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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Protein localization 0.5888470651623026 3.34482199720024 0.0008233539426896 0.6835845581196545 0.5751127289687 69 Q9NR77,O43933,O15228,O14925,Q13505,Q9NS69,Q9UJ83,P56589,Q2T9J0,O15254,Q10713,P09601,P08574,P12236,Q13011,Q99595,P46379,Q5JRX3,O96008,P21796,P28288,Q9Y5L4,P51648,P05067,O75431,P34913,P50402,O60830,Q13190,Q9Y512,P60059 31
Glycosaminoglycan metabolism 0.8605574874178279 2.757794201390491 0.0058192821539795 0.9997122111116294 0.77190642043054 12 P54802,P16278,O43252,P15586,P07686,P06865,Q8TB61,O43505 8
Sphingolipid metabolism 0.8035805370662029 2.752271626595673 0.0059183409251639 0.9997496086407686 0.77190642043054 25 O95470,P07602,P06280,P16278,O15269,Q96G23,P10619,Q06136,P17900,Q9NZJ7,P07686,P06865,Q13510,P04062 14
Sphingolipid de novo biosynthesis 0.8353997536809548 2.6298592898811064 0.0085420215787399 0.9999937595801944 0.77190642043054 10 O95470,Q06136,O15269,Q96G23 4
Glycosphingolipid metabolism 0.8197945520573494 2.603686099708991 0.0092227182318171 0.9999976092862626 0.77190642043054 15 P07602,P06280,P16278,P10619,P17900,Q9NZJ7,P07686,P06865,Q13510 9
Keratan sulfate keratin metabolism 0.9643069601427728 2.5917471953129056 0.0095489912528152 0.99999849096571 0.77190642043054 5 P16278,P06865,P15586,P07686 4
Gpcr ligand binding 0.795259079784748 2.4475481463949285 0.014383190708521 0.999999998377376 0.77190642043054 10 P07602,P05067,P42892 3
Keratan sulfate degradation 0.965506987808503 2.4175943295939177 0.0156234839148514 0.9999999997205794 0.77190642043054 4 P16278,P15586,P06865 3
Class a 1 rhodopsin like receptors 0.8130083336009409 2.3966746747260013 0.0165446056739773 0.999999999924444 0.77190642043054 8 P07602,P05067,P42892 3
Peptide ligand binding receptors 0.8130083336009409 2.3966746747260013 0.0165446056739773 0.999999999924444 0.77190642043054 8 P07602,P05067,P42892 3
Mitophagy 0.7326084573502104 2.1543987165570857 0.0312089171470857 1.0 0.77190642043054 9 Q9NS69,O96008 2
Phospholipid metabolism 0.4514611486138951 2.1406510543508337 0.0323021883565624 1.0 0.77190642043054 52 Q92604,Q8NCC3,Q10713,Q9BZF1,P42356,Q96N66,P35790,O95674,Q8IV08,Q8IY17,Q9NQZ5,Q9UG56 12
Heparan sulfate heparin hs gag metabolism 0.8908833345529782 2.129844780194994 0.0331844302871222 1.0 0.77190642043054 4 P54802,P16278 2
Pink1 prkn mediated mitophagy 0.7969298266306137 2.0888693557463203 0.0367194850364152 1.0 0.77190642043054 6 Q9NS69,O96008 2
Plasma lipoprotein clearance 0.7119772887161744 2.064732674380525 0.0389483011856519 1.0 0.77190642043054 13 O15118,Q8WTV0 2
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7096626454012283 2.0490866183780425 0.0404536457635611 1.0 0.77190642043054 12 P09601,P51648,P05067,P60059,P46379,P50402 6
O linked glycosylation of mucins 0.8605411834671326 2.010401243228968 0.0443887390165693 1.0 0.77190642043054 4 Q86SF2,O43505,Q10471 3
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.694687168603334 2.009960386950095 0.0444353816097948 1.0 0.77190642043054 17 P19022,Q07065,P05067,Q08431,O43852,Q9BTY2,O76024,Q02818 8
Binding and uptake of ligands by scavenger receptors 0.7180210050111264 1.966159530328606 0.0492801856214493 1.0 0.77190642043054 8 Q8WTV0 1
Hyaluronan metabolism 0.8472257664231543 1.957560009447665 0.0502816637503071 1.0 0.77190642043054 4 P06865 1
Hyaluronan uptake and degradation 0.8472257664231543 1.957560009447665 0.0502816637503071 1.0 0.77190642043054 4 P06865 1
Post translational modification synthesis of gpi anchored proteins 0.7630582134132893 1.9428322229704889 0.0520364332034326 1.0 0.779543233528906 6 Q9ULX3,Q9H490,Q96S52 3
Plasma lipoprotein assembly remodeling and clearance 0.6813693877926394 1.9236098781836155 0.0544035019354993 1.0 0.779543233528906 15 O15118,P61916,Q8WTV0 3
Mitochondrial protein import 0.6252695883236893 1.9114587626776491 0.0559456513354972 1.0 0.779543233528906 30 Q10713,O60830,O96008,P21796,P08574,P12236,O14925,Q9Y512,Q9Y5L4,Q13505,Q99595,O75431,Q5JRX3,Q9NS69 14
Mucopolysaccharidoses 0.975029726516052 1.8853800188726793 0.0593785497096019 1.0 0.779543233528906 3 P54802,P16278 2
Class i peroxisomal membrane protein import 0.7239395764740831 1.8797105752307697 0.0601475335269254 1.0 0.779543233528906 7 P51648,Q9NR77,P28288 3
Lysosome vesicle biogenesis 0.6695520572626174 1.8575996511542303 0.0632258881119653 1.0 0.7847525244712771 14 P05067,P20645 2
Diseases of carbohydrate metabolism 0.6696693987951665 1.853146198191512 0.0638614067013976 1.0 0.7847525244712771 9 P54802,P16278,P15586 3
Diseases associated with glycosaminoglycan metabolism 0.9623527383126856 1.8398396516639008 0.0657917821119067 1.0 0.7847525244712771 3 P06865 1
Chondroitin sulfate dermatan sulfate metabolism 0.9623527383126856 1.8398396516639008 0.0657917821119067 1.0 0.7847525244712771 3 P06865 1
Rhoa gtpase cycle 0.4522865617242829 1.8052188747203577 0.0710404384865577 1.0 0.7847525244712771 49 Q86VI3,P28288,P41440,Q14739,Q13190,Q86UP2,O75116,P27105,P30519,P02786,O75955,O75962,Q9Y4F1,Q15904,Q14254 15
Insulin receptor recycling 0.6586477461720304 1.7994390519371046 0.0719492568297954 1.0 0.7847525244712771 9 Q93050,Q9Y487,Q15904 3
O linked glycosylation 0.7682926829268433 1.7981848719535445 0.0721477160809347 1.0 0.7847525244712771 5 Q10472,Q86SF2,O43505,Q10471 4
Heme degradation 0.8071351870809613 1.796997815722704 0.0723359665247689 1.0 0.7847525244712771 4 P09601 1
Metabolism of fat soluble vitamins 0.7672427580053951 1.7937659517737063 0.072850533583531 1.0 0.7847525244712771 5 Q8N0U8,Q6NUM9 2
Regulation of mecp2 expression and activity 0.654718990047814 1.7776534880093502 0.0754607831614384 1.0 0.7847525244712771 10 Q13555,Q13547,Q96ST3,Q14739,P42858 5
Endosomal vacuolar pathway 0.7996605881504342 1.7668342452523311 0.0772559917364468 1.0 0.7847525244712771 4 P01889,Q9UIQ6 2
Transferrin endocytosis and recycling 0.6476232569385632 1.741158464484012 0.0816558056230376 1.0 0.7847525244712771 11 Q93050,Q9Y487,Q15904,Q9UI12 4
Resolution of d loop structures through synthesis dependent strand annealing sdsa 0.646092722462545 1.7379366632020514 0.0822219745813863 1.0 0.7847525244712771 9 P38398,P54132,Q9UQ84,Q14191,Q99728 5
Resolution of d loop structures 0.646092722462545 1.7379366632020514 0.0822219745813863 1.0 0.7847525244712771 9 P38398,P54132,Q9UQ84,Q14191,Q99728 5
Mitotic telophase cytokinesis 0.6464886577249833 1.735494644206174 0.0826532293176303 1.0 0.7847525244712771 11 Q29RF7,O95235,O60216,Q6KC79,Q9NTI5,Q7Z5K2,Q02241,Q9UQE7,Q8N3U4 9
Attachment of gpi anchor to upar 0.7907944466227551 1.7309693910802846 0.083457223905651 1.0 0.7847525244712771 4 Q9H490,Q96S52 2
