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bd35244 verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Protein localization 0.6130700854934589 3.975941714890328 7.010129458917547e-05 0.0940545516497344 0.0987727240761496 83 Q13505,O60830,Q99595,Q9Y5J9,Q15067,P05067,Q9BTZ2,P50402,Q9UKG9,Q9NX63,P21796,P51648,Q5JRX3,Q9NR77,Q9Y3D6,O15254,P09601,Q9Y5J7,Q9Y512,Q9Y584,Q2T9J0,Q8N4H5,Q3ZCQ8,Q9NS69,Q7L5D6,Q15388,O75874,Q9BY49,O15228,P06576,P39210 31
Ire1alpha activates chaperones 0.7256548148067731 3.4698900556398313 0.0005206714472889 0.5199270102324346 0.2131330158726281 26 Q9Y4L1,Q9Y5M8,O95070,Q13217,Q9NWM8,Q14554,P43307,Q969H8,O14773,Q9HCU5 10
Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.5465421572598083 3.4370805517357117 0.0005880206989172 0.5634117964406465 0.2131330158726281 75 Q7L592,O75438,P13073,O14949,P20674,O75380,Q8N8Q8,P21912,P03886,O75306,O96000,O95139,P47985,O43676,Q9Y6M9,P22695,O75489,Q9UDW1,O43674,O43819,O95168,P00403,O95167,O75880,O14548,P06576,Q8N183,P24539,O75964,O00217,O75251,P56556,Q86Y39 33
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.7754431414598768 3.3951980792687486 0.0006857896551337 0.6196293501255415 0.2131330158726281 20 P14314,P07942,P05067,Q07065,Q13217,P07237,Q02818,Q15293,O43852,Q5JRA6,P14625,Q9BTY2 12
N glycan trimming in the er and calnexin calreticulin cycle 0.8063232118673064 3.335894053560103 0.0008502555997771 0.6983596111049325 0.2131330158726281 17 P14314,P30101,Q13724,Q9UKV5,Q14165,Q9UBV2,Q9NYU2,P27824,Q9BUN8,Q13438,O60858,Q14697 12
Mitochondrial protein import 0.6687750234662624 3.3177081320351727 0.0009075926864696 0.7217899181295475 0.2131330158726281 38 Q13505,Q9Y5J9,Q99595,O60830,Q5JRX3,Q15388,Q9Y5J7,Q9Y512,Q9Y584,Q9NX63,Q8N4H5,Q3ZCQ8,P06576,P21796,Q9NS69 15
Sphingolipid metabolism 0.6612103768342061 3.13619783518909 0.0017115370547953 0.9105094102317366 0.2858851037102277 29 P51648,P27544,Q9NZJ7,P04062,P17900,P07602,P06280,Q8NBJ7,O95470,Q16739,Q16880,Q96G23,Q06136,Q9NRA0 14
Respiratory electron transport 0.5593903490847915 3.1281250548100843 0.0017592531204302 0.9163380173857032 0.2858851037102277 64 Q7L592,O75438,P13073,O14949,P20674,O75380,Q8N8Q8,P21912,P03886,O75306,O96000,O95139,P47985,O95169,O43676,Q9Y6M9,P22695,O75489,Q9UDW1,O43674,O43819,O95168,P00403,O95167,O75880,O14548,Q8N183,O75251,O00217,P56556,Q86Y39 31
Antigen presentation folding assembly and peptide loading of class i mhc 0.7089766508602335 2.954271301281648 0.0031340835068129 0.988000113533537 0.3167740476064937 19 P30101,P30511,Q6P179,O15533,P51572,P10321,P27824,P27797,Q9NZ08 9
Calnexin calreticulin cycle 0.8538398018166908 2.8517228478661063 0.0043482995029737 0.9978453203505808 0.3167740476064937 10 P14314,P30101,Q9UKV5,Q9UBV2,Q9NYU2,P27824,Q13438,O60858,Q14697 9
Peptide hormone metabolism 0.6839121407421481 2.7597612393375215 0.00578436191523 0.9997180635840592 0.3167740476064937 18 O00471,P67812,Q15005,Q8NEW0,Q96HE7,O75787 6
Sphingolipid de novo biosynthesis 0.8017990001843048 2.6904815212230218 0.007134898634602 0.9999584705402704 0.3167740476064937 11 P51648,P27544,O95470,Q96G23,Q9NRA0 5
Unfolded protein response upr 0.557637485655336 2.5720898505538012 0.0101086653085333 0.9999993935161188 0.3263352366049881 44 Q9Y4L1,Q9Y5M8,O95070,Q13217,Q9NWM8,Q15084,O14653,Q14554,P43307,Q969H8,P14625,O14773,Q9HCU5 13
Collagen biosynthesis and modifying enzymes 0.7707191588364986 2.537334750084702 0.0111700088877133 0.9999998662244508 0.3305470081796913 11 P07237,O75718,Q32P28,P13674 4
Extracellular matrix organization 0.5668939752909241 2.5031860652820184 0.0123080818663658 0.999999973594543 0.3305470081796913 34 P78536,O75718,P07942,P05067,O15460,Q02809,P07237,Q32P28,P11047,P13674,O14936,Q92542,O60568,P35613 14
Slc mediated transmembrane transport 0.5741512129952141 2.4960667592856427 0.0125578964949935 0.9999999815114704 0.3305470081796913 27 Q70HW3,P04920,P11166,Q9UBX3,Q8NEW0,Q8TB61,P53985,Q01650,P36404,P35613,O00400 11
Complex i biogenesis 0.559616290182337 2.481862444983909 0.0130697717462082 0.999999991095502 0.3305470081796913 37 Q7L592,O75438,O75380,P03886,O75306,O96000,O95139,O95169,O43676,Q9Y6M9,O75489,O43674,O95168,O95167,Q8N183,O75251,O00217,P56556,Q86Y39 19
Translation of sars cov 2 structural proteins 0.6331841275225163 2.4472316335877142 0.0143958287791539 0.999999998660728 0.3406205310650327 18 P14314,Q13724,P04843,P04844,Q10472,P27824,P46977,Q14697 8
The citric acid tca cycle and respiratory electron transport 0.4928015108484536 2.438544962752453 0.0147465240560447 0.9999999991888564 0.3406205310650327 110 Q7L592,O75438,P13073,O14949,P20674,O75380,Q96I99,Q8N8Q8,P53985,P21912,P35613,P21796,P03886,O75306,O96000,O95139,P47985,O43676,Q9Y6M9,P22695,O75489,Q9UDW1,Q8NCN5,O43674,P08559,O43819,Q15118,O95168,P00403,O95167,O75880,Q8N183,P06576,O14548,P48735,P24539,O75964,Q9P0J1,O00217,P48163,O75251,Q13423,P56556,Q86Y39,Q15120,P23368 46
Mitochondrial calcium ion transport 0.6228450968124407 2.42040360246804 0.0155032891810629 0.9999999997252702 0.3467322929542485 19 Q8IYU8,Q9Y4W6,P45880,Q99623,Q9UJZ1,Q9Y277,Q9NWR8,Q9H300,Q9H4I9,O75439,Q96TA2,P21796 12
Glycerophospholipid biosynthesis 0.5533627030400965 2.409018733713279 0.0159954768941799 0.999999999864198 0.3493387775185618 35 Q9UG56,Q8IV08,Q96N66,Q9HCL2,Q9Y6K0,Q8NCC3,O95674,Q92604,Q8N2A8,O15228,Q9BVG9 11
Gpcr ligand binding 0.7592448698229187 2.399449116194235 0.0164197617340109 0.9999999999260394 0.3493387775185618 10 Q9NZJ7,P05067,P07602,P04083,Q9BYT8,P22466 6
Er quality control compartment erqc 0.9169873556899348 2.386425995204101 0.0170130311167808 0.9999999999683922 0.3493387775185618 5 Q13438,O60858,Q9UKV5,Q9UBV2 4
Collagen formation 0.7024454881183715 2.3599784427991244 0.0182759970505999 0.9999999999948348 0.3576511089485453 13 P07237,O75718,Q32P28,P13674 4
Cargo concentration in the er 0.6162579453133398 2.340194837206766 0.0192736821248118 0.9999999999987672 0.3622891189884876 18 P49755,P49257,Q5JRA6,Q96PC5,Q8NI22,Q9HCU5 6
