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Transport of small molecules 0.4323012665594853 2.788968201314301 0.0052876256423384 0.9994300895674788 0.0856352244833889 171 O15118,Q8WTV0,P20618,P30519,Q01650,O75027,P28072,P60900,P11166,P21796,Q8N4V1,O00231,Q70HW3,Q9UBX3,Q9NWR8,Q9Y487,P28074,P28070,P53985,P16615,P02786,Q6PIU2,Q9HD20,Q9UBI6,P30825,Q9BPX6,P49721,P55011,P45880,P51790,Q93050,P51798,Q9Y6M7,P61916,Q13555,Q9UNS2,Q9H4I9,Q99436,Q8IYU8 39
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.7054526336307289 2.743230242451003 0.0060838011633934 0.9998155731195572 0.0941986355958395 20 Q02818,P07942,Q06481,Q8NBJ4,Q07065,O43493,Q9BTY2,P05067 8
Gpcr ligand binding 0.8594122578774266 2.7124911455369056 0.0066779565455972 0.9999205830388664 0.1000983060930476 10 P05067,P42892,P22466 3
Peptide ligand binding receptors 0.9103939791503914 2.6371915943172937 0.0083595601236099 0.9999927035918128 0.1152078367249948 8 P05067,P42892,P22466 3
Class a 1 rhodopsin like receptors 0.9103939791503914 2.6371915943172937 0.0083595601236099 0.9999927035918128 0.1152078367249948 8 P05067,P42892,P22466 3
N glycan antennae elongation 0.9689645701730294 2.5812851549829428 0.0098433238508726 0.9999991152443226 0.1320880314845667 2 O60512 1
Phase i functionalization of compounds 0.7543707537081208 2.495990938453758 0.0125605810144089 0.9999999815821572 0.149981852960188 14 P30837,P07099 2
Sema4d in semaphorin signaling 0.8703032120418729 2.470963015871251 0.0134749753795639 0.9999999950074586 0.1564865310122269 8 P35579,P35580,Q7Z406,Q13464,O75116 5
Metabolism of porphyrins 0.8017744117264131 2.4530339444912244 0.0141656970518169 0.9999999981390644 0.1609634447258874 10 P22830,Q7KZN9,P30519 3
Receptor type tyrosine protein phosphatases 0.9258445482010424 2.4033534788683393 0.0162454757701895 0.9999999999050664 0.1802352390566697 2 P10586 1
Epha mediated growth cone collapse 0.8820757727708988 2.3988798877239352 0.0164453081093425 0.9999999999286971 0.181026868172372 7 P35579,P35580,Q7Z406,Q13464,O75116 5
Rho gtpase cycle 0.404245519094672 2.3677562608438825 0.0178963215645293 0.999999999991094 0.1926237478717264 172 P78371,P84095,Q86VI3,P30519,Q96N67,P06753,Q13505,Q9Y5S2,Q9UQB8,Q92888,Q96JJ3,Q86UP2,P02786,Q07960,Q07065,Q14739,O75116,Q9BXS4,P67936,Q13813,P20700,P12814,Q9NZM3,O15173,Q96RU3,Q13464,O75976,P61201,Q96F07,Q7L576,P41440,P11274,Q14185,Q8NBN3,Q9Y6M7,P08670,Q01082,Q9BT78,O75955,Q96HY6,Q96DH6,Q9UEY8 42
Regulated proteolysis of p75ntr 0.9137599560560276 2.352894295592957 0.018627928624777 0.9999999999968836 0.1988390260023547 2 P78536 1
Glycerophospholipid biosynthesis 0.5531033864784949 2.3491205701987092 0.0188178122374707 0.9999999999976272 0.1993556198691445 35 Q8N2A8,Q9HCL2,Q8IV08,Q9NPH0,P35790,Q8NCC3 6
Sema4d induced cell migration and growth cone collapse 0.9095723660351348 2.3146130077827265 0.0206341203596873 0.9999999999998256 0.2053134252029987 6 P35579,Q7Z406,O75116,P35580 4
Sting mediated induction of host immune responses 0.907799790710515 2.307641176536473 0.0210191022994279 0.9999999999998996 0.2053134252029987 6 P19474 1
Trans golgi network vesicle budding 0.5235469312080557 2.296564553952842 0.0216436226521594 0.9999999999999593 0.2053134252029987 42 P11717,P20645,P51809,P02786,Q9Y5X1,P15586,O43493,O75976,Q99523,O14976,Q9H3P7,P05067 12
Rhoa gtpase cycle 0.483322104535842 2.249598224187769 0.0244744612896241 0.9999999999999992 0.2239254282927301 52 P41440,O15173,P02786,Q86VI3,Q86UP2,Q07960,Q13464,P30519,O75116,O75955,Q96HY6,Q92888,P11274,Q8NBN3 14
Interferon gamma signaling 0.7028863558819243 2.2326114312100387 0.0255745796157034 1.0 0.2295211812077193 14 P19474,O15344,P10321,Q13555,P30511,P29372 6
Sulfide oxidation to sulfate 0.8851963746223558 2.232608820691713 0.0255747519159772 1.0 0.2295211812077193 2 Q9UBX3 1
Cell surface interactions at the vascular wall 0.6215968879431166 2.22676535173719 0.0259629601747886 1.0 0.2315304486473237 19 Q92896,P53985,P14174 3
Neutrophil degranulation 0.3984419012949047 2.2055259083939607 0.0274172118039781 1.0 0.2412346160792687 184 P42785,P78371,P84095,P20618,P30519,P14174,Q8N2G8,P10253,P06280,P16278,P11717,O00231,Q8WVQ1,Q07065,O75787,P15586,Q92542,P10619,Q13813,O00754,P07602,O15078,Q13464,Q93050,P12956,Q7L576,P04066,O00584,P61916,O15260,Q9BTY2,P15291,O43681,Q99436,Q9NQX7 35
Dopamine neurotransmitter release cycle 0.877506179620982 2.1999829566830233 0.0278081042591282 1.0 0.2412346160792687 2 Q13136 1
Iron uptake and transport 0.6182737263675876 2.19092325910838 0.0284573462763764 1.0 0.2417160153361064 18 Q9Y487,P30519 2
Synthesis of pa 0.7421836129140272 2.176066427081571 0.0295502938703011 1.0 0.2449197886073785 10 Q8N2A8,Q9HCL2 2
Mitochondrial calcium ion transport 0.6096223989015555 2.15378469784025 0.0312570602831141 1.0 0.2463338937730985 19 P21796,Q9NWR8,Q9H4I9,P45880,Q9Y4W6,Q8IYU8,Q9BPX6,Q9H300 8
Egr2 and sox10 mediated initiation of schwann cell myelination 0.7921620588810574 2.1373143376178345 0.032572433478855 1.0 0.2463338937730985 8 Q9NR77,P07942,Q16850 3
G alpha i signalling events 0.5876553193783202 2.1365145357425654 0.0326374974611436 1.0 0.2463338937730985 25 P07602,P05067,P22466,O43865 4
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7033632514196295 2.088562473645937 0.0367471261755241 1.0 0.2601844260367511 12 P46379,P05067 2
Keratan sulfate biosynthesis 0.9442307692307694 2.0479833103329694 0.0405616347580397 1.0 0.278787040849161 3 P15291,O60512 2
Recruitment of mitotic centrosome proteins and complexes 0.5006947966400525 2.02733700739767 0.0426279592826801 1.0 0.2887636234866795 39 Q96CW5,O15078,O94927,Q14203,Q96CS2,Q9H6D7,O75935,O95684,Q9BSJ2,O43805,Q9UPN4 11
Akt phosphorylates targets in the nucleus 0.8338368580060412 2.012838639472091 0.0441316075126758 1.0 0.2933086555913221 2 P31751 1
Runx2 regulates genes involved in cell migration 0.8338368580060412 2.012838639472091 0.0441316075126758 1.0 0.2933086555913221 2 P31751 1
Interferon alpha beta signaling 0.6923349325110644 1.9832568378561 0.0473387479774429 1.0 0.3102339344196146 11 Q13325,P10321,P30511,P42224,P04439 5
Ptk6 regulates proteins involved in rna processing 0.8242241142543245 1.971230920819456 0.048697468648974 1.0 0.3147464831486443 2 P23246 1
Heme biosynthesis 0.8207927258683532 1.9588093666949096 0.0501351162381054 1.0 0.3181999044121194 6 P22830,Q7KZN9 2
Cation coupled chloride cotransporters 0.8170832188959074 1.94023066607398 0.052351663226561 1.0 0.324915137100924 2 P55011 1
Rhobtb1 gtpase cycle 0.5676692265264504 1.9079948812547851 0.0563918778670116 1.0 0.3381113017643377 20 P78371,P08670,Q13464,O75116,Q9BT78 5
Rac2 gtpase cycle 0.4806868487017958 1.8856555375987565 0.0593413881230964 1.0 0.3498410705667065 40 Q86XL3,Q13505,Q8TAA9,P02786,Q07960,Q14739,P42166,P49257,Q9Y6W5,Q9NSV4,O15173,Q96RT1,Q9Y2U8,Q7L576,P11274,Q14185,P46940,P50402,Q8IZP0,Q9Y512 20
Negative regulation of nmda receptor mediated neuronal transmission 0.7574882645266247 1.8761338420005471 0.0606369037182854 1.0 0.353047096442414 7 Q13555,Q14168,P07196 3
Rho gtpases activate ktn1 0.7558428377608186 1.8690367878234857 0.0616176963957766 1.0 0.3543646294761195 7 P84095,Q86UP2 2
Recruitment of numa to mitotic centrosomes 0.4716206297006283 1.8592067564136032 0.0629978375102615 1.0 0.3574814032111283 42 Q96CW5,O15078,O94927,Q14203,Q96CS2,Q9H6D7,O75935,O95684,Q9BSJ2,O43805,Q9UPN4 11
Regulation of innate immune responses to cytosolic dna 0.8689941366240787 1.849869225975036 0.0643324002987268 1.0 0.3619018049254475 4 P19474 1
Protein localization 0.4132753398318184 1.835698137465017 0.0664023135818063 1.0 0.3683498418770282 83 Q9NR77,P21796,P46379,P25705,Q13505,O75431,O43681,O15254,P05067 9
Mitotic prometaphase 0.3998058499234651 1.818806151931006 0.0689410095076343 1.0 0.3773159471879463 108 Q8NBT2,P06493,Q96EE3,Q6P1K2,Q8N3U4,Q8WVM7,Q9H6D7,O95347,Q9NTJ3,Q12834,P50748,Q9Y6D9,Q9NTI5,O60566,Q96CW5,Q9H3R5,P57740,Q14203,O75935,Q9NXR1,Q15021,O43805,O15078,Q13362,Q8NFH4,P55735,Q96EA4,Q29RF7,P49792,Q15691,Q9UQE7,O94927,Q96CS2,Q96IY1,Q9HC35,O95684,Q9BSJ2,Q2NKX8,Q9UPN4,Q9BV73,Q9BS16,Q14738 42
Aurka activation by tpx2 0.475172745102103 1.8163357064500785 0.0693188911238049 1.0 0.3773159471879463 39 O75330,O15078,O94927,Q14203,Q96CS2,Q9H6D7,O75935,O95684,O43805,Q9UPN4 10
Cytosolic sensors of pathogen associated dna 0.5532392135153372 1.8160833976077024 0.0693575800721633 1.0 0.3773159471879463 20 P12956,P19474 2
Endosomal vacuolar pathway 0.8200549189438319 1.800239209847666 0.0718228750461065 1.0 0.3847849085169736 5 Q9UIQ6,P30511,P10321 3
Synthesis of pe 0.8553112521690822 1.7967597739902184 0.0723737649694507 1.0 0.3854510941714627 4 P35790 1
Transport of inorganic cations anions and amino acids oligopeptides 0.644884852028397 1.7923462739663747 0.0730775151819647 1.0 0.3869804347150528 12 Q70HW3,P55011,Q9UBX3,Q01650,Q15758,P30825,Q9Y666,Q9Y6M7 8
Sphingolipid metabolism 0.5152798728166976 1.7907633318689682 0.073331281809027 1.0 0.3869804347150528 29 P16278,P07602,P10619,O43681,Q9NRA0,Q96G23,P06280 7
Response to elevated platelet cytosolic ca2 0.4732351449231141 1.778684228419079 0.0752915463193564 1.0 0.3914604751438125 38 Q9NUQ9,P12814,Q08380,P07602,Q06481,Q8NBX0,P05067 7
Hs gag degradation 0.8722527472527477 1.7728239929048424 0.076257876395632 1.0 0.3950270141229617 3 P16278,P54802 2
Constitutive signaling by aberrant pi3k in cancer 0.7751678798434339 1.7709516032061 0.0765687500529983 1.0 0.3951845011892845 6 P84095 1
Retrograde transport at the trans golgi network 0.5347903580773788 1.763057043348102 0.0778908692692306 1.0 0.3976385318853113 24 P11717,O60499,P20645,Q96CN9,Q8IWJ2,Q96JB2,O43493,O43752 8
Synthesis of pg 0.8449424120295955 1.7563685397907145 0.0790255010392619 1.0 0.3997945906855631 4 Q8N2A8 1
