diff --git a/interpro_active_site/advanced/idx2term.json b/interpro_active_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/basic/idx2term.json b/interpro_active_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_active_site/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_active_site/consensus.joblib b/interpro_active_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..aeee124cca0d249d80f92b7c28e2fcfd978b15bb --- /dev/null +++ b/interpro_active_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:910710eb4237e62ed70a5171238ed653b2a648dbf37f7a1e3aba26c4318559f1 +size 94905 diff --git a/interpro_active_site/df_merge.tsv b/interpro_active_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_active_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_active_site/metrics.json b/interpro_active_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..b8ffd6c67567e7578ca7cb0c67d4950d34f661b2 --- /dev/null +++ b/interpro_active_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 57, + "title": "Average number of proteins per term", + "value": 2.789473684210526 +} \ No newline at end of file diff --git a/interpro_active_site/paths.json b/interpro_active_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ab8e301117387edfe6452a4f44d76bc602041c33 --- /dev/null +++ b/interpro_active_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/interpro_active_site/result.tsv b/interpro_active_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..629176e27260d031cede1493daeb9a21fd09f3ef --- /dev/null +++ b/interpro_active_site/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Histidine acid phosphatase active site [IPR033379] 0.9335347432024158 2.4353292079727376 0.0148782464950083 0.5744752459520164 0.030287858936267 2 Q9NPH0 1 +Ribonucleotide reductase small subunit, acitve site [IPR030475] 0.8728371326558649 2.1801251703206916 0.0292481844650627 0.8158515563318138 0.049033721014958 2 Q7LG56 1 +Serine carboxypeptidase, serine active site [IPR018202] 0.903846153846154 1.894351738414526 0.0581783378279663 0.9671742632806172 0.0850298783639507 3 Q9HB40,P10619 2 +Cysteine peptidase, cysteine active site [IPR000169] 0.4846501045783905 0.4697924223264775 0.6385033288025301 1.0 0.6739757359582262 5 O15484 1 +Protein-tyrosine phosphatase, active site [IPR016130] 0.4008987735281891 0.3520844611082515 0.7247749214673289 1.0 0.7377173307792455 7 P10586 1 diff --git a/interpro_active_site/selections.json b/interpro_active_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..07c0302126045ce28e8ef1e31a38dba5372afbf5 --- /dev/null +++ b/interpro_active_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase, F0 complex, subunit A, active site [IPR023011]", "ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA/RNA non-specific endonuclease, active site [IPR018524]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycoside hydrolase, family 2, active site [IPR023232]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["AAK1", "ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT1", "AKT2", "AMPD2", "APEH", "ATP5A1", "ATP5B", "ATP6", "ATP6V1A", "ATP6V1B2", "AURKA", "AURKB", "BLMH", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPN5", "CDC42BPB", "CDC7", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK2", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EIF2AK2", "ENDOG", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GSK3A", "GSK3B", "GSR", "GUSB", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "LDHA", "LDHB", "LONP1", "LONP2", "MAP2K1", "MAP3K7", "MAPK1", "MAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "NCEH1", "NEK3", "NEK9", "NME1", "NME2", "OXCT1", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA2", "PRKACA", "PRKCD", "PRPF4B", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "RIPK1", "RNASET2", "RNGTT", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SUCLG1", "TALDO1", "TIGAR", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UMPS", "UNG", "VRK1", "VRK2", "WNK1"], "leading_proteins": ["ACP6", "CAPN5", "CTSA", "PTPRF", "RRM2B", "SCPEP1"]} \ No newline at end of file diff --git a/interpro_binding_site/advanced/idx2term.json b/interpro_binding_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_binding_site/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_binding_site/basic/idx2term.json b/interpro_binding_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..1f2df466d020a9613ebb803cec2bf89e8e4d80ca --- /dev/null +++ b/interpro_binding_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "EF-Hand 1, calcium-binding site [IPR018247]"} \ No newline at end of file diff --git a/interpro_binding_site/basic/plot_0.png b/interpro_binding_site/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..441880da0a57cdc65756a72bd7f040b4162b271a --- /dev/null +++ b/interpro_binding_site/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:a9ab77e85a29a7feb5e619ae08506a4ff9a5d30d1cdb3c0aff30b6e7b41ad0d5 +size 143224 diff --git a/interpro_binding_site/consensus.joblib b/interpro_binding_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..cdde6e6dd7f574ad64fe044b5e79723294030ea8 --- /dev/null +++ b/interpro_binding_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:92c355480424b326ee7ceb13ddd861e33c3867dd3c9d4f220db12ee93126c7a7 +size 86911 diff --git a/interpro_binding_site/df_merge.tsv b/interpro_binding_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_binding_site/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_binding_site/metrics.json b/interpro_binding_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..395cf2b63ffa636bcda4735a872ced46dd2145a8 --- /dev/null +++ b/interpro_binding_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 4.818181818181818 +} \ No newline at end of file diff --git a/interpro_binding_site/paths.json b/interpro_binding_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..351bc19b4f37a1a0a8d63ddfb0aedd55df0bc387 --- /dev/null +++ b/interpro_binding_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/interpro_binding_site/result.tsv b/interpro_binding_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..1af2325c2f402a788dc07d12ec05e007e6317b96 --- /dev/null +++ b/interpro_binding_site/result.tsv @@ -0,0 +1,6 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +IQ motif, EF-hand binding site [IPR000048] 0.6652244262467623 1.8963714571273764 0.0579109434005784 0.8603520233863037 0.1061700629010605 12 P35579,Q15051,Q86VI3,P35580 4 +Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.4498764075803242 0.3854939649025412 0.6998714769571315 1.0 0.8131397172772707 2 P34897 1 +EF-Hand 1, calcium-binding site [IPR018247] 0.2997609096928363 0.3584188334007385 0.72002989958699 1.0 0.8131397172772707 41 Q9BRK5,Q02818,P12814,Q14257,Q9NZM3,Q9Y680,O43707,Q9BPX6,Q9H223,Q13813,P80303 11 +Peptidase M16, zinc-binding site [IPR001431] 0.4418322814277614 0.3328891964384092 0.7392179247975188 1.0 0.8131397172772707 5 P22695 1 +Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917] 0.3724251579236426 0.1769644282040973 0.8595363307241843 1.0 0.886396841059315 2 O75600 1 diff --git a/interpro_binding_site/selections.json b/interpro_binding_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fe7922b9442b3343e5b4282c71bedf3d31c4974c --- /dev/null +++ b/interpro_binding_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit I, copper-binding site [IPR023615]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT1", "AKT2", "APEX1", "APOBEC3C", "ARG2", "AURKA", "AURKB", "BPNT1", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDC42BPB", "CDC7", "CDK1", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CETN2", "CHUK", "COX1", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CYB5B", "DBT", "DLAT", "DLST", "DST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GSK3A", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "ITSN2", "LETM1", "MACF1", "MAP2K1", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARK2", "MCCC1", "MCFD2", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NEK3", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PDHX", "PDP1", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA2", "PRKACA", "PRKCD", "PRKCSH", "PSAT1", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "STK26", "STK4", "TKT", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1"], "leading_proteins": ["ACTN1", "ACTN4", "EHD4", "FKBP7", "GCAT", "IQCB1", "IQGAP3", "ITSN2", "MICU1", "MYH10", "MYH9", "NUCB1", "NUCB2", "RCN2", "SDF4", "SHMT2", "SPTAN1", "UQCRC2"]} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/idx2term.json b/interpro_conserved_site/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..da869fb319ca58624809388d34a600a8f29051cf --- /dev/null +++ b/interpro_conserved_site/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Intermediate filament protein, conserved site [IPR018039]", "2": "Zinc finger, RING-type, conserved site [IPR017907]"} \ No newline at end of file diff --git a/interpro_conserved_site/advanced/plot_0.png b/interpro_conserved_site/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..eafc8ec3d171b1e4e4aa915875223a9df9beb68f --- /dev/null +++ b/interpro_conserved_site/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:5929ca93ab6c9b7c289ef6c91886f46d5dc9792c71e740847be0ac53b82c396e +size 195430 diff --git a/interpro_conserved_site/advanced/plot_1.png b/interpro_conserved_site/advanced/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..b2052f9c2fdcc89365fdd709f49fa26871029543 --- /dev/null +++ b/interpro_conserved_site/advanced/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:22b2e87cc2eb66d08c9d920f9b758cd61e871202f93ac8c48fc0bca7810ee225 +size 192510 diff --git a/interpro_conserved_site/advanced/plot_2.png b/interpro_conserved_site/advanced/plot_2.png new file mode 100644 index 0000000000000000000000000000000000000000..9e62d006db3bb862f44a6e5c996330e43b126b1b --- /dev/null +++ b/interpro_conserved_site/advanced/plot_2.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:96129cb177a8916e959ff5b2d48de815e8e65daee25c99748349001ce85dd30a +size 200184 diff --git a/interpro_conserved_site/basic/idx2term.json b/interpro_conserved_site/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..a80615bbd15a5428ce1ad7bb407bf0365c24f75a --- /dev/null +++ b/interpro_conserved_site/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome beta-type subunit, conserved site [IPR016050]", "1": "Intermediate filament protein, conserved site [IPR018039]", "2": "Zinc finger, RING-type, conserved site [IPR017907]", "3": "Ubiquitin specific protease, conserved site [IPR018200]", "4": "Zinc finger, PHD-type, conserved site [IPR019786]", "5": "Kinesin motor domain, conserved site [IPR019821]", "6": "Tr-type G domain, conserved site [IPR031157]"} \ No newline at end of file diff --git a/interpro_conserved_site/basic/plot_0.png 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sha256:e66dfafa632be4ecc3a47a7c177964701460025156ee17eb24e146b53ed33126 +size 153573 diff --git a/interpro_conserved_site/basic/plot_5.png b/interpro_conserved_site/basic/plot_5.png new file mode 100644 index 0000000000000000000000000000000000000000..6bb162c0ca67f6afd80bb51b5fdb39381be3106d --- /dev/null +++ b/interpro_conserved_site/basic/plot_5.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:246411c48d5ff70f84e23c5a0dcfdb38a28f342b8e20a63b21f5a1cb85c95d69 +size 153087 diff --git a/interpro_conserved_site/basic/plot_6.png b/interpro_conserved_site/basic/plot_6.png new file mode 100644 index 0000000000000000000000000000000000000000..1530b52c959644089ad2dc193dd1b9aa7480877f --- /dev/null +++ b/interpro_conserved_site/basic/plot_6.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3777759afadf4b80cee9d320c6ed967d53ce34031faeba25f1f0253a33063002 +size 142784 diff --git a/interpro_conserved_site/consensus.joblib b/interpro_conserved_site/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..63d28d6d01e961b924a380f468b24cd8ad3bf3d9 --- /dev/null +++ b/interpro_conserved_site/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:b297864a3aa65ec5cf84904ac3b50a4a2c66b0c1defc40636fb9caebbef7d732 +size 142356 diff --git a/interpro_conserved_site/df_merge.tsv b/interpro_conserved_site/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2c5ae019cc9aaf3d339c5d5113d9547dc27f128d --- /dev/null +++ b/interpro_conserved_site/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome beta-type subunit, conserved site [IPR016050] 5 8 2.5035869349846447 0.0122941472916477 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 0.0461123069087121 0.0038356556834428 3.59582749836129e-08 2.285385949037992e-06 +Intermediate filament protein, conserved site [IPR018039] 6 8 2.2264216745267045 0.0259859500108001 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 1.0 1.0 1.0 0.0007750266814789 0.0001445816257764 +Zinc finger, RING-type, conserved site [IPR017907] 6 17 2.044123597758694 0.0409413384740326 4.609223300970874 14.776699029126211 -0.045326225777209 0.5577732895844865 3.238903742779499 4.550007017672923 0.8841385018499901 0.2924846286854669 1.0 0.3805737292783386 0.2496840539684075 0.4418071915292876 0.2204596086552104 diff --git a/interpro_conserved_site/metrics.json b/interpro_conserved_site/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..abb431da1da9244fc5603a389269a64de57fbc90 --- /dev/null +++ b/interpro_conserved_site/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 291, + "title": "Average number of proteins per term", + "value": 2.821305841924399 +} \ No newline at end of file diff --git a/interpro_conserved_site/paths.json b/interpro_conserved_site/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..1448f6dd59bcdda62f7bda5755af57871cb1aaab --- /dev/null +++ b/interpro_conserved_site/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/interpro_conserved_site/result.tsv b/interpro_conserved_site/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3bf886c9e42104a0b830185505ed9e4d93c26131 --- /dev/null +++ b/interpro_conserved_site/result.tsv @@ -0,0 +1,46 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.8944185520226009 0.026041974727335 2 P05067 1 +Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.8944185520226009 0.026041974727335 2 P05067 1 +Proteinase inhibitor I2, Kunitz, conserved site [IPR020901] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.8944185520226009 0.026041974727335 2 P05067 1 +Proteasome beta-type subunit, conserved site [IPR016050] 0.8781082600579835 2.5035869349846447 0.0122941472916477 0.972670007085706 0.0365060904272398 8 P28074,P20618,P28072,Q99436,P49721 5 +Glycoside hydrolase, family 29, conserved site [IPR018526] 0.9376544905245802 2.4524158380675924 0.0141900569845192 0.9843750185380552 0.041293065824951 2 Q9BTY2 1 +Sugar transporter, conserved site [IPR005829] 0.9209008514144446 2.382742284792231 0.0171842197940224 0.993552561686218 0.0442531677881461 2 Q7L0J3 1 +Intermediate filament protein, conserved site [IPR018039] 0.8127410216384736 2.2264216745267045 0.0259859500108001 0.999529586831442 0.0600151702630384 8 P07197,P20700,P08670,Q03252,P02545,P07196 6 +Tetraspanin, conserved site [IPR018503] 