Translation of sars cov 1 structural proteins 0.7948756014780414 2.335036775236113 0.0195414996757452 0.999999999999161 0.3622891189884876 8 P14314,Q10472,Q13724,P27824 4
Maturation of sars cov 2 spike protein 0.712011829211187 2.322242097086516 0.020219903414242 0.9999999999996836 0.3649734793488106 12 P14314,Q13724,P04843,P04844,P27824,P46977,Q14697 7
O linked glycosylation 0.8294604854927738 2.317741360344842 0.020463381737797 0.9999999999997772 0.3649734793488106 7 Q8N4A0,Q9Y2G5,Q8NAT1 3
Class a 1 rhodopsin like receptors 0.7855112212253774 2.2917409686693557 0.021920594840888 0.9999999999999728 0.372121905190497 8 Q9NZJ7,P05067,P07602,P04083,Q9BYT8,P22466 6
Peptide ligand binding receptors 0.7855112212253774 2.2917409686693557 0.021920594840888 0.9999999999999728 0.372121905190497 8 Q9NZJ7,P05067,P07602,P04083,Q9BYT8,P22466 6
Response to elevated platelet cytosolic ca2 0.532537176585672 2.2777137504817833 0.0227436379400449 0.9999999999999916 0.3770092453826277 38 Q9NTK5,Q8NBX0,Q9Y6I9,P07602,Q9BWS9,O43852,Q08380,Q8NBM8,Q8NBF2,Q96JJ7,O94919 11
Interferon gamma signaling 0.6703413531241305 2.267374226331743 0.0233673745840581 0.9999999999999966 0.3796883391547515 14 P10321,P30511 2
Synthesis of pa 0.7313127455338823 2.2608677387463008 0.0237674483968834 0.999999999999998 0.379719844463983 10 Q9HCL2 1
Class i peroxisomal membrane protein import 0.7457753107608835 2.2152098215202103 0.0267456660649501 1.0 0.3877925872758053 9 P51648,Q9NR77 2
Interferon alpha beta signaling 0.6921182149243418 2.136490565752456 0.0326394491395207 1.0 0.3997215061837301 11 P30511 1
Ion transport by p type atpases 0.6915417941056519 2.133477725599862 0.032885556982783 1.0 0.3997215061837301 11 Q9HD20,Q13555 2
Endosomal vacuolar pathway 0.8528089660953415 2.1209829724914746 0.033923235376009 1.0 0.3997215061837301 5 P10321,P30511 2
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.6720308258240443 2.109071229105703 0.0349384338312841 1.0 0.3997215061837301 12 P51648,P05067,P50402,P09601 4
Pink1 prkn mediated mitophagy 0.7172334326861676 2.075695071684411 0.0379221620476748 1.0 0.3997215061837301 9 Q8N4H5,Q15388,Q9NS69 3
Maturation of sars cov 1 spike protein 0.8397531024277289 2.0660379006988165 0.0388249010248109 1.0 0.3997215061837301 5 P14314,Q13724,P27824 3
Insulin processing 0.6599022721059153 2.0433170511859116 0.0410210627390448 1.0 0.3997215061837301 12 O00471,Q96HE7,Q8NEW0 3
Basigin interactions 0.7303460579811571 2.0321174544748946 0.0421417667739787 1.0 0.3997215061837301 8 Q01650,P35613 2
Purine salvage 0.7656143669843197 2.031420694800802 0.042212336869259 1.0 0.3997215061837301 7 P55263 1
Processing of smdt1 0.6287051613753004 2.02964253282152 0.0423928882247641 1.0 0.3997215061837301 14 Q8IYU8,Q9Y4W6,Q99623,Q9NWR8,Q9H4I9,Q9H300,Q96TA2,Q9UJZ1,O75439 9
Glycosaminoglycan metabolism 0.5512860651710174 2.0226050946733967 0.0431138785251945 1.0 0.3997215061837301 21 O60512,Q8NCH0,Q93063,P34059,P15586,Q96L58,Q8TB61,P54802,Q9P2E5,P08236 10
Mitochondrial biogenesis 0.498277028552508 1.9748557419834227 0.0482845211476945 1.0 0.4067029979297684 36 Q13505,P48735,O00411,P24539,O75964,P06576,Q9Y512,P54619,Q9NX63,Q96RR1,Q86X55,Q5XKP0,Q04837 13
Glycosphingolipid metabolism 0.5597588941852024 1.9725225093357583 0.0485499893077954 1.0 0.4067029979297684 18 Q9NZJ7,P07602,P17900,P04062,Q8NBJ7,Q16739,Q16880 7
Rhog gtpase cycle 0.492185242643527 1.965741959631368 0.0493284252748251 1.0 0.4067029979297684 40 O15173,P49257,Q8TAA9,Q14185,Q86XL3,P42167,Q14739 7
Rac2 gtpase cycle 0.4921495789983753 1.9654375929820944 0.049363612043846 1.0 0.4067029979297684 40 Q13505,Q86Y07,O15173,P50402,P49257,Q8TAA9,Q14185,Q86XL3,P42167,Q14739 10
Ecm proteoglycans 0.7797957926019016 1.9372486164507572 0.0527149600179481 1.0 0.4244307352302227 6 P07942,P05067,P11047 3
Gamma carboxylation hypusine formation and arylsulfatase activation 0.6386641342611622 1.926957095138384 0.0539849771224152 1.0 0.4278954535081924 12 Q8NBJ7,O60725,P38435 3
Mitophagy 0.6078630505139916 1.9081009769561983 0.0563781664790032 1.0 0.434875676687997 14 Q8N4H5,Q15388,Q9NS69 3
Post translational modification synthesis of gpi anchored proteins 0.6833843384940997 1.9073029460297872 0.0564813689381855 1.0 0.434875676687997 9 Q969N2,Q96S52,Q5H8A4,Q92643,O43292 5
Metabolism of porphyrins 0.6599891578898999 1.896266749063096 0.0579247807541476 1.0 0.4411676545005082 10 P22830,P30519,Q7KZN9,P09601 4
Nucleotide salvage 0.658405832527927 1.8879985127654373 0.0590261501067448 1.0 0.4471389543032444 10 P55263 1
Attachment of gpi anchor to upar 0.8403407529540946 1.8682547444227464 0.0617265713973802 1.0 0.4540650384827667 4 Q96S52,Q92643,O43292 3
Peroxisomal protein import 0.4989792756543821 1.8671974815816472 0.0618740151800505 1.0 0.4540650384827667 26 Q15067,O75874,Q9BTZ2,O15254,Q9UKG9,Q9BY49,O15228,Q2T9J0 8
Phospholipid metabolism 0.4599367103605384 1.86164542403584 0.0626530860503655 1.0 0.455161246965365 52 Q8IV08,Q96N66,Q9HCL2,Q9Y6K0,Q8NCC3,Q9BVG9,O95674,Q92604,Q8N2A8,O15228,Q9NZC3,Q9UG56 12
Mucopolysaccharidoses 0.7916221367153388 1.8608111389890356 0.0627708519187977 1.0 0.455161246965365 5 P34059,P08236,P54802 3
Alpha oxidation of phytanate 0.8319255240208807 1.8333135702216388 0.0667559524624976 1.0 0.4748237480872823 4 P51648 1
Cristae formation 0.5236275259959381 1.8280205444019195 0.0675464683897169 1.0 0.4748237480872823 21 Q13505,P24539,O75964,P06576,Q9Y512,Q9NX63,Q5XKP0 7
Vitamin d calciferol metabolism 0.829624730815714 1.8237428366511172 0.0681909594978531 1.0 0.4748237480872823 4 P38435 1
Abc family proteins mediated transport 0.4440770709614667 1.8142700113041352 0.069636166122599 1.0 0.4762978546929226 57 P49721,O75027,O75477,P60900,P28070,Q9NUT2,Q9UBV2,P08183,P28074,O94905,P28072,Q99436,Q9BUN8,Q13438 14
Dna damage recognition in gg ner 0.5307357414013871 1.8081902377222565 0.0705768974797003 1.0 0.4804002345357378 19 Q92905,Q9UGN5,Q7L5N1 3
Synthesis of pg 0.8239874866956634 1.8002620415393338 0.0718192715408791 1.0 0.484178725364109 4 Q8N2A8 1
