msigdb_reactome/result.tsv

Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
Nervous system development	0.45214732516749	5.037226267766401	4.723263202466038e-07	0.0006464058747729	0.0001179482153918	206	O15144,Q9NR77,P60866,P62081,P62280,Q99460,Q16850,P09496,P61353,P48556,Q92530,P49721,Q96P70,Q15370,P35579,P05387,O00487,P35241,P39019,P62899,P42766,P61927,P62829,P28070,P35580,P62495,O14786,Q7Z406,P46782,Q8N8S7,P15311,P61254,Q13177,O00231,P46783,P62917,P62277,O43242,Q04637,P26038,Q9Y490,P35998,P08865,Q9UQ16,P18077,Q15008,P51665,P62861,Q9UNM6,Q9Y3U8,Q13885,Q13200,P20618,P62993,P19174,Q9BZI7,P46779,Q99436,P62241,P46778,P07900,Q9UL46,P59998,Q15418,P11940,P83881,Q14997,Q01082,P50570,P08238,P04350,P62906,P17612,P55036,P11142,P26373,P28072,P27361,P28074,Q9HAU5,Q06323,P62847,P35268,P62269,P62910,P35080,P17980,O15145,P49720,P18124,P28066,P23396,P39023,P46776,Q13617,Q13813,P62750,Q00169,P62701,P62191,O75122,Q00610	102
Signaling by robo receptors	0.4569851450453717	4.451810925316552	8.514912646973016e-06	0.0115892858590144	0.0003760295294744	137	P60866,P62081,P62280,Q99460,P61353,P48556,Q92530,P49721,Q15370,P05387,O00487,P39019,P62899,P42766,P61927,P62829,P28070,P62495,O14786,P46782,Q8N8S7,P61254,Q13177,O00231,P46783,P62917,P62277,O43242,Q04637,P35998,P08865,P18077,Q15008,P51665,P62861,Q9UNM6,Q9Y3U8,Q13200,P20618,Q9BZI7,P46779,Q99436,P62241,P46778,Q9UL46,P11940,P83881,Q14997,P62906,P17612,P55036,P26373,P28072,P28074,Q9HAU5,Q06323,P62847,P35268,P62269,P62910,P35080,P17980,P49720,P18124,P28066,P23396,P39023,P46776,Q13617,P62750,O75832,P25787,P49207,P61586,P62701,P62191,O75122	77
Regulation of expression of slits and robos	0.463235322181426	4.259984355884613	2.0444121251461667e-05	0.0276002446091692	0.000636090954392	123	P46778,P49720,P61254,P18124,P60866,P62081,P62280,Q9UL46,P23396,P39023,Q99460,O00231,P46776,P11940,P46783,P62917,P62277,O43242,Q13617,P83881,Q04637,P62750,P61353,P48556,Q92530,P49721,Q14997,Q15370,P35998,P05387,O00487,P08865,P18077,P62906,P55036,P62701,Q15008,P51665,P39019,P62899,P26373,P28072,P28074,P62191,P62861,Q9HAU5,P42766,P61927,P62829,P28070,Q06323,Q9UNM6,Q9Y3U8,P62847,Q13200,P17980,P20618,P62495,Q9BZI7,P46782,P35268,P62269,P46779,Q99436,P62910,P62241	66
S phase	0.4885721777075025	4.176463219460753	2.9607659013830556e-05	0.0397229911366164	0.0007640252699507	94	P33991,P49720,Q9UQE7,P31751,P28066,Q9UJX3,Q9UL46,P27694,Q99460,O00231,P49642,P28340,Q7Z5K2,Q9Y2S7,P24941,Q29RF7,P33992,P33993,P11802,O43242,Q14566,Q14683,P51530,P48556,Q92530,P49721,P35251,Q14997,O75832,P35998,P25787,Q9BRT9,O00487,P49643,Q07864,P55036,Q15008,P51665,P35244,P49736,P28072,P28074,P30260,P62191,P25205,P56282,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9Y248,Q16763,P17980,Q99436,Q8N3U4	56
Apoptosis	0.5078887732662115	3.944171555082832	8.007631977635654e-05	0.1038333331273713	0.0015017052297785	82	P10412,P49720,Q13177,P31751,P49327,Q9UL46,P31946,Q99460,O00231,O43242,Q13813,P35611,P48556,P08670,Q92530,P09429,P49721,Q14997,P35998,Q14126,O00487,P55036,Q15008,P51665,P62258,P27348,P27361,P28072,P26583,P28074,P30419,P62191,Q07157,O00429,Q04917,P28070,Q06323,Q9UNM6,Q13200,P20618,P40763,Q9UJU6,P17980,Q99436,Q13546,P63104	46
Mitotic g1 phase and g1 s transition	0.5213092459219758	3.895443433189986	9.801923697527748e-05	0.1255803872051192	0.0017427056547942	75	P33991,P14635,P49720,P31751,P28066,P27694,Q9UL46,P06493,P31350,P49642,Q99460,O00231,P24941,P33992,P33993,P11802,Q14566,O43242,P48556,Q92530,P49721,O75832,P35998,P25787,P49643,O00487,Q07864,P55036,Q15008,P51665,Q13309,P04818,P35244,P49736,P28072,P28074,P62191,P25205,P56282,P28070,Q06323,Q9UNM6,P00374,Q99436,Q13200,P20618,P17980,Q13616,P30153	49
Abc family proteins mediated transport	0.5972309270623568	3.832988254323672	0.0001265960002974	0.1591322591318378	0.0020389402871429	48	P08183,P49720,P40855,P28066,Q9UL46,O75027,Q99460,O00231,Q8NE71,P20042,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P56589,P55036,Q15008,P51665,P28072,P28074,P62191,P05198,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	33
Dna replication pre initiation	0.5608238135950154	3.806838057548823	0.0001407548465881	0.1752763739635616	0.0022406207555719	61	P33991,P49720,P28066,P27694,Q9UL46,P49642,Q99460,O00231,P24941,P33992,P33993,Q14566,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,Q07864,P55036,Q15008,P51665,P35244,P49736,P28072,P28074,P62191,P25205,P56282,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	39
Programmed cell death	0.4719641248617419	3.7890685051524966	0.0001512132146139	0.1870019303371978	0.0023117061459772	90	P07900,P10412,P49720,Q13177,P63104,P31751,P49327,Q9UL46,P31946,Q99460,O00231,O43242,Q13813,P35611,P48556,P08670,Q92530,P09429,P49721,Q14997,P35998,Q14126,O00487,P55036,Q15008,P51665,P62258,P27348,P27361,P28072,P26583,P28074,P30419,P62191,Q07157,Q16543,O00429,Q04917,P28070,Q06323,Q9UNM6,Q13200,P20618,P40763,Q9UJU6,P17980,Q99436,Q13546,Q8WUM4	49
Eukaryotic translation initiation	0.446950125519956	3.78821211573215	0.0001517352794757	0.187582865955281	0.0023117061459772	102	P46778,P61254,P60866,P62081,P62280,Q9UI10,P23396,P39023,P46776,O75821,P11940,P46783,P62917,P62277,P20042,P83881,P55884,Q04637,P62750,P61353,Q14152,P55010,P60228,O60841,P05387,P08865,Q9Y262,P18077,P62906,P62701,P39019,P62899,P26373,P62861,Q15056,P42766,P61927,P23588,P05198,Q13144,P62829,Q9Y3U8,P62847,O75822,P35268,P62269,P46782,P62910,P46779,O15372,P62241	51
Auf1 hnrnp d0 binds and destabilizes mrna	0.609229671038893	3.784083666765685	0.0001542759226131	0.1904040893684205	0.0023209201984336	41	P49720,P28066,Q9UL46,O00231,Q99460,P11940,O43242,Q04637,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P11142,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	29
Cellular response to hypoxia	0.6165647902870546	3.7491623647483014	0.0001774261921734	0.2156641793914513	0.0026401788813632	39	P49720,P28066,Q9UL46,O00231,Q99460,O43242,Q13617,P48556,Q92530,P49721,Q14997,Q15370,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	28
Hedgehog off state	0.5821674686043525	3.715300035531724	0.0002029627189976	0.2426154506585491	0.0029559144926362	49	P49720,P48729,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P04350,P35998,O00487,P17612,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13885,P17980,Q13200,P20618,Q9Y496,Q99436	31
Synthesis of dna	0.4868861896289833	3.692721333901676	0.000221867097667	0.2619692261073206	0.0031972216495385	82	P33991,P49720,P28066,Q9UJX3,Q9UL46,P27694,Q99460,O00231,P49642,P28340,Q9Y2S7,P24941,P33992,P33993,O43242,Q14566,P51530,P48556,Q92530,P49721,P35251,Q14997,O75832,P35998,P25787,Q9BRT9,O00487,P49643,Q07864,P55036,Q15008,P51665,Q13309,P35244,P49736,P28072,P28074,P30260,P62191,P25205,P56282,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9Y248,P17980,Q99436,Q16763	50
Hedgehog on state	0.590463004167262	3.6727826295244914	0.0002399235612984	0.2799933016923986	0.0034214099522661	42	P49720,P48729,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P32121,P28070,Q06323,Q9UNM6,P17980,Q13200,P20618,Q9Y496,Q99436	29
Scf skp2 mediated degradation of p27 p21	0.593753565066477	3.6503364810429506	0.0002618969961374	0.3013350266071291	0.0036585406909402	41	P49720,P28066,Q9UL46,O00231,Q99460,P24941,P11802,O43242,P48556,Q92530,P49721,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	28
Cyclin a cdk2 associated events at s phase entry	0.5840773951188516	3.645548369790872	0.0002668222200421	0.3060312582997912	0.0036896931236131	44	P49720,P31751,P28066,Q9UL46,Q99460,O00231,P24941,P11802,O43242,P48556,Q92530,P49721,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	29
Degradation of dvl	0.6080497929855873	3.633644791454479	0.0002794455116681	0.3179241210689103	0.0038185173753301	38	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	26
Cross presentation of soluble exogenous antigens endosomes	0.6121843641840985	3.626515174477935	0.0002872719449713	0.3251951843774021	0.0038185173753301	37	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	26
Degradation of axin	0.6121843641840985	3.626515174477935	0.0002872719449713	0.3251951843774021	0.0038185173753301	37	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	26
Dna replication	0.4680718693336799	3.626169694220164	0.0002876563588425	0.3255503175403823	0.0038185173753301	87	P33991,P49720,P28066,Q9UJX3,Q9UL46,P27694,Q99460,O00231,P49642,P28340,Q9Y2S7,P24941,P33992,P33993,O43242,Q14566,P51530,P48556,Q92530,P49721,P35251,Q14997,O75832,P35998,P25787,Q9BRT9,O00487,P49643,Q07864,P55036,Q15008,P51665,Q13309,P35244,P49736,P28072,P28074,P30260,P62191,P25205,P56282,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9Y248,P17980,Q99436,Q16763	50
Degradation of gli1 by the proteasome	0.5939889154262906	3.603928170834662	0.0003134437133416	0.3489518703717992	0.0038751467560881	40	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P17612,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	27
Metabolism of polyamines	0.5989934120492831	3.600942148645061	0.0003170661284717	0.3521734951116655	0.0038755672310515	39	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436,P52788	27
Orc1 removal from chromatin	0.5650874352345081	3.5963731037796047	0.0003226848836896	0.3571390917611233	0.0039093416439928	51	P33991,P49720,P28066,Q9UL46,Q99460,O00231,P24941,P33992,P33993,Q14566,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P49736,P28072,P28074,P62191,P25205,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	34
Transcriptional regulation by runx2	0.5601911135434642	3.5924172046225578	0.0003276247652661	0.3614733031461218	0.0039179284118537	53	P14635,P49720,P31751,P28066,Q9UL46,P06493,Q99460,O00231,P11802,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,Q9UBN7,P27361,P28072,P28074,P62191,P04150,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	34
Signaling by notch4	0.5796681685982096	3.591232842190067	0.0003291174341586	0.3627772047533618	0.0039179284118537	43	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q99436,Q13200,P20618,Q9Y6A5,P17980,Q06330,P63104	29
The role of gtse1 in g2 m progression after g2 checkpoint	0.5660428700097089	3.5853043178610866	0.0003366853745121	0.3693472519831178	0.0039395066470694	50	P07900,P14635,P49720,P28066,Q9UL46,P06493,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P08238,P04350,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13885,Q13200,P20618,P17980,Q99436	33
Regulation of runx3 expression and activity	0.6106912928735668	3.575256087909006	0.0003498852444232	0.3806450312190346	0.0040592618611477	36	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	25
Negative regulation of notch4 signaling	0.5879299077108088	3.5515853207933095	0.0003829178221537	0.4080392160938093	0.0044051638531801	40	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9Y6A5,P17980,Q99436,P63104	28
Abc transporter disorders	0.5810579063438875	3.5392650670751498	0.0004012427397088	0.4227105788186974	0.004496457196463	41	P49720,P28066,Q9UL46,O95342,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	27
G1 s dna damage checkpoints	0.5863005673298413	3.5374625938876925	0.0004039914062563	0.4248796650241169	0.004496457196463	40	P49720,P28066,Q9UL46,O00231,Q99460,P24941,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	27
Runx1 regulates transcription of genes involved in differentiation of hscs	0.5850555856228595	3.5266578789696905	0.0004208401751801	0.4379988951761512	0.0045724619033465	40	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	26
Regulation of runx2 expression and activity	0.5699016424377373	3.517938276778208	0.000434913509216	0.4487275374602547	0.0046881621584002	44	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P04150,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	28
Tnfr2 non canonical nf kb pathway	0.5741272987947752	3.478106660218569	0.0005049689490614	0.4991642586301988	0.0053177114712706	41	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,Q8TBC4,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	28
Stabilization of p53	0.5842599447723378	3.474924519830683	0.000510997112106	0.5032825088091764	0.0053401148585734	39	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	26
Developmental biology	0.3656477266166825	3.4664974253981793	0.0005272867847281	0.5142426150650257	0.0054686030931273	250	O15144,Q9NR77,P60866,P62081,P62280,Q99460,Q16850,P09496,P61353,P48556,Q92530,P49721,Q96P70,Q15370,Q14126,P35579,P05387,O00487,P35241,P39019,P62899,P42766,P61927,P62829,P28070,P35580,P62495,O14786,Q7Z406,P40763,P46782,Q06330,Q8N8S7,P15311,P61254,Q13177,O00231,P46783,P62917,P62277,P11802,O43242,Q04637,P26038,Q9Y490,P35998,P08865,Q9UQ16,P18077,Q15008,P51665,P62861,Q9UNM6,Q9Y3U8,Q13885,Q13200,P20618,P62993,P19174,Q9BZI7,P46779,Q99436,P62241,P07900,O60271,P59998,Q15418,P83881,Q01082,P50570,P08238,P04350,P26373,P28072,P28074,Q9HAU5,P62847,Q9Y2W1,P35268,P35080,P17980,P23396,P39023,P46776,Q13617,Q13813,P62750,Q00169,P62701,P62191,O75122,Q00610	92
Switching of origins to a post replicative state	0.5288559341637677	3.428310887773775	0.0006073495144955	0.5646974974820891	0.0060250832271338	59	P33991,P49720,P28066,Q9UJX3,Q9UL46,Q99460,O00231,P24941,P33992,P33993,Q14566,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P49736,P28072,P28074,P30260,P62191,P25205,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436,Q16763	37
Tcr signaling	0.5543328130598574	3.405656348157795	0.0006600520696713	0.5950167739602107	0.0063826369082427	46	P49720,Q13177,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P19174,P41240,P17980,Q99436,Q8N8S7	30
Cdt1 association with the cdc6 orc origin complex	0.5639496690916032	3.3876145087143854	0.0007050328003295	0.6192187854911696	0.0066082789272757	41	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	26
Regulation of pten stability and activity	0.5561206519650387	3.3655820660076023	0.0007638234211089	0.6486856324175835	0.0069356572632041	42	P49720,P31751,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	27
Defective cftr causes cystic fibrosis	0.5666536259613444	3.365574724491537	0.0007638437481145	0.6486954160150338	0.0069356572632041	40	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	26