Mucopolysaccharidoses 0.8026388125343465 1.730340372010402 0.0835694804801168 1.0 0.4117111818058901 5 P16278,P08236,P15586,P54802 4
Glycosphingolipid metabolism 0.5433974932333315 1.728357751741559 0.0839241049865733 1.0 0.4120176443417485 18 P16278,P07602,O43681,P10619,P06280 5
Role of phospholipids in phagocytosis 0.8373377148272607 1.7266688160384007 0.084227159183809 1.0 0.4120696780902326 4 O43865 1
Rho gtpases activate rocks 0.6486497895824906 1.7237337012482574 0.0847559281013783 1.0 0.4132218086326715 10 P35579,Q7Z406,O75116,P35580 4
Transcriptional regulation by runx3 0.4556236092947974 1.72102697603961 0.0852459288923239 1.0 0.4141776338251188 42 P28070,P28074,P20618,P49721,Q13573,P28072,Q99436,P60900 8
Insulin receptor recycling 0.6463603989602489 1.712410802546923 0.0868209896906204 1.0 0.4179623405506146 10 Q9Y487 1
Extracellular matrix organization 0.4740185318419082 1.712039437594212 0.0868894008873888 1.0 0.4179623405506146 34 P07942,P12814,O75718,P05067,O15484,P78536,Q9BX67,Q92542,P55081,O14936 10
Signaling by notch4 0.4454278658926001 1.711901572091906 0.0869148089292619 1.0 0.4179623405506146 45 O00231,P28070,P28074,P20618,P49721,Q13573,P28072,Q99436,P60900 9
Ros and rns production in phagocytes 0.6707466879574591 1.7080320209773714 0.0876304011018394 1.0 0.4199701875935092 9 Q9Y487 1
Depolymerisation of the nuclear lamina 0.6937474284208482 1.699483021824801 0.0892282108975501 1.0 0.4233082463119468 8 P20700,P06493,Q9Y2U8,P02545,P42166 5
Establishment of sister chromatid cohesion 0.6916775510112076 1.690082597282644 0.0910121537631019 1.0 0.4260336367183076 8 Q9UQE7,Q8WVM7,Q8N3U4,Q29RF7,Q9NTI5 5
Diseases of carbohydrate metabolism 0.6397561372889564 1.6796865657797515 0.0930183149696657 1.0 0.4325505141658713 10 P16278,P15586,P08236,P10253,P54802,P13807 6
Anchoring of the basal body to the plasma membrane 0.4553240590172369 1.6711755590446122 0.0946870063503093 1.0 0.4333810450532794 40 Q15051,O15078,O94927,Q14203,Q96CS2,Q9H6D7,O75935,O95684,O43805,Q9UPN4 10
Traf6 mediated nf kb activation 0.750608305640588 1.6685765812671745 0.0952013232387958 1.0 0.4333810450532794 6 P05067 1
Ras activation upon ca2 influx through nmda receptor 0.7867572398725655 1.6662804832953022 0.0956575621089921 1.0 0.4333810450532794 5 Q13555,P07196 2
Long term potentiation 0.7867572398725655 1.6662804832953022 0.0956575621089921 1.0 0.4333810450532794 5 Q13555,P07196 2
Unblocking of nmda receptors glutamate binding and activation 0.7867572398725655 1.6662804832953022 0.0956575621089921 1.0 0.4333810450532794 5 Q13555,P07196 2
Ub specific processing proteases 0.3983319017778551 1.6599333914390728 0.0969278531007735 1.0 0.4349405892324521 80 P21796,P28070,P28074,P20618,P45880,Q14457,Q12834,P28072,Q99436,P60900,Q9UPT9,P49721 12
Striated muscle contraction 0.7465241823401433 1.651475229108511 0.098641574714533 1.0 0.4370628263294876 6 P08670,P67936,P09493 3
Lysosome vesicle biogenesis 0.529379951710361 1.639472221585634 0.1011149512926363 1.0 0.4398289345675676 18 P05067 1
Abc family proteins mediated transport 0.4145790090007246 1.6324014832070133 0.1025949368948637 1.0 0.4447885110303478 57 P28070,P28074,P20618,P49721,O75027,P28072,Q99436,P60900 8
Abc transporter disorders 0.4295990889714939 1.6270676406823188 0.1037227327324308 1.0 0.4464821840667416 47 P28070,P28074,P20618,O14678,P49721,P28072,Q99436,Q9NUN5,P60900 9
G beta gamma signalling through pi3kgamma 0.8340659340659343 1.6245768234870177 0.1042527588233526 1.0 0.4464821840667416 3 P31751,Q9UBI6 2
G protein beta gamma signalling 0.7764310312598505 1.6244771415482366 0.1042740150356162 1.0 0.4464821840667416 5 P31751,Q9UBI6 2
Uch proteinases 0.4220344431969196 1.620483852556671 0.105128380229033 1.0 0.4464821840667416 49 Q8NB78,Q99436,P28070,P28074,P20618,P49721,P28072,Q9H981,P60900 9
Muscle contraction 0.5018612430932673 1.6201328091172744 0.1052037509653358 1.0 0.4464821840667416 27 P08670,Q13555,P16615,O43865,P67936 5
N glycan antennae elongation in the medial trans golgi 0.8098073465729148 1.6186534844156086 0.1055218404346867 1.0 0.4464873068242449 4 P15291,O60512 2
Cd163 mediating an anti inflammatory response 0.8317624028361741 1.615593097128763 0.1061823173414779 1.0 0.4479367818387499 3 P78536 1
Antigen processing cross presentation 0.4121212034298975 1.598607608670995 0.1099078180486934 1.0 0.4588775282970145 56 Q9UIQ6,P28070,P28074,P30511,P20618,P49721,P28072,Q99436,P60900 9
Mrna editing 0.7388080197747844 1.5959365681429654 0.1105029561208377 1.0 0.459288097859175 2 P55265 1
Phospholipid metabolism 0.4145860684567736 1.5938665625186357 0.1109659250872918 1.0 0.4598558483764536 52 Q8N2A8,Q9HCL2,Q8IV08,Q9NPH0,P35790,Q8NCC3 6
Leishmania infection 0.4451023081201664 1.5837605710340084 0.1132482150837037 1.0 0.4679376394514328 40 P35579,Q96JJ3,Q96F07,O43865,P78536,Q9UQB8,P05067,Q14185 8
Keratan sulfate keratin metabolism 0.6676259809207372 1.580355398988831 0.1140254995439056 1.0 0.469771721805155 8 P16278,P15291,O60512,O43505 4
Rho gtpases activate cit 0.6403565751297481 1.5633375921457962 0.117973210665834 1.0 0.4813530025262612 9 P35579,Q7Z406,P35580 3
Synthesis of pc 0.6834359408160388 1.5524144933718829 0.1205630777606701 1.0 0.4830424991779874 7 P35790 1
Organelle biogenesis and maintenance 0.3762151984699837 1.534334403178277 0.1249474062241029 1.0 0.4960999896701757 110 P54619,P78371,Q9Y496,Q9H6D7,Q13505,Q9Y366,A6NIH7,Q14203,O00411,O75935,Q96RR1,O43805,O15078,P00846,O75431,O75964,P48735,Q9NX63,Q15051,O94927,Q96CS2,P25705,O95684,Q96RK4,Q9UPN4,A0AVF1 26
Sialic acid metabolism 0.7883895292179743 1.5341479670984184 0.1249932550269072 1.0 0.4960999896701757 4 P10619 1
Cdc42 gtpase cycle 0.4435320383350818 1.5304698240145735 0.1259004772586214 1.0 0.4965971011371589 38 P02786,Q86VI3,Q86UP2,Q07960,Q96RU3,Q96N67,Q9Y5S2,Q9UQB8,P11274 9
Signaling by notch1 pest domain mutants in cancer 0.6555150146691382 1.5247845838181242 0.1273128362975168 1.0 0.4965971011371589 8 P78536,Q13573 2
Anti inflammatory response favouring leishmania parasite infection 0.5847739868683602 1.523449844066754 0.1276461998733427 1.0 0.4965971011371589 13 P35579,P78536,O43865 3
Interleukin 1 signaling 0.4083002959660308 1.5223302987353666 0.1279263398960344 1.0 0.4965971011371589 50 P28070,P28074,P20618,P49721,P28072,Q99436,P60900,P05067 8
Signaling by vegf 0.4621169737824291 1.5197876130759944 0.1285643633058548 1.0 0.4965971011371589 32 P35221,Q96JJ3,Q13464,O75116,Q96F07,P31751,O43865,Q9Y6W5,Q7L576,Q9UQB8,Q14185 11
Nuclear signaling by erbb4 0.7815277201981253 1.5070007709145627 0.1318104595992677 1.0 0.5019484799334277 4 P78536,Q92542 2
Semaphorin interactions 0.5050379492601332 1.503699874732771 0.1326586615066369 1.0 0.5026757803609405 20 P35579,P35580,Q7Z406,Q13464,O75116 5
Deubiquitination 0.3801064986591763 1.4947549509485356 0.1349784072484066 1.0 0.5050165315266305 98 Q99436,P21796,Q8NB78,P28070,P28074,P20618,P45880,Q14457,Q12834,P28072,Q9H981,P60900,Q9UPT9,P49721 14
Protein protein interactions at synapses 0.5347532947235073 1.478471766351771 0.139281548722375 1.0 0.508687261711124 16 Q13136,Q14168,O75955,P10586,P41440 5
Slc mediated transmembrane transport 0.4812563951202303 1.47322049497986 0.1406915904720787 1.0 0.508687261711124 27 P11166,O00400,Q70HW3,P55011,Q9UBX3,P53985,Q8TB61,Q01650,Q15758,P30825,Q9Y666,Q9Y6M7 12
Ptk6 regulates cell cycle 0.7107937379840668 1.471204442464751 0.1412358361433638 1.0 0.508687261711124 2 P11802 1
Runx1 regulates expression of components of tight junctions 0.7096951386981564 1.4663034167091515 0.1425656450780796 1.0 0.508687261711124 2 Q16625 1
Transferrin endocytosis and recycling 0.5896181643036278 1.4647022691928713 0.1430021655731801 1.0 0.508687261711124 11 Q9Y487 1
Rac3 gtpase cycle 0.43570762121149 1.4644156864257838 0.1430804046742544 1.0 0.508687261711124 38 Q8TAA9,O15173,Q96RT1,P02786,Q7L576,Q96AC1,Q07960,Q9Y2U8,P50402,Q14739,Q8IZP0,P42166,P49257,Q15758,Q9Y6W5,Q9NSV4,Q9UQB8,P11274 18
Bile acid and bile salt metabolism 0.6630989287022068 1.4621912534852473 0.1436888077792955 1.0 0.508687261711124 7 Q9H4L5 1
Synthesis of bile acids and bile salts 0.6630989287022068 1.4621912534852473 0.1436888077792955 1.0 0.508687261711124 7 Q9H4L5 1
Signaling by notch 0.3889877961812142 1.4599059284750031 0.1443159296740999 1.0 0.5096269296010194 65 O00231,P28070,P28074,P16615,P20618,P15291,P49721,Q13573,P28072,P78536,Q99436,P60900 12
Defects in cobalamin b12 metabolism 0.6997986488424472 1.454496081970679 0.1458088189480872 1.0 0.5110939195826233 6 O14678,Q9NUN5 2
Rac1 gtpase cycle 0.4025952610446692 1.4343441081449102 0.1514740889994001 1.0 0.5151115390747943 49 Q86VI3,Q96N67,Q9UQB8,Q8TAA9,P02786,Q86UP2,Q07960,A1A4S6,Q14739,P42166,Q15758,Q9Y6W5,Q9NSV4,Q96RT1,Q9Y2U8,Q96F07,Q16513,Q7L576,P11274,Q14185,P46940,Q96AC1,P50402 23
Pyruvate metabolism 0.4972549461433415 1.4334911366819336 0.1517175300685638 1.0 0.5151115390747943 18 P21796,P53985 2
Interleukin 1 family signaling 0.3976497455412544 1.4327082048049409 0.1519412437509828 1.0 0.5151115390747943 53 P28070,P28074,P20618,P49721,P28072,Q99436,P60900,P05067 8
Cobalamin cbl vitamin b12 transport and metabolism 0.655969918465476 1.4304632579957646 0.1525841038476008 1.0 0.5151115390747943 7 O14678,Q9NUN5 2
Regulation of runx3 expression and activity 0.43168539375335 1.430369180991426 0.152611088735699 1.0 0.5151115390747943 38 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Vitamin d calciferol metabolism 0.761747732893653 1.4285856309837053 0.1531233665080429 1.0 0.5151115390747943 4 Q99538,P04062,P61956 3
Synthesis of pips at the er membrane 0.7006316945893947 1.4258514283420645 0.1539112322824471 1.0 0.5163355387761145 2 P42356 1
