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  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/consensus.joblib +3 -0
  4. interpro_active_site/df_merge.tsv +1 -0
  5. interpro_active_site/metrics.json +7 -0
  6. interpro_active_site/paths.json +1 -0
  7. interpro_active_site/result.tsv +4 -0
  8. interpro_active_site/selections.json +1 -0
  9. interpro_binding_site/advanced/idx2term.json +1 -0
  10. interpro_binding_site/basic/idx2term.json +1 -0
  11. interpro_binding_site/consensus.joblib +3 -0
  12. interpro_binding_site/df_merge.tsv +1 -0
  13. interpro_binding_site/metrics.json +7 -0
  14. interpro_binding_site/paths.json +1 -0
  15. interpro_binding_site/result.tsv +6 -0
  16. interpro_binding_site/selections.json +1 -0
  17. interpro_conserved_site/advanced/idx2term.json +1 -0
  18. interpro_conserved_site/advanced/plot_0.png +3 -0
  19. interpro_conserved_site/basic/idx2term.json +1 -0
  20. interpro_conserved_site/basic/plot_0.png +3 -0
  21. interpro_conserved_site/consensus.joblib +3 -0
  22. interpro_conserved_site/df_merge.tsv +3 -0
  23. interpro_conserved_site/metrics.json +7 -0
  24. interpro_conserved_site/paths.json +1 -0
  25. interpro_conserved_site/result.tsv +30 -0
  26. interpro_conserved_site/selections.json +1 -0
  27. interpro_domain/advanced/idx2term.json +1 -0
  28. interpro_domain/advanced/plot_0.png +3 -0
  29. interpro_domain/basic/idx2term.json +1 -0
  30. interpro_domain/basic/plot_0.png +3 -0
  31. interpro_domain/basic/plot_1.png +3 -0
  32. interpro_domain/basic/plot_2.png +3 -0
  33. interpro_domain/basic/plot_3.png +3 -0
  34. interpro_domain/basic/plot_4.png +3 -0
  35. interpro_domain/basic/plot_5.png +3 -0
  36. interpro_domain/basic/plot_6.png +3 -0
  37. interpro_domain/consensus.joblib +3 -0
  38. interpro_domain/df_merge.tsv +3 -0
  39. interpro_domain/metrics.json +7 -0
  40. interpro_domain/paths.json +1 -0
  41. interpro_domain/result.tsv +223 -0
  42. interpro_domain/selections.json +0 -0
  43. interpro_family/advanced/idx2term.json +1 -0
  44. interpro_family/advanced/plot_0.png +3 -0
  45. interpro_family/basic/idx2term.json +1 -0
  46. interpro_family/basic/plot_0.png +3 -0
  47. interpro_family/consensus.joblib +3 -0
  48. interpro_family/df_merge.tsv +5 -0
  49. interpro_family/metrics.json +7 -0
  50. interpro_family/paths.json +1 -0
interpro_active_site/advanced/idx2term.json ADDED
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+ {}
interpro_active_site/basic/idx2term.json ADDED
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+ {}
interpro_active_site/consensus.joblib ADDED
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+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:4dbfa694c1539f5bca10ca6b3f7fd808f26a8aa909d6dc216dcb5f0943651e80
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+ size 81046
interpro_active_site/df_merge.tsv ADDED
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+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3367,
4
+ "annotations_size": 55,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.963636363636364
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+ }
interpro_active_site/paths.json ADDED
@@ -0,0 +1 @@
 
 
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+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C009/C009_val_log2fc"}
interpro_active_site/result.tsv ADDED
@@ -0,0 +1,4 @@
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Serine carboxypeptidase, serine active site [IPR018202] 0.9270267059802074 1.899970077632607 0.0574370465046611 0.9613570615315836 0.1824352789042546 3 Q9HB40 1
3
+ Histidine acid phosphatase active site [IPR033379] 0.7916281366831787 1.3907569564963538 0.1642991396385227 0.9999483825304494 0.4107478490963068 3 Q9NPH0 1
4
+ Cysteine peptidase, cysteine active site [IPR000169] 0.4647953585053244 0.3132673885459714 0.7540775242377409 1.0 0.8824311453845904 4 P53634 1
interpro_active_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADSS", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "BUB1", "CAMK1", "CAMK2D", "CAMK2G", "CAMKK2", "CAPN1", "CAPN2", "CASP2", "CASP3", "CDK1", "CDK11B", "CDK12", "CDK2", "CDK4", "CDK6", "CDK7", "CDK9", "CHEK1", "CHEK2", "CHUK", "CIT", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "FASN", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSK3A", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "IRAK1", "LDHA", "LDHB", "LONP1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP3K4", "MAP3K6", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MKNK1", "MTMR1", "MTMR2", "MTMR6", "NEK9", "NME1", "NME2", "NME3", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PPIP5K2", "PREP", "PRKAA1", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "STK38", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TRIO", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "WNK1"], "leading_proteins": ["ACP6", "CTSC", "SCPEP1"]}
interpro_binding_site/advanced/idx2term.json ADDED
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interpro_binding_site/basic/idx2term.json ADDED
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interpro_binding_site/consensus.joblib ADDED
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+ size 76558
interpro_binding_site/df_merge.tsv ADDED
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1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_binding_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3367,
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+ "annotations_size": 33,
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+ "title": "Average number of proteins per term",
6
+ "value": 4.848484848484849
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+ }
interpro_binding_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C009/C009_val_log2fc"}
interpro_binding_site/result.tsv ADDED
@@ -0,0 +1,6 @@
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ EF-Hand 1, calcium-binding site [IPR018247] 0.4126611024752674 1.0061409186985686 0.3143477876417733 0.9999960967344832 0.5800951008815716 35 P80303,Q9Y680,Q02818 3
3
+ Peptidase M16, zinc-binding site [IPR001431] 0.5847709696609261 0.8664482998074589 0.3862443665738526 0.9999998991092814 0.5800951008815716 5 O75439,Q10713,P14735,O43847 4
4
+ Beta tubulin, autoregulation binding site [IPR013838] 0.3903763496647924 0.3306227640781026 0.7409294491187797 1.0 0.8150223940306577 7 P04350,P07437 2
5
+ 2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016] 0.4625445897740661 0.2652822442525383 0.7907920416822707 1.0 0.8418108830811268 3 P11182,P36957 2
6
+ Aconitase family, 4Fe-4S cluster binding site [IPR018136] 0.3922734026745932 0.0531990774086965 0.9575732906974056 1.0 0.9655463738771544 2 P21399 1