Sars cov 2 infection 0.479940540835915 1.7730251006188094 0.076224547705832 1.0 0.5114304177024639 28 P14314,Q13724,P04843,P04844,Q10472,P27824,P46977,Q14697 8
Non integrin membrane ecm interactions 0.6751205777322364 1.7644990623968757 0.0776479930693327 1.0 0.5160661426164618 8 P07942,O14936,P11047 3
Depolymerisation of the nuclear lamina 0.6739420639084378 1.7587071777270864 0.078627257621276 1.0 0.5167216243755813 8 P02545,P42167,P50402 3
Peroxisomal lipid metabolism 0.6056443150180091 1.743006272577181 0.0813325191483775 1.0 0.5167216243755813 12 P51648,Q9BY49,Q15067,O15254 4
Laminin interactions 0.7643014311055917 1.7425405006229362 0.0814139110087857 1.0 0.5167216243755813 5 P07942,P11047 2
Disorders of transmembrane transporters 0.3980216238135566 1.7301741382919449 0.0835991674523966 1.0 0.5235165641796746 82 P49721,P60900,P11166,Q9UBV2,P53985,P35613,P28070,O14678,Q9BTX1,P28072,Q9NP58,O75477,O94905,Q13438,P28074,Q99436,Q8TEM1,Q9BUN8,Q7Z3B4,O00400 20
O linked glycosylation of mucins 0.7602212661432706 1.7247742832804245 0.0845681580086659 1.0 0.5264207034925987 5 O43505,Q8N4A0,Q10472 3
Heme degradation 0.8056141559290924 1.723433568525062 0.0848101488238608 1.0 0.5264207034925987 4 P30519 1
Abc transporter disorders 0.453518288335803 1.7158780427388007 0.086184366279026 1.0 0.5277418787750671 47 P49721,O75477,P60900,P28070,O14678,Q9UBV2,P28074,O94905,P28072,Q99436,Q9BUN8,Q13438 12
Transport of bile salts and organic acids metal ions and amine compounds 0.7581594508974779 1.7157867237113205 0.0862010849720535 1.0 0.5277418787750671 5 Q8NEW0,P35613 2
Ra biosynthesis pathway 0.7543526879230695 1.699175751839337 0.0892860737307548 1.0 0.5385847250810036 5 Q9BTZ2 1
Formation of atp by chemiosmotic coupling 0.6093896028414887 1.6931984176993984 0.0904177056882074 1.0 0.539824353028323 11 P06576,O75964 2
Signaling by retinoic acid 0.5819217712271654 1.682390132792806 0.0924932134925895 1.0 0.5452842586236765 13 O94788,P08559,Q9BTZ2,Q15118,Q15120 5
Transcriptional activation of mitochondrial biogenesis 0.580006825144683 1.6712020069559952 0.0946817839879246 1.0 0.5550182118708884 13 P48735,O00411,P06576,Q86X55,Q04837 5
Met activates ptk2 signaling 0.7455606239993782 1.6607282248327369 0.0967680420759484 1.0 0.5587957839549648 5 P07942 1
Defects in cobalamin b12 metabolism 0.7173243827849765 1.6587257314437374 0.0971710718729237 1.0 0.5588328174242838 6 Q96EY8,O14678,Q9NPF0 3
Metabolism of cofactors 0.6494414429918061 1.6375750444400108 0.1015103724427013 1.0 0.5657454229218432 8 P35270,O75874,Q86YH6,P00374 4
Diseases associated with n glycosylation of proteins 0.6805362222360362 1.6357430458015867 0.1018933763799421 1.0 0.5657454229218432 7 Q9BT22,Q96AA3,Q13724 3
Hedgehog ligand biogenesis 0.4503355617581628 1.6335411824417558 0.1023552266866367 1.0 0.5657454229218432 43 P78536,P49721,P07237,P28070,Q9UBV2,P28074,P28072,Q13438 8
Defective cftr causes cystic fibrosis 0.4481926892227102 1.6261557265833348 0.1039165317665706 1.0 0.5657454229218432 44 P49721,O75477,P60900,P28070,Q9UBV2,P28074,O94905,P28072,Q9BUN8,Q13438 10
Egr2 and sox10 mediated initiation of schwann cell myelination 0.6466090997603429 1.623485618088219 0.1044856353210428 1.0 0.5657454229218432 8 Q9NR77 1
Initiation of nuclear envelope ne reformation 0.5342472398491344 1.6174124716047955 0.1057892754224367 1.0 0.5657454229218432 16 Q86XL3,Q14739,P42167,P50402 4
Antigen processing cross presentation 0.4262135118236441 1.6136913253855485 0.1065943964662914 1.0 0.5657454229218432 56 Q9UIQ6,P30101,P49721,P30511,P60900,O15533,P28070,P61619,P10321,P28074,P28072 11
N glycan antennae elongation in the medial trans golgi 0.7790264824124347 1.6115094711071414 0.1070687245885548 1.0 0.5657454229218432 4 O60512 1
Incretin synthesis secretion and inactivation 0.7332671658267307 1.606782658226953 0.1081020537277241 1.0 0.5657454229218432 5 P67812 1
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.7332671658267307 1.606782658226953 0.1081020537277241 1.0 0.5657454229218432 5 P67812 1
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.671646620801206 1.593545369798851 0.111037898775943 1.0 0.5657454229218432 7 P30511 1
Vldl assembly 0.9447953858829978 1.590482904297227 0.1117259961298826 1.0 0.5657454229218432 2 P07237 1
Sulfide oxidation to sulfate 0.9439714364185656 1.587119020164511 0.1124856908696845 1.0 0.5657454229218432 2 Q9UBX3 1
Dap12 interactions 0.7285040848502264 1.5858258123800315 0.1127788285667981 1.0 0.5657454229218432 5 P10321 1
The nlrp3 inflammasome 0.7163290976512824 1.5321250255597902 0.125491585300824 1.0 0.5993818430130884 5 P05067,P09601 2
Inflammasomes 0.7163290976512824 1.5321250255597902 0.125491585300824 1.0 0.5993818430130884 5 P05067,P09601 2
Heparan sulfate heparin hs gag metabolism 0.6572714673012364 1.5250082813228685 0.1272570321162853 1.0 0.6057606697697502 7 P54802,P08236,Q93063 3
Beta oxidation of butanoyl coa to acetyl coa 0.7573509205825734 1.5196951919705834 0.1285876005664077 1.0 0.6079863395908338 4 P30084,P40939,P16219 3
Ion channel transport 0.4472470155919891 1.5106377497952794 0.1308807705181298 1.0 0.6082445674468117 30 Q12797,Q4KMQ2,Q9C0H2,Q9HD20,P05026,Q15904,P16615,P27105,P98194,Q9Y487,Q5EBL8,P36543,Q13555,P05023,P51797 15
Diseases of carbohydrate metabolism 0.5873460321422238 1.5095550015994177 0.1311570107498147 1.0 0.6082445674468117 10 P34059,P10253,P08236,P54802 4
Synthesis secretion and deacylation of ghrelin 0.9183787689868178 1.496792960178081 0.1344471386433439 1.0 0.6085167732458384 3 P67812 1
Synthesis of pe 0.7508723493657821 1.4921687587217274 0.1356549101417592 1.0 0.6085167732458384 4 Q9UG56 1
Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.750788800296837 1.49181354516757 0.1357480320079673 1.0 0.6085167732458384 4 P67812 1
Sars cov 1 infection 0.4867604040160097 1.47374579098116 0.140550048783842 1.0 0.6131243153104815 18 P14314,Q10472,Q13724,P27824 4
Cobalamin cbl vitamin b12 transport and metabolism 0.6404284610699059 1.4442698650740078 0.1486630790426195 1.0 0.6189582011130356 7 Q96EY8,O14678,Q9NPF0 3