Sphingolipid de novo biosynthesis 0.5815293257623171 1.4229959595544683 0.1547373265351646 1.0 0.5166466660854192 11 Q96G23,Q9NRA0,P27544,O95470 4
Signaling by ptk6 0.5720276768120638 1.4121630810316927 0.1579019483309243 1.0 0.5234914004665231 12 Q96JJ3,Q14185,P23246,P31749 4
Fcgamma receptor fcgr dependent phagocytosis 0.452515526834454 1.40295424345143 0.1606304839175389 1.0 0.5306070792387101 31 P35579,Q8IV08,Q96JJ3,Q96F07,O43865,Q9UQB8,Q14185 7
Hedgehog ligand biogenesis 0.4163533305838872 1.3986059266142614 0.1619311881282081 1.0 0.5306070792387101 43 P28070,P28074,P20618,P49721,P28072,P78536,Q99436,P60900 8
P38mapk events 0.6912936006591556 1.3841487243057615 0.1663129201595241 1.0 0.5387009298960219 2 P11233 1
Apoptotic cleavage of cellular proteins 0.4874453546782576 1.378322051647293 0.1681038777488823 1.0 0.5420099856937649 19 P20700,P49354,P08670,P02545,Q13813 5
Ptk6 regulates rho gtpases ras gtpase and map kinases 0.7481473453302415 1.3745635390460291 0.1692667989121492 1.0 0.543273165528971 4 Q14185 1
Rho gtpases activate paks 0.5637130486144935 1.3681768831969845 0.1712567156671252 1.0 0.5471671482425836 12 P35579,P35580 2
Flt3 signaling 0.7118926763273399 1.3611058680081356 0.1734802355260993 1.0 0.5500030935634845 5 P31751 1
Scf skp2 mediated degradation of p27 p21 0.4141937487992558 1.3570102248163545 0.1747779616859388 1.0 0.5500030935634845 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Degradation of axin 0.4229284073509924 1.356058835164719 0.1750804490244601 1.0 0.5500030935634845 38 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Cross presentation of soluble exogenous antigens endosomes 0.4229284073509924 1.356058835164719 0.1750804490244601 1.0 0.5500030935634845 38 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Ecm proteoglycans 0.6764449758842264 1.3553394645904489 0.1753094268575656 1.0 0.5500030935634845 6 P05067 1
Degradation of dvl 0.4183754061395408 1.353043323720051 0.1760417902106423 1.0 0.5500030935634845 40 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Amino acid transport across the plasma membrane 0.7098254234071115 1.3526282336772435 0.1761744279699977 1.0 0.5500030935634845 5 P30825 1
Synaptic adhesion like molecules 0.6380992795989883 1.3507467649276974 0.1767765663114737 1.0 0.5500030935634845 7 P41440,P10586 2
Cristae formation 0.4801444817708108 1.3502671116171472 0.1769303178223298 1.0 0.5500030935634845 21 P00846,Q13505,O75431,O75964 4
Asymmetric localization of pcp proteins 0.4178120172000624 1.3481528321259333 0.1776092317752913 1.0 0.5500030935634845 40 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Regulation of ras by gaps 0.4194880012154608 1.3441067667422866 0.1789138642616921 1.0 0.5528281463700091 39 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Miscellaneous transport and binding events 0.6124389028637427 1.3257966473907836 0.1849070638183945 1.0 0.5607944737673562 8 Q9UNS2,Q8N4V1,Q9HD23,Q9UEY8 4
Rhobtb gtpase cycle 0.4462305734244962 1.3167175597412364 0.1879333153947016 1.0 0.5648036813435443 30 P12814,P78371,P08670,Q13464,P61201,O75116,Q9BT78 7
Sulfur amino acid metabolism 0.5536492599861192 1.314827988450201 0.1885677187833467 1.0 0.5653019484377354 12 P32929,Q13126,Q9UBX3 3
Signaling by erbb4 0.628704702716328 1.3087593464295686 0.1906158817973287 1.0 0.5696772966939541 7 P78536,Q92542 2
Glycosaminoglycan metabolism 0.4727373110966191 1.300734329801189 0.1933494071588457 1.0 0.5728352077329196 21 P16278,Q8NCH0,O75330,Q96L58,P15586,O43505,P15291,P08236,O60512,P54802 10
Mitotic g2 g2 m phases 0.3648623281963331 1.3002365299104115 0.1935199140389423 1.0 0.5728352077329196 97 P20618,Q9H6D7,P28072,Q9UL46,P60900,O00231,O75330,Q96CW5,P28070,P28074,Q14203,O75935,O43805,P49721,O15078,O94927,Q96CS2,O95684,Q9BSJ2,Q99436,Q9UPN4 21
Assembly and cell surface presentation of nmda receptors 0.5568140736122038 1.2950636584836963 0.1952982702530188 1.0 0.5768873433679319 11 Q13555,Q14168,P07196 3
Regulation of tp53 activity through association with co factors 0.7496464839756442 1.293477410685889 0.1958459919142847 1.0 0.5772949845339481 3 P31751 1
Clec7a dectin 1 signaling 0.384303995056532 1.2913500802924702 0.1965823122517709 1.0 0.5782556951205537 51 P28070,P28074,P20618,P49721,O43865,P28072,Q99436,P60900 8
Biological oxidations 0.3904435705410201 1.2877862112060592 0.1978203934665106 1.0 0.580685279988153 48 Q16850,P30837,Q9NX62,P07099,Q6N069 5
Auf1 hnrnp d0 binds and destabilizes mrna 0.4057952849669197 1.2824168856323062 0.1996964439196507 1.0 0.5825513239809271 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Myogenesis 0.6576103249257903 1.275182586015459 0.2022446234667754 1.0 0.5851389619398081 6 P19022,P35222,Q16539,P35221 4
Negative regulation of notch4 signaling 0.4046948643687307 1.272630765799501 0.2031490959665411 1.0 0.5865513856902798 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Purine salvage 0.6193052684406963 1.2667145154979325 0.2052573878505827 1.0 0.588764983910554 7 P00813 1
Cdt1 association with the cdc6 orc origin complex 0.4037435536908513 1.2641687440226592 0.206169466812456 1.0 0.588764983910554 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Dag and ip3 signaling 0.5990064340884997 1.2634627495805208 0.2064229255158365 1.0 0.588764983910554 8 O43865 1
Class i mhc mediated antigen processing presentation 0.3423097744820485 1.2611885963846992 0.2072409062331697 1.0 0.5899039128940124 126 P19474,P52888,Q9UIQ6,P28070,P28074,P55735,P30511,P20618,Q9NZ08,Q12834,P28072,Q99436,P60900,Q13049,P49721,P55786 16
Transcriptional regulation by runx1 0.3624831549962155 1.257191137192634 0.2086844318037126 1.0 0.5902104267109028 72 Q9HCL2,P28070,P28074,P20618,P49721,P28072,Q99436,P60900 8
Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.4564200643956041 1.2416195215936383 0.2143769756460807 1.0 0.5981329874956984 25 P14174 1
Rhog gtpase cycle 0.4048954083785452 1.2358238580295011 0.2165240446530254 1.0 0.6018243895728522 40 Q86XL3,Q8TAA9,O15173,Q96RT1,P84095,P02786,Q86UP2,Q96JJ3,Q07960,Q9Y2U8,Q14739,P50402,P42166,P49257,Q7L576,Q14185 16
Signaling by cytosolic fgfr1 fusion mutants 0.5707883067141906 1.2274841426805767 0.2196406782443656 1.0 0.6018243895728522 9 P11274,Q9UBW7 2
Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.6779462699441419 1.2218093183327672 0.2217797438945545 1.0 0.6018243895728522 5 Q8NB78,Q9HCE1 2
Processing of smdt1 0.5172706916899845 1.22176498937454 0.2217965117698459 1.0 0.6018243895728522 14 Q9NWR8,Q9H4I9,Q9Y4W6,Q9BPX6,Q9H300,Q8IYU8 6
Cilium assembly 0.3598231001580724 1.22135556273089 0.2219514244567089 1.0 0.6018243895728522 74 Q15051,P78371,Q9Y496,O15078,O94927,A6NIH7,Q14203,Q9H6D7,Q96CS2,O75935,O95684,Q96RK4,Q9Y366,O43805,Q9UPN4,A0AVF1 16
Initiation of nuclear envelope ne reformation 0.4917673432017568 1.2203142247166936 0.2223457794366521 1.0 0.6018243895728522 16 P20700,Q86XL3,P06493,Q9Y2U8,Q14739,P02545,P42166 7
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3764994170929603 1.217730203688732 0.223326515334302 1.0 0.6018243895728522 52 P28070,P28074,P20618,P49721,Q12834,P28072,Q99436,P60900 8
Cardiac conduction 0.5416437287889481 1.2162856531661144 0.2238761248394396 1.0 0.6018243895728522 11 Q13555,O43865 2
Ion homeostasis 0.5416437287889481 1.2162856531661144 0.2238761248394396 1.0 0.6018243895728522 11 Q13555,O43865 2
Rhob gtpase cycle 0.441144324092714 1.2126920160675714 0.2252475934541902 1.0 0.6018243895728522 28 P41440,Q86VI3,Q07960,Q13464,O75116,O75955,Q92888,P11274 8
Diseases of signal transduction by growth factor receptors and second messengers 0.3217615829092076 1.211969717327694 0.2255239728136735 1.0 0.6018243895728522 153 P26038,Q9P2E9,P51114,P84095,P20618,P02545,P06753,O00291,P28072,P60900,P35579,O00231,P28070,P28074,Q14203,P67936,Q92542,P49721,P33176,P48729,Q9NRY5,Q8IWJ2,Q13573,P78536,P11274,Q96PU8,Q13555,Q9NWH9,Q6WCQ1,Q01082,P31751,O95684,Q99436,Q9UBW7 34
Golgi associated vesicle biogenesis 0.4171875388706277 1.2070287426309845 0.2274210749743566 1.0 0.6056420085340792 33 P11717,P51809,P02786,Q9Y5X1,O75976,O43493,Q99523,O14976,Q9H3P7 9
Regulation of plk1 activity at g2 m transition 0.3971955326802331 1.2058827019571765 0.2278627212834099 1.0 0.6056420085340792 42 O15078,O94927,Q14203,Q96CS2,Q9H6D7,O75935,O95684,O43805,Q9UPN4 9
Stabilization of p53 0.3991151587712179 1.2035532492190502 0.2287622983183517 1.0 0.6056420085340792 41 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Mitochondrial biogenesis 0.408241187411757 1.2019048075434453 0.2294004115978549 1.0 0.6056420085340792 36 P00846,P25705,O00411,Q13505,O75431,O75964,Q96RR1,P48735 8
Rhoh gtpase cycle 0.4497642665207832 1.1949507113843394 0.2321062879652737 1.0 0.6096380748705109 25 P27105,P02786,Q13464,O75116,Q9BXS4,Q15758,Q9Y6M7 7
Metabolism of polyamines 0.399956227231313 1.192794681044436 0.2329497937218505 1.0 0.6099951145601871 40 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
G1 s dna damage checkpoints 0.3950691743662881 1.1869437558337588 0.2352498064717278 1.0 0.6119891329199174 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.6010456875373341 1.1850012226397733 0.2360169634985816 1.0 0.6119891329199174 7 Q5KU26,P30511,P10321 3
Antigen processing ubiquitination proteasome degradation 0.35493549666787 1.1803318576698496 0.2378682522494368 1.0 0.6138395007682353 98 P19474,P52888,Q9UIQ6,P28070,P28074,P20618,Q12834,P28072,Q99436,P60900,Q13049,P49721,P55786 13
Cyclin a cdk2 associated events at s phase entry 0.3869932485982776 1.178056240216128 0.2387741859560623 1.0 0.6150508738795099 45 O00231,P28070,P28074,P20618,P49721,P28072,Q99436,P60900 8
Interaction between l1 and ankyrins 0.6983487726092241 1.1766076625837092 0.2393521379617231 1.0 0.6151096101550397 4 Q13813 1