Transport of inorganic cations anions and amino acids oligopeptides 0.6574200035532327 1.6812584416262697 0.0927127263219389 1.0 0.7847525244712771 8 Q70HW3,Q9UBX3 2
Egr2 and sox10 mediated initiation of schwann cell myelination 0.6796182153336876 1.6776817173649614 0.0934092504214967 1.0 0.7847525244712771 7 P46939,Q9NR77,Q16850,Q14118 4
Metabolism of steroids 0.448593219999322 1.6734783711851684 0.0942331609418338 1.0 0.7847525244712771 48 Q15800,Q14739,Q9BWD1,Q14849,Q9H4L5,Q99538,Q15392,Q16850,Q9UBM7 9
Vitamin d calciferol metabolism 0.7730268324961849 1.6588338859759892 0.0971492700305249 1.0 0.7847525244712771 4 Q99538 1
Synthesis of pips at the golgi membrane 0.6747143538749494 1.6551250653014271 0.0978991314264834 1.0 0.7847525244712771 7 O00443,Q10713,P42356,Q99570 4
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.7341183296322118 1.653597009533623 0.0982094207182575 1.0 0.7847525244712771 5 Q5KU26,P01889 2
Synaptic adhesion like molecules 0.696198619812479 1.6487771664164468 0.0991932944593376 1.0 0.7847525244712771 6 O75955,P41440 2
Cohesin loading onto chromatin 0.6481095564156163 1.6368661687222816 0.1016584362400512 1.0 0.7959840938004582 8 Q29RF7,O60216,Q6KC79,Q9NTI5,Q7Z5K2,Q9UQE7,Q8N3U4 7
Synthesis of pc 0.7222797840628487 1.603176410711116 0.1088957119275084 1.0 0.799222974446794 5 P35790 1
Iron uptake and transport 0.6156928725861363 1.6031436857088297 0.1089029350472663 1.0 0.799222974446794 18 P09601,Q9UI12,P30519,Q9Y487,Q93050,Q15904 6
Sialic acid metabolism 0.6815911176856688 1.583647353445886 0.1132739915277643 1.0 0.799222974446794 6 P16278 1
Synthesis of very long chain fatty acyl coas 0.6556634542034558 1.5671564503736273 0.1170781270196292 1.0 0.799222974446794 7 Q53GQ0,P33121,Q9NZ01,Q4G176 4
Sema4d in semaphorin signaling 0.6084677081410513 1.5517305015396583 0.1207267212363287 1.0 0.8049817091769443 9 Q9NWH9,P35580,Q7Z406,O75116,Q13464,P35579 6
Assembly of the orc complex at the origin of replication 0.652046246082552 1.5503970654427242 0.1210462424737595 1.0 0.8049817091769443 7 O60684,Q9UBD5,O43913 3
Establishment of sister chromatid cohesion 0.647916666666668 1.5312433449383993 0.1257092618741262 1.0 0.8049817091769443 7 Q29RF7,O60216,Q9NTI5,Q7Z5K2,Q9UQE7,Q8N3U4 6
Sulfur amino acid metabolism 0.6245830962819842 1.5240646716900268 0.127492556752055 1.0 0.8049817091769443 8 Q13126 1
Dcc mediated attractive signaling 0.6962812641872238 1.491953645545301 0.1357112977614778 1.0 0.8049817091769443 5 Q14185,O00401 2
Metabolism of porphyrins 0.639298576021459 1.4912051004210638 0.1359076550010822 1.0 0.8049817091769443 7 P09601 1
Metabolism of folate and pterines 0.592653856722962 1.4727261350505545 0.1408248964830347 1.0 0.8049817091769443 9 Q9H2D1,P41440 2
Cholesterol biosynthesis 0.5910452759140905 1.469748393390409 0.1416299107448635 1.0 0.8049817091769443 18 Q14739,Q9BWD1,Q15392,Q16850,Q9UBM7 5
Epha mediated growth cone collapse 0.6561040746019149 1.4694192534354356 0.1417191082795301 1.0 0.8049817091769443 6 Q13464,P35580,Q7Z406,O75116 4
Sema4d induced cell migration and growth cone collapse 0.6561040746019149 1.4694192534354356 0.1417191082795301 1.0 0.8049817091769443 6 Q13464,P35580,Q7Z406,O75116 4
Ion channel transport 0.577176019736123 1.4658728128697034 0.1426829398257156 1.0 0.8049817091769443 24 P27105,Q9Y487,Q9HD20,Q9C0H2,Q15904,P16615,Q93050 7
Trans golgi network vesicle budding 0.5286501984134534 1.4346239977660404 0.151394272382316 1.0 0.8049817091769443 34 P20645,O75976,P05067,Q12846,P15586,P11717 6
Apoptotic cleavage of cell adhesion proteins 0.6446294421794718 1.4177942583320613 0.1562508409778296 1.0 0.8127446056182577 6 Q07157,P35222,Q16625 3
Amyloid fiber formation 0.6022518502249291 1.41628747044422 0.156691354778522 1.0 0.8127446056182577 8 P05067,Q92542 2
Ros and rns production in phagocytes 0.596468966221882 1.3882878485588863 0.1650494109094435 1.0 0.8176383937606124 8 Q93050,Q9Y487 2
Striated muscle contraction 0.6708986768192129 1.3828713415144096 0.1667043190707979 1.0 0.8203433435383348 5 Q9NYL9,P08670,P28289 3
Transport of vitamins nucleosides and related molecules 0.6158433790025694 1.381852791652353 0.1670169056349173 1.0 0.8203433435383348 7 Q8TB61,Q99808 2
Slc mediated transmembrane transport 0.5721694433792514 1.374190700089471 0.169382487152937 1.0 0.8203433435383348 19 Q70HW3,Q9UBX3,P30825,Q15043,Q8TB61,Q99808 6
Nephrin family interactions 0.5679212506912431 1.348488351681793 0.1775013641606002 1.0 0.8377344788255356 9 Q13813,Q01082,P46940,O43639,P12814,O43707,O00401 7
Glycerophospholipid biosynthesis 0.5234400619876574 1.2986790454887291 0.194054098223519 1.0 0.8793036985092094 31 Q92604,Q8NCC3,Q9BZF1,Q96N66,P35790,O95674,Q8IV08,Q9NQZ5 8
Stat3 nuclear events downstream of alk signaling 0.6845078798691591 1.2958396124393938 0.1950307475650861 1.0 0.8793036985092094 4 P40763,Q13547,Q96ST3 3
Diseases of dna repair 0.5600989270246878 1.290510182237555 0.1968735788189608 1.0 0.8793036985092094 14 P40692,P54132,Q9UQ84,Q14191,Q99728,P38398 6
Cdc6 association with the orc origin complex 0.8115338882282949 1.2902361684785324 0.1969686718326562 1.0 0.8793036985092094 3 Q9UBD5,O43913 2
Wax and plasmalogen biosynthesis 0.6825812847028493 1.2879097407652869 0.1977773843151 1.0 0.8793036985092094 4 O15228,Q6IAN0 2
G alpha 12 13 signalling events 0.5747962345406237 1.2831227161532996 0.1994490864259539 1.0 0.8793036985092094 8 O75962,O75116 2
Signaling by retinoic acid 0.5542811275391305 1.2797161609550023 0.2006449787769622 1.0 0.8793036985092094 9 Q8NBN7,Q15120 2
Epigenetic regulation of gene expression 0.4142139313925236 1.2734884736678922 0.2028447601259362 1.0 0.8793036985092094 47 Q13185,O60264,Q96ST3,Q86YP4,Q12965,Q8WXI9,Q96T88,Q92769,O00159,Q13330,P17480,Q9BQG0,P18074,Q9NY93,Q14839,Q13547,O75530,O94776,O43159,O95602,O75533,P32780,Q9NR30,Q9UIG0,Q9H9Y6,Q9Y483,Q9UHR5,P19388,P19447,P26358 30
Ldl clearance 0.5503877772058408 1.2478707512481069 0.2120783934331966 1.0 0.8793036985092094 11 O15118,P61916,P35610,O94973 4
Inflammasomes 0.6382538473196658 1.2422598245130323 0.2141407132685184 1.0 0.8793036985092094 5 P09601 1
Purinergic signaling in leishmaniasis infection 0.6382538473196658 1.2422598245130323 0.2141407132685184 1.0 0.8793036985092094 5 P09601 1
The nlrp3 inflammasome 0.6382538473196658 1.2422598245130323 0.2141407132685184 1.0 0.8793036985092094 5 P09601 1
Signaling by alk 0.6371158718967305 1.23735873064686 0.2159539329249289 1.0 0.8793036985092094 5 P40763,Q13547,Q96ST3 3
Stimuli sensing channels 0.5609722013575471 1.2159340562328638 0.2240100434864844 1.0 0.8931991284032207 8 Q9C0H2 1
