75503,Q8WVX9,O60313,P54886,Q2TAA5 9 +Multiple joint contractures 0.371613007569769 0.7012304644787526 0.4831592007342977 1.0 0.7606769388720933 22 O75844,Q99567,Q15043 3 +Hypointensity of cerebral white matter on mri 0.528892892336266 0.7007315258966513 0.4834705777572781 1.0 0.7609093171613529 6 P07602 1 +Proptosis 0.296260443115573 0.6993557924063147 0.4843297078525284 1.0 0.76200332634028 61 O75844,Q32P28,P61978,P16435,O15360,Q96L58,O96028,O95202,Q6DKJ4,O75718,O60568,Q15043 12 +Restlessness 0.3095113267172437 0.698334835619588 0.4849678185220396 1.0 0.7625134687403795 40 P42892,Q15165,P35637,P05067,P04062,Q92804 6 +Cutaneous syndactyly 0.450231837039867 0.6983118344705719 0.4849821997692254 1.0 0.7625134687403795 11 Q9Y619 1 +Generalized hyperpigmentation 0.4247464389153206 0.6944482988168811 0.487401113251527 1.0 0.7645703025606582 14 P51648 1 +Bulbar palsy 0.4412797352012501 0.6942143212043073 0.4875478127256105 1.0 0.7645703025606582 12 P35637,O43681,P31483 3 +Abnormal midbrain morphology 0.4717983455225205 0.6941200398064253 0.4876069320893736 1.0 0.7645703025606582 8 P04062 1 +Hyperacusis 0.471650999040849 0.6933785642438085 0.4880720108610945 1.0 0.7647916787377063 8 P17900,Q9Y4P3 2 +Lower limb hypertonia 0.457078612307968 0.6929957627838558 0.4883122106175697 1.0 0.7647916787377063 10 P21912,P54886,Q14739,Q8WVX9 4 +Cystic hygroma 0.4492335916950583 0.6928454165355438 0.4884065671146738 1.0 0.7647916787377063 11 Q99567,Q14739 2 +Persistence of primary teeth 0.4712189947157945 0.6912055089933029 0.4894364023584736 1.0 0.7658869184000634 8 O75844 1 +Aortic dissection 0.5485900863618498 0.6908784406031394 0.4896419357341544 1.0 0.7658869184000634 4 P01889 1 +Hyperaldosteronism 0.4463243873979203 0.689895441014027 0.4902599430308987 1.0 0.7658869184000634 2 Q01968 1 +Increased circulating androgen concentration 0.44632438739792 0.6898954410140249 0.4902599430309 1.0 0.7658869184000634 2 O14802 1 +Abnormal urine hormone level 0.4463243873979041 0.6898954410139472 0.4902599430309489 1.0 0.7658869184000634 2 P10644 1 +Increased urinary cortisol level 0.4463243873979041 0.6898954410139472 0.4902599430309489 1.0 0.7658869184000634 2 P10644 1 +Fatty replacement of skeletal muscle 0.4637157497279552 0.6888586983286974 0.4909121926209332 1.0 0.7664271486863549 9 P51114 1 +Abnormal intestine morphology 0.2550001368010507 0.6880224822874228 0.4914386236958226 1.0 0.7666970603394196 204 P61978,O14965,P06280,O95202,Q15392,Q01844,P98175,P21964,P00403,O75844,P08183,O43683,Q10713,P53701,Q99567,Q13277,Q9UJW0,Q15427,Q9Y4P3,Q9NZ08,P09601,P42892,P03886,O15360,Q9UL01,O96028,Q14566,Q14739,P42345,Q8TAA9,O76024,Q6PGP7,Q5HYI8,Q9BT22,P01889,Q96A33 36 +Aplasia hypoplasia involving the pelvis 0.4067331083151365 0.6877318050360139 0.491621687493466 1.0 0.7667251964063924 16 Q96L58,Q96HY6,O96028,O95202 4 +Difficulty walking 0.2739903631301946 0.6862086917799192 0.4925815175546197 1.0 0.7672542348247172 78 P42858,O14773,O43292,Q12768,P07602,P31483,Q15120,Q13510,Q9NR77,P35637,Q9NZJ7,O43681,Q15907,Q8TAF3,Q99720,O75477,Q8N201,Q15067 18 +Intrinsic hand muscle atrophy 0.5472982489768692 0.6855770402333395 0.4929798639705434 1.0 0.7672542348247172 4 Q9NR77 1 +Abnormal ureter morphology 0.3494404809365795 0.6843130979759232 0.4937774778574912 1.0 0.7672542348247172 27 Q7LGA3,P23786,O75844,Q8TAA9,O15360 5 +Abnormal dermatoglyphics 0.2700854241058566 0.6828215550521689 0.4947196074487865 1.0 0.7682894972116927 80 P61978,O95202,Q15907,Q6DKJ4,Q5SRE5,P98175,Q96J02,Q99567,P36776,Q9Y487,Q9Y4P3,Q6NUK1,Q9H2P0,Q9NXE4,Q9UL01,P62266,Q13535,O96028,O43909,Q9UIG0,P42345,P40855,P27635,Q9UBM7,Q9UHX1,P51812,O60568 27 +Papilloma 0.4623278666075937 0.6816992714406105 0.4954291282476069 1.0 0.7687921609346632 9 P21912,P18074,P16615 3 +Parkinsonism with favorable response to dopaminergic medication 0.4620530938878588 0.6802835392583981 0.4963249451794869 1.0 0.7694113097443764 9 P07602,P04062 2 +Abnormality of the ankles 0.3071581239256405 0.6736323112586212 0.5005451055581642 1.0 0.7746610794214627 40 P49902,O75844,Q96AY3,P07602,Q9NZJ7,Q9Y4P3,Q15043 7 +Prematurely aged appearance 0.2926165941704427 0.6704705959875291 0.5025578446536016 1.0 0.7769440466961496 46 O75844,P48651,Q9Y487,Q13535,Q13126,Q9Y4P3 6 +Abnormal sacrum morphology 0.3330823624812792 0.6702645632086729 0.5026891528989723 1.0 0.7769440466961496 30 P61978,Q8TAA9,P53701,Q03164,P27635,O43909,P01889,Q9UM00,O96028,O95202,Q6DKJ4,Q9Y4P3,Q9UIG0,Q14739 14 +Abnormal cardiac test 0.3672574809422103 0.6687589774761106 0.5036492389169116 1.0 0.777367431413944 22 Q9HD47,Q99959,Q99519,Q14BN4,P10253,P12235 6 +Abnormal skin morphology of the palm 0.2701775953787511 0.6687531494584262 0.5036529572230812 1.0 0.777367431413944 99 Q06136,P42345,P61978,Q99567,Q9Y487,Q9UL01,P16615,Q13535,O96028,O95202,Q9UHX1,Q15907,P98175,O60568,Q14739 15 +Abnormality of facial skeleton 0.2372896846628818 0.6685231888330803 0.503799684887513 1.0 0.777367431413944 353 Q7LGA3,Q8TD16,O14678,O95630,P78318,P51798,Q13315,P51571,Q13045,Q9Y4W2,Q9UM00,O95202,Q6DKJ4,Q15392,Q9H0U3,Q9UBN7,P98175,P21964,Q5SRE5,P04062,Q86XL3,O75844,Q2TAA5,O95831,Q15022,O43683,Q12768,P37268,P53701,Q99567,P16278,Q9Y619,Q9Y487,Q9UPT5,O15228,Q15427,Q9Y4P3,P07437,Q9NVI7,Q8N201,Q15043,Q6NUK1,P42858,O75648,P55795,P55011,Q06787,O15360,P61586,Q9NXE4,Q9UL01,Q96L58,Q13535,Q96PU5,O96028,Q03519,O75845,Q03518,Q16625,Q14739,Q00839,Q96RL7,P16435,P48651,O60762,O14936,Q9UBM7,Q9BT22,Q96PZ0,Q4J6C6,Q9UHX1,P51812,Q96MF7,Q9H490,O60568 75 +Abnormal glycosylation 0.3636341508388503 0.667574901893666 0.5044049829477533 1.0 0.7780430115455716 23 O60762,Q15904,Q9Y487,Q9BT22,P51571,P46977,Q9H0U3,Q8N511,Q2TAA5 9 +Bifid scrotum 0.493763994652352 0.6645810496189225 0.506318493324982 1.0 0.7804763503609378 7 P16435,Q9UBM7,Q9P2D1,Q96EK5,O60566 5 +Abnormality of temperature regulation 0.2692988314554379 0.6633718847157339 0.5070924078823367 1.0 0.781170424220898 112 P61978,P51798,O15460,Q13315,P06280,P00403,Q2TAA5,P23786,P07602,P49770,P10253,Q9NZ08,P03886,Q9NZJ7,O43772,Q8N1F7,Q14739,Q12769,O14936,Q8NFH4,P01889,Q13510,Q9NR77,P35610 24 +Supernumerary nipple 0.443695706263696 0.6626625989135508 0.507546668579236 1.0 0.7813326117359611 11 Q7LGA3,Q14738 2 +Skin dimple 0.3589127212691442 0.6596718438772847 0.5094644389888385 1.0 0.7829876888991544 24 P61978,Q8TAA9,P53701,Q03164,P27635,O43909,Q9UM00,O96028,O95202,Q6DKJ4,Q9Y4P3 11 +Generalized onset seizure 0.2688921579779234 0.6588431746806369 0.5099964793939316 1.0 0.7835461783281105 113 P61978,Q8WVX9,P04062,P07602,P11166,P16278,Q9Y619,P00367,Q96N66,Q14108,Q9NVI7,O43292,P55011,P03886,P00374,Q9NZJ7,Q99519,P42345,P05023,O60762,O14936,O75503,P51812,Q13510,Q9Y320,Q9NZ01 26 +Decreased specific anti polysaccharide antibody level 0.4887923602013593 0.6547497324795047 0.5126288996953576 1.0 0.7856779184958373 3 Q9H0U3 1 +Malabsorption 0.2926397826594552 0.6538612208477736 0.5132012198462046 1.0 0.7856779184958373 53 P42345,Q14566,P01889,P06280,Q9UJW0,Q9Y4P3,Q9NZ08,P09601,Q14739 9 +Abnormal renal physiology 0.2602032003473368 0.6526933671973347 0.513953979400342 1.0 0.786002771613107 170 P36551,Q96CU9,O15460,P06280,Q16134,O43676,P00403,P04062,O75306,P23786,Q10713,Q86Y39,Q13277,P49257,Q9NWS8,Q9Y4P3,Q9NZ08,Q6YHK3,P09601,Q14108,P21912,Q9Y6M9,Q9NPL8,Q02978,P03886,O15360,O95470,O43772,Q16625,Q8N1F7,Q9UBS4,Q9P032,Q8TAA9,Q92621,Q86YH6,P05023,O96000,P52429,Q07021,Q8NFH4,O76024,Q12769,Q9BT22,P01889 44 +Abnormality of the auditory canal 0.3682777084255701 0.6526779350424505 0.513963930297163 1.0 0.786002771613107 21 O96028,Q9Y619,Q15427,P16435 4 +Abnormality of the nasal tip 0.2690100832482139 0.6501411139003703 0.5156010740135395 1.0 0.7879876940351659 106 O75844,P23786,Q7LGA3,O43292,P61978,P42892,P16435,O95831,P16278,Q06787,Q9Y487,Q9UHX1,Q6DKJ4,Q96A33,P21964,Q8N201,P38159 17 +Hypercholesterolemia 0.4333085583709751 0.6495163224983523 0.5160046996450669 1.0 0.7880860731594282 12 Q13045,Q15904,Q8N511 3 +Simple ear 0.538086734833312 0.6480361344352119 0.5169615793903573 1.0 0.7890287443651772 4 P16435 1 +Abnormal phalangeal joint morphology of the hand 0.3190208406003536 0.6457343185146165 0.5184514311323216 1.0 0.7902642221262357 35 O75844,O76024,P16435,Q99567,Q9Y619,Q6DKJ4 6 +Crackles 0.4864312810038096 0.644327816300047 0.519362881610594 1.0 0.7904439345289703 3 Q86TI2,O95453 2 +Honeycomb lung 0.4864312810038096 0.644327816300047 0.519362881610594 1.0 0.7904439345289703 3 Q86TI2,O95453 2 +Aplasia of the uterus 0.4618147995143834 0.6442397126539867 0.5194200026080384 1.0 0.7904439345289703 8 Q9UNW1,O96028,O95202 3 +Hypoplasia of the radius 0.4544977983534446 0.6415849426435065 0.521142712156943 1.0 0.7920278183451609 9 P98175,Q15427 2 +Progressive leukoencephalopathy 0.4852640793697261 0.6391903799208415 0.5226990895906449 1.0 0.7934383304864959 3 Q9Y263,Q5JTZ9 2 +Abnormality of neuronal migration 0.2628220853938648 0.6384341355337553 0.5231911161365959 1.0 0.7935833906531584 155 P61978,P11177,Q16134,Q15392,Q86XL3,Q2TAA5,P23786,Q15022,Q10713,Q12768,P37268,Q9UPT5,Q9Y487,Q9NWS8,Q15427,P42695,P07437,Q96N66,Q6NUK1,P55011,Q06787,Q9NXE4,Q13535,Q96PU5,Q16625,P42345,O14936,Q6ZXV5,Q9UBM7,Q8NAT1,Q13885,P51812,Q9Y320,Q9NZ01 34 +Dystonia 0.2587929336399232 0.6366894577001089 0.5243271418622728 1.0 0.7947875696874778 172 P61916,Q9NP80,Q96CU9,Q13315,Q15907,Q99720,O14949,Q9P0J0,P04062,O75306,P07602,P16278,Q96N66,Q15067,Q15043,P04350,P17900,P42858,P03886,Q9NZJ7,Q96L58,Q6DKK2,O75569,O00584,Q9Y2Z2,Q96RL7,P35637,O15118 28 +Telangiectasia of the skin 0.3624218357006222 0.6329775538967315 0.5267483010147986 1.0 0.7977327869217081 22 P06280,Q14739,Q8IZA0 3 +Dental crowding 0.3235167943900501 0.630955873541377 0.5280693770809639 1.0 0.799416854323284 32 O75844,Q9Y5W7,P27635,Q9ULH0,Q9UBM7,Q9UL01,Q13535,P51812,Q96A33 9 +Fatigable weakness of respiratory muscles 0.421568630540125 0.630018780808701 0.5286822966603264 1.0 0.7998234940683414 13 Q15165,Q92804 2 +Eyelid myoclonus 0.4434432550309858 0.6212492855095623 0.5344356160977279 1.0 0.8069508847546455 10 P00374 1 +Trichorrhexis nodosa 0.4808338325504981 0.6197817387779978 0.535401492846971 1.0 0.8075475740673229 3 Q6PGP7 1 +Emotional lability 0.2898963013898206 0.6186474537685305 0.5361486331877323 1.0 0.808224058984492 58 O75306,P07602,Q96RL7,Q15165,Q96CU9,Q7KZN9,Q9NZJ7,P35637,P49770,O43681,Q9P0J0,Q92804 12 +Corpus callosum atrophy 0.4036326388364041 0.616185500915571 0.5377720966641899 1.0 0.8101226107539763 15 Q9H9P8,P51970,P51572,O75503,Q8WVX9,O60313 6 +Aplasia hypoplasia involving the femoral head and neck 0.4348621793680076 0.6150614128324774 0.5385141639253019 1.0 0.8107377853522205 11 Q96L58,Q96HY6 2 +Abnormality of the forearm 0.2894275966862481 0.6134015039314689 0.5396108918748377 1.0 0.8110747989810727 57 Q32P28,Q96AY3,P16435,P48651,Q96L58,Q13535,O96028,O95202,Q15427,Q9Y4P3,P98175 11 +Abnormality of dental structure 0.2689022777543382 0.612050584151675 0.5405042905760382 1.0 0.8111357883779449 78 O75844,P55011,Q96AY3,P53701,P48651,P16278,P51798,Q9Y366,P51648,Q9Y487,P61586,Q13045,Q96L58,Q13535,Q6P4Q7,P21964,Q9Y4P3 17 +Synostosis involving bones of the hand 0.4263448026587709 0.6109367558982973 0.5412414503057028 1.0 0.8119495570294786 12 P48651,Q96L58,P16435 3 +Decreased facial expression 0.3359939087967444 0.610454477607912 0.541560789992938 1.0 0.8121663751798548 28 Q06787,P04062,Q15043 3 +Aganglionic megacolon 0.3650866002415809 0.6091672443760111 0.5424135894130608 1.0 0.8124825150530632 20 Q10713,P42892,O15360,Q9UBM7,Q15427,P21964 6 +Abnormality of the palm 0.26338083607427 0.6089030248599189 0.5425887191417202 1.0 0.8124825150530632 125 Q06136,P61978,P16615,O95202,Q15907,Q6DKJ4,P98175,Q99567,Q9Y619,Q9Y487,Q9UL01,Q13535,O96028,Q14739,P42345,P16435,P48651,Q9UHX1,O60568 19 +Aplasia hypoplasia of the nipples 0.3849862741127344 0.604371336294445 0.545596788289997 1.0 0.8159625236749087 17 Q12768,P07437,O96028,O95202,Q96A33 5 +Hernia 0.2619238479885146 0.6024205645949128 0.5468942245993591 1.0 0.8167666802629484 143 P51970,O14678,O95202,P21964,P08236,Q32P28,Q10713,P53701,P16278,Q9Y487,Q9NWM8,Q9Y4P3,P07437,Q9UL01,Q99519,Q96PU5,O96028,Q14739,P42345,P48651,Q6ZXV5,Q9UHX1 22 +Gray matter heterotopia 0.3165906120811245 0.6023912698749001 0.5469137198230807 1.0 0.8167666802629484 34 Q6NUK1,P61978,Q2TAA5,P11177,Q6ZXV5,Q06787,Q96PU5,P42695,Q86XL3 9 +Neonatal hypoglycemia 0.4530930067012385 0.6013149064783332 0.5476302629664791 1.0 0.8168717150237402 8 O43772,P42345 2 +Aplasia hypoplasia of the optic nerve 0.3512493724128123 0.6008605827979073 0.5479328488954893 1.0 0.8168717150237402 24 Q96KP1,P61978,Q00839,P37268,O14936,Q9UHX1,Q9NVI7,P30153 8 +Attenuation of retinal blood vessels 0.4798723692321227 0.600684712990648 0.5480500028299409 1.0 0.8168717150237402 7 P38435 1 +Abnormal umbilicus morphology 0.2857756055358027 0.6005144176408931 0.548163455189445 1.0 0.8168717150237402 66 O75844,Q6NUK1,P42345,Q15022,O15360,Q9Y487,Q99519,Q9NWM8,Q6DKJ4,Q9Y4P3,P07437,P21964,P08236,Q14739 14 +Abnormality of digestive system morphology 0.2507641918945643 0.6004373382163548 0.5482148100396087 1.0 0.8168717150237402 258 P61978,O14965,P16615,P06280,O95202,Q6DKJ4,Q15392,Q01844,P98175,P21964,P00403,P04062,O75844,P08183,Q15022,O43683,Q10713,P53701,Q99567,Q13277,Q9UJW0,Q15427,Q9Y4P3,Q9NZ08,P09601,P42892,P03886,O15360,Q9UL01,Q96PU5,O96028,Q14566,Q14739,P42345,Q8TAA9,O76024,P16435,P48651,Q6ZXV5,Q6PGP7,Q5HYI8,Q9BT22,P01889,Q96A33,Q14738 45 +Abnormality of the bladder 0.2629650858359711 0.5969162780923329 0.5505632786755876 1.0 0.8193199848580334 124 P61978,O95630,Q8WVX9,Q99720,P21964,P04062,Q86XL3,Q12768,P07602,P11166,Q9NWM8,O43681,Q9UJS0,Q9Y4P3,P42695,Q06787,Q9NZJ7,Q9UL01,P22626,P12235,Q8TAA9,Q00839,O76024,P16435,P35637,P01889,Q9UHX1,P51812,Q9NR77 29 +Urinary incontinence 0.2854733535279289 0.5945418089493616 0.5521497874186094 1.0 0.8205814514530705 45 Q8TAA9,Q12768,P07602,P11166,Q04446,Q99496,Q9H2P0,Q06787,P35637,Q9NZJ7,Q8WVX9,O43681,P51812,Q99720,P54886 15 +Streak ovary 0.4783993897030379 0.5939960551413958 0.5525147514594293 1.0 0.8205814514530705 7 P82650,O14974,P49590,Q8IY37,P51809 5 +Rib fusion 0.4449828963506248 0.5935338708042237 0.5528239223091069 1.0 0.8205814514530705 9 O96028,O95202,Q6DKJ4 3 +Type 1 muscle fiber atrophy 0.4769490941424332 0.5874277595779778 0.5569164547165857 1.0 0.8245487089271055 7 P61978 1 +Abnormal platelet volume 0.4432066115804843 0.5846557750142243 0.5587791964885991 1.0 0.8255895673856891 9 O75845,Q14739 2 +Postural instability 0.3902361582622121 0.5841648311073253 0.5591094203585614 1.0 0.8255895673856891 16 O75503,P04062 2 +Pigmentary retinopathy 0.2862461921537006 0.5831408914213728 0.5597984581992974 1.0 0.8255895673856891 50 O75306,Q9UG56,O76024,P53701,P03886,Q96CU9,P00403,Q9P0J0,Q15067 9 +Hepatocellular adenoma 0.4241540256709495 0.5830569508500432 0.559854962431158 1.0 0.8255895673856891 2 P10644 1 +Abnormal urine carbohydrate level 0.4056062813957065 0.5815164136587959 0.5608924592147 1.0 0.8255895673856891 14 Q6PGP7,P10253,P16278,Q99519 4 +Abnormality of the lens 0.251309505122678 0.5811863815604025 0.5611148450428922 1.0 0.8255895673856891 219 Q7LGA3,Q06136,P06280,P21964,P00403,P23786,Q99797,Q10713,P53701,O15228,Q9Y4P3,Q9NZ08,Q9NVI7,Q9Y287,Q8N201,P03886,O15360,P61586,Q99519,Q96L58,P08670,O75845,Q03519,P22626,Q15800,P12235,Q03518,Q16625,Q6ZXV5,O14979,P01889,Q13126,Q8NAT1,P04439,O60313,O60568 36 +Abnormality of the hallux 0.2866414461181366 0.5810362001087834 0.5612160560706698 1.0 0.8255895673856891 56 Q7LGA3,P42858,O75648,P61586,Q96L58,O96028,O95202,Q15427,Q6DKJ4,Q9UHX1,Q9Y4P3,P04062 12 +Abnormality of the amniotic fluid 0.2643444490179501 0.5804864136416655 0.5615866462271506 1.0 0.8255895673856891 96 O75844,P23786,Q7LGA3,O43683,P16435,Q6PGP7,Q99567,O15360,P51798,Q9BT22,Q70HW3,Q96L58,P51114,Q9NVI7,Q9UHX1,P21964,Q14739,P04062 18 +Hypoplastic helices 0.4235705950991887 0.5803085716052611 0.5617065481072074 1.0 0.8255895673856891 2 Q9UDR5 1 +Hamartoma of tongue 0.4235705950991838 0.5803085716052363 0.5617065481072241 1.0 0.8255895673856891 2 Q8NCM8 1 +Increased head circumference 0.2604225571786867 0.5788567599329991 0.5626858285309515 1.0 0.8267673495745732 134 Q7LGA3,Q8TD16,Q99575,P78318,P51798,Q8WVX9,Q9UM00,Q9UBN7,Q16134,Q6DKJ4,Q15392,P08236,O75844,Q9H9P8,Q15022,Q96J02,Q12768,P07602,Q10713,P11166,Q5T2R2,P49770,P21912,P42858,O75648,P55011,Q06787,Q9NZJ7,Q99519,Q14739,P42345,P48651,P40855,Q96PZ0,Q8NAT1,P51812,O43505,Q14738 38 +Macular purpura 0.3805461765515924 0.5759378177112988 0.5646572126488085 1.0 0.8279913568550105 17 P38435,Q16625,P04062,Q99519 4 +Perseveration 0.4998604411026425 0.5755643603734726 0.5649096764206498 1.0 0.8279913568550105 6 P35637 1 +Adrenal insufficiency 0.3403147874303192 0.5754437623501718 0.5649912144132294 1.0 0.8279913568550105 26 Q13423,O95470 2 +Slow decrease in visual acuity 0.4742496677803361 0.5752491392348916 0.5651228137294959 1.0 0.8279913568550105 7 P03886 1 +Abnormality of the nail 0.261915645271476 0.5744410966859649 0.5656693495719989 1.0 0.8282890568261261 123 Q06136,O95630,P10321,P16615,O95202,Q6DKJ4,O75844,P23786,Q15022,Q12768,P53701,Q9Y619,Q9Y487,Q9Y4P3,Q6NUK1,P42892,Q96L58,Q13535,O96028,Q14739,O60762,O14936,P48651,Q9Y366,O60568,Q14738 26 +Zonular cataract 0.4409888305388461 0.5736143326049435 0.5662288107302891 1.0 0.8284978572495411 9 P11166,Q99797,P08670,O76024 4 +Abnormal iliac wing morphology 0.3964905713793692 0.5732805658000707 0.5664547418597354 1.0 0.8284978572495411 15 Q8TAA9,P16278,Q96L58,P51812,O95831 5 +Frequent falls 0.2972854418046315 0.5712060156757611 0.5678600009019457 1.0 0.828860220671321 40 P07602,P12235,Q13510,Q9NR77,P04062 5 +Delayed ossification of carpal bones 0.469585526141017 0.5711960603693862 0.5678667484490538 1.0 0.828860220671321 3 P36776 1 +Heterotaxy 0.5185175475668423 0.5699877924854919 0.5686859778514015 1.0 0.828860220671321 4 O96028 1 +Hyperhomocystinemia 0.5086734502991612 0.5694891027804482 0.5690242638744765 1.0 0.828860220671321 5 O14678 1 +Azoospermia 0.3958239904360228 0.569307797720971 0.5691472759312215 1.0 0.828860220671321 15 P04062 1 +Genital neoplasm 0.2936824900615801 0.5690393291104365 0.5693294501313795 1.0 0.828860220671321 41 O75874,O14965,P48735,Q5HYI8,Q13423,Q01844 6 +Central sleep apnea 0.4979761615452035 0.5676438301660891 0.5702768391632675 1.0 0.8292664146330331 6 Q93009,Q96A33,Q969N2,P53007 4 +Abnormal cerebellar vermis morphology 0.2625737006376525 0.5662394562946259 0.5712310112289445 1.0 0.8296089260311011 90 Q8WVX9,Q9UM00,Q15907,P98175,P23786,Q96KP1,O43683,Q12768,Q10713,Q99567,Q9Y487,P07437,Q8N201,Q6NUK1,P42858,Q13535,Q8NFH4,Q9UBM7,Q8NAT1,Q03154,Q9H490 21 +Abnormality of the coagulation cascade 0.3000254501000596 0.5660171020459124 0.5713821547501126 1.0 0.8296089260311011 39 Q4KMQ2,O75648,Q6NUQ1,O60762,P38435,Q9Y619,Q9Y487,P49257,P51571,Q5XKP0,Q16836 11 +Equinovarus deformity 0.5075362029570121 0.5648814950342697 0.572154371098792 1.0 0.8299990272461223 5 Q9NR77 1 +Atelectasis 0.4097617474804114 0.5632584047503469 0.573258937690261 1.0 0.8302247582633893 13 Q13510,P21964 2 +Dysphonia 0.3080425067677509 0.5622542253672942 0.5739428209541635 1.0 0.8306973040975213 36 Q96RL7,Q99519,Q6DKK2,O75569,Q9Y4P3,Q13510 6 +Nephrotic syndrome 0.3206842435397034 0.5611113544226428 0.5747216282020804 1.0 0.8315654576851029 30 Q92621,Q12769,P52429,Q86YH6,Q9BT22,P06280,O95470,Q14108,Q8N1F7 9 +Aplasia hypoplasia involving the skeletal musculature 0.4245124150486561 0.5602536950169738 0.575306406757115 1.0 0.8319472216418493 11 Q9NR77,Q8NAT1 2 +Blue sclerae 0.3489023059727912 0.5574102726551668 0.577247148431216 1.0 0.8320292515390026 23 Q96L58,O75718,Q96AY3,Q9UL01 4 +Abnormality of the 5th toe 0.4377052673930118 0.5573579824661077 0.5772828672925601 1.0 0.8320292515390026 9 Q10713,Q9UBM7,O75845,O43909,Q14739 5 +Postaxial foot polydactyly 0.4377052673930118 0.5573579824661077 0.5772828672925601 1.0 0.8320292515390026 9 Q10713,Q9UBM7,O75845,O43909,Q14739 5 +Elevated circulating alanine aminotransferase concentration 0.4165009865789673 0.5572509742028486 0.577355966722213 1.0 0.8320292515390026 12 P10253,Q15904,Q96MF7,Q96RL7 4 +Abnormal circulating gonadotropin concentration 0.4013836232247976 0.5571415945768246 0.577430690581024 1.0 0.8320292515390026 14 P16435,Q8IY17,Q99496,Q06787,Q8IY37,Q969G3,Q96MF7,P82650,P51659,P51809 10 +Weakness of muscles of respiration 0.3179009061135806 0.557134100005722 0.5774358107439619 1.0 0.8320292515390026 31 Q8TD16,O95831,P43243,P50402,P22626,P10253,Q13510,P12235,Q15067 9 +Wide mouth 0.2773050784492777 0.5569678987768626 0.5775493620777623 1.0 0.8320292515390026 70 Q7LGA3,P42345,P55795,P55011,P48651,Q6PGP7,P16278,Q9UBM7,P15586,P51571,Q9UM00,Q9UBN7,Q6DKJ4,Q15427,P51812,Q9H490,Q9Y4P3 17 +Hypoplasia of the musculature 0.4953272123352459 0.5565564372910311 0.5778305243567035 1.0 0.8321762604343597 6 Q9NR77 1 +Abnormality of circulating adrenocorticotropin level 0.4369353104482567 0.5535622496856908 0.579878467400134 1.0 0.8338332898610408 9 Q13423 1 +Intellectual disability progressive 0.4157569104891279 0.55323706113169 0.5801010922874057 1.0 0.8338488571305687 12 O95831,Q15067,P53701 3 +Chronic diarrhea 0.3539640103408146 0.5501997514508296 0.5821823740381658 1.0 0.8361110694841787 21 Q15904,Q13277,Q96A33,Q13510,Q14738 5 +Craniofacial hyperostosis 0.4934938686870106 0.5489160267341152 0.5830630790432569 1.0 0.8371171400602508 6 P48651,Q96L58,P51812 3 +Abnormal protein glycosylation 0.3675530406028946 0.5476303188724184 0.583945766846141 1.0 0.8373767694981241 18 Q15904,Q9Y487,Q9BT22,P51571,Q9H0U3,Q8N511,Q2TAA5 7 +Abnormality of the endometrium 0.4679720124879492 0.547173080275965 0.5842598286136744 1.0 0.8375412415116111 7 P52701,P21912,Q07864 3 +Abnormality of prothrombin 0.3919417871557925 0.546284414454502 0.584870447935419 1.0 0.838157958392337 15 Q9H845,Q6NUQ1,P38435,P49257,Q9UJS0,Q5XKP0,A2RRP1,Q16836 8 +Lethargy 0.2592405922195298 0.5444411153032129 0.586137959091797 1.0 0.8387394159455962 82 O14678,Q96CU9,O43676,P61313,O75306,P23786,P11166,Q86Y39,Q9Y619,P49770,Q9UJS0,Q9NWS8,Q96EY8,Q9Y6M9,Q9NPL8,P03886,P12235,O43772,P23378,Q9P032,O96000,Q16836 22 +Decreased methylcobalamin 0.5119052355139908 0.5442101921789307 0.5862968389482732 1.0 0.8387394159455962 4 O14678 1 +Ventricular septal hypertrophy 0.4628545263004247 0.5426397065820956 0.5873778946940258 1.0 0.8389049181519963 3 P06280 1 +Aplasia hypoplasia of the earlobes 0.4054474760117496 0.5392654195833747 0.5897037259774338 1.0 0.8391078640608041 13 P98175,P21964 2 +Abnormal male reproductive system physiology 0.2837115606346294 0.5390813889499778 0.5898306967466131 1.0 0.8391078640608041 43 P16435,O15360,Q06787,Q13315,Q13423,Q9Y4P3,P04062 7 +Limb girdle muscle weakness 0.3316157616360533 0.5387583497656083 0.5900536060463704 1.0 0.8391078640608041 27 P07602,Q9NZJ7,O14979,Q13126,P12235 5 +Vestibular dysfunction 0.3228205971618004 0.5385793942241728 0.5901771088642569 1.0 0.8391078640608041 29 P46976,Q02978,O15460,P01889,P06280,Q9NZ08,P21912,Q15043 8 +Bulbous nose 0.2824943784735041 0.5376329586361812 0.5908304715618109 1.0 0.8391078640608041 51 P23786,P42892,P16435,Q06787,Q96A33,P21964,Q8N201,P38159 8 +Increased intracranial pressure 0.3744958654674585 0.5376282769277959 0.5908337043610186 1.0 0.8391078640608041 17 Q9NZJ7,Q9NZ08,P07602 3 +Long philtrum 0.2583189702709033 0.5366731838641319 0.591493382436318 1.0 0.8391078640608041 141 Q7LGA3,Q92974,Q8WVX9,Q6DKJ4,P21964,Q2TAA5,Q15022,Q96KP1,P11166,P16278,Q9UPT5,Q9Y487,Q9Y4P3,P07437,Q8N201,Q6NUK1,P42858,O75648,P55011,Q9UL01,Q96L58,O75845,O75718,Q16625,P42345,P16435,Q6PGP7,O14936,Q9UBM7,Q96PZ0,Q9UHX1,P51812,O60568,Q14738 34 +Scarring 0.3110938337787805 0.5341311160654502 0.5932508230747575 1.0 0.8413345216903012 33 Q9NWM8,P04439,P61586,Q9UL01 4 +Pelvic kidney 0.4329217224972694 0.5338791534668994 0.5934251458413942 1.0 0.8413345216903012 9 Q9UHX1 1 +Short long bone 0.2967066497887922 0.5327577854294608 0.5942012595148336 1.0 0.8414078182584324 39 P16278,Q96L58,Q13535,O15228,Q15427,Q9UHX1,Q96HY6,P98175 8 +Absent forearm bone 0.4645386209163973 0.5319703160906546 0.5947465547275186 1.0 0.8414626991138401 7 Q15427 1 +Abnormal c peptide level 0.5084386023222506 0.5308282928801212 0.5955377720803987 1.0 0.8417610249727814 4 Q16836 1 +Lambdoidal craniosynostosis 0.5081901134946392 0.5298726966247965 0.5962001977092006 1.0 0.8422251234100899 4 P16435 1 +Vertebral fusion 0.4112955274413962 0.52930976135801 0.5965905852130353 1.0 0.8422251234100899 12 O96028,O95202,Q9UHX1 3 +Excessive salivation 0.3169713461950457 0.5289914307897566 0.5968113943806008 1.0 0.8422251234100899 30 Q96RL7,Q9NR77,P55795,P15586 4 +Unilateral renal agenesis 0.3444861417859787 0.5250589068340203 0.5995422415113056 1.0 0.8448508504887856 23 Q7LGA3,P16435,Q9UHX1,Q15427,Q86XL3 5 +Abnormal circulating carboxylic acid concentration 0.2606917049059954 0.5239951511396134 0.6002819124013792 1.0 0.8452222426756593 96 O14678,Q9NP80,P36551,P48735,Q16134,Q99707,Q9UGP8,Q9P0J0,P23786,Q9H9P8,Q99797,P37268,P11166,Q9Y619,P28288,Q9UJS0,Q96EY8,O75648,P03886,P05067,O75845,P23378,P09001,Q14739,Q9Y2Z2,O96000,Q6PGP7,O14936,P40855,P14854,Q5XKP0 31 +Abnormal hdl cholesterol concentration 0.506482896660729 0.5233206948539384 0.600751101877453 1.0 0.8452222426756593 4 Q9UJS0 1 +Abnormality of coagulation 0.282049659764433 0.5232986587989253 0.6007664341835901 1.0 0.8452222426756593 59 O75874,Q4KMQ2,O75648,Q6NUQ1,O60762,P38435,P48735,Q9Y619,Q9Y487,P49257,P51571,P28288,Q5XKP0,Q16836 14 +Neoplasm of the male external genitalia 0.4306779334573901 0.5229529978051014 0.6010069622626883 1.0 0.8452222426756593 9 Q13423 1 +Sensory axonal neuropathy 0.3877420124385203 0.5216075703254135 0.6019435913150637 1.0 0.8460225478318961 15 Q8IV08,Q15067,P22626 3 +Preaxial foot polydactyly 0.505259209614654 0.5186388540860305 0.6040126089420186 1.0 0.8483200063919645 4 O96028 1 +Obsessive compulsive behavior 0.2790952752833042 0.5180406723284217 0.6044298921852782 1.0 0.8486495252622552 46 P55795,Q96RL7,Q06787,O75503,Q6DKK2,Q5JRX3,Q9Y4P3 7 +Enterocolitis 0.409859976662783 0.5168043445542956 0.6052927469337166 1.0 0.8491518916394124 2 P49748 1 +Aspiration pneumonia 0.3327660989823428 0.5162582139204749 0.6056740767118829 1.0 0.8491518916394124 26 P16278,P04062 2 +Small earlobe 0.4353091696454508 0.5160092361370471 0.6058479584328837 1.0 0.8491518916394124 8 P98175 1 +Decreased muscle mass 0.3539952876041229 0.5159571840004871 0.6058843135567482 1.0 0.8491518916394124 19 O96028,O95202,Q9Y487,Q9UL01 4 +Chronic constipation 0.3244116154319375 0.5147658960659988 0.6067166195422025 1.0 0.8496539679997748 28 Q7LGA3,P04062 2 +Peptic ulcer 0.4156246037221136 0.5141366134870576 0.6071564806422516 1.0 0.8499093127640557 11 P04062,Q9Y4P3 2 +Brushfield spots 0.4557604806700793 0.513002170026949 0.6079498027388468 1.0 0.8505073121122199 3 P40855 1 +Abnormal urine cytology 0.2775242443092612 0.5124066858462296 0.6083664127441009 1.0 0.8507930027289599 44 Q02978,O15460,Q14108,P49257,P01889,P06280,P09601,P21912,Q6YHK3,P04062,Q8N1F7 11 +Dilated third ventricle 0.4555004377006302 0.5119251608709909 0.6087033880910595 1.0 0.8507930027289599 3 Q93009,Q9ULH0 2 +Hip dislocation 0.2798866866778459 0.5109282681269637 0.6094012862305087 1.0 0.8512863563946296 65 O75844,Q9Y487,Q96L58,Q13535,O96028,O95202,Q15427,Q9UHX1,Q96A33,Q14738 10 +Abnormality of lower limb epiphysis morphology 0.3532388937171501 0.510897517013356 0.6094228199243517 1.0 0.8512863563946296 19 Q7LGA3,Q96L58,O60568,O95831 4 +Pleural effusion 0.400168462873172 0.5102317660344017 0.6098890998731583 1.0 0.8516816224859314 13 Q9NZ08,Q14739 2 +Emg myopathic abnormalities 0.314706524213435 0.5095477782532285 0.6103683175319756 1.0 0.8518573862175016 30 P31483,P13473,P51114,P22626,P12235 5 +Abnormality of the glabella 0.4338535439021749 0.5091749685803133 0.610629586960439 1.0 0.8518573862175016 8 O96028,O95202 2 +Late onset 0.4211179545072245 0.5076116786916249 0.611725698759471 1.0 0.8529644647168374 10 P43304,O76024,P31483 3 +Hyperpituitarism 0.3526905069342682 0.5072355983256895 0.6119895200985828 1.0 0.8530763007434791 19 P16435,Q99496,Q9BUK6,Q06787,Q8IY37,P35222,Q969G3,P10644,Q96MF7,P82650,P51659,P51809 12 +Hip dysplasia 0.2801325356785585 0.5061256151520966 0.612768469527522 1.0 0.8533629605521156 55 Q7LGA3,P42858,P61978,O75648,Q96L58,Q13535,O96028,O95202,Q15907,Q9UHX1,Q96A33,Q9NVI7 12 +Retinal dystrophy 0.2803295125665089 0.5060938222280076 0.6127907872005207 1.0 0.8533629605521156 56 Q10713,P53701,P03886,P38435,Q8NAT1,Q9Y287 6 +Muscular hypotonia of the trunk 0.2571228292745711 0.5047447152509865 0.6137381502865922 1.0 0.8539764738638836 84 O75306,P04350,P17900,P42858,Q2TAA5,P07602,Q6ZXV5,Q9NZJ7,Q96PU5,Q9NVI7,Q16625,Q96N66,O60313,Q15043 14 +Redundant neck skin 0.4580845283968175 0.5037026292710785 0.614470360457146 1.0 0.8543340218281283 7 Q9Y487 1 +Delayed ability to roll over 0.5006919014962148 0.5012734512391875 0.6161786870486545 1.0 0.8554995397291763 4 P51970 1 +Absent toe 0.3344813502134016 0.5009606830516431 0.616398793607634 1.0 0.8554995397291763 25 Q7LGA3,P42858,O75648,Q96PZ0,O96028,O95202,Q15427,Q9UHX1 8 +Aortic aneurysm 0.2800454911260914 0.4997955643318778 0.6172190342289201 1.0 0.8559998904559889 58 Q7LGA3,O75844,Q6NUK1,P61978,O75648,P42858,Q6ZXV5,Q06787,O15460,Q96L58,Q96PZ0,P01889,Q96PU5,Q9Y4P3,Q96MF7 15 +Abnormality of pain sensation 0.3223349494405846 0.4978973552698617 0.6185563915015777 1.0 0.8568315429088641 28 O15269,P61978,O15270,Q06787,Q9UL01,Q9NR77,O95831 7 +Retinal atrophy 0.3084951120219733 0.4957991808986225 0.6200361028413459 1.0 0.8578581696846019 32 Q7LGA3,P42858,O75648,Q10713,P51648,Q96PZ0,P04439,P04062 8 +Decreased activity of mitochondrial complex iii 0.455671647422868 0.4932435411041717 0.6218405158837221 1.0 0.8598425704749325 7 Q9Y584 1 +Arachnodactyly 0.3079699113579452 0.4911669455282323 0.6233083755359672 1.0 0.8610374783095209 32 P55795,P16435,Q9UL01,Q96L58,O96028,P21964 6 +Abnormality of the thyroid gland 0.2588343652508364 0.4907103566831915 0.6236313203856088 1.0 0.8610374783095209 111 O75874,P42892,P03886,P48735,Q06787,Q13423,O95470,Q9Y4P3,P12235,P21964,O60313,P00403 12 +Kyphoscoliosis 0.2792691179988099 0.4898946131025985 0.624208475136149 1.0 0.8615752078627861 60 O75844,Q96AY3,Q8TB36,Q9Y487,Q9UL01,Q96L58,Q9NWM8,Q9NR77 8 +Abnormal location of ears 0.24625153718158 0.4882480152749228 0.6253741782344489 1.0 0.8620171498540016 257 Q7LGA3,O95630,P78318,Q9UM00,Q9UBN7,O95202,Q6DKJ4,Q15392,Q5SRE5,P98175,P61313,P21964,P04062,O95831,O75844,P23786,Q15022,O43683,Q12768,Q96KP1,Q96J02,P37268,Q10713,Q99567,P16278,Q9Y619,Q9Y487,Q9UPT5,P78527,Q15427,Q9Y4P3,P07437,Q8N201,Q15067,Q6NUK1,P55011,P42892,Q9NXE4,Q9UL01,P15586,Q99519,Q96L58,Q13535,O96028,Q16625,Q14739,P16435,Q6PGP7,Q9Y366,Q9UBM7,Q96PZ0,Q8NAT1,Q4J6C6,Q9UHX1,Q9H490,O60568,Q14738 57 +Episodic pain 0.3888247043247547 0.486035908301936 0.6269417069131391 1.0 0.8636262159829656 14 P23786 1 +Abnormality of the lower urinary tract 0.2473498601892081 0.485610124369842 0.6272436168214219 1.0 0.8636262159829656 227 P51970,P61978,Q9UBX3,P51571,O95202,Q99720,P21964,P04062,Q86XL3,O75844,P07602,P37268,P53701,Q9Y619,Q9NWM8,Q9Y4P3,P42695,P07437,Q06787,O15360,Q9NZJ7,Q9UL01,Q13535,O96028,P22626,P12235,P42345,Q8TAA9,O76024,P16435,P48651,P35637,P01889,Q9UHX1,Q9NR77 35 +Apneic episodes precipitated by illness fatigue stress 0.402567094515754 0.4839454888015663 0.6284245559808201 1.0 0.8638048778363581 2 P53007 1 +Abnormality of the pituitary gland 0.2776789952288276 0.4833526740824871 0.6288453453183687 1.0 0.8641276173762618 65 O75874,P48735,Q07864,Q9UM00,Q969G3,P82650,Q12768,Q03164,P52701,Q9BUK6,Q14697,P35222,Q9P2D1,P10644,P51659,Q15233,Q8NI27,Q9H2P0,O14654,Q06787,Q96GW9,Q9UBS4,O76024,P16435,Q8IY17,Q99496,Q4J6C6,Q9UHX1,Q96MF7,Q8IY37,P51809 31 +Lewy bodies 0.4529533026909267 0.4815343202195474 0.6301367936142324 1.0 0.8648139493871487 7 P04062 1 +Aplasia hypoplasia of the nails 0.2728336435214433 0.4814104820927768 0.630224788270979 1.0 0.8648139493871487 69 O75844,P23786,Q6NUK1,Q15022,Q12768,P48651,O14936,O95630,Q9Y487,P16615,Q96L58,Q14738,Q9Y4P3,Q14739 14 +Homocystinuria 0.4864463249818599 0.4813390988990039 0.6302755128335957 1.0 0.8648139493871487 5 O14678 1 +Overgrowth 0.4767416147104502 0.4804573670361414 0.6309022110220674 1.0 0.8654182676139727 6 P61978 1 +Abnormality of the humeroradial joint 0.3877461421742599 0.4800350743376161 0.6312024531065146 1.0 0.8655745564146595 14 Q96L58,Q13535,P16435 3 +B cell lymphoma 0.4858833734384453 0.4791624683845004 0.6318230521527188 1.0 0.8661699322223463 5 Q13315,Q9H0U3 2 +Exertional dyspnea 0.3564897720515048 0.4763355589736787 0.6338353360901454 1.0 0.8681600741376225 18 O75844 1 +Congenital hip dislocation 0.3310279669901916 0.4750170782039241 0.6347748005900897 1.0 0.8684227690051699 25 Q9UHX1,Q9Y487 2 +Atypical absence seizure 0.44557922381093 0.4713611483777312 0.6373828555200218 1.0 0.8704528943991833 3 Q96CW1,Q05086 2 +Limited hip movement 0.3857191777992723 0.4688062399411875 0.6392081393199653 1.0 0.871213322040287 14 Q7LGA3,O75844 2 +Squamous cell carcinoma of the skin 0.4918272037361409 0.4680831533784931 0.6397251261268215 1.0 0.871213322040287 4 P02545,P18074,P19447 3 +Bladder diverticulum 0.4249779756439584 0.4680449251200124 0.6397524631424552 1.0 0.871213322040287 8 Q9NWM8 1 +Cranial asymmetry 0.4736115010701678 0.4679576669279989 0.6398148632805551 1.0 0.871213322040287 6 O96028,O95202 2 +Abnormality of prenatal development or birth 0.2452850181228655 0.4673966185939881 0.6402161413956939 1.0 0.871249031319389 258 Q7LGA3,P61978,P61916,P51798,Q7KZN9,Q96CU9,Q70HW3,Q13045,O43676,O95202,P21964,P08236,P04062,O75844,P23786,O75306,O43683,Q12768,Q86Y39,Q99567,P16278,Q9Y619,Q9Y487,Q15427,Q9Y4P3,Q9NVI7,Q16637,Q9Y6M9,Q9NPL8,P03886,O15360,Q99519,Q96L58,P51114,O96028,O43772,O75718,Q14739,P10619,Q8TAA9,P16435,Q6PGP7,Q9BT22,O15118,Q4J6C6,Q9UHX1,Q13510,O60313 48 +Leg muscle stiffness 0.3984830805134202 0.4658503523195697 0.6413226205052633 1.0 0.8722438216825098 2 Q6PI48 1 +Abnormal blood transition element cation concentration 0.40597462546483 0.465193694740348 0.6417927536542529 1.0 0.8723286316451111 11 Q6PGP7,Q15904,Q9Y487 3 +Sound sensitivity 0.4184381886784096 0.4644088802643802 0.6423548289742764 1.0 0.8723708083643638 9 P17900,Q9Y4P3 2 +Underdeveloped supraorbital ridges 0.3845390980924779 0.4622987474307578 0.6438670977490997 1.0 0.8730821033245546 14 Q6NUK1,P16435,Q6PGP7,Q99519,P98175 5 +Enamel hypoplasia 0.3623123463263041 0.4622162500512559 0.6439262511555492 1.0 0.8730821033245546 17 P51648,P61586 2 +Posterior fossa cyst 0.4814444239720029 0.4621048868370785 0.644006105917617 1.0 0.8730821033245546 5 Q12768,Q9UHX1 2 +Triangular mouth 0.4474284584312832 0.4579867428188278 0.6469619657834209 1.0 0.8758371363997541 7 Q10713 1 +Delayed ability to stand 0.4890850268747078 0.4579604512024232 0.6469808549556513 1.0 0.8758371363997541 4 P10253,P21912 2 +Abnormal circulating bilirubin concentration 0.3130181125134024 0.4571785490273592 0.6475427153106632 1.0 0.8760706970391972 29 P23786,O75648,P11166,P36551,O14936,P28288,Q9UJS0,O75845,Q9UGP8,Q14739 10 +Abnormality of the supraorbital ridges 0.3286079072064311 0.4569932962382475 0.6476758639636748 1.0 0.8760706970391972 25 Q6NUK1,Q15022,P16435,Q6PGP7,Q99519,Q9Y4W2,P51812,P98175,P38159 9 +Abnormal circulating copper concentration 0.47985233598011 0.4560334825048561 0.6483659012384537 1.0 0.8760706970391972 5 Q9Y487 1 +Abnormal vitreous humor morphology 0.4469576940740776 0.4559962835223198 0.6483926507247766 1.0 0.8760706970391972 7 P53701 1 +Decreased cd4 cd8 ratio 0.4868336121501666 0.4497024436297994 0.6529250091263761 1.0 0.8766747221568439 4 Q9H0U3,P17812 2 +Clubbing of fingers 0.4865732632807997 0.4487506374317616 0.6536115514093757 1.0 0.8766825194930619 4 Q86TI2,P50851,O95453 3 +Duplication involving bones of the feet 0.336421617054618 0.4468737652301218 0.6549662070942923 1.0 0.8776962786732282 22 Q10713,O96028,O95202,P21964,Q14739 5 +Cryptorchidism 0.2429266118207843 0.4455561485272666 0.6559178925257618 1.0 0.8782116797333398 196 Q7LGA3,P61978,O14678,Q13423,O95202,Q6DKJ4,P98175,P21964,Q86XL3,P37268,Q99567,Q9Y619,Q9Y487,P46977,Q9Y4P3,P07437,Q9NVI7,P42858,O75648,Q06787,O15360,Q9UL01,Q13535,Q96PU5,P51114,O96028,O95470,P42345,Q8TAA9,P16435,P48651,Q8NAT1 32 +Polyhydramnios 0.2749839019861261 0.4437298361946933 0.65723792145901 1.0 0.8792189412895366 56 O75844,O43683,Q6PGP7,Q04446,Q99567,P36776,P51798,Q9ULH0,P27635,Q9UBM7,Q70HW3,Q9UM00,Q9NVI7,O43909,P21964,Q14739,P04062 17 +Relative macrocephaly 0.2875353728294668 0.4424869140356089 0.6581368976459219 1.0 0.8794820332541045 39 Q7LGA3,P42858,O75844,O75648,P48651,Q96PZ0,Q6DKJ4,Q15392 8 +Fibrous tissue neoplasm 0.3423526488915367 0.4392705910943683 0.6604654808744299 1.0 0.8815060684121233 19 Q15392 1 +Premature birth 0.2807537994684691 0.4363768183535856 0.6625633553224308 1.0 0.8830191404554555 41 O43676,P04062 2 +Primary adrenal insufficiency 0.3863673155353849 0.4362102046129354 0.6626842247480205 1.0 0.8830191404554555 13 Q13423 1 +Cavum septum pellucidum 0.4001199226458057 0.4361340062464032 0.6627395055463137 1.0 0.8830191404554555 11 O96028,Q14738 2 +Profound hearing impairment 0.4742050593848307 0.4347027724985042 0.663778185700175 1.0 0.8838960879229042 5 Q9NR77 1 +Episodic ataxia 0.4740918422201505 0.434278475095314 0.6640862326550216 1.0 0.8840226318093594 5 O14936 1 +Focal t2 hyperintense basal ganglia lesion 0.331763114870218 0.4339939110317866 0.6642928626923914 1.0 0.8840226318093594 23 O75306,P03886,Q96CU9,Q9P0J0 4 +Synostosis of carpals tarsals 0.416559019615265 0.4299530509450791 0.667229793555236 1.0 0.8856998916736076 8 Q96L58,P16435 2 +Carpal synostosis 0.416559019615265 0.4299530509450791 0.667229793555236 1.0 0.8856998916736076 8 Q96L58,P16435 2 +Inguinal freckling 0.3897316219369912 0.4278679194069792 0.668747284593673 1.0 0.8872072770480312 2 Q9H488 1 +Abnormality of hand joint mobility 0.4803210012115803 0.4260929826588004 0.67004009334068 1.0 0.8884150324374428 4 P48651 1 +Hyperextensibility of the finger joints 0.4803210012115803 0.4260929826588004 0.67004009334068 1.0 0.8884150324374428 4 P48651 1 +Abnormality of the pubic bone 0.462740935537559 0.4253341914218138 0.6705930719325699 1.0 0.8888945541223167 6 O96028,Q8IZA0 2 +Abnormal shoulder morphology 0.3002572034889026 0.4240104277001685 0.6715582084545184 1.0 0.889582705355792 32 Q7LGA3,P42858,O75648,Q6ZXV5,Q9Y619,Q96PZ0,Q96PU5,Q9Y4P3 8 +Decreased circulating iga level 0.3904755532276994 0.4212116276500068 0.6736005543801862 1.0 0.8909170365685138 12 Q13315,P42345,Q15904 3 +Tetraparesis 0.2852551141196872 0.4204668155359048 0.6741444665568439 1.0 0.8909170365685138 39 Q9H9P8,P17900,P07602,Q5JPH6,O95630,P35637,Q9UBX3,Q9NZJ7,Q8WVX9,P21912 10 +Abnormal connection of the cardiac segments 0.2734357820828857 0.4203844523038875 0.6742046242247628 1.0 0.8909170365685138 60 O75844,Q6PGP7,O15360,O15460,P01889,Q6DKJ4,Q15427,Q9UHX1,P98175,P21964,Q9Y4P3 11 +Ridged nail 0.437928133374374 0.4183290341347121 0.6757065644850941 1.0 0.8909468069128246 7 P16615 1 +Hypoplasia of teeth 0.3233066724208427 0.4179963206448808 0.6759498073430961 1.0 0.8909468069128246 25 O75844,P51648,P61586 3 +Aplasia hypoplasia affecting the fundus 0.3038073499082196 0.4177761261239446 0.67611080753221 1.0 0.8909468069128246 30 Q96KP1,P61978,Q00839,P37268,O14936,Q99519,Q9UHX1,Q9NVI7,P30153 9 +Exodeviation 0.332061339620211 0.4169629488860293 0.6767055087055991 1.0 0.8912600197455952 22 P55795,Q15233,Q8NI27,Q99496,Q9H2P0,P27635,Q9UEY8,Q9UHX1,Q10471,P40939,O43819 11 +Motor delay 0.2440223903651426 0.4156320196945564 0.6776792926013813 1.0 0.891525984496044 246 Q7LGA3,Q8TD16,P51970,P61978,Q15120,Q8TB36,P51798,Q92974,Q8WVX9,Q15907,Q99720,P00403,P04062,P49902,Q10713,Q9Y487,Q9NWM8,P10253,P07437,Q96N66,Q96D71,P04350,P42858,O75648,P55011,P03886,Q06787,Q9UL01,Q99519,Q96L58,P51114,O75569,O60313,P16435,O14936,Q6ZXV5,Q9Y366,P35637,Q13510,Q14376,Q96PZ0,Q8NAT1,Q5XKP0,Q4J6C6,Q14738,P51812,Q16836,Q9NR77,P35610,Q9NZ01 50 +Limb muscle weakness 0.2518181001278221 0.4152628758340518 0.6779494748660713 1.0 0.891525984496044 87 O15269,Q15120,P31483,Q96RL7,Q8TB36,Q13510,O15270,Q13126,P12235,Q99720,Q9NR77,Q9BQT8,Q14739,Q15067 14 +Limited elbow extension 0.3892913463675923 0.4152605107640988 0.6779512060319681 1.0 0.891525984496044 12 Q15427,P16435 2 +Neoplasm of the skeletal system 0.2815822451337576 0.4136478867843122 0.6791319976420929 1.0 0.8924921045387841 40 O75874,P48735,Q13126 3 +Diplopia 0.3340411418156477 0.4134701627204305 0.679262178572781 1.0 0.8924921045387841 21 P01889,O14773,P04062 3 +Abnormal jaw morphology 0.2334871474107438 0.4120301990333337 0.6803172886665294 1.0 0.8933603303625538 308 Q7LGA3,Q8TD16,O14678,O95630,P78318,P51798,P51571,Q13045,Q9Y4W2,Q9UM00,O95202,Q6DKJ4,Q15392,Q9UBN7,Q5SRE5,P98175,P21964,P04062,Q86XL3,O75844,Q2TAA5,Q15022,O43683,Q12768,P37268,P53701,Q99567,P16278,Q9Y619,Q9UPT5,O15228,Q15427,Q9Y4P3,P07437,Q9NVI7,Q8N201,Q6NUK1,P42858,O75648,P55795,P55011,Q06787,O15360,Q9NXE4,Q9UL01,Q96L58,Q13535,Q96PU5,O96028,O75845,Q16625,Q14739,Q00839,Q96RL7,P48651,O60762,O14936,Q9UBM7,Q9BT22,Q96PZ0,Q4J6C6,Q9UHX1,P51812,Q96MF7 64 +Abnormal vitamin b12 level 0.4363334093908581 0.4117811624215386 0.6804998297789664 1.0 0.8933603303625538 7 Q99707,O14678 2 +Abnormality of refraction 0.2498467888649742 0.410801521555908 0.6812180773894485 1.0 0.8937981326041734 161 Q7LGA3,P61978,Q92974,O15460,Q13045,Q15907,P98175,P49902,Q9Y487,Q9NWM8,Q9Y4P3,Q9NVI7,Q8N201,Q15067,Q6NUK1,P42858,O43292,O75648,P55011,O15360,P61586,Q9UL01,Q96L58,P12235,O14936,Q15904,Q9Y366,P51648,Q96PZ0,Q9UHX1,Q96A33,O60568,Q14738 33 +Abnormality of the phalanges of the toes 0.3354021758369457 0.4076023723848607 0.6835656223067632 1.0 0.8956080714330447 20 Q7LGA3,O75844,O15360,Q6DKJ4 4 +Eeg with spike wave complexes 0.3742753257477033 0.4066827445143301 0.6842410156056251 1.0 0.8956080714330447 14 Q14108 1 +Hyperactive deep tendon reflexes 0.4112507243720225 0.4064356101897294 0.6844225591385897 1.0 0.8956080714330447 8 P11166,Q9NR77 2 +Abnormal sclera morphology 0.3066661496103717 0.4057379540324179 0.6849351519362386 1.0 0.8956080714330447 29 Q96L58,O75718,Q96AY3,Q9UL01 4 +Hyperactive patellar reflex 0.4056457667907874 0.4053448173895929 0.6852240673551984 1.0 0.8956080714330447 9 P13073,P21912,Q15041 3 +Ankyloglossia 0.4109491608948898 0.4051117657943087 0.6853953582977825 1.0 0.8956080714330447 8 O75844 1 +Hydrops fetalis 0.2687207183783678 0.4050890370764815 0.6854120645779582 1.0 0.8956080714330447 46 P10619,P16278,P04062,Q13510,P08236,Q14739 6 +Vasculitis 0.3994321420694866 0.4031100683022167 0.686867254138845 1.0 0.8957795100053731 10 P01889,Q9NZ08 2 +Abnormality of ocular smooth pursuit 0.3272437178516652 0.4025184134832342 0.6873025397389374 1.0 0.8959102460777519 23 P46977,O14773,Q06787,Q10713 4 +Megaloblastic anemia 0.4102500780478459 0.4020479787804238 0.6876487166408229 1.0 0.8959102460777519 8 Q99707,P00374 2 +Advanced eruption of teeth 0.3859623426190378 0.3986566737331034 0.690146196255983 1.0 0.8989120347085217 12 O75844,Q9UBM7 2 +Inverted nipples 0.4326202592357396 0.3966623508149875 0.6916164670056959 1.0 0.9005745811963182 7 P61978,Q15067,Q2TAA5 3 +Chromosome breakage 0.3853304231099834 0.3955262578793663 0.6924545470871459 1.0 0.9010510841036364 12 P13073,Q06787 2 +Myelomeningocele 0.4712863185584414 0.3940596588880518 0.6935369937858542 1.0 0.901055054007013 4 O75845 1 +Infantile onset 0.2440811356517518 0.3935675377918993 0.6939003518970963 1.0 0.901275100618929 180 P51970,Q8TB36,Q5JPH6,Q9NP80,Q96CU9,Q8WVX9,Q70HW3,P06865,Q99707,P35658,Q9P0J0,Q2TAA5,O95831,P23786,Q9H9P8,Q96KP1,Q99797,Q10713,P07602,O75306,P11166,P78527,P28288,Q9NVI7,Q15067,O75746,O43292,Q9Y6M9,P55795,Q9NPL8,O75648,Q6NUQ1,Q9NZJ7,Q5JRX3,O00584,P42345,Q00839,O60762,Q6ZXV5,Q15904,O76031,Q5XKP0,Q9NR77,Q9Y320 44 +Childhood onset 0.2896978534150153 0.3915580314860327 0.6953848026018203 1.0 0.902262568877608 36 Q8TB36,P50402,Q5JRX3,P22830,Q14566,Q9NR77 6 +Finger syndactyly 0.2845260726085566 0.3870093547092877 0.6987492825082944 1.0 0.905547884667653 38 Q15022,Q12768,P48651,O15360,Q9Y366,Q9Y619,Q9UBM7,Q6DKJ4,Q15427,Q96EK5,P98175 11 +Nevus 0.2999590097732402 0.3861766317705405 0.6993658590880591 1.0 0.9058415894405136 30 Q6NUK1,P04049,Q15022,Q96AY3,Q99496,Q6DKJ4,Q9Y4P3,Q9UHX1,Q9UIG0,P21912 10 +Scleral staphyloma 0.4687682428488091 0.3852877798184213 0.7000242143126367 1.0 0.906441610840722 4 Q969N2,P40939,P36404 3 +Broad distal phalanx of finger 0.4296235171014416 0.3845936522079267 0.7005384978658162 1.0 0.9065726705198824 7 Q7LGA3 1 +Abnormality of subcutaneous fat tissue 0.3699508017783587 0.3838143980670726 0.7011160157971559 1.0 0.9065726705198824 14 O75844 1 +Submucous cleft soft palate 0.4231105923548416 0.3837057630790131 0.7011965406829128 1.0 0.9065726705198824 3 O14802,Q15233 2 +Patellar dislocation 0.3295239507389932 0.3836675629190056 0.7012248570682393 1.0 0.9065726705198824 21 Q6ZXV5,P21964,Q96PU5 3 +Megalocornea 0.3828503877014686 0.3833080964875094 0.7014913367453675 1.0 0.9065726705198824 12 Q9H9S5,O96028,O95202,Q9Y4P3,Q96EK5 5 +Decreased plasma carnitine 0.3760618114326673 0.382955530312479 0.7017527367933978 1.0 0.9066582911963644 13 O43772,P23786,Q16836,O75648 4 +Sclerosis of skull base 0.4675358777429794 0.3810203931274228 0.703188116378231 1.0 0.9071104647908318 4 Q14739 1 +Protuberant abdomen 0.4286442534592873 0.3806762622322811 0.7034434849836653 1.0 0.9071104647908318 7 P42345,P04062 2 +Right ventricular cardiomyopathy 0.4506425233645008 0.3794503359514195 0.7043534776340765 1.0 0.9077465345597556 6 P15924,Q99959,Q9BTV4,P14923,Q14126 5 +Inflammation of the large intestine 0.3620967559703635 0.3770624160359838 0.7061272209115685 1.0 0.90837793462474 15 P08183,P01889 2 +Abnormal arachnoid mater morphology 0.3936133648488957 0.3762655428827151 0.7067194930714775 1.0 0.90837793462474 10 Q9UHX1,Q14738 2 +Abnormal urine metabolite level 0.2470709493812149 0.3761222255687929 0.7068260318330966 1.0 0.90837793462474 166 O14678,P36551,P53985,P06280,Q16134,Q99707,P08236,P00403,P04062,P23786,P16278,Q9Y619,P00367,Q9UJS0,Q9Y4P3,P10253,Q96EY8,P09601,Q14108,P21912,Q9NVI7,Q02978,P03886,P15586,Q99519,O95470,P54802,P23378,Q8N1F7,Q9UBS4,Q92621,Q86YH6,P52429,O96000,Q12769,O14936,Q8NFH4,Q6PGP7,Q14376,Q96MF7,Q5XKP0,Q4J6C6,Q16836,P35610 44 +Paranoia 0.4581233161982798 0.3758339108785544 0.7070403756717984 1.0 0.90837793462474 5 Q96RL7 1 +Thoracic aortic aneurysm 0.2832773331223558 0.3754109708318526 0.7073548470193898 1.0 0.90837793462474 38 Q7LGA3,P42858,O75844,O75648,Q06787,Q96L58,P01889,Q9Y4P3 8 +Supernumerary tooth 0.4273135027607199 0.3753739503568043 0.7073823754699813 1.0 0.90837793462474 7 Q6DKJ4,Q9UBM7,Q9UHX1 3 +Abnormality of the ovary 0.2667632738167974 0.3753702305881818 0.7073851415136265 1.0 0.90837793462474 67 O75844,O75874,P16435,P48735,Q06787,Q01844 6 +Abnormality of the shoulder girdle musculature 0.2877203085491499 0.3737999402034031 0.7085531639887768 1.0 0.9093751380916733 36 P07602,Q9NZJ7,O14979,Q9Y487,P12235,O60313 6 +Otitis media 0.2693597813719288 0.3710769053793259 0.7105802518142532 1.0 0.9114731777827224 61 Q06787,P51798,Q13045,O96028,O95202,Q6DKJ4,Q9Y4P3,Q03519,Q96A33,Q03518,P21964,Q8N5M9,Q14739 13 +Severe short limb dwarfism 0.464427931140422 0.3703344230112061 0.7111333283575378 1.0 0.9115195267918794 4 Q14739 1 +Adducted thumb 0.3098521457901907 0.369894641175338 0.7114609944350161 1.0 0.9115195267918794 27 Q9UL01,Q9Y4P3,P42892,Q86XL3 4 +Apraxia 0.2628481159399184 0.3697940752780048 0.7115359300613795 1.0 0.9115195267918794 70 Q7LGA3,O43292,O14773,P35637,Q9Y619,P05067,Q6DKK2,P04062 8 +Abnormality of the hypothalamus pituitary axis 0.2562267314092789 0.3696624320619772 0.7116340268382226 1.0 0.9115195267918794 75 O75874,Q10713,O76024,P16435,P48735,O15360,Q06787,Q4J6C6,Q9UHX1,Q96MF7 10 +Short chin 0.3799434865084326 0.3691269477259759 0.7120331037089795 1.0 0.9115195267918794 12 O75844,P42345,Q96J02 3 +Inflammatory abnormality of the eye 0.2769618637493838 0.3689218974324111 0.7121859410793203 1.0 0.9115195267918794 40 P51648,P04439,Q15800,Q9NZ08,Q14739 5 +Bundle branch block 0.3308985225135202 0.3666400314056723 0.7138875437967116 1.0 0.9131942534359916 19 P46976,Q9HD47,Q99959,Q14BN4,P06280,Q9H490 6 +Osteomyelitis 0.3591800511427546 0.3613980989504755 0.7178018689257761 1.0 0.9169711871572064 15 O15269,O15270,Q13126 3 +Inappropriate crying 0.4231640919591093 0.359000184794103 0.719594951031431 1.0 0.9189769495580068 7 P07602 1 +Pseudoepiphyses of hand bones 0.4443724401481857 0.3563701892584484 0.7215633513625637 1.0 0.9198219136425674 6 O96028,O95202 2 +Multiple rows of eyelashes 0.4152319813247864 0.3545257441036528 0.7229449142675333 1.0 0.920724252107171 3 Q9Y606,O60716 2 +Increased vertebral height 0.4151562840356826 0.3542496355970221 0.7231518084063238 1.0 0.9207353526598464 3 Q96J02 1 +Abnormality on pulmonary function testing 0.3220932757923433 0.3503427886910846 0.7260814567907548 1.0 0.9232004510809652 22 Q96L58,P16278,Q9BQT8 3 +Menorrhagia 0.4579684378495849 0.348482869788742 0.7274775764885633 1.0 0.9242321245065463 4 P49257 1 +Abnormality of krebs cycle metabolism 0.4503494626583432 0.3484542386579657 0.7274990750945503 1.0 0.9242321245065463 5 P03886 1 +Abnormality of thyroid physiology 0.2453639857466105 0.3480411843716379 0.7278092540588317 1.0 0.9242321245065463 81 P61978,O76024,Q6PGP7,P03886,Q06787,Q13045,Q13423,O95470,Q9Y4P3,P12235,P21964,O60313,P00403 13 +Abnormal erythrocyte sedimentation rate 0.3871691332069921 0.3472001563349654 0.7284409533987262 1.0 0.9246821501340114 10 P01889 1 +Symphalangism of middle phalanx of finger 0.3696032672112023 0.3450743055047185 0.7300385096252873 1.0 0.92595110994242 2 Q15233 1 +Motor seizure 0.2494664383999284 0.3443709634133298 0.7305673227837066 1.0 0.9261161750758802 113 O43292,P07602,P03886,P16278,O75503,Q9Y619,Q9UBX3,Q9NZJ7,Q99519,Q13510,Q96N66,P04062 12 +Abnormality of the urinary system physiology 0.2354678657609203 0.3410141696829117 0.7330929145720781 1.0 0.9288109302159464 288 O14678,P48735,Q96CU9,O15460,P53985,Q13423,P06280,O43676,Q99707,P08236,Q9BQT8,P00403,P04062,O75306,P23786,Q10713,Q86Y39,P16278,Q13277,Q9Y619,Q9NWS8,Q9Y4P3,P10253,Q9NZ08,Q96EY8,P09601,Q14108,Q9NVI7,Q9Y6M9,Q9NPL8,P03886,O15360,P15586,Q99519,O95470,P54802,P12235,O43772,Q16625,P23378,Q8TAA9,Q12769,P52429,O76024,Q6PGP7,Q14376,Q9BT22,P01889,Q4J6C6,P35610 50 +Abnormality of the skull base 0.2627966589391008 0.3402951025319007 0.7336343049400886 1.0 0.929139722507839 68 P23786,Q9NPL8,Q10713,Q99567,Q9Y487,Q96L58,Q8NAT1,Q9UHX1,P07437,Q14739 10 +Focal onset seizure 0.2470993053785316 0.339872714833734 0.7339523851923739 1.0 0.929139722507839 89 P07602,Q9NP80,P03886,Q6ZXV5,O75503,Q9UBX3,Q9NZJ7,Q96PU5,Q96N66,P00403 10 +Hyperpigmentation of the skin 0.2488188522689244 0.3393157160452887 0.7343719045146591 1.0 0.9291644521718698 99 O75844,Q7LGA3,Q06136,P42345,P42858,O75648,P53701,Q6PGP7,O15360,P51648,P16615,Q13315,Q13423,P07437,Q14739,P04062 16 +Dicarboxylic aciduria 0.3122181169521471 0.3388361814752204 0.7347331430045994 1.0 0.9293684133948732 25 P23786,O14678,P48735,Q16134,Q16836,O43772,Q96EY8 7 +Pterygium 0.3734723830702982 0.3381243051275021 0.7352695152557862 1.0 0.9295407259533016 12 Q99567 1 +Cerebral hemorrhage 0.3609707134537231 0.3375035895227478 0.7357373066769544 1.0 0.9296765171632424 14 P23786 1 +Secondary microcephaly 0.2506927845488748 0.3347724720791641 0.7377967275820421 1.0 0.9311049732590518 77 Q96KP1,P55795,O60762,O14936,O95630,Q86Y39,P00374,Q96CU9,Q9NXE4,Q8WVX9,P49770,Q9Y487,Q9BT22,Q5XKP0,P50897,Q9UHX1,Q15043 17 +Preauricular skin tag 0.3332362142619892 0.3343570838397474 0.7381101197832733 1.0 0.9311049732590518 18 Q15427,O96028,Q12768,O95202 4 +Metaphyseal cupping 0.4461261307676657 0.333895442665281 0.73845845886224 1.0 0.9312915309104144 5 Q14739,O95831 2 +Mesomelia 0.3939262669940473 0.3326672351402933 0.739385484715894 1.0 0.931954683122638 8 Q14739,Q6DKJ4 2 +Abnormal blood glucose concentration 0.2477231468603937 0.331363710535405 0.7403697727349061 1.0 0.9329422197250812 95 O75844,P23786,Q9Y6M9,Q9NPL8,P42345,O75306,Q86Y39,P03886,Q96CU9,P53985,Q13423,Q4J6C6,O43676,O95470,O43772,P35610,Q14738 17 +Dysplastic corpus callosum 0.3654618357402061 0.3302463721758433 0.7412138105385788 1.0 0.933499420916844 13 P49902,Q9NVI7 2 +Elevated lactate pyruvate ratio 0.4518420930581772 0.328221645514308 0.7427440828306702 1.0 0.935173173125012 4 O96000 1 +Abnormality of the calvaria 0.2359301644633357 0.3273379104940351 0.7434123219641702 1.0 0.9357609449595056 283 P61978,P11177,P51798,Q13045,Q9UM00,Q9UBN7,Q16134,O95202,Q15392,Q6DKJ4,P98175,P21964,P04062,O95831,O75844,Q32P28,O43683,Q12768,Q10713,P16278,Q9Y619,Q9Y487,O15228,P07437,Q9NVI7,Q8N201,Q15043,Q6NUK1,Q15067,Q06787,O15360,P15586,Q9UL01,Q99519,Q96L58,Q13535,P13073,O96028,O75845,P54802,P22626,O75718,Q14739,P42345,Q00839,Q96AY3,P16435,O60762,O14936,P48651,Q9Y366,Q6PGP7,Q9UBM7,Q9BT22,Q4J6C6,P51812,Q96A33,Q14738 58 +Abnormal erythrocyte morphology 0.2378652994267501 0.3257273182155752 0.744630673521848 1.0 0.9360265446922365 200 O75874,O14678,P48735,P51798,Q9UBX3,Q96CU9,P06280,Q01844,Q99707,Q9BQT8,Q9P0J0,P00403,P04062,O75306,P07602,P22830,Q96EY8,P09601,Q14108,P03886,O15360,P00374,Q9NZJ7,O75845,P52429,Q96RL7,O76024,Q6P4A7,Q15904,P01889,Q96MF7,Q13510,O76031,O60313 34 +Kinetic tremor 0.2723744578564677 0.3254075393149502 0.7448726502095364 1.0 0.936077450060456 40 Q06787,Q9Y287,P07602,Q14108 4 +Abnormality of the nasal bone 0.4433936260304315 0.324598576731831 0.7454849045555978 1.0 0.9360872612338668 5 Q6NUK1,P35222,O14974 3 +Abnormal tracheobronchial morphology 0.2591766293515998 0.3239420051265465 0.7459819417094533 1.0 0.9362053217671852 70 P55011,Q96HY6,P16435,Q13277,O15360,P30154,Q13045,Q13315,Q96L58,Q03519,Q9Y4P3,Q9H0U3,Q03518,Q14739 14 +Abnormality of retinal pigmentation 0.2512891090494366 0.3233348206100725 0.7464416860016256 1.0 0.9362764776359483 76 P18074,Q96CU9,Q7KZN9,Q96S66,P00403,Q9P0J0,O75306,P53701,P21912,Q15067,P03886,Q9H9S5,Q6P4Q7,Q6P2Q9,Q9UG56,O76024,P40855,P51648,O15078,P51812,Q16836 21 +Premature skin wrinkling 0.3200439331320083 0.3228428803589527 0.7468142365406967 1.0 0.9363149617396171 21 O75844 1 +Abnormality of fibula morphology 0.3638707933956899 0.3225313092935089 0.747050222572222 1.0 0.9363149617396171 13 Q13535,Q15427,P16435 3 +Multifactorial inheritance 0.3517264675498314 0.3222016963967112 0.7472998994238174 1.0 0.93634178336652 15 P01889,P42892 2 +Lipoma 0.4424103325513125 0.3212771161194092 0.7480003966268272 1.0 0.9365828606179132 5 Q8TAA9,P21912 2 +Abnormal sputum 0.4132858619592642 0.3210338639617919 0.7481847283193952 1.0 0.9365828606179132 7 Q9NZ08 1 +Cloverleaf skull 0.4495586926534449 0.3207892347034931 0.7483701180696096 1.0 0.9365828606179132 4 O43909,P16435 2 +Craniosynostosis 0.2606043657355126 0.3199829283287727 0.7489812719577635 1.0 0.9369324150554036 46 Q6NUK1,P61978,P16435,Q9Y366,P51798,Q9Y619,Q9UL01,Q96L58,Q13535,P21964 10 +Gastrointestinal obstruction 0.3572527329270822 0.318825700739101 0.7498586881591145 1.0 0.9377775141823004 14 Q5HYI8,P42892,Q01844 3 +Slender finger 0.2793979246329061 0.3171595391585672 0.7511225492792366 1.0 0.93860015168137 37 P55795,P16435,Q9UL01,Q96L58,O96028,P21964 6 +Urticaria 0.3688958753576249 0.3166936409047918 0.7514760744468214 1.0 0.9387894170153084 12 P49327,P21912,P51648,Q15427 4 +Periauricular skin pits 0.3685144583855713 0.3149267922753196 0.7528172386005041 1.0 0.9395174035981616 12 P61978,O96028 2 +Aphthous ulcer 0.4116201110655046 0.3147783379666385 0.752929960058581 1.0 0.9395174035981616 7 P78527,Q9NZ08,P01889 3 +Ovarian cyst 0.3502515411506998 0.3145940307713884 0.7530699119671878 1.0 0.9395174035981616 15 Q9Y4P3,P16435 2 +Very long chain fatty acid accumulation 0.4474449777173745 0.3139682281950873 0.7535451697067657 1.0 0.9398317262047704 4 O75381,P40855 2 +Abnormal muscle glycogen content 0.4397181883545595 0.3122493389476368 0.7548510381288498 1.0 0.9398317262047704 5 O75648 1 +Bronchiectasis 0.3082519319498809 0.3114087668933558 0.7554898900030274 1.0 0.9398317262047704 25 Q13315,Q03518,Q13277,Q03519 4 +Viral hepatitis 0.446584938704034 0.3112093023423703 0.7556415116904094 1.0 0.9398317262047704 4 Q9NWH9,P35222,P11717 3 +Subacute progressive viral hepatitis 0.446584938704034 0.3112093023423703 0.7556415116904094 1.0 0.9398317262047704 4 Q9NWH9,P35222,P11717 3 +Broad forehead 0.2762294475408187 0.3111494205883181 0.7556870322553986 1.0 0.9398317262047704 38 Q6NUK1,Q15022,Q12768,P48651,O14936,P78318,Q6PGP7,P27635,Q07864,Q13045,Q9Y4P3,Q9H490,P54886 13 +Hand muscle weakness 0.3734892560003438 0.3110674869092952 0.7557493174991439 1.0 0.9398317262047704 11 Q9NR77,Q15120,P31483 3 +Blepharophimosis 0.2627177198394934 0.3104723651603503 0.7562017713022064 1.0 0.9398912331380554 54 Q7LGA3,O75844,P42858,O75648,Q9Y619,P61586,Q13535,Q9Y4P3,P07437,P38159 10 +Obstructive sleep apnea 0.3607687919810545 0.3076450196146658 0.7583524597737115 1.0 0.9419094341535352 13 P51114 1 +Abnormal aortic arch morphology 0.36691232659223 0.3075382045751509 0.7584337479914713 1.0 0.9419094341535352 12 Q9UHX1 1 +Cyanosis 0.3194313846517647 0.3071380599800332 0.7587382891504635 1.0 0.9419714502843324 20 O75844,O43772,Q00325,P51812,P98175 5 +Abnormal greater sciatic notch morphology 0.4381210674264976 0.3069398164674273 0.7588891817508086 1.0 0.9419714502843324 5 P08236 1 +Pituitary prolactin cell adenoma 0.3591015169194915 0.3047111814001015 0.7605861328376153 1.0 0.9420867264225904 2 P10644 1 +Elevated circulating growth hormone concentration 0.3591015169194915 0.3047111814001015 0.7605861328376153 1.0 0.9420867264225904 2 P10644 1 +Sudden loss of visual acuity 0.3591015169194913 0.3047111814001006 0.760586132837616 1.0 0.9420867264225904 2 P35222 1 +Torsion dystonia 0.4445285129735067 0.3046514351372171 0.7606316413748735 1.0 0.9420867264225904 4 P04350 1 +Short thorax 0.4296535572290408 0.3042355200635868 0.7609484655016459 1.0 0.9420867264225904 6 P11166,Q9Y366,Q9P2L0,Q99519 4 +Lipid accumulation in hepatocytes 0.2586954635415393 0.3039132262932636 0.7611940009897138 1.0 0.9420867264225904 69 P23786,O75648,Q6NUQ1,Q5JPH6,O60762,Q15904,Q7KZN9,Q96MF7,Q9UJS0,Q5XKP0,Q16134,Q9NWS8,P22626,O43772,Q8N511,Q16836,Q9BW92,Q15067 18 +Schizencephaly 0.358809801633603 0.3036200418389304 0.7614173808000466 1.0 0.9420867264225904 2 Q9BVA1 1 +Right bundle branch block 0.3478151861163016 0.3021394220310289 0.7625457814629462 1.0 0.9423885147397304 15 Q9HD47,Q99959,Q9H490,Q14BN4 4 +Petechiae 0.3595749980838156 0.3019719541768705 0.7626734428371473 1.0 0.9423885147397304 13 Q16625,P04062,Q99519 3 +Cerebral cortical atrophy 0.2466466890501109 0.3006335458041397 0.7636939482755039 1.0 0.9429073388050644 113 Q7LGA3,P42858,P51970,O75648,O76024,Q96RL7,P03886,O75503,Q06787,Q9Y619,P05067,Q9UPT5,Q9NWS8,Q9Y4P3,Q16625,P00403,P04062 17 +Abnormality of the scrotum 0.2613415887497968 0.3005452618241707 0.7637612772260733 1.0 0.9429073388050644 52 Q7LGA3,Q6NUK1,P42858,O75648,P55011,P16435,Q9Y619,Q9UBM7,Q96PZ0,P46977,Q9UM00,Q8TCJ2,P07437 13 +Heterochromia iridis 0.3579346557759639 0.3003566481108005 0.7639051276931257 1.0 0.9429073388050644 2 Q8IY17 1 +Hyperlipoproteinemia 0.3706814728848275 0.2986490745984911 0.7652078171220098 1.0 0.9438479850622584 11 Q8WXH0,P34913,P50402,Q9UJS0,Q8N511 5 +Abnormality of the middle ear 0.2447430401478494 0.2978202147416369 0.7658403851441093 1.0 0.9438479850622584 141 Q7LGA3,P61978,P51798,O15460,Q13045,O95202,Q6DKJ4,Q9H0U3,P21964,O95831,O75844,Q9NWM8,Q15427,Q9Y4P3,Q6NUK1,P42858,O75648,Q06787,Q96L58,O75845,O96028,Q03519,Q03518,Q14739,P16435,P01889,Q96PZ0,Q96A33,Q8N5M9 29 +Abnormality of facial musculature 0.2425855367642177 0.2955768224680179 0.767553276131359 1.0 0.9446595595107962 84 P10253,P48651,Q9UL01,Q9UHX1,Q14738,P12235,Q15907,Q13510,Q9BQT8,P04062,Q15043 11 +Gonosomal inheritance 0.2619804616924659 0.2937404085642134 0.7689562741288052 1.0 0.9458752580361208 65 Q15120,P78318,P51571,Q9Y4W2,P06280,Q9UBN7,Q9H0U3,P98175,O95831,P53701,P50402,P51572,P55795,Q9NVH6,Q06787,P38159,O14936,Q15904,P27635,P13473,P51812 21 +Abnormal glomerular mesangium morphology 0.3259741081605794 0.2926846200380723 0.7697632267853094 1.0 0.9461022584747538 18 Q12769,Q92621,Q8NFH4,O95470,O43707,Q8N1F7 6 +Aplasia hypoplasia of the hallux 0.3130724150146193 0.2924332774674201 0.7699553679063806 1.0 0.9461022584747538 22 Q7LGA3,P42858,O75648,Q96PZ0,O96028,O95202,Q9UHX1 7 +Limb tremor 0.4051823476767832 0.2910185609454215 0.7710371240055025 1.0 0.9469306048452456 7 Q9NR77 1 +Abnormal facial expression 0.2798995395894512 0.2904079863269254 0.7715041346452998 1.0 0.9472537551696784 35 Q9NR77,Q06787,P04062,Q15043 4 +Aplasia hypoplasia of the cerebellum 0.2442030561399412 0.2886909089840402 0.7728179202175869 1.0 0.9483655724592998 151 Q8TD16,P11177,Q8WVX9,Q9UM00,Q9UBN7,O95202,Q15907,P98175,P23786,Q9H9P8,Q96KP1,O43683,Q12768,Q10713,Q99567,Q9UPT5,Q9Y487,P07437,Q9NVI7,Q8N201,Q6NUK1,O43292,P55795,P00374,Q9NXE4,Q13535,O96028,Q16625,O14936,Q8NFH4,Q9UBM7,Q8NAT1,Q5XKP0,Q03154,P51812,Q9H490 36 +High pitched voice 0.3507161068553784 0.286742265149104 0.7743096729309931 1.0 0.949694493251688 14 O75844 1 +Abnormal circulating protein concentration 0.243749973620318 0.2839607027567896 0.776440496160943 1.0 0.9513034138090036 154 Q15120,P53985,Q13315,Q8N511,O95831,P23786,Q9Y487,P50402,Q9NWM8,Q9Y4P3,P10253,O75648,P31483,Q5JRX3,O95470,P22626,P12235,O43772,Q12769,Q96RL7,Q6PGP7,Q6ZXV5,P13473,O14979,Q8NAT1,Q9Y584 26 +Diffuse mesangial sclerosis 0.3310061610679403 0.2821234452839642 0.7778488563849937 1.0 0.9523877811320036 17 Q12769,Q92621,Q8NFH4,O95470,O43707,Q8N1F7 6 +Optic nerve hypoplasia 0.3134359915232498 0.2819681092229062 0.7779679636700392 1.0 0.9523877811320036 21 P61978,P37268,O14936,Q9UHX1,Q9NVI7,P30153 6 +Demyelinating peripheral neuropathy 0.3300614983427934 0.2770610562976551 0.7817332242280355 1.0 0.9550356025367466 17 P03886 1 +Turricephaly 0.365702397600222 0.2770281631524886 0.7817584810443385 1.0 0.9550356025367466 11 P21964,P16435 2 +Respiratory tract infection 0.2401713622022694 0.2759343986982656 0.7825984528317362 1.0 0.9551339740585184 173 P51798,O15460,Q13315,O95202,Q6DKJ4,Q9H0U3,P08236,P04062,Q12768,P07602,P16278,Q13277,Q9Y487,Q9UJW0,Q9Y4P3,P10253,P09601,Q16637,Q6NUK1,Q9NPL8,P15586,Q9NZJ7,Q99519,O96028,Q03519,P54802,Q03518,Q8N1F7,Q12769,P01889,Q13510,Q8N5M9 32 +Microphallus 0.428550630143919 0.2758664079185036 0.7826506756867799 1.0 0.9551339740585184 5 Q9UNW1,Q9Y4A5 2 +Narrow palpebral fissure 0.3156551691011081 0.275215176854128 0.783150927592865 1.0 0.9554117258962364 19 O75648,Q03164,Q9H2P0,P27635,O95613,Q8IWS0,Q8N201,P38159 8 +Poor fine motor coordination 0.3789399046080961 0.2729838180819755 0.7848656546249939 1.0 0.9558096468163498 8 Q06787 1 +Gait imbalance 0.3098609512920908 0.272423787922761 0.7852961840150803 1.0 0.9558096468163498 22 Q9NR77,O15269,O15270,Q9Y4P3 4 +Aspiration 0.3645950892934346 0.2722913152955488 0.7853980334266999 1.0 0.9558096468163498 11 P17900 1 +Spinal deformities 0.3999356576060418 0.2721599849055474 0.7854990082744475 1.0 0.9558096468163498 7 Q9H9S5,Q9Y5W7,Q8TB36 3 +X linked dominant inheritance 0.307292306562699 0.2702812420980601 0.7869438951536882 1.0 0.9571050620115276 23 P55795,Q15120,P53701,O14936,Q06787,P13473,P51812 7 +Excessive daytime somnolence 0.3413550326252774 0.2698166000630558 0.787301351312192 1.0 0.957289211776091 15 P42858,Q99496,Q99567,Q9H9S5,Q9UBM7,P35610 6 +Overriding aorta 0.3776730291219063 0.268130743870529 0.7885986817973898 1.0 0.9582401338905168 8 P53701 1 +Cerebellar cyst 0.2553477073271499 0.2667188666450165 0.7896856265067853 1.0 0.9591841622877187 46 P23786,O43683,Q12768,Q9Y5W7,Q99567,P36776,Q9H9S5,Q9UBM7,Q9Y487,Q8WVX9,Q8NAT1,O43505,P07437 13 +Sandal gap 0.2953795591867936 0.2652534372557455 0.7908142317199613 1.0 0.9603039520572244 27 Q15022,O60762,P61586,Q96L58,Q13535,Q6DKJ4,Q14739 7 +Abnormal basal ganglia mri signal intensity 0.2828697949508093 0.2648901022077154 0.7910941233594895 1.0 0.9603292427004494 31 O75306,P03886,P16278,Q96CU9,Q9P0J0 5 +Abnormal fingertip morphology 0.2845030217072251 0.2644214830858466 0.7914551593413734 1.0 0.9603292427004494 30 Q7LGA3,P42858,O75844,O75648,P55795,Q96PZ0 6 +Polycystic kidney dysplasia 0.3337483905344595 0.2624559444993773 0.7929699463143283 1.0 0.9614139797955036 16 Q6PGP7,P23786,P21964 3 +Abnormality of the cerebral subcortex 0.2274518980246134 0.2614989719370873 0.7937077422216485 1.0 0.9616684489953256 396 P11177,O95630,Q9UBX3,Q7KZN9,Q13045,Q15392,P00403,P04062,P23786,Q15022,O43683,P07602,P16278,Q9Y619,O43681,Q96D71,Q6NUK1,P17900,P55011,P03886,Q00839,O14936,O75503,Q9Y366,Q9UBM7,Q8NAT1,Q13885,Q9UHX1,Q03154,P51812,Q9H490,Q9Y320,Q9NZ01,Q7LGA3,Q8TD16,Q5JPH6,P78318,Q8WVX9,Q9UM00,Q5SRE5,Q9P0J0,Q86XL3,P49902,Q9H9P8,Q96KP1,P37268,P53701,P11166,P78527,Q9NWS8,Q96EK5,Q96N66,P21912,Q15043,P51572,Q96PU5,P12235,Q6ZXV5,Q14738,Q96CU9,P98175,Q2TAA5,Q10713,P10253,P07437,Q15067,Q9NZJ7,Q13535,O96028,P42345,Q96RL7,P48651,Q96A33,O60313,P51970,P61978,P51571,O95202,O95831,O75306,Q9UPT5,P42695,Q9NVI7,P42858,O75648,P23378,O00584,Q9BW92,Q96PZ0 89 +Muscle fiber necrosis 0.3471411901983632 0.261378290715767 0.7938007967923104 1.0 0.9616684489953256 2 Q96RR1 1 +Contractures of the large joints 0.3878027429238542 0.2602459683190852 0.7946740478850651 1.0 0.9617232681620248 3 Q9Y263,O75431 2 +Overweight 0.4161799065420674 0.2592401673748573 0.795449941052536 1.0 0.962255187784441 6 Q01082,Q93009,Q8NI27,O00330,P49748 5 +Abnormality of the helix 0.2562894499387719 0.2578756725474916 0.7965028605149316 1.0 0.9624308995770884 43 Q7LGA3,P23786,O75844 3 +Dyskinesia 0.2512401421870355 0.2556247745719942 0.7982405864912883 1.0 0.9636592846060054 72 Q96RL7,P03886,Q9UBX3,O75569,P04062,Q96N66,P35610,Q9P0J0,Q15043 9 +Abnormality of the humerus 0.3440158805465322 0.2549125216334102 0.7987906648208045 1.0 0.9636929183997552 14 O15228,P16435 2 +Ectropion 0.3492240253931067 0.25414739667594 0.79938168788247 1.0 0.9638565234098064 13 P04062 1 +Abnormal size of the palpebral fissures 0.2427476467242522 0.2508007890201338 0.8019681315204443 1.0 0.9645738857397262 99 Q7LGA3,P61978,Q6DKJ4,P98175,O75844,Q9Y619,Q9Y4P3,P07437,Q8N201,Q6NUK1,P42858,O75648,P55011,P55795,O15360,P61586,Q13535,P38159,Q96PZ0,Q9UHX1 20 +Pancreatitis 0.3058408837105658 0.2478584735484416 0.8042439107752206 1.0 0.9663877594936991 22 P03886,Q9NZ08,P00403,P01889 4 +Vertigo 0.2986376315524484 0.2471243909713199 0.8048119577667889 1.0 0.9663877594936991 25 P46976,Q02978,O15460,P01889,P06280,Q9NZ08,P21912 7 +Molar tooth sign on mri 0.4123558482450705 0.2469783881552745 0.8049249498054025 1.0 0.9663877594936991 6 O15078,Q96KP1,Q10713 3 +Cirrhosis 0.2712029089659338 0.2463213618964901 0.8054334748852121 1.0 0.9665656534598406 37 Q10713,Q6PGP7,P22830,P04062,Q14108,Q14739 6 +Non hodgkin lymphoma 0.3673656141272606 0.2447412591709953 0.8066567791341821 1.0 0.9665656534598406 9 Q9H0U3,Q13315,P49327,Q07864 4 +Abnormality of tibia morphology 0.3302119187400145 0.2446995371044848 0.8066890864846308 1.0 0.9665656534598406 16 Q32P28,P16435 2 +Aplasia hypoplasia involving the metacarpal bones 0.2924059807684089 0.2446920475477665 0.8066948860341452 1.0 0.9665656534598406 27 Q32P28,Q14739,P16435 3 +Genu varum 0.3626134755761455 0.2436386044316646 0.8075107270376185 1.0 0.9665656534598406 10 Q9Y619 1 +Spondylolisthesis 0.3415985997666252 0.2423092247023305 0.808540566451275 1.0 0.9671677321659692 2 O00754 1 +Impairment of activities of daily living 0.2575964956131805 0.2419730415555681 0.8088010523087659 1.0 0.9672302931857212 59 O15269,Q8TAA9,Q12768,P07602,O15270,Q06787,P35637,Q9NZJ7,Q8WVX9,O43681,P51812,Q99720,P21964 13 +Patellar hypoplasia 0.3410151691948644 0.2403405826507103 0.810066236411666 1.0 0.968244850622228 2 Q9H1A4 1 +Metaphyseal dysplasia 0.3616652674707499 0.239889568847675 0.8104158676376614 1.0 0.9684000421462164 10 Q99575,P36776,Q07864,Q9UBN7,O95831 5 +Recurrent 0.3805077327108457 0.2372689840751541 0.8124481222646174 1.0 0.969587110265426 3 P11182,P21953 2 +Thoracolumbar scoliosis 0.3896710895981534 0.2366439257529899 0.8129330400743331 1.0 0.969587110265426 7 P78318,Q99575,P27635 3 +Abnormal middle phalanx morphology of the hand 0.3607961476923529 0.2364706854694793 0.8130674519143564 1.0 0.969587110265426 10 P48651,Q03164,Q8IWS0,Q9UHX1 4 +Acidemia 0.3397721635906252 0.2353371648327412 0.8139470516356622 1.0 0.9701380199844244 14 Q96EY8,P48735,Q16134,O14678 4 +Abnormal aldolase level 0.4195254270196171 0.2295574442404017 0.8184356783337208 1.0 0.9736978956726672 4 O43505,Q8NAT1 2 +Abnormal macroscopic urine appearance 0.3045721983323078 0.2293326052408884 0.8186104133657852 1.0 0.9736978956726672 21 P23786,Q92621,Q12769,P36551,Q8NFH4,O43707,Q8N1F7 7 +Aplasia hypoplasia of the nasal bone 0.4190253556684893 0.2281473692920445 0.8195316756223532 1.0 0.9739223437975804 4 Q6NUK1,O14974 2 +Abnormality of circulating glucocorticoid level 0.348761111851101 0.2277910339057749 0.8198086973791572 1.0 0.9739223437975804 12 Q13423 1 +Abnormal cns myelination 0.2406053450294975 0.2249231091659498 0.8220390913565379 1.0 0.974625569233448 148 Q7LGA3,Q8TB36,Q96CU9,Q7KZN9,Q8WVX9,O43676,Q5SRE5,Q99720,Q9P0J0,O95831,O75306,Q9H9P8,Q96KP1,P07602,Q86Y39,P49770,P78527,O43681,Q9NWS8,P10253,P21912,Q15067,O75746,P04350,Q9Y6M9,Q9NPL8,P03886,Q9NXE4,Q9NZJ7,Q9Y584,O00584,O96000,P35637,P51648,P14854,Q03154,Q9H490 37 +Carcinoma 0.4113868613138736 0.2235112532390755 0.8231376258307912 1.0 0.974625569233448 5 P51532,O60832,Q07864,P28340 4 +Deviation of the hallux 0.2717184868183878 0.2232055139706196 0.8233755606660533 1.0 0.974625569233448 35 Q7LGA3,P42858,O75648,Q96L58,Q96PZ0,Q15427,Q9Y4P3,P04062 8 +Enlarged metaphyses 0.335764294049008 0.2229606563601882 0.8235661274058246 1.0 0.974625569233448 2 O43909 1 +Abnormality of upper limb metaphysis 0.3357642940490067 0.2229606563601842 0.8235661274058277 1.0 0.974625569233448 2 Q9H1A4 1 +Abnormal circulating androgen level 0.3369339902021421 0.2225087770583277 0.8239178414163075 1.0 0.974625569233448 14 Q13423 1 +Supraventricular arrhythmia 0.3062032710060953 0.222037871977277 0.8242844015085877 1.0 0.9747073884980654 19 P50402,Q99959,Q9HD47,P12235 4 +Abnormal circulating porphyrin concentration 0.4165518540774463 0.221228094005804 0.8249148352951856 1.0 0.9752046627942575 4 P22830 1 +Limb girdle muscle atrophy 0.3414618192671418 0.219985178417944 0.8258826978819189 1.0 0.9757265313607916 13 P09651,Q8WXH0,Q9H9S5,O14979,P50402 5 +Amblyopia 0.3251397850318315 0.2198521271002141 0.8259863211024523 1.0 0.9757265313607916 16 Q9UHX1 1 +Abnormal fear anxiety related behavior 0.2404294270966334 0.2188614124758194 0.8267580061040571 1.0 0.9761417271561498 122 Q7LGA3,P36551,Q15165,Q13045,Q9UM00,P06280,P21964,P00403,P11166,Q9Y4P3,P21912,P42858,P17900,O75648,P55011,P55795,P03886,P43243,Q06787,Q6DKK2,P12235,Q92804,O76024,Q96RL7,O75503,P35637,Q96PZ0 27 +Abnormal corpus striatum morphology 0.318507462241776 0.2172240895000748 0.8280337121624235 1.0 0.976870668373206 17 O75306,Q96RL7,O95831 3 +Abnormal liver physiology 0.4015714834430072 0.2136760648690862 0.8307996777334115 1.0 0.9785331503939556 6 Q13510,O75845 2 +Tube feeding 0.2476637216739601 0.2123220906155662 0.8318557624752945 1.0 0.9794226742169838 72 P61978,Q96J02,O75648,P07602,P37268,Q7L7X3,P55011,Q86YH6,P36776,O60762,P35637,Q9NZJ7,Q9H490,Q9UHX1,Q99720,Q96N66,P30153,Q9NZ01 18 +Multiple lipomas 0.407304180171706 0.2117308841635613 0.8323169922293516 1.0 0.9796472954237584 5 Q8TAA9,P53680 2 +Aplasia hypoplasia of the radius 0.3026019231868915 0.2094182269223488 0.8341217651839723 1.0 0.9803574599575314 20 Q96AY3,O15360,Q13535,Q15427,P98175 5 +Abnormal electroretinogram 0.2737282022768566 0.2089518830354955 0.8344858011831799 1.0 0.9803574599575314 32 P12235,O14773,P50897 3 +Upgaze palsy 0.4113843302347404 0.2070734006437065 0.835952535079411 1.0 0.9812256641178132 4 Q96RL7,Q96RR1 2 +Abnormality of hair pigmentation 0.2895116525399518 0.2057629790192246 0.8369760608252301 1.0 0.9813071182034542 26 P37268,Q6PGP7,Q9UBM7,Q13315,Q13126 5 +Cerebellar malformation 0.2493419386061442 0.2055261688821009 0.8371610546621566 1.0 0.9813071182034542 70 P23786,Q8TAA9,O43683,P16435,Q99567,Q9Y487,O75845,Q8NAT1,Q9Y4P3,P07437,Q15043 11 +Broad nasal tip 0.252445040116576 0.2054018677689596 0.8372581611189178 1.0 0.9813071182034542 53 Q7LGA3,O43292,P61978,P16278,Q9Y487,Q6DKJ4,Q9UHX1 7 +Dry hair 0.3697111175955738 0.2050201602096726 0.8375563740082639 1.0 0.9814090576651688 3 Q9Y276,P46778 2 +Cerebellar hypoplasia 0.2387650350924281 0.2045118884033829 0.8379535027167688 1.0 0.9816268213873192 136 Q8TD16,P11177,Q8WVX9,Q9UM00,Q9UBN7,Q15907,P98175,P23786,Q96KP1,O43683,Q12768,Q10713,Q99567,Q9UPT5,Q9Y487,P07437,Q9NVI7,Q8N201,Q6NUK1,O43292,P55795,P00374,Q9NXE4,Q13535,Q16625,O14936,Q8NFH4,Q9UBM7,Q8NAT1,Q5XKP0,Q9H490 31 +Laryngeal stenosis 0.4095707815196429 0.2022034687918008 0.8397576614391418 1.0 0.9821665050521176 4 Q96HY6 1 +Severe postnatal growth retardation 0.3424154706076023 0.2017586610586673 0.8401054005762194 1.0 0.9821665050521176 12 O96028,O76024,O95202 3 +Epidermal acanthosis 0.3511554830317547 0.1996961031278373 0.8417182616442616 1.0 0.9838045392702488 10 Q06136 1 +Congenital onset 0.2397945547154032 0.1984422518465178 0.8426990624968433 1.0 0.9841182203428774 115 Q7LGA3,Q8TD16,O14678,O95630,P78318,P51571,Q96KP1,P07602,Q99567,P46977,Q9NWS8,P07437,Q96N66,Q6NUK1,P55011,P61586,Q9NZJ7,Q96PU5,P08670,P12235,Q9BW92,Q9Y2Z2,Q8NFH4,Q8TCJ2,Q5XKP0,Q4J6C6,Q9UHX1,Q9Y3A4 28 +Abnormal posterior segment imaging 0.4070013417657923 0.1953916974588896 0.8450863158196147 1.0 0.9847682526455804 4 P04439 1 +Abnormality of thalamus morphology 0.3073426405635187 0.1928788216808427 0.8470538714395703 1.0 0.986071733076483 18 O75306,Q96KP1,Q96EY7,P11166,Q99496,Q9H9S5,Q9UPT5,P49792,O43819,Q96RR1 10 +Spastic tetraparesis 0.2874167131961576 0.19237888871097 0.8474454279030901 1.0 0.9862804253601596 26 Q9H9P8,P17900,P07602,Q5JPH6,O95630,Q9NZJ7,Q8WVX9 7 +Lens subluxation 0.3638751094251689 0.1884932312565265 0.8504900210935571 1.0 0.9886051265188393 3 Q99496,O75533 2 +Impaired pain sensation 0.2999410416044042 0.188471798257933 0.8505068210709859 1.0 0.9886051265188393 19 O15269,P61978,O15270,Q9NR77,O95831 5 +Neuronal loss in basal ganglia 0.3986112773356454 0.1875502225419059 0.8512292503149781 1.0 0.9890235287530174 5 O75306 1 +Abnormal circulating amino acid concentration 0.2511444151744363 0.1871396481157938 0.8515511425438693 1.0 0.9890235287530174 55 Q99797,Q9Y2Z2,O14678,Q9NP80,P03886,Q9Y619,P05067,P14854,P23378,Q99707,Q96EY8,Q9P0J0 12 +Protruding ear 0.2494291229056634 0.1869367269541158 0.8517102427993917 1.0 0.9890235287530174 50 Q06136,P61978,Q9H9S5,Q9H2P0,Q06787,P27635,Q9NXE4,Q9UL01,Q8NAT1,Q9Y4P3,P51812,O43505,Q9UIG0,P54886,Q8N201 15 +Abnormal renal insterstitial morphology 0.3287913234869064 0.186926473623506 0.8517182820793849 1.0 0.9890235287530174 14 P23786,Q86YH6,Q04446,Q9Y4P3,P09001 5 +Abnormal corpus callosum morphology 0.2242306316244003 0.1852118430800897 0.8530628803623739 1.0 0.9893485127717396 312 Q7LGA3,Q8TD16,P51970,P61978,P11177,Q5JPH6,O95630,Q9NZ01,P78318,Q9UBX3,Q8WVX9,P51571,Q13045,Q9UM00,O95202,Q15392,Q5SRE5,P98175,P00403,P04062,Q86XL3,P49902,P23786,O95831,Q15022,Q10713,O43683,P07602,P37268,P53701,Q9H9P8,Q96KP1,Q9UPT5,P78527,Q9NWS8,P42695,Q96EK5,P07437,Q96N66,Q9NVI7,Q96D71,Q6NUK1,P42858,P51572,O75648,P55011,P03886,Q9NZJ7,Q96PU5,O96028,P23378,Q9BW92,P42345,Q00839,P48651,Q6ZXV5,O14936,O75503,Q9Y366,Q9UBM7,Q96PZ0,Q8NAT1,Q13885,Q9UHX1,Q03154,P51812,Q96A33,Q9H490,O60313,Q9Y320,Q14738 71 +Anterior pituitary dysgenesis 0.3624161073825596 0.1844630832496111 0.8536501854700858 1.0 0.9897394893012258 3 P42898,Q15233 2 +Spastic dysarthria 0.3505831670851999 0.1835666197862236 0.854353451625564 1.0 0.9901038005119408 9 Q8N0X7,Q96GW9,P54886,Q8WVX9 4 +Hypochromic anemia 0.3421430294097374 0.1822952119569931 0.8553510560353077 1.0 0.9904114686761 11 O75027,P28288,P49327,O76031 4 +Abnormal uvula morphology 0.2472238124341684 0.1815982952310018 0.8558979868132892 1.0 0.9904114686761 47 P61978,P48651,O15360,Q9Y619,Q8NAT1,Q6DKJ4,Q15392 7 +Small nail 0.2465066080073988 0.1810169014159232 0.8563543097535655 1.0 0.9906927597398072 46 Q6NUK1,P23786,Q15022,Q12768,P48651,O95630,Q14738,Q9Y4P3,Q14739 9 +Poikiloderma 0.395961920913302 0.1804298357623246 0.8568151331239404 1.0 0.9909791158809628 5 P18074,O75431 2 +Hepatitis 0.2981081479021182 0.1789139440696185 0.8580052736657944 1.0 0.9914675961556852 19 Q9Y619 1 +Talipes calcaneovalgus 0.3892470208387594 0.1780321284599437 0.8586977439169203 1.0 0.991618997680211 6 Q9NR77,Q9UBM7 2 +Pituitary growth hormone cell adenoma 0.4000712893592607 0.1775407580744838 0.8590836533916482 1.0 0.9916279884863596 4 Q14697,Q9UBS4 2 +Somatic