N glycan trimming and elongation in the cis golgi 0.6981482489335331 1.1758117659535792 0.2396701036019282 1.0 0.6151096101550397 4 O60476 1
Regulation of runx2 expression and activity 0.3885732158414541 1.1699946308999845 0.2420031295200937 1.0 0.6181396808981735 44 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Regulation of pten stability and activity 0.3860069741387525 1.1689593351885448 0.2424200155326585 1.0 0.6181396808981735 45 O00231,P28070,P28074,P20618,P31751,P49721,P28072,Q99436,P60900 9
Tnfr2 non canonical nf kb pathway 0.3899805348719883 1.161508442131581 0.2454351920230606 1.0 0.6181396808981735 43 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Dectin 1 mediated noncanonical nf kb signaling 0.3899805348719883 1.161508442131581 0.2454351920230606 1.0 0.6181396808981735 43 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Fc epsilon receptor fceri signaling 0.3693824471326972 1.1597391906103025 0.2461550088249797 1.0 0.6181396808981735 55 P28070,P28074,P20618,P49721,O43865,P28072,Q99436,P60900 8
Signaling by the b cell receptor bcr 0.3770289725021871 1.159470222970194 0.2462645672737706 1.0 0.6181396808981735 48 P28070,P28074,P20618,P49721,O43865,P28072,Q99436,P60900 8
C type lectin receptors clrs 0.3696538598559272 1.157570881213454 0.2470391979936257 1.0 0.6181396808981735 54 P28070,P28074,P20618,P49721,O43865,P28072,Q99436,P60900 8
Ion transport by p type atpases 0.5299552462229105 1.1555382860021393 0.247870063667472 1.0 0.6181396808981735 11 Q13555,P16615 2
Mitochondrial protein import 0.3985240542874841 1.1480613211523996 0.2509432501188089 1.0 0.6232135980452779 38 P21796,Q13505,O75431 3
Mapk6 mapk4 signaling 0.3729216435130343 1.147363065119281 0.2512315994958962 1.0 0.6232135980452779 49 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Rhoc gtpase cycle 0.4005929274354854 1.137918169929306 0.2551546533579243 1.0 0.6262054432761311 36 P46940,P27105,Q8TAA9,P41440,Q96RT1,P02786,Q86VI3,Q07960,Q13464,Q14739,O75116,P42166,P49257,O75955,Q16513,Q92888,P11274 17
Basigin interactions 0.5717596419884149 1.136941593345658 0.2555627028475391 1.0 0.6262054432761311 8 P53985 1
Interleukin 9 signaling 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.6262054432761311 2 P42224 1
Interleukin 21 signaling 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.6262054432761311 2 P42224 1
Interleukin 7 signaling 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.6262054432761311 2 P51532 1
Cytoprotection by hmox1 0.351799456984125 1.1347070183366792 0.2564980957122733 1.0 0.6263532354568339 72 P28070,P28074,P20618,P30519,P49721,P28072,Q99436,P60900 8
Disorders of transmembrane transporters 0.3532801908744138 1.1328128865438434 0.2572928386637203 1.0 0.6272069371577542 82 P11166,O00231,P28070,P28074,P55735,P53985,P20618,O14678,P28072,Q99436,P60900,Q9NUN5,P49721 13
Downregulation of erbb2 erbb3 signaling 0.7074175824175832 1.1277641274166883 0.2594195469595324 1.0 0.6278641790604144 3 P31751,P31749 2
Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.6336171381488547 1.12704114526228 0.2597250851682369 1.0 0.6278641790604144 2 P24941 1
Cd28 co stimulation 0.5696101271412796 1.1269677449445454 0.2597561186724582 1.0 0.6278641790604144 8 P42345,P62993,P31751,P63000,Q16512,P31749 6
Cellular response to chemical stress 0.3526499709983194 1.1253550368871654 0.2604386162689356 1.0 0.6283527574022779 82 Q99436,P28070,P28074,P20618,P30519,P28072,P00390,P60900,P49721 9
G protein mediated events 0.516282433456632 1.1161788670886896 0.2643455785032487 1.0 0.6308242069956337 12 O43865 1
Loss of mecp2 binding ability to the ncor smrt complex 0.6308706399340782 1.1148667033004371 0.2649075470732489 1.0 0.6308242069956337 2 Q9BZK7 1
Degradation of cysteine and homocysteine 0.6193533654117018 1.112380528377981 0.2659745730140819 1.0 0.6308242069956337 6 P32929,Q9UBX3 2
Nr1h2 and nr1h3 mediated signaling 0.5845838763055293 1.1113946813919733 0.2663985006581688 1.0 0.6308242069956337 7 Q8NB78,Q9HCE1 2
Ctla4 inhibitory signaling 0.5647898614649776 1.104611279920095 0.2693280612685365 1.0 0.6356503154562276 8 P31751,P31749,Q13362 3
Defective cftr causes cystic fibrosis 0.3812741075461728 1.103457208955422 0.269828664479272 1.0 0.635766869985442 44 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Glycogen storage diseases 0.7004968725163168 1.10072229430335 0.2710175401351231 1.0 0.6364395234173141 3 P10253 1
Intra golgi and retrograde golgi to er traffic 0.3438748094092652 1.093811976805795 0.2740374502091349 1.0 0.6418468769461703 108 Q92538,Q9Y496,Q15102,Q8TD16,O43493,O60476,A2RRP1,P11717,P20645,Q10472,Q14203,O75935,P24390,P33176,O60499,O00461,Q8IWJ2,Q96JB2,P52732,Q9Y678,O43752,Q96CN9,P35606,O15260,Q8TBA6 25
Fgfr1 mutant receptor activation 0.5179894259215363 1.093370314188644 0.2742312419599677 1.0 0.6418468769461703 11 P11274,Q9UBW7 2
Interleukin 12 family signaling 0.4157372454828029 1.0847774220483355 0.2780202476772224 1.0 0.6423489094413377 30 P14174 1
Interleukin 12 signaling 0.4268562203827433 1.0807062887596106 0.2798277848011308 1.0 0.6423489094413377 27 P14174 1
Cd28 dependent pi3k akt signaling 0.695138958330602 1.07982195862421 0.2802214708705524 1.0 0.6423489094413377 3 P31751 1
Pcp ce pathway 0.3627067658404216 1.0779435485049866 0.2810589494530746 1.0 0.6423489094413377 51 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Notch3 activation and transmission of signal to the nucleus 0.6940954752433972 1.0757554117467747 0.2820366583194875 1.0 0.6423489094413377 3 Q92542 1
Degradation of gli1 by the proteasome 0.3821772886422747 1.072095011018507 0.2836773594730706 1.0 0.6423489094413377 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Plasma lipoprotein clearance 0.4671957024489656 1.0720146470637972 0.2837134533638421 1.0 0.6423489094413377 16 Q8WTV0,O15118,P61916 3
Antigen presentation folding assembly and peptide loading of class i mhc 0.4406532585408431 1.0710154877841065 0.2841624658017574 1.0 0.6423489094413377 19 P55735,Q9NZ08,P30511,P10321 4
The role of gtse1 in g2 m progression after g2 checkpoint 0.3650185270625462 1.0707192438233686 0.2842956873471025 1.0 0.6423489094413377 49 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Downstream signaling events of b cell receptor bcr 0.3752070213317738 1.0693445231961236 0.2849144553148086 1.0 0.6423489094413377 45 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Signaling by notch3 0.6087670035931815 1.067463855748814 0.2857624267329037 1.0 0.6423489094413377 6 Q9Y6A5,Q92542,Q13573 3
Metabolism of steroids 0.3600101965403084 1.060432833334936 0.2889477316199744 1.0 0.6452097525396894 54 Q16850,Q15392,Q9HCL2,Q9BWD1 4
Tnf signaling 0.5356589876247528 1.0571088993946662 0.2904618901100653 1.0 0.6467102067552618 9 Q8TCT8 1
Runx1 regulates transcription of genes involved in differentiation of hscs 0.3797078316229652 1.0501082082430817 0.2936683652929437 1.0 0.6485559979588679 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Tryptophan catabolism 0.686158819504952 1.0448714099516765 0.2960824050861368 1.0 0.6493795008570775 3 Q01650 1
Innate immune system 0.359912243877256 1.0446659556923947 0.2961773846046542 1.0 0.6493795008570775 303 P42785,P84095,P20618,P30519,P14174,P10253,P28072,Q9UQB8,P05067,P06280,P60900,P16278,P11717,P35579,O00231,P19474,Q9Y487,P28074,P28070,Q96JJ3,Q07065,O75787,O43865,Q92542,P10619,P49721,Q13049,Q13813,P07602,Q8IV08,O15078,Q13464,Q96F07,Q93050,P12956,Q7L576,Q14185,P04066,Q15075,O00584,O15260,Q9BTY2,P15291,O43681,Q99436,Q9NQX7 46
Orc1 removal from chromatin 0.3588101907645629 1.041802677792336 0.297503172399836 1.0 0.6493795008570775 52 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Rhoj gtpase cycle 0.421018091122652 1.0384871930235398 0.299043294639095 1.0 0.6512395705509815 27 P27105,P02786,Q86VI3,Q07960,Q96RU3,Q9Y5S2,Q9Y6M7 7
Disassembly of the destruction complex and recruitment of axin to the membrane 0.53103767566377 1.0347555044831882 0.3007831075818612 1.0 0.6530098591415139 9 P48729,P35222,Q13362 3
Fceri mediated nf kb activation 0.3682031232672719 1.02665119083368 0.3045847401276598 1.0 0.6588965941891733 46 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Beta catenin phosphorylation cascade 0.5475888543326376 1.024995871760869 0.3053651355610576 1.0 0.6588965941891733 8 P48729,P35222,Q13362 3
Signaling by ctnnb1 phospho site mutants 0.5475888543326376 1.024995871760869 0.3053651355610576 1.0 0.6588965941891733 8 P48729,P35222,Q13362 3
Caspase mediated cleavage of cytoskeletal proteins 0.6274837902592818 1.0155213830046124 0.3098573589203706 1.0 0.6655320407298814 5 P08670 1
Cytosolic iron sulfur cluster assembly 0.559479247161421 0.9995564167533284 0.3175252237937109 1.0 0.6739308347990902 7 O75027 1
Interleukin 15 signaling 0.6045042570722265 0.9986578302669502 0.3179604753190546 1.0 0.6739308347990902 2 P40763 1
Ripk1 mediated regulated necrosis 0.4976688300353443 0.9880499069628412 0.3231282069415129 1.0 0.6812403109903161 11 P41440 1
Hedgehog on state 0.3685080186711754 0.9872098334904158 0.3235397820888575 1.0 0.6812403109903161 44 O00231,Q9Y496,P28070,P28074,P20618,P49721,P28072,Q99436,P60900 9
Sensory processing of sound by outer hair cells of the cochlea 0.4744250800649578 0.9807984051408428 0.3266921649071925 1.0 0.6834652013167629 14 P35579,Q01082,Q13813,O14936 4
Hemostasis 0.3052081786378821 0.9738349892682824 0.3301384771135969 1.0 0.689133502597123 142 Q9NUQ9,P12814,P42785,P07602,Q08380,Q06481,Q92896,P84095,Q8NBX0,P53985,P16615,P52732,P14174,Q01650,P05067,Q14185,P33176 17
Heparan sulfate heparin hs gag metabolism 0.551993155191936 0.9663711422529844 0.3338584988021575 1.0 0.6948399184818906 7 P16278,Q96L58,P54802 3