Transcriptional regulation by runx3	0.5607835406490966	3.3592968431404184	0.0007814108195631	0.6570496476076317	0.0069464377401428	41	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P25440,P48556,Q92530,P49721,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q06330,Q13200,P20618,P17980,Q99436	27
Antigen processing ubiquitination proteasome degradation	0.4520469989955023	3.354378748665634	0.0007954340522882	0.6635758422976483	0.0070254788231133	85	P49720,Q9UIQ6,P55786,Q14139,P28066,Q9UJX3,Q9UL46,Q99460,O00231,Q13867,O43242,Q13617,P48556,O94822,Q92530,Q9Y3I1,P49721,Q14997,Q9UII4,Q5T4S7,Q15370,O75832,Q93034,P35998,P22314,P25787,O00487,Q92990,P55036,Q15819,Q15008,P51665,O95714,Q13309,P61086,P28072,P28074,P30260,P62191,Q7Z6Z7,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9ULT8,O95376,P17980,Q99436,Q16763	50
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1	0.5427510451166159	3.3467720177442675	0.0008175842048647	0.6736322858854232	0.0071748254901274	49	P49720,P28066,Q9UJX3,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P30260,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436,Q16763	30
Asymmetric localization of pcp proteins	0.5735447900000565	3.341018968669272	0.0008347152002925	0.6812034964860041	0.0071869503723301	38	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	26
Interleukin 1 signaling	0.5457878598069396	3.311202002442492	0.0009289612337723	0.7198244750452407	0.007887967315484	45	P49720,P45985,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P09429,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	28
Regulation of hmox1 expression and activity	0.5440545016959731	3.3098622163511737	0.0009334190687424	0.7215307006989637	0.007887967315484	46	P49720,P28066,Q9UL46,O00231,Q99460,P09601,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	28
Hedgehog ligand biogenesis	0.5644751483538392	3.3031461231942396	0.0009560655455846	0.7300395483171794	0.0080297774963524	39	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	26
Mapk6 mapk4 signaling	0.5402898098705885	3.289981904870612	0.0010019382580312	0.7464872320693193	0.0083637407027124	47	P49720,Q13177,P28066,Q9UL46,P06493,O14980,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P17612,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q16181,Q13200,P20618,Q9HCE1,P17980,Q99436	32
Selenoamino acid metabolism	0.4329597531798583	3.2761670116775887	0.0010522631569402	0.7633816354482665	0.0086780015774172	90	Q9P2J5,P61254,P60866,P62081,P62280,P23396,P39023,P46776,P46783,P62917,P62277,P83881,P62750,P61353,P57772,P05387,P07814,P08865,P18077,P62701,P39019,P62899,P26373,P62861,P42766,P61927,Q16881,P62829,Q9Y3U8,P62847,P35268,P46782,P46779,P62241	34
Fceri mediated nf kb activation	0.5496333245716676	3.258933224230546	0.0011183198679725	0.7838616572550926	0.0090993116438136	41	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	26
Dectin 1 mediated noncanonical nf kb signaling	0.5443933835666012	3.258505115795488	0.001120008569527	0.7843613142986553	0.0090993116438136	42	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,Q8TBC4,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	28
Response of eif2ak4 gcn2 to amino acid deficiency	0.462248282257396	3.256752182537719	0.0011269477486195	0.786402407754635	0.0090993116438136	77	P46778,P61254,P60866,P62081,P62280,P23396,P39023,P46776,P46783,P62917,P62277,P20042,P83881,P62750,P61353,Q92616,P08243,P05387,P08865,P18077,P62906,P62701,P39019,P62899,P26373,P62861,P42766,P61927,P05198,P62829,Q9Y3U8,P62847,P35268,P62269,P46782,P62910,P46779,P62241	38
Signaling by hedgehog	0.5234779630853399	3.256000271414963	0.0011299364349512	0.7872755426205028	0.0090993116438136	54	P49720,P48729,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P04350,P35998,O00487,P17612,P55036,Q15008,P51665,P28072,P28074,P62191,P32121,P28070,Q06323,Q9UNM6,Q13885,P17980,Q13200,P20618,Q9Y496,Q99436	32
Regulation of ras by gaps	0.5531980191969916	3.2461291910573915	0.0011698573806022	0.7986020079916477	0.0091516271659686	40	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	26
Clec7a dectin 1 signaling	0.5325521580670557	3.161170357260388	0.001571365666888	0.8838521733160203	0.0116913021628793	43	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,Q8TBC4,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	28
Apc c mediated degradation of cell cycle proteins	0.5081283100547581	3.144680987217607	0.0016626802956449	0.8975216507029015	0.0123038341877728	56	P14635,P49720,P28066,Q9UJX3,Q9UL46,P06493,Q99460,O00231,P24941,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P30260,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436,Q16763	33
G2 m checkpoints	0.4310341725600453	3.083046112598596	0.0020489340315221	0.9396665281707955	0.01468581512646	85	P33991,P14635,P49720,P28066,P27694,Q9UL46,P06493,P31946,Q99460,O00231,P24941,P33992,P33993,O43242,Q14566,P51530,P48556,Q92530,P49721,Q14997,O75832,P35998,O60921,O00487,P55036,Q15819,Q15008,P51665,O95714,P62258,P35244,P49736,P27348,P28072,P28074,P62191,P25205,Q04917,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436,P63104	46
Mapk family signaling cascades	0.4258563290117457	3.077710908273942	0.0020859716937589	0.942655471590906	0.0147963484391499	87	P46940,P49720,Q13177,P62140,P30086,P28066,Q9UL46,P06493,P31946,Q99460,O00231,Q99956,O43242,Q13813,P48556,Q92530,P49721,Q14997,Q96P70,Q9Y490,Q01082,P35998,Q9Y4G8,O00487,P17612,P55036,Q15008,P51665,O60725,P27361,P28072,P28074,P18206,P32121,P62191,P28070,Q06323,Q9UNM6,Q99436,Q13200,Q16181,P20618,Q9HCE1,P62993,P41240,P17980,Q14738	47
Nonsense mediated decay nmd	0.4272645191451343	3.064487851478045	0.0021804302977102	0.9496253959073842	0.0152467873277162	86	P46778,P61254,P60866,P62081,P62280,P23396,P39023,P46776,P11940,P46783,P62917,P62277,P83881,Q04637,P62750,P61353,Q8ND04,Q92900,P05387,P08865,P18077,P62906,P62701,P39019,P62899,P26373,P62861,Q9HAU5,P42766,P61927,P62829,Q9Y3U8,P62847,P62495,Q9BZI7,P46782,P35268,P62269,P46779,P62910,P62241	41
Fc epsilon receptor fceri signaling	0.507854026218799	3.025630976308902	0.0024811491742289	0.9666572210709952	0.016983466097597	50	P49720,Q13177,P45985,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P27361,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P62993,P19174,P17980,Q99436	31
Pcp ce pathway	0.5017012556331696	2.964698010209623	0.0030298018958581	0.984300007126043	0.0201349456088822	50	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P09496,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P32121,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436,Q00610	30
Eukaryotic translation elongation	0.4341231611202976	2.9348754249349835	0.0033368162336522	0.9897013234075988	0.0218569446118177	78	P46778,P61254,P26641,P60866,P62081,P62280,P23396,P39023,P46776,P46783,P62917,P62277,P83881,P62750,P61353,P05387,P08865,P18077,P62906,P62701,P39019,P62899,P26373,P62861,P13639,P42766,P61927,P62829,Q9Y3U8,P62847,P35268,P62269,P46782,P62910,P46779,P62241	36
Recycling pathway of l1	0.6464937729909821	2.9189505770663486	0.0035121190172748	0.9919053671651428	0.0228028749221128	21	Q9UQ16,P50570,P15311,P35241,P26038,Q15418,P04350,Q00610	8
Adaptive immune system	0.3386972452216987	2.918735672450734	0.0035145409850736	0.9919322561957852	0.0228028749221128	172	Q99460,P09496,P48556,Q92530,P49721,Q15370,O00487,Q15819,Q9H0B6,P28070,Q14738,Q16763,Q8N8S7,P55786,Q13177,Q14139,O00231,P52732,O43242,Q9UII4,Q15436,P35998,O43237,Q9UQ16,Q15008,P51665,P42025,Q14203,Q7Z6Z7,Q9BXS5,Q9UNM6,Q13885,Q13200,P20618,P62993,P19174,P04439,O95376,Q9Y496,Q99436,Q9UIQ6,Q9Y6G9,P42345,Q9UJX3,Q9UL46,O94979,O75935,Q14997,Q13409,P50570,Q93034,P04350,Q9NZ32,Q92990,P17612,P55036,Q14204,O95714,P28072,P28074,P30260,Q13561,Q06323,P41240,Q9ULT8,P17980,P49720,P61163,P31751,P28066,P31946,Q13867,Q13617,O94822,Q9Y3I1,P09429,Q5T4S7,O75832,P22314,P61086,P62191,P78310,P33176,Q9UJW0,Q00610,P63104	86
C type lectin receptors clrs	0.4999743998646337	2.9022646458626276	0.0037047542063921	0.9937877161382972	0.023811307551882	47	P49720,Q13177,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P17612,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	29
Degradation of beta catenin by the destruction complex	0.4949250403685802	2.8815487991184385	0.0039572595182078	0.9956091649222748	0.0250809642612337	49	P49720,P48729,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,Q13363,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q99436,Q13200,P20618,Q14738,P17980,Q13616	31
Cellular response to starvation	0.4060382790849426	2.875562840367588	0.0040330785635656	0.9960437096277488	0.0254437076199139	89	Q15382,P61254,P42345,P60866,P62081,P62280,P23396,P39023,P46776,P46783,P62917,P62277,P83881,P62750,P61353,Q92616,P08243,P05387,P08865,P18077,P62701,P39019,P62899,P26373,P62861,P42766,P61927,P05198,P62829,Q9Y3U8,P62847,P35268,P46782,P46779,P62241	35
Srp dependent cotranslational protein targeting to membrane	0.3978597886358201	2.8300929136475155	0.0046534488017844	0.9983140736754154	0.0290653267180327	91	P46778,P43307,P61254,P60866,P62081,P62280,P23396,P39023,P46776,P09132,P46783,P62917,P62277,O76094,Q15629,P83881,P62750,P61353,P05387,P08865,P18077,P62906,P62701,P37108,P39019,P62899,P26373,P62861,P61011,P42766,P61927,P62829,Q9Y3U8,P62847,P35268,P62269,P46782,P62910,P46779,P51571,P62241	41
Copi mediated anterograde transport	0.4920079372468421	2.82396573744028	0.0047433455214838	0.9985101646713528	0.0292506307158168	47	Q8N6T3,P62820,Q9Y6G9,P61163,Q9Y678,P53621,Q13813,O75935,P48444,Q92538,Q13409,Q01082,Q15363,P04350,Q9NZ32,O43237,P24390,Q14204,P84085,P18085,Q14203,P61923,O60763,O15498,Q13885,Q9BVK6,Q9UJW0	27
Diseases of signal transduction by growth factor receptors and second messengers	0.3538716485041078	2.797442026250027	0.0051509010173698	0.9991496028673276	0.0310642444615827	140	P46940,P07900,P62140,P48729,P26641,P42345,P31946,Q99460,O00231,Q99956,O43242,O94979,P48556,Q92530,P26038,P49721,O15164,Q9Y490,Q01082,P35998,P35579,O00487,Q9HC35,Q15008,P51665,Q9UBN7,Q9NRY5,Q14203,P28072,P18206,P28074,P62191,Q16543,Q16630,P33176,P28070,Q9UNM6,P12270,Q99436,Q13200,O00203,P62993,P19174,P41240,Q14738,P40763,P17980,Q06330,Q00610	49
Interleukin 1 family signaling	0.4801257471517706	2.7483317667783416	0.0059899365240321	0.9997320957787974	0.0354988013047618	50	P49720,P45985,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P09429,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,Q9H3S7,P28070,Q06323,Q9UNM6,Q13200,P20618,P40763,P17980,Q99436	30
Vesicle mediated transport	0.3350758949370614	2.725657124321549	0.006417362409107	0.9998513148792368	0.0371710076081137	214	O00443,O15144,Q8WTV0,Q8IUR0,P20645,P09496,P48444,P49257,Q92538,P35579,P20339,P24390,Q16706,Q4KMP7,Q14108,Q9H0B6,P61923,O43617,O00203,P61201,Q99627,P52732,Q9NZZ3,Q15363,Q15436,O43237,Q9UQ16,Q8TD16,P84085,P62258,P60520,Q14203,Q8IYI6,Q92905,Q9BXS5,O60763,Q13885,P62993,P02786,Q9Y496,Q86X10,P07900,Q9UBW8,Q86SZ2,Q9UIQ6,Q9Y6G9,Q9BT78,Q9Y678,P59998,Q96A65,P31150,O94979,P53621,O60749,O75935,Q14671,Q14247,Q8TBA6,Q13409,Q01082,P50570,P04350,Q9NZ32,Q9P2W9,Q9UID3,Q14204,P11142,P18085,P27348,P32121,Q13561,Q12907,O15498,Q8N6T3,P62820,P61163,P31946,Q13813,Q9UJY4,Q07157,P33176,Q14C86,Q9BVK6,Q9UJW0,Q9UPT5,Q9Y4L1,Q00610,P63104	88
Fcgamma receptor fcgr dependent phagocytosis	0.5832567281022616	2.724750468452417	0.0064350100826318	0.999854886693322	0.0371710076081137	25	P07900,Q9NZQ3,P62993,P19174,Q9UQB8,P59998,Q96JJ3,P08238,P35579	9
L1cam interactions	0.5106865835763328	2.7203780320898434	0.0065207322418698	0.9998710536961825	0.0375079094080667	36	Q9UQ16,P09496,P15311,Q13813,P50570,P35241,P26038,O14786,Q01082,Q15418,P04350,Q00610	12
Mitotic g2 g2 m phases	0.4070254282733095	2.710777205867801	0.0067125712776454	0.9999010099700634	0.0382896253295693	83	P07900,Q9BSJ2,P14635,P49720,P62140,P61163,P28066,Q9UL46,P06493,Q99460,O00231,Q9H6D7,P24941,O43242,O75935,P48556,Q92530,P49721,Q14997,Q13409,P08238,P04350,P35998,O00487,P17612,P55036,Q15008,P51665,Q14008,Q14204,P62258,Q14203,P28072,P28074,P62191,Q15154,Q13561,P28070,Q06323,Q9UNM6,Q96CW5,Q13885,O94927,Q13200,P20618,P17980,Q99436	47
Selective autophagy	0.5636548345069892	2.6971845933561305	0.0069928494571001	0.9999327329327964	0.0395587227552481	27	P07900,P21796,Q9NS69,Q9Y6G9,Q8N4H5,Q9UBN7,Q13409,P04350,O43237	9
Regulation of mrna stability by proteins that bind au rich elements	0.450923837218897	2.675511467923103	0.0074615320433162	0.9999647532478736	0.0416932137440813	62	P49720,P28066,Q9UL46,O14980,P31946,Q99460,O00231,P11940,Q01105,Q92973,O43242,Q04637,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,Q9Y2L1,P51665,P11142,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P39687,P17980,Q99436,P63104	36
Clathrin mediated endocytosis	0.4752922928639443	2.670872865134809	0.0075654295036484	0.9999694592765388	0.0421019227255884	48	O00443,O15144,Q8N6T3,Q9UBW8,Q99627,P42566,Q9BT78,P59998,Q92747,P20645,P09496,Q14247,P50570,P20339,Q9UQ16,Q14108,P11142,P32121,Q92905,Q14C86,P62993,P61201,P02786,O15145,Q00610	25
Signaling by the b cell receptor bcr	0.4759811322899783	2.6409744864275244	0.008266794451244	0.999988397380591	0.0453758477328726	45	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P62993,P17980,Q99436	27
Uch proteinases	0.4747453249210862	2.6401754125865047	0.0082863125881798	0.9999887058199142	0.0453758477328726	46	P49720,Q9Y4E8,P28066,Q9UL46,Q99460,O00231,Q99496,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q16186,Q9UNM6,Q06323,Q13200,P20618,P17980,Q99436	29
Transport of bile salts and organic acids metal ions and amine compounds	0.851448040885869	2.6371033765136564	0.0083617345045903	0.9999898226133777	0.0454254545110482	2	P53985	1
Proton coupled monocarboxylate transport	0.851448040885869	2.6371033765136564	0.0083617345045903	0.9999898226133777	0.0454254545110482	2	P53985	1
Er to golgi anterograde transport	0.4322916390858352	2.6253110237742576	0.0086569849103741	0.9999932299974104	0.0462945794621179	68	Q8N6T3,Q86SZ2,P62820,Q9Y6G9,P61163,Q9Y678,Q8IUR0,O94979,Q13813,P53621,O75935,P48444,P49257,Q92538,Q13409,Q01082,Q15363,Q15436,P04350,Q9NZ32,O43237,P24390,Q14204,P84085,P18085,Q14203,Q13561,P61923,O60763,O15498,O43617,Q13885,Q9BVK6,Q9UJW0	34