interpro_binding_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Aryldialkylphosphatase, zinc-binding site [IPR017947]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "ARG2", "AURKA", "AURKB", "BPNT1", "BUB1", "CALU", "CAMK1", "CAMK2D", "CAMK2G", "CAMKK2", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK12", "CDK2", "CDK4", "CDK6", "CDK7", "CDK9", "CHEK1", "CHUK", "CIT", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "DST", "EHD4", "EIF2AK2", "EPS15", "EPS15L1", "FKBP10", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQGAP1", "IQGAP2", "IQGAP3", "IRAK1", "LETM1", "MACF1", "MAP2K1", "MAP2K2", "MAP2K3", "MAP2K4", "MAP3K4", "MAP3K6", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MKNK1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO5A", "MYO9B", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKCD", "PRKCSH", "PSAT1", "PTER", "RAB18", "RCN1", "RCN2", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK38", "STK4", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "USP32", "VRK1"], "leading_proteins": ["ACO1", "DBT", "DLST", "FKBP7", "IDE", "NRDC", "NUCB1", "NUCB2", "PMPCA", "PMPCB", "TUBB", "TUBB4A"]}
interpro_conserved_site/advanced/idx2term.json ADDED
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+ {"0": "Syntaxin/epimorphin, conserved site [IPR006012]"}
interpro_conserved_site/advanced/plot_0.png ADDED

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interpro_conserved_site/basic/idx2term.json ADDED
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interpro_conserved_site/basic/plot_0.png ADDED

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interpro_conserved_site/consensus.joblib ADDED
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interpro_conserved_site/df_merge.tsv ADDED
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1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Proteasome beta-type subunit, conserved site [IPR016050] 3 8 2.170742983788602 0.0299506060315755 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 0.0009934566258862 0.0001014210629885 6.494328716879693e-05 5.5966724052351854e-05
3
+ Syntaxin/epimorphin, conserved site [IPR006012] 5 6 2.044770150109241 0.0408775239149676 2.592233009708738 5.847087378640777 0.9961908981999794 0.2839139128702306 1.4759357288864456 1.4239341993278547 1.138258151200134 0.2914162845337057 1.0 1.0 1.0 0.0388074443523606 0.0028246814840344
interpro_conserved_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
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+ {
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+ "type_of_task": "ranksum",
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+ "signature_size": 3367,
4
+ "annotations_size": 287,
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+ "title": "Average number of proteins per term",
6
+ "value": 2.7421602787456445
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+ }
interpro_conserved_site/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C009/C009_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
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1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.8239431878705331 2.170742983788602 0.0299506060315755 0.9998378807554664 0.1534968559118245 8 P28074,P49721,P28072 3
3
+ Syntaxin/epimorphin, conserved site [IPR006012] 0.8378458792026084 2.044770150109241 0.0408775239149676 0.9999937214750758 0.1892233768321891 6 Q86Y82,O15400,Q12846,Q9P2W9,Q13190 5
4
+ Haem oxygenase conserved site [IPR018207] 0.9821693907875186 1.7679202362849018 0.0770742392422993 0.9999999998993389 0.2697598373480478 2 P30519 1
5
+ Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.868311533888225 1.680980824274459 0.0927666392755768 0.9999999999992666 0.3025457440010289 3 P55899,P01889 2
6
+ Sterol reductase, conserved site [IPR018083] 0.9554234769687964 1.663293854677338 0.096253628243264 0.9999999999997572 0.3065023757584007 2 Q9UBM7 1
7
+ Ubiquitin specific protease, conserved site [IPR018200] 0.5824316685667746 1.5737192141418488 0.1155523777609635 0.9999999999999996 0.3444225554780737 15 Q9UPU5,Q70CQ2,Q96K76,O94966 4
8
+ Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.7177275431291088 1.3918829492075877 0.1639578459283492 1.0 0.3962609429861317 5 Q96Q15,P78527,P42345,P42356 4
9
+ Tetraspanin, conserved site [IPR018503] 0.8537890044576527 1.2641676918744107 0.206169844375406 1.0 0.4516850788987904 2 O43657 1
10
+ Thioredoxin, conserved site [IPR017937] 0.5644026767540631 1.1887906019001049 0.2345220771831799 1.0 0.4807702582255189 10 O43396,Q9H1E5,P07237 3
11
+ Ribosomal protein L30, conserved site [IPR018038] 0.817830609212482 1.1240446261317358 0.2609940946729288 1.0 0.5138038086957019 2 Q6DKI1 1
12
+ Ribosomal protein L3, conserved site [IPR019926] 0.7934621099554242 1.0301048383616915 0.302960794220886 1.0 0.557370179111502 2 P09001 1
13
+ Chromo domain, conserved site [IPR023779] 0.5696814282762861 0.9520780491573124 0.3410574005191034 1.0 0.6058295218822095 6 Q14781 1
14
+ GHMP kinase, ATP-binding, conserved site [IPR006203] 0.7625557206537898 0.9127798796287792 0.3613583223886074 1.0 0.6300274151564562 2 Q03426 1
15
+ DNA mismatch repair, conserved site [IPR014762] 0.6568690006180578 0.8823484200937021 0.3775884196031973 1.0 0.6300274151564562 3 P54278 1
16
+ Ribosomal protein L24e, conserved site [IPR023442] 0.7533432392273409 0.8783153220566142 0.379772623073404 1.0 0.6300274151564562 2 P83731 1
17
+ Clathrin adaptor complex, small chain [IPR000804] 0.5988123141011653 0.7411590125693636 0.4585970319981274 1.0 0.6810978675010326 4 P53680 1
18
+ Fork head domain conserved site 2 [IPR030456] 0.7150074294205062 0.7381987531306733 0.4603936804710813 1.0 0.6810978675010326 2 P85037 1
19
+ Fork head domain conserved site1 [IPR018122] 0.7150074294205062 0.7381987531306733 0.4603936804710813 1.0 0.6810978675010326 2 P85037 1
20
+ Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770] 0.623774145616643 0.4374587152318777 0.6617787104773796 1.0 0.815152317197459 2 O60573 1
21
+ 3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180] 0.61069836552749 0.3996513546418383 0.6894133260307362 1.0 0.8399131084858728 2 Q16836 1
22
+ Cyclic nucleotide-binding, conserved site [IPR018488] 0.5863298662704322 0.3336944503716921 0.7386101377460557 1.0 0.8787055863516107 2 P10644 1
23
+ Tubulin, conserved site [IPR017975] 0.3903763496647924 0.3306227640781026 0.7409294491187797 1.0 0.8787055863516107 7 P04350,P07437 2
24
+ Heat shock protein 70, conserved site [IPR018181] 0.3653185708675777 0.3173218427492338 0.7509994050312272 1.0 0.8864694839845033 10 P48723 1
25
+ ABC transporter-like, conserved site [IPR017871] 0.3675905453520224 0.2589324030579824 0.7956873965144684 1.0 0.9208156564502116 7 Q9NRK6 1
26
