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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Protein localization 0.5714587764986644 3.1351585822770223 0.0017176123313444 0.9115780243101622 1.0 77 P21796,A8MXV4,O75381,O43615,Q9Y512,Q13505,Q5JRX3,P46379,P51648,P08574,P05067,O75431,O43681,Q99595,Q9NR77,Q9Y5L4,Q15067,Q9NS69,O15254,P09601,O15228,Q10713,O60830,O43765,O14925,P12235,Q9Y5J9,Q9Y584,O75874,Q2T9J0,Q3ZCQ8,Q8N4H5,Q9Y5J7 33
Mitochondrial protein import 0.6600458826450163 3.094749492374001 0.0019697918877676 0.9380927109015248 1.0 36 P21796,Q9NS69,Q9Y584,Q9Y5J9,Q9Y5J7,Q3ZCQ8,O43615,P08574,O75431,Q10713,Q8N4H5,O60830,O14925,Q99595,Q9Y5L4,Q9Y512,Q13505,Q5JRX3 18
Sphingolipid de novo biosynthesis 0.8244233221640674 2.409115207564566 0.0159912491066434 0.999999999867708 1.0 10 P27544,O95470,Q06136,Q96G23 4
Biological oxidations 0.5181133934951134 2.3596190552841714 0.0182937098027231 0.9999999999951472 1.0 48 O15217,P07099,Q9NUJ1,Q8WUX2,O43169,P30837,Q8TB61 7
Heparan sulfate heparin hs gag metabolism 0.91946320637473 2.3221805179980484 0.0202232175547274 0.9999999999996976 1.0 5 Q96L58,P16278 2
Metabolism of porphyrins 0.7840464098361144 2.17755984557353 0.0294388217697287 1.0 1.0 9 P09601,P22830,P06132,P30519 4
Slc mediated transmembrane transport 0.6389175335458882 2.113193533624386 0.034584206543015 1.0 1.0 20 P12235,P53985,Q9UBX3,P11166,P30825,Q70HW3,Q8TB61,Q15043 8
Transport of inorganic cations anions and amino acids oligopeptides 0.7365933277009802 1.9592508306885517 0.0500834189322665 1.0 1.0 9 Q70HW3,P30825 2
Respiratory electron transport 0.4433732189068147 1.8987417745350963 0.0575984360928882 1.0 1.0 54 P21912,P51970,O14949,P00403,P03886,Q86Y39,P14854,O43676,Q9P0J0,P22695,Q16134 11
Heme biosynthesis 0.7374698682822161 1.850769689224881 0.0642026934318016 1.0 1.0 6 P22830,P06132 2
Heme degradation 0.9032652393002004 1.8458861913941975 0.0649087320751586 1.0 1.0 3 P30519 1
Phase i functionalization of compounds 0.6532518648441216 1.842494362488748 0.0654028703885141 1.0 1.0 15 P07099,O43169,P30837 3
Class i peroxisomal membrane protein import 0.7155896404580993 1.82198551892715 0.0684571829351345 1.0 1.0 8 Q8TB36,Q9NR77,P51648,O75381 4
Ras processing 0.7920005752233321 1.8093010274859664 0.0704042494653851 1.0 1.0 5 O60725 1
Metabolism of steroid hormones 0.7195526676545607 1.7708392359014165 0.0765874392632701 1.0 1.0 6 P30536,Q14849 2
Class a 1 rhodopsin like receptors 0.711008849979109 1.7651787175730105 0.0775337342625901 1.0 1.0 7 P07602,P42892 2
Peptide ligand binding receptors 0.711008849979109 1.7651787175730105 0.0775337342625901 1.0 1.0 7 P07602,P42892 2
Pre notch processing in golgi 0.805092392523367 1.7466063502721751 0.0807056449215681 1.0 1.0 4 Q9UBV2 1
Phase ii conjugation of compounds 0.4897641076273915 1.739501084048255 0.0819466617111059 1.0 1.0 31 O15217,Q9NUJ1,Q8TB61 3
Smac xiap regulated apoptotic response 0.8737247163165729 1.7313821127874478 0.0833836347662186 1.0 1.0 3 Q9NR28 1
Cdc6 association with the orc origin complex 0.8725880951060914 1.7269588896729455 0.0841750469145177 1.0 1.0 3 Q9Y619 1
Camk iv mediated phosphorylation of creb 0.8630020722150251 1.689606618852327 0.0911032388238943 1.0 1.0 3 Q13555 1
Transport of bile salts and organic acids metal ions and amine compounds 0.8590604026845666 1.6742237996025855 0.0940866237784785 1.0 1.0 3 Q15043,P53985 2
Biosynthesis of specialized proresolving mediators spms 0.8584906190160989 1.6719990362445936 0.0945245121170126 1.0 1.0 3 Q14914 1
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.4039806721834251 1.6586450593361457 0.0971873363419153 1.0 1.0 63 P21912,P51970,O14949,P00403,O75964,P03886,Q86Y39,P14854,O43676,Q9P0J0,P22695,Q16134 12
Fatty acid metabolism 0.402397437089498 1.6499698880236666 0.0989490950182734 1.0 1.0 58 A8MXV4,O43772,Q14914,Q9H7Z7,O15254,Q15165,Q53GQ0,P49748,P23786,P54646,Q16836,Q15067 12
Pink1 prkn mediated mitophagy 0.6771901087193454 1.6429310242871904 0.1003972051992492 1.0 1.0 8 Q9NS69,P21796 2
Metabolism of steroids 0.4311274556056462 1.639424434514508 0.1011248962772157 1.0 1.0 50 P38435,O95487,P30536,Q14849,Q9BWD1,P48449,O14975,Q16850,P04062,Q53GQ0,Q14739,P37268,Q15392,O76062,Q14534 15
Cholesterol biosynthesis 0.5813734528029607 1.623548176303327 0.1044722734840939 1.0 1.0 18 P48449,Q14739,Q15392,O76062,P37268 5
Complex i biogenesis 0.4750125665015133 1.6133003272445736 0.1066792754967915 1.0 1.0 30 P51970,P03886,Q86Y39,O43676,Q9P0J0 5
E2f enabled inhibition of pre replication complex formation 0.7718693590390531 1.611464641811613 0.1070784878374602 1.0 1.0 4 Q9Y619,Q9UBD5 2
Phase 0 rapid depolarisation 0.8404904061402622 1.6015792174791643 0.1092486895357449 1.0 1.0 3 Q13555 1
Endosomal vacuolar pathway 0.7688266199649365 1.5990258707375922 0.1098148543235564 1.0 1.0 4 P04439,P01889,Q9UIQ6 3
O linked glycosylation 0.7409833298594679 1.5968941357291948 0.1102893072187429 1.0 1.0 5 Q8N4A0,Q8NAT1,O43505 3
Mrna decay by 3 to 5 exoribonuclease 0.606744057987816 1.5901641751052535 0.1117978034187832 1.0 1.0 15 Q969T7 1
Sphingolipid metabolism 0.4763993871596508 1.5886232370387696 0.1121454788118565 1.0 1.0 26 P07602,Q06136,P16278,P27544,P51648,Q96G23,O95470,O43681 8
Carnitine metabolism 0.6730220070469806 1.5606772987688324 0.1185999101473456 1.0 1.0 6 P23786,O43772 2
Pregnenolone biosynthesis 0.7581017503357079 1.5551084188848636 0.1199202502371834 1.0 1.0 4 Q14849 1
Synthesis of pa 0.6165885102979988 1.4987054864029394 0.1339500527937145 1.0 1.0 12 Q8NAN2,O15228,Q9NPH0 3
The phototransduction cascade 0.6556790281061267 1.481512564944788 0.1384700391719386 1.0 1.0 6 P49356,P30419 2
Cytoprotection by hmox1 0.3906081086276221 1.4772044955185424 0.1396208291117759 1.0 1.0 66 P28074,P28070,P09601,P20618,P00403,P60900,P30519,P28072,P49721,P14854,P61289 11
O linked glycosylation of mucins 0.7327870601106354 1.451043467744206 0.1467677566962191 1.0 1.0 4 Q8N4A0,O43505 2
Apoptosis induced dna fragmentation 0.6202226312685362 1.4385994148723644 0.1502640522449918 1.0 1.0 10 P07305,P16403,P16402,P10412 4
Mitophagy 0.6040191155131117 1.4338018254577642 0.1516288239182239 1.0 1.0 12 Q9NS69,P21796 2
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.6097064732512746 1.4230848723279146 0.1547115531480982 1.0 1.0 11 P09601,P51648,P05067,O43681,P46379 5
Mastl facilitates mitotic progression 0.6399868499654581 1.4095683294195562 0.1586671840985303 1.0 1.0 6 P30153,P14635,O43768 3
Visual phototransduction 0.613343356143479 1.4044671286147774 0.1601797934830486 1.0 1.0 10 P49356,Q6NUM9,P30419 3
Egr2 and sox10 mediated initiation of schwann cell myelination 0.6302941646596475 1.391564446157337 0.1640543314804392 1.0 1.0 7 Q9NR77 1
Signaling by vegf 0.4439981602698418 1.3889300469023915 0.1648540226875887 1.0 1.0 32 Q9UQB8,Q8IZP0,P61586,Q7L576 4