Transport of small molecules	0.3429992473318159	2.621969931587085	0.0087423143683544	0.999993982569962	0.0463884820553383	141	P08183,Q8WTV0,P40855,Q9Y6M7,O00231,P35610,Q8NE71,P53985,Q86VP6,Q70HW3,P09601,O43242,P30519,P35611,Q10713,P49721,O15118,Q9H4A3,P56589,Q15008,P51665,P28072,P28074,P45880,P21796,P28070,Q99623,Q99436	28
Role of second messengers in netrin 1 signaling	0.8463373083475283	2.613470513709421	0.0089627817238469	0.9999955622623214	0.0471924929997938	2	P19174	1
Autophagy	0.4789423659253033	2.5989462622925332	0.0093510410649608	0.9999974046911057	0.048675190942705	41	P07900,Q15382,P21796,Q9NS69,Q9Y6G9,P42345,Q9UBN7,P04350,Q13409,Q9NT62,P08238,Q8N4H5,O43237	13
Downstream signaling events of b cell receptor bcr	0.4676002636446122	2.54734084594947	0.0108547354014487	0.9999996756272748	0.0550375287577161	44	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P17980,Q99436	26
Synthesis of pips at the late endosome membrane	0.8258943781942255	2.5183202590677687	0.0117916050017676	0.9999999113558956	0.0584880697370288	2	Q13614	1
Regulation by c flip	0.8207836456558761	2.4943778639478995	0.0126178141992003	0.999999971792892	0.0614725538743961	2	Q13546	1
Caspase activation via death receptors in the presence of ligand	0.8207836456558761	2.4943778639478995	0.0126178141992003	0.999999971792892	0.0614725538743961	2	Q13546	1
Signaling by interleukins	0.3568260280210941	2.473385422538847	0.0133839713280345	0.9999999902536878	0.064744370134556	107	P14174,P07900,Q13177,P45985,Q13126,Q9UL46,Q99460,O00231,Q15418,P09601,O43242,P48556,P08670,Q92530,P26038,P49721,P09429,Q14997,P35998,O00487,Q00169,P17612,P55036,Q15008,P51665,P78417,P11142,P27361,P28072,P28074,P62191,O00170,Q9H3S7,P28070,Q9UNM6,Q99436,Q13200,P20618,P62993,P17987,P40763,P17980,Q14738,P40222,P63104	45
Tcf dependent signaling in response to wnt	0.4363919116077881	2.4676395180489665	0.013600720837446	0.9999999927854448	0.0653311818472406	60	P49720,P31751,P48729,P28066,Q9UL46,O14980,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,Q14738,P17980,Q99436,P63104	32
Membrane trafficking	0.3225393002837887	2.4663825967479864	0.0136485462815603	0.9999999932487804	0.0653316778302659	207	O00443,O15144,Q8IUR0,P20645,P09496,P48444,P49257,Q92538,P35579,P20339,P24390,Q16706,Q4KMP7,Q14108,Q9H0B6,P61923,O43617,O00203,P61201,Q99627,P52732,Q9NZZ3,Q15363,Q15436,O43237,Q9UQ16,Q8TD16,P84085,P62258,P60520,Q14203,Q8IYI6,Q92905,Q9BXS5,O60763,Q13885,P62993,P02786,Q9Y496,Q86X10,Q9UBW8,Q86SZ2,Q9UIQ6,Q9Y6G9,Q9BT78,Q9Y678,P59998,Q96A65,P31150,O94979,P53621,O60749,O75935,Q14671,Q14247,Q8TBA6,Q13409,Q01082,P50570,P04350,Q9NZ32,Q9P2W9,Q9UID3,Q14204,P11142,P18085,P27348,P32121,Q13561,Q12907,O15498,Q8N6T3,P62820,P61163,P31946,Q13813,Q9UJY4,Q07157,P33176,Q14C86,Q9BVK6,Q9UJW0,Q9UPT5,Q00610,P63104	85
Sensory processing of sound by outer hair cells of the cochlea	0.7195051591407513	2.449993722816047	0.0142858705179031	0.9999999972132744	0.0674391611689982	12	P15311,P35241,P26038,Q01082,P35579	5
Separation of sister chromatids	0.3554445488527923	2.430136953938026	0.0150931184377898	0.9999999990921996	0.070529193840572	97	Q8N3U4,P49720,Q9UQE7,Q9Y6G9,Q9P258,P28066,Q9UJX3,Q9UL46,O14980,Q99460,O00231,Q7Z5K2,Q29RF7,O43242,Q14683,P48556,Q92530,P49721,Q14997,Q13409,O75832,Q2NKX8,P04350,P35998,O43237,O00487,P55036,Q15008,P51665,Q14008,Q14204,P28072,P28074,P30260,P62191,O75122,P28070,Q06323,Q9UNM6,Q13885,Q99436,Q13200,P17980,P20618,Q9Y266,Q14738,Q16763	47
Semaphorin interactions	0.5725465204888271	2.420578118138864	0.0154958494463386	0.9999999994814056	0.0719112470916528	21	P07900,Q13177,P35580,O14786,Q7Z406,P35579	6
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s	0.4438053448866514	2.388390414669563	0.0169223542313941	0.9999999999287597	0.0759564030910771	51	P60866,P62081,P62280,P23396,O75821,P11940,P46783,P20042,P62277,Q04637,Q14152,P60228,Q9Y262,P08865,P62701,P39019,P62861,Q15056,P05198,P62847,O75822,P46782,P23588,P62241	24
Aggrephagy	0.6623749831207194	2.3849477569857065	0.0170815469187146	0.9999999999429257	0.0761714584095126	14	P07900,Q14204,Q9Y6G9,Q9UBN7,Q13409,P04350,O43237	7
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand	0.4977391332044148	2.370451572180745	0.0177663712267324	0.9999999999780184	0.0782063093549732	30	P07900,Q9Y6G9,P61163,O75935,O60884,Q13409,P31948,P08238,P04350,Q9NZ32,O43237,Q14204,P0DMV9,P11142,Q14203,P04150,Q13885,Q02790,Q9UJW0,P31689	20
Arms mediated activation	0.7942078364565566	2.3688805259569357	0.017842015942818	0.999999999980218	0.0782875635439678	2	P31946	1
Transport to the golgi and subsequent modification	0.4016993621814965	2.317796175494292	0.0204604010644728	0.9999999999994882	0.0878065487688507	70	Q8N6T3,Q86SZ2,P62820,Q9Y6G9,P61163,Q9Y678,Q8IUR0,O94979,Q13813,P53621,O75935,P48444,P49257,Q92538,Q13409,Q01082,Q15363,Q15436,P04350,Q9NZ32,O43237,P24390,Q16706,Q14204,P84085,P18085,Q14203,Q13561,P61923,O60763,O15498,O43617,Q13885,Q9BVK6,Q9UJW0	35
Signaling by notch	0.424036308982019	2.289832767125457	0.0220310128815346	0.9999999999999432	0.0936354342659963	58	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P48556,Q92530,P49721,Q15363,O75832,P35998,P67809,O00487,P55036,Q15008,P51665,Q9UBN7,P28072,P28074,P62191,P32121,P28070,Q06323,Q9UNM6,Q06330,Q13200,P20618,Q9HCE1,P17980,Q99436,P63104	32
Egr2 and sox10 mediated initiation of schwann cell myelination	0.8776991867273174	2.2546205550930805	0.0241571561158064	0.9999999999999972	0.1008266668370094	5	Q9NR77	1
Parasite infection	0.5683877604741446	2.251790307199138	0.0243355265060578	0.9999999999999978	0.1012624188048425	19	Q9NZQ3,P62993,Q9UQB8,P59998,Q96JJ3,P35579	6
Grb2 sos provides linkage to mapk signaling for integrins	0.7632027257240304	2.220370384058135	0.0263936357136813	1.0	0.1088339978675596	2	P62993	1
Apoptotic execution phase	0.5000223953941548	2.1998891616276577	0.0278147598781033	1.0	0.1140072044105493	27	O00429,Q13813,Q13177,P35611,P08670,P09429,P26583,Q9UJU6,Q07157	9
Intra golgi and retrograde golgi to er traffic	0.3793512685268978	2.1954530505714382	0.028131115202348	1.0	0.114959691677655	76	Q8N6T3,P62820,Q9Y6G9,P61163,Q9Y678,P20645,P52732,P53621,O75935,P48444,Q8TBA6,Q92538,Q13409,Q15363,P04350,Q9NZ32,Q9P2W9,Q9UID3,O43237,P24390,Q8TD16,Q16706,Q14204,P84085,P18085,Q14203,Q9H0B6,P61923,P33176,O15498,Q13885,Q9BVK6,Q9UJW0,Q9Y496	34
Rho gtpase effectors	0.3384855291833409	2.1732174561515905	0.0297639545723296	1.0	0.1194922399106136	103	O15144,O60610,P46940,Q13177,Q9Y6G9,P62140,Q9NZQ3,Q9UQB8,P31946,P59998,Q13576,Q86VI3,Q13409,Q2NKX8,P04350,O43237,P35579,Q13526,Q14204,Q9H0B6,Q86UP2,P33176,O75122,O43663,P62993,P35580,P35080,Q7Z406,Q9Y266,P63104	30
M phase	0.2999028973694112	2.1270652493191218	0.0334146621387252	1.0	0.1295883072745463	172	P07900,Q9BSJ2,P62820,Q9UQE7,Q9Y6G9,P37198,P61163,P06493,Q99460,Q99986,O00231,Q9BTX1,Q01105,Q9H6D7,Q92973,Q29RF7,Q15021,O43242,O95347,O75935,P48556,Q14739,Q92530,P49721,Q13409,Q2NKX8,P04350,O43237,Q86XL3,O00487,Q9HC35,Q15008,P51665,Q14204,P50402,Q14203,P28072,P28074,P62191,Q9NTJ3,O60763,Q8N1F7,P28070,O75122,Q96CW5,P12270,P17980,Q9Y266,Q99436,Q16763	50
Cargo recognition for clathrin mediated endocytosis	0.483711000089506	2.1244916424918485	0.0336290541669448	1.0	0.1300513422444844	28	Q9UBW8,Q99627,P09496,P42566,Q9BT78,Q14108,P62993,P61201,P02786,P32121,P20645,Q92905,Q00610	13
Condensation of prometaphase chromosomes	0.6948291924023877	2.112528750946136	0.0346411226169371	1.0	0.1335878784861606	10	Q9NTJ3,P06493,O95347	3
Metabolism of porphyrins	0.7798349353271318	2.1077012496416696	0.0350568391542056	1.0	0.1344336493056233	7	P30519,P09601,P22830	3
Condensation of prophase chromosomes	0.7075772844947295	2.083659718799526	0.0371911307170995	1.0	0.1399305810774159	9	Q9NTJ3,Q01105,O95347	3
Sumo is conjugated to e1 uba2 sae1	0.7349233390119212	2.082992646187692	0.0372518938732708	1.0	0.1399305810774159	2	Q9UBT2	1
Sumo is transferred from e1 to e2 ube2i ubc9	0.7349233390119212	2.082992646187692	0.0372518938732708	1.0	0.1399305810774159	2	Q9UBT2	1
Processing and activation of sumo	0.7349233390119212	2.082992646187692	0.0372518938732708	1.0	0.1399305810774159	2	Q9UBT2	1
Infectious disease	0.2775740811515906	2.081258832637898	0.0374102210915516	1.0	0.1399305810774159	330	O15144,P23193,P45985,P48729,P60866,P62081,Q9UQB8,P62280,Q99460,Q99720,P09601,P09496,P61353,P48556,Q92530,P49721,Q8WX92,Q15370,P35579,P05387,P20339,O00487,P62826,Q16706,Q4LE39,P39019,P62899,P42766,P61927,Q14241,Q16881,P28070,P62829,P12270,P18615,P46782,Q8WUM4,P61254,Q13177,Q9NZQ3,O60942,O00231,P18074,P46783,Q9BTX1,P62917,P62277,O43242,P49917,P50750,Q9NZZ3,P35998,O43237,P08865,P18077,P19447,Q15008,P51665,P62861,P04150,Q9BXS5,Q9UNM6,Q9Y3U8,Q13885,Q13200,Q13426,P20618,P62993,P19174,P12956,P04439,P46779,Q99436,P62241,P46778,P07900,Q9Y6G9,P59998,P83881,Q13409,P08238,P04350,Q14204,P26373,P28072,P28074,Q8N1F7,P62847,Q9Y5B9,P35268,P17980,P43487,P37198,P23396,P39023,P46776,Q96JJ3,P62750,P62701,P62191,P23246,Q14839,Q02790,Q13546,Q00610	105
Cell cycle checkpoints	0.3199674492930389	2.0792124107899945	0.0375978314431353	1.0	0.1402164188413779	133	P33991,P14635,P49720,Q9Y6G9,Q9P258,P28066,Q9UJX3,Q9UL46,P06493,P27694,P31946,Q99460,O00231,P24941,P33992,P33993,O43242,Q14566,P51530,P48556,Q92530,P49721,Q14997,Q13409,Q2NKX8,P35998,O60921,O43237,O00487,P55036,Q15819,Q15008,P51665,Q14008,Q14204,O95714,P62258,P35244,P49736,P27348,P28072,P28074,P30260,P62191,P25205,O75122,Q04917,P28070,Q06323,Q9UNM6,P17980,Q99436,Q13200,P20618,Q9Y266,Q14738,Q16763,P63104	58
Sensory processing of sound	0.5662954356203989	2.0781941098670016	0.0376914843927151	1.0	0.1402164188413779	17	P15311,P35241,P26038,Q01082,P35579	5
Metabolism of cofactors	0.8320704471741579	2.068059337642516	0.038634443709411	1.0	0.1427480792337068	5	P00374,P07900	2
Retrograde neurotrophin signalling	0.7039682389990476	2.0659584126515056	0.0388324065625897	1.0	0.1427480792337068	9	P50570,Q9UQ16,Q00610	3
Class i mhc mediated antigen processing presentation	0.3306031497439318	2.0521180450457472	0.0401581916477826	1.0	0.1466041716421719	105	P49720,Q9UIQ6,P55786,Q14139,P28066,Q9UJX3,Q9UL46,Q99460,O00231,Q13867,O43242,O94979,Q13617,P48556,O94822,Q92530,Q9Y3I1,P49721,P09429,Q14997,Q9UII4,Q5T4S7,Q15370,Q15436,Q93034,O75832,P35998,P22314,P25787,O00487,Q92990,P55036,Q15819,Q15008,P51665,O95714,Q13309,P61086,P28072,P28074,P30260,P62191,Q7Z6Z7,Q8TBC4,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9ULT8,P04439,O95376,P17980,Q99436,Q16763	55
Ptk6 regulates cell cycle	0.728109028960841	2.0496234827767235	0.0404011870647691	1.0	0.1470990029033748	2	P11802	1
Sema3a pak dependent axon repulsion	0.7943508074618876	2.027273183131924	0.0426344824440567	1.0	0.1540016001739148	6	P07900,Q13177,O14786	3
Activation of the pre replicative complex	0.5317405446491391	2.0044218500696966	0.0450248906583119	1.0	0.161672962896905	19	P33991,P33992,P33993,Q14566,Q07864,P27694,P35244,P49736,P49642,P25205,P56282,P24941	12
Signaling by alk in cancer	0.438051880337279	1.9918856790216517	0.0463836026136843	1.0	0.1656136175298543	33	P33176,O94979,P40763,Q9HC35,P12270,P62993,P19174,P26038,Q14203,P18206,Q00610,P35579	12
Cell cycle mitotic	0.3011559127369489	1.9846540884260837	0.0471829701276718	1.0	0.1677752885838511	229	P31350,Q99460,Q99986,Q01105,Q9Y2S7,Q29RF7,P33993,P48556,Q14739,Q92530,P49721,Q2NKX8,O00487,P62826,P56282,Q9NTJ3,P28070,P00374,P12270,O94927,Q9Y266,Q14738,Q8N3U4,Q16763,O00231,P28340,Q9BTX1,Q9H6D7,P11802,O43242,O95347,P35998,O43237,Q9BRT9,Q15008,P51665,Q14008,P62258,P49736,Q14203,O60763,Q9UNM6,Q13885,Q13200,P20618,Q99436,P33991,P07900,Q9UQE7,Q9Y6G9,Q9P258,Q9UJX3,Q9UL46,P06493,P24941,P33992,Q15021,Q14566,O75935,Q14683,P51530,Q14997,Q13409,Q9BPX3,P08238,P04350,Q86XL3,Q07864,P17612,P55036,Q9HC35,Q14204,P50402,P27361,P28072,P28074,P30260,P25205,Q15154,Q13561,Q8N1F7,Q06323,Q96CW5,P17980,Q9BSJ2,P14635,P49720,P62820,P62140,P37198,P61163,P31751,P28066,P27694,P49642,Q92973,P35251,P04818,P35244,P62191,O75122,Q9Y248	102
Beta catenin independent wnt signaling	0.4003298246158847	1.9765052609476204	0.0480975804873544	1.0	0.1705844240600732	55	P49720,P28066,Q9UL46,O00231,Q99460,O43242,P09496,P48556,Q92530,P49721,Q14997,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P32121,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9HCE1,P17980,Q99436,Q00610	31
Sema4d induced cell migration and growth cone collapse	0.8087901089464427	1.9715111269296737	0.0486654415547131	1.0	0.1717087357948514	5	P35580,P35579	2
Epha mediated growth cone collapse	0.8087901089464427	1.9715111269296737	0.0486654415547131	1.0	0.1717087357948514	5	P35580,P35579	2
Metabolism of amino acids and derivatives	0.2970986680267816	1.965156800774594	0.0493960921258951	1.0	0.1733929490265395	193	Q96HY7,Q9P2J5,P21953,P61254,Q9NR77,O15382,P60866,P62081,P62280,Q13126,P23396,P39023,Q99460,O00231,P46776,P35610,P46783,P62917,P62277,Q99707,O43242,P83881,P17174,P62750,P61353,P48556,Q9BV20,Q92530,P49721,P08243,Q02252,P35998,P57772,P05387,P07814,O00487,P08865,P18077,P62701,Q15008,P51665,P39019,P62899,P26373,P28072,P28074,P34896,P62191,P62861,Q9BV57,P42766,P61927,Q16881,P28070,P62829,Q9UNM6,Q9Y3U8,P62847,Q13200,P17980,P20618,P61457,Q6YP21,P35268,P46782,P46779,Q99436,P52788,P62241	69
Interconversion of nucleotide di and triphosphates	0.5583796776702586	1.958850254955948	0.0501303261704322	1.0	0.1750039549231083	16	Q9H773,Q16881,Q9NRF8,P04818,P17812	5
Arachidonic acid metabolism	0.7466269622719413	1.9588223320356033	0.0501335973044014	1.0	0.1750039549231083	7	Q14914,Q15165,Q9H7Z7	3
Heme degradation	0.975246972794179	1.9579273772608143	0.0502385349048806	1.0	0.1750039549231083	3	P09601	1
Caspase mediated cleavage of cytoskeletal proteins	0.7771129464890674	1.9529799299273247	0.0508219734143629	1.0	0.1765870091478751	6	Q9UJU6,P35611,Q13813	3
Eph ephrin signaling	0.4799453104242279	1.9416507208755376	0.0521793981842284	1.0	0.1800064477507335	25	O15144,Q13177,P35580,P59998,Q7Z406,Q00610,P35579	7
Protein localization	0.373410531096057	1.94147610537892	0.0522005549722726	1.0	0.1800064477507335	69	P09601,P21796,P56589,Q9NS69,O60830,Q9NR77,Q13011,Q10713,P46379,Q99595,Q8N4H5	11