Nucleotide salvage 0.4981584273874748 0.9649113052185764 0.3345892384541398 1.0 0.6953336828641342 10 P00813 1
Pi3k akt signaling in cancer 0.478914266890346 0.9487455153395687 0.3427500588086931 1.0 0.7023742093337724 13 P84095,P31751,Q9NWH9 3
Meiotic synapsis 0.4466522356774517 0.9483403678604309 0.3429562065159732 1.0 0.7023742093337724 16 P20700,Q9UQE7,Q9UH99,Q8N3U4,Q8WVM7,P02545,Q9BTC0,Q14683 8
Signaling by insulin receptor 0.4466503395602457 0.9483289867825794 0.3429619985959087 1.0 0.7023742093337724 16 Q9Y487 1
Signaling by notch1 0.489757555458453 0.947207227633361 0.3435331931349767 1.0 0.7023868151820889 11 P78536,Q13573 2
Killing mechanisms 0.592419664927211 0.945921466219917 0.344188643756083 1.0 0.7023868151820889 2 P63000 1
Regulation of beta cell development 0.6078783569745554 0.9361975153760898 0.3491715022209578 1.0 0.70850675159907 5 P31751,Q13573 2
Hedgehog off state 0.3475421259129688 0.935088042005999 0.3497429286127476 1.0 0.70850675159907 54 P28070,P28074,P20618,P49721,P28072,Q9Y366,Q99436,P60900 8
Degradation of beta catenin by the destruction complex 0.3480233375728669 0.934752326154662 0.3499159535782057 1.0 0.70850675159907 52 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Signaling by fgfr1 in disease 0.4806398970331463 0.927274832896192 0.3537838577563805 1.0 0.7128635304296219 12 P11274,Q9UBW7 2
Potential therapeutics for sars 0.3675299678105562 0.925646605285352 0.354629664794774 1.0 0.7128635304296219 41 O75116,Q99720,P49354 3
Smooth muscle contraction 0.4733825394127425 0.9188457774078048 0.3581762445578857 1.0 0.7168612621904277 13 P67936,P09493 2
Signaling by pdgfr in disease 0.6031428884814354 0.9171497211607692 0.3590641894432067 1.0 0.7169142779184623 5 P42224,Q6UN15,P40763 3
Nonhomologous end joining nhej 0.4413934754994149 0.9168094410202368 0.3592425045220955 1.0 0.7169142779184623 16 P12956 1
Nef and signal transduction 0.5850041197473151 0.9137713128997303 0.3608370232039166 1.0 0.7169142779184623 2 P63000 1
Degradation of the extracellular matrix 0.4868691888367816 0.9080952387213512 0.363827905811648 1.0 0.7169142779184623 10 P78536,P07942,Q92542,O15484 4
Metabolism of lipids 0.3256381979942419 0.9052629804734942 0.365326083424738 1.0 0.7169142779184623 208 Q9HCL2,O43772,Q71SY5,Q8NCC3,Q96G23,Q8N8N7,P06280,P16278,Q15392,P35790,Q9Y6K0,P10619,Q16850,Q8N2A8,P07602,Q8IV08,P50897,P23786,Q9UMR5,Q9BWD1,O15254,Q9H4L5,Q15165,Q9NPH0,O43681 25
Cell cell junction organization 0.5031240049247572 0.9004623262530352 0.3678742654891227 1.0 0.7199095001030192 9 P35222,Q8N3R9,P35221,Q9BY67 4
Ion channel transport 0.3908095587369786 0.895683260787061 0.3704219530533663 1.0 0.7211037425403297 30 Q9Y487,Q93050,P16615,Q13555 4
Vitamin b5 pantothenate metabolism 0.5975480161877234 0.8947113313975757 0.3709414197476224 1.0 0.7211037425403297 5 Q9NVE7 1
Rhod gtpase cycle 0.3858405998611602 0.8875368962091347 0.3747899108569816 1.0 0.7263809964202024 31 P20700,P12814,Q8TAA9,Q9UEY8,O15173,P50402,Q8NHP6,Q07960,Q9Y2U8,Q14739,P42166,P49257,Q9BX68,Q02952,Q9Y6M7 15
Regulation of mecp2 expression and activity 0.4822790261801587 0.8850832912555512 0.3761117104751155 1.0 0.7271791186469797 10 Q13555,Q14739 2
O linked glycosylation 0.5334949945173424 0.884856728353719 0.3762339087960598 1.0 0.7271791186469797 7 Q8NAT1,Q10472,O43505 3
Downregulation of erbb2 signaling 0.5153224528766659 0.8769124706241818 0.380534182139439 1.0 0.7325043788921449 8 Q96RT1,P31751,Q16543,P31749 4
Cellular response to hypoxia 0.3583123972943056 0.876885630620516 0.380548761780731 1.0 0.7325043788921449 43 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Fatty acyl coa biosynthesis 0.4330402127738565 0.8668867132920101 0.3860040841841017 1.0 0.7373603888792019 16 P50897 1
Transcriptional regulation of white adipocyte differentiation 0.4632799938728178 0.8644468652146658 0.3873424574076389 1.0 0.7376584195218688 13 P11802,Q9NVC6,Q9NPJ6,Q71SY5,Q9BZK7,Q9Y2W1 6
Apc c mediated degradation of cell cycle proteins 0.3382757924732812 0.8626822083834199 0.3883122170799846 1.0 0.7383696543396738 59 P28070,P28074,P20618,P49721,Q12834,P28072,Q99436,P60900 8
Rnd2 gtpase cycle 0.4067691622153528 0.8492051751525951 0.3957671340954463 1.0 0.7471627262989831 19 Q86UP2,Q96RU3,Q07960,Q07065 4
Resolution of sister chromatid cohesion 0.3258992467794483 0.8381607748655181 0.4019404137151343 1.0 0.7518583951874754 72 Q8NBT2,P06493,Q96EE3,Q6P1K2,Q8N3U4,Q8WVM7,Q12834,P50748,Q9Y6D9,Q9NTI5,O60566,Q9H3R5,P57740,Q9NXR1,Q8NFH4,Q13362,P55735,Q96EA4,Q29RF7,P49792,Q9UQE7,Q15691,Q96IY1,Q2NKX8,Q9BS16,Q14738 26
G alpha 12 13 signalling events 0.489890351173375 0.8374441469600443 0.4023429595254482 1.0 0.7518583951874754 9 O75116,Q92888,Q13464 3
Gap junction degradation 0.5513910622114284 0.8270925374030876 0.4081846136593967 1.0 0.7557478123528032 6 Q00610,Q96CW1 2
Hdms demethylate histones 0.5039200844112183 0.8252118688131606 0.4092513162676188 1.0 0.7557478123528032 8 Q8NB78 1
Signaling by nuclear receptors 0.3294375974307611 0.8135265575793494 0.4159162261119173 1.0 0.76152681223333 65 Q8NB78,Q9HCL2,O94788,Q8WVM7,P11177,P31751,Q9UBI6 7
Transcriptional regulation by mecp2 0.4333291842156635 0.8069725900761175 0.4196822751016857 1.0 0.7649836036458929 15 Q13555,Q9HCE1,Q9NWH9,Q14739 4
Carnitine metabolism 0.5455688671610739 0.8031618404180144 0.4218811982321124 1.0 0.7675788448972239 6 O43772 1
Transcriptional regulation by runx2 0.3345120289794788 0.8015223047208181 0.4228293367201523 1.0 0.7675788448972239 52 O00231,P28070,P28074,P20618,P49721,P28072,Q99436,P60900 8
Intra golgi traffic 0.3976084885281818 0.798478483069554 0.4245928747603167 1.0 0.7689606176571803 21 Q9Y2V7,O00461,Q96JB2,O60476,O43752,Q8TBA6 6
Signaling by hedgehog 0.328874690303414 0.7835740360207363 0.4332900956745003 1.0 0.7788792035712603 62 P28070,P28074,P20618,P49721,P28072,Q9Y366,Q99436,P60900,P78536 9
Inactivation of cdc42 and rac1 0.6171294649722465 0.7816542871834326 0.4344177734908305 1.0 0.7788792035712603 3 O94813 1
Intracellular signaling by second messengers 0.3235976343823825 0.7815282357379332 0.4344918765131373 1.0 0.7788792035712603 95 P84095,P20618,P14373,P28072,Q9UL46,P60900,O00231,P28070,P28074,O43865,P49721,Q13362,Q16576,Q13330,O75530,P31749,Q13555,Q9NWH9,Q93009,P31751,Q99436 21
Dscam interactions 0.6148351648351661 0.7731435673157813 0.4394374196100037 1.0 0.7833229727421473 3 P63000,Q16539 2
Mapk family signaling cascades 0.3231719179184109 0.7719868696645132 0.4401222043140687 1.0 0.7833229727421473 91 O00231,P49354,Q13555,P28074,P28070,Q9NWH9,P20618,Q9Y4G8,Q14168,P07196,P28072,Q99436,P60900,Q13813,P49721 15
Separation of sister chromatids 0.3133675109532995 0.763225303504504 0.4453290407207644 1.0 0.7838254628917545 118 Q8NBT2,Q96EE3,P20618,Q16763,Q8WVM7,Q12834,P28072,Q9UL46,Q9Y6D9,P60900,O00231,O60566,Q9H3R5,P28070,P28074,Q9NXR1,P49721,Q13362,P55735,Q9UJX3,Q96EA4,Q29RF7,P49792,Q9UQE7,Q2NKX8,Q99436,Q9BS16 27
Amyloid fiber formation 0.5053630589755571 0.762778346862159 0.4455955967184495 1.0 0.7838254628917545 7 P05067 1
Dna damage recognition in gg ner 0.3925987127375761 0.7576467691900277 0.4486624736813254 1.0 0.7854081215815911 19 Q9H9Q2,Q9UNS2,P61201,Q9BT78,Q9H981 5
Rnd1 gtpase cycle 0.4229941123671071 0.7482333479989411 0.4543194195062008 1.0 0.7898014593518617 15 Q9BXS4,O75976 2
Cholesterol biosynthesis 0.3892493966411445 0.7436021677651644 0.457117191393535 1.0 0.7898014593518617 21 Q16850,Q15392 2
Non integrin membrane ecm interactions 0.4853630564642358 0.7420950489698773 0.4580297493541954 1.0 0.7898014593518617 8 P07942,P12814 2
Regulation of hmox1 expression and activity 0.3281963515495325 0.7393889253287433 0.4596708651668679 1.0 0.7898014593518617 50 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Plasma lipoprotein assembly remodeling and clearance 0.3888951724275025 0.7370351717914218 0.4611009608192704 1.0 0.7898014593518617 20 Q8WTV0,O15118,P61916 3
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.6046703296703311 0.7356869070020817 0.4619212595059272 1.0 0.7898014593518617 3 P42224,P40763 2
Signaling by kit in disease 0.6046703296703311 0.7356869070020817 0.4619212595059272 1.0 0.7898014593518617 3 P42224,P40763 2
Interleukin 2 family signaling 0.6046703296703311 0.7356869070020817 0.4619212595059272 1.0 0.7898014593518617 3 P42224,P40763 2
Signalling to ras 0.6046703296703309 0.7356869070020803 0.4619212595059281 1.0 0.7898014593518617 3 P11233,Q16539 2
Parasite infection 0.3861448024009777 0.7349581916609935 0.4623649566352708 1.0 0.7898014593518617 23 P35579,Q96JJ3,Q96F07,Q9UQB8,Q14185 5
Eph ephrin signaling 0.375362254006979 0.7322601597252306 0.4640097913314052 1.0 0.7898014593518617 28 P35579,P35580,Q7Z406,Q13464,O75116,Q92542 6
Switching of origins to a post replicative state 0.3241331664078855 0.727780852781915 0.4667477472350276 1.0 0.7898014593518617 61 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Signaling by alk in cancer 0.3516534486581194 0.7237644510005472 0.4692103572783019 1.0 0.7898654640443578 35 P35579,P26038,Q9P2E9,P12270,Q8IWJ2,Q14203,P49792,P06753,Q9HC35,O00291,P67936,P33176 12
Tcr signaling 0.3264810583605956 0.7227405293258942 0.4698393104828424 1.0 0.7899495812813853 51 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Beta catenin independent wnt signaling 0.3252435093559921 0.7207852327760332 0.4710416624517644 1.0 0.7901163123744476 57 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Defective intrinsic pathway for apoptosis 0.4174187491034355 0.7167875337224592 0.4735052049453436 1.0 0.7933042018644343 15 Q08379,P20700,P05067,P02545 4
Constitutive signaling by overexpressed erbb2 0.5786010113092636 0.7126316094526576 0.4760737465289195 1.0 0.7947724038616677 4 Q96RT1 1