Potential therapeutics for sars 0.4371179462636295 1.3820269573128292 0.1669634240890067 1.0 1.0 36 Q99720 1
Switching of origins to a post replicative state 0.3726010612283181 1.3742493852538458 0.1693642737956247 1.0 1.0 59 P28074,P28070,Q9UBD5,P20618,Q9Y619,Q13042,Q92530,P49736,P60900,Q99436,P28072,Q14566,P49721,P61289 14
Ire1alpha activates chaperones 0.4481629834922375 1.3730378696533132 0.1697405741770374 1.0 1.0 26 P43307,O43731,P49748 3
Synthesis of very long chain fatty acyl coas 0.6253332394750932 1.368319597695948 0.1712120590208861 1.0 1.0 7 Q53GQ0 1
Selective autophagy 0.4364976457800729 1.3632913224102132 0.1727907157618216 1.0 1.0 35 Q9NS69,P21796,P08670,Q13315,O95613,P54646 6
Regulation of mecp2 expression and activity 0.5681092837811151 1.3296281041691236 0.1836408336328716 1.0 1.0 14 Q14739,Q13555,Q9HCE1,P42858 4
Gpcr ligand binding 0.598285863612783 1.3295621827938229 0.1836625650666428 1.0 1.0 10 P07602,P42892 2
Orc1 removal from chromatin 0.3904476122116486 1.249326804876024 0.2115455677603244 1.0 1.0 50 P28074,P28070,Q9UBD5,P20618,Q9Y619,Q92530,P49736,P60900,Q99436,P28072,Q14566,P49721,P61289 13
G2 m dna replication checkpoint 0.6829398860434863 1.2450837854603676 0.2131009536603443 1.0 1.0 4 O95067,P14635 2
Signaling by notch 0.3651865155365686 1.2413876620859898 0.2144625747386312 1.0 1.0 63 Q96J02,P28074,P28070,P20618,P42224,Q99436,P60900,P67809,P28072,Q9HCE1,P49721,Q9UBV2,P61289 13
Acyl chain remodelling of pc 0.7443489514394854 1.2228990269303 0.2213678361481026 1.0 1.0 3 Q9NP80 1
Formation of senescence associated heterochromatin foci sahf 0.5817664727605502 1.2163691741913225 0.2238443211959642 1.0 1.0 9 P16403,P16402,P10412 3
Cdt1 association with the cdc6 orc origin complex 0.4098999480712482 1.2110521622488488 0.2258754138311109 1.0 1.0 40 P28070,P28074,Q9UBD5,P20618,Q9Y619,P60900,P28072,P49721,P61289 9
Apoptotic execution phase 0.4228745315983112 1.2092447668929258 0.2265688235957468 1.0 1.0 31 P07305,P08670,P42574,Q16625,P10412,P16403,P16402 7
Glycosaminoglycan metabolism 0.5379348499744805 1.2083621694388769 0.2269079846097661 1.0 1.0 15 P16278,O60512,Q7LGA3,Q96L58,Q8TB61 5
Cd28 co stimulation 0.5808772834880414 1.1842827650233352 0.2363011489559907 1.0 1.0 8 P42345 1
Phosphorylation of the apc c 0.55600523891341 1.184054940661873 0.236391315252092 1.0 1.0 12 P14635,Q13042,Q9UJX4,Q9H1A4,P30260,P06493,Q9UJX3 7
Energy dependent regulation of mtor by lkb1 ampk 0.5841400185695577 1.1746869163833484 0.2401199956905038 1.0 1.0 7 P54646 1
Transcriptional regulation by mecp2 0.4962146396970944 1.1688388883622556 0.2424685490413751 1.0 1.0 19 Q14739,Q13555,Q9HCE1,P42858 4
Apc c cdc20 mediated degradation of cyclin b 0.559408500956617 1.1669688323206646 0.2432229565354258 1.0 1.0 11 P14635,Q13042,Q9UJX4,Q9H1A4,P30260,P06493,Q9UJX3 7
Mtor signalling 0.5419638443115611 1.1470423475522382 0.2513641193539606 1.0 1.0 13 P06730,P42345,P54646 3
Abc family proteins mediated transport 0.3708741256220115 1.142212568183948 0.2533656730507236 1.0 1.0 53 P28070,P28074,P20618,P60900,P28072,Q9UBV2,P49721,P08183,P61289 9
Antigen processing cross presentation 0.3654853337421959 1.0877613352517 0.2767004826287105 1.0 1.0 53 P28074,P28070,Q03518,P20618,Q99436,P60900,P28072,P49721,Q9UIQ6,P61289 10
Nr1h2 and nr1h3 mediated signaling 0.5652700136066713 1.0859092637998418 0.277519137984664 1.0 1.0 7 Q8NB78 1
Metabolism of cofactors 0.5693938093513148 1.0840087568064558 0.2783609162318581 1.0 1.0 6 O75874 1
Degradation of beta catenin by the destruction complex 0.377928774395889 1.0781129743080475 0.2809833422715577 1.0 1.0 48 P28074,P28070,Q16537,P20618,P60900,P48729,P28072,P49721,P61289 9
Negative regulation of notch4 signaling 0.3926209098605248 1.060063162015957 0.2891158654086319 1.0 1.0 40 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Signaling by ctnnb1 phospho site mutants 0.5627941940715842 1.0535944811225637 0.2920686170026658 1.0 1.0 6 Q16537 1
Beta catenin phosphorylation cascade 0.5627941940715842 1.0535944811225637 0.2920686170026658 1.0 1.0 6 Q16537 1
Disassembly of the destruction complex and recruitment of axin to the membrane 0.5627941940715842 1.0535944811225637 0.2920686170026658 1.0 1.0 6 Q16537 1
Regulation of plk1 activity at g2 m transition 0.383585556006969 1.0467554276721127 0.2952123925085179 1.0 1.0 44 O94927,Q13561,P14635,P41208,O95067,O95684,O75935,O43805,O95613,Q9H6D7 10
Iron uptake and transport 0.4841369537552231 1.0400618752411086 0.2983111547205408 1.0 1.0 18 Q9Y487,P30519,Q93050 3
Phosphorylation of emi1 0.6949168914904116 1.0291355518338692 0.3034159820018201 1.0 1.0 3 P14635 1
Recruitment of mitotic centrosome proteins and complexes 0.3886305898503088 1.025136259120264 0.3052988989145184 1.0 1.0 40 O94927,Q96CW5,Q7Z4H7,Q13561,P41208,Q9Y5B8,O95684,O75935,P63167,Q15154,P30153,P06493,O43805,Q14204,O95613,P04350,Q9H6D7 17
Long term potentiation 0.5546289380156404 1.016021214955525 0.3096192841166767 1.0 1.0 6 Q14168,Q13555 2
Ras activation upon ca2 influx through nmda receptor 0.5546289380156404 1.016021214955525 0.3096192841166767 1.0 1.0 6 Q14168,Q13555 2
Unblocking of nmda receptors glutamate binding and activation 0.5546289380156404 1.016021214955525 0.3096192841166767 1.0 1.0 6 Q14168,Q13555 2
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.6036103141783191 1.0144734714936856 0.3103568816916788 1.0 1.0 5 Q8NB78 1
Signaling by erbb4 0.5451059704993891 1.0127967318913942 0.3111572620517226 1.0 1.0 8 Q96J02,P62993,Q15334 3
Scf skp2 mediated degradation of p27 p21 0.3841106022597208 1.00038507438919 0.317124190284993 1.0 1.0 41 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.6225638722889825 0.996223270181619 0.3191416753505853 1.0 1.0 4 P42224 1
Regulation of runx3 expression and activity 0.3894488114912226 0.9927540004088258 0.3208298518478063 1.0 1.0 37 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Negative regulation of nmda receptor mediated neuronal transmission 0.5408214885903382 0.9923245718471676 0.321039220572076 1.0 1.0 8 Q14168,Q13555 2
Cdc42 gtpase cycle 0.38931231786892 0.991592288530462 0.3213964525493877 1.0 1.0 37 Q9UQB8 1
Glycerophospholipid biosynthesis 0.39532524149505 0.98037902231871 0.3268990607917874 1.0 1.0 30 Q8NAN2,Q9NP80,O15228,Q8NCC3,Q9NPH0,Q9BZF1,Q96N66,P48651 8
Caspase mediated cleavage of cytoskeletal proteins 0.5427590696571166 0.9803231467791595 0.3269266325289477 1.0 1.0 7 P08670 1
Abacavir transport and metabolism 0.8885647607934545 0.9756515387128744 0.3292371750130405 1.0 1.0 2 P08183 1
Mitochondrial biogenesis 0.389855820446201 0.9747047856853378 0.3297067183909559 1.0 1.0 35 P48735,P54646,Q9Y512,Q13505,O75964 5
Interaction between l1 and ankyrins 0.6172686690189296 0.9745787461250568 0.3297692605697326 1.0 1.0 4 O15020,Q13813 2