+ Ribosomal protein L24/L26, conserved site [IPR005825] 0.4820208023774163 0.1288807056180055 0.8974520440150093 1.0 0.9625908071160192 2 P61254 1
27
+ Heat shock protein Hsp90, conserved site [IPR019805] 0.3804994054696665 0.1132684510062468 0.9098177286903352 1.0 0.967102548644912 3 P14625,P08238 2
28
+ Ubiquitin conserved site [IPR019954] 0.4502228826151579 0.0926621623217572 0.9261719577266554 1.0 0.9736679555587916 2 P46379 1
29
+ Kinesin motor domain, conserved site [IPR019821] 0.2631297070790375 0.0636304132145029 0.9492645145613952 1.0 0.9799960995651812 14 Q2M1P5 1
30
+ GTP1/OBG, conserved site [IPR006074] 0.388112927191681 0.0514369841744974 0.9589773146561968 1.0 0.9864748720656936 2 P55039 1
interpro_conserved_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AF4 interaction motif [IPR043639]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Carbonic anhydrase, alpha-class, conserved site [IPR018338]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Deoxyribonuclease, TatD-related, conserved site [IPR018228]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FHF complex subunit HOOK interacting protein, KELAA motif [IPR045668]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Helix-turn-helix motif [IPR000047]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0012, conserved site [IPR001110]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFF4", "AFG3L2", "AHCY", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "APEX1", "APP", "ARIH2", "ARSA", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BARD1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BUD31", "CA8", "CAD", "CALR", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX2", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDKAL1", "CDX2", "CECR2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CPOX", "CRELD2", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX33", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DIS3L2", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB4", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPY30", "DRG1", "DRG2", "DSG2", "DST", "DTL", "DTYMK", "DUS2", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECT2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FAM160B2", "FARP1", "FBL", "FCGRT", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GFM2", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GMPR2", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPSM1", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXA10", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPA1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "IVD", "KDM2A", "KDM5A", "KDM5C", "KDSR", "KIF11", "KIF1A", "KIF1B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MKRN2", "MLH1", "MOCS1", "MPI", "MPP1", "MPP6", "MPST", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "MVK", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFM", "NES", "NIT1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP2", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PEX1", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHGDH", "PHIP", "PI4KA", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PMS2", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAD18", "RAE1", "RANBP2", "RARS", "RARS2", "RBFA", "RCL1", "RDH13", "RDX", "RELA", "RIDA", "RIOK2", "RNF114", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SH3RF1", "SHPRH", "SLC1A5", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STMN1", "STOM", "STRN", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE2", "TATDN1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM25", "TRIM28", "TRIM33", "TRIM4", "TRIM71", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB3", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP32", "USP34", "USP47", "USP48", "USP5", "USP7", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB10", "AP2S1", "BAG6", "CBX2", "DHCR7", "DRG2", "EIF4E2", "FCGRT", "FOXK1", "HADH", "HLA-B", "HMOX2", "HSP90AB1", "HSP90B1", "HSPA13", "KIF7", "MRPL3", "MTOR", "MVK", "P4HB", "PI4KA", "PMS2", "PRKAR1A", "PRKDC", "PSMB2", "PSMB5", "PSMB6", "RPL24", "RPL26", "RPL7L1", "SMG1", "STX12", "STX18", "STX4", "STX5", "STX7", "TMX4", "TSPAN6", "TUBB", "TUBB4A", "TXNL1", "USP19", "USP24", "USP34", "USP47"]}
interpro_domain/advanced/idx2term.json ADDED
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+ {"0": "Target SNARE coiled-coil homology domain [IPR000727]"}
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+ {"0": "Target SNARE coiled-coil homology domain [IPR000727]", "1": "LIS1 homology motif [IPR006594]", "2": "K Homology domain [IPR004087]", "3": "Pleckstrin homology domain [IPR001849]", "4": "Histidine kinase/HSP90-like ATPase [IPR003594]", "5": "SWAP/Surp [IPR000061]", "6": "K Homology domain, type 1 [IPR004088]"}
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+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:04bc4fdf6beab103c7546f62237e075f30b779dc369865ecb78ab5b7ed5c32ce
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+ size 390327
interpro_domain/df_merge.tsv ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Linker histone H1/H5, domain H15 [IPR005818] 3 7 2.261092464540327 0.02375353191184 4.621359223300971 6.101941747572815 -1.4616951902178734 0.1781780847215095 1.4983259581225516 0.4870120076915772 1.3151991134793464 0.2676299008151665 1.0 0.0470522829573702 0.0930016660897952 6.494328716879693e-05 0.0009328306623149
3
+ Target SNARE coiled-coil homology domain [IPR000727] 6 7 2.1663867321202708 0.0302816469740418 3.5024271844660193 8.266990291262136 0.5942034778060385 0.4012381903331891 1.9023475359698396 2.183694577914796 1.0582363712887182 0.3038263160802639 1.0 1.0 1.0 0.002932051876052 0.0010532104032369
interpro_domain/metrics.json ADDED
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1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3367,
4
+ "annotations_size": 2785,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.2244165170556554
7
+ }
interpro_domain/paths.json ADDED
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+ {"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C009/C009_val_log2fc"}
interpro_domain/result.tsv ADDED
@@ -0,0 +1,223 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Linker histone H1/H5, domain H15 [IPR005818] 0.8619926662555559 2.261092464540327 0.02375353191184 1.0 0.1207182233110849 7 P16402,P16403,P10412 3
3
+ Target SNARE coiled-coil homology domain [IPR000727] 0.8380952380952389 2.1663867321202708 0.0302816469740418 1.0 0.1362429512483145 7 Q86Y82,O15400,Q9UNK0,O95721,Q12846,Q13190 6
4
+ ERAP1-like C-terminal domain [IPR024571] 0.9527348394768118 1.994678475796944 0.046077958409302 1.0 0.1748325806129513 3 Q9UIQ6,Q9NZ08 2
5
+ Oxoglutarate/iron-dependent dioxygenase [IPR005123] 0.7860033549286565 1.9562884741780255 0.0504311811716795 1.0 0.1843186870907185 7 Q32P28 1