Transport of inorganic cations anions and amino acids oligopeptides 0.5530500591284274 1.4428061792010596 0.1490750780076413 1.0 0.6189582011130356 12 Q70HW3,P04920,P30825,Q9UBX3,P55011,Q01650 6
Platelet homeostasis 0.5497959607606303 1.4239684848926424 0.1544555951733761 1.0 0.6289824670499624 12 Q16537 1
Rhod gtpase cycle 0.4362007098406992 1.4205517810069823 0.1554471049329784 1.0 0.6300449538312959 31 O15173,P50402,P49257,Q8TAA9,P42167,Q14739 6
Cell surface interactions at the vascular wall 0.4749303928045921 1.4160428778304457 0.1567629508908414 1.0 0.6323524968627847 19 P62993,P53985,Q01650,P14174,P06756,P35613 6
Synthesis of very long chain fatty acyl coas 0.586667341521239 1.4097714329981916 0.1586071843632297 1.0 0.63487932604486 9 Q9UKU0,Q9P035,Q6Y1H2,Q53GQ0,Q4G176 5
Interleukin 4 and interleukin 13 signaling 0.5339808920910764 1.3987012058166668 0.1619026024936767 1.0 0.644408946083589 13 P14625,P09601,P04083,P08670 4
Rac3 gtpase cycle 0.4268435404363787 1.3753671241435956 0.1690176559372773 1.0 0.6505009407670777 38 O15173,Q9UQB8,P49257,Q8TAA9,P42167,Q14739 6
Degradation of cysteine and homocysteine 0.6552041330922285 1.3753440717496832 0.1690247992508777 1.0 0.6505009407670777 6 Q9UBX3 1
Pyruvate metabolism 0.4724854797520197 1.3732929887744474 0.1696612813572555 1.0 0.6505009407670777 18 Q15120,Q8NCN5,P08559,Q9P0J1,Q15118,P53985,P35613,P21796 8
Miscellaneous transport and binding events 0.5966835018118726 1.3725360442415515 0.1698966261194354 1.0 0.6505009407670777 8 Q9UEY8,Q8N4V1,Q9H0U3 3
Proton coupled monocarboxylate transport 0.8884921724800872 1.3605661643087852 0.1736508304039552 1.0 0.6557785726500484 2 P35613 1
Cardiac conduction 0.5486648225810231 1.354854810492628 0.1754638196515743 1.0 0.6557785726500484 11 P16615,O43865,Q13555 3
Ion homeostasis 0.5486648225810231 1.354854810492628 0.1754638196515743 1.0 0.6557785726500484 11 P16615,O43865,Q13555 3
Role of phospholipids in phagocytosis 0.7156830387126517 1.342152232866438 0.1795466408166151 1.0 0.6674966145398697 4 Q8IV08 1
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.6699278794623732 1.3260255946517645 0.1848312196989361 1.0 0.6712040942159819 5 P36404,P12236,P12235 3
Transport of vitamins nucleosides and related molecules 0.5688362978609507 1.3158162469739518 0.1882357247929198 1.0 0.6817754181509565 9 P36404,Q8TB61,O00400 3
Nuclear signaling by erbb4 0.7083682663934496 1.310895907781003 0.1898929336161474 1.0 0.6842944845656055 4 Q92542,P78536 2
Beta oxidation of pristanoyl coa 0.6645388881596699 1.3019812995951343 0.1929227783505473 1.0 0.6899192758779729 5 O15254 1
Heme biosynthesis 0.6370931383014269 1.2918491680255937 0.1964093841765457 1.0 0.6942825999252276 6 P22830,Q7KZN9 2
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.6606213503234795 1.2844934716030063 0.1989693463843826 1.0 0.6973826095910328 5 P02654,Q9BZK7,Q8NB78 3
Pre notch processing in golgi 0.659666126880591 1.2802283930274412 0.2004648229956696 1.0 0.6974195940762925 5 Q9UBV2 1
Phase i functionalization of compounds 0.5037781192602122 1.27724348752192 0.2015162982377809 1.0 0.6976325902138412 14 P07099,P16435 2
Plasma lipoprotein remodeling 0.8648722878330093 1.2644233019747653 0.2060781335582096 1.0 0.7047672091832945 2 P07237 1
Metabolism of folate and pterines 0.5726399313602539 1.2502548121206103 0.2112064797556703 1.0 0.7085474523231892 8 P41440,P00374,Q9H2D1 3
Plasma lipoprotein assembly 0.6933247795971651 1.2465865851996587 0.2125491230217699 1.0 0.7104461511557173 4 P07237 1
Wnt ligand biogenesis and trafficking 0.6238002510825176 1.2304118940851287 0.2185429015984765 1.0 0.713659579127532 6 Q5T9L3 1
Regulated proteolysis of p75ntr 0.8549848942598162 1.2243125777501904 0.2208343339244882 1.0 0.713659579127532 2 P78536 1
Atf6 atf6 alpha activates chaperone genes 0.8519637462235621 1.2120770102595604 0.2254829030938827 1.0 0.7188217426364578 2 P14625 1
Atf6 atf6 alpha activates chaperones 0.8519637462235621 1.2120770102595604 0.2254829030938827 1.0 0.7188217426364578 2 P14625 1
Acyl chain remodelling of pg 0.8494918978302668 1.2020739452350289 0.2293348799929626 1.0 0.7228373001857356 2 Q92604 1
Rnd2 gtpase cycle 0.44412331802662 1.1935617394190086 0.232649447932161 1.0 0.7251835390898511 19 P51648,Q07065,O43396,P38159,Q8TAA9 5
Citric acid cycle tca cycle 0.4434443696350947 1.1886195572770282 0.2345894083505781 1.0 0.7251835390898511 19 P48735,Q13423 2
Ras processing 0.6391597521251172 1.1886117331524024 0.2345924886195836 1.0 0.7251835390898511 5 O60725 1
Pyruvate metabolism and citric acid tca cycle 0.4051175045213246 1.1738547795238952 0.2404531979088391 1.0 0.7285990448463534 37 P48735,Q15120,Q8NCN5,P08559,Q9P0J1,P48163,Q13423,Q15118,P53985,P23368,P21912,P35613,P21796 13
Cellular response to chemical stress 0.3511426726485307 1.1570795230594595 0.247239871880837 1.0 0.7306345303680251 82 P49721,P60900,P07237,P28070,Q8TCT9,P09601,O43819,P28074,P28072,P00403,Q8N8Q8,P30519,Q99436 13
Purinergic signaling in leishmaniasis infection 0.6685598457940436 1.140784666128525 0.2539595431922605 1.0 0.7362736550573974 4 P09601 1
Regulation of pyruvate dehydrogenase pdh complex 0.5184714816805447 1.1314459565011794 0.2578674378988168 1.0 0.7401299598283843 10 P08559,Q15118,Q9P0J1,Q15120 4
Lipophagy 0.6653690261603291 1.1271722824996162 0.2596696470027981 1.0 0.7401299598283843 4 P11142,P54619 2
Formyl peptide receptors bind formyl peptides and many other ligands 0.8208791208791213 1.1213119617135543 0.262155095671897 1.0 0.7411705422559662 3 P04083,P05067 2
Synthesis of glycosylphosphatidylinositol gpi 0.8250480637187549 1.1036084229213456 0.269763035842534 1.0 0.7511780978302973 2 Q5H8A4 1
Cytoprotection by hmox1 0.3423854532063185 1.0969907144362745 0.272645451236372 1.0 0.75232876619396 72 P49721,P60900,Q8TCT9,P28070,P09601,O43819,P28074,P28072,Q8N8Q8,P00403,P30519 11
Noncanonical activation of notch3 0.823125514968415 1.0959046419499237 0.2731205074522416 1.0 0.75232876619396 2 Q92542 1