Pre notch expression and processing 0.438514518443593 0.7082955952820112 0.4787617118643181 1.0 0.796434167875251 12 P15291,Q13573 2
Formation of atp by chemiosmotic coupling 0.442505696674358 0.7072172651362827 0.4794314709024636 1.0 0.796434167875251 11 P00846,O75964 2
Clathrin mediated endocytosis 0.3184648325899777 0.7043971676124444 0.4811854693958497 1.0 0.796434167875251 66 P11717,Q14108,P20645,Q9NZM3,P02786,Q9H9Q2,Q9UNS2,Q96RU3,Q9Y5X1,O43493,P61201,O14976,Q9BT78,O00291 14
Mismatch repair 0.4376761767308507 0.7040209390893959 0.4814197337466055 1.0 0.796434167875251 12 Q9UQ84 1
Costimulation by the cd28 family 0.414524597698347 0.7005400098276932 0.4835901278085863 1.0 0.796434167875251 15 P31751,P31749,Q13362 3
Diseases of dna repair 0.431100449981964 0.6938335291653693 0.4877866129775181 1.0 0.8003228192618786 13 Q9UQ84 1
Pten regulation 0.3116400918842991 0.6814903692648943 0.4955612586035665 1.0 0.8099662408503155 71 O00231,P28070,P28074,Q16576,P20618,P14373,Q93009,P49721,Q13330,P31751,O75530,P28072,Q99436,Q9UL46,P60900,P31749 16
Wax and plasmalogen biosynthesis 0.5425124404783761 0.6793092612505275 0.4969419295826753 1.0 0.8099662408503155 5 O00116 1
Sensing of dna double strand breaks 0.5659310363261801 0.6661019090999706 0.5053459643652851 1.0 0.815729661942294 4 Q92878,P52292 2
Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.5827060693286021 0.65632326232386 0.5116161531995558 1.0 0.8229077167330754 3 Q96T60 1
Rhoq gtpase cycle 0.3671063959518231 0.6545080827970483 0.5127845214209821 1.0 0.8238465116102209 27 P27105,P02786,Q86VI3,Q07960,Q96RU3,Q15758,Q9Y5S2,Q9Y6M7 8
Interconversion of nucleotide di and triphosphates 0.3748593957038478 0.6448771620941212 0.5190067926601649 1.0 0.825631587014969 19 P00390 1
Interleukin 27 signaling 0.5772000977254611 0.6368103227952654 0.5242484012986761 1.0 0.8280910882281999 3 P42224 1
Interleukin 35 signalling 0.5772000977254611 0.6368103227952654 0.5242484012986761 1.0 0.8280910882281999 3 P42224 1
Regulation of mrna stability by proteins that bind au rich elements 0.312017026246561 0.6354703261702075 0.5251217140327993 1.0 0.8280910882281999 66 P28070,P28074,P20618,Q13868,P49721,P28072,Q99436,P60900 8
Signaling by scf kit 0.5308415303360118 0.6353133874051619 0.5252240440382758 1.0 0.8280910882281999 5 P42224,P63000,P40763 3
Disinhibition of snare formation 0.517989563306775 0.6343122782257967 0.5258770451290851 1.0 0.8280910882281999 2 O00186 1
Activation of gene expression by srebf srebp 0.3709280063606646 0.6292151010475432 0.5292082438289296 1.0 0.8294069125029739 22 Q9HCL2 1
Cargo recognition for clathrin mediated endocytosis 0.3309375105514359 0.6224423636000329 0.533651031523104 1.0 0.8299274872141872 42 P11717,Q14108,P20645,Q9NZM3,P02786,Q9H9Q2,Q9UNS2,O43493,P61201,Q9BT78 10
Pi 3k cascade fgfr3 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1
Frs mediated fgfr3 signaling 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1
Frs mediated fgfr2 signaling 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1
Tie2 signaling 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1
Activated ntrk2 signals through frs2 and frs3 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1
Frs mediated fgfr1 signaling 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1
Pi 3k cascade fgfr1 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1
Signaling by flt3 itd and tkd mutants 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1
Stat5 activation downstream of flt3 itd mutants 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1
Pi 3k cascade fgfr4 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1
Stat5 activation 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1
Frs mediated fgfr4 signaling 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1
Pi 3k cascade fgfr2 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1
Pd 1 signaling 0.5097500686624465 0.6018619839548237 0.5472660114013197 1.0 0.8344975424212672 2 P41240 1
Signaling by leptin 0.5097500686624461 0.6018619839548227 0.5472660114013204 1.0 0.8344975424212672 2 P40763 1
Post translational modification synthesis of gpi anchored proteins 0.4386762990311638 0.6008058149982239 0.5479693305969509 1.0 0.8344975424212672 9 Q969N2 1
Signaling by interleukins 0.3045998168741096 0.5927633424022101 0.5533395435735982 1.0 0.8374386862461867 110 P08670,P28074,P20618,P14174,P05067,Q13126,P28072,Q99436,P49721 9
Apc c cdc20 mediated degradation of cyclin b 0.4181505095410202 0.5880442802905045 0.5565025715443119 1.0 0.8403703735528966 11 Q9UJX3,Q12834,P06493,Q16763 4
Cd28 dependent vav1 pathway 0.5175920835623862 0.5863171858389425 0.5576623841532706 1.0 0.8403703735528966 5 Q13177,P62993,P63000,Q16512 4
Piwi interacting rna pirna biogenesis 0.4182398798405971 0.573745159107034 0.5661402643526967 1.0 0.8485097063520015 10 Q8N2A8 1
P75ntr negatively regulates cell cycle via sc1 0.5020598736610726 0.5720723475786397 0.5672729620269941 1.0 0.8485097063520015 2 Q92769 1
Death receptor signalling 0.3597785250709099 0.5676507979784131 0.5702721069253847 1.0 0.8511794477307913 24 Q8TCT8,Q92542,P78536 3
Diseases of metabolism 0.3096032783439201 0.5631514080228013 0.5733317880167323 1.0 0.853937092299763 50 P16278,Q8NCH0,Q96L58,P15586,O43505,O14678,P15291,P08236,P10253,P54802,Q9NUN5,P10619 12
O linked glycosylation of mucins 0.5098109287411687 0.5580676457810289 0.5767981928104919 1.0 0.8554827933368243 5 Q10472,O43505 2
G2 m checkpoints 0.3047055517659821 0.5563497090298103 0.5779718114323367 1.0 0.8563220634155231 86 Q9UQ84,P28070,P28074,P20618,P40938,P28072,O96028,Q99436,P60900,P49721 10
P75 ntr receptor mediated signalling 0.3784642435281019 0.5500251210710894 0.5823021434618023 1.0 0.8584816253730735 16 P78536,Q92542 2
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.4125060021529267 0.5471984040556763 0.5842424325075894 1.0 0.8584816253730735 10 Q16763,Q12834 2
Pre notch processing in golgi 0.5058484383324006 0.5438433490644985 0.5865492756056521 1.0 0.8584816253730735 5 P15291 1
Slc transporter disorders 0.3289154967833096 0.5437874864205832 0.5865877209241699 1.0 0.8584816253730735 35 P11166,O00400,Q9BTX1,Q96EE3,P55735,P12270,P57740,P53985,Q8N1F7,Q7Z3B4,P08195,P49792 12
Regulation of cholesterol biosynthesis by srebp srebf 0.3440568735542521 0.5311745890229412 0.5952978002143423 1.0 0.863825541196713 29 Q9HCL2 1
Diseases associated with glycosylation precursor biosynthesis 0.4480350719287994 0.5261224901969421 0.5988031033659007 1.0 0.8662357008650452 7 P10619 1
Vitamin c ascorbate metabolism 0.5420534162258892 0.5166244383641295 0.6054183525934371 1.0 0.8708236952215923 3 P11166 1
Alk mutants bind tkis 0.4434803762611705 0.508323177439658 0.6112267183498874 1.0 0.8755028790198734 7 Q9HC35,O00291 2
Diseases associated with glycosaminoglycan metabolism 0.4425358529271619 0.5046550521906275 0.6138011359119777 1.0 0.8771255583164064 7 Q96L58,P15291 2
Nephrin family interactions 0.4281115341166191 0.498167638438505 0.6183658898920914 1.0 0.879190251118019 8 Q01082,P12814,Q13813,O43707 4
Deposition of new cenpa containing nucleosomes at the centromere 0.3951060457550945 0.4939298659202039 0.6213557113802801 1.0 0.8798896455626278 12 Q9BS16 1
Interferon signaling 0.2972885104297937 0.4881113469463375 0.6254709742641129 1.0 0.8831504528747453 67 O15344,Q96EE3,P30511,P42224,Q9Y4X5,P19474,P10321,P12270,P57740,P55265,Q7Z3B4,P29372,Q8NFH4,Q9BTX1,P55735,P04439,Q8N1F7,P49792,Q13325,Q13555 20
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.5327439982021527 0.4862465473655187 0.626792372515788 1.0 0.8831504528747453 3 P11802 1
Interleukin 20 family signaling 0.5269066376839309 0.4675520146614727 0.6401049870585744 1.0 0.8906154404916529 3 P42224 1
Interleukin 6 signaling 0.5269066376839309 0.4675520146614727 0.6401049870585744 1.0 0.8906154404916529 3 P42224 1
Interleukin 6 family signaling 0.5269066376839309 0.4675520146614727 0.6401049870585744 1.0 0.8906154404916529 3 P42224 1
Apc cdc20 mediated degradation of nek2a 0.3851424281014114 0.4626518484846421 0.6436139378679973 1.0 0.8920897151714327 13 O60566,Q16763,Q12834 3
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3851424281014114 0.4626518484846421 0.6436139378679973 1.0 0.8920897151714327 13 O60566,Q16763,Q12834 3
Met promotes cell motility 0.392975455681698 0.4592099831807193 0.6460833822233272 1.0 0.8942352510340551 10 P07942,Q9NWH9 2
Mitotic metaphase and anaphase 0.2745116726514146 0.4579106110388231 0.6470166631703851 1.0 0.8946481633042911 153 Q86XL3,Q8NBT2,Q96EE3,P20618,Q16763,Q8WVM7,P02545,Q12834,P28072,Q9UL46,Q9Y6D9,P60900,O00231,O60566,Q9H3R5,P28070,P28074,Q14739,Q9NXR1,P49721,P20700,Q13362,Q9BTX1,P55735,Q9UJX3,Q96EA4,Q8N1F7,Q29RF7,P49792,Q9UQE7,Q2NKX8,Q99436,Q9BS16 33
Small interfering rna sirna biogenesis 0.5035807128189961 0.4512066000849135 0.6518406532154877 1.0 0.8985019724445508 4 O75569 1
Pyruvate metabolism and citric acid tca cycle 0.3152504405670104 0.4499306141522501 0.652760472294736 1.0 0.8985019724445508 37 O95563,P21796,P53985,P48735 4
Stat3 nuclear events downstream of alk signaling 0.5023358065402752 0.4472124559834572 0.6547216686993402 1.0 0.899125566469172 4 Q96ST3,Q92769,P40763 3
Regulation of insulin secretion 0.3806560031868828 0.4412644506796819 0.6590215588788855 1.0 0.899803920708942 13 P46940,P11166,Q9UBI6,O43865 4
Pre notch processing in the endoplasmic reticulum 0.4663553968689855 0.4411266967927643 0.6591212773118722 1.0 0.899803920708942 2 Q9H488 1
Opioid signalling 0.341256955734167 0.440346852025481 0.6596859120598559 1.0 0.899803920708942 19 O43865 1
Neddylation 0.2932037033959241 0.4382020209789456 0.6612398436986138 1.0 0.9010511990051708 81 O00231,P60900,O60826,Q16576,P28074,Q9UNS2,P28070,P20618,Q9H9Q2,Q9UBW8,Q7Z4G1,P61201,Q92564,Q9BT78,P28072,Q99436,Q9UL46,P49721 18