Mhc class ii antigen presentation	0.4015922035189058	1.938034603574155	0.0526190009597229	1.0	0.1809934982760319	51	Q9Y6G9,P61163,P52732,O94979,P09496,O75935,Q13409,P50570,Q15436,P04350,O43237,Q9UQ16,Q14204,P42025,Q14203,Q9H0B6,P33176,Q9BXS5,Q9UJW0,Q9Y496,Q00610	21
Neddylation	0.3703160436933181	1.929315008990077	0.0536917675829302	1.0	0.1833018200025724	70	Q9UBW8,Q99627,P49720,Q9BT78,Q13564,P28066,Q9UL46,Q99460,O00231,Q9Y5A7,Q86VP6,O43242,Q13617,P48556,Q9Y3I1,Q92530,P49721,O60826,Q14997,Q15370,O75832,Q93034,P35998,P25787,O00487,P55036,Q15008,P51665,Q13309,Q13620,P28072,P28074,Q8TBC4,P62191,Q92905,P28070,Q06323,Q9UNM6,Q13200,P20618,Q13619,P61201,P17980,Q99436	44
Golgi to er retrograde transport	0.3789849473028929	1.913353240363727	0.0557028462171342	1.0	0.1859534055003072	65	Q8N6T3,P62820,Q9Y6G9,P61163,Q9Y678,P52732,P53621,O75935,P48444,Q92538,Q13409,Q15363,P04350,Q9NZ32,Q9P2W9,O43237,P24390,Q8TD16,Q14204,P84085,P18085,Q14203,Q9H0B6,P61923,P33176,Q13885,Q9BVK6,Q9UJW0,Q9Y496	29
Antigen processing cross presentation	0.4012895063506947	1.9132019326676124	0.055722206207311	1.0	0.1859534055003072	49	P49720,Q9UIQ6,P28066,Q9UL46,Q99460,O00231,O43242,P48556,Q92530,P09429,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,P04439,P17980,Q99436	29
Sema4d in semaphorin signaling	0.7656461183157276	1.903275303824036	0.0570046315811563	1.0	0.1880466039388024	6	P35580,P35579	2
Rho gtpases activate paks	0.650219349517296	1.8850257434338575	0.0594263622709898	1.0	0.1941639378257401	10	P35580,P35579,Q7Z406	3
Innate immune system	0.2938255419589954	1.8807989256572633	0.059999276376647	1.0	0.1946422022740042	261	P14174,O15144,O60610,P46940,P07900,Q13510,P42785,Q13177,Q14019,P45985,Q9NZQ3,Q9H7Z7,Q9Y6G9,Q9UQB8,Q99536,P07602,Q99460,O00231,P59998,Q15418,Q96JJ3,Q86VP6,Q96G03,Q13576,P09601,O43242,P06737,Q13813,P30519,Q08722,Q13442,P48556,Q07065,Q92530,P09429,P49721,P50570,P08238,P35579,O00487,Q9UQ16,Q13526,Q15008,P51665,Q14204,P06744,Q9NW08,P61086,P28072,P28074,Q6SZW1,P18206,P13798,P62191,Q99829,O75165,P28070,P46976,P62993,P19174,P12956,P04439,Q9UJU6,P17980,Q99436,Q13546,P81605	67
Tp53 regulates transcription of dna repair genes	0.4475120626169118	1.8789260821856344	0.060254586921933	1.0	0.1950083439624737	29	Q14241,P43246,P19447,P23193,P50750,Q14004,Q9NYV4,Q9Y5B9,P18615,Q8WX92,P18074,Q15370	12
Unwinding of dna	0.6635928961748742	1.8658927528567688	0.0620563717435787	1.0	0.199425288537463	9	Q9BRT9,P33991,P33992,P33993,Q14566,P49736,Q9Y248,P25205	8
Cd28 dependent pi3k akt signaling	0.6902896081771868	1.862648527176717	0.06251173214872	1.0	0.2004181763737653	2	P42345	1
Copi independent golgi to er retrograde traffic	0.4638081595335294	1.858439047085449	0.0631066916262272	1.0	0.2018529458792176	26	Q8TD16,O75935,Q9Y6G9,Q14204,P61163,Q14203,Q13409,P04350,O43237	9
Rho gtpases activate wasps and waves	0.5509903744503379	1.8507102220279004	0.0642112526966589	1.0	0.2044307091668049	15	Q9UQB8,Q9NZQ3,P62993	3
Chaperone mediated autophagy	0.686685378848619	1.8263185936328723	0.0678022860678591	1.0	0.213874031398385	8	P08238,P07900,Q9UBN7	3
Mitophagy	0.6171005325940845	1.8027083242161517	0.0714340341855388	1.0	0.2222572563636424	11	Q8N4H5,Q9NS69	2
Hiv elongation arrest and recovery	0.5110623724661236	1.7873046297169115	0.0738882661626862	1.0	0.227822154001616	18	Q14241,P23193,P50750,Q9Y5B9,Q8WX92,Q15370	6
Erbb2 regulates cell motility	0.6715502555366207	1.7689674700453475	0.0768993033868361	1.0	0.2349891659298631	2	O60610	1
Mitotic metaphase and anaphase	0.3061499251579991	1.759937956332032	0.0784183268221621	1.0	0.2390973038297102	126	P14635,P49720,Q9UQE7,Q9Y6G9,Q9P258,P37198,P28066,Q9UJX3,Q9UL46,P06493,O14980,Q99460,Q99986,O00231,Q9BTX1,Q92973,Q29RF7,O43242,Q14683,P48556,Q14739,Q92530,P49721,Q14997,Q13409,Q2NKX8,P04350,P35998,O43237,Q86XL3,O00487,P62826,P55036,Q15008,P51665,Q14008,Q14204,P50402,P28072,P28074,P30260,P62191,Q8N1F7,O75122,P28070,Q06323,Q9UNM6,Q13885,Q99436,Q13200,P17980,P20618,Q16763,Q9Y266,Q14738,Q8N3U4	56
Rho gtpases activate pkns	0.5061813353753105	1.7543589248495493	0.0793690248723553	1.0	0.2414582112227876	18	P62140,P62258,P31946,P27348,Q16513,P35580,Q7Z406,P35579,P63104	9
Rho gtpases activate rocks	0.6691380489017028	1.742145821799623	0.0814829313418634	1.0	0.2467923296615289	8	P35580,P35579,Q7Z406	3
Pink1 prkn mediated mitophagy	0.6673636721984095	1.7336041580350758	0.0829883422016775	1.0	0.2502445825420628	8	Q8N4H5,Q9NS69	2
Signaling by cytosolic fgfr1 fusion mutants	0.7234810614037582	1.7186829859027073	0.0856721117342864	1.0	0.2572042126408732	6	Q16630,O15164,P62993	3
Gap junction trafficking and regulation	0.6006189016884573	1.7140428519253883	0.0865208561314496	1.0	0.258896648627489	11	P09496,P50570,Q07157,P04350,Q00610	5
Iron uptake and transport	0.5193463981100811	1.7103242206426774	0.0872059353465961	1.0	0.258896648627489	16	P30519,P09601	2
Class i peroxisomal membrane protein import	0.6584437164249548	1.6905849172828282	0.0909161073131081	1.0	0.2648173423652023	8	P40855,Q9NR77,P56589	3
Tryptophan catabolism	0.6538330494037583	1.6798404919007242	0.092988354505658	1.0	0.2691354277341349	2	Q6YP21	1
Cdc42 gtpase cycle	0.417532795292158	1.6760632512681894	0.0937258039351025	1.0	0.2701276328150639	30	P46940,O15498,Q13177,Q14739,Q9UQB8,Q86VI3,Q86UP2,Q68EM7	8
Cilium assembly	0.3782335695543535	1.6741631280061695	0.0940985438352606	1.0	0.2706321565346046	50	P07900,P61163,P06493,A0AVF1,Q96A65,Q15019,Q9H6D7,Q92973,O75935,Q10713,Q92538,Q13409,P04350,P17612,Q14204,Q14008,Q9UBN7,P62258,P18085,Q14203,Q8IYI6,Q15154,Q13885,O94927,P17987,Q9UPT5,Q9Y496	27
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation	0.898432174505792	1.6668202439348023	0.0955501536014229	1.0	0.2737532749098406	3	P00374,P07900	2
Apoptotic cleavage of cellular proteins	0.5063570419879735	1.626680823639717	0.103804903580853	1.0	0.2924051707863946	16	Q13813,P35611,P08670,Q9UJU6,Q07157	5
Cooperation of prefoldin and tric cct in actin and tubulin folding	0.5142766112742625	1.621142245326471	0.104987135666384	1.0	0.2947518088719228	15	Q99471,P48643,P78371,Q13885,P61758,P49368,P17987,Q9UHV9,P04350,Q9BVA1	10
Signaling by ntrks	0.3947528333724464	1.6207625288290584	0.1050685775964195	1.0	0.2947518088719228	35	Q00610,Q9UQ16,P50570,P09496,Q14839,P62993,P19174,P31946,Q8WX92,P40763,Q15418,Q9ULH0	12
Dna strand elongation	0.432310568436057	1.6031329300524753	0.1089053091372966	1.0	0.3030312361970714	26	Q9BRT9,P33991,P33992,P33993,Q14566,P49643,P51530,P27694,P35244,P35251,P49736,P49642,Q9Y248,P28340,P25205,Q9Y2S7	16
Mitochondrial protein import	0.3920347624617711	1.5947780877443147	0.1107618687474985	1.0	0.3069493893022782	35	P21796,Q9NS69,O60830,Q10713,Q99595,Q8N4H5	6
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex	0.593563781306236	1.5898043463553204	0.1118789138767699	1.0	0.3087948247929396	10	Q04917,P62258,P31946,P27348,P06493,P63104	6
Rhou gtpase cycle	0.5266301425780645	1.5867635503070134	0.112566207020099	1.0	0.3094440510251316	14	P46940,Q13813,Q13177,P62993,Q01082	5
Cytokine signaling in immune system	0.2739498374326107	1.5772482981556646	0.1147384036883796	1.0	0.3147833159306447	174	P14174,P07900,Q13177,P45985,P37198,Q13126,Q99460,O00231,P61221,Q15418,Q9BTX1,Q9Y3Z3,P09601,Q12899,O43242,Q04637,P48556,P08670,Q92530,P26038,P49721,P09429,Q15370,O00487,P78344,Q00169,Q15008,P51665,P78417,P28072,P28074,P62191,Q8N1F7,P28070,P12270,P62993,P19174,P41240,P04439,P17980,Q99436,P40222,P63104	43
Activation of bad and translocation to mitochondria	0.6344703274366641	1.5743615704996712	0.1154038829048593	1.0	0.315975831393505	8	Q04917,P62258,P31946,P27348,P63104	5
Cd28 co stimulation	0.6860504229520654	1.5527280658733096	0.1204881143256315	1.0	0.328582128509541	6	Q13177,P62993	2
Pyrimidine salvage	0.6279386712095483	1.548759511256551	0.1214395419807066	1.0	0.3305183558083247	2	Q9BZX2	1
Uptake and actions of bacterial toxins	0.6268161782435805	1.5370903714898398	0.1242711804923351	1.0	0.3375540597103308	8	P08238,P07900,Q16881,P45985	4
Abc transporters in lipid homeostasis	0.8641993619724254	1.535576859141408	0.1246421932969155	1.0	0.3378914111355987	3	P56589	1
Signaling by vegf	0.4327454010857796	1.5313035060548796	0.1256943994562902	1.0	0.3388461192473081	24	P07900,Q13177,P19174,Q9UQB8,O14786	5
Methylation	0.6255937554218461	1.531131447280235	0.1257369091144138	1.0	0.3388461192473081	8	P78417	1
Biological oxidations	0.3689519071823691	1.5244383390259884	0.1273992489941207	1.0	0.3419795526920612	42	P07099,Q99707,P30837,Q96KP4,P78417,O43169,Q16850	7
Recycling of eif2 gdp	0.6477815699658713	1.504435552660032	0.1324692558102516	1.0	0.353509573497533	7	P05198,Q13144,Q9NR50,Q14232,Q9UI10,P20042	6
Rac1 gtpase cycle	0.3745005061982964	1.50290090002222	0.1328646009059486	1.0	0.3538747833467776	39	P46940,O15498,Q13177,Q14739,P50402,Q9UQB8,Q86VI3,Q86UP2,Q68EM7	9
Leishmania infection	0.3822299257853063	1.5009046253928462	0.1333802316715613	1.0	0.3545583245793542	35	P09601,Q9NZQ3,P62993,P19174,Q9UQB8,P59998,P35579	7
Metabolism of nucleotides	0.3657180683500237	1.4907106762838729	0.1360374718592059	1.0	0.3609211220450636	42	Q9H773,Q16881,Q9NRF8,O43598,Q05682,P55263	6
Copi dependent golgi to er retrograde traffic	0.3643176559087436	1.4797130598230537	0.138949838827167	1.0	0.3651100371485445	43	Q9H0B6,P61923,Q8N6T3,P33176,P24390,Q9Y496,P53621,P62820,P48444,Q13885,P84085,Q9BVK6,Q9Y678,Q92538,Q15363,P52732,P04350,Q9P2W9	18
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps	0.5243774005218401	1.4722272914600811	0.1409595099447025	1.0	0.3661737554351001	13	Q02818,Q86UP2,Q07065	3
Hiv infection	0.2882734802803917	1.467807598350267	0.1421564929271079	1.0	0.3679293285660051	128	P13010,P23193,P49720,Q13177,P43487,P37198,P28066,Q9UL46,O60942,O14980,Q99460,P18074,O00231,Q9BTX1,O43242,P49917,P50750,P48556,Q92530,P49721,Q9NZZ3,Q8WX92,Q14997,Q15370,Q93034,P35998,O00487,P62826,P19447,P55036,Q15008,P51665,P28072,P28074,P30419,P62191,Q14241,Q9BXS5,Q8N1F7,P28070,Q06323,Q9UNM6,P12270,Q13200,Q13426,P20618,P18615,Q9Y5B9,P12956,P04439,P17980,Q99436,Q8WUM4	53
Rhog gtpase cycle	0.3817085593288452	1.4677474457344184	0.1421728377000852	1.0	0.3679293285660051	33	Q86XL3,Q13576,O15498,Q13177,P49257,Q14739,P50402,P52565,O15173,P61604,Q96JJ3,Q86UP2	12
Binding and uptake of ligands by scavenger receptors	0.6388381727564358	1.462688003209008	0.1435527703380501	1.0	0.3707995143260201	7	Q8WTV0,P07900	2
Signaling by braf and raf1 fusions	0.4099409122614598	1.4605252590449516	0.1441457707166238	1.0	0.3709315039681541	27	P46940,O00203,P30086,P41240,O15164,P31946,P32121,P27361,Q9NRY5,P18206,Q9Y490	11
Rna polymerase iii transcription termination	0.6638748510387893	1.4536982854579987	0.1460299737539596	1.0	0.3743727229759752	6	P05455,Q9NW08	2
Transcription of the hiv genome	0.4136255650791027	1.4503777118283685	0.1469532189116174	1.0	0.3760354330654284	26	Q14241,P23193,P50750,Q9Y5B9,P18615,O60942,Q8WX92,P18074,Q15370	9
Uptake and function of diphtheria toxin	0.7982475911231749	1.4435046754090688	0.1488783563890821	1.0	0.3795427744816637	4	P07900,Q16881	2
Rho gtpase cycle	0.2789892441297468	1.4315158891277728	0.1522824164829792	1.0	0.3867803862063054	140	P46940,P07900,Q13177,Q9BT78,Q9UQB8,Q9Y6M7,Q5VTR2,Q96JJ3,Q8N684,Q99707,Q13813,P30519,Q07065,P08670,Q14739,Q86VI3,Q01082,Q9H2G2,P08238,O75323,Q86XL3,Q08378,P50402,P61604,Q86UP2,Q16543,P38159,O15498,P62993,P41240,P52565,O15173,Q9Y266,Q68EM7	34
Glycogen breakdown glycogenolysis	0.6025156020471777	1.4183528470375266	0.1560877748527247	1.0	0.3957114143951484	8	P06737,P35573,P46976,P46020,Q96G03	5
Disorders of transmembrane transporters	0.323818129065155	1.4147310514434313	0.1571473664770959	1.0	0.3976612656324294	73	P37198,O00231,O95342,Q99460,Q9BTX1,P53985,O43242,P48556,Q92530,P49721,P35613,Q15008,P51665,P28072,P28074,P62191,Q8N1F7,P28070,P12270,P17980,Q99436	21
Rho gtpases activate cit	0.5721420329148001	1.401298041513607	0.1611249666190535	1.0	0.4062248237596395	9	P35580,P35579,Q7Z406	3
Rho gtpases activate ktn1	0.6254397717558657	1.4000285644700348	0.1615047648671637	1.0	0.4064338659984321	7	Q9H0B6,Q86UP2	2
The role of nef in hiv 1 replication and disease pathogenesis	0.5395332540240205	1.38138723552347	0.1671599284826226	1.0	0.4153211290248826	11	Q9BXS5,P04439,Q13177,Q9UI12	4
Fgfr1 mutant receptor activation	0.5922347149351663	1.367980748050753	0.1713181023407146	1.0	0.4210672928266397	8	Q16630,O15164,P62993	3
Rhoh gtpase cycle	0.4490734284597826	1.3647968997250606	0.172316893506923	1.0	0.4217080612807516	18	Q99707,Q13177,P41240,Q9Y6M7,O75323	5
Signaling by erbb2 ecd mutants	0.6436844960398123	1.3632270227965329	0.1728109732494533	1.0	0.4217080612807516	6	P19174,Q16543,P62993	3
Signaling by erbb2 in cancer	0.6436844960398123	1.3632270227965329	0.1728109732494533	1.0	0.4217080612807516	6	P19174,Q16543,P62993	3
Neurotransmitter clearance	0.58977853492333	1.3544121192673737	0.1756049332545233	1.0	0.427189146575417	2	P05091	1
Hiv transcription elongation	0.4171934066460683	1.352219098519604	0.176305235803587	1.0	0.427189146575417	22	Q14241,P23193,P50750,Q9Y5B9,P18615,Q8WX92,P18074,Q15370	8
Sensory perception	0.4168316574936898	1.3494599321387708	0.1771892817952478	1.0	0.4272581458683167	22	P15311,P35241,P26038,Q01082,P35579	5
Formation of atp by chemiosmotic coupling	0.5620212259113395	1.3492595797517737	0.1772536037184138	1.0	0.4272581458683167	9	O75964,P24539,P06576	3
Mtorc1 mediated signalling	0.5322256727918291	1.341328932342753	0.1798136801770347	1.0	0.4311119582528205	11	Q04637,Q15382,P42345,P23588	4
Phase i functionalization of compounds	0.4855694582390729	1.3367068972988774	0.1813183296442035	1.0	0.4316952926659386	14	P07099,P30837,Q16850	3
Endosomal vacuolar pathway	0.769980312510316	1.331473238152084	0.183033345047394	1.0	0.4350219607116014	4	P04439	1
Neutrophil degranulation	0.2566801296326688	1.3298977521227762	0.1835519621636385	1.0	0.4354985029497767	159	P14174,P46940,P07900,P42785,Q14019,Q9H7Z7,Q9Y6G9,Q99536,P07602,O00231,Q86VP6,Q96G03,O43242,Q13813,P30519,Q08722,Q13442,Q07065,P08238,Q15008,P51665,Q14204,P06744,P18206,P13798,O75165,P46976,P12956,P04439,Q9UJU6,P17980,Q99436,Q13510	33