Hedgehog ligand biogenesis 0.3790666907984561 0.9712607955210968 0.3314184262092268 1.0 1.0 42 P28074,P28070,P20618,P60900,P28072,P49721,Q9UBV2,P61289 8
Keratan sulfate biosynthesis 0.886814469078171 0.9694393709775492 0.332326016620017 1.0 1.0 2 O60512 1
Beta catenin independent wnt signaling 0.3386385519118312 0.9672222530697724 0.3334329400324414 1.0 1.0 58 P61586,P28074,P28070,P20618,P60900,P07737,P28072,Q9HCE1,P49721,P61289 10
Apoptotic cleavage of cell adhesion proteins 0.5348289953264815 0.9432856145056135 0.3455348319692692 1.0 1.0 7 Q16625 1
Signaling by pdgfr in disease 0.5347594521092812 0.942961296216703 0.3457007001079839 1.0 1.0 7 Q8TAF3,P42224 2
Synthesis of leukotrienes lt and eoxins ex 0.8786464410734994 0.9405428396820767 0.3469391861281004 1.0 1.0 2 Q14914 1
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.529805089206729 0.9398098450878598 0.347315107947391 1.0 1.0 8 Q9UQ84 1
Resolution of d loop structures 0.529805089206729 0.9398098450878598 0.347315107947391 1.0 1.0 8 Q9UQ84 1
Caspase activation via dependence receptors in the absence of ligand 0.8783547257876325 0.9395137721271586 0.3474670246562246 1.0 1.0 2 Q9Y5V3 1
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.5850317289613455 0.9361753793862008 0.349182897405994 1.0 1.0 5 P62993,O14654 2
Caspase activation via extrinsic apoptotic signalling pathway 0.584810711867067 0.9352474098362368 0.3496608108590744 1.0 1.0 5 Q9Y5V3,P42574 2
Signaling by notch4 0.3712110094532132 0.9339859649765864 0.3503111327907362 1.0 1.0 44 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Ngf stimulated transcription 0.6696819375547078 0.9315169882753696 0.3515862010700261 1.0 1.0 3 Q00535,P50570 2
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.5227192847184285 0.9279011466673072 0.3534588495660533 1.0 1.0 9 Q13042,Q9UJX4,Q9H1A4,P30260,Q9UJX3 5
Dna damage reversal 0.6055830507472065 0.9269911548504248 0.3539311267504446 1.0 1.0 4 Q9H1I8 1
Stabilization of p53 0.3768995308356643 0.9224708219142164 0.3562830431221557 1.0 1.0 40 P28074,P28070,P20618,Q13315,P60900,P28072,P49721,P61289 8
Antigen activates b cell receptor bcr leading to generation of second messengers 0.6672458909065406 0.9221631429725516 0.3564434849094544 1.0 1.0 3 P62993 1
Response of eif2ak4 gcn2 to amino acid deficiency 0.3496288364318894 0.9212603351158828 0.356914524489599 1.0 1.0 75 Q07020,P27635,P46778,P62917,P62424,Q02543,P83731,P47914,P46776,P42766,P62266,P25398,P15880,P62753,P50914,P39023,Q9Y3U8,P62910,P62841,P84098,P46782,P36578,P62847,P62750,P61313 25
The citric acid tca cycle and respiratory electron transport 0.3744448586812187 0.9161732392066588 0.3595760390147831 1.0 1.0 98 P21912,P21796,P53985,P48735,P51970,Q13423,O14949,Q15120,P00403,O75964,P03886,P14854,Q86Y39,O43676,Q9P0J0,P22695,Q16134 17
Regulation of hmox1 expression and activity 0.3624133723932199 0.909370454125428 0.3631546123193216 1.0 1.0 47 P28074,P28070,P09601,P20618,P60900,P28072,P49721,P61289 8
Arachidonic acid metabolism 0.5231215128066896 0.9080566201947144 0.3638483079522441 1.0 1.0 8 Q14914,Q15165 2
Hedgehog on state 0.3683300680172131 0.9077523067152614 0.3640091015822888 1.0 1.0 44 Q96J02,P28074,P28070,P20618,P48729,P60900,P28072,P49721,P61289 9
Signaling by kit in disease 0.5781208278659715 0.9072050229720108 0.3642983880039541 1.0 1.0 5 P42224 1
Parasite infection 0.3876926311742246 0.9036124407127109 0.366200942207036 1.0 1.0 26 Q9UQB8,Q7L576 2
Transport of vitamins nucleosides and related molecules 0.5262846223483194 0.9035108338959495 0.3662548409662807 1.0 1.0 7 P12235,P36404,Q8TB61 3
Mitochondrial calcium ion transport 0.4833025882745591 0.9028543016969658 0.366603226947872 1.0 1.0 15 P21796,P45880 2
Intra golgi traffic 0.4828206608044806 0.900173619986374 0.368027862477446 1.0 1.0 15 Q8TBA6,O00461,O60476 3
G1 s specific transcription 0.501427787881525 0.8998129064808058 0.3682198247276667 1.0 1.0 12 P00374,Q9Y619,P04818,P31350 4
Antigen processing ubiquitination proteasome degradation 0.3685071512277197 0.8987170268996528 0.3688034052773239 1.0 1.0 94 Q96J02,P28070,P28074,P20618,Q8IWV8,Q13042,P60900,P55786,P28072,O94874,P49721,Q96PU5,Q9UIQ6,P61289 14
Striated muscle contraction 0.5249904893673693 0.8975002634587397 0.3694520328871924 1.0 1.0 7 P08670,P09493 2
G1 s dna damage checkpoints 0.370201543470441 0.8921715374856638 0.372300995542328 1.0 1.0 42 P28074,P28070,P20618,Q13315,P60900,P28072,P49721,P61289 8
Interferon gamma signaling 0.4940128324768756 0.8916409649696925 0.3725854055559101 1.0 1.0 13 P01889,Q13555,P42224,Q13557 4
Auf1 hnrnp d0 binds and destabilizes mrna 0.369123209384972 0.8825615617252446 0.3774732043526179 1.0 1.0 42 P28074,P28070,P20618,Q14103,P60900,P28072,P49721,P61289 8
Eukaryotic translation elongation 0.3462444939724983 0.872561361695562 0.3829022085370352 1.0 1.0 76 Q07020,P27635,P46778,P62917,P62424,Q02543,P83731,P47914,P46776,P42766,P62266,P25398,P15880,P62753,P50914,P39023,Q9Y3U8,P62910,P62841,P84098,P46782,P36578,P62847,P62750,P61313 25
Vitamin d calciferol metabolism 0.654096424039319 0.8719282967660238 0.3832474955916698 1.0 1.0 3 P38435 1
Proton coupled monocarboxylate transport 0.8588098016335962 0.8710750992507945 0.3837131492379912 1.0 1.0 2 P53985 1
Mtorc1 mediated signalling 0.5062224723001814 0.8707262609512256 0.3839036360832928 1.0 1.0 10 P06730,P42345 2
Gamma carboxylation hypusine formation and arylsulfatase activation 0.5006112333523753 0.8678263755608533 0.3854893886793462 1.0 1.0 11 O60725,P38435,O43681 3
Dna damage telomere stress induced senescence 0.455259807332688 0.8658132890294277 0.3865925604147122 1.0 1.0 18 P16403,Q13315,P16402,P10412 4
Pcp ce pathway 0.3446671825934564 0.8512466499335192 0.3946323538378511 1.0 1.0 52 P61586,P28074,P28070,P20618,P60900,P07737,P28072,P49721,P61289 9
Regulation of runx2 expression and activity 0.3638918081030078 0.8511212843798487 0.3947019831390541 1.0 1.0 43 P28074,P28070,P20618,P42224,P60900,P28072,P49721,P61289 8
Mitotic g1 phase and g1 s transition 0.3423122292141113 0.8422818890997589 0.3996301860686753 1.0 1.0 75 P28074,P28070,Q9UBD5,Q07864,P14635,P20618,Q9Y619,Q92530,P49736,P60900,Q99436,P31350,P28072,Q14566,P00374,P49721,P61289 17
Autophagy 0.3410811121995406 0.8410398976812051 0.4003255834486914 1.0 1.0 53 Q9NS69,P21796,P08670,P42345,Q13315,Q8N4H5,O95613,P54646 8
Aurka activation by tpx2 0.3683114925687141 0.8350519351090485 0.403688467450523 1.0 1.0 39 O94927,Q7Z4H7,O14965,Q13561,P41208,P43034,O95684,O75935,P63167,Q68CZ6,Q15154,P30153,P06493,O43805,Q14204,O95613,P04350,Q9H6D7 18
Sulfur amino acid metabolism 0.4879149941671541 0.8301408366264506 0.406459160835884 1.0 1.0 12 Q13126,Q9UBX3 2