Hs gag degradation 0.9800891530460624 1.188310615431807 0.2347110570130488 1.0 0.91145607068828 2 P54802 1
Ire1alpha activates chaperones 0.5313205661978236 1.184198836099909 0.2363343627675949 1.0 0.91145607068828 23 P49748,Q9UBS4,Q969H8,P43307,O14773,Q9HCU5,O76024 7
Trafficking and processing of endosomal tlr 0.7825037929668509 1.184142586666844 0.2363566246180766 1.0 0.91145607068828 3 Q99538 1
Diseases of glycosylation 0.5362050649514587 1.1704261171772488 0.24182953049297 1.0 0.91145607068828 18 P16278,Q2TAA5,P10619,P06865,P07686,O43505 6
Cs ds degradation 0.9649331352154532 1.135658934334986 0.2560993335091011 1.0 0.9134575200749754 2 P06865 1
Response to elevated platelet cytosolic ca2 0.5032438207407532 1.1182808022575643 0.2634470834957934 1.0 0.9200889391090584 29 P07602,Q8NBX0,Q08380,Q9NZJ7,P05067,Q12846,P13473 7
Peroxisomal protein import 0.5194791030679076 1.1050325727548642 0.2691454753103424 1.0 0.9343637920612716 22 O15254,P34913,Q2T9J0,O43933 4
Transcriptional regulation by mecp2 0.5234517477949225 1.096446102465719 0.2728835978664183 1.0 0.9343637920612716 16 Q13555,Q13547,Q9NWH9,Q96ST3,Q14739,P42858,Q8WYQ5 7
Nr1h2 and nr1h3 mediated signaling 0.6017819944298786 1.0855421331214865 0.2776816133445334 1.0 0.9343637920612716 5 O00767,Q9HCE1,Q9Y4C1 3
Rnd3 gtpase cycle 0.517519079570972 1.0683533385516182 0.2853611567642118 1.0 0.9343637920612716 18 Q9NYL9,Q9Y2I1,Q07065,Q14254,Q86UP2,O75976,Q13464,Q03001 8
Transport of bile salts and organic acids metal ions and amine compounds 0.7476218787158091 1.0575325029590572 0.2902686288130331 1.0 0.9452337399809028 3 Q15043,P35613 2
Nef mediated cd4 down regulation 0.5630012392871598 1.0498234340037478 0.2937992990152536 1.0 0.9522914633974692 6 O94973,O95782,Q96CW1,Q9UI12 4
Nef mediated cd8 down regulation 0.5630012392871598 1.0498234340037478 0.2937992990152536 1.0 0.9522914633974692 6 O94973,O95782,Q96CW1,Q9UI12 4
Rnd1 gtpase cycle 0.5119214193094168 1.0353949639488478 0.3004844966445978 1.0 0.9611333927082788 15 O75976,P51648,Q9ULH0,P02786,Q03001 5
Adherens junctions interactions 0.5523577980066765 1.0021952830419336 0.3162492855272965 1.0 0.9796014454138208 6 P19022,P55196 2
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.574327323375836 0.9685936986669924 0.3327479485796591 1.0 0.9839647154828554 5 Q99808 1
Synthesis of pips at the early endosome membrane 0.5737839053353817 0.9662932056386404 0.3338974849177325 1.0 0.9839647154828554 5 O00443,Q99570 2
Rac1 gtpase cycle 0.3714222184232718 0.9577235649911156 0.338202170728606 1.0 0.9839647154828554 48 Q9Y2I1,Q96F07,Q86VI3,Q7L576,O00401,Q14739,Q9UQB8,Q86UP2,Q96HP0,Q14185,P02786,O75962,Q9Y4F1,P50402 14
Interaction between l1 and ankyrins 0.6016858317048353 0.9573802303882756 0.3383753732092938 1.0 0.9839647154828554 4 Q01082,Q13813 2
Platelet activation signaling and aggregation 0.3707822446470239 0.95180970947111 0.3411934969569357 1.0 0.9839647154828554 48 P07602,Q8NBX0,Q08380,Q9NZJ7,P05067,Q12846,P13473 7
Runx1 regulates expression of components of tight junctions 0.7146254458977327 0.9393367405161904 0.3475578807666304 1.0 0.9847006146333118 3 Q07157,Q16625 2
Eph ephrin mediated repulsion of cells 0.4845374587331552 0.919364813709498 0.3579047871636831 1.0 0.9955423389358118 10 P53680,Q96CW1,P09497,Q92542,O94973,O95782 6
N glycan antennae elongation in the medial trans golgi 0.9004457652303122 0.9155985163867332 0.3598775097799462 1.0 0.9955423389358118 2 P04066 1
Reactions specific to the complex n glycan synthesis pathway 0.9004457652303122 0.9155985163867332 0.3598775097799462 1.0 0.9955423389358118 2 P04066 1
Diseases associated with glycosylation precursor biosynthesis 0.4983992064555159 0.9132815080743412 0.3610945053521872 1.0 0.996934829994082 8 P16278 1
Transport and synthesis of paps 0.8989598811292723 0.9106287505109298 0.3624910166661146 1.0 0.9988164699853296 2 Q8TB61 1
Interactions of vpr with host cellular proteins 0.4512429428956946 0.9086700545051876 0.3635243156187953 1.0 0.9990162101738292 34 P49790,P57740,Q99567,Q9BTX1,O75694,P05141,P55735,P49792,P12236,Q92621,P35658,Q8WUM0,Q8NFH5,Q12769,Q8N1F7,P52294,P52948,P12270 18
Mecp2 regulates transcription of neuronal ligands 0.704563843166288 0.9037290647146936 0.3661390834710096 1.0 0.9990162101738292 3 Q96ST3 1
Loss of function of mecp2 in rett syndrome 0.704563843166288 0.9037290647146936 0.3661390834710096 1.0 0.9990162101738292 3 Q96ST3 1
Prc2 methylates histones and dna 0.5290563361623501 0.8987472061160442 0.3687873264645713 1.0 1.0 6 P26358,Q9Y483 2
Regulation of glucokinase by glucokinase regulatory protein 0.4731716345849603 0.8959282702318464 0.3702910742902821 1.0 1.0 27 P49790,P57740,Q99567,Q9BTX1,O75694,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P52948,P12270 13
E2f enabled inhibition of pre replication complex formation 0.5837863038537174 0.885710537455988 0.3757735285726915 1.0 1.0 4 Q9UBD5 1
Slc transporter disorders 0.4499157774343209 0.8722747322819101 0.3830585186850659 1.0 1.0 33 P49790,P57740,Q99567,Q9BTX1,O75694,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P53985,P52948,P35613,P12270 15
Dna methylation 0.5792513699427148 0.8676968262232946 0.3855603237770961 1.0 1.0 4 Q96T88 1
Transport of mature mrnas derived from intronless transcripts 0.4310711494251708 0.8654888646899824 0.3867705250943078 1.0 1.0 37 P49790,P57740,Q9UBU9,Q99567,Q9C0J8,Q9BTX1,Q9P2I0,O75694,Q09161,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,Q92797,P52948,P12270 18
Glycerophospholipid catabolism 0.8849925705794951 0.8641965190751305 0.3874799441057375 1.0 1.0 2 Q8IY17 1
Sumoylation of ubiquitinylation proteins 0.4646925463843813 0.8604553656740396 0.3895380774784818 1.0 1.0 28 P49790,P57740,Q99567,Q9BTX1,O75694,P55735,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P52948,P12270 14
Sumoylation of chromatin organization proteins 0.4300405340844728 0.8581990137650005 0.3907825805263534 1.0 1.0 37 P49790,P57740,Q99567,Q14781,Q9BTX1,Q13547,O75694,P55735,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P52948,P12270 16
Intra golgi traffic 0.4785064609583844 0.8577192728790307 0.3910474952128142 1.0 1.0 16 Q9UP83,Q13190,O00461,O60476,Q16706 5
Cell cell junction organization 0.5027280102169398 0.8554927898070838 0.3922783943259853 1.0 1.0 7 P19022,P55196 2
Fatty acyl coa biosynthesis 0.4764252132536384 0.8526818124987434 0.3938357794600051 1.0 1.0 14 Q9NZ01,Q9P035,P33121,Q53GQ0,Q4G176,P50897 6
Transcriptional regulation of white adipocyte differentiation 0.4770035778497652 0.8521293518354442 0.3941423025965576 1.0 1.0 15 Q71SY5,O60244,Q15648,O75448,Q9Y2W1 5
Heme signaling 0.5001715863993711 0.843855574175742 0.3987501160204632 1.0 1.0 7 P09601,Q15648 2