mutation 0.2483970877385632 0.176940547455584 0.8595550888153594 1.0 0.9916793997109908 50 P42345,O75874,O14965,P61586,P30154,Q13315,Q01844,Q92733,Q92804 9 +Facial erythema 0.3592063028888299 0.1757415217817194 0.8604970132718945 1.0 0.9920270778315688 3 Q9H1A4,P40818 2 +Atrophy degeneration involving the corticospinal tracts 0.340184025161811 0.1750234092134485 0.8610612395983293 1.0 0.9921851486046224 11 P35637,Q9Y4P3 2 +Missing ribs 0.3150304918440622 0.172632903133388 0.8629399872178185 1.0 0.9925346612712826 16 Q8TAA9,Q12768,Q96L58,Q13535,Q14739 5 +Syncope 0.3149004066185669 0.1720461619134353 0.8634012380718707 1.0 0.9925346612712826 16 Q9HD47,Q99959,O43572 3 +Abnormal circulating sulfur amino acid concentration 0.3434395678221592 0.1718420586535428 0.8635616992927415 1.0 0.9925346612712826 10 Q6PGP7,Q99707,O14678 3 +Talipes valgus 0.3975481611208474 0.1712328247758211 0.8640406981994895 1.0 0.9925346612712826 4 O00754,Q15233,Q9H2M9 3 +Difficulty standing 0.3923043488393078 0.1707945890828454 0.864385283846846 1.0 0.9925346612712826 5 O43292 1 +Hypoglycemic coma 0.3499618119156902 0.170272635848397 0.8647957304219585 1.0 0.9925346612712826 8 Q13423,Q16134,Q16836 3 +Abnormality of adrenal physiology 0.2673592543175428 0.1695539130163539 0.8653609697090925 1.0 0.9925346612712826 33 Q13423,O95470 2 +Abnormal circulating fatty acid concentration 0.2951865670226617 0.1694743180022647 0.8654235714184171 1.0 0.9925346612712826 20 Q9H845,P23786,O75648,O43772,P40855,Q16836,O75880,P40939,O75431 9 +Prenatal movement abnormality 0.2510864122010967 0.1679623829679588 0.8666128726377806 1.0 0.9929182259618076 61 Q70HW3,O75844,Q99567,P04062 4 +Dysphasia 0.3080170847500781 0.1664883551352699 0.8677726465389535 1.0 0.993512004884174 17 P53701 1 +Abnormal aortic morphology 0.2374979082717704 0.164511059813145 0.8693288408931916 1.0 0.9941342875645908 115 Q7LGA3,P61978,O14678,O15460,Q6DKJ4,P21964,P04062,O75844,O43683,P53701,Q9NWM8,Q9Y4P3,Q6NUK1,P42858,O75648,Q06787,O15360,Q96L58,Q96PU5,Q6ZXV5,P01889,Q96PZ0,Q9UHX1,Q96MF7 24 +Congenital malformation of the right heart 0.3413049902234562 0.1643935979952153 0.8694213030725901 1.0 0.9941342875645908 10 P01889,Q12768,O15460 3 +Abnormal circulating follicle stimulating hormone concentration 0.3664617780817559 0.1635919567956374 0.8700523769474078 1.0 0.9943346099743484 7 P16435,Q99496,Q96MF7,Q8IY37,P51809 5 +Atrioventricular canal defect 0.3369119569205734 0.1630975164724107 0.870441655183839 1.0 0.9943346099743484 11 Q9UBM7,P36776,Q12768,Q9UHX1 4 +Aplasia hypoplasia of the pubic bone 0.394153886042433 0.162910186190618 0.8705891505544925 1.0 0.9943346099743484 4 O96028 1 +Sarcoma 0.2505604130233064 0.1624632792418497 0.8709410429933213 1.0 0.9943346099743484 61 O75874,P48735,Q13126,Q15392,Q92804 5 +Incomprehensible speech 0.3536620951269451 0.1611507762876229 0.8719746491252895 1.0 0.994726261650709 3 Q9UPW6,Q6P1N0 2 +Cholecystitis 0.3438357861888662 0.1607898913100345 0.8722588872072725 1.0 0.994726261650709 9 Q9NZJ7,P07602 2 +Abnormal blistering of the skin 0.2889063806781152 0.1603299425930614 0.8726211731850224 1.0 0.9948952075135248 23 Q06136,Q9NZ08,P51798,P01889 4 +Abnormality of globe location 0.2254238363288293 0.1595275017904524 0.8732532924641809 1.0 0.9951274949199372 301 Q7LGA3,P61978,O14678,O95630,Q8WVX9,Q13045,Q9Y4W2,Q9Y2R0,Q9UM00,P51571,O95202,Q6DKJ4,P98175,P61313,P21964,P04062,O95831,O75844,Q32P28,Q15022,Q96KP1,Q12768,Q96J02,Q99567,P16278,Q9Y487,P78527,P07437,Q9NVI7,Q8N201,Q15043,Q6NUK1,Q15067,O43292,P42858,P55011,P55795,O75648,Q06787,O15360,Q9NXE4,Q9UL01,Q96L58,O96028,O75718,Q14739,P42345,Q00839,P16435,O60762,O14936,P48651,Q9Y366,Q6PGP7,Q9UBM7,Q15904,Q9BT22,Q96PZ0,Q9UHX1,Q03154,P51812,Q96A33,Q9H490,O60568,Q14738 65 +Gastrostomy tube feeding in infancy 0.2646680786400054 0.1582576191843338 0.8742538022131006 1.0 0.9955350894808984 34 Q96J02,Q7L7X3,P37268,Q86YH6,O60762,P36776,P35637,Q99720,Q9H490,P30153 10 +Abnormality of skeletal maturation 0.2361109835049426 0.1578299904689488 0.8745907658592085 1.0 0.9956747606424609 99 P16435,P48651,Q06787,Q9Y619,Q99519,Q13535,P13073,O96028,O95202,Q9Y4P3,Q15800,Q14108,P04062 13 +Hypothermia 0.3352879292006777 0.1572817942347836 0.8750227677737001 1.0 0.9956786135382344 11 O43772,P03886 2 +Abnormal shape of the palpebral fissure 0.3163092038405162 0.1552409353555057 0.8766313777052295 1.0 0.9965327577241244 15 P55795,Q9UHX1 2 +Myositis 0.3343776997605547 0.1540525351279774 0.8775683129011438 1.0 0.9971099001562028 11 Q9NZ08,P22626 2 +Hypopigmented macule 0.3899591360186872 0.1528858185256964 0.8784883196058162 1.0 0.9971602658816608 4 Q15149,Q15233,Q9H488 3 +Abnormal renal vascular morphology 0.3899591360186868 0.1528858185256956 0.8784883196058169 1.0 0.9971602658816608 4 P42224,P21912,O60333 3 +Abnormality of carpal bone ossification 0.3798107141443891 0.1525628462778212 0.8787430263044917 1.0 0.9971602658816608 6 Q96L58,P36776 2 +Single transverse palmar crease 0.2457483411960571 0.1516509429142966 0.8794622514050612 1.0 0.997498227724878 50 Q96J02,P36776,Q9H2P0,P40855,Q9NXE4,P27635,P51812,Q13535,P62266,O96028,O95202,Q6DKJ4,Q15907,Q5SRE5,Q9UHX1,P98175 16 +Drowsiness 0.3793808411215081 0.1514412040667903 0.8796276881164067 1.0 0.997498227724878 6 P08559,O00754,P36776,Q12756,Q9UJS0 5 +Aplasia cutis congenita of scalp 0.3783545336613707 0.1487770782927487 0.8817295381918555 1.0 0.9982062365360852 6 O96028 1 +Aplasia hypoplasia involving bones of the lower limbs 0.2349903866490332 0.1472891180453855 0.8829038213445672 1.0 0.9982062365360852 97 Q7LGA3,Q9Y4W2,O95202,O95831,Q9Y619,Q15427,P42858,O75648,P55011,Q06787,Q96L58,Q13535,P13073,O96028,Q96AY3,Q9Y366,Q9UBM7,Q96PZ0,Q9UHX1,Q96HY6,Q96A33,Q13510 22 +Postaxial polydactyly 0.2846097889965104 0.1470480475631154 0.8830940960217157 1.0 0.9982062365360852 24 P61978,Q10713,Q9Y366,Q9UBM7,Q9UM00,O75845,O43909,P98175,P30153,Q14739 10 +Hammertoe 0.2917703865950983 0.1468378939242626 0.8832599738269147 1.0 0.9982062365360852 19 Q99720 1 +Sudden death 0.2665984945208489 0.1454520386970034 0.8843539805343872 1.0 0.9988252364940556 31 O43572,O15460,P50402,P01889,Q9Y4P3 5 +Type ii diabetes mellitus 0.251937283509726 0.1448892099401777 0.8847983457576776 1.0 0.9988252364940556 40 O76024,P03886,Q13315,Q9Y4P3,P00403 5 +Preaxial polydactyly 0.3183978520123373 0.1442845433027212 0.8852757832492706 1.0 0.9988252364940556 14 O96028,Q9UHX1 2 +High narrow palate 0.2613768231870168 0.1432350432059613 0.8861045546754605 1.0 0.9990385906678718 35 Q6NUK1,P23786,P61978,Q12768,P16435,P48651,Q9Y619 7 +Conical tooth 0.3413014517140973 0.1431815509980988 0.8861467998584374 1.0 0.9990385906678718 8 Q9Y487 1 +Dermatological manifestations of systemic disorders 0.2393710279796196 0.142134328233199 0.8869739034192854 1.0 0.9991167553948456 74 P61916,P36551,Q16134,P98175,O75844,P11166,P28288,O75648,Q6NUQ1,P00374,Q00325,O43772,Q16625,Q14739,Q6PGP7,Q14376,O14936,Q5HYI8,Q15904,O15118,P51812 21 +Sleep wake cycle disturbance 0.3807299270073043 0.1418204573457292 0.8872218247716352 1.0 0.9991167553948456 5 Q9Y4R8,Q05086,Q8N3U4,Q9UBM7 4 +Albuminuria 0.3789781021897862 0.1376390495717507 0.8905256921295412 1.0 1.0 5 Q14697,Q9UBS4,Q5JRA6,O00330 4 +Spinal muscular atrophy 0.3294853004813652 0.1370731683838075 0.8909729607813339 1.0 1.0 11 Q13510,Q99720,Q16637 3 +Polyphagia 0.3328161146083228 0.1359096324488115 0.8918927205439253 1.0 1.0 10 Q4J6C6 1 +High myopia 0.3342013302093858 0.1301768204574741 0.8964265331092907 1.0 1.0 9 Q9Y487 1 +Sepsis 0.2999693394289866 0.1300932570724889 0.8964926448616963 1.0 1.0 17 P01889,P42892 2 +Abnormal anterior horn cell morphology 0.3708556657429811 0.1299043693426371 0.8966420873487433 1.0 1.0 6 Q13510 1 +T cell lymphoma 0.3756501948755152 0.1298452325191865 0.8966888754402644 1.0 1.0 5 P49327,Q07864 2 +Decreased activity of the pyruvate dehydrogenase complex 0.2847733114851134 0.1289386855220348 0.8974061655304739 1.0 1.0 22 O75306,Q9P0J0,Q96CU9,P11177 4 +Weak cry 0.3334918085388672 0.1280131877700613 0.898138536578784 1.0 1.0 9 Q13510 1 +External genital hypoplasia 0.2334245082335156 0.1257747017956815 0.8999102677622954 1.0 1.0 133 Q6DKJ4,O75844,Q15022,Q10713,Q12768,P53701,Q9Y619,P78527,P46977,Q9Y4P3,P07437,Q9NVI7,Q6NUK1,P42892,Q06787,O75845,P51114,O95470,Q6P2Q9,P16435,O60762,O14936,P48651,P27635,Q9UBM7,Q8TCJ2,Q9UNW1,Q8NAT1,P48449,O43505 30 +Lower limb hyperreflexia 0.2862269535648222 0.1240504815405016 0.9012753052201924 1.0 1.0 20 O60762,Q15041,Q8WVX9,P13073,P21912,Q14739 6 +Unusual infection 0.2303986352639858 0.1237636610263682 0.9015024048449194 1.0 1.0 220 P51798,O15460,Q13315,Q13423,O95202,Q6DKJ4,Q9H0U3,P08236,P04062,P07602,P16278,Q13277,Q9Y487,Q9UJW0,Q9Y4P3,P10253,Q9NZ08,P09601,Q9NPL8,Q06787,O15360,P15586,Q9NZJ7,O96028,Q03519,P54802,Q03518,Q14739,Q8TAA9,O76024,Q6PGP7,Q15904,Q9BT22,P01889,Q96A33,Q13510,Q8N5M9 37 +Renal insufficiency 0.2318157495891914 0.1232790802361566 0.9018861060125428 1.0 1.0 91 P23786,Q8TAA9,Q10713,P52429,Q12769,O15360,O15460,P01889,P06280,Q9NWS8,O95470,Q9NZ08,Q16625,Q14108,Q9Y4P3 15 +Hip subluxation 0.3336399190453561 0.120693527438076 0.903933785873934 1.0 1.0 8 Q96L58 1 +Abnormality of the common coagulation pathway 0.3157273533039297 0.1184022237078648 0.9057489639102176 1.0 1.0 13 P38435 1 +Aplasia hypoplasia involving forearm bones 0.2809030058987809 0.1167550405065776 0.9070541724737956 1.0 1.0 23 Q13535,P98175,Q96AY3,Q15427 4 +Nyctalopia 0.26668115688548 0.1157333487530811 0.9078638753511296 1.0 1.0 29 Q10713,P38435,P40855,Q6P4Q7,Q9Y287,Q6P2Q9 6 +Abnormal renal pelvis morphology 0.2449113641592403 0.1137789351066025 0.9094130374875298 1.0 1.0 58 P23786,P61978,O76024,P16435,Q9UL01,Q6DKJ4,O75718,P98175 8 +Abnormality of the pulmonary vasculature 0.239047503980765 0.1130811398947409 0.9099662272577392 1.0 1.0 46 Q7LGA3,P42858,O75648,Q6PGP7,P51798,Q96PZ0,Q15392,Q9Y4P3,O75718 9 +Spinal cord compression 0.3635896726704703 0.1126249277825956 0.910327921273747 1.0 1.0 6 Q96L58,Q9UNW1 2 +Decreased circulating progesterone 0.3634442503028067 0.1122893082091456 0.9105940190011788 1.0 1.0 6 P16435 1 +Abnormal circulating progesterone level 0.3634442503028067 0.1122893082091456 0.9105940190011788 1.0 1.0 6 P16435 1 +Abnormal dentin morphology 0.3630016242193304 0.1112702498315703 0.9114020460755068 1.0 1.0 6 Q96L58 1 +Abnormality of primary teeth 0.3006196541428534 0.111057448005078 0.9115707915118356 1.0 1.0 16 O75844,P61978,P51798,P61586,Q13045 5 +Abnormality of periauricular region 0.2778237941691305 0.1095813935497353 0.912741367575494 1.0 1.0 24 P61978,Q12768,O96028,O95202,Q15427 5 +Abnormal blood sodium concentration 0.3243624695320438 0.1093990008528723 0.9128860261969824 1.0 1.0 10 P36551,Q13423 2 +Renal agenesis 0.243099178148433 0.1082340545737365 0.9138100319757818 1.0 1.0 55 Q7LGA3,O75306,P42695,P16435,O15360,Q15427,Q15392,Q9UHX1,Q86XL3 9 +Abnormality of the peritoneum 0.2817700959947261 0.1073032388213347 0.914548415171963 1.0 1.0 21 Q92621,Q12769,Q8NFH4,Q5HYI8,O43707,Q01844,Q8N1F7 7 +Abnormal carotid artery morphology 0.2945582362012778 0.1069293750587592 0.914845008860427 1.0 1.0 17 O75844,Q9Y4P3 2 +Keratoconjunctivitis 0.3202810653923523 0.1068928637252415 0.9148739746763463 1.0 1.0 11 Q9NZ08,Q14739 2 +Broad columella 0.3683596030356155 0.1059276437967764 0.9156397608762936 1.0 1.0 4 Q8TC12,Q13868,O00443 3 +Abnormal circulating fatty acid anion concentration 0.303768097490922 0.1050814454933407 0.91631118213463 1.0 1.0 15 O43772,P23786,O75648 3 +Abnormal salivary gland morphology 0.3641315292670937 0.1043953647392444 0.916855600986748 1.0 1.0 5 P52701,P16615 2 +Abnormality of the female genitalia 0.2330570780324318 0.102911174202351 0.9180334690602896 1.0 1.0 143 O75874,O14965,P48735,Q13315,O95202,Q6DKJ4,Q15392,Q01844,P21964,O75844,O43683,P53701,Q9Y619,P49770,Q15427,Q9Y4P3,Q06787,O15360,Q13535,O96028,P16435,Q5HYI8 22 +Neurogenic bladder 0.3242424864963862 0.1009726158725206 0.9195721984208128 1.0 1.0 9 Q8TAA9,O76024 2 +Cortical dysplasia 0.2612197500211887 0.1008912438543667 0.9196367940324026 1.0 1.0 30 P42345,P55011,Q96PU5,Q13885,P07437,Q96N66 6 +Keratitis 0.3146233710500313 0.1004448417971061 0.9199911711433664 1.0 1.0 12 Q9NZ08,Q14739 2 +Intestinal polyp 0.2874417504772096 0.0994403022385683 0.9207886847624068 1.0 1.0 18 P42345,O43683,P42892,P52701,Q07864,P21912 6 +Broad toe 0.2609546385503122 0.0991944354571092 0.9209838929319843 1.0 1.0 30 Q7LGA3,P42858,O75648,P61586,Q96PZ0,Q15427,Q9UHX1 7 +Hypoplastic iliac wing 0.325988536709384 0.0975323663576605 0.9223036321113676 1.0 1.0 3 Q9UBN7 1 +Tracheal stenosis 0.3560247374246017 0.0957012474592283 0.9237578501202184 1.0 1.0 6 Q96HY6,Q9UBM7,O43909 3 +Retinal arteriolar tortuosity 0.3197016336385807 0.0955941797479817 0.9238428879194114 1.0 1.0 10 P21964 1 +Central adrenal insufficiency 0.3594160583941659 0.0946651710330376 0.9245807831893772 1.0 1.0 5 Q9NRG9,Q9NW13,Q9NSE4,P35222 4 +Delayed ability to walk 0.2373553733144453 0.0937248320400522 0.9253277439860804 1.0 1.0 72 P61978,Q10713,O75648,P82663,P55011,Q6ZXV5,O14936,P35637,P27635,Q8WVX9,Q96PZ0,Q15907,Q14738,Q99720,Q96N66,P21912,Q96D71 17 +Abnormally folded helix 0.2803785485568612 0.0931864597261408 0.9257554311533 1.0 1.0 19 P23786 1 +Aplasia hypoplasia involving bones of the upper limbs 0.232558670427519 0.0917485906064427 0.926897790447328 1.0 1.0 153 P38435,O95630,P51798,Q9Y4W2,Q9UBN7,O95202,Q6DKJ4,P98175,O95831,O75844,Q32P28,Q9Y619,O15228,Q15427,Q6NUK1,P42858,Q06787,O15360,Q96L58,Q13535,P13073,O96028,Q14739,P42345,Q96AY3,P16435,O60762,O14936,P48651,Q9Y366,Q9UBM7,Q9UHX1,P51812,Q13510 34 +Supernumerary spleens 0.306842667744596 0.0878654917287742 0.9299835841013152 1.0 1.0 13 Q15904,O96028,O95202 3 +Hyperventilation 0.337289277006709 0.0873738425117463 0.9303743604988196 1.0 1.0 7 P03886,O14936 2 +Arnold chiari malformation 0.2697138958041691 0.0872978632654791 0.9304347524054076 1.0 1.0 26 P16435,Q15043,O75845,Q9Y4P3 4 +Bifid uvula 0.2469111496359913 0.0871862614028567 0.9305234595823066 1.0 1.0 39 P61978,P48651,Q6PGP7,Q9Y619,Q9NXE4,Q8NAT1,Q15392 7 +Pseudoepiphyses 0.3361211365451548 0.0847016564541908 0.9324985790421664 1.0 1.0 7 O96028,O95202 2 +Ectopic kidney 0.2837436228568448 0.0837518672958049 0.9332537178303376 1.0 1.0 18 O15360,Q9UHX1,Q9Y4P3 3 +Misalignment of incisors 0.3538686131386906 0.0837322596125059 0.9332693077382346 1.0 1.0 5 Q96N67,Q99496,Q8WVM7,Q9BSJ2 4 +Acne 0.2978442983730319 0.0832179430416141 0.9336782457412504 1.0 1.0 15 Q9NZ08,P21964 2 +Neoplasm of fatty tissue 0.3192650134987363 0.0823554107019731 0.9343640926536634 1.0 1.0 8 P21912,Q8TAA9,P27635 3 +External ear malformation 0.2884138796023988 0.0819525287083175 0.9346844630140064 1.0 1.0 17 P07437,Q9UL01 2 +Abnormality of the musculature of the upper limbs 0.2317532425486014 0.0818828439094917 0.9347398771981884 1.0 1.0 76 Q15120,P07602,Q8TB36,P31483,Q9Y487,Q9NZJ7,O14979,O60568,P12235,Q9NR77,O60313,Q9BQT8 12 +Recurrent gastroenteritis 0.3168952436533505 0.0800232423697785 0.9362187705094918 1.0 1.0 3 O00754,Q96AX1 2 +Widely spaced incisors 0.3537653239930011 0.0786813153228292 0.9372861076109916 1.0 1.0 4 Q99496,Q8WVM7,Q9BSJ2 3 +Male reproductive system neoplasm 0.2965430947390712 0.0785774605611072 0.9373687159603944 1.0 1.0 15 Q13423 1 +Feeding difficulties 0.2186335059355844 0.0774894431697017 0.938234189152766 1.0 1.0 369 Q7LGA3,P61978,O14678,Q96CU9,P53985,P51571,Q13045,O43676,Q15907,Q15392,Q99707,Q99720,P21964,Q9UGP8,P04062,Q2TAA5,O95831,P23786,Q99797,O75306,Q10713,Q15022,P07602,P37268,P53701,Q86Y39,Q12768,P16278,Q13277,Q9Y619,Q9Y487,P46977,O43681,Q9NWS8,P10253,Q96EY8,Q96N66,Q9NVI7,Q6NUK1,P42858,Q9Y6M9,Q9NPL8,P55795,O75648,P55011,P03886,P00374,Q9NZJ7,P42345,Q9Y2Z2,O76024,O96000,O60762,O14936,Q9H490,P35637,Q9UBM7,P14854,Q96PZ0,Q8TCJ2,Q4J6C6,Q5XKP0,Q9UHX1,Q9Y584,P51812,Q96A33,Q13510,Q16836,O60313,Q9NZ01 70 +Abnormality of the chin 0.2278196444499566 0.0759556160086857 0.9394544094343736 1.0 1.0 90 O75844,Q6NUK1,Q7LGA3,Q15022,P55011,Q96J02,P42345,P48651,P16278,Q06787,Q9NXE4,Q13045,P78527,Q9NVI7,Q9UHX1,Q9Y4P3,P51812,Q9H490 18 +Lymphedema 0.2856376764489688 0.0711411378914459 0.9432854277914022 1.0 1.0 17 P06280,Q14739 2 +Neonatal hypotonia 0.2398223053712451 0.0689673977840165 0.9450155704850256 1.0 1.0 57 P23786,Q2TAA5,P51114,Q9Y584,Q14738,Q15067 6 +Albinism 0.3104756346659021 0.0686680862694752 0.945253821687235 1.0 1.0 3 O00203,Q9UPZ3 2 +Gastroparesis 0.3286769265785031 0.0683693105002379 0.9454916513212844 1.0 1.0 7 P12235 1 +Cerebral visual impairment 0.2386905584634361 0.0669215601375069 0.9466441490044688 1.0 1.0 68 P37268,P03886,Q96CU9,P14854,P12235,Q96N66,P00403 7 +Oromotor apraxia 0.3445255474452608 0.0665733257554765 0.9469213815854468 1.0 1.0 5 Q9BVA1,Q8N3U4,Q14683,P42356 4 +Cerebellar vermis atrophy 0.2965970477073542 0.0657951327946815 0.9475409313085584 1.0 1.0 14 P42858,Q10713,P07437 3 +Choreoathetosis 0.2527856053948546 0.0632530818092599 0.9495649761960374 1.0 1.0 32 P04350,Q96RL7,O14936,Q13315,Q5XKP0,Q9P0J0 6 +Bloody diarrhea 0.3417851961670508 0.0618377549131756 0.9506920369326756 1.0 1.0 5 Q6PGP7 1 +Abnormality of the choanae 0.2432355314248628 0.0600220908012415 0.9521380404923012 1.0 1.0 39 O75844,P55011,P16435,P48651,P78318,O15360,Q9UBM7,P21964 8 +Melanocytic nevus 0.3010673180718984 0.0591220260663249 0.952854915061593 1.0 1.0 12 P04049,Q15022,P21912,Q96AY3 4 +3 methylglutaconic aciduria 0.3094340720834149 0.0590810584962322 0.952887545414681 1.0 1.0 8 Q53H12,Q5XKP0,Q9NVI7 3 +Convex nasal ridge 0.2677337310006805 0.0579149334614514 0.9538163879062518 1.0 1.0 24 O75844,Q6NUK1,Q13535,O96028,O95202,Q5SRE5 6 +Abnormal conus terminalis morphology 0.3232851676525651 0.0572916410097797 0.9543128789255728 1.0 1.0 7 O96028 1 +Abnormal cerebral cortex morphology 0.2280376358746398 0.0557977011653213 0.9555029662971136 1.0 1.0 244 Q7LGA3,P51970,P11177,Q16134,Q15392,P00403,P04062,Q86XL3,O75306,P23786,Q15022,Q10713,P37268,Q9Y619,Q9Y487,Q9UPT5,Q9NWS8,Q15427,Q9Y4P3,P07437,P42695,Q96N66,P42858,O75648,P55011,P03886,Q06787,P05067,Q9NXE4,Q13535,Q96PU5,Q16625,P42345,O76024,Q96RL7,O60762,O14936,Q6ZXV5,O75503,P35637,Q9UBM7,Q96PZ0,Q8NAT1,Q13885,P51812,Q9Y320,Q9NZ01 47 +Burkitt lymphoma 0.2666277712952096 0.0553877809997156 0.9558295302444596 1.0 1.0 2 P49327 1 +Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells 0.2666277712952096 0.0553877809997156 0.9558295302444596 1.0 1.0 2 P49327 1 +Increased b cell count 0.2666277712952096 0.0553877809997156 0.9558295302444596 1.0 1.0 2 P49327 1 +Abnormal proportion of double negative alpha beta regulatory t cell 0.2666277712952096 0.0553877809997156 0.9558295302444596 1.0 1.0 2 P49327 1 +Coombs positive hemolytic anemia 0.2666277712952096 0.0553877809997156 0.9558295302444596 1.0 1.0 2 P49327 1 +Follicular hyperplasia 0.2666277712952096 0.0553877809997156 0.9558295302444596 1.0 1.0 2 P49327 1 +Abnormal distal phalanx morphology of finger 0.2365209392297099 0.0547250621788454 0.9563575025460967 1.0 1.0 53 Q7LGA3,O75844,Q6NUK1,P42345,P16435,P38435,O95630,Q9Y366,P51798,Q96L58,Q6DKJ4 11 +Aplasia hypoplasia of the uterus 0.2759207696536638 0.0524038480959612 0.9582069079949846 1.0 1.0 18 O96028,P53701 2 +Multifocal epileptiform discharges 0.2530125057807449 0.0503062869525862 0.9598783138515474 1.0 1.0 30 O75503,Q9UBX3 2 +Oral ulcer 0.3030144605806257 0.0472601701556458 0.962305872201786 1.0 1.0 9 Q9NZ08 1 +Intellectual disability borderline 0.3327495621716342 0.0457572355271558 0.9635037441901476 1.0 1.0 4 Q9UDR5,O75962,Q7Z392 3 +Absent hypoplastic paranasal sinuses 0.2944266121972655 0.0438411029335094 0.965031063162116 1.0 1.0 3 P10644,P04066 2 +Abnormal circulating proline concentration 0.2937660107676584 0.042925557940331 0.9657608752336452 1.0 1.0 3 O96000 1 +Tinnitus 0.2820672491448345 0.0426114381372009 0.9660112774581048 1.0 1.0 16 Q15043,Q9NR28,Q9NR77,P21912,O95831 5 +Impairment in personality functioning 0.2263785542413995 0.0403312032687131 0.9678290773986916 1.0 1.0 221 Q7LGA3,Q15165,Q96CU9,Q7KZN9,O15460,P16615,Q13045,P06280,P50897,P21964,P00403,Q9P0J0,P04062,O75306,P07602,P49770,O43681,Q9Y4P3,Q96N66,P42858,P17900,O75648,P55011,P55795,P03886,Q06787,P05067,Q9NZJ7,Q6DKK2,P12235,P23378,Q92804,Q8TAA9,O76024,Q96RL7,O75503,P35637,P01889,Q96PZ0 39 +Cerebellar dysplasia 0.3265186915888006 0.0401535574916818 0.9679707034967152 1.0 1.0 6 P63000,P42356,Q8NI27,Q9H9S5,Q7Z3E5 5 +Fetal onset 0.30048079982742 0.0399718452931344 0.9681155725487188 1.0 1.0 8 P27635,Q9ULH0 2 +Irregular hyperpigmentation 0.2301956049062888 0.039267879482979 0.968676815314698 1.0 1.0 74 Q7LGA3,Q06136,O75844,P42858,O43683,O75648,P42345,Q6PGP7,O15360,P16615,Q13315,Q96PZ0,P07437,Q14739 14 +11 pairs of ribs 0.2936086149121481 0.0387568832066789 0.969084221202829 1.0 1.0 12 Q96L58,Q14739 2 +Abnormal cortical gyration 0.2281831351040746 0.0370902838315409 0.9704130190786292 1.0 1.0 137 P11177,Q16134,Q15392,Q86XL3,P23786,Q15022,Q10713,P37268,Q9UPT5,Q9Y487,Q9NWS8,Q15427,P42695,P07437,Q96N66,P55011,Q9NXE4,Q13535,Q16625,P42345,O14936,Q6ZXV5,Q8NAT1,Q13885,Q9Y320,Q9NZ01 26 +Nephritis 0.2599860436225952 0.0362835507002372 0.9710562659430696 1.0 1.0 26 Q9UBS4,Q92621,Q12769,P52429,Q8NFH4,O43707,P49327,Q8N1F7 8 +Abnormal electrophysiology of sinoatrial node origin 0.2714808954547676 0.0357479121150522 0.9714833666022492 1.0 1.0 18 Q9HD47,Q99959,P21912,Q14BN4 4 +Arrhinencephaly 0.291243899733864 0.0326543910043595 0.9739501951821016 1.0 1.0 12 P21964,Q15427 2 +Limb myoclonus 0.3214301181588112 0.0322359426377297 0.9742838929846857 1.0 1.0 6 Q13510 1 +Atresia of the external auditory canal 0.2822494270077099 0.0315304891302893 0.9748464774176592 1.0 1.0 15 Q9Y619 1 +Abnormal ilium morphology 0.2605818614308191 0.0308977519325797 0.9753510827665814 1.0 1.0 25 Q99575,Q8TAA9,P36776,P16278,Q96L58,P01889,Q9UBN7,P51812,O95831 9 +Proximal muscle weakness in upper limbs 0.287495756465513 0.0299966149203168 0.9760697528595952 1.0 1.0 13 Q8WXH0,P36551,P50402,Q9BTV4,P50336,P50570 6 +Alopecia 0.2295073669060506 0.0265732236680673 0.9788001301331608 1.0 1.0 47 O75844,Q06136,P61586,O15460,Q13535,P01889 6 +Lymphocytosis 0.317605958781492 0.0257643506675398 0.97944529644983 1.0 1.0 5 P49327 1 +Gliosis 0.2318252076204595 0.0255256396832197 0.9796356976377932 1.0 1.0 42 O75306,P42858,Q10713,P35637,Q7KZN9,Q16134,P04062 7 +Recurrent fever 0.2823669064963319 0.0230596720559391 0.9816026741621642 1.0 1.0 14 Q13510,Q9NR77 2 +Bicornuate uterus 0.2914837302397209 0.0229940076610223 0.9816550528806882 1.0 1.0 9 O15360,Q15427 2 +Narrow nose 0.3041191936897388 0.022964530048989 0.9816785664032784 1.0 1.0 7 Q9Y4A5,Q9UPW6,Q07864,Q14683,P49589,O75431 6 +Sparse eyelashes 0.2627684730057111 0.0211721697715678 0.9831083146099872 1.0 1.0 19 O75844 1 +Abnormality of the antihelix 0.2814531120268045 0.0205503934303388 0.9836043124057934 1.0 1.0 14 Q5SRE5,P98175,P16435 3 +Abnormal dental pulp morphology 0.2881665908992821 0.0177290118143993 0.985855036201339 1.0 1.0 10 Q13045,Q9Y366,Q9P2L0 3 +Self mutilation 0.2802024212520908 0.0171620560546546 0.9863073326099544 1.0 1.0 14 Q10713,Q9UBM7,Q96RL7 3 +Death in adulthood 0.2800406731990527 0.0167277383821467 0.9866538182259104 1.0 1.0 14 P51812,P52701,P05067,Q9Y4P3 4 +Muscular dystrophy 0.2520296143960606 0.0165660517746634 0.9867828075996206 1.0 1.0 28 O43683,O14979,P50402,Q8NAT1,P22626 5 +Abnormality of central nervous system electrophysiology 0.2274776290322021 0.0138576825475729 0.9889435229203531 1.0 1.0 159 Q9BQE5,Q9UBX3,P50897,P21964,P00403,Q2TAA5,P07602,Q96N66,Q14108,Q15067,O43292,P03886,Q9NZJ7,Q99519,P13073,O96028,O75503,Q96A33,O60313 19 +Fibroadenoma of the breast 0.2667055733878134 0.0121577326854562 0.9902997717623676 1.0 1.0 3 P10644,P49327 2 +Neonatal onset 0.2588170600184034 0.0120686464319956 0.9903708470939498 1.0 1.0 23 Q8TB36,Q15904,Q13277,Q96EY8,Q9H490,P09001 6 +U shaped upper lip vermilion 0.2646023255780463 0.0102825975291022 0.991795818760659 1.0 1.0 3 O60762 1 +Sleep disturbance 0.2271559061555063 0.0087220622886452 0.993040889396634 1.0 1.0 159 Q7LGA3,P61978,P36551,Q13045,P50897,P04062,O95831,Q96KP1,P11166,Q99567,Q9Y4P3,Q96N66,Q9NVI7,P42858,O75648,P55011,Q06787,P15586,P51114,P54802,O76024,Q96RL7,O14936,O75503,Q9UBM7,Q96PZ0,Q9UHX1,P51812,Q96A33,P35610,Q9NZ01 31 +Abnormality of the intrinsic pathway 0.2826942295455578 0.0086173345301907 0.9931244469178502 1.0 1.0 11 P38435 1 +Displacement of the urethral meatus 0.2259618139719655 0.00825819472207 0.9934109888238976 1.0 1.0 123 O75844,P42345,P51970,P37268,P53701,P16435,P48651,Q9Y619,Q9UBX3,Q13535,P51571,O96028,Q9UHX1,P07437,P21964 15 +Gastritis 0.3022504770058417 0.0065822380838739 0.9947481717807032 1.0 1.0 6 Q6PGP7 1 +Hypogonadotropic hypogonadism 0.242780346333522 0.0065613872962263 0.9947648079429964 1.0 1.0 33 P00403 1 +Infantile spasms 0.2432602950710987 0.0059945969744819 0.9952170322719872 1.0 1.0 32 P03886,Q9UBX3 2 +Amaurosis fugax 0.2806065672005912 0.004520692889922 0.9963930212247732 1.0 1.0 8 P01889 1 +Abnormality of the thoracic cavity 0.2772148771775694 0.004142398179859 0.9966948539000172 1.0 1.0 13 P01889,O15460,Q01844 3 +Cone shaped epiphyses of the phalanges of the hand 0.2911551957874133 0.0040727687598228 0.9967504096705532 1.0 1.0 7 Q13535 1 +Abdominal wall muscle weakness 0.2945125510799838 0.0037194014162866 0.9970323538768946 1.0 1.0 4 P36507,P21359,P46976 3 +Aplasia hypoplasia of the phalanges of the hand 0.2334557409307051 0.0010110657403165 0.9991932863932892 1.0 1.0 60 O75844,Q6NUK1,P42345,P16435,P48651,P38435,O95630,Q9Y366,P51798,Q6DKJ4,Q9UHX1,Q14739 12 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8fba14132bc537a0846fdf51c79f6e0144b07d03 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 4th finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal endothelium morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal descemet membrane morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger flexion creases", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemidiaphragm morphology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lacrimal punctum morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal perifollicular morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the dental root", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent lacrimal punctum", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Acute rhabdomyolysis", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anemic pallor", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior chamber synechiae", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior synechiae of the anterior chamber", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lens", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of metacarpal bones", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the proximal phalanges of the hand", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar impression", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonate wasting renal tubular acidosis", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid nose", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central opacification of the cornea", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cephalohematoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical cord compression", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Choroideremia", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic myelogenous leukemia", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clinodactyly of the 3rd finger", "Clinodactyly of the 4th finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital finger flexion contractures", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital ptosis", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dacryocystitis", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased csf homovanillic acid", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to anti cd3", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased nasal nitric oxide", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatochalasis", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the 4th finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse white matter abnormalities", "Digenic inheritance", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Discoid lupus rash", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal symphalangism", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Dumbbell shaped long bone", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg myotonic discharges", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibroelastosis", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female pseudohermaphroditism", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal aware seizure", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Ganglioneuroblastoma", "Ganglioneuroma", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked horizontal nystagmus", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonadotropin deficiency", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemolytic uremic syndrome", "Hemoptysis", "Hemorrhage of the eye", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hypereosinophilia", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the primary teeth", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic iris stroma", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic spleen", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Immotile cilia", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired lymphocyte transformation with phytohemagglutinin", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired renal concentrating ability", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased fibular diameter", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intervertebral space", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urinary potassium", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Increased vldl cholesterol concentration", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Internally nucleated skeletal muscle fibers", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "Ivory epiphyses", "Ivory epiphyses of the phalanges of the hand", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Knee pain", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Linear arrays of macular hyperkeratoses in flexural areas", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Lobar holoprosencephaly", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lupus anticoagulant", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microangiopathic hemolytic anemia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Miosis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuroma", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non medullary thyroid carcinoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Oxycephaly", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary cystadenoma of the epididymis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid dysgenesis", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial absence of thumb", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Percussion myotonia", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior rib cupping", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged pr interval", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent thrombophlebitis", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal sodium wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocerebellar cyst", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of finger phalanx", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe platyspondyly", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sick sinus syndrome", "Sideroblastic anemia", "Silver gray hair", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skewfoot", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small forehead", "Small hand", "Small intestinal dysmotility", "Small nail", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous pneumothorax", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary cusp", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Thinning of descemet membrane", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic dysplasia", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thrombophlebitis", "Thymus hyperplasia", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of long finger extensor muscles", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABAT", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACY1", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AGTPBP1", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP10", "AKAP9", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG11", "ALG2", "AMPD2", "ANAPC1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANXA11", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APOL2", "APP", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6IP1", "ARMC9", "ARPC1B", "ARSA", "ARVCF", "ASAH1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG7", "ATIC", "ATL3", "ATM", "ATP1A1", "ATP2A2", "ATP2B4", "ATP5A1", "ATP6AP1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATR", "ATXN10", "AURKA", "B3GALT6", "B4GAT1", "BAG3", "BANF1", "BARD1", "BAX", "BAZ1B", "BCAP31", "BCAT2", "BCKDHB", "BCKDK", "BCR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BUB1", "BUB1B", "BUB3", "BUD23", "C19orf70", "C1QBP", "C21orf59", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CAPN1", "CARS", "CARS2", "CASK", "CAST", "CBFB", "CBL", "CC2D1A", "CCDC115", "CCDC22", "CCDC47", "CCT5", "CD109", "CD2AP", "CD3EAP", "CDC40", "CDC42", "CDC6", "CDC73", "CDH2", "CDK13", "CDK4", "CDK5", "CDK5RAP2", "CELF2", "CENPF", "CEP250", "CEP290", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK2", "CHM", "CHORDC1", "CHUK", "CISD2", "CIT", "CIZ1", "CLASP1", "CLCC1", "CLCN7", "CLIP1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT3", "CNP", "COA3", "COA7", "COASY", "COG5", "COG7", "COG8", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "COX6B1", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CREBBP", "CRKL", "CRTAP", "CSNK2A1", "CSNK2B", "CSTB", "CTBP1", "CTDP1", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CUL3", "CUL4B", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DAXX", "DBT", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DKC1", "DLAT", "DLD", "DLST", "DNAAF2", "DNAAF5", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DPP9", "DPYSL5", "DSC2", "DSE", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EHHADH", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "EMC1", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "ETHE1", "EWSR1", "EXOC2", "EXOC6B", "EXOC7", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXTL3", "EYA4", "EZR", "FAH", "FAM126A", "FAM50A", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FUCA1", "FUS", "FXR1", "FYCO1", "G6PD", "GAA", "GALE", "GALK1", "GALNT2", "GAMT", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GBA", "GBE1", "GCDH", "GCLC", "GDAP1", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GNAI2", "GNAI3", "GNB1", "GNE", "GNPAT", "GNS", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2E2", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HCFC1", "HDAC6", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS5", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IGF2R", "IKBKB", "INF2", "INPPL1", "INTS1", "INTS8", "IRAK1", "IRF2BPL", "IRS4", "ISCA2", "ITCH", "ITGA6", "ITM2B", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KATNB1", "KDM1A", "KDM3B", "KDSR", "KIAA0319L", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KLC2", "KMT2A", "KNSTRN", "L2HGDH", "LAMB1", "LAMC1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRP1", "LRPAP1", "LRPPRC", "LRRC8A", "LSS", "LZTFL1", "MACF1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAPK1", "MAPKAPK3", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCM10", "MCM2", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MECR", "MED17", "MED23", "MESD", "MGME1", "MIA3", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MMACHC", "MOCS1", "MOCS2", "MOGS", "MORC2", "MPDZ", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTHFR", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVD", "MYH14", "MYH9", "MYO1E", "MYO5A", "MYO6", "NAA15", "NADK2", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NEMF", "NEU1", "NF1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP56", "NOTCH2", "NPC1", "NPC2", "NPM1", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OSBPL2", "OTULIN", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PARK7", "PARN", "PARS2", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PCNT", "PDCD6", "PDHA1", "PDHB", "PDHX", "PDK3", "PDSS1", "PDSS2", "PEPD", "PEX14", "PEX19", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PISD", "PITRM1", "PKN1", "PKP2", "PLAA", "PLCG2", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POLR3B", "POMGNT2", "POMP", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCA", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRUNE1", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QRICH1", "QRSL1", "RAB11B", "RAB18", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RABL3", "RAC1", "RAD21", "RAD50", "RAF1", "RALA", "RANBP2", "RANGRF", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "RELA", "REPS1", "RFC1", "RFC2", "RHOA", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RNF213", "RP2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS28", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RRP7A", "SACS", "SALL2", "SAMHD1", "SAR1B", "SARS", "SARS2", "SATB2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SCYL1", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC27A4", "SLC2A1", "SLC39A14", "SLMAP", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMG8", "SMN1*", "SMPD4", "SMS", "SNRNP200", "SNRPE", "SNX14", "SOAT1", "SON", "SORD", "SPART", "SPATA5", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SRA1", "SRCAP", "SRP54", "SRP72", "SSBP1", "SSR4", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "STX3", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TAF15", "TAF6", "TALDO1", "TAOK1", "TAP1", "TAP2", "TAPBP", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL2", "TCF20", "TCOF1", "TDP2", "TECR", "TELO2", "TENM3", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM22", "TIMM50", "TIMMDC1", "TJP2", "TKFC", "TKT", "TMCO1", "TMEM126A", "TMEM199", "TMEM43", "TMLHE", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TNRC6A", "TOE1", "TOMM40", "TONSL", "TOP2A", "TOR1A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TPRKB", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIO", "TRIP12", "TRIP13", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSPYL1", "TTC19", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "TXNL4A", "UBA1", "UBA5", "UBE2T", "UBE3A", "UBE4A", "UBE4B", "UBR1", "UBR7", "UBTF", "UFC1", "UFD1", "UGDH", "UGP2", "UMPS", "UNC119", "UNC45A", "UNG", "UPF3B", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP8", "USP9X", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VIPAS39", "VPS13A", "VPS13C", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WASHC4", "WASHC5", "WBP11", "WDR1", "WDR11", "WDR35", "WDR36", "WDR4", "WDR48", "WDR62", "WFS1", "WIPI2", "WNK1", "WRAP53", "XPNPEP3", "XRCC1", "XRCC4", "YARS", "YARS2", "YME1L1", "YWHAE", "YWHAG", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZPR1"], "leading_proteins": ["AAAS", "AARS2", "AASS", "ABCB1", "ABCB7", "ABCD3", "ABCD4", "ACAD9", "ACADVL", "ACAT2", "ACOX1", "ACP2", "ACTN4", "ACY1", "ADAR", "ADD3", "ADNP", "AGK", "AIFM1", "AKAP10", "ALDH18A1", "ALDH2", "ALDH3A2", "ALG1", "ALG11", "ANAPC1", "ANKLE2", "ANO6", "ANXA11", "AP2M1", "AP2S1", "AP3B1", "APOL2", "APP", "ARHGEF2", "ARL2", "ARL6IP1", "ARMC9", "ARSA", "ASAH1", "ASNA1", "ATAD3A", "ATM", "ATP1A1", "ATP2A2", "ATP6AP1", "ATP6V0A2", "ATR", "AURKA", "B3GALT6", "B4GAT1", "BAZ1B", "BCAP31", "BCKDHB", "BCS1L", "BICD2", "BUB1", "BUB1B", "C19orf70", "C1QBP", "CARS", "CASK", "CC2D1A", "CCDC47", "CD109", "CDK13", "CEP290", "CERS1", "CHD7", "CLCC1", "CLCN7", "CLN5", "CLPX", "CNNM4", "COA3", "COMT", "COQ8A", "COX15", "COX2", "COX4I1", "COX6B1", "CPOX", "CPT2", "CRTAP", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CYC1", "DARS2", "DBT", "DCTN4", "DDRGK1", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHX37", "DIABLO", "DICER1", "DKC1", "DNAJB11", "DNM2", "DOCK7", "DPM1", "DPP9", "DSE", "DSG2", "DSP", "DYNC2H1", "EARS2", "ECE1", "EHMT1", "EIF2B2", "EMD", "EPHX2", "ERAP1", "ERCC2", "ERCC3", "ERLIN1", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOC8", "EXOSC2", "EXTL3", "FAM126A", "FANCA", "FANCD2", "FAR1", "FASN", "FDFT1", "FECH", "FKBP10", "FKBP14", "FKRP", "FLII", "FMR1", "FOXRED1", "FUCA1", "FUS", "FXR1", "GAA", "GALE", "GALNT2", "GANAB", "GBA", "GBE1", "GDAP1", "GGCX", "GLA", "GLB1", "GLDC", "GLUD1", "GM2A", "GNPAT", "GNS", "GPAA1", "GPD2", "GUSB", "GYG1", "HADH", "HADHA", "HARS2", "HCCS", "HDAC6", "HEXA", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPS5", "HS2ST1", "HSD17B4", "HTT", "IARS2", "IDH1", "IDH2", "IFT52", "IGBP1", "IGF2R", "INTS1", "IRS4", "ITCH", "ITM2B", "JAGN1", "JUP", "KDSR", "KIAA0319L", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIFBP", "KMT2A", "L2HGDH", "LAMC1", "LAMP2", "LARS", "LAS1L", "LBR", "LETM1", "LMAN1", "LMNA", "LMNB2", "LONP1", "LRBA", "LRPAP1", "LSS", "MAGT1", "MAN2B1", "MAP2K2", "MAPRE2", "MARS2", "MATR3", "MBOAT7", "MCM6", "MECR", "MIA3", "MINPP1", "MIPEP", "MMAB", "MRPL3", "MRPS22", "MRPS25", "MSH6", "MSMO1", "MSTO1", "MTAP", "MTCH1", "MTHFR", "MTO1", "MTOR", "MTR", "MTX2", "NAGLU", "NBAS", "NCAPD3", "ND1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF4", "NDUFB10", "NDUFB3", "NDUFB9", "NDUFS2", "NDUFS8", "NEDD4L", "NEU1", "NF1", "NNT", "NONO", "NPC1", "NPC2", "NSD2", "NSMCE2", "NT5C2", "NUBPL", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP85", "NUP88", "NUP93", "NXN", "OCLN", "OCRL", "OPA1", "P3H1", "P4HA2", "PARN", "PCNT", "PDHA1", "PDHB", "PDHX", "PDK3", "PDSS1", "PDSS2", "PEX14", "PEX19", "PHF6", "PI4KA", "PIGK", "PIGT", "PIGU", "PIK3C2A", "PISD", "PITRM1", "PKP2", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD3", "PMPCA", "PNPLA6", "PNPLA8", "POFUT1", "POLD1", "POLE", "POLR3A", "POMGNT2", "POMP", "PON2", "POP1", "POR", "PPOX", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPT1", "PRCC", "PREPL", "PRKAR1A", "PRKDC", "PRKRA", "PRPF8", "PSAP", "PTCD3", "PTDSS1", "PTPRF", "PUF60", "PUS1", "PUS7", "PXMP2", "PYCR2", "RAB11B", "RAB3GAP2", "RABL3", "RAC1", "RAF1", "RANBP2", "RANGRF", "RAPGEF2", "RARS2", "RBM10", "RBM28", "RBMX", "RDH11", "REPS1", "RHOA", "RINT1", "RMND1", "RNASEH2B", "RNASET2", "RNF2", "RPL10", "RPL15", "RPL21", "RPS23", "RPS6KA3", "RRP7A", "SATB2", "SC5D", "SCARB2", "SCO1", "SCO2", "SDHB", "SEC63", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SIGMAR1", "SLC12A2", "SLC16A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC2A1", "SLC39A14", "SLMAP", "SLTM", "SMARCA4", "SMARCE1", "SMC1A", "SMG8", "SMN1*", "SMPD4", "SNX14", "SOAT1", "SPART", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SSR4", "STAG1", "STAG2", "STAMBP", "STAT1", "STT3A", "STT3B", "STX3", "SUZ12", "SYNE2", "TAF15", "TAOK1", "TAP1", "TAP2", "TARS2", "TBL2", "TECR", "TELO2", "THOC2", "TIA1", "TIMM22", "TIMMDC1", "TMCO1", "TMEM126A", "TMEM199", "TMEM43", "TMLHE", "TMTC3", "TMX2", "TPP1", "TRAPPC11", "TRIO", "TRMU", "TRRAP", "TTC19", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBGCP2", "TWNK", "UBE3A", "UQCRQ", "USP7", "USP8", "VAMP7", "VANGL1", "VIM", "VPS13A", "VPS33A", "VPS51", "WASHC5", "WDR35", "WDR48", "WFS1", "ZMPSTE24"]} \ No newline at end of file diff --git a/msigdb_kegg/advanced/idx2term.json b/msigdb_kegg/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..069502b00cc0f6b10d25cafd0e17be80fbce4fb5 --- /dev/null +++ b/msigdb_kegg/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Lysosome", "1": "Parkinsons disease", "2": "Sphingolipid metabolism", "3": "Steroid biosynthesis", "4": "Peroxisome", "5": "Cardiac muscle contraction", "6": "Huntingtons disease", "7": "Porphyrin and chlorophyll metabolism", "8": "Oxidative phosphorylation", "9": "Abc transporters"} \ No newline at end of file diff --git a/msigdb_kegg/advanced/plot_0.png b/msigdb_kegg/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d1954b9163fce1ed1ca11f10075f1786361ca1a2 --- /dev/null +++ b/msigdb_kegg/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d9a07fbcd005004273be79668235e7c114b23d2c1175538293428b24ceff0da2 +size 201591 diff --git a/msigdb_kegg/advanced/plot_1.png b/msigdb_kegg/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..1cddce12a1417f1a27cfe86527b63da331183fed --- /dev/null +++ b/msigdb_kegg/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f3707c265cdd4f5f833c5be78aa13ffc392e37e260ae9af00e4003356292b6a1 +size 209962 diff --git a/msigdb_kegg/advanced/plot_2.png b/msigdb_kegg/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..504debc22e3f268e4676d2e3e6d14c6b2401e6d8 --- /dev/null +++ b/msigdb_kegg/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fe60bde438b5e402eaad3f53739f21a4fe6981fd375c9919ce228779563df5dd +size 192295 diff --git a/msigdb_kegg/advanced/plot_3.png b/msigdb_kegg/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..4301898cf55aab7c583cdee1e8508d96a3398412 --- /dev/null +++ b/msigdb_kegg/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9503d6db326e84fdd17661f9615fcde5aeed12c62158d169dfa1bd6e440fe30a +size 196173 diff --git a/msigdb_kegg/advanced/plot_4.png b/msigdb_kegg/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..be3ed30b9b5c61405a8f689c1a2529f6c75d0a24 --- /dev/null +++ b/msigdb_kegg/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9e7dd1aa4e8773686b73ad353b0c10fc583b712801889ea0192ae0f4647e9616 +size 197472 diff --git a/msigdb_kegg/advanced/plot_5.png b/msigdb_kegg/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..afc788c7095f9ca376a733a5c3263d86bd16adc4 --- /dev/null +++ b/msigdb_kegg/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b7e4a17e41e85ee2e6e828f180da792e22a8cb6ecf128e0bb4ea5e685d6008de +size 199864 diff --git a/msigdb_kegg/advanced/plot_6.png b/msigdb_kegg/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..5131a63653e8f50b31a79faeb106fc071bd51a21 --- /dev/null +++ b/msigdb_kegg/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba5b73058d4cfc1d34de5c40671298894eff725a13a8922bd82289043fcd27d8 +size 215323 diff --git a/msigdb_kegg/advanced/plot_7.png b/msigdb_kegg/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..5ffc2ab90ac9d4fae278a95ebecb19b9d68bb6c2 --- /dev/null +++ b/msigdb_kegg/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3a45e76dd16ab8b04c8097e0a92f1d5ce00ae324902e376157230c155e37e1b5 +size 199949 diff --git a/msigdb_kegg/advanced/plot_8.png b/msigdb_kegg/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..dac7500b33017feb12cf43cb4340caeb2b0ad571 --- /dev/null +++ b/msigdb_kegg/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9b3b59129d2c38b5fb78468b6ab03052a65569e384e0098a229c9dd473c197c7 +size 206976 diff --git a/msigdb_kegg/advanced/plot_9.png b/msigdb_kegg/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..f7c55e872139161aeab0629a79f3c6572845602d --- /dev/null +++ b/msigdb_kegg/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90995afe37cbf37878aba4e3ea2e930bcf14e419d70fb64e740f6df826656024 +size 184974 diff --git a/msigdb_kegg/basic/idx2term.json b/msigdb_kegg/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..000c16ebffc86f4584e8191c4f514f0d8754fa50 --- /dev/null +++ b/msigdb_kegg/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Lysosome", "1": "Parkinsons disease", "2": "Sphingolipid metabolism", "3": "Steroid biosynthesis", "4": "Peroxisome", "5": "Cardiac muscle contraction", "6": "Huntingtons disease", "7": "Porphyrin and chlorophyll metabolism", "8": "Oxidative phosphorylation", "9": "Abc transporters", "10": "Calcium signaling pathway", "11": "Snare interactions in vesicular transport", "12": "Alzheimers disease", "13": "N glycan biosynthesis", "14": "Antigen processing and presentation", "15": "Glycerophospholipid metabolism", "16": "Biosynthesis of unsaturated fatty acids", "17": "Ppar signaling pathway", "18": "Mtor signaling pathway", "19": "Lysine degradation", "20": "P53 signaling pathway", "21": "Progesterone mediated oocyte maturation"} \ No newline at end of file diff --git a/msigdb_kegg/basic/plot_0.png b/msigdb_kegg/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..0b0ee61a8634e1c7c54abf391fd47415af2727e2 --- /dev/null +++ b/msigdb_kegg/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:31aa6197bd6fca2ed1456f5f4be1bb9ceb21aedd8ec7e4b4f71d5bc7c6fb54e1 +size 137629 diff --git a/msigdb_kegg/basic/plot_1.png b/msigdb_kegg/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..ffe4f85798b5f69758f4b525d681affc87b64b94 --- /dev/null +++ b/msigdb_kegg/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a4975078a4248c62ee58ed1df1f076b355224d6ed0f00127f6a5657602f59c97 +size 147988 diff --git a/msigdb_kegg/basic/plot_10.png b/msigdb_kegg/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..4d5af550e9b49e2fcb67e622e47e69b3a2351f87 --- /dev/null +++ b/msigdb_kegg/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:47d09ecc5c56dd9a45b5e2b8db7a2002b2bd49cae9a850d253fafc4f8f47c8a3 +size 135070 diff --git a/msigdb_kegg/basic/plot_11.png b/msigdb_kegg/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..20ecaac5c9cac1f57bdf91ec89d00776ee6c44e1 --- /dev/null +++ b/msigdb_kegg/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d41e5f248b9d380ffd063aa07da3ce883a80ea7f54a84717643602da914765a0 +size 138208 diff --git a/msigdb_kegg/basic/plot_12.png b/msigdb_kegg/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..232799ddbd85c2ccc993b1b890a0047dc98ca91c --- /dev/null +++ b/msigdb_kegg/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f0440db430dee725cae86f37775c2dd9cdd316fd91845a4a696daa05e099193a +size 143149 diff --git a/msigdb_kegg/basic/plot_13.png b/msigdb_kegg/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..cfa69832231e367b186c99ad6b41abb252676f41 --- /dev/null +++ b/msigdb_kegg/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2e729ca7c3241a44edbe3a467f8ed3c0f6ea4651387abcd7f6cfd6d441d70959 +size 136650 diff --git a/msigdb_kegg/basic/plot_14.png b/msigdb_kegg/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..b2e528c8974b661a9f2b8048f30aac348f33102d --- /dev/null +++ b/msigdb_kegg/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d926d76795cfe5d90a9e6dd6d27d4d51413bd7e0ae9a8af7988958e89a5a183 +size 150970 diff --git a/msigdb_kegg/basic/plot_15.png b/msigdb_kegg/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..9d35bcf2ba0ff074c61c7eb26f60407238810c05 --- /dev/null +++ b/msigdb_kegg/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:200e455ef16f73cfebc85e9414b18f5fa9b561c2183a78278b46a92f7f79c1b9 +size 146219 diff --git a/msigdb_kegg/basic/plot_16.png b/msigdb_kegg/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..dea83c7630595fcf2f236a2a9de8419143a7bd1f --- /dev/null +++ b/msigdb_kegg/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2a3e9c643500a5544804e93e55e2f1e587f4d356d29b1cc908ed387ce6da928c +size 145700 diff --git a/msigdb_kegg/basic/plot_17.png b/msigdb_kegg/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..5a94fa45f27081f30fc531e0c66330058feab5c4 --- /dev/null +++ b/msigdb_kegg/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:747d92093c8166fe820d69a34898a19a1287d5d8d74712e685f4400f456af0ef +size 143115 diff --git a/msigdb_kegg/basic/plot_18.png b/msigdb_kegg/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..ece386844805f5cf9cfa99774b8510a5b1b40066 --- /dev/null +++ b/msigdb_kegg/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e5c4c7f3a69d0dd021b62d36ef2c501ced3735a370ed1be297568609a79641bb +size 145908 diff --git a/msigdb_kegg/basic/plot_19.png b/msigdb_kegg/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..82b0124af2c5df67d054ef6826dd6ff1acb2199d --- /dev/null +++ b/msigdb_kegg/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:11de16c46a0279ef78f967ff04b040168c686df2ca4a5228510563f951f5cbf8 +size 141394 diff --git a/msigdb_kegg/basic/plot_2.png b/msigdb_kegg/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..0b7b608715d34a089e80f84b732eb8d59b6431f7 --- /dev/null +++ b/msigdb_kegg/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3356abfa39efb1f4efd33962eb688b323788a76a4b98c386139541065c7ccae1 +size 142896 diff --git a/msigdb_kegg/basic/plot_20.png b/msigdb_kegg/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..93a814a2c9a33224199588616a209b241ef7cf2c --- /dev/null +++ b/msigdb_kegg/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:68ec2e5a182f26c85272caf50e77f3f631d2fc7c1d1e5a05f2c6e9362ca6864d +size 149099 diff --git a/msigdb_kegg/basic/plot_21.png b/msigdb_kegg/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..f25e6fcdc71ad6888cd5cd9d577d7385038f74df --- /dev/null +++ b/msigdb_kegg/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5dde74223f53fe488068235bb1cc9d005555723450fcf1ce481d7558d94e54d3 +size 156440 diff --git a/msigdb_kegg/basic/plot_3.png b/msigdb_kegg/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..d941188949643694143df19f35e0021f8cbb55b5 --- /dev/null +++ b/msigdb_kegg/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2b3e61b6590220c9adfa1de69c4c1fffb92662f5bcf59a603d9cddce29e9eaf2 +size 137292 diff --git a/msigdb_kegg/basic/plot_4.png b/msigdb_kegg/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..3ade91752eb3bc9092dd9f70f448bfb8a57332f8 --- /dev/null +++ b/msigdb_kegg/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:721bd460fb3af006391770d16c15a2b89cc345d28d8fc2d1084c380f25b93d5b +size 133348 diff --git a/msigdb_kegg/basic/plot_5.png b/msigdb_kegg/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..65670353d26424724e14e1ec57aabad41afcd231 --- /dev/null +++ b/msigdb_kegg/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c81e5eb8f6ccc3a3220aaee482e39ddd37eefd51a3c71b65bbd06785316269f2 +size 140977 diff --git a/msigdb_kegg/basic/plot_6.png b/msigdb_kegg/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..ddd1be018d05bd1bdb8aaed406f1e135d5af5506 --- /dev/null +++ b/msigdb_kegg/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5c0b4d325794bdb6ddb069331d69c95d63fefc1f5975b5febd86c7f515a4ae77 +size 141438 diff --git a/msigdb_kegg/basic/plot_7.png b/msigdb_kegg/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..1f446305dbd10eeb7fe0737a178d36a0050cc455 --- /dev/null +++ b/msigdb_kegg/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cc338d0f5b33506aff5d08596e34cc871ba5b586f93c3c19d431c0be71f262e7 +size 139130 diff --git a/msigdb_kegg/basic/plot_8.png b/msigdb_kegg/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..9b07f6e91cd97b010aa33351aa2669100db4acdd --- /dev/null +++ b/msigdb_kegg/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:442e7881e34da7d933f8a00dc96b684c39af5ccc1f77d3962aa27d4b924da832 +size 144831 diff --git a/msigdb_kegg/basic/plot_9.png b/msigdb_kegg/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..7ddd3be55a696f96cdd1ca2ac21607d147d3d88b --- /dev/null +++ b/msigdb_kegg/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d83cbcd6fe025fbf75c09afb373c3d738cdbdc97f8f93c1d6411c368a0747fa3 +size 131267 diff --git a/msigdb_kegg/consensus.joblib b/msigdb_kegg/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..37c69f46729fd5697bd92508c06ac2de8ec4174f --- /dev/null +++ b/msigdb_kegg/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f795ce7b08ec680c046ee798bf08e8e7bf4c03528d09b307d7586796eecdfa2f +size 98374 diff --git a/msigdb_kegg/df_merge.tsv b/msigdb_kegg/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..0e0ee190931a2aa06a725b4c074d9bf807e332f7 --- /dev/null +++ b/msigdb_kegg/df_merge.tsv @@ -0,0 +1,14 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Lysosome 23 50 4.762281362195986 1.914165393968048e-06 21.740291262135923 48.609223300970875 0.8281821627988494 0.1302152537326229 7.142313942893836 4.247239237941681 3.086075071395461 0.2389623217115766 2.5675730342406308e-12 0.0013677912764436 5.299669654941412e-06 1.834802447124027e-09 5.210697367412818e-12 +Parkinsons disease 17 55 2.829680169213986 0.0046594556991794 16.90776699029126 54.04126213592233 1.0315348591123816 0.3152611195514452 7.595108151251147 4.223805209268991 1.8494970521239744 0.3626807692210581 0.0005925178258993 0.0015835716265251 6.487123062878493e-05 0.0002025669136197 2.001607730797324e-06 +Sphingolipid metabolism 10 12 2.806618412005536 0.0050064508321938 5.672330097087379 11.759708737864075 0.9805985471070467 0.1821702203806468 2.452838935293596 1.3449033287601222 1.7625559835482287 0.2542774311591588 5.118556785874719e-05 0.0065792573185243 0.0018000470176383 0.0222629680099487 1.4416472873703857e-06 +Other glycan degradation 4 8 2.5337667012743816 0.0112843832513325 3.966019417475728 7.12378640776699 0.0449593300314452 0.158186848086018 1.7909726921672984 0.8075596903062239 1.9584092358200416 0.2320333335657103 0.0004793920471104 0.0020655426456597 0.0080257871552124 0.0042908003473226 0.0003706302782608 +Steroid biosynthesis 7 13 2.527787850506816 0.0114783687751109 4.451456310679611 10.919902912621358 0.8535439655720318 0.1867209176898754 2.1463612955879627 1.3314318120676296 1.5430058140543457 0.1933818217769055 1.125360606615866e-06 0.066549445548378 0.0080257871552124 1.3950047231960685e-05 6.875137584646856e-08 +Glycosaminoglycan degradation 4 6 2.425806058360533 0.0152744304345 3.407766990291262 5.864077669902913 0.1350713234786387 0.1703873780123549 1.3379225542760151 0.7043353086258667 1.932540087143412 0.2532951180616937 1.1107568426286228e-05 0.0573151884822011 0.0058956460302812 0.0026887292270871 0.0001590313802548 +Peroxisome 12 35 2.409052000755935 0.0159940189167633 8.944174757281553 33.31553398058252 0.1912181674752777 0.455069334940637 4.249990296795741 4.279943228040891 1.217274798105213 0.3271299230574079 0.034866334504973 0.0402962873689797 0.1333872493386999 0.2116843105930206 0.0002655559882184 +Cardiac muscle contraction 7 21 2.40864475765846 0.0160118749906081 7.728155339805825 19.856796116504853 1.0644813600437804 0.240240383706381 3.4195161605095614 1.765741250102918 1.6465694074711887 0.3002212677564749 0.0080686906789026 0.1988423464133734 0.0096414106757913 0.0236436874746125 0.0013003096338674 +Huntingtons disease 18 81 2.244151980431239 0.0248226244491724 19.631067961165048 76.91504854368932 0.635715043905642 0.4301008974270168 9.08454389027927 5.4148363920790175 1.5734816663041495 0.3870978376334237 0.008950432602752 0.0059901365409964 0.0034006504928382 0.0035308958299045 0.0001075482170372 +Porphyrin and chlorophyll metabolism 8 14 2.151728841485264 0.0314187171835236 3.728155339805826 13.315533980582524 1.2215621624941897 0.2689555702886888 1.770547470360957 1.4201912411596824 1.0389071586082248 0.2908939383930566 0.002032754568143 0.0937235599037543 0.0161297090986061 0.0120645849010356 0.000277756887713 +Oxidative phosphorylation 19 61 2.129404529535305 0.0332208060368524 18.79854368932039 59.0752427184466 1.0149760730411637 0.3252836463038503 7.263801581344288 4.652138947381941 1.8018345229041028 0.3643612228552857 0.0001365197827239 0.0139189683537814 0.000508180078871 4.058171311285695e-05 2.001607730797324e-06 +Abc transporters 5 8 2.0359384062619497 0.0417565406200859 2.3762135922330097 6.366504854368932 0.6645221155900782 0.3307647417699358 1.8079428939478197 2.1798157082242287 1.1702884010083077 0.2791394174824396 0.002032754568143 1.0 1.0 0.0120645849010356 0.01439805670462 +Calcium signaling pathway 6 19 1.9847510772022108 0.0471721729827598 5.735436893203883 16.946601941747574 1.0005800740695592 0.3113014190776675 2.984654368989517 2.3866666657890168 1.2450167285670062 0.3187454651207294 0.1080596296621402 0.0402962873689797 0.1333872493386999 0.2116843105930206 0.0377265240835835 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..f530ee6bc02a9e671f8510398c58dd50a3cace09 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 181, + "title": "Average number of proteins per term", + "value": 18.23204419889503 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..0e51e76b06a4c653aa92b83cced3f8b8fa56a956 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ea17f4007f61d4b22fb4220aab07d3bc1b39f6ff --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,58 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosome 0.6775766341546435 4.762281362195986 1.914165393968048e-06 0.0003464042560898 0.0003464639363083 50 P06865,P06280,P50897,P08236,P04062,O14773,P07602,P16278,Q9Y487,P10253,Q14108,P17900,Q9NZJ7,Q99519,P15586,P54802,Q8NCC3,Q93050,P10619,O75503,P13473,O15118,Q13510 23 +Glycosaminoglycan biosynthesis chondroitin sulfate 0.9022753792298636 2.9762893390201093 0.0029175945241433 0.4107215631619275 0.0909326740327455 2 Q9UL01 1 +Parkinsons disease 0.4740318168532421 2.829680169213986 0.0046594556991794 0.5705854067765215 0.0909326740327455 55 O75306,P14406,P51970,Q9Y6M9,P21796,P24539,P08574,P03886,Q9UDW1,P14854,P45880,P13073,O43676,Q9Y277,P12235,O14949,P00403 17 +Sphingolipid metabolism 0.812150403063951 2.806618412005536 0.0050064508321938 0.5968487760271999 0.0909326740327455 12 Q06136,O15269,O15270,P16278,Q99519,P06280,O43681,O95470,Q13510,P04062 10 +Glycosphingolipid biosynthesis ganglio series 0.8992520486683225 2.556186708952652 0.0105826318764983 0.8542210334518656 0.0989326070616709 3 P16278 1 +Other glycan degradation 0.8277500857292904 2.5337667012743816 0.0112843832513325 0.8717898839655956 0.0989326070616709 8 Q9BTY2,P16278,P06865,P04062 4 +Steroid biosynthesis 0.7418259916498396 2.527787850506816 0.0114783687751109 0.8762634321011564 0.0989326070616709 13 P37268,Q16850,Q15392,Q15800,Q14534,P35610,O76062 7 +Glycosphingolipid biosynthesis globo series 0.8878157189510294 2.5064080636414134 0.0121964770935587 0.8915140999833238 0.0991981519808072 3 P06865 1 +Glycosaminoglycan degradation 0.9085921666625288 2.425806058360533 0.0152744304345 0.9383328437541428 0.1061268892002113 6 P06865,P16278,P15586,P54802 4 +Peroxisome 0.5006002932805095 2.409052000755935 0.0159940189167633 0.9459755174022229 0.1061268892002113 35 A8MXV4,O75874,O14678,O14975,P48735,O14734,P28288,O15228,Q96K12,Q9NR77,O15254,Q15067 12 +Cardiac muscle contraction 0.6049505171334322 2.40864475765846 0.0160118749906081 0.9461526703320812 0.1061268892002113 21 P14406,P08574,Q9UDW1,P16615,P13073,O14949,P00403 7 +Alpha linolenic acid metabolism 0.8362999708199488 2.2787508352204884 0.0226818809872413 0.984278027478764 0.1172977273911623 3 O15254,Q15067 2 +Steroid hormone biosynthesis 0.8326728231046403 2.2625112371116476 0.0236658353603664 0.9868983467590722 0.1189865611173981 3 Q53GQ0 1 +Huntingtons disease 0.3708373302367412 2.244151980431239 0.0248226244491724 0.9894285473889872 0.1214295952783843 81 P14406,O75306,Q9Y6M9,P51970,P12236,P21796,Q9UDW1,P24539,P08574,P14854,P45880,P13073,Q9UJW0,O43676,Q9Y277,P12235,O14949,P00403 18 +Porphyrin and chlorophyll metabolism 0.6607926770689008 2.1517288414852636 0.0314187171835236 0.9969052249001896 0.1496523107952046 14 P53701,Q5JPH6,P30519,Q7KZN9,P22830,Q96EY8,P09601,P08236 8 +Oxidative phosphorylation 0.4087510504380059 2.129404529535305 0.0332208060368524 0.9977907723702524 0.1541786126325714 61 P51970,P24539,Q7KZN9,O43676,O14949,P00403,O75306,Q86Y39,P08574,Q9Y487,O75964,P14406,Q9Y6M9,P03886,Q9UDW1,P13073,Q93050,Q15904,P14854 19 +Folate biosynthesis 0.7984596334826229 2.1079878048696217 0.0350320443116793 0.9984266208332264 0.1576684158717499 3 P00374 1 +Primary immunodeficiency 0.7908123794340426 2.0731217200562777 0.0381609531034761 0.9991259524118822 0.1606309886448645 3 Q03519 1 +Abc transporters 0.7276158051171654 2.0359384062619497 0.0417565406200859 0.99955625720783 0.1717712239144444 8 P08183,O14678,Q03519,Q03518,Q9NUT2 5 +Glycosaminoglycan biosynthesis heparan sulfate 0.7799599015042376 2.0234412957849885 0.0430276702251288 0.9996510301618046 0.1730668513499628 3 Q7LGA3 1 +Calcium signaling pathway 0.5578434382298839 1.9847510772022108 0.0471721729827598 0.9998409212362372 0.1856122458669465 19 P20020,P21796,P45880,P16615,Q9Y277,P12235 6 +Cell adhesion molecules cams 0.6473301816879284 1.9018010744490053 0.0571971657769925 0.9999765480384049 0.2070537401127129 12 P01889,Q16625,P04439,Q92896 4 +Nicotinate and nicotinamide metabolism 0.8033624731671125 1.8745840327827716 0.0608499715224057 0.9999883846939414 0.2159577420697146 5 Q13423,P43490 2 +Snare interactions in vesicular transport 0.6546305445055438 1.7892436345538905 0.0735755872094428 0.999999016875876 0.2421305688165299 10 Q86Y82,Q13190,Q9P2W9,Q13277,O95249,O15498,Q9UNK0,P51809 8 +Cytokine cytokine receptor interaction 0.6432322053675676 1.7134692016008264 0.0866262546767502 0.9999999245980108 0.2657517304490134 2 P49327 1 +Renin angiotensin system 0.7768172538933615 1.67905481478873 0.0931413613099738 0.9999999793620484 0.2809764399517545 4 Q9UIQ6,P10619 2 +Autoimmune thyroid disease 0.7691185055458051 1.645751378840437 0.0998149562508754 0.9999999945793104 0.2822891731470071 4 P01889,P04439,P10321 3 +Allograft rejection 0.7691185055458051 1.645751378840437 0.0998149562508754 0.9999999945793104 0.2822891731470071 4 P01889,P04439,P10321 3 +Graft versus host disease 0.7691185055458051 1.645751378840437 0.0998149562508754 0.9999999945793104 0.2822891731470071 4 P01889,P04439,P10321 3 +O glycan biosynthesis 0.7416812609456883 1.5265199814143604 0.1268804180876102 0.9999999999784054 0.3328312416501078 4 O43505,Q8N4A0,Q10472 3 +Alzheimers disease 0.3529832984810309 1.4333502122922868 0.1517577790515496 0.9999999999998846 0.3711913244368984 62 P14406,P51970,Q9Y6M9,P24539,P08574,Q9UDW1,P05067,P14854,P16615,P13073,O43676,O14949,P00403 13 +Hypertrophic cardiomyopathy hcm 0.5694057675021591 1.3781705142795937 0.1681506485680306 0.9999999999999968 0.3952632128677084 11 P54646,P16615 2 +N glycan biosynthesis 0.4948445996890602 1.3489231742530252 0.1773616437858713 0.9999999999999996 0.4063602218385154 17 Q86YN1,O60476,Q16706,O60762,Q9BT22,P04844,O60512,P46977,Q2TAA5 9 +Glutathione metabolism 0.4427369472795942 1.2873383672659393 0.1979763761740973 1.0 0.4233007849917876 23 O75874,O15217 2 +Riboflavin metabolism 0.6299685544668585 1.1631806708702546 0.244756207153457 1.0 0.485519080892608 6 Q9NPH0 1 +Regulation of autophagy 0.5462720516259972 1.0820718160492635 0.2792206180632923 1.0 0.5120826567253064 8 P54646 1 +Metabolism of xenobiotics by cytochrome p450 0.5264068193444198 1.07378602495915 0.2829185948758599 1.0 0.5120826567253064 10 O15217 1 +Antigen processing and presentation 0.4310363675936426 0.983639836150774 0.3252926310290158 1.0 0.5401648276720354 18 Q9UL46,P10321,P01889,P04439,Q03519,Q03518,P07900 7 +Proximal tubule bicarbonate reclamation 0.5514836137677515 0.9415763616284802 0.3464095767723296 1.0 0.5598226196052828 7 Q9UBX3,P05023 2 +Glycerophospholipid metabolism 0.430583055306715 0.9075255995711452 0.3641289183311649 1.0 0.5675329231230885 17 Q9UG56,P52429,P48651,Q8NCC3,O15228,Q8NF37,Q96N66 7 +Biosynthesis of unsaturated fatty acids 0.5030365013938147 0.8964849038434103 0.3699938393841129 1.0 0.5675329231230885 9 Q53GQ0,O95864,O15254,Q9NZ01,Q15067 5 +One carbon pool by folate 0.4815724773258347 0.873171471883525 0.3825696219195977 1.0 0.5750778513704854 11 Q99707,P00374 2 +Type i diabetes mellitus 0.579143086644789 0.8697367031560493 0.3844443094797167 1.0 0.5750778513704854 5 P01889,P04439 2 +Basal cell carcinoma 0.4463243873979038 0.6898954410139462 0.4902599430309495 1.0 0.6576338698109622 2 P35222 1 +Vibrio cholerae infection 0.3603047373813874 0.6704405464090997 0.5025769946388015 1.0 0.659177072678428 24 O43731,Q9Y487,P24390 3 +Ppar signaling pathway 0.37389184169239 0.6522678396651879 0.5142284029804269 1.0 0.6696067693486134 19 P23786,O14975,O95864,O15254,Q15067 5 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.5068684049164418 0.5621804447781494 0.5739930834987133 1.0 0.7256675684087629 5 O43292 1 +Mtor signaling pathway 0.4014000356628419 0.5572359067716607 0.5773662599281602 1.0 0.7256675684087629 14 P42345,Q15418,P54646,P51812,P23588 5 +Lysine degradation 0.3274253707404926 0.5053689001412696 0.6132997580316748 1.0 0.7500490284036023 27 Q9NVH6,P05091,P51648,Q9BWD1,O96028,P35610 6 +P53 signaling pathway 0.3676575865004095 0.448252738338308 0.6539708052408093 1.0 0.7787415509775427 16 P42574,P14635,Q13315,Q13535,O95067,P31350,P49327 7 +Galactose metabolism 0.3614826102719547 0.3400986462741643 0.7337822411976513 1.0 0.8405986433973095 14 P10253,Q14376,P16278,P06280 4 +Protein export 0.3409946721855568 0.2680445244716265 0.7886650467008829 1.0 0.8811627990917271 15 P67812,Q15070 2 +Viral myocarditis 0.3436926080724118 0.2069164268120542 0.8360751273913813 1.0 0.919416767802262 12 P01889,P10321,P04439 3 +Amyotrophic lateral sclerosis als 0.3513112729502022 0.2002732270926206 0.8412669000461208 1.0 0.919416767802262 10 Q9BUN8 1 +Progesterone mediated oocyte maturation 0.2773715718619515 0.1863884441901706 0.8521401538470212 1.0 0.9235770529719212 29 Q9UJX4,P04049,Q15418,O43683,Q9UJX2,Q13042,O95067,P53350,P51812,P07900 10 +Vasopressin regulated water reabsorption 0.2994492959544631 0.1063701300936451 0.915288691329578 1.0 0.9631817042479864 16 Q9UJW0 1 +Arrhythmogenic right ventricular cardiomyopathy arvc 0.2739038014246323 0.0287928711363136 0.9770297865334824 1.0 1.0 17 P50402,Q99959,P16615 3 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..7db9f02bd0d51e0bf75f3dfac3e9e130ce8ab28c --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTN1", "ACTN2", "ACTN4", "ACY1", "ADAR", "ADH5", "ADI1", "ADK", "ADO", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPAT4", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALYREF", "AMPD2", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEX1", "APIP", "APP", "APRT", "AQR", "ARAP1", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATG7", "ATIC", "ATM", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATR", "AURKA", "B3GALT6", "B4GALT3", "B4GAT1", "BAIAP2", "BAX", "BCAS2", "BCAT1", "BCAT2", "BCKDHB", "BCR", "BDH2", "BECN1", "BIRC6", "BLM", "BLVRA", "BPNT1", "BRCA1", "BRD8", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2D", "CAMK2G", "CANX", "CAPN1", "CAPN2", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CBL", "CBR1", "CCDC6", "CCNB1", "CCNB2", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC40", "CDC42", "CDC5L", "CDC6", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CETN2", "CFL1", "CFL2", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHMP5", "CHORDC1", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT10", "CNOT3", "CNOT4", "CNOT7", "COASY", "COMT", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPOX", "CPT1A", "CPT2", "CREBBP", "CRK", "CRKL", "CRNKL1", "CROT", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CXADR", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBT", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCXR", "DDB1", "DDOST", "DDX23", "DDX39B", "DDX3X", "DDX42", "DDX46", "DDX5", "DDX6", "DERA", "DERL1", "DFFA", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX38", "DHX8", "DIAPH1", "DIAPH2", "DIAPH3", "DIS3", "DLAT", "DLD", "DLST", "DNM1L", "DNM2", "DNMT1", "DOLPP1", "DPM1", "DPYSL2", "DPYSL5", "DSC2", "DSE", "DSG2", "DSP", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "ELOB", "EMD", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "ERBIN", "ERCC2", "ERCC3", "ERO1A", "ESPL1", "EXO1", "EXOC3", "EXOC4", "EXOC7", "EXOG", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "FABP5", "FADS2", "FAH", "FAR1", "FAR2", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FH", "FLAD1", "FLCN", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FUCA1", "FUCA2", "G6PD", "GAA", "GABARAPL2", "GALE", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GBA", "GBE1", "GCAT", "GCDH", "GCLC", "GCLM", "GFPT1", "GGA1", "GGA2", "GGCT", "GGH", "GLA", "GLB1", "GLDC", "GLG1", "GLO1", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPI", "GPT2", "GRB2", "GRHPR", "GSK3A", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTSE1", "GUSB", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HCCS", "HDAC1", "HDAC2", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIP1", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMBS", "HMGB1", "HMGCL", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA3", "HNRNPC", "HNRNPK", "HNRNPM", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUWE1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGF2BP1", "IGF2R", "IKBKB", "ILK", "IMPDH2", "INPP4A", "INPPL1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRS4", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "ITPK1", "IVD", "JUP", "KARS", "KDELR1", "KDELR3", "KDSR", "KIDINS220", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARS", "LARS2", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LIG1", "LIG3", "LIPA", "LLGL1", "LMNA", "LNPEP", "LPCAT1", "LPCAT4", "LRP1", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LYPLA1", "LYPLA2", "M6PR", "MAGED1", "MAN1A2", "MAN2A1", "MAN2B1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAVS", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "ME1", "ME2", "MGST2", "MGST3", "MID1", "MIF", "MINPP1", "MMAB", "MOGS", "MPDZ", "MPHOSPH6", "MPI", "MPST", "MRE11", "MRPL13", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTAP", "MTCH1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFR", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVD", "MYH10", "MYH14", "MYH9", "MYL6", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NBN", "NCAM1", "NCBP1", "NCBP2", "NCKAP1", "NCL", "NCSTN", "ND1", "NDUFA10", "NDUFA11", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEU1", "NF1", "NIT2", "NLN", "NME1", "NME3", "NME7", "NNT", "NOTCH2", "NPC1", "NPC2", "NRP1", "NSD2", "NSDHL", "NSF", "NT5C2", "NT5C3A", "NUDT19", "NUDT5", "NUDT9", "OAT", "OCLN", "OCRL", "OGDH", "ORC3", "OXA1L", "OXCT1", "P4HA1", "P4HA2", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PARS2", "PATL1", "PC", "PCBP1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDCD6IP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDSS1", "PDSS2", "PEX14", "PEX19", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHGDH", "PI4KA", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PKP2", "PLA2G15", "PLCG1", "PLCG2", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLXNB2", "PMPCA", "PMVK", "PNP", "PNPLA4", "PNPT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POMP", "PPA1", "PPA2", "PPAT", "PPID", "PPIE", "PPIH", "PPIL2", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP5C", "PPT1", "PQBP1", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKDC", "PRPF18", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PRUNE1", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTDSS1", "PTDSS2", "PTGES2", "PTPN1", "PTPN11", "PTPRF", "PUF60", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "RAB11B", "RAB13", "RAB23", "RAB3B", "RAB4A", "RAB5B", "RAB5C", "RABEP1", "RAC1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAF1", "RALA", "RAPGEF2", "RARS", "RARS2", "RB1", "RBM17", "RBM22", "RBM25", "RBM8A", "RBMX", "RCOR1", "RDH11", "RDX", "RELA", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHEB", "RHOA", "RIPK1", "RNASEH2A", "RNASEH2B", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RUFY1", "RUVBL1", "SAE1", "SARS", "SARS2", "SART1", "SC5D", "SCARB2", "SCD", "SCP2", "SDHA", "SDHB", "SEC11A", "SEC22B", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEPHS1", "SETD1A", "SETD2", "SETD7", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHMT1", "SHMT2", "SIN3A", "SIPA1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SLK", "SLTM", "SLU7", "SMAP1", "SMC1A", "SMC3", "SMNDC1", "SMPD4", "SMS", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORD", "SORT1", "SPCS2", "SPCS3", "SPR", "SPTAN1", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRA", "SRPRB", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SYMPK", "TAB1", "TAF6", "TAF6L", "TALDO1", "TAOK1", "TAP1", "TAP2", "TAPBP", "TARS", "TARS2", "TARSL2", "TCERG1", "TECR", "TFAM", "TFG", "TFRC", "THOC1", "THOC2", "THOC3", "THOP1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM7SF2", "TMLHE", "TOMM40", "TP53", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPR", "TRA2A", "TRA2B", "TRAF2", "TRIM25", "TRIP12", "TRMT11", "TROVE2", "TSG101", "TSPO", "TSTA3", "TTC37", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TXNDC12", "TXNL4A", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBR5", "UCK2", "UGDH", "UGP2", "ULK3", "UMPS", "UNC45A", "UNG", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USP39", "USP8", "VAMP7", "VANGL1", "VAPA", "VARS1", "VARS2", "VASP", "VCL", "VDAC1", "VDAC2", "VDAC3", "VPS25", "VPS28", "VPS37B", "VPS45", "VPS4A", "VPS4B", "WARS", "WASF2", "WBP11", "WDR61", "WWP2", "XAB2", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YES1", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZFYVE16", "ZMAT2", "ZYX"], "leading_proteins": ["ABCB1", "ABCB8", "ABCD3", "ABCD4", "ACAT2", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ALDH2", "ALDH3A2", "ALG1", "ALG11", "ANAPC5", "APP", "ASAH1", "ASNA1", "ATM", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5F1", "ATP5L", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATR", "B4GALT3", "B4GAT1", "BUB1", "CASP3", "CCNB1", "CCNB2", "CDC16", "CDC23", "CLN5", "COX15", "COX2", "COX4I1", "COX6B1", "COX7A2", "CPT2", "CTNNB1", "CTSA", "CYC1", "CYP51A1", "DCTN4", "DERL1", "DGKE", "DHCR24", "DHFR", "DOLPP1", "DPM1", "DSE", "EARS2", "EIF4B", "EMD", "FADS2", "FAR2", "FASN", "FDFT1", "FECH", "FUCA2", "GAA", "GALE", "GALNT1", "GALNT4", "GBA", "GLA", "GLB1", "GLG1", "GM2A", "GNPAT", "GNS", "GOSR1", "GPAA1", "GSTA4", "GUSB", "HCCS", "HEXA", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HMOX2", "HS2ST1", "HSD17B12", "HSP90AA1", "IDH1", "IDH2", "KDELR1", "KDELR3", "KDSR", "LAMP2", "LNPEP", "LPCAT1", "MAN1A2", "MAN2A1", "MBOAT7", "MMAB", "MSMO1", "MTCH1", "MTOR", "MTR", "NAGLU", "NAMPT", "ND1", "NDUFA11", "NDUFA8", "NDUFB3", "NDUFB9", "NDUFS2", "NEU1", "NNT", "NPC1", "NSD2", "NUDT19", "OCLN", "OXA1L", "PISD", "PKP2", "PLA2G15", "PLK1", "PPT1", "PRKAA2", "PSAP", "PSME2", "PTDSS1", "PXMP2", "RAF1", "RPN2", "RPS6KA1", "RPS6KA3", "RRM2", "SCARB2", "SEC11A", "SGPL1", "SLC25A10", "SLC25A4", "SLC25A6", "SLC27A2", "SOAT1", "SPTLC1", "SPTLC2", "SQLE", "STT3A", "STX12", "STX18", "STX3", "STX5", "STX8", "TAP1", "TAP2", "TECR", "TM7SF2", "TMLHE", "TPP1", "UQCR10", "UQCRQ", "VAMP7", "VDAC1", "VDAC2", "VDAC3", "YKT6"]} \ No newline at end of file diff --git a/msigdb_reactome/advanced/idx2term.json b/msigdb_reactome/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9a8749caa7d5d6ec59e29aec79ba4bc03158a324 --- /dev/null +++ b/msigdb_reactome/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Protein localization", "1": "Metabolism of lipids", "2": "Sphingolipid metabolism", "3": "Mitochondrial protein import", "4": "Glycosaminoglycan metabolism", "5": "Glycosphingolipid metabolism", "6": "Slc mediated transmembrane transport", "7": "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "8": "Mitochondrial calcium ion transport", "9": "Phospholipid metabolism"} \ No newline at end of file diff --git a/msigdb_reactome/advanced/plot_0.png b/msigdb_reactome/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..584c1b74b186521da160981d4635339516efe759 --- /dev/null +++ b/msigdb_reactome/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dc8eb79ff28497454b75570ad4e27d17569e7d731fb8ea67577baf4b516f3956 +size 207427 diff --git a/msigdb_reactome/advanced/plot_1.png b/msigdb_reactome/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..d9c4f5afac29e2d068b06f081fe77802cf0fa61b --- /dev/null +++ b/msigdb_reactome/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4a70b03000294b0beb7205e7d49826781ffc6dbe41da7d9b231ec2fe81be936d +size 222715 diff --git a/msigdb_reactome/advanced/plot_2.png b/msigdb_reactome/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..6d7711e35afa5f9d2229cc5f060e72e2859b78fa --- /dev/null +++ b/msigdb_reactome/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:12329debca75c5268d3e3318f6253567715f23766e065865770802eb30b8e70f +size 203683 diff --git a/msigdb_reactome/advanced/plot_3.png b/msigdb_reactome/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..eef20d7194586a8a5ad861b16708e5b486b54379 --- /dev/null +++ b/msigdb_reactome/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b1ac7a0926283cafb43f450ddf9e5c5037187f06f6e6746aeddc7f43fd40d662 +size 200925 diff --git a/msigdb_reactome/advanced/plot_4.png b/msigdb_reactome/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..7a5a9cf788838aa8f0eb28f85cd90b2b1fafd998 --- /dev/null +++ b/msigdb_reactome/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1a333b614587bc4499c99f4548b22477085ed3998052880b04a13df80735feb5 +size 203453 diff --git a/msigdb_reactome/advanced/plot_5.png b/msigdb_reactome/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..2936a59549d9798a61bb3837bb3f44f9de5e7e59 --- /dev/null +++ b/msigdb_reactome/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:15123fdf7a0455c3f014766278c5675526ad32b1def2ec5abaf490c43d084472 +size 197699 diff --git a/msigdb_reactome/advanced/plot_6.png b/msigdb_reactome/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..4fddce69a59a6256d1314d51d997aa0f674f1fc7 --- /dev/null +++ b/msigdb_reactome/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6a650b1ece1c30866e22c4007f1c3810cf696b3b67f6b2342ae20817b1d9b507 +size 204464 diff --git a/msigdb_reactome/advanced/plot_7.png b/msigdb_reactome/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..6609aa204a4b3e8de147e4a8643c2800a9f7d261 --- /dev/null +++ b/msigdb_reactome/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:021f2209eff0c4a7c890d0648a008692253ca92da2fc53886bc184674bbc9d38 +size 206499 diff --git a/msigdb_reactome/advanced/plot_8.png b/msigdb_reactome/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..555465245bd37471f1818eea23c52d25d573e354 --- /dev/null +++ b/msigdb_reactome/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fd98a6c0ad604dba96be96e45415891dff0b0b2790ae6654edbf69e888a7f4b5 +size 199240 diff --git a/msigdb_reactome/advanced/plot_9.png b/msigdb_reactome/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..2859336dd98e96cbea10d54727f2576d89a1b359 --- /dev/null +++ b/msigdb_reactome/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:33f35e199641af3f1aa1f9e5664c2c1aa70ab4ade854f3345d02a8284b065eb5 +size 208746 diff --git a/msigdb_reactome/basic/idx2term.json b/msigdb_reactome/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..7992903fe5f8e1696b146b5b97961bddac86fcfd --- /dev/null +++ b/msigdb_reactome/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Protein localization", "1": "Metabolism of lipids", "2": "Sphingolipid metabolism", "3": "Mitochondrial protein import", "4": "Glycosaminoglycan metabolism", "5": "Glycosphingolipid metabolism", "6": "Slc mediated transmembrane transport", "7": "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "8": "Mitochondrial calcium ion transport", "9": "Phospholipid metabolism", "10": "The citric acid tca cycle and respiratory electron transport", "11": "Respiratory electron transport", "12": "Sphingolipid de novo biosynthesis", "13": "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "14": "Peptide ligand binding receptors", "15": "Class a 1 rhodopsin like receptors", "16": "Glycerophospholipid biosynthesis", "17": "Gpcr ligand binding", "18": "Interactions of vpr with host cellular proteins", "19": "Slc transporter disorders", "20": "Transport of small molecules", "21": "Synthesis of pa", "22": "Complex i biogenesis", "23": "Peroxisomal protein import", "24": "Organelle biogenesis and maintenance", "25": "Class i peroxisomal membrane protein import", "26": "Ns1 mediated effects on host pathways", "27": "Selective autophagy", "28": "Autophagy", "29": "Metabolism of steroids", "30": "Sumoylation of rna binding proteins", "31": "Nuclear pore complex npc disassembly", "32": "Sumoylation of ubiquitinylation proteins", "33": "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "34": "Regulation of glucokinase by glucokinase regulatory protein", "35": "Mitochondrial biogenesis", "36": "Aurka activation by tpx2", "37": "Nuclear envelope breakdown", "38": "Recruitment of mitotic centrosome proteins and complexes", "39": "Biological oxidations", "40": "Neutrophil degranulation", "41": "Interleukin 4 and interleukin 13 signaling", "42": "Nuclear envelope ne reassembly", "43": "Sumoylation of sumoylation proteins", "44": "Export of viral ribonucleoproteins from nucleus", "45": "Cristae formation", "46": "Cholesterol biosynthesis", "47": "Activation of ampk downstream of nmdars", "48": "Gene silencing by rna", "49": "Recruitment of numa to mitotic centrosomes"} \ No newline at end of file diff --git a/msigdb_reactome/basic/plot_0.png b/msigdb_reactome/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..02a9f5530079c3ec68f3f6c2f7b76887fda00b0c --- /dev/null +++ b/msigdb_reactome/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:66284b43aa25f88fd497b87928903e192224898e5d0361f6cab87f803a1980e9 +size 141829 diff --git a/msigdb_reactome/basic/plot_1.png b/msigdb_reactome/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..038d445fbd45dcb4fdd22f8b58460cd3b99fbbb6 --- /dev/null +++ b/msigdb_reactome/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:51a0e8673562d180173a2e37286032dbe0f595b2c8c02ceb2edadecef6cde0fa +size 138524 diff --git a/msigdb_reactome/basic/plot_10.png b/msigdb_reactome/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..609bdf843a8e118d23d0c0b9e88ff9cc22e361b5 --- /dev/null +++ b/msigdb_reactome/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5d31ac6fa22b7fa3486b6608e02563c1b52af44b0183316769f5cc4b87bb83cc +size 153123 diff --git a/msigdb_reactome/basic/plot_11.png b/msigdb_reactome/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..67bfe6b704fbc2ef946a2c0b3d31cb1f798bf239 --- /dev/null +++ b/msigdb_reactome/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:47c3466eead4658369ef0e51d7a3e25ab6d76488f7236de29fed370f457b403f +size 148398 diff --git a/msigdb_reactome/basic/plot_12.png b/msigdb_reactome/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..db8a320b8aa1568c444d351ebc8fa0d7786e1e32 --- /dev/null +++ b/msigdb_reactome/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:940c172c4a549f1953d1bb6c9fb8fad45d912f59ea26539d21792bb41e45f138 +size 146448 diff --git a/msigdb_reactome/basic/plot_13.png b/msigdb_reactome/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..31a8f00d9570810ac0888bcd886e74eecf964c75 --- /dev/null +++ b/msigdb_reactome/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:521e59a142be369e25f43d79854b0bb1d7e0957eba78e2c12a1b45ab38d93dc0 +size 153588 diff --git a/msigdb_reactome/basic/plot_14.png b/msigdb_reactome/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..a7b89a710322018d436b9bb8b22cc9ad35802a7e --- /dev/null +++ b/msigdb_reactome/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9860d71097b233e389d3af0dfb0d05a6ae822252782bf14e4c97d69604ef045f +size 141930 diff --git a/msigdb_reactome/basic/plot_15.png b/msigdb_reactome/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..8d5522f71e1c50b8d1e7319770002a8040dd3eaf --- /dev/null +++ b/msigdb_reactome/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ab5b92b8b98d8c90019d90e37d12fd8ded5b6307edd9ca39d1d287a911dfd26 +size 143228 diff --git a/msigdb_reactome/basic/plot_16.png b/msigdb_reactome/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..1e7d830bcd48ab8faa7d3730e2208de92996bf0a --- /dev/null +++ b/msigdb_reactome/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0b19c56fc081bef643be82f976476f47c9acd3d988622e643867ddbee7a8b7f4 +size 146067 diff --git a/msigdb_reactome/basic/plot_17.png b/msigdb_reactome/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..df12b4c8feb1f07616c319209a601025466fbdbc --- /dev/null +++ b/msigdb_reactome/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41b8dd7df4df3823e91f101d036bb741d9caeea473d6457d8663118dc8b7ec75 +size 138009 diff --git a/msigdb_reactome/basic/plot_18.png b/msigdb_reactome/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..33d101542b2ea1f11635052731e2612733da1e3d --- /dev/null +++ b/msigdb_reactome/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6032b0d13152b5f97601b495d949ed47ba821df82ae08af41e0d44a147de2534 +size 143842 diff --git a/msigdb_reactome/basic/plot_19.png b/msigdb_reactome/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..74b335579252e6840877d5ef7e58ca683be38fb7 --- /dev/null +++ b/msigdb_reactome/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:84047bae6cc434291d97539871781758488cc63f732bd76c636e9054e4226864 +size 139544 diff --git a/msigdb_reactome/basic/plot_2.png b/msigdb_reactome/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..9bb33df7605d640127db9a2684539e7ff79247dd --- /dev/null +++ b/msigdb_reactome/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:79ba969022ce72703bbe919ddab2c0d85fd632518be937d3ae6bd9a9b6c548fc +size 146899 diff --git a/msigdb_reactome/basic/plot_20.png b/msigdb_reactome/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..492dd8b83e6c389338a41e50640356591934b140 --- /dev/null +++ b/msigdb_reactome/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:929f7be8cac02d6cf74f6bca1c1cda164a2a7df1d56d753cb243e1ef05d21c80 +size 144291 diff --git a/msigdb_reactome/basic/plot_21.png b/msigdb_reactome/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..535de49f607c7fe1b54bbea1dbe1b427ae192825 --- /dev/null +++ b/msigdb_reactome/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b402ae2ed9943202d956bbfd0c00b3afd30f10790a4af0f5696c0d6eebd53cf2 +size 133626 diff --git a/msigdb_reactome/basic/plot_22.png b/msigdb_reactome/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..2363d1ae514c3b68237a9b0ca9463c28335e4fea --- /dev/null +++ b/msigdb_reactome/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6950087265c90ee28fb519d3361fdf1397d947f9a38c115bc2c18fc7b1120c2f +size 142314 diff --git a/msigdb_reactome/basic/plot_23.png b/msigdb_reactome/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..f54352e5ff6f63bded438403d6e12186aaf25897 --- /dev/null +++ b/msigdb_reactome/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:50fa1851d6346e65058e5422cd16e42d5e5706db8969bacf3ef11b6d3b966e41 +size 133562 diff --git a/msigdb_reactome/basic/plot_24.png b/msigdb_reactome/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..52f51ac0b4bd840719d5a907eac1047a6394dfb0 --- /dev/null +++ b/msigdb_reactome/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5b8e21d7e9e2c528dc56873b7aef79665e95b15c7efaa05b80b086712a3e7057 +size 149778 diff --git a/msigdb_reactome/basic/plot_25.png b/msigdb_reactome/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..5c9caaf45deb9ce4bd3976c43e00050981733476 --- /dev/null +++ b/msigdb_reactome/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ceaec7389678f62a299fd2c18581bef2b081575376a82a8ce2366f8357dee748 +size 139653 diff --git a/msigdb_reactome/basic/plot_26.png b/msigdb_reactome/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..8d47dfc26192f833892f9305df8861849d4305c8 --- /dev/null +++ b/msigdb_reactome/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90c1c17975f25a1a70dfd7c281232e952e084ec568f39074ff7e7dc9bd15eaca +size 149487 diff --git a/msigdb_reactome/basic/plot_27.png b/msigdb_reactome/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..0563f5a0d0211762f654ea462faee2ffcbe64e56 --- /dev/null +++ b/msigdb_reactome/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90131b0b3cc42cfc437e0eb86baf32198487a47e9923d2561903ffa2767cbb50 +size 139145 diff --git a/msigdb_reactome/basic/plot_28.png b/msigdb_reactome/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..312a5756e2b385f72ff148771e388cf942e1611e --- /dev/null +++ b/msigdb_reactome/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:76ff63de4b6ddabfcc7aca3d6705a7f65648b922e69bc0b6f89820ebb2e2243f +size 138147 diff --git a/msigdb_reactome/basic/plot_29.png b/msigdb_reactome/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..210d72e5ef0b803133e1fc796e64fc52961cbb1e --- /dev/null +++ b/msigdb_reactome/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0893dcba586638a9a999159f1dd5180f57a1f40cdae8b00c37c8151f5f9b233f +size 140194 diff --git a/msigdb_reactome/basic/plot_3.png b/msigdb_reactome/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..19d562ada2420e699e0d3f23436659c9ec5b4176 --- /dev/null +++ b/msigdb_reactome/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f52899ae22da23e1270f13bf2c8045183211ef165dfeb5934b958e64b2d2fd7c +size 140578 diff --git a/msigdb_reactome/basic/plot_30.png b/msigdb_reactome/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..a37c0231e26efcda26310c02344a087980cf9c1c --- /dev/null +++ b/msigdb_reactome/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:abe4fd79eabc818d668bbf582068b75b94e8c173082501d7cced282dd68058d4 +size 146560 diff --git a/msigdb_reactome/basic/plot_31.png b/msigdb_reactome/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..31925a62a24c0b2edcfb8237f4b255cd17f819f5 --- /dev/null +++ b/msigdb_reactome/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:abe01404924f4e5fee72d1bd1d61dc9c7ff4544b3554e39ab2b1327615c6625e +size 149439 diff --git a/msigdb_reactome/basic/plot_32.png b/msigdb_reactome/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..9f91fb449998c6cc14070a83352d1e55e271fc53 --- /dev/null +++ b/msigdb_reactome/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6dee1f8023d8884a1623c6960c4d7e7dc5f1964abb288015c77bbd6cdbf36945 +size 141224 diff --git a/msigdb_reactome/basic/plot_33.png b/msigdb_reactome/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..1f4a30e8014d5863375cfe1b233b782f0fe92e49 --- /dev/null +++ b/msigdb_reactome/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d68c3142df4b535315d3e75bb896bce67d3869707ba98b122fcd5018999a2400 +size 137181 diff --git a/msigdb_reactome/basic/plot_34.png b/msigdb_reactome/basic/plot_34.png new file mode 100644 index 0000000000000000000000000000000000000000..0695d445701e6f0560b85ec48da5c6d5df848684 --- /dev/null +++ b/msigdb_reactome/basic/plot_34.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:062e259368263b5450ca6924ec9089bb6471a0ce61e1681cea1c6057bbb58ef4 +size 138254 diff --git a/msigdb_reactome/basic/plot_35.png b/msigdb_reactome/basic/plot_35.png new file mode 100644 index 0000000000000000000000000000000000000000..cb69b9867d1b7824c519ba76a4289e73812a59c7 --- /dev/null +++ b/msigdb_reactome/basic/plot_35.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e6b8fbfe5cb29a2e06cfaa56ed0ab96602d7aef909531bdd34ea4c7e82706ad1 +size 143165 diff --git a/msigdb_reactome/basic/plot_36.png b/msigdb_reactome/basic/plot_36.png new file mode 100644 index 0000000000000000000000000000000000000000..8dac95c7ddc2f780ba3060b4268acb7cf38f2065 --- /dev/null +++ b/msigdb_reactome/basic/plot_36.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ad83e482d212c246a6ac66be0c2d231c1bec1dade176ce1282a4e188d321051 +size 142461 diff --git a/msigdb_reactome/basic/plot_37.png b/msigdb_reactome/basic/plot_37.png new file mode 100644 index 0000000000000000000000000000000000000000..ae2c4bd8c8daaa8edd8ea605d2a36b2e9c7078ff --- /dev/null +++ b/msigdb_reactome/basic/plot_37.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:93dfd033db837a1c5bc44144c03c55b7503d22bc4155349fb7748350e19d18d5 +size 145915 diff --git a/msigdb_reactome/basic/plot_38.png b/msigdb_reactome/basic/plot_38.png new file mode 100644 index 0000000000000000000000000000000000000000..2f9076b2d9946b01e25c3058f01cf21a9b843973 --- /dev/null +++ b/msigdb_reactome/basic/plot_38.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7b8512166d7fd7cd9b14a3f9c7b0ae7a83bb2c763b77191106353bbd6d5301ce +size 148129 diff --git a/msigdb_reactome/basic/plot_39.png b/msigdb_reactome/basic/plot_39.png new file mode 100644 index 0000000000000000000000000000000000000000..c47e7d7087d409b8cdcc106b451ba3cd0a778ce8 --- /dev/null +++ b/msigdb_reactome/basic/plot_39.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6b3944ea628e32276bdf3231b897f71c2490a253116080f3f1904f7d555a5d53 +size 138340 diff --git a/msigdb_reactome/basic/plot_4.png b/msigdb_reactome/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..8679953fa1abe4351e74fa46a2b7183aa46f7078 --- /dev/null +++ b/msigdb_reactome/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:63cfae80381ebd41b428c32857aef373f17e88c8386604e11a06fcc7ffca55d3 +size 146223 diff --git a/msigdb_reactome/basic/plot_40.png b/msigdb_reactome/basic/plot_40.png new file mode 100644 index 0000000000000000000000000000000000000000..754cabdc0f270bf56cb1c820b7d3dccd80f6ac9e --- /dev/null +++ b/msigdb_reactome/basic/plot_40.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:73708368a4e43ea6172e5b91c364b6f4aa447a254f7083ea67b466919a8d4c90 +size 144487 diff --git a/msigdb_reactome/basic/plot_41.png b/msigdb_reactome/basic/plot_41.png new file mode 100644 index 0000000000000000000000000000000000000000..f581a468ab67a01e73f999a7c48499572cd7eb50 --- /dev/null +++ b/msigdb_reactome/basic/plot_41.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:600d7b3e2b3ed16e11c846bcd00dd03c9ceb6b34c9e3920c48d76a7fc1b4bc1d +size 140362 diff --git a/msigdb_reactome/basic/plot_42.png b/msigdb_reactome/basic/plot_42.png new file mode 100644 index 0000000000000000000000000000000000000000..1111b70f1fb13dde3dda51aee50ad87d15cb8dee --- /dev/null +++ b/msigdb_reactome/basic/plot_42.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba334a1c8d517737c8f396ff8c74b58e5727b3cb2fa6161fa6410e3312d22530 +size 147935 diff --git a/msigdb_reactome/basic/plot_43.png b/msigdb_reactome/basic/plot_43.png new file mode 100644 index 0000000000000000000000000000000000000000..365fa0a915c143bc8e09b7854913ddaafd717937 --- /dev/null +++ b/msigdb_reactome/basic/plot_43.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fd814b81c5fdd83b2a3fd4dc1320be449178069d12b0a5bde7dc32aa0586a145 +size 147086 diff --git a/msigdb_reactome/basic/plot_44.png b/msigdb_reactome/basic/plot_44.png new file mode 100644 index 0000000000000000000000000000000000000000..bae35bf539e9bf670b1df45e9df6ab9463b4b535 --- /dev/null +++ b/msigdb_reactome/basic/plot_44.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:42eb1e26b4fece36c54ff0bfeb6f920d0588373e8d1f9b0b1342610d18a623b5 +size 148312 diff --git a/msigdb_reactome/basic/plot_45.png b/msigdb_reactome/basic/plot_45.png new file mode 100644 index 0000000000000000000000000000000000000000..d32e9f70a9ebb4416a1b0f31b17a86cb2d2c2c05 --- /dev/null +++ b/msigdb_reactome/basic/plot_45.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:80d9bbff7732b2244deba04e60d0abe86b253c99e2e555d6a9ce8916c39f0b6d +size 130549 diff --git a/msigdb_reactome/basic/plot_46.png b/msigdb_reactome/basic/plot_46.png new file mode 100644 index 0000000000000000000000000000000000000000..8af192bfcfb7356cb45cb3e269d7e9f870115d40 --- /dev/null +++ b/msigdb_reactome/basic/plot_46.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:42934b932164e78b0faaf24f6f94f9b56fc69f9d6152c150aa3eff43c9fa044c +size 136939 diff --git a/msigdb_reactome/basic/plot_47.png b/msigdb_reactome/basic/plot_47.png new file mode 100644 index 0000000000000000000000000000000000000000..c0eef17dde1e278bb0aaabdf62b50fe04edf981f --- /dev/null +++ b/msigdb_reactome/basic/plot_47.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0081d3472edcce1d964b49ff34774b9a01f14f5f5b513925c0149e16a918ce3c +size 135156 diff --git a/msigdb_reactome/basic/plot_48.png b/msigdb_reactome/basic/plot_48.png new file mode 100644 index 0000000000000000000000000000000000000000..ab536845477facc16fbc044fa195900d0b0175e2 --- /dev/null +++ b/msigdb_reactome/basic/plot_48.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:034deb920b33c08fa17e36e9e542ba57e95914996aab60b09056cd602fa342b7 +size 142711 diff --git a/msigdb_reactome/basic/plot_49.png b/msigdb_reactome/basic/plot_49.png new file mode 100644 index 0000000000000000000000000000000000000000..cb8b69025336bd9cad028ed884fe800eb86e2764 --- /dev/null +++ b/msigdb_reactome/basic/plot_49.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9bd714c0469daaf9d1b737d418c21ea6371f492b0d526d154f040dd9b435ad79 +size 147529 diff --git a/msigdb_reactome/basic/plot_5.png b/msigdb_reactome/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..6ae2dd6eac774b29c62991c4d2c75ccbbcc5adba --- /dev/null +++ b/msigdb_reactome/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6d7b5825d5ca46715f2de81c3435447cb1dda3de83d6a089c440c044d0fa299e +size 145946 diff --git a/msigdb_reactome/basic/plot_6.png b/msigdb_reactome/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..6017fee056ec63cc057412eef2442f8458c0f947 --- /dev/null +++ b/msigdb_reactome/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:63c65f266bf2adf10949721a8ce7bf37fa71243977bd8c0ac6e1703a3d445afb +size 144603 diff --git a/msigdb_reactome/basic/plot_7.png b/msigdb_reactome/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..e41b16d800309b9f68c643e6a738f875c6d59500 --- /dev/null +++ b/msigdb_reactome/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d88a852fc0e36f58bffddc52584bcf3ff677b895223ccbc8ce421c084295e737 +size 145176 diff --git a/msigdb_reactome/basic/plot_8.png b/msigdb_reactome/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..f6065ad71a558f84353eeac04b5cf191afc499d0 --- /dev/null +++ b/msigdb_reactome/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:dc92688b8a75f4a6f3859ae667a55805e4cfa51b3657a24b181c7b65bceadb7d +size 142651 diff --git a/msigdb_reactome/basic/plot_9.png b/msigdb_reactome/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..1b59aae14e84c5f17c69488425d8c5c0212d8f19 --- /dev/null +++ b/msigdb_reactome/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d2aa29fa7d80d96778ffae703ce5c8f598bf5e626413668cebca188711c170ab +size 141022 diff --git a/msigdb_reactome/consensus.joblib b/msigdb_reactome/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..a2700ad4e4b565cd120c68cf0546721550862ec8 --- /dev/null +++ b/msigdb_reactome/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:90910252de5c6be4a6b3964930cce0cb12b93babfefa2de3a811398e850de216 +size 231683 diff --git a/msigdb_reactome/df_merge.tsv b/msigdb_reactome/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e8ffc38fecc450cbf821775903e59caea313ddc8 --- /dev/null +++ b/msigdb_reactome/df_merge.tsv @@ -0,0 +1,30 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Protein localization 36 77 5.0317728872666105 4.859647573909643e-07 25.97087378640777 74.18203883495146 1.5594110758345356 0.2555609300308859 10.717199959161563 6.26233677332747 2.0947329132902324 0.3569924888492793 1.3766678784152692e-08 0.0050563691544293 7.348969636463593e-05 5.989624079307199e-08 9.581629487723108e-13 +Metabolism of lipids 76 200 4.146631303911766 3.374027218749909e-05 47.21601941747573 182.9902912621359 0.7669400545274999 0.4573741022352977 16.76057659641467 20.451455734561765 1.5920609507025254 0.4091924181498379 7.406488598315743e-08 0.0030351901549339 0.0004129955105105 1.694481475935345e-05 9.273659696617255e-11 +Sphingolipid metabolism 16 26 3.983344164395988 6.795223617572788e-05 11.00242718446602 26.135922330097088 1.1708540815039898 0.1757583754913391 4.192861933829232 2.1968580551223003 2.1941615995620167 0.2567064655985949 1.11987551402712e-07 0.0034245890280422 0.00034111574813 0.0001222791367212 3.524067922589048e-09 +Mitochondrial protein import 14 36 3.781716230194339 0.0001557508500289 13.468446601941748 34.5873786407767 1.6025718162972953 0.1874419874946837 6.078090089851624 2.2108812815475147 1.8878681708577505 0.2901223460226844 6.19471286664356e-09 0.0029741493546945 2.2653824984110297e-05 1.397501163165616e-08 1.2184124556378644e-08 +Glycosaminoglycan metabolism 9 15 3.273231599060609 0.0010632531778991 6.563106796116505 14.388349514563108 0.750167459040055 0.1742505874253542 2.387954817808654 2.3973407990867264 1.8682770414846892 0.2409021330213527 0.0001338721998496 0.046072228335376 0.0005997641678419 0.0015399081103358 0.001939589155648 +Glycosphingolipid metabolism 9 16 2.9750984203523823 0.002928945598049 7.514563106796117 15.521844660194176 0.6340330218232789 0.1371235236408302 2.3948329397108954 1.2175929202976112 2.2116324239586063 0.2290247571497847 2.553364473926763e-06 0.0005458668398673 0.0002865257018003 0.0011317572349641 2.279269041182348e-06 +Slc mediated transmembrane transport 12 20 2.9559861549767024 0.003116710811446 8.672330097087379 21.910194174757283 1.4735742044813558 0.239038892478899 4.348519601656105 3.146764860695784 1.3934177975338422 0.3068823132077037 0.0228801367862345 0.0876325329480415 0.0767446240128207 0.1008932065693596 0.0569169902542498 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 7 18 2.884130567705939 0.003924959806661 6.014563106796117 17.274271844660195 0.870961683103299 0.329566970411291 2.8591161566949044 2.4465188670593117 1.2657234914365352 0.3108311955329007 0.0708436887768242 1.0 1.0 0.1564032996109324 0.0181935817738085 +Mitochondrial calcium ion transport 6 15 2.8753814426043927 0.0040353966240684 6.502427184466019 16.12135922330097 1.0650233237312683 0.2089377868120644 3.410790121717641 1.246287729205551 1.626144580445205 0.28031724173526 0.1155282698604689 0.0046633751497463 0.0177148463510605 0.0920739634299925 0.0003730251283681 +Phospholipid metabolism 16 49 2.8621899088685963 0.0042072473041672 12.859223300970871 45.932038834951456 1.017004520648936 0.3949296504793965 6.241466981115118 7.362344677079641 1.3242274243570669 0.3709328103546776 0.071169986501166 1.0 0.4543693785750186 0.0876606583358337 0.0197047982671626 +The citric acid tca cycle and respiratory electron transport 27 98 2.8215190973399555 0.0047796791596168 27.99757281553398 94.17961165048544 0.4883573568636233 0.4259472248586306 12.60942373482268 7.020896123249261 1.7895370613076145 0.38969273744301 4.0414969886161153e-05 0.0001220824318871 0.0001690733465498 0.0001455215471668 2.0050212604931408e-07 +Respiratory electron transport 17 54 2.7968828004723565 0.0051598246511685 17.473300970873787 52.5752427184466 0.7619430018929745 0.3962973483509951 7.757662405441163 5.39117119769307 1.7039672197087123 0.3858226471737118 0.0072310416875811 0.0132057985495328 0.0030917023376328 0.003234596157693 2.671732266324261e-05 +Sphingolipid de novo biosynthesis 7 10 2.7182263469029686 0.0065632922188421 4.08252427184466 10.614077669902912 1.3205451179619188 0.2079933246203462 1.939118365602947 1.3614298144224892 1.289169434780902 0.261809046515659 0.0081826700022156 1.0 0.2489059409173845 0.0329460998536745 0.000378511976274 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 25 63 2.629084532335111 0.0085615076061595 20.8373786407767 62.38106796116505 0.8350130317954786 0.3584533980641267 8.974357262450994 5.887120286458052 1.9056004199022172 0.3784220720284639 0.0014912161298487 0.0024477331896819 0.0009521568682065 0.0005310967041711 1.1385091929665135e-05 +Peptide ligand binding receptors 5 7 2.6043192976440688 0.0092056950375385 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0010667446002337 0.0802348466038066 0.0117676307173903 0.0006430769062578 0.0001004910149917 +Class a 1 rhodopsin like receptors 5 7 2.6043192976440688 0.0092056950375385 2.8640776699029127 6.796116504854369 1.193322814833652 0.1851946070449122 1.2850789986620814 0.7987760455175396 1.3206182868906609 0.2426624676455473 0.0024564584457719 0.0981765691424607 0.0177148463510605 0.0014975917181939 0.0003730251283681 +Glycerophospholipid biosynthesis 13 30 2.603392249703823 0.0092306277747897 9.439320388349516 29.58009708737864 1.1800609247564997 0.3081196451067344 4.809346434845489 4.094857299253986 1.3402414818469337 0.3224557628717913 0.0101452461427695 1.0 0.2063668513530253 0.018497294766084 0.0008792700286468 +Gpcr ligand binding 5 10 2.60232710265528 0.0092593490405537 3.4611650485436893 9.330097087378642 1.051447004644797 0.2131328881138611 1.5951828582954857 1.3192992367203638 1.3003237502897853 0.2397874119507845 0.0389400516653052 0.2027885470531376 0.0746250944081647 0.0254140783095469 0.0230912453221162 +Interactions of vpr with host cellular proteins 14 30 2.4981913346547016 0.012482879842022 10.941747572815531 33.44174757281554 -0.2027749306543701 0.6500206570215948 5.4248175535845045 1.1901720746801605 0.9115358979979576 0.3218663131177026 0.0191264760349916 0.1665759675679584 0.0507931717892238 0.0121856638082503 0.0082637154660588 +Mitophagy 2 12 2.4913313296570245 0.0127265377651732 3.662621359223301 11.783980582524272 1.3564301304992197 0.1917930287367771 1.8155907654273165 1.3363606860118669 1.2723890100166135 0.2636913304405313 0.0283422290577001 0.0060718409625537 0.0228441699597423 0.0199432580741765 0.1088149775417643 +Pink1 prkn mediated mitophagy 2 8 2.439795883948056 0.014695562664966 3.2815533980582523 8.473300970873787 1.395617281862234 0.1554977461962819 1.6230588150315317 0.9738153254376878 1.3577427922485954 0.2414588001366878 0.0109888256406173 0.0030581061915538 0.0117676307173903 0.0075942890928168 0.0468003866103798 +Slc transporter disorders 13 29 2.387068856057935 0.0169833100714857 10.072815533980584 32.68689320388349 0.1121793221691444 0.6146102245245559 5.627130779592072 1.491569531804079 1.0244067182438623 0.3378443700099887 0.0636388778287945 0.2336798458054532 0.0981876870196897 0.3814690602891797 0.1208874805839759 +Transport of small molecules 47 154 2.3758058182968207 0.0175106751677489 41.730582524271846 151.96601941747574 1.4265613612661356 0.380396759556163 14.87709311863932 12.598305121005488 1.746958952072276 0.4128488770716938 0.0001432235998827 0.0022625939925988 0.0115522492373134 0.0009230197041373 3.4775385917067025e-05 +Heparan sulfate heparin hs gag metabolism 4 5 2.3035854032147776 0.021245928012942 2.4320388349514563 4.83252427184466 0.8003221575390526 0.2230961855611341 1.2648123228701085 1.2708877857521428 1.4628061886044337 0.2633127679646707 0.0116058691176623 0.1457663642848915 0.0390334649397651 0.0424141111811751 0.0181161163925661 +Synthesis of pa 6 12 2.2566141739668915 0.024032193918192 2.9635922330097086 8.558252427184467 0.9129149199765416 0.2964837496518883 1.9473992387004595 1.904008254033093 1.1909456358572703 0.2923824193190221 0.0315585289040891 1.0 0.2186221342412543 0.0222629680099487 0.0063149437065281 +Complex i biogenesis 13 30 2.21714562730946 0.0266131417215502 9.1747572815534 28.546116504854368 0.5440760559261008 0.4236381582634617 4.289696810672699 3.852285850983641 1.2631239118061712 0.3404380044043241 0.0197042635512613 0.0306743412959273 0.0174347284732116 0.0115741629942865 0.000319988503031 +Keratan sulfate keratin metabolism 3 6 2.189661640443015 0.0285487850147392 3.1359223300970873 5.439320388349515 0.1148000450757159 0.1857420338858874 1.294488268568909 0.7592200419566036 1.8452752770630356 0.2520366769461069 0.0010667446002337 0.0030581061915538 0.0117676307173903 0.0075942890928168 0.0079370796506279 +Peroxisomal protein import 7 24 2.1183345003728427 0.0341467487569988 5.509708737864078 20.961165048543688 -0.2101406023902152 0.4556646045130463 2.6979681158237065 3.026332106908075 1.071934776270471 0.2891517244312681 0.7653053520781201 0.2222355866483168 0.3958350013250431 0.7175036707273205 0.0029760556157756 +Organelle biogenesis and maintenance 40 104 2.079488449230864 0.0375724783766897 25.364077669902912 93.59466019417476 0.8635708484684039 0.4952956395971041 8.486338013959335 9.495950625534562 1.0729913690397648 0.3929655478972317 0.217743886594428 0.3799377951400663 0.1230036620674163 0.3320209816651341 0.0637920437213331 diff --git a/msigdb_reactome/metrics.json b/msigdb_reactome/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..72b5f89b894e9ea6f023eb1710a7c0d0ab09e845 --- /dev/null +++ b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 1411, + "title": "Average number of proteins per term", + "value": 20.250177179305457 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..fe5fcda2e9e714bac8500094ecf7fc8c9ff2e597 --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a73e2fd7ccd66c1caecb94b0697f9af011c7086e --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,367 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protein localization 0.6085371915377237 5.0317728872666105 4.859647573909643e-07 0.000685461403213 0.00068569627268 77 P46379,O75874,Q8TB36,Q9NS69,P21796,O14734,O60830,Q9Y512,O15254,Q13190,P12236,Q10713,O14975,P08574,P50402,P28288,O15228,O43681,Q9Y5J7,Q13505,P09601,O43615,Q15067,Q2T9J0,Q9Y5J9,O14925,P05067,Q99595,Q5JRX3,P12235,A8MXV4,Q8N4H5,P51648,Q9Y584,Q9NR77,Q9Y5L4 36 +Metabolism of lipids 0.4211312868129785 4.146631303911766 3.374027218749909e-05 0.0464928232439221 0.0142170930926621 200 P30536,Q06136,O76062,Q53GQ0,Q8NAN2,Q9NP80,P38435,Q15165,O14734,O00767,Q8WVX9,Q06520,P06865,P06280,P50897,Q15392,Q96K12,Q14849,O15254,P04062,P23786,O15269,Q8N2A8,Q10713,P07602,P37268,Q9P035,O14975,Q96SU4,P16278,O15270,Q9BWD1,P43304,O95864,O43681,O15228,Q96N66,P22059,Q15067,Q6IAN0,P17900,O43808,Q9BZF1,Q709F0,P54646,Q9BTU6,Q9NXE4,Q9NZJ7,Q99519,Q16850,O75845,O95470,Q9H7Z7,Q15800,O43772,Q8NCC3,Q9NPH0,Q14739,A8MXV4,Q9UG56,P10619,Q14534,P48651,Q13510,Q9NUQ2,P51648,Q9UBM7,Q8NF37,Q8TBX8,P27544,Q8IV08,O95487,Q16836,P35610,Q96G23,Q9NZ01 76 +Sphingolipid metabolism 0.7856135844384672 3.983344164395988 6.795223617572788e-05 0.0914304715574664 0.0142170930926621 26 Q06136,O15269,P17900,P10619,P07602,O15270,P16278,P51648,Q9NZJ7,P06865,P06280,O95470,Q13510,P22059,Q96G23,P04062 16 +Mitochondrial protein import 0.6535138382044339 3.781716230194339 0.0001557508500289 0.1973058850323827 0.0142170930926621 36 Q9Y5J9,Q10713,Q8N4H5,Q9NS69,P21796,O14925,Q99595,O60830,Q9Y512,Q5JRX3,Q9Y584,P12235,Q13505,Q9Y5L4 14 +Glycosaminoglycan metabolism 0.8405556635226923 3.273231599060609 0.0010632531778991 0.7771036408498495 0.0277824117410308 15 Q7LGA3,P16278,P15586,Q9UL01,P06865,O60512,P54802,Q8TB61,P08236 9 +Abacavir transport and metabolism 0.9533255542590428 3.205466865912767 0.0013484357066517 0.8510175450768622 0.0292186751122573 2 P49902 1 +Synthesis of pg 0.9524504084014012 3.2015900776514634 0.0013667133645705 0.8548157373800304 0.0292186751122573 2 Q8IV08 1 +Proton coupled monocarboxylate transport 0.920361726954492 3.0581960839204103 0.0022267381922691 0.9569516301818284 0.0383161901133143 2 P53985 1 +Neurotransmitter clearance 0.9177362893815636 3.046355403686171 0.0023163386097697 0.9620750070996924 0.0393777563660859 2 P05091 1 +Glycosphingolipid metabolism 0.7668131694717759 2.9750984203523823 0.002928945598049 0.9840581311761196 0.0472118855526876 16 P10619,P17900,P07602,P16278,Q9NZJ7,P06865,P06280,Q13510,P04062 9 +Slc mediated transmembrane transport 0.6941656265903572 2.9559861549767024 0.003116710811446 0.987778350792024 0.0477272333201705 20 P12236,P55011,P11166,Q9UBX3,Q70HW3,P53985,P35613,P30825,Q8TB61,P12235,Q9Y6M7,Q15043 12 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.7117132694094198 2.884130567705939 0.003924959806661 0.996108712720166 0.0553811828719878 18 O43852,O76024,Q9BTY2,P14625,P05067,Q02818,Q07065 7 +Mitochondrial calcium ion transport 0.7686774639584761 2.8753814426043927 0.0040353966240684 0.9966722680409866 0.0563736259416818 15 Q10713,P21796,P45880,Q9Y277,O95202,Q8IYU8 6 +Phospholipid metabolism 0.4835381110986897 2.8621899088685963 0.0042072473041672 0.9973914195379032 0.0570810187132686 49 Q9UG56,Q8N2A8,Q10713,Q9BZF1,Q8NAN2,Q9NP80,P48651,Q8NCC3,Q9NUQ2,P43304,O15228,Q8TBX8,Q8IV08,Q8NF37,Q96N66,Q9NPH0 16 +The citric acid tca cycle and respiratory electron transport 0.4076637743728955 2.8215190973399555 0.0047796791596168 0.9988411141605384 0.0608200100045354 98 P51970,Q15120,P11177,P21796,P48735,P24539,P53985,O95168,Q13423,P35613,O43676,O14949,Q9BQ95,P00403,Q9P0J0,O75306,Q86Y39,P08574,O75964,Q9Y6M9,Q9NPL8,P03886,Q9UDW1,Q15118,P13073,Q7L592,P14854 27 +Respiratory electron transport 0.4723207870098618 2.7968828004723565 0.0051598246511685 0.9993240290996293 0.0644293148920256 54 O75306,P51970,Q9Y6M9,Q9NPL8,Q86Y39,P03886,P08574,Q9UDW1,P14854,O95168,P13073,O43676,Q7L592,O14949,Q9BQ95,P00403,Q9P0J0 17 +Heme degradation 0.9420934229657028 2.740216241334276 0.0061398773755145 0.9998317521469884 0.0695548696556078 3 P30519 1 +Sphingolipid de novo biosynthesis 0.8317239466588915 2.7182263469029686 0.0065632922188421 0.9999077796411412 0.0729197269353245 10 Q06136,O15269,O15270,P51648,O95470,P22059,Q96G23 7 +Formyl peptide receptors bind formyl peptides and many other ligands 0.93270193484933 2.700202836200541 0.0069297212778589 0.9999452028787098 0.0752141286389153 3 P04083 1 +Transport of bile salts and organic acids metal ions and amine compounds 0.9206302888824052 2.648499989765556 0.0080849851686559 0.9999893960137376 0.0826895031406409 3 P53985,Q15043 2 +Ptk6 regulates proteins involved in rna processing 0.829929988331391 2.640585398002173 0.0082762931609194 0.9999919226168252 0.0826895031406409 2 Q07666 1 +Hs gag degradation 0.9177122847971908 2.6359563865140023 0.0083900514517198 0.9999931297109124 0.0826895031406409 3 P16278,P54802 2 +Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.4482213580396543 2.629084532335111 0.0085615076061595 0.99999461717396 0.0826895031406409 63 P51970,P24539,O95168,Q16134,O43676,O14949,Q9BQ95,P00403,Q9P0J0,O75306,Q86Y39,P08574,O75438,P06576,O75964,P21912,Q9Y6M9,Q9NPL8,P03886,Q9UDW1,P13073,Q7L592,P56385,O96000,P14854 25 +Noncanonical activation of notch3 0.8223453908984875 2.604626387088991 0.0091974492016391 0.999997823189263 0.0826895031406409 2 P67809 1 +Peptide ligand binding receptors 0.8970800149629127 2.6043192976440688 0.0092056950375385 0.9999978486018932 0.0826895031406409 7 P42892,P07602,P05067,Q9NZJ7,P04083 5 +Class a 1 rhodopsin like receptors 0.8970800149629127 2.6043192976440688 0.0092056950375385 0.9999978486018932 0.0826895031406409 7 P42892,P07602,P05067,Q9NZJ7,P04083 5 +Glycerophospholipid biosynthesis 0.5495690579896119 2.603392249703823 0.0092306277747897 0.9999979236521526 0.0826895031406409 30 Q9UG56,Q8N2A8,Q9BZF1,Q8NAN2,Q9NP80,P48651,Q8NCC3,Q9NUQ2,O15228,Q8IV08,Q8NF37,Q96N66,Q9NPH0 13 +Gpcr ligand binding 0.8086841119100806 2.6023271026552797 0.0092593490405537 0.9999980068692452 0.0826895031406409 10 P07602,P42892,P05067,Q9NZJ7,P04083 5 +Creb phosphorylation 0.8159276546091014 2.574084676755129 0.0100505672205344 0.999999354407146 0.0861342347295436 2 Q15418 1 +Downregulation of erbb4 signaling 0.8030921820303207 2.512684599159833 0.0119816401395624 0.9999999589383796 0.0913842931725549 2 P46934 1 +Interactions of vpr with host cellular proteins 0.53699827491174 2.4981913346547016 0.012482879842022 0.9999999799332092 0.0925539961276458 30 P12236,Q92621,Q12769,Q7Z3B4,Q99567,Q8NFH4,Q8N1F7,P05141,P49792,P52294,Q5SRE5,Q9BTX1,P35658,P12235 14 +Mitophagy 0.752941128356805 2.4913313296570245 0.0127265377651732 0.9999999858335558 0.0926670235505909 12 P21796,Q9NS69 2 +Pink1 prkn mediated mitophagy 0.8084472898580329 2.4397958839480554 0.014695562664966 0.9999999991529892 0.0987401853346054 8 P21796,Q9NS69 2 +Ubiquinol biosynthesis 0.7841306884480743 2.4212057184752713 0.0154691203307182 0.9999999997203582 0.1017997707984698 2 Q5T2R2 1 +Diseases associated with glycosaminoglycan metabolism 0.8682069723207932 2.420414161715358 0.015502838943056 0.9999999997335508 0.1017997707984698 3 P06865 1 +Intrinsic pathway of fibrin clot formation 0.7832555425904149 2.4169613098668146 0.0156506805779468 0.9999999997844315 0.1017997707984698 2 P42785 1 +Formation of fibrin clot clotting cascade 0.7832555425904149 2.4169613098668146 0.0156506805779468 0.9999999997844315 0.1017997707984698 2 P42785 1 +Cytochrome p450 arranged by substrate type 0.8666974315161089 2.413760384095346 0.0157888419066611 0.9999999998231646 0.1017997707984698 3 Q16850 1 +Abc transporters in lipid homeostasis 0.7823803967327918 2.412714933666789 0.0158341984282328 0.9999999998342975 0.1017997707984698 2 P28288 1 +Slc transporter disorders 0.533670136896738 2.387068856057935 0.0169833100714857 0.9999999999681274 0.1060329668622409 29 Q92621,Q12769,P11166,Q7Z3B4,Q99567,Q8NFH4,P53985,P35613,P49792,Q5SRE5,Q9BTX1,P35658,Q8N1F7 13 +Transport of small molecules 0.3545522757195748 2.3758058182968207 0.0175106751677489 0.999999999985052 0.1078932867322872 154 Q99623,P20020,P61916,Q9UBV2,P21796,P51798,Q9UBX3,P49721,P45880,Q70HW3,P16615,P35613,P53985,P30825,O95202,Q9H0U3,Q9C0H2,Q9Y6M7,P08183,Q99797,Q9HD20,Q4KMQ2,Q10713,P12236,Q9BU23,Q8WTV0,P30519,Q9Y487,P28288,Q9Y277,P20618,Q8TB61,P09601,O75477,Q15043,P55011,P28072,Q96PU5,P12235,Q13438,Q93050,Q8IYU8,Q15904,Q9BUN8,O15118,P35610,Q9NUT2 47 +Vitamin d calciferol metabolism 0.8548564810006662 2.361400654577359 0.0182060491988635 0.9999999999944956 0.1098765584655206 3 P04062 1 +Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.7686697782963843 2.345931711440021 0.0189795844812736 0.9999999999981898 0.1125218222818368 2 O00767 1 +Heparan sulfate heparin hs gag metabolism 0.903065693430646 2.3035854032147776 0.021245928012942 0.9999999999999308 0.1243900598600048 5 Q7LGA3,P16278,P08236,P54802 4 +Caspase activation via dependence receptors in the absence of ligand 0.7575845974329116 2.291584799042199 0.0219296134672561 0.999999999999974 0.126814281156961 2 Q9Y5V3 1 +Mucopolysaccharidoses 0.917980151780492 2.2741163166521017 0.022958993908529 0.999999999999994 0.131687562621685 4 P16278,P15586,P54802 3 +Synthesis of pa 0.7101495043741424 2.2566141739668915 0.024032193918192 0.9999999999999988 0.136182432203088 12 Q8N2A8,Q8NAN2,Q9NUQ2,O15228,Q8NF37,Q9NPH0 6 +Keratan sulfate degradation 0.905394045878238 2.2223950451830596 0.0262566198987259 1.0 0.1459674097619975 4 P16278,P15586 2 +Complex i biogenesis 0.5040563933776471 2.21714562730946 0.0266131417215502 1.0 0.1461133967669549 30 O75306,P51970,Q9Y6M9,Q9NPL8,O96000,Q86Y39,P03886,O75438,O95168,O43676,Q7L592,Q9BQ95,Q9P0J0 13 +Reactions specific to the complex n glycan synthesis pathway 0.7371645274212439 2.190654058985184 0.0284768359786964 1.0 0.154932060214604 2 Q16706 1 +Keratan sulfate keratin metabolism 0.854260185745312 2.189661640443015 0.0285487850147392 1.0 0.154932060214604 6 O60512,P16278,P15586 3 +Endosomal vacuolar pathway 0.885288966725037 2.1392055320979644 0.0324190263571331 1.0 0.168173699227628 4 Q9UIQ6,P01889,P04439 3 +Chondroitin sulfate dermatan sulfate metabolism 0.8841482655942621 2.13446478808805 0.0328047530628987 1.0 0.1689325057363144 4 P06865,Q9UL01 2 +Peroxisomal protein import 0.5428004513300692 2.1183345003728427 0.0341467487569988 1.0 0.1739388537766259 24 Q2T9J0,A8MXV4,O75874,O14734,O15228,O15254,Q15067 7 +Organelle biogenesis and maintenance 0.356902284930086 2.0794884492308636 0.0375724783766897 1.0 0.1853663181451372 104 P48735,P24539,O43805,Q9UBN7,P68371,Q9Y512,Q9H6D7,P30153,P07900,Q15154,Q96KP1,Q10713,P06576,P00367,Q9UPT5,O75964,O75935,P07437,Q13505,Q6UXV4,A6NIH7,P04350,A0AVF1,O95684,P54646,O94927,Q68CZ6,Q92973,Q9NX63,P41208,P56385,Q9NVH1,Q9BUR5,Q16891,Q9Y366,Q5XKP0,Q13885,P53350,P61163,O00411 40 +The activation of arylsulfatases 0.708284714119022 2.0461299154038666 0.0407435904213118 1.0 0.1929167989411777 2 O43681 1 +Release of apoptotic factors from the mitochondria 0.7071178529755016 2.040247665309322 0.0413256644545483 1.0 0.1943683751512256 2 Q9NR28 1 +Acyl chain remodelling of pc 0.7709674790905143 1.9821001130871052 0.0474680369062172 1.0 0.2065403537480003 3 Q9NP80 1 +P75ntr regulates axonogenesis 0.7701985089255907 1.9785576057865055 0.0478658367651283 1.0 0.2065403537480003 3 P61586 1 +Pp2a mediated dephosphorylation of key metabolic factors 0.7680186752261371 1.9685093109775984 0.0490094658564639 1.0 0.2089195055089746 3 P30154,Q14738 2 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.8011948601477135 1.9535000427905571 0.0507603722181351 1.0 0.2131819674287598 6 P01889,P10321,P04439 3 +Class i peroxisomal membrane protein import 0.7099425435716781 1.9454763083880064 0.0517176784339854 1.0 0.2138953222080296 8 O43808,Q8TB36,P51648,P28288,Q9NR77 5 +Cdc6 association with the orc origin complex 0.7619845814549505 1.940646760401781 0.0523011381665283 1.0 0.2144709061660423 3 Q9Y619 1 +Ns1 mediated effects on host pathways 0.4722512980431125 1.9385301076332837 0.052558581273888 1.0 0.2144709061660423 30 Q92621,O75694,Q12769,P52292,Q7Z3B4,Q99567,Q9BW27,Q8NFH4,P49792,P52294,Q5SRE5,Q9BTX1,P35658,Q8N1F7 14 +Selective autophagy 0.4504368856461169 1.938258180243094 0.0525917317742385 1.0 0.2144709061660423 35 P04350,Q8N4H5,Q9NS69,P21796,P54646,Q13315,P08670,Q9UBN7,Q13885,Q8IWA4,P07900 11 +Metabolism of fat soluble vitamins 0.8137765076984231 1.9202036712753396 0.0548321780824994 1.0 0.2197960320295643 5 Q8N0U8 1 +Pregnenolone biosynthesis 0.83115550568674 1.911835966312231 0.0558972369966799 1.0 0.2221718349360996 4 P30536 1 +Autophagy 0.3949000982637225 1.8971708739344173 0.0578053896022232 1.0 0.2238759763492523 53 P04350,P42345,Q8N4H5,Q9NS69,P21796,P54646,P13473,Q13315,P08670,Q9UBN7,P68371,Q7Z3C6,Q13885,Q8IWA4,P07900,Q14457 16 +Metabolism of steroids 0.396402969905934 1.896358745747294 0.0579126230851321 1.0 0.2238759763492523 50 P30536,Q53GQ0,P37268,O14975,P38435,O14734,Q9BWD1,Q16850,P04062,Q15392,Q15800,Q14534,Q14849,P22059,Q14739,O76062 16 +Collagen biosynthesis and modifying enzymes 0.6579896444805621 1.882142910509968 0.0598166145171283 1.0 0.2238759763492523 11 O75718,Q32P28,P13674,O60568 4 +Sumoylation of rna binding proteins 0.4653559488902397 1.87722186240837 0.0604876923207708 1.0 0.2251929653419729 30 P61978,Q92621,Q12769,Q7Z3B4,Q99567,Q9BW27,Q8NFH4,P07910,P49792,Q5SRE5,Q9BTX1,P35658,Q8N1F7 13 +Transport of inorganic cations anions and amino acids oligopeptides 0.683041361772418 1.8724865438289904 0.0611393218155638 1.0 0.2252585033959272 9 Q70HW3,Q9Y6M7,P30825,Q9UBX3 4 +Metabolism of steroid hormones 0.7832469926588542 1.872453607970533 0.0611438744157619 1.0 0.2252585033959272 6 P30536,Q14849 2 +N glycan antennae elongation in the medial trans golgi 0.746625838334912 1.8694193460740816 0.0615644950969416 1.0 0.2256298768358042 3 O60512 1 +Er quality control compartment erqc 0.8182980532418356 1.8571421012065317 0.0632909397533263 1.0 0.2295720205448418 4 Q9UBV2 1 +Nuclear pore complex npc disassembly 0.4861115761933855 1.8475309479818824 0.0646702270620094 1.0 0.2331653690271016 27 P14635,Q92621,Q12769,Q7Z3B4,Q99567,Q8NFH4,O95067,P49792,Q5SRE5,Q9BTX1,P35658,Q8N1F7 12 +Sumoylation of ubiquitinylation proteins 0.5076810672919692 1.8467916775796656 0.0647773385248928 1.0 0.2331653690271016 24 Q92621,O75694,Q12769,Q7Z3B4,Q99567,Q9BW27,Q8NFH4,P49792,Q5SRE5,P14373,Q9BTX1,P35658,Q8N1F7 13 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.6503991736501381 1.8396344695567255 0.0658219202175087 1.0 0.2339413839468636 11 P46379,Q13190,P51648,P05067,P50402,P09601 6 +Regulation of glucokinase by glucokinase regulatory protein 0.5099609062260165 1.8129986484261291 0.0698320297809758 1.0 0.2429419108790851 23 Q92621,Q12769,Q7Z3B4,Q99567,Q8NFH4,P49792,Q5SRE5,Q9BTX1,P35658,Q8N1F7 10 +Alpha oxidation of phytanate 0.8074830121946972 1.8109438218636629 0.0701495482211993 1.0 0.2429419108790851 4 O14975,P51648 2 +Metabolism of folate and pterines 0.6837930911147516 1.8103065402353185 0.0702482633867234 1.0 0.2429419108790851 8 Q9H2D1 1 +Transport of vitamins nucleosides and related molecules 0.7246089113917998 1.797566516044 0.0722457285175135 1.0 0.2446000667524819 7 P12235,Q8TB61 2 +Free fatty acids regulate insulin secretion 0.6566511085180913 1.7828332269204217 0.0746134552221131 1.0 0.2446000667524819 2 O95573 1 +Smac xiap regulated apoptotic response 0.7230391512254225 1.7592125301232198 0.0785414167896974 1.0 0.2468194634527016 3 Q9NR28 1 +Inla mediated entry of listeria monocytogenes into host cells 0.6499416569428298 1.7481953979372191 0.0804301982283157 1.0 0.2503450879609379 2 O60716 1 +Mitochondrial biogenesis 0.4305066436689211 1.7458296380027485 0.0808405592576533 1.0 0.2503450879609379 35 Q9BUR5,Q16891,P06576,P48735,P24539,P00367,P54646,O75964,Q5XKP0,Q9Y512,Q9NX63,O00411,Q13505,Q6UXV4,Q9NVH1 15 +Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.7199262319359009 1.7445972981609112 0.0810549914789753 1.0 0.2503450879609379 3 P00374 1 +Phosphorylation of emi1 0.7186090042777346 1.738408154259101 0.0821389209018863 1.0 0.2503450879609379 3 P53350 1 +Aurka activation by tpx2 0.4115110719274948 1.7370573988403275 0.0823770398864638 1.0 0.2503450879609379 39 P04350,Q15154,O14965,O95684,O94927,O43805,Q68CZ6,P68371,O75935,P53350,P61163,P41208,P07437,Q9H6D7,P07900 15 +Metabolism of cofactors 0.7514063398452064 1.72733492718055 0.0841075299204554 1.0 0.2525015419526865 6 Q5T2R2,O75874,P00374,P07900 4 +Basigin interactions 0.7094536482387004 1.723730662102887 0.0847564770001056 1.0 0.2539095308856669 7 P53985 1 +Nuclear envelope breakdown 0.4047273961617941 1.7206129395981442 0.0853210838429456 1.0 0.2550594264881278 40 P14635,Q92621,Q12769,Q7Z3B4,Q99567,Q8NFH4,P50402,O95067,P49792,P53350,Q5SRE5,P42166,Q9BTX1,P35658,Q8N1F7 15 +Ire1alpha activates chaperones 0.4778413253184807 1.7183907866498347 0.0857253597255947 1.0 0.2557261788008755 26 O43731,O14773,Q9NWM8,P43307 4 +Wax and plasmalogen biosynthesis 0.7652816935481763 1.7063242750444212 0.0879477208318384 1.0 0.260155627030868 5 Q96K12,Q6IAN0,O15228 3 +Recruitment of mitotic centrosome proteins and complexes 0.4031669010790841 1.7040844983006398 0.088365302241248 1.0 0.2602994602555344 40 P21127,Q15154,P04350,O94927,O95684,O43805,Q68CZ6,P68371,O75935,P53350,P61163,P41208,P07437,Q9H6D7,P07900 15 +Biological oxidations 0.3802036886061187 1.6997050600659291 0.0891864170841583 1.0 0.2616258513633002 48 O15217,P16435,P05091,P07099,O43169,Q06520,Q16850,Q8TB61,Q99707,Q9NUJ1 10 +Neutrophil degranulation 0.307060675608484 1.6980450662741942 0.0894992564232779 1.0 0.2616844802931558 179 O75874,Q5T9A4,P61916,O00560,P10321,O00264,P06280,P08236,Q4KMQ2,P07602,O14975,P16278,P30519,Q92820,Q9Y5Z4,P20618,P10253,P07437,Q7L576,P17900,Q969Q5,Q9BTY2,P61586,P15586,P42785,Q9NZJ7,Q99519,Q9H7Z7,Q93050,O00584,Q9NQX7,O15260,P10619,P13473,P01889,P04439,Q8NF37,Q13510,Q07065 39 +Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.7630383235912422 1.696345875567473 0.0898203973343616 1.0 0.2616844802931558 5 P12235,P12236 2 +Interleukin 4 and interleukin 13 signaling 0.5981951662222083 1.6960136769590353 0.0898832899493173 1.0 0.2616844802931558 13 P14625,P08670,P04083,Q07820,P09601 5 +Amino acid transport across the plasma membrane 0.7070956129461763 1.6841949732767407 0.0921439944065416 1.0 0.2669716141840457 3 P30825 1 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.6987073427618531 1.671135805540067 0.0946948564481235 1.0 0.2710232098342847 7 Q9NR77 1 +Collagen formation 0.5796393835673467 1.6590541235775598 0.0971048865199901 1.0 0.2746425240449635 14 O75718,Q32P28,P13674,O60568 4 +Trna modification in the mitochondrion 0.7365184284072532 1.6589428973071372 0.0971272994319183 1.0 0.2746425240449635 6 O75648 1 +Nuclear envelope ne reassembly 0.3761612664295211 1.6497322336820277 0.0989977143712894 1.0 0.2766054950057216 46 P04350,P14635,Q92621,Q12769,Q7Z3B4,Q8NFH4,Q8N1F7,P50402,Q92973,O95067,P68371,Q13885,Q5SRE5,P42166,Q9BTX1,P30153,Q14739,Q86XL3 18 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.7326411239523352 1.641080000653904 0.100780809639577 1.0 0.2791845462567506 6 P30154,Q16537,P48729,Q14738 4 +Beta catenin phosphorylation cascade 0.7326411239523352 1.641080000653904 0.100780809639577 1.0 0.2791845462567506 6 P30154,Q16537,P48729,Q14738 4 +Signaling by ctnnb1 phospho site mutants 0.7326411239523352 1.641080000653904 0.100780809639577 1.0 0.2791845462567506 6 P30154,Q16537,P48729,Q14738 4 +Sumoylation of sumoylation proteins 0.4798540695084589 1.6273133582904968 0.1036705622359801 1.0 0.2842373963945387 24 Q92621,Q12769,Q7Z3B4,Q99567,Q8NFH4,P49792,Q5SRE5,Q9BTX1,P35658,Q8N1F7 10 +Glycogen storage diseases 0.7647838502715426 1.626969253576176 0.1037436280249379 1.0 0.2842373963945387 4 P10253,Q04446 2 +Processing of smdt1 0.6241624710367317 1.6212149169960843 0.1049715546967964 1.0 0.2863713307621039 10 Q8IYU8,Q10713 2 +Diseases of carbohydrate metabolism 0.6224854441822647 1.6119111362131868 0.1069812785169783 1.0 0.2863713307621039 10 P16278,P08236,P15586,P54802 4 +Export of viral ribonucleoproteins from nucleus 0.470828893139145 1.605910719505944 0.1082935279140671 1.0 0.2888509789919635 25 Q92621,Q12769,Q7Z3B4,Q99567,Q8NFH4,P49792,Q5SRE5,Q9BTX1,P35658,Q8N1F7 10 +O linked glycosylation 0.7418978102189406 1.6019908391609323 0.1091576352660257 1.0 0.2899237641134295 5 Q8NAT1,O43505,Q10472,Q8N4A0 4 +Rnd1 gtpase cycle 0.544857060646639 1.600605164913821 0.1094643975867089 1.0 0.2899237641134295 16 Q9NNW5,Q8TAA9,P51648,P38159 4 +Cristae formation 0.5041115092750066 1.6002639586112577 0.1095400387443956 1.0 0.2899237641134295 19 Q9BUR5,Q16891,P06576,P24539,O75964,Q5XKP0,Q9Y512,Q9NX63,Q13505,Q6UXV4,Q9NVH1 11 +Cholesterol biosynthesis 0.5155196323692685 1.582635471721808 0.1135045737047431 1.0 0.2966147673136655 18 P37268,Q9BWD1,Q16850,Q15392,Q15800,Q14534,Q14739,O76062 8 +Activation of ampk downstream of nmdars 0.671450368662639 1.5369418510353705 0.1243075496855032 1.0 0.3171753211686168 7 P04350,P54646,Q13885,P68371,Q9BVA1 5 +Gene silencing by rna 0.3657834766407324 1.5304807648251568 0.1258977710970901 1.0 0.3194995593848815 44 Q9HAV4,Q8N2A8,Q12769,O15397,Q7Z3B4,Q99567,Q8NFH4,Q9Y2W6,O75569,Q5SRE5,P30876,Q9BTX1,P35658,Q8N1F7 14 +Recruitment of numa to mitotic centrosomes 0.3710544149479497 1.5277798355233538 0.1265672103963877 1.0 0.3200471933141632 43 P04350,Q15154,O95684,O94927,O43805,Q68CZ6,P61163,P68371,O75935,Q13885,P53350,P41208,P07437,Q9H6D7,P07900 15 +O linked glycosylation of mucins 0.7416812609456883 1.5265199814143604 0.1268804180876102 1.0 0.3202652413624651 4 O43505,Q8N4A0,Q10472 3 +Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.6064760793465673 1.5218410595202276 0.1280489105726476 1.0 0.3209183176163514 2 P52292 1 +Peroxisomal lipid metabolism 0.5572833746087941 1.5200642873546806 0.1284948191331243 1.0 0.3214648755263092 14 A8MXV4,O14975,P51648,O14734,O15254,Q15067 6 +Ptk6 regulates rho gtpases ras gtpase and map kinases 0.739798853220434 1.5183119879014175 0.1289357670180271 1.0 0.3219971101990022 4 P61586 1 +Metabolism of porphyrins 0.6161201839631185 1.5128051644742495 0.1303291566092947 1.0 0.3220529527246496 9 P09601,P30519,Q7KZN9,P22830 4 +G alpha i signalling events 0.4528254170178465 1.5110171416525662 0.1307840835657152 1.0 0.3220529527246496 26 P07602,P05067,Q9NZJ7,P04083,O43865,Q14738 6 +E2f enabled inhibition of pre replication complex formation 0.7377960644568979 1.5095756026974405 0.1311517506009738 1.0 0.3223956796131952 4 Q9Y619,Q9UBD5 2 +Stimuli sensing channels 0.602134723890535 1.4986172794122783 0.1339729474125253 1.0 0.3280016469351414 10 Q9C0H2,Q4KMQ2 2 +Synthesis of very long chain fatty acyl coas 0.6601863994214021 1.4812009142280829 0.1385530426756416 1.0 0.3353316350177192 7 Q9P035,Q53GQ0 2 +Mastl facilitates mitotic progression 0.6956334790745463 1.4696628928672657 0.1416530773962319 1.0 0.3376224530508162 6 P30154,P30153,Q96GX5 3 +Phase i functionalization of compounds 0.5346053794327235 1.4522336014250703 0.1464366626668052 1.0 0.345005131588378 15 Q16850,P07099,O43169,P16435 4 +Transport of the slbp dependant mature mrna 0.427386165644181 1.4065314006376874 0.1595663871101615 1.0 0.3660945889633138 28 Q92621,Q12769,Q7Z3B4,Q99567,Q8NFH4,P49792,Q5SRE5,Q9BTX1,P35658,Q8N1F7 10 +Hyaluronan metabolism 0.6959681843763524 1.3953473397007377 0.1629111230173778 1.0 0.3725568793800975 5 P06865 1 +Hyaluronan uptake and degradation 0.6959681843763524 1.3953473397007377 0.1629111230173778 1.0 0.3725568793800975 5 P06865 1 +Met activates pi3k akt signaling 0.581971995332567 1.3930771601086094 0.1635964589796912 1.0 0.3735187760846995 2 Q9NWH9 1 +Glycerophospholipid catabolism 0.5808051341890405 1.386932033523445 0.1654624887696338 1.0 0.3765605994418603 2 Q8IY17 1 +Intra golgi traffic 0.521279678921518 1.366219687266201 0.1718700200082019 1.0 0.3892593872095874 15 Q13190,Q16706,O60476,Q8TBA6,O00461 5 +Activated notch1 transmits signal to the nucleus 0.6397520247714734 1.3637394713027335 0.1726495765018427 1.0 0.3903983212245194 3 Q92542 1 +Role of lat2 ntal lab on calcium mobilization 0.5752625437573045 1.3577309801102264 0.1745490626830579 1.0 0.3940619639132715 2 P62993 1 +Pyruvate metabolism 0.4828909440908711 1.3520824914107783 0.1763489276607066 1.0 0.3955935404280716 18 Q15120,Q15118,P21796,P53985,P35613 5 +Signaling by gpcr 0.3492990052085163 1.345495131590965 0.1784653924265387 1.0 0.3972619415964534 53 Q15418,P52429,P07602,P42892,P05067,Q92974,P61586,P30154,Q9NZJ7,P04083,O43865,Q9BYT8,Q14738 13 +Sulfur amino acid metabolism 0.5514553701276608 1.3405915930336971 0.1800530882779183 1.0 0.3994574018241238 12 Q13126,Q9UBX3 2 +Dap12 interactions 0.6309766115890652 1.3360977229298636 0.1815173341843392 1.0 0.4020218496945674 7 P01889 1 +Sialic acid metabolism 0.6656588358428461 1.3299157088145692 0.1835460450691131 1.0 0.4020218496945674 6 P10619,P16278 2 +Sumoylation of dna replication proteins 0.3920124918923723 1.305716545395676 0.1916489692868268 1.0 0.4141143884589781 33 Q96GD4,Q92621,Q12769,O14965,Q7Z3B4,Q99567,Q8NFH4,P49792,Q5SRE5,Q9BTX1,P35658,Q8N1F7 12 +Prevention of phagosomal lysosomal fusion 0.6265827274203501 1.300652220796588 0.1933775236095187 1.0 0.4159385454466935 3 Q9H267 1 +Regulation of plk1 activity at g2 m transition 0.3450418003784037 1.2893057600330031 0.1972918092843174 1.0 0.4185939447224026 44 P04350,Q15154,P14635,O14965,O94927,O95684,O43805,Q68CZ6,O95067,P68371,O75935,P53350,P61163,P41208,P07437,Q9H6D7,P30153,P07900 18 +Nuclear import of rev protein 0.4202934063326303 1.2889916741187295 0.1974009811078247 1.0 0.4185939447224026 27 Q92621,Q12769,Q7Z3B4,Q99567,Q8NFH4,P49792,Q5SRE5,Q9BTX1,P35658,Q8N1F7 10 +Translation of sars cov 2 structural proteins 0.4847509249234755 1.2794808917978444 0.2007277642552334 1.0 0.4218540285259262 17 Q16706,Q10472,P48729,P04844,P46977,Q9H0U3,P27824 7 +Activation of smo 0.6218074305133673 1.2777665023369311 0.20133176881217 1.0 0.4221086564546389 3 P48729 1 +Antigen presentation folding assembly and peptide loading of class i mhc 0.4571230399701872 1.2564572489550327 0.2089502365190751 1.0 0.4348507134637391 19 P51572,P10321,P01889,O95487,P04439,Q03519,Q6P179,Q9NZ08,Q03518 9 +Nef and signal transduction 0.5536756126021113 1.24390103094505 0.2135359898988165 1.0 0.4409487084870771 2 P63000 1 +Hcmv early events 0.3506445363724987 1.2396977615138995 0.2150872054258827 1.0 0.4417584379271042 42 P04350,Q15022,Q92621,Q12769,Q7Z3B4,Q99567,Q8NFH4,P49792,P68371,Q13885,Q5SRE5,Q9BTX1,P35658,Q8N1F7 14 +Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.6747742764936234 1.2334568029047304 0.2174053836117271 1.0 0.4445782554726767 4 O14734 1 +Defects in cobalamin b12 metabolism 0.6595214492569205 1.2304730777051736 0.2185200025857041 1.0 0.4455660746364575 5 Q99707,O14678 2 +Cobalamin cbl vitamin b12 transport and metabolism 0.6595214492569205 1.2304730777051736 0.2185200025857041 1.0 0.4455660746364575 5 Q99707,O14678 2 +Cell surface interactions at the vascular wall 0.487704165256686 1.220863367490354 0.2221377564434288 1.0 0.4509875889808317 16 P53985,Q92896 2 +Post translational modification synthesis of gpi anchored proteins 0.5668912134542461 1.1919062907768927 0.2332979912601493 1.0 0.4674965503835239 8 O60762,O43292,Q9H490 3 +Gap junction assembly 0.6490880867333807 1.1832687385665233 0.2367026581469269 1.0 0.4697432498527621 5 P04350,Q13885,P68371 3 +Transport of connexons to the plasma membrane 0.6490880867333807 1.1832687385665233 0.2367026581469269 1.0 0.4697432498527621 5 P04350,Q13885,P68371 3 +Anchoring of the basal body to the plasma membrane 0.3585132128295438 1.178441629854246 0.2386205895775757 1.0 0.4709002124391039 39 P04350,Q15154,O95684,O94927,O43805,Q68CZ6,P68371,O75935,P53350,P61163,P41208,P07437,Q9H6D7,P07900 14 +Rac2 gtpase cycle 0.353998139979967 1.1759886709422047 0.23959940323329 1.0 0.4721714496678382 40 O15173,Q9Y2A7,P50402,Q9Y512,Q7L576,Q13505,Q14739,Q86XL3 8 +Insulin processing 0.553657041412805 1.1715745686956935 0.2413679033227229 1.0 0.4749931821316068 9 P33176,Q9UPT5 2 +Platelet sensitization by ldl 0.6459999720868871 1.169304435388275 0.2422809967883137 1.0 0.4761260257218811 5 P30154,Q16537,Q14738 3 +Transport of mature mrnas derived from intronless transcripts 0.3743768509082676 1.1621081393066397 0.2451915416696002 1.0 0.4798408672618667 34 Q92621,O75694,Q12769,Q7Z3B4,Q99567,Q9BW27,Q8NFH4,Q6UN15,P49792,Q5SRE5,Q9BTX1,P35658,Q8N1F7 13 +Rnd3 gtpase cycle 0.4430309988101888 1.152745489633178 0.249014864164387 1.0 0.4826373260109204 19 Q8TAA9,P38159,O75976,Q07065,Q9NNW5 5 +Synthesis of pips at the golgi membrane 0.5939498691698716 1.1517227017552152 0.249435040448597 1.0 0.4827885350795203 7 Q9BTU6,Q10713 2 +Intraflagellar transport 0.5075991100873994 1.1446782571474394 0.2523424614732499 1.0 0.4855605413125681 13 P04350,A0AVF1,Q9Y366,Q92973,Q13885,P68371,Q9P2L0,Q9BVA1,Q9Y496 9 +Ptk6 regulates cell cycle 0.5332555425904475 1.1363192938425764 0.2558229588476652 1.0 0.4859532014366592 2 P11802 1 +Assembly of the orc complex at the origin of replication 0.5564334942712081 1.1361549322632594 0.2558917283256114 1.0 0.4859532014366592 8 P52294,Q9Y619 2 +Pre notch processing in golgi 0.646450004777429 1.1092968523812836 0.2673021425219999 1.0 0.499103780744541 4 Q9UBV2,P16615 2 +Maturation of sars cov 2 spike protein 0.5221726815606378 1.1055227862772958 0.2689331264836472 1.0 0.4994914183694278 11 Q16706,P04844,P46977,Q9H0U3,P27824 5 +G1 s specific transcription 0.5110247587039084 1.100445410756578 0.2711381020272685 1.0 0.5007537460215652 12 P00374,Q9Y619 2 +Met interacts with tns proteins 0.5259626604434237 1.0979884989182014 0.2722095114014742 1.0 0.5020199118052394 2 Q9NWH9 1 +Phosphorylation of the apc c 0.5086320205747606 1.086258686937792 0.2773645593289982 1.0 0.5089224879235584 12 Q9UJX4,P14635,Q9UJX2,Q9H1A4,Q13042,P53350 6 +G2 m dna replication checkpoint 0.6378150548177715 1.071556001121886 0.2839195046917193 1.0 0.5174210684836509 4 O95067 1 +Interferon alpha beta signaling 0.5237989116965078 1.0591862968236927 0.2895149445049427 1.0 0.5238095020447014 10 P01889,P04439 2 +Ctla4 inhibitory signaling 0.6008080975945926 1.0274264857789832 0.3042196852132983 1.0 0.5419873432272272 6 P30154,Q16537,Q14738 3 +Snrnp assembly 0.3476357747989124 1.0215808908043895 0.3069793057846413 1.0 0.5455261970555779 38 Q92621,Q12769,P35658,Q7Z3B4,Q99567,Q8NFH4,O14744,P49792,Q5SRE5,P62316,Q9UHI6,Q9BTX1,Q16637,Q8N1F7 14 +Hcmv late events 0.3680729580495228 1.0175656234044723 0.3088844311328866 1.0 0.548221298526419 31 P61978,Q92621,Q12769,Q7Z3B4,Q99567,Q8NFH4,P49792,Q5SRE5,Q9BTX1,P35658,Q8N1F7 11 +Sumoylation of chromatin organization proteins 0.3612157907240929 1.0075913785680728 0.3136506695225467 1.0 0.5532013683703918 33 Q15022,Q92621,Q12769,Q7Z3B4,Q99567,Q9BW27,Q8NFH4,P49792,Q5SRE5,Q9BTX1,P35658,Q8N1F7 12 +Synaptic adhesion like molecules 0.6070071185212694 0.9936845322613516 0.3203764754419449 1.0 0.5597351748765707 5 O95197,O75955 2 +Energy dependent regulation of mtor by lkb1 ampk 0.5609239250270001 0.9880238235565396 0.323140980784482 1.0 0.5635994114794861 7 P54646 1 +Suppression of phagosomal maturation 0.5916774011604957 0.985146299726139 0.3245522137126451 1.0 0.5652146973527169 6 Q9H267,P52294 2 +Role of phospholipids in phagocytosis 0.590772625451875 0.9809648588358708 0.3266100711953463 1.0 0.5654562091492438 6 Q8IV08 1 +Plasma lipoprotein clearance 0.4797733099021904 0.9750169823858664 0.3295518361309946 1.0 0.5691525590952673 13 Q8WTV0,P35610,O15118 3 +Postmitotic nuclear pore complex npc reformation 0.4147162498891655 0.9706778967176972 0.3317087020085552 1.0 0.5721772353717254 20 Q12769,Q7Z3B4,Q8NFH4,Q92973,Q5SRE5,Q9BTX1,Q8N1F7 7 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.6014187840816647 0.9686869312764812 0.3327014150013974 1.0 0.5731888846971572 5 Q8NB78 1 +Interferon gamma signaling 0.4729344237634431 0.9335864366957484 0.350517264404254 1.0 0.598040943258044 13 P01889,P04439 2 +Cilium assembly 0.3064968528583048 0.9319377877821088 0.3513686775086548 1.0 0.5987695700056909 69 O43805,Q9UBN7,P68371,Q9H6D7,P30153,P07900,Q15154,Q96KP1,Q10713,Q9UPT5,O75935,P07437,A6NIH7,P04350,A0AVF1,O94927,O95684,Q68CZ6,Q92973,P41208,Q9Y366,Q13885,P53350,P61163 24 +Transport to the golgi and subsequent modification 0.2841798107104586 0.9239476223778768 0.3555135868097092 1.0 0.6037311297429826 82 P24390,P04066,O60512,P68371,Q9HCU5,P49755,Q08379,O15020,Q13190,Q16706,Q15363,Q9BVK6,O95249,P49257,Q9UJW0,O75935,Q13813,P04350,O15498,Q9Y3B3,Q9BVA1,Q96PC5,O43731,O60476,Q12907,Q13885,P61163,O95487,Q8IUR0 29 +Rhog gtpase cycle 0.328465252602149 0.9001350684559165 0.3680483756147592 1.0 0.614208903388372 40 Q13190,O15173,Q8TAA9,P50402,P49257,O95202,Q7L576,P42166,Q14739,Q86XL3 10 +Cytosolic sulfonation of small molecules 0.5843372442433743 0.8926958337917452 0.372020082069084 1.0 0.6162838558929733 5 Q8TB61 1 +Extracellular matrix organization 0.3489192734829873 0.8890942237700211 0.3739524429958503 1.0 0.6162838558929733 33 Q32P28,P05067,P35613,O75718,P13674,O60568 6 +Intra golgi and retrograde golgi to er traffic 0.2834799457400179 0.8839784152033483 0.3767078648542024 1.0 0.6162838558929733 95 Q8TD16,Q9P2W9,P24390,Q8TBA6,P68371,A2RRP1,P49755,O00461,Q13190,Q16706,Q15363,Q9BVK6,P33176,O95249,Q5VZE5,Q9UJW0,O75935,Q9Y496,P04350,Q6NUQ1,Q10472,O15498,Q9Y3B3,Q9NSK0,O43731,O15260,O60476,Q13885,P61163,Q10471 30 +Nr1h2 and nr1h3 mediated signaling 0.5396122541014476 0.8835010996405958 0.3769655886609793 1.0 0.6162838558929733 7 Q8NB78,Q9HCE1,O00767 3 +Glutamate neurotransmitter release cycle 0.5380799533119485 0.8795747275409989 0.379089734635587 1.0 0.6162838558929733 3 O94925,O75915 2 +Sumoylation of dna damage response and repair proteins 0.3142541993782896 0.8789729459125134 0.3794159448620817 1.0 0.6162838558929733 43 P41208,Q92621,Q12769,Q7Z3B4,Q99567,Q9BW27,Q8NFH4,P49792,Q5SRE5,Q96MF7,Q9BTX1,P35658,Q8N1F7 13 +Signaling by vegf 0.3491714356122569 0.8701562543307685 0.38421501876021 1.0 0.6209696486918738 32 P42345,O14786,Q9Y2A7,P61586,P46108,Q9UQB8,Q7L576,O43865,P07900 9 +Hcmv infection 0.3104347709966081 0.8693781927656743 0.3846403068438679 1.0 0.6209696486918738 49 P04350,Q15022,P61978,Q92621,Q12769,Q7Z3B4,Q99567,Q8NFH4,P49792,P68371,Q13885,Q5SRE5,Q9BTX1,P35658,Q8N1F7 15 +Rho gtpases activate ktn1 0.4974074436293438 0.8663000828876259 0.3863256208462085 1.0 0.6222664965913244 9 P33176,P61586 2 +Pyruvate metabolism and citric acid tca cycle 0.3357938286107871 0.8624239093953103 0.3884542881662067 1.0 0.6247205363602072 37 P21796,P48735,Q15118,P53985,P35613,Q13423 6 +P38mapk events 0.4778296382730617 0.8480402018381342 0.3964155821226891 1.0 0.6298900747467504 2 P11233 1 +Platelet homeostasis 0.4759723990707242 0.8415371238444472 0.4000470967090914 1.0 0.6337078165863919 11 P20020,P16615,P30154,Q16537,P30153,Q14738 6 +Elastic fibre formation 0.5261161365626056 0.8239458305315761 0.4099703378156958 1.0 0.6413172357626905 3 P55081,P06756 2 +Molecules associated with elastic fibres 0.5261161365626056 0.8239458305315761 0.4099703378156958 1.0 0.6413172357626905 3 P55081,P06756 2 +Costimulation by the cd28 family 0.4443181250327272 0.8131758149681191 0.4161172635646379 1.0 0.6480590053970244 14 P42345,Q16537,Q14738 3 +Viral messenger rna synthesis 0.3460299148729194 0.812138606749881 0.4167121025392832 1.0 0.6482698750638684 31 Q92621,Q12769,Q7Z3B4,Q99567,Q8NFH4,P49792,Q5SRE5,P30876,Q9BTX1,P35658,Q8N1F7 11 +Maturation of sars cov 1 spike protein 0.5772896794591367 0.8106401468117924 0.4175723545712488 1.0 0.6488927227973923 4 P27824 1 +Beta oxidation of pristanoyl coa 0.564529833255657 0.8055992563446221 0.4204739545464884 1.0 0.6526828931409188 5 O15254 1 +Apc c cdc20 mediated degradation of cyclin b 0.4691324279784009 0.8031006497126513 0.4219165622215099 1.0 0.6537275240171652 11 Q9UJX4,P14635,Q9UJX2,Q9H1A4,Q13042 5 +Signaling by erbb4 0.4928780887177754 0.8015968073606852 0.4227862250234477 1.0 0.6537275240171652 8 Q92542,P46934 2 +Cardiac conduction 0.4403389742514337 0.7888251112547557 0.4302142306025132 1.0 0.6612552062964555 14 Q9HD47,P20020,O43865,P16615 4 +Initiation of nuclear envelope ne reformation 0.3918510246611713 0.7794645895138882 0.4357060889697761 1.0 0.6689223527618601 19 P50402,O95067,P42166,P30153,Q14739,Q86XL3 6 +Interaction between l1 and ankyrins 0.5674404784319639 0.7691473321826829 0.4418058523055235 1.0 0.6753933451821166 4 O15020,Q13813 2 +Translation of sars cov 1 structural proteins 0.5436614621559462 0.7662813944459237 0.4435088864300884 1.0 0.6772630289533061 6 Q10472 1 +Interactions of rev with host cellular proteins 0.3432122036374572 0.7611704842159533 0.4465552452690176 1.0 0.6797081457115252 30 Q92621,Q12769,Q7Z3B4,Q99567,Q8NFH4,P49792,Q5SRE5,Q9BTX1,P35658,Q8N1F7 10 +Regulation of lipid metabolism by pparalpha 0.371194292521655 0.7554598303589027 0.4499731258951114 1.0 0.6827011619763464 24 Q06520,P23786,P37268 3 +Camk iv mediated phosphorylation of creb 0.5077327108258102 0.7396614448819337 0.4595054480503875 1.0 0.6919553758795056 3 P52292,Q13555 2 +Negative regulation of the pi3k akt network 0.4232591838970658 0.7368276251825737 0.4612271813522661 1.0 0.6937963890307498 15 Q16537,Q8TBX8,Q14738 3 +Unfolded protein response upr 0.3053506103282566 0.7336677959203477 0.4631512304172953 1.0 0.6944807503919275 42 O43731,O14773,P43307,P14625,Q9Y5M8,Q92945,Q9NWM8 7 +Vitamin c ascorbate metabolism 0.5035958643243905 0.7209312089035332 0.4709518401352714 1.0 0.7017033225246758 3 P11166 1 +Sars cov 2 infection 0.3643391172938313 0.701785137168463 0.4828131690876955 1.0 0.7155980898978346 24 Q16706,Q10472,P27824,P48729,P04844,P46977,Q9H0U3,Q14457 8 +Phase ii conjugation of compounds 0.333345037927024 0.6957350242337591 0.4865947871636051 1.0 0.7187523020337219 31 O15217,Q06520,Q8TB61,Q99707,Q9NUJ1 5 +Constitutive signaling by overexpressed erbb2 0.5489527751171667 0.6923683816955193 0.4887060166815091 1.0 0.7198516246833232 4 Q16543 1 +Small interfering rna sirna biogenesis 0.5456272946600129 0.6787327957092288 0.497307182276907 1.0 0.7267854738361452 4 O75569,Q15631 2 +Response to elevated platelet cytosolic ca2 0.3285713564022754 0.6774075735780868 0.4981473944027206 1.0 0.7268727750798746 32 O43852,P07602,Q08380,P05067,Q9NZJ7,P13473,O94919,Q8NBX0 8 +Inflammasomes 0.5326264841228995 0.6686127641638203 0.5037425281638293 1.0 0.7284092979369434 5 P09601 1 +Purinergic signaling in leishmaniasis infection 0.5326264841228995 0.6686127641638203 0.5037425281638293 1.0 0.7284092979369434 5 P09601 1 +The nlrp3 inflammasome 0.5326264841228995 0.6686127641638203 0.5037425281638293 1.0 0.7284092979369434 5 P09601 1 +Copi dependent golgi to er retrograde traffic 0.2932441718508321 0.6615294726505581 0.508272820124539 1.0 0.7332820723193486 52 P04350,O43731,O15260,Q9P2W9,Q6NUQ1,P24390,P33176 7 +Ldl clearance 0.4398539286377284 0.6418742614669339 0.5209548272685502 1.0 0.7439952037205713 11 P35610,O15118 2 +Synthesis of bile acids and bile salts 0.459512941670923 0.6328485746571154 0.5268325326555601 1.0 0.7486638843184363 8 O14975,P22059,O14734 3 +Bile acid and bile salt metabolism 0.459512941670923 0.6328485746571154 0.5268325326555601 1.0 0.7486638843184363 8 O14975,P22059,O14734 3 +Iron uptake and transport 0.3803248878390833 0.6322545020609062 0.5272205885712835 1.0 0.7486638843184363 18 P09601,P30519,Q9Y487 3 +Regulation of tp53 activity 0.2903375782664005 0.62653034260887 0.5309671412456303 1.0 0.7522034500979762 53 P42345,P40937,O14965,P54646,O14744,Q13315,Q13535,Q9UQ84,Q8TBX8,Q92804 10 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.4502276603641943 0.6199206093779625 0.5353100564631315 1.0 0.7564757741717367 9 Q9UJX4,Q9H1A4,Q9UJX2,Q13042 4 +Signaling by wnt in cancer 0.4554032227932029 0.6126210369255884 0.5401269449859427 1.0 0.7594463254192807 8 Q16537,P48729,Q14738 3 +Signalling to ras 0.4779690691567133 0.6073107738528996 0.543644689719537 1.0 0.7625076115251161 3 P11233,P62993 2 +Notch3 activation and transmission of signal to the nucleus 0.5251057299877132 0.5959833381523829 0.5511863576421852 1.0 0.7707868688137991 4 P67809 1 +Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.4494405577484428 0.5835389221694749 0.5595305631816934 1.0 0.7793658683606806 8 Q9UQ84 1 +Resolution of d loop structures 0.4494405577484428 0.5835389221694749 0.5595305631816934 1.0 0.7793658683606806 8 Q9UQ84 1 +Rac3 gtpase cycle 0.3045712148489629 0.580278866227745 0.5617265768090673 1.0 0.7815883955724355 38 O15173,Q8TAA9,Q8IZP0,Q9Y2A7,P50402,P49257,Q9UQB8,Q7L576,P42166,Q14739 10 +Attachment of gpi anchor to upar 0.5068684049164418 0.5621804447781494 0.5739930834987133 1.0 0.7940237655065533 5 O43292 1 +Plasma lipoprotein assembly remodeling and clearance 0.3694238969331587 0.5598826603697271 