0.8437242515792335 2.0554837378839133 0.0398323047989266 0.9999927053710204 0.0822070971382102 2 O60637 1 +Zinc finger, RING-type, conserved site [IPR017907] 0.6132138879553305 2.044123597758694 0.0409413384740326 0.999994788712543 0.0830114814155882 17 P19474,O15344,Q14527,O60858,Q13049,Q99590 6 +Aldehyde dehydrogenase, cysteine active site [IPR016160] 0.7432919459255365 1.9222331927509773 0.0545764219724098 0.9999999192224186 0.1018060179100722 8 P30837 1 +ABC transporter-like, conserved site [IPR017871] 0.6369280544691495 1.883524096952764 0.0596293773665668 0.999999983016606 0.1071120297140181 14 O75027 1 +Sulfatase, conserved site [IPR024607] 0.8019774787146375 1.8744044950530183 0.0608746944154297 0.9999999884508224 0.1086781354287732 2 P15586 1 +DNA mismatch repair, conserved site [IPR014762] 0.7962098324636051 1.8491848649769544 0.064431123412586 0.9999999961713308 0.113633072200379 2 Q86VD7 1 +Ribosomal protein L24e, conserved site [IPR023442] 0.7267234276297689 1.5421960385014823 0.1230259624634679 1.0 0.1874374611354407 2 Q9UHA3 1 +Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184] 0.7151881351277088 1.4908027346554398 0.1360132936031362 1.0 0.2019381042781256 2 P17301 1 +Immunoglobulin/major histocompatibility complex, conserved site [IPR003006] 0.7922584307451964 1.4609668600192207 0.1440245363201653 1.0 0.2083722811028403 3 P30511 1 +Guanylate kinase, conserved site [IPR020590] 0.6410160114538123 1.3637728491337833 0.1726390679944844 1.0 0.2403730563942343 7 Q14168,Q8N3R9,O14936 3 +Sterol reductase, conserved site [IPR018083] 0.7540594951154558 1.3108306991355558 0.1899149683364818 1.0 0.2606851688014915 3 Q9UBM7 1 +Oxysterol-binding protein, conserved site [IPR018494] 0.6564318205937275 1.2701643146512247 0.2040261061161021 1.0 0.2774373685971296 6 Q9H4L5 1 +Cyclic nucleotide-binding, conserved site [IPR018488] 0.6127437517165552 1.0348243790193694 0.3007509354673354 1.0 0.3855441507532802 2 P13861 1 +Ubiquitin specific protease, conserved site [IPR018200] 0.4575687012480521 1.013982684372968 0.3105910148068098 1.0 0.3946811585536317 16 Q96K76,Q86UV5,Q8NB14,Q93009,Q9UPT9 5 +Aldehyde dehydrogenase, glutamic acid active site [IPR029510] 0.5401741561768885 0.990788793807095 0.3217887223698552 1.0 0.4053702086996877 8 P30837 1 +Dynamin, GTPase region, conserved site [IPR019762] 0.6675241220797068 0.972735839726386 0.3306846078612757 1.0 0.4147811245156518 3 Q9UQ16 1 +Ras GTPase-activating protein, conserved site [IPR023152] 0.6615868923671951 0.9498858356156592 0.3421702647542037 1.0 0.4247420235235584 3 Q86VI3 1 +Methylthiotransferase, conserved site [IPR020612] 0.5773139247459417 0.8806246688788618 0.3785210019820666 1.0 0.4643975688629024 2 Q96SZ6 1 +Zinc finger, PHD-type, conserved site [IPR019786] 0.4037265128441828 0.8264754918716694 0.4085344150559225 1.0 0.495347978255306 18 Q9BZ95,Q9UIG0,Q9NRL2,O96028,Q9Y2K7,Q14839,Q96L73 7 +Actinin-type actin-binding domain, conserved site [IPR001589] 0.4418220474741786 0.7994428336658261 0.4240336818659238 1.0 0.5057123009138682 14 P12814,P46939,O43707 3 +Cadherin conserved site [IPR020894] 0.5989263330922214 0.7887378743115694 0.4302652266651807 1.0 0.5110120253690245 4 P19022,O60245 2 +Syntaxin/epimorphin, conserved site [IPR006012] 0.4980082103333684 0.7313643844340051 0.4645566134863705 1.0 0.5407438980981354 7 O15400,O43752,O60499 3 +Bromodomain, conserved site [IPR018359] 0.4303580780549267 0.6472532589339539 0.5174680470581476 1.0 0.5975523876742895 11 Q9UIF9,Q15059,Q9UIG0 3 +Ribosomal protein L24/L26, conserved site [IPR005825] 0.5166163141993885 0.6288673815387849 0.5294358822159719 1.0 0.6089558961456436 2 Q96A35 1 +Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326] 0.4907992309804909 0.5293945452609559 0.5965317813531499 1.0 0.6761699257213174 2 P29692 1 +Mini-chromosome maintenance, conserved site [IPR018525] 0.4693010950786808 0.504919649999497 0.6136152720499768 1.0 0.6894287419557654 6 Q14566 1 +Kinesin motor domain, conserved site [IPR019821] 0.3708281256965587 0.3953577795069776 0.6925788633516896 1.0 0.7692383558600827 13 Q9Y496,Q02241,P52732,Q14807,O95239,P33176 6 +Ribosomal protein L13, conserved site [IPR023563] 0.4507003570447634 0.3881942290564076 0.6978723035187699 1.0 0.7721704955283728 2 Q9BYD1 1 +Ribosomal protein L30, conserved site [IPR018038] 0.448777808294416 0.3819074523331101 0.702530012370373 1.0 0.7729138146489972 2 Q6DKI1 1 +Phosphorylase pyridoxal-phosphate attachment site [IPR035090] 0.4482285086514592 0.3801201580139388 0.7038562229621452 1.0 0.7729138146489972 2 P06737 1 +Ribosomal protein S5, N-terminal, conserved site [IPR018192] 0.4246086240043892 0.3072188875120454 0.7586767700938803 1.0 0.8266726934554218 2 P82675 1 +4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900] 0.4387362637362655 0.2266147751880298 0.8207233022301039 1.0 0.8747423142207802 3 P21912,O00217 2 +ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629] 0.3005712471075765 0.2172926893052138 0.8279802540855181 1.0 0.8761536506868574 20 Q8N8A6,Q9UHI6 2 +Tr-type G domain, conserved site [IPR031157] 0.3758592246356997 0.2106481963729465 0.8331618007620767 1.0 0.8784423334121896 6 Q05639,Q8N442,P49411,P13639,Q96RP9 5 +HMG box A DNA-binding domain, conserved site [IPR017967] 0.4064547698258781 0.1619469890553382 0.8713475992727306 1.0 0.9094910699057096 3 P26583 1 +Lysosome-associated membrane glycoprotein, conserved site [IPR018134] 0.3490799230980458 0.1336870380355171 0.893650055299499 1.0 0.922933704169298 2 P11279 1 +Chromo domain, conserved site [IPR023779] 0.3433205057724071 0.1065768086237846 0.9151247178118724 1.0 0.9376806087438552 5 O14646,Q13185,P45973,Q9HC52 4 +Clathrin adaptor, mu subunit, conserved site [IPR018240] 0.3465237702665641 0.0897039998475197 0.928522437340837 1.0 0.94807027812696 4 Q9BXS5,Q9Y2T2,Q96CW1 3 diff --git a/interpro_conserved_site/selections.json b/interpro_conserved_site/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..bbe93c4bf012098095422600811272224d9920c7 --- /dev/null +++ b/interpro_conserved_site/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-2-macroglobulin, conserved site [IPR019742]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Anion exchange, conserved site [IPR018241]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Deoxyribonuclease, TatD-related, conserved site [IPR018228]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FHF complex subunit HOOK interacting protein, KELAA motif [IPR045668]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "Fibrillarin, conserved site [IPR020813]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 2, conserved site [IPR023230]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "Hydroxymethylglutaryl-CoA reductase, class I/II, conserved site [IPR023076]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Integrin alpha chain, C-terminal cytoplasmic region, conserved site [IPR018184]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Pyridoxamine 5'-phosphate oxidase, conserved site [IPR019740]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Uncharacterised protein family UPF0029, Impact, conserved site [IPR020569]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABR", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "AP3S1", "AP4M1", "APEX1", "APLP2", "APP", "ARHGEF7", "ARIH2", "ARRB2", "ATAD1", "ATAD2", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD320", "CDH2", "CDK5RAP1", "CDKAL1", "CENPE", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CLGN", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX6", "DHCR7", "DHFR", "DHRS4", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIS3", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DST", "DTYMK", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FAM160B2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FIGNL1", "FLNA", "FLNB", "FLNC", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GALNS", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GGPS1", "GLA", "GLB1", "GLO1", "GMPPA", "GMPPB", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "GUSB", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLA-B", "HLA-F", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "IQGAP1", "IQGAP2", "IQGAP3", "ITGA2", "ITGAV", "IVD", "KATNA1", "KDM2A", "KDSR", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "LAMP1", "LAMP2", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MOCS1", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSD3", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT12", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PAX6", "PBRM1", "PCDH7", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PEX6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF14", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "PNPO", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBBP7", "RCL1", "RDH13", "RDX", "RIDA", "RIOK2", "RNF14", "RNF2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC25A42", "SLC27A4", "SLC2A1", "SLC4A2", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPAST", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAP1", "TATDN1", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMX1", "TMX3", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN3", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UBFD1", "UHRF1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR5", "WDR61", "WDR7", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2", "ZMYND8"], "leading_proteins": ["ABCB7", "ACTN1", "ACTN4", "ALDH1B1", "AP1M1", "AP2M1", "AP3M1", "APP", "BAZ1A", "BAZ1B", "BAZ2A", "BRD3", "CASK", "CBX3", "CBX5", "CBX8", "CDH2", "CDK5RAP1", "CHD1", "CHD4", "DDX20", "DDX51", "DHCR7", "DNM3", "EEF1A2", "EEF1D", "EEF2", "FUCA2", "GFM1", "GNS", "GUF1", "HLA-F", "HLTF", "HMGB2", "IQGAP3", "ITGA2", "KDM2A", "KIF11", "KIF22", "KIF23", "KIF3A", "KIF4A", "KIF5B", "LAMP1", "LMNA", "LMNB1", "LMNB2", "MCM6", "MID1", "MPP2", "MPP5", "MRPL13", "MRPL24", "MRPS5", "NDUFS8", "NEFL", "NEFM", "NSD1", "NSD2", "NSD3", "OSBPL3", "PCDH7", "PRKAR2A", "PSMB1", "PSMB2", "PSMB5", "PSMB6", "PSMB7", "PYGL", "RPL7L1", "RSL24D1", "SCAF11", "SDHB", "SLC25A42", "STX10", "STX6", "STX7", "SV2A", "TRIM13", "TRIM21", "TRIM32", "TSPAN3", 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0000000000000000000000000000000000000000..0db08a601a492ad606176f7e8a47c990974ef56e --- /dev/null +++ b/interpro_domain/basic/plot_9.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9a4f01eb87598e7ada116446b234289d0e4e0129334f580d8488662c6b54e2df +size 136486 diff --git a/interpro_domain/consensus.joblib b/interpro_domain/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..3c19d7d9326f6d4e1f177e6a5382f015f23424dd --- /dev/null +++ b/interpro_domain/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:3264119624eae0422a7eeaaae237c712e806c29ff00d5776227dd40b3756cdca +size 769232 diff --git a/interpro_domain/df_merge.tsv b/interpro_domain/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..646742c897ddc0543aa864e711a29d2c8359725b --- /dev/null +++ b/interpro_domain/df_merge.tsv @@ -0,0 +1,9 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Major facilitator superfamily domain [IPR020846] 3 7 2.447068916309711 0.014402329744124 1.8883495145631068 4.121359223300971 0.8776223597987594 0.2728824130413255 1.233496960525634 1.4580976091979958 1.2936014196902064 0.266909732326598 1.0 0.0003636173209342 0.0001744894487537 0.0055331858379351 0.0138780941766985 +Intermediate filament, rod domain [IPR039008] 6 8 2.2264216745267045 0.0259859500108001 4.060679611650485 7.546116504854369 0.7869831563787604 0.2926647109331939 1.9153715257926656 0.8924219614624045 1.3691577499316503 0.3120813432784052 1.0 1.0 1.0 0.0017174581383874 0.0004920431328091 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 3 7 2.188409642667134 0.0286397765197126 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 1.0 0.0550816697898294 0.0055563644779973 0.0025975272437437 0.0020033682110678 +B-box-type zinc finger [IPR000315] 4 9 2.145058641348916 0.0319481586742338 2.150485436893204 6.019417475728155 0.1378906185367559 0.5071478683401887 1.8477682043932235 1.6174448417195804 0.9644160769127244 0.3051430714909308 1.0 0.1484538203623246 0.0412617301526311 0.0479498850625808 0.0231294135439989 +Immunoglobulin-like domain [IPR007110] 5 17 2.0563149721731326 0.0397521660613104 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 3.173316973839475 1.1756568118942026 0.3233613924696422 1.0 1.0 1.0 0.7615373729224523 0.8065516719630483 +Zinc finger, RING-type [IPR001841] 10 31 2.0494609122635765 0.0404170662457008 7.83252427184466 26.79368932038835 -0.1911762841470096 0.5719525680476609 4.456217477926311 6.9060026641091055 0.8588565107477053 0.2983783106382085 1.0 0.577581418089764 0.2475305235196633 0.4439350318504531 0.3859468776573329 +ABC transporter type 1, transmembrane domain [IPR011527] 1 10 2.029672406444673 0.042389849524596 2.3689320388349513 6.349514563106796 0.6640264147492347 0.3307390797434538 1.7803691733569 2.1393617497725477 1.1694677427725269 0.279101120079799 1.0 0.0683810764565047 0.1336663515258769 0.0495157384890535 0.16360549489043 +FAD/NAD(P)-binding domain [IPR023753] 1 6 2.0165450132388187 0.043743016240543 1.305825242718447 4.980582524271845 0.3254034663776002 0.5017462024465073 1.2360542642688364 0.4721482103218573 0.9364120623905048 0.2987345213731214 1.0 0.0011617774889038 0.0046590638338273 0.0276231155809849 0.0140894483762481 diff --git a/interpro_domain/metrics.json b/interpro_domain/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..45f4d36ec88b773bf62f8626a3bca941d2944ba5 --- /dev/null +++ b/interpro_domain/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 2792, + "title": "Average number of proteins per term", + "value": 2.245702005730659 +} \ No newline at end of file diff --git a/interpro_domain/paths.json b/interpro_domain/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..be203cd731d3dc90bd813113a092a228e6a09277 --- /dev/null +++ b/interpro_domain/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/interpro_domain/result.tsv b/interpro_domain/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c88c5d7c7ae24ce82a7ac9786865e906839db7e6 --- /dev/null +++ b/interpro_domain/result.tsv @@ -0,0 +1,326 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Amyloidogenic glycoprotein, heparin-binding [IPR015849] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.9999999995716392 0.0201764697924588 2 P05067 1 +Pancreatic trypsin inhibitor Kunitz domain [IPR002223] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.9999999995716392 0.0201764697924588 2 P05067 1 +Amyloidogenic glycoprotein, extracellular [IPR008154] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.9999999995716392 0.0201764697924588 2 P05067 1 +Amyloidogenic glycoprotein, copper-binding [IPR011178] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.9999999995716392 0.0201764697924588 2 P05067 1 +Amyloidogenic glycoprotein, E2 domain [IPR024329] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.9999999995716392 0.0201764697924588 2 P05067 1 +Beta-amyloid precursor protein C-terminal [IPR019543] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.9999999995716392 0.0201764697924588 2 P05067 1 +Phospholipase D/Transphosphatidylase [IPR001736] 0.9810491623180444 2.630555819409903 0.0085245369337778 0.9999999999583838 0.02176143946085 2 Q8N2A8 1 +Galactosyltransferase, N-terminal [IPR027995] 0.9689645701730294 2.5812851549829428 0.0098433238508726 0.9999999999989876 0.0242778800279472 2 O60512 1 +Galactosyltransferase, C-terminal [IPR027791] 0.9689645701730294 2.5812851549829428 0.0098433238508726 0.9999999999989876 0.0242778800279472 2 O60512 1 +Citron homology (CNH) domain [IPR001180] 0.9582532271354024 2.5373952727398383 0.0111680777374676 0.999999999999976 0.0268572549896724 2 Q8WUH2 1 +Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564] 0.9417742378467436 2.4694722592405576 0.0135312509547218 1.0 0.031051645434528 2 Q13505 1 +Metaxin, glutathione S-transferase domain [IPR033468] 0.9417742378467436 2.4694722592405576 0.0135312509547218 1.0 0.031051645434528 2 Q13505 1 +Alpha-L-fucosidase, C-terminal [IPR031919] 0.9376544905245802 2.4524158380675924 0.0141900569845192 1.0 0.032315366313848 2 Q9BTY2 1 +Major facilitator superfamily domain [IPR020846] 0.8939318398995872 2.447068916309711 0.014402329744124 1.0 0.0326977603218662 7 Q7L0J3,Q6NT16,P53985 3 +ROCK, Rho binding domain [IPR015008] 0.9090909090909094 2.3333297202576393 0.0196308467414296 1.0 0.0418072647613056 2 O75116 1 +FAD linked oxidase, N-terminal [IPR006094] 0.8948091183740704 2.2732480550852796 0.0230112358918961 1.0 0.0474500521493161 2 Q15392 1 +FAD-binding domain, PCMH-type [IPR016166] 0.8948091183740704 2.2732480550852796 0.0230112358918961 1.0 0.0474500521493161 2 Q15392 1 +Ribosome receptor lysine/proline rich [IPR007794] 0.8928865696237291 2.265132996677228 0.0235045193075753 1.0 0.0483011175053918 2 Q86UP2 1 +DOCKER domain [IPR027357] 0.890964020873384 2.2570115318948676 0.0240073541977161 1.0 0.0491051523223615 2 Q14185 1 +C2 DOCK-type domain [IPR027007] 0.890964020873384 2.2570115318948676 0.0240073541977161 1.0 0.0491051523223615 2 Q14185 1 +Zinc finger, B-box, chordata [IPR020457] 0.8901400714089508 2.2535289459355514 0.024225817746458 1.0 0.0493711555825626 2 P19474 1 +Intermediate filament, rod domain [IPR039008] 0.8127410216384736 2.2264216745267045 0.0259859500108001 1.0 0.0519719000216003 8 P07197,P20700,P08670,Q03252,P02545,P07196 6 +PA domain [IPR003137] 0.8835484756934887 2.2256260950045164 0.026039236797265 1.0 0.0520411948016922 2 Q8TCT8 1 +Cytochrome b5-like heme/steroid binding domain [IPR001199] 0.8310604024419772 2.188409642667134 0.0286397765197126 1.0 0.0559771204927229 7 Q8WUJ1,Q9UMX5,O15173 3 +GRIP domain [IPR000237] 0.8742103817632516 2.185969538668437 0.0288178339914488 1.0 0.0562653094434442 2 Q96CN9 1 +Syntaxin 6, N-terminal [IPR015260] 0.871738533369951 2.1754473758364252 0.0295966075657831 1.0 0.057424411621728 2 O60499 1 +Isochorismatase-like [IPR000868] 0.8662455369403983 2.152027854172158 0.0313951606208242 1.0 0.0603271083643092 2 Q96CN7 1 +B-box-type zinc finger [IPR000315] 0.7649803170110441 2.145058641348916 0.0319481586742338 1.0 0.0613474958861491 9 O60858,Q13049,P19474,O15344 4 +Gamma tubulin complex component protein, N-terminal [IPR041470] 0.8632243889041445 2.139125517370854 0.032425504311548 1.0 0.0620082246834534 2 Q96CW5 1 +Gamma tubulin complex component, C-terminal [IPR040457] 0.8632243889041445 2.139125517370854 0.032425504311548 1.0 0.0620082246834534 2 Q96CW5 1 +Immunoglobulin-like domain [IPR007110] 0.6152834476619371 2.0563149721731326 0.0397521660613104 1.0 0.0726448394011899 17 P10321,Q9BY67,P30511,P10586,Q9BX67 5 +Zinc finger, RING-type [IPR001841] 0.5383548621092056 2.0494609122635765 0.0404170662457008 1.0 0.0735142989954376 31 Q9Y4X5,P19474,O15344,Q14527,O60858,P14373,O96028,O75592,Q13049,Q99590 10 +COP9 signalosome complex subunit 7, helix I [IPR041481] 0.8379566053282057 2.030626309153724 0.0422929167936678 1.0 0.076083649283454 2 Q9H9Q2 1 +ABC transporter type 1, transmembrane domain [IPR011527] 0.7114341493304953 2.029672406444673 0.042389849524596 1.0 0.0762089245799562 10 O75027 1 +FAD/NAD(P)-binding domain [IPR023753] 0.8349768836094977 2.0165450132388187 0.043743016240543 1.0 0.0781259759622696 6 P00390 1 +Protein Kinase B, pleckstrin homology domain [IPR039026] 0.8338368580060412 2.012838639472091 0.0441316075126758 1.0 0.0784811771817777 2 P31751 1 +MRH domain [IPR044865] 0.905615302303393 1.990866266504577 0.0464955916996723 1.0 0.0816964707523506 4 P20645 1 +OCRE domain [IPR041591] 0.9211985816350255 1.9606106154783505 0.049924463101449 1.0 0.0865233401485075 3 P98175 1 +Prenylcysteine lyase [IPR010795] 0.8214776160395486 1.9593168783682715 0.0500756883132607 1.0 0.0865400424777289 2 Q9UHG3 1 +STAG [IPR013721] 0.8209283163965932 1.956932694432007 0.0503553820364595 1.0 0.0867317869499043 2 Q8WVM7 1 +Stromalin conservative domain [IPR020839] 0.8209283163965932 1.956932694432007 0.0503553820364595 1.0 0.0867317869499043 2 Q8WVM7 1 +HIT-like domain [IPR011146] 0.8192804174677242 1.9497774059770312 0.0512026556526028 1.0 0.0879199351673229 2 Q9NQE9 1 +Amino acid permease/ SLC12A domain [IPR004841] 0.8170832188959074 1.94023066607398 0.052351663226561 1.0 0.0897273442164263 2 P55011 1 +SLC12A transporter, C-terminal [IPR018491] 0.8170832188959074 1.94023066607398 0.052351663226561 1.0 0.0897273442164263 2 P55011 1 +Lamin tail domain [IPR001322] 0.9123626373626376 1.9269164766198033 0.0539900397723283 1.0 0.0918587392104452 3 P02545,Q03252 2 +Zinc finger, ZZ-type [IPR000433] 0.8135127712166959 1.9247018500713953 0.0542666689225133 1.0 0.0921062540271402 2 P46939 1 +EF-hand, Ca insensitive [IPR014837] 0.9085164835164838 1.9122204870879596 0.0558479194213807 1.0 0.0938756116944582 3 P12814,Q13813 2 +CYRIA/CYRIB, Rac1 binding domain [IPR009828] 0.9057692307692312 1.9017125753450728 0.0572087409386341 1.0 0.0954162513146156 3 Q96F07,Q9NUQ9 2 +ERAP1-like C-terminal domain [IPR024571] 0.8816553070273664 1.8988102017939064 0.0575894353709713 1.0 0.0957081568784238 4 Q9UIQ6,P55786 2 +Fibronectin type II domain [IPR000562] 0.8041746772864553 1.8839996919566135 0.0595650171367001 1.0 0.0980575046259828 2 P11717 1 +ABC transporter-like, ATP-binding domain [IPR003439] 0.6369280544691495 1.883524096952764 0.0596293773665668 1.0 0.0981056108470563 14 O75027 1 +Sulfatase, N-terminal [IPR000917] 0.8019774787146375 1.8744044950530183 0.0608746944154297 1.0 0.09950945363459 2 P15586 1 +Myosin, N-terminal, SH3-like [IPR004009] 0.8355703414377414 1.8621789463921528 0.062577871014293 1.0 0.1015798929487826 5 P35579,P35580 2 +EB1, C-terminal [IPR004953] 0.7978577313924721 1.8563951936210343 0.0633972493183305 1.0 0.1023742742028796 2 Q15555 1 +Ubiquitin conjugation factor E4, core [IPR019474] 0.797583081570994 1.8551937326634695 0.0635685663471181 1.0 0.1025915822203201 2 O95155 1 +Pleckstrin homology domain [IPR001849] 0.5114533859681984 1.8504452153997044 0.0642494072286885 1.0 0.1032725071862397 31 Q9H4L5,Q9NZM3,Q96TA1,Q96JJ3,Q13464,Q6WCQ1,O75116,Q01082,P31751,Q9Y5S2,P11274 11 +Butyrophylin-like, SPRY domain [IPR003879] 0.8319672333594973 1.8478235850851696 0.0646278678337743 1.0 0.1035826676187704 5 P19474,O15344 2 +SPRY-associated [IPR006574] 0.8319672333594973 1.8478235850851696 0.0646278678337743 1.0 0.1035826676187704 5 P19474,O15344 2 +Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337] 0.7882449876407568 1.814282847182926 0.0696341909546212 1.0 0.1101522159463469 2 O43390 1 +Leucine-rich repeat N-terminal domain [IPR000372] 0.7868717385333669 1.8082566914049651 0.0705665589485566 