Abc transporters in lipid homeostasis 0.8784546805349186 0.8426501682683859 0.3994241244174226 1.0 1.0 2 P28288 1
Diseases of metabolism 0.3874659014888307 0.8425459033315069 0.3994824568388282 1.0 1.0 44 P54802,P16278,P10619,P07686,P15586,P06865,O43505 7
Metabolism of lipids 0.4840273692398821 0.8411983691530117 0.4002368140006451 1.0 1.0 187 Q8NCC3,Q92604,P49748,Q8N9F7,Q96N66,Q96ST3,Q06136,Q9Y305,Q4G176,Q9H4L5,Q15648,Q8IV08,Q15392,P50897,O15254,Q71SY5,P07602,O95470,Q10713,O15269,Q96G23,O43772,Q15165,Q14849,P35790,Q99538,Q8N8N7,Q8IY17,Q9NQZ5,Q9UBM7,Q9BZF1,P06280,P16278,P42356,Q14739,Q9BWD1,Q9NZJ7,P51648,O95674,P06865,P34913,Q13510,P04062,Q9UG56,Q16850,Q15800,P10619,P17900,P07686,P37268 50
Synthesis of pips at the late endosome membrane 0.6864133030164572 0.8401482204789904 0.4008252863066661 1.0 1.0 3 O00443 1
Alpha oxidation of phytanate 0.5711068654764951 0.8355134835116417 0.403428658391745 1.0 1.0 4 P51648 1
Ripk1 mediated regulated necrosis 0.4704635660787265 0.833225039403485 0.4047178233720867 1.0 1.0 12 O75955,O00560,P41440 3
Sumoylation of sumoylation proteins 0.4546666840944189 0.7998263061468587 0.4238114394425465 1.0 1.0 28 P49790,P57740,Q99567,Q9BTX1,O75694,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P52948,P12270 13
Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.4628528971017003 0.794933463781153 0.4266522071611938 1.0 1.0 12 Q14839,Q13185,Q13547,Q92769,O94776,Q8WXI9,Q13330 7
Signaling by insulin receptor 0.4653188812305033 0.7916882417660012 0.4285424800335726 1.0 1.0 15 Q93050,Q9Y487,Q15904 3
Cristae formation 0.4630225568906185 0.7755057980122182 0.4380408407422229 1.0 1.0 19 P56134,Q9BUR5,Q9Y512,Q16891,Q13505,O75431,O75964 7
Ns1 mediated effects on host pathways 0.4367340227998618 0.7628811882460517 0.4455342561234232 1.0 1.0 32 P49790,P57740,Q99567,Q9BTX1,O75694,P55735,P49792,O00629,Q92621,P35658,Q8WUM0,Q8NFH5,Q12769,Q8N1F7,P52294,P52948,P12270 17
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.5522764100929585 0.7620538697099649 0.4460278534520263 1.0 1.0 4 Q14185 1
Wnt5a dependent internalization of fzd4 0.4604252449501254 0.7341686014526958 0.4628459873051511 1.0 1.0 8 P53680,Q96CW1,P09497,O94973,O95782 5
Wnt5a dependent internalization of fzd2 fzd5 and ror2 0.4604252449501254 0.7341686014526958 0.4628459873051511 1.0 1.0 8 P53680,Q96CW1,P09497,O94973,O95782 5
Retrograde transport at the trans golgi network 0.4549961189362901 0.7333613563368199 0.4633380619745226 1.0 1.0 17 P20645,P11717 2
Synthesis of pg 0.5422867386914039 0.7237080622076035 0.4692449824871021 1.0 1.0 4 O95674,Q8IV08 2
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.6510107015457716 0.7191777306574115 0.4720314187036158 1.0 1.0 3 Q9HCE1,Q9Y4C1 2
Phase i functionalization of compounds 0.4491579965938134 0.7139356474378034 0.4752669732247307 1.0 1.0 14 P30837,P07099,Q16850 3
Transcription of e2f targets under negative control by dream complex 0.5109122836645154 0.7065015853083997 0.4798762671970362 1.0 1.0 5 P28749,Q99741,Q13547 3
Mecp2 regulates neuronal receptors and channels 0.4681144767371572 0.7003189003782881 0.4837281708817222 1.0 1.0 7 Q92769,Q9NWH9,Q13547,Q96ST3 4
Signaling by flt3 fusion proteins 0.5358173728416927 0.6991390117122915 0.4844651604029502 1.0 1.0 4 Q14789,Q9UBW7 2
Sumoylation of dna methylation proteins 0.5355120366399573 0.6979848659032867 0.4851866586999178 1.0 1.0 4 Q14781 1
Myogenesis 0.4816269949907634 0.6939802665442758 0.4876945843491636 1.0 1.0 6 P19022 1
Cargo concentration in the er 0.443563901300995 0.6920281572402365 0.4889196465615451 1.0 1.0 13 P49257,P53634,Q13190,Q96PC5,Q9HCU5,Q5JRA6,O95487 7
Transport of small molecules 0.414296106498668 0.6889531645748002 0.4908527414367116 1.0 1.0 138 Q8WTV0,P08183,Q70HW3,Q9UBX3,P49721,Q8TB61,Q99808,Q10713,P09601,Q15043,O15118,P30519,Q9H0U3,Q9Y487,Q9HD20,Q9C0H2,Q93050,P28288,P30825,Q9BU23,P16615,P61916,Q9UI12,P27105,P45880,P02786,P60900,Q15904 28
Transport of the slbp dependant mature mrna 0.4277513232483245 0.6864151213745777 0.4924513716664198 1.0 1.0 31 P49790,P57740,Q9UBU9,Q99567,Q9BTX1,Q09161,O75694,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P52948,P12270 15
Rora activates gene expression 0.6407484614134058 0.6850354406284351 0.49332155718864 1.0 1.0 3 Q15648 1
Respiratory electron transport 0.3414076271122583 0.6842948849004312 0.4937889763097574 1.0 1.0 48 P13073,Q86Y39,P08574,P47985,Q9UDW1,O00483,Q96I36,O75880,Q9NPL8,O43676,Q9P0J0 11
Positive epigenetic regulation of rrna expression 0.4285691680182103 0.6739884764589956 0.5003186399506374 1.0 1.0 30 Q13185,O60264,Q12965,Q86YP4,Q8WXI9,Q92769,O00159,Q13330,Q9BQG0,Q9NY93,Q14839,Q13547,O94776,O95602,O75533,Q9NR30,Q9UIG0,Q9H9Y6,P19388 19
Insulin processing 0.4323484422309875 0.6730345194923891 0.5009253301736174 1.0 1.0 9 Q8TAG9,Q9UPT5 2
Rrna modification in the nucleus and cytosol 0.3058206595064494 0.6578518791892345 0.5106333143688255 1.0 1.0 57 Q9Y3A4,Q9NV06,Q9BVJ6,Q9NQZ2,Q969X6,P55769,Q14690,Q9Y2R4,O15213,O75691,Q9H583,Q9H6R4,Q9H0A0,Q14692,Q8IY37 15
Rnd2 gtpase cycle 0.4401493822004141 0.6553708403960945 0.5122290208981113 1.0 1.0 18 Q9Y2I1,Q07065,Q9BTT6,Q9ULH0,P02786,Q03001 6
Rho gtpases activate cit 0.4299161477771029 0.6509114156276261 0.5151036719329989 1.0 1.0 10 O43663,P35580,Q7Z406,O14974 4
Export of viral ribonucleoproteins from nucleus 0.4255691247026258 0.6408132086132428 0.5216440501325881 1.0 1.0 29 P49790,P57740,Q99567,Q9BTX1,O75694,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P52948,P12270 13
Metabolism of steroid hormones 0.4673748780534452 0.6347339720060481 0.5256019331376927 1.0 1.0 6 Q8NBQ5,Q14849 2
Mitochondrial calcium ion transport 0.4342852191717645 0.6305048778144239 0.5283643124085262 1.0 1.0 16 Q10713,P21796,Q92667,P45880,Q9BPX6 5
Sumoylation of rna binding proteins 0.408046415095628 0.6243004702202329 0.5324302751790118 1.0 1.0 34 P49790,P57740,Q99567,Q14781,Q9BTX1,O75694,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,Q9Y2X3,P52948,P12270 15
Interleukin 35 signalling 0.6181564719916994 0.6116577079418931 0.5407642486774809 1.0 1.0 3 P40763 1
Interleukin 27 signaling 0.6181564719916994 0.6116577079418931 0.5407642486774809 1.0 1.0 3 P40763 1
Sema4d mediated inhibition of cell attachment and migration 0.6159656556627284 0.6046856737964662 0.5453878688874356 1.0 1.0 3 Q9NWH9 1
Fatty acid metabolism 0.2946464247588944 0.6015297072274274 0.5474872314357491 1.0 1.0 53 P49748,O43772,Q15165,Q9Y305,Q4G176,P51648,Q8N8N7,P34913,P50897,O15254 10
Cardiac conduction 0.4153315265144761 0.593069326017243 0.5531347576189458 1.0 1.0 9 Q99996,P54709,Q13555,P16615 4