0.5755594767010188 1.0 0.794851663169045 18 Q8WTV0,P35610,Q9BU23,O15118 4 +Tp53 regulates metabolic genes 0.3095469209107599 0.5558069267563897 0.5783428497579548 1.0 0.7961383034229017 35 P42345,Q9HCE1,P54646,P13073,P00403 5 +Diseases of glycosylation 0.3564883918748296 0.549177605079788 0.5828835716703076 1.0 0.8016069392074113 20 P10619,Q14376,P16278,Q99519,Q96L58,P06865,Q2TAA5 7 +Gamma carboxylation hypusine formation and arylsulfatase activation 0.4221930725455014 0.5481295954811247 0.5836029203943278 1.0 0.8018147231513111 11 O60725,P38435,Q9BU89 3 +Assembly and cell surface presentation of nmda receptors 0.4142887920824596 0.5453365566085893 0.5855220660115288 1.0 0.8036689057804154 12 P04350,O14936,Q14168,Q13885 4 +E2f mediated regulation of dna replication 0.4284234223360277 0.5442009807085741 0.5863031770434155 1.0 0.8039589726027787 10 P30154,P30153,Q9UBD5,Q9Y619 4 +Golgi to er retrograde transport 0.2682844198073418 0.5332762728927911 0.5938423497837937 1.0 0.8095763821690173 75 P04350,O43731,O15260,Q9P2W9,Q6NUQ1,P24390,P33176,Q10472,Q9UJW0,O75935 10 +Cyclin a b1 b2 associated events during g2 m transition 0.41109633769014 0.5282471884203216 0.5973277812289186 1.0 0.8102502917398782 12 P30154,O95067,Q9Y570,P53350,P30153 5 +Disinhibition of snare formation 0.455538870262121 0.5120842924973793 0.6085920172074721 1.0 0.8201751062843774 3 O00186 1 +Reduction of cytosolic ca levels 0.4985084502043613 0.4930340970198045 0.6219884951989292 1.0 0.8302987386241146 4 P16615 1 +Platelet calcium homeostasis 0.4985084502043613 0.4930340970198045 0.6219884951989292 1.0 0.8302987386241146 4 P16615 1 +Regulation of pyruvate dehydrogenase pdh complex 0.4222619498537302 0.4824981885947357 0.6294520848898781 1.0 0.8370941487084054 9 Q15118,Q15120 2 +Cargo concentration in the er 0.3789697242654901 0.4709035140641292 0.6377096384824512 1.0 0.8448760780090961 15 Q13190,Q96PC5,Q15363,Q12907,P49257,Q9HCU5,O95487 7 +Processing of capped intron containing pre mrna 0.2481979893153529 0.4696417569893402 0.6386109860602649 1.0 0.8448760780090961 179 P55769,P61978,Q9BWJ5,P14866,P52756,P17844,P67809,Q14103,Q96FV9,Q5SRE5,P35658,P51991,Q7Z3B4,Q99567,Q13151,P07910,Q15427,Q92733,P52597,O43390,P55795,P62995,P31943,P26368,P22626,P62316,P30876,Q9BTX1,Q8N1F7,Q9BUJ2,Q6P2Q9,P38159,Q00839,Q92621,Q12769,Q8NFH4,O95391,P35637,Q08211,Q9UHX1,Q01081,O75400 42 +Peptide hormone metabolism 0.3847070102397825 0.4632233328310197 0.6432042931991075 1.0 0.8481880913120942 14 P33176,Q9UPT5,P67812 3 +Formation of atp by chemiosmotic coupling 0.4177042789733226 0.4609587945347616 0.6448281682492059 1.0 0.8495355232489538 9 O75964 1 +Sars cov infections 0.2747843122562397 0.4363257486963762 0.6626004027143018 1.0 0.8695128316293677 60 P49354,Q16706,P05023,Q10472,P27824,P48729,P04844,P46977,Q9H0U3,P07437,Q99720,P21964,P07900,Q14457 14 +Innate immune system 0.2357015133193486 0.4081362637397701 0.6831736378020641 1.0 0.8827454239365499 298 O75874,Q5T9A4,O00560,P10321,P49721,O00264,P06280,Q9UQB8,Q9BQ95,P08236,Q4KMQ2,P07602,O14975,P16278,P30519,P14625,Q9Y487,Q92820,Q9Y5Z4,P46108,P20618,P10253,P07437,Q7L576,P09601,P17900,Q969Q5,P28072,Q9BTY2,Q9Y2A7,P05067,P15586,P42785,P61586,Q99519,Q9NZJ7,Q9H7Z7,O43865,Q93050,Q9NQX7,O15260,P10619,Q15418,P13473,P01889,P04439,Q8IV08,Q13510,Q07065,Q14738 50 +Piwi interacting rna pirna biogenesis 0.4053169246277674 0.4038578805530954 0.6863172306886658 1.0 0.8851861174604272 9 Q9Y2W6 1 +Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.4333373949691249 0.3995682427749435 0.6894745508190765 1.0 0.8884462020143534 7 O14734,Q15067 2 +Arms mediated activation 0.4247261649481442 0.3897950040594145 0.6966881383353691 1.0 0.8944740338409517 3 P46108 1 +Adenylate cyclase inhibitory pathway 0.4236941931718793 0.3859013525613198 0.6995697288731746 1.0 0.8957285729946002 3 P63096,P04899 2 +Rnd2 gtpase cycle 0.3411952011238931 0.3815866541110224 0.7027679849775677 1.0 0.8981935025392644 18 Q8TAA9,P38159,P51648,Q07065,Q9NNW5 5 +Asparagine n linked glycosylation 0.2491426028508738 0.3756053287803029 0.7072103285934195 1.0 0.9014216564094985 127 P24390,Q9UBV2,O60512,P68371,Q9HCU5,Q9H0U3,O15020,Q2TAA5,Q13190,Q16706,P16278,O95249,P49257,P46977,Q9UJW0,O75935,P04350,Q86YN1,Q99519,Q9Y3B3,Q13438,P27824,Q96PC5,O43731,P10619,O60476,O60762,Q9BUN8,Q9BT22,Q12907,P04844,Q13885,P61163,O95487,Q8IUR0 35 +Signaling by ptk6 0.3731121858246015 0.3680671685433114 0.7128231508046423 1.0 0.9060802633949224 13 P46108,Q07666,P61586 3 +Regulation of tp53 expression and degradation 0.3908175820667529 0.3635674747098662 0.7161810183644117 1.0 0.906306203508686 10 Q13315,P42345,P30154 3 +Fatty acyl coa biosynthesis 0.3656037437424113 0.3611913462784156 0.7179564107807213 1.0 0.9067869229934628 14 Q53GQ0,P50897 2 +Tysnd1 cleaves peroxisomal proteins 0.4445682983712353 0.3570835588810619 0.7210292523233881 1.0 0.9083681027038398 6 Q15067 1 +Diseases associated with glycosylation precursor biosynthesis 0.3890057603198945 0.3554102280210392 0.7222822875482109 1.0 0.9091349756739746 10 Q14376,P10619,P16278,Q99519 4 +Polo like kinase mediated events 0.3974005122075854 0.3470720227870792 0.7285372111956889 1.0 0.9099145349759984 8 O95067,Q5TKA1,P53350 3 +Diseases of mismatch repair mmr 0.4111467756054972 0.3397440133503705 0.7340493132883354 1.0 0.913354127909913 3 P52701,P20585 2 +Binding and uptake of ligands by scavenger receptors 0.4175851540441196 0.337377796382042 0.7358321204186669 1.0 0.9139604946397348 7 Q8WTV0 1 +Other interleukin signaling 0.4099464457492173 0.3354475560515372 0.7372874993259015 1.0 0.9139845693445324 3 Q13277 1 +Transcriptional regulation by e2f6 0.3782365535609653 0.3324212092267365 0.739571225614684 1.0 0.9145793158127248 11 Q9H9B1,Q15022,Q99496,P31350,Q9UBK9 5 +Activation of nima kinases nek9 nek6 nek7 0.4439518623885004 0.3264899253894462 0.7440537104503475 1.0 0.918512498202485 5 O95067,P53350 2 +Mapk targets nuclear events mediated by map kinases 0.3861818903138923 0.3203531013836327 0.7487006732743846 1.0 0.919299087722316 9 P30154,Q15418,P51812,Q14738 4 +Erk mapk targets 0.3861818903138923 0.3203531013836327 0.7487006732743846 1.0 0.919299087722316 9 P30154,Q15418,P51812,Q14738 4 +Mitotic prometaphase 0.2477791871223393 0.3196263990553537 0.7492515598020293 1.0 0.919299087722316 102 Q96GD4,Q8NBT2,O43805,P30154,O14777,P68371,Q9H6D7,P30153,P07900,Q15154,O43683,Q9BZD4,O75935,P07437,P04350,Q7L7X3,O95684,O94927,Q68CZ6,O95067,P41208,P49792,P14635,Q12769,Q9BW27,Q8NFH4,O15078,Q13885,P53350,P61163,Q16537,Q14738 32 +Signaling by erbb2 ecd mutants 0.4395161684097933 0.3115758231433942 0.7553629105223851 1.0 0.9243860075863708 5 Q16543 1 +Signaling by erbb2 in cancer 0.4395161684097933 0.3115758231433942 0.7553629105223851 1.0 0.9243860075863708 5 Q16543 1 +Platelet activation signaling and aggregation 0.2630155172263965 0.301568063229551 0.7629813569781847 1.0 0.9304811535835944 59 O43852,P07602,P52429,Q08380,P05067,P61586,Q9NZJ7,O94919,P13473,P46108,Q8NCG7,Q9NUQ9,Q9NTK5,Q8NBX0 14 +Apoptotic cleavage of cell adhesion proteins 0.4070768611752308 0.2979408612123418 0.7657483006307677 1.0 0.9329594701344468 7 P42574,Q16625,Q07157 3 +Activation of atr in response to replication stress 0.3130863615256795 0.2925208963674231 0.7698883852348541 1.0 0.9336402739475956 22 Q14566,Q13535,P40937,Q9Y619 4 +Dna damage reversal 0.4404553415061358 0.2918267375457143 0.7704191010252979 1.0 0.9336402739475956 4 Q8N3C0,Q9H1I8,Q6P6C2 3 +N glycan trimming in the er and calnexin calreticulin cycle 0.3378369977946416 0.2834088960372744 0.7768634097775535 1.0 0.9347526334319664 16 Q9UBV2,Q13438,Q9BUN8 3 +Transcriptional regulation by small rnas 0.2790221143037666 0.2830497266736311 0.7771387185463072 1.0 0.9347526334319664 35 Q12769,O15397,Q7Z3B4,Q99567,Q8NFH4,Q5SRE5,P30876,Q9BTX1,P35658,Q8N1F7 10 +Regulation of tp53 activity through methylation 0.4291296024109882 0.2777092432493282 0.7812355645176658 1.0 0.9354766969897022 5 Q13315 1 +Muscle contraction 0.2861752867006849 0.2771520224617192 0.7816633775697086 1.0 0.9354766969897022 30 P20020,Q9HD47,P16615,P08670,P04083 5 +Antiviral mechanism by ifn stimulated genes 0.2566695975199138 0.2686108100459641 0.7882291927266751 1.0 0.9379115430080818 48 Q99567,Q9BTX1,P46934 3 +Rhobtb2 gtpase cycle 0.3136748114037759 0.2638352747279665 0.7919068520135066 1.0 0.9405560338308568 19 Q16543,P62995,P07910,P07900,P38159 5 +Glyoxylate metabolism and glycine degradation 0.3445809484304986 0.2575539001271754 0.7967512119237474 1.0 0.9423436379081372 14 P23378,Q9NR77,P11177 3 +Heme biosynthesis 0.4116691386992938 0.2448011333000931 0.8066104163678087 1.0 0.948021535634638 6 Q7KZN9,P22830 2 +Ripk1 mediated regulated necrosis 0.3577454777210859 0.2435890193732554 0.8075491334467135 1.0 0.948021535634638 11 P49327,O00560,Q16543,P07900 4 +Met activates ptk2 signaling 0.424109748978407 0.2426575893750712 0.8082706643291775 1.0 0.948021535634638 4 Q9NWH9,P11047,P05556 3 +Carboxyterminal post translational modifications of tubulin 0.3906827790335377 0.2400608786381786 0.8102830618058885 1.0 0.9487340629540878 7 P04350,Q13885,P68371 3 +Chaperone mediated autophagy 0.3646265445250417 0.2343336920802481 0.8147259314748381 1.0 0.9487340629540878 9 P08670,Q9UBN7,P13473 3 +Interleukin 35 signalling 0.3787569302597148 0.2318949179565083 0.8166196318362855 1.0 0.9487340629540878 3 P42224,P27824 2 +Interleukin 27 signaling 0.3787569302597148 0.2318949179565083 0.8166196318362855 1.0 0.9487340629540878 3 P42224,P27824 2 +Interleukin 7 signaling 0.3787569302597126 0.2318949179565018 0.8166196318362906 1.0 0.9487340629540878 3 O00459,P51532 2 +Hemostasis 0.2396163252761277 0.231473763426823 0.8169467657613159 1.0 0.9487340629540878 130 P20020,Q92896,P16615,P30154,P53985,P35613,P68371,Q8NCG7,O43707,P30153,O43572,P07602,Q08380,P33176,O94919,P46108,Q9Y6I9,Q6YHK3,Q9Y496,Q6UXV4,P04350,O43852,P05067,P61586,P42785,Q9NZJ7,Q9NUQ9,Q9NSK0,Q8NBX0,P78310,P52429,Q07021,P13473,Q9UHQ9,Q13885,Q8IWA4,Q9NTK5,Q16537,Q14738 39 +Ros and rns production in phagocytes 0.3607677174434576 0.2199456325076914 0.8259134967684996 1.0 0.9528732166315232 9 Q9Y487 1 +G alpha q signalling events 0.3176516395440362 0.2129519405372308 0.831364448712006 1.0 0.9553778956098428 17 Q15418,P52429,P05067,P04083,Q8NCG7 5 +Diseases of dna repair 0.3492240575002456 0.2093832971284311 0.8341490307466812 1.0 0.9568977905557458 11 Q9UQ84 1 +Interferon signaling 0.2550245372274454 0.2076677876095119 0.8354883710894367 1.0 0.957655638998534 62 Q12769,P46934,Q7Z3B4,Q99567,Q8NFH4,P10321,P01889,P04439,P52294,Q5SRE5,Q9BTX1,Q8N1F7 12 +Neurotransmitter release cycle 0.3800759567630701 0.2051805608640053 0.8374310565301653 1.0 0.9583254020795322 7 P51649,O14936,O75915,Q13136,P80404,O94925 6 +Calnexin calreticulin cycle 0.355399517885987 0.2004768902051046 0.8411076300608149 1.0 0.9602321026750964 9 Q9UBV2,Q13438 2 +Apoptotic cleavage of cellular proteins 0.3006783609531521 0.1988613462790417 0.8423712067740203 1.0 0.9608615786242058 20 P42574,P51572,P49354,P08670,Q16625 5 +Beta oxidation of very long chain fatty acids 0.3947676442941871 0.1936716115404171 0.8464330216550731 1.0 0.9639362337008136 6 Q15067 1 +Citric acid cycle tca cycle 0.3007292646357734 0.1926198656567302 0.8472566857322859 1.0 0.9640961157808512 19 P48735 1 +Ion homeostasis 0.3396023914199418 0.1905460113295223 0.8488812917460302 1.0 0.9651664002043906 12 P20020,O43865,P16615 3 +Cytosolic iron sulfur cluster assembly 0.3917540734292136 0.185067774945809 0.8531758768363507 1.0 0.9684884651778688 6 O75027,P28340,P18074 3 +Regulation of mecp2 expression and activity 0.3272200818499143 0.180275783016875 0.8569360665413939 1.0 0.9704147591411773 14 Q9HCE1,Q14739 2 +Mitotic prophase 0.2523133433942249 0.1785374682181912 0.8583008984733194 1.0 0.9705686715811628 62 P30154,Q5SRE5,P42166,P35658,P30153,Q96GX5,Q7Z3B4,Q99567,P50402,P42695,O95067,P49792,Q9BTX1,Q8N1F7,P14635,Q92621,Q12769,Q8NFH4,P53350 19 +Copi mediated anterograde transport 0.2508102136066867 0.1760549044815111 0.8602508084794023 1.0 0.9705686715811628 57 P24390,P68371,P49755,Q08379,O15020,Q13190,Q9BVK6,Q15363,O95249,Q9UJW0,O75935,Q13813,P04350,O15498,Q9Y3B3,Q9BVA1,O43731,Q13885,P61163 19 +Aryl hydrocarbon receptor signalling 0.3592063028888335 0.175741521781729 0.860497013271887 1.0 0.9705686715811628 3 Q15185,P08238 2 +Regulation of tp53 activity through phosphorylation 0.2641420666752148 0.1752075656847047 0.8609165397316163 1.0 0.9705686715811628 36 P40937,P54646,Q13315,Q13535,Q9UQ84,Q92804 6 +Copi independent golgi to er retrograde traffic 0.2783621611029234 0.1713182359968409 0.8639735421855164 1.0 0.9721424784878498 28 Q8TD16,P04350,Q10472,Q9UJW0,O75935,Q13885,P61163 7 +Nuclear events kinase and transcription factor activation 0.3342640157391012 0.1698393434355029 0.8651364848067289 1.0 0.972675362599438 12 P30154,Q15418,P51812,Q14738 4 +Transcriptional activation of mitochondrial biogenesis 0.3181084827176824 0.1628534343955116 0.870633835233567 1.0 0.9778466717265988 15 P48735 1 +Insulin receptor recycling 0.3406797500639647 0.162233362729693 0.8711220881363109 1.0 0.9778466717265988 10 Q93050,Q9Y487 2 +Transferrin endocytosis and recycling 0.3338872047395469 0.1523214603774463 0.8789333994822204 1.0 0.9816291983273326 11 Q93050,Q9Y487 2 +Synthesis of pips at the er membrane 0.3492850889991316 0.1500607489319587 0.8807166870818488 1.0 0.9823646209268684 3 Q9NTJ5,P42356 2 +Mtor signalling 0.3233750371585255 0.1466089107334222 0.8834407199415906 1.0 0.983864250316066 13 P42345,P23588,P54646,P62753 4 +Lysosome vesicle biogenesis 0.3123814252068962 0.1389796088143627 0.8894662624652472 1.0 0.9872168456845378 15 P05067 1 +Mitotic telophase cytokinesis 0.3204695951936746 0.1356876673445569 0.8920681975807705 1.0 0.9872168456845378 13 Q9Y6X3 1 +Caspase activation via extrinsic apoptotic signalling pathway 0.3777970291354441 0.1348505574366467 0.8927300318168414 1.0 0.9872168456845378 5 P49327,Q9Y5V3 2 +Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.3777792497012713 0.1348087691481611 0.8927630723554005 1.0 0.9872168456845378 5 P30154,Q14738 2 +Depolymerisation of the nuclear lamina 0.3275485191054764 0.1305294569541567 0.8961475502220715 1.0 0.9881682412029742 11 P50402,P42166,P05771,P14635 4 +Acyl chain remodeling of cl 0.3407392597825522 0.129513951929804 0.8969509858858267 1.0 0.9881682412029742 3 Q6UWP7 1 +Fgfr2 alternative splicing 0.2983271500086976 0.1229499265907461 0.9021467498066178 1.0 0.989835975098863 17 P31943,P52597,P31483,Q01085 4 +Activation of nmda receptors and postsynaptic events 0.2721282488040451 0.1146727025685443 0.9087045513611104 1.0 0.9913872539060664 27 P04350,Q15418,P52292,O14936,P54646,P51812,Q14012,P68371,Q13885,Q9BVA1,Q14168 11 +Constitutive signaling by ligand responsive egfr cancer variants 0.368233093820721 0.1131847063079755 0.9098841203461064 1.0 0.9913872539060664 5 Q16543 1 +Constitutive signaling by egfrviii 0.368233093820721 0.1131847063079755 0.9098841203461064 1.0 0.9913872539060664 5 Q16543 1 +Signaling by egfr in cancer 0.368233093820721 0.1131847063079755 0.9098841203461064 1.0 0.9913872539060664 5 Q16543 1 +Activation of the pre replicative complex 0.2830750516816885 0.1088514257792599 0.9133203342370022 1.0 0.9926893533964684 20 Q14566,Q9Y619 2 +Transmission across chemical synapses 0.239936759036262 0.1087384244564003 0.9134099642297386 1.0 0.9926893533964684 48 P04350,Q15418,O14936,P54646,P05091,Q14168,Q13885,P21964 8 +Vitamin b5 pantothenate metabolism 0.3689038858525057 0.1070139495715879 0.9147779131487022 1.0 0.9928858734252451 4 Q9NRN7 1 +Transcriptional regulation by ventx 0.3014174114673155 0.0962617592044682 0.9233126817337636 1.0 0.9955947540872372 15 Q9UJX4,Q9UJX2,Q9H1A4,Q9HCE1,Q13042,P30260 6 +Caspase mediated cleavage of cytoskeletal proteins 0.339798488978368 0.0932139372565578 0.9257336022680598 1.0 0.9955947540872372 7 P42574,P08670 2 +Post chaperonin tubulin folding pathway 0.3177048126574523 0.0898587556113325 0.928399456761012 1.0 0.9955947540872372 10 P04350,Q13885,Q99426,P68371 4 +Disorders of transmembrane transporters 0.2346635823462242 0.0882241704177556 0.9296985070022116 1.0 0.9955947540872372 74 O14678,Q9UBV2,P49721,P53985,P35613,Q5SRE5,P35658,P11166,Q7Z3B4,Q99567,Q92530,P20618,O75477,Q9UL46,P28072,Q13438,Q9BTX1,Q8N1F7,Q12769,Q8NFH4,Q9BUN8 21 +Regulated necrosis 0.2942977089259093 0.0863193888781623 0.9312125259048908 1.0 0.9955947540872372 16 Q16543,O00560,O75955,P49327,P07900 5 +Synthesis of pips at the early endosome membrane 0.3494890510948951 0.0754933851367326 0.939822160415581 1.0 1.0 5 O00443,Q9BTU6,Q96PE3,Q99570 4 +Signaling by notch3 0.3284767640624439 0.0679467901180936 0.945827991662448 1.0 1.0 7 P67809 1 +Downregulation of erbb2 signaling 0.337952343101545 0.0597099905541048 0.952386614622827 1.0 1.0 6 Q16543,P07900 2 +Rsk activation 0.3402020747987785 0.0565925311702317 0.9548697842740042 1.0 1.0 4 Q15418 1 +Vxpx cargo targeting to cilium 0.3069830973837102 0.0564097243514967 0.9550154103797196 1.0 1.0 9 Q96KP1,Q9UPT5,Q92538 3 +Vegfr2 mediated vascular permeability 0.3060270169755137 0.0541679725570424 0.9568013374036172 1.0 1.0 9 P42345 1 +Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3010607062218902 0.0515632313275648 0.9588767174954492 1.0 1.0 11 Q9UJX4,Q9UJX2,Q9H1A4,Q13042,P30260 5 +Apc cdc20 mediated degradation of nek2a 0.3010607062218902 0.0515632313275648 0.9588767174954492 1.0 1.0 11 Q9UJX4,Q9UJX2,Q9H1A4,Q13042,P30260 5 +Josephin domain dubs 0.2990954187335969 0.0505480841586524 0.959685632734766 1.0 1.0 3 P54727,P54725 2 +Signaling by braf and raf1 fusions 0.2626207807919983 0.0495962174891666 0.9604441609307732 1.0 1.0 26 P51114 1 +Circadian clock 0.2934886031599445 0.0466385752351206 0.9628012868756743 1.0 1.0 13 P43490 1 +Er to golgi anterograde transport 0.2247153331554351 0.0301829553250207 0.9759211420188418 1.0 1.0 78 P24390,P68371,Q9HCU5,P49755,Q08379,O15020,Q13190,Q15363,Q9BVK6,O95249,P49257,Q9UJW0,O75935,Q13813,P04350,O15498,Q9Y3B3,Q9BVA1,Q96PC5,O43731,Q12907,Q13885,P61163,O95487,Q8IUR0 25 +Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.289980911014802 0.0214736024681574 0.9828678607854072 1.0 1.0 10 Q15418,Q14168 2 +Pre notch expression and processing 0.2833578396233375 0.0191818592365367 0.9846960291734306 1.0 1.0 13 Q9HCE1,P16615 2 +Pi metabolism 0.2616539426536654 0.0171437378142463 0.986321946301165 1.0 1.0 20 Q8TBX8,Q10713 2 +Rhoa gtpase cycle 0.2328526906924241 0.0159900363673917 0.9872423405071804 1.0 1.0 55 Q13190,P51572,O15173,Q8TAA9,Q07021,Q15904,P30519,P61586,Q92974,P49257,Q8NBN3,P28288,Q96HY6,P42166,Q14739 15 +Apoptotic execution phase 0.2458723532478158 0.0146983663886739 0.9882728226513986 1.0 1.0 31 P08670,P52294 2 +Mrna splicing 0.2270013233480718 0.008242136974484 0.9934238006167512 1.0 1.0 144 P55769,P61978,Q9BWJ5,P14866,P52756,P17844,P67809,Q14103,P51991,Q13151,P07910,Q15427,Q92733,P52597,O43390,P55795,P62995,P31943,P26368,P22626,P62316,P30876,Q9BUJ2,Q6P2Q9,P38159,Q00839,O95391,P35637,Q08211,Q9UHX1,Q01081,O75400 32 +Sting mediated induction of host immune responses 0.3024817518248224 0.008177962275009 0.9934750028929762 1.0 1.0 5 P78527,P49959,P12956,Q9UJV9 4 +Irf3 mediated induction of type i ifn 0.3024817518248224 0.008177962275009 0.9934750028929762 1.0 1.0 5 P78527,P49959,P12956,Q9UJV9 4 +Raf activation 0.2763409256090841 0.0021008928437969 0.9983237312691386 1.0 1.0 13 P30154,Q16537,P30153,Q14738 4 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b2bdd5d519c569ed5f7fed82068487f662309c2d --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of caspases through apoptosome mediated cleavage", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the phototransduction cascade", "Activation of the pre replicative complex", "Activation of the tfap2 ap 2 family of transcription factors", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pe", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via dependence receptors in the absence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Clec7a inflammasome pathway", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of particulate exogenous antigens phagosomes", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Dectin 2 family", "Defective cftr causes cystic fibrosis", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective lfng causes scdo3", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythrocytes take up carbon dioxide and release oxygen", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr activation", "Fcgr3a mediated il10 synthesis", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling by cbl mutants", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of cell death genes", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose catabolism", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 processing", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Ncam1 interactions", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h2 nr1h3 regulate gene expression to control bile acid homeostasis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Olfactory signaling pathway", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase 2 plateau phase", "Phase 3 rapid repolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt activation", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Ras signaling downstream of nf1 loss of function variants", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of fzd by ubiquitination", "Regulation of gene expression by hypoxia inducible factor", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rhotekin and rhophilins", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 and foxp3 control the development of regulatory t lymphocytes tregs", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in bcr signaling", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of keratinocytes", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx1 regulates transcription of genes involved in interleukin signaling", "Runx1 regulates transcription of genes involved in wnt signaling", "Runx2 regulates bone development", "Runx2 regulates chondrocyte maturation", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates immune response and cell migration", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scavenging of heme from plasma", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory perception of taste", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of immune response proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 24 hydroxycholesterol", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis of wybutosine at g37 of trna phe", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf receptor superfamily tnfsf members mediating non canonical nf kb pathway", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT4", "AGPAT5", "AGPS", "AGTPBP1", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "APIP", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAP1", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6IP5", "ARL8A", "ARMC8", "ARMCX3", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATM", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATR", "AURKA", "AURKB", "B3GALT6", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BARD1", "BAX", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCKDHB", "BCKDK", "BCR", "BCS1L", "BDH2", "BECN1", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BSG", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CAD", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC115", "CCDC22", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK9", "CDKAL1", "CENPF", "CENPU", "CEP250", "CEP290", "CEP97", "CERS1", "CERS2", "CETN2", "CFL1", "CHAC2", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHM", "CHMP5", "CHMP7", "CHORDC1", "CHTF18", "CHTF8", "CHUK", "CIAPIN1", "CIT", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN7", "CLINT1", "CLIP1", "CLNS1A", "CLTA", "CLTB", "CLTC", "CMAS", "CMBL", "CMPK1", "CNDP2", "CNN2", "CNOT1", "CNOT10", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "COASY", "COG5", "COG7", "COG8", "COLGALT1", "COMMD2", "COMMD7", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREBBP", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTC", "CWC22", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF16", "DCAF7", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DENND5B", "DERA", "DERL1", "DERL2", "DFFA", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHRS7B", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DR1", "DSC2", "DSE", "DSG2", "DSP", "DST", "DTL", "DTYMK", "DUS2", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD2", "EFTUD2", "EHD1", "EHHADH", "EHMT1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELMO2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESD", "ESPL1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETHE1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC7", "EXOC8", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EYA4", "EZR", "FABP5", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120B", "FAM49B", "FAM91A1", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FBXL18", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FKBP14", "FKBP4", "FKBP5", "FKBP8", "FKBP9", "FLAD1", "FLCN", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNTA", "FNTB", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUCA1", "FUCA2", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLUD1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNL3", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GTSE1", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUS1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILK", "IMMT", "IMP3", "IMP4", "IMPDH2", "INCENP", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS14", "INTS3", "INTS4", "INTS6", "INTS7", "INTS8", "INTS9", "IPO5", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRS4", "ISCA2", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LNPEP", "LPCAT1", "LPCAT4", "LRP1", "LRPPRC", "LRRC1", "LRRC41", "LRRC8A", "LRRFIP1", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "LYPLA2", "LZTFL1", "M6PR", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAN1A2", "MAN2A1", "MAN2B1", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MAPRE1", "MARC1", "MARC2", "MARCKS", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCRS1", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED4", "METAP2", "MFAP1", "MFGE8", "MFN1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU2", "MID1", "MIF", "MIGA1", "MINPP1", "MIPEP", "MLEC", "MMAB", "MMACHC", "MMS19", "MOCS1", "MOCS2", "MOCS3", "MOGS", "MORC2", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFR", "MTIF2", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO1E", "MYO5A", "MYO6", "NAA35", "NADK2", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCKAP1", "NCKIPSD", "NCL", "NCOR1", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEK9", "NELFB", "NELFCD", "NELFE", "NET1", "NEU1", "NF1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NLN", "NME1", "NME3", "NME7", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRP1", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT16", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PARS2", "PATL1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNT", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PEBP1", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPO", "POFUT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POR", "POU2F1", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPFIBP1", "PPIB", "PPID", "PPIE", "PPIH", "PPIL2", "PPIL4", "PPM1F", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUS1", "PUS7", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB36", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RABEP1", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAF1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RASAL2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDX", "REL", "RELA", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RGS10", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIOX2", "RIPK1", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP36", "RRP7A", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SATB2", "SC5D", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGK3", "SGPL1", "SGTA", "SH3GL1", "SH3RF1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIN3A", "SIPA1", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX18", "STX3", "STX5", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGT1", "SULT2A1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SYMPK", "SYNE2", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAOK1", "TAP1", "TAP2", "TAPBP", "TARS", "TARS2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFB2M", "TFG", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM7SF2", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM87A", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TNRC6A", "TOM1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPRKB", "TPX2", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC13", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIO", "TRIP12", "TRMT10C", "TRMT11", "TRMT61A", "TRMU", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TST", "TSTA3", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNL4A", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBR1", "UBR2", "UBR4", "UBTF", "UBXN1", "UBXN7", "UCHL5", "UCK2", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119B", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP32", "USP34", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "WAPL", "WARS", "WASF2", "WBP11", "WDCP", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR35", "WDR36", "WDR4", "WDR43", "WDR46", "WDR48", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WIPI2", "WLS", "WNK1", "WRAP53", "WTAP", "WWP2", "XAB2", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YKT6", "YME1L1", "YPEL5", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCRB1", "ZFYVE16", "ZMYM2", "ZNF512B", "ZNF638", "ZW10"], "leading_proteins": ["AASDHPPT", "ABAT", "ABCB1", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABHD10", "ABI1", "ACAD11", "ACAT2", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSL3", "ACTN4", "ACTR1A", "AGPAT5", "AHCYL1", "AKAP10", "ALDH2", "ALDH3A2", "ALDH5A1", "ALG1", "ALG11", "ALKBH5", "ANAPC1", "ANAPC5", "ANKLE2", "ANO6", "ANXA1", "APOO", "APOOL", "APP", "ARHGEF2", "ARL6IP5", "ASAH1", "ASCC2", "ASCC3", "ASNA1", "ATAD3B", "ATG9A", "ATM", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATR", "AURKA", "AURKB", "B3GALT6", "B4GALT3", "B4GAT1", "BAG6", "BAIAP2", "BCAP31", "BECN1", "BICD2", "BSG", "BUB1", "C19orf70", "C1QBP", "CALU", "CAMK1", "CAMK2G", "CANX", "CASK", "CASP3", "CCNB1", "CCNB2", "CD109", "CDC16", "CDC23", "CDC27", "CDC37", "CDK11B", "CDK4", "CEP290", "CERS1", "CERS2", "CETN2", "CHCHD3", "CKAP4", "CLCN7", "COMT", "COX15", "COX2", "COX4I1", "COX6B1", "CPD", "CPT2", "CRK", "CRTAP", "CSNK1A1", "CTNND1", "CTSA", "CXADR", "CYB5B", "CYB5R1", "CYC1", "CYFIP1", "CYP51A1", "DAGLB", "DCTN3", "DCTN4", "DDRGK1", "DDX20", "DDX41", "DDX5", "DERL1", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHRS7B", "DHX9", "DIABLO", "DNAJC11", "DOHH", "DOLPP1", "DPM1", "DSE", "ECE1", "ECSIT", "EHMT1", "EIF4B", "EMD", "ENDOD1", "EPHX1", "ERAP1", "ERAP2", "ERCC2", "ERLIN1", "ETFDH", "EXO1", "EXOC2", "EXOC7", "FADS2", "FAM49B", "FAR1", "FAR2", "FASN", "FDFT1", "FECH", "FGFR1OP", "FIP1L1", "FKBP14", "FLOT1", "FNTA", "FUCA1", "FUCA2", "FUS", "FXR1", "GAA", "GALE", "GALNT1", "GALNT2", "GALNT4", "GBA", "GBE1", "GBF1", "GDAP1", "GGCX", "GGH", "GLA", "GLB1", "GLDC", "GLG1", "GLS", "GLUD1", "GM2A", "GNAI1", "GNAI2", "GNPAT", "GNS", "GOLGA2", "GOLGA5", "GOLIM4", "GOSR1", "GPAA1", "GPD2", "GRB2", "GSTA4", "GUSB", "HACD3", "HADH", "HAUS3", "HAUS4", "HAUS5", "HDAC6", "HEBP2", "HEXA", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPR", "HNRNPU", "HNRNPUL1", "HS2ST1", "HSD17B12", "HSP90AA1", "HSP90AB1", "HSP90B1", "ICMT", "IDH1", "IDH2", "IFT52", "IMMT", "INPP4A", "IPO8", "ITGAV", "ITGB1", "ITM2C", "KDELR1", "KDELR3", "KDM1B", "KDSR", "KHDRBS1", "KHSRP", "KIF3A", "KIF5B", "KLC4", "KPNA1", "KPNA2", "LAMC1", "LAMP2", "LBR", "LCLAT1", "LETM1", "LGALS3BP", "LIN9", "LMAN1", "LMAN2", "LMF2", "LNPEP", "LPCAT1", "MAGED1", "MAGT1", "MAN1A2", "MAN2A1", "MASTL", "MAU2", "MBOAT7", "MCL1", "MCM6", "MFAP1", "MFN1", "MIA2", "MICU2", "MIGA1", "MIPEP", "MOV10", "MPP2", "MRE11", "MSH3", "MSH6", "MSMO1", "MTAP", "MTCH1", "MTOR", "MTR", "MTX1", "NAA35", "NAGLU", "NAMPT", "NBAS", "NCAPD3", "NCKAP1", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEDD4", "NEDD4L", "NEU1", "NLN", "NNT", "NPC1", "NPC2", "NRP1", "NSMCE2", "NT5C2", "NUCB1", "NUDT19", "NUF2", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP54", "NUP85", "NUP88", "NUP93", "OCLN", "OLA1", "ORC3", "OS9", "OSBP", "OSBPL8", "OSBPL9", "P3H1", "P4HA1", "PCM1", "PDHB", "PDK1", "PDK3", "PDSS1", "PGRMC1", "PGRMC2", "PHB2", "PI4K2A", "PI4KA", "PIGU", "PIK3C2A", "PIK3R2", "PIK3R4", "PIP4K2C", "PISD", "PITRM1", "PLA2G15", "PLD3", "PLD6", "PLK1", "PLOD3", "PMPCA", "PNPLA6", "PNPLA8", "POLD1", "POLR2B", "POLRMT", "POMGNT2", "PON2", "POR", "PPFIA1", "PPME1", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP2R5E", "PPT1", "PRCC", "PRCP", "PREB", "PRKAA2", "PRKCB", "PRKDC", "PRKRA", "PRMT5", "PRPF40A", "PRPF8", "PSAP", "PSMB1", "PSMB2", "PSMB6", "PSME2", "PSMF1", "PTDSS1", "PTGES2", "PTGES3", "PUF60", "PXMP2", "RAB24", "RAC1", "RAD23A", "RAD23B", "RALA", "RANBP2", "RANGRF", "RBM5", "RBMX", "RFC5", "RHOA", "RINT1", "RNASET2", "RNF2", "RPN2", "RPS6", "RPS6KA1", "RPS6KA3", "RRM2", "RTN3", "SACM1L", "SAMM50", "SC5D", "SCARB1", "SCCPDH", "SCD", "SDCBP", "SDHB", "SEC11A", "SEC24B", "SEL1L", "SF3B4", "SF3B5", "SGPL1", "SIGMAR1", "SLC12A2", "SLC16A1", "SLC25A10", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC2A1", "SLC35B2", "SLC39A14", "SLC4A7", "SLC7A1", "SLTM", "SLU7", "SMARCA4", "SMN1*", "SMPD4", "SNRPD2", "SNU13", "SOAT1", "SPC24", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRPRB", "SSNA1", "SSR1", "STARD3", "STAT1", "STT3A", "STX18", "STX3", "STX5", "STXBP3", "SULT2A1", "SURF4", "SUZ12", "TAF15", "TAOK1", "TAP1", "TAP2", "TBCB", "TDRKH", "TECR", "TEX264", "THOC1", "TIA1", "TIAL1", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TM7SF2", "TMED10", "TMED2", "TMED7", "TMED9", "TMEM87A", "TMPO", "TNPO1", "TOMM22", "TOMM5", "TPP1", "TRA2B", "TRAPPC5", "TRIM27", "TRMU", "TSN", "TSPO", "TTC26", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TYSND1", "U2AF1", "U2AF2", "UNC119B", "UQCR10", "UQCRQ", "UXT", "VANGL1", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS33B", "WDR35", "WDR6", "WFS1", "XPO5", "XRCC6", "YBX1", "YKT6"]} \ No newline at end of file diff --git a/msigdb_wp/advanced/idx2term.json b/msigdb_wp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..34d884dc89af217779141a7869d5d3d9050134ad --- /dev/null +++ b/msigdb_wp/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Sphingolipid pathway", "1": "Electron transport chain oxphos system in mitochondria", "2": "Nonalcoholic fatty liver disease", "3": "Sphingolipid metabolism in senescence", "4": "Sphingolipid metabolism integrated pathway", "5": "Sphingolipid metabolism overview", "6": "Degradation pathway of sphingolipids including diseases", "7": "Mitochondrial complex iv assembly", "8": "Mitochondrial complex i assembly model oxphos system", "9": "Ferroptosis"} \ No newline at end of file diff --git a/msigdb_wp/advanced/plot_0.png b/msigdb_wp/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..35e68ec3acdf9f9ea2fb0cf244b1b9db99510853 --- /dev/null +++ b/msigdb_wp/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1a3d24c0ee9cc7c7ca4bfa89a281cb4960a9df6e06a374f8dbe33ec464477338 +size 191802 diff --git a/msigdb_wp/advanced/plot_1.png b/msigdb_wp/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..8a0b9546f5c07d770a62751943fe7f2bc97e6e56 --- /dev/null +++ b/msigdb_wp/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4c5de1a77bd410399eec6e1383fe871ac2333ce047c6d66d9f457b1f5e104519 +size 212919 diff --git a/msigdb_wp/advanced/plot_2.png b/msigdb_wp/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..5428c28c143358431621ea8c9c5068aa39e55b6d --- /dev/null +++ b/msigdb_wp/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0fff184b627e607c3e9bc6315e1d3a655a4753d6b26fb67cad16e554a4842aff +size 212726 diff --git a/msigdb_wp/advanced/plot_3.png b/msigdb_wp/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..598f051639550011d0ffe17fc073d3ba0bf1a008 --- /dev/null +++ b/msigdb_wp/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e23a5adfd6c3d9ed99fb3eb0088be1fc8013dec4cddb0caef461f6a342b7d184 +size 202822 diff --git a/msigdb_wp/advanced/plot_4.png b/msigdb_wp/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..fd3c7f0258e316fc051bf1b5c1a61b5468c62537 --- /dev/null +++ b/msigdb_wp/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a6eb535554f42c7c6b235d57f2eed8ed96a54739c74eb8438c996e85a967f460 +size 192312 diff --git a/msigdb_wp/advanced/plot_5.png b/msigdb_wp/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..b82230ca23e31e96f39a08355168d50000a59dc0 --- /dev/null +++ b/msigdb_wp/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1d94692d589d05730f41bb0db6e029f5390643c1163a4ad21a59a7e7fd860237 +size 191180 diff --git a/msigdb_wp/advanced/plot_6.png b/msigdb_wp/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..d268c8a1e795ad0f219c2eac016cfef091a36a92 --- /dev/null +++ b/msigdb_wp/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ed69c86bf4dbfff94b966941bf2e23e4accb286b34ffcf868e60befe92daccfe +size 197504 diff --git a/msigdb_wp/advanced/plot_7.png b/msigdb_wp/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..c2665ede9fae2035c2040052f35a7d3f9a6ab66c --- /dev/null +++ b/msigdb_wp/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1f9f17ec6458f1e184a0ccacc34388da95f056f13ba72f2109092c94588d48c8 +size 198906 diff --git a/msigdb_wp/advanced/plot_8.png b/msigdb_wp/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..76c281294806d65f9c3630770f829da3b6c92f3d --- /dev/null +++ b/msigdb_wp/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:727d0c122ed4c88e7dff771240dee8ce7472d28fcacc6adb7b3a7b444f3de0dd +size 206566 diff --git a/msigdb_wp/advanced/plot_9.png b/msigdb_wp/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..bdc41a66ffdf24a4514c4a55bd0daed138da0fb5 --- /dev/null +++ b/msigdb_wp/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c363fff78716f6fa6160d6d6d9e536e362b12668aa6205b75df40bbfff69adc9 +size 203893 diff --git a/msigdb_wp/basic/idx2term.json b/msigdb_wp/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..08c3db9f8a462e2775780c5e84756833cdc24bce --- /dev/null +++ b/msigdb_wp/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Sphingolipid pathway", "1": "Electron transport chain oxphos system in mitochondria", "2": "Nonalcoholic fatty liver disease", "3": "Sphingolipid metabolism in senescence", "4": "Sphingolipid metabolism integrated pathway", "5": "Sphingolipid metabolism overview", "6": "Degradation pathway of sphingolipids including diseases", "7": "Mitochondrial complex iv assembly", "8": "Mitochondrial complex i assembly model oxphos system", "9": "Ferroptosis", "10": "Cholesterol metabolism with bloch and kandutschrussell pathways", "11": "Circadian rhythm genes", "12": "Metapathway biotransformation phase i and ii", "13": "Mrna processing", "14": "Oxidative phosphorylation", "15": "7oxoc and 7betahc pathways", "16": "Ebola virus infection in host", "17": "Omega9 fatty acid synthesis", "18": "Cohesin complex cornelia de lange syndrome", "19": "Alzheimers disease and mirna effects", "20": "Mecp2 and associated rett syndrome", "21": "Alzheimers disease", "22": "Ppar signaling pathway", "23": "Pi3kakt signaling pathway", "24": "Angiopoietinlike protein 8 regulatory pathway", "25": "Rett syndrome causing genes", "26": "Mitochondrial long chain fatty acid betaoxidation", "27": "Joubert syndrome", "28": "Orexin receptor pathway", "29": "Glycogen synthesis and degradation", "30": "Chromosomal and microsatellite instability in colorectal cancer", "31": "Genes controlling nephrogenesis", "32": "Smc1smc3 role in dna damage cornelia de lange syndrome", "33": "Focal adhesion pi3kaktmtorsignaling pathway"} \ No newline at end of file diff --git a/msigdb_wp/basic/plot_0.png b/msigdb_wp/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..219cb99d869212cd4f85023c65b32368741e88d4 --- /dev/null +++ b/msigdb_wp/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1cce231dad6cb135ddfe43cb62445a2fcd838f744a5c1c9d91a56b840ec7b06b +size 142286 diff --git a/msigdb_wp/basic/plot_1.png b/msigdb_wp/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..7e3a78e3840be30a9dbdce32928e246113f8a87f --- /dev/null +++ b/msigdb_wp/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1cff079797f04cdb010b0cc5e287e4782eb569863f1404ab3e6ab54c8db210eb +size 141880 diff --git a/msigdb_wp/basic/plot_10.png b/msigdb_wp/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..66a0129de1a3da8b6e32dc301f1f3c69c59e9af9 --- /dev/null +++ b/msigdb_wp/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:11fb30207e8180627a4e9ef57fcdec4454c37967d7eabc625b394b576a07241e +size 137054 diff --git a/msigdb_wp/basic/plot_11.png b/msigdb_wp/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..1cf9f7c0866d73867b4eeabbc7f11440f24f5f91 --- /dev/null +++ b/msigdb_wp/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0549bf7fa78332fdb85346976758f13fdef1fff717a624c69195647e7b73bb3 +size 143322 diff --git a/msigdb_wp/basic/plot_12.png b/msigdb_wp/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..269f9ff43b50737e02ed742a7b52fc8a3dbb4afb --- /dev/null +++ b/msigdb_wp/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9a5fef33ed078dd1fd1cd6756f8b574909314932b7dc874495a74db0b6d24f86 +size 142902 diff --git a/msigdb_wp/basic/plot_13.png b/msigdb_wp/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..6574a1acc020365490bf1bc268f12bb8ed4b07d3 --- /dev/null +++ b/msigdb_wp/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e6e5e4d1676ff0fbac9b25591cf00831ea9d66a3444b82aa93f45e9e5bc64054 +size 143322 diff --git a/msigdb_wp/basic/plot_14.png b/msigdb_wp/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..e7d250684872d480329dd98f68d84e39e9a9d026 --- /dev/null +++ b/msigdb_wp/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6c0551d64b9660cca9bb34ac3ae4a95947d202107474d4a29f4caa75382e0b20 +size 144251 diff --git a/msigdb_wp/basic/plot_15.png b/msigdb_wp/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..922eed72ee9f8af5832251a05e599ecfe17f42ec --- /dev/null +++ b/msigdb_wp/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cdd2d8d99b0c145d545dfa95e9d0214265a38bb884df498a29b6e5e8bc003baa +size 139171 diff --git a/msigdb_wp/basic/plot_16.png b/msigdb_wp/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..b5b79cbdd78e90f269446bbc79d551b5cae04229 --- /dev/null +++ b/msigdb_wp/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a9aac692e26c842e52062b77154036cf72f246454e1e5c97de2ae1630c2dc4c8 +size 144736 diff --git a/msigdb_wp/basic/plot_17.png b/msigdb_wp/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..1bf91228ede7ceded05710fa8dc18e8e36cece5e --- /dev/null +++ b/msigdb_wp/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:97e934c5010210dca92ec6cfec1c202aab728c36020c7885c744c4a9c32e29d5 +size 126454 diff --git a/msigdb_wp/basic/plot_18.png b/msigdb_wp/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..4e453b222baed814e3ebbe1ebda96c2f7d1ca26e --- /dev/null +++ b/msigdb_wp/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:377d18b4a2a2d8990efd8cdbe3275e9a0fc2b4ad1066a821e1f60913d6474b98 +size 152151 diff --git a/msigdb_wp/basic/plot_19.png b/msigdb_wp/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..55d50304602bcafbcfe7d57b26dd4c8296d9a626 --- /dev/null +++ b/msigdb_wp/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b7d5fb3177b75b69d4c18c8727d742df2bab0b7ad8dc53537fac3cad0939ea2a +size 155739 diff --git a/msigdb_wp/basic/plot_2.png b/msigdb_wp/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..46cd040d3cfa7a20f6945b39baf29dda02271bef --- /dev/null +++ b/msigdb_wp/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ae0801365aa162cb4b5c94440fde652ca18a4a03df97ab91d8bfe23bc41a492a +size 150776 diff --git a/msigdb_wp/basic/plot_20.png b/msigdb_wp/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..912b40024fa6254cc243d2057e8fe4858bfb3a4b --- /dev/null +++ b/msigdb_wp/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:231adc364a090090f000424eb1b29a484a13daaa0514a257101eb91cabb4c3c7 +size 151891 diff --git a/msigdb_wp/basic/plot_21.png b/msigdb_wp/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..6327d1ba5915a4e98dc4820413d07ed00755497c --- /dev/null +++ b/msigdb_wp/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3809ffb19bf8b122076ff9b7cebcb171d29687b319eaf130b6c8f87e2e40fd9e +size 146805 diff --git a/msigdb_wp/basic/plot_22.png b/msigdb_wp/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..5a94fa45f27081f30fc531e0c66330058feab5c4 --- /dev/null +++ b/msigdb_wp/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:747d92093c8166fe820d69a34898a19a1287d5d8d74712e685f4400f456af0ef +size 143115 diff --git a/msigdb_wp/basic/plot_23.png b/msigdb_wp/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..db0a1aeb00bab1b859a3afbe446e2b84a8531c65 --- /dev/null +++ b/msigdb_wp/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7c6a4d57fef523c368412a5009ffac16360d3c859d27c90d3dc485701b0de8f0 +size 151663 diff --git a/msigdb_wp/basic/plot_24.png b/msigdb_wp/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..cbcddee21b0c63fc60d88c86e7e51c8322cf125b --- /dev/null +++ b/msigdb_wp/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6a43ca0aa9ea750689ac143913eba4ceedc00591dcc732ebc8991c7382bcb97b +size 155648 diff --git a/msigdb_wp/basic/plot_25.png b/msigdb_wp/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..a76d0e320d191104517227ada796ff8e8612c82f --- /dev/null +++ b/msigdb_wp/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:155884cb917a4c12dcef9e6bc3425d5b9da24df7189871cbf8501479ccf6a887 +size 150867 diff --git a/msigdb_wp/basic/plot_26.png b/msigdb_wp/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..0f6f77fc043c842d64d48bc706fe43abc2a1fb54 --- /dev/null +++ b/msigdb_wp/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2702d7577759c9db22e5d4210a7ddf32e872da86e4bfaa2d63d5f48fd3fb80e7 +size 154292 diff --git a/msigdb_wp/basic/plot_27.png b/msigdb_wp/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..06d80f9f49509958c47919f748466182d20d843c --- /dev/null +++ b/msigdb_wp/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:80da75944958a6dfa0cd0b5460c63857ebb394dae63976fe37cd10e7574631db +size 149700 diff --git a/msigdb_wp/basic/plot_28.png b/msigdb_wp/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..4bee04177b31f6b7760fda465b71bc7c7342c729 --- /dev/null +++ b/msigdb_wp/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d2dd5d398b432616b6fa9374e86462e46788b337396cbcb93a98db027544aeec +size 149657 diff --git a/msigdb_wp/basic/plot_29.png b/msigdb_wp/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..49b74e6de91e82437b2edc09452a10e0b1dec994 --- /dev/null +++ b/msigdb_wp/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:80cf0ba37fa712ca194cf2d419dea368cf9d85fd081b5a5612b710e739eb4538 +size 158298 diff --git a/msigdb_wp/basic/plot_3.png b/msigdb_wp/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..d0419ed33892592b9165ac6023c4e142f800396b --- /dev/null +++ b/msigdb_wp/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:72be25ea400acc05a7d992ea66d59b5f39f55e1345d9dd0fb1ab3b26953627be +size 143852 diff --git a/msigdb_wp/basic/plot_30.png b/msigdb_wp/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..cbdea2ef82af885a495722ecb8c1a74f60fab9fb --- /dev/null +++ b/msigdb_wp/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d70ce8ea6493cc28d960a10bafe9008d093745f8e2aa6cc8e3c7f8d04cea2d2c +size 153952 diff --git a/msigdb_wp/basic/plot_31.png b/msigdb_wp/basic/plot_31.png new file mode 100644 index 0000000000000000000000000000000000000000..2d667acbc6cfb93d41780a040327d2621b6acce0 --- /dev/null +++ b/msigdb_wp/basic/plot_31.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a056f7e4d88b3f82e5aa8ada5a44f352679be597db00cebe9b6a138f7563e637 +size 149777 diff --git a/msigdb_wp/basic/plot_32.png b/msigdb_wp/basic/plot_32.png new file mode 100644 index 0000000000000000000000000000000000000000..a63fa3a0605d17315eebaed211fef1dda0d0dd7e --- /dev/null +++ b/msigdb_wp/basic/plot_32.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:abab011b37fd17c99fcdc9a572441822ddeaf48dfd7b45234870491f4edd13fb +size 158056 diff --git a/msigdb_wp/basic/plot_33.png b/msigdb_wp/basic/plot_33.png new file mode 100644 index 0000000000000000000000000000000000000000..014d38eefe14ebd73b800bb9830d913da1908d6e --- /dev/null +++ b/msigdb_wp/basic/plot_33.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5f05d0183812764dbaa13004a440f77c83b5db3195b99f7ba63eb31a7d8fb9e8 +size 156947 diff --git a/msigdb_wp/basic/plot_4.png b/msigdb_wp/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..6caab0d53ee7b662d0e858a5c0a65ea88fd886e2 --- /dev/null +++ b/msigdb_wp/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a8120967c5daee9e2c49496517017a9aae527b0f3266c77cffa275ecb95be299 +size 143508 diff --git a/msigdb_wp/basic/plot_5.png b/msigdb_wp/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..1d19485702abbf05c78b1ca5330db75c9f5bf4b4 --- /dev/null +++ b/msigdb_wp/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:856aa2746000dd5402242b9394931c3343d66ff6fc329f331d1f56043303661e +size 141495 diff --git a/msigdb_wp/basic/plot_6.png b/msigdb_wp/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..a27a7eae7899928fc5e46c4f98b1d1e28685a191 --- /dev/null +++ b/msigdb_wp/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0825fa1b3b715e1fb7cb3cd09c351ac60a26f72b681c794d33e6a09e3a0c1224 +size 146098 diff --git a/msigdb_wp/basic/plot_7.png b/msigdb_wp/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..a83fc9058405ef3b17640879ff7faf188b06e49e --- /dev/null +++ b/msigdb_wp/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba9d2a6f20a906b7cb89b6a70e318a042ca77b1026d7b7fb825a418f73b52371 +size 139100 diff --git a/msigdb_wp/basic/plot_8.png b/msigdb_wp/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..87ff6c7556183c51e96bbff91229f8aa305f0ff2 --- /dev/null +++ b/msigdb_wp/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:606c0380d14932d43a5eb3be9175e220c1943c2e7694c9f755b519eefb03e79d +size 144154 diff --git a/msigdb_wp/basic/plot_9.png b/msigdb_wp/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..9a7d35e29782508fb413e4d3fe831bd3272f480b --- /dev/null +++ b/msigdb_wp/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:799db3f9bbe912bab35b499d6f828d856ecc19a7f399363baaea6f693e97fa21 +size 128590 diff --git a/msigdb_wp/consensus.joblib b/msigdb_wp/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3a700d28b05cca21647cdf8d2d93c35a433dadee --- /dev/null +++ b/msigdb_wp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:62efd2f6f06278bdaaeba5fbe9345ba774573e5fae6b2548acf0ad54b87ee5a2 +size 134101 diff --git a/msigdb_wp/df_merge.tsv b/msigdb_wp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2e1e30f17102c71528f9535cc49c6f4464a2430d --- /dev/null +++ b/msigdb_wp/df_merge.tsv @@ -0,0 +1,18 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Sphingolipid pathway 6 8 2.906129076627265 0.0036593046418502 4.274271844660194 9.393203883495143 1.2258474538683668 0.1888473674707098 2.02173101931241 1.3620203536909472 1.3696572221543342 0.2416569853225122 0.0002934449453622 0.1026081339138497 0.0193632099375005 0.0157252402213966 5.564378317152988e-05 +Electron transport chain oxphos system in mitochondria 22 52 2.656232500517287 0.0079019113909717 17.57766990291262 50.45631067961165 1.00621396752225 0.3125021459260491 7.648293572467493 4.538458527560961 1.9412236823915887 0.3642771965747766 0.0009680706738517 0.0099608681798937 0.0002603673390021 0.0003661685145557 2.9365621493531424e-05 +Nonalcoholic fatty liver disease 14 55 2.5801094142983283 0.0098769015904136 14.446601941747574 49.78883495145631 0.8140299356769594 0.4039994838731682 5.918094936421778 5.382150615191258 1.5259550974793896 0.3817978315095583 0.0087397653900743 0.1267011687502946 0.0078713338334775 0.0036815410662345 0.0011536154086236 +Sphingolipid metabolism in senescence 6 13 2.4706012568607707 0.0134886126261075 4.349514563106796 11.679611650485436 1.1898351622318797 0.2087194733713789 1.8732078185138223 1.4259290429724831 1.4063103725171229 0.2533781048666968 0.0003664619465316 0.0055832614279084 0.0210734332562196 0.017764157863851 7.666164058302006e-05 +Glycosaminoglycan degradation 4 6 2.425806058360533 0.0152744304345 3.407766990291262 5.864077669902913 0.1350713234786387 0.1703873780123549 1.3379225542760151 0.7043353086258667 1.932540087143412 0.2532951180616937 1.1107568426286228e-05 0.0573151884822011 0.0058956460302812 0.0026887292270871 0.0001590313802548 +Sphingolipid metabolism integrated pathway 6 7 2.4166612076335725 0.015663588529609 4.058252427184466 8.101941747572816 1.3056837288293504 0.1731905617886817 2.1182299017960826 1.603786816240382 1.4154175704443392 0.233855234687812 0.0016623787157526 1.0 0.1709159600444602 0.0773660358903978 0.0002026911007435 +Sphingolipid metabolism overview 6 7 2.4166612076335725 0.015663588529609 4.0 7.951456310679611 1.305604070038762 0.1692072490812911 2.0060587839493125 1.5113078035984122 1.4254327231792938 0.2283290755268721 0.0010667446002337 1.0 0.1543818096433915 0.0635022977163126 0.0001004910149917 +Statin inhibition of cholesterol production 3 5 2.392238309500508 0.0167459652529595 2.0315533980582523 5.029126213592233 1.044092701346018 0.2144191485801186 1.2890406286437517 1.2084356467042294 1.2621579412510306 0.2395890160394713 0.0004793920471104 1.0 1.0 0.0042908003473226 0.0037486095651754 +Degradation pathway of sphingolipids including diseases 5 8 2.380568656159129 0.0172859395364388 3.645631067961165 6.432038834951456 0.0687547082162972 0.1728701573933007 1.3368036576958324 0.5554170290527195 1.9109030412897592 0.2451148181788838 6.741537110755754e-05 0.0432957136582515 0.0032780640178306 0.0190953097419897 2.858966188275996e-05 +Influence of laminopathies on wnt signaling 4 9 2.2698548768045783 0.023216389687207 2.929611650485437 10.199029126213592 1.172665957836072 0.274405530989148 1.5096443497648335 1.3031697834850824 0.8784257604250459 0.2713478851839423 0.2041646260338405 0.1373006943976843 0.0346664630686661 0.1658780833937837 0.0557230881301947 +Mitochondrial complex iv assembly 5 12 2.251392490152278 0.0243606893630727 4.645631067961165 11.985436893203884 1.036764412652062 0.2236438909453165 2.399566170297607 1.9080263664188637 1.5325215618909758 0.2795558816325345 0.068468596160163 0.0119629297909749 0.004393919895815 0.0494008625159685 0.0231294135439989 +Familial partial lipodystrophy fpld 1 7 2.1647959443799767 0.0304033155455394 2.7354368932038833 7.351941747572815 1.0487704575374006 0.2220749325398317 1.64741826657551 0.7567951823729889 1.2080189526980365 0.2461617416466816 0.1155282698604689 0.0981765691424607 0.0177148463510605 0.0920739634299925 0.2722934148112151 +Mitochondrial complex i assembly model oxphos system 13 27 2.074544087685542 0.0380288086622973 8.808252427184467 26.563106796116504 0.7827212026364002 0.3851038550171766 4.050605834390814 3.9632288075289823 1.2210776523685654 0.3331428769936953 0.0170604140358183 0.0286799036387023 0.0158208073938894 0.0424139427802885 0.0002346698535802 +Ccl18 signaling pathway 4 11 2.0462817594255656 0.0407286572753 3.145631067961165 9.468446601941748 0.7120304545820841 0.4102816521154631 1.5448490483978532 1.266243781864224 0.905865942202216 0.3015635802046986 0.0283422290577001 0.1114073342812727 0.2108642126213972 0.1154739846724814 0.0052582215982291 +Ferroptosis 6 23 2.046146351092095 0.0407419738246728 6.247572815533981 23.589805825242717 0.9586016481897424 0.3324276931898122 2.8577723913591164 2.1450310521583007 1.2134257594151 0.3161491716459103 0.0135540738761942 0.2222355866483168 0.0891217330395956 0.0078507588763973 0.0111707611872444 +Cytosine methylation 1 5 2.028662694345332 0.0424926581058779 2.0533980582524274 4.839805825242719 -0.0649747594084269 0.3077365108683944 1.3517565367896365 0.4045469252427314 1.4549970578233429 0.2999126289601936 0.0246179943383446 0.0008300469730069 0.0032780640178306 0.0190953097419897 0.0677640175569944 +Allograft rejection 4 10 2.02268716820218 0.0431054106848454 3.3300970873786406 9.83980582524272 0.7953176037476221 0.3759733848734315 1.6481136585050014 1.3214319833302084 0.931941180031962 0.288328422601957 0.2041646260338405 1.0 1.0 0.1658780833937837 0.0138780941766985 diff --git a/msigdb_wp/metrics.json b/msigdb_wp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b14561636d4f8de1da7646c64e6a6f7f38cde2bc --- /dev/null +++ b/msigdb_wp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 607, + "title": "Average number of proteins per term", + "value": 11.841845140032948 +} \ No newline at end of file diff --git a/msigdb_wp/paths.json b/msigdb_wp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..acee770906c36709e49a3a7771a4d7e04086bede --- /dev/null +++ b/msigdb_wp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_wp/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b30fec574343c5fd9bc0456f0c4704461590f13a --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,158 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Drug induction of bile acid pathway 0.9533255542590436 3.205466865912767 0.0013484357066517 0.559150978999193 0.0357895067960052 2 Q06520 1 +Sphingolipid pathway 0.906250931605274 2.906129076627265 0.0036593046418502 0.8919619586485641 0.0653293505177386 8 Q06136,O15269,O95470,Q13510,Q96G23,P04062 6 +Nuclear receptors in lipid metabolism and toxicity 0.8363477246207576 2.670897679319561 0.0075648702711454 0.9900415398442364 0.1020416945463403 2 P08183 1 +Electron transport chain oxphos system in mitochondria 0.4617875594979634 2.656232500517287 0.0079019113909717 0.9918969216166574 0.1020523449855286 52 P51970,P24539,Q7KZN9,O95168,O43676,O14949,P00403,O75306,P12236,P06576,O75438,O75964,P21912,P14406,Q9Y6M9,P03886,Q9UDW1,P13073,P12235,P56385,O96000,P14854 22 +Nonalcoholic fatty liver disease 0.4518266800157361 2.5801094142983283 0.0098769015904136 0.997582649239552 0.1197135790326001 55 P14406,P51970,Q9Y6M9,Q86Y39,P08574,Q9UDW1,P54646,P14854,P13073,O43676,O14949,Q96GC9,P00403,Q9P0J0 14 +Sphingolipid metabolism in senescence 0.7315677982185762 2.4706012568607707 0.0134886126261075 0.9997369875267204 0.1387726756618185 13 Q06136,O15269,P16278,Q13510,Q96G23,P04062 6 +Glycosaminoglycan degradation 0.9085921666625288 2.425806058360533 0.0152744304345 0.9999124339968896 0.1458116296513383 6 P06865,P16278,P15586,P54802 4 +Sphingolipid metabolism integrated pathway 0.8556821501606859 2.4166612076335725 0.015663588529609 0.9999311133515962 0.1458116296513383 7 Q06136,O15269,O15270,O95470,Q13510,Q96G23 6 +Sphingolipid metabolism overview 0.8556821501606859 2.4166612076335725 0.015663588529609 0.9999311133515962 0.1458116296513383 7 Q06136,O15269,O15270,O95470,Q13510,Q96G23 6 +Metabolism of spingolipids in er and golgi apparatus 0.8663554128975715 2.412252159715106 0.015854312284989 0.9999387576194108 0.1458116296513383 3 Q06136,O95470 2 +Statin inhibition of cholesterol production 0.9242098627410708 2.392238309500508 0.0167459652529595 0.9999646733481282 0.1477000997452964 5 Q8WTV0,Q14534,P37268 3 +Degradation pathway of sphingolipids including diseases 0.7963813999611581 2.380568656159129 0.0172859395364388 0.9999746900012968 0.1477000997452964 8 P17900,P16278,Q99519,P06865,P06280 5 +Liver x receptor pathway 0.7686697782963843 2.345931711440021 0.0189795844812736 0.9999911167163166 0.1477000997452964 2 O00767 1 +Pkcgamma calcium signaling pathway in ataxia 0.7578763127187731 2.2930190005170483 0.0218469110755461 0.9999984970440456 0.1599217642067844 2 Q15118 1 +Vitamin d metabolism 0.8383941677862619 2.28811450606634 0.0221308536958317 0.9999987398817426 0.1599217642067844 3 P04062 1 +Influence of laminopathies on wnt signaling 0.7593280875337666 2.2698548768045783 0.023216389687207 0.9999993578937948 0.1651450939854823 9 O75844,O60725,P48729,P50402 4 +Mitochondrial complex iv assembly 0.7092093019574338 2.251392490152278 0.0243606893630727 0.9999996847904008 0.1699648096940825 12 P14406,P14854,P13073,Q9Y2R0,P00403 5 +Familial partial lipodystrophy fpld 0.8014063159758081 2.1647959443799767 0.0304033155455394 0.9999999927421012 0.194261184590973 7 O75844 1 +Proteoglycan biosynthesis 0.7955450864949265 2.09471342907618 0.036196474736923 0.9999999998090032 0.2125397283172619 3 Q8TB61 1 +Mitochondrial complex i assembly model oxphos system 0.5136176242153412 2.074544087685542 0.0380288086622973 0.9999999999398308 0.2142129103654418 27 O75306,P51970,Q9Y6M9,Q9NPL8,O96000,P03886,O75438,Q96CU9,O95168,O43676,Q7L592,Q9BQ95,Q9P0J0 13 +Ccl18 signaling pathway 0.6875616639154563 2.0462817594255656 0.0407286572753 0.9999999999890736 0.2142129103654418 11 P08670,P00403,Q96GC9,Q86UE4 4 +Ferroptosis 0.540575473405309 2.046146351092095 0.0407419738246728 0.9999999999891654 0.2142129103654418 23 P37268,P16435,P45880,Q9Y277,P09601,Q15043 6 +Cytosine methylation 0.8387043988841123 2.028662694345332 0.0424926581058779 0.9999999999964252 0.2142129103654418 5 O75874 1 +Allograft rejection 0.6976321417140958 2.0226871682021796 0.0431054106848454 0.9999999999975762 0.2142129103654418 10 P08183,P08670,P04439,P01889 4 +Interactions between loxl4 and oxidative stress pathway 0.7676347728845508 1.966738705385929 0.0492133422330254 0.9999999999999504 0.2246894325370356 3 Q9BQ95 1 +Oxidation by cytochrome p450 0.8011889797674446 1.9534735825784315 0.0507635046055283 0.9999999999999816 0.2246894325370356 6 Q16850,O43169,P16435 3 +Type i collagen synthesis in the context of osteogenesis imperfecta 0.6527280923356977 1.932747785478509 0.0532672754201948 0.9999999999999964 0.2318454727610562 12 O75718,Q32P28,P13674,Q96AY3 4 +1q211 copy number variation syndrome 0.6941150897030616 1.931077893230337 0.0534734204061744 0.9999999999999968 0.2318454727610562 9 P54646,Q9NPH0 2 +Cholesterol biosynthesis with skeletal dysplasias 0.7945763314762138 1.9236791635180543 0.0543948113719618 0.9999999999999982 0.2341677340622756 6 Q16850,O75845,Q14739,Q15392 4 +Familial hyperlipidemia type 4 0.7550102798772684 1.9083570558297152 0.0563450832935232 0.9999999999999994 0.2379945401088063 3 Q9UBV2 1 +Progeriaassociated lipodystrophy 0.6690472959458825 1.8680224860833408 0.0617589367340467 1.0 0.2453682818590589 10 O75844,O60725,P46063 3 +Overlap between signal transduction pathways contributing to lmna laminopathies 0.5851753138201428 1.8638074070074684 0.0623487552098638 1.0 0.2457512624180996 16 O75844,O60725,P48729,P55209 4 +Arachidonate epoxygenase epoxide hydrolase 0.6697782963827348 1.8503349639857765 0.0642652862725783 1.0 0.2516711533384196 2 P34913 1 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.4976026756912279 1.8217921306577491 0.0684865322479513 1.0 0.2550388041380763 25 O76062,P37268,Q9UBM7,Q9BWD1,Q16850,O95864,O75845,Q15392,Q15800,Q14534,P35610,Q14739 12 +Exrna mechanism of action and biogenesis 0.6592765460910088 1.796362377023188 0.0724369033295952 1.0 0.2654603376231886 2 Q9HAV4 1 +Circadian rhythm genes 0.3870036659770713 1.7741996432664988 0.0760301332087844 1.0 0.2698847418580829 44 Q00839,P43490,P23246,P17844,Q03164,P54646,O14744,Q9UNS1,P78527,Q14103,Q9Y5V3,Q08211,P54802,P49327,Q9BWF3 15 +Mitochondrial immune response to sarscov2 0.6734730174518979 1.756551671429174 0.0789942567120947 1.0 0.2746154425553754 8 Q9Y6M9,Q9BQ95 2 +Preimplantation embryo 0.7148667435377558 1.7501497025409614 0.080092485243433 1.0 0.2762280599020674 7 Q92945,Q99729 2 +Metapathway biotransformation phase i and ii 0.4833242388636697 1.7070744785957142 0.0878082100507275 1.0 0.2912545546491347 25 Q7LGA3,O15217,P07099,Q06520,Q86UY6,Q16850,P21964 7 +Insulin signaling in adipocytes diabetic condition 0.7067069118625686 1.6823611499359583 0.0924988300519338 1.0 0.2970729621244647 3 P42345 1 +Insulin signaling in adipocytes normal condition 0.7067069118625686 1.6823611499359583 0.0924988300519338 1.0 0.2970729621244647 3 P42345 1 +Glycerophospholipid biosynthetic pathway 0.7738277662014434 1.6661314010883377 0.095687245432988 1.0 0.3025112394678319 4 P48651,O15228 2 +15q112 copy number variation syndrome 0.770044804634058 1.6497621803130396 0.0989915868362483 1.0 0.3081430421005268 4 Q06787 1 +Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.7654465791104823 1.6298422826928949 0.103134834764583 1.0 0.3145871593070448 4 P09601 1 +Acquired partial lipodystrophy barraquersimons syndrome 0.7458751226415173 1.619785172529681 0.1052784324900546 1.0 0.3160345663015216 5 O60725 1 +Sarscov2 and covid19 pathway 0.7598942894660059 1.6057568509328657 0.1083273446691612 1.0 0.3161283567989466 4 Q8WTV0,P35610 2 +Eicosanoid synthesis 0.6898124389033774 1.602446690865687 0.1090568669759872 1.0 0.3167345371025085 3 Q9NP80 1 +Nanomaterial induced apoptosis 0.6767792646877568 1.5632590017124273 0.1179916873171564 1.0 0.3331207172163441 7 P42574,Q9NR28,P49327,O95831 4 +Mitochondrial complex iii assembly 0.6072494103822196 1.527154989356006 0.1267224757804679 1.0 0.348056754745448 10 Q9UDW1,O14949,Q6DKK2 3 +Endothelin pathways 0.6058276338853472 1.5192260992848516 0.1287055939681698 1.0 0.3503331638505789 10 P00403,P42892 2 +Omega3 omega6 fatty acid synthesis 0.6969789309012997 1.475920317898607 0.1399652843901431 1.0 0.3742684036335545 6 O15254,Q15067 2 +Hostpathogen interaction of human coronaviruses autophagy 0.7074483556882531 1.4471659414464446 0.147850453005109 1.0 0.3919005457384331 5 Q14457 1 +Adipogenesis 0.5154539092213708 1.4058908374690664 0.1597565424942231 1.0 0.4091654906919554 16 O75844 1 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.7023413618303223 1.3544338271363854 0.1755980116149489 1.0 0.4351333945944468 4 Q15118 1 +Ketogenesis and ketolysis 0.6282780782573724 1.3226645377919832 0.1859469615724969 1.0 0.4514792226980225 7 P53985,P23786,P35610,O43772 4 +Caloric restriction and aging 0.6886515959562255 1.294368489030724 0.1955381695977034 1.0 0.4654575252776705 4 P43490 1 +Hostpathogen interaction of human coronaviruses apoptosis 0.6818711954742465 1.2646070382570775 0.2060122287881827 1.0 0.4846876855597942 4 P42574,Q07820 2 +Mrna processing 0.3053573243489846 1.2449634738379824 0.2131451769673749 1.0 0.4928473041858671 104 P55769,P61978,Q9BWJ5,P52756,P67809,Q14103,Q99729,P07910,Q15427,O43390,P55795,P62995,Q9UKA9,P23246,P31943,P26368,P22626,P62316,Q14562,Q6P2Q9,P38159,Q00839,P35637,Q08211,Q01081,Q9UHI6,O75400 27 +Apoptosis modulation by hsp70 0.6624859371848271 1.2438898635593758 0.2135401004956887 1.0 0.4928473041858671 5 P49327,O95831 2 +Disorders of folate metabolism and transport 0.5751316843301165 1.23587058159902 0.2165066737214513 1.0 0.4978013293519734 8 P00374 1 +Neuroinflammation 0.6631912401230696 1.1826366290420751 0.2369531891819738 1.0 0.5327058734572523 4 P00403 1 +Oxidative phosphorylation 0.3885814646972966 1.1775791381383025 0.2389644307941638 1.0 0.533277240779623 30 O75306,P51970,Q9Y6M9,O96000,Q86Y39,P03886,P24539,P06576,O75438,Q15904,O75964,O95168 12 +7oxoc and 7betahc pathways 0.5441048559907751 1.173075539589183 0.240765514509333 1.0 0.5333746982013327 10 P61916,O14975,Q9UBM7,O14734,O15118 5 +Ethanol effects on histone modifications 0.522754180543016 1.1700744639271767 0.2419710038462137 1.0 0.5340959975805517 12 O14929,P05091,P00374 3 +Tp53 network 0.5979926258421203 1.1636811714695552 0.2445532425304331 1.0 0.535481169127584 3 Q13315 1 +Extracellular vesiclemediated signaling in recipient cells 0.6437956204379249 1.1593393477373584 0.246317888973234 1.0 0.535481169127584 5 P04049,P35222,P42345,Q08431 4 +Triacylglyceride synthesis 0.6413693170669742 1.148374066212313 0.2508141749335311 1.0 0.5398730644845864 5 O15228 1 +Ebola virus infection in host 0.3296093889016229 1.1089151381468056 0.267466792659802 1.0 0.5656876067752606 44 P46934,P10321,P61586,O15118,P01889,P04439,P52294,O75569,Q08431 9 +Omega9 fatty acid synthesis 0.616238317757018 1.0991544121215628 0.2717007195676038 1.0 0.5706850751163612 6 O95573,O60488,O00767,O95864,P49327 5 +Intracellular trafficking proteins involved in cmt neuropathy 0.5086966317276658 1.0866416727391743 0.2771952005244418 1.0 0.5745861058909976 12 Q9NR77,Q15907 2 +Autophagy 0.5247387573414106 1.0644465840030797 0.2871264402391054 1.0 0.588803206841679 10 P54646,Q14457 2 +Cohesin complex cornelia de lange syndrome 0.4372221369580083 1.027441426262638 0.3042126532008355 1.0 0.607971482161175 18 Q14674,Q9Y6X3,Q96GD4,P30154,P53350,Q16537,Q14738 7 +Tryptophan metabolism 0.4670140871305765 1.015071025535219 0.3100719720693283 1.0 0.6106747171646515 15 P51648,P35610,Q15392 3 +Pregnane x receptor pathway 0.6105255112908405 1.0094517652053825 0.3127580232563058 1.0 0.6106747171646515 5 Q06520 1 +Aryl hydrocarbon receptor pathway wp2873 0.6050697866443967 0.9850118881858708 0.3246182315207995 1.0 0.6266361652096455 5 Q16543,Q07812,P07900 3 +Copper homeostasis 0.6031765790552981 0.9765434720965884 0.3287952160987704 1.0 0.6295857923405478 5 P42574,O75880,P05067 3 +Factors and pathways affecting insulinlike growth factor igf1akt signaling 0.5555228751794222 0.9614244629497788 0.3363387890574696 1.0 0.6360051244793896 7 Q15118,P42345 2 +T cell receptor and costimulatory signaling 0.5946413132661804 0.9384544199757632 0.3480109303625309 1.0 0.6451126451463002 5 Q15118 1 +Inclusion body myositis 0.5424350511751651 0.8999507832534638 0.3681464429742012 1.0 0.6534300419915439 3 P05067 1 +Nephrotic syndrome 0.458382648262057 0.8999254509824073 0.368159924812369 1.0 0.6534300419915439 14 O75844 1 +Pi3kaktmtor vitd3 signaling 0.5828453836796548 0.8860936734020682 0.3755670519388603 1.0 0.6627011643223495 5 P54646 1 +Vitamin b12 metabolism 0.5046340726919826 0.8625459807295843 0.3883871418482747 1.0 0.6773979717026655 8 Q8WTV0,Q99707 2 +Alzheimers disease and mirna effects 0.2817683873437999 0.8605681494545283 0.3894759343068044 1.0 0.6773979717026655 92 P42345,P12236,O95197,P28072,Q9NQC3,P21796,P33176,P05067,P49721,P45880,P16615,P48729,Q9Y277,P20618,P12235,P07437,Q96GC9,Q14457 18 +Sarscov2 b117 variant antagonises innate immune activation 0.4661610268378142 0.7887713321297463 0.4302456678278472 1.0 0.723173997349558 2 O94826 1 +Vitamin b12 disorders 0.5695102976272328 0.7778361112147374 0.4366656363734165 1.0 0.7261809350100378 4 Q99707 1 +Mecp2 and associated rett syndrome 0.372800830841828 0.737543372916322 0.4607919772222963 1.0 0.7559479193890105 23 P42345,P31943,P35637,Q03518,P52597 5 +Alzheimers disease 0.2692833792075051 0.6692634382922892 0.503327445167187 1.0 0.7984520966787848 90 P42345,P12236,O95197,P28072,Q9NQC3,P21796,P33176,P05067,P49721,P45880,P16615,P48729,Q9Y277,P20618,P12235,P07437,Q14457 17 +Ppar signaling pathway 0.37389184169239 0.6522678396651879 0.5142284029804269 1.0 0.8111667633124177 19 P23786,O14975,O95864,O15254,Q15067 5 +Dna damage response only atm dependent 0.3738324248915452 0.6518526745162323 0.5144962172574643 1.0 0.8111667633124177 19 Q15118,Q16537,P61586 3 +Constitutive androstane receptor pathway 0.4847236752460217 0.6228357206429909 0.5333924821534843 1.0 0.817599082492841 7 Q06520 1 +Regulation of apoptosis by parathyroid hormonerelated protein 0.5180377061095257 0.6077867202887798 0.5433289379960513 1.0 0.8245016634090079 5 Q9BXK5 1 +Spinal cord injury 0.3642000484575093 0.6029313447944425 0.5465543628732381 1.0 0.827327925845525 20 P08670,P61586,P04083 3 +Nanoparticle triggered autophagic cell death 0.5034436347897893 0.5907013253124067 0.5547205598057838 1.0 0.8313959995113847 6 Q96GC9 1 +Ptf1a related regulatory pathway 0.4241540256709493 0.5830569508500428 0.5598549624311582 1.0 0.8322588643414945 2 P35222 1 +Inflammatory response pathway 0.4238623103850701 0.5816823169901822 0.5607806845398209 1.0 0.8322588643414945 2 P11047 1 +Microglia pathogen phagocytosis pathway 0.5091970802919746 0.5716138781732567 0.5675835912308913 1.0 0.8362214560125024 5 P63000,O00459,O00443,P16885 4 +Disruption of postsynaptic signaling by cnv 0.4339526506502067 0.5389181708237435 0.5899433185991549 1.0 0.8550034527219579 9 Q14168,Q06787 2 +Envelope proteins and their potential roles in edmd physiopathology 0.366162458343727 0.5385580504172061 0.5901918396878094 1.0 0.8550034527219579 18 O94901,P33176,P61586,Q14739 4 +Kennedy pathway from sphingolipids 0.5055797191688784 0.5198639507523798 0.6031584027362442 1.0 0.8655251783945632 4 P48651,O95470 2 +Cholesterol biosynthesis pathway 0.3971386777577794 0.4937396800669629 0.6214900379635921 1.0 0.8785245030967412 13 Q15800,Q14534,P37268 3 +Nanoparticle triggered regulated necrosis 0.399358226371067 0.4697087048352334 0.6385631478292089 1.0 0.8869744410350796 2 Q13546 1 +Pi3kakt signaling pathway 0.273775590299822 0.4596052043071189 0.6457996229085801 1.0 0.8919974152108536 46 P42345,Q16543,P62753,P54646,P14625,P30154,Q07820,Q14738,P23588,Q16537,P07900 11 +Vitamin a and carotenoid metabolism 0.4805018679966765 0.4585074488671881 0.646587912179202 1.0 0.8919974152108536 5 Q8WTV0 1 +Fluoroacetic acid toxicity 0.4791421890317522 0.4533334303418951 0.6503086638293629 1.0 0.8942956389289226 5 P51648 1 +Hippo signaling regulation pathways 0.3517213870697662 0.4462813768729637 0.6553940068821187 1.0 0.8948627321649245 18 P54646,P61586 2 +Folate metabolism 0.3814539503553359 0.4453925361993585 0.6560361051291457 1.0 0.8948627321649245 14 Q8WTV0,P00374 2 +Oxysterols derived from cholesterol 0.4195119766519389 0.4432061942036663 0.6576165989613401 1.0 0.8950073443263081 8 Q9Y305,Q9UBM7,O14975,O14734 4 +Synaptic signaling pathways associated with autism spectrum disorder 0.4074515791181012 0.4409775832123717 0.6592292257244377 1.0 0.8951949441045496 10 P54646 1 +Vitamin d receptor pathway 0.3817415244925932 0.4120759940053011 0.6802837234914727 1.0 0.909542335152696 13 Q06520,P08183,Q96KA5 3 +Purinergic signaling 0.4236941931718793 0.3859013525613198 0.6995697288731746 1.0 0.9192224040053836 3 P63096,P04899 2 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.3786464410735209 0.381435702303732 0.7028799732198152 1.0 0.9192224040053836 2 Q9P2K5 1 +Leptininsulin signaling overlap 0.3786464410735114 0.3814357023036931 0.7028799732198441 1.0 0.9192224040053836 2 O14654 1 +Erk pathway in huntingtons disease 0.4570220444435133 0.3719106100355346 0.709959405216555 1.0 0.9192224040053836 5 P42574,P42858 2 +Angiopoietinlike protein 8 regulatory pathway 0.297067088154866 0.3627411276316075 0.7167982738259024 1.0 0.9192224040053836 30 P42345,Q15418,P11166,P54646,O75955,Q9UPT5,O00767,P46108,P51812,P49327 10 +Tyrobp causal network in microglia 0.441867706905193 0.3472913630970748 0.7283724387290293 1.0 0.9192280226547532 6 Q15758,Q15418,A0AV96,P61916 4 +Thermogenesis 0.3055554368475918 0.3380904126197919 0.7352950552170192 1.0 0.922433034443034 27 P23786,Q15418,P54646,P42345 4 +Wnt signaling pathway 0.3645404634772465 0.3257720739260009 0.7445968088866999 1.0 0.9240713681028891 13 P42345,P61586,P48729 3 +Rett syndrome causing genes 0.3379531319722446 0.3200879455569165 0.7489016633901215 1.0 0.9240713681028891 17 P51532,P42858,Q9Y4A5,Q8WXH0,P27695,P49770,Q13547,P46108,P28370 9 +P53 transcriptional gene network 0.3859475831094017 0.3193697184921631 0.7494461705709801 1.0 0.9240713681028891 9 P11166,Q709F0,P49327,P04066 4 +Hematopoietic stem cell gene regulation by gabp alphabeta complex 0.4338830064979738 0.3189103451451309 0.7497944993256538 1.0 0.9240713681028891 6 Q13315 1 +Amyotrophic lateral sclerosis als 0.3715817097607606 0.2800544885273444 0.7794357009234452 1.0 0.9368662781396658 10 Q9BUN8 1 +Mitochondrial long chain fatty acid betaoxidation 0.3521946602146568 0.2676155416840616 0.7889952666592162 1.0 0.9409039820474346 13 P40939,P23786,O95573,P50416,P42126,O43772,Q16836 7 +Nipbl role in dna damage cornelia de lange syndrome 0.4154247994306851 0.2568006035508311 0.7973327041281113 1.0 0.94898225765836 6 Q13535 1 +Joubert syndrome 0.2965990723514546 0.2339253411823387 0.8150429395268373 1.0 0.9606358847376648 25 P42345,Q10713,P61586,Q13315,P41208 5 +Mammary gland development pathway