Ub specific processing proteases	0.3147847000987774	1.3227337110809398	0.1859239486259483	1.0	0.4396025659221471	74	Q96K76,P49720,Q9Y4E8,P28066,Q9UL46,Q93008,Q99460,O00231,O43242,P48556,Q92530,P49721,Q14997,Q9UPU5,O75832,P35998,P25787,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,P32121,P45880,P21796,Q06323,Q16186,Q9UNM6,P28070,Q13200,P20618,P17980,Q99436,Q13546	36
Rho gtpases activate iqgaps	0.5425926803360499	1.3201248165749573	0.186793348400275	1.0	0.4401378553527995	10	Q13576,P46940,P04350,Q86VI3	4
Smooth muscle contraction	0.5275899607852875	1.3159084756552573	0.1882047636510573	1.0	0.4426126795086988	11	Q05682,Q13177	2
Nucleotide biosynthesis	0.512764507931212	1.315058390973737	0.1884902791479703	1.0	0.4426126795086988	12	P30520,Q06203,Q05682,P27708,P49915	5
Gap junction degradation	0.6319172379810465	1.3104219697111623	0.1900531254223505	1.0	0.4445065804309321	6	P50570,Q00610	2
Gene and protein expression by jak stat signaling after interleukin 12 stimulation	0.4005987140559318	1.308819234221762	0.1905955900021601	1.0	0.4445065804309321	25	P14174,Q13126,Q13177,P78417	4
Map2k and mapk activation	0.4801424331775628	1.3035655954489236	0.1923817375332854	1.0	0.4470939527960592	14	P46940,Q9Y490,P41240,P31946,P27361,P18206,P32121	7
Signaling by ntrk3 trkc	0.6521022882712296	1.3026778801612475	0.1926847568660883	1.0	0.4470939527960592	5	Q8WX92,P62993	2
Sulfur amino acid metabolism	0.5378268573017876	1.2948257525722833	0.1953803460373055	1.0	0.4513801735286435	10	Q13126,Q99707,Q9BV57	3
Pentose phosphate pathway	0.5761347045499365	1.289016325142305	0.1973924111619593	1.0	0.4541684216482729	8	P11908,Q96G03,P60891,O95336	4
Cellular responses to stimuli	0.2530359821578532	1.281705259474175	0.1999460592561148	1.0	0.4592720723517135	319	P45985,P60866,P62081,P62280,Q99460,P09601,P30519,P61353,P48556,Q92530,P49721,Q9NYB0,Q15370,P51858,P05387,Q9UBN7,P13073,P39019,P62899,P42766,Q16881,P28070,P12270,Q16763,O14773,P43307,Q15382,P61254,O00231,P46783,Q9BTX1,P11802,O43242,O43237,Q15008,P51665,Q14203,P62861,P04150,Q9Y3U8,Q99436,P07900,Q9Y6G9,P42345,Q15418,O94979,P83881,O75935,P35611,Q99543,Q92616,Q13409,P08243,P08238,P04350,Q9Y2L1,Q14204,P26373,P28072,P28074,Q8N1F7,P62847,P35268,P17980,Q8N6T3,P37198,P61163,P23396,P39023,P46776,Q13617,P62750,O60884,P31948,P62701,P35244,P62191,Q02790,Q9UJW0,Q9Y4L1	80
Cholesterol biosynthesis	0.4502988796918414	1.2626169730603396	0.2067268651116323	1.0	0.472469245972996	16	P37268,Q14739,Q9BWD1,Q15125,Q16850	5
Transport of inorganic cations anions and amino acids oligopeptides	0.5700451603501385	1.2591435204481565	0.2079784974047127	1.0	0.4745376049117529	8	Q9Y6M7	1
Methionine salvage pathway	0.6398350783823763	1.2495361506113318	0.2114690397929406	1.0	0.4816990274152008	5	Q13126,Q9BV57	2
Hur elavl1 binds and stabilizes mrna	0.6392427186283418	1.246970417019274	0.2124083449315694	1.0	0.4822338709972115	5	Q01105	1
Constitutive signaling by ligand responsive egfr cancer variants	0.5917215608091562	1.2420263299930951	0.2142268475545587	1.0	0.4839547100696221	7	P19174,Q16543,P62993	3
Signaling by egfr in cancer	0.5917215608091562	1.2420263299930951	0.2142268475545587	1.0	0.4839547100696221	7	P19174,Q16543,P62993	3
Constitutive signaling by egfrviii	0.5917215608091562	1.2420263299930951	0.2142268475545587	1.0	0.4839547100696221	7	P19174,Q16543,P62993	3
Cell surface interactions at the vascular wall	0.4680443731722636	1.2297130247762504	0.2188045876704567	1.0	0.4885595000472297	14	P14174,Q08722,P62993,P19174,P35613,P53985	6
Regulation of localization of foxo transcription factors	0.6135371336966162	1.2279242220946025	0.2194754157526395	1.0	0.4885595000472297	6	P31946,P27348,P63104	3
Formation of tubulin folding intermediates by cct tric	0.4974043815240488	1.2279198475178723	0.2194770580928022	1.0	0.4885595000472297	12	P48643,P78371,Q13885,P50991,Q99832,P49368,P40227,P17987,P04350,Q9BVA1	10
Ire1alpha activates chaperones	0.3970961100230045	1.2229693358801292	0.2213412783414263	1.0	0.4908382639502932	23	O14773,P43307,O94979,P35611,Q14203,P51858	6
Signaling by mapk mutants	0.5638841567291253	1.2223471724354245	0.221576367510059	1.0	0.4908382639502932	2	Q99956	1
Formation of apoptosome	0.5638841567291215	1.2223471724354045	0.2215763675100666	1.0	0.4908382639502932	2	P27361	1
Fbxw7 mutants and notch1 in cancer	0.5611584327086784	1.2084643546749316	0.2268686987540902	1.0	0.4977252425589922	2	Q13616	1
Carboxyterminal post translational modifications of tubulin	0.6302181010941382	1.2078927803590245	0.2270885069742152	1.0	0.4977252425589922	5	P04350,Q14166	2
Mtor signalling	0.4793349381065611	1.2075242885046602	0.2272302970046531	1.0	0.4977252425589922	13	Q04637,Q15382,P42345,P23588	4
Tgf beta receptor signaling in emt epithelial to mesenchymal transition	0.5604770017035676	1.2049946374418603	0.2282053720864949	1.0	0.4990625469431495	2	P61586	1
Inactivation of cdc42 and rac1	0.559795570698457	1.2015253409818636	0.2295474826137344	1.0	0.4999489945884018	2	O94813	1
Nephrin family interactions	0.5576437302806241	1.198337758424208	0.2307855526963058	1.0	0.4999489945884018	8	Q9Y5K6,Q01082,P46940	3
Host interactions of hiv factors	0.2844544346881955	1.1982958199897764	0.2308018733234988	1.0	0.4999489945884018	92	Q13177,P43487,P37198,Q99460,O00231,Q9BTX1,O43242,P50750,P48556,Q92530,P49721,Q15370,O00487,Q15008,P51665,P28072,P28074,P62191,Q8N1F7,P28070,P12270,P04439,P17980,Q99436	24
Diseases associated with glycosylation precursor biosynthesis	0.5306128396206142	1.1876867827727389	0.2349568329652007	1.0	0.5065447312273383	9	P34949	1
Peptide ligand binding receptors	0.6029542516252406	1.1804636516348446	0.2378158589321786	1.0	0.5110987611901924	6	P07602,P42892	2
Class a 1 rhodopsin like receptors	0.6029542516252406	1.1804636516348446	0.2378158589321786	1.0	0.5110987611901924	6	P07602,P42892	2
Diseases of mismatch repair mmr	0.7716428084526213	1.1793501634832106	0.2382587710445176	1.0	0.5112480526017941	3	P43246,P20585	2
Signaling by wnt	0.2931269640377673	1.16688762181508	0.2432557553548577	1.0	0.5203392641887504	84	Q13616,P49720,P48729,P31751,P28066,Q9UL46,O14980,Q99460,O00231,O43242,P09496,P48556,Q92530,P49721,Q96QK1,Q14997,O75832,Q9UBQ0,P35998,P25787,O00487,P61586,P55036,Q15008,P51665,Q13363,P28072,P28074,P62191,P32121,P28070,Q06323,Q9UNM6,Q99436,Q13200,P20618,Q9HCE1,P07737,P17980,Q14738,Q00610,P63104	42
Heme biosynthesis	0.7273193465578693	1.162623482259224	0.24498229911684	1.0	0.5225372162857941	4	P06132,P22830	2
Assembly of the hiv virion	0.5516183986371279	1.159931470441538	0.2460767085264019	1.0	0.5225372162857941	2	Q9NZ09	1
Rna polymerase iii chain elongation	0.6173325668544929	1.1521597027672392	0.2492554534263307	1.0	0.5226146044835632	5	Q9NW08	1
Rna polymerase iii transcription initiation from type 3 promoter	0.6173325668544929	1.1521597027672392	0.2492554534263307	1.0	0.5226146044835632	5	Q9NW08	1
Signaling by hippo	0.617317499882827	1.1520945958509212	0.2492822035995374	1.0	0.5226146044835632	5	P62258,P31946,Q07157	3
Vldlr internalisation and degradation	0.572075050205422	1.1500463310872466	0.2501247892801967	1.0	0.5230209870124342	7	Q00610	1
Interleukin 12 signaling	0.3726832133871971	1.1496632366091384	0.2502826017258746	1.0	0.5230209870124342	27	P14174,Q13126,Q13177,P78417	4
Signaling by fgfr1 in disease	0.5102988063374574	1.1488394663015675	0.2506221822353227	1.0	0.5230209870124342	10	Q16630,P19174,O15164,P62993	4
Mismatch repair	0.4956240030839292	1.1407933886388362	0.2539559125269193	1.0	0.5291714524343265	11	P43246,P20585,P35244,P28340,Q9Y2S7	5
Synthesis of active ubiquitin roles of e1 and e2 enzymes	0.5211395501014878	1.1390497470763266	0.2546824057480545	1.0	0.5295703807054996	9	Q16763,P61086,P22314,Q93008	4
Cd28 dependent vav1 pathway	0.7202509727159251	1.1347519028202644	0.2564792837053731	1.0	0.5320002112009936	4	Q13177	1
Activation of ampk downstream of nmdars	0.6125741110009977	1.1316065536905695	0.2577998835720372	1.0	0.5331857739758958	5	Q13131,Q13885,P04350	3
Pten regulation	0.3112086590036526	1.131262864008459	0.2579444697275646	1.0	0.5331857739758958	67	Q15382,P49720,P31751,P42345,P28066,Q9UL46,Q99460,O00231,Q99496,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P27361,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9HCE1,Q14839,P17980,Q99436	33
Dna replication initiation	0.5918209583454804	1.1306100375441988	0.2582192608809488	1.0	0.5331857739758958	6	Q07864,P49642,P56282	3
Recruitment of mitotic centrosome proteins and complexes	0.3777395038517511	1.1256629424266775	0.2603082149907412	1.0	0.5358826260486086	25	P07900,Q9BSJ2,Q96CW5,O75935,Q14204,P06493,Q14203,Q13409,P04350,Q9H6D7	10
Sema3a plexin repulsion signaling by inhibiting integrin adhesion	0.7558864411889501	1.1190296194744132	0.2631275031133824	1.0	0.5400622964950832	3	O14786	1
Synthesis of bile acids and bile salts	0.5887057137974705	1.116679691785844	0.2641313040648354	1.0	0.5405018763299846	6	O95342	1
Bile acid and bile salt metabolism	0.5887057137974705	1.116679691785844	0.2641313040648354	1.0	0.5405018763299846	6	O95342	1
Lysosome vesicle biogenesis	0.4775735276639478	1.1156907295307763	0.2645545401360194	1.0	0.54055994842718	12	Q9BXS5,P09496,P50570,Q00610,P20645	5
Metabolism of steroids	0.3316597619007064	1.093387196734951	0.2742238325528776	1.0	0.5537056441960022	40	P30536,P37268,Q14739,Q9BWD1,O95342,Q15125,Q16850	7
Cyclin d associated events in g1	0.4994443112808278	1.0914786280763358	0.2750623309665239	1.0	0.5545807527145379	10	Q00534,P11802,P63151,Q13309,P30154,P24941,Q13616,P30153	8
Vxpx cargo targeting to cilium	0.5337370476926522	1.0814563017304206	0.2794941887715625	1.0	0.5623740297664693	8	P18085,Q92538,Q9UPT5,Q8IYI6,Q96A65	5
Recruitment of numa to mitotic centrosomes	0.3545660304775708	1.0732548569852514	0.2831567837354773	1.0	0.5677704789140756	29	P07900,Q9BSJ2,Q96CW5,O75935,Q14204,P06493,Q14203,Q13409,P04350,Q9H6D7	10
Signaling by rho gtpases miro gtpases and rhobtb3	0.2589744854586877	1.0720938684997856	0.2836778725911086	1.0	0.5677704789140756	227	O15144,O60610,P46940,P07900,Q13177,Q9Y6G9,Q9BT78,Q9NZQ3,P62140,Q9UQB8,P31946,Q9Y6M7,Q5VTR2,P59998,Q96JJ3,Q8N684,Q13576,Q99707,Q13813,P30519,P49257,Q07065,P08670,Q14739,Q86VI3,Q13409,Q01082,P31948,Q2NKX8,Q9H2G2,P08238,P04350,Q14126,O75323,P35579,O43237,Q86XL3,Q12979,Q08378,Q14204,P50402,P61604,Q9H0B6,Q86UP2,Q16543,P33176,O75122,P38159,O15498,P62993,P41240,P52565,Q92974,P35580,O15173,P35080,Q7Z406,Q9Y266,Q00610,Q68EM7,P63104	61
Regulation of tp53 expression and degradation	0.506904500239478	1.0661837281717974	0.2863405962898264	1.0	0.5714289742285312	9	O96017,P31751,P42345,P06493,P24941,P30153	6
Galactose catabolism	0.7013128506215651	1.0603398588787467	0.2889900120290645	1.0	0.575039718703182	4	Q14376	1
Ripk1 mediated regulated necrosis	0.5053335279164335	1.0581636327133723	0.2899808480772035	1.0	0.5753388130691183	9	Q16543,P07900,Q13546,P49327	4
Intraflagellar transport	0.4802625857194681	1.0570622371584708	0.2904831841855719	1.0	0.575501417004411	11	A0AVF1,Q9Y496,P04350	3
Signaling by moderate kinase activity braf mutants	0.4183297820793383	1.0553972478807792	0.2912436810501042	1.0	0.5761742765283131	16	P46940,Q9Y490,P41240,P31946,P27361,P18206,P32121	7
Cell cycle	0.2556792175421355	1.0492815427535918	0.2940485583280716	1.0	0.5783799947573708	274	P33991,P07900,Q9BSJ2,P62820,Q9UQE7,Q9Y6G9,P62140,P61163,P37198,P31946,P31350,P06493,Q99460,Q99986,O00231,P49642,Q01105,Q9BTX1,Q9Y2S7,Q9H6D7,Q29RF7,Q92973,P33993,P11802,O43242,O95347,Q15021,Q14566,O75935,P48556,Q14739,Q92530,P49721,P35251,Q13409,Q9NYB0,Q2NKX8,P08238,P04350,O60921,O43237,Q9BRT9,O00487,P62826,Q86XL3,Q9HC35,Q15008,P51665,Q14204,P04818,P50402,P35244,Q14203,P28072,P28074,P62191,P56282,Q9NTJ3,O60763,Q8N1F7,P28070,O75122,P00374,P12270,Q96CW5,P17980,Q9Y248,Q9Y266,Q99436,Q16763,P63104	71
Vitamin b5 pantothenate metabolism	0.7348329925017001	1.0388709591254717	0.2988647542591609	1.0	0.5832934793398479	3	Q9NRN7,P49327	2
Rac3 gtpase cycle	0.3543137672673454	1.032546656220583	0.3018161028556037	1.0	0.5872976363043326	28	O15498,Q13177,P49257,Q14739,P50402,Q9UQB8,O15173,Q68EM7,Q14126	9
Caspase activation via extrinsic apoptotic signalling pathway	0.7322734782581336	1.0291691347683682	0.3034002034835681	1.0	0.5883213577464657	3	Q13546	1
Interleukin 12 family signaling	0.3434345408644781	1.0184947279085232	0.3084429050250106	1.0	0.5953666166212639	30	P14174,Q13126,Q13177,P78417	4
Formation of rna pol ii elongation complex	0.3525446115245264	1.0177220838441978	0.3088100492548271	1.0	0.5953666166212639	28	Q14241,P23193,P50750,Q9Y5B9,P18615,Q8WX92,P18074,Q15370,Q6PD62	9
Response of eif2ak1 hri to heme deficiency	0.729038854805721	1.016923743403332	0.3091897072432912	1.0	0.5953666166212639	3	P08243,P05198	2
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways	0.5428129873115897	1.0137898190621992	0.3106830543272951	1.0	0.5965288939327729	7	P09601	1
Constitutive signaling by overexpressed erbb2	0.5832207025332096	1.0053896952479489	0.3147092398635327	1.0	0.6017275829234306	5	Q16543,P62993	2
Oncogenic mapk signaling	0.3325965698048132	1.0024006005982269	0.3161501521785383	1.0	0.60363955137018	32	P46940,Q99956,P62140,O00203,P30086,P41240,O15164,P31946,P32121,P27361,Q9NRY5,P18206,Q9Y490	13
Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters	0.4809131286975798	0.9940909715542636	0.320178580401282	1.0	0.6104797723807173	10	Q9BXS5,P04439,Q9UI12	3
Synthesis of pips at the golgi membrane	0.5787347362520895	0.9862189978515544	0.3240256586702901	1.0	0.6160987871105933	5	Q10713,Q9BTU6	2
Inhibition of replication initiation of damaged dna by rb1 e2f1	0.5763574859396757	0.976076154909955	0.3290267268811451	1.0	0.6238747771472127	5	P49643,P49642,P30153	3
Metabolism of folate and pterines	0.5331016410110205	0.968913001478041	0.3325885979449574	1.0	0.6280190214988232	7	P00374,Q9H2D1	2
Rap1 signalling	0.7150647580095388	0.9642401755227044	0.3349255264328339	1.0	0.6315606689897377	3	P31946,P63104	2
Ikk complex recruitment mediated by rip1	0.7120491169247632	0.9529221492364556	0.3406295167933524	1.0	0.6391031938631382	3	Q6SZW1	1