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.2994321724704683 0.592271485976756 0.553668806649315 1.0 1.0 57 P13073,Q86Y39,P08574,P47985,Q9UDW1,O00483,Q96I36,O75880,Q9NPL8,O75964,O43676,Q9P0J0 12
Rhoc gtpase cycle 0.3948161498748621 0.562632526677458 0.5736851384140533 1.0 1.0 35 P41440,P28288,Q86VI3,Q14739,P27105,P02786,O75955,Q14254 8
Gap junction degradation 0.4495261954595513 0.5625849179641402 0.573717564400672 1.0 1.0 6 Q96CW1,Q9UM54 2
Cargo recognition for clathrin mediated endocytosis 0.4112737628989346 0.557491750542344 0.5771914938446474 1.0 1.0 29 Q14108,P02786,P20645,P11717 4
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.4723378941106576 0.5570350565783586 0.5775034775295327 1.0 1.0 5 Q9C037,Q7Z434,Q14258,O15111 4
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters 0.4112856560189333 0.5535546773104176 0.5798836510113217 1.0 1.0 11 P04439,O94973,Q96CW1,Q9UI12 4
Sumoylation of dna replication proteins 0.3853901982020442 0.5511733717460774 0.5815148321365236 1.0 1.0 37 P49790,P57740,Q99567,Q9BTX1,O75694,P55735,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P52948,Q02880,P11388,P12270 16
Ion transport by p type atpases 0.4182916654310496 0.5448887140530783 0.5858300588345853 1.0 1.0 8 P54709,Q13555,P16615,Q9HD20 4
Cdc42 gtpase cycle 0.3880019105817008 0.5426192004362664 0.5873920163559223 1.0 1.0 36 Q86VI3,Q14739,Q9UQB8,Q86UP2,Q96HP0,P27105,Q658P3,P02786,O75962,Q9Y4F1,O00401 11
Antigen presentation folding assembly and peptide loading of class i mhc 0.4147281440547544 0.5395831675512495 0.5894845274417411 1.0 1.0 15 P04439,P55735,P01889,Q9NZ08,O95487 5
Vldlr internalisation and degradation 0.4289422645533671 0.5335395591483303 0.5936601345653763 1.0 1.0 7 P53680,O95782,Q96CW1,O94973 4
Transport of mature transcript to cytoplasm 0.3040709317000463 0.5265270099503204 0.598522090532003 1.0 1.0 65 P49790,P35658,Q8WUM0,O60508,Q01081,P12270,Q13769,P57740,Q9UBU9,Q9C0J8,Q9BTX1,Q9Y3Y2,O75694,Q8NI27,Q9P2I0,P49792,Q92621,P52948,Q96FV9,Q99567,Q09161,Q15287,Q12769,Q8N1F7,Q92797,O00148 26
Gene silencing by rna 0.3296576689080217 0.5246223157928197 0.5998457703821747 1.0 1.0 47 P49790,P57740,Q99567,Q9BTX1,O75694,P49792,Q92621,P35658,Q8WUM0,Q8N2A8,P30876,O15397,Q12769,P52948,Q8N1F7,Q8WYQ5,P19388,P12270 18
Rho gtpases activate rocks 0.4006545657652932 0.5150328158016788 0.6065300888174345 1.0 1.0 10 O14974,P35580,Q7Z406,O75116,Q13464 5
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.5849246906119763 0.5090470522423833 0.610719243673381 1.0 1.0 3 P18887 1
Diseases associated with o glycosylation of proteins 0.7676077265973261 0.503453385626614 0.61464554573606 1.0 1.0 2 O43505 1
B wich complex positively regulates rrna expression 0.4100028584771494 0.5014602905714046 0.6160472177520862 1.0 1.0 20 O00159,Q9NR30,Q9UIG0,Q9H9Y6,O95602,O75533,Q9BQG0,P19388,Q9NY93 9
Nrage signals death through jnk 0.4181547619047638 0.4899196226793446 0.624190776935492 1.0 1.0 7 Q14344,Q92974,Q9H8V3,Q9NY61,O75962,P63000 6
Rhob gtpase cycle 0.4021534302973865 0.4862499427385018 0.626789965461803 1.0 1.0 27 P41440,Q86VI3,P27105,P02786,O75955,Q14254 6
Transcriptional regulation by e2f6 0.397019374068549 0.4792714409323925 0.6317455364758202 1.0 1.0 12 Q13185,Q15022,O75530,O14757,Q8IWI9,Q9UBK9,Q96KQ7,Q9H9B1,Q99496,P45973,P38398 11
Sensory processing of sound by outer hair cells of the cochlea 0.3986590809689352 0.4783028478179457 0.6324346697430832 1.0 1.0 13 Q9Y2J2,Q01082,O00159,P35579,Q13813 5
Regulation of tp53 activity through acetylation 0.3945407647631921 0.4774867511393147 0.6330155529599164 1.0 1.0 11 Q14839,Q13547,Q9NPI1,Q92769,O94776,Q8WXI9 6
Transcriptional regulation of pluripotent stem cells 0.5678726112939521 0.4593218993491175 0.6460030238627203 1.0 1.0 3 P40763 1
Complex i biogenesis 0.3972214033323245 0.4529327838897939 0.6505971430934603 1.0 1.0 26 Q86Y39,O43676,Q9NPL8 3
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.3929337101722832 0.4525385725670872 0.6508810399419374 1.0 1.0 13 Q13547,Q96ST3,O15047,Q9HCE1,Q15291 5
Peptide hormone metabolism 0.3959598453485461 0.45198669126635 0.6512785701321393 1.0 1.0 15 P67812,P35222,Q8TAG9,Q9UPT5,O00471 5
Synthesis of pe 0.5649551515887263 0.4510371427216275 0.6519627793653919 1.0 1.0 3 P35790 1
Proton coupled monocarboxylate transport 0.7473997028231806 0.4488282924933983 0.6535555274532079 1.0 1.0 2 P35613 1
Protein protein interactions at synapses 0.3926235635161366 0.4435647984200981 0.6573572608620624 1.0 1.0 14 O75955,Q9Y2J2,P41440 3
Acyl chain remodelling of pg 0.7429420505200602 0.4371610382928011 0.6619945634474096 1.0 1.0 2 Q92604 1
Transcriptional regulation by small rnas 0.3586464890518951 0.4290426554533077 0.6678921829069822 1.0 1.0 39 P49790,P57740,Q99567,Q9BTX1,O75694,P49792,Q92621,P35658,Q8WUM0,P30876,Q12769,O15397,Q8N1F7,P52948,P19388,P12270 16
Hdacs deacetylate histones 0.3854599480893613 0.4281332425037318 0.6685541157367636 1.0 1.0 12 Q14839,Q13547,Q86YP4,Q92769,O94776,Q8WXI9,Q13330 7
Nuclear pore complex npc disassembly 0.3857596390187791 0.4256723715852764 0.6703465968499573 1.0 1.0 30 P49790,P57740,Q99567,Q9BTX1,O75694,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P52948,P12270 13
Interleukin 7 signaling 0.7378900445765237 0.4241132666862092 0.6714832106421538 1.0 1.0 2 P51532 1
Energy dependent regulation of mtor by lkb1 ampk 0.3858391454937193 0.4101903001523749 0.6816663557787468 1.0 1.0 8 Q9Y2Q5,P42345 2
Meiotic synapsis 0.3839838290457496 0.3984254943658441 0.6903165683849304 1.0 1.0 15 Q9BTC0,O60216,Q8WXH0,Q14683,Q9UH99,Q9UQE7,P38398,Q8N3U4 8
Maturation of sars cov 2 spike protein 0.3750065966314896 0.3929685551665065 0.6943427062871192 1.0 1.0 11 Q16706,Q9H0U3 2
Viral messenger rna synthesis 0.3627458391465853 0.3850172188760464 0.7002246582892027 1.0 1.0 36 P49790,P57740,Q99567,Q9BTX1,O75694,P49792,Q92621,P35658,Q8WUM0,P30876,Q12769,Q8N1F7,P52948,P19388,P12270 15
Interferon alpha beta signaling 0.3678155000602228 0.3847053357082418 0.7004557415768304 1.0 1.0 9 P04439,P01889 2
Antimicrobial peptides 0.7194650817236266 0.3781702028030966 0.7053041593780032 1.0 1.0 2 P81605 1
Interleukin 23 signaling 0.7167904903417541 0.371723280894885 0.710098889496414 1.0 1.0 2 P40763 1
Plasma lipoprotein remodeling 0.7167904903417543 0.371723280894885 0.710098889496414 1.0 1.0 2 Q9BU23 1
Vxpx cargo targeting to cilium 0.3632801729543549 0.36631059494529 0.7141333245925179 1.0 1.0 9 Q8TAG9,Q9UPT5 2
Retrograde neurotrophin signalling 0.3630136986301306 0.3652394169339181 0.7149326972129355 1.0 1.0 9 P53680,Q00610,Q96CW1,Q9UQ16,P50570,P09496,O94973,O95782 8
Incretin synthesis secretion and inactivation 0.3946499572112115 0.360126623006694 0.7187524443522826 1.0 1.0 6 P67812 1