involution stage 4 of 4 0.3787569302597081 0.2318949179564877 0.8166196318363015 1.0 0.9606358847376648 3 P04637,Q07812 2 +Orexin receptor pathway 0.3120298322225564 0.2169481826256648 0.8282487273888741 1.0 0.9615338300388366 18 P11177,P11166,Q15118,Q13595,O60313 5 +Interactome of polycomb repressive complex 2 prc2 0.4024863730699634 0.216426290696534 0.8286554748447854 1.0 0.9615338300388366 6 Q9Y2W1,Q15022,Q14149 3 +Onecarbon metabolism 0.3343424355587536 0.2109846052132187 0.8328992842266287 1.0 0.9615338300388366 14 P00374 1 +Hair follicle development organogenesis part 2 of 3 0.4127262113251653 0.2107095928304503 0.833113888666634 1.0 0.9615338300388366 4 P35222,P05556,Q9BZE4 3 +Glycogen synthesis and degradation 0.3100805378014897 0.2068488593677306 0.8361278969618327 1.0 0.9615338300388366 18 P46976,P52789,Q04446,P30154,Q16537,Q14738 6 +Target of rapamycin tor signaling 0.3530744811103501 0.2068449218748047 0.8361309721313792 1.0 0.9615338300388366 10 P54646 1 +Methionine de novo and salvage pathway 0.3566186892405806 0.204841644974598 0.8376958488524799 1.0 0.9615338300388366 9 Q13126 1 +Development of ureteric collection system 0.4026277372262822 0.1985681854114091 0.8426005423571725 1.0 0.9615338300388366 5 Q13418,P35222,P05556,O94813 4 +Fluoropyrimidine activity 0.3344120740613731 0.1903122316283464 0.849064469358841 1.0 0.9615338300388366 13 P31350,P00374,Q06203,Q92820 4 +Riboflavin and coq disorders 0.3903429450542155 0.1810939493586805 0.8562938337908927 1.0 0.9625376983538368 6 Q5T2R2,Q16134,Q86YH6 3 +Pdgf pathway 0.3156775755497733 0.1525927709368872 0.8787194261912143 1.0 0.9715409492325524 15 P00403 1 +Type ii interferon signaling ifng 0.3622704909091159 0.1515392931156826 0.8795503172948145 1.0 0.9715409492325524 7 Q03518 1 +Bdnftrkb signaling 0.3372509860296845 0.1311172827280776 0.8956825295515691 1.0 0.9752728836527772 8 P42345 1 +Fatty acid betaoxidation 0.2883194114299591 0.1300282190741999 0.896544100623146 1.0 0.9752728836527772 19 O43772,P23786,P35610,P43304 4 +Ncrnas involved in wnt signaling in hepatocellular carcinoma 0.3253234823987116 0.112317661456468 0.910571538593083 1.0 0.986821022445921 10 Q86UE4 1 +Head and neck squamous cell carcinoma 0.3096918184950589 0.111104649834996 0.9115333615385262 1.0 0.986821022445921 14 P54646 1 +Vasopressinregulated water reabsorption 0.2994492959544632 0.106370130093646 0.9152886913295776 1.0 0.986821022445921 16 Q9UJW0 1 +Corticotropinreleasing hormone signaling pathway 0.2719116453649465 0.0880397167748767 0.9298451092614166 1.0 0.992291577606354 25 Q06520,P54646,P42892 3 +Camkk2 pathway 0.3053287637956055 0.0829070996554564 0.9339254087704104 1.0 0.9931546291938342 13 P42345,P09601 2 +Chromosomal and microsatellite instability in colorectal cancer 0.2870880988302228 0.0767523175115281 0.9388205838965336 1.0 0.994527215401738 17 P42574,P04049,Q96KP1,P11233,P52701,P48729,P61586 7 +Genes controlling nephrogenesis 0.3158971361776745 0.0741114883189585 0.9409216740450494 1.0 0.9946631603693528 8 Q12948,O94813,Q9Y5K6,Q13418,P35222,P11047,P05556 7 +Vitamin dsensitive calcium signaling in depression 0.329814597333602 0.0707873394957789 0.9435670081655334 1.0 0.9946631603693528 7 Q8NB78 1 +G1 to s cell cycle control 0.2714998342764128 0.0692768713627874 0.9447692354772654 1.0 0.9946631603693528 23 Q13315,Q14566,Q9Y619 3 +Rala downstream regulated genes 0.3455365642788983 0.0683543862523785 0.9455035313560404 1.0 0.9946631603693528 5 Q96KP1 1 +Proximal tubule transport 0.2952010384700592 0.0304425220400031 0.9757141328733224 1.0 1.0 9 P08183,P05023 2 +Arrhythmogenic right ventricular cardiomyopathy 0.2739038014246323 0.0287928711363136 0.9770297865334824 1.0 1.0 17 P50402,Q99959,P16615 3 +Smc1smc3 role in dna damage cornelia de lange syndrome 0.2937737503653836 0.0275407234000458 0.978028459578442 1.0 1.0 9 Q92878,O60216,Q14683,Q13315,P49959,P38398,Q9UQE7,Q14676 8 +Ectoderm differentiation 0.2680190121160338 0.0233411282861144 0.9813781650124244 1.0 1.0 18 P16278 1 +Focal adhesion pi3kaktmtorsignaling pathway 0.227760735241438 0.0191771200028159 0.9846998098394182 1.0 1.0 46 P42345,Q16543,P54646,P14625,Q15907,Q14738 6 +Heme biosynthesis 0.3097767653570934 0.0162043637619349 0.9870713541428602 1.0 1.0 5 P22830 1 +Atr signaling 0.3091036654047093 0.0154287193440884 0.9876901514280936 1.0 1.0 5 Q13535 1 +Mirna regulation of p53 pathway in prostate cancer 0.3012227412517924 0.0068761329577827 0.9945136829082716 1.0 1.0 5 P42574,Q13315 2 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8177a43872b40f9afb2bff75a03561dbc74608c2 --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Activation of nlrp3 inflammasome by sarscov2", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoe and mir146 in inflammation and atherosclerosis", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes associated with the development of rheumatoid arthritis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Genes targeted by mirnas in adipocytes", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Hypothetical craniofacial development pathway", "Id signaling pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Ldlrad4 and what we know about it", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoblast signaling", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 altering angiogenesis via nrp1", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Srf and mirs in smooth muscle differentiation and proliferation", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Tamoxifen metabolism", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAR2", "AARS", "AASS", "ABAT", "ABCB1", "ABCD3", "ABCF1", "ABCF2", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ACY1", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT4", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP8", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "AMOT", "ANAPC1", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APBB1", "APEX1", "APIP", "APMAP", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARG2", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL8B", "ARMC8", "ARMC9", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG7", "ATG9A", "ATIC", "ATM", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AURKA", "AURKB", "B3GALT6", "BAG2", "BAG3", "BAG4", "BAIAP2", "BANF1", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BCAS3", "BCAT1", "BCAT2", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BECN1", "BLM", "BLVRA", "BPTF", "BRCA1", "BRD4", "BRIX1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "C1QBP", "C21orf59", "CAB39", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPZB", "CARM1", "CASK", "CASP3", "CASP7", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR2", "CCDC124", "CCDC6", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC6", "CDC73", "CDCA7L", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK9", "CDKAL1", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CEP170", "CEP250", "CEP290", "CEP44", "CEP97", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK1", "CHEK2", "CHMP5", "CHORDC1", "CHRAC1", "CHTF18", "CHTF8", "CHUK", "CIP2A", "CISD1", "CIT", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLIP1", "CLK3", "CLPTM1L", "CLTA", "CLTB", "CLTC", "CLUH", "CMPK1", "CNN2", "CNOT1", "CNOT10", "CNP", "COA3", "COASY", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CREBBP", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCP1A", "DCTD", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERA", "DERL1", "DFFA", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIP2A", "DLAT", "DLD", "DLST", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNMT1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC2", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHD1", "EHHADH", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELP3", "EMD", "EML4", "ENAH", "ENDOG", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ESD", "ESPL1", "ESS2", "ETF1", "ETFA", "ETFDH", "ETHE1", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC2", "EXOSC4", "EXOSC7", "EXOSC9", "EXTL3", "EZR", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FAM91A1", "FANCA", "FANCD2", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FKBP10", "FKBP15", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GALNT1", "GAMT", "GAPDH", "GART", "GBA", "GBE1", "GCC2", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GID8", "GIGYF2", "GLA", "GLB1", "GLS", "GLUD1", "GM2A", "GMPPB", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNB1L", "GNG5", "GNPAT", "GNS", "GOT1", "GOT2", "GPD1L", "GPD2", "GPHN", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSK3A", "GSR", "GSS", "GSTA4", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F2", "GTF2H1", "GTF2I", "GTPBP4", "GTSE1", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HGS", "HIBADH", "HIBCH", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HTT", "HUS1", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF2", "ILK", "IMP3", "IMPDH2", "INF2", "INPP4A", "INPPL1", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BPL", "IRS4", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KATNB1", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIDINS220", "KIF1B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC2", "KLC4", "KMT2A", "KNSTRN", "KPNA1", "KPNA4", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRPPRC", "LRRC59", "LRRC8A", "LRRFIP1", "LRWD1", "LSM2", "LSM7", "LSS", "LTA4H", "LUC7L", "LZTFL1", "MACF1", "MAGED1", "MAGT1", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC2", "MARCKS", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD1", "MBD3", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCRS1", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MEPCE", "MFAP1", "MFGE8", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MMACHC", "MOCS1", "MOCS2", "MOGS", "MORC3", "MORF4L1", "MOV10", "MPC2", "MPI", "MPP1", "MPP2", "MPST", "MRE11", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFR", "MTMR2", "MTMR6", "MTOR", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAA40", "NAA50", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAM1", "NCAPG", "NCAPG2", "NCBP1", "NCBP2", "NCDN", "NCKAP1", "NCL", "NCOR1", "NCSTN", "ND1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NET1", "NEU1", "NF1", "NFATC2IP", "NIPBL", "NKRF", "NME1", "NME3", "NME7", "NONO", "NOP2", "NOTCH2", "NPAT", "NPC1", "NPC2", "NRP1", "NSDHL", "NSF", "NT5C3A", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "ORC3", "OTUD7B", "OXCT1", "OXSM", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAIP1", "PAK2", "PAK4", "PAPOLA", "PAPSS1", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PCNT", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PEBP1", "PELO", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF6", "PHGDH", "PHLDB2", "PI4K2A", "PI4KA", "PIBF1", "PIGT", "PIK3C2A", "PIK3R2", "PIK3R4", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLCG1", "PLCG2", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PMVK", "PNKP", "PNP", "PNPLA8", "PNPO", "PNPT1", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "PON2", "POR", "POU2F1", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF18", "PRPF3", "PRPF38A", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTBP2", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QKI", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB21", "RAB23", "RAB2A", "RAB3B", "RAB4A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RABGAP1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAF1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RASAL2", "RB1", "RBBP4", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM47", "RBM5", "RBMX", "RCC1", "RCN1", "RDX", "RECQL", "REL", "RELA", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RGS10", "RHBDD2", "RHEB", "RHOA", "RHOG", "RIF1", "RIPK1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RNF20", "RNF40", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRBP1", "RRM1", "RRM2", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAR1A", "SAR1B", "SARS", "SATB2", "SC5D", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEL1L", "SELENBP1", "SEPT11", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETD7", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SFMBT1", "SFPQ", "SFSWAP", "SGK3", "SGPL1", "SH3GL1", "SH3GLB1", "SH3RF1", "SHMT1", "SHMT2", "SIN3A", "SIPA1", "SIRT1", "SIRT2", "SKP1", "SKP2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SMYD3", "SMYD4", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPNS1", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SRCAP", "SREK1", "SRM", "SRP54", "SRPK1", "SRPK2", "SRRM1", "SRSF1", "SRSF10", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSNA1", "SSR3", "SSR4", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STRAP", "STRN", "STUB1", "STX3", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TAF6", "TALDO1", "TAOK1", "TAP1", "TARDBP", "TBC1D4", "TBCA", "TBL2", "TCF20", "TCP1", "TDP2", "TECR", "TELO2", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFB2M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM7SF2", "TMED10", "TMEM43", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOPBP1", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM33", "TRIO", "TRIP13", "TRMT2A", "TRRAP", "TSG101", "TSPO", "TSPYL1", "TTC19", "TTC26", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TXNDC5", "TXNL4A", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2L3", "UBE2N", "UBE2T", "UBE3A", "UBR2", "UBR5", "UBTF", "UBXN7", "UCHL5", "UCK2", "UFD1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNG", "UPF1", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP32", "USP5", "USP7", "USP8", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VASP", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS16", "VPS18", "VPS28", "VPS33A", "VPS37B", "VPS4A", "WAPL", "WARS", "WASF2", "WDCP", "WDHD1", "WDR1", "WDR35", "WDR48", "WDR5", "WDR74", "WFS1", "WIPI2", "WNK1", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YPEL5", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZMYM3", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["ABCB1", "ACAD11", "ACAT2", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSL3", "ACSL4", "AIFM1", "ALDH2", "ALDH3A2", "ANXA1", "APEX1", "APP", "ASAH1", "ATM", "ATP1A1", "ATP2A2", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6AP1", "ATR", "AURKB", "BAX", "BCL2L13", "BECN1", "BRCA1", "CASP3", "CD2AP", "CDC37", "CERS2", "CETN2", "CLPTM1L", "COA3", "COMT", "COX15", "COX2", "COX4I1", "COX6B1", "COX7A2", "CPT1A", "CPT2", "CRK", "CRTAP", "CSNK1A1", "CTNNB1", "CYB5B", "CYC1", "CYP51A1", "DCTN4", "DDX20", "DDX5", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHX8", "DHX9", "DIABLO", "ECE1", "ECI1", "ECSIT", "EIF2B2", "EIF4B", "EMD", "EPHX1", "EPHX2", "ESPL1", "ETFDH", "EXOC2", "EXOC7", "FADS2", "FASN", "FDFT1", "FECH", "FKBP10", "FLOT1", "FMR1", "FOXC1", "FOXRED1", "FUCA1", "FUS", "GBA", "GBE1", "GGH", "GLA", "GLB1", "GM2A", "GNAI1", "GNAI2", "GNPAT", "GNS", "GPD2", "GSTA4", "GTPBP4", "GYG1", "HADH", "HADHA", "HAT1", "HDAC1", "HEXA", "HK2", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPR", "HNRNPU", "HS2ST1", "HSP90AA1", "HSP90B1", "HTT", "ICMT", "IDH1", "ILK", "IRS4", "ITGB1", "KDM1B", "KDSR", "KHSRP", "KIF5B", "KMT2A", "KPNA1", "LAMC1", "LBR", "MAGED1", "MAU2", "MCL1", "MCM6", "MDC1", "MFGE8", "MORC3", "MPP2", "MRE11", "MSH6", "MSMO1", "MTAP", "MTDH", "MTOR", "MTR", "MYEF2", "NAA40", "NAGLU", "NAMPT", "NAP1L1", "ND1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEDD4", "NEU1", "NPC1", "NPC2", "OPA1", "P3H1", "P4HA1", "PDHB", "PDK1", "PDSS1", "PDSS2", "PIK3C2A", "PIK3R2", "PKP2", "PLCG2", "PLK1", "PMPCA", "PNPLA8", "POR", "PPAT", "PPP2R1B", "PPP2R5D", "PPP2R5E", "PRKAA2", "PRKDC", "PRKRA", "PRMT5", "PRPF40A", "PRPF8", "PSMB1", "PSMB2", "PSMB6", "PTBP2", "PTDSS1", "PXMP2", "RAB11B", "RAC1", "RAD21", "RAD50", "RAF1", "RALA", "RBM4", "RBM47", "RBM5", "RBMX", "RECQL", "RHOA", "RIPK1", "RPS6", "RPS6KA1", "RPS6KA3", "RRM2", "RTN3", "RTN4", "SC5D", "SCARB1", "SCD", "SCO1", "SDHB", "SEL1L", "SF3B4", "SF3B5", "SFPQ", "SGPL1", "SLC16A1", "SLC1A5", "SLC25A15", "SLC25A20", "SLC25A4", "SLC25A6", "SLC27A2", "SLC2A1", "SLC35B2", "SLC39A14", "SLIT2", "SMARCA1", "SMARCA4", "SMC1A", "SMC3", "SNRPD2", "SNU13", "SOAT1", "SPTLC1", "SPTLC2", "SQLE", "SULT2A1", "SUN1", "SUZ12", "SYNE2", "TAP1", "THRAP3", "TIMELESS", "TIMMDC1", "TM7SF2", "TOMM70", "TP53", "TRA2A", "TRA2B", "TRRAP", "TTC19", "TUBB", "U2AF1", "U2AF2", "UQCR10", "UQCRQ", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "XPO5", "YBX1", "ZMPSTE24"]} \ No newline at end of file diff --git a/opencell_localization/advanced/idx2term.json b/opencell_localization/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..15f802caf6af65652341957c3b7286520a1d9511 --- /dev/null +++ b/opencell_localization/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "er"} \ No newline at end of file diff --git a/opencell_localization/advanced/plot_0.png b/opencell_localization/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..cb66a373c14688dfde17204b39b3fc4364990ab7 --- /dev/null +++ b/opencell_localization/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:437ba91bbcc99fe5fdcf7d4637333fcfe0fe819876ced411dbca0f703a3e4f88 +size 196041 diff --git a/opencell_localization/basic/idx2term.json b/opencell_localization/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6accb8ec14605df7026ac64b2cd2a8243f695340 --- /dev/null +++ b/opencell_localization/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "er", "1": "nuclear_membrane", "2": "vesicles", "3": "nucleolus_fc_dfc"} \ No newline at end of file diff --git a/opencell_localization/basic/plot_0.png b/opencell_localization/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..394edc5378dd5e7671fb3fb835247d763212c9b4 --- /dev/null +++ b/opencell_localization/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e8aa8ab4c89038ce9b40c29625658cdef72c6a4d2593b10115cdc600da9a4177 +size 138026 diff --git a/opencell_localization/basic/plot_1.png b/opencell_localization/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..2ea59f65b994d4a4fb733dfe55bc76684b4e3d4d --- /dev/null +++ b/opencell_localization/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8632432c488ee50a2920c2059ecc015d7922f75ab0ad089ab1995b65e8f0098f +size 143479 diff --git a/opencell_localization/basic/plot_2.png b/opencell_localization/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..d488351b9d283d3a076273a37d2e780883caae0d --- /dev/null +++ b/opencell_localization/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:57630dcc6aa90de3b9b76224798642480486f154998c2d8cb91c74454ff2fc7b +size 138346 diff --git a/opencell_localization/basic/plot_3.png b/opencell_localization/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..c5364d5a0c7750ab289720d0a5837a628e7b9e41 --- /dev/null +++ b/opencell_localization/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3e771442752e085178895664b3cd184da0b8a062f14b907092d5050f644d9fe1 +size 146405 diff --git a/opencell_localization/consensus.joblib b/opencell_localization/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..0ed4277680d2823fd9fcd14dde63c8e2fe7137ad --- /dev/null +++ b/opencell_localization/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:143c563a6f14f2120578d48a5d59acb75531efbcc48ea29d1d1f4250bd43ab70 +size 80592 diff --git a/opencell_localization/df_merge.tsv b/opencell_localization/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..56bd283b15d25c92911ae7eba9f69a8d05d03cad --- /dev/null +++ b/opencell_localization/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +er 35 88 2.789379045279212 0.0052809218228317 29.17233009708738 87.61893203883496 1.3358083950399515 0.3757472714196316 13.465054065187209 8.223393744963309 2.0429537263872786 0.4010648005920765 9.691384873288812e-06 0.50487672715324 0.1629635375300463 4.262122359695514e-05 3.852921392107203e-09 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..5ecf7c9f9e80a7b07d46f95686832594b6e5c0fe --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 103.11764705882354 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..fdd47a877e7aa9c02638dcd88b13ccc928f0bc7e --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..db1c02aafd96060a88cedcd0920195fdcc97d99f --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +er 0.4081233773790556 2.789379045279212 0.0052809218228317 0.0860812057387008 0.0299252236627135 88 Q06136,Q9P2W9,O96005,O00767,O00264,Q9UM00,Q15392,Q13190,O15269,O15270,Q9Y487,P46977,Q8NHH9,Q96N66,Q96GC9,Q9NPA0,P51572,Q969Q5,Q9BZF1,Q15041,Q16850,O75845,O95470,Q14739,O15173,Q9NQC3,P48651,Q5HYI8,Q9Y5M8,Q8NF37,P04844,Q8TCJ2,Q8TBX8,Q96A33,Q07065 35 +mitochondria 0.6679051790991679 1.8617998038566077 0.0626313141745062 0.6669744914938633 0.2129464681933214 10 P21796,Q9Y277,P45880 3 +nuclear_membrane 0.3836771048425419 1.2250618800600557 0.2205519064543384 0.9855328699521102 0.4211666591511049 33 P42167,O75694,O60684,Q9UBU9,P52292,O00629,Q92973,Q9C0E2,Q96QU8,P52294,P49792,P42166,P52948,P35658,Q14739 15 +vesicles 0.2714279871481441 0.9520454006055936 0.3410739573437193 0.9991678082007676 0.5798257274843229 179 Q06136,P20020,P11279,P51798,O96005,O00767,O00264,P53985,Q9Y5X2,Q9UM00,P30825,Q15907,Q15392,Q8IZ07,Q14457,O15269,Q10713,P11166,Q13277,Q9H2V7,O95249,P49257,P22059,Q5VW38,O43808,Q9BZF1,O15127,Q96L92,Q9BTU6,P61586,Q8IY95,Q8NBN3,O75845,O95470,Q93050,Q8IZA0,P42345,O15173,P05023,O60476,Q15904,Q5HYI8,P13473,P04439,Q8NF37 45 +nucleolus_fc_dfc 0.3440300013030672 0.5462841506409555 0.584870629250805 0.9999996770622316 0.710200049804549 24 P55769,P78332,O95429,Q96PK6,Q9NY12,Q01844 6 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..6a0346ef06d8f8102277601b923c4dd859d4e3cb --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AATF", "ABCE1", "ACAP2", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AGAP3", "AHCY", "AHSA1", "AKAP12", "AKAP13", "AKAP8L", "AKR1A1", "AKT1S1", "ALDH16A1", "ALDH9A1", "ALG2", "ANAPC16", "ANAPC4", "ANKRD13A", "ANKRD17", "ANXA11", "AP2B1", "AP2S1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARHGAP1", "ARHGAP17", "ARHGEF7", "ARID1A", "ARL1", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARPC2", "ARPC3", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATL2", "ATL3", "ATM", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATXN10", "ATXN2L", "AURKB", "BAG4", "BAG6", "BAIAP2", "BANF1", "BAZ1A", "BAZ1B", "BCAP31", "BECN1", "BLM", "BLVRA", "BMS1", "BOP1", "BPNT1", "BRD2", "BRD4", "BTF3", "BUB1", "BUB1B", "BUD23", "BYSL", "C1orf123", "C21orf59", "CAD", "CALD1", "CALM3", "CAMK1", "CAMK2G", "CANX", "CAPRIN1", "CAPZB", "CASP3", "CASP7", "CBX1", "CCAR1", "CCDC22", "CCDC47", "CCDC86", "CCDC93", "CCNB1", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC16", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CEP170", "CEP250", "CETN2", "CHEK1", "CHEK2", "CHM", "CHMP7", "CHUK", "CKAP2", "CKAP4", "CKAP5", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLINT1", "CLIP1", "CLK3", "CLNS1A", "CLPTM1", "CLTA", "CLTB", "CLTC", "CNN2", "COIL", "COMMD2", "COPA", "COPB2", "COPE", "COPG1", "COPG2", "COPZ1", "CORO1B", "CORO1C", "CPSF6", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CTBP1", "CTBP2", "CTNNB1", "CTNNBL1", "CTPS1", "CTTN", "CUTC", "CYB5R3", "CYP51A1", "DAD1", "DBNL", "DCP1A", "DCP1B", "DCTN2", "DDB1", "DDOST", "DDX21", "DDX39B", "DDX47", "DDX5", "DDX56", "DDX6", "DHCR24", "DHX37", "DHX9", "DIAPH1", "DKC1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB6", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DOCK7", "DPH2", "DRG1", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNLL1", "EBNA1BP2", "ECT2", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1G", "EFTUD2", "EIF2AK2", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3K", "EIF3M", "EIF4A1", "EIF4A3", "EIF5", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMG1", "ENO1", "ENY2", "EPN1", "EPS15", "ESD", "ESYT1", "EWSR1", "EZR", "FAM120A", "FAM50A", "FANCA", "FASN", "FAU", "FBL", "FDPS", "FKBP5", "FKBP8", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAK", "GAPDH", "GAR1", "GBF1", "GDI1", "GDI2", "GET4", "GNB1", "GNL2", "GNL3", "GOLGA2", "GOLT1B", "GORASP2", "GOSR1", "GPR107", "GRB2", "GSK3A", "GSPT1", "GTF2F1", "GTPBP4", "GYG1", "GYS1", "H1F0", "HDAC1", "HDAC2", "HEATR3", "HGS", "HIP1", "HLA-A", "HMGA1", "HMGB2", "HMGCS1", "HNRNPA0", "HNRNPC", "HNRNPD", "HNRNPH1", "HNRNPL", "HNRNPU", "HSP90AA1", "HSP90AB1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPBP1", "HSPH1", "HUS1", "IDI1", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF3", "ILK", "IMP3", "INPP4A", "INPPL1", "INTS14", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IRAK1", "IST1", "ITSN2", "KDSR", "KIAA0319L", "KIAA0368", "KIF11", "KIF1B", "KIF20A", "KIF22", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KLC1", "KLC2", "KLC4", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "LAMP1", "LAMP2", "LAMTOR2", "LARP7", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LIG1", "LMAN1", "LMNA", "LMNB1", "LNPK", "LPCAT1", "LSM14B", "LSS", "LTV1", "MAN1A2", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MAPRE1", "MARK2", "MBOAT7", "MCM10", "MDH1", "MECP2", "MED14", "MED17", "MED21", "MED24", "MED4", "METAP2", "MFN1", "MIF", "MKI67", "MPHOSPH10", "MRTO4", "MSH6", "MSN", "MTMR2", "MTOR", "MVD", "MYBBP1A", "MYH10", "MYH9", "MYL6", "MYO1B", "MYO1C", "MYO1E", "MYO6", "NAF1", "NANS", "NAPA", "NAPG", "NCAPH", "NCKAP1", "NCL", "NCLN", "NDRG1", "NECAP1", "NECAP2", "NEK9", "NEMF", "NET1", "NHP2", "NIFK", "NMD3", "NOL10", "NOL11", "NOM1", "NONO", "NOP2", "NOP53", "NOP58", "NPM1", "NRBP1", "NSA2", "NSDHL", "NUCKS1", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP214", "NUP98", "NUTF2", "NVL", "NXF1", "OCRL", "OSBP", "OSBPL11", "OSBPL8", "PABPC4", "PACSIN2", "PACSIN3", "PAIP1", "PAK2", "PAK4", "PARP1", "PBK", "PCNA", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PES1", "PFDN6", "PFN1", "PGK1", "PGRMC1", "PGRMC2", "PHAX", "PHGDH", "PI4K2A", "PI4KA", "PICALM", "PIK3C2A", "PIK3R2", "PIN4", "PIP4K2C", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PMPCA", "PMVK", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "PPM1G", "PRKACA", "PRKCA", "PRKCD", "PRKDC", "PRMT9", "PRPF19", "PRPF4B", "PRPF8", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTDSS1", "PTDSS2", "PTGES3", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB3GAP2", "RAB4A", "RAB5B", "RAB7A", "RABEP1", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACK1", "RAD21", "RAF1", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGRF", "RBBP4", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "REEP5", "RELA", "RER1", "RHEB", "RHOA", "RHOG", "RIOK1", "RIOK2", "RNASEH2A", "RNF40", "ROCK1", "RPL10A", "RPL11", "RPL13", "RPL19", "RPL27", "RPL35", "RPL4", "RPL5", "RPN1", "RPN2", "RPP30", "RPS11", "RPS14", "RPS16", "RPS18", "RPS6KA1", "RPS6KA3", "RRP1", "RRP36", "RSL1D1", "RTCB", "RTN4", "RUVBL1", "RUVBL2", "S100A10", "SACM1L", "SAE1", "SAR1A", "SAR1B", "SARS", "SBDS", "SC5D", "SCAMP2", "SCD", "SCFD1", "SCYL1", "SCYL2", "SEC16A", "SEC22B", "SEC23A", "SEC24C", "SEC24D", "SEC31A", "SEC61B", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFPQ", "SGPL1", "SH3GL1", "SH3GLB1", "SH3GLB2", "SLC16A1", "SLC1A5", "SLC25A17", "SLC27A4", "SLC2A1", "SLC35F2", "SLC7A1", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMN1*", "SNRNP40", "SNRPA", "SNRPB2", "SNRPC", "SNRPD2", "SNU13", "SNX1", "SNX12", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX8", "SNX9", "SPNS1", "SPTLC1", "SPTLC2", "SRI", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK2", "SRPRA", "SRPRB", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STIP1", "STK4", "STT3A", "STT3B", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "SUPT16H", "SUPT5H", "SYAP1", "TAOK1", "TARDBP", "TCOF1", "TERF2", "TFRC", "TGFBRAP1", "TIA1", "TJP1", "TJP2", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM192", "TMEM87A", "TMPO", "TMPO", "TNPO1", "TNPO3", "TOMM20", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TPR", "TPT1", "TRAPPC11", "TRIM28", "TRIM33", "TRIR", "TRMT1L", "TRRAP", "TSG101", "TSR1", "TTK", "TUBB4B", "TWISTNB", "U2AF2", "U2SURP", "UBA1", "UBA5", "UBE2M", "UBTF", "UFC1", "UGDH", "ULK3", "UPF1", "USP10", "USP32", "USP7", "UTP14A", "UTP4", "UTP6", "UTRN", "VAPA", "VAPB", "VASP", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS16", "VPS18", "VPS25", "VPS28", "VPS29", "VPS33A", "VPS35", "VPS37B", "VPS4A", "VRK2", "VRK3", "WAPL", "WASF2", "WBP2", "WDR12", "WDR3", "WDR46", "WDR75", "WNK1", "XPO1", "XPO4", "XPO5", "XPO6", "XPOT", "YES1", "YKT6", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZNF326", "ZNF598", "ZYX"], "leading_proteins": ["ANKRD13A", "ARL6IP1", "ATL2", "ATP1A1", "ATP2B1", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "BAG4", "BCAP31", "BECN1", "CCDC47", "CKAP4", "CLCN7", "CLPTM1", "CYP51A1", "DHCR24", "EMC7", "EWSR1", "GAR1", "GOSR1", "GPR107", "HLA-A", "KDSR", "KIAA0319L", "KPNA1", "KPNA2", "KPNA4", "KPNA6", "LAMP1", "LAMP2", "LBR", "LMAN1", "LPCAT1", "MAN1A2", "MBOAT7", "MTOR", "NUP155", "NUP214", "NUP98", "NXF1", "OSBP", "OSBPL8", "PGRMC1", "PGRMC2", "PI4K2A", "PIP4K2C", "PMPCA", "PTDSS1", "RAB11B", "RAB24", "RABL3", "RANBP2", "RBM14", "RBM6", "RHOA", "RPN2", "RTN4", "SC5D", "SCAMP2", "SCD", "SGPL1", "SLC16A1", "SLC25A17", "SLC2A1", "SLC7A1", "SNU13", "SNX27", "SNX8", "SPNS1", "SPTLC1", "SPTLC2", "SRPRB", "STT3A", "STT3B", "STX18", "STX3", "STX5", "TMCO1", "TMEM192", "TMEM87A", "TMPO", "TNPO1", "VDAC1", "VDAC2", "VDAC3", "VMP1", "XPO4", "XPO6"]} \ No newline at end of file diff --git a/panther_protein_class/advanced/idx2term.json b/panther_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1d281ef6acfc60c8f73b4e8da2efb7af71816ee5 --- /dev/null +++ b/panther_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "transporter", "1": "oxidoreductase", "2": "protein modifying enzyme", "3": "secondary carrier transporter", "4": "membrane trafficking regulatory protein", "5": "glycosyltransferase", "6": "metalloprotease", "7": "serine protease", "8": "calmodulin-related"} \ No newline at end of file diff --git a/panther_protein_class/advanced/plot_0.png b/panther_protein_class/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..64e90cc84e77cb9d5c004adcf1bd5b7fdb1bcfe0 --- /dev/null +++ b/panther_protein_class/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ca569aa6a6f97d53f2a82332f9acf5acae8e54fceb4a4669556b4f2aa410d1b3 +size 205665 diff --git a/panther_protein_class/advanced/plot_1.png b/panther_protein_class/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..55211f40241325c3475b8d1d6c3fcca62f72c49c --- /dev/null +++ b/panther_protein_class/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fa3893605fed5bdf7657cf49331d4563abfef48ffd80048f070f76e72bdc7da9 +size 207943 diff --git a/panther_protein_class/advanced/plot_2.png b/panther_protein_class/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..510a50fe94e54f0882feb9bb69dacf5e2ea2b9f0 --- /dev/null +++ b/panther_protein_class/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9367c3303c7f09094bdc5ee729dc7103a9dbd5ee0318e09b548453bdf36955ec +size 198845 diff --git a/panther_protein_class/advanced/plot_3.png b/panther_protein_class/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..27b34b5da76216fe3b95afe3645602b716c09f92 --- /dev/null +++ b/panther_protein_class/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5f92118695b50a95f1f54326acb1c14c32158cce5324b10fc1dbd5daf32552f9 +size 197616 diff --git a/panther_protein_class/advanced/plot_4.png b/panther_protein_class/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..3ba28db954643039a6a4d661f4e0359865a309e5 --- /dev/null +++ b/panther_protein_class/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:034e631b50179ef84f7ec6c82f5e7afd3c389fad0273d0152ffa01dd349d95e9 +size 203918 diff --git a/panther_protein_class/advanced/plot_5.png b/panther_protein_class/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..e06ded363e47015f63864ba68f996d927a57e722 --- /dev/null +++ b/panther_protein_class/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b64f0fae629e782d85bf1db36f6a5ab4fb594061e06b80433ab790dddb28ebbd +size 198590 diff --git a/panther_protein_class/advanced/plot_6.png b/panther_protein_class/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..103213fcc05e7a4338966e9f31a275e618f0ce2d --- /dev/null +++ b/panther_protein_class/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:35124323f9bbfc1c0bae3d6879dc60cab40c2056420670c3ad6782d429cacd33 +size 197625 diff --git a/panther_protein_class/advanced/plot_7.png b/panther_protein_class/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..e7d92cde8f0c87a9b656459fe82a2180a49c5b42 --- /dev/null +++ b/panther_protein_class/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:afbec128d4044f1dafa940f864b76c98cc17a1044e5929cbe6e12fd3d6e80ebd +size 195199 diff --git a/panther_protein_class/advanced/plot_8.png b/panther_protein_class/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..d86990c929dc4d0ff87a5603ca054f4a47170a1c --- /dev/null +++ b/panther_protein_class/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9eff71ed85caa8b17ea0c89788356bece92f7e019e0182465230cd583882130e +size 194432 diff --git a/panther_protein_class/basic/idx2term.json b/panther_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..824818edec92b0fda1317e48d94d0e7985a870c0 --- /dev/null +++ b/panther_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "transporter", "1": "oxidoreductase", "2": "protein modifying enzyme", "3": "secondary carrier transporter", "4": "membrane trafficking regulatory protein", "5": "glycosyltransferase", "6": "metalloprotease", "7": "serine protease", "8": "calmodulin-related", "9": "oxidase", "10": "SNARE protein", "11": "acyltransferase", "12": "nucleic acid metabolism protein", "13": "ATP-binding cassette (ABC) transporter", "14": "primary active transporter", "15": "transferase", "16": "RNA helicase", "17": "scaffold/adaptor protein", "18": "membrane traffic protein", "19": "chaperone", "20": "kinase"} \ No newline at end of file diff --git a/panther_protein_class/basic/plot_0.png b/panther_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..77995460a5f568bdad71df7cbf7ce4538052e575 --- /dev/null +++ b/panther_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a8dddc987af56daeb8e35153fda8bb538e93a52884c1f417c4a03ae4e1aa4dfe +size 136754 diff --git a/panther_protein_class/basic/plot_1.png b/panther_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..f05eb70dba78a10083dab5641969c0bc8e0118c4 --- /dev/null +++ b/panther_protein_class/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e013d411f2bb7809efc8b39f665d459a7e50703434a4f6f2035971886ae92706 +size 139892 diff --git a/panther_protein_class/basic/plot_10.png b/panther_protein_class/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..77907be0458b0260c6f05b7aa0387c3ab1c50679 --- /dev/null +++ b/panther_protein_class/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bcc46199c2dff20af2f5461107cee711fc9e324fe640cdec525263c40dd925f2 +size 130939 diff --git a/panther_protein_class/basic/plot_11.png b/panther_protein_class/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..cb5648c2f6cc60d8b64397d46549f9e90f474844 --- /dev/null +++ b/panther_protein_class/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c294fe3d509740de53d3992c385eb32bdca523127afa2328d3e93ed67567869e +size 139829 diff --git a/panther_protein_class/basic/plot_12.png b/panther_protein_class/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..9647765362d9cd6233552f948caac58d08d0a1ab --- /dev/null +++ b/panther_protein_class/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:62f9a58337c1b59c034be4206ac1cf69c50b684e19ce5f854d96a933a99da235 +size 136244 diff --git a/panther_protein_class/basic/plot_13.png b/panther_protein_class/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..440ae4f05d85116b79bad8afd2e716cdb63f8d3c --- /dev/null +++ b/panther_protein_class/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:991cf648f00498d05755b87c3c89b4639d71edb28b6b2a589caa90cc67d27a48 +size 143325 diff --git a/panther_protein_class/basic/plot_14.png b/panther_protein_class/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..e55df76539d34458a043c9b1b033f4a4da5590de --- /dev/null +++ b/panther_protein_class/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:048170a55fda3072aaad181dcfdd25edade1ac3d341016a55be8296c587801ec +size 140367 diff --git a/panther_protein_class/basic/plot_15.png b/panther_protein_class/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..b653669a6b723645d3e80e22aeade5d397794411 --- /dev/null +++ b/panther_protein_class/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:405961f39019c4998f20479f7abbbb0d23ab031ef5622eb7efb7f5fd47db7500 +size 135600 diff --git a/panther_protein_class/basic/plot_16.png b/panther_protein_class/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..a4eab348596fcd6c7912d6075d83ab4c7afa9d3b --- /dev/null +++ b/panther_protein_class/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eeecb37654c198e6a41bff3dbed37167519284fe39a0241045fb438fc5fd9840 +size 134388 diff --git a/panther_protein_class/basic/plot_17.png b/panther_protein_class/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..2cc1019f161baed1612f636ec66eaae47f198fc6 --- /dev/null +++ b/panther_protein_class/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f3d825c26702281c329e629d203947a9b12d9f020f04d38285909b46061e2844 +size 150236 diff --git a/panther_protein_class/basic/plot_18.png b/panther_protein_class/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..537c396fa4827f17ae5365e79f981db7b645e361 --- /dev/null +++ b/panther_protein_class/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f50536c2028de3ba0ab9ba2e7acf6a36f99252dc9e6acdddfe5c59cad3916def +size 152110 diff --git a/panther_protein_class/basic/plot_19.png b/panther_protein_class/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..a36a4e080d75a3249d2e5cfde278d4be5c533373 --- /dev/null +++ b/panther_protein_class/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:adb2824dc29b4b689e24ab4fbfecae0f17f14b18d15ad5e3dc355a9fd7cd2b71 +size 142394 diff --git a/panther_protein_class/basic/plot_2.png b/panther_protein_class/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..db0170634a247889f43357721aa8f287c70a6004 --- /dev/null +++ b/panther_protein_class/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:50bf34534cc0367d3e25e3260f605f20a225e92724b7686e540395a33d9745f8 +size 141498 diff --git a/panther_protein_class/basic/plot_20.png b/panther_protein_class/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..ddbed177b737cf3a0f37512f9946c794a3b33a59 --- /dev/null +++ b/panther_protein_class/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bff481e96b835f80c48ec982d2d5df4e097840b42f5eb01b072b8395f28c4f3b +size 134012 diff --git a/panther_protein_class/basic/plot_3.png b/panther_protein_class/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..5b32786f953d776ea8553937e74a653a2907da88 --- /dev/null +++ b/panther_protein_class/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:67de75fbe723a62f40a12e3fafaee1f4774b251b0a406fbd338e4453edd0e045 +size 145300 diff --git a/panther_protein_class/basic/plot_4.png b/panther_protein_class/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..281f969713837191dbc89224f107217281ded6e1 --- /dev/null +++ b/panther_protein_class/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9e7918b02db88f38208c61eb2c803e62ec40eb6b5f5ecfe42db37698644876cc +size 145694 diff --git a/panther_protein_class/basic/plot_5.png b/panther_protein_class/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..7f6044b993231cd6b20dfeaddb70b2ab8c87d953 --- /dev/null +++ b/panther_protein_class/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:729f9532e22eed437ce7064affb14690a3b61e540f3f37ea1b09a167e9835e26 +size 139028 diff --git a/panther_protein_class/basic/plot_6.png b/panther_protein_class/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..0a9ed184fc821550a8c4186084111453215480e8 --- /dev/null +++ b/panther_protein_class/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:71087a025b7f8e0344c60a15fb9f2d832db3eac5883acaef4689b53b3889b586 +size 135067 diff --git a/panther_protein_class/basic/plot_7.png b/panther_protein_class/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..a8f7587fed554a7fede72bf00b2c599aa4a1ca4d --- /dev/null +++ b/panther_protein_class/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a9f20c9f80cdd5c24710cdace6f71d3ae1e2ce8e8c7da5b555f06c2642369366 +size 134331 diff --git a/panther_protein_class/basic/plot_8.png b/panther_protein_class/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..7339e2a58ced2b1d549b4509db20779fece872c5 --- /dev/null +++ b/panther_protein_class/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b0ff77b15b97289d19114279fe33e24e54390f860190f505a896d38a2c0dbd41 +size 132979 diff --git a/panther_protein_class/basic/plot_9.png b/panther_protein_class/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..584073830b4ae12a2edf83a02a256e847ec8ea08 --- /dev/null +++ b/panther_protein_class/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7350c71217e3bceccb05f9bd67bc202a7be39742b5f389aa0a497a982b2a058c +size 130157 diff --git a/panther_protein_class/consensus.joblib b/panther_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..9ab304b66bb007877ac0e8ecc7c4443b5e033141 --- /dev/null +++ b/panther_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:38a1f288b372a7837a52eacca7f36b3280a41880233a3cbe493cd24481587c2d +size 96301 diff --git a/panther_protein_class/df_merge.tsv b/panther_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..68704adebce90dc2be7c944437d82af68bcd599a --- /dev/null +++ b/panther_protein_class/df_merge.tsv @@ -0,0 +1,14 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +transporter 25 56 4.318028340484641 1.574292196937499e-05 16.281553398058254 57.34708737864078 1.7781248355514696 0.2510912048406951 6.627271511266295 3.5084386843827997 1.4364723564792363 0.3433005081320681 1.448525232325282e-07 0.0002562264911922 0.0001452233176726 1.4748401510685188e-07 3.269431397147984e-06 +oxidoreductase 19 43 3.4926287267883707 0.0004782910032201 12.558252427184469 43.60436893203884 0.9664652969079414 0.3656199292680728 5.072676172192643 3.8442089013841825 1.3118377214144643 0.3470065139863294 0.016904458337182 0.0011734825476199 0.0140469368115112 0.0084996601315941 4.940712794977583e-05 +protein modifying enzyme 12 26 3.101550620429467 0.0019250995487103 6.487864077669903 24.82281553398058 0.9737051724681342 0.3238157719208961 2.575528657386725 2.871041189126622 1.1448244681235864 0.2930923238696635 0.0054117803203034 0.2486824788491954 0.0191373699896123 0.0133513277547448 3.0774644792985268e-06 +secondary carrier transporter 12 15 2.915082119450964 0.0035559496214603 6.104368932038835 14.6626213592233 1.264699085385324 0.2718921136589474 3.483843477892234 2.781747184831951 1.2916784116683784 0.322278600042778 0.0481228952273266 0.0472622034410549 0.0323757559425281 0.0294581500767194 0.0564249445308771 +membrane trafficking regulatory protein 5 20 2.7395473339041856 0.0061523854993943 4.949029126213592 18.78640776699029 1.0645815505395402 0.2320552342124929 2.3097144002673033 2.893415643517755 1.4460865220385617 0.2677048300346334 0.0034468330488433 0.2298835505782255 0.0150469902773183 0.0092216123798009 0.0426924060067812 +transmembrane signal receptor 4 7 2.5251689610843444 0.0115642675219744 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 0.1148328733336154 0.3651094145888684 0.2280025569563264 0.0743165580351533 0.4658609742937001 +glycosyltransferase 14 23 2.413651669184316 0.0157935531375963 6.910194174757281 21.383495145631063 0.4532445654278834 0.4839054526936805 3.459080207891436 3.770544939817097 1.1075266664550316 0.3364357117884409 0.3956678434237156 0.3295231102555642 0.5513512032975088 0.3172642531290227 0.0426994651036757 +oxygenase 4 8 2.310607001595112 0.0208545721645085 3.138349514563106 6.771844660194175 1.5409868347565758 0.1477866581414416 1.2914149665013366 1.041089559555361 1.2379399582807478 0.2357869798067575 0.0040835015588921 0.1114073342812727 0.0228441699597423 0.00251045639703 0.0052582215982291 +metalloprotease 10 27 2.208460637092806 0.02721217885869 8.58495145631068 26.398058252427184 1.4262736372921438 0.246779453311036 3.321022586051017 1.6463540525991265 1.1083706824215755 0.2918245458017476 0.0170604140358183 0.2336798458054532 0.0158208073938894 0.0099653014460593 0.0010655904765625 +serine protease 7 18 2.1927818637491425 0.0283230992395051 5.662621359223301 17.516990291262136 1.1445634795625386 0.1820139001244477 2.0809494011218104 1.6626107291843584 1.568325484830445 0.2384821649427795 0.0115084565191122 0.2145132052110039 0.3837477700803094 0.0066284009542843 0.0022946198906289 +mitochondrial carrier protein 4 6 2.112937287801679 0.0346061358326725 3.2936893203883497 7.065533980582524 1.4583792806536486 0.1840967072966826 2.0141872967986307 1.116111686789906 1.1161599809390137 0.2507152229846449 0.0003500834863265 0.0619434524836269 0.0069232563631819 0.0002086676392486 0.0002481332774246 +calmodulin-related 6 14 2.0799597823328577 0.0375292218751706 5.053398058252427 12.385922330097088 1.3935892727836532 0.1814075830019033 2.0222219603900085 1.786979844553702 1.206053991839631 0.2252292235861566 0.0047560301820082 0.1157751708195439 0.0246740936940832 0.002932051876052 0.0001380877092489 +transfer/carrier protein 4 9 2.0288936526576884 0.0424691234172667 4.33252427184466 11.024271844660197 0.5751131114698911 0.3717158985009051 2.2946984989028927 1.3525930522279908 1.248808855129494 0.3186564966906889 0.0040835015588921 1.0 0.0228441699597423 0.00251045639703 0.0052582215982291 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6e8f8f31b0c49f96ec15396104b061fea5afca6a --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 156, + "title": "Average number of proteins per term", + "value": 14.89102564102564 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..456d0a0925ddc55f4dcb055a0fd2fc5caa469b89 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..7200581c723cb2de5ebeb54288b2ca7fafd9c2e3 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,46 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +transporter 0.6162531613112259 4.318028340484641 1.574292196937499e-05 0.0024529018665813 0.0024558958272226 56 P53985,O60830,Q567V2,Q7Z3B4,Q99567,Q9Y619,Q9H2V7,Q9H2D1,O43681,Q15070,O43615,O60684,O15397,Q99595,Q92973,Q9C0E2,Q9Y584,O43772,Q9HD45,Q8N1F7,Q9HAV4,Q12769,P52294,Q92544,Q9NR77 25 +oxidoreductase 0.5592591716723615 3.4926287267883707 0.0004782910032201 0.0719143411421992 0.0106590566431922 43 P51970,O43169,Q8N0U8,O95168,O43676,Q6DKJ4,Q16134,O14949,O15254,P00403,O95831,O75306,Q86Y39,Q15067,Q9Y6M9,P16435,O96000,Q8N4Q0,Q08431 19 +protein modifying enzyme 0.6569909385490169 3.101550620429467 0.0019250995487103 0.2596298164095972 0.0273014117817103 26 O60725,Q15418,Q86YN1,O60476,O14744,O15460,Q6P2P2,P50897,O75718,P13674,Q92791,O60568 12 +galactosidase 0.9200700116686042 3.0568812705975854 0.0022365284505856 0.294810826985916 0.0290748698576133 2 P16278 1 +secondary carrier transporter 0.775706310846754 2.9150821194509637 0.0035559496214603 0.4263390737357032 0.0380756208575549 15 O75746,P55011,Q96ES6,O14975,Q9UBX3,Q9UJS0,Q9BXP2,O95202,Q8TB61,Q9Y6M7,Q9BQT8,Q15043 12 +membrane trafficking regulatory protein 0.6611903438570507 2.7395473339041856 0.0061523854993943 0.6181535627279171 0.0533206743280843 20 O43731,P24390,Q8WTV0,P13473,Q14108 5 +voltage-gated ion channel 0.910417274584172 2.6045191611722065 0.0092003276372696 0.7635206238412259 0.0683452910197173 3 P21796,P45880 2 +transmembrane signal receptor 0.8795153599912451 2.5251689610843444 0.0115642675219744 0.8370868389376405 0.0784359014533921 7 Q8WUJ1,Q99720,O15173,O00264 4 +glycosyltransferase 0.5901877745190838 2.4136516691843157 0.0157935531375963 0.916545827767505 0.0949429915071231 23 P46976,O60762,Q8N4A0,Q10472,Q9BT22,P04844,Q96L58,Q8TCJ2,O60512,P46977,Q8NAT1,P04843,O43909,Q9H0U3 14 +oxygenase 0.7822259272760143 2.310607001595112 0.0208545721645085 0.9626609515305292 0.1084437752554446 8 Q16850,P09601,P30519,Q14534 4 +kinase activator 0.7473745624270727 2.241251379249401 0.0250097964428093 0.9807673415551283 0.1219227576586954 2 O95067 1 +metalloprotease 0.5301072623256629 2.208460637092806 0.02721217885869 0.986484644677094 0.1248558794692839 27 O75844,Q99797,Q10713,P42892,Q9UIQ6,O95630,Q5JRX3,Q6P179,Q9NZ08,Q9BYT8 10 +serine protease 0.6044246013064571 2.1927818637491425 0.0283230992395051 0.9886912902897996 0.1262400994675087 18 Q2T9J0,O14773,P10619,Q9HB40,Q9H3G5,P67812,P42785 7 +major histocompatibility complex protein 0.8852889667250365 2.1392055320979617 0.0324190263571333 0.9941491104369934 0.1388256400000334 4 P01889,P04439,P55899 3 +mitochondrial carrier protein 0.8368882963345783 2.112937287801679 0.0346061358326725 0.9958893799441936 0.1400563895649536 6 Q70HW3,Q9Y6C9,Q9BSK2,Q00325 4 +calmodulin-related 0.648751074713782 2.0799597823328577 0.0375292218751706 0.9974387132054452 0.1400563895649536 14 O43852,P80303,Q14257,Q9BRK5,Q02818,P41208 6 +transfer/carrier protein 0.7127297288273384 2.0288936526576884 0.0424691234172667 0.9988522830522748 0.1540740291417118 9 O15127,P17900,Q9Y5M8,P12235 4 +oxidase 0.5991404346481635 1.95372283312884 0.0507340044866568 0.9997031643012044 0.168393717019542 16 P14406,Q6ZRP7,P14854,P13073,O75845,Q15800,Q8NB78 7 +SNARE protein 0.6843950905903001 1.813435309702504 0.0697647076823837 0.9999873968614712 0.2176658879690372 8 Q86Y82,Q13190,Q9P2W9,Q13277,O95249,Q9UNK0,P51809 7 +G-protein coupled receptor 0.791717477173605 1.7432975531543626 0.0812816525572928 0.9999981951015112 0.2438449576718784 4 Q9NPR9,Q5VW38 2 +acyltransferase 0.5017831707454468 1.6200157579433012 0.105228891954026 0.9999999706867096 0.280833329740028 20 P23786,Q9NUQ2,Q9BWD1,O15228,Q8NCC3,P35610 6 +phospholipase 0.6061021362658062 1.5888052957703442 0.1121043572963857 0.9999999912004542 0.2866931104628882 11 Q8IV08,Q8N2A8,Q8NHP8 3 +amino acid transporter 0.7408111747516001 1.522726483641208 0.1278271492871598 0.9999999994579992 0.3115786763874522 4 O14925 1 +nucleic acid metabolism protein 0.66430052567296 1.5015769071203091 0.1332064109830963 0.9999999997935344 0.3144445910789828 7 Q9Y2W1,Q8IWR0,P49750,Q9Y580,Q96FV9 5 +ATP-binding cassette (ABC) transporter 0.5878026868662415 1.4184581471701403 0.156057049557954 0.9999999999968022 0.3289851315005518 10 P08183,O14678,Q03519,Q03518,Q9NUT2 5 +tubulin 0.6703081321686463 1.3516252116618372 0.1764952408684323 0.9999999999999302 0.3574177755385976 6 P04350,P07437,Q13885,P68371 4 +Hsp90 family chaperone 0.6776489007317615 1.3125148002022693 0.189346495665291 0.999999999999994 0.3646673249850049 5 Q58FF6,P14625,P07900 3 +glycosidase 0.6406333813416316 1.145048839723681 0.2521889264547416 1.0 0.4420390171566258 5 Q9BTY2 1 +translation factor 0.5442226219576837 0.9060058739392022 0.3649327434019191 1.0 0.5750455350575696 7 P51116,P51114 2 +primary active transporter 0.3721445173275959 0.7325037864212176 0.4638611324807002 1.0 0.6700216358054559 23 P20020,Q8N4H5,Q9NS69,Q6P4A7,Q9BUN8,P16615,O60888,Q6NTF9,Q9Y5J7,Q96NB2 10 +transferase 0.3311396990992314 0.7011625140180132 0.4832016007744883 1.0 0.6832054757587044 32 Q7LGA3,O15217,P37268,P43490,Q06520,Q2TAA5 6 +RNA helicase 0.4239207266263793 0.6895034619182546 0.4905064954165057 1.0 0.6832054757587044 14 Q9H2U1,Q9H6S0,Q08211,Q7Z478,Q7L2E3,Q14562,Q92620 7 +nucleotide phosphatase 0.5265179239423845 0.642983089946806 0.5202350724465634 1.0 0.6979438224482232 5 P49902 1 +esterase 0.4443896749839432 0.590565495824586 0.5548115894366203 1.0 0.7212550662676064 9 Q969T7,Q9NUJ1 2 +ATP synthase 0.3543709404488052 0.534582479717797 0.5929386014140152 1.0 0.7644497671122841 20 P24539,Q9Y487,O75964 3 +scaffold/adaptor protein 0.2570903471672475 0.4708514322825685 0.637746832988197 1.0 0.7895913170330058 95 Q9H3F6,Q8N3C0,Q9Y5X2,P35613,Q9UQB8,Q9ULX6,Q9NZW5,Q9BQ95,Q9UGP8,Q8IZ81,O43572,P07602,Q8IZP0,Q9Y2W6,P46108,Q7L576,Q14168,Q5VYK3,Q96L92,O94915,P49792,Q5BKZ1,Q9Y5W7,O14936,Q9Y2I1,Q96PV6,P57105,Q14BN4,Q96CX2,Q9Y5V3,Q96AG4 31 +lyase 0.3816669711343914 0.3775163863261936 0.7057898892013028 1.0 0.8535133543829709 12 Q9UHG3,P22830,P53701 3 +membrane traffic protein 0.2583009139352749 0.262103916625624 0.793241327282642 1.0 0.9166344226377195 66 Q96PC5,P51572,P43307,Q12768,Q96RL7,P40855,Q9UPT5,P49257,Q9H223,Q9NX40,Q99523,A6NIH7,O60313,Q9Y2T2,Q96D71 15 +chaperone 0.2534360353343494 0.2409286429995852 0.8096104220148601 1.0 0.9218921593745852 69 P46379,Q9Y2G8,O15260,Q16543,Q9Y2R0,Q9NWM8,Q9Y680,P49321 8 +kinase 0.2992423720570569 0.1910683713827949 0.8484720270801509 1.0 0.952241987226644 20 Q8WVC6,P52429,P52789,Q9BRR6,Q8TBX8 5 +DNA helicase 0.3285998390866025 0.1340688689582782 0.8933481163363333 1.0 0.974561581457818 11 P46063,P18074,P28370 3 +hydrolase 0.2710992431920906 0.067347592410639 0.9463049896001516 1.0 0.9974566106596192 23 P15586,P07099,O60502,Q99519 4 +damaged DNA-binding protein 0.2932594105631855 0.0422290169668944 0.9663161309920658 1.0 1.0 3 P54727,P54725 2 +microtubule binding motor protein 0.2657264533037459 0.032968689538734 0.9736995561900073 1.0 1.0 20 Q9UJW0,O75935 2 +histone modifying enzyme 0.275129107560455 0.03295857471624 0.973707622267216 1.0 1.0 17 O14929 1 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..599f4a02eddd73bb37f7fbced6b56c034223d5d5 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "Lambda repressor-like transcription factor", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "Rel homology transcription factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "amylase", "apolipoprotein", "aspartic protease", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "hydroxylase", "immunoglobulin receptor superfamily", "integrin", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT4", "AGPAT5", "AGTPBP1", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP10", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMPD2", "ANAPC1", "ANAPC7", "ANKFY1", "ANKHD1", "ANKRD17", "ANKS1A", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APIP", "APOL2", "APP", "APRT", "ARAP1", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP18", "ARHGDIA", "ARHGEF1", "ARHGEF7", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL6IP5", "ARMC9", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD2", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATL2", "ATL3", "ATM", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B4GALT3", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAP18", "BAZ2A", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCKDHB", "BCKDK", "BCLAF1", "BCR", "BDH2", "BECN1", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRIX1", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBFB", "CBL", "CBR1", "CBX8", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2BP2", "CD3EAP", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC6", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2AIP", "CEBPZ", "CENPB", "CEP170", "CEP250", "CEP97", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHM", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHTF18", "CHUK", "CIT", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLIP1", "CLK3", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNP", "COA3", "COASY", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX7A2", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC22", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAKD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DEK", "DENR", "DERA", "DERL1", "DERL2", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIMT1", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUS2", "DUS3L", "DUSP12", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "ENY2", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERH", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETHE1", "EWSR1", "EXO1", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EZR", "FAHD1", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP14", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FSD1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALE", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GID8", "GINS1", "GINS2", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNB1L", "GNE", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOSR1", "GOT1", "GOT2", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACL1", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK1", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90AB4P", "HSP90B1", "HSPE1", "HTATSF1", "HUS1", "HUWE1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INTS11", "INTS6", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BP1", "IRF2BPL", "ISG20L2", "ISOC1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KCTD10", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KLC2", "KLC4", "KMT2A", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LENG8", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT4", "LRP1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRFIP1", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTN1", "LYAR", "LYPLA1", "LYPLA2", "LZTFL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MBOAT7", "MCCC1", "MCCC2", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED4", "METAP2", "METTL13", "METTL25", "METTL7B", "MFAP1", "MFGE8", "MFSD3", "MFSD5", "MGEA5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU2", "MID1", "MIF", "MINPP1", "MIPEP", "MMAB", "MMS19", "MOCS3", "MOGS", "MON2", "MORF4L1", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFR", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCDN", "NCKIPSD", "NCOA5", "NCOR1", "ND1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEDD4", "NEDD4L", "NENF", "NET1", "NEU1", "NF1", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME3", "NME7", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B2", "PAFAH1B3", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PARG", "PARN", "PARP1", "PARP2", "PARS2", "PATL1", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDXP", "PEBP1", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF3", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PICALM", "PIK3C2A", "PIK3R2", "PIK3R4", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PMVK", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "POMP", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF18", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RAF1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RARS2", "RASAL2", "RAVER1", "RB1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBM47", "RBM7", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIOK1", "RIOK2", "RIPK1", "RNASEH2A", "RNF2", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSU1", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SALL2", "SAMHD1", "SAP18", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SC5D", "SCAF1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL1", "SCYL2", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFMBT1", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGK3", "SHMT1", "SHMT2", "SHPRH", "SIGMAR1", "SIN3A", "SIPA1", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC35B2", "SLC39A14", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLMAP", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC6", "SMG5", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX14", "SNX2", "SNX27", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPNS1", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STK4", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNJ2BP", "TAB1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAOK1", "TAP1", "TAP2", "TAPBP", "TARBP1", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TCP11L1", "TDRKH", "TECR", "TERF2IP", "TES", "TFB1M", "TFB2M", "TFCP2", "TFG", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TM7SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM87A", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMX2", "TNPO1", "TNPO2", "TNPO3", "TNRC6A", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRAF2", "TRAP1", "TRAPPC4", "TRIM26", "TRIM27", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTC28", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBR1", "UBR2", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UGDH", "UGGT1", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNG", "UPF2", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP32", "USP34", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP3", "UTP6", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VBP1", "VDAC1", "VDAC2", "VDAC3", "VKORC1L1", "VMP1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "WARS", "WASF2", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR4", "WDR74", "WDR82", "WNK1", "WWP2", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YLPM1", "YME1L1", "YTHDC2", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZC3H7B", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF326", "ZNF598", "ZNF622", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB8", "ABCD4", "ABHD10", "ABI1", "ACAT2", "ACOX1", "ACOX3", "ADPGK", "AGPAT5", "AIFM1", "AKAP10", "AKAP8L", "ALG1", "ALG11", "AP3M1", "ASCC3", "ASNA1", "ATP2A2", "ATP2B1", "ATP5F1", "ATP5L", "ATP6V0A2", "B3GALT6", "B4GALT3", "BAG6", "BAIAP2", "BCAP31", "BSG", "CALU", "CASK", "CCNB2", "CDC37", "CETN2", "COA3", "COX2", "COX4I1", "COX6B1", "COX7A2", "CPT2", "CPVL", "CRK", "CRTAP", "CTSA", "CUTA", "CYB5B", "CYB5D2", "CYFIP1", "CYP51A1", "DCAKD", "DCTN3", "DCTN4", "DERL1", "DGKE", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DNAJC16", "DOLPP1", "DPM1", "ECE1", "ECSIT", "EHD4", "ELMOD2", "EPHX1", "ERAP1", "ERAP2", "ERCC2", "ETFDH", "EXOC7", "EXTL3", "FCGRT", "FDFT1", "FECH", "FKBP14", "FKBP7", "FRYL", "FUCA2", "FXR1", "FXR2", "GALNT1", "GALNT4", "GLB1", "GM2A", "GNPAT", "GNS", "GOSR1", "GPR107", "GPR108", "GSTA4", "GYG1", "HAT1", "HCCS", "HK2", "HLA-A", "HLA-B", "HMOX1", "HMOX2", "HS2ST1", "HSP90AA1", "HSP90AB4P", "HSP90B1", "ICMT", "IPO8", "KCTD10", "KCTD12", "KDELR1", "KDELR3", "KDM1B", "KIAA0368", "KPNA1", "KPNA6", "LAMP2", "LENG8", "LETM1", "LMAN1", "LNPEP", "LRRC59", "MAGED1", "MAGT1", "MAN1A2", "MFGE8", "MFSD3", "MGEA5", "MIA2", "MIPEP", "MPP2", "MPP6", "MPV17L2", "MSMO1", "MTCH2", "NAMPT", "NASP", "NDUFA11", "NDUFA8", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEU1", "NISCH", "NLN", "NT5C2", "NT5C3B", "NUCB1", "NUCB2", "NUP160", "NUP54", "NUP88", "NUP93", "NXN", "OCIAD1", "OPA1", "OXA1L", "P3H4", "P4HA1", "P4HA2", "PCYOX1", "PEX19", "PGRMC1", "PGRMC2", "PIP4K2C", "PITRM1", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLOD3", "PMPCA", "POMGNT2", "POR", "PPT1", "PRCP", "PRMT5", "PRMT9", "PSAP", "PXMP2", "QSOX2", "RAD23A", "RAD23B", "RANBP2", "RBM7", "RCN2", "RECQL", "REPS1", "RHBDD2", "RPN1", "RPN2", "RPS6KA1", "SC5D", "SCAMP2", "SCARB1", "SCARB2", "SCPEP1", "SDF4", "SEC11A", "SEC63", "SFXN2", "SFXN4", "SIGMAR1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC27A2", "SLC35B2", "SLC39A14", "SLC4A7", "SLMAP", "SMARCA1", "SNX14", "SNX27", "SNX8", "SOAT1", "SORT1", "SPNS1", "SQLE", "SRPRB", "SSR1", "STAMBP", "STT3A", "STT3B", "STX12", "STX18", "STX3", "STX5", "STX8", "SULT2A1", "SURF4", "SYNJ2BP", "TAP1", "TAP2", "TDRKH", "THOC1", "THRAP3", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM9", "TM9SF3", "TM9SF4", "TNPO1", "TOMM22", "TOMM5", "TPP1", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TYSND1", "UNC119B", "UQCRQ", "VAMP7", "VDAC1", "VDAC2", "VKORC1L1", "VPS13A", "WASHC5", "XPO4", "XPO5", "YLPM1", "YTHDC2", "ZADH2", "ZC3H7A", "ZMPSTE24", "ZNF326"]} \ No newline at end of file diff --git a/pharos_dto/advanced/idx2term.json b/pharos_dto/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..729dd127dec02e62300723c7bc4ef7e3b7836dd2 --- /dev/null +++ b/pharos_dto/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter", "1": "SLC superfamily of solute carriers", "2": "SLC25 family of mitochondrial transporters", "3": "Calmodulin", "4": "Intracellular calcium-sensing protein", "5": "Receptor", "6": "Calcium-binding protein", "7": "Mitochondrial nucleotide transporter subfamily", "8": "Glycosyltransferase", "9": "Signaling"} \ No newline at end of file diff --git a/pharos_dto/advanced/plot_0.png b/pharos_dto/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..402a47d65eceaf3d2281bbfacb1e2c1265fd875a --- /dev/null +++ b/pharos_dto/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0ca9665393ae3dc05d003070eb237bcaf33173e396ab013d341da7b3bb117ad3 +size 221578 diff --git a/pharos_dto/advanced/plot_1.png b/pharos_dto/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..57c61dc3483f02cfba262c8e258e4116f762d7bc --- /dev/null +++ b/pharos_dto/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c6749cc86f796af04bfc716439447bd209ec0b1531bc7b53bdb9899f63f48fd7 +size 205330 diff --git a/pharos_dto/advanced/plot_2.png b/pharos_dto/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..f1ec5638a2b548deb94f19faf99ba040610d9795 --- /dev/null +++ b/pharos_dto/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6f36ef68912a489670c439b2b612abbd26c53ad3b363cc7f14f221a65cb66adc +size 198779 diff --git a/pharos_dto/advanced/plot_3.png b/pharos_dto/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..49195c1c15206bac49c97d7cbe585430d8e671bf --- /dev/null +++ b/pharos_dto/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ac53741b4bc44111e907bdd51439060cc007b40d7128a0258a96d02efa32029f +size 198004 diff --git a/pharos_dto/advanced/plot_4.png b/pharos_dto/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..5ea38f7a45d14b27346943f5d6adbd1d4d07e926 --- /dev/null +++ b/pharos_dto/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:201ee0cb00bdd0e2340a2a4e7eb3c49e095901ab71ba15ec746d522a14b4d293 +size 202295 diff --git a/pharos_dto/advanced/plot_5.png b/pharos_dto/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..346d63a1e9d881d32a9e6ab7c89af06a227b36fc --- /dev/null +++ b/pharos_dto/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0e4d2a69a5dc5c35dd7f950b8cd9637d63211ab94dfa9a111e96b5ce0c124d00 +size 208925 diff --git a/pharos_dto/advanced/plot_6.png b/pharos_dto/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..001f0d73c860612cfbd264b45f62be4dc9ec2eea --- /dev/null +++ b/pharos_dto/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c941d075d701e6225bc6aad55c18373f9e96082ecf24f7c46bb1e9988cef2755 +size 203623 diff --git a/pharos_dto/advanced/plot_7.png b/pharos_dto/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..9d0f27014006031baeb8b1a22eb3cb2f64431bd9 --- /dev/null +++ b/pharos_dto/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:93ffb3679eba55639fed20b0cd95c963f2eacb7d3bff20f0d42113e1efb054a7 +size 194582 diff --git a/pharos_dto/advanced/plot_8.png b/pharos_dto/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..26716ad779f4a77887b05fa16cb8b891251e7a86 --- /dev/null +++ b/pharos_dto/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b4c354b13b5e9701ed6e9ee4ea67d551dddf68155b349f644e7505dd240030c7 +size 199951 diff --git a/pharos_dto/advanced/plot_9.png b/pharos_dto/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..c084790c926102f3633c06d58c11202fff4cc9d4 --- /dev/null +++ b/pharos_dto/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:324ef93fab5d641c1cb10784076b0dc162c87ec8121054e03faaff4cd588b785 +size 199780 diff --git a/pharos_dto/basic/idx2term.json b/pharos_dto/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a12a8818c2cb5ec87fc2b4a95cc1b5d60a865c02 --- /dev/null +++ b/pharos_dto/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transporter", "1": "SLC superfamily of solute carriers", "2": "SLC25 family of mitochondrial transporters", "3": "Calmodulin", "4": "Intracellular calcium-sensing protein", "5": "Receptor", "6": "Calcium-binding protein", "7": "Mitochondrial nucleotide transporter subfamily", "8": "Glycosyltransferase", "9": "Signaling", "10": "Atypical group", "11": "Oxidase", "12": "SNARE protein", "13": "ATP-binding cassette transporter family", "14": "Metalloprotease", "15": "Protease", "16": "Serine protease", "17": "Oxidoreductase", "18": "Reductase", "19": "mRNA splicing factor", "20": "Epigenetic regulator", "21": "Transferase", "22": "Hydrolase", "23": "Helicase"} \ No newline at end of file diff --git a/pharos_dto/basic/plot_0.png b/pharos_dto/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..5ba4ca7658aba80839ef9646667da2fc5c1c4aa0 --- /dev/null +++ b/pharos_dto/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3ac793ec871dd46a952368f48b28ceede41d3c11898e51fa8744d1f293ae9a44 +size 143330 diff --git a/pharos_dto/basic/plot_1.png b/pharos_dto/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..0c03cf3848bfe64a81547bcdc766b7366bb5c9a0 --- /dev/null +++ b/pharos_dto/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1b172c172cd9f2ab0c100bfce0729d99b5ff52a38dcd9a109ea385a481430908 +size 147486 diff --git a/pharos_dto/basic/plot_10.png b/pharos_dto/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..7fb8bf5f4883e80d57b828e23b2a1df0c1db1835 --- /dev/null +++ b/pharos_dto/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:66176feff3f1e819f6e998501fc57606a9f0d9fc31f215fa0c1e131c6cc6580b +size 129624 diff --git a/pharos_dto/basic/plot_11.png b/pharos_dto/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..1eab785e3b15cc0992893b986d872d589ca4c3b9 --- /dev/null +++ b/pharos_dto/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1c72cbd6a2e254323b36a7bb8b492755669a1132d1cb93fb0c74d49faece868c +size 128030 diff --git a/pharos_dto/basic/plot_12.png b/pharos_dto/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..77907be0458b0260c6f05b7aa0387c3ab1c50679 --- /dev/null +++ b/pharos_dto/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bcc46199c2dff20af2f5461107cee711fc9e324fe640cdec525263c40dd925f2 +size 130939 diff --git a/pharos_dto/basic/plot_13.png b/pharos_dto/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..9844e17bce94ee2641512d1537cd992afbb6c019 --- /dev/null +++ b/pharos_dto/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1eb981db6cb84372c7c5f98d5cb72c547e95218abc5ecba8b3e71b377af82543 +size 139435 diff --git a/pharos_dto/basic/plot_14.png b/pharos_dto/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..a283bc9b2864aec7aa5374d4eed9d5cf3b4ea35f --- /dev/null +++ b/pharos_dto/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c3bd81b665f8d754d4a649d109463e14f654dea3ca28a8a9d120956edd670895 +size 140568 diff --git a/pharos_dto/basic/plot_15.png b/pharos_dto/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..94f713a1b038fce582ef522a3e0902f1b1f2ee04 --- /dev/null +++ b/pharos_dto/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1e7d09e32e8c72b4722f4f1843bc5c5c3cad1ae5b8559236119d53f454f0b2bd +size 136604 diff --git a/pharos_dto/basic/plot_16.png b/pharos_dto/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..8c1e880d0be57c5f203e33fd1c1a14b4b5735f66 --- /dev/null +++ b/pharos_dto/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eb014aa3c4fbb7fd67b5fcb45cc016e8a30cde5afe483364a404f7a9ef4a1711 +size 133174 diff --git a/pharos_dto/basic/plot_17.png b/pharos_dto/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..324da885a581f9a98d3e94e7e370b10d72569d39 --- /dev/null +++ b/pharos_dto/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8a12231b67f3317ae56d515053e50f34282ea8e8bf330e3862a73eec741a0627 +size 136981 diff --git a/pharos_dto/basic/plot_18.png b/pharos_dto/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..05807096ac5a30752d478e1639b883002712c6a4 --- /dev/null +++ b/pharos_dto/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8a53ba8fbf0d406248073b43999945e9d66755f53ff18495eb3cdbe1cbedfef7 +size 137136 diff --git a/pharos_dto/basic/plot_19.png b/pharos_dto/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..2421e6547bd27d84a83340923897a50ea551fc0c --- /dev/null +++ b/pharos_dto/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:535d817728e424f17489c418d87310d3122ab0167c6ab901b99e5f05f6eb1824 +size 149883 diff --git a/pharos_dto/basic/plot_2.png b/pharos_dto/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..c60d4c1abfd2254d20e4f3dcef9a047e98ebeb5b --- /dev/null +++ b/pharos_dto/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a63d570114808c6cebfe7e860237b44be82d6912124a4fb942fcff9fe67d9b24 +size 149429 diff --git a/pharos_dto/basic/plot_20.png b/pharos_dto/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..cd664cf4244019492d040bf0b8e160e7c3e436c6 --- /dev/null +++ b/pharos_dto/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0395390cc19d18c63c0be84a28c11f796996bb63535123e07be7475b1971c1f8 +size 150566 diff --git a/pharos_dto/basic/plot_21.png b/pharos_dto/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..8b7a86121471527f36766580ac75c47639c35d69 --- /dev/null +++ b/pharos_dto/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:68b225f2499e9ff3b742cf9ab53c3d90a4f92457b21a57d3b6c69298ad8a74ba +size 144092 diff --git a/pharos_dto/basic/plot_22.png b/pharos_dto/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..336997951f7e0d69033e630c4f3caa556320951c --- /dev/null +++ b/pharos_dto/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:082b9fd642282a56801ff49225db32de5f8467727ea97cd8a0dc6c2e0efd6113 +size 142912 diff --git a/pharos_dto/basic/plot_23.png b/pharos_dto/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..ed5d876c1fb9984b10fbb1cb3aaa303f01652c62 --- /dev/null +++ b/pharos_dto/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1a480f2546e96d82594a8502f574abac8c3ec517012971cd11028faa47108d0c +size 144303 diff --git a/pharos_dto/basic/plot_3.png b/pharos_dto/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..adceb2b31676c12fc2d2cb6286e657c43b3e874d --- /dev/null +++ b/pharos_dto/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fb1e8e9c73373daabac5013a1ee895ee0258c097aafa4111c8c8648da4e04ed0 +size 130089 diff --git a/pharos_dto/basic/plot_4.png b/pharos_dto/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..1d65f56d7b8078bbf72b50e2064ee447eeca49d6 --- /dev/null +++ b/pharos_dto/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e065e1863fd26895d8abf1f5a3428836e16aea874df307f120cb71104541f879 +size 139910 diff --git a/pharos_dto/basic/plot_5.png b/pharos_dto/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..fccae0e0f1d76c056390bd5bdbcc1810974cc533 --- /dev/null +++ b/pharos_dto/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4a8a5221e070b812b3f7218cfecf35c56f7b9fb0708201039846e6b11846f6dc +size 130752 diff --git a/pharos_dto/basic/plot_6.png b/pharos_dto/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..17be87e83b9a6ebfb495b547e4a496195da9a296 --- /dev/null +++ b/pharos_dto/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:14cde36af4b01d6efa1b155f3fb9852d81257b3ace45bb3d4ff5f1f1f8c0ec2e +size 136781 diff --git a/pharos_dto/basic/plot_7.png b/pharos_dto/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..709e2e3187a75ef656b2835bb687783dbd53f46c --- /dev/null +++ b/pharos_dto/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e15af817724ed476d6927c727eaadadf33b9cf8f6996dcc8939ccc11decf1395 +size 145031 diff --git a/pharos_dto/basic/plot_8.png b/pharos_dto/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..28efc50632f0e68ad1e2d1bbc556042814150e95 --- /dev/null +++ b/pharos_dto/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:41310e72dd8452e37a370c0a07c7264d400cf647a8d4309c1f68b05ced413db3 +size 139718 diff --git a/pharos_dto/basic/plot_9.png b/pharos_dto/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..29cb8570a8204ce4960e7317ed4a5a1e28f753e0 --- /dev/null +++ b/pharos_dto/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6f422cbc773d01520db07f409fdd17c1b8fbef46c9a71269813b654cb83f0bec +size 133042 diff --git a/pharos_dto/consensus.joblib b/pharos_dto/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..01f33fa08c7a533bef18b4402e067e6b9132158c --- /dev/null +++ b/pharos_dto/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5427e09331d996741cb411d92dd94611563cab1b8f347ec1307b749c62b956b3 +size 695254 diff --git a/pharos_dto/df_merge.tsv b/pharos_dto/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1fb52816e739a883174bc71417563537b1fa73fb --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,13 