Hs gag degradation 0.8105234461661236 1.0817818111813189 0.2793494905630722 1.0 0.7540295636079861 3 P08236 1
Asparagine n linked glycosylation 0.4014050922827569 1.0628495130815323 0.2878502015320865 1.0 0.7569401490727165 137 O60512,P04843,O14653,P04844,Q9UBV2,Q8NI22,Q96PC5,P46977,P24390,Q86YN1,P27797,Q9HCU5,Q9BT22,Q9UKV5,P04066,O60476,Q9NYU2,Q9UJ70,O60858,Q14697,P14314,Q9BVK6,Q5JRA6,Q13438,Q13630,P30101,Q13724,P49755,Q9BUN8,Q9H0U3,Q14165,O75935,P49257,P27824,Q96AA3 35
Nicotinate metabolism 0.6103107274042361 1.0598133140642592 0.2892295384936068 1.0 0.7569401490727165 5 Q4G0N4 1
Activated notch1 transmits signal to the nucleus 0.6395444733892578 1.017334001635669 0.3089945667315037 1.0 0.7788431923518583 4 P78536 1
Keratan sulfate biosynthesis 0.7900112861910673 1.0039286409289925 0.3154130102986738 1.0 0.784697229810641 3 O60512 1
Stimuli sensing channels 0.4914791962817233 0.981740285077649 0.3262278134608471 1.0 0.7973326079779863 10 Q12797,P27105,P51797 3
Transport of small molecules 0.4248227793330763 0.9728672135089436 0.3306193018685395 1.0 0.7973326079779863 171 P49721,O75027,P45880,P60900,Q9HD20,P16615,Q9UBV2,Q9UBX3,Q8N4V1,Q8TB61,Q13555,P53985,P35613,P21796,Q99623,Q8WTV0,P07237,P28070,Q9NUT2,P09601,P08183,Q8NEW0,P28072,P51797,Q9NP58,O75477,P04920,P02654,Q9H4I9,P61916,O94905,P36404,Q13438,P30519,Q12797,Q6PIU2,Q70HW3,Q9H0U3,Q9BU23,P28074,Q99436,Q9BUN8,Q01650,O00400 44
Keratan sulfate keratin metabolism 0.5183387269733951 0.9727064202513852 0.3306992334452039 1.0 0.7973326079779863 8 O60512,P34059,P15586 3
Abc transporters in lipid homeostasis 0.7912661356770105 0.9693799822590388 0.3323556361923727 1.0 0.7973326079779863 2 P40855 1
Rhoa gtpase cycle 0.3695744557380673 0.968788041556127 0.3326509543280456 1.0 0.7973326079779863 52 O15173,P49257,Q8TAA9,P42167,P41440,Q86VI3,P30519 7
Cholesterol biosynthesis 0.4049090409852909 0.9488323511113566 0.342705885219472 1.0 0.8021139406548771 21 Q15392,P37268,P48449,Q9H2C2,Q14739 5
Beta oxidation of hexanoyl coa to butanoyl coa 0.5833871358909927 0.9402313300028068 0.3470989145680665 1.0 0.8053121124229998 5 P30084,P40939,P16219 3
Interaction between l1 and ankyrins 0.6196757350920711 0.9334463493609274 0.3505895589196628 1.0 0.8053121124229998 4 Q01082,Q13813,O15020 3
Syndecan interactions 0.5577275161656716 0.925065687217863 0.354931740109782 1.0 0.8053121124229998 6 O14936 1
Pregnenolone biosynthesis 0.5793010716570852 0.9221771838278848 0.3564361621951919 1.0 0.8053196964460978 5 P30536,O95772 2
Muscle contraction 0.3776486513661591 0.9141312228977096 0.36064789801311 1.0 0.8053196964460978 27 Q12797,P08670,P16615,P04083,Q13555,O43865 6
Ubiquinol biosynthesis 0.764003444308679 0.9063437798877348 0.3647539198035392 1.0 0.8053196964460978 3 Q86YH6 1
Bicarbonate transporters 0.77286459763801 0.8975187432097853 0.3694421764714493 1.0 0.8053196964460978 2 P04920 1
Met promotes cell motility 0.4756601040300979 0.8940850773749527 0.3712763728890849 1.0 0.8053196964460978 10 P62993,P07942 2
Organelle biogenesis and maintenance 0.3599341824554993 0.8847472945102497 0.3762929414970817 1.0 0.8053196964460978 110 Q13505,Q9Y366,Q96CS2,P54619,Q9NX63,Q5XKP0,Q9Y512,O43924,O43805,Q86X55,O94927,Q04837,A6NIH7,Q96RR1,P06576,Q9UPN4,O00471,P48735,Q15154,O95684,Q9H6D7,Q15051,O00411,P24539,Q96RK4,O75964,Q6NUS6,O75935,Q92973 29
Rac1 gtpase cycle 0.3646935097969573 0.883481127769288 0.3769763747281269 1.0 0.8053196964460978 49 Q9UQB8,P50402,Q8TAA9,Q14185,P42167,Q86VI3,Q14739,Q9Y2I1 8
Nr1h2 and nr1h3 mediated signaling 0.5226313036336816 0.8735790859594899 0.3823475197962183 1.0 0.8089722331072425 7 P02654,O00767,Q8NB78 3
Receptor type tyrosine protein phosphatases 0.7610546553144715 0.8519903564187694 0.3942194444985349 1.0 0.8155262723306148 2 P10586 1
Dopamine neurotransmitter release cycle 0.7610546553144686 0.8519903564187594 0.3942194444985405 1.0 0.8155262723306148 2 O14936 1
Degradation of the extracellular matrix 0.4669541943930445 0.8459709938162704 0.3975689258258046 1.0 0.8156744453840685 10 Q92542,P78536,P07942,P35613 4
Diseases of glycosylation 0.3862404630983082 0.829103199652704 0.4070460133608775 1.0 0.8204976149148447 22 Q9BT22,Q13724,Q8NCH0,Q93063,Q9BV10,Q96L58,Q96AA3 7
Signaling by hedgehog 0.3400899353374287 0.8148795200192146 0.4151412771321678 1.0 0.8272824516222038 62 P78536,P49721,P07237,P28070,Q9UBV2,P28074,P28072,Q13438 8
Detoxification of reactive oxygen species 0.4611015100249571 0.8137040621898983 0.4158145064828265 1.0 0.8272824516222038 10 P07237 1
Striated muscle contraction 0.5302987398372876 0.7997903804883941 0.4238322573534017 1.0 0.8317265328843217 6 P08670 1
Metabolism of steroid hormones 0.505772717474073 0.7927257535235746 0.427937622316648 1.0 0.8339752556627344 7 O95772,P30536,Q14849 3
Diseases associated with glycosaminoglycan metabolism 0.5055573210811491 0.7916976324682697 0.4285370031301443 1.0 0.8339898306773114 7 Q8NCH0,Q93063 2
Ptk6 regulates proteins involved in rna processing 0.7404559187036501 0.7738978615562321 0.4389911942922486 1.0 0.8473131407640799 2 Q07666 1
Synaptic adhesion like molecules 0.4982816311970456 0.757055774770997 0.4490164481331922 1.0 0.8611117120365759 7 P41440,O95197 2
Epha mediated growth cone collapse 0.4906175897859497 0.7207646395615455 0.4710543346695435 1.0 0.8756141920176607 7 P35579,O75116,Q7Z406,P35580,Q13464 5
Creb phosphorylation 0.7223290304861271 0.7068037638625814 0.479688435238438 1.0 0.878509243916004 2 Q15418 1
Rrna modification in the mitochondrion 0.7070393663237938 0.6993522722116895 0.484331907235592 1.0 0.8805466545741281 3 Q9HC36 1
Synthesis of pc 0.4808061636445592 0.6746529102956764 0.4998963087916679 1.0 0.8961245535463869 7 Q9Y6K0,Q8NF37 2
Signaling by erbb4 0.4763301436593394 0.6537634005480336 0.5132642495117745 1.0 0.9085944866096548 7 P62993,P78536,Q92542 3
Sensory processing of sound by outer hair cells of the cochlea 0.4018393425421253 0.6381874519137681 0.5233516644533136 1.0 0.9229067524589724 14 O14936 1
Neurotransmitter clearance 0.6992584454820068 0.6240520849673801 0.5325933797627005 1.0 0.9264494717106728 2 P21964 1