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.3946499572112115 0.360126623006694 0.7187524443522826 1.0 1.0 6 P67812 1
Homology directed repair 0.3024231463867304 0.3534565716358062 0.7237461810628947 1.0 1.0 48 Q92547,Q9NXR7,P41440,Q14676,P54132,Q9UNS1,Q9UQ84,Q14191,P35251,Q99728,O96028,Q9NR33 12
Trafficking of glur2 containing ampa receptors 0.3903253722406641 0.3457251482438468 0.7295492828226535 1.0 1.0 6 O95782,Q96CW1,O94973 3
Initiation of nuclear envelope ne reformation 0.3716507782669456 0.3454857943421675 0.7297291880668608 1.0 1.0 15 Q14739 1
Neutrophil degranulation 0.4151586642828292 0.3441366279366442 0.7307435381743237 1.0 1.0 173 P42785,Q9Y2Q5,Q92820,O15260,P10253,Q9BTY2,P11279,P13473,P11717,P07602,Q99536,P01889,P30519,Q9H0U3,O00584,O00560,Q93050,O00462,P06280,P16278,Q9NZJ7,Q92542,P15586,Q13510,O00754,P04066,Q13813,P61916,P31949,Q07065,P10619,Q7L576,P17900,P27105,P07384,P07686 36
Miscellaneous transport and binding events 0.4093535660131732 0.341493014510668 0.7327324627786449 1.0 1.0 5 Q9H0U3 1
Basigin interactions 0.3885577955598416 0.3399147775282087 0.7339207077129923 1.0 1.0 6 P54709,P35613 2
Miro gtpase cycle 0.5218856072580511 0.3372654260645195 0.7359168204130881 1.0 1.0 3 Q8IXI2 1
G alpha i signalling events 0.3753671324201544 0.3368140489317906 0.736257081747181 1.0 1.0 24 P07602,P05067 2
Hdms demethylate histones 0.3658937947851317 0.334069206939413 0.7383273358137288 1.0 1.0 8 P29375,Q9Y2K7 2
Leishmania infection 0.3417856874451233 0.3221593381596364 0.7473319870797763 1.0 1.0 39 Q96F07,P09601,Q7L576,Q9UQB8,P05067 5
Pkmts methylate histone lysines 0.3698838387194787 0.3121556246576533 0.754922254600684 1.0 1.0 21 Q9H7B4 1
Rna polymerase iii transcription initiation from type 1 promoter 0.3609917136693288 0.3091164557717318 0.7572329418946737 1.0 1.0 14 Q9Y5Q9,Q9UKN8,Q9Y5Q8,Q12789,Q9BUI4 5
Regulation of pten localization 0.689153046062408 0.3086092277850548 0.7576188005368918 1.0 1.0 2 Q93009 1
Degradation of the extracellular matrix 0.3477077466882017 0.3056141971358126 0.7598984096163051 1.0 1.0 9 Q92542 1
Processing of intronless pre mrnas 0.3635223866539724 0.3054142305038047 0.7600506848590876 1.0 1.0 16 Q5KU26,Q09161,Q9C0J8,Q9P2I0 4
Postmitotic nuclear pore complex npc reformation 0.3684358048745227 0.304808401795964 0.7605120821441762 1.0 1.0 24 Q92973,P57740,Q9BTX1,O75694,P55735,Q8NFH5,Q92621,Q12769,Q8WUM0,Q8N1F7,P52948,Q8WYP5 12
Translation of sars cov 1 structural proteins 0.3657738095238116 0.2980879746454588 0.7656360194471667 1.0 1.0 7 P27824,P49841,P14314,P49840,Q13724,Q10472 6
P75ntr negatively regulates cell cycle via sc1 0.6841010401188716 0.2977898828820032 0.7658635367317075 1.0 1.0 2 Q13547 1
Traf3 dependent irf activation pathway 0.5050535077288819 0.297608840117702 0.7660017267194905 1.0 1.0 3 Q7Z434,Q14258 2
Recruitment of mitotic centrosome proteins and complexes 0.3565231956828755 0.291324212451311 0.7708033712774573 1.0 1.0 32 O94927,O95684,Q15154,Q99996,P04350,O75935 6
Signaling by vegf 0.3644909124834719 0.2909198102371892 0.7711126499089347 1.0 1.0 26 Q96F07,Q7L576,Q9UQB8,O75116,P42345,Q14185 6
Rhoj gtpase cycle 0.3638139614823497 0.2843319407210258 0.7761560106437704 1.0 1.0 22 Q86VI3,P27105,Q658P3,P02786,O75962,O00401 6
Nuclear receptor transcription pathway 0.4967198822955901 0.2790697729534931 0.7801912796339392 1.0 1.0 3 Q15648 1
Regulated necrosis 0.3581660638190646 0.2779623351991828 0.7810412719424105 1.0 1.0 17 O75955,O00560,P41440 3
Linoleic acid la metabolism 0.674294205052007 0.2774465141358772 0.781437269756865 1.0 1.0 2 P33121 1
Integrin cell surface interactions 0.4044606316786154 0.2733569660382854 0.7845788295264824 1.0 1.0 4 P35613 1
Met activates ras signaling 0.4028644049872777 0.2693729819837219 0.78764267524456 1.0 1.0 4 Q96P70 1
Rac2 gtpase cycle 0.3425306935469352 0.2689656469675997 0.787956118569896 1.0 1.0 36 Q7L576,Q14739,Q13505,Q86XL3,P02786 5
Rna polymerase i promoter escape 0.3525725476855251 0.2619441870911821 0.7933644722576165 1.0 1.0 16 Q13185,Q9H9Y6,O95602,P17480,P18074,P19388,P19447 7
Metalloprotease dubs 0.3541133883909126 0.2608972323046921 0.7941717592527193 1.0 1.0 7 O95630,Q9NXR7,Q99728 3
Fanconi anemia pathway 0.3347778473375004 0.2583988443892105 0.7960991083672104 1.0 1.0 9 O15360 1
Rhov gtpase cycle 0.3530591693184307 0.2578137479570199 0.7965506537480045 1.0 1.0 17 Q93008,Q03001,Q13813,Q01082,Q9NNW5,Q96KM6,O00401 7
Unfolded protein response upr 0.3304497074140468 0.2546979322501961 0.7989564134154474 1.0 1.0 39 P43307,O14773 2
Apoptotic cleavage of cellular proteins 0.354718180051695 0.254589912502962 0.7990398511732593 1.0 1.0 19 P35222,Q16625,Q07157,Q14126,Q13464,Q13813 6
Downregulation of smad2 3 smad4 transcriptional activity 0.351343869141279 0.2524051507091115 0.8007279193184957 1.0 1.0 7 Q93008,P09874,Q13485,Q13547 4
Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.6597325408618139 0.2488803855700248 0.8034533080465422 1.0 1.0 2 P62942 1
Formation of the cornified envelope 0.3759659749712995 0.2473841482930285 0.8046109408384925 1.0 1.0 5 P07384 1
Keratinization 0.3759659749712995 0.2473841482930285 0.8046109408384925 1.0 1.0 5 P07384 1
Aurka activation by tpx2 0.3487780972103541 0.2436575900991005 0.8074960216960658 1.0 1.0 31 O94927,Q96SN8,O95684,Q9UIS9,Q15154,Q99996,P04350,O75935 8
Caspase activation via dependence receptors in the absence of ligand 0.6540861812778614 0.2383414933533659 0.8116162414007213 1.0 1.0 2 Q9UKG1 1
Pre notch expression and processing 0.3339431677875169 0.2255427420479567 0.8215570784582391 1.0 1.0 8 P16615,Q9H488 2
Recruitment of numa to mitotic centrosomes 0.3325749553774769 0.2159599339335027 0.8290189786753523 1.0 1.0 36 O94927,O95684,Q15154,Q99996,Q14980,P04350,O75935 7
Hdr through homologous recombination hrr 0.3460495423950026 0.2144017278675173 0.8302337943506748 1.0 1.0 28 Q92547,P41440,P54132,Q9UQ84,Q14191,P35251,Q99728,P38398,Q9NR33 9
Rna polymerase i transcription initiation 0.3461872003183673 0.2115656848124971 0.8324458828420427 1.0 1.0 22 Q14839,Q13547,Q92769,O94776,Q8WXI9,Q9H9Y6,O95602,Q13330,P17480,P32780,P18074,P19388,P19447 13
Anchoring of the basal body to the plasma membrane 0.3432422174907548 0.2110966982941585 0.8328118165623057 1.0 1.0 30 O94927,O95684,Q15154,Q99996,P04350,O75935 6
Glucagon like peptide 1 glp1 regulates insulin secretion 0.3734760630389621 0.2026136919849249 0.8394369873178569 1.0 1.0 4 P62873,P46940,P10644 3
Rrna processing in the mitochondrion 0.3572278405710867 0.2020532572211896 0.8398750894509006 1.0 1.0 5 Q7L0Y3,O15091,Q9BQ52,Q8WVM0 4
Sensing of dna double strand breaks 0.3713945881653362 0.1983727582968937 0.8427534296307537 1.0 1.0 4 P49959,P52292,Q92878 3