Interleukin 4 and interleukin 13 signaling 0.3791906079242515 0.4343353024513988 0.6640449717582761 1.0 0.903126800393254 13 P08670,P09601,Q07820,P31749 4
Met activates ptk2 signaling 0.4726407822311689 0.4295396974142842 0.6675305109398249 1.0 0.9052458998211868 5 P07942 1
Sensory processing of sound 0.338074633914437 0.4218250501645936 0.6731527198844374 1.0 0.91024201757886 19 P35579,Q01082,Q13813,O14936 4
Syndecan interactions 0.4451661652226334 0.4192605323147208 0.6750257374287023 1.0 0.9118995820105864 6 P17301,P12814,O14936 3
Gab1 signalosome 0.5098901098901115 0.4147338279729401 0.6783367656242727 1.0 0.9128715403673356 3 P62993,P41240 2
Signal regulatory protein family interactions 0.5098901098901114 0.4147338279729401 0.6783367656242727 1.0 0.9128715403673356 3 P62993,Q08722 2
Deactivation of the beta catenin transactivating complex 0.3813027623845995 0.408704066553077 0.6827568491268452 1.0 0.9170680652237606 10 P31751,P31749 2
Listeria monocytogenes entry into host cells 0.4026300560270959 0.3987521878581186 0.6900758098478708 1.0 0.9198834589173605 8 P42566,Q9NWH9 2
Negative regulation of the pi3k akt network 0.3492492635705874 0.3925557626868922 0.6946476180950965 1.0 0.9215547517862458 16 Q13362,P84095,Q9NWH9,P31751,P31749 5
Mecp2 regulates transcription of neuronal ligands 0.5021978021978037 0.3917352133537207 0.6952538688067986 1.0 0.9215547517862458 3 P51608,Q96ST3 2
Adherens junctions interactions 0.4115594131781473 0.3892816864050446 0.6970677821334641 1.0 0.9222296333295056 7 P35222,P35221,Q9BY67 3
Rho gtpases activate iqgaps 0.3712779299995678 0.3845634386649921 0.7005608863915573 1.0 0.92310583730407 12 Q86VI3,P35222,P35221 3
Activated notch1 transmits signal to the nucleus 0.4820730995965838 0.3842103170304916 0.7008225721996104 1.0 0.92310583730407 4 P78536 1
Mitotic spindle checkpoint 0.2869405704430443 0.3821886966672906 0.7023214053728648 1.0 0.92310583730407 67 Q8NBT2,Q96EE3,Q6P1K2,Q16763,Q12834,Q9Y6D9,O60566,Q9H3R5,P57740,Q9NXR1,Q8NFH4,Q13362,P55735,Q9UJX3,Q96EA4,P49792,Q15691,Q96IY1,Q2NKX8,Q9BS16,Q14738 21
Reproduction 0.3255317726194815 0.3784086872027071 0.7051270157092906 1.0 0.92310583730407 27 P20700,Q9UQE7,P11802,Q9UH99,Q92878,Q8N3U4,Q8WVM7,P02545,P15291,Q9BTC0,Q14683 11
Pkmts methylate histone lysines 0.3534469925487228 0.3762807350245141 0.7067081999229474 1.0 0.92310583730407 15 O75530 1
Polymerase switching 0.3596743602506363 0.3733180827108707 0.7089117196405985 1.0 0.924867234234818 14 P41440 1
Programmed cell death 0.2877068461951152 0.3669192577801668 0.7136792461976924 1.0 0.9270231033240206 106 P20700,O00231,P60900,P49354,P08670,P28070,P28074,Q13464,P20618,P02545,O75955,P28072,Q99436,P41440,Q13813,P49721 16
Met activates rap1 and rac1 0.4278767477718062 0.361534351242581 0.717700030450036 1.0 0.928735611632204 6 Q9NWH9 1
Cohesin loading onto chromatin 0.3697631021498927 0.3605604122886637 0.7184280876620739 1.0 0.928735611632204 10 Q9UQE7,Q8WVM7,Q8N3U4,Q29RF7,Q9NTI5 5
Apoptotic execution phase 0.3152048365635996 0.3537954869470252 0.7234921559287042 1.0 0.9326628066821082 30 P20700,P49354,P08670,P02545,Q13813 5
Phenylalanine metabolism 0.4383411150782698 0.3486446653965739 0.7273560910807881 1.0 0.9359312624044114 2 P09417 1
Metabolism of water soluble vitamins and cofactors 0.2932292822036218 0.3442706635300925 0.7306427444636827 1.0 0.936738514057624 45 P11166,Q9NVS9,Q9NPF0,Q9H2D1,Q96EN8,P43490,Q9NUN5,O14678,Q8NFF5,Q9NRN7,P78417,O00764,Q9HC21,P41440,Q99707,Q9NVE7 16
Tcf dependent signaling in response to wnt 0.282015069174541 0.3389731059742884 0.7346299903329179 1.0 0.9390658827208512 68 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Polymerase switching on the c strand of the telomere 0.3372231831126751 0.3316555337043869 0.7401493808266801 1.0 0.9412188425855528 16 P41440 1
Neuronal system 0.2843939681168571 0.3282750090476694 0.7427037380198636 1.0 0.9427653755585476 58 Q14012,P54619,Q13555,P80404,Q13136,Q14168,Q9UBI6,O75955,P10586,P41440,P07196 11
Rnd3 gtpase cycle 0.3203479053490922 0.3241720031598482 0.7458078167964566 1.0 0.9439970311709984 18 Q86UP2,Q07065,O75976 3
Nuclear receptor transcription pathway 0.4295523207909837 0.3218150182862841 0.7475928361229027 1.0 0.9439970311709984 2 Q15648 1
Dna replication pre initiation 0.2791156337255669 0.3102212752769938 0.7563926927445142 1.0 0.949872820032995 68 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7
Vegfr2 mediated vascular permeability 0.353931840153442 0.3028390873650514 0.7620124938550514 1.0 0.9514108698395848 11 P31749,P31751,P35221 3
Signaling by wnt in cancer 0.355206252760706 0.3026968836641108 0.762120872922257 1.0 0.9514108698395848 10 P48729,P35222,Q13362 3
Ikba variant leads to eda id 0.4218621257896104 0.2992683328564875 0.7647353146950711 1.0 0.9518657759764622 2 O15111 1
Signaling by rho gtpases miro gtpases and rhobtb3 0.3099201057668907 0.2924709275157063 0.7699265850838894 1.0 0.9532746558727594 282 P78371,Q8NBT2,P84095,Q86VI3,P30519,Q96N67,P06753,Q13505,Q12834,Q9Y5S2,Q9UQB8,Q92888,P35579,Q9H3R5,Q96JJ3,Q86UP2,Q7Z406,Q07960,Q07065,P02786,O75116,Q9BXS4,P67936,Q13813,P33176,P20700,P12814,Q9NZM3,O15173,P55735,Q96RU3,Q13464,O75976,Q96F07,Q96EA4,Q7L576,P41440,P11274,Q14185,Q8NBN3,Q9Y6M7,P35580,P08670,Q01082,O43663,Q9BT78,O75955,Q96HY6,Q9BS16 49
Keratan sulfate degradation 0.4268516516183419 0.2897977017859582 0.7719710061699891 1.0 0.9536687208582376 5 P16278,P15586 2
Translesion synthesis by polk 0.3509106113295766 0.2862909664003602 0.774655276473877 1.0 0.9540990249577732 10 P41440 1
Esr mediated signaling 0.2811694204792111 0.270386611930112 0.7868628387866026 1.0 0.9607363430245434 47 Q9UQE7,Q9HCL2,Q9HCE1,Q8WVM7,P31751,Q9UBI6,P31749 7
Platelet homeostasis 0.3435795331076976 0.2681263418047017 0.7886020701238385 1.0 0.9618105391624924 12 Q9UBI6,P16615,Q13362 3
Regulation of tp53 expression and degradation 0.3403439201006695 0.2627292063320163 0.7927593039702285 1.0 0.9618105391624924 13 Q93009,P31751,P31749,Q13362 4
Grb2 sos provides linkage to mapk signaling for integrins 0.4081296347157281 0.2612675346474137 0.7938862008843 1.0 0.9618105391624924 2 P62993 1
Apoptosis 0.2788557949159255 0.2581729558102715 0.7962734287186044 1.0 0.9638510676348392 92 P20700,O00231,P49354,P08670,P28070,P28074,Q13464,P20618,P02545,P28072,Q99436,P60900,Q13813,P49721 14
Dna double strand break repair 0.2762133587517754 0.2560324576059755 0.7979257748501101 1.0 0.96421733856244 56 O96028,Q9UQ84,P12956 3
Diseases of programmed cell death 0.3007966063757459 0.2506238615090529 0.8021049315769013 1.0 0.9676077470820668 29 P20700,Q08379,P02545,O75530,P05067 5
Neurotransmitter release cycle 0.3581140970496762 0.2453106188184973 0.806215930279679 1.0 0.9690232433745896 8 P80404,Q13136 2
Linoleic acid la metabolism 0.4015380390002708 0.2440962186134425 0.8071563010965563 1.0 0.9690232433745896 2 P33121 1
Eph ephrin mediated repulsion of cells 0.3385697801678712 0.2437754350812522 0.8074047464313472 1.0 0.9690232433745896 11 Q92542 1
Bbsome mediated cargo targeting to cilium 0.3468234453564495 0.2371655510169016 0.8125283602675131 1.0 0.9711407665569102 9 P78371 1
Diseases of immune system 0.4390450754412024 0.2273002879332384 0.8201902492283719 1.0 0.9711407665569102 3 O15111 1
Cytokine signaling in immune system 0.2714628985987332 0.2231021151311809 0.8234560322053235 1.0 0.9725106791489349 181 O15344,P30511,P20618,P14174,Q13126,P28072,P60900,P05067,O00231,P19474,P28070,P28074,P49721,P20700,P55735,P78536,P08670,Q13555,Q99436 19
Inlb mediated entry of listeria monocytogenes into host cell 0.3752892981578248 0.2092102425961602 0.8342841169121398 1.0 0.9761511443523126 6 Q9NWH9 1
Synthesis of substrates in n glycan biosythesis 0.3102117493699463 0.2058386398492171 0.8369169572007933 1.0 0.9761511443523126 16 P10619 1
S phase 0.2742324948059929 0.2042730869185779 0.8381401000692013 1.0 0.9761511443523126 101 Q9UQE7,O00231,P60900,Q29RF7,P28070,P28074,P20618,Q16763,O75419,Q8WVM7,P31751,P40938,Q14566,Q9BRT9,P28072,Q99436,P41440,P49721 18
Energy dependent regulation of mtor by lkb1 ampk 0.3517752960088014 0.2014727804657463 0.8403289110802903 1.0 0.9761511443523126 7 Q15382,P54619 2
Mitotic telophase cytokinesis 0.3245177534734972 0.2008564813309674 0.8408107970370771 1.0 0.9761511443523126 13 Q9UQE7,Q02241,Q8WVM7,Q8N3U4,Q29RF7,Q14683,Q9NTI5 7
Signaling by braf and raf1 fusions 0.2976000824736072 0.1999649375592678 0.8415080030404987 1.0 0.9761511443523126 24 Q9NRY5,Q96PU8,Q13555,Q6WCQ1,P02545 5
Hdr through homologous recombination hrr 0.2955348228178907 0.195746711353542 0.8448084212171374 1.0 0.9761511443523126 26 Q9UQ84,P41440 2
Adenylate cyclase inhibitory pathway 0.4239010989011006 0.1951605695459501 0.8452672464235349 1.0 0.9761511443523126 3 P63096,P04899 2
Regulation of gene expression in beta cells 0.408655524971702 0.1942083240657538 0.8460127652989298 1.0 0.9761511443523126 4 P31751 1
Phosphorylation of emi1 0.4222296108088759 0.1918001580211615 0.8478987471791652 1.0 0.9761511443523126 3 Q12834 1
Cell cell communication 0.289710481383548 0.1870693876584185 0.8516062295438562 1.0 0.9779243499814942 29 P12814,P35221,Q9BY67,O43707,Q01082,Q8N3R9,Q13813,P35222,O14936 9
Cell cycle checkpoints 0.2565033882476371 0.181355890044553 0.8560882393495055 1.0 0.981471382622826 154 Q8NBT2,Q96EE3,Q92878,P20618,Q16763,O75419,P40938,Q12834,P28072,Q9UL46,Q9Y6D9,Q9Y619,P60900,Q9UQ84,O00231,O60566,Q9H3R5,P28070,P28074,Q9NXR1,P49721,Q13362,P55735,Q9UJX3,Q96EA4,O96028,P49792,Q2NKX8,Q99436,Q14566,Q9BS16 31
Ncam signaling for neurite out growth 0.3605584428137088 0.1738167749509753 0.8620094605682826 1.0 0.9841847260227016 6 Q13813 1