Raf activation 0.4113680653552279 0.6123417109019742 0.5403116983136576 1.0 0.9318227453169444 12 Q16537 1
Selective autophagy 0.3430911327359526 0.6052196626274865 0.5450330527624567 1.0 0.9334819153259885 36 Q8N4H5,Q15388,P08670,Q9NS69 4
Pre notch expression and processing 0.4100844607207817 0.6049641011031452 0.545202849784094 1.0 0.9334819153259885 12 Q9UBV2 1
Signaling by hippo 0.4650715071507246 0.6016857946370336 0.54738330753871 1.0 0.9334819153259885 7 Q07157,Q4VCS5,O14641,Q13043,P62258,Q9UDY2 6
Rnd1 gtpase cycle 0.3879347277688663 0.595655095954515 0.5514056619105414 1.0 0.9334819153259885 15 P51648,Q9BXS4,Q8TAA9,O43396 4
Sema4d induced cell migration and growth cone collapse 0.4818252224253757 0.5846088302094471 0.5588107689014365 1.0 0.9347877316128428 6 Q7Z406,P35580,P35579,Q13464 4
Rhof gtpase cycle 0.3703796772284493 0.580923200951348 0.5612922148454684 1.0 0.9347877316128428 17 P42167 1
Rnd3 gtpase cycle 0.3610063353067914 0.5733593270567323 0.566401423433686 1.0 0.93638848440524 18 Q07065,O43396,P38159,Q8TAA9,Q9NYL9,Q9Y2I1 6
Slc transporter disorders 0.3393511394284693 0.5707440371356272 0.5681731629684981 1.0 0.93638848440524 35 P11166,Q9BTX1,P53985,Q8TEM1,Q7Z3B4,P35613,O00400 7
Integrin cell surface interactions 0.4579043703522084 0.568923702655273 0.5694079191159123 1.0 0.93638848440524 7 P06756,P35613 2
Rhobtb1 gtpase cycle 0.3564250837726478 0.5648789891442451 0.5721560756600894 1.0 0.9384958214261536 20 P08670,O43396,P38159,P62995,Q13464 5
Rhoc gtpase cycle 0.3376853633651701 0.5560441980548356 0.5781806406592187 1.0 0.9472750263823712 36 P49257,Q8TAA9,P42167,P41440,Q86VI3 5
Protein protein interactions at synapses 0.3730104395842499 0.546658753613956 0.5846131961597685 1.0 0.9517488587702008 16 P41440,O95197,O14936 3
Beta oxidation of lauroyl coa to decanoyl coa coa 0.5221911822981992 0.5405582246963849 0.5888121186204467 1.0 0.9520671382487866 4 P30084,P40939 2
Sulfur amino acid metabolism 0.398781980503514 0.5404465287656656 0.588889127251897 1.0 0.9520671382487866 12 Q9UBX3 1
Costimulation by the cd28 family 0.3782088790516047 0.5340447251972498 0.5933105907921199 1.0 0.9538731718635453 15 P62993,Q16537 2
Ripk1 mediated regulated necrosis 0.4036461199048859 0.533457882782286 0.5937166584274869 1.0 0.9538731718635453 11 P41440 1
Negative regulation of nmda receptor mediated neuronal transmission 0.4470013882864847 0.5197528157353114 0.603235869895999 1.0 0.9578830120959388 7 Q13555 1
Metabolism of steroids 0.3238561103696793 0.5167062008395695 0.6053612667863244 1.0 0.9578830120959388 54 Q15392,Q9HCL2,Q14849,P04062,P37268,Q15800,P30536,P48449,O95772,Q9H2C2,P38435,Q9H4L5,Q14739 13
Anchoring of the basal body to the plasma membrane 0.3321529104872936 0.5108541333603053 0.6094532002223227 1.0 0.9583923650817552 40 Q15154,O95684,Q9H6D7,Q15051,O75935,Q96CS2,Q6NUS6,O94927,Q9UPN4 9
Long term potentiation 0.4776936280928776 0.4925371207078194 0.6223396868800162 1.0 0.9604344127206385 5 Q13555 1
Ras activation upon ca2 influx through nmda receptor 0.4776936280928776 0.4925371207078194 0.6223396868800162 1.0 0.9604344127206385 5 Q13555 1
Unblocking of nmda receptors glutamate binding and activation 0.4776936280928776 0.4925371207078194 0.6223396868800162 1.0 0.9604344127206385 5 Q13555 1
Cation coupled chloride cotransporters 0.6550398242241093 0.4758032760246268 0.6342145357222384 1.0 0.9685731883489104 2 P55011 1
Binding and uptake of ligands by scavenger receptors 0.4342001272015384 0.4632015347571841 0.6432199162489485 1.0 0.9700731477524486 7 Q9Y4L1,Q8WTV0,P14625 3
Glycogen storage diseases 0.6354638341274073 0.4611210552248519 0.6447117564404117 1.0 0.9700731477524486 3 P10253 1
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation 0.5003945711141531 0.4601874345715621 0.6453816894053201 1.0 0.9700731477524486 4 P00374 1
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.3725525552231797 0.4597146948272832 0.645721020449574 1.0 0.9700731477524486 14 P05067,P09601 2
Cdc42 gtpase cycle 0.3263010632454365 0.4536584197718787 0.6500746987137864 1.0 0.9724058956795034 38 Q86VI3,P42167,Q8TAA9,Q9UQB8 4
Signaling by braf and raf1 fusions 0.3312421281952921 0.4414048821957206 0.6589199083805624 1.0 0.9766678522531046 24 P51797,Q9NRY5,Q13555 3
Role of second messengers in netrin 1 signaling 0.6407580335072728 0.4314252232962522 0.6661592129669056 1.0 0.9766678522531046 2 Q00169 1
Fatty acyl coa biosynthesis 0.3547447387408999 0.4284741554937093 0.6683059457610143 1.0 0.9766678522531046 16 Q9UKU0,Q9UMR5,P50897 3
Fceri mediated ca 2 mobilization 0.4914653783693431 0.4284373809933038 0.6683327142699222 1.0 0.9766678522531046 4 O43865 1
Chl1 interactions 0.4894201703764924 0.4212703997897303 0.6735576422483298 1.0 0.979404249667592 4 O14786,P05556,P11142 3
Class b 2 secretin family receptors 0.6360889865421531 0.4173377478835389 0.6764313817579806 1.0 0.9815569689979348 2 Q9UBI6 1
Glyoxylate metabolism and glycine degradation 0.3630198785101169 0.4032101913280426 0.6867936030232555 1.0 0.9896120693774212 14 P30038,Q9NR77 2
Dag and ip3 signaling 0.4017374682268084 0.4011483124964216 0.6883109327706722 1.0 0.989847297622832 8 Q13555 1
Ub specific processing proteases 0.2898440910294992 0.3979021856818153 0.6907022888502414 1.0 0.989847297622832 80 Q96RU2,P49721,P45880,P60900,Q15388,P28070,P28074,Q9UPT9,P28072,P21796 10
Cilium assembly 0.2828369748762818 0.3924165240212932 0.6947504787739129 1.0 0.989847297622832 74 A6NIH7,Q9Y366,O00471,Q15154,O95684,Q9H6D7,Q15051,Q96RK4,Q96CS2,O75935,O43924,Q6NUS6,O94927,Q92973,Q9UPN4 15
Fgfr1 mutant receptor activation 0.3770735595587359 0.3916201781610517 0.6953388764389918 1.0 0.989847297622832 11 O95684,O94905 2
Rho gtpases activate ktn1 0.4141914191419242 0.3778665443078157 0.7055297367916629 1.0 0.989847297622832 7 P63000,Q07866,P33176,Q9H0B6,Q86UP2,P84095 6
Signaling by fgfr1 in disease 0.3693448431834821 0.3773882649237121 0.7058850865211956 1.0 0.989847297622832 12 O95684,O94905 2