Transcriptional regulation by runx3 0.3631166896818829 0.8290962331338497 0.4070499550964639 1.0 1.0 42 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Metabolism of polyamines 0.3673604953858006 0.826841558719617 0.4083268712462671 1.0 1.0 39 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Asymmetric localization of pcp proteins 0.3682893802558211 0.8234530645118939 0.4102503974920939 1.0 1.0 38 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Signaling by wnt in cancer 0.5050495962637085 0.8227398176534548 0.4106559670319041 1.0 1.0 8 Q16537 1
Degradation of dvl 0.3681124814580531 0.8219407704234246 0.4111106074945461 1.0 1.0 38 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Degradation of axin 0.369295855436454 0.8215209452549865 0.4113495985682223 1.0 1.0 37 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Cross presentation of soluble exogenous antigens endosomes 0.369295855436454 0.8215209452549865 0.4113495985682223 1.0 1.0 37 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Regulation of ras by gaps 0.3632102458206777 0.802994924634725 0.4219776680890532 1.0 1.0 40 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Degradation of gli1 by the proteasome 0.3601494422144801 0.8027342142237867 0.422128372917105 1.0 1.0 42 Q96J02,P28074,P28070,P20618,P60900,P28072,P49721,P61289 8
Peroxisomal lipid metabolism 0.4698423374942154 0.7945880982030938 0.4268531438341651 1.0 1.0 14 A8MXV4,O14734,O15254,O43808,P51648,O14975,Q15067 7
Defective cftr causes cystic fibrosis 0.3556837927017292 0.7928752858552168 0.427850487638219 1.0 1.0 44 P28074,P28070,P20618,P60900,P28072,P49721,Q9UBV2,P61289 8
Antigen presentation folding assembly and peptide loading of class i mhc 0.4354128266568967 0.7917565448691455 0.4285026448045212 1.0 1.0 19 P01889,O95487,Q03518,Q9NZ08,Q6P179 5
Hedgehog off state 0.3335951093154463 0.7916736835856203 0.4285509708260222 1.0 1.0 54 Q96J02,P28074,P28070,P20618,P48729,P60900,P28072,P49721,P61289 9
Cellular response to chemical stress 0.3379597303176194 0.7833887441101213 0.4333988639361665 1.0 1.0 76 P28074,P28070,P09601,P20618,P00403,P60900,P30519,P28072,P49721,P14854,P61289 11
Cilium assembly 0.3297502530805101 0.7798087461397545 0.4355034575140495 1.0 1.0 69 O94927,Q96KP1,P41208,Q92973,A6NIH7,O75935,O95684,O43805,A0AVF1,O95613,Q9H6D7 11
Er quality control compartment erqc 0.5688946618507613 0.7797597363067765 0.4355323100493238 1.0 1.0 4 Q9UBV2 1
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.5467770702554529 0.7773157928682575 0.4369724797033332 1.0 1.0 5 P12235,P36404 2
Apoptosis 0.3525334428229966 0.7748327699797293 0.4384384826663519 1.0 1.0 90 P07305,P08670,P28070,P28074,P20618,Q99436,P60900,Q9Y5V3,Q16625,Q9NR28,P28072,P30419,P10412,P16403,P49721,P16402,P61289 17
Alpha oxidation of phytanate 0.564540540105011 0.7625698377184602 0.4457199784921637 1.0 1.0 4 P51648,O14975 2
Diseases of dna repair 0.4792218954774221 0.7607178013834142 0.4468256398709966 1.0 1.0 11 Q9UQ84 1
Signaling by hedgehog 0.3210052471714604 0.7592313437653417 0.447714179335668 1.0 1.0 63 Q96J02,P28074,P28070,P20618,P48729,P60900,P28072,P49721,Q9UBV2,P61289 10
Rac3 gtpase cycle 0.3604206444711811 0.7563218342695245 0.4494562602502285 1.0 1.0 38 Q9UQB8,Q8IZP0,Q14739,Q7L576 4
Costimulation by the cd28 family 0.4623961403978073 0.754727422231009 0.4504125492700188 1.0 1.0 14 P42345,Q16537 2
Acyl chain remodelling of ps 0.824095682613772 0.7524563680398517 0.4517766594146704 1.0 1.0 2 Q9BZF1 1
Acyl chain remodelling of pe 0.8240956826137716 0.7524563680398514 0.4517766594146706 1.0 1.0 2 Q9NP80 1
Abc transporter disorders 0.3493874865113333 0.7518313949530259 0.4521524593890418 1.0 1.0 45 P28074,P28070,P20618,Q92530,Q99436,P60900,P28072,O14678,P49721,Q9UBV2,P61289 11
Hdr through homologous recombination hrr 0.3672375489870694 0.7467272894779453 0.4552281935243449 1.0 1.0 27 Q07864,Q13535,Q13315,Q9UQ84,Q92547 5
Disinhibition of snare formation 0.617157864021019 0.733706728913544 0.4631274965698129 1.0 1.0 3 P05771,P17252 2
Interleukin 4 and interleukin 13 signaling 0.4635662584944918 0.7319325045022952 0.464209765466065 1.0 1.0 13 P08670,P09601,P42224 3
Peroxisomal protein import 0.383397697976066 0.7244829706352708 0.4687692782352346 1.0 1.0 24 A8MXV4,O75381,Q2T9J0,O75874,O15254,O15228,O14975,Q15067 8
Cellular response to hypoxia 0.3537304226403651 0.7207310898508624 0.4710749801853793 1.0 1.0 40 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
G alpha i signalling events 0.3639889923038882 0.7201214017860038 0.4714502514397094 1.0 1.0 26 P07602,Q13555,Q13557,Q00535,P05067 5
Cyclin a b1 b2 associated events during g2 m transition 0.4653443986123398 0.715150808926028 0.4745158611581055 1.0 1.0 12 Q9Y570,O95067 2
Phospholipid metabolism 0.337127511009099 0.7102223712247278 0.4775662500958142 1.0 1.0 49 Q8NAN2,Q9NP80,O15228,Q9Y217,Q9NPH0,Q10713,Q8NCC3,Q8TBX8,Q9BZF1,Q96N66,P48651 11
Regulation of cholesterol biosynthesis by srebp srebf 0.3623274643538478 0.7086813750374439 0.4785222253033747 1.0 1.0 27 O76062,P48449,P37268 3
Cd28 dependent vav1 pathway 0.5292631543982509 0.7061737744038109 0.4800800773866935 1.0 1.0 5 P62993,Q13177 2
Cyclin a cdk2 associated events at s phase entry 0.346020731362864 0.7056256753858441 0.4804209529148635 1.0 1.0 44 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Recruitment of numa to mitotic centrosomes 0.3473862113502265 0.7033724422651692 0.4818236757165581 1.0 1.0 43 O94927,Q96CW5,Q7Z4H7,Q13561,P41208,Q9Y5B8,O95684,O75935,P63167,Q15154,P30153,P06493,O43805,Q14204,O95613,P04350,Q9H6D7 17
Degradation of cysteine and homocysteine 0.4829996162125013 0.692686964597213 0.4885060213377339 1.0 1.0 6 Q9UBX3 1
Small interfering rna sirna biogenesis 0.5454979567816891 0.6883043204674493 0.4912611615561302 1.0 1.0 4 O75569 1
Uch proteinases 0.3365728402314842 0.6857259062959193 0.4928859671366026 1.0 1.0 48 P28074,P28070,P20618,P60900,Q9Y4E8,P28072,Q8NB78,P49721,P61289 9
Irs mediated signalling 0.5445592320882395 0.684685709600808 0.4935422685978583 1.0 1.0 4 P62993 1
Activation of gene expression by srebf srebp 0.4177005860009611 0.6837195468677612 0.4941522779504472 1.0 1.0 19 O76062,P48449,P37268 3
Metabolism of folate and pterines 0.4749720847263926 0.6832909496728332 0.4944230118639012 1.0 1.0 8 P00374,Q9H2D1,P34896,P34897 4
Collagen biosynthesis and modifying enzymes 0.4622793014011453 0.6772006550630594 0.4982786521968179 1.0 1.0 11 O75718,Q32P28 2
Negative regulators of ddx58 ifih1 signaling 0.5218113043161645 0.6763061352426372 0.4988462982684403 1.0 1.0 5 Q96J02,Q7Z434 2
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3283061958725586 0.6668182639447977 0.5048882250920816 1.0 1.0 51 P28074,P28070,P20618,Q13042,P60900,P28072,P49721,P61289 8
Srp dependent cotranslational protein targeting to membrane 0.3420650488092731 0.6641972825755825 0.5065640524792459 1.0 1.0 90 Q07020,P27635,P46778,P62917,Q02543,P62424,Q15629,P51571,P83731,P47914,P46776,P42766,P67812,P62266,P25398,P15880,P62753,P50914,P39023,P62910,P62841,Q9Y3U8,P84098,P62847,P46782,P43307,P36578,P62750,P61313 29