Tp53 regulates transcription of death receptors and ligands 0.3707772589947731 0.1735994149705959 0.8621802918254611 1.0 0.9841847260227016 2 P04637 1
Type i hemidesmosome assembly 0.3696786597088676 0.1713822620664341 0.863923201252135 1.0 0.9841847260227016 2 Q15149 1
Assembly of collagen fibrils and other multimeric structures 0.3696786597088676 0.1713822620664341 0.863923201252135 1.0 0.9841847260227016 2 Q15149 1
Condensation of prometaphase chromosomes 0.3244242808238441 0.16830107277467 0.8663464299493218 1.0 0.9848478520417562 9 P06493,O95347,Q9NTJ3,Q15021,Q15003,P67870 6
Ca2 pathway 0.3577013083994919 0.1673542469518957 0.8670913230360631 1.0 0.9848478520417562 6 Q9HCE1,Q9UBI6 2
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.40824175824176 0.1651588727011975 0.8688189354775748 1.0 0.9848478520417562 3 P63000,O14786 2
Homologous dna pairing and strand exchange 0.2985528292593037 0.157078667033664 0.8751828501000409 1.0 0.9877957181119394 16 Q9UQ84 1
Hdr through single strand annealing ssa 0.2985528292593037 0.157078667033664 0.8751828501000409 1.0 0.9877957181119394 16 Q9UQ84 1
Signaling by erbb2 in cancer 0.3713449565403116 0.1565165553531337 0.8756258707748845 1.0 0.9877957181119394 5 Q96RT1 1
Signaling by erbb2 ecd mutants 0.3713449565403116 0.1565165553531337 0.8756258707748845 1.0 0.9877957181119394 5 Q96RT1 1
Glucagon like peptide 1 glp1 regulates insulin secretion 0.3701071880895624 0.1540576100321204 0.8775643114791303 1.0 0.9883997720816105 5 P46940,Q9UBI6 2
Signaling by erbb2 0.3106619034908053 0.1490928692870219 0.8814803524886972 1.0 0.9906613141197892 12 Q96RT1,P31751,Q16543,P31749 4
Intraflagellar transport 0.3056996864341485 0.1477106267971159 0.8825711446688702 1.0 0.9908416769628876 14 Q9Y366,A0AVF1 2
Unwinding of dna 0.3094106356498832 0.1460734194144907 0.8838634295532231 1.0 0.9908416769628876 10 Q14566,Q9BRT9 2
Platelet sensitization by ldl 0.3278939409882084 0.1426037178561819 0.8866031610699394 1.0 0.991447503132972 7 Q14738,Q13362 2
E2f enabled inhibition of pre replication complex formation 0.3628637351292202 0.1401359049316304 0.8885526124503871 1.0 0.9920599930545916 5 Q9Y619 1
Tp53 regulates metabolic genes 0.269139125753199 0.1373941773762004 0.8907192331842564 1.0 0.9920599930545916 40 P20674,P54619,Q7LG56,P31751,P00390,P31749,P00403 7
Synthesis of dna 0.2659784528666107 0.1329076530802033 0.8942664143211674 1.0 0.9921428171484448 88 O00231,P60900,P28070,P28074,P20618,P40938,Q9BRT9,P28072,Q99436,P41440,P49721 11
Regulated necrosis 0.2816163466674679 0.1315120387504301 0.8953702637416256 1.0 0.9924183808938744 19 P41440 1
Processing of dna double strand break ends 0.2805484471413052 0.130812697708152 0.8959234779964573 1.0 0.9924183808938744 28 O96028,Q9UQ84 2
Integrin cell surface interactions 0.3211231797742668 0.1277917496213718 0.8983137793780409 1.0 0.9928424105727596 7 Q9BX67,P17301,P35613 3
Translesion synthesis by polh 0.3033681105859644 0.1270390935778116 0.8989094570019749 1.0 0.9928424105727596 13 P41440 1
Mitotic g1 phase and g1 s transition 0.2615422007862957 0.1125599809348174 0.9103794139364472 1.0 0.9995749705444285 81 O00231,P28070,P28074,P20618,O75419,P31350,P31751,Q14566,P28072,Q99436,P60900,P49721 12
Negative regulation of met activity 0.3076110447635577 0.1119108285445725 0.910894110604926 1.0 0.9995749705444285 8 Q9NWH9 1
Transcriptional activation of mitochondrial biogenesis 0.2982824346418836 0.1109318577570206 0.9116703826661344 1.0 0.9995749705444285 13 O00411,Q96RR1 2
Sars cov infections 0.2568191784457093 0.1071183381008263 0.914695099170704 1.0 0.9995749705444285 69 Q99720,P49354,Q13464,O75116,Q14457 5
Homology directed repair 0.2622467376295883 0.1052077170179513 0.9162109874138132 1.0 0.9995749705444285 43 O96028,Q9UQ84 2
Signaling by hippo 0.30770878584314 0.1009542108688868 0.9195868088325344 1.0 0.9995749705444285 7 Q13043,Q4VCS5 2
Signaling by receptor tyrosine kinases 0.2593482819881195 0.1009290467794472 0.919606784841406 1.0 0.9995749705444285 124 P07942,Q9Y487,Q96JJ3,Q13464,Q9NWH9,O75116,Q96F07,Q93050,P31751,Q8WX92,O43865,P78536,Q7L576,Q9UQB8,Q92542,Q14185 16
Rhof gtpase cycle 0.2780024432173055 0.0975064255796248 0.9223242316731556 1.0 0.9995749705444285 17 P20700,P12814,Q8TAA9,Q9UEY8,Q07960,P42166,Q02952,Q9Y6M7 8
Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.3362144257601666 0.0958158054360232 0.923666864193645 1.0 0.9995749705444285 5 P31751 1
Inositol phosphate metabolism 0.3178443772339894 0.0912672010678067 0.9272802789461084 1.0 1.0 6 Q96PE3,Q9NPH2,Q9BW91,P19174,Q01968 5
Adaptive immune system 0.2722811688349957 0.0897969721357841 0.9284485543567712 1.0 1.0 206 Q9Y496,P30511,P20618,Q16763,Q5KU26,Q12834,P28072,Q9UL46,P60900,P55786,O00231,P19474,P10321,Q9UIQ6,P28070,P28074,Q14203,O75935,O43865,P10619,P49721,O94874,Q13049,P33176,Q13362,P55735,Q9UJX3,P52732,P04439,O95239,P31749,P52888,Q9NZ08,P31751,Q99538,Q99436 36
Translocation of slc2a4 glut4 to the plasma membrane 0.2608013095693706 0.0865198007608968 0.931053216359647 1.0 1.0 40 P35579,Q9UIQ6,P54619,P31751 4
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.2904599380962877 0.0835544300076131 0.9334106997640574 1.0 1.0 9 Q93009,Q16763 2
Dap12 interactions 0.3262781748213254 0.08203614217945 0.9346179730009618 1.0 1.0 5 P62993,P01889,P10321,P63000 4
Akt phosphorylates targets in the cytosol 0.3059935382417012 0.07371471312729 0.9412373912589028 1.0 1.0 6 P31751 1
Cell junction organization 0.2669056744214946 0.0713863234358335 0.943090294156086 1.0 1.0 19 Q8N3R9,Q9BY67 2
Transcriptional regulation by e2f6 0.2829610529756042 0.0685757798341913 0.945327298363242 1.0 1.0 12 P31350,O75530 2
Constitutive signaling by egfrviii 0.3261885133278484 0.0670429580386523 0.9465475045404904 1.0 1.0 4 P62993,P07900,Q16543 3
Constitutive signaling by ligand responsive egfr cancer variants 0.3261885133278484 0.0670429580386523 0.9465475045404904 1.0 1.0 4 P62993,P07900,Q16543 3
Signaling by egfr in cancer 0.3261885133278484 0.0670429580386523 0.9465475045404904 1.0 1.0 4 P62993,P07900,Q16543 3
Meiosis 0.2686466778487039 0.0668290375378563 0.9467178064645988 1.0 1.0 26 P20700,Q9UQE7,P11802,Q9UH99,Q92878,Q8N3U4,Q8WVM7,P02545,Q9BTC0,Q14683 10
Signal amplification 0.2836313617606746 0.0660113543996318 0.9473687856694974 1.0 1.0 8 Q16539,Q14344,P08754,Q13685,P04899,Q9UBI6,P63096 7
Synthesis of pips at the early endosome membrane 0.3234349453993151 0.0643806643470927 0.9486671256982284 1.0 1.0 4 Q96PE3 1
Pecam1 interactions 0.326098901098903 0.0611831800045689 0.9512133250468822 1.0 1.0 3 Q06124,P06756 2
Constitutive signaling by akt1 e17k in cancer 0.2831489140842055 0.0604369487170864 0.9518076316073332 1.0 1.0 7 O15111,P31751,P31749 3
Pp2a mediated dephosphorylation of key metabolic factors 0.3233516483516502 0.059129294061128 0.9528491261681332 1.0 1.0 3 P30153,Q14738 2
G1 s specific transcription 0.2766838147121669 0.0571543789413046 0.9544222190484488 1.0 1.0 11 P31350,Q9Y619,O75419 3
Neurexins and neuroligins 0.2734213819597552 0.0553117757352158 0.9558900808491002 1.0 1.0 10 Q14168 1
Extra nuclear estrogen signaling 0.2774304120887577 0.0548396427955911 0.9562662175219244 1.0 1.0 12 P31751,Q9UBI6 2
Defects in vitamin and cofactor metabolism 0.2775603692615556 0.0523179098960324 0.9582753828260931 1.0 1.0 13 Q9NUN5 1
Response of eif2ak1 hri to heme deficiency 0.3042044517724773 0.0483005608907998 0.9614767075510012 1.0 1.0 4 P05198,P41091,P08243 3
Kinesins 0.2619438896753199 0.0460179450121506 0.963295947009254 1.0 1.0 21 Q9Y496,Q07866,O95235,Q02241,P52732,Q14807,O95239,P33176 8
M phase 0.2734802797700281 0.0437462827081837 0.9651066462412412 1.0 1.0 218 Q86XL3,Q01105,Q8NBT2,Q96EE3,Q8N3U4,Q16763,P20618,Q9H6D7,P02545,Q8WVM7,Q9NTJ3,P28072,Q12834,Q9UL46,Q9Y6D9,P60900,O00231,O60566,Q96CW5,Q9H3R5,Q08379,P28070,P28074,P12270,Q14203,Q14739,O75935,Q9NXR1,Q15021,O43805,P49721,P20700,O15078,Q13362,Q9BTX1,P55735,Q9UJX3,Q96EA4,Q8N1F7,Q29RF7,P49792,Q9UQE7,O94927,Q96CS2,O95684,Q9BSJ2,Q2NKX8,Q99436,Q9UPN4,Q9BS16 50
Nuclear envelope breakdown 0.2520319799121704 0.0386081904423536 0.9692027721343192 1.0 1.0 41 P20700,P06493,Q8NFH4,Q96EE3,Q9BTX1,P12270,P55735,P57740,Q9Y2U8,P02545,P42166,Q8N1F7,Q7Z3B4,P49792 14
Cdc6 association with the orc origin complex 0.2767243748282619 0.0321304390137074 0.9743680291137532 1.0 1.0 4 O43913,Q9Y619,Q9UBD5 3
Zbp1 dai mediated induction of type i ifns 0.271852666300172 0.0306242961265443 0.975569165727712 1.0 1.0 5 O15111,O14920,Q9NZI8,Q08211 4
Rip mediated nfkb activation via zbp1 0.2718526663001722 0.0306242961265443 0.975569165727712 1.0 1.0 5 O15111,O14920,Q9NZI8,Q08211 4
Rho gtpase effectors 0.250653715264051 0.027358154599011 0.9781740735375362 1.0 1.0 129 Q8NBT2,P84095,Q86VI3,Q12834,Q9UQB8,Q9Y6D9,P35579,O60566,P35221,Q9H3R5,Q86UP2,Q7Z406,O75116,Q9NXR1,Q9Y6W5,P33176,Q13362,P55735,Q13464,Q96F07,Q96EA4,Q7L576,P49792,P35580,O43663,Q2NKX8,Q9BS16 27
Platelet aggregation plug formation 0.2452570800110045 0.0165648657077538 0.9867837538142594 1.0 1.0 6 P62993,P31749,Q9Y490,P18031,P41240 5
Integrin signaling 0.2452570800110045 0.0165648657077538 0.9867837538142594 1.0 1.0 6 P62993,P31749,Q9Y490,P18031,P41240 5
Processing of intronless pre mrnas 0.2531782646540392 0.0059936373920085 0.9952177978942732 1.0 1.0 16 Q5KU26,Q92797 2
Metabolism of vitamins and cofactors 0.2437824577408127 0.005065355670708 0.995958448198281 1.0 1.0 57 Q96EN8,Q9Y5Z9,Q9HC21,Q99707,Q9NVE7,P11166,Q9NVS9,O14678,Q9NRN7,P78417,Q9H2D1,P43490,Q9BQG2,Q8N0U8,Q9NPF0,P41440,P31749,Q9NUN5,O00764,Q8NFF5 20
Mtor signalling 0.2508499987912997 3.137203293250283e-05 0.9999749687392864 1.0 1.0 16 P31751,P54619,P31749 3
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