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transporter 74 182 5.262514030810373 1.420988160332582e-07 57.59466019417476 188.27912621359224 1.4971900036635353 0.4160578104205245 21.77919356765414 18.57070590158326 1.926868489654782 0.421013047757716 2.6047647441368013e-08 0.0005302437982376 0.0002746260795017 9.217777819724113e-08 9.234745734600398e-07 +SLC superfamily of solute carriers 29 41 4.540008159271654 5.625205137027578e-06 18.888349514563107 44.33009708737864 2.1618907004737498 0.1690913715307362 9.633686860107934 5.825351940723624 1.7350998035598977 0.2760301582542676 0.0017759893628004 0.001896606008153 0.002039237669502 0.001676928362445 0.0005376191014809 +SLC25 family of mitochondrial transporters 17 20 3.4572099384186736 0.0005457994656994 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 5.74392051277431e-07 2.999850516257853e-05 2.788863476938184e-05 1.830839127146827e-07 9.354980213840477e-08 +Calmodulin 6 16 2.480706759546614 0.0131122193810446 5.330097087378641 14.50728155339806 1.3338669185027796 0.2094989649985028 2.1356354617596836 1.8597539737980884 1.176586593960994 0.2465515447823433 0.0116058691176623 0.1457663642848915 0.0390334649397651 0.0072943082509093 0.0007191550657462 +Intracellular calcium-sensing protein 6 16 2.480706759546614 0.0131122193810446 5.330097087378641 14.50728155339806 1.3338669185027796 0.2094989649985028 2.1356354617596836 1.8597539737980884 1.176586593960994 0.2465515447823433 0.0116058691176623 0.1457663642848915 0.0390334649397651 0.0072943082509093 0.0007191550657462 +Receptor 8 33 2.42217317999907 0.0154279962194552 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.0288645441350534 1.0 0.2789376381858768 0.014982846631896 0.0726847885070081 +Calcium-binding protein 7 21 2.420389729239563 0.015503880742113 6.135922330097087 18.021844660194176 1.3650952896045327 0.2072953623045914 2.3371152398743247 2.2037057261181348 1.237653756718734 0.2545563939054063 0.0088508430941383 0.0212633176973237 0.0102417527095019 0.0050545837055134 0.0015084049643282 +Mitochondrial nucleotide transporter subfamily 6 8 2.338936814884357 0.0193387038206689 4.216019417475728 9.065533980582524 1.5870110662923598 0.1668197633609344 2.720728714423222 1.1029864386277723 1.1616247375257451 0.2431804664231326 0.0006394246968973 0.0023758658868836 0.0003823532959252 0.0003832983840783 0.0005338561483377 +Glycosyltransferase 11 16 2.3276184532321924 0.0199323726995677 5.713592233009709 16.264563106796118 0.58827010515732 0.444796659838118 2.8207810163966904 2.842193627279741 1.1276277753027448 0.3350616775048655 0.257801411809195 0.2670314735990955 0.4635835476922714 0.199027105147879 0.0325410063420203 +Signaling 6 20 2.2178694478261383 0.0265637352039955 5.66747572815534 18.009708737864077 1.330299096012152 0.2668377480945127 2.507969905227609 1.6994867622232877 1.0107551340834326 0.2926688105318188 0.036407424611855 0.3523884632837075 0.2135556743224783 0.0204881179470985 0.1359088323682695 +Extracellular structure 2 8 2.10812370168169 0.0350202907656651 2.842233009708738 8.092233009708737 0.8560017356043709 0.3472532488838395 1.4285109580808126 1.0866524100509705 0.962827743376652 0.290186194394739 0.0349575779036428 0.1201219647894398 0.0265618978442646 0.0247234076565489 0.1303826157459173 +Atypical group 6 9 2.103693406743924 0.0354051999706472 2.128640776699029 5.014563106796117 0.0814264921313593 0.5488402806206053 1.4732089989046924 1.745947194287626 0.8980631823569926 0.2901692172933006 1.0 1.0 1.0 1.0 0.0010145405611514 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6ed0718b3af576e79b8a45085eb948b3465d264c --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 2122, + "title": "Average number of proteins per term", + "value": 3.1366635249764374 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..9b2d2643b8e1fad67fa6de10708f3d75e90bea59 --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..a07cfd6c97ee462e5d8eb85ad8428e32046fb914 --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,79 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transporter 0.4989852893511187 5.262514030810373 1.420988160332582e-07 0.0003014882523286 0.0003015336876246 182 Q9BQE5,P20020,Q9P2W9,O14678,P24390,P24539,P11279,O00560,Q9UBX3,P16615,Q70HW3,Q9Y6C9,P53985,P30825,O95202,Q9H0U3,Q96NB2,Q9Y6M7,Q9BQT8,Q13190,P08183,P12236,Q12768,Q96ES6,P11166,Q7Z3B4,Q99567,P06576,O14975,Q9Y619,Q9H2V7,Q9Y487,O95249,Q9H2D1,P28288,P49257,Q9UJS0,Q15070,Q9UPT5,Q8TB61,Q9BSK2,Q15043,Q6NUK1,O75746,P17900,P51572,P55011,O43808,O60684,Q9NZJ7,Q92973,Q9Y3B3,Q9C0E2,Q9BXP2,Q99523,Q03519,Q00325,P12235,O43772,Q9HD45,Q03518,Q8N1F7,Q93050,Q92544,O43731,Q12769,Q13277,P05023,Q8NFH4,P13473,P52294,Q9Y584,O95487,Q9NUT2 74 +SLC superfamily of solute carriers 0.6983487499309804 4.540008159271654 5.625205137027578e-06 0.0118657588691537 0.0023421912933204 41 Q9UBX3,Q70HW3,Q9Y6C9,P53985,P30825,O95202,Q9H0U3,Q96NB2,Q9Y6M7,Q9BQT8,P12236,P11166,O14975,Q9Y619,Q9H2V7,Q9H2D1,Q9UJS0,Q8TB61,Q9BSK2,Q15043,Q6NUK1,O75746,P55011,O43808,Q9NZJ7,Q9BXP2,Q00325,O43772,P12235 29 +SLC25 family of mitochondrial transporters 0.7736349387963399 3.4572099384186736 0.0005457994656994 0.6860440689962588 0.0029359788928659 20 Q6NUK1,O75746,P12236,Q02978,O43808,Q9UBX3,Q9Y619,Q9NZJ7,Q70HW3,Q9Y6C9,Q9H2D1,Q9UJS0,Q9BSK2,Q00325,O43772,Q9BQT8,P12235 17 +Miscellaneous SLC25 mitochondrial transporters 0.9028588098016276 2.9789438723851127 0.002892437559238 0.9978593509197236 0.0079504566071284 2 Q9Y6C9 1 +SLC12 family of cation-coupled chloride transporters 0.8264294049008157 2.624007182157026 0.0086901952624562 0.9999999909562124 0.017731340718204 2 P55011 1 +RSK subfamily 0.8159276546091014 2.574084676755129 0.0100505672205344 0.9999999995093072 0.0198657970332001 2 Q15418 1 +RSK family 0.8159276546091014 2.574084676755129 0.0100505672205344 0.9999999995093072 0.0198657970332001 2 Q15418 1 +Calmodulin 0.6834071866934295 2.480706759546614 0.0131122193810446 0.9999999999993142 0.0243857401635204 16 O43852,P80303,Q14257,Q9BRK5,Q02818,P41208 6 +Intracellular calcium-sensing protein 0.6834071866934295 2.480706759546614 0.0131122193810446 0.9999999999993142 0.0243857401635204 16 O43852,P80303,Q14257,Q9BRK5,Q02818,P41208 6 +Receptor 0.5116367706905744 2.42217317999907 0.0154279962194552 0.9999999999999952 0.027580630141267 33 Q8WTV0,Q9BUN8,P57105,Q9UQB8,Q567V2,Q9NR77,Q14108,A6NIH7 8 +Calcium-binding protein 0.6066279306055954 2.420389729239563 0.015503880742113 0.999999999999996 0.0276696677331908 21 P43307,P80303,O43852,Q14257,Q9BRK5,Q02818,P41208 7 +AUR family 0.7750875145857692 2.377251980442686 0.0174421683836634 1.0 0.0303433624633544 2 O14965 1 +Mitochondrial nucleotide transporter subfamily 0.78794541510067 2.3389368148843572 0.0193387038206689 1.0 0.0325430051605547 8 Q6NUK1,P12236,Q70HW3,Q9H2D1,P12235,Q9BSK2 6 +Glycosyltransferase 0.6584686512001219 2.3276184532321924 0.0199323726995677 1.0 0.0333831845844378 16 P46976,O60762,Q10472,Q8N4A0,Q9BT22,P04844,Q8TCJ2,P46977,O60512,Q8NAT1,P04843 11 +Signaling 0.5847808436476434 2.2178694478261383 0.0265637352039955 1.0 0.0420031640110869 20 Q96PC5,Q8WUJ1,O15173,P43490,O00264,Q96GC9 6 +SLC56 Sideroflexins 0.7289964994165585 2.1499877326191488 0.0315561851458232 1.0 0.0482089451975788 2 Q96NB2 1 +Extracellular structure 0.7418252168358053 2.10812370168169 0.0350202907656651 1.0 0.0524439357831626 8 O75718,Q32P28 2 +Atypical group 0.7270780129764723 2.1036934067439237 0.0354051999706472 1.0 0.0528752931685326 9 P42345,Q15120,Q15118,Q13315,Q13535,P78527 6 +Aspartic protease 0.7843673237307484 2.043645769124128 0.0409885542720855 1.0 0.0594516146038042 3 Q8TCT9 1 +PDHK family 0.7624744674642364 1.9429114017248337 0.0520268640837113 1.0 0.0720163115366181 3 Q15118,Q15120 2 +Oxidase 0.5396503296481565 1.940511873211568 0.0523175126364221 1.0 0.0722990591308003 21 P14406,O15260,Q6ZRP7,Q709F0,O43169,O75845,Q15800,O15254,Q15067 9 +Ca2+-ATPases 0.758097461336428 1.9226613667524608 0.0545225916697686 1.0 0.0747435679793221 3 P20020,P16615 2 +BUB family 0.6753208868144622 1.8787250469407144 0.0602820459811914 1.0 0.0806039707448571 2 O43683 1 +Oxygenase 0.8032563183111248 1.8741181011970225 0.0609141489478699 1.0 0.0812443897343683 5 Q14534 1 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.8106380859885816 1.824439033507784 0.0680857254091393 1.0 0.0887677636636252 4 Q9UBX3 1 +SNARE protein 0.6843950905903001 1.813435309702504 0.0697647076823837 1.0 0.0903789436520258 8 Q86Y82,Q13190,Q9P2W9,Q13277,O95249,Q9UNK0,P51809 7 +Phospholipase 0.7880640528959638 1.8072521083587096 0.0707229795610144 1.0 0.0915086357490687 5 Q8NCC3 1 +PIKK family 0.7997664915353041 1.7778775680064751 0.0754239651696235 1.0 0.0963574076399405 4 Q13315,P42345,Q13535 3 +Membrane trafficking regulatory protein 0.5230841167888678 1.7762698264042194 0.0756884540364015 1.0 0.0965790135088659 20 O43731,P13473,P24390 3 +Mitochondrial amino acid transporter subfamily 0.7799495207543852 1.7713913313736258 0.0764956491136965 1.0 0.0972580991128005 5 O43772,Q9UJS0,Q9Y619 3 +ATP-binding cassette transporter family 0.7176586116900832 1.763755603377258 0.0777731351477113 1.0 0.0982933846238495 7 P08183,P28288,Q03519,Q03518,Q9NUT2 5 +Metalloprotease 0.4133473362415606 1.7040437195381914 0.0883729197762095 1.0 0.1088376876175952 38 O75844,Q99797,Q10713,P42892,Q9UIQ6,O95630,Q5JRX3,Q6P179,Q9NZ08,Q9BYT8 10 +Lipase 0.7374363397655989 1.6631687391662318 0.0962786632940511 1.0 0.1167447562914151 6 Q8NCC3 1 +P-type ATPases 0.7523006746101393 1.6484921513357378 0.0992517199703926 1.0 0.1196659941915756 5 P20020,P05023,P16615 3 +Phosphatase inhibitor 0.6722510699170174 1.540898479283067 0.1233414960157195 1.0 0.1419363636363106 7 P55209 1 +ABCB subfamily 0.7107579731779397 1.5399035627562794 0.1235838622367162 1.0 0.1421381873530145 6 P08183,Q03518,Q03519,Q9NUT2 4 +Protease 0.3194998739705919 1.5314495683802631 0.125658321392984 1.0 0.1441334908086011 116 P61978,Q9UIQ6,Q6P179,Q9H4L4,O75844,Q8TCT9,O14773,Q99797,Q10713,Q9HB40,Q5BJF2,P67812,Q8NHP8,Q9NZ08,Q2T9J0,P42892,Q9H3G5,P42785,Q5JRX3,Q96AE4,Q9BYT8,P10619,Q13510,Q96K76 24 +Extracellular matrix glycoprotein 0.7371382604232006 1.5067054203358938 0.1318861815871521 1.0 0.1494991866068038 4 Q32P28 1 +SET domain 0.7224936491495414 1.4427163330003971 0.1491003963202812 1.0 0.1653035741858081 4 Q9H7B4 1 +Serine protease 0.4222248210825896 1.4217248015479722 0.1551061572495964 1.0 0.1704480920163871 29 Q2T9J0,O14773,P61978,P10619,Q9HB40,Q9H3G5,P67812,P42785,Q92945,Q96AE4 10 +Tubulin 0.6703081321686463 1.3516252116618372 0.1764952408684323 1.0 0.1893072284548454 6 P04350,P07437,Q13885,P68371 4 +Hsp90 family chaperone 0.6776489007317615 1.3125148002022693 0.189346495665291 1.0 0.2001959460895603 5 Q58FF6,P14625,P07900 3 +Growth factor 0.6512162749688306 1.1928946781846188 0.2329106237268479 1.0 0.2445503926513464 5 Q96PC5 1 +Protein methyltransferase 0.5461562311109454 1.1305611313118866 0.2582398549186935 1.0 0.2704762942435674 9 Q9H7B4,O96028 2 +CDK1 subfamily 0.5277129521587088 1.1071815298274303 0.2682154514828292 1.0 0.2807859832494147 2 P24941 1 +Kinase activator 0.6401055795783022 1.0815598636939543 0.2794481470076375 1.0 0.2922567609414523 4 O95067,Q16543 2 +Writer 0.5276451592321946 1.0807220966578903 0.2798207508627737 1.0 0.2925022824289683 10 Q9H7B4,O96028 2 +CAMK2 family 0.5075845974329138 1.0017887194662571 0.3164456465616041 1.0 0.3302988991656291 2 Q13555 1 +Oxidoreductase 0.2879491702209834 1.0004257516144353 0.3171045128703798 1.0 0.3308238821587738 118 P51970,P05091,Q96CU9,O43169,Q8N0U8,O95168,Q13423,Q16134,Q15392,P00403,Q9P0J0,O15254,O95831,O75306,Q6ZRP7,O95881,Q15067,P14406,Q9Y6M9,P03886,Q9UDW1,Q709F0,P00374,Q16850,O75845,Q9H7Z7,Q15800,P23378,Q14739,O15260,Q8N4Q0,Q14534,O76062 33 +Esterase 0.5026401392463049 0.9932263171709218 0.3205996759508229 1.0 0.3343059028833642 11 Q969T7,O14734,P50897 3 +Phosphatase modulator 0.4934196863468769 0.8449929349778587 0.3981147836737664 1.0 0.4135093347800941 9 P55209 1 +Reductase 0.4191614041722302 0.8301473033574867 0.4064555050547378 1.0 0.4215535590059401 17 Q9H7Z7,Q9UDW1,P00374,O95168,O95881,Q15392,Q14739,O76062 8 +Methyl-lysine/arginine binding protein 0.5478888320252422 0.7852323449630233 0.4323173544667293 1.0 0.4476621514072562 6 Q9UHJ3 1 +Acetyltransferase 0.3823199180742346 0.7818896312229324 0.4342794391672742 1.0 0.4493130033705294 22 P23786,Q96N66,O14929 3 +Translation initiation factor 0.3834723353687019 0.7642445218595421 0.4447215393602088 1.0 0.4592209764099091 21 P55010,O75153 2 +Cadherin 0.4501166861143728 0.7085873100392981 0.4785806134759198 1.0 0.4934635868784752 2 Q14126 1 +mRNA splicing factor 0.294295259767209 0.6743760395206464 0.5000722719487531 1.0 0.5148730524382602 60 Q92804,P98179,P62995,P23246,O95391,P35637,Q13595,Q96PK6,Q01844,Q9BWF3,Q07666,P38159 12 +Chromodomain 0.4878902830464123 0.6507632897579997 0.5151993009596247 1.0 0.5301905512300309 3 Q13185,P45973 2 +CDK family 0.4351770258081349 0.5153878187452668 0.6062820428977052 1.0 0.6218127090521655 8 P21127,Q9NYV4 2 +Transaminase 0.4262495038967211 0.5015594575734825 0.6159774440003958 1.0 0.6314512735115169 9 O15269 1 +Epigenetic regulator 0.3078000512968289 0.4896703150090794 0.6243672109316343 1.0 0.6394339872572046 32 O14744,Q9H7B4,Q9UHJ3,Q9UBN7,O96028,Q8NB78,Q16637 7 +Nucleotide phosphatase 0.4540036771980094 0.486049366607429 0.6269321650730446 1.0 0.6417511115701885 7 P49902,Q9H857,O43681 3 +Lyase 0.3486842875518452 0.4806504945289248 0.6307649213399977 1.0 0.6453631451704316 19 A1L0T0,O96005,Q96KA5,P53701 4 +PKC alpha subfamily 0.3792298716452734 0.3838298575645413 0.7011045568312535 1.0 0.7159498891221944 2 P05771 1 +DNA helicase 0.3821408221843915 0.3798324188043431 0.7040698159337757 1.0 0.7186321064990245 12 Q14566,P46063,P28370 3 +Translation factor 0.3099999361347869 0.3709987954916013 0.7106384288531447 1.0 0.7249878586665254 27 P55010,O75153 2 +Transferase 0.2478801270456533 0.3518450976495658 0.7249544352855515 1.0 0.739237535644373 141 Q6UX53,O60512,Q9NZW5,P21964,P23786,O15269,O15270,Q8N4A0,Q9BWD1,P46977,Q96N66,Q14168,P40937,O15127,Q10472,P34896,P30876,P52429,O00411,O60762,P48651,Q8NF37,Q9BT22,P04844,Q8TCJ2,Q13126,Q8NAT1,O14929,P35610 29 +Ion channel 0.3849785530095391 0.2965376590018478 0.7668195117565784 1.0 0.780801825310681 8 Q9C0H2 1 +F-type and V-type ATPases 0.3419683124389172 0.2728400767463622 0.7849761510961164 1.0 0.7985231987660398 15 P24539,Q9Y487 2 +V-type ATPase 0.3771956299856737 0.2663100549429777 0.7900004299095575 1.0 0.8031233123570599 8 Q9Y487 1 +Hydrolase 0.2424687901140434 0.236468895408352 0.8130688407968121 1.0 0.8247285278063267 108 Q5T9A4,O14734,P30154,P06865,P50897,P49902,P32321,Q8N2A8,P16278,P10253,Q9NVI7,Q86YN1,P15586,Q99519,Q9Y570,Q8NCC3,O43865,Q9NPH0,Q969T7,Q9H857,P11117,Q08431,Q16537,Q14738 24 +Ubiquitin-protein ligase 0.3091593197620663 0.2021200741770607 0.8398228548036215 1.0 0.8510525777904894 18 P46934 1 +Immune response 0.3896953190144986 0.1792820134707514 0.8577162692090325 1.0 0.8679417850555875 6 Q9NX40 1 +F-type ATPase 0.3669836350669428 0.1651178035889659 0.8688512601122726 1.0 0.8787904546988764 7 P06576,P24539 2 +G-protein 0.2520910327184875 0.051109710482787 0.9592380982610802 1.0 0.9660670358376896 31 O15397,O60313,P61586,Q9NTK5 4 +Guanyl-nucleotide exchange factor 0.3356039513297134 0.0497997536143561 0.9602819630284024 1.0 0.966659547223088 4 Q96N67,Q9Y4G8 2 +Helicase 0.2546255506607737 0.0036059681479825 0.9971228599232242 1.0 1.0 25 P46063,O43143,Q9BQ75,Q96RR1,Q6P158,O60264,P33993,Q9H4L7,Q14566,P13010,Q7Z478,Q14562,Q92620,P12956,Q92900,Q8IX18,P33991,P42694,Q9UL03,P49736,Q08211,P28370,P25205,Q8IY37 24 +Damaged DNA-binding protein 0.2933450087565743 0.0027645826261957 0.9977941850153051 1.0 1.0 4 P54727,Q9NYH9,P54725 3 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..3747afd04fb844ace4f538d93223d73b6a0de595 --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1,4-alpha-glucan-branching enzyme", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "2-oxoisovalerate dehydrogenase subunit beta, mitochondrial", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-aminobutyrate aminotransferase, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AMP deaminase 2", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family B member 8, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family D member 4", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "ATR subfamily", "AUR family", "Abl interactor 1", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 1A", "Actin-related protein 2/3 complex subunit 1B", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Acyl-CoA dehydrogenase family member 11", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylate kinase isoenzyme 6", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Adenylyltransferase and sulfurtransferase MOCS3", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase family 16 member A1", "Aldehyde dehydrogenase, mitochondrial", "Aldolase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amylase", "Amyloid-beta A4 protein", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Ankyrin repeat and SAM domain-containing protein 1A", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Antigen peptide transporter 2", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis regulator BAX", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Arsenite methyltransferase", "Arylsulfatase A", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atlastin-3", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical group", "Aurora kinase a", "Aurora kinase b", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BUB family", "BUB3-interacting and GLEBS motif-containing protein ZNF207", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Bcl-2-associated transcription factor 1", "Beclin-1", "Beta-1,4-galactosyltransferase 3", "Beta-adducin", "Beta-arrestin-2", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biogenesis of lysosome-related organelles complex 1 subunit 1", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, cytosolic", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breakpoint cluster region protein", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CAP-Gly domain-containing linker protein 1", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 3", "CCR4-NOT transcription complex subunit 4", "CCR4-NOT transcription complex subunit 7", "CD2 antigen cytoplasmic tail-binding protein 2", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CHK1 subfamily", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CLK family", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CRK7 subfamily", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-regulated heat-stable protein 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit delta", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calponin-2", "Calponin-3", "Calreticulin", "Calsyntenin-3", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Caspase-3", "Caspase-7", "Cat eye syndrome critical region protein 2", "Catechol O-methyltransferase", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division cycle and apoptosis regulator protein 1", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Centrosome-associated protein CEP250", "Chaperone", "Chaperonin", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Chromatin accessibility complex protein 1", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "Citron rho-interacting kinase", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Coronin-7", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4A", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 12", "Cyclin-dependent kinase 13", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytokine receptor", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic carboxypeptidase 1", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DDB1- and CUL4-associated factor 13", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA damage-binding protein 1", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA primase small subunit", "DNA replication complex GINS protein PSF1", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-binding protein SATB2", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC2", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase III subunit RPC5", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(14)-sterol reductase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidylate deaminase", "Deoxyribose-phosphate aldolase", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Derlin-2", "Desmocollin-2", "Desmoglein-2", "Desmoplakin", "Diacylglycerol kinase epsilon", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 3", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Dna-dependent protein kinase catalytic subunit", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity mitogen-activated protein kinase kinase 2", "Dual specificity protein kinase clk3", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase CBL", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase NEDD4", "E3 ubiquitin-protein ligase NEDD4-like", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D2", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER lumen protein-retaining receptor 3", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "ETS-related transcription factor Elf-2", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Endodeoxyribonuclease", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Esterase", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6B", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Flap endonuclease 1", "Forkhead box protein C1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "G2/mitotic-specific cyclin-B1", "G2/mitotic-specific cyclin-B2", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GDP-mannose 4,6 dehydratase", "GEK subfamily", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General transcription factor IIH subunit 1", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate dehydrogenase 1, mitochondrial", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamine-rich protein 1", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate dehydrogenase 1-like protein", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogenin-1", "Glycosidase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5", "Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "HBS1-like protein", "HDAC class I", "HDAC class III", "HDAC class IIb", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase 6", "Histone deacetylase complex subunit SAP18", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EHMT1", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase SETD2", "Histone-lysine N-methyltransferase SETD7", "Histone-lysine N-methyltransferase SMYD3", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Huntingtin-interacting protein 1-related protein", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "IRAK family", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin receptor superfamily", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-3", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive serine/threonine-protein kinase vrk3", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inhibitor of nuclear factor kappa-b kinase subunit beta", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrator complex subunit 6", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Interleukin-1 receptor-associated kinase 1", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isoaspartyl peptidase/L-asparaginase", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF1A", "Kinesin-like protein KIF1B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIFC1", "Kinetochore protein NDC80 homolog", "Kinetochore protein Nuf2", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lactadherin", "Lambda repressor-like transcription factor", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat flightless-interacting protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Leukocyte elastase inhibitor", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysophospholipid acyltransferase LPCAT4", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "M-phase inducer phosphatase 3", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAPK family", "MAPKAPK family", "MAPKAPK subfamily", "MARK subfamily", "MAST family", "MBT domain", "MCU family", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MSN subfamily", "MST subfamily", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Map kinase-activated protein kinase 3", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D1", "Melanoma-associated antigen D2", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Methyltransferase-like protein 7B", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial glutamate carrier 1", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-1", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase kinase kinase 7", "Mitogen-activated protein kinase kinase kinase kinase 4", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multifunctional protein ADE2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "Myotubularin-related protein 2", "Myotubularin-related protein 6", "N-acetyl-D-glucosamine kinase", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 25, NatB auxiliary subunit", "N-alpha-acetyltransferase 35, NatC auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal kinase-like protein", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NAD-dependent protein deacetylase sirtuin-2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD4-like E3 ubiquitin-protein ligase WWP2", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurofibromin", "Neurolysin, mitochondrial", "Neuropathy target esterase", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear cap-binding protein subunit 2", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor coactivator 5", "Nuclear receptor corepressor 1", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin p54", "Nucleoside diphosphate kinase 3", "Nucleoside diphosphate kinase A", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "OTU domain-containing protein 7B", "Obg-like ATPase 1", "Occludin", "Opioid growth factor receptor", "Origin recognition complex subunit 3", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PAX3- and PAX7-binding protein 1", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 3", "PDZ and LIM domain protein 5", "PEK family", "PH-interacting protein", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PITSLRE subfamily", "PKA family", "PKC alpha subfamily", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidase M20 domain-containing protein 2", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal bifunctional enzyme", "Peroxisomal biogenesis factor 19", "Peroxisomal carnitine O-octanoyltransferase", "Peroxisomal leader peptide-processing protease", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Persulfide dioxygenase ETHE1, mitochondrial", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 3-kinase regulatory subunit beta", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylated adapter RNA export protein", "Pirin", "Plakophilin-2", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polyadenylate-binding protein-interacting protein 1", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polyhomeotic-like protein 2", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polypeptide N-acetylgalactosaminyltransferase 4", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 17", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor 18", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SLU7", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable cysteine--tRNA ligase, mitochondrial", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable helicase with zinc finger domain", "Probable histidine--tRNA ligase, mitochondrial", "Probable leucine--tRNA ligase, mitochondrial", "Probable proline--tRNA ligase, mitochondrial", "Probable serine carboxypeptidase CPVL", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein Hook homolog 1", "Protein LSM14 homolog B", "Protein NDRG1", "Protein NDRG3", "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2B", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein S100-A13", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SET", "Protein XRP2", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase subunit beta", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c alpha type", "Protein kinase c beta type", "Protein kinase c delta type", "Protein lin-28 homolog B", "Protein lin-9 homolog", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein strawberry notch homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec24D", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Proto-oncogene c-Rel", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Pumilio homolog 1", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative heat shock protein HSP 90-beta 4", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal phosphate phosphatase", "Pyridoxine-5'-phosphate oxidase", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RAF family", "RIO family", "RIO1 subfamily", "RIO2 subfamily", "RIPK family", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding protein", "RNA helicase", "RNA polymerase II subunit A C-terminal domain phosphatase", "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein 7", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab proteins geranylgeranyltransferase component A 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rac GTPase-activating protein 1", "Radixin", "Raf proto-oncogene serine/threonine-protein kinase", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein nGAP", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras GTPase-activating-like protein IQGAP3", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein R-Ras2", "Ras-related protein Ral-A", "Reader", "Receptor", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Rel homology transcription factor", "Remodeling and spacing factor 1", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinoblastoma-associated protein", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Rho GDP-dissociation inhibitor 1", "Rho GTPase-activating protein 18", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribose-phosphate pyrophosphokinase 2", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 2 homolog", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "S1 RNA-binding domain-containing protein 1", "SAP30-binding protein", "SCY1 family", "SEC23-interacting protein", "SET domain", "SGK family", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC35 family of nucleotide sugar transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRC family", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "Sal-like protein 2", "Sarcolemmal membrane-associated protein", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Scm-like with four MBT domains protein 1", "Scy1-like protein 2", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Selenide, water dikinase 1", "Sentrin-specific protease 3", "Separin", "Septin-11", "Septin-2", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine-protein kinase atm", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase atr", "Serine/threonine-protein kinase chk1", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase greatwall", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase rio1", "Serine/threonine-protein kinase rio2", "Serine/threonine-protein kinase sgk3", "Serine/threonine-protein kinase tao1", "Serine/threonine-protein kinase ulk3", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "Serpin B6", "Serpin H1", "Set1/Ash2 histone methyltransferase complex subunit ASH2", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sialidase-1", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal recognition particle 14 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signal-induced proliferation-associated protein 1", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium-dependent HCO3- transporters", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 9", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 35 member F2", "Something about silencing protein 10", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-14", "Sorting nexin-2", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Splicing regulatory glutamine/lysine-rich protein 1", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Srsf protein kinase 2", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptojanin-2-binding protein", "Syntaxin-12", "Syntaxin-18", "Syntaxin-3", "Syntaxin-5", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 3", "Syntenin-1", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "T-complex protein 11-like protein 1", "TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L", "TAK1 subfamily", "TAO subfamily", "TATA-binding protein-associated factor 2N", "TBC1 domain family member 10B", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TNF receptor-associated factor 2", "TOPK family", "TP53-binding protein 1", "TRIO family", "TTK family", "Tapasin", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tetratricopeptide repeat protein 28", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Thiosulfate sulfurtransferase", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid adenoma-associated protein", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Torsin-1A", "Trafficking protein particle complex subunit 4", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription factor 20", "Transcription factor SPT20 homolog", "Transcription factor p65", "Transcription initiation factor IIB", "Transcription initiation factor IIE subunit beta", "Transcription initiation factor TFIID subunit 6", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-beta", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transforming protein RhoA", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-2", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Triple functional domain protein", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "Tyrosine-protein kinase yes", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "UDP-glucose:glycoprotein glucosyltransferase 1", "ULK family", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog A", "UV excision repair protein RAD23 homolog B", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 34", "Ubiquitin carboxyl-terminal hydrolase 4", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-Ie", "Unconventional myosin-VI", "Unconventional myosin-Va", "Upstream-binding protein 1", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuolar protein sorting-associated protein 72 homolog", "Vacuole membrane protein 1", "Very long-chain acyl-CoA synthetase", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "WNK family", "Winged helix/forkhead transcription factor", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YLP motif-containing protein 1", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCCH domain-containing protein 7A", "Zinc finger CCCH domain-containing protein 7B", "Zinc finger CCHC domain-containing protein 8", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 3", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein ubi-d4", "Zinc finger transcription factor", "Zinc transporter ZIP14", "Zyxin", "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-decapping enzyme 1A", "mRNA-decapping enzyme 1B", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "tRNA pseudouridine synthase A"], "available_proteins": ["AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD6", "ABI1", "ACAA1", "ACAA2", "ACAD11", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGTPBP1", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALYREF", "AMPD2", "ANAPC1", "ANKS1A", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APEH", "APOL2", "APP", "ARCN1", "ARFIP1", "ARG2", "ARHGAP18", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC1A", "ARPC1B", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASH2L", "ASNA1", "ASNS", "ASRGL1", "ATAD2", "ATAD3A", "ATAD3B", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATM", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GALT3", "BAG6", "BAIAP2", "BAX", "BCAP31", "BCAS2", "BCAT1", "BCAT2", "BCKDHB", "BCKDK", "BCLAF1", "BCR", "BECN1", "BLMH", "BLOC1S1", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRIX1", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CBL", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC25C", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK9", "CDKN2AIP", "CEBPZ", "CECR2", "CEP170", "CEP250", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK1", "CHEK2", "CHERP", "CHM", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHUK", "CIRBP", "CIT", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLIP1", "CLK3", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNP", "COASY", "COIL", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CROT", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERA", "DERL1", "DERL2", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLST", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL3", "DPYSL5", "DSC2", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELF2", "ELMO2", "ELMOD2", "ELOB", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENO2", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERH", "ERO1A", "ERP29", "ESD", "ESPL1", "ETF1", "ETFA", "ETFB", "ETFDH", "ETHE1", "EWSR1", "EXO1", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZR", "FAHD1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GAK", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBE1", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GID8", "GINS1", "GINS2", "GLB1", "GLDC", "GLRX3", "GLRX5", "GLS", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GPATCH4", "GPD1L", "GPD2", "GPI", "GPKOW", "GPR107", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2H1", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HARS2", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDGFL2", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HELZ", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK1", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90AB4P", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INTS11", "INTS6", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KCTD12", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LNPEP", "LONP1", "LPCAT1", "LPCAT4", "LRRC47", "LRRFIP1", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSM7", "LTN1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS2", "MASTL", "MAT2A", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED14", "MED21", "METTL7B", "MFAP1", "MFGE8", "MFN1", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU2", "MIPEP", "MMS19", "MOCS3", "MORF4L1", "MPC2", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL38", "MRPL39", "MRPL44", "MRPL47", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCBP2", "NCL", "NCOA5", "NCOR1", "ND1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA8", "NDUFA9", "NDUFB1", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEDD4", "NEDD4L", "NEK9", "NEU1", "NF1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NME1", "NME3", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP14", "NOP56", "NOP58", "NOP9", "NPEPPS", "NPM1", "NRBP1", "NRDC", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OGFR", "OLA1", "OPA1", "ORC3", "OTUB1", "OTUD7B", "OXA1L", "OXCT1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAIP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARS2", "PATL1", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDXP", "PEBP1", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHC2", "PHF3", "PHF6", "PHGDH", "PHIP", "PI4K2A", "PI4KA", "PICALM", "PIGK", "PIK3C2A", "PIK3R2", "PIK3R4", "PIP4K2C", "PIR", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PM20D2", "PMPCA", "PMPCB", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLD2", "POLDIP3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PPA1", "PPA2", "PPAT", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1CC", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA2", "PRKACA", "PRKAG1", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF18", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2B", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPRF", "PUDP", "PUM1", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RAD23A", "RAD23B", "RAE1", "RAF1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAPGEF2", "RASAL2", "RAVER1", "RB1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBM7", "RBMX", "RCL1", "RCN1", "RCN2", "RDH11", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIOK1", "RIOK2", "RIPK1", "RNASEH2A", "RNH1", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRAS2", "RRM1", "RRM2", "RRP7A", "RRS1", "RSF1", "RSL1D1", "S100A10", "S100A11", "S100A13", "SAE1", "SALL2", "SAP18", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCML2", "SCO1", "SCO2", "SCPEP1", "SCYL1", "SCYL2", "SDCBP", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD2", "SETD7", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFMBT1", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SGK3", "SHMT1", "SHMT2", "SIN3A", "SIPA1", "SIRT1", "SIRT2", "SKP1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLK", "SLMAP", "SLU7", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMN1*", "SMYD3", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX14", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPCS2", "SPCS3", "SPNS1", "SPTLC1", "SPTLC2", "SQLE", "SRBD1", "SREK1", "SRM", "SRP14", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSU72", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK4", "STOML2", "STRBP", "STT3A", "STT3B", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "SUCLA2", "SUCLG2", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNJ2BP", "TAB1", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TAOK1", "TAP1", "TAP2", "TAPBP", "TARS", "TARS2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TCP11L1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM22", "TJP1", "TJP2", "TK1", "TKT", "TM7SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOR1A", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRAPPC4", "TRIO", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TST", "TSTA3", "TTC28", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UBP1", "UCHL5", "UCK2", "UGGT1", "ULK3", "UNC119", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP28", "USP34", "USP39", "USP4", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP3", "UTP6", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VMP1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS72", "VRK1", "VRK2", "VRK3", "WARS", "WASF2", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR4", "WDR74", "WDR82", "WNK1", "WWP2", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YES1", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H7A", "ZC3H7B", "ZCCHC11", "ZCCHC8", "ZFR", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF598", "ZNF622", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB8", "ABCD3", "ABCD4", "ACAD11", "ACAT2", "ACOT8", "ACOX1", "ACOX3", "ACP2", "ACP6", "AHCYL1", "AIFM1", "ALDH2", "ALG1", "APOL2", "ASAH1", "ASNA1", "ATAD3A", "ATAD3B", "ATM", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP5F1", "ATP6V0A1", "ATP6V0A2", "ATR", "AURKA", "B4GALT3", "BAIAP2", "BCAP31", "BUB1", "CALU", "CAMK2G", "CBX3", "CBX5", "CCNB2", "CDC37", "CDK11B", "CDK12", "CDK2", "CETN2", "CLPTM1", "CLPTM1L", "CLUH", "CMSS1", "COMT", "COX2", "COX7A2", "CPT2", "CPVL", "CRTAP", "CTSA", "CYB5B", "CYB5D2", "CYP51A1", "DCTD", "DERL1", "DGKE", "DHCR24", "DHFR", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DOCK7", "DOLPP1", "DPM1", "DSG2", "ECE1", "EIF5", "ERAP1", "ERAP2", "ETFDH", "EWSR1", "EXOC7", "FOXRED1", "FUBP1", "FUS", "GAA", "GALNT1", "GALNT4", "GLB1", "GLDC", "GM2A", "GNS", "GOSR1", "GYG1", "HAT1", "HCCS", "HDAC6", "HELZ", "HEXA", "HM13", "HNRNPK", "HSP90AA1", "HSP90AB4P", "HSP90B1", "ILVBL", "INTS6", "IPO8", "KDELR1", "KDELR3", "KDM1B", "KHDRBS1", "KHSRP", "KPNA1", "KPNA6", "LAMP1", "LAMP2", "LBR", "LETM1", "LMAN1", "LNPEP", "LPCAT1", "MAGT1", "MBOAT7", "MCM2", "MCM3", "MCM4", "MCM6", "MCM7", "METTL7B", "MFGE8", "MFSD3", "MIA2", "MIPEP", "MPP2", "MPP6", "MPV17L2", "MSMO1", "MTAP", "MTCH1", "MTCH2", "MTOR", "NAMPT", "NAP1L1", "ND1", "NDUFA13", "NDUFA8", "NDUFB4", "NDUFB9", "NDUFS2", "NEDD4", "NEU1", "NLN", "NNT", "NSD2", "NT5C2", "NT5C3B", "NT5DC2", "NUCB1", "NUCB2", "NUP160", "NUP37", "NUP54", "NUP88", "NUP93", "OCIAD1", "OLA1", "OPA1", "OXA1L", "P3H1", "PDK1", "PDK3", "PGRMC1", "PGRMC2", "PITRM1", "PLA2G15", "PLBD2", "PLD6", "PMPCA", "POLR2B", "POLRMT", "POMGNT2", "PPME1", "PPP2R1B", "PPP2R5D", "PPP2R5E", "PPT1", "PRCP", "PRKCB", "PRKDC", "PRMT5", "PTDSS1", "PTGES2", "PXMP2", "QSOX2", "RAD23A", "RAD23B", "RAPGEF2", "RBM14", "RBM3", "RBM4", "RBMX", "RCN2", "RECQL", "RFC5", "RHOA", "RPN1", "RPN2", "RPS6KA1", "SC5D", "SCAMP2", "SCARB1", "SCARB2", "SCPEP1", "SDCBP", "SDF4", "SEC11A", "SEC24B", "SENP3", "SFMBT1", "SFPQ", "SFXN2", "SHMT1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A6", "SLC27A2", "SLC2A1", "SLC35B2", "SLC39A14", "SLC4A7", "SLC7A1", "SLU7", "SMARCA1", "SMARCA5", "SMARCAD1", "SMN1*", "SMYD3", "SOAT1", "SORT1", "SPNS1", "SPTLC1", "SPTLC2", "SQLE", "SSR1", "STAMBP", "STT3A", "STT3B", "STX12", "STX18", "STX3", "STX5", "STX8", "SURF4", "SYNJ2BP", "TAF15", "TAP1", "TAP2", "TIMM22", "TM7SF2", "TM9SF3", "TM9SF4", "TMED7", "TMEM97", "TNPO1", "TPP1", "TRA2A", "TRA2B", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TWNK", "TXNDC12", "TYSND1", "UNC119B", "UPF1", "UQCR10", "USP47", "UTP6", "VAMP7", "VKORC1L1", "VMP1", "WASHC5", "XPO4", "XRCC5", "XRCC6", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a0739b7a1518393d576dba30d8ec5942decce175 --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Tclin", "1": "Tdark"} \ No newline at end of file diff --git a/pharos_protein_category/advanced/plot_0.png b/pharos_protein_category/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3fb0d490d4e3fd982b8fb8ef24a07804f9a4c3c4 --- /dev/null +++ b/pharos_protein_category/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f671c99d7e24c1b9a5361c97abc97485d2eb9fee2fada82804be22cc420a8a99 +size 192011 diff --git a/pharos_protein_category/advanced/plot_1.png b/pharos_protein_category/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..5f1c20b3cacc2c34a113802c2828e173f0a87126 --- /dev/null +++ b/pharos_protein_category/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:204d71acd71f42f768ba07ad3a00d6bc88ce448b659b4c36a4d0eba110d816a1 +size 207191 diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..ac30eaa9467c7f62fe87d1e47e3a011e4e57e347 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tclin", "1": "Tdark", "2": "Tchem"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..74d104efc41a4d79540bc45949585c603f87e967 --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c506f615e4ee6330c188f0020299763569ab8230d806845f8f9eedf33eaec9e2 +size 140537 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..3c5348e267d252b5533771111a2d2a643d896766 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b26ccc7eaf3a1b89f6eda845bd3d6ce07713ac881123de4167218258f3a2535c +size 131883 diff --git a/pharos_protein_category/basic/plot_2.png b/pharos_protein_category/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..578d7ffa3d5895a60edc38aaedbdbd460a577fdc --- /dev/null +++ b/pharos_protein_category/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:54588a3f06e0ded61bb58dd8db98a860b07a18ca9a789790b166cf334e4586dc +size 137322 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7dd7280710a633fc8ab1c2c2ab136a825190fee8 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:132f0e2c7211769a2f2ff84a1e9a5b94ea6bca0a45a2ea9c946323723bdd1a20 +size 88093 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..30745d9a07a75b1a58c798df6b5011e5d472f5a1 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1,3 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Tclin 31 87 3.02500654351712 0.0024862774817395 19.366504854368937 86.39077669902913 0.9399778874953114 0.4805096456956057 6.659845213621253 7.009024167820235 0.9745051203556824 0.3806460486794667 0.0200419872552402 0.0919373334690581 0.0639560032675191 0.0883484529561708 0.004980977092264 +Tdark 86 350 2.001130342432135 0.0453783452233049 74.3131067961165 324.373786407767 0.5859664552431031 0.6577158703271868 20.515717939687796 49.369088361677456 1.229854636263473 0.4013924214985833 0.999820130737216 0.9095712766071484 0.9805575228047296 0.9980407048133292 0.9999991988163248 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ee947376653b2183845fabbf71a70ec987a88ac6 --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 857.25 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1859c56113fe96b0d2ce54c129e1d5bdf7ed8197 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b32c77eb975a723ba65eb3f3bf449a0979dd4c6f --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,4 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tclin 0.4250752540338676 3.0250065435171196 0.0024862774817395 0.0099080819108992 0.0049725549634791 87 P51970,P38435,P48735,P05091,Q07864,P49721,O95168,P06280,Q9UBN7,O43676,Q99720,P21964,Q9P0J0,O75306,Q86Y39,O75438,P20618,P10253,P07437,P04350,Q9Y6M9,P55011,P03886,P00374,P31350,P42345,Q9P032,P05023,O96000,Q9Y2I1,Q13885 31 +Tdark 0.2819618257469094 2.001130342432135 0.0453783452233049 0.169527746625089 0.0605044602977399 350 Q92564,Q69YU5,O60830,Q9HD20,Q96ES6,L0R6Q1,Q96EX1,O75964,Q9Y2W6,Q9Y6I9,O43615,Q86U38,P14406,Q6IAN0,Q3SXM5,Q5VW38,Q9H4I3,Q9BXP2,Q9HD45,O43731,Q66K14,Q8N4H5,Q9NPR9,Q969T7,Q8NFH4,Q9NX00,O75071,Q15629,Q9NR77,Q9Y3A4,Q9Y320,Q8WUJ1,Q9NRY5,Q9BWJ5,P78316,Q9Y4W2,Q5SNT2,Q9BVG4,Q9H1E5,O94919,P82933,Q9NUU6,Q9P2N5,Q9Y6J9,A0AV96,O15213,Q9NPA0,P82663,Q9BYC9,Q96CN7,Q9Y6X3,O60476,Q6ZXV5,Q9Y5M8,Q1KMD3,Q96LJ7,Q9H857,Q9Y2G8,Q8WVC6,Q9BTE7,Q8N6Q8,O75935,Q9NPL8,A0AVF1,O95302,A8MXV4,Q96SK2,Q8N3Z3,Q6UW02,Q8IYR2,Q7Z2T5,Q8IZ07,Q96NB2,Q9NUD5,Q9BU23,Q9H2W6,Q9BRJ2,Q8N201,Q86YN1,Q70UQ0,Q8NBN3,Q9Y3B3,Q9NUQ9,Q9NVS2,Q96DB5,Q5HYI8 86 +Tchem 0.2450462571885925 0.898289152562184 0.3690314140929387 0.8414993855769848 0.3690314140929387 354 P21127,P30536,O75874,Q15120,P52789,Q9UIQ6,O14786,O14965,P07099,P45880,P53985,P06865,Q13315,Q9NZ45,O60502,Q6P179,P08236,P04062,P23786,P08183,O15269,P37268,P43490,Q5BJF2,Q8WTV0,P16278,P30519,O15270,P14625,Q92820,Q9H773,O15228,Q9NZ08,P13674,P09601,O60725,P42858,P42892,Q9BTY2,Q15118,P54646,P05067,O14744,P42785,Q9H7B4,Q16850,Q13535,Q5JRX3,O95470,Q9Y570,Q9H7Z7,O43865,P10619,Q15418,P46934,Q14376,Q13510,Q15904,P55899,P48729,Q13126,Q8TBX8,Q4J6C6,P53350,Q02818,Q14534,P35610,Q96K76 68 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4ad5ccb118dcafe1e569f79796343bc2e6ec8a13 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT4", "AGPAT5", "AGPS", "AGTPBP1", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "ALYREF", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APIP", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAP1", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATM", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BRMS1L", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C21orf59", "C2CD2L", "C2CD5", "C2orf49", "C3orf58", "C5orf51", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC115", "CCDC124", "CCDC127", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPU", "CENPV", "CEP170", "CEP250", "CEP290", "CEP44", "CEP55", "CEP97", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHM", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHTF18", "CHTF8", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG5", "COG7", "COG8", "COIL", "COLGALT1", "COMMD2", "COMMD7", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7A2", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF15", "DCAF16", "DCAF7", "DCAKD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX31", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND5B", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2A", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DR1", "DRG1", "DRG2", "DSC2", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD2", "EFL1", "EFR3A", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETHE1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EYA4", "EZR", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM105A", "FAM114A2", "FAM120A", "FAM120B", "FAM126A", "FAM129B", "FAM136A", "FAM162A", "FAM208A", "FAM20B", "FAM213A", "FAM49B", "FAM50A", "FAM83D", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAU", "FBL", "FBXL18", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOCAD", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FSD1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYCO1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNB1L", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPATCH4", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP6", "GTPBP8", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HP1BP3", "HPF1", "HPRT1", "HPS5", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90AB4P", "HSP90B1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS14", "INTS3", "INTS4", "INTS6", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KATNB1", "KCTD10", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA1211", "KIAA1468", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNSTRN", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC14", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRFIP1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LZTFL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP2", "METTL13", "METTL25", "METTL7B", "MFAP1", "MFGE8", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMACHC", "MMS19", "MOCS1", "MOCS2", "MOCS3", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL50", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTHFR", "MTIF2", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NET1", "NEU1", "NF1", "NFATC2IP", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PARS2", "PATL1", "PAWR", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXP", "PEBP1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHLDB2", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "POMP", "PON2", "POP1", "POR", "POU2F1", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF18", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2B", "PRRC2C", "PRUNE1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB36", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RABEP1", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAF1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RASAL2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBBP9", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RGS10", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIOX2", "RIPK1", "RMC1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL1", "SCYL2", "SDAD1", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFMBT1", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGK3", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIN3A", "SIPA1", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SMYD4", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX14", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRA1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TAPBP", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TCP11L1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFB2M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM7SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM160", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM33", "TMEM43", "TMEM87A", "TMEM97", "TMLHE", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TNRC6A", "TOE1", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TONSL", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC13", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC28", "TTC37", "TTC38", "TTC4", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR2", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP32", "USP34", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMP1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "WAPL", "WARS", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR35", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR47", "WDR48", "WDR5", "WDR6", "WDR61", "WDR62", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WLS", "WNK1", "WRAP53", "WRAP73", "WTAP", "WWP2", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO6", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YKT6", "YLPM1", "YME1L1", "YPEL5", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "AHCYL1", "ALDH2", "ANKRD13A", "APP", "ASAH1", "ATM", "ATP13A1", "ATP1A1", "ATP5L", "ATP6AP1", "ATR", "AURKA", "C12orf73", "CDK11B", "CISD1", "COMT", "COX7A2", "CPT2", "CSNK1A1", "CTSA", "CYB5D2", "CYP20A1", "CYP51A1", "DCAKD", "DCTN3", "DCTPP1", "DCUN1D4", "DCUN1D5", "DHFR", "DHRS1", "DHRS7B", "DNAJC16", "DOLPP1", "ECE1", "EFCAB14", "EMC7", "ENDOD1", "EPHX1", "ERAP1", "ERAP2", "FAM105A", "FAM114A2", "FAM49B", "FCGRT", "FDFT1", "FKBP9", "FUCA2", "GAA", "GALE", "GBA", "GGCX", "GGH", "GLA", "GLB1", "GNPAT", "GPR107", "GPR108", "GTPBP8", "GUSB", "HDAC6", "HEXA", "HK2", "HMOX1", "HMOX2", "HNRNPUL2", "HSDL1", "HSP90B1", "HTT", "ICMT", "IDH1", "IDH2", "IKBIP", "INTS1", "ISOC1", "KDELR3", "LAS1L", "LMF2", "LNPEP", "MAN1A2", "MAU2", "METTL25", "MFSD3", "MGEA5", "MRPL20", "MRPL45", "MRPL46", "MRPS18A", "MRPS25", "MRPS9", "MTAP", "MTOR", "NAMPT", "ND1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEDD4", "NISCH", "NOP14", "NOP9", "NRP1", "NT5C3B", "NT5DC2", "NUCB1", "NUDT19", "NUP37", "P4HA1", "PBDC1", "PDK1", "PDK3", "PIP4K2C", "PITRM1", "PLK1", "POLE", "PPME1", "PRCP", "PREPL", "PRKAA2", "PRMT5", "PSMB1", "PSMB2", "PTGES2", "PXMP2", "RABL3", "RBM27", "RBM47", "RMDN1", "RPS6KA1", "RRM2", "RRP7A", "SCARB1", "SF3B5", "SFXN2", "SGPL1", "SIGMAR1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC35A4", "SMIM12", "SMYD3", "SMYD4", "SOAT1", "SPTLC1", "SPTLC2", "SQLE", "SRPRB", "TAF6L", "TBC1D9B", "TDRKH", "TEX264", "TIMM17B", "TIMM44", "TIMMDC1", "TM9SF3", "TMED7", "TMEM160", "TMEM201", "TMEM209", "TMEM87A", "TMEM97", "TMTC3", "TMX2", "TMX4", "TOMM5", "TRABD", "TRAM1", "TRMT1L", "TSPO", "TTC26", "TUBB", "TUBB2A", "TUBB4A", "USP47", "VDAC2", "WDR46", "ZCCHC3"]} \ No newline at end of file diff --git a/protein_atlas_biological_process/advanced/idx2term.json b/protein_atlas_biological_process/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c220adc240438b05bfd133edaa1befebb06e9a72 --- /dev/null +++ b/protein_atlas_biological_process/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Transport", "1": "Translocation", "2": "Electron transport", "3": "Lipid metabolism", "4": "Sphingolipid metabolism", "5": "Respiratory chain", "6": "Steroid metabolism", "7": "Adaptive immunity", "8": "Ion transport", "9": "Sterol metabolism"} \ No newline at end of file diff --git a/protein_atlas_biological_process/advanced/plot_0.png b/protein_atlas_biological_process/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..809b4f64a3c6821f95a90a3d4bf7c720a7c7a9f5 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f6bb1e7b3e1a5ea97b5ccb9b22766d94d52c64eff7c6f0f01dcd3ce2b232814a +size 230176 diff --git a/protein_atlas_biological_process/advanced/plot_1.png b/protein_atlas_biological_process/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..2901ab447763791d7078169279363edfe1bdd385 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:eb2489ad7951146d62157a88b22fe6f8468c5482133cf02c96f3bdf7c58e32e9 +size 201667 diff --git a/protein_atlas_biological_process/advanced/plot_2.png b/protein_atlas_biological_process/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..58c1789bb94ca572deaaa90706dfdd0397b80644 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4a3f3ac7d8ea12fb3a66464c13b192489c7254ae1be270a58dca6d6c2c0fe7f9 +size 206103 diff --git a/protein_atlas_biological_process/advanced/plot_3.png b/protein_atlas_biological_process/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..69cbe43eb8e2407db196b462086b8e1aab328b4c --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:78fa4c1a1a6cb98b2b738746e4cc321073dc1dd6d9985e07e938c8d494688bab +size 221940 diff --git a/protein_atlas_biological_process/advanced/plot_4.png b/protein_atlas_biological_process/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..8f0ceda0dae6b37bfd001dd052d98d54f1779919 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4b6b3485e37ada5a1df4901205b460b05db4892d85f9cf6841b5643756fb9d17 +size 194186 diff --git a/protein_atlas_biological_process/advanced/plot_5.png b/protein_atlas_biological_process/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..401dac0999859140e193479935ed0244056a203f --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2ec4d9a66a480accd97606f0a21dd6b1884020a0d91990803692c75fa1caf10f +size 205879 diff --git a/protein_atlas_biological_process/advanced/plot_6.png b/protein_atlas_biological_process/advanced/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..c0325ddcbc496d34c97ad83366e7d174ac0ee62e --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5e1d14c92e0160b57412e88e102188e81916c70f96b90ea9168fb588fb34ed05 +size 203511 diff --git a/protein_atlas_biological_process/advanced/plot_7.png b/protein_atlas_biological_process/advanced/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..acdf39cf6fbebefeb8a975f75a21f6cae470738e --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:71a5f4dc9b1d27739cc22d18ebebaed3a8ac49b93945dfef33008f32011c92a0 +size 195362 diff --git a/protein_atlas_biological_process/advanced/plot_8.png b/protein_atlas_biological_process/advanced/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..e7e47489cccc47e400ce7209024be8c5cd564b69 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:67962716a08761a806729bbcccd54d7c0ba08cc6be78955833eec286ba4b360c +size 206848 diff --git a/protein_atlas_biological_process/advanced/plot_9.png b/protein_atlas_biological_process/advanced/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..ec6e82f14ba99fc3b86e96272d797739db7fc6c7 --- /dev/null +++ b/protein_atlas_biological_process/advanced/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b7eac1278d3e34d32a9f187f8af2306b59844a93e0f261882d4a0d3b3da44f00 +size 204038 diff --git a/protein_atlas_biological_process/basic/idx2term.json b/protein_atlas_biological_process/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..81aa8b9407de558df154aeeb9987c021708c0860 --- /dev/null +++ b/protein_atlas_biological_process/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Transport", "1": "Translocation", "2": "Electron transport", "3": "Lipid metabolism", "4": "Sphingolipid metabolism", "5": "Respiratory chain", "6": "Steroid metabolism", "7": "Adaptive immunity", "8": "Ion transport", "9": "Sterol metabolism", "10": "Lipid transport", "11": "Cholesterol metabolism", "12": "Steroid biosynthesis", "13": "Apoptosis", "14": "Immunity", "15": "Lipid biosynthesis", "16": "Cholesterol biosynthesis", "17": "Sterol biosynthesis", "18": "Protein transport", "19": "mRNA transport", "20": "Phospholipid metabolism", "21": "Biological rhythms", "22": "Lipid degradation", "23": "RNA-mediated gene silencing", "24": "Phospholipid biosynthesis", "25": "Innate immunity", "26": "Host-virus interaction", "27": "Angiogenesis", "28": "Cilium biogenesis/degradation", "29": "Chromosome partition", "30": "Cell adhesion"} \ No newline at end of file diff --git a/protein_atlas_biological_process/basic/plot_0.png b/protein_atlas_biological_process/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..16f449cd6af3f8d85eb77e89b05b6c79747cfad8 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bb45a261e92ce75629f032c1fdc3ac24e7641e49bf36452aeb9d6290e54fb006 +size 138955 diff --git a/protein_atlas_biological_process/basic/plot_1.png b/protein_atlas_biological_process/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..b003641d100230bcdc4f79ad89a5829c8b68768a --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a4f32032f6551c10133ade68493c69fd60c5aa8467048d25e150ed6fbc15cf6b +size 136920 diff --git a/protein_atlas_biological_process/basic/plot_10.png b/protein_atlas_biological_process/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..26506dd15f22884755d0a6b9faa7ab45be99cfa2 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ee8cc3eb01a812371d627451826dddea6fc83b541f60f3e000dca8cd38007072 +size 130053 diff --git a/protein_atlas_biological_process/basic/plot_11.png b/protein_atlas_biological_process/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..b36c4ca6b795e3cb04cd42ae7a9cfa5a7d7d795a --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0138adf41184951c5b8f44665cddbc2965fe7d87983e9c1454ddf17b2f1eb5ea +size 134208 diff --git a/protein_atlas_biological_process/basic/plot_12.png b/protein_atlas_biological_process/basic/plot_12.png new file mode 100644 index 0000000000000000000000000000000000000000..745a0b98a09444e47f535d6fcda84195c8605130 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_12.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a2bf25e649ae8f20cfa6641decf1df44ebab24adb84af95d2a59bdd6fb54f141 +size 136133 diff --git a/protein_atlas_biological_process/basic/plot_13.png b/protein_atlas_biological_process/basic/plot_13.png new file mode 100644 index 0000000000000000000000000000000000000000..cd7d94381ee86d01bb8ad0dd88137e0775b1da43 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_13.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:0458b3d8405713454a4664827ebb29df04846197ae74d0db88414490fce0751a +size 139595 diff --git a/protein_atlas_biological_process/basic/plot_14.png b/protein_atlas_biological_process/basic/plot_14.png new file mode 100644 index 0000000000000000000000000000000000000000..03db4c4bcb5824a4c9f29a30869aa86d8563df93 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_14.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ee8dc8e2342b4b06e8bb337c09fa436cd449a212574e452652d356adbe995f4f +size 133480 diff --git a/protein_atlas_biological_process/basic/plot_15.png b/protein_atlas_biological_process/basic/plot_15.png new file mode 100644 index 0000000000000000000000000000000000000000..47e8b72e49db1feda32d313ff95f80ccf2b69276 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_15.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:f4a6f2b6a079280b91d6441ed3e17b3815e9a4a21e5f0644bffd37edd6587b2d +size 132399 diff --git a/protein_atlas_biological_process/basic/plot_16.png b/protein_atlas_biological_process/basic/plot_16.png new file mode 100644 index 0000000000000000000000000000000000000000..cc95bd102310d0b3e28334ea0ce53f58354d3e91 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_16.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:821f8d310851048e910c0ffbeb0824769e7c042884eb1999d347298cc98464fd +size 136851 diff --git a/protein_atlas_biological_process/basic/plot_17.png b/protein_atlas_biological_process/basic/plot_17.png new file mode 100644 index 0000000000000000000000000000000000000000..53fa92ceb373d9a9a675cabda8789f2651257dec --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_17.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:952bd2cae36358fe47aa296fc0c9bf90b86849e2cdc87969dbaa35980ef196df +size 135771 diff --git a/protein_atlas_biological_process/basic/plot_18.png b/protein_atlas_biological_process/basic/plot_18.png new file mode 100644 index 0000000000000000000000000000000000000000..fd6cd1f27a5462d44ba41e2345ea88d3e1cd23bc --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_18.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:35c4b1762f4d3db6f15bf4f6e38f2c5cf210c38f22ef145744305bb31a3a80c4 +size 137617 diff --git a/protein_atlas_biological_process/basic/plot_19.png b/protein_atlas_biological_process/basic/plot_19.png new file mode 100644 index 0000000000000000000000000000000000000000..a4a8e478e5e402615453db01554a2a1d837e5b20 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_19.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:03895347343f105b40619a58ee802ada462a719fdbaf7c06690adddec5427ebe +size 143712 diff --git a/protein_atlas_biological_process/basic/plot_2.png b/protein_atlas_biological_process/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..f0b8b8e751b73848bfa2233613570598e5cbb5a8 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:913e3fe47fea83e71b31969e15abee9b5e9c0b2e12302459befa26cae8f34b44 +size 138057 diff --git a/protein_atlas_biological_process/basic/plot_20.png b/protein_atlas_biological_process/basic/plot_20.png new file mode 100644 index 0000000000000000000000000000000000000000..07523bbbd3b3a6053872b355c5d44f3600d117da --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_20.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1e75d88b40e721c6048366d6534028b83dd256da9b7eb07352689e82f0c2c679 +size 139116 diff --git a/protein_atlas_biological_process/basic/plot_21.png b/protein_atlas_biological_process/basic/plot_21.png new file mode 100644 index 0000000000000000000000000000000000000000..503bf94065ce042fe9c21ae7c69cc7e9e63552a8 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_21.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3eef80515c0526b87e22716b064c9adddb63c21a9cb5770672718c817efce991 +size 150856 diff --git a/protein_atlas_biological_process/basic/plot_22.png b/protein_atlas_biological_process/basic/plot_22.png new file mode 100644 index 0000000000000000000000000000000000000000..dce901628d71796fc1b2bbb615cd942396106afc --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_22.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:35881f6c06279c5889ca4c314448e1f727a20a237444dff0656a67518d24d39b +size 138248 diff --git a/protein_atlas_biological_process/basic/plot_23.png b/protein_atlas_biological_process/basic/plot_23.png new file mode 100644 index 0000000000000000000000000000000000000000..8eb5bf2bdbd0cee988d0b233ec8c301b8b90d90c --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_23.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2209fd40d78205aa5a7805b8b93d787f91c5915c0de68c83a008d4efe4c0a4fe +size 142646 diff --git a/protein_atlas_biological_process/basic/plot_24.png b/protein_atlas_biological_process/basic/plot_24.png new file mode 100644 index 0000000000000000000000000000000000000000..ab176d784a459fb5fb2adfc6e6c36425c31d141c --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_24.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:17af58997ffdb8463121473561e038791b98baba40fed37bf514e436c6638a01 +size 144092 diff --git a/protein_atlas_biological_process/basic/plot_25.png b/protein_atlas_biological_process/basic/plot_25.png new file mode 100644 index 0000000000000000000000000000000000000000..8e979dc6c5d26c96fa908a01b680989699b9e8b1 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_25.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4be726ed813a63bc13736796bae4923ee9a3c27cce702e4e0d1aac45c9d62388 +size 143908 diff --git a/protein_atlas_biological_process/basic/plot_26.png b/protein_atlas_biological_process/basic/plot_26.png new file mode 100644 index 0000000000000000000000000000000000000000..de75d3336d58ade1b04ec7b13f2441616c402301 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_26.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:867f67b664f4730b5dd8fbc38d631caa6cb3fa2d0c7403e16403ed554826dcd4 +size 143596 diff --git a/protein_atlas_biological_process/basic/plot_27.png b/protein_atlas_biological_process/basic/plot_27.png new file mode 100644 index 0000000000000000000000000000000000000000..a44a2b548761098536fb0e1d4f1b239196e45599 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_27.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e8ba196e65218a36283ae90c47a4c2fbec12a269a22e37af076d22b6028eba30 +size 147352 diff --git a/protein_atlas_biological_process/basic/plot_28.png b/protein_atlas_biological_process/basic/plot_28.png new file mode 100644 index 0000000000000000000000000000000000000000..5ec1e0e975196f03bea020d23bd0fb40c7867fee --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_28.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:80da4577641fc04782737701a8229d5fb32ea5f32b30d174264453d7ea9a5511 +size 154500 diff --git a/protein_atlas_biological_process/basic/plot_29.png b/protein_atlas_biological_process/basic/plot_29.png new file mode 100644 index 0000000000000000000000000000000000000000..a94510f687dc7cdab4913203c8a84f1a57d12a6b --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_29.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:fdf7c6ea947640232d7d6753abefb99db999169131bfff3e1845ec7e6859dbb1 +size 147141 diff --git a/protein_atlas_biological_process/basic/plot_3.png b/protein_atlas_biological_process/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..f4a2d7f24166f131922f96e14e0669cd3f7d18cb --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b6e8677a5108302e84310bc8dcb2b59ee08f9f17f6730566d67673d79f278d7d +size 140656 diff --git a/protein_atlas_biological_process/basic/plot_30.png b/protein_atlas_biological_process/basic/plot_30.png new file mode 100644 index 0000000000000000000000000000000000000000..1f72e850a921ca1739cf421bf141cf6700c31687 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_30.