6
+ Prolyl 4-hydroxylase, alpha subunit [IPR006620] 0.7860033549286565 1.9562884741780255 0.0504311811716795 1.0 0.1843186870907185 7 Q32P28 1
7
+ Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.8556499769917811 1.9292564339151337 0.0536990353290165 1.0 0.1888280472112513 5 Q9UIQ6,Q9NZ08 2
8
+ Aminopeptidase N-like , N-terminal domain [IPR045357] 0.8556499769917811 1.9292564339151337 0.0536990353290165 1.0 0.1888280472112513 5 Q9UIQ6,Q9NZ08 2
9
+ Syntaxin, N-terminal domain [IPR006011] 0.914684898929844 1.8542357351897525 0.0637054416768361 1.0 0.2094813187488935 3 Q86Y82,Q12846 2
10
+ EXPERA domain [IPR033118] 0.9783060921248145 1.752834325701413 0.0796304492584161 1.0 0.2400116895938191 2 Q5BJF2 1
11
+ Phospholipase D/Transphosphatidylase [IPR001736] 0.9702823179791976 1.721471523589816 0.0851652952309414 1.0 0.2517891159428576 2 Q8IV08 1
12
+ Domain of unknown function DUF3517 [IPR021905] 0.8769029588478432 1.7132355971322155 0.0866692052420281 1.0 0.2549602134870709 3 Q9UPU5 1
13
+ MHC class I-like antigen recognition-like [IPR011161] 0.8545005173068798 1.7002768012572478 0.089078871960206 1.0 0.2573705621051046 4 P55899,P01889 2
14
+ Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862] 0.8500867079744704 1.6837896390777014 0.0922223302701183 1.0 0.2613840399238715 4 Q32P28 1
15
+ FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179] 0.6668978853463166 1.661326670537091 0.0966478563354067 1.0 0.268359202287246 10 Q96AY3,Q5T1M5,Q9Y680,Q14318 4
16
+ Drought induced 19 protein type, zinc-binding domain [IPR008598] 0.8589255564619249 1.6456698107241277 0.0998317577047203 1.0 0.2741927467531026 3 Q9Y508 1
17
+ CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.8561236623067752 1.6351146699946428 0.1020250114280538 1.0 0.277063718297883 3 Q96F07,Q7L576 2
18
+ TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8472073202516333 1.6014846254000583 0.1092696226044325 1.0 0.2864677699344775 3 Q96G23 1
19
+ MHC class I, alpha chain, C-terminal [IPR010579] 0.8466989069505775 1.599565216742577 0.1096950699964272 1.0 0.2864677699344775 3 P01889 1
20
+ MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.8466989069505775 1.599565216742577 0.1096950699964272 1.0 0.2864677699344775 3 P01889 1
21
+ Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394] 0.5796767799374812 1.5918909564337944 0.11140920792884 1.0 0.2888963166497388 16 Q9UPU5,Q70CQ2,Q96K76,O94966 4
22
+ Ubiquitin specific protease domain [IPR028889] 0.5796767799374812 1.5918909564337944 0.11140920792884 1.0 0.2888963166497388 16 Q9UPU5,Q70CQ2,Q96K76,O94966 4
23
+ Rho GTPase-activating protein domain [IPR000198] 0.6931879895753539 1.5702948801260703 0.1163465247524158 1.0 0.2969982322964968 7 Q13459,Q9NRY4 2
24
+ Thiamine pyrophosphate enzyme, central domain [IPR012000] 0.9289747399702823 1.5594905241657095 0.1188803256145409 1.0 0.3009833698513605 2 A1L0T0 1
25
+ Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001] 0.9289747399702823 1.5594905241657095 0.1188803256145409 1.0 0.3009833698513605 2 A1L0T0 1
26
+ Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766] 0.9289747399702823 1.5594905241657095 0.1188803256145409 1.0 0.3009833698513605 2 A1L0T0 1
27
+ SET domain [IPR001214] 0.6081622447885972 1.5468489479099496 0.1218996739400544 1.0 0.3033763020370169 12 Q8WTS6,Q9H7B4 2
28
+ Peptidase S9A, N-terminal domain [IPR023302] 0.923922734026746 1.5396375185225577 0.1236487347869621 1.0 0.3060993123392796 2 P48147 1
29
+ Homeobox domain [IPR001356] 0.7300533452374425 1.4406748509178462 0.1496765630492413 1.0 0.3449697003348606 5 Q99626,P37275,Q96G23 3
30
+ Histone H2A/H2B/H3 [IPR007125] 0.804696789536261 1.4404359529101511 0.1497440980120776 1.0 0.3449697003348606 3 P16104,O75367 2
31
+ Histone H2A, C-terminal domain [IPR032454] 0.804696789536261 1.4404359529101511 0.1497440980120776 1.0 0.3449697003348606 3 P16104,O75367 2
32
+ PIN domain [IPR002716] 0.7682048019171527 1.3016335135133643 0.1930416976339439 1.0 0.3994712907494571 3 Q9ULX3 1
33
+ Band 7 domain [IPR001107] 0.6261313227355964 1.2841486155591932 0.1990899603941442 1.0 0.4079952462823339 7 P27105,Q14254 2
34
+ Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403] 0.6229202507950886 1.2703540409394236 0.2039585463990403 1.0 0.4161352027262471 7 Q96Q15 1
35
+ Saposin B type domain [IPR008139] 0.8523031203566126 1.2583524286650047 0.2082643280328922 1.0 0.4209115773378844 2 Q9Y2B0 1
36
+ Immunoglobulin C1-set [IPR003597] 0.6836685341399433 1.256686709477527 0.2088671025760398 1.0 0.4215180294741093 5 P55899,P01889 2
37
+ Proteasome activator PA28, C-terminal domain [IPR003186] 0.751127678107596 1.2366684915586883 0.2162101808320335 1.0 0.4297968262792387 3 P61289 1
38
+ Proteasome activator PA28, N-terminal domain [IPR003185] 0.751127678107596 1.2366684915586883 0.2162101808320335 1.0 0.4297968262792387 3 P61289 1
39
+ TATA box binding protein associated factor (TAF) [IPR004823] 0.7425683709869132 1.2041366350290128 0.2285367721799023 1.0 0.4432276535661754 3 P62805,Q9Y6J9 2
40
+ Peptidase M16, N-terminal [IPR011765] 0.5889413047809284 1.1242295668500908 0.2609156493487938 1.0 0.4758545077662581 7 Q5JRX3,Q10713 2
41
+ Peptidase M16, C-terminal [IPR007863] 0.5889413047809284 1.1242295668500908 0.2609156493487938 1.0 0.4758545077662581 7 Q5JRX3,Q10713 2
42
+ Ribosomal protein L7, eukaryotic/archaeal [IPR035808] 0.817830609212482 1.1240446261317358 0.2609940946729288 1.0 0.4758545077662581 2 Q6DKI1 1
43
+ Ribosomal protein L30, N-terminal [IPR012988] 0.817830609212482 1.1240446261317358 0.2609940946729288 1.0 0.4758545077662581 2 Q6DKI1 1
44
+ Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375] 0.6993326166244525 1.1137426740280476 0.2653895963118726 1.0 0.4794330213115034 4 P48147 1
45
+ Peptidase M3A/M3B catalytic domain [IPR001567] 0.8095096582466572 1.0918528778652947 0.2748977726442998 1.0 0.4882591178663106 2 Q9BYT8 1
46
+ Core histone macro-H2A, macro domain [IPR035796] 0.804457652303121 1.072362923624527 0.2835570542548211 1.0 0.4924421118641294 2 O75367 1
47
+ EF-hand domain [IPR002048] 0.3993110242962352 1.0643221939486114 0.2871827672289044 1.0 0.4943732191509518 42 P80303,O75071,Q9Y680,Q02818 4
48
+ N-acetylgalactosaminyltransferase [IPR045885] 0.7042211652794214 1.058960430194977 0.2896178010385435 1.0 0.4948389243372727 3 Q10471,Q10472 2
49
+ Brix domain [IPR007109] 0.6308766158206672 1.0471996424651804 0.2950075101645932 1.0 0.4998909672987958 5 Q8TDN6,Q9H7B2 2
50
+ Putative WW-binding domain and destruction box [IPR033461] 0.7866270430906397 1.0039596057700115 0.3153980842316946 1.0 0.520061376308626 2 Q9ULX3 1
51
+ LIS1 homology motif [IPR006594] 0.4875283824088037 0.9973730582347816 0.3185834636625417 1.0 0.5234542456048253 13 Q96S59,Q9Y4B6,Q9UL63,Q14978,Q14207 5
52