Regulation of plk1 activity at g2 m transition 0.3312021671296902 0.1964679704407603 0.8442438999828716 1.0 1.0 35 O94927,O14974,O95684,Q15154,Q99996,P04350,O75935 7
Rna polymerase i transcription termination 0.3277609923425316 0.1953338547326702 0.8451315952589038 1.0 1.0 13 Q9H9Y6,O95602,P17480,P18074,P19388,P19447 6
Mitochondrial biogenesis 0.3339781156735308 0.1897887436411943 0.8494746768572239 1.0 1.0 33 P56134,O00411,Q00059,Q9BUR5,Q15648,Q16891,Q13505,Q9Y512,O75431,Q96RR1,O75964 11
Maturation of sars cov 1 spike protein 0.3654475170978389 0.1866190761664681 0.8519593088882527 1.0 1.0 4 P27824,Q13724,P14314 3
Signaling by tgf beta receptor complex in cancer 0.621991084695395 0.1842713101221891 0.853800619712257 1.0 1.0 2 P62942 1
Signaling by bmp 0.6219910846953949 0.1842713101221889 0.8538006197122572 1.0 1.0 2 Q7Z3T8 1
Rho gtpases activate ktn1 0.3190926864186119 0.1816003271657409 0.855896392077768 1.0 1.0 8 P84095 1
The role of nef in hiv 1 replication and disease pathogenesis 0.3231214112925121 0.1801355033165013 0.8570461908602447 1.0 1.0 13 P04439,O94973,Q96CW1,Q9UI12 4
Copi dependent golgi to er retrograde traffic 0.2677422986087991 0.178213168892886 0.8585555679918422 1.0 1.0 50 Q9P2W9,O95235,O15260,Q96Q89,P24390 5
Peroxisomal lipid metabolism 0.319632237131333 0.177688826994152 0.8589673603789181 1.0 1.0 12 P51648,O15254 2
Trna processing in the mitochondrion 0.357121617603341 0.1710725350442076 0.8641667313569337 1.0 1.0 4 Q7L0Y3,O15091,Q9BQ52 3
Hdr through single strand annealing ssa 0.3304874551392115 0.1696346277297375 0.8652974882157842 1.0 1.0 18 Q92547,P38398,P54132,Q9UQ84,Q14191,Q99728 6
Regulation of pten gene transcription 0.3338308084548638 0.1648831705723329 0.869035939028074 1.0 1.0 22 Q14839,Q14781,Q13547,Q86YP4,Q9Y2Q5,Q92769,Q8WXI9,O75530,O94776,Q13330,Q6IAA8,P42345 12
Diseases of mismatch repair mmr 0.3378941106484185 0.1613535317541687 0.8718149633193519 1.0 1.0 5 P40692,P20585,P52701,P54278 4
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.4316290130796558 0.1611332605139781 0.87198844441348 1.0 1.0 3 P63000,O14786 2
Translesion synthesis by polk 0.3068604759580983 0.1576545851504379 0.8747289886394518 1.0 1.0 10 P41440 1
Nuclear envelope breakdown 0.3123056571043049 0.1555909287595851 0.876355475659699 1.0 1.0 39 P49790,P57740,Q99567,Q9BTX1,O75694,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P52948,P12270,P50402 14
Trafficking of ampa receptors 0.3053331683175347 0.1532231616935752 0.8782222929486161 1.0 1.0 10 Q13555,Q96CW1,Q9UM54,O94973 4
Free fatty acids regulate insulin secretion 0.5994056463595853 0.1522188383865368 0.8790143362167135 1.0 1.0 2 O95573 1
Dopamine neurotransmitter release cycle 0.5940564635958407 0.1453473504751835 0.8844366313529601 1.0 1.0 2 O14936 1
Regulation of lipid metabolism by pparalpha 0.3282550368471735 0.1450782858611718 0.8846490622647829 1.0 1.0 22 Q71SY5,Q96ST3,P33121,O60244,Q15648,P37268,O75448,Q9Y2W1 8
Netrin 1 signaling 0.3077635526980385 0.1417930955239693 0.8872434379392713 1.0 1.0 12 O75962,Q14185,O00401 3
Sting mediated induction of host immune responses 0.3139653531813448 0.1411853776691391 0.8877234972930401 1.0 1.0 6 P78527 1
Extracellular matrix organization 0.3258820132736472 0.1367434294615135 0.8912336001958527 1.0 1.0 30 P05067,Q92542,P07384,Q03001 4
Rho gtpases activate wasps and waves 0.3202506761394954 0.1359737774983146 0.8918420109312852 1.0 1.0 18 Q9UQB8,Q96F07 2
Processing of dna double strand break ends 0.3212817317064021 0.1329067355096241 0.894267139998876 1.0 1.0 33 Q92547,Q9NXR7,Q14676,P54132,Q9UNS1,Q9UQ84,Q14191,Q99728,O96028 9
Homologous dna pairing and strand exchange 0.3199311665143015 0.1296233135626609 0.8968644573066133 1.0 1.0 19 Q92547,P38398,P54132,Q9UQ84,Q14191,Q99728 6
G0 and early g1 0.3032785655576586 0.1279348383212314 0.8982005405792839 1.0 1.0 7 P28749,Q99741,Q13547 3
Flt3 signaling in disease 0.3048288872344701 0.1237286929408843 0.9015300925344004 1.0 1.0 6 Q14789,Q9UBW7 2
Rhou gtpase cycle 0.3073728867260861 0.1168098934662066 0.9070107035747116 1.0 1.0 15 Q13813,O14964,Q01082,Q9NNW5,Q9UM54,Q03001 6
Vegfr2 mediated cell proliferation 0.5687964338781589 0.1165264316582737 0.9072353393494852 1.0 1.0 2 P19174 1
Ion homeostasis 0.2932260169580879 0.1160361150600033 0.9076239194282778 1.0 1.0 8 P54709,Q13555,P16615 3
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.3947658458497864 0.1159650865339619 0.9076802119754332 1.0 1.0 3 P28749 1
Gap junction trafficking and regulation 0.3004422208262385 0.1129787131530027 0.9100474315895426 1.0 1.0 13 Q96CW1,Q9UM54,Q07157,P04350,P09497 5
Intra golgi and retrograde golgi to er traffic 0.2969838183458697 0.1124179297633857 0.910492039544955 1.0 1.0 96 Q9P2W9,O95235,Q10471,P20645,O15260,O00461,P24390,O60476,Q96Q89,Q16706,P53365,P11717,O75935 13
Interferon gamma signaling 0.3023088928090172 0.1027851782467489 0.9181334689997972 1.0 1.0 15 Q13555,P19474,P01889 3
Nuclear import of rev protein 0.3156788323709258 0.1002918866935032 0.920112598498028 1.0 1.0 31 P49790,P57740,Q99567,Q9BTX1,O75694,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P52948,P12270 13
Rac3 gtpase cycle 0.3130527006776141 0.0989023808651506 0.9212157785197432 1.0 1.0 33 Q7L576,Q14739,Q9UQB8 3
Vasopressin regulates renal water homeostasis via aquaporins 0.3733650416171159 0.0964905777958035 0.9231309568393572 1.0 1.0 3 P62873,P10644 2
Aquaporin mediated transport 0.3733650416171159 0.0964905777958035 0.9231309568393572 1.0 1.0 3 P62873,P10644 2
Glucagon signaling in metabolic regulation 0.3733650416171159 0.0964905777958035 0.9231309568393572 1.0 1.0 3 P62873,P10644 2
Fcgr3a mediated il10 synthesis 0.3733650416171155 0.0964905777958029 0.9231309568393578 1.0 1.0 3 P19174,P10644 2
Neurotransmitter clearance 0.5465081723625571 0.0958522972895604 0.9236378813049884 1.0 1.0 2 P21964 1
Cargo trafficking to the periciliary membrane 0.3104017274716164 0.0956274191907069 0.9238164876255954 1.0 1.0 20 Q10713,A6NIH7,Q8TAG9,Q9UPT5 4
Class b 2 secretin family receptors 0.5426448736998528 0.0926967018916494 0.9261445172402478 1.0 1.0 2 Q9Y3E5 1
Processing of capped intronless pre mrna 0.303920620077706 0.0877607114664323 0.9300668649399412 1.0 1.0 18 Q5KU26,Q09161,Q9C0J8,Q9P2I0 4
Negative epigenetic regulation of rrna expression 0.3126521203094994 0.0845649688416738 0.932607250085654 1.0 1.0 26 Q13547,Q96ST3,O60264,O43159,Q9H9Y6,O95602,Q9UHR5,P17480,P32780,P18074,P19388,P19447,P26358 13
Constitutive signaling by aberrant pi3k in cancer 0.2792255551151413 0.0830724758530598 0.9337939112680552 1.0 1.0 6 Q9NWH9 1