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d6b37be4d503874ed775388c6c4d79170006390e044861bfb85ed3d0cb8ddbf6 +size 146423 diff --git a/protein_atlas_biological_process/basic/plot_4.png b/protein_atlas_biological_process/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..673a26e511b5ba9fab017c8a3a6395294a40af72 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:807cc903ad16fce0d6b8bfe8882e626f58f566477648dbdfed180855b2111614 +size 141700 diff --git a/protein_atlas_biological_process/basic/plot_5.png b/protein_atlas_biological_process/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..315b91d93a0ce6a5705dbfa77ae842be6f796a86 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ab87f4d09ba4bf2c8ce1a5a3bc7938f6f6d105a8c982732ac84136f072493e6 +size 139405 diff --git a/protein_atlas_biological_process/basic/plot_6.png b/protein_atlas_biological_process/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..2fd0961c4c5d1c5ccc25beccdcbcebb31d96452b --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6d92768f9af9cc097de315d3f6e25b092e9ea9b9e71c26640fe3d678750162e1 +size 135447 diff --git a/protein_atlas_biological_process/basic/plot_7.png b/protein_atlas_biological_process/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..bc1ccb29c04614ded88b0b953114d340040f98cb --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4d01429cb61c71f90f9c48bce86f006f7c772218bf9c817267a8f835fb55add3 +size 134874 diff --git a/protein_atlas_biological_process/basic/plot_8.png b/protein_atlas_biological_process/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..07e92fc13078887a4a77d0d8a728a6a13419b669 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9d69b0d9dfd2d5ec090b25a4bc1127a8540dc1f78dafe7233876707285d58005 +size 131506 diff --git a/protein_atlas_biological_process/basic/plot_9.png b/protein_atlas_biological_process/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..7f2c27fed48e4b393fd237374698929213b610b7 --- /dev/null +++ b/protein_atlas_biological_process/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:84d7a56b0124c5c8ca8db863254e296ac5e9b5ae3001f6b6dfeec0388806c5f9 +size 133581 diff --git a/protein_atlas_biological_process/consensus.joblib b/protein_atlas_biological_process/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..cca0a1d4ba419b5982172ca2583e5eaec034a60a --- /dev/null +++ b/protein_atlas_biological_process/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:50aca66fb67c69529ed920f55890608c51a2502723a5e51de5866cd160159aec +size 106015 diff --git a/protein_atlas_biological_process/df_merge.tsv b/protein_atlas_biological_process/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8ba3ee3e6277a47595e5cd648df6a04ba60f8f9a --- /dev/null +++ b/protein_atlas_biological_process/df_merge.tsv @@ -0,0 +1,13 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Transport 157 509 5.345480367108512 9.017757268406701e-08 127.39320388349516 491.7621359223301 1.4832290368286314 0.5289485259644714 40.31460927260851 50.077723312236 2.248556521823017 0.4543981544818752 1.0438801851062536e-10 1.4731949149893395e-09 3.6042946621947693e-09 6.953363259589681e-11 1.10012575122508e-09 +Translocation 19 48 3.678718311441899 0.0002344089925627 12.434466019417476 47.86165048543689 1.1297087783550883 0.3515144245437065 6.687771513864753 3.601211391947168 1.550426642680832 0.3811939235350816 3.676529320545375e-05 0.0056332205677222 0.0007740006296611 1.1460372499299876e-05 0.0002142043583912 +Electron transport 20 46 3.1928549007760902 0.0014087371432027 14.983009708737864 45.592233009708735 1.1180311721330871 0.3315827540150002 5.69510117113123 4.184313965655804 1.5984402393879058 0.3574888993156041 7.896055973549767e-05 0.0118439766153403 0.0003681825850077 0.0001227255087686 6.33317697687351e-05 +Lipid metabolism 53 135 2.889188970272184 0.0038623688898777 32.65533980582524 126.3009708737864 0.0122638234126047 0.3570579745388888 13.120525890444084 12.789813112229345 1.8284441878622113 0.3670562446523409 1.0611645723073515e-07 0.0617720958469908 4.119585239167552e-05 1.777965531968116e-05 7.563296720298416e-10 +Sphingolipid metabolism 7 9 2.842372718839582 0.0044779107305199 5.075242718446602 9.720873786407768 1.0723891387155546 0.1672146303539832 2.245095774833478 1.0461446620678432 1.744521381224598 0.248179764200939 9.033837507656304e-06 0.0038211367015083 3.0155128003151412e-05 0.0010078083449561 1.393273560220496e-06 +Respiratory chain 12 33 2.832805340219265 0.0046141474998504 10.895631067961164 31.91990291262136 1.1075564231308468 0.3095707256998049 4.44287149555612 3.6670789399383112 1.4970961025113558 0.3356221172021658 4.447038919342564e-05 0.0358926009784828 0.000316040607354 0.0001087627785303 5.600633506652172e-06 +Steroid metabolism 14 28 2.4979066530417104 0.0124929085891891 7.703883495145631 26.439320388349515 1.128083592407629 0.3052190273048834 3.279782799169419 3.1412859163137186 1.216134343451914 0.3162944576553002 2.3911789429974293e-06 0.0296703391700837 0.0020253160845859 6.375644196764208e-06 9.938980179119082e-06 +Adaptive immunity 7 16 2.4849010383830152 0.0129587453266066 4.143203883495145 13.968446601941748 0.5718686468442667 0.5057512333092327 1.8737785476971824 1.931213842986535 0.8618291696256006 0.3181645561745452 0.0197042635512613 1.0 1.0 0.0115741629942865 0.005371579016814 +Ion transport 22 49 2.36689830212516 0.0179378610962201 19.82766990291262 54.68446601941748 1.177785596906995 0.303722365376275 8.99659651977233 7.41832233515522 1.8666057057567336 0.3607289685223158 0.0431343501610485 0.0142975194976326 0.1196626533568286 0.045851735312711 0.0474599682541526 +Sterol metabolism 13 26 2.2546874807971617 0.0241529520193883 7.606796116504855 25.203883495145632 1.1785484151208083 0.2872927387372206 3.1377365577760563 3.096691699470945 1.2399567569518877 0.3064799172119154 5.911772719751657e-06 0.0230307909850112 0.0012175599782738 1.832311031353461e-05 1.4177363886845684e-05 +Lipid transport 10 24 2.2212400855458125 0.026334704501943 5.140776699029126 21.796116504854368 0.7022879686929654 0.35525802853007 2.5598823127228028 3.5727100026626353 1.209238263022456 0.2984698606617377 0.0093946814277609 0.0002779956342849 0.0037316022130222 0.0049509879168996 0.0130614889048102 +Cholesterol metabolism 12 24 2.1648982777704604 0.0303954761388103 7.111650485436893 23.79854368932039 1.169709264926864 0.2871268807807383 2.8890755390042298 2.7173834172675666 1.205315163774447 0.3061468445376054 3.3621199242267044e-06 0.0204019662414969 0.0009534889418974 1.1150262559424714e-05 4.637471222605554e-05 diff --git a/protein_atlas_biological_process/metrics.json b/protein_atlas_biological_process/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..fa640e0cb365e0ddf52d20677f66f1d5140d597f --- /dev/null +++ b/protein_atlas_biological_process/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 170, + "title": "Average number of proteins per term", + "value": 32.49411764705882 +} \ No newline at end of file diff --git a/protein_atlas_biological_process/paths.json b/protein_atlas_biological_process/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e83c2bfeb5da227e189237f8973f55747ddb1053 --- /dev/null +++ b/protein_atlas_biological_process/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_biological_process/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_biological_process/result.tsv b/protein_atlas_biological_process/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..9265afefde89e71807cb0d0d8f40dc4c62809b1f --- /dev/null +++ b/protein_atlas_biological_process/result.tsv @@ -0,0 +1,63 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport 0.4101378390770835 5.345480367108512 9.017757268406701e-08 1.5330070540948656e-05 1.533018735646139e-05 509 Q9BQE5,P24390,Q9NS69,P61916,P21796,P51798,Q9UBX3,O43169,P45880,Q70HW3,O95168,O60830,O43676,Q16134,Q96FV9,Q9C0H2,Q9H0U3,Q99720,Q14849,Q9Y6M7,P00403,Q9UGP8,O00461,Q13190,P23786,Q9HD20,Q96ES6,Q12768,Q7Z3B4,Q99567,Q96SU4,Q9Y619,Q9H2V7,O75964,Q9H2D1,P28288,O95864,O43681,Q8TB61,Q9Y5J7,Q13505,O43615,Q9BSK2,A6NIH7,Q6NUK1,Q9H2U1,P55011,O43808,O15127,P03886,Q9UDW1,Q99595,Q6DKK2,Q9C0E2,Q9BXP2,Q99523,Q6P4Q7,Q9BTX1,Q8N1F7,Q9Y2T2,Q9HAV4,O43731,Q9BUR5,Q8N4H5,Q9Y282,P05023,Q9HD47,O96000,Q8NFH4,O15118,Q15629,P52294,Q08211,Q9Y584,O95487,Q9Y5L4,Q14728,Q8TD16,Q9P2W9,O95197,P24539,Q9Y6C9,Q9Y5X2,Q9UM00,Q9HCU5,Q5SRE5,O14949,Q9BQT8,Q9P0J0,P35658,P08183,Q4KMQ2,Q96KP1,Q86Y39,P11166,P06576,Q9H1E5,O75438,Q9Y487,O95249,P49257,Q9UJS0,P21912,Q15043,O75746,Q9Y5J9,P51572,O60684,Q06787,O14925,Q92973,Q03519,Q00325,P12235,Q03518,Q93050,Q6P4A7,P46379,O14678,Q96CU9,P16615,P53985,Q15907,P08574,Q9Y277,P22059,P49321,Q9Y6M9,Q969Q5,A0AVF1,O15397,Q96L92,Q9NZJ7,P22626,P41208,Q96RL7,Q9BUN8,P20020,P51970,P30825,O95202,Q96NB2,O75306,P12236,Q13277,Q9UPT5,Q8NE01,Q6NUQ1,Q9BZF1,Q92945,Q9Y3B3,O43772,Q96D46,Q12769,Q15904,Q8N5M9,Q9NUT2 157 +Translocation 0.564717118244448 3.678718311441899 0.0002344089925627 0.039070467544139 0.0039548115594776 48 Q8TD16,Q9NS69,O60830,Q5SRE5,Q7Z3B4,Q99567,Q9Y5J7,O43615,Q9Y5J9,O14925,Q99595,P41208,Q9BTX1,Q8N1F7,Q12769,Q8NFH4,Q15629,Q9Y584,Q9Y5L4 19 +Glyoxylate bypass 0.9973745624270712 3.398325652841282 0.0006779966221959 0.1088999036099747 0.0082328161266647 2 O75874 1 +Electron transport 0.517975463549939 3.1928549007760902 0.0014087371432027 0.2131000436118724 0.0126044902286564 46 P51970,Q96CU9,O43169,O95168,O43676,Q16134,O14949,P00403,Q9P0J0,O75306,Q86Y39,P08574,O75438,Q9H1E5,O95864,Q9Y6M9,P03886,Q9UDW1,Q6DKK2,O96000 20 +Peptide transport 0.936697782963827 3.1315011215976045 0.0017391512175843 0.2561479343821581 0.0140788431899688 2 Q03519 1 +Lipid metabolism 0.3907997566334493 2.8891889702721834 0.0038623688898777 0.4820486741883448 0.0211807326219104 135 Q06136,O76062,Q53GQ0,P61916,Q9NP80,O14734,O00767,Q06520,Q8NCG7,Q15392,Q96K12,O15254,P04062,P23786,O15269,Q8N2A8,P07602,P37268,Q9P035,O14975,O15270,O95864,Q8NHP8,A1L0T0,O75477,Q96N66,Q15067,P17900,Q709F0,P54646,Q9NWU1,Q99519,Q16850,O75845,O95470,Q9H7Z7,Q15800,Q8NCC3,Q9NPH0,Q14739,Q9UG56,P48651,Q13510,Q9NUQ2,P51648,Q9UBM7,O15118,P27544,Q8NF37,Q16836,P35610,Q96G23,Q9NZ01 53 +Sphingolipid metabolism 0.8748939767592011 2.842372718839582 0.0044779107305199 0.5337131715922989 0.0230680249754058 9 Q06136,P17900,O15269,P07602,O95470,Q13510,P04062 7 +Respiratory chain 0.5587181129096601 2.8328053402192652 0.0046141474998504 0.5444365804840421 0.0230707374992522 33 P51970,Q9Y6M9,Q86Y39,P03886,P08574,Q9UDW1,Q96CU9,Q6DKK2,O43676,O14949,P00403,Q9P0J0 12 +Steroid metabolism 0.5569323044909615 2.4979066530417104 0.0124929085891891 0.8820119793651706 0.0500596730472253 28 O76062,P37268,P61916,P54646,O15118,Q06520,Q16850,O75845,Q15392,Q15800,O75477,P35610,Q14739,P04062 14 +Adaptive immunity 0.6840961023480223 2.4849010383830152 0.0129587453266066 0.8911065288561496 0.0500596730472253 16 P10321,P01889,P04439,Q03519,P04083,Q9NZ08,Q03518 7 +Peroxisome biogenesis 0.7823803967327883 2.4127149336667686 0.0158341984282337 0.9336859017157846 0.0538362746559947 2 O14734 1 +Ion transport 0.4381152769436058 2.36689830212516 0.0179378610962201 0.9539081024703352 0.0587732088363156 49 P20020,P21796,P24539,P51798,P16615,P45880,Q9UM00,O95202,Q9C0H2,Q9Y6M7,Q4KMQ2,Q9Y487,O75964,Q8NE01,Q9Y277,Q15043,P55011,Q6P4Q7,Q93050,P05023,Q15904,Q9NUT2 22 +Sterol metabolism 0.5444353950976016 2.2546874807971617 0.0241529520193883 0.9843361701753176 0.0760370711721486 26 O76062,P37268,P61916,P54646,O15118,Q16850,O75845,Q15392,Q15800,O75477,P35610,Q14739,P04062 13 +Lipid transport 0.5563377961667646 2.2212400855458125 0.026334704501943 0.9892935027025092 0.0799446386666129 24 Q9BQE5,Q4KMQ2,Q9BZF1,P61916,Q96SU4,Q9H2V7,O15118,Q99720,Q14849,P22059 10 +Cholesterol metabolism 0.5489095594801632 2.1648982777704604 0.0303954761388103 0.9947387658818164 0.0890901886827199 24 O76062,P37268,P61916,P54646,O15118,Q16850,Q15392,Q15800,O75477,P35610,Q14739,P04062 12 +Prostaglandin biosynthesis 0.7036172695449154 2.0225813018827443 0.0431163335813762 0.9994427449111116 0.1163456620449834 2 Q9H7Z7 1 +Transcription termination 0.672403733955658 1.863791264188464 0.0623510230093518 0.9999823457894556 0.1604957348332071 2 Q08211 1 +Potassium transport 0.8118950887828809 1.8298115674738409 0.0672781204891617 0.9999927911173898 0.1661256259643939 4 P55011,Q9NUT2 2 +Sodium transport 0.8116616751302963 1.8288141135394833 0.067427459950254 0.9999929847045176 0.1661256259643939 4 Q9Y6M7,P55011 2 +Ubiquinone biosynthesis 0.7344616282462777 1.8127032522285431 0.0698776026184468 0.9999955144325072 0.1697027492162281 3 Q5T2R2,Q86YH6 2 +Antiport 0.782189781021881 1.7813016734417793 0.0748631812694318 0.9999982010705956 0.1792498706451184 5 P12235,P12236,P51798,O95202 4 +Phagocytosis 0.6470245040840178 1.733107703823771 0.0830765273473641 0.9999996049742644 0.1961529117923875 2 Q96JJ3 1 +Symport 0.7438286544257374 1.692564610654708 0.0905383720419987 0.9999999015207794 0.2046464244828414 6 P53985,Q9Y6M7,Q00325 3 +Steroid biosynthesis 0.4933210887691542 1.68441928070424 0.0921006671916375 0.9999999264794952 0.2046464244828414 23 O76062,P37268,Q53GQ0,P54646,Q16850,Q15392,Q15800,Q14739 8 +Apoptosis 0.3192988867285374 1.6458933326611296 0.0997857218878366 0.999999982669844 0.2120446590116528 132 P46379,P21127,O95197,P52756,P21796,O75940,Q5J8M3,Q96FV9,Q9P0J0,Q9UBK9,Q14457,O95831,P12236,O43683,Q96J02,O14737,Q9UDX5,Q03164,Q96KA5,Q01085,Q9BXK5,Q9NR28,P09601,P42574,P42858,P51572,Q969H8,P31483,P05067,Q15041,Q9NZJ7,O95470,Q96A26,Q07021,Q9Y2I1,Q9UHX1,Q07820,O60313,Q14728 39 +Vision 0.6812450114705846 1.5852846550960835 0.1129016738779515 0.9999999985704506 0.2231777274331601 7 O60313,P50897 2 +Sensory transduction 0.6812450114705846 1.5852846550960835 0.1129016738779515 0.9999999985704506 0.2231777274331601 7 O60313,P50897 2 +Amino-acid transport 0.7178793038543891 1.5728924734519505 0.1157437181801461 0.9999999991715122 0.2235958192116459 6 Q6P4A7,Q9H9B4,P30825,Q96NB2 4 +Immunity 0.3257865786025568 1.564002425086316 0.1178169989065816 0.999999999444126 0.2239394012493427 84 P46379,P10321,Q92974,P04083,Q6P179,Q9BQ95,Q9NUD5,Q96J02,Q9UQ84,Q9NZ08,Q9H2U1,P23246,P43243,Q03519,Q03518,O00584,Q96PK6,P01889,P04439,Q08211,Q8IV08,Q8N5M9 22 +Unfolded protein response 0.6362302468428579 1.5608626836363848 0.1185561536025932 0.9999999995179516 0.2239394012493427 8 Q15629 1 +Calcium transport 0.7105730217244097 1.5390460339068084 0.123793058356503 0.99999999982496 0.2312617573692913 6 P20020,Q9UM00,O95202,P16615 4 +Lipid biosynthesis 0.3576707517559997 1.4591324960389729 0.14452864373524 0.999999999997015 0.2586302045788505 55 Q53GQ0,Q9NZ01,O00767,Q15392,Q96K12,Q9P035,P37268,O95864,Q96N66,P54646,Q9NWU1,Q16850,O75845,Q9H7Z7,Q15800,Q14739,Q9UG56,P48651,Q9NUQ2,Q9UBM7,P27544,Q8NF37,Q96G23,O76062 24 +Cholesterol biosynthesis 0.5281408097299017 1.4105400941844293 0.1583802662278719 0.999999999999814 0.274117638358108 15 P37268,P54646,Q16850,Q15392,Q15800,Q14739 6 +Sterol biosynthesis 0.5026015074474487 1.4022004897793343 0.1608553854460577 0.9999999999998872 0.274117638358108 17 P37268,P54646,Q16850,Q15392,Q15800,Q14739,O76062 7 +Protein transport 0.2779207314352591 1.35483895478953 0.1754688724026487 0.9999999999999944 0.2953436466183197 274 P24390,Q9NS69,O60830,Q9UGP8,Q9HD20,Q12768,Q7Z3B4,Q99567,Q9Y5J7,Q13505,O43615,A6NIH7,O15127,Q99595,Q9C0E2,Q9BTX1,Q9Y2T2,Q8N1F7,Q9HAV4,O43731,Q8N4H5,Q9HD47,Q8NFH4,Q15629,P52294,Q9Y584,O95487,Q9Y5L4,Q8TD16,Q9P2W9,Q9Y5X2,Q9HCU5,Q5SRE5,P35658,Q96KP1,O95249,P49257,Q9Y5J9,P51572,O60684,O14925,Q92973,Q03519,Q7Z3C6,Q03518,Q9H4A6,Q92621,Q12907,O94832,Q99442,Q15907,O43707,Q15363,Q96QU8,P49321,Q969Q5,A0AVF1,O15397,Q96L92,Q99584,P41208,P49792,P0CG08,O00186,Q9Y5W7,Q96RL7,Q9BW27,Q9BUN8,O15078,O75165,Q9H267,Q86Y82,Q15388,Q9Y5X3,A2RRP1,P49755,O14964,Q9UPT5,Q6NUQ1,Q9Y3B3,Q96D46,Q12769,Q8N5M9 83 +mRNA transport 0.3353188916072078 1.209427071353688 0.2264988134538295 1.0 0.3598579279172992 63 Q8TD16,P41208,Q12769,Q7Z3B4,Q99567,Q06787,Q8NFH4,Q92945,Q08211,Q96FV9,Q5SRE5,Q9BTX1,P22626,Q8N1F7 14 +Phospholipid metabolism 0.4924302891367847 1.0520225273436157 0.2927892142332338 1.0 0.4566437286206398 13 Q9UG56,P48651,Q9NUQ2,Q96N66,Q9NPH0 5 +ER-Golgi transport 0.3229319492740128 1.018680329149899 0.3083547542342395 1.0 0.4765482565438247 51 O43731,Q9Y282,Q9P2W9,P24390 4 +Proline biosynthesis 0.5644930965995417 1.0039742253368718 0.3153910372831614 1.0 0.4815709300828995 3 P54886 1 +Glycogen biosynthesis 0.6214056814053698 1.0000831706345248 0.317270259819322 1.0 0.4815709300828995 4 Q04446 1 +Biological rhythms 0.3194038295990846 0.9759162757993908 0.3291059558746783 1.0 0.4907720394622396 51 P42345,Q00839,P43490,P23246,P17844,Q03164,P54646,O14744,Q9UNS1,P78527,Q14103,Q08211,O75592,Q9Y5V3 14 +Lipid degradation 0.4115852409271947 0.9221678817483628 0.3564410134894997 1.0 0.5226552911895893 19 Q8N2A8,Q9NP80,Q06520,Q8NHP8,Q8NCC3 5 +RNA-mediated gene silencing 0.3868974900596801 0.8166812824487656 0.4141105906332936 1.0 0.5770393476037697 22 Q9HAV4,Q9HCE1,Q06787,Q9Y2W6,O75569,Q9BWF3 6 +Notch signaling pathway 0.5071023190390315 0.7271603769269208 0.467127715822127 1.0 0.6252890684233195 7 Q9UBV2,P05067 2 +Phospholipid biosynthesis 0.4217235321793459 0.5856022621615606 0.558142827840991 1.0 0.7106502761804507 12 Q9UG56,P48651,Q9NUQ2,Q96BW9,Q8NF37,Q96N66 6 +Tricarboxylic acid cycle 0.36080100358657 0.5791272960563939 0.5625032832250905 1.0 0.7106502761804507 20 O75874 1 +GPI-anchor biosynthesis 0.5068684049164418 0.5621804447781494 0.5739930834987133 1.0 0.7174913543733915 5 O43292 1 +Hydrogen ion transport 0.3585875106376505 0.5468860214696034 0.5844570397820186 1.0 0.7199833098763997 19 P24539,Q9Y487,O75964 3 +Spermatogenesis 0.3246460673022575 0.4834310820666381 0.6287896831588302 1.0 0.7581152208297952 27 P46379,Q9UHJ3,Q9Y2W6,Q8N2A8 4 +Meiosis 0.3553545202964621 0.4691409946027511 0.6389688583598465 1.0 0.7649627177547458 18 O94901,Q9UQ84,Q8N2A8,Q9UH99 4 +Autophagy 0.2928113569633609 0.3868159051700094 0.6988925014691489 1.0 0.8250814253455231 34 P54646,Q96GC9,P13473,Q14457 4 +Inflammatory response 0.3816219540663504 0.3227736208425865 0.7468666921156455 1.0 0.8578874166193226 10 Q8IV08 1 +Innate immunity 0.2646228079470432 0.3149510154796395 0.7527988464049367 1.0 0.8588980126767733 62 Q9H2U1,Q96J02,P23246,P43243,Q07021,P10321,Q96PK6,Q92974,P78527,P01889,P04439,Q08211,P04083,O00584,Q9BQ95,Q9NUD5,Q9Y5A9 17 +Host-virus interaction 0.2361151555165382 0.2740846608172447 0.7840195615265448 1.0 0.8786083946378714 268 P61978,O95197,P21796,P10321,P49721,P35613,O60502,Q8TAF3,Q9P0J0,Q14457,Q8WTV0,Q14108,O60506,O60684,P28072,Q06787,Q9Y2A7,P61586,Q92973,Q96PU5,P08670,Q03519,O75569,P22626,P12235,Q03518,Q8IZA0,P46934,Q9HCE1,Q9BUN8,O15118,P01889,Q15629,P52294,P04439,Q96JB5 36 +Wnt signaling pathway 0.2926276167877109 0.2086760536998226 0.8347011349725824 1.0 0.9214233308138896 25 P54646,P48729,Q6DKJ4 3 +Angiogenesis 0.3228969659117821 0.1623488768550309 0.8710311270071835 1.0 0.9410177931763248 14 Q969H8,O14786,P35613,Q9BXJ9,Q08431 5 +One-carbon metabolism 0.3373237884771276 0.1508064392734223 0.8801284065590331 1.0 0.9410177931763248 10 O43865,P00374 2 +Cilium biogenesis/degradation 0.2714344680538122 0.1269866633744274 0.8989509541763399 1.0 0.9551353888123612 28 Q15154,Q9P2S5,O14965,O95684,Q9Y5Y2,Q9Y366,O15078,Q9Y496,A6NIH7,Q7Z3E5 10 +Chromosome partition 0.2763107819387135 0.0812980037361843 0.9352049615246852 1.0 0.987483499746562 21 Q14674,Q9Y6X3,O43683,Q8NFH4,O43670,P05141,P30153 7 +Oogenesis 0.3430312373633318 0.060945746072569 0.9514024170365394 1.0 0.992260189547311 4 Q9H6S0 1 +Cell adhesion 0.2406366393201838 0.0164198768313285 0.986899422468237 1.0 1.0 37 Q08380,Q99959,P05067,Q08431,Q96GC9 5 +Porphyrin biosynthesis 0.3097767653570934 0.0162043637619349 0.9870713541428602 1.0 1.0 5 P22830 1 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..72f58accd5686536ff170bf02fa34e928ae947c9 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Bile acid catabolism", "Biological rhythms", "Biomineralization", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Carnitine biosynthesis", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyridoxine biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AARSD1", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABCE1", "ABCF3", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN4", "ACTR3", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT4", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP8", "AKAP8L", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEX1", "API5", "APIP", "APOL2", "APOO", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARG2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6IP1", "ARL8A", "ARL8B", "ARMC10", "ARMC9", "ARMT1", "ARRB2", "ARVCF", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATM", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATR", "AUP1", "AURKA", "AURKB", "BABAM1", "BABAM2", "BAG3", "BAG6", "BANF1", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCL2L13", "BCLAF1", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BMS1", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRIX1", "BRMS1L", "BSG", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C2CD2L", "C2CD5", "CACYBP", "CAD", "CALCOCO1", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CARS2", "CASP3", "CASP7", "CBL", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC86", "CCDC93", "CCNB1", "CCNB2", "CD2AP", "CD2BP2", "CD3EAP", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC40", "CDC42", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP3", "CDK9", "CDKAL1", "CEBPZ", "CELF1", "CELF2", "CENPF", "CENPU", "CENPV", "CEP250", "CEP290", "CEP55", "CEP97", "CERS1", "CERS2", "CETN2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK1", "CHEK2", "CHID1", "CHM", "CHMP5", "CHMP7", "CHORDC1", "CHTF18", "CHTF8", "CIAPIN1", "CIRBP", "CISD2", "CIT", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLPTM1", "CLPTM1L", "CLSTN3", "CLTA", "CLTC", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "COASY", "COG5", "COG7", "COG8", "COMMD2", "COMMD7", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPS7B", "COPZ1", "COQ8A", "CORO7", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CREBBP", "CRNKL1", "CROT", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CWC22", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF15", "DCAF16", "DCAF7", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENR", "DERL1", "DERL2", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DICER1", "DIDO1", "DIMT1", "DIP2A", "DIS3", "DKC1", "DLAT", "DLST", "DMAP1", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DPF2", "DPY30", "DPYSL2", "DR1", "DSC2", "DSG2", "DST", "DTL", "DTYMK", "DUS2", "DUS3L", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "ECT2", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFL1", "EFTUD2", "EHD1", "EHHADH", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELF2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC4", "EMG1", "EML4", "ENO1", "ENO2", "ENSA", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP44", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "EZR", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAM120B", "FAM162A", "FAM208A", "FAM50A", "FAM83D", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXL18", "FBXO22", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FOXC1", "FOXRED1", "FRYL", "FSD1", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCC2", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GHITM", "GID8", "GINS1", "GINS2", "GINS3", "GINS4", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIP1R", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLTF", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK1", "HPF1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF2", "ILF3", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INPPL1", "INTS3", "INTS7", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IRAK1", "IRF2BP1", "ISG20L2", "IST1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "ITSN2", "IVD", "JAGN1", "JMJD6", "JUP", "KARS", "KAT7", "KATNB1", "KCTD10", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA1468", "KIDINS220", "KIF11", "KIF1B", "KIF20A", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KIN", "KLC1", "KMT2A", "KNSTRN", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRR1", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LPCAT1", "LPCAT4", "LRP1", "LRPPRC", "LRRC41", "LRRC8A", "LRRFIP1", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MAGED1", "MAGT1", "MAP1S", "MAP3K7", "MAPK1", "MAPK3", "MAPRE1", "MAPRE2", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED4", "MESD", "MFAP1", "MFGE8", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MIA3", "MICAL3", "MICALL1", "MID1", "MIF", "MINDY3", "MKI67", "MLEC", "MMS19", "MOCS1", "MOCS3", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPHOSPH10", "MPHOSPH6", "MRE11", "MRGBP", "MRPL58", "MRPS27", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTERF3", "MTFP1", "MTHFD1L", "MTHFD2", "MTIF2", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO5A", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCKAP1", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDC80", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEK9", "NELFCD", "NELFE", "NES", "NEU1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NMD3", "NME1", "NME3", "NME7", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPLOC4", "NPM1", "NRP1", "NSA2", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NUBP2", "NUCKS1", "NUDC", "NUDCD1", "NUDT16", "NUDT21", "NUF2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGFR", "OGT", "OPA1", "ORC3", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTUD7B", "OTULIN", "OXSM", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PAPOLA", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PARS2", "PAWR", "PAXBP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDK1", "PDK3", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF2", "PHF6", "PHGDH", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIR", "PISD", "PITPNB", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLIN3", "PLK1", "PLRG1", "PMF1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POP1", "POU2F1", "PPAT", "PPID", "PPIE", "PPIF", "PPIH", "PPIL2", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R8", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKCA", "PRKCB", "PRKCD", "PRKDC", "PRKRA", "PRMT5", "PRPF18", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PWP1", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB36", "RAB3B", "RAB4A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RABEP1", "RABGAP1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RANGRF", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM7", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCOR1", "REL", "RELA", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RHOA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIOX2", "RIPK1", "RMC1", "RMDN3", "RMND1", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF2", "RPL10", "RPL13A", "RPP14", "RPP30", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RPUSD3", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A13", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SCYL1", "SDAD1", "SDE2", "SDF4", "SDHA", "SDHB", "SEC16A", "SEC22B", "SEC23A", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SELENBP1", "SENP3", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFMBT1", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3RF1", "SHMT1", "SHMT2", "SHPRH", "SIGMAR1", "SIN3A", "SIRT1", "SIRT2", "SKA3", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A7", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SLU7", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX14", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SON", "SORT1", "SPAG5", "SPATA5", "SPC24", "SPDL1", "SPECC1L", "SPEN", "SPNS1", "SPTLC1", "SPTLC2", "SRA1", "SRCAP", "SREK1", "SRM", "SRPK1", "SRPK2", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX12", "STX18", "STX3", "STX5", "STX8", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "TACC3", "TAF6", "TAF6L", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TARDBP", "TARS", "TARS2", "TARSL2", "TBCB", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TDP2", "TDRKH", "TECR", "TEFM", "TENM3", "TERF2", "TERF2IP", "TEX264", "TFAM", "TFB1M", "TFB2M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TK1", "TLN1", "TM7SF2", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM214", "TMLHE", "TMX1", "TMX4", "TNPO1", "TNPO2", "TNPO3", "TNRC6A", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TONSL", "TOP1", "TOP2A", "TOPBP1", "TP53", "TP53BP1", "TPI1", "TPR", "TPRKB", "TPX2", "TRA2A", "TRA2B", "TRAF2", "TRAM1", "TRAPPC11", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIP12", "TRIP13", "TRMT10C", "TRMT11", "TRMT1L", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TSFM", "TSG101", "TSNAX", "TSR1", "TTC19", "TTC26", "TTC28", "TTC4", "TTLL12", "TTYH3", "TUBB2B", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNL1", "TXNL4A", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR2", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UCHL5", "UFC1", "UFD1", "UFL1", "UGDH", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP32", "USP34", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VIPAS39", "VIRMA", "VMP1", "VPS13A", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "WAPL", "WARS", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WDR12", "WDR33", "WDR35", "WDR36", "WDR4", "WDR41", "WDR43", "WDR48", "WDR5", "WDR6", "WDR61", "WDR62", "WDR75", "WIPI2", "WLS", "WRAP53", "WRAP73", "WTAP", "WWP2", "XAB2", "XPO1", "XPO4", "XPO5", "XPO6", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YLPM1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "ZC3H11A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZMAT2", "ZMYM2", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB8", "ABCD3", "ABCD4", "ACAD11", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACTN4", "AGPAT5", "AHCYL1", "AIFM1", "ALDH18A1", "ALDH3A2", "ANO6", "ANXA1", "AP3M1", "APOL2", "APOO", "APP", "ARHGEF2", "ARL6IP1", "ARMC9", "ASAH1", "ASNA1", "ATG9A", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5B", "ATP5F1", "ATP5L", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "AURKA", "BAG6", "BCAP31", "BCL2L13", "BECN1", "BICD2", "BSG", "BUB1", "C1QBP", "CASP3", "CDK11B", "CDK5RAP3", "CEP290", "CERS1", "CERS2", "CETN2", "CLCN7", "CLPTM1L", "CNNM3", "CNNM4", "COX2", "CPT2", "CSNK1A1", "CYB5B", "CYC1", "CYP51A1", "DAGLB", "DDX5", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHX36", "DHX9", "DIABLO", "DNAJC13", "ECSIT", "ELMO2", "EMC4", "ERAP1", "ERAP2", "ERGIC3", "ERLIN1", "ESPL1", "ETFDH", "EXO1", "EXOC2", "EXOC7", "FADS2", "FAM162A", "FAR2", "FDFT1", "FECH", "FGFR1OP", "FMR1", "FOXRED1", "GBA", "GBE1", "GM2A", "GOLIM4", "GOLPH3", "GOSR1", "GPAA1", "GPR89B", "HACD3", "HADH", "HGS", "HLA-A", "HLA-B", "HLA-C", "HMOX1", "HNRNPA2B1", "HNRNPD", "HNRNPK", "HNRNPU", "HSD17B12", "HTT", "IDH1", "IFT52", "ILVBL", "IPO8", "ITCH", "JAGN1", "KDELR1", "KDELR3", "KDSR", "KHSRP", "KIAA0319L", "KIF3A", "KMT2A", "KPNA1", "KPNA6", "LAMP2", "LBR", "LETM1", "LGALS3BP", "LMAN1", "LMAN2", "LPCAT1", "MAGED1", "MAGT1", "MATR3", "MAU2", "MBOAT7", "MCL1", "MFGE8", "MFSD10", "MFSD3", "MGEA5", "MOV10", "MSMO1", "MTCH1", "MTCH2", "MTFP1", "MTOR", "MTX1", "MYCBP2", "MYDGF", "MYO1D", "NAA15", "NAMPT", "NASP", "NBAS", "NCKAP1", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEDD4", "NEDD4L", "NEU1", "NISCH", "NMD3", "NPC1", "NPC2", "NRP1", "NUBP2", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP54", "NUP85", "NUP88", "NUP93", "NXN", "OPA1", "OSBP", "OSBPL8", "OSBPL9", "OXSM", "PCM1", "PDCD5", "PDSS1", "PDSS2", "PISD", "PKP2", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PNPLA8", "PPP2R1A", "PPT1", "PREB", "PRKAA2", "PRKDC", "PRKRA", "PRMT5", "PSAP", "PSMB2", "PSMB6", "PTDSS1", "PTGES2", "PUF60", "RAB11B", "RAB24", "RANBP2", "RANGRF", "RBM14", "RBM4", "RBM5", "RHOA", "RINT1", "RNASET2", "RTN3", "S100A13", "SC5D", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SDHB", "SEC24B", "SEC62", "SEC63", "SEL1L", "SFMBT1", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGPL1", "SIGMAR1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC2A1", "SLC35B2", "SLC39A14", "SLC4A7", "SLC7A1", "SMNDC1", "SNX14", "SNX27", "SNX5", "SNX8", "SOAT1", "SORT1", "SPNS1", "SPTLC1", "SPTLC2", "STARD3", "STX12", "STX18", "STX3", "STX5", "STXBP3", "SULT2A1", "SUN1", "SUN2", "SYNCRIP", "TAMM41", "TAP1", "TAP2", "TDRKH", "TECR", "THOC1", "TIA1", "TIAL1", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM8B", "TIMM9", "TM7SF2", "TMCO1", "TMED10", "TMED2", "TMED7", "TMX4", "TNPO1", "TOMM20", "TOMM22", "TOMM5", "TRAM1", "TTC19", "TTC26", "TTYH3", "UNC119B", "UQCR10", "UQCRQ", "UXT", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS13A", "VPS33B", "WASHC5", "WDR48", "WRAP73", "XPO4", "XPO5", "XPO6", "YTHDC2", "YTHDF2", "ZCCHC3", "ZNF207"]} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/idx2term.json b/protein_atlas_disease_involvement/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..e26eb379e10df789e521b26c68f7cfbfe5f61ad6 --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Primary mitochondrial disease", "1": "FDA approved drug targets"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/advanced/plot_0.png b/protein_atlas_disease_involvement/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..0c5802b4d0f4bada1d5989ca338ab1c7228a65bc --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ede3d593d28805f8af71b2a1a883ceba8bc05edd000f0bd6404034a8fad276d1 +size 214416 diff --git a/protein_atlas_disease_involvement/advanced/plot_1.png b/protein_atlas_disease_involvement/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..08b0db87d429918dd1768165c6a2f7a0ece4f958 --- /dev/null +++ b/protein_atlas_disease_involvement/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:79ec9aacdcb0777c87d59d9de813f0a902b7e0dd3374586f8fbbf195c7793353 +size 213999 diff --git a/protein_atlas_disease_involvement/basic/idx2term.json b/protein_atlas_disease_involvement/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..bba6555d9aa41879de3c92aecacd697413234c17 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Primary mitochondrial disease", "1": "FDA approved drug targets", "2": "Dwarfism", "3": "Neurodegeneration", "4": "Dystonia", "5": "Cataract", "6": "Congenital disorder of glycosylation", "7": "Proto-oncogene", "8": "Disease variant", "9": "Hereditary spastic paraplegia", "10": "Autism spectrum disorder"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/basic/plot_0.png b/protein_atlas_disease_involvement/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..54ec75617a2a5615bc6e00b5c87234e647acbd1e --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6401be908cc461cf8a8dbd1a7584280bd91b24b5a3db7a6391cc6fb308156c28 +size 155377 diff --git a/protein_atlas_disease_involvement/basic/plot_1.png b/protein_atlas_disease_involvement/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..5489c789b066ee1666c2f1f90cee3008f96bbb80 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:887e058a7f2a1ed3a2271c0bd1ac2d64ba5b61b98f3eb791fe1e47876d81fb12 +size 149772 diff --git a/protein_atlas_disease_involvement/basic/plot_10.png b/protein_atlas_disease_involvement/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..cc517f1dcabce0befae8d3b2648d47b8b3e2ba37 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:63e1e803e06d90e24f4919240a4c2810ef10952a40dca3d885958c0376d75e5b +size 147891 diff --git a/protein_atlas_disease_involvement/basic/plot_2.png b/protein_atlas_disease_involvement/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..5c0186dce64b7e0d6c245efb69304dd06c81fdb6 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:aad5eefa167b85d34fe18116e013a15a1cade6042cdf31afc383913471712b99 +size 139288 diff --git a/protein_atlas_disease_involvement/basic/plot_3.png b/protein_atlas_disease_involvement/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..a2142579673efb97082c7928885243e8099d7a37 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:e4482b7f3312fa329658ea31727c8f227fe0dda3df1a7a82fa2e09d4169aab99 +size 143081 diff --git a/protein_atlas_disease_involvement/basic/plot_4.png b/protein_atlas_disease_involvement/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..ae63b4adcb5c605fa3befad3a18c54620b941f97 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:cb336f2898da2b07d563e82ceb58e0d3bd77b0f6614020f99da2725695ae66ab +size 127518 diff --git a/protein_atlas_disease_involvement/basic/plot_5.png b/protein_atlas_disease_involvement/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..c36101b3e96c9d87783cb290b54986c5109a2295 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a8a08974f67298c109b530f25d125ca438ed8eafc3c2f3abd5a33ee3c5f06d51 +size 140199 diff --git a/protein_atlas_disease_involvement/basic/plot_6.png b/protein_atlas_disease_involvement/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..82ce90ffc378d87e53ddf859eb96a58695b77174 --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a21798b7e51c01f628074f5841db036c7c6d7a9de3796453cea909b1f67a18be +size 145813 diff --git a/protein_atlas_disease_involvement/basic/plot_7.png b/protein_atlas_disease_involvement/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..44e19d5faefb30cf1c85cb79ee76a2ccf71acd4e --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:50b59a2c2f80c7bbb27a0059b56cf8dc2a6e2a25b3dbd7c7443f9b9ecc3c6386 +size 148153 diff --git a/protein_atlas_disease_involvement/basic/plot_8.png b/protein_atlas_disease_involvement/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..fa85e5cdd57c2cd34312e82974cec0ed66c266bc --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:497631e57a734fffec46e85873094367741b9fc6f911309875de9c4a0e0847fa +size 136965 diff --git a/protein_atlas_disease_involvement/basic/plot_9.png b/protein_atlas_disease_involvement/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..cf641b4cf1fc0e551160be2bfe05cb983d71a08e --- /dev/null +++ b/protein_atlas_disease_involvement/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:53b0b38c47cbb5b63bd908ce955f2967cfa79c26250dd1ac4393e9a32b8d2de6 +size 151518 diff --git a/protein_atlas_disease_involvement/consensus.joblib b/protein_atlas_disease_involvement/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..db4e8a3e0e7d9a6f2e03756bdd063f0205468d10 --- /dev/null +++ b/protein_atlas_disease_involvement/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:81376960856652dd9f019f4529b3b5dd0ac0526232d4e66b710817c2d43f98a0 +size 91709 diff --git a/protein_atlas_disease_involvement/df_merge.tsv b/protein_atlas_disease_involvement/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4a088b04d9c28613df46655dce700be3b01c7e7d --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Primary mitochondrial disease 26 97 3.934762576792589 8.327897900017867e-05 27.53640776699029 92.44660194174756 0.9978626953080288 0.3665723479658412 11.863754653333944 10.66022291187525 1.7959996823414457 0.3879563837717744 1.7056662888565742e-05 0.0012969093333775 0.0012447112574106 1.380237372459007e-05 3.1086834438162414e-08 +FDA approved drug targets 27 125 2.8573158967685623 0.0042724040040902 24.04854368932039 119.4247572815534 0.6623112070438231 0.5745671660823485 8.39802177443113 10.190737689187452 0.8635117376862006 0.3683507047501689 0.0001112198026848 0.0157318056270495 0.0095199191176713 0.003002393704749 0.0007755109826739 +Mucopolysaccharidosis 3 5 2.346297867522521 0.0189609476263599 2.254854368932039 4.752427184466019 0.4843930061917075 0.2034155563537636 0.9831595235232706 0.7286567852681505 1.626107445717624 0.2463507210616131 0.0001688976199829 0.0526645480715484 0.0049445172385496 0.0020533662966424 0.00138858926748 +Gangliosidosis 3 5 2.3396191075308885 0.0193034153355369 2.8567961165048543 4.902912621359223 0.2158556094961241 0.1574800557957235 1.2213224676890235 0.2960767122713962 1.9039254823866087 0.2239345049259472 2.9242789339227067e-06 0.0002334823336694 9.025666232893031e-06 0.0001387808195727 2.661109756617399e-05 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bb223815fe879670f4aeec0046d304f3a864f27b --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 117, + "title": "Average number of proteins per term", + "value": 23.47008547008547 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e26556de73b2975a36fcb11b97b48df7ed846a53 --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..65cc16997576da9e1a0d144f13793e9a615205bb --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,43 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Primary mitochondrial disease 0.4882281088096945 3.934762576792589 8.327897900017867e-05 0.0096967268856171 0.0052072169861361 97 Q96CU9,Q9UBX3,Q70HW3,Q9Y2R0,O43676,O14949,Q9BQT8,P00403,Q9P0J0,O95831,Q99797,O75306,Q86Y39,P08574,Q9NWS8,Q9Y6M9,Q9NPL8,P03886,Q6DKK2,P13073,P12235,Q9BW92,Q6P4A7,P14854,Q9Y584,O60313 26 +Gaucher disease 0.989206534422404 3.362896317775274 0.0007712932621384 0.086321144468682 0.0150402186116993 2 P04062 1 +FDA approved drug targets 0.3943189016048903 2.8573158967685623 0.0042724040040902 0.3940405114459445 0.0357050906056112 125 P20020,O75874,P38435,P48735,P05091,P49721,P16615,Q8N0U8,Q13423,P04083,Q99707,Q99720,P21964,P23786,P12236,P10253,P07437,P03886,Q15118,P54646,P00374,P05067,Q16850,P12235,P42345,Q14534,P35610 27 +Neuronal ceroid lipofuscinosis 0.9533119346367074 2.787773838448834 0.0053071579663144 0.463447594729618 0.0382548077087192 3 O75503,P50897 2 +Niemann-Pick disease 0.8488914819136397 2.729842301420204 0.0063364628479676 0.5246600003607073 0.0405047569123878 2 O15118 1 +Hirschsprung disease 0.7972578763126993 2.484635660884779 0.0129684085291628 0.7828633068746973 0.0584406702153627 2 P42892 1 +Mucopolysaccharidosis 0.9132279885264591 2.346297867522521 0.0189609476263599 0.8935129973284457 0.0728548256212199 5 P16278,P15586,P54802 3 +Gangliosidosis 0.9116359285025633 2.3396191075308885 0.0193034153355369 0.8977753686728851 0.0728548256212199 5 P17900,P16278,P07602 3 +Leber congenital amaurosis 0.7429988331388564 2.219599006744597 0.0264459997673229 0.9565364361843424 0.0937630900841451 2 P68371 1 +Ehlers-Danlos syndrome 0.876672004428125 2.103338673545967 0.0354361751045861 0.9853200864654444 0.1219421319775465 4 Q9NWM8,Q9UL01 2 +Ichthyosis 0.6847942263235437 1.8817804184060856 0.0598658355731414 0.9992701884715228 0.1893054800556093 9 P04062 1 +Limb-girdle muscular dystrophy 0.6661470992884473 1.8522148777966687 0.0639949732047087 0.9995639390563228 0.1919849196141261 10 O14979 1 +Maple syrup urine disease 0.6406067677946329 1.6998574128512447 0.0891577491474355 0.9999820174764492 0.260786416256249 2 P21953 1 +Congenital muscular dystrophy 0.7350857635542274 1.652344936872857 0.0984642535649653 0.9999945923905516 0.2728543479641911 6 O60762,O43505,Q8NAT1 3 +Dystroglycanopathy 0.7365355144716947 1.577970968091951 0.1145722795715442 0.9999993439840568 0.2974660767911719 5 O60762,O43505,Q8NAT1 3 +Amyloidosis 0.732263342809104 1.5588111928577444 0.1190410742571188 0.9999996370788864 0.2974660767911719 5 P03886,Q9Y287 2 +Dwarfism 0.346751506867846 1.3059002310420291 0.1915864880233269 0.9999999999844 0.4075567108859863 50 Q9UG56,Q32P28,P48651,Q96L58,Q13535,Q96PZ0,O15228,Q6DKJ4,Q96HY6,O75718,Q14739,O95831 12 +Neurodegeneration 0.2989083712273468 1.283524567287295 0.1993083581973687 0.999999999994925 0.4091066299840726 139 Q15120,Q8TB36,Q13315,P06865,P50897,Q99720,P04062,O95831,P49902,O14773,O15269,Q10713,Q12768,O15270,O75477,Q9Y287,Q14108,Q96D71,Q16637,Q15043,P42858,P03886,P43243,P05067,P54802,P05023,Q96RL7,O75503,P35637,P27544,Q8IV08,Q13510,O60313,Q9Y320 34 +Dystonia 0.5663043928162479 1.2407889988429033 0.2146837062889901 0.999999999999475 0.4257287056917262 9 P04350,P51572,P11166,O75569,Q15043 5 +Lissencephaly 0.5313555398981101 1.2211852093143345 0.2220159030427981 0.9999999999998248 0.4329310109334565 12 Q6ZXV5,Q9Y320,Q8NAT1,O43505 4 +Autism 0.5665375983878551 1.1900201448981227 0.2340384743702641 0.9999999999999716 0.4488934672347689 8 O14874,P27635,Q8NDZ4,Q9NVH6 4 +Osteogenesis imperfecta 0.5515927980019683 1.1602836776083638 0.2459333278161448 0.9999999999999954 0.4640999895885314 9 O75718,Q32P28 2 +Emery-Dreifuss muscular dystrophy 0.6406834898850535 1.145275237373167 0.2520951603377268 0.9999999999999982 0.4681767263414927 5 P50402,Q8WXH0 2 +Alzheimer disease 0.6362426961254972 1.1252178406070887 0.2604967349104563 0.9999999999999996 0.4762205935081779 5 P03886 1 +Cataract 0.3737672902792298 0.9351707299031824 0.3497003203409374 1.0 0.5762667250688688 28 Q9UG56,Q9BYI3,P18074,O76024,P11166,P36776,Q8WVX9,P48449,O15228,P08670,Q5SRE5,Q15800 12 +Amyotrophic lateral sclerosis 0.445518312563639 0.7181921159081849 0.4726388385191993 1.0 0.7464506490181776 12 Q99720 1 +Alport syndrome 0.43640606767795 0.6415526071583524 0.5211637131272058 1.0 0.779625402774994 2 O60488 1 +Holoprosencephaly 0.4189031505251038 0.5584520859803451 0.5765357141323508 1.0 0.8079547436217529 2 A5YKK6 1 +Congenital disorder of glycosylation 0.3602781692850272 0.5583600138916058 0.5765985717312019 1.0 0.8079547436217529 19 O60762,Q15904,Q9BT22,P51571,P46977,Q9H0U3,Q8N511,Q2TAA5 8 +Zellweger syndrome 0.4557604806700793 0.513002170026949 0.6079498027388468 1.0 0.8082968968232395 3 P40855 1 +Peroxisome biogenesis disorder 0.4557604806700793 0.513002170026949 0.6079498027388468 1.0 0.8082968968232395 3 P40855 1 +Parkinsonism 0.4150857467538709 0.4778927112080638 0.6327265694277542 1.0 0.8232330633762568 10 P04062,Q15043 2 +Spinocerebellar ataxia 0.4013990705612722 0.4771487499000354 0.6332562025971207 1.0 0.8232330633762568 12 Q8IV08 1 +Diabetes mellitus 0.4080648882001575 0.4439130219739487 0.6571054694026903 1.0 0.8289085802346444 10 P03886,O76024 2 +Proto-oncogene 0.270163829276731 0.3924952116218897 0.6946923486837204 1.0 0.8646702637871839 54 Q06136,Q15154,O14965,P35637,P61586,Q8WY22,P46108,Q13107,O96028,Q01844,Q92733,Q92804 12 +Disease variant 0.2325887650869225 0.3046416798351549 0.7606390720359097 1.0 0.9174718703938292 872 P11177,P61916,P48735,O95630,P51798,Q9UBX3,Q7KZN9,Q70HW3,O43676,P50897,Q15392,Q16134,Q8N511,Q99720,Q9H0U3,P00403,P04062,Q9UGP8,O75844,P23786,Q13190,Q15022,Q12768,P07602,Q99567,P16278,Q9Y619,P49770,Q9H2D1,O75477,Q14108,Q16637,Q96D71,Q6NUK1,P17900,P42892,P03886,P43243,Q99959,P00374,Q9NXE4,Q9UL01,O95470,P54802,Q15800,O75718,Q6P4Q7,Q8N1F7,Q92542,Q00839,O60762,O14936,Q8NFH4,O75503,P51648,Q9Y366,O14979,O15118,Q9UBM7,Q8NAT1,Q13885,Q9UHX1,Q9Y584,Q8IV08,Q03154,P51812,Q16836,Q9H490,Q9Y320,Q9NZ01,P38435,Q13423,O14949,Q9BQT8,Q9P0J0,Q86XL3,P49902,O14773,P53701,Q9NWS8,Q96N66,Q9Y287,Q15043,O43292,P55795,Q9NVH6,Q06787,P05067,P15586,Q00325,P12235,Q14739,P10619,P52429,P16435,Q6ZXV5,P35637,P13473,Q13510,O76031,Q14738,Q06136,O14678,Q96CU9,P16615,P53985,P06865,P06280,Q15907,Q99707,P08236,Q2TAA5,Q99797,O15269,Q10713,P08574,O15270,O15228,P10253,P07437,Q15067,Q9Y6M9,P31483,P61586,Q99519,Q96L58,Q13535,P13073,P08670,O75569,P22626,Q16625,P42345,Q96AY3,Q96RL7,P48651,P14854,Q4J6C6,Q96A33,O60313,O60568,Q15120,Q8TB36,O15460,Q13315,Q6DKJ4,O95831,O75306,P50402,P46977,P22830,P42695,Q96EY8,Q9NVI7,Q8N201,P04350,P42858,O75648,Q6NUQ1,O15360,O75845,O43772,P23378,O00584,Q9BW92,Q9UG56,Q9Y2Z2,Q8TAA9,Q12769,O76024,Q14376,Q15904,Q5HYI8,Q9BT22,Q96PZ0,P27544,Q8N5M9 177 +Hereditary spastic paraplegia 0.3192609970622401 0.1920079027964629 0.8477360150692015 1.0 0.9680379801488066 16 P49902,Q12768,Q9ULH0,Q15041,O75477,P54886 6 +Microphthalmia 0.3751974342343053 0.1407038560370777 0.8881038987276582 1.0 0.9896014871536762 6 P53701 1 +Hermansky-Pudlak syndrome 0.3104756346659021 0.0686680862694752 0.945253821687235 1.0 0.9988596672687932 3 O00203,Q9UPZ3 2 +Albinism 0.3104756346659021 0.0686680862694752 0.945253821687235 1.0 0.9988596672687932 3 O00203,Q9UPZ3 2 +Glycogen storage disease 0.3088286651533896 0.0656756053421313 0.9476360945883422 1.0 0.9988596672687932 10 P10253,Q04446,P13473 3 +Autism spectrum disorder 0.2764412751543213 0.0374864007986317 0.9700971831171143 1.0 1.0 17 Q8NDZ4,Q9NVH6,Q9H2P0,P27635,O14874,Q14156 6 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c3177f81286c07b062bfdd92ab7bcd5e4668c99a --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Brugada syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hemolytic uremic syndrome", "Hereditary hemolytic anemia", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Peters anomaly", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Senior-Loken syndrome", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABAT", "ABCB1", "ABCB7", "ABCD4", "ABHD12", "ABI1", "ACAA1", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACY1", "ADAR", "ADD3", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AGTPBP1", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKAP9", "AKR1B1", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA7", "AP1B1", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "APEX1", "APOL2", "APP", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6IP1", "ARMC9", "ARPC1B", "ARSA", "ASAH1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATIC", "ATL3", "ATM", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP6AP1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATR", "ATXN10", "AURKA", "AURKB", "B3GALT6", "B4GAT1", "BAG3", "BANF1", "BARD1", "BAX", "BAZ1B", "BCAP31", "BCAS3", "BCAT2", "BCKDHB", "BCKDK", "BCLAF1", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BRI3BP", "BUB1B", "BUD23", "C19orf70", "C1QBP", "C21orf59", "C3orf58", "CAD", "CALM3", "CALR", "CAMK2G", "CANX", "CAPN1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBFB", "CBL", "CC2D1A", "CCAR1", "CCAR2", "CCDC115", "CCDC22", "CCDC47", "CCDC6", "CCNB1", "CCNB2", "CCT5", "CDC16", "CDC25C", "CDC27", "CDC37", "CDC42", "CDC6", "CDC73", "CDH2", "CDK1", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDKAL1", "CENPF", "CEP250", "CEP290", "CEP55", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK1", "CHEK2", "CHM", "CISD2", "CIT", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLIP1", "CLN5", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT3", "COA3", "COA7", "COASY", "COG5", "COG7", "COG8", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COX15", "COX2", "COX4I1", "COX5A", "COX6B1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CREBBP", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTDP1", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWF19L1", "CXorf56", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBN1", "DBT", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIS3", "DKC1", "DLD", "DLST", "DNAAF2", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DSC2", "DSE", "DSG2", "DSP", "DST", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "ECT2", "EDC3", "EEF1A2", "EEF2", "EFL1", "EFR3A", "EFTUD2", "EHHADH", "EHMT1", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "EPB41", "EPB41L3", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "ETHE1", "EWSR1", "EXOC6B", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXTL3", "EYA4", "EZR", "FABP5", "FADS2", "FAF1", "FAH", "FAM120A", "FAM126A", "FAM50A", "FAM83D", "FANCA", "FANCD2", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLCN", "FLNA", "FLNB", "FLNC", "FMR1", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FUBP1", "FUCA1", "FUS", "FYCO1", "G6PD", "GAA", "GALE", "GALK1", "GALNT2", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBE1", "GCDH", "GCLC", "GCLM", "GDAP1", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GINS1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GLUD1", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI3", "GNB1", "GNE", "GNPAT", "GNS", "GOLGA5", "GOT1", "GOT2", "GPAA1", "GPD1L", "GPHN", "GPI", "GPT2", "GRB2", "GSK3A", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2E2", "GTF2H1", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H3-3A*", "H4C1*", "HADH", "HADHA", "HADHB", "HARS2", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIP1", "HIP1R", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS5", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HSPH1", "HTT", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT52", "IGBP1", "IGF2R", "IKBKB", "ILF3", "ILK", "IMPDH2", "INF2", "INPPL1", "INTS1", "INTS12", "INTS8", "IPO7", "IRF2BPL", "IRS4", "ISCA2", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITPA", "IVD", "JAGN1", "JUP", "KARS", "KATNB1", "KDM1A", "KDM3B", "KDM5A", "KDSR", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KLC2", "KMT2A", "KNSTRN", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LDHA", "LDHB", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LIN9", "LIPA", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LRBA", "LRP1", "LRPPRC", "LSS", "LTA4H", "LZTFL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK3", "MAPKAPK3", "MARS", "MARS2", "MASTL", "MATR3", "MBD1", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM3AP", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MECR", "MED1", "MED17", "MED23", "MESD", "MFGE8", "MGME1", "MID1", "MIF", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMACHC", "MOCS1", "MOGS", "MORC2", "MPI", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTHFR", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MYH10", "MYH14", "MYH9", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCKIPSD", "NCOR1", "NCSTN", "ND1", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB3", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEDD4L", "NEFL", "NEK9", "NET1", "NEU1", "NF1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NNT", "NONO", "NOP56", "NOTCH2", "NPC1", "NPC2", "NPM1", "NRP1", "NSD2", "NSDHL", "NSMCE2", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OSBPL2", "OTULIN", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B2", "PARD3", "PARK7", "PARN", "PARP1", "PARP2", "PARS2", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PCNT", "PDAP1", "PDCD4", "PDHA1", "PDHB", "PDK1", "PDK3", "PDSS1", "PDSS2", "PEPD", "PEX14", "PEX19", "PEX5", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHGDH", "PHIP", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIK3C2A", "PIK3R2", "PISD", "PKM", "PKP2", "PLAA", "PLCG1", "PLCG2", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNP", "PNPLA4", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POLR3B", "POMGNT2", "POMP", "POP1", "POR", "PPA2", "PPFIBP1", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRUNE1", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PTDSS1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PUM1", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "RAB10", "RAB11B", "RAB18", "RAB23", "RAB3GAP2", "RAB7A", "RAB8A", "RABEP1", "RABL3", "RAC1", "RAD21", "RAD23A", "RAD23B", "RAF1", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RB1", "RBBP4", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBM7", "RBMX", "RDH11", "RDX", "REL", "RELA", "REPS1", "RFC1", "RFC2", "RHEB", "RHOA", "RINT1", "RIPK1", "RMC1", "RMND1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF213", "ROCK1", "ROCK2", "RP2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS28", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRAS2", "RRM1", "RRM2", "SACS", "SAMHD1", "SAR1B", "SARS", "SART1", "SATB2", "SBDS", "SC5D", "SCARB2", "SCO1", "SCO2", "SCRIB", "SCYL1", "SCYL2", "SDHA", "SDHB", "SEC23A", "SEC24D", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETDB1", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SIGMAR1", "SIN3A", "SIRT2", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC39A14", "SLC3A2", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SND1", "SNRNP200", "SNRPE", "SNX14", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPATA5", "SPECC1", "SPECC1L", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRP54", "SRP72", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD3", "STAT1", "STAT3", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TAF15", "TAF6", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBL2", "TCEA1", "TCF20", "TCOF1", "TDP2", "TECR", "TELO2", "TENM3", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIA1", "TIMM17A", "TIMM22", "TIMM50", "TIMMDC1", "TJP2", "TK1", "TKFC", "TKT", "TMCO1", "TMEM199", "TMEM43", "TMLHE", "TMTC3", "TMX2", "TNPO3", "TNRC6A", "TOE1", "TOM1", "TONSL", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPR", "TPRKB", "TPX2", "TRAF2", "TRAPPC11", "TRIM25", "TRIM27", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSG101", "TTC19", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWNK", "TXLNA", "TXNL4A", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBA5", "UBE2N", "UBE2T", "UBE3A", "UBQLN4", "UBR1", "UBR5", "UBTF", "UFC1", "UGDH", "UGP2", "UMPS", "UNC119", "UNG", "UPF3B", "UQCRB", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP4", "USP8", "USP9X", "UTP4", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13A", "VPS13C", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WASHC4", "WASHC5", "WBP2", "WDCP", "WDR1", "WDR11", "WDR35", "WDR36", "WDR4", "WDR5", "WDR62", "WFS1", "WIPI2", "WNK1", "WRAP53", "XPNPEP3", "XPO1", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "YARS", "YARS2", "YBX1", "YES1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "ZC3H14", "ZCCHC8", "ZMPSTE24", "ZMYM2"], "leading_proteins": ["ABCD4", "ACOX1", "ACSL4", "ACY1", "ADNP", "AIFM1", "ALDH18A1", "ALDH2", "ALDH3A2", "ALG1", "ALG11", "ANKLE2", "ANXA1", "AP3B1", "APP", "ARL6IP1", "ASAH1", "ATAD3A", "ATM", "ATP1A1", "ATP2A2", "ATP2B1", "ATP6AP1", "ATR", "AURKA", "B3GALT6", "B4GAT1", "BCAP31", "BCKDHB", "BCKDK", "BRI3BP", "C3orf58", "CASK", "CCDC47", "CERS1", "CLCN7", "CLN5", "CLPX", "CNNM4", "CNOT1", "COA3", "COMT", "COX15", "COX2", "COX4I1", "COX6B1", "CPT2", "CRK", "CRTAP", "CTSA", "CYC1", "CYP51A1", "DDRGK1", "DGKE", "DHCR24", "DHCR7", "DHFR", "DPM1", "DSE", "ECE1", "EFR3A", "EIF2B2", "EMD", "ERCC2", "ERLIN1", "ETFDH", "EWSR1", "FAM126A", "FANCA", "FAR1", "FECH", "FKBP10", "FKBP14", "FMR1", "FOXRED1", "FUS", "GAA", "GALE", "GBA", "GBE1", "GDAP1", "GGCX", "GLA", "GLB1", "GLDC", "GM2A", "GNPAT", "GNS", "GPAA1", "GUSB", "HADH", "HCCS", "HEXA", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPU", "HPS5", "HTT", "IDH1", "IDH2", "IFT52", "INTS1", "ITM2B", "JAGN1", "KDSR", "KIDINS220", "LAMP2", "LBR", "LONP1", "LSS", "MAGT1", "MATR3", "MBOAT7", "MIPEP", "MMAB", "MSMO1", "MTO1", "MTOR", "MTR", "NAGLU", "NCAPD3", "NCSTN", "ND1", "NDUFA11", "NDUFA13", "NDUFB3", "NDUFB9", "NDUFS2", "NEU1", "NNT", "NPC1", "NPC2", "NSD2", "NT5C2", "NUP160", "NUP188", "NUP37", "NUP88", "NUP93", "NXN", "OCLN", "OPA1", "P3H1", "P4HA2", "PCM1", "PDHB", "PDK1", "PDK3", "PEX19", "PIGU", "PISD", "PKP2", "PLD3", "PLOD3", "PMPCA", "POMGNT2", "POR", "PPP2R5D", "PPT1", "PRCC", "PREPL", "PRKAA2", "PRKRA", "PSAP", "PSMB2", "PTDSS1", "PUF60", "PUS7", "RAB11B", "RABL3", "REPS1", "RHOA", "RINT1", "RMND1", "RNASET2", "RPL10", "RPS6KA3", "SC5D", "SCARB2", "SEC63", "SFXN4", "SGPL1", "SIGMAR1", "SLC16A1", "SLC25A10", "SLC25A15", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A6", "SLC2A1", "SLC39A14", "SMN1*", "SMPD4", "SOAT1", "SPTLC1", "SPTLC2", "SQLE", "SSR4", "STAMBP", "STT3A", "STX5", "SUZ12", "SYNE2", "TAF15", "TARS2", "TECR", "TIA1", "TIMM22", "TIMMDC1", "TMEM199", "TMLHE", "TMTC3", "TMX2", "TPP1", "TRMU", "TTC19", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "UQCRQ", "USP4", "VANGL1", "VIM", "VKORC1L1", "VPS13A", "WASHC5", "WFS1", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_molecular_function/advanced/idx2term.json b/protein_atlas_molecular_function/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9650064dd5a15b8a517b06a1533727b62b868502 --- /dev/null +++ b/protein_atlas_molecular_function/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Receptor", "1": "Glycosidase", "2": "Translocase", "3": "Protease", "4": "Acyltransferase", "5": "Glycosyltransferase"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/advanced/plot_0.png b/protein_atlas_molecular_function/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7a57680ca1df6c2e1405fb1e429a219eba15a640 --- /dev/null +++ b/protein_atlas_molecular_function/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:db3dff411b09b99f20843e249649209817504fa6b726e06dfff9563177ab9d7d +size 198283 diff --git a/protein_atlas_molecular_function/advanced/plot_1.png b/protein_atlas_molecular_function/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..c19b36ff8e76c7f655e00ad16d72824144f3d01e --- /dev/null +++ b/protein_atlas_molecular_function/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:922dbec1a172f037c30dc85e9c447887e736d04517a8a016d379cc4e80ec7b33 +size 190003 diff --git a/protein_atlas_molecular_function/advanced/plot_2.png b/protein_atlas_molecular_function/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..41af12961d49848f6dea723afd0ae637b5ec244d --- /dev/null +++ b/protein_atlas_molecular_function/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:6a8f44a57690ddcaddd2f9cb78fb9903ad35f61f09e00f16820d1c83c135f85a +size 191147 diff --git a/protein_atlas_molecular_function/advanced/plot_3.png b/protein_atlas_molecular_function/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..323b41c9c4d5a59143ab9e566a8ab984efaac1ed --- /dev/null +++ b/protein_atlas_molecular_function/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2a53fa5836175ab59cac24338da10ec908f5cd3a4b74fdcc7881296698099de4 +size 205592 diff --git a/protein_atlas_molecular_function/advanced/plot_4.png b/protein_atlas_molecular_function/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..bcf7d22f52741463f9cf2b525b488fe015499756 --- /dev/null +++ b/protein_atlas_molecular_function/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:12c58b695ee1ce5b64a78dd1b670a3345aae2af08ee1b1578c10f5dc69c34baf +size 200360 diff --git a/protein_atlas_molecular_function/advanced/plot_5.png b/protein_atlas_molecular_function/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..e1da9760d65c3ddc04e1d1b529acd1c894627aa0 --- /dev/null +++ b/protein_atlas_molecular_function/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8965c7f8763ef981cf5d0f2360b15236b16e83e6ae5a99126b4f02c90e4d37b8 +size 201139 diff --git a/protein_atlas_molecular_function/basic/idx2term.json b/protein_atlas_molecular_function/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..65ef02c99ca89c19abac11874ecd0f26e4a09d48 --- /dev/null +++ b/protein_atlas_molecular_function/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Receptor", "1": "Glycosidase", "2": "Translocase", "3": "Protease", "4": "Acyltransferase", "5": "Glycosyltransferase", "6": "Metalloprotease", "7": "Host cell receptor for virus entry", "8": "Oxidoreductase", "9": "Heparin-binding", "10": "Methyltransferase", "11": "Hydrolase"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/basic/plot_0.png b/protein_atlas_molecular_function/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..8a6e7a819d35ea4301463f1606db62e2be3cf596 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2e0fb6bb86306e9ba694f1ecae353f18d83bc0945dbbba55ed15cf5e1d63b162 +size 137734 diff --git a/protein_atlas_molecular_function/basic/plot_1.png b/protein_atlas_molecular_function/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..bbc22954530a21d05f9c9cd25e9323799fc6bb95 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:52eb387a539f9f921e70b385c8a84e61d572697cf98e018c849a73956b967182 +size 140216 diff --git a/protein_atlas_molecular_function/basic/plot_10.png b/protein_atlas_molecular_function/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..9a56f7283792d619baa84cfef7dee8409807bf1b --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2eeab9c67fcf1e3ff3cb4d5b082e25f7bc4ef7b930547d98f78606ef976c1e09 +size 142982 diff --git a/protein_atlas_molecular_function/basic/plot_11.png b/protein_atlas_molecular_function/basic/plot_11.png new file mode 100644 index 0000000000000000000000000000000000000000..8d7985093a2a0447e3b5ff584466e382a4fb5090 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_11.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:be076f268d34337d4f56cff828d7321d6387e4d3855c4eb63dde4b5e59a546f4 +size 134803 diff --git a/protein_atlas_molecular_function/basic/plot_2.png b/protein_atlas_molecular_function/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..06ad34f3928c57830a6e14615ab744cbae4842c4 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a1de390415a7aa9dc1023d8d3a8d2c606120a229ab6cc430e205567a5e9ed405 +size 135516 diff --git a/protein_atlas_molecular_function/basic/plot_3.png b/protein_atlas_molecular_function/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..03200d489a1668e33476d50824dfb16e8787bbfe --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:726d5da52aa9023a57fe6e271fae7e80a62167c95967a7e4c88f39d9b19900b9 +size 142564 diff --git a/protein_atlas_molecular_function/basic/plot_4.png b/protein_atlas_molecular_function/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..ba09f67bccda564befecba545d00e044a75d9fa8 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:91de41b05289c1dbad11ef469fcd91540021b6331ab9b9c5a994fbcbf48132cb +size 140168 diff --git a/protein_atlas_molecular_function/basic/plot_5.png b/protein_atlas_molecular_function/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..c0584df3826fe77b9bab5bc69564908ed60b37e3 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:00ba0d28f8866f9e79ea31e7b1036a5fd426ba8b378e5e66cc970b6be85deb72 +size 135868 diff --git a/protein_atlas_molecular_function/basic/plot_6.png b/protein_atlas_molecular_function/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..ab267a71e094607d30f15812a156ab2bed7019bc --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:94a5d5abe66b2fc7e32ffbd2ade27b4826d402726a2fc3ae6d9e586cd1328b3a +size 133583 diff --git a/protein_atlas_molecular_function/basic/plot_7.png b/protein_atlas_molecular_function/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..3452ed357d4d939adc2d82c70dcb85b922ed8d4d --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:07f69b6b64111d5234edcb17950eb2e4d711b57facb50441ebe377f29742dce1 +size 136190 diff --git a/protein_atlas_molecular_function/basic/plot_8.png b/protein_atlas_molecular_function/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..61d531c632e09cab8ef24dc724f64fbb599102ab --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b25aa19a4468940c012bff34d3249c03b47b4509bb4b99510862c6f695c0458f +size 142366 diff --git a/protein_atlas_molecular_function/basic/plot_9.png b/protein_atlas_molecular_function/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..31f96313f3cff05cbdac3ab79e5eb3c5ee595218 --- /dev/null +++ b/protein_atlas_molecular_function/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:068dab47a2280287ab14d6f924d93011de283563c7d869899da9860deb725eed +size 129640 diff --git a/protein_atlas_molecular_function/consensus.joblib b/protein_atlas_molecular_function/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..5aba69a176dd53f04b2457e23ed59d5b1b667792 --- /dev/null +++ b/protein_atlas_molecular_function/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:bee14a86be8aa7c1191642ac68f3f0e657bab9b8a358311aea70def2d5c67b46 +size 88416 diff --git a/protein_atlas_molecular_function/df_merge.tsv b/protein_atlas_molecular_function/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..329f2d996c2c3b311415e96ef5d27c3e2fc12982 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,8 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Receptor 19 42 4.194526295658827 2.734424305383953e-05 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.0233232404887292 0.123613049261554 0.0361085498684405 0.0197004275225365 0.3321366122796788 +Glycosidase 10 19 3.4513599429145887 0.0005577691624096 7.798543689320389 18.135922330097088 0.5112745472223946 0.1951515073440806 2.9064203812520417 1.9684331341643595 1.9501681029822375 0.2619382904734375 2.2471112382169577e-06 0.0187248462666395 0.0085040146639909 0.00057064251751 4.502168619247678e-06 +Translocase 10 23 2.7996587771349457 0.005115665108244 8.031553398058252 23.23543689320388 0.8266305625937611 0.3429767730570308 3.903132239147793 3.2553774114037415 1.2917497354360188 0.3272657999875639 0.0002446120391689 0.0348230103466341 0.0209290225413289 0.0006098715494409 0.0001266725713312 +Protease 20 84 2.7205352494895325 0.0065176322606739 20.788834951456312 82.44417475728156 1.1215350835872162 0.3507517256058336 6.07090559629836 8.079357013764625 1.4678877461728397 0.3691345771929886 0.0125193963399915 0.3117868424794101 0.1892390391577931 0.0108104739074006 0.004071844294569 +Carboxypeptidase 4 7 2.1647465430871 0.0304071006291413 3.1359223300970873 6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 0.0076621340630544 0.0711332726649859 0.1375212864755611 0.0052676758380378 0.0049176108076387 +Acyltransferase 10 39 2.0598425247633534 0.03941359775952 8.567961165048544 34.39320388349515 0.3097294578230991 0.5297298584890537 3.96559753433415 4.2944706407944055 0.9755344857013418 0.3286789480056776 0.063453242468103 0.3928429005031874 0.0767446240128207 0.1008932065693596 0.0098156715029369 +Glycosyltransferase 11 37 1.9773216451564972 0.048005284523126 8.383495145631068 33.63106796116505 0.9005425082235603 0.4380439374186179 3.633517034002208 4.6602851932859135 0.9766631781348049 0.3531801259598526 0.1161834886272838 0.0204090903740193 0.1115354306593847 0.0711465500702303 0.0128915807124532 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..e8ebfbbf66be98ef93dd6b9a3fa035a79230c9e4 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 94, + "title": "Average number of proteins per term", + "value": 43.57446808510638 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e76199d4ada0da7eaf055c1460226c1b262bf749 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..722c26bc721b27c6dbcadeb6398c452001adf021 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,28 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Receptor 0.6464972632867926 4.194526295658827 2.7344243053839538e-05 0.0025670933559106 0.0008567862823536 42 Q99623,P24390,Q9NS69,O14786,O00264,P35613,P30825,Q99720,Q8WTV0,Q14108,Q99523,Q14739,O43731,O15173,P78310,Q9Y2I1,P55899,Q9Y5M8,O15118 19 +Glycosidase 0.7825851768764885 3.4513599429145887 0.0005577691624096 0.0510934228724314 0.0065537876583137 19 O60476,Q9BTY2,P16278,P06865,P06280,O60502,P54802,P10253,P08236,P04062 10 +Translocase 0.6443360549231905 2.7996587771349457 0.005115665108244 0.3825188409083985 0.0379193940230628 23 P20020,P08183,Q9HD20,P03886,P08574,P16615,Q13423,Q03519,Q03518,P00403 10 +Protease 0.4038425093184268 2.7205352494895325 0.0065176322606739 0.4591767093705401 0.0408438288335565 84 Q9UIQ6,Q6P179,Q96FZ2,O75844,Q8TCT9,O14773,Q99797,Q9HB40,P67812,Q9NZ08,Q2T9J0,P42892,P28072,Q9H3G5,P42785,Q5JRX3,Q9BYT8,P10619,Q4J6C6,Q96K76 20 +Cyclin 0.7473745624270727 2.241251379249401 0.0250097964428093 0.90752513793262 0.1119486126487655 2 O95067 1 +Porin 0.9049041185993814 2.2203761611980575 0.0263932438774683 0.91907989856459 0.112771132931001 4 P21796,P45880 2 +Carboxypeptidase 0.801395806816588 2.1647465430871 0.0304071006291413 0.9451210140489088 0.1242724982234471 7 Q9HB40,P10619,Q9H3G5,P42785 4 +Acyltransferase 0.4429726396367091 2.0598425247633534 0.03941359775952 0.9771742606680418 0.1424953149767262 39 P23786,O15269,Q8NCC3,O15270,Q9BWD1,Q86UY6,O15228,O14929,Q96N66,P35610 10 +Glycosyltransferase 0.4456459984425246 1.9773216451564977 0.048005284523126 0.9901905075673042 0.1671295090805128 37 P43490,Q8N4A0,Q10472,Q96L58,O60512,P46977,Q13126,Q8NAT1,O60568,P04062,Q2TAA5 11 +Metalloprotease 0.4917739047357459 1.8946216578765331 0.0581425433957678 0.9964140274766572 0.1884620372138682 27 O75844,Q99797,P42892,Q9UIQ6,O95630,Q5JRX3,Q6P179,Q9NZ08,O75976,Q9BYT8 10 +Calcium channel 0.6715285880980186 1.859307495988814 0.062983565092578 0.9977907870445776 0.1909824231839464 2 Q9UM00 1 +Host cell receptor for virus entry 0.5631208354463932 1.7204562127192704 0.0853495465213927 0.9997719739421046 0.2343375000102371 16 P78310,Q8WTV0,O15118,P35613,Q14108 5 +Oxidoreductase 0.3072807979527321 1.70259421459903 0.088644033510852 0.9998375663997542 0.2343375000102371 179 Q06136,O75874,O76062,P11177,Q53GQ0,P36551,P48735,P05091,Q96CU9,O00767,O15460,Q8N0U8,Q16134,Q6DKJ4,Q15392,Q96K12,O15254,O95831,O75306,Q32P28,Q6ZRP7,P30519,P43304,O95864,O95881,Q8NB78,Q9UHG3,P13674,P09601,Q15067,Q6IAN0,Q9NVH6,Q709F0,P00374,Q16850,P13073,O75845,Q9BU89,Q6NUM9,Q15800,P23378,Q14739,Q8NBX0,Q14534,P16435,P51648,Q9UBM7,Q8N4Q0,Q96LJ7,Q16836,O60568,Q9NZ01,Q6UW02 53 +Serine protease 0.6375989112651741 1.629183097556161 0.1032742640146455 0.9999645182025932 0.2623724545236941 9 Q2T9J0,O14773 2 +Heparin-binding 0.624125099159767 1.4967666024082384 0.1344539992570053 0.9999987256917892 0.3240686135938076 8 O94813,O14786,P05067,P30533,P10586 5 +Monooxygenase 0.7197401734983072 1.4306676096143185 0.1525255004866261 0.999999824650682 0.3334278382730897 4 Q16850,Q6UW02 2 +Dioxygenase 0.4298509373449851 1.1143662217348518 0.2651221081604644 0.9999999999997344 0.5191974618142429 21 Q32P28,O60568,P13674,Q9NVH6 4 +Methyltransferase 0.3272255124276701 1.0742508120928185 0.2827102842434312 0.9999999999999728 0.5314953343776507 53 O60725,Q8N6Q8,Q7L592,O14744,Q9H7B4,Q8IYR2,Q6P2P2,O96028,Q7Z2T5,Q99707,P21964 11 +Hydrolase 0.2529992620836048 1.0003757668252429 0.3171286928874421 0.9999999999999998 0.5845117084592072 411 Q96DE0,Q14197,O95630,P46063,Q13107,P50897,Q8NCG7,P04062,O75844,P32321,Q16706,Q9HB40,P16278,O43681,Q8NHP8,Q8NHH9,O75976,P17900,Q9H2U1,P42892,P55786,Q9H6S0,Q5JRX3,P54802,Q8NCC3,Q9NPH0,Q969T7,Q8IV08,Q9UIQ6,Q15165,P07099,O60502,Q96FZ2,P49902,O14773,Q8N2A8,P67812,O94919,Q9H8H2,Q9NZ08,P28072,Q9BTY2,P15586,P42785,Q9NUJ1,P10619,O60476,Q9H857,Q13510,Q96K76,Q9NP80,P06865,P06280,Q15907,P08236,Q8TCT9,Q99797,Q9H773,Q9UQ84,P10253,Q2T9J0,Q9H3G5,P61586,Q99519,Q14566,Q9BYT8,A8MXV4,Q9HCE1,P11117,Q4J6C6,Q9NTK5,O60313,O14734,Q6P179,Q9H4L4,Q92820,Q86YN1,Q9Y570,O00584 79 +Guanine-nucleotide releasing factor 0.3512141512080244 0.53087514952653 0.5955052993803878 1.0 0.8611922791039454 21 Q9HD47,P80303 2 +Chloride channel 0.4519848485140629 0.3541524077783324 0.7232246681545622 1.0 0.9575087155849134 5 Q9C0H2 1 +Ion channel 0.3497540779324635 0.1945304932149253 0.8457605216136628 1.0 1.0 10 Q9C0H2 1 +DNA-directed DNA polymerase 0.4008986641816764 0.1796316107235735 0.8574417865586785 1.0 1.0 4 Q07864 1 +Signal transduction inhibitor 0.3890834792761304 0.1508298810746799 0.880109914222666 1.0 1.0 4 P49840,O43665,Q9NWT1 3 +Serine esterase 0.3451561516947873 0.0676820818080765 0.9460387132450514 1.0 1.0 5 Q9Y570,O14734 2 +Endonuclease 0.2664574913556468 0.0378025177037944 0.9698451369713754 1.0 1.0 21 O94919,Q9UQ84,Q8N2A8 3 +Prenyltransferase 0.2582349852840808 0.005018675982855 0.995995692727102 1.0 1.0 3 P49354 1 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ee1d3d667a0e6ea46f13d50d017807163a59d070 