+ 3'-5' exonuclease domain [IPR002562] 0.6834126040428001 0.9808562316505812 0.3266636437876444 1.0 0.5320332054742323 3 Q14191,Q9NVH0 2
53
+ Importin-beta, N-terminal domain [IPR001494] 0.4832292066764242 0.9755163117953564 0.3293042144386038 1.0 0.5327208442333857 13 O15397 1
54
+ Sec24-like, trunk domain [IPR041742] 0.681514952425163 0.973767178242696 0.3301721532400674 1.0 0.5327208442333857 3 O95487 1
55
+ GINS subunit, domain A [IPR021151] 0.6776632115518848 0.9593981105400642 0.3373582266022454 1.0 0.5390376713065138 3 Q9BRX5 1
56
+ Chromo domain [IPR023780] 0.5402280724359008 0.9556955638302362 0.3392260644112421 1.0 0.5402091598454426 8 Q14781 1
57
+ Tim44-like domain [IPR007379] 0.7705794947994064 0.9430034939693612 0.3456791157752805 1.0 0.5476202146951971 2 Q9BRJ2 1
58
+ Ovarian carcinoma immunoreactive antigen domain [IPR009764] 0.7702823179791984 0.9418808860339511 0.3462536270785121 1.0 0.5479070178486684 2 Q9NX40 1
59
+ Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.7679049034175343 0.9329087480372772 0.3508670852265965 1.0 0.5522509838228998 2 O60506 1
60
+ Ricin B, lectin domain [IPR000772] 0.6484528736016048 0.922647948947069 0.3561906993827586 1.0 0.5563775457681521 4 Q10471,Q10472 2
61
+ GHMP kinase, C-terminal domain [IPR013750] 0.7625557206537898 0.9127798796287792 0.3613583223886074 1.0 0.5619111824970807 2 Q03426 1
62
+ CRAL-TRIO lipid binding domain [IPR001251] 0.6599277002221129 0.8936207585235121 0.3715248358098377 1.0 0.5738750236996107 3 O75962 1
63
+ DNA mismatch repair protein, S5 domain 2-like [IPR013507] 0.6568690006180578 0.8823484200937021 0.3775884196031973 1.0 0.577239005280127 3 P54278 1
64
+ DNA mismatch repair protein family, N-terminal [IPR002099] 0.6568690006180578 0.8823484200937021 0.3775884196031973 1.0 0.577239005280127 3 P54278 1
65
+ RNA-binding S4 domain [IPR002942] 0.6495243757431561 0.855378312675565 0.3923417458354816 1.0 0.5871422687543344 3 Q9NV31,P46781 2
66
+ Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955] 0.7465081723625566 0.8529228507315236 0.3937020888430984 1.0 0.5879143793179781 2 Q15120 1
67
+ Histidine kinase domain [IPR005467] 0.7465081723625566 0.8529228507315236 0.3937020888430984 1.0 0.5879143793179781 2 Q15120 1
68
+ ELM2 domain [IPR000949] 0.6486325802615861 0.8521133657028069 0.3941511743714647 1.0 0.5882695716101443 3 Q9UKL0,O94776 2
69
+ TAF6, C-terminal HEAT repeat domain [IPR011442] 0.7423476968796443 0.8375461102323866 0.4022856697438968 1.0 0.5965950408633784 2 Q9Y6J9 1
70
+ Guanylate-binding protein/Atlastin, C-terminal [IPR003191] 0.740564635958396 0.8309753076701247 0.4059875786820341 1.0 0.5990673505548212 2 Q6DD88 1
71
+ Guanylate-binding protein, N-terminal [IPR015894] 0.740564635958396 0.8309753076701247 0.4059875786820341 1.0 0.5990673505548212 2 Q6DD88 1
72
+ GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386] 0.740564635958396 0.8309753076701247 0.4059875786820341 1.0 0.5990673505548212 2 Q6DD88 1
73
+ Zinc finger, double-stranded RNA binding [IPR022755] 0.5734755905505693 0.8228181682335483 0.4106114033426875 1.0 0.6032721200482237 5 Q5F1R6,Q9ULV3,Q9H3H1 3
74
+ Zinc finger, CHHC-type [IPR012996] 0.638515373700272 0.8152334680370256 0.4149386839050599 1.0 0.605497194087502 3 P55795 1
75
+ Dynein heavy chain, AAA module D4 [IPR024317] 0.7340267459138194 0.8069851989723786 0.4196750105702667 1.0 0.605497194087502 2 Q8NCM8 1
76
+ Dynein heavy chain, coiled coil stalk [IPR024743] 0.7340267459138194 0.8069851989723786 0.4196750105702667 1.0 0.605497194087502 2 Q8NCM8 1
77
+ Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699] 0.7340267459138194 0.8069851989723786 0.4196750105702667 1.0 0.605497194087502 2 Q8NCM8 1
78
+ Dynein heavy chain, linker [IPR013602] 0.7340267459138194 0.8069851989723786 0.4196750105702667 1.0 0.605497194087502 2 Q8NCM8 1
79
+ Dynein heavy chain, tail [IPR013594] 0.7340267459138194 0.8069851989723786 0.4196750105702667 1.0 0.605497194087502 2 Q8NCM8 1
80
+ Dynein heavy chain, C-terminal domain [IPR041228] 0.7340267459138194 0.8069851989723786 0.4196750105702667 1.0 0.605497194087502 2 Q8NCM8 1
81
+ Dynein heavy chain AAA lid domain [IPR041658] 0.7340267459138194 0.8069851989723786 0.4196750105702667 1.0 0.605497194087502 2 Q8NCM8 1
82
+ Dynein heavy chain region D6 P-loop domain [IPR004273] 0.7340267459138194 0.8069851989723786 0.4196750105702667 1.0 0.605497194087502 2 Q8NCM8 1
83
+ Dynein heavy chain, ATP-binding dynein motor region [IPR035706] 0.7340267459138194 0.8069851989723786 0.4196750105702667 1.0 0.605497194087502 2 Q8NCM8 1
84
+ Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.5326445676417925 0.8013354904841811 0.4229374499653091 1.0 0.60740392260246 6 Q9UMX5,O15173 2
85
+ Sec63 domain [IPR004179] 0.6218787158144984 0.7553013882605659 0.4500681659022612 1.0 0.6289626013190416 3 Q8N3C0,Q9UGP8 2
86
+ PTB/PI domain [IPR006020] 0.6004306362989997 0.7469579875796035 0.4550889211393987 1.0 0.6306442962516674 4 Q9UKG1 1
87
+ Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263] 0.7170876671619623 0.7456441572638979 0.4558824008936577 1.0 0.6313438520580988 2 P42356 1
88
+ Fork head domain [IPR001766] 0.7150074294205062 0.7381987531306733 0.4603936804710813 1.0 0.6356947943043935 2 P85037 1
89
+ Class I myosin, motor domain [IPR036072] 0.5812340334340069 0.6788260252884055 0.4972481016571595 1.0 0.6535327810831473 4 O94832,O43795 2
90
+ Class I myosin tail homology domain [IPR010926] 0.5812340334340069 0.6788260252884055 0.4972481016571595 1.0 0.6535327810831473 4 O94832,O43795 2
91
+ GCF, C-terminal [IPR022783] 0.5978734430313556 0.6707045450793784 0.5024087668507113 1.0 0.6553669394282112 3 Q9Y5B6 1
92
+ CTLH/CRA C-terminal to LisH motif domain [IPR024964] 0.5967830442159048 0.6669224726434192 0.5048216556124356 1.0 0.6557501450002954 3 Q96S59 1
93
+ CRA domain [IPR013144] 0.5967830442159048 0.6669224726434192 0.5048216556124356 1.0 0.6557501450002954 3 Q96S59 1
94
+ K Homology domain [IPR004087] 0.379962623030959 0.6458869102010011 0.5183525974353016 1.0 0.6678245146626804 25 P61978,Q9Y2W6,O75179,O75525,Q92667,Q96AE4,Q13601,Q96PU8,Q15637,Q9Y6M1 10
95
+ Protein phosphatase 1 binding domain [IPR029334] 0.6858841010401199 0.6362822510863932 0.5245924713036421 1.0 0.6714108605609573 2 Q69YH5 1
96
+ Ribosomal protein S4/S9, N-terminal [IPR001912] 0.6843982169390798 0.6312094033079597 0.5279036143828719 1.0 0.6751384915020991 2 Q9NV31 1
97
+ MIRO domain [IPR020860] 0.6781575037147113 0.6100515664980057 0.5418276489409777 1.0 0.6818752834616462 2 Q8IXI1 1
98
+ EF hand associated, type-1 [IPR013566] 0.6781575037147113 0.6100515664980057 0.5418276489409777 1.0 0.6818752834616462 2 Q8IXI1 1
99
+ EF hand associated, type-2 [IPR013567] 0.6781575037147113 0.6100515664980057 0.5418276489409777 1.0 0.6818752834616462 2 Q8IXI1 1
100