1.0 0.1112489173260136 2 Q13641 1 +Cysteine-rich flanking region, C-terminal [IPR000483] 0.7868717385333669 1.8082566914049651 0.0705665589485566 1.0 0.1112489173260136 2 Q13641 1 +TRAM/LAG1/CLN8 homology domain [IPR006634] 0.8568287991206234 1.802660965601709 0.0714414760500021 1.0 0.1123623737615492 4 Q96G23,P27544,Q96CP7 3 +Intermediate filament head, DNA-binding domain [IPR006821] 0.8565539983511792 1.801592563363199 0.071609532156863 1.0 0.1123855052175163 4 P07197,P08670,P07196 3 +WSTF/Acf1/Cbp146 [IPR013136] 0.7841252403185923 1.796196981600162 0.0724631946120015 1.0 0.1134906982007212 2 Q9UIG0 1 +Amine oxidase [IPR002937] 0.8775662088458527 1.7933391460216306 0.0729187116077847 1.0 0.1140554861674705 3 Q8NB78 1 +L27 domain [IPR004172] 0.8150128151352414 1.780042291612069 0.0750690397004245 1.0 0.1161727338830375 5 Q14168,Q8N3R9,O14936 3 +L27 domain, C-terminal [IPR014775] 0.8150128151352414 1.780042291612069 0.0750690397004245 1.0 0.1161727338830375 5 Q14168,Q8N3R9,O14936 3 +Fragile X-related 1 protein, C-terminal region 1 [IPR032172] 0.7750617962098307 1.756331709569811 0.079031785905101 1.0 0.120117989247165 2 P51114 1 +Myosin tail [IPR002928] 0.8437023489107003 1.7515298551471414 0.079854683289265 1.0 0.1211708020345804 4 P35579,P35580 2 +Fibronectin type III [IPR003961] 0.7230994613683847 1.72685524601345 0.0841936636941071 1.0 0.1265170662184861 7 Q15375,O15344,P10586 3 +Class II aldolase/adducin N-terminal [IPR001303] 0.7616039549574273 1.6969549062952731 0.0897051862312885 1.0 0.1323767864470177 2 Q9UEY8 1 +Immunoglobulin C1-set [IPR003597] 0.7903666890560199 1.6808650448361662 0.0927891309379547 1.0 0.1358170408808121 5 P30511,P10321 2 +HR1 rho-binding domain [IPR011072] 0.7895103293360026 1.6774061089560215 0.0934630956026365 1.0 0.1366224936767336 5 O75116,Q96RU3 2 +U-box domain [IPR003613] 0.7101649408597805 1.6702160964209571 0.0948766164396766 1.0 0.1383465995887925 7 P19474 1 +Diacylglycerol kinase, catalytic domain [IPR001206] 0.7525405108486625 1.656852775429982 0.0975492440233196 1.0 0.1408988563440809 2 Q9NRA0 1 +Myosin head, motor domain [IPR001609] 0.6771661526866953 1.6239850621670917 0.1043789966648351 1.0 0.1485352490765646 8 P35579,P35580 2 +Rab-binding domain FIP-RBD [IPR019018] 0.741279868168083 1.6069142726023324 0.1080731750392103 1.0 0.1526025082831277 2 Q8IUD2 1 +BTB/POZ domain [IPR000210] 0.7714951083490369 1.604455714263612 0.1086136386510876 1.0 0.1530788890024415 5 Q4G0X4 1 +P-type ATPase, haloacid dehalogenase domain [IPR044492] 0.7327228967970489 1.5935355599975791 0.1110400975612098 1.0 0.1554784114297381 6 P16615 1 +MHC class I alpha chain, alpha1 alpha2 domains [IPR001039] 0.801596951340724 1.586302900798722 0.1126706146014386 1.0 0.1571790190535362 4 P30511,P10321 2 +RING-type zinc-finger, LisH dimerisation motif [IPR027370] 0.801101215038831 1.584347771966071 0.113114600164639 1.0 0.1576714746179092 4 O60858,Q13049 2 +Translation initiation factor IF- 2, domain 3 [IPR023115] 0.7322164240593204 1.5666376314022687 0.1171994165517571 1.0 0.1624730739883346 2 P46199 1 +Peptidase M1, membrane alanine aminopeptidase [IPR014782] 0.7242639521483516 1.5579162412450842 0.1192531046464844 1.0 0.1640170779177263 6 Q9UIQ6,P55786 2 +Aminopeptidase N-like , N-terminal domain [IPR045357] 0.7242639521483516 1.5579162412450842 0.1192531046464844 1.0 0.1640170779177263 6 Q9UIQ6,P55786 2 +RecF/RecN/SMC, N-terminal [IPR003395] 0.7239483090459051 1.556585627333624 0.1195688983674228 1.0 0.1642011874620917 6 Q9UQE7,Q8IY18,O95347,Q9NTJ3,Q14683 5 +SPRY domain [IPR003877] 0.6079182396567849 1.5207501202792553 0.1283225559075478 1.0 0.1739206680067347 10 P19474,O15344 2 +B30.2/SPRY domain [IPR001870] 0.6079182396567849 1.5207501202792553 0.1283225559075478 1.0 0.1739206680067347 10 P19474,O15344 2 +Integrin alpha-2 [IPR013649] 0.7151881351277088 1.4908027346554398 0.1360132936031362 1.0 0.1823087449543717 2 P17301 1 +Zinc finger, RanBP2-type [IPR001876] 0.647610944119114 1.4884149675770164 0.1366414917289451 1.0 0.1829750814902709 8 P98175,P35637,P49792,P52756,Q01844 5 +HOOK, N-terminal [IPR043936] 0.794505494505495 1.469785816322602 0.1416197717927301 1.0 0.188286858497763 3 Q9UJC3,Q96ED9 2 +Hook, C-terminal [IPR008636] 0.794505494505495 1.469785816322602 0.1416197717927301 1.0 0.188286858497763 3 Q9UJC3,Q96ED9 2 +Sorting nexin, N-terminal [IPR005329] 0.7085965394122458 1.4614018522911705 0.1439051926804579 1.0 0.1907557765322647 2 O60749 1 +USP8 dimerisation domain [IPR015063] 0.7072232903048579 1.4552741722277198 0.1455933739089805 1.0 0.1925612031993716 2 O95630 1 +Immunoglobulin subtype 2 [IPR003598] 0.5840266680693564 1.435882316433427 0.1510358311848822 1.0 0.1991932171318806 11 Q13740,Q9BY67,O75147,P35613,P10586,Q9BX67 6 +Immunoglobulin subtype [IPR003599] 0.5840266680693564 1.435882316433427 0.1510358311848822 1.0 0.1991932171318806 11 Q13740,Q9BY67,O75147,P35613,P10586,Q9BX67 6 +NUC153 [IPR012580] 0.70118099423235 1.4283038781696935 0.1532044120775386 1.0 0.2018625382352467 2 Q9BSC4 1 +Dynamin, N-terminal [IPR045063] 0.6544449159846477 1.4236702270884083 0.1545419561659742 1.0 0.2033370130138548 7 O60313,Q9H223,Q9UQ16 3 +Dynamin-type guanine nucleotide-binding (G) domain [IPR030381] 0.6544449159846477 1.4236702270884083 0.1545419561659742 1.0 0.2033370130138548 7 O60313,Q9H223,Q9UQ16 3 +IPT domain [IPR002909] 0.6962372974457529 1.4062289005195312 0.1596561649125383 1.0 0.2093752994062034 2 Q96KP1 1 +ISWI, HAND domain [IPR015194] 0.6954133479813198 1.4025491716928022 0.1607513177976449 1.0 0.2106136458428084 2 P28370 1 +SLIDE domain [IPR015195] 0.6954133479813198 1.4025491716928022 0.1607513177976449 1.0 0.2106136458428084 2 P28370 1 +NSD, Cys-His rich domain [IPR041306] 0.7689560439560444 1.36941058390896 0.17087096770805 1.0 0.2230349424221017 3 O96028,Q96L73 2 +AWS domain [IPR006560] 0.7689560439560444 1.36941058390896 0.17087096770805 1.0 0.2230349424221017 3 O96028,Q96L73 2 +CARG-binding factor, N-terminal [IPR012956] 0.6844273551222149 1.35347749839602 0.1759031338403502 1.0 0.2293888601972246 2 Q14103 1 +Ras-associating (RA) domain [IPR000159] 0.7424254845352809 1.351818739037224 0.1764333079724123 1.0 0.2299728271984011 4 Q9Y4G8 1 +WHIM1 domain [IPR028942] 0.7418568795411637 1.3495580988656233 0.1771577723079751 1.0 0.2308093795071706 4 Q9UIF9,Q9UIG0 2 +Ribosomal protein L10e/L16 [IPR016180] 0.681406207085961 1.3399820432682468 0.1802511829141848 1.0 0.2345113246488369 2 P27635 1 +ATPase family AAA domain-containing protein 3, N-terminal [IPR021911] 0.6808569074430059 1.3375283871748371 0.1810502225546795 1.0 0.2354411836854519 2 Q5T9A4 1 +Acyltransferase, C-terminal domain [IPR032098] 0.6805822576215281 1.336301569478698 0.1814507237391014 1.0 0.2358521511543627 2 Q92604 1 +Zinc finger, MYM-type [IPR010507] 0.7583454622160313 1.3276856544156486 0.1842819746518942 1.0 0.2393094294084133 3 Q9UBW7 1 +MHC class I, alpha chain, C-terminal [IPR010579] 0.7561740982139153 1.3191464898696437 0.187120143450624 1.0 0.2425438442498339 3 P10321 1 +RBM1CTR [IPR012604] 0.6739906619060652 1.3068612321959736 0.1912598446493447 1.0 0.247564898591085 2 Q96E39 1 +Plectin/S10, N-terminal [IPR005326] 0.6723427629771994 1.2995025624598875 0.1937715146432248 1.0 0.2506997538850249 2 P46783 1 +Guanylate kinase-like domain [IPR008144] 0.5831743069705506 1.2875728764799774 0.1978946860970023 1.0 0.2556788355311571 9 Q14168,Q8N3R9,O14936 3 +Guanylate kinase/L-type calcium channel beta subunit [IPR008145] 0.5831743069705506 1.2875728764799774 0.1978946860970023 1.0 0.2556788355311571 9 Q14168,Q8N3R9,O14936 