Sema4d in semaphorin signaling 0.3963738332377177 0.3771732038341462 0.7060448924916569 1.0 0.989847297622832 8 Q7Z406,P35580,P35579,Q13464 4
Interleukin 12 family signaling 0.3155704009306733 0.3703632965896436 0.7111118175293634 1.0 0.989847297622832 30 Q9UL46,P07355,P07237,P52597,O00170,P51809,O14979,P22626,P27824,P14174 10
Recruitment of mitotic centrosome proteins and complexes 0.316520398485513 0.3650267805022705 0.7150914155822434 1.0 0.9926736990693408 39 Q15154,O95684,Q9H6D7,Q96CW5,O75935,Q96CS2,O94927,Q9UPN4 8
Regulation of runx3 expression and activity 0.3159756299273838 0.359730666947593 0.7190485562957334 1.0 0.9937534368619686 38 P49721,P60900,P28070,P28074,P28072 5
Regulation of mecp2 expression and activity 0.3751465216748032 0.3592665777239609 0.7193956746623194 1.0 0.9937534368619686 10 Q13555 1
Global genome nucleotide excision repair gg ner 0.3118658529501415 0.3374959311109544 0.735743078916999 1.0 1.0 46 Q9H981,Q92905,P41440,Q9UGN5,Q7L5N1 5
Scavenging by class f receptors 0.4640619032122575 0.3359913626225013 0.7368773798695245 1.0 1.0 4 Q9Y4L1 1
Synthesis of pips at the er membrane 0.6072507552870026 0.3353190768269559 0.7373844046902625 1.0 1.0 2 Q9NTJ5 1
Regulation of hmox1 expression and activity 0.3090884375138844 0.3309758289641992 0.7406627432572896 1.0 1.0 50 P49721,P60900,Q8TCT9,P28070,P09601,P28074,P28072 7
G alpha i signalling events 0.3131476266153064 0.3185963664930251 0.7500326090965073 1.0 1.0 25 P05067,Q9NZJ7,P07602,Q13555,P22466,O43865 6
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.3194458297186911 0.3083383189539943 0.7578249111450888 1.0 1.0 21 Q9BT22,Q96AA3,Q86YN1,Q9UJ70 4
Met interacts with tns proteins 0.596814062070853 0.3078997477548823 0.7581586177368351 1.0 1.0 2 Q9NWH9 1
Copii mediated vesicle transport 0.3093970175611197 0.3038386243561918 0.7612508389735155 1.0 1.0 35 P49257,P49755,Q8NI22,Q9HCU5 4
Assembly and cell surface presentation of nmda receptors 0.3579789065253818 0.2946334734660477 0.7682738885277358 1.0 1.0 11 O14936,Q13555 2
Tysnd1 cleaves peroxisomal proteins 0.4039007719871155 0.2738615732094446 0.7841910031062431 1.0 1.0 6 Q2T9J0 1
Heme signaling 0.3864775397023493 0.2673564909628456 0.7891946956301734 1.0 1.0 7 P09601 1
Mitochondrial trna aminoacylation 0.3218628697868749 0.2611528256120562 0.7939746557175162 1.0 1.0 17 Q5JPH6,Q9BW92,Q9NSE4,Q5ST30,Q5JTZ9,Q5T160 6
Assembly of the hiv virion 0.5631868131868147 0.2609901930321297 0.7941000700637499 1.0 1.0 3 Q99816,Q9UK41 2
Degradation of axin 0.3048941281395854 0.26043222251772 0.7945303902659124 1.0 1.0 38 P49721,P60900,P28070,P28074,P28072 5
Cross presentation of soluble exogenous antigens endosomes 0.3048941281395854 0.26043222251772 0.7945303902659124 1.0 1.0 38 P49721,P60900,P28070,P28074,P28072 5
Transcriptional regulation by runx3 0.3033426436407434 0.2471298305099891 0.8048077481694602 1.0 1.0 42 P49721,P60900,P28070,P28074,P28072 5
Irs mediated signalling 0.4342112161045439 0.2453072517577068 0.8062185371766273 1.0 1.0 4 P62993 1
Plasma lipoprotein assembly remodeling and clearance 0.3091020474602491 0.2285044518527801 0.8192540955892436 1.0 1.0 20 Q6PIU2,Q8WTV0,P07237,P02654,P61916 5
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.3484892872760729 0.2033963307332473 0.838825267522824 1.0 1.0 9 Q13555,P07196 2
Notch3 activation and transmission of signal to the nucleus 0.5367116815651505 0.2012719592936381 0.840485927133696 1.0 1.0 3 Q92542 1
Regulation of ras by gaps 0.2975818874374105 0.1950230992469175 0.8453748642299765 1.0 1.0 39 P49721,P60900,P28070,P28074,P28072 5
Chondroitin sulfate dermatan sulfate metabolism 0.3627837702172727 0.1817168925638875 0.8558049083429871 1.0 1.0 7 Q8NCH0,Q9P2E5 2
Aurka activation by tpx2 0.2958822192117485 0.1800940765229227 0.857078712829495 1.0 1.0 39 O95684,Q9H6D7,O75935,Q96CS2,O94927 5
Myoclonic epilepsy of lafora 0.536391101345776 0.1755241670926267 0.860667782948568 1.0 1.0 2 P13807 1
Interleukin 12 signaling 0.2896148988017458 0.1713205954140296 0.8639716870678782 1.0 1.0 27 Q9UL46,P07355,P07237,P52597,O00170,P51809,O14979,P22626,P14174 9
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.3819668881455055 0.166524770072752 0.8677439916093743 1.0 1.0 5 P62993 1
Tp53 regulates metabolic genes 0.294274670339426 0.1651851383425245 0.8687982624585093 1.0 1.0 40 P13073,P31751,O43819,P20674,P54619,Q8N8Q8,P00403,O75880 8
Transcriptional regulation by mecp2 0.315098447817703 0.160405419780656 0.87256172053427 1.0 1.0 15 Q13555 1
Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain 0.5145604395604412 0.1576620767267917 0.874723085054359 1.0 1.0 3 Q92696,P53611 2
Asymmetric localization of pcp proteins 0.2930781097285707 0.1546662110008244 0.8770844691054835 1.0 1.0 40 P49721,P60900,P28070,P28074,P28072 5
Signaling by notch 0.2781990771507213 0.1543418216347807 0.8773402234619752 1.0 1.0 65 P78536,P49721,P60900,P28070,Q9UBV2,P28074,P28072 7
Negative regulation of the pi3k akt network 0.3093129229229764 0.1540722925697937 0.877552734720557 1.0 1.0 16 P62993,Q16537 2
Myogenesis 0.364861149298886 0.1464112606832373 0.8835967383630889 1.0 1.0 6 P19022,P35222,P35221,P60953,O60271 5
Degradation of beta catenin by the destruction complex 0.2891856179200286 0.1448755525578101 0.8848091290011979 1.0 1.0 52 P49721,P60900,P28070,P28074,P28072,Q16537 6
Flt3 signaling 0.3735514330368454 0.1440546889233031 0.8854572844340765 1.0 1.0 5 P62993 1
Degradation of dvl 0.2918636046166983 0.1440255743197026 0.8854802747885626 1.0 1.0 40 P49721,P60900,P28070,P28074,P28072 5
Inla mediated entry of listeria monocytogenes into host cells 0.5155177149134778 0.1407737799694916 0.8880486573144599 1.0 1.0 2 P35222 1
Rora activates gene expression 0.3871365868745312 0.127860857109992 0.8982590882248107 1.0 1.0 4 Q86X55,P50416 2
Scf skp2 mediated degradation of p27 p21 0.2893464199775684 0.1209709441119863 0.9037140493866214 1.0 1.0 42 P49721,P60900,P28070,P28074,P28072 5
Glycogen breakdown glycogenolysis 0.3429592959295998 0.1175523412965014 0.9064223691571688 1.0 1.0 7 P06737,Q96G03,P46020,P46976,P10253,P35573 6