Tnfr2 non canonical nf kb pathway 0.3423167515916862 0.6583656069748801 0.5103032298935064 1.0 1.0 43 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Dna replication pre initiation 0.3112999183948307 0.6542962353343847 0.5129209708487386 1.0 1.0 63 P28074,P28070,Q9UBD5,Q07864,P20618,Q9Y619,Q92530,P49736,P60900,Q99436,P28072,Q14566,P49721,P61289 14
Runx1 regulates transcription of genes involved in differentiation of hscs 0.3417286414238545 0.6531593770913536 0.5136535360902783 1.0 1.0 43 Q96J02,P28074,P28070,P20618,P60900,P28072,P49721,P61289 8
Anchoring of the basal body to the plasma membrane 0.346680116980224 0.6495299636646757 0.5159958854751263 1.0 1.0 39 O94927,Q13561,P41208,O95684,O75935,O43805,O95613,Q9H6D7 8
Regulation of pten stability and activity 0.3394124036961087 0.6463680252358415 0.5180410428088553 1.0 1.0 44 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Interferon alpha beta signaling 0.4595235084223072 0.6444486761549253 0.5192845287725136 1.0 1.0 10 P01889,P42224,Q9Y3Z3,P04439,P10321 5
Beta oxidation of pristanoyl coa 0.5111282607886597 0.6339726694119455 0.5260986585936407 1.0 1.0 5 O15254 1
Rho gtpases activate wasps and waves 0.4094332650165902 0.6339054951479862 0.5261424991557591 1.0 1.0 19 Q9UQB8,Q7L576 2
Pyruvate metabolism and citric acid tca cycle 0.3464163950656075 0.6292390048440469 0.5291925967757956 1.0 1.0 37 P21796,P53985,P48735,Q13423,Q15120 5
Apc c mediated degradation of cell cycle proteins 0.3071913900512499 0.629076674212462 0.5292988605080535 1.0 1.0 58 P28074,P28070,P20618,Q13042,P60900,P28072,P49721,P61289 8
Cristae formation 0.4082871666962428 0.6270372766333873 0.5306348005830945 1.0 1.0 19 Q9Y512,Q13505,O75964 3
Hsf1 dependent transactivation 0.4211090422058928 0.6259912871606759 0.5313206561949286 1.0 1.0 17 P42345,Q13555,Q13557 3
Mapk6 mapk4 signaling 0.3239405164506 0.6245326661045901 0.5322778243722748 1.0 1.0 51 P28074,P28070,P20618,P60900,P28072,Q9HCE1,P49721,P61289 8
Ovarian tumor domain proteases 0.4575225218046831 0.6185430181337122 0.5362174501019554 1.0 1.0 9 Q7Z434,Q13546,P61586 3
Rac2 gtpase cycle 0.3417808773381804 0.6179711236928699 0.5365943735708032 1.0 1.0 40 Q8IZP0,Q86XL3,Q7L576,Q14739,Q9Y512,Q13505 6
Collagen formation 0.4360564849566964 0.615943666011756 0.5379317007265452 1.0 1.0 14 O75718,Q32P28 2
The role of gtse1 in g2 m progression after g2 checkpoint 0.3224572669540618 0.6102172563169419 0.5417179001400465 1.0 1.0 51 P28070,P28074,O95067,P14635,P20618,Q92530,Q99436,P60900,P28072,P49721,P61289 11
Hdr through single strand annealing ssa 0.4120062968469012 0.6098721552177357 0.5419464990054257 1.0 1.0 18 Q13315,Q92547,Q9UQ84,Q13535 4
Urea cycle 0.7791715285880796 0.6063325880990088 0.5442939228910504 1.0 1.0 2 Q9Y619 1
Intrinsic pathway of fibrin clot formation 0.7785880980163171 0.6045016559319815 0.5455101686057127 1.0 1.0 2 P42785 1
Formation of fibrin clot clotting cascade 0.7785880980163171 0.6045016559319815 0.5455101686057127 1.0 1.0 2 P42785 1
Regulation of tp53 expression and degradation 0.4500091667323698 0.5997201811120332 0.5486927362288521 1.0 1.0 10 Q13315 1
Regulation of tp53 activity 0.3165962371852271 0.5962397482713129 0.5510150754660579 1.0 1.0 53 P40937,Q13535,P42345,Q13315,Q9UQ84,Q92547,Q92804,P54646 8
Synaptic adhesion like molecules 0.501020650284299 0.5945070527274453 0.5521730265510727 1.0 1.0 5 O95197,Q15334 2
Polo like kinase mediated events 0.4549421631965117 0.5929960836994804 0.5531837731946019 1.0 1.0 8 Q5TKA1,O95067,P14635 3
Inactivation of cdc42 and rac1 0.5770417556668971 0.5903641029911555 0.5549465714725605 1.0 1.0 3 O94813 1
Signaling by retinoic acid 0.4392711441674543 0.5855565996955114 0.5581735208116907 1.0 1.0 12 Q15120 1
Homologous dna pairing and strand exchange 0.401055015526977 0.5839332006849896 0.5592652549469261 1.0 1.0 19 Q13315,Q92547,Q9UQ84,Q13535 4
Regulation of tp53 activity through phosphorylation 0.3396195308192402 0.5658277467972713 0.5715108824634576 1.0 1.0 36 P40937,Q13535,Q13315,Q9UQ84,Q92547,P54646 6
Dectin 1 mediated noncanonical nf kb signaling 0.3312478517962368 0.5610105428923651 0.5747903500171443 1.0 1.0 43 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Signaling by notch3 0.4500873903129513 0.5605607598243167 0.5750970082145135 1.0 1.0 7 P67809 1
Downstream signaling events of b cell receptor bcr 0.3276008623298952 0.5550226118064372 0.5788791941666314 1.0 1.0 45 P28074,P28070,P20618,Q04864,P60900,P28072,P49721,P61289 8
Activation of atr in response to replication stress 0.374721431646329 0.5522392393982728 0.5807844534604611 1.0 1.0 22 P40937,Q9UBD5,Q13535,Q9Y619,Q14566 5
Ptk6 regulates proteins involved in rna processing 0.7605017502917062 0.5487229080321666 0.5831956227268029 1.0 1.0 2 Q07666 1
Assembly and cell surface presentation of nmda receptors 0.4304382097971638 0.5427279151620055 0.5873171511974642 1.0 1.0 12 Q14168,Q13555,Q13557 3
Downregulation of erbb4 signaling 0.7578763127187758 0.5407911728459587 0.5886515277464301 1.0 1.0 2 Q96J02 1
G2 m checkpoints 0.3310516187652229 0.5381655128153368 0.5904627869703045 1.0 1.0 91 P40937,P28074,P14635,Q13535,P49736,P49721,Q9Y619,P60900,O96028,P28070,Q9UBD5,O95067,P20618,Q13315,Q92530,Q9UQ84,Q99436,Q92547,P28072,Q14566,P61289 21
The nlrp3 inflammasome 0.4801721064261686 0.5152063938132377 0.6064088015703029 1.0 1.0 5 P09601 1
Inflammasomes 0.4801721064261686 0.5152063938132377 0.6064088015703029 1.0 1.0 5 P09601 1
Purinergic signaling in leishmaniasis infection 0.4801721064261686 0.5152063938132377 0.6064088015703029 1.0 1.0 5 P09601 1
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.4283079834539508 0.5150818216441743 0.606495844996009 1.0 1.0 11 Q13042,Q9UJX4,Q9H1A4,P30260,Q9UJX3 5
Apc cdc20 mediated degradation of nek2a 0.4283079834539508 0.5150818216441743 0.606495844996009 1.0 1.0 11 Q13042,Q9UJX4,Q9H1A4,P30260,Q9UJX3 5
Prevention of phagosomal lysosomal fusion 0.5526699737379724 0.5080062584682039 0.6114489541730608 1.0 1.0 3 O14964,Q9H267 2
Release of apoptotic factors from the mitochondria 0.7462077012835349 0.5060803400807005 0.6128002513693827 1.0 1.0 2 Q9NR28 1
Dopamine neurotransmitter release cycle 0.7459159859976721 0.5052242226299986 0.6134013590486362 1.0 1.0 2 O14936 1
Interleukin 1 signaling 0.3143214259319233 0.4960775391408979 0.6198397054444311 1.0 1.0 49 P28070,P28074,P20618,P05067,P60900,P28072,P49721,P61289 8
Eukaryotic translation initiation 0.3362944199200906 0.4951136026943496 0.6205199323987332 1.0 1.0 100 Q9Y262,Q07020,O00303,P20042,P27635,P46778,P62917,Q02543,P62424,P83731,P47914,P46776,P42766,P06730,Q9UI10,P62266,P18077,P25398,P15880,P63173,Q14152,P62753,P60866,P50914,P39023,O60841,P26373,P11940,O15372,P55010,P62910,P62841,Q02878,Q9Y3U8,P18621,P84098,P60228,P62847,P46782,P36578,P49770,P23588,P62750,P61313 44