Cilium assembly 0.2473967453259891 0.0804040989444469 0.9359158669756428 1.0 1.0 61 O94927,Q10713,O95684,Q15154,Q8TAG9,Q9UPT5,Q99996,O00471,P04350,A6NIH7,O75935 11
Repression of wnt target genes 0.2762414510853474 0.0731155202845808 0.941714191313464 1.0 1.0 4 Q13363,Q13547,P56545 3
Polymerase switching 0.2806350971626068 0.0722942547405508 0.9423677367874734 1.0 1.0 12 P41440 1
Beta oxidation of butanoyl coa to acetyl coa 0.3347205707491012 0.0721817765941569 0.942457247510627 1.0 1.0 3 P40939,P30084 2
Non integrin membrane ecm interactions 0.2662897947039606 0.0669902807136153 0.9465894406866386 1.0 1.0 6 P05556,O14936,P12814,Q14118,P11047 5
Metabolism of carbohydrates 0.2952217312887937 0.0652884087750595 0.9479443711118668 1.0 1.0 100 P54802,O00462,P16278,Q9BTX1,P09104,Q9BRR6,Q92621,Q9UBX3,P10253,P07686,O43252,P15586,P06865,Q8TB61,O00754,O43505,P60891 17
Foxo mediated transcription of oxidative stress metabolic and neuronal genes 0.2670750908056456 0.0649695139778639 0.9481982732757788 1.0 1.0 5 Q96ST3 1
Signaling by pdgfr in disease 0.2578028551947285 0.0579618633097165 0.9537790061002752 1.0 1.0 6 Q8TAF3 1
G alpha z signalling events 0.2563950029744118 0.0569177250343687 0.95461073466596 1.0 1.0 5 Q05655,P08754,P62873,P04899 4
G alpha s signalling events 0.2563950029744116 0.0569177250343684 0.9546107346659602 1.0 1.0 5 Q9Y3E5,P08754,P62873,P04899 4
Rna polymerase iii transcription 0.283665352306081 0.0567256032730349 0.954763778387107 1.0 1.0 15 Q9Y5Q9,Q9UKN8,Q9Y5Q8,Q12789,Q9BUI4 5
Trna modification in the mitochondrion 0.2600724427333923 0.0552393879953072 0.9559477497413456 1.0 1.0 7 Q7L0Y3,O75648,Q9Y2Z2 3
Dna double strand break response 0.3014996890826267 0.0522436905555312 0.9583345204168692 1.0 1.0 25 P38398,Q9NXR7,O95677,Q9UIG0,Q14676,O96028,Q99728 7
Adora2b mediated anti inflammatory cytokines production 0.2565476190476211 0.0509018840947888 0.9594037041674772 1.0 1.0 7 P62873,P10644,P08754,P04899,Q9Y3E5,P13861 6
Hiv transcription initiation 0.2828298137368734 0.048171402058764 0.961579641570419 1.0 1.0 16 P49848,P18074,P30876,P32780,Q92804,P19388,P19447 7
Deactivation of the beta catenin transactivating complex 0.2591599642538073 0.0451860178070203 0.9639590390408348 1.0 1.0 10 Q13547,Q04726,Q13363,P35222,P31751,Q9HCK8,Q15291,Q9UBL3,O14980 9
Synthesis of pa 0.2525364680006545 0.0416654680627745 0.9667653825370346 1.0 1.0 9 O15228,Q8NF37,Q8N2A8 3
Anti inflammatory response favouring leishmania parasite infection 0.2567768841227353 0.0409866264070871 0.9673065574848904 1.0 1.0 10 P62873,P10644,P08754,Q16539,P04899,P19174,P13861,Q9Y3E5,P35579 9
Pi metabolism 0.2931877988565964 0.039940006308271 0.968140956112957 1.0 1.0 22 Q10713,P42356,Q8N9F7,Q8IY17,Q9Y217 5
Rna polymerase i transcription 0.2972269082460207 0.038002320057951 0.9696858322272216 1.0 1.0 26 Q14839,Q13185,Q13547,Q92769,O94776,Q8WXI9,Q9H9Y6,O95602,Q13330,P17480,P32780,P18074,P19388,P19447 14
Pka mediated phosphorylation of creb 0.37325408618128 0.0378790127720933 0.969784146419955 1.0 1.0 2 P10644 1
Pka activation in glucagon signalling 0.37325408618128 0.0378790127720933 0.969784146419955 1.0 1.0 2 P10644 1
Creb1 phosphorylation through the activation of adenylate cyclase 0.37325408618128 0.0378790127720933 0.969784146419955 1.0 1.0 2 P10644 1
Maturation of sars cov 1 nucleoprotein 0.3684992570579515 0.0376507800382799 0.96996611998366 1.0 1.0 2 P49841 1
P75ntr recruits signalling complexes 0.3628528974739989 0.0374125200805255 0.9701560900795418 1.0 1.0 2 Q13501 1
Sumoylation of intracellular receptors 0.3402674591381892 0.0367449597396089 0.9706883601420871 1.0 1.0 2 O75925 1
Nonhomologous end joining nhej 0.2874811580007491 0.0354425864163965 0.9717268269786145 1.0 1.0 20 P38398,Q9NXR7,Q14676,O96028,Q92878,Q99728,P78527 7
Hemostasis 0.31354543342913 0.0342528250529899 0.9726755429280968 1.0 1.0 119 P42785,P07602,Q8NBX0,Q08380,Q96Q89,Q9NZJ7,P05067,Q92896,Q12846,Q96HP0,O43852,Q14185,P16615,P13473 14
E2f mediated regulation of dna replication 0.2513925094853728 0.0319845013341909 0.9744844107180042 1.0 1.0 10 Q9UBD5 1
Parasite infection 0.294039744398053 0.0317691403604313 0.9746561566332296 1.0 1.0 25 Q96F07,Q7L576,Q9UQB8 3
Dna replication initiation 0.236904761904764 0.0307070318476728 0.97550318320493 1.0 1.0 7 P56282,P49642,Q9NRF9,P09884,Q07864,Q9NR33 6
Signaling by gpcr 0.2764774794783787 0.0284399448689076 0.9773112656768216 1.0 1.0 42 P07602,P42892 2
Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.271859146523437 0.0256116955875612 0.9795670574010517 1.0 1.0 16 Q13951,Q14781,Q96GM5,Q969G3,Q8TAQ2,O14497,P67870,P51532,Q99496,O96019,Q92922,Q86U86,Q9HC52,Q12824,P19784 15
Sumoylation of dna damage response and repair proteins 0.2491195500281193 0.0252530167418062 0.9798531491751126 1.0 1.0 49 P49790,Q14781,P35658,Q8WUM0,P38398,P12270,Q8N3U4,P57740,Q9BTX1,O75694,P54132,Q96SB8,P49792,Q92621,P52948,Q14191,Q99567,Q14676,Q12769,Q8N1F7 20
Snrnp assembly 0.2802936815091175 0.0216702081843926 0.9827110286150532 1.0 1.0 40 P49790,P57740,Q99567,Q9BTX1,Q09161,O75694,P62316,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P52948,P12270 15
Signaling by ctnnb1 phospho site mutants 0.2245729952318831 0.0211814907455285 0.9831008792161908 1.0 1.0 7 P35222 1
Beta catenin phosphorylation cascade 0.2245729952318831 0.0211814907455285 0.9831008792161908 1.0 1.0 7 P35222 1
Disassembly of the destruction complex and recruitment of axin to the membrane 0.2245729952318831 0.0211814907455285 0.9831008792161908 1.0 1.0 7 P35222 1
Interactions of rev with host cellular proteins 0.289938286553142 0.0191340600711714 0.9847341603912478 1.0 1.0 34 P49790,P57740,Q99567,Q9BTX1,O75694,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P52948,P12270 13
Rhoq gtpase cycle 0.2823716407890989 0.0190859684957956 0.9847725249108814 1.0 1.0 21 Q86VI3,P27105,Q658P3,P02786,O00401 5
Hcmv late events 0.2857335391166231 0.0131401087294642 0.9895160118168848 1.0 1.0 36 P49790,P57740,Q99567,Q9BTX1,Q9H9H4,O75694,P49792,Q92621,P35658,Q8WUM0,Q12769,Q8N1F7,P52948,P12270,Q9BRG1 15
Translation of sars cov 2 structural proteins 0.2703914345505603 0.0107857014233132 0.9913944222069868 1.0 1.0 18 Q16706,Q9H0U3,P46977,Q10472 4
Rho gtpases activate iqgaps 0.2513042233237284 0.0104139417806932 0.9916910268213006 1.0 1.0 13 Q86VI3,P04350 2
Formation of the beta catenin tcf transactivating complex 0.2397361345517555 0.007783701179976 0.9937895677135368 1.0 1.0 11 P51532,P35222,Q13547,Q9Y4A5 4
Signaling by fgfr in disease 0.2763918009271215 0.006546115461872 0.994776992842159 1.0 1.0 21 O95684 1
Cell junction organization 0.2639533343130685 0.0051720470449763 0.9958733219132304 1.0 1.0 17 P19022,P55196,Q03001 3