Gaba synthesis release reuptake and degradation 0.4906593406593423 0.1173125868480744 0.9066123510413532 1.0 1.0 3 P80404,P11142 2
Platelet activation signaling and aggregation 0.2770502288979264 0.1143876301385726 0.9089305193512618 1.0 1.0 63 Q9NTK5,Q8NBX0,Q9Y6I9,P05067,P07602,Q9BWS9,O43852,Q08380,Q8NBM8,Q8NBF2,Q96JJ7,O94919 12
Synthesis of pips at the early endosome membrane 0.3767518549052003 0.1066050848375602 0.9151022844598526 1.0 1.0 4 Q96PE3,O00443,Q9BTU6 3
Platelet adhesion to exposed collagen 0.4891513320516243 0.1048765924342245 0.9164737330512508 1.0 1.0 2 P05556 1
Complement cascade 0.4831090359791217 0.0978600921654079 0.9220433896674568 1.0 1.0 2 P10909 1
Linoleic acid la metabolism 0.4778906893710484 0.0921487846445873 0.9265798287633104 1.0 1.0 2 O95864 1
Synthesis of udp n acetyl glucosamine 0.363609885950824 0.082207971131035 0.9344813348572758 1.0 1.0 4 Q9UJ70 1
Arms mediated activation 0.4645604395604414 0.0811699655018682 0.9353067847364424 1.0 1.0 3 P46108,Q9ULH0 2
Inositol phosphate metabolism 0.3392906241407933 0.0770048717892224 0.9386196693507436 1.0 1.0 6 Q96PE3,Q9NPH2,Q13572,P19174,Q9BW91 5
Negative regulation of met activity 0.3166437414030331 0.0729965470821535 0.9418088652113604 1.0 1.0 8 O14964,P62993,Q92783,P18031,P42566,Q9NWH9,P40818 7
Listeria monocytogenes entry into host cells 0.3166437414030307 0.0729965470821463 0.941808865211366 1.0 1.0 8 O60716,O14964,P62993,Q92783,P35222,Q9NWH9,P42566 7
Advanced glycosylation endproduct receptor signaling 0.3132178057832752 0.0713329024498766 0.9431328095497526 1.0 1.0 9 P14314 1
Stabilization of p53 0.2833714651396692 0.0694554536459379 0.9446270898212004 1.0 1.0 41 P49721,P60900,P28070,P28074,P28072 5
Wax and plasmalogen biosynthesis 0.3403762693496732 0.0674713000195899 0.9462065092124394 1.0 1.0 5 Q6IAN0,O15228 2
Metabolism of polyamines 0.2828540178034147 0.0663399493638789 0.9471071782673016 1.0 1.0 40 P49721,P60900,P28070,P28074,P28072 5
Auf1 hnrnp d0 binds and destabilizes mrna 0.2828021930942938 0.0636832846302933 0.9492224146599956 1.0 1.0 42 P49721,P60900,P28070,P28074,P28072 5
Killing mechanisms 0.4441087613292977 0.0624598780548741 0.9501966121983748 1.0 1.0 2 O14641 1
Sema4d mediated inhibition of cell attachment and migration 0.444108761329294 0.0624598780548716 0.9501966121983768 1.0 1.0 2 Q9NWH9 1
Signaling by notch1 pest domain mutants in cancer 0.3124903338265668 0.060544111956768 0.9517222840037638 1.0 1.0 8 P78536 1
Iron uptake and transport 0.2827173198340365 0.0597149383224627 0.9523826739065764 1.0 1.0 18 P30519 1
Intra golgi traffic 0.2818505381943339 0.056043311924118 0.9553073034334552 1.0 1.0 21 Q96JB2,O14653,O43752,O60476,Q9Y2V7,O95721,O95249,O00461 8
Runx1 regulates transcription of genes involved in differentiation of hscs 0.2817900063291261 0.0549383845758696 0.9561875515718046 1.0 1.0 42 P49721,P60900,P28070,P28074,P28072 5
Sensory processing of sound 0.2805305156021279 0.0460153560447489 0.9632980105204398 1.0 1.0 19 O14936 1
Uch proteinases 0.2800990484528011 0.0458868650579945 0.963400423315266 1.0 1.0 49 P49721,P60900,O15294,P28070,Q9H981,P28074,P28072 7
Mitochondrial translation 0.2674335795407605 0.0456145238765251 0.9636174928427016 1.0 1.0 66 Q8N5N7,Q9NYK5,Q13084,P82932,Q9BYD3,Q92552,Q8N983,Q9NQ50,Q92665,Q7Z7H8,P82933,Q9BRJ2,Q15070,O75616,Q96GC5,P82650,Q9Y291,Q96EY7,Q9Y3D3,Q9BYN8,Q96EL2,Q9H9J2,Q8TAE8 23
Negative regulation of notch4 signaling 0.2802617624707375 0.0417980397167123 0.9666596977284364 1.0 1.0 42 P49721,P60900,P28070,P28074,P28072 5
Activation of ppargc1a pgc 1alpha by phosphorylation 0.4202892012825864 0.0375387563025178 0.970055438850362 1.0 1.0 3 P54619 1
Rhobtb gtpase cycle 0.2740280230616104 0.0333963900152015 0.9733584884090988 1.0 1.0 30 P61201,P08670,O43396,P38159,P62995,Q9NYL9,Q13464 7
Traf3 dependent irf activation pathway 0.3754463059598927 0.032560983877784 0.9740246836753444 1.0 1.0 2 Q7Z434 1
Traf6 mediated irf7 activation 0.3754463059598927 0.032560983877784 0.9740246836753444 1.0 1.0 2 Q7Z434 1
G protein activation 0.3570447679208915 0.0291563389414606 0.9767399028932224 1.0 1.0 2 Q9UBI6 1
Ptk6 regulates cell cycle 0.32546003845097 0.0258307378226033 0.9793923447867288 1.0 1.0 2 P11802 1
Inlb mediated entry of listeria monocytogenes into host cell 0.3164696178168914 0.0255832815881324 0.9795897210663164 1.0 1.0 6 O14964,P62993,Q92783,P42566,Q9NWH9 5
Nr1h2 nr1h3 regulate gene expression linked to lipogenesis 0.2914034605877447 0.0243489572801136 0.9805742624285892 1.0 1.0 2 O00767 1
Signal regulatory protein family interactions 0.398508418408223 0.0232201577775308 0.9814746593605276 1.0 1.0 3 P62993 1
Bmal1 clock npas2 activates circadian gene expression 0.3199521175068542 0.020837245673189 0.983375486431572 1.0 1.0 4 Q86X55,Q9BZK7 2
Gastrin creb signalling pathway via pkc and mapk 0.3139055661736299 0.0205444530809402 0.9836090511184246 1.0 1.0 5 Q15418 1
G1 s dna damage checkpoints 0.2776426645983874 0.019461831690476 0.984472685170526 1.0 1.0 42 P49721,P60900,P28070,P28074,P28072 5
Egfr downregulation 0.2958172812327927 0.0165935386825424 0.9867608792343474 1.0 1.0 9 Q9UBC2,O14964,P62993,Q92783,P42566,P60953,Q99961,Q9Y6I3 8
Apoptotic cleavage of cellular proteins 0.2746718884560883 0.0126819821088495 0.9898815135062312 1.0 1.0 19 Q13464,P08670,P51572,P02545,P49354,P35611,Q16625 7
Signalling to ras 0.3645604395604415 0.0083426910220841 0.9933435728531224 1.0 1.0 3 P62993,P11233 2
Hedgehog on state 0.2762689301041072 0.0062585015944647 0.9950064708024972 1.0 1.0 44 P49721,P60900,P28070,P28074,P28072 5
Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.3574175824175845 0.0061554465787485 0.9950886952244882 1.0 1.0 3 O14734,P51659 2
Synthesis of ip2 ip and ins in the cytosol 0.3390109890109909 0.0017134928935526 0.9986328311442034 1.0 1.0 3 Q96PE3,Q9NPH2 2
Diseases of mismatch repair mmr 0.33791208791209 0.0014965793739336 0.9988059028692688 1.0 1.0 3 P20585,P43246 2