+ Sec23/Sec24 beta-sandwich [IPR012990] 0.515525986783075 0.6060334118369428 0.5444925665647344 1.0 0.6821465577520403 5 O95487 1
101
+ Sec23/Sec24, helical domain [IPR006900] 0.515525986783075 0.6060334118369428 0.5444925665647344 1.0 0.6821465577520403 5 O95487 1
102
+ Zinc finger, Sec23/Sec24-type [IPR006895] 0.515525986783075 0.6060334118369428 0.5444925665647344 1.0 0.6821465577520403 5 O95487 1
103
+ Sec23/Sec24, trunk domain [IPR006896] 0.515525986783075 0.6060334118369428 0.5444925665647344 1.0 0.6821465577520403 5 O95487 1
104
+ CTLH, C-terminal LisH motif [IPR006595] 0.4791644728689515 0.5918430639008913 0.5539556830898267 1.0 0.6851659480119018 6 Q9UL63,Q96S59 2
105
+ Replication factor C, C-terminal [IPR013748] 0.5742853649208846 0.5902525873437142 0.5550213209029984 1.0 0.6851659480119018 3 P35250 1
106
+ EF-hand, Ca insensitive [IPR014837] 0.5722354340071245 0.5834061389025949 0.5596199261861932 1.0 0.6871043732630343 3 O43707,P12814 2
107
+ Nit1/2, carbon-nitrogen hydrolase domain [IPR045254] 0.6665676077265984 0.5714247927894933 0.5677117269682204 1.0 0.6928441798818048 2 Q86X76 1
108
+ Carbon-nitrogen hydrolase [IPR003010] 0.6665676077265984 0.5714247927894933 0.5677117269682204 1.0 0.6928441798818048 2 Q86X76 1
109
+ Pleckstrin homology domain [IPR001849] 0.3534199423811383 0.5577878209309031 0.5769892801960559 1.0 0.6978059892352525 32 Q13464,Q96TA1,Q92974,Q96JJ3,P31751,O75962,Q15057,Q9UQ16,Q9UKG1,Q9H4L5 10
110
+ NSD, Cys-His rich domain [IPR041306] 0.5509100838896157 0.5137539413164911 0.6074240335786685 1.0 0.7202425773942946 3 O96028 1
111
+ Metastasis-associated protein MTA1, R1 domain [IPR035170] 0.6484398216939091 0.5129022040036897 0.6080197316404718 1.0 0.7205680649441336 2 O94776 1
112
+ LEM-like domain [IPR013146] 0.6469539375928688 0.508215198224817 0.6113024335259525 1.0 0.7232273905564051 2 P42167 1
113
+ Beta-Casp domain [IPR022712] 0.5295095411188153 0.5042881306845945 0.6140589170171016 1.0 0.7246415609714525 4 Q9NV88 1
114
+ Tudor domain [IPR002999] 0.4114373876076596 0.4975198826452644 0.6188224855353233 1.0 0.7269245349164849 10 Q9Y2W6,Q14739 2
115
+ Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750] 0.6303120356612196 0.4569499118699999 0.6477070476885918 1.0 0.7481808908389581 2 Q8IU81 1
116
+ BTB/Kelch-associated [IPR011705] 0.6273402674591395 0.448043176450738 0.6541220363894165 1.0 0.7537152963775444 2 Q08380 1
117
+ Helicase/SANT-associated domain [IPR014012] 0.5281115936426722 0.4428656143560849 0.6578629402277252 1.0 0.7573990444539953 3 Q96L91 1
118
+ Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164] 0.6231797919762271 0.435705774775537 0.663050215370327 1.0 0.7592906454795891 2 O94973 1
119
+ Peptidase M16, middle/third domain [IPR032632] 0.6202080237741469 0.4269894243587124 0.669387030615908 1.0 0.7646607384189105 2 P14735 1
120
+ FYVE zinc finger [IPR000306] 0.4627662196214175 0.4250275607114347 0.6708165835475282 1.0 0.7653519808192814 5 Q9P2R3,Q15075 2
121
+ Zinc finger, FYVE-related [IPR017455] 0.4627662196214175 0.4250275607114347 0.6708165835475282 1.0 0.7653519808192814 5 Q9P2R3,Q15075 2
122
+ Aminopeptidase P, N-terminal [IPR007865] 0.6181277860326906 0.4209364160557593 0.6738015126380656 1.0 0.7684427570421838 2 Q9NQH7 1
123
+ LEM domain [IPR003887] 0.4590109622197371 0.4129815681527173 0.6796201180348982 1.0 0.7738111319407978 5 P50402 1
124
+ ABC transporter type 1, transmembrane domain [IPR011527] 0.4970216033934201 0.403781209217749 0.6863736155918683 1.0 0.7792704930384644 4 Q9NRK6 1
125
+ Ribosomal L28e/Mak16 [IPR029004] 0.6118870728083221 0.4030215176042634 0.6869323950558097 1.0 0.7795870905584474 2 Q9BXY0 1
126
+ rRNA-processing arch domain [IPR025696] 0.6112927191679062 0.401334728739065 0.6881736979738475 1.0 0.7800422258270922 2 Q15477 1
127
+ ATP-dependent RNA helicase Ski2, C-terminal [IPR012961] 0.6112927191679062 0.401334728739065 0.6881736979738475 1.0 0.7800422258270922 2 Q15477 1
128
+ 3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176] 0.61069836552749 0.3996513546418383 0.6894133260307362 1.0 0.7808117580299311 2 Q16836 1
129
+ 3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108] 0.61069836552749 0.3996513546418383 0.6894133260307362 1.0 0.7808117580299311 2 Q16836 1
130
+ EB1, C-terminal [IPR004953] 0.6032689450222896 0.3789013832585431 0.7047610969699276 1.0 0.7946395364620439 2 Q15691 1
131
+ ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.6026745913818735 0.3772650857345864 0.7059766159964425 1.0 0.7956879302104785 2 Q9NVI7 1
132
+ AWS domain [IPR006560] 0.4860398710690383 0.3718141765881601 0.7100312078342219 1.0 0.7979971403625132 4 O96028 1
133
+ Chromo/chromo shadow domain [IPR000953] 0.3767205750619109 0.3595314731462442 0.7191975374206612 1.0 0.8056979652922531 10 Q14781 1
134
+ PIK-related kinase, FAT [IPR003151] 0.4976463531216951 0.3549951413702042 0.7225932311226675 1.0 0.808851345931121 3 P42345 1
135
+ Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091] 0.3917098645426905 0.3536453042172226 0.7236047177213467 1.0 0.8096581514077745 8 O15254,P49748 2
136
+ Zinc finger C2H2 AKAP95-type [IPR034736] 0.4914444128897807 0.3381899726405908 0.7352200318265032 1.0 0.8203566193484687 3 Q9ULX6 1
137
+ cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117] 0.5863298662704322 0.3336944503716921 0.7386101377460557 1.0 0.823470469824966 2 P10644 1
138
+ Tubulin/FtsZ, GTPase domain [IPR003008] 0.3903763496647924 0.3306227640781026 0.7409294491187797 1.0 0.8247002361799737 7 P04350,P07437 2
139
+ Tubulin/FtsZ, 2-layer sandwich domain [IPR018316] 0.3903763496647924 0.3306227640781026 0.7409294491187797 1.0 0.8247002361799737 7 P04350,P07437 2
140
+ Suppressor of forked [IPR008847] 0.5818722139673118 0.3223042360302464 0.7472222243386044 1.0 0.830744069773658 2 Q12996 1
141
+ Immunoglobulin I-set [IPR013098] 0.4806655438175651 0.3099304584385602 0.7566138399947664 1.0 0.8395097786396113 3 O75962 1
142
+ WWE domain [IPR004170] 0.4797859690844105 0.3076790478930563 0.7583265641864003 1.0 0.8407402393547472 3 Q7Z6Z7,Q7Z2W4 2
143
+ Transcription termination and cleavage factor, C-terminal domain [IPR026896] 0.5708766716196151 0.2951484948690716 0.7678804453126904 1.0 0.8496412555406606 2 Q9H0L4 1
144
+ Cleavage stimulation factor subunit 2, hinge domain [IPR025742] 0.5708766716196151 0.2951484948690716 0.7678804453126904 1.0 0.8496412555406606 2 Q9H0L4 1
145
+ Glutathione S-transferase, C-terminal-like [IPR010987] 0.3429282199459179 0.2922649140119366 0.7700840827853273 1.0 0.8514030053819518 12 P78417,Q9Y696 2
146
+ Myotubularin-like phosphatase domain [IPR010569] 0.4550630593454862 0.2880124609916559 0.7733372001508048 1.0 0.8539825941395683 4 Q13614 1
147
+ 26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135] 0.5607726597325424 0.2714081380226624 0.7860771436341214 1.0 0.8666765023836216 2 Q13098 1