Met activates ras signaling 0.4933135220005358 0.4950149805023005 0.6205895460459219 1.0 1.0 4 P62993 1
Activation of the pre replicative complex 0.3794352683243827 0.4943810430567995 0.6210370994442398 1.0 1.0 20 Q07864,Q9Y619,Q9UBD5,Q14566 4
Signaling by the b cell receptor bcr 0.3149619118519973 0.4856965199108076 0.6271823514280781 1.0 1.0 48 P28074,P28070,P20618,Q04864,P60900,P28072,P49721,P61289 8
Regulation of mrna stability by proteins that bind au rich elements 0.2972957872091089 0.481602468648169 0.6300883721743613 1.0 1.0 65 P28074,P28070,P20618,Q14103,Q92973,P60900,P28072,P49721,P61289 9
Transcriptional regulation by runx2 0.3003772233082631 0.4810615105601474 0.6304727823700602 1.0 1.0 55 P28074,P28070,P20618,P42224,P60900,P28072,P49721,P61289 8
Ub specific processing proteases 0.3118862459619781 0.4731538152683643 0.6361034450866931 1.0 1.0 79 P21796,P28070,P28074,P20618,Q96K76,P45880,Q99436,P60900,Q9Y4E8,Q9UPU5,P28072,Q8TAF3,P49721,P61289 14
Disorders of transmembrane transporters 0.3057018168538074 0.4655357393163601 0.6415478493470519 1.0 1.0 74 P28074,O00231,O75832,P49721,O14678,P49720,P11166,P60900,Q9BW27,Q8N1F7,P28070,P53985,Q9UBV2,Q13438,Q8NFH4,Q9BTX1,P35613,P20618,Q92530,Q99436,P28072,Q92621,P61289 23
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.4284974294990559 0.4634963136503025 0.6430086565679938 1.0 1.0 6 P04439,P01889,P10321 3
Glutathione conjugation 0.3965001739248481 0.4620537481332866 0.6440427771145687 1.0 1.0 16 O15217 1
Dap12 interactions 0.4224679625574674 0.4454229472460108 0.6560141319948607 1.0 1.0 7 P62993,P01889 2
Interleukin 1 family signaling 0.302409399727146 0.4383416413386012 0.6611386441223017 1.0 1.0 52 P28070,P28074,P20618,P05067,P60900,P28072,P49721,P61289 8
Insulin receptor recycling 0.4139151735433805 0.4366343960103656 0.6623765136985416 1.0 1.0 10 Q9Y487 1
Wax and plasmalogen biosynthesis 0.4570916718139309 0.431381049142253 0.6661913270346371 1.0 1.0 5 O15228 1
Ros and rns production in phagocytes 0.4149539385881988 0.4305515272867495 0.6667944928303151 1.0 1.0 9 Q9Y487 1
Tcf dependent signaling in response to wnt 0.2906130416469749 0.4237291146055186 0.6717633795243423 1.0 1.0 64 P28074,P28070,Q16537,P20618,P60900,P48729,P28072,P49721,P61289 9
Rac1 gtpase cycle 0.3027412561884768 0.4232574563432396 0.6721074305790085 1.0 1.0 51 Q9UQB8,Q14739,Q7L576 3
Pyruvate metabolism 0.3787395602154851 0.4225083187449163 0.6726540300665123 1.0 1.0 18 P21796,Q15120 2
Signaling by csf3 g csf 0.4175730670633846 0.4205982295995718 0.6740484867354801 1.0 1.0 6 P62993,P42224 2
Acyl chain remodeling of cl 0.5236946280271443 0.4160649080318696 0.677362507547095 1.0 1.0 3 Q6UWP7 1
Regulation of pten localization 0.7109101516919503 0.4069941190779217 0.6840123075186064 1.0 1.0 2 P46934 1
Programmed cell death 0.3251020442094664 0.3926482465981129 0.6945792999651812 1.0 1.0 99 P07305,P08670,P28070,P28074,P20618,Q99436,P60900,Q9Y5V3,Q9NR28,P28072,P30419,P10412,P16403,P49721,P16402,P61289 16
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.4627077734616104 0.3913600495636524 0.6955311179601995 1.0 1.0 4 O14975 1
Cargo concentration in the er 0.3834473404352407 0.3739641899995183 0.7084309585976332 1.0 1.0 15 Q96PC5,O95487,O75396,Q15436,Q9Y6B6,P49257,P49755 7
Raf activation 0.3905410381173761 0.3726889555942347 0.7093799573766768 1.0 1.0 13 Q13555,Q16537 2
E2f mediated regulation of dna replication 0.3957902959158579 0.3598575536095289 0.7189536607272162 1.0 1.0 10 Q9Y619,Q9UBD5 2
Transferrin endocytosis and recycling 0.3927726587085924 0.3569607471607919 0.7211211916339006 1.0 1.0 11 Q9Y487 1
Organelle biogenesis and maintenance 0.3265459553410298 0.3561623394831185 0.7217189938149833 1.0 1.0 104 O94927,P48735,Q96KP1,Q9Y512,P41208,A6NIH7,O95684,O75935,O75431,Q92973,Q10713,O43805,A0AVF1,O95613,P54646,Q13505,O75964,Q9H6D7 18
Abc transporters in lipid homeostasis 0.6893232205367588 0.3513157668681632 0.7253514676377495 1.0 1.0 2 P40855 1
Fcgamma receptor fcgr dependent phagocytosis 0.3123992405445487 0.3496772709642828 0.7265809132346956 1.0 1.0 36 Q9UQB8,Q7L576 2
Arms mediated activation 0.5010213014298368 0.349509739129996 0.7267066605206141 1.0 1.0 3 Q9ULH0,P46108 2
Activation of bad and translocation to mitochondria 0.3976044405492187 0.3485385999773864 0.7274357302979666 1.0 1.0 7 Q04917,P62258,Q9Y3B8,P31946,P63104,P61981 6
Intraflagellar transport 0.3844921128136811 0.3454686273090276 0.7297420918722912 1.0 1.0 13 A0AVF1 1
Leishmania infection 0.304673620665442 0.3448874311606439 0.7301790000283006 1.0 1.0 44 Q9UQB8,Q8IZP0,P09601,Q7L576 4
Deadenylation dependent mrna decay 0.3068653729145389 0.3443311509957446 0.7305972598888362 1.0 1.0 42 Q969T7 1
Fanconi anemia pathway 0.3917295459462889 0.343233091778322 0.7314231114771852 1.0 1.0 10 O15360,Q13535 2
Maturation of sars cov 2 nucleoprotein 0.4273910546883474 0.3311412111915574 0.7405378239360538 1.0 1.0 5 P48729 1
Neddylation 0.2988580077373184 0.3303699063300395 0.7411204774601488 1.0 1.0 80 P28070,P28074,P20618,P61962,O94888,P28072,Q92564,P49721,P61289 9
Nonsense mediated decay nmd 0.3072034695946636 0.3289186131269054 0.7422172051549696 1.0 1.0 88 Q07020,P27635,P46778,Q02543,P62917,P62424,Q9HAU5,P83731,P47914,P46776,P42766,P62266,P25398,P15880,P62753,P50914,P39023,P11940,Q9Y5S9,Q9Y3U8,P62910,P62841,P84098,P62847,P46782,P36578,P62750,P61313 28
Sensory perception 0.3109859184442977 0.3249462869960014 0.7452217241801327 1.0 1.0 29 P49354,O14936,P49356,P30419,Q6NUM9 5
Unwinding of dna 0.3871830641419861 0.3248932960425352 0.7452618308808869 1.0 1.0 10 Q14691,Q14566,Q9BRT9,P49736 4
Ion homeostasis 0.3824951993531051 0.3242246864741848 0.7457679335976262 1.0 1.0 12 P16615,Q13555 2
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.4870148818208488 0.3110845327635962 0.7557363592636686 1.0 1.0 3 P18887,P49916 2
Fceri mediated nf kb activation 0.2980192759667406 0.2997843408586305 0.7643416604799307 1.0 1.0 45 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Regulation of lipid metabolism by pparalpha 0.3209885861536692 0.2984432393644076 0.7653648915499027 1.0 1.0 24 P23786,P37268 2
Interconversion of nucleotide di and triphosphates 0.3549147471515151 0.2971446360641409 0.7663560878029867 1.0 1.0 18 P32321,P31350,P17812,Q9H773 4
Signaling by ntrk2 trkb 0.415273802434199 0.2931552053091572 0.7694035215954342 1.0 1.0 5 Q00535 1
Pre notch processing in the endoplasmic reticulum 0.6642357059509965 0.2918765925903298 0.7703809810040094 1.0 1.0 2 Q9H488 1
Receptor mediated mitophagy 0.4281961471103388 0.2861883969905698 0.7747338301220321 1.0 1.0 4 P68400,P67870,Q96HS1 3
Synthesis of pc 0.4281961471103387 0.2861883969905695 0.7747338301220323 1.0 1.0 4 Q8NF37,P68400,P67870 3