Aryl hydrocarbon receptor signalling	0.7119631975223588	0.9525999719164489	0.3407927914682913	1.0	0.6391031938631382	3	P08238	1
Cytosolic trna aminoacylation	0.3611607993848152	0.9475211567638344	0.3433732806891445	1.0	0.6413069867168334	23	P26639,P07814,P49591,Q9P2J5,Q12904,P47897,Q9Y285,P41252,P49588,P26640,P54577,Q13155	12
Transcriptional regulation by runx1	0.3004502641325188	0.9457272201227622	0.3442877351604192	1.0	0.6421388411915722	63	Q99873,P49720,P28066,Q9UL46,Q99460,O00231,Q99496,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P55036,Q15008,P51665,P28072,P28074,P62191,Q07157,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9HCE1,P17980,Q99436	30
Activation of smo	0.7089297886843835	0.9412358964543288	0.3465839850089538	1.0	0.6442011896156664	3	Q9Y496,P48729	2
Costimulation by the cd28 family	0.458151990404722	0.9376132329494662	0.3484432083776974	1.0	0.6442011896156664	11	Q13177,P42345,P62993	3
Influenza infection	0.2579359695921204	0.9353118610987288	0.3496276044146262	1.0	0.6443682125217373	124	P07900,P61254,P37198,P60866,P62081,P62280,P23396,P39023,P46776,P46783,Q9BTX1,P62917,P62277,P09496,P83881,P62750,P61353,P05387,P08865,P62826,P18077,P62701,P39019,P62899,P26373,P62861,P42766,P61927,Q8N1F7,P62829,P12270,Q9Y3U8,P62847,P35268,P46782,P46779,Q00610,P62241	38
Downregulation of erbb2 signaling	0.547800846807384	0.9351340943412912	0.3497191978843321	1.0	0.6443682125217373	6	Q93034,P07900,Q16543,P31751	4
Folding of actin by cct tric	0.5018777739842988	0.9272627220331308	0.3537901442142672	1.0	0.646947453419839	8	P48643,P78371,P50991,Q99832,P49368,P17987,P40227	7
Establishment of sister chromatid cohesion	0.5239723501938771	0.9269462343120376	0.3539544504101237	1.0	0.646947453419839	7	Q29RF7,Q9UQE7,Q14683,Q8N3U4	4
Purinergic signaling in leishmaniasis infection	0.660733094374872	0.9028724680936302	0.3665935842488417	1.0	0.6646671870434916	4	P09601	1
Inflammasomes	0.660733094374872	0.9028724680936302	0.3665935842488417	1.0	0.6646671870434916	4	P09601	1
The nlrp3 inflammasome	0.660733094374872	0.9028724680936302	0.3665935842488417	1.0	0.6646671870434916	4	P09601	1
Translocation of slc2a4 glut4 to the plasma membrane	0.3214768156466273	0.9020171316152316	0.3670477672789478	1.0	0.6646671870434916	32	Q04917,Q9UIQ6,Q13885,P63104,P31751,P62258,P31946,P27348,Q9UPT5,Q9Y496,Q8IYI6,Q96A65,P04350,Q86X10,P35579	15
Generation of second messenger molecules	0.655158323744457	0.8815324562630369	0.3780296950170669	1.0	0.6800560479347761	4	P19174,Q13177	2
Deubiquitination	0.2606822178721975	0.8774475297222423	0.3802436066297168	1.0	0.6813527453875423	93	Q96K76,P49720,Q9Y4E8,P28066,Q9UL46,P06493,Q93008,Q99460,O00231,Q99496,O43242,P48556,Q92530,P49721,Q14997,Q9UPU5,O75832,O95630,P35998,P25787,O00487,P61586,P55036,Q15018,Q15008,P51665,P28072,P28074,P62191,P45880,P32121,P54727,P21796,P28070,Q06323,Q9UNM6,Q16186,Q13200,P20618,P17980,Q99436,Q13546	42
Mitotic prometaphase	0.2755145177472376	0.869423425786407	0.3846155746168431	1.0	0.6867432362348419	79	Q9NTJ3,P07900,Q15021,Q9BSJ2,O95347,Q9HC35,O75935,Q96CW5,Q9UQE7,Q9Y6G9,Q14204,P06493,Q14203,Q13409,Q9Y266,P04350,Q9H6D7,O43237	18
Protein ubiquitination	0.3531094021038006	0.8693418528010606	0.3846601772860873	1.0	0.6867432362348419	22	Q9GZS3,Q15819,P78527,P68036,O75150,P04439,Q5VTR2,Q93008,P61086,Q16763,Q6PD62,P22314	12
Hsf1 activation	0.4208605866384527	0.8682856987254728	0.3852379492738589	1.0	0.6867432362348419	13	P07900,Q9UBN7,P0DMV9,P62258,P35244,Q02790,P08238	7
Cyclin a b1 b2 associated events during g2 m transition	0.4449227421775324	0.8670514810585853	0.3859138031012252	1.0	0.6867432362348419	11	P14635,O14980,P06493,P30153,P24941	5
Nuclear events stimulated by alk signaling in cancer	0.4328809539478286	0.8664166473137158	0.3862617179699257	1.0	0.6867432362348419	12	P33176,P28482,Q9HC35,P27361,P40763,Q13616,Q86WB0,Q00610	8
Signaling by flt3 fusion proteins	0.5490207437730701	0.8604426193386506	0.3895451010104636	1.0	0.6911538244441795	5	P62993	1
Vegfr2 mediated vascular permeability	0.4660882407983475	0.860066850395111	0.3897521931854686	1.0	0.6911538244441795	9	P07900,Q13177	2
Signaling by notch3	0.5286221824881734	0.8513947737051528	0.3945500939673116	1.0	0.6960555137129506	6	P67809	1
Eph ephrin mediated repulsion of cells	0.4620876504395219	0.8402065942126593	0.4007925617543304	1.0	0.7055314808569121	9	Q00610	1
Signaling by erbb2	0.4280345740432264	0.8399219509496771	0.4009521490918024	1.0	0.7055314808569121	12	P19174,Q16543,P62993	3
Asparagine n linked glycosylation	0.2523838047313061	0.8226461314424083	0.4107092569841297	1.0	0.7148138074214392	106	Q8N6T3,Q86SZ2,P62820,Q9Y6G9,P61163,Q9Y678,Q8IUR0,O94979,P53621,Q13813,O75935,P48444,P49257,Q9Y5P6,Q92538,Q13409,Q01082,Q15363,Q15436,P04350,Q9NZ32,O43237,P24390,Q9BT22,Q16706,P34949,Q14204,P84085,P18085,Q14203,P62191,Q16222,P54727,P61923,Q13561,O60763,O15498,O43617,Q13885,Q9BVK6,Q9NYU2,Q9UJW0	42
G1 s specific transcription	0.4364362397236819	0.8222641699276898	0.4109265642371604	1.0	0.7148138074214392	11	P00374,P06493,P04818	3
Wnt5a dependent internalization of fzd2 fzd5 and ror2	0.4791843772556656	0.8194077137080121	0.4125538354139877	1.0	0.7167337572103416	8	Q00610	1
Cytosolic iron sulfur cluster assembly	0.5000355748063453	0.8182334484167507	0.4132238992620167	1.0	0.7169879823697096	7	P28340,O75027,P53384,P18074	4
Nef mediated downregulation of mhc class i complex cell surface expression	0.63723643931533	0.8135590547421058	0.4158976024022114	1.0	0.7169981833948216	4	Q9BXS5,P04439	2
Anchoring of the basal body to the plasma membrane	0.337672979719426	0.8119860912443402	0.4167996124702995	1.0	0.7169981833948216	25	P07900,O75935,Q14204,P61163,P06493,Q14203,Q13409,P04350,Q9H6D7	9
Activation of atr in response to replication stress	0.3600247723205019	0.8092141320083334	0.4183919875184321	1.0	0.7169981833948216	19	P33991,P33993,P33992,Q14566,P35244,P49736,P25205,O60921,P24941	9
Intrinsic pathway for apoptosis	0.3794540808354688	0.8090834194714652	0.4184671647424853	1.0	0.7169981833948216	16	Q04917,P62258,P31946,P27348,P27361,P30419,P40763,P63104	8
Fceri mediated ca 2 mobilization	0.672110133775836	0.8052266295725273	0.4206889121785806	1.0	0.7190405316226472	3	P62993	1
P75ntr regulates axonogenesis	0.6717791411042886	0.8040228414434594	0.4213837835709006	1.0	0.7190405316226472	3	P52565,Q9NQC3	2
Intracellular signaling by second messengers	0.2656967965405354	0.8017277422539212	0.4227104644781059	1.0	0.7197644600379689	84	Q15382,P49720,P42345,P31751,P28066,Q9UL46,Q99460,O00231,Q99496,O43242,P48556,Q92530,P49721,Q14997,O75832,P35998,O00487,P17612,P55036,Q15008,P51665,P27361,P28072,P28074,P62191,P28070,Q06323,Q9UNM6,Q13200,P20618,Q9HCE1,P62993,P19174,Q14839,Q14738,P17980,Q99436	37
Golgi cisternae pericentriolar stack reorganization	0.443353850253271	0.800413201567915	0.4234714347301329	1.0	0.7201644647770832	10	P06493,O60763	2
Regulation of plk1 activity at g2 m transition	0.3169208637034911	0.7909111616096812	0.4289958346039282	1.0	0.7272082144603719	30	P07900,O75935,P62140,Q14204,P06493,Q14203,Q13409,P04350,Q9H6D7	9
Ncam signaling for neurite out growth	0.5132527356303814	0.7852521076593814	0.4323057695715633	1.0	0.7288501650813213	6	Q01082,P62993	2
Ngf stimulated transcription	0.6657564637275277	0.7821874287137147	0.4341044314259457	1.0	0.7297760698434341	3	P50570	1
Cohesin loading onto chromatin	0.4710266823006244	0.7812135877545447	0.4346768833713437	1.0	0.7297760698434341	8	Q29RF7,Q9UQE7,Q14683,Q8N3U4	4
Bbsome mediated cargo targeting to cilium	0.5121829639623752	0.780686247470204	0.4349870511265465	1.0	0.7297760698434341	6	P78371,P49368,P48643,P17987	4
Rhoc gtpase cycle	0.3326533965501012	0.7739435921391087	0.4389641493695997	1.0	0.7339088089368151	25	O60610,P46940,P49257,Q14739,P52565,Q86VI3,Q9H2G2	7
Processive synthesis on the lagging strand	0.4157059135336214	0.7732202501178256	0.439392043716913	1.0	0.7339088089368151	12	P51530,P27694,P35244,P49642,P28340,Q9Y2S7	6
Synthesis of prostaglandins pg and thromboxanes tx	0.6260948949008918	0.7718584546780972	0.44019826590735	1.0	0.7339088089368151	4	Q9H7Z7	1
Mastl facilitates mitotic progression	0.6256392771905982	0.7701632994905068	0.4412030312308115	1.0	0.7339088089368151	4	P06493,P14635,P30153	3
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism	0.6256392771905921	0.7701632994904847	0.4412030312308246	1.0	0.7339088089368151	4	Q14738,P17612,P30153	3
Inactivation of csf3 g csf signaling	0.6252829425213715	0.7688381124027464	0.4419894204628785	1.0	0.7339540804442394	4	Q15370,P40763	2
Telomere c strand synthesis initiation	0.6246807146133918	0.766599624550427	0.4433195987757798	1.0	0.7342714380606689	4	Q9NYB0,P49642	2
Deadenylation of mrna	0.3746039659957789	0.745888832398796	0.4557345718989609	1.0	0.7471911979221939	15	O75175,Q9H9A5,Q04637,Q9C0C2,P23588,Q14240,P11940,Q9UIV1	8
Termination of translesion dna synthesis	0.3633358145933851	0.7458839701643571	0.4557375093243476	1.0	0.7471911979221939	17	Q07864,P35244,P35251,P28340,P56282,Q9Y2S7	6
Organelle biogenesis and maintenance	0.2637141999555721	0.743110416281976	0.4574148338119532	1.0	0.7490441477135933	81	P07900,P61163,P06493,A0AVF1,Q96A65,Q15019,Q9H6D7,O75935,O75964,Q10713,Q13409,P04350,Q14204,Q9UBN7,P06576,Q14203,Q04837,P24539,Q9Y496	19
Nuclear events kinase and transcription factor activation	0.3982545485952041	0.7417150944662153	0.4582599723981362	1.0	0.7495315438626624	13	P50570,Q14839,P27361,Q15418,Q14738,Q16539,P30153	7
Fceri mediated mapk activation	0.4412749625262543	0.7383262529829256	0.4603162168755337	1.0	0.7519963017930855	9	P19174,Q13177,P62993	3
Insulin processing	0.4603030422844354	0.7315789887947234	0.4644255765313896	1.0	0.7542095068463492	8	P33176,Q9UPT5,Q8IYI6,Q96A65	4
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects	0.6509884117245991	0.7292363515333917	0.4658570984940731	1.0	0.7556378765857654	3	P11802,P24941	2
Potential therapeutics for sars	0.2990972369270713	0.7214586389252226	0.4706273796430924	1.0	0.7606716443109723	35	P04150,P07900,Q14839,Q13546,Q02790,Q99720,P08238	7
Transport of connexons to the plasma membrane	0.6109745709133539	0.7160693139774368	0.4739485504416421	1.0	0.7642350595460635	4	Q13885,P04350	2
Gap junction assembly	0.6109745709133539	0.7160693139774368	0.4739485504416421	1.0	0.7642350595460635	4	Q13885,P04350	2
Fanconi anemia pathway	0.4744734373509761	0.7050368686704644	0.4807872924192278	1.0	0.7690454618696143	7	Q92889,P35244,Q9NVI1	3
Recognition of dna damage by pcna containing replication complex	0.3485192614322883	0.6913549802290383	0.4893424884561532	1.0	0.778467479797153	18	Q07864,Q13620,P27694,P35244,P35251,P28340,P56282,Q9Y2S7	8
Netrin 1 signaling	0.4514038324142937	0.6909525596779104	0.4895953544211808	1.0	0.778467479797153	8	P15311,P19174	2
Toll like receptor cascades	0.3215032833141105	0.6909473758503398	0.4895986122025921	1.0	0.778467479797153	25	Q9UQ16,P50570,P45985,P09429,Q6SZW1,Q15418,Q13546	7
Diseases of mitotic cell cycle	0.3862916716953629	0.6765425213976971	0.4986962584930519	1.0	0.7892661015918937	13	P11802,Q13309,Q9UJX3,P30260,Q16763,P24941	6
Rnd2 gtpase cycle	0.3574625288984509	0.675446809888091	0.4993919340778672	1.0	0.7894544546796768	16	Q9Y266,Q08378,Q07065,Q86UP2	4
Tp53 regulates transcription of cell cycle genes	0.3569848261311336	0.6726096379236856	0.5011956685274144	1.0	0.7913920071672783	16	Q99873,P14635,O75175,Q9H9A5,P06493,Q9C0C2,Q9UIV1,P24941	8
Interleukin 17 signaling	0.3613927598986804	0.6683257026161735	0.5039257100791668	1.0	0.7929589621820451	15	Q02750,P28482,P63208,P45985,P30154,P27361,Q14738,Q15418,Q13616,Q16539,P30153	11
Nucleotide salvage	0.4639235494606986	0.6594677899037659	0.5095954232287077	1.0	0.8009599706086117	7	P55263	1
Cargo trafficking to the periciliary membrane	0.3541707144221647	0.65596102368968	0.511849202633383	1.0	0.801740913506981	16	Q10713,P18085,Q92538,P17987,Q9UPT5,Q8IYI6,Q96A65	7
Signaling by fgfr4 in disease	0.6283511182880535	0.6499492996509695	0.5157249717740817	1.0	0.8066403056190941	3	P62993	1
Rac2 gtpase cycle	0.2991116456388672	0.6450465170855809	0.518897041259692	1.0	0.8090858105264487	30	Q86XL3,P46940,Q13177,P49257,Q14739,P50402,P52565,O15173,Q68EM7,Q14126	10
Hdr through homologous recombination hrr	0.3211574950187055	0.6421817438666928	0.5207551851181391	1.0	0.8090858105264487	22	Q07864,P51530,P35244,P35251,P28340,P56282,O60921,Q9Y2S7	8
Pp2a mediated dephosphorylation of key metabolic factors	0.6254260395364617	0.6398918339098415	0.5222429232480164	1.0	0.8090858105264487	3	Q14738,P30153	2
E2f mediated regulation of dna replication	0.4098781279306318	0.6351068331020717	0.5253587408011484	1.0	0.8090858105264487	10	P49643,P14635,P30154,P06493,P49642,P30153	6
Signaling by receptor tyrosine kinases	0.2381103812420478	0.6286080053166538	0.5296057181207545	1.0	0.8128141570709786	103	O60610,P07900,Q13177,P42345,P16949,Q9UQB8,P31946,Q15418,Q96JJ3,P09496,Q8WX92,Q96P70,P50570,Q9UQ16,Q16543,Q9ULH0,Q14839,P62993,P19174,P41240,P61201,O14786,P40763,Q14738,Q00610	25
Formation of incision complex in gg ner	0.354280707635103	0.6275036905284589	0.5303291177904801	1.0	0.8129467887843848	15	P19447,Q15819,Q92889,Q13620,P27694,P35244,P18074,P09874,P54727	9
Processive synthesis on the c strand of the telomere	0.3969824760262643	0.6210469638865235	0.5345687232918397	1.0	0.8176810974151157	11	P51530,P35244,Q9NYB0,P28340,Q9Y2S7	5
Fcgr3a mediated il10 synthesis	0.5834401934063126	0.6173330670855959	0.5370150603594914	1.0	0.8193754378962506	4	P19174	1
Cell cell communication	0.3221525585698148	0.6166038608328339	0.5374960473430184	1.0	0.8193754378962506	21	Q9Y5K6,P46940,Q13813,P62993,Q01082	5
Initiation of nuclear envelope ne reformation	0.3470423956174522	0.6143138496958775	0.5390079522615474	1.0	0.8193754378962506	16	Q14739,Q86XL3,P06493	3
Global genome nucleotide excision repair gg ner	0.2827675169806615	0.6135083385921083	0.5395402708721646	1.0	0.8193754378962506	39	Q9UBW8,Q99627,P19447,Q15819,Q9BT78,Q13620,P35244,P35251,P61201,P18074,P28340,P56282,Q9Y2S7,P54727	14
Metabolism of nitric oxide nos3 activation and regulation	0.4521313047279832	0.6094998194537514	0.542193192383384	1.0	0.8202092349425332	7	P07900,P35270	2