3 +Far upstream element-binding protein, C-terminal [IPR015096] 0.6684976654765127 1.2823355071460112 0.199724977316912 1.0 0.2575309334562007 2 Q92945 1 +DALR anticodon binding [IPR008909] 0.6646525679758262 1.265173988611413 0.2058089646327749 1.0 0.2644356324227831 2 P54136 1 +Arginyl-tRNA synthetase, catalytic core domain [IPR035684] 0.6646525679758262 1.265173988611413 0.2058089646327749 1.0 0.2644356324227831 2 P54136 1 +Syntaxin, N-terminal domain [IPR006011] 0.742249765553509 1.2643978106489848 0.2060872783073373 1.0 0.2646714264186227 3 O15400 1 +Peptidase M41 [IPR000642] 0.6638286185113931 1.2614973734562842 0.2071297057026968 1.0 0.2657656885670632 2 Q9Y4W6 1 +Zinc finger, CHHC-type [IPR012996] 0.7329670329670338 1.2279239133521294 0.2194755316630301 1.0 0.2812187629202295 3 P55795,P31943 2 +TRASH domain [IPR011017] 0.678336652034513 1.223411089744869 0.2211744668530193 1.0 0.2828998768043163 5 Q5SVZ6,Q9UBW7 2 +Synaptic functional regulator FMRP, KH0 domain [IPR040472] 0.7280219780219789 1.2085073346151078 0.2268521762534294 1.0 0.2889467500454266 3 P51114,P51116 2 +Fxr1, tudor domain [IPR041560] 0.7280219780219789 1.2085073346151078 0.2268521762534294 1.0 0.2889467500454266 3 P51114,P51116 2 +Agenet-like domain [IPR008395] 0.7280219780219789 1.2085073346151078 0.2268521762534294 1.0 0.2889467500454266 3 P51114,P51116 2 +Fragile X-related 1 protein, C-terminal core [IPR022034] 0.7280219780219789 1.2085073346151078 0.2268521762534294 1.0 0.2889467500454266 3 P51114,P51116 2 +SAP domain [IPR003034] 0.5229216567850855 1.1880913849234271 0.2347974081149795 1.0 0.2979848599138482 13 P12956,Q9NWH9 2 +LEM domain [IPR003887] 0.634038443208601 1.1748192386504162 0.2400670415314691 1.0 0.3035630344002998 6 P42166,Q86XL3,Q9Y2U8 3 +STAT transcription factor, protein interaction [IPR013799] 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.3209128661687681 2 P42224 1 +STAT transcription factor, DNA-binding [IPR013801] 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.3209128661687681 2 P42224 1 +STAT transcription factor, all-alpha domain [IPR013800] 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.3209128661687681 2 P42224 1 +High mobility group box domain [IPR009071] 0.5129007299016555 1.13348188224586 0.2570119453892905 1.0 0.3225066748435501 13 O96028,P26583,P17480 3 +Cadherin-like [IPR002126] 0.6562149289367434 1.1327338708256405 0.2573260292961699 1.0 0.3227557384523388 5 P19022,Q9BQT9,O60245 3 +PTBP1, RNA recognition motif 2-like [IPR021790] 0.6347157374347652 1.1319138365187538 0.2576706609503119 1.0 0.3228978839197804 2 P26599 1 +NOPS [IPR012975] 0.7065934065934075 1.1245413020014452 0.260783459214263 1.0 0.3262130009526086 3 P23246,Q15233 2 +Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346] 0.6974785882050311 1.0889444311155485 0.2761783912883158 1.0 0.3439295577506591 3 Q93009 1 +Aldehyde dehydrogenase domain [IPR015590] 0.5170397436391612 1.0884392131829923 0.276401257934479 1.0 0.344053638944746 11 P30837 1 +Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615] 0.6972465097820897 1.0880392461428492 0.2765777822235724 1.0 0.3441199500749618 3 Q86UV5 1 +S1-like RNA binding domain [IPR025223] 0.623180444932705 1.0808388587707467 0.2797687997016291 1.0 0.3470077693322739 2 Q8IX12 1 +BURAN domain [IPR045354] 0.623180444932705 1.0808388587707467 0.2797687997016291 1.0 0.3470077693322739 2 Q8IX12 1 +LAIKA domain [IPR045353] 0.623180444932705 1.0808388587707467 0.2797687997016291 1.0 0.3470077693322739 2 Q8IX12 1 +DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954] 0.623180444932705 1.0808388587707467 0.2797687997016291 1.0 0.3470077693322739 2 Q8IX12 1 +CRAL-TRIO lipid binding domain [IPR001251] 0.6932771832252811 1.0725673900191417 0.2834652625874814 1.0 0.3514365067247993 3 Q07960 1 +PWWP domain [IPR000313] 0.5117197448647146 1.06082827698256 0.2887679490180126 1.0 0.3572175957723931 11 O96028 1 +Dynamin, GTPase domain [IPR001401] 0.6686697651520559 1.0591394736660211 0.2895362651006725 1.0 0.358009411940247 4 O60313,Q9UQ16 2 +Putative WW-binding domain and destruction box [IPR033461] 0.6168634990387195 1.052962899088815 0.292357996361027 1.0 0.3611785512566315 2 Q8TF05 1 +Serine/threonine-protein kinase N, C2 domain [IPR037784] 0.6146663004668984 1.043284721187825 0.2968164452443369 1.0 0.3658770486190679 2 Q16513 1 +Serine/threonine-protein kinase N, first HR1 domain [IPR037313] 0.6146663004668984 1.043284721187825 0.2968164452443369 1.0 0.3658770486190679 2 Q16513 1 +cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117] 0.6127437517165552 1.0348243790193694 0.3007509354673354 1.0 0.370563376798235 2 P13861 1 +SMCs flexible hinge [IPR010935] 0.632049966208721 1.034086030796029 0.3010959461649496 1.0 0.3708248265075162 5 O95347,Q9UQE7,Q9NTJ3 3 +Zinc finger, RING-CH-type [IPR011016] 0.6113705026091671 1.0287860466406518 0.3035802249798984 1.0 0.3730616144999456 2 Q9NX47 1 +ZU5 domain [IPR000906] 0.606976105465525 1.009491382496646 0.3127390323948171 1.0 0.383472717806908 2 Q07157 1 +PTB/PI domain [IPR006020] 0.6732005542600525 0.9946464355445246 0.3199082546086755 1.0 0.3915755575920308 3 O00213 1 +Immunoglobulin V-set domain [IPR013106] 0.6219001945577127 0.9928621793096032 0.3207771230876057 1.0 0.3924670147504799 5 Q9BY67 1 +Dynamin stalk domain [IPR000375] 0.6675241220797068 0.972735839726386 0.3306846078612757 1.0 0.4035277207817665 3 Q9UQ16 1 +Dynamin GTPase effector [IPR003130] 0.6675241220797068 0.972735839726386 0.3306846078612757 1.0 0.4035277207817665 3 Q9UQ16 1 +GTPase effector domain [IPR020850] 0.6675241220797068 0.972735839726386 0.3306846078612757 1.0 0.4035277207817665 3 Q9UQ16 1 +Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378] 0.5855206529338366 0.9692956548649212 0.3323976966275239 1.0 0.4054409650432707 6 Q9BT17,Q9NVN8 2 +Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001] 0.5970887118923307 0.966249581785944 0.3339193080937499 1.0 0.4067638342922119 2 A1L0T0 1 +Thiamine pyrophosphate enzyme, central domain [IPR012000] 0.5970887118923307 0.966249581785944 0.3339193080937499 1.0 0.4067638342922119 2 A1L0T0 1 +Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766] 0.5970887118923307 0.966249581785944 0.3339193080937499 1.0 0.4067638342922119 2 A1L0T0 1 +Gelsolin-like domain [IPR007123] 0.5813950576520032 0.9519632166729296 0.3411156369671269 1.0 0.4153488261719225 6 Q15437 1 +RasGAP protein, C-terminal [IPR000593] 0.6615868923671951 0.9498858356156592 0.3421702647542037 1.0 0.4164513422814895 3 Q86VI3 1 +Peptidase M28 [IPR007484] 0.65304711482066 0.9171529347548064 0.359062505706899 1.0 0.4341717262597063 3 P02786 1 +Suppressor of forked [IPR008847] 0.5847294699258374 0.912583970113987 0.3614613881652415 1.0 0.4363165567476672 2 Q14690 1 +NOSIC [IPR012976] 0.6492290356571275 0.9025737105544182 0.3667521844372983 1.0 0.4420566439780232 3 Q8WWY3 1 +Nop domain [IPR002687] 0.6492290356571275 0.9025737105544182 0.3667521844372983 1.0 0.4420566439780232 3 Q8WWY3 1 +Cyclic nucleotide-binding domain [IPR000595] 0.5974013388554889 0.8941240976351105 0.3712554973489921 1.0 0.4465942906498862 5 Q9Y4G8 1 +SANT domain [IPR017884] 0.5012640786233056 0.891574331721871 0.3726211333959364 1.0 0.4478511426781982 9 Q13330,Q96KC8,P28370 3 +TRAM domain [IPR002792] 0.5773139247459417 0.8806246688788618 0.3785210019820666 1.0 0.4541601364563515 2 Q96SZ6 1 +Methylthiotransferase, N-terminal [IPR013848] 0.5773139247459417 0.8806246688788618 0.3785210019820666 1.0 0.4541601364563515 2 Q96SZ6 1 +Target SNARE coiled-coil homology domain [IPR000727] 0.4810406362947056 