Cytosolic iron sulfur cluster assembly 0.380157538988339 0.284448273026978 0.7760668695370891 1.0 1.0 6 P28340,Q9Y5Y2,P18074 3
Cardiac conduction 0.3664834322292609 0.2796575531537595 0.7797402470094905 1.0 1.0 14 P16615,Q13555 2
Association of tric cct with target proteins during biosynthesis 0.3455806265583319 0.2735359665588623 0.7844412487960484 1.0 1.0 19 O95302,P61962,P04062 3
Synthesis of pips at the golgi membrane 0.375850179575519 0.2703923828210674 0.7868583995612659 1.0 1.0 7 Q99570,Q10713,Q9BTU6,Q01968 4
Tp53 regulates metabolic genes 0.3021275051892217 0.2689935817081404 0.7879346217561614 1.0 1.0 35 P42345,P14854,P00403,P54646 4
Hdms demethylate histones 0.3739731958710872 0.2686101772235513 0.7882296797551946 1.0 1.0 9 Q8IUF8,Q8NB78 2
Selenoamino acid metabolism 0.2997783545217443 0.2668063174603965 0.7896182898993938 1.0 1.0 87 Q07020,P27635,P62917,P46778,Q02543,P62424,P83731,P47914,P46776,P42766,P62266,P25398,P15880,P62753,P50914,P39023,Q9Y3U8,P62910,P62841,P84098,P62847,P46782,P36578,P62750,P61313 25
Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.373597653382283 0.2627029243513304 0.792779562629919 1.0 1.0 7 O95864,Q15067 2
Regulation of tp53 activity through methylation 0.3990362445779513 0.2452518640882549 0.8062614205683813 1.0 1.0 5 Q13315 1
Unfolded protein response upr 0.2944030727267683 0.2450092867892386 0.8064492406635275 1.0 1.0 42 P43307,O43731,P49748 3
Synthesis of dna 0.2930182195137068 0.2423918069745062 0.8084765822117415 1.0 1.0 83 P40937,P28074,P49736,O00231,O75832,P49721,P25786,P49720,Q9Y619,Q9UJX4,P60900,Q14691,P28070,Q9UBD5,Q9BRT9,Q13042,P28340,P35251,Q07864,P20618,Q92530,Q99436,P28072,Q14566,P61289 25
Regulation of localization of foxo transcription factors 0.3973722627737263 0.2405481866432726 0.8099053120779307 1.0 1.0 5 P31946,P61981,Q9Y3B8,P63104 4
Nef and signal transduction 0.6394399066511128 0.2391438363364514 0.8109940512415188 1.0 1.0 2 Q13177 1
Muscle contraction 0.2981051963100638 0.2345665921506006 0.8145451417364558 1.0 1.0 30 P16615,P08670,Q13555,P09493,P67936 5
Clec7a dectin 1 signaling 0.2828342579071922 0.2303152615517009 0.8178468023520908 1.0 1.0 50 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Class i mhc mediated antigen processing presentation 0.3291179821331243 0.2277332508911805 0.8198536210891607 1.0 1.0 120 Q96J02,P28070,P28074,Q03518,P20618,Q8IWV8,Q13042,Q9NZ08,Q99436,P60900,P55786,P28072,O94874,P49721,Q96PU5,Q9UIQ6,P61289 17
Condensation of prometaphase chromosomes 0.3591415097165106 0.2232167381202418 0.8233668254321824 1.0 1.0 11 P67870,O95067,P14635,P06493,Q9NTJ3 5
Citric acid cycle tca cycle 0.3343913953092807 0.2171902241057155 0.8280601028934353 1.0 1.0 19 Q13423,P48735 2
Basigin interactions 0.3594181524083094 0.2161911850182368 0.8288387244191511 1.0 1.0 7 P53985 1
Tcr signaling 0.277800060534964 0.2145291967801383 0.8301344011764302 1.0 1.0 52 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Activation of nima kinases nek9 nek6 nek7 0.3875680369723733 0.2136458109474173 0.8308232721232991 1.0 1.0 5 O95067 1
Sars cov infections 0.2650336510577555 0.2123220500264757 0.8318557941388909 1.0 1.0 60 Q99720 1
Translation of replicase and assembly of the replication transcription complex 0.4457007165738509 0.2112477038751588 0.8326939882489282 1.0 1.0 3 Q14457 1
Ubiquinol biosynthesis 0.6231038506417639 0.2078442351871098 0.8353505920570219 1.0 1.0 2 Q5T2R2 1
Glyoxylate metabolism and glycine degradation 0.3471848899435917 0.1989950716553425 0.8422665997503913 1.0 1.0 14 Q9NR77 1
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.6102683780630179 0.1852210886695879 0.8530556289032685 1.0 1.0 2 O00767 1
Gene silencing by rna 0.2837027793995669 0.1769549136272998 0.8595438043204204 1.0 1.0 44 Q9Y2W6,Q8N1F7,Q9BTX1,O75569,O15397,Q9BW27,Q9HAV4,Q92621,P84243,P30876,Q9UPY3 11
Wnt mediated activation of dvl 0.4280711992996954 0.1753040287855855 0.860840746279087 1.0 1.0 3 P68400,P67870 2
Interleukin 2 family signaling 0.3718285070521977 0.1734758002322974 0.8622774481015636 1.0 1.0 5 P42224 1
Post chaperonin tubulin folding pathway 0.3429229904377127 0.1639259784034345 0.8697894159222226 1.0 1.0 10 P36404,Q99426,P04350,Q15813 4
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.3408425980105299 0.1620571120160597 0.871260879329687 1.0 1.0 12 P14635,Q04917,O96017,P62258,Q9Y3B8,P63104,P31946,O14757,P06493,P27348,P61981 11
Tysnd1 cleaves peroxisomal proteins 0.3382517127349996 0.1569348184140217 0.8752962187142137 1.0 1.0 6 Q15067 1
Cell surface interactions at the vascular wall 0.3301674416246321 0.1508166319287057 0.8801203659568533 1.0 1.0 16 P53985,P35613,Q92896 3
Copi dependent golgi to er retrograde traffic 0.2700647665673653 0.1487795761737488 0.881727567107305 1.0 1.0 52 P24390,O15260,O43731,Q9Y3B3 4
Signaling by braf and raf1 fusions 0.283001796817405 0.1432376679851902 0.886102481778535 1.0 1.0 26 P51114,Q9NRY5,Q13555,Q13557 4
Repression of wnt target genes 0.4096877735629023 0.1422834244644535 0.8868561386788751 1.0 1.0 3 Q13547,P56545 2
Cellular response to starvation 0.2863853495858441 0.1415400585213412 0.8874433164366236 1.0 1.0 87 Q07020,P42345,P27635,P62917,P46778,Q02543,P62424,P83731,P47914,P46776,P42766,P62266,P25398,P15880,P62753,P50914,P39023,Q9Y3U8,P62910,P62841,P84098,P62847,P46782,P36578,P62750,P61313 26
Synthesis of pips at the late endosome membrane 0.4085205719288126 0.1403418737041288 0.8883898812536017 1.0 1.0 3 O00443,Q99570 2
Beta oxidation of very long chain fatty acids 0.3309247551252054 0.1378355442742063 0.8903703921907957 1.0 1.0 6 Q15067,O14734 2
Constitutive signaling by aberrant pi3k in cancer 0.3318726263511486 0.1359938917954624 0.8918261097451079 1.0 1.0 7 P84095,O00459,O43815,P63000,P62993,Q06124 6
Synthesis of ketone bodies 0.3642464757777919 0.1331036529868075 0.8941114061896982 1.0 1.0 4 P35610 1
Traf6 mediated irf7 activation 0.3622300058377179 0.1292693016153648 0.8971445613537148 1.0 1.0 4 Q7Z434,Q92793,Q14258 3
Synthesis of pips at the early endosome membrane 0.3512408759124123 0.1268503467295648 0.8990588466313107 1.0 1.0 5 Q9BTU6,Q13614,O00443,Q99570 4
Mitotic g2 g2 m phases 0.3021705637720378 0.1268090308947352 0.8990915478255628 1.0 1.0 104 P28070,P28074,Q9Y570,O95067,P41208,P20618,Q99436,O95684,O75935,P60900,P28072,O43805,O95613,P49721,Q9H6D7,P61289 16
Initiation of nuclear envelope ne reformation 0.314448153528688 0.1240807955389309 0.9012513035815166 1.0 1.0 19 Q86XL3,Q14739,O95067,P14635 4
Synthesis of bile acids and bile salts 0.3283063850230044 0.122999254248562 0.9021076885066376 1.0 1.0 8 O14975,O14734 2
Bile acid and bile salt metabolism 0.3283063850230044 0.122999254248562 0.9021076885066376 1.0 1.0 8 O14975,O14734 2
Pten regulation 0.2646066094272705 0.1171897054243023 0.906709724588814 1.0 1.0 69 P28074,P28070,P42345,P20618,P60900,P28072,Q9HCE1,P49721,P61289 9