Slc mediated transmembrane transport	0.3349761359731379	0.6076578570909512	0.5434144192257828	1.0	0.8202142667255752	18	Q70HW3,Q9Y6M7,P53985	3
Purine ribonucleoside monophosphate biosynthesis	0.4122494299043924	0.6015569165307759	0.5474691146224437	1.0	0.82271994809023	9	Q06203,P30520,P49915	3
Role of abl in robo slit signaling	0.6131561008861547	0.5982249350231825	0.54968985571171	1.0	0.8251375136725121	3	Q01518,O75122	2
Dag and ip3 signaling	0.4488147109310174	0.595649263635889	0.5514095589709012	1.0	0.8268123616989745	7	P19174,P17612	2
Golgi associated vesicle biogenesis	0.309555721429625	0.5888940542953666	0.5559323465072605	1.0	0.8308639545506984	24	O00443,Q9BXS5,P09496,O60749,Q14671,O00203,P02786,P50570,Q00610	9
Rhobtb gtpase cycle	0.3041837142938414	0.5846921318551523	0.558754745535083	1.0	0.8325039144918472	26	P07900,P38159,Q9BT78,Q5VTR2,P08238,Q16543,Q8N684	7
Regulated necrosis	0.3682664708963441	0.5814397653487549	0.5609441034108409	1.0	0.8338534809204533	13	P07900,P49327,P09429,Q13546,Q16543	5
Glycogen metabolism	0.3786308606604511	0.5808185283024376	0.5613627662098388	1.0	0.8338534809204533	12	P46020,P46976,Q96G03	3
G2 m dna replication checkpoint	0.6078509876224162	0.5804855568957583	0.5615872238193265	1.0	0.8338534809204533	3	P06493	1
Phosphorylation of the apc c	0.3871706683406523	0.5733809890985342	0.5663867594634413	1.0	0.8374906916830274	11	Q9UJX3,Q16763,P06493,P30260	4
Cytoprotection by hmox1	0.2658032591445913	0.5732375801034976	0.5664838425847212	1.0	0.8374906916830274	63	P09601,O43242,P28070,P30519,Q15008,P51665,P13073,P49721,P28072,O00231,P28074,Q99436	12
Phosphorylation of emi1	0.5701109523745052	0.5711126689506989	0.5679232713229339	1.0	0.8387130080270727	4	P06493,P14635	2
Mitochondrial calcium ion transport	0.3384174785780225	0.5650273428809703	0.57205516635522	1.0	0.8439046581253192	16	Q10713,P45880,P21796	3
Myd88 independent tlr4 cascade	0.3136854060689295	0.56168100407876	0.5743333790273055	1.0	0.845087685643684	21	Q02750,Q13616,P45985,P09429,P27361,Q6SZW1,Q15418,Q14738,Q13546,Q16539,P30153	11
Oncogene induced senescence	0.4587881943619131	0.5613408735437598	0.5745651827167442	1.0	0.845087685643684	6	P11802,Q9HCE1,P27361	3
Estrogen dependent nuclear events downstream of esr membrane signaling	0.5642686668939598	0.5512246096368377	0.581479711889731	1.0	0.8529415866199778	4	O14980,P27361,P31751	3
Signaling by notch1 pest domain mutants in cancer	0.4179755545046948	0.5441111649573047	0.586364977830176	1.0	0.8557928087947879	8	Q9UBN7	1
Basigin interactions	0.4694557434239047	0.5423919512211168	0.5875485232053446	1.0	0.8566069523622116	5	P53985	1
Immunoregulatory interactions between a lymphoid and a non lymphoid cell	0.4526964648493922	0.5376582871408271	0.5908129819399797	1.0	0.8604499705062044	6	P04439	1
Muscle contraction	0.3097516900194415	0.5367299050667912	0.591454195930085	1.0	0.8604684316984976	21	Q05682,Q13177	2
Rhoq gtpase cycle	0.3130101221171512	0.5321558259144514	0.594618075025658	1.0	0.8615705565014292	20	Q9Y6M7,P46940,Q13177,Q68EM7	4
Insertion of tail anchored proteins into the endoplasmic reticulum membrane	0.3878032733700699	0.5319954775521875	0.5947291277529954	1.0	0.8615705565014292	10	P09601,P46379	2
Unfolded protein response upr	0.2713520476232846	0.5256933816025249	0.5991012630167101	1.0	0.8669869229068458	40	O14773,P43307,O94979,Q9Y2L1,P08243,P35611,Q14203,P51858	8
Gastrin creb signalling pathway via pkc and mapk	0.4492413899562639	0.5243768444261054	0.6000164586757775	1.0	0.8673944370930722	6	P62993	1
Translesion synthesis by y family dna polymerases bypasses lesions on dna template	0.3110317834299368	0.520103773888045	0.6029912481995399	1.0	0.8707753362712765	20	Q07864,P35244,P35251,P28340,P56282,Q9Y2S7	6
Regulation of mecp2 expression and activity	0.3754792767323411	0.518182791607908	0.6043307400426476	1.0	0.8712497280100477	11	Q14739	1
Trans golgi network vesicle budding	0.2859502516296267	0.5172156960739245	0.6050055962554151	1.0	0.8712497280100477	29	O00443,Q9BXS5,P09496,O60749,P50570,Q14671,O00203,P02786,Q92538,P20645,Q00610	11
Signaling by notch1	0.3931373026761532	0.5160683481518232	0.605806673614895	1.0	0.8712497280100477	9	Q9UBN7	1
Dap12 interactions	0.446448456135483	0.5137236159999411	0.6074452383829771	1.0	0.8712497280100477	6	P62993	1
Rhov gtpase cycle	0.3313419437394037	0.5013653307223481	0.6161140346094522	1.0	0.8813585301779938	15	Q01082,P46940,Q13177,Q13813	4
Cellular response to chemical stress	0.2475424568996732	0.49742331484064	0.6188905676844538	1.0	0.8834840324921974	73	P09601,Q16881,O43242,P28070,P30519,Q15008,P51665,P13073,P49721,P28072,O00231,P28074,Q99436	13
Dual incision in gg ner	0.2944056229960266	0.4875883493054583	0.6258414495933704	1.0	0.8924759838472126	24	Q07864,P19447,Q92889,P56282,Q13620,P27694,P35244,P35251,P18074,P28340,P09874,Q9Y2S7	12
Notch1 intracellular domain regulates transcription	0.4213248892775367	0.4848524722832137	0.6277809982911722	1.0	0.8943102878882567	7	Q9UBN7	1
Activation of bh3 only proteins	0.3766261582395652	0.4821251158224401	0.6297170690042915	1.0	0.8959117914871485	10	Q04917,P62258,P31946,P27348,P63104	5
Interleukin 4 and interleukin 13 signaling	0.3571474419704665	0.4771844816785524	0.6332307605016281	1.0	0.8959117914871485	12	P09601,P07900	2
Apoptosis induced dna fragmentation	0.3752793278020342	0.47623600069386	0.6339062543379685	1.0	0.8959117914871485	10	P26583	1
Kinesins	0.3257748945174716	0.4722451514416761	0.6367518150198792	1.0	0.8959117914871485	15	P33176,Q9Y496,Q9H0B6,P52732,P04350	5
Rab regulation of trafficking	0.2696797891077441	0.4696361857707759	0.6386149670961911	1.0	0.8959117914871485	32	P20339,P31150,Q9UJY4,Q86SZ2,O43617,P62820,Q14C86,Q4KMP7,P62258,P60520,Q9Y3P9,Q8IUR0	12
Senescence associated secretory phenotype sasp	0.2987668616692423	0.4691845103105879	0.6389377563085294	1.0	0.8959117914871485	21	P11802,Q9UJX3,P27361,P30260,P40763,Q15418,Q16763,P24941	8
Rhoj gtpase cycle	0.3056329215601935	0.4683041563047393	0.6395670965929316	1.0	0.8959117914871485	19	Q13177,Q9Y6M7,O75323	3
Notch hlh transcription pathway	0.434278955162311	0.4682205974303283	0.6396268439697068	1.0	0.8959117914871485	6	Q9UBN7	1
Apc c cdc20 mediated degradation of cyclin b	0.3644510733658059	0.4679225665172867	0.6398399650289908	1.0	0.8959117914871485	11	Q9UJX3,Q16763,P06493,P30260	4
Rhod gtpase cycle	0.2929728367392341	0.467656178334529	0.6400304836190147	1.0	0.8959117914871485	23	O60610,Q14739,P50402,O15173,Q9Y6M7,Q68EM7	6
Negative regulation of mapk pathway	0.3446014429309781	0.4638011791152693	0.6427901984874373	1.0	0.8971534307520895	13	Q02750,Q99956,P30086,P31946,P27361,Q14738,P30153	7
Integrin cell surface interactions	0.5707164815127878	0.4616960307287286	0.6442993179202299	1.0	0.8971534307520895	3	Q08722	1
Energy dependent regulation of mtor by lkb1 ampk	0.4467801038552107	0.4600158517929307	0.6455048424330228	1.0	0.8971534307520895	5	Q15382	1
Dna damage bypass	0.2896491658517926	0.4571961613223924	0.6475300572306428	1.0	0.8974165784793761	24	Q07864,Q13620,P35244,P35251,P28340,P56282,Q9Y2S7	7
Glutathione synthesis and recycling	0.4459426024696153	0.4570693020334722	0.6476212341684879	1.0	0.8974165784793761	5	Q96KP4,O75223	2
Interaction between l1 and ankyrins	0.56858353038208	0.455191029526671	0.6489718135095561	1.0	0.8974165784793761	3	Q01082	1
Ddx58 ifih1 mediated induction of interferon alpha beta	0.3214382364558611	0.4500223934249036	0.6526942937902782	1.0	0.9016533685155308	15	P07900,Q13526,P09429,P08238,P61086,Q9UII4,Q13546	7
Activation of the ap 1 family of transcription factors	0.5640763462849261	0.4415702973775402	0.6588001816898983	1.0	0.9064450858498	3	P27361,Q16539	2
Erk mapk targets	0.3667350565595244	0.4395224329459417	0.6602830310290861	1.0	0.9064450858498	10	P27361,Q15418,Q14738,Q16539,P30153	5
Mapk targets nuclear events mediated by map kinases	0.3667350565595244	0.4395224329459417	0.6602830310290861	1.0	0.9064450858498	10	P27361,Q15418,Q14738,Q16539,P30153	5
Rhoa gtpase cycle	0.2599979365527595	0.4249672912410556	0.6708605190594716	1.0	0.9159265854699818	39	O60610,P46940,O15498,P30519,P49257,Q92974,Q14739,P52565,O15173,Q86VI3,Q9H2G2,Q86UP2	12
Ca dependent events	0.4030716723549494	0.4159229065051947	0.6774664171158828	1.0	0.920112140256128	7	P13861,P28482,Q13555,P17612,P52292,P10644	6
Late endosomal microautophagy	0.3857203263307351	0.4138987035585192	0.6789482933852757	1.0	0.9211895080717964	8	Q9UBN7	1
Signaling by erythropoietin	0.4326081788724196	0.411172711180192	0.6809458966071362	1.0	0.9229850816387816	5	P62993	1
Hsf1 dependent transactivation	0.3312606434578258	0.4019728985750156	0.6877039716720026	1.0	0.9303031000187466	13	P08238,P07900,P42345	3
Gap filling dna repair synthesis and ligation in gg ner	0.3073904529520502	0.4001394987112278	0.6890537732263182	1.0	0.93051550972223	16	Q07864,P35244,P35251,P28340,P56282,Q9Y2S7	6
Transcriptional regulation of granulopoiesis	0.4148952966363926	0.3991421787540902	0.6897884450131224	1.0	0.93051550972223	6	P11802,P40763	2
Glutathione conjugation	0.3299367830826248	0.3960389214017753	0.69207631558896	1.0	0.93051550972223	13	Q96KP4,Q9Y2Q3,O75223,P78417	4
Nef mediated cd4 down regulation	0.4135107471852599	0.3943825478417858	0.6932986266739771	1.0	0.93051550972223	6	P63010,O95782,O94973,P53680,Q9UI12	5
Nef mediated cd8 down regulation	0.4135107471852599	0.3943825478417858	0.6932986266739771	1.0	0.93051550972223	6	P63010,O95782,O94973,P53680,Q9UI12	5
Ret signaling	0.4251574021682246	0.3864082869953347	0.6991943137009149	1.0	0.9347627104067896	5	P62993	1
Apoptotic cleavage of cell adhesion proteins	0.4232448637294153	0.3801590805335235	0.7038273320070114	1.0	0.9366745829338342	5	Q07157	1
Response to elevated platelet cytosolic ca2	0.2684557226059604	0.3781937609797833	0.7052866599042855	1.0	0.937414987775696	28	Q9NUQ9,Q8NBX0,P07602	3
Gab1 signalosome	0.5406772995476954	0.3737603840490653	0.7085825957420155	1.0	0.9399705170259876	3	P62993	1
Cytochrome c mediated apoptotic response	0.540218132242662	0.3724811189022149	0.7095346672344807	1.0	0.9403223227918722	3	P28482,P27361	2
Enos activation	0.4188372540689679	0.3659299294856708	0.7144173624554873	1.0	0.9443197965391742	5	P07900	1
Polymerase switching on the c strand of the telomere	0.3137465212180226	0.3656578705528616	0.7146203865701859	1.0	0.9443197965391742	14	P49642,Q9NYB0,P35251,Q9Y2S7	4
Pyruvate metabolism	0.2994696610605443	0.3444278533712729	0.7305245448667499	1.0	0.9551939846442986	15	O95563,P21796,P35613,P53985	4
Dap12 signaling	0.494601225943555	0.3359453057347789	0.7369121114234409	1.0	0.9580251860138592	4	P62993	1
Beta catenin phosphorylation cascade	0.3799409352992339	0.3350486079053659	0.7375884193269595	1.0	0.9580251860138592	7	P30154,P48729,P25054,Q14738,P30153	5
Disassembly of the destruction complex and recruitment of axin to the membrane	0.3799409352992339	0.3350486079053659	0.7375884193269595	1.0	0.9580251860138592	7	P30154,P48729,P25054,Q14738,P30153	5
Signaling by ctnnb1 phospho site mutants	0.3799409352992339	0.3350486079053659	0.7375884193269595	1.0	0.9580251860138592	7	P30154,P48729,P25054,Q14738,P30153	5
Uptake and function of anthrax toxins	0.49048181675311	0.324715715447272	0.7453962394556517	1.0	0.9639952766631013	4	P45985,Q8WUM4	2
2 ltr circle formation	0.3905279701963505	0.3191545489820228	0.7496093206695733	1.0	0.9672150424096568	6	P49917	1
Rna polymerase iii transcription	0.3340205398006269	0.3107400205355947	0.755998270330287	1.0	0.9727083008291004	10	P05455,Q9NW08,O14802	3
Signal regulatory protein family interactions	0.5136477560021264	0.3021275426731316	0.7625548369292803	1.0	0.9780601392237732	3	P62993	1
Transcription coupled nucleotide excision repair tc ner	0.2403054224287276	0.301523272056614	0.7630155067136521	1.0	0.9780601392237732	44	Q9UBW8,Q99627,P19447,P23193,Q9BT78,Q13620,P35244,P35251,P61201,P18074,P28340,P56282,Q9Y2S7	13
Rsk activation	0.4799702159338959	0.2969415164173715	0.7665111593415541	1.0	0.9802926294148832	4	Q15418	1
Synthesis of pips at the early endosome membrane	0.4797700814054452	0.2964252602276368	0.7669053368176333	1.0	0.9802926294148832	4	Q13614,Q9BTU6	2
Pcna dependent long patch base excision repair	0.280711567110306	0.2943779565096673	0.7684691092074865	1.0	0.9804605876095516	17	Q07864,P35244,P35251,P28340,P56282,Q9Y2S7	6
Attenuation phase	0.3362890334596303	0.2931447119943576	0.7694115419174035	1.0	0.9807489766153868	9	P08238,P07900,Q02790,P0DMV9	4
Copii mediated vesicle transport	0.2485127209492923	0.288972105681241	0.7726027237875688	1.0	0.981295497008994	30	Q9Y6B6,P49755,O60763,Q12907,O94979,Q86SZ2,O15498,P62820,O43617,P49257,Q8IUR0,Q15363,Q15436	13
Signaling by fgfr in disease	0.2791064747970871	0.2873921680010463	0.7738120574108385	1.0	0.981295497008994	17	Q16630,P19174,P62993	3
Dna damage recognition in gg ner	0.2826917690579389	0.2866622323690396	0.7743709585894518	1.0	0.981295497008994	16	Q9UBW8,Q99627,P54727	3
Telomere c strand lagging strand synthesis	0.2672410808874882	0.283179399423622	0.7770393191850407	1.0	0.981295497008994	20	P49643,P51530,P27694,P35244,P35251,P49642,Q9NYB0,P28340,Q9Y2S7	9
Diseases of dna repair	0.3180249637114913	0.2806257930566544	0.7789974306725278	1.0	0.981295497008994	11	P52701,P43246,P20585	3
O linked glycosylation of mucins	0.5047716428084418	0.2803226767366318	0.7792299544228916	1.0	0.981295497008994	3	Q86SF2,O43505	2
O linked glycosylation	0.5047716428084418	0.2803226767366318	0.7792299544228916	1.0	0.981295497008994	3	Q86SF2,O43505	2
Aspartate and asparagine metabolism	0.3901586633255617	0.2796775566974615	0.7797248986112466	1.0	0.981295497008994	5	P17174	1
Amyloid fiber formation	0.3896681335913754	0.2783039613005225	0.7807790355162283	1.0	0.981295497008994	5	Q9UJY4	1
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	0.3456714462084204	0.2739254073994558	0.7841419458178736	1.0	0.9839508009392016	8	Q9C0C2,Q9UIV1	2
Sting mediated induction of host immune responses	0.373084436145763	0.2672536663400053	0.7892738585092598	1.0	0.9859973673537497	6	P12956,P13010	2