148
+ Immunoglobulin-like domain [IPR007110] 0.326041080222901 0.2680335642854504 0.788673483098973 1.0 0.8674785349252132 14 P55899,Q9Y624,O75962,P01889 4
149
+ 2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078] 0.4625445897740661 0.2652822442525383 0.7907920416822707 1.0 0.8691222715410907 3 P11182,P36957 2
150
+ Metallo-beta-lactamase [IPR001279] 0.4069476128226159 0.2609628062317844 0.7941211899577258 1.0 0.8710687559810208 5 Q9NV88 1
151
+ DNA2/NAM7 helicase-like, C-terminal [IPR041679] 0.4439488551888289 0.2604588596635575 0.7945098456396893 1.0 0.8710687559810208 4 Q9HCE1,P42694,O60306 3
152
+ ABC transporter-like, ATP-binding domain [IPR003439] 0.3675905453520224 0.2589324030579824 0.7956873965144684 1.0 0.8714075498595338 7 Q9NRK6 1
153
+ Major facilitator superfamily domain [IPR020846] 0.4585373835175928 0.2559152627707484 0.7980162689945611 1.0 0.8732712413162487 3 P11166 1
154
+ ERM family, FERM domain C-lobe [IPR041789] 0.4551129607609868 0.248060386285492 0.8040876849878809 1.0 0.8792242648964461 3 P26038,P35241 2
155
+ Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420] 0.5488855869242215 0.2450139734446621 0.8064456118254919 1.0 0.8803008186133171 2 A0AVT1 1
156
+ Ubiquitin-activating enzyme, SCCH domain [IPR019572] 0.5488855869242215 0.2450139734446621 0.8064456118254919 1.0 0.8803008186133171 2 A0AVT1 1
157
+ Ubiquitin-activating enzyme E1, C-terminal [IPR018965] 0.5488855869242215 0.2450139734446621 0.8064456118254919 1.0 0.8803008186133171 2 A0AVT1 1
158
+ Ubiquitin-activating enzyme E1, FCCH domain [IPR032418] 0.5488855869242215 0.2450139734446621 0.8064456118254919 1.0 0.8803008186133171 2 A0AVT1 1
159
+ La-type HTH domain [IPR006630] 0.3955978584176182 0.2320614350041581 0.8164902976816064 1.0 0.8879873734330375 5 Q92615,Q6PKG0,P05455,Q71RC2 4
160
+ Transcription elongation factor S-II, central domain [IPR003618] 0.4444114149821564 0.2244202466993588 0.8224303178511456 1.0 0.8933184224709207 3 Q9BTC0,P23193 2
161
+ Rhodanese-like domain [IPR001763] 0.3919896001142611 0.2232273356852388 0.823358577860084 1.0 0.8933487026194841 5 Q99956 1
162
+ DNA2/NAM7 helicase, helicase domain [IPR041677] 0.4438168846611074 0.2231477580766963 0.8234205097393892 1.0 0.8933487026194841 3 P42694,O60306 2
163
+ Helicase/UvrB, N-terminal [IPR006935] 0.4438168846611039 0.2231477580766886 0.8234205097393952 1.0 0.8933487026194841 3 Q9UPY3,P19447 2
164
+ TRASH domain [IPR011017] 0.3603353822976008 0.2056470144853908 0.8370666500954254 1.0 0.9037121078164924 6 Q5VZL5,P83731,Q5SVZ6 3
165
+ RBM1CTR [IPR012604] 0.528380386329868 0.2035073428884341 0.8387385069729845 1.0 0.9050316706391948 2 P38159 1
166
+ Glutathione S-transferase, C-terminal [IPR004046] 0.3291301901711559 0.1962364973067903 0.8444250626534566 1.0 0.9104607659778852 10 P78417,P07814 2
167
+ von Willebrand factor, type A [IPR002035] 0.3563585735085508 0.195685124547673 0.844856628202934 1.0 0.9104607659778852 6 Q96SY0 1
168
+ Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.4280618311533769 0.1910278583573685 0.8485037672318356 1.0 0.912683816741764 3 Q00839,Q1KMD3 2
169
+ Histidine kinase/HSP90-like ATPase [IPR003594] 0.3393867222387532 0.1898393852345665 0.8494349920986184 1.0 0.912683816741764 8 P07900,Q12931,P14625,P08238,Q15118,Q02880,Q15120 7
170
+ mRNA splicing factor Cwf21 domain [IPR013170] 0.5176820208023791 0.1839153291809841 0.8540798789898256 1.0 0.9162605789625056 2 O15042 1
171
+ SGS domain [IPR007699] 0.5150074294205069 0.1792402961397946 0.8577490242875538 1.0 0.918781166400322 2 Q9Y2Z0 1
172
+ Zinc finger, RanBP2-type [IPR001876] 0.3350670773073291 0.1781851572052404 0.8585775660242965 1.0 0.9193150793455078 8 P35637,Q92804 2
173
+ Potentiating neddylation domain [IPR005176] 0.5126300148588426 0.1751596608449568 0.8609541802292677 1.0 0.9215055311062684 2 Q96GG9 1
174
+ Glycosyltransferase 2-like [IPR001173] 0.3988498161325773 0.1639295377688603 0.8697866138624768 1.0 0.9295302070633148 4 Q10471 1
175
+ Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152] 0.3273905020493298 0.1510997115327731 0.8798970600516096 1.0 0.9376138354693294 7 O94973,Q9UJY5,O43747 3
176
+ OBG-type guanine nucleotide-binding (G) domain [IPR031167] 0.3883437407077067 0.1451669088407221 0.8845790920569019 1.0 0.9406463426416464 4 Q9BZE4,P55039,Q9NTK5 3
177
+ Heat shock protein Hsp90, N-terminal [IPR020575] 0.3806125483199611 0.1322847485580938 0.8947590702450581 1.0 0.9496585406373806 4 Q12931,P14625,P08238 3
178
+ Sterile alpha motif domain [IPR001660] 0.3182828596596153 0.1303574876975198 0.8962835994263898 1.0 0.9501902643328876 7 Q5PRF9 1
179
+ Far upstream element-binding protein, C-terminal [IPR015096] 0.4823179791976243 0.1292748696106033 0.8971401557025205 1.0 0.9507051892665656 2 Q96AE4 1
180
+ Ribosomal protein L26/L24, KOW domain [IPR041988] 0.4820208023774163 0.1288807056180055 0.8974520440150093 1.0 0.9507051892665656 2 P61254 1
181
+ Sec23, C-terminal [IPR037550] 0.4787518573551279 0.124614842310011 0.9008284775307204 1.0 0.9521090360239304 2 Q15436 1
182
+ GHMP kinase N-terminal domain [IPR006204] 0.3871231070925396 0.1223604035051963 0.9026135962407632 1.0 0.952592004100874 3 Q03426 1
183
+ CID domain [IPR006569] 0.3426531826293804 0.1207682490289942 0.903874599593899 1.0 0.9531581824570272 5 Q96P16,Q5VT52,O15042,Q8IWX8 4
184
+ Asparagine synthase [IPR001962] 0.4751857355126317 0.1201065633620695 0.9043987332206884 1.0 0.9533499137091662 2 P08243 1
185
+ SWAP/Surp [IPR000061] 0.3180601011603749 0.1124099485356654 0.9104983675336868 1.0 0.957243470585624 6 O15042,Q15459,Q8IWX8,Q12872,Q8IX01 5
186
+ Peripheral subunit-binding domain [IPR004167] 0.4624071322436869 0.1051750082068813 0.9162369412785648 1.0 0.95965396068477 2 P11182 1
187
+ Chromo domain subgroup [IPR017984] 0.3700951248513607 0.1000980796503684 0.92026645989378 1.0 0.9606990223676096 3 P45973,Q13185 2
188
+ Chromo shadow domain [IPR008251] 0.3700951248513607 0.1000980796503684 0.92026645989378 1.0 0.9606990223676096 3 P45973,Q13185 2
189
+ Ribosomal protein L30, ferredoxin-like fold domain [IPR016082] 0.3691350545717019 0.098950262549325 0.9211777609469912 1.0 0.9606990223676096 3 Q6DKI1 1
190
+ Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872] 0.45438335809807 0.0967506733439932 0.9229243970456352 1.0 0.9606990223676096 2 Q96GW9 1
191
+ Methionyl/Leucyl tRNA synthetase [IPR015413] 0.45438335809807 0.0967506733439932 0.9229243970456352 1.0 0.9606990223676096 2 Q96GW9 1
192
+ Methioninyl-tRNA synthetase core domain [IPR033911] 0.45438335809807 0.0967506733439932 0.9229243970456352 1.0 0.9606990223676096 2 Q96GW9 1
193
+ Gelsolin-like domain [IPR007123] 0.3092975594738248 0.0966921928429501 0.9229708399879692 1.0 0.9606990223676096 6 O95487 1
194