Fc epsilon receptor fceri signaling 0.2612567569353283 0.1163366251350615 0.9073857600066012 1.0 1.0 55 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Nuclear signaling by erbb4 0.3540572095738536 0.114375367184203 0.9089402399766964 1.0 1.0 4 P61201,P16949,O75376 3
Inactivation of csf3 g csf signaling 0.3535660402855362 0.113513338635996 0.909623588729098 1.0 1.0 4 P42224 1
Processing of dna double strand break ends 0.2786293887516965 0.1053560712097548 0.9160932721005086 1.0 1.0 32 Q13535,Q13315,Q9UQ84,Q92547,O96028 5
Reduction of cytosolic ca levels 0.3483781670593537 0.1046370700247687 0.916663798528194 1.0 1.0 4 P16615 1
Platelet calcium homeostasis 0.3483781670593537 0.1046370700247687 0.916663798528194 1.0 1.0 4 P16615 1
C type lectin receptors clrs 0.2580344392372017 0.1039619566755278 0.917199539099908 1.0 1.0 56 P28074,P28070,P20618,P60900,P28072,P49721,P61289 7
Regulation of expression of slits and robos 0.3167196097988332 0.0982781570909549 0.9217114223215828 1.0 1.0 122 P28074,Q07020,P27635,P46778,Q02543,P62917,P62424,Q9HAU5,P83731,P49721,P47914,P46776,P42766,P49720,P60900,P62266,P25398,P15880,P62753,P28070,P50914,P39023,P11940,Q9Y5S9,P62910,P62841,Q9Y3U8,P84098,P62847,P46782,P36578,P20618,Q92530,Q99436,P28072,P62750,P61313,P61289 38
Acetylcholine regulates insulin secretion 0.5329638273045663 0.0853718947570628 0.9319657363056192 1.0 1.0 2 P17252 1
Translocation of slc2a4 glut4 to the plasma membrane 0.2749473342419675 0.084648017991827 0.9325412231931804 1.0 1.0 37 Q9UIQ6 1
Signaling by insulin receptor 0.312297232165056 0.0826387262777357 0.934138807455722 1.0 1.0 16 Q9Y487 1
Smooth muscle contraction 0.3161256602535522 0.0824275609358001 0.9343067201593842 1.0 1.0 12 P09493 1
Caspase activation via death receptors in the presence of ligand 0.3621243069740397 0.0778614141259601 0.937938293259012 1.0 1.0 3 P49327,Q13546 2
Regulation by c flip 0.3621243069740397 0.0778614141259601 0.937938293259012 1.0 1.0 3 P49327,Q13546 2
Postmitotic nuclear pore complex npc reformation 0.2983949947001896 0.0698115131935389 0.9443436833343152 1.0 1.0 20 Q8N1F7,Q9BTX1,Q92973,Q9BW27,Q92621 5
Slc transporter disorders 0.2720788982631609 0.0697555611687354 0.9443882180227016 1.0 1.0 29 Q8N1F7,P53985,Q9BTX1,P35613,P11166,Q9BW27,Q92621 7
Synthesis of ip2 ip and ins in the cytosol 0.3510358914502571 0.0669743834743622 0.9466020964257024 1.0 1.0 3 Q9NPH2,Q01968 2
Dscam interactions 0.5093348891481966 0.0663951087833555 0.9470632642376402 1.0 1.0 2 P63000 1
Downregulation of erbb2 signaling 0.2987733644859855 0.0663240677409366 0.9471198221223552 1.0 1.0 6 Q93034,Q16543,P07900,P40818,Q9UNE7 5
Mapk family signaling cascades 0.2888866408272798 0.0639614569615103 0.949000916825092 1.0 1.0 98 P28074,P62993,P49721,O60725,P49354,Q13555,P49720,P60900,Q99956,P28070,Q16537,Q13557,Q9HCE1,P20618,Q92530,Q99436,Q14168,P49356,P28072,P61289 20
Sensory processing of sound by outer hair cells of the cochlea 0.3091334894613579 0.063495306539401 0.9493720965434158 1.0 1.0 14 Q00013,O00159,P35579,P15311,Q9Y2J2,O14936,Q14651,Q13813,P26038,Q12965,P35241,Q6IBS0,Q01082 13
Free fatty acids regulate insulin secretion 0.5035005834305901 0.0624318184362622 0.950218956925894 1.0 1.0 2 O60488 1
Signaling by wnt 0.2834622869855941 0.0612894311123469 0.9511287077298918 1.0 1.0 93 P61586,P28070,P28074,Q16537,P20618,Q5T9L3,P60900,P48729,P07737,P28072,Q9HCE1,P49721,P61289 13
Cellular response to heat stress 0.2514986226925401 0.0587940247187854 0.9531161678130816 1.0 1.0 63 Q9BTX1,Q13555,Q13535,P42345,Q13315,Q9UL15 6
Josephin domain dubs 0.3376130726583159 0.055690072729378 0.955588708044737 1.0 1.0 3 P54725,P55072 2
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.3018067408633914 0.0490619610329471 0.9608699175789932 1.0 1.0 10 Q99873,P14635,Q07812,Q9Y3B8,P06493 5
Chaperone mediated autophagy 0.2979177644736464 0.0451708243881943 0.9639711492698012 1.0 1.0 9 P08670 1
Transcriptional regulation by e2f6 0.3016574532189987 0.0450382689901415 0.9640768056458712 1.0 1.0 11 Q15022,P31350,Q9UBK9,Q9H9B1 4
Apoptotic cleavage of cellular proteins 0.2915966195008246 0.0417598419744366 0.9666901485300228 1.0 1.0 20 P08670,P42574,Q16625 3
Ptk6 regulates cell cycle 0.462660443407237 0.0415847538151508 0.9668297274213024 1.0 1.0 2 P11802 1
Mapk3 erk1 activation 0.2997664915353244 0.0411734704179952 0.967157603271924 1.0 1.0 4 Q06124,P06493,Q02750 3
P75ntr negatively regulates cell cycle via sc1 0.4393232205367725 0.034154869152547 0.972753654723684 1.0 1.0 2 Q13547 1
Coenzyme a biosynthesis 0.4247374562427096 0.0307784505598145 0.975446226239006 1.0 1.0 2 Q9NVE7 1
Fceri mediated ca 2 mobilization 0.2861622500025457 0.0293296119246617 0.9766017101558 1.0 1.0 4 P62993 1
Transcriptional regulation by ventx 0.2969209544631312 0.0283390981838733 0.9773916972707308 1.0 1.0 15 Q13042,Q9UJX4,Q9H1A4,P30260,Q9UJX3,Q9HCE1,Q9H9B1 7
Regulation of foxo transcriptional activity by acetylation 0.3868144690781762 0.0253344850569517 0.9797881676543448 1.0 1.0 2 Q96EB6 1
Activation of kainate receptors upon glutamate binding 0.2734169827837834 0.0249474876011509 0.9800968493779516 1.0 1.0 3 Q15334,P63218 2
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.2927210054574535 0.0240608447820409 0.980804075610764 1.0 1.0 11 Q13042,Q9UJX4,Q9H1A4,P30260,Q9UJX3 5
Defective ripk1 mediated regulated necrosis 0.3620186697782922 0.0235516553076928 0.9812102349173112 1.0 1.0 2 Q13546 1
Notch2 activation and transmission of signal to the nucleus 0.3538506417736373 0.0231644561427062 0.9815190908838702 1.0 1.0 2 Q04721 1
Signaling by notch2 0.3538506417736373 0.0231644561427062 0.9815190908838702 1.0 1.0 2 Q04721 1
Notch hlh transcription pathway 0.2784107508033837 0.0230706683456689 0.9815939027258842 1.0 1.0 7 Q04721,Q13547,Q92769,O75376,Q9UBN7,Q92793 6
Extracellular matrix organization 0.2643985556108514 0.0189232129748467 0.9849023615791266 1.0 1.0 33 P42574,P35613,Q32P28,O14936,P05067,O75718,O60568,P13674 8
Apoptotic factor mediated response 0.2786361317043846 0.0154202791455845 0.987696884931121 1.0 1.0 8 Q07021,P42574,Q9NR28 3
Notch1 intracellular domain regulates transcription 0.2784921098772699 0.0151838430815175 0.987885511530776 1.0 1.0 8 Q13547,Q92769,O75376,Q9UBN7,P63208,Q13616,Q92793 7
Pyroptosis 0.2735767885386306 0.0131602920458309 0.9894999092527208 1.0 1.0 5 P42574 1
Cobalamin cbl vitamin b12 transport and metabolism 0.2709489051094944 0.0109192961132754 0.9912878353434508 1.0 1.0 5 Q9Y4U1,Q99707,Q96EY8,O14678 4
Defects in cobalamin b12 metabolism 0.2709489051094944 0.0109192961132754 0.9912878353434508 1.0 1.0 5 Q9Y4U1,Q99707,Q96EY8,O14678 4
G alpha z signalling events 0.2738164815897203 0.0077394533841547 0.9938248712832728 1.0 1.0 8 P04899,P63096,P63218,P08754,P05771,P17252,Q05655 7