Irf3 mediated induction of type i ifn	0.373084436145763	0.2672536663400053	0.7892738585092598	1.0	0.9859973673537497	6	P12956,P13010	2
Rnd3 gtpase cycle	0.2890014431568569	0.2632102521188479	0.7923885292868698	1.0	0.9859973673537497	14	Q86UP2,Q07065	2
Scavenging by class f receptors	0.4661577565953932	0.2624490793593257	0.7929752384634612	1.0	0.9859973673537497	4	P07900	1
Formation of the early elongation complex	0.2798433038351484	0.2614803338611757	0.7937221134303352	1.0	0.9860304657768864	15	Q8WX92,P18615,P18074	3
Integration of provirus	0.3547758592306524	0.2566715323279298	0.7974323493712601	1.0	0.9897415106883544	7	P49917	1
Signaling by egfr	0.3103021603716045	0.2540051347097992	0.7994915912455416	1.0	0.9902759333857296	11	P19174,P62993	2
E3 ubiquitin ligases ubiquitinate target proteins	0.2863593684276179	0.2533043901182072	0.8000330038894208	1.0	0.9902759333857296	14	Q9GZS3,Q15819,P78527,P68036,O75150,P04439,Q5VTR2,Q6PD62	8
Map3k8 tpl2 dependent mapk1 3 activation	0.3780280295822774	0.2467814688953355	0.8050773526933692	1.0	0.993067481870522	5	Q02750,Q13616,P45985	3
Interleukin 15 signaling	0.4886925794593221	0.2431343974145806	0.8079012852677021	1.0	0.993067481870522	3	P62993	1
Meiotic recombination	0.30690590466528	0.2427600588988379	0.8081912784676852	1.0	0.993067481870522	11	P35244,P11802,P24941	3
Downstream signaling of activated fgfr2	0.3758114039064176	0.2410166297258623	0.8095422277337492	1.0	0.993067481870522	5	P62993	1
Downstream signaling of activated fgfr3	0.3758114039064176	0.2410166297258623	0.8095422277337492	1.0	0.993067481870522	5	P62993	1
Downstream signaling of activated fgfr4	0.3758114039064176	0.2410166297258623	0.8095422277337492	1.0	0.993067481870522	5	P62993	1
Downstream signaling of activated fgfr1	0.3758114039064176	0.2410166297258623	0.8095422277337492	1.0	0.993067481870522	5	P62993	1
Erks are inactivated	0.3486213792636685	0.2391919372958919	0.810956754344553	1.0	0.9935380043595824	7	P28482,P30154,P27361,Q14738,P30153	5
Tp53 regulates transcription of genes involved in g2 cell cycle arrest	0.3326281824736047	0.2346614550103043	0.8144715068404755	1.0	0.9950368196190766	8	P06493,Q99873,P14635	3
Ephb mediated forward signaling	0.3113772277152648	0.2344912498299582	0.8146036254751052	1.0	0.9950368196190766	10	O15144,P61586,Q92747,P59998,O15145	5
Sema4d mediated inhibition of cell attachment and migration	0.3403747870528034	0.2342617315896727	0.8147817931285499	1.0	0.9950368196190766	2	P61586	1
Phase ii conjugation of compounds	0.2448103065639769	0.2330095492075384	0.815753990647915	1.0	0.9953361971452724	27	Q96KP4,P78417	2
Rab gefs exchange gtp for gdp on rabs	0.2482709872254394	0.2297633214094783	0.8182756875160073	1.0	0.996078680221856	24	P20339,P31150,Q86SZ2,O43617,P62820,Q14C86,P62258,Q8IUR0	8
Translation	0.2035137431026695	0.2237765648665897	0.8229311660900052	1.0	0.996078680221856	214	P46778,P43307,Q9BYD3,Q9P2J5,P61254,P26641,P60866,P62081,P62280,Q9UI10,P23396,P39023,P09132,P54577,P46776,O75821,P11940,P46783,P62917,P62277,P20042,P49590,O76094,Q15629,P83881,P82933,Q04637,Q8TAE8,P61353,P62750,Q14152,P26640,P55010,P60228,O60841,P05387,P07814,P08865,Q9Y262,P18077,P62701,Q9Y285,P37108,P39019,P62899,P26373,Q9BRJ2,P13798,P62861,Q15056,Q9NP81,P42766,P61927,P61011,P05198,P62829,Q9Y3U8,P62847,O75822,P62495,P35268,P46782,P23588,P46779,P62241	65
Flt3 signaling in disease	0.3428931852112978	0.2235532215662389	0.8231049661754242	1.0	0.996078680221856	7	P62993	1
Lagging strand synthesis	0.2616442816819638	0.217265296040954	0.8280016008614965	1.0	0.996078680221856	17	P51530,P27694,P35244,P35251,P49642,P28340,Q9Y2S7	7
Mitotic telophase cytokinesis	0.3046829556120828	0.2142278346044328	0.8303693910337169	1.0	0.996078680221856	10	Q29RF7,Q9UQE7,Q14683,Q8N3U4	4
Prolonged erk activation events	0.3387225827174644	0.2125566284871473	0.8316728037690302	1.0	0.9961155453716556	7	P31946,P27361,Q9ULH0	3
Base excision repair ap site formation	0.3507335380416226	0.2080449166802521	0.8351938961212877	1.0	0.9982100580520084	6	P13051,P78549,P62805,Q9NYB0,P29372	5
Polymerase switching	0.2886787198612118	0.2079688617399082	0.8352532804991322	1.0	0.9982100580520084	12	P49642,P35251,Q9Y2S7	3
Interleukin 2 family signaling	0.4418086750034073	0.2075133035802265	0.8356090040376929	1.0	0.9982100580520084	4	P62993	1
Downregulation of erbb2 erbb3 signaling	0.3301533219761422	0.2056335903942878	0.8370771368775265	1.0	0.9990920665957574	2	P31751	1
Post chaperonin tubulin folding pathway	0.3013465878808808	0.2045352660369683	0.8379352361317391	1.0	0.9992450681745216	10	Q13885,P04350,Q9BTW9	3
Signaling by ntrk2 trkb	0.34599005906161	0.1965946073296996	0.8441447909860944	1.0	1.0	6	P62993	1
Hemostasis	0.1943390320314647	0.1730859838615059	0.8625838419287966	1.0	1.0	106	P14174,Q9Y496,P42785,Q9H4M9,P78310,Q08722,P62993,P19174,P41240,O43852,Q8NBX0,P07602,P18206,P35613,Q9H0B6,Q9NUQ9,P04350,P53985	18
Formation of tc ner pre incision complex	0.2311582611093191	0.1713322669451831	0.8639625102095476	1.0	1.0	27	Q9UBW8,Q99627,P19447,P23193,Q9BT78,Q13620,P61201,P18074	8
Estrogen dependent gene expression	0.2299056061496433	0.166204911932788	0.8679956940498184	1.0	1.0	27	Q99873,P07900,P50750,O14646,Q9UQE7,Q14683,Q02790,P08238,Q8N3U4	9
Polo like kinase mediated events	0.4197067848619144	0.1644624723673443	0.8693670871570971	1.0	1.0	4	P53350,P14635,Q09028	3
Tnf signaling	0.3295803480040927	0.1601097742356505	0.8727946017800297	1.0	1.0	6	O95429,Q96BN8,P63244,O14920,Q13546	5
Signaling by csf3 g csf	0.3146364072413602	0.155672212550469	0.8762914012745278	1.0	1.0	7	Q15370,P62993,P40763	3
Signaling by mras complex mutants	0.4107310022322084	0.1488777704736339	0.881650082304239	1.0	1.0	4	P62140	1
Early phase of hiv life cycle	0.2845934820711843	0.1465105825400746	0.8835183364050414	1.0	1.0	9	P49917	1
Transferrin endocytosis and recycling	0.2831284153005505	0.1432667565884621	0.8860795093553069	1.0	1.0	9	P38606,P61421,P21283,P02786,P21281,Q9UI12,Q93050,Q9Y487	8
Amino acids regulate mtorc1	0.2638106859807984	0.1401141959370939	0.8885697645021349	1.0	1.0	12	Q15382	1
Creb1 phosphorylation through the activation of adenylate cyclase	0.4335378323108253	0.1396963876231697	0.8888998806788333	1.0	1.0	3	P17612,P10644	2
Pka activation in glucagon signalling	0.4335378323108253	0.1396963876231697	0.8888998806788333	1.0	1.0	3	P17612,P10644	2
Pka mediated phosphorylation of creb	0.4335378323108253	0.1396963876231697	0.8888998806788333	1.0	1.0	3	P17612,P10644	2
Regulation of tnfr1 signaling	0.329467939972712	0.1390134286324158	0.8894395375684621	1.0	1.0	5	O14920,Q13546,Q96BN8,P63244	4
Tp53 regulates transcription of genes involved in g1 cell cycle arrest	0.3015332197614904	0.1380418257667017	0.8902073617707162	1.0	1.0	2	P24941	1
Signaling by kit in disease	0.3992790662200078	0.1305904352014877	0.8960993095300893	1.0	1.0	4	P62993	1
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants	0.3992790662200078	0.1305904352014877	0.8960993095300893	1.0	1.0	4	P62993	1
Antiviral mechanism by ifn stimulated genes	0.2096687773228478	0.1253647651152389	0.9002347813705422	1.0	1.0	50	Q8N1F7,P78344,P12270,Q04637,P19174,P61221,Q9BTX1	7
Signaling by erbb4	0.2856668760443219	0.1228750322420052	0.9022060571626032	1.0	1.0	8	P16949	1
Signaling by fgfr1	0.2732313685868224	0.1227028491361719	0.9023424076335882	1.0	1.0	9	P62993	1
Signaling by fgfr3	0.2732313685868224	0.1227028491361719	0.9023424076335882	1.0	1.0	9	P62993	1
Signaling by fgfr4	0.2732313685868224	0.1227028491361719	0.9023424076335882	1.0	1.0	9	P62993	1
Deadenylation dependent mrna decay	0.2098170593971468	0.1200217540721219	0.9044659152663396	1.0	1.0	36	Q9Y450,O75175,Q9Y2L1,Q04637,Q6PGP7,P62312,Q9C0C2,P23588,Q9UIV1	9
Cargo concentration in the er	0.2469541174905083	0.1165919072297042	0.9071834510799036	1.0	1.0	13	Q9Y6B6,Q12907,P49755,P49257,Q15363,Q15436	6
Signaling by ptk6	0.2519884917452181	0.1140875933536766	0.9091683570757276	1.0	1.0	12	P23246,Q96JJ3,P11802,P04150	4
Tbc rabgaps	0.2450269931258782	0.1125248781803621	0.9104072450712232	1.0	1.0	13	P20339,P60520,Q4KMP7,Q9UJY4	4
Downstream signal transduction	0.2793808828356234	0.1115421012253307	0.9111864819251174	1.0	1.0	8	P62993	1
Signaling by pdgf	0.2793808828356234	0.1115421012253307	0.9111864819251174	1.0	1.0	8	P62993	1
Cytosolic sensors of pathogen associated dna	0.2236796999519976	0.1109815654301756	0.9116309650722488	1.0	1.0	18	P12956,Q9NW08,Q13546	3
Toll like receptor tlr1 tlr2 cascade	0.2221355327753515	0.1073231484519494	0.9145326207924184	1.0	1.0	18	Q02750,P45985,P09429,P27361,Q14738,Q15418,Q13616,Q16539,P30153	9
Toll like receptor 9 tlr9 cascade	0.2221355327753515	0.1073231484519494	0.9145326207924184	1.0	1.0	18	Q02750,P45985,P09429,P27361,Q14738,Q15418,Q13616,Q16539,P30153	9
Rna polymerase iii transcription initiation from type 1 promoter	0.2623942271642993	0.1028569324440261	0.918076519271784	1.0	1.0	9	Q9NW08,O14802	2
Tp53 regulates transcription of cell death genes	0.4056783848977905	0.1019947861121303	0.9187608135820328	1.0	1.0	3	P49327	1
Synthesis of diphthamide eef2	0.4030914876405098	0.0989755755417742	0.9211576627598884	1.0	1.0	3	Q9H2P9	1
Camk iv mediated phosphorylation of creb	0.4025221540558869	0.0983217922658554	0.9216767742942203	1.0	1.0	3	Q13555,P52292	2
Flt3 signaling	0.2931305421610687	0.0966530436778804	0.9230019308809312	1.0	1.0	6	P62993	1
G2 m dna damage checkpoint	0.2022600798450328	0.0933282419497176	0.9256427961621808	1.0	1.0	34	Q04917,P14635,Q15819,P51530,O95714,P62258,P31946,P06493,P35244,P27348,O60921,P63104	12
Resolution of sister chromatid cohesion	0.2008187784875365	0.0914912814318424	0.9271022335916892	1.0	1.0	54	P14635,Q9UQE7,Q9Y6G9,Q9P258,O14980,P06493,Q29RF7,Q14683,Q13409,Q2NKX8,P04350,O43237,Q14204,Q14008,O75122,Q13885,Q9Y266,Q14738,Q8N3U4	19
Keratinization	0.2976517976337521	0.0900161481724163	0.9282743825377282	1.0	1.0	5	Q14126,P04632	2
Formation of the cornified envelope	0.2976517976337521	0.0900161481724163	0.9282743825377282	1.0	1.0	5	Q14126,P04632	2
Nucleotide excision repair	0.2003260201520895	0.0885574162009936	0.9294336520086476	1.0	1.0	51	Q9UBW8,Q99627,P19447,P23193,Q15819,Q9BT78,Q13620,P35244,P35251,P61201,P18074,P28340,P56282,Q9Y2S7,P54727	15
Signaling by wnt in cancer	0.2519531004247283	0.0863109077591409	0.9312192676977752	1.0	1.0	9	Q13363,P30154,P48729,P25054,Q14738,P30153	6
Suppression of phagosomal maturation	0.2818150801774122	0.0817697404158555	0.9348298191199462	1.0	1.0	6	P20339,P52294,Q14974,Q9UI12,Q9H267	5
Negative feedback regulation of mapk pathway	0.3603818615751772	0.0814881583290105	0.9350537418442592	1.0	1.0	4	Q02750,P28482,P27361	3
Metalloprotease dubs	0.2737262007832417	0.0724476854475356	0.9422456369667872	1.0	1.0	6	Q15018,O95630,O00487	3
Recognition and association of dna glycosylase with site containing an affected purine	0.350494374360719	0.0720352114716496	0.9425738859258116	1.0	1.0	4	Q9NYB0,P29372,P62805	3
Synthesis of udp n acetyl glucosamine	0.3755964553510453	0.0716461492188871	0.9428835126520432	1.0	1.0	3	Q16222,O95394	2
Homology directed repair	0.1946963522854685	0.07042770569979	0.943853240033989	1.0	1.0	40	Q07864,Q15819,Q9UNS1,Q92889,P51530,O95714,P27694,P35244,P35251,P28340,P56282,O60921,Q9Y2S7,P24941	14
Met activates ras signaling	0.2614465002071063	0.0602793660808046	0.9519331355392656	1.0	1.0	6	P62993	1
Raf independent mapk1 3 activation	0.2500453339832686	0.0589841509919013	0.952964731807504	1.0	1.0	7	P06493,Q99956	2
Apoptotic factor mediated response	0.3314012956017697	0.0569083284718581	0.9546182199055976	1.0	1.0	4	P28482,P27361,P42574	3
Tnfr1 induced nfkappab signaling pathway	0.329355608591881	0.0555163554822155	0.955727100253776	1.0	1.0	4	O14920,Q13546,P63244	3
Pre notch processing in golgi	0.3483299250170298	0.0523706553719751	0.9582333556402932	1.0	1.0	3	Q15363,P16615	2
Processing of smdt1	0.2036250807564046	0.0432039608718538	0.9655389477195035	1.0	1.0	11	Q10713	1
Translesion synthesis by polk	0.2187919516879858	0.0423289036259196	0.9662365041677364	1.0	1.0	8	P35251	1
Synthesis of pg	0.3190184049079698	0.0388062107202376	0.9690448931273424	1.0	1.0	3	Q8IV08,Q8N2A8	2
Small interfering rna sirna biogenesis	0.302317655078381	0.0336979297608494	0.9731180298480322	1.0	1.0	3	Q15631,Q9UPY3	2
Microrna mirna biogenesis	0.1899467799371472	0.033241733041115	0.9734818183438452	1.0	1.0	10	Q9HAV4	1
Dual incision in tc ner	0.1777786571927457	0.0321486821508089	0.974353480712156	1.0	1.0	34	Q07864,P19447,P23193,Q92889,Q13620,P35244,P35251,P18074,P28340,P56282,Q9Y2S7	11
Dna repair	0.1484759515206281	0.0280381715654721	0.9776317065980356	1.0	1.0	111	Q9UBW8,Q99627,P20585,P13010,P23193,P78527,Q9UNS1,P52292,Q9BT78,P27694,P18074,P28340,Q9Y2S7,P24941,P52701,Q99496,Q6P6C2,P49917,P51530,P35251,Q9NYB0,P09874,O60921,Q07864,P19447,Q15819,O95714,Q13620,P35244,Q8N9N2,Q92905,P56282,P54727,P43246,Q9NVI1,Q92889,Q9NX46,Q13426,P12956,Q13619,P61201	41
Maturation of sars cov 2 nucleoprotein	0.2018992538356105	0.0275007078447492	0.9780603752835996	1.0	1.0	5	P48729	1
Sars cov infections	0.1764064636354199	0.0274222942695681	0.978122916677834	1.0	1.0	53	P04150,P07900,Q16706,P48729,Q14839,Q13546,Q02790,Q99720,P08238	9
Interleukin 35 signalling	0.266189502385816	0.0272469160882868	0.9782627959534947	1.0	1.0	3	P42224,P40763	2
Interleukin 27 signaling	0.266189502385816	0.0272469160882868	0.9782627959534947	1.0	1.0	3	P42224,P40763	2
Dna double strand break repair	0.1757671474123137	0.0266504860187785	0.9787385055212684	1.0	1.0	54	P13010,Q9UNS1,P27694,P28340,Q9Y2S7,P24941,Q99496,P49917,P51530,P35251,O60921,Q07864,Q15819,O95714,P35244,P56282,Q92889,Q13426,P12956	19
Translesion synthesis by polh	0.1659608884007287	0.0260007160626107	0.979256767309768	1.0	1.0	11	P35251	1
Signalling to erks	0.1629612940481304	0.0258342318298796	0.9793895579022908	1.0	1.0	12	P31946,P62993	2
Rho gtpases activate formins	0.1666050094814399	0.0131056817120856	0.9895434782374212	1.0	1.0	51	O60610,O75122,Q13885,Q9Y6G9,Q14204,Q14008,P35080,Q14738,Q13409,Q9Y266,Q2NKX8,P04350,O43237	13
Mitotic spindle checkpoint	0.1631907758488039	0.0089101861078721	0.9928907941390936	1.0	1.0	48	Q9Y6G9,Q13409,Q9Y266,Q16763,O43237	5