+ Dbl homology (DH) domain [IPR000219] 0.308165977673584 0.0947542105445504 0.924510057850754 1.0 0.961449033276456 6 O75962,Q92974 2
195
+ HECT domain [IPR000569] 0.2811255340012011 0.0868476633479389 0.930792600847706 1.0 0.9668994380309068 11 Q96PU5,Q5GLZ8,P46934,Q15386 4
196
+ CSN8/PSMD8/EIF3K [IPR033464] 0.3552318668251967 0.0835756319724466 0.9333938420063596 1.0 0.9688788110278465 3 P48556,Q9UBQ5 2
197
+ FKBP3, basic tilted helix bundle domain [IPR041200] 0.4332838038633005 0.0778994691399997 0.937908021694215 1.0 0.9709098516426884 2 Q00688 1
198
+ AP complex, mu/sigma subunit [IPR022775] 0.29142475617783 0.0776508323763379 0.9381058060269992 1.0 0.9709098516426884 7 P53680 1
199
+ Ribosome receptor lysine/proline rich [IPR007794] 0.4294205052005962 0.0749373338941475 0.9402645719013676 1.0 0.9716628636293548 2 Q86UP2 1
200
+ JAB1/MPN/MOV34 metalloenzyme domain [IPR000555] 0.2878065217103335 0.0722224640977226 0.9424248680891374 1.0 0.9724539672575946 8 O15372,Q6P2Q9,O95630,Q92905 4
201
+ K Homology domain, type 1 [IPR004088] 0.2659414923645892 0.0675056571343786 0.9461791585589144 1.0 0.9752438773451432 26 P61978,Q9Y2W6,O75179,O75525,Q92667,Q96AE4,Q96PU8,Q15637,Q9Y6M1 9
202
+ Nucleoside diphosphate kinase-like domain [IPR034907] 0.3202648521452239 0.0580647894848946 0.9536970209727396 1.0 0.9811770237935278 4 Q13232 1
203
+ Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573] 0.3922734026745932 0.0531990774086965 0.9575732906974056 1.0 0.9844376576568016 2 P21399 1
204
+ Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030] 0.3922734026745932 0.0531990774086965 0.9575732906974056 1.0 0.9844376576568016 2 P21399 1
205
+ GTP binding protein, second domain [IPR031662] 0.388112927191681 0.0514369841744974 0.9589773146561968 1.0 0.9855172772389328 2 P55039 1
206
+ SANT/Myb domain [IPR001005] 0.2602714414615851 0.0454821830815515 0.9637229760424342 1.0 0.9887240620834168 12 Q96L91,P28370 2
207
+ Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543] 0.3676077265973273 0.04436560163907 0.964612980552793 1.0 0.9887240620834168 2 Q13555 1
208
+ CBS domain [IPR000644] 0.2722496582759743 0.0439580010707526 0.9649378817747674 1.0 0.9887240620834168 6 P51798,P20839,P54619,Q8NE01 4
209
+ Nucleotidyl transferase domain [IPR005835] 0.2984542211652738 0.0424794502710724 0.9661164932691706 1.0 0.9890186787341724 3 Q96IJ6,Q9Y5P6 2
210
+ AARP2CN [IPR012948] 0.3515601783060942 0.040427261711458 0.9677524963078368 1.0 0.989060808153147 2 Q14692 1
211
+ Bms1/Tsr1-type G domain [IPR030387] 0.3515601783060942 0.040427261711458 0.9677524963078368 1.0 0.989060808153147 2 Q14692 1
212
+ Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034] 0.3515601783060942 0.040427261711458 0.9677524963078368 1.0 0.989060808153147 2 Q14692 1
213
+ Pleckstrin homology domain 9 [IPR041681] 0.3462109955423497 0.0393727533138567 0.968593202765386 1.0 0.9890635880139608 2 O15020 1
214
+ Pleckstrin homology domain, spectrin-type [IPR001605] 0.3462109955423497 0.0393727533138567 0.968593202765386 1.0 0.9890635880139608 2 O15020 1
215
+ Ribosomal protein L11, N-terminal [IPR020784] 0.3352154531946528 0.0375505484467218 0.9700460367095318 1.0 0.9890635880139608 2 Q9Y3B7 1
216
+ Ribosomal protein L11, C-terminal [IPR020783] 0.3352154531946528 0.0375505484467218 0.9700460367095318 1.0 0.9890635880139608 2 Q9Y3B7 1
217
+ 3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154] 0.3286775631500763 0.0366620821692094 0.970754442349661 1.0 0.9890635880139608 2 Q49A26 1
218
+ Major sperm protein (MSP) domain [IPR000535] 0.2838217263662918 0.0365408441745667 0.9708511114997782 1.0 0.9890635880139608 3 Q9P0L0 1
219
+ Rap/Ran-GAP domain [IPR000331] 0.3194650817236276 0.0356220326393454 0.9715837399634366 1.0 0.9890635880139608 2 Q6GYQ0 1
220
+ Dilute domain [IPR002710] 0.3040118870728105 0.0343375819770175 0.972607956444996 1.0 0.9890635880139608 2 P55196 1
221
+ Kinesin motor domain [IPR001752] 0.2501320110029985 0.0304404116302572 0.9757158159566528 1.0 0.9910169757254844 15 Q2M1P5 1
222
+ Bromo adjacent homology (BAH) domain [IPR001025] 0.2717811477847257 0.0279542234266855 0.9776986612776136 1.0 0.9923071325284816 4 Q13330,P26358,O94776 3
223
+ SMCs flexible hinge [IPR010935] 0.2323022010707834 0.013180348665094 0.9894839077737164 1.0 0.9991706610405366 5 O95347,A6NHR9,Q9UQE7,Q9NTJ3 4
interpro_domain/selections.json ADDED
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interpro_family/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Syntaxin [IPR045242]"}
interpro_family/advanced/plot_0.png ADDED

Git LFS Details

  • SHA256: de93e06c90235f394176c19239148267066d20a0425da8cba3e82b39d0d9af03
  • Pointer size: 131 Bytes
  • Size of remote file: 178 kB
interpro_family/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Syntaxin [IPR045242]"}
interpro_family/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: e7f3f1324771259cf39cdb5bbe92ab2abc9406ef3b0825538978943a06be75c3
  • Pointer size: 131 Bytes
  • Size of remote file: 129 kB
interpro_family/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
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+ oid sha256:702c3e9d9ca2dee60188f9968b5eeb92c729d522f59957dd3c70adfbdbee4cc5
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+ size 481269
interpro_family/df_merge.tsv ADDED
@@ -0,0 +1,5 @@
 
 
 
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Proteasome, subunit alpha/beta [IPR001353] 4 14 2.4589562079708243 0.0139341613472607 5.075242718446602 13.970873786407768 1.2284854682369022 0.3020132543529001 2.3027355385508845 0.1681602725795027 1.1101966392985694 0.3179790146746512 1.0 0.0026008925831016 0.000453663444764 2.923978855186412e-05 6.933879980949677e-05
3
+ Proteasome B-type subunit [IPR023333] 3 7 2.145015118190225 0.0319516382494429 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 1.0 0.0007972103198291 7.149857972393559e-05 3.972711663948022e-05 2.915330495677531e-05
4
+ Syntaxin [IPR045242] 5 6 2.044770150109221 0.0408775239149696 2.674757281553398 5.815533980582524 0.7134969984167514 0.3462495636510407 1.4434464182805606 1.4295601388514203 1.142372356309129 0.3001529293380739 1.0 1.0 1.0 0.0042908003473226 0.0003776201815095
5
+ Linker histone H1/H5 [IPR005819] 2 5 2.0049157341141397 0.0449720563395126 4.014563106796117 4.956310679611651 -1.4175513233889876 0.1832168833940027 1.2501578748449933 0.257006630911632 1.3241307402406013 0.2675502959031997 1.0 0.028497516818446 0.0568757538574934 0.0002725491832247 0.0020735614034028
interpro_family/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3367,
4
+ "annotations_size": 2583,
5
+ "title": "Average number of proteins per term",
6
+ "value": 1.2717770034843205
7
+ }
interpro_family/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C009/C009_val_log2fc"}