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cyclin", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "IgG-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR2", "ACTR3", "ACY1", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT4", "AGPAT5", "AGPS", "AGTPBP1", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "AMPD2", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "ANXA3", "APBB1", "APEH", "APEX1", "APIP", "APP", "APRT", "AQR", "ARAP1", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "AS3MT", "ASAH1", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASRGL1", "ATAD1", "ATAD2", "ATE1", "ATG3", "ATG4B", "ATIC", "ATL2", "ATL3", "ATM", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATR", "AURKA", "AURKB", "B3GALT6", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAP18", "BARD1", "BAZ1B", "BAZ2A", "BCAT1", "BCAT2", "BCKDHB", "BCKDK", "BCLAF1", "BCR", "BCS1L", "BDH2", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD4", "BRD8", "BRMS1L", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUD23", "BZW1", "BZW2", "CAD", "CALCOCO1", "CALD1", "CALR", "CAMK1", "CAMK2D", "CAMK2G", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBL", "CBR1", "CBX3", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC47", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CDC25C", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDCA7L", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPU", "CEP290", "CEP55", "CEP97", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK1", "CHEK2", "CHM", "CHORDC1", "CHRAC1", "CHTF18", "CHTF8", "CHUK", "CIRBP", "CIT", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLK3", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLUH", "CMAS", "CMBL", "CMPK1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNP", "COASY", "COLGALT1", "COMT", "COPA", "COPS5", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CROT", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CUL5", "CXADR", "CXorf57", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND5B", "DENR", "DERA", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH2", "DICER1", "DIEXF", "DIMT1", "DIP2A", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DR1", "DRG1", "DRG2", "DSE", "DST", "DSTN", "DTYMK", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EDC3", "EDF1", "EDRF1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EHHADH", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERO1A", "ERP44", "ESD", "ESPL1", "ETFDH", "ETHE1", "EWSR1", "EXD2", "EXO1", "EXOG", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EYA4", "FADS2", "FAH", "FAHD1", "FAM120A", "FAM120B", "FAM208A", "FAM20B", "FAM213A", "FANCI", "FAR1", "FAR2", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLYWCH1", "FMR1", "FN3KRP", "FNTA", "FNTB", "FOXC1", "FOXRED1", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNE", "GNG5", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOT1", "GOT2", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDDC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPD1", "HSPE1", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPDH2", "INA", "INF2", "INPP4A", "INPPL1", "INTS11", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRS4", "ISG20L2", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITPA", "ITPK1", "IVD", "JMJD6", "KARS", "KAT7", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KRR1", "KYAT3", "L2HGDH", "LAMP1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LEMD3", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LRP1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRFIP1", "LRWD1", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAN1A2", "MAN2A1", "MAN2B1", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MATR3", "MBD1", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCRS1", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP2", "METTL13", "METTL25", "METTL7B", "MFN1", "MGEA5", "MGME1", "MGST2", "MGST3", "MICAL3", "MID1", "MIF", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MMAB", "MMACHC", "MMS19", "MOCS1", "MOCS3", "MOGS", "MORC2", "MORC3", "MORF4L1", "MOV10", "MPHOSPH10", "MPHOSPH6", "MPI", "MPRIP", "MPST", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTERF3", "MTHFD1L", "MTHFD2", "MTHFR", "MTIF2", "MTMR2", "MTMR6", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAA40", "NAA50", "NADK2", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCAM1", "NCBP2", "NCBP3", "NCL", "NCOA5", "NCOR1", "ND1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECTIN2", "NEDD4", "NEDD4L", "NEK9", "NELFCD", "NELFE", "NES", "NET1", "NEU1", "NF1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME3", "NME7", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NRP1", "NSA2", "NSD2", "NSDHL", "NSF", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTPCR", "NUCB1", "NUCB2", "NUDCD1", "NUDT1", "NUDT16", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OTUB1", "OTUD7B", "OTULIN", "OXCT1", "OXSM", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PARS2", "PATL1", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCNT", "PCYOX1", "PDCD4", "PDCL", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDSS1", "PDSS2", "PDXDC1", "PDXP", "PEBP1", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHC2", "PHF2", "PHF6", "PHGDH", "PI4K2A", "PI4KA", "PIGK", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLRMT", "POMGNT2", "POMP", "PON2", "POP1", "POR", "POU2F1", "PPA1", "PPA2", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R8", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKCA", "PRKCB", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS2", "PRUNE1", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT1", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RAF1", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RASAL2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBBP9", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REL", "RELA", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RGS10", "RHOA", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK1", "RIOK2", "RIOX2", "RIPK1", "RNASEH2A", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPP14", "RPP30", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRM1", "RRM2", "RRP1B", "RRP7A", "RRP8", "RRP9", "RSF1", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAP18", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SATB2", "SC5D", "SCAF1", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL1", "SDE2", "SDHA", "SDHB", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETD7", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B5", "SF3B6", "SFMBT1", "SFPQ", "SFSWAP", "SGK3", "SGPL1", "SGTA", "SH3RF1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIN3A", "SIPA1", "SIRT1", "SIRT2", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A2", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SMYD4", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRA1", "SRBD1", "SRCAP", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "SSU72", "STAMBP", "STAT1", "STAT3", "STAU1", "STAU2", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SULT2A1", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAF15", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TCEA1", "TCERG1", "TCF20", "TCP1", "TDP2", "TDRKH", "TECR", "TERF2", "TERF2IP", "TFAM", "TFB1M", "TFB2M", "TFCP2", "TFRC", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TM7SF2", "TMCO1", "TMEM109", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TNRC6A", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAF2", "TRAP1", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIO", "TRIP12", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TST", "TSTA3", "TTK", "TTYH3", "TUFM", "TWF2", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBP1", "UBR1", "UBR2", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRFS1", "UROD", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP32", "USP34", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP3", "UTRN", "UXT", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VPS4B", "VPS72", "VRK1", "VRK2", "WARS", "WASF2", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR47", "WDR48", "WDR5", "WLS", "WNK1", "WRAP53", "WTAP", "WWP2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "ZADH2", "ZC3H14", "ZC3H7A", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZFR", "ZMAT2", "ZMPSTE24", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZRANB2"], "leading_proteins": ["ABCB1", "ABHD10", "ACAD11", "ACAT2", "ACOT8", "ACOX1", "ACOX3", "ACP2", "ACP6", "AIFM1", "ALDH2", "ALDH3A2", "ALG11", "APP", "ASAH1", "ASNA1", "ATL2", "ATP13A1", "ATP2A2", "ATP2B1", "B3GALT6", "B4GALT3", "BSG", "CCNB2", "COMT", "COX2", "COX4I1", "CPD", "CPOX", "CPT2", "CPVL", "CTSA", "CXADR", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DCTD", "DCTPP1", "DDX31", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7B", "DHX36", "DOHH", "DOLPP1", "ECE1", "ENDOD1", "EPHX1", "ERAP1", "ERAP2", "ETFDH", "EXO1", "FADS2", "FAR2", "FCGRT", "FNTA", "FOXRED1", "FUCA2", "GAA", "GALNT1", "GALNT4", "GBA", "GGH", "GLA", "GLB1", "GLDC", "GM2A", "GNPAT", "GNS", "GPD2", "GSK3A", "GUSB", "HADH", "HAT1", "HEXA", "HM13", "HMCES", "HMOX1", "HMOX2", "HSD17B12", "ICMT", "IDH1", "IDH2", "KDELR1", "KDELR3", "KDM1B", "KDSR", "LBR", "LNPEP", "LRPAP1", "MAN1A2", "MAN2A1", "MBOAT7", "MCM6", "METTL25", "MGEA5", "MIPEP", "MOV10", "MRPL58", "MSMO1", "MTAP", "MTR", "NAA40", "NAGLU", "NAMPT", "ND1", "NDUFAF7", "NDUFS2", "NEU1", "NISCH", "NLN", "NNT", "NPC1", "NPEPPS", "NRP1", "NSD2", "NT5C2", "NT5C3B", "NT5DC2", "NUCB2", "NUDT16", "NUDT19", "NXN", "OLA1", "OPA1", "P3H1", "P4HA1", "P4HA2", "PAK1IP1", "PCYOX1", "PDHB", "PGRMC1", "PGRMC2", "PHB2", "PITRM1", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLOD3", "PNPLA8", "POLE", "POMGNT2", "PON2", "POR", "PPME1", "PPT1", "PRCP", "PREPL", "PRMT5", "PRMT9", "PSMB6", "PTPRF", "QSOX2", "RAB11B", "RANGRF", "RECQL", "RETSAT", "RGS10", "RHOA", "RNASET2", "SC5D", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCPEP1", "SEC11A", "SENP3", "SIGMAR1", "SLC7A1", "SLIT2", "SMYD3", "SMYD4", "SOAT1", "SORT1", "SPTLC1", "SPTLC2", "SQLE", "SRPRB", "STAMBP", "STT3A", "TAP1", "TAP2", "TECR", "TM7SF2", "TMCO1", "TMLHE", "TOMM22", "TPP1", "TRMT1L", "TTYH3", "TXNDC12", "TYSND1", "USP4", "USP47", "VDAC1", "VDAC2", "VKORC1L1", "YTHDC2", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/idx2term.json b/protein_atlas_protein_class/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..2e7ba783696032f9e98151319cd2977ff917219e --- /dev/null +++ b/protein_atlas_protein_class/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins", "1": "Transporters", "2": "Predicted secreted proteins", "3": "FDA approved drug targets", "4": "CD markers", "5": "Potential drug targets"} \ No newline at end of file diff --git a/protein_atlas_protein_class/advanced/plot_0.png b/protein_atlas_protein_class/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..415ed81510663607b1d3efb91b4ebd5bbec2086f --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:95f3c035240c63dfa6e6aaf33f8ae6ad545e0f62e20a10797755a23baec14a38 +size 220508 diff --git a/protein_atlas_protein_class/advanced/plot_1.png b/protein_atlas_protein_class/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..7fa96165e032052772454b7c2560215ef5446901 --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a338b2bf2e320853753d1d1e9a564696e5bd1169775339f01da743cf6b2a6fa2 +size 212801 diff --git a/protein_atlas_protein_class/advanced/plot_2.png b/protein_atlas_protein_class/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..682f26da8eb35783c6337fb08dcd36536dcfee44 --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:00065f6d02db74c399e9029273f9af00a5a43a6b03cb695989e201ae68161e51 +size 195989 diff --git a/protein_atlas_protein_class/advanced/plot_3.png b/protein_atlas_protein_class/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..9a36ce9a5cffc1a3f33a9d9459de3419c4c68c3e --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a3c1ad083798d90d0d04e8cf4a27abd6750f00e7e8d9bee2243d1cf4b0f349be +size 203910 diff --git a/protein_atlas_protein_class/advanced/plot_4.png b/protein_atlas_protein_class/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..2f78288ec797baf2909286cf16febdec52b4859c --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7f88c1fab7d1123de1e9d67d3f9870cbcf87d1833e64fd21b3c6181e2de339d0 +size 184960 diff --git a/protein_atlas_protein_class/advanced/plot_5.png b/protein_atlas_protein_class/advanced/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..217ca25561059bfc0607bbf790698ebc2d53d6cc --- /dev/null +++ b/protein_atlas_protein_class/advanced/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:06399cafa2e0b7e3917baf5778e7d117becf3b50173c248708bcaa359ca5880d +size 215989 diff --git a/protein_atlas_protein_class/basic/idx2term.json b/protein_atlas_protein_class/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..8043daa05ec5cc703ba20630852cf80fac7959d5 --- /dev/null +++ b/protein_atlas_protein_class/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Predicted membrane proteins", "1": "Transporters", "2": "Predicted secreted proteins", "3": "FDA approved drug targets", "4": "CD markers", "5": "Potential drug targets", "6": "Human disease related genes", "7": "Metabolic proteins", "8": "Disease related genes"} \ No newline at end of file diff --git a/protein_atlas_protein_class/basic/plot_0.png b/protein_atlas_protein_class/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..2b7439dc5f5c3300c0ef1d37120bff646fe343f7 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:531219b1d0839188454c03720c0c1ce1f18bd7afaf2cb854f7faee98fc253afe +size 141803 diff --git a/protein_atlas_protein_class/basic/plot_1.png b/protein_atlas_protein_class/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..bbdbdd490c032356dfede10bdeec9fb11a3b5dcc --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:17060d06d99bf70e727933f0146ca736cda8ee6dc14f0bea1410b5007e20b97e +size 138949 diff --git a/protein_atlas_protein_class/basic/plot_2.png b/protein_atlas_protein_class/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..efcbacd08151ac318a8375f9da3478821afe1c08 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:8cdac394ddaf813cbb02102e17e87c2948cc78c49a7d2a3e4dbaf1987cffbd47 +size 145062 diff --git a/protein_atlas_protein_class/basic/plot_3.png b/protein_atlas_protein_class/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..5489c789b066ee1666c2f1f90cee3008f96bbb80 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:887e058a7f2a1ed3a2271c0bd1ac2d64ba5b61b98f3eb791fe1e47876d81fb12 +size 149772 diff --git a/protein_atlas_protein_class/basic/plot_4.png b/protein_atlas_protein_class/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..3b1c2580aaafdea7dcc659815ed94589a15cb74f --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:64b58d762536b7c6c0c75c3950357d6066b01979e6769516f3abeef4dcbcec5d +size 131576 diff --git a/protein_atlas_protein_class/basic/plot_5.png b/protein_atlas_protein_class/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..ea78ffd0d50ce0b026de08936270cb132cbeb63b --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:65f6e90e845b21adb2f2f640e2ee90e970f0cdb320c0cdf0dc05655e4210a3b6 +size 138039 diff --git a/protein_atlas_protein_class/basic/plot_6.png b/protein_atlas_protein_class/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..9c675b5bf9ed948ad5b3e2154f17483d0775d4ff --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:830699a56e53ff8d88e4f8e49c0fcc29b979fa201de28ecb7e9dbb4a6382ef47 +size 138581 diff --git a/protein_atlas_protein_class/basic/plot_7.png b/protein_atlas_protein_class/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..a041cd08492e991168afad885104fe6b9dc03964 --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:32c83b6cba19d95c87c75483e51489a3ed862607265b09e3516ae8a6e41eab60 +size 133718 diff --git a/protein_atlas_protein_class/basic/plot_8.png b/protein_atlas_protein_class/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..bf4f3b7e7c32bf1fbb7a3a961bb89f46c2a8346a --- /dev/null +++ b/protein_atlas_protein_class/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ebf15a43e02a85941d63698ea3a8250c913aef46f824757fd002657fd0bed9ad +size 137493 diff --git a/protein_atlas_protein_class/consensus.joblib b/protein_atlas_protein_class/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3e6a41a4b680df7f3cf677501ddb984123aa3186 --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:efc7f107841919e2f2716d4341f2b363e0d73b96b4b6e8bd0a14c13eebd58780 +size 105159 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ae6faab844423d5b0a21fc0a669f4831fdf12db4 --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,7 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 282 571 10.456092911486582 1.3740537019320628e-25 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 3.9493473349285757e-32 4.9564805449305045e-09 1.0183637743921695e-16 2.081535900570212e-30 1.3196994492901003e-31 +Transporters 159 369 7.109868799769216 1.1615331884216206e-12 108.9004854368932 367.3009708737864 1.469396346451591 0.4764419032567517 40.40141182476491 35.10022679965902 2.352674986871393 0.4490473364946538 5.621984883940028e-15 1.0435184117719376e-06 6.814617200066743e-07 3.823863159231399e-13 6.5567540875688265e-18 +Predicted secreted proteins 25 53 4.036152755016526 5.433484655803511e-05 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 0.0085564055629728 0.1447627069588957 0.0486330973265672 0.0024776005259076 0.038848181715856 +FDA approved drug targets 27 125 2.8573158967685623 0.0042724040040902 24.04854368932039 119.4247572815534 0.6623112070438231 0.5745671660823485 8.39802177443113 10.190737689187452 0.8635117376862006 0.3683507047501689 0.0001112198026848 0.0157318056270495 0.0095199191176713 0.003002393704749 0.0007755109826739 +CD markers 5 18 2.073069216109835 0.0381658384224254 6.548543689320389 16.62378640776699 0.159361413045758 0.3347758559744795 3.625700175504636 4.1209525283344535 1.5119526885132668 0.3016304730463651 0.5790803496616276 1.0 1.0 0.7405589746065433 0.8986690412892057 +Potential drug targets 147 526 1.9791330691681348 0.047801026121065 97.55339805825244 482.2839805825243 0.1164506319746192 0.6956405557980175 32.086496616991845 44.65677560523076 1.054724020710321 0.3686644405287784 1.570148362494092e-07 0.0006917822536265 0.0023733022754965 2.8078454859407662e-06 8.535269233927535e-12 diff --git a/protein_atlas_protein_class/metrics.json b/protein_atlas_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ec3543bc0ac32a63dfd532f7791406b9e49b0ef0 --- /dev/null +++ b/protein_atlas_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 20, + "title": "Average number of proteins per term", + "value": 548.85 +} \ No newline at end of file diff --git a/protein_atlas_protein_class/paths.json b/protein_atlas_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6003da773f49bbe596a0b3c2b2815be00ba51355 --- /dev/null +++ b/protein_atlas_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_protein_class/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_protein_class/result.tsv b/protein_atlas_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e23221045ec2917e965caf3eeebacfeb3bfc72e3 --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.6332195397102495 10.456092911486582 1.3740537019320628e-25 2.0000002748107405e-17 1.0000001374053704e-17 571 Q9BQE5,P57088,P24390,Q9NS69,O14786,Q9H061,Q9UBX3,O43169,P51798,Q70HW3,Q8N0U8,Q7KZN9,Q9Y2R0,O60830,O43676,O95168,Q15392,Q9C0H2,Q8N511,Q99720,Q14849,Q16134,P00403,Q8NCG7,O00461,O75844,Q9H0U3,Q9Y6M7,Q9HD20,P43307,Q96ES6,Q9UGP8,Q13190,Q16706,Q9UDX5,Q99567,Q6ZRP7,P30519,Q9Y619,Q9H2V7,O75964,Q9Y2W6,Q96EX1,P28288,O95864,Q9UBD5,A1L0T0,Q8TB61,Q8NHH9,Q13505,P09601,Q14108,Q9BSK2,O75976,O43657,O60725,Q6IAN0,Q3SXM5,Q5VW38,Q9H4I3,P42892,Q9H2U1,O15127,P03886,Q9UDW1,P54646,P55011,O43808,Q99595,Q9UL01,Q9NXE4,Q9BXP2,Q99523,O95470,Q6NTF9,Q15800,Q6P4Q7,Q9HD45,Q8NCC3,Q9BTX1,Q8N1F7,Q8IZA0,Q8NBX0,Q96A26,O43731,O15260,O15173,Q9NVH1,Q9BUR5,Q9Y282,Q92542,P78310,Q9NPR9,P05023,O14936,P51648,P55899,Q9UBM7,O15118,Q8WY22,O75071,Q9NX00,Q8TCJ2,Q15629,Q14BN4,Q07820,Q9Y584,Q8IV08,P51812,Q14534,Q9NR77,Q9H490,Q96G23,O60637,Q9Y320,Q9NZ01,Q14728,Q14674,Q9P2W9,O95197,Q96FV9,Q8NAN2,Q9UIQ6,P38435,P24539,P36551,O96005,P11279,O00767,O00264,Q8WVX9,Q9Y6C9,Q13423,O75448,Q9UM00,Q9HCU5,Q567V2,Q5SNT2,Q9Y262,Q8IXM6,Q9P0J0,Q86XL3,Q5VV42,P08183,Q4KMQ2,Q8N2A8,P37268,Q86Y39,Q8WTV0,P11166,Q9H1E5,O75438,P67812,Q9Y487,Q9BXK5,O94919,O95249,P49257,Q9NUU6,Q15070,Q9NWS8,Q9NR28,Q96N66,Q9Y287,Q6YHK3,Q96GC9,Q15043,Q9NPA0,O43292,P51572,O14925,P05067,Q16850,Q9NX40,Q03519,Q6NUM9,Q00325,P12235,Q03518,Q93050,Q14739,Q92804,Q96PC5,Q9NQX7,P52429,O60476,P16435,Q6P4A7,Q6ZXV5,Q9Y5M8,P13473,P57105,P04439,Q86V85,Q92544,Q9Y2G8,P35610,Q07065,Q06136,Q8WVC6,O14678,Q53GQ0,Q86UE4,Q9NP80,Q9UBU6,Q8TBA6,Q92896,P16615,P53985,P35613,Q96K12,Q2TAA5,Q8TCT9,O15269,Q9P035,Q5BJF2,P08574,O15270,Q96KA5,Q96KC8,Q9NPL8,Q9Y2A7,Q9NZJ7,Q13535,P13073,Q16625,Q9NQC3,P48651,Q9NUQ2,Q9BUN8,P04844,O94901,P01889,P11117,Q96SK2,Q96A33,O76062,Q6UW02,P20020,Q13641,Q8TB36,Q9UBV2,P10321,P51571,Q9NZ45,Q8IYR2,P30825,O95202,Q96NB2,O95831,O75306,P12236,Q9BU23,O14975,Q13277,Q9UH99,P50402,Q8NE01,P46977,Q8N201,Q5T9L3,P42858,Q86YN1,Q9BZF1,O15360,Q10472,Q70UQ0,Q8IY95,Q8NBN3,Q9Y3B3,O75845,O43772,Q9UG56,Q8TAA9,O76024,Q15904,Q9BT22,Q9NQG6,P27544,Q8NF37,Q8N5M9,Q9NUT2 282 +Transporters 0.4908557600640458 7.109868799769216 1.1615331884216206e-12 2.323068376817607e-11 7.743561256144137e-12 369 P57088,P24390,P61916,O14786,Q9H061,Q9UBX3,P51798,P45880,Q70HW3,Q9C0H2,Q8N511,Q99720,Q14849,Q9H0U3,P00403,Q9Y6M7,Q9UGP8,O75844,Q13190,Q9HD20,P07602,Q7Z3B4,Q99567,Q9Y619,Q9H2V7,Q9H2D1,P28288,O43681,Q8TB61,Q8NHH9,O75477,Q14108,Q9BSK2,Q6NUK1,Q5VW38,P55011,O43808,O15127,P54646,Q9BRK5,Q9C0E2,Q9BXP2,Q99523,Q6NTF9,Q6P4Q7,Q13438,Q9BTX1,Q8N1F7,Q9HAV4,Q9BUR5,O15260,P78310,P05023,P46934,Q8NFH4,O15118,Q8WY22,Q8TCJ2,Q15629,P52294,Q9NR77,Q9Y320,O60637,P11279,O96005,Q9Y6C9,Q9UM00,Q9HCU5,P04083,Q5SRE5,Q9BQT8,P35658,P08183,Q4KMQ2,Q96KP1,P11166,Q8WTV0,P49257,Q9UJS0,Q15070,Q9NPI6,Q96N66,Q9Y287,P21912,Q96GC9,Q15043,O75746,Q9NPA0,P51572,Q02978,O60684,P05067,Q92973,O95067,Q03519,Q7Z3C6,Q00325,P12235,Q03518,Q93050,Q96PC5,Q16543,Q92621,Q6UW68,Q6P4A7,Q6ZXV5,Q07021,P40855,P13473,P57105,P04439,Q92544,Q07065,O14678,Q9UBU6,O00560,Q8TBA6,P16615,P53985,P35613,Q9Y512,Q5BJF2,O15397,Q96L92,Q9NZJ7,P13073,Q16625,Q8IYU8,Q96RL7,Q9BUN8,P04844,O94901,Q96A33,O60313,P20020,Q9UBV2,P30825,O95202,Q96NB2,P12236,O14975,P33176,Q13277,Q9UPT5,Q9UH99,Q8NE01,P46977,Q5T9L3,Q9BZF1,Q8IY95,Q9Y3B3,O43772,O43865,Q8TAA9,Q12769,O76024,Q16891,Q15904,Q9NUT2 159 +Predicted secreted proteins 0.5932706878508194 4.036152755016526 5.433484655803511e-05 0.0010861361816329 0.0002716742327901 53 Q8WUJ1,P80303,P61916,O14786,Q15165,P04083,Q6P179,P43490,Q9HB40,Q08380,O94919,Q9UM22,O60888,Q9Y4P3,Q9NZ08,Q9Y287,Q14667,Q9BTY2,P05067,O75718,O00584,Q9BUR5,Q08431,Q02818,O60568 25 +FDA approved drug targets 0.3943189016048903 2.8573158967685623 0.0042724040040902 0.0820672388879948 0.0142413466803007 125 P20020,O75874,P38435,P48735,P05091,P49721,P16615,Q8N0U8,Q13423,P04083,Q99707,Q99720,P21964,P23786,P12236,P10253,P07437,P03886,Q15118,P54646,P00374,P05067,Q16850,P12235,P42345,Q14534,P35610 27 +CD markers 0.5866084463214808 2.073069216109835 0.0381658384224254 0.5407978021792337 0.0954145960560637 18 P08183,O14786,P11279,P13473,P35613 5 +Potential drug targets 0.288872809186169 1.9791330691681348 0.047801026121065 0.6245482070894764 0.1062245024912557 526 P11177,P61916,O95630,Q9H061,P51798,Q70HW3,P50897,Q15392,Q9H0U3,Q8N511,P00403,P04062,Q9UGP8,O75844,Q32P28,P07602,Q99567,P16278,Q9Y619,Q9H2D1,P28288,P09601,Q14108,O75477,Q6NUK1,P42892,Q9NXE4,Q9UL01,Q99523,O95470,P54802,Q15800,Q6P4Q7,Q8N1F7,O60762,O14936,Q8NFH4,P51648,Q9UBM7,O15118,Q8TCJ2,Q13126,Q8NAT1,Q03154,Q8IV08,P51812,Q9Y320,Q9NZ01,Q5JPH6,P36551,P07099,Q8WVX9,Q9UM00,Q5SRE5,Q9BQT8,P35658,Q5VV42,P49902,Q9H9P8,O14773,Q4KMQ2,Q96J02,Q96GX5,P37268,P53701,P11166,Q5T2R2,P00367,P49257,P78527,Q9NWM8,Q9UJS0,Q96N66,Q9Y287,P21912,Q15043,O75746,P51572,Q9NVH6,P15586,Q96PU5,Q03519,Q00325,Q03518,Q14739,Q96PC5,P10619,P52429,P16435,Q6P4A7,Q6ZXV5,P13473,P04439,Q13510,Q06136,O14678,Q9NP80,Q8TBA6,P53985,P06865,P06280,P08236,Q2TAA5,Q99797,O15269,Q10713,P08574,O15270,O15228,Q15067,P61586,Q99519,Q96L58,Q13535,P13073,O96028,Q16625,Q96AY3,Q96RL7,P48651,P11117,Q4J6C6,Q96A33,O60313,O60568,Q15120,O15460,Q13315,Q6DKJ4,O75306,P46977,P22830,Q96EY8,O75648,O75845,O43772,Q7L592,P23378,O00584,Q9BW92,Q8TAA9,Q12769,O76024,Q14376,Q15904,Q9BT22,P53350 147 +Human disease related genes 0.2621100133362334 1.8741068665852911 0.0609156970955828 0.7154938722711405 0.1218313941911657 1004 Q9BQE5,O75874,P11177,P61916,P48735,O95630,Q9H061,Q9UBX3,P51798,Q7KZN9,Q70HW3,Q92974,O43676,P50897,Q15392,Q16134,Q8N511,Q99720,Q9H0U3,P00403,P04062,Q9UGP8,O75844,P23786,Q32P28,Q12768,P07602,Q99567,P16278,Q9Y619,P49770,P28288,P09601,Q14108,O75477,Q16637,Q96D71,Q6NUK1,P17900,P42892,P03886,P43243,Q99959,P00374,Q9NXE4,Q9UL01,Q6DKK2,O95470,P54802,Q15800,O75718,Q6P4Q7,Q8N1F7,Q92542,Q00839,P05023,O96000,O60762,O14936,Q8NFH4,O75503,P51648,Q9Y366,O14979,O15118,Q9UBM7,Q8TCJ2,Q8NAT1,Q5XKP0,Q13885,Q9UHX1,Q9Y584,Q8IV08,Q03154,P51812,Q9NR77,Q16836,Q9H490,Q9Y320,Q9NZ01,Q8TD16,Q5JPH6,P38435,P36551,P78318,P07099,Q8WVX9,Q13423,Q9Y4W2,Q9UM00,Q9UBN7,O14949,P61313,Q9BQT8,Q9P0J0,Q86XL3,P49902,P08183,O14773,Q4KMQ2,Q5VV42,Q9H9P8,Q96J02,P53701,Q86Y39,Q96GX5,P11166,Q5T2R2,P00367,Q9Y487,P49257,P78527,Q9NWM8,Q9UJS0,Q9NWS8,Q96EK5,Q9NR28,Q96N66,Q9Y287,P21912,Q15043,O75746,O43292,P51572,P55795,Q9NVH6,Q06787,P05067,P15586,Q96PU5,Q03519,Q00325,P12235,Q03518,Q14739,P10619,P52429,P16435,Q6P4A7,Q6ZXV5,P35637,P13473,P04439,Q9Y2G8,Q13510,Q14738,Q06136,O14678,Q9NP80,P05091,Q96CU9,P16615,P53985,P06865,P06280,Q15907,Q99707,P98175,P21964,P08236,Q2TAA5,Q99797,O15269,Q10713,P08574,O15270,O15228,Q15427,Q9Y4P3,P10253,P07437,Q15067,Q9Y6M9,Q9NPL8,P31483,P61586,Q99519,Q96L58,Q13535,P08670,O96028,O75569,P22626,Q16625,P38159,P42345,Q96AY3,Q96RL7,P48651,P14854,P01889,P11117,Q4J6C6,Q96HY6,O60313,O60568,P61978,Q15120,Q8TB36,P10321,O15460,Q13315,P51571,O95202,O95831,O75306,Q9UPT5,P50402,P46977,P22830,P42695,Q96EY8,Q9NVI7,Q8N201,P04350,P42858,O75648,Q6NUQ1,O15360,O75845,Q9H7Z7,O43772,P23378,O00584,Q9BW92,Q9Y2Z2,Q8TAA9,Q12769,O76024,Q6PGP7,Q14376,Q9BT22,Q96PZ0,P27544,Q96MF7 235 +Metabolic proteins 0.2640971374563028 1.7904315326153144 0.0733845649088109 0.7822337343569212 0.1334264816523835 962 O75874,O15217,Q14197,Q6UX53,P52789,P11177,O14965,P48735,O95630,Q9UBX3,Q70HW3,P30154,O60512,O95168,Q13107,O43676,P50897,Q15392,Q16134,Q14849,P00403,P04062,O75844,P23786,P07602,P43490,Q99567,P16278,P30519,Q9Y619,O75964,Q9H2D1,Q8TB61,Q9Y680,Q9UHG3,P09601,O60725,P17900,P03886,Q9UDW1,P54646,P00374,Q9UL01,Q86UY6,O95470,P54802,Q15800,Q8NCC3,Q9BTX1,Q9NPH0,Q8NBX0,P46934,Q969T7,P51648,O15118,Q13126,Q8IV08,O14929,Q14534,Q96G23,Q7LGA3,P24539,Q15165,P07099,Q06520,Q13423,O60502,O14949,Q9BQT8,Q9P0J0,P49902,P08183,O14773,Q8N2A8,P37268,P53701,Q86Y39,Q8WTV0,Q8N4A0,P67812,Q9Y487,Q9NWM8,Q96N66,Q15043,O43292,Q9NVH6,O60684,Q9BTY2,P15586,Q9H7B4,Q16850,Q96PU5,Q00325,P12235,Q93050,Q14739,P10619,P52429,O60476,P16435,Q8TBX8,O00411,Q13510,P35610,Q96K76,Q06136,Q53GQ0,Q9NP80,P05091,P16615,P53985,P06865,P06280,Q6P2P2,Q96K12,Q99707,P21964,P08236,O15254,Q2TAA5,O15269,Q10713,Q9P035,P08574,O15270,Q9BRR6,Q9BWD1,Q9H773,O15228,P10253,P13674,Q15067,Q9Y6M9,Q15118,Q99519,Q96L58,Q13535,P13073,O96028,O95302,Q9BYT8,Q15418,Q96AY3,P48651,Q9NUQ2,P48729,P14854,P04844,P11117,O60568,O76062,P21127,P20020,P51970,Q15120,O14734,O15460,Q13315,P51571,P30825,Q7Z2T5,O75306,P12236,O14975,Q92820,P46977,P22830,Q96EY8,P40937,O75648,Q86YN1,Q709F0,Q10472,O14744,O75845,Q9H7Z7,O43772,P23378,O43865,Q9UG56,Q12769,Q14376,Q15904,Q8N4Q0,Q9BT22,P27544,P53350,Q8NF37 188 +Disease related genes 0.2446697202558109 1.2756903985141024 0.2020649840119359 0.9890516045635698 0.2886642628741942 1119 O75874,P11177,P61916,P48735,O95630,Q9H061,P51798,Q7KZN9,Q92974,Q70HW3,Q9Y2R0,O43676,P50897,Q15392,Q16134,Q8N511,Q99720,Q9H0U3,P00403,P04062,Q9UGP8,O75844,P23786,Q32P28,Q15154,Q15022,Q12768,P07602,Q99567,P16278,Q9Y619,P49770,Q9H2D1,P28288,P09601,Q14108,O75477,Q16637,Q96D71,Q6NUK1,P17900,P42892,P23246,P03886,P43243,Q99959,P00374,Q9NXE4,Q9UL01,Q6DKK2,P51114,Q99523,O95470,P54802,Q15800,O75718,Q6P4Q7,Q8N1F7,Q92542,Q00839,P05023,O60762,O14936,Q8NFH4,O75503,P51648,Q9Y366,O14979,O15118,Q9UBM7,Q8TCJ2,Q13126,Q8NAT1,Q5XKP0,Q13885,Q9UHX1,Q9Y584,Q8IV08,Q03154,P51812,Q16836,Q9H490,Q9Y320,Q9NZ01,Q8TD16,Q5JPH6,P38435,P36551,P78318,P07099,Q8WVX9,Q13423,Q9Y4W2,Q9UM00,Q9UBN7,Q5SRE5,O14949,P61313,Q9BQT8,Q9P0J0,Q86XL3,P49902,P08183,O14773,Q4KMQ2,P35658,Q5VV42,P37268,P53701,Q86Y39,Q9H9P8,Q96J02,Q96GX5,Q8IZP0,P11166,Q9Y487,Q5T2R2,P00367,P49257,P78527,Q9NWM8,Q9UJS0,Q9NWS8,Q96EK5,Q96DH6,Q9NR28,Q96N66,Q9Y287,P21912,Q15043,O75746,O43292,P51572,P55795,Q9NVH6,O95684,Q06787,P05067,P15586,Q96PU5,Q03519,Q00325,P12235,Q03518,Q14739,Q92804,Q96PC5,P10619,P52429,P16435,Q6P4A7,Q6ZXV5,P35637,P13473,P04439,Q13510,O76031,Q14738,Q06136,O14678,Q9NP80,Q96CU9,Q8TBA6,P16615,P53985,P06865,P06280,Q15907,Q01844,Q99707,P98175,P21964,P08236,Q2TAA5,Q99797,O15269,O43572,Q10713,P08574,O15270,O15228,Q15427,Q9Y4P3,P10253,P07437,Q15067,Q9Y6M9,Q9NPL8,P31483,P61586,Q99519,Q96L58,Q13535,P13073,P08670,O96028,O75569,P22626,Q16625,P38159,P42345,Q96AY3,Q96RL7,P48651,P14854,P01889,P11117,Q4J6C6,Q96HY6,Q96A33,O60313,O60568,P61978,Q15120,Q8TB36,P10321,O15460,Q13315,P51571,Q6DKJ4,O95831,O75306,P50402,P46977,P22830,P42695,Q92733,Q96EY8,Q9NVI7,Q8N201,P04350,P42858,O75648,Q6NUQ1,O15360,O75845,O43772,Q7L592,P23378,O00584,Q9BW92,Q9Y2Z2,Q8TAA9,Q12769,O76024,Q6PGP7,Q14376,Q15904,Q5HYI8,Q9BT22,Q96PZ0,P27544,P53350,Q96MF7,Q8N5M9 255 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..be403d7f6ff6fd60e93ee386efe66bdccf502fb5 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD11", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACY1", "ADAR", "ADD1", "ADD2", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT4", "AGPAT5", "AGPS", "AGTPBP1", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG11", "ALG2", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APIP", "APMAP", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAP1", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL15", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARL8A", "ARL8B", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMC9", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARSA", "ARVCF", "AS3MT", "ASAH1", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATM", "ATP13A1", "ATP1A1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B4GALT3", "B4GAT1", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BARD1", "BAX", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT1", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BDH2", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLOC1S1", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BRMS1L", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C19orf25", "C19orf70", "C1QBP", "C1orf122", "C1orf123", "C1orf35", "C21orf59", "C2CD2L", "C2CD5", "C2orf49", "C3orf58", "C5orf51", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARHSP1", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CASP7", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC115", "CCDC124", "CCDC127", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CDC16", "CDC23", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC42BPB", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPU", "CENPV", "CEP170", "CEP250", "CEP290", "CEP44", "CEP55", "CEP97", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK1", "CHEK2", "CHERP", "CHID1", "CHM", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHTF18", "CHTF8", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLN5", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMBL", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG5", "COG7", "COG8", "COIL", "COLGALT1", "COMMD2", "COMMD7", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6B1", "COX6C", "COX7C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF15", "DCAF16", "DCAF7", "DCAKD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND5B", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIMT1", "DIP2A", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DR1", "DRG1", "DRG2", "DSC2", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTL", "DTYMK", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD2", "EFL1", "EFR3A", "EFTUD2", "EHD1", "EHD4", "EHHADH", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELP1", "ELP2", "ELP3", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERP29", "ERP44", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETHE1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXTL3", "EYA4", "EZR", "FABP5", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM105A", "FAM114A2", "FAM120A", "FAM120B", "FAM126A", "FAM129B", "FAM136A", "FAM162A", "FAM208A", "FAM20B", "FAM213A", "FAM49B", "FAM50A", "FAM83D", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXL18", "FBXO22", "FCGRT", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOCAD", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FSD1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "FYCO1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNT1", "GALNT2", "GALNT4", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GGCT", "GGCX", "GGH", "GHDC", "GHITM", "GID8", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNB1L", "GNE", "GNG5", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNPNAT1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOSR1", "GOT1", "GOT2", "GPAA1", "GPATCH8", "GPD1L", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTA4", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP6", "GTPBP8", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAGH", "HARS2", "HAT1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HELZ", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HP1BP3", "HPF1", "HPRT1", "HPS5", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HTT", "HUS1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS14", "INTS3", "INTS4", "INTS6", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "IRS4", "ISCA2", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGA6", "ITGAV", "ITGB1", "ITM2B", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KATNB1", "KCTD10", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KDSR", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA1211", "KIAA1468", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNSTRN", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LNPK", "LONP1", "LPCAT1", "LPCAT4", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC14", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRFIP1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM6", "LSM7", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LZTFL1", "M6PR", "MACF1", "MAGED1", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAP4K4", "MAPK1", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED17", "MED21", "MED23", "MED24", "MED4", "MEPCE", "MESD", "METAP2", "METTL13", "METTL25", "METTL7B", "MFAP1", "MFGE8", "MFN1", "MFSD10", "MFSD3", "MFSD5", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MINPP1", "MIPEP", "MKI67", "MLEC", "MMAB", "MMACHC", "MMS19", "MOCS1", "MOCS3", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPDZ", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17L2", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFR", "MTIF2", "MTMR2", "MTMR6", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "ND1", "NDC1", "NDC80", "NDRG1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEDD4L", "NEFL", "NEFM", "NEK9", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NET1", "NEU1", "NF1", "NFATC2IP", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRM", "NRP1", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSMCE3", "NSRP1", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALD1", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PARS2", "PATL1", "PAWR", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PCYOX1", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXP", "PEBP1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHLDB2", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGK", "PIGS", "PIGT", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R2", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLCG2", "PLD3", "PLD6", "PLEC", "PLEKHA5", "PLEKHA7", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA4", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "POMP", "PON2", "POP1", "POR", "POU2F1", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPFIBP1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRMT9", "PRPF18", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRUNE1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB36", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RABEP1", "RABGAP1", "RABGGTA", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAF1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RASAL2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBBP9", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDX", "RECQL", "REEP5", "REL", "RELA", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RGS10", "RHBDD2", "RHEB", "RHOA", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIOX2", "RIPK1", "RMC1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASEH2B", "RNASET2", "RNF2", "RNF20", "RNF213", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RP2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SACS", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL1", "SCYL2", "SDAD1", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFMBT1", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGK3", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIGMAR1", "SIN3A", "SIPA1", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A9", "SLC16A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A2", "SLC27A4", "SLC29A1", "SLC2A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLMAP", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SMYD4", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNTB2", "SNU13", "SNW1", "SNX1", "SNX12", "SNX14", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRA1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPK2", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TAPBP", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP1", "TCP11L1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB1M", "TFB2M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLN1", "TM7SF2", "TM9SF3", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM126A", "TMEM160", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM33", "TMEM43", "TMEM87A", "TMEM97", "TMLHE", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TNRC6A", "TOE1", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TONSL", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPMT", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC13", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC28", "TTC37", "TTC38", "TTC4", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBE4B", "UBL5", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR2", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "ULK3", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP24", "USP28", "USP32", "USP34", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMP1", "VPS13A", "VPS13C", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "WAPL", "WARS", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR35", "WDR36", "WDR4", "WDR41", "WDR43", "WDR46", "WDR47", "WDR48", "WDR5", "WDR6", "WDR61", "WDR62", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIPI2", "WLS", "WNK1", "WRAP53", "WRAP73", "WTAP", "WWP2", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO6", "XPO7", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YKT6", "YLPM1", "YME1L1", "YPEL5", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB8", "ABCD3", "ABCD4", "ABI1", "ACAD11", "ACAT2", "ACOT8", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACY1", "ADPGK", "AGPAT5", "AHCYL1", "AIFM1", "AKAP10", "ALDH2", "ALDH3A2", "ALG1", "ALG11", "ANKLE2", "ANO6", "ANXA1", "APOL2", "APOO", "APP", "ARHGEF2", "ASAH1", "ASNA1", "ATAD3A", "ATG9A", "ATL2", "ATM", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP5F1", "ATP5L", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATR", "AURKA", "B3GALT6", "B4GALT3", "BCAP31", "BCL2L13", "BICD2", "BRI3BP", "BSG", "C19orf70", "C1QBP", "CASK", "CCDC47", "CCNB2", "CD109", "CDC37", "CDK11B", "CDKAL1", "CERS1", "CERS2", "CISD1", "CKAP4", "CLCN7", "CLN5", "CLPTM1", "CLPTM1L", "CLPX", "CNNM3", "CNNM4", "COA3", "COMT", "COX15", "COX2", "COX4I1", "COX6B1", "CPD", "CPOX", "CPT2", "CRTAP", "CSNK1A1", "CTSA", "CUTA", "CXADR", "CYB5B", "CYB5D2", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DCAKD", "DCP1A", "DCTPP1", "DDRGK1", "DERL1", "DGKE", "DHCR24", "DHCR7", "DHFR", "DHRS7B", "DHX36", "DIABLO", "DNAJC1", "DNAJC11", "DNAJC16", "DOLPP1", "DPM1", "DSE", "EARS2", "ECE1", "EFCAB14", "EIF2B2", "EIF3L", "EMC7", "EMD", "ENDOD1", "EPDR1", "EPHX1", "ERAP1", "ERAP2", "ERGIC3", "ERLIN1", "ESPL1", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "FADS2", "FAM105A", "FAM162A", "FAM8A1", "FANCA", "FAR1", "FAR2", "FCGRT", "FDFT1", "FECH", "FGFR1OP", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "FMR1", "FOXRED1", "FUCA2", "FUS", "FXR1", "GAA", "GALE", "GALNT1", "GALNT4", "GBA", "GDAP1", "GGCX", "GGH", "GLA", "GLB1", "GLDC", "GLG1", "GLUD1", "GM2A", "GNPAT", "GNS", "GOLGA5", "GOLIM4", "GOSR1", "GPAA1", "GPR107", "GPR108", "GPR180", "GSTA4", "GUSB", "HACD3", "HADH", "HAT1", "HCCS", "HDAC6", "HEXA", "HK2", "HLA-A", "HLA-B", "HLA-C", "HM13", "HMOX1", "HMOX2", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HS2ST1", "HSD17B12", "HSDL1", "HTT", "ICMT", "IDH1", "IDH2", "IFT52", "IGBP1", "IKBIP", "ILVBL", "IMMT", "INTS1", "IPO8", "ITCH", "ITM2B", "ITM2C", "JAGN1", "KDELR1", "KDELR3", "KDSR", "KIAA0100", "KIAA0319L", "KIF5B", "KIFBP", "KPNA1", "KPNA6", "L2HGDH", "LAMP1", "LAMP2", "LAS1L", "LBR", "LETM1", "LGALS3BP", "LMAN1", "LMF2", "LNPEP", "LPCAT1", "MAGT1", "MAN1A2", "MAN2A1", "MASTL", "MATR3", "MBOAT7", "MCL1", "MED24", "METTL7B", "MFGE8", "MFSD10", "MFSD3", "MGEA5", "MIA2", "MICU2", "MIEF1", "MIGA1", "MIPEP", "MMAB", "MPV17L2", "MRPL58", "MSI2", "MSMO1", "MTAP", "MTCH1", "MTCH2", "MTDH", "MTFP1", "MTO1", "MTOR", "MTR", "MTX1", "NAA40", "NAGLU", "NAMPT", "NCAPD3", "NCKAP1", "NCSTN", "ND1", "NDC1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB9", "NDUFS2", "NEDD4", "NEDD4L", "NEU1", "NLN", "NNT", "NPC1", "NPC2", "NRM", "NRP1", "NSD2", "NSMCE2", "NT5C2", "NT5C3B", "NUCB1", "NUCB2", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP54", "NUP88", "NUP93", "NXN", "OCIAD1", "OCLN", "OPA1", "ORC3", "OS9", "OSBPL8", "OXA1L", "P3H1", "P4HA1", "P4HA2", "PCM1", "PCYOX1", "PDHB", "PDK1", "PDK3", "PDSS1", "PEX19", "PGRMC1", "PGRMC2", "PIGU", "PIP4K2C", "PISD", "PKP2", "PLA2G15", "PLD3", "PLD6", "PLK1", "PLOD3", "PMPCA", "PNPLA8", "POLRMT", "POMGNT2", "PON2", "POR", "PPP2R1B", "PPP2R5D", "PPT1", "PRCC", "PREB", "PREPL", "PRKAA2", "PRKDC", "PRKRA", "PRMT5", "PRMT9", "PSAP", "PSMB2", "PTDSS1", "PTGES2", "PUF60", "PUS7", "PXMP2", "QSOX2", "RAB11B", "RABL3", "RBM10", "RBMX", "REPS1", "RETSAT", "RFC5", "RHBDD2", "RHOA", "RINT1", "RMND1", "RNASET2", "RPL15", "RPN2", "RPS6KA1", "RPS6KA3", "RTN3", "RTN4", "SAMM50", "SC5D", "SCAMP2", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCPEP1", "SDCBP", "SDF4", "SDHB", "SEC11A", "SEC63", "SEL1L", "SF3B4", "SFPQ", "SFXN2", "SFXN4", "SGPL1", "SIGMAR1", "SLC12A2", "SLC12A9", "SLC16A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A6", "SLC27A2", "SLC2A1", "SLC35B2", "SLC39A14", "SLC4A7", "SLC7A1", "SLMAP", "SMIM12", "SMN1*", "SMPD4", "SMYD3", "SMYD4", "SNX27", "SOAT1", "SORT1", "SPNS1", "SPTLC1", "SPTLC2", "SQLE", "SRPRB", "SSR1", "SSR4", "STAMBP", "STARD3", "STT3A", "STT3B", "STX18", "STX3", "STX5", "SULT2A1", "SUN1", "SUN2", "SURF4", "SUZ12", "SYNJ2BP", "TAF15", "TAP1", "TAP2", "TARS2", "TBL2", "TDRKH", "TECR", "THOC1", "TIA1", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMMDC1", "TM7SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED7", "TMEM126A", "TMEM160", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM209", "TMEM33", "TMEM87A", "TMEM97", "TMLHE", "TMTC3", "TMX2", "TMX4", "TNPO1", "TOMM22", "TPBG", "TPP1", "TRABD", "TRAM1", "TRMT1L", "TRMU", "TSPAN3", "TSPAN6", "TTC19", "TTC37", "TTYH3", "TUBB", "TUBB2A", "TUBB4A", "UQCR10", "UQCRQ", "USP4", "USP47", "VANGL1", "VDAC2", "VIM", "VKORC1L1", "VMP1", "VPS13A", "WASHC5", "WFS1", "WLS", "XPO4", "XPO5", "ZADH2", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/idx2term.json b/protein_atlas_subcellular_location_all/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..cec18f1df6edff1b2bbf1cd1c2b179650942d27b --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Endoplasmic reticulum", "1": "Mitochondria", "2": "Golgi apparatus", "3": "Vesicles", "4": "Nuclear membrane"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/advanced/plot_0.png b/protein_atlas_subcellular_location_all/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d26549d3e28b0584a4462332619ccecaa7c1cb12 --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2a09aefa532111db8e0ee4f686c0299a40fd4bd31d9b5f5a1c586b9d8fdda335 +size 207470 diff --git a/protein_atlas_subcellular_location_all/advanced/plot_1.png b/protein_atlas_subcellular_location_all/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..f28ff66a10ce194236f01379f74c8b080a75e31b --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b3e869f5bf0c25757419f7b53983e69f78fd038b9180d32848355c42de9a3bea +size 213254 diff --git a/protein_atlas_subcellular_location_all/advanced/plot_2.png b/protein_atlas_subcellular_location_all/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..5dfda73e62bb28ee7f82e0086627eff65fa73c6c --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a62f86063dd48a008c17c9d1aee412d392de02a8fc2f638937eaa87a942f7964 +size 208349 diff --git a/protein_atlas_subcellular_location_all/advanced/plot_3.png b/protein_atlas_subcellular_location_all/advanced/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..685b40cb56f016d772e3d562eefea0d294a3fae4 --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c3ca96189bc34a95fd458582d8e18a890303749becd2a60abc60eab0f8cc41a6 +size 214523 diff --git a/protein_atlas_subcellular_location_all/advanced/plot_4.png b/protein_atlas_subcellular_location_all/advanced/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..cd6281560cfa82116405ba32b770671ee8a1ea26 --- /dev/null +++ b/protein_atlas_subcellular_location_all/advanced/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4611ebf267473f1972784618b2fa8c6b2d58f8006c73d2dcbfa40399b5394aa5 +size 194156 diff --git a/protein_atlas_subcellular_location_all/basic/idx2term.json b/protein_atlas_subcellular_location_all/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..84085d6e6bb3fa435e98b5e0981d0bb9270dc466 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Endoplasmic reticulum", "1": "Mitochondria", "2": "Golgi apparatus", "3": "Vesicles", "4": "Nuclear membrane", "5": "Centriolar satellite", "6": "Peroxisomes", "7": "Cell Junctions", "8": "Intermediate filaments", "9": "Focal adhesion sites", "10": "Centrosome"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/basic/plot_0.png b/protein_atlas_subcellular_location_all/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..d194eaa33806fede0b994a745d8599a984330f8f --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:13558757e23dee46dae9b2a614c916be91af9fb91691bf10654eed9fd6086197 +size 146884 diff --git a/protein_atlas_subcellular_location_all/basic/plot_1.png b/protein_atlas_subcellular_location_all/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..82e7246dd3f66f0affa5af4546546b75746c603e --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c208173701f859f982d6bbcbd035bd50040c6101804a203fe6c97e9a3c96c925 +size 138394 diff --git a/protein_atlas_subcellular_location_all/basic/plot_10.png b/protein_atlas_subcellular_location_all/basic/plot_10.png new file mode 100644 index 0000000000000000000000000000000000000000..8da14fd2509d70ceb1dc519f35c93b0c9d1b951f --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_10.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:79bee7d8bb40c4e09e9ae50aa3929da2090c12a0ebcc825e2e0527553a53e9fc +size 144515 diff --git a/protein_atlas_subcellular_location_all/basic/plot_2.png b/protein_atlas_subcellular_location_all/basic/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..00f190e40585ed76e47a304085e81a6aa32dd0b7 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:00908ac53f9237dc1abd8a3270149fb55e8210fe0341ed2988c99010076412ff +size 145144 diff --git a/protein_atlas_subcellular_location_all/basic/plot_3.png b/protein_atlas_subcellular_location_all/basic/plot_3.png new file mode 100644 index 0000000000000000000000000000000000000000..58ca086f9c62b008ac07127860dfe39dc9eed50f --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_3.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c39198dfe30a6937882ad501e8385eef1324e240ca881c78aeffa5715bda0c66 +size 139664 diff --git a/protein_atlas_subcellular_location_all/basic/plot_4.png b/protein_atlas_subcellular_location_all/basic/plot_4.png new file mode 100644 index 0000000000000000000000000000000000000000..7fdcb312adf69b89705ace7bd03b01b5ab4ede6a --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_4.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:ba86c017abd38e423ea1ea18d8e5615f20f159c8979c1933d33dfaaf798d8dc3 +size 140607 diff --git a/protein_atlas_subcellular_location_all/basic/plot_5.png b/protein_atlas_subcellular_location_all/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..7186ed8ef2b625dd8de2c61b1384de2077159bdd --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:82b64ec993afc68a5760a673cbea6946a0be1e1c3c300744ad37e93ec4a7ca51 +size 141219 diff --git a/protein_atlas_subcellular_location_all/basic/plot_6.png b/protein_atlas_subcellular_location_all/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..86281521fb47fb1be90dc91f0410b36cbcd39071 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:59b03d90ba1fd67426e44a973ff595cdeb49823e478af0f8c71b2fc3d13e92f4 +size 142724 diff --git a/protein_atlas_subcellular_location_all/basic/plot_7.png b/protein_atlas_subcellular_location_all/basic/plot_7.png new file mode 100644 index 0000000000000000000000000000000000000000..ac0c0ba081ce146b14c05154f56a97765ce468b7 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_7.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5472e263e4d98684119a66188b81b40f3b26a5730c45859e07f53dee6bb38a5d +size 146610 diff --git a/protein_atlas_subcellular_location_all/basic/plot_8.png b/protein_atlas_subcellular_location_all/basic/plot_8.png new file mode 100644 index 0000000000000000000000000000000000000000..a6c6c8b9794fadc559cc28a7d23296af604e017c --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_8.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:2f6722e1073afa8cfc756487a9ff8d99ad110f3877684ab7f40b2c32815f7830 +size 146714 diff --git a/protein_atlas_subcellular_location_all/basic/plot_9.png b/protein_atlas_subcellular_location_all/basic/plot_9.png new file mode 100644 index 0000000000000000000000000000000000000000..885e6ad4ff2a08f391e76610ec85ea7c426864c8 --- /dev/null +++ b/protein_atlas_subcellular_location_all/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5e6e8b938dd5005e08caa36dddc2bb97cd5cdb0797d91d66d340ce4ccf94c94f +size 150593 diff --git a/protein_atlas_subcellular_location_all/consensus.joblib b/protein_atlas_subcellular_location_all/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7ee766b5b68d19a12eedb045c02a2306a845dfff --- /dev/null +++ b/protein_atlas_subcellular_location_all/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a376478a9601f29665317ec5c4a95c1faca07972e264c1e6be245d3a3555c319 +size 88270 diff --git a/protein_atlas_subcellular_location_all/df_merge.tsv b/protein_atlas_subcellular_location_all/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..dad5ed176d0d3772fdb982c0f951d5f154f71a54 --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,6 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Endoplasmic reticulum 84 204 5.149781833781697 2.607896274187553e-07 55.37621359223301 196.57766990291265 1.2201083743235763 0.4903523338807414 18.868778270733547 13.264167600850914 1.8573715045605257 0.4308007257692164 1.0450483370011334e-08 0.0910053419471295 0.007163094589623 2.7072482462967983e-08 2.660092505404072e-16 +Mitochondria 137 426 4.239712803440796 2.238059391124203e-05 110.1747572815534 400.5485436893204 0.4320244196044261 0.5794127039570083 42.49664228528663 36.15232166758906 2.0400795827803786 0.4211568684384254 5.423687508984159e-07 0.0007762707630251 0.000240624515426 8.638078806893441e-07 1.121334662005284e-11 +Golgi apparatus 53 183 4.121691384256651 3.761008299840718e-05 46.45873786407767 176.03155339805826 1.3643789213018729 0.3972771337532677 14.511319530749702 26.453870355965975 1.6568954592349954 0.4161874156663988 7.762672190352634e-05 0.0139110470518646 0.0002031401898823 0.0003117824975691 0.0029596289985125 +Vesicles 64 328 3.5597495010071323 0.0003712087116858 63.69174757281554 303.19174757281553 0.3021616120018026 0.6308308858815788 16.21576692438533 35.60761931464484 1.2670437076534344 0.3993041904676221 0.0139958038702059 0.0271170180029465 0.0215933264294523 0.0223954952796336 0.0684518274911556 +Nuclear membrane 18 67 2.118735918528136 0.0341127910234897 16.817961165048544 62.713592233009706 0.5402747034161678 0.5293388535672136 7.339768502370818 5.865441797870943 1.2287110387783358 0.3803813474041967 0.069322661564314 1.0 0.5359507558141487 0.0777469554316842 0.0601725009548874 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..05af60eae1ac15f8ed14733eb4ab95fb81462419 --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3430, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 161.33333333333334 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..2b01d4a6b1b1ce1cf9bd4fc921c59ccce91fb80d --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C004/C004_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..588b77390fbccae46fbc60492b52178e17dc6a0b --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,12 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Endoplasmic reticulum 0.4764697797146811 5.149781833781697 2.607896274187553e-07 8.606021795019376e-06 4.303028852425961e-06 204 O43169,Q8N0U8,Q14849,Q9UGP8,P43307,Q9Y680,Q8NHH9,O75477,O95470,Q15800,P46776,Q13438,O43731,O15260,P51648,Q9UBM7,Q8TCJ2,Q14BN4,Q8IV08,Q96G23,Q9NZ01,Q8WUJ1,Q9P2W9,O95197,Q14257,O96005,O00767,O00264,Q9UM00,Q9HCU5,P46782,Q86XL3,P37268,P49257,Q96GC9,Q15043,O43292,P51572,Q96CN7,Q15041,Q16850,Q03519,Q03518,Q92791,P27824,Q96PC5,Q9UBS4,Q6UW68,P27635,Q9Y3U8,P35610,P62753,Q86UE4,Q99442,P21964,Q8TCT9,O15269,Q9P035,Q5BJF2,P14625,Q96KA5,P13674,Q96KC8,O43852,Q9H3G5,Q9NQC3,P48651,Q9BUN8,P04844,Q96HY6,Q96A33,O76062,P67809,O15460,P51571,P50402,Q5T9L3,Q70UQ0,O75845,Q5HYI8,Q9BT22,P62841,P27544,Q8NF37 84 +Mitochondria 0.3679500166078879 4.239712803440796 2.238059391124203e-05 0.0007382951897843 0.0002461865330236 426 Q99623,Q14197,P52789,P11177,Q9NS69,P48735,Q69YU5,Q9UBX3,Q7KZN9,P45880,Q70HW3,O95168,Q9Y2R0,O60830,P23786,Q9UDX5,Q96EX1,O75964,Q9H2D1,P43304,Q9Y2S7,Q9Y5J7,Q13505,O43615,Q6NUK1,Q9H2U1,Q3SXM5,Q9H4I3,P00374,Q9NWU1,Q99595,Q6DKK2,Q5JRX3,Q9NVH1,Q96A26,Q9BUR5,Q8N4H5,Q8WY22,Q5XKP0,Q07820,Q16836,Q9Y5L4,Q7LGA3,Q8NAN2,Q5JPH6,P36551,P24539,Q9Y6C9,Q13423,O14949,Q9P0J0,Q9H9P8,Q8TAE8,P53701,Q86Y39,P06576,O75438,P00367,Q9BXK5,P82933,Q9UJS0,Q15070,Q9NWS8,Q9NR28,P21912,Q6UXV4,O43292,P82663,Q9NVH6,Q9BYC9,Q96C01,O14925,Q68CZ6,Q9NX40,Q9NX63,Q00325,P12235,Q9NSK0,P56385,Q9NUJ1,Q9P032,Q6P4A7,Q07021,P21953,P57105,P05141,Q9UHQ9,Q8IWA4,Q96CX2,O00411,O76031,Q9Y394,Q4VC31,Q5T9A4,Q96CU9,Q9Y512,Q99797,Q10713,Q8N6Q8,P08574,Q9Y277,P13674,Q14168,Q9Y6M9,Q9NPL8,P13073,O95302,Q8IYU8,Q9BYT8,Q96AY3,Q9NUQ2,P14854,Q8N3Z3,O60313,P51970,Q15120,Q8TB36,O14734,Q9NZ45,O95202,Q96NB2,Q7Z4V5,O95831,O75306,P12236,Q9H2W6,Q96EY8,Q9NVI7,O75648,Q9NQ50,Q9H7Z7,O43772,P23378,Q16891,Q9NQG6,Q7Z7H8,Q9NUT2 137 +Golgi apparatus 0.4301380770076336 4.121691384256651 3.761008299840718e-05 0.0012403861634404 0.0003102831847368 183 P80303,P24390,Q9NP80,Q9UBU6,Q8TBA6,Q92896,O60512,Q8IYR2,P50897,Q6P179,Q96K12,Q9NXU5,O00461,Q13190,Q16706,Q6ZRP7,Q9HB40,Q96SU4,P16278,Q8N4A0,P67812,Q9H2V7,Q9H8H2,Q9NWM8,A1L0T0,P09601,Q9Y287,P22059,Q15043,Q5VW38,Q6NUQ1,O15127,P54646,P05067,Q9BRK5,Q13535,Q8NBN3,O95302,Q9HD45,Q93050,Q8IZA0,Q9UG56,O15260,Q5BKZ1,O60476,Q9NPR9,Q14376,Q8N4Q0,O75071,P25398,P04439,Q02818,O60637 53 +Vesicles 0.3410710546395426 3.5597495010071323 0.0003712087116858 0.0121774095511774 0.0024499774971265 328 Q96K76,P24390,Q9NRY5,Q92564,P67809,O14734,O15460,Q13315,P06865,P35613,Q8IYR2,P50897,Q15907,Q8TAF3,Q14849,P21964,P08236,Q9NUD5,Q32P28,Q9HD20,Q96ES6,P07602,Q8WTV0,P16278,P30519,Q13595,Q9H2V7,Q9Y487,Q13277,Q9H8H2,A1L0T0,Q8TB61,P10253,P13674,Q9Y287,O60506,P17900,Q3SXM5,O15127,Q96L92,P05067,P42785,Q99519,O95302,Q9HD45,Q8NCC3,Q92791,Q93050,Q8NBX0,P42345,P10619,Q5BKZ1,P16435,Q6P4A7,Q9NPR9,P13473,O15118,Q86V85,Q96JB5,Q96SK2,Q9Y2G8,Q14534,O76062,O75153 64 +Nuclear membrane 0.3988798872210774 2.118735918528136 0.0341127910234897 0.6818941251579704 0.1407152629718951 67 O15260,O00560,Q9H1E5,Q13277,P67812,Q9NXE4,Q9UH99,O94919,P50402,O95168,Q9BTX1,O94901,Q96SK2,O75976,Q8IXM6,Q96G23,Q14739,Q14728 18 +Centriolar satellite 0.4204767044398045 1.6479575877519848 0.0993613747145401 0.9683649330548249 0.3207794353286801 35 Q15154,P33176,O43169,Q13045,Q96QE3,Q86UY6,Q15907,P41208,Q03518,Q9UBK9 10 +Peroxisomes 0.4104755199061122 0.567249788874501 0.5705444854831332 0.9999999999992304 0.877247736782773 13 O43808,Q8WVX9,P28288,O15254,Q15067 5 +Cell Junctions 0.2702942653159504 0.3875567300878555 0.6983440952299032 1.0 0.877247736782773 57 Q6IAN0,P78310,P43490,Q8IZP0,Q6UW02,Q99959,Q9H2W6,Q99519,P53985,Q9NXU5,Q16625,Q9Y3A4,O43657 13 +Intermediate filaments 0.2700414289606344 0.2565865713567956 0.7974979425297937 1.0 0.877247736782773 38 Q3SXM5,Q16352,Q86YN1,P07197,P08670,O75718,Q96K76 7 +Focal adhesion sites 0.2752560882193205 0.2073878182529458 0.8357069954276033 1.0 0.8896235757777712 31 P08183,Q969Q5,Q9Y487,O60888,Q9Y6M7 5 +Centrosome 0.2355376740431498 0.1258418022829211 0.899857151343036 1.0 0.927977687322506 76 Q2T9J0,Q96DB5,O43292,P52789,Q9BU23,O14965,O95684,Q69YU5,Q9BRR6,Q9Y2W6,Q96LJ7,Q9UJW0 12 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ae5f9d48b41ef3a506d3c278dcbad3dab31b272b --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAGAB", "AAR2", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABAT", "ABCB1", "ABCB7", "ABCB8", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD14B", "ABHD6", "ABI1", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAP2", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN2", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ADAR", "ADD1", "ADD2", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT4", "AGPAT5", "AGPS", "AGTPBP1", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK4", "AK6", "AKAP1", "AKAP10", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKAP9", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1S1", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG2", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANKRD13A", "ANKRD17", "ANKS1A", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA4", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APIP", "APMAP", "APOO", "APOOL", "APP", "APRT", "AQR", "ARAP1", "ARCN1", "ARF6", "ARFGAP1", "ARFGAP2", "ARFGAP3", "ARFIP1", "ARG2", "ARHGAP1", "ARHGAP17", "ARHGAP18", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL15", "ARL2", "ARL3", "ARL6IP1", "ARL6IP5", "ARMC1", "ARMC10", "ARMC6", "ARMC8", "ARMCX3", "ARMT1", "ARPC1A", "ARPC1B", "ARPC2", "ARPC3", "ARRB2", "ARSA", "ARVCF", "AS3MT", "ASCC2", "ASCC3", "ASH2L", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ASRGL1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATE1", "ATG3", "ATG4B", "ATG7", "ATG9A", "ATIC", "ATL2", "ATL3", "ATM", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPIF1", "ATR", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GALT3", "BABAM1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BARD1", "BAZ1B", "BAZ2A", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDHB", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BDH2", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD4", "BRD8", "BRI3BP", "BRIX1", "BRMS1L", "BROX", "BSDC1", "BSG", "BTAF1", "BTF3", "BUB1", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf73", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "C2orf49", "C5orf51", "CAB39", "CACYBP", "CAD", "CALCOCO1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CARS2", "CASK", "CASP3", "CAST", "CBFB", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC115", "CCDC124", "CCDC127", "CCDC138", "CCDC22", "CCDC47", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCNB1", "CCNB2", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD3EAP", "CDC25C", "CDC27", "CDC37", "CDC40", "CDC42", "CDC5L", "CDC6", "CDC73", "CDCA2", "CDCA7L", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK12", "CDK13", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK5RAP3", "CDK9", "CDKN2AIP", "CEBPZ", "CECR2", "CELF1", "CELF2", "CENPB", "CENPF", "CENPU", "CENPV", "CEP170", "CEP250", "CEP290", "CEP55", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAC2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK1", "CHEK2", "CHID1", "CHM", "CHMP5", "CHMP7", "CHORDC1", "CHRAC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIT", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLIP1", "CLK3", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT10", "CNOT11", "CNOT3", "CNOT7", "CNP", "CNPY2", "COA3", "COA7", "COG5", "COG7", "COG8", "COIL", "COLGALT1", "COMMD7", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "CORO1B", "COTL1", "COX15", "COX4I1", "COX5B", "COX6B1", "COX6C", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CREBBP", "CRK", "CRKL", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDP1", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL4A", "CUL4B", "CUL5", "CUTA", "CUTC", "CWC22", "CWF19L1", "CXADR", "CXorf56", "CXorf57", "CYB5B", "CYB5D2", "CYB5R1", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF15", "DCAF16", "DCAF7", "DCAKD", "DCP1A", "DCP1B", "DCPS", "DCTD", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX31", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX55", "DDX56", "DDX6", "DEK", "DENND5B", "DENR", "DERA", "DERL1", "DERL2", "DFFA", "DGKE", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH2", "DIAPH3", "DICER1", "DIDO1", "DIMT1", "DIP2A", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAAF2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DNPH1", "DNTTIP2", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL3", "DPYSL5", "DR1", "DRG1", "DRG2", "DSC2", "DSG2", "DSP", "DST", "DTL", "DTYMK", "DUS2", "DUS3L", "DUSP12", "DUSP3", "DUSP9", "DUT", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "ECT2", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD2", "EFL1", "EFR3A", "EFTUD2", "EHD1", "EHD4", "EHMT1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELF2", "ELMO2", "ELMOD2", "ELOA", "ELP1", "ELP2", "ELP3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENSA", "ENY2", "EP400", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESPL1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETHE1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC6B", "EXOC7", "EXOC8", "EXOG", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EYA4", "EZR", "FABP5", "FAF1", "FAF2", "FAH", "FAHD1", "FAM105A", "FAM114A2", "FAM120A", "FAM120B", "FAM126A", "FAM129B", "FAM136A", "FAM162A", "FAM208A", "FAM20B", "FAM49B", "FAM50A", "FAM83D", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCA", "FANCD2", "FANCI", "FAR1", "FAR2", "FARP2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FBXL18", "FDFT1", "FDPS", "FDXR", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKBP9", "FKRP", "FLAD1", "FLCN", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FLYWCH1", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FNTB", "FOCAD", "FOXC1", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ1", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "FYCO1", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GADD45GIP1", "GAK", "GALE", "GALK1", "GALNT2", "GALNT4", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBE1", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN6", "GET4", "GFM1", "GFPT1", "GGA1", "GGA2", "GHITM", "GID8", "GIGYF2", "GINS1", "GINS2", "GINS3", "GINS4", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX5", "GLS", "GLT8D1", "GLUD1", "GLYR1", "GM2A", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNB1", "GNB1L", "GNE", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLPH3", "GOLT1B", "GORASP2", "GOT1", "GPAA1", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR180", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSPT1", "GSR", "GSS", "GSTCD", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E2", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GTPBP6", "GTPBP8", "GTSE1", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HARS2", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDAC6", "HDDC2", "HDGF", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HELZ", "HERC2", "HEXA", "HGH1", "HGS", "HIBCH", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPLL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HP1BP3", "HPF1", "HPRT1", "HPS5", "HS1BP3", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPB1", "HSPBP1", "HSPD1", "HSPH1", "HTATSF1", "HTT", "HUWE1", "IAH1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IFIT5", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INPPL1", "INTS1", "INTS11", "INTS12", "INTS14", "INTS3", "INTS4", "INTS6", "INTS7", "INTS8", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "IRF2BP1", "IRF2BPL", "IRGQ", "ISG20L2", "ISOC1", "IST1", "ISYNA1", "ITCH", "ITGAV", "ITGB1", "ITM2B", "ITPA", "ITPK1", "ITSN2", "IVD", "JAGN1", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KATNB1", "KCTD10", "KCTD12", "KDELC2", "KDELR1", "KDELR3", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDM5A", "KHDRBS1", "KHSRP", "KIAA0100", "KIAA0319L", "KIAA0368", "KIAA1211", "KIAA1468", "KIDINS220", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KLC4", "KMT2A", "KNSTRN", "KPNA1", "KPNA2", "KPNA3", "KPNA4", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMC1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LASP1", "LBR", "LCLAT1", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIN9", "LIPA", "LLPH", "LMAN1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPK", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRP1", "LRPAP1", "LRPPRC", "LRRC1", "LRRC14", "LRRC40", "LRRC41", "LRRC47", "LRRC57", "LRRC59", "LRRFIP1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM6", "LSM7", "LTA4H", "LTN1", "LTV1", "LUC7L", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYPLA2", "LZTFL1", "MACF1", "MAGED1", "MAGED2", "MAIP1", "MAK16", "MAN1A2", "MAN2A1", "MAN2B1", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP2K2", "MAP3K7", "MAP4", "MAPK1", "MAPK3", "MAPKAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD1", "MBD3", "MBOAT7", "MCCC1", "MCCC2", "MCL1", "MCM10", "MCM2", "MCM3", "MCM3AP", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCRS1", "MCTS1", "MCU", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED16", "MED17", "MED21", "MED23", "MED4", "MEPCE", "MESD", "METAP2", "METTL13", "METTL25", "METTL7B", "MFAP1", "MFGE8", "MFN1", "MFSD10", "MFSD3", "MGEA5", "MGME1", "MGST2", "MGST3", "MIA2", "MIA3", "MICAL3", "MICALL1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMACHC", "MMS19", "MOCS1", "MOGS", "MON2", "MORC2", "MORC3", "MORF4L1", "MOSPD2", "MOV10", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP7", "MPRIP", "MPST", "MRE11", "MRGBP", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL44", "MRPL46", "MRPL47", "MRPL50", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS7", "MRPS9", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTERF3", "MTFP1", "MTHFD1L", "MTHFD2", "MTHFR", "MTIF2", "MTMR2", "MTO1", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO6", "NAA15", "NAA25", "NAA35", "NAA40", "NAA50", "NADK2", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAM1", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCBP1", "NCBP2", "NCBP3", "NCDN", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCOR1", "NCSTN", "NDC1", "NDC80", "NDRG1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA8", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFB1", "NDUFB4", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NECTIN2", "NEDD4", "NEFL", "NEFM", "NELFCD", "NELFE", "NEMF", "NES", "NET1", "NEU1", "NF1", "NFATC2IP", "NHLRC2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME3", "NME7", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPAT", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRBP1", "NRDC", "NRM", "NSA2", "NSD2", "NSDHL", "NSF", "NSFL1C", "NSMCE2", "NSRP1", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD1", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT19", "NUDT21", "NUDT5", "NUDT9", "NUF2", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NVL", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD1", "OGFR", "OGT", "OLA1", "OPA1", "ORC3", "OS9", "OSBP", "OSBPL11", "OSBPL1A", "OSBPL2", "OSBPL8", "OSBPL9", "OTUB1", "OTUD7B", "OTULIN", "OXA1L", "OXCT1", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP1", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARD3", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PARS2", "PATL1", "PAWR", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCID2", "PCK2", "PCLAF", "PCM1", "PCMT1", "PCNA", "PCNP", "PCNT", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL", "PDCL3", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK3", "PDLIM1", "PDLIM3", "PDLIM5", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PEBP1", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM2L1", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHC2", "PHF2", "PHF3", "PHF6", "PHGDH", "PHIP", "PHLDB2", "PI4K2A", "PI4KA", "PIBF1", "PICALM", "PIGU", "PIH1D1", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PKP2", "PLA2G15", "PLAA", "PLCG1", "PLCG2", "PLD3", "PLEC", "PLEKHA5", "PLEKHA7", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PM20D2", "PMF1", "PMPCA", "PMPCB", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPLA8", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3B", "POLR3C", "POLR3E", "POLRMT", "POMP", "POP1", "POR", "POU2F1", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPFIBP1", "PPIB", "PPID", "PPIE", "PPIF", "PPIL2", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCA", "PRKCB", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRMT9", "PRPF18", "PRPF19", "PRPF3", "PRPF31", "PRPF38A", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS2", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PRUNE1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTBP2", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM1", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR2", "PYGB", "PYGL", "QARS", "QKI", "QRICH1", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB11B", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB36", "RAB3B", "RAB3GAP1", "RAB3GAP2", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RABEP1", "RABGAP1", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23A", "RAD23B", "RAD50", "RAE1", "RAF1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RANGRF", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RASAL2", "RAVER1", "RB1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBBP9", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM15B", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM47", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDX", "RECQL", "REEP5", "RELA", "REPS1", "RER1", "RETREG3", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFLNB", "RGS10", "RHBDD2", "RHOA", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOK1", "RIOK2", "RIOX2", "RIPK1", "RMC1", "RMDN1", "RMDN3", "RMND1", "RNASEH2A", "RNASEH2B", "RNF2", "RNF20", "RNF213", "RNF40", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RP2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RPUSD3", "RRAS2", "RRBP1", "RRM1", "RRM2", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSU1", "RTCB", "RTF1", "RTFDC1", "RTN3", "RTN4", "RTRAF", "RUFY1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "S100A13", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMD4B", "SAMHD1", "SAMM50", "SAP18", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SATB2", "SBDS", "SBNO1", "SC5D", "SCAF1", "SCAF11", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCML2", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCYL1", "SDAD1", "SDCBP", "SDE2", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC16A", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC24D", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETD2", "SETD3", "SETD7", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B5", "SF3B6", "SFMBT1", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGK3", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SH3RF1", "SHCBP1", "SHMT1", "SHMT2", "SHPRH", "SHTN1", "SIN3A", "SIPA1", "SIRT1", "SIRT2", "SKA3", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC16A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A20", "SLC25A22", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC35B2", "SLC35F2", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A7", "SLFN11", "SLIRP", "SLK", "SLMAP", "SLTM", "SLU7", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC6", "SMCHD1", "SMG5", "SMG8", "SMIM12", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SMYD4", "SNAPIN", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNTB2", "SNW1", "SNX1", "SNX14", "SNX2", "SNX27", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG5", "SPAG9", "SPART", "SPATA5", "SPATA5L1", "SPC24", "SPCS2", "SPDL1", "SPECC1", "SPECC1L", "SPEN", "SPNS1", "SPR", "SPRYD4", "SPRYD7", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SRA1", "SRBD1", "SRCAP", "SREK1", "SRI", "SRM", "SRP14", "SRP54", "SRP68", "SRPK1", "SRPK2", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "SSU72", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STAU2", "STIP1", "STK4", "STMN1", "STOML2", "STRAP", "STRIP1", "STRN", "STT3B", "STUB1", "STX12", "STX18", "STX3", "STX5", "STX7", "STX8", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP2", "SUGT1", "SULT2A1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT20H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAF6", "TAF6L", "TAGLN2", "TALDO1", "TAMM41", "TAOK1", "TAP1", "TAP2", "TARBP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL2", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF20", "TCOF1", "TCP11L1", "TDP2", "TDRKH", "TECR", "TEFM", "TELO2", "TENM3", "TERF2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFB2M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THNSL1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIA1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKFC", "TKT", "TLN1", "TM7SF2", "TM9SF3", "TMA16", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM126A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM87A", "TMEM97", "TMLHE", "TMOD3", "TMX1", "TMX2", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TNRC6A", "TOE1", "TOM1", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TONSL", "TOP1", "TOP2A", "TOP2B", "TOPBP1", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAF2", "TRAP1", "TRAPPC11", "TRAPPC13", "TRAPPC4", "TRAPPC5", "TRAPPC8", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM33", "TRIO", "TRIP12", "TRIP13", "TRIR", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TST", "TSTA3", "TTC1", "TTC19", "TTC27", "TTC28", "TTC37", "TTC38", "TTC4", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF2", "TWISTNB", "TXLNA", "TXLNG", "TXNDC5", "TXNDC9", "TXNL1", "TXNL4A", "TXNRD1", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2Q1", "UBE2S", "UBE2T", "UBE3A", "UBE3C", "UBE4A", "UBL7", "UBP1", "UBQLN4", "UBR1", "UBR2", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "URB1", "UROD", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP24", "USP28", "USP32", "USP34", "USP39", "USP4", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP3", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VASP", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13C", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VRK3", "WAPL", "WARS", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDCP", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR33", "WDR36", "WDR4", "WDR41", "WDR46", "WDR47", "WDR48", "WDR5", "WDR6", "WDR61", "WDR62", "WDR74", "WDR77", "WDR82", "WIPI2", "WLS", "WNK1", "WRAP53", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO6", "XPOT", "XRCC1", "XRCC4", "XRCC5", "XRCC6", "XRN1", "XRN2", "YARS", "YARS2", "YBX1", "YES1", "YKT6", "YLPM1", "YME1L1", "YPEL5", "YRDC", "YTHDC1", "YTHDC2", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H7A", "ZC3H7B", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFR", "ZFYVE16", "ZMAT2", "ZMYM2", "ZMYM3", "ZMYM4", "ZNF207", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZPR1", "ZRANB2", "ZW10", "ZYX"], "leading_proteins": ["ABCB1", "ABCB8", "ABCD3", "ABHD10", "ABI1", "ACOT8", "ACOX1", "ACOX3", "ADPGK", "AGPAT5", "AIFM1", "ALDH3A2", "ALG1", "ANKLE2", "APOO", "APOOL", "APP", "ARL15", "ARL6IP1", "ATAD3A", "ATAD3B", "ATAD5", "ATL2", "ATM", "ATP13A1", "ATP5B", "ATP5F1", "ATP5I", "ATP5L", "ATP6V0A1", "ATP6V0A2", "ATR", "AURKA", "B4GALT3", "BCAP31", "BCKDHB", "BCL2L13", "BRI3BP", "BSG", "C12orf73", "C19orf70", "C1QBP", "CALU", "CANX", "CCDC47", "CCDC58", "CDK5RAP3", "CERS1", "CERS2", "CETN2", "CHCHD3", "CISD1", "CLPTM1", "CLPTM1L", "CLPX", "CLUH", "COA3", "COMT", "COX15", "COX4I1", "COX6B1", "CPD", "CPOX", "CPT2", "CPVL", "CRTAP", "CTSA", "CUTA", "CXADR", "CYB5B", "CYB5D2", "CYB5R1", "CYC1", "CYP20A1", "CYP51A1", "DCTN4", "DCUN1D4", "DDRGK1", "DDX31", "DERL1", "DHCR7", "DHFR", "DHRS1", "DHRS7", "DHRS7B", "DHX36", "DIABLO", "DNAJB11", "DNAJC1", "DNAJC11", "DNAJC16", "DOLPP1", "EARS2", "EFCAB14", "EMD", "ENDOD1", "ERAP2", "ERLIN1", "FAM114A2", "FAM136A", "FAM162A", "FAM8A1", "FAR1", "FAR2", "FDFT1", "FGFR1OP", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "FLII", "FOXRED1", "GAA", "GADD45GIP1", "GALE", "GALNT4", "GDAP1", "GLB1", "GLDC", "GLG1", "GLUD1", "GM2A", "GOLGA5", "GOLIM4", "GPAA1", "GPD2", "GPR107", "GPR108", "GPR180", "GTPBP8", "GUSB", "HACD3", "HADH", "HAUS3", "HCCS", "HDGFL2", "HEXA", "HK2", "HLA-A", "HM13", "HMOX1", "HMOX2", "HS2ST1", "HSDL1", "HSP90B1", "IDH2", "IKBIP", "ILVBL", "IMMT", "INA", "ISOC1", "ITM2B", "KCTD12", "KDELR1", "KDELR3", "KIAA0319L", "KIF5B", "KLC4", "L2HGDH", "LAMP2", "LBR", "LETM1", "LMAN1", "LMF2", "LPCAT1", "MAN1A2", "MAN2A1", "MCL1", "METTL25", "MFN1", "MFSD10", "MFSD3", "MIA2", "MICU2", "MIEF1", "MIGA1", "MIPEP", "MMAB", "MPP2", "MRPL10", "MRPL20", "MRPL40", "MRPL46", "MRPL58", "MRPS25", "MRPS9", "MSMO1", "MTCH2", "MTDH", "MTFP1", "MTOR", "MTX1", "NAA40", "NAMPT", "NDC1", "NDUFA11", "NDUFA13", "NDUFA8", "NDUFAF4", "NDUFB1", "NDUFB4", "NDUFB9", "NDUFS2", "NEFM", "NEU1", "NLN", "NNT", "NPC1", "NRM", "NUCB1", "NUCB2", "OCIAD1", "OCLN", "OPA1", "OS9", "OSBP", "OSBPL9", "OXA1L", "OXSM", "P3H1", "P3H4", "P4HA1", "P4HA2", "PCM1", "PDHB", "PDK3", "PGRMC1", "PHB2", "PISD", "PITRM1", "PKP2", "PLA2G15", "PLD3", "PMPCA", "PNPLA8", "POLDIP2", "POLRMT", "POR", "PPT1", "PRCP", "PREB", "PRKAA2", "PSAP", "PTDSS1", "PTGES2", "QSOX2", "RAB11B", "RAB24", "RABL3", "RCN2", "RINT1", "RMDN1", "RMND1", "RPL10", "RPL27A", "RPL36", "RPN2", "RPS12", "RPS15", "RPS5", "RPS6", "RRP7A", "RTN3", "RTN4", "SAMM50", "SC5D", "SCAMP2", "SCARB1", "SCCPDH", "SCD", "SCPEP1", "SDCBP", "SDF4", "SDHB", "SEC11A", "SEC62", "SEC63", "SFXN2", "SFXN4", "SGPL1", "SLC16A1", "SLC25A10", "SLC25A13", "SLC25A17", "SLC25A20", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A5", "SLC25A6", "SLC35B2", "SLC39A14", "SLC4A7", "SLMAP", "SMIM12", "SMPD4", "SMYD4", "SNX27", "SOAT1", "SPNS1", "SPTLC1", "SQLE", "SSR1", "SSR4", "STARD3", "STT3B", "STX18", "STX3", "STX5", "SUN1", "SUN2", "SURF4", "SYNCRIP", "SYNJ2BP", "TAP1", "TAP2", "TDRKH", "TECR", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM9", "TIMMDC1", "TM7SF2", "TM9SF3", "TMCO1", "TMEM205", "TMEM209", "TMEM87A", "TMEM97", "TMLHE", "TMX4", "TOMM22", "TOMM5", "TRA2A", "TRABD", "TRMU", "TSPAN3", "TSPAN6", "TTC19", "TYSND1", "UQCRQ", "USP47", "UXT", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VMP1", "WDR48", "WLS", "YBX1", "ZADH2", "ZCCHC3", "ZNF326"]} \ No newline at end of file