0.8788849841886575 0.3794636410915581 1.0 0.4550955695565423 10 O60499,Q86Y82,Q8IZP0,O43752,O15400 5 +EF-hand domain [IPR002048] 0.342055035003346 0.8736466444742081 0.3823107159250203 1.0 0.458116531700711 50 Q9BRK5,Q02818,P12814,Q14257,Q9NZM3,O75071,O43707,Q8IYU8,Q9BPX6,Q13813,P80303 11 +Proteasome component (PCI) domain [IPR000717] 0.4053130400870819 0.8439839354397919 0.3986783825798778 1.0 0.4770785081986193 20 O00231,Q9H9Q2,Q9UNS2,P61201,Q9BT78 5 +K Homology domain, type 1 [IPR004088] 0.3991242817087065 0.8409247010510121 0.4003901194694508 1.0 0.4785484647083504 25 Q06787,Q07666,Q9UNW9,Q9NZI8,Q96PU8,P51114,Q9NQT5,Q13868,Q9Y6M1,P51116,Q92945,Q9Y2W6 12 +Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219] 0.505441537350528 0.8320858056315104 0.4053605132416917 1.0 0.4822183864383483 8 O75116,Q9Y5S2 2 +PDZ domain [IPR001478] 0.3849230646922254 0.8249019996906796 0.4094272309637532 1.0 0.4864343952556591 29 Q96L92,Q9Y4G8,Q14168,P57105,Q8N3R9,O14936 6 +Ras GTPase-activating domain [IPR001936] 0.6064461099318451 0.8172873984516673 0.4137642065150277 1.0 0.4905433819914894 4 Q86VI3 1 +Ubiquitin specific protease domain [IPR028889] 0.4120158559646393 0.8065957889817883 0.4198994006452503 1.0 0.4965519384165772 17 Q96K76,Q86UV5,Q8NB14,Q93009,Q9UPT9 5 +Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394] 0.4120158559646393 0.8065957889817883 0.4198994006452503 1.0 0.4965519384165772 17 Q96K76,Q86UV5,Q8NB14,Q93009,Q9UPT9 5 +DNA mismatch repair protein MutS, clamp [IPR007861] 0.5597363361713737 0.8057282713593688 0.4203995445430295 1.0 0.4969329078594997 2 P43246 1 +Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778] 0.6195054945054957 0.7904889131982881 0.4292422944695888 1.0 0.5063136823654804 3 Q9BUJ2,Q00839 2 +FAST kinase-like protein, subdomain 2 [IPR013579] 0.5539686899203436 0.7814543126237767 0.4345353377700975 1.0 0.5110457721373683 2 Q9NYY8 1 +FAST kinase leucine-rich [IPR010622] 0.5539686899203436 0.7814543126237767 0.4345353377700975 1.0 0.5110457721373683 2 Q9NYY8 1 +RAP domain [IPR013584] 0.5539686899203436 0.7814543126237767 0.4345353377700975 1.0 0.5110457721373683 2 Q9NYY8 1 +SH3 domain [IPR001452] 0.3494505731624596 0.7682575503705116 0.4423341886991898 1.0 0.5195612346857964 41 Q9Y5X1,Q96RU3,Q14168,Q8N3R9,Q9UQB8,Q13813,Q14185 7 +Calponin homology domain [IPR001715] 0.3730290783376666 0.762349697327243 0.4458513201079084 1.0 0.5234721975362827 30 P12814,Q15555,Q86VI3,O43707,Q5M775,Q96ED9,P46939 7 +Zinc finger, PHD-type [IPR001965] 0.3897364371472585 0.7589627473614114 0.4478748415927716 1.0 0.5252337862278249 23 Q8IWS0,Q9BZ95,Q9UIF9,Q96L73,Q9NRL2,O96028,Q8WUB8,Q9Y2K7,Q14839,Q9UIG0 10 +Phox homology [IPR001683] 0.4320732567926289 0.7459941160123988 0.4556709694422962 1.0 0.5327610329492845 14 Q9Y5X1,Q53T59,Q96L92,O95219,Q9Y5X2 5 +PIK-related kinase, FAT [IPR003151] 0.6049450549450562 0.7366936499900884 0.4613086693042232 1.0 0.5389011735135528 3 Q9Y4A5,P42345 2 +Peptidase C2, calpain, domain III [IPR022683] 0.5919576312332964 0.6894691235228179 0.4905280972263874 1.0 0.5689881377050576 3 O15484 1 +Peptidase C2, calpain, large subunit, domain III [IPR022682] 0.5919576312332964 0.6894691235228179 0.4905280972263874 1.0 0.5689881377050576 3 O15484 1 +Calpain subdomain III [IPR033883] 0.5919576312332964 0.6894691235228179 0.4905280972263874 1.0 0.5689881377050576 3 O15484 1 +Peptidase C2, calpain, catalytic domain [IPR001300] 0.5919576312332964 0.6894691235228179 0.4905280972263874 1.0 0.5689881377050576 3 O15484 1 +MHC class I-like antigen recognition-like [IPR011161] 0.5384784379131797 0.6640198687616927 0.5066775945552513 1.0 0.5838398035486015 5 P30511,P10321 2 +Exportin-2, central domain [IPR013713] 0.583951478297163 0.6607595897943259 0.508766501814097 1.0 0.5860049806373592 3 O15397 1 +ERM family, FERM domain C-lobe [IPR041789] 0.5823565411671765 0.6550796698300458 0.512416460713812 1.0 0.5894795048673107 3 P26038 1 +Zinc finger, PHD-finger [IPR019787] 0.3748695263413385 0.6547440818272221 0.5126325384186559 1.0 0.5894851924484708 22 Q9BZ95,Q9UIF9,Q96L73,Q9NRL2,O96028,Q8WUB8,Q9Y2K7,Q14839,Q9UIG0 9 +Post-SET domain [IPR003616] 0.5355575586146082 0.6530027797549912 0.5137544864566008 1.0 0.5905321227611484 5 O96028,Q96L73 2 +Sterile alpha motif domain [IPR001660] 0.4758484935513908 0.6383682095555032 0.52323402005628 1.0 0.6006864243409267 7 Q13136 1 +Ribosomal protein L26/L24, KOW domain [IPR041988] 0.5166163141993885 0.6288673815387849 0.5294358822159719 1.0 0.6063104934975364 2 Q96A35 1 +K Homology domain [IPR004087] 0.3683955151557255 0.6240511860049494 0.5325939701210172 1.0 0.6081442699030702 24 Q06787,Q07666,Q9UNW9,Q9NZI8,Q96PU8,P51114,Q9Y6M1,P51116,Q92945,Q9Y2W6,Q13601 11 +rRNA-processing arch domain [IPR025696] 0.515243065091999 0.6234368280833855 0.5329975030275118 1.0 0.6081442699030702 2 Q15477 1 +ATP-dependent RNA helicase Ski2, C-terminal [IPR012961] 0.515243065091999 0.6234368280833855 0.5329975030275118 1.0 0.6081442699030702 2 Q15477 1 +SMARCC, N-terminal [IPR032450] 0.5124965668772226 0.61261953597337 0.5401279376693986 1.0 0.6155253885603922 2 Q8TAQ2 1 +SMARCC, C-terminal [IPR032451] 0.5124965668772226 0.61261953597337 0.5401279376693986 1.0 0.6155253885603922 2 Q8TAQ2 1 +SMARCC, SWIRM-associated domain [IPR032448] 0.5124965668772226 0.61261953597337 0.5401279376693986 1.0 0.6155253885603922 2 Q8TAQ2 1 +Bms1/Tsr1-type G domain [IPR030387] 0.511397967591312 0.6083092571305772 0.5429823825047484 1.0 0.6173215369229421 2 Q14692 1 +AARP2CN [IPR012948] 0.511397967591312 0.6083092571305772 0.5429823825047484 1.0 0.6173215369229421 2 Q14692 1 +Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034] 0.511397967591312 0.6083092571305772 0.5429823825047484 1.0 0.6173215369229421 2 Q14692 1 +Guanylate-binding protein/Atlastin, C-terminal [IPR003191] 0.5108486679483568 0.606157733921665 0.544410016217171 1.0 0.6181345121099396 2 Q8NHH9 1 +GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386] 0.5108486679483568 0.606157733921665 0.544410016217171 1.0 0.6181345121099396 2 Q8NHH9 1 +Guanylate-binding protein, N-terminal [IPR015894] 0.5108486679483568 0.606157733921665 0.544410016217171 1.0 0.6181345121099396 2 Q8NHH9 1 +Myb domain [IPR017930] 0.4632062861827224 0.5866442519650126 0.5574426559817349 1.0 0.6301133180166008 7 Q13330,Q96KC8 2 +Core histone macro-H2A, macro domain [IPR035796] 0.5050810216973282 0.583715788320123 0.5594115431946833 1.0 0.6316049311305988 2 O75367 1 +Major sperm protein (MSP) domain [IPR000535] 0.561948609577662 0.5836721608030339 0.559440900675491 1.0 0.6316049311305988 3 Q8NHP6 1 +Histone deacetylase domain [IPR023801] 0.5020598736610726 0.5720723475786397 0.5672729620269941 1.0 0.63889718030632 2 Q92769 1 +p21 activated kinase binding domain [IPR033923] 0.5001373249107317 0.5647042724088714 0.5722749277598385 1.0 0.6427158480713874 2 Q13177 1 +Dbl homology (DH) domain [IPR000219] 0.4568058618832359 0.5608905666987682 0.5748721411813631 1.0 0.6445955896298657 7 P11274,Q9NZM3 2 +Zinc finger, PARP-type [IPR001510] 0.4982147761603859 0.5573690652490848 0.5772752966767001 1.0 0.6470303606267951 2 P49916 1 +Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038] 0.4907992309804909 0.5293945452609559 0.5965317813531499 1.0 0.6656741540919242 2 P29692 1 +Elongation factor 1 beta central acidic region, eukaryote [IPR018940] 0.4907992309804909 0.5293945452609559 0.5965317813531499 1.0 0.6656741540919242 2 P29692 1 +Alcohol dehydrogenase-like, C-terminal [IPR013149] 0.4299572824739737 0.505632416153284 0.6131147207513028 1.0 0.6809275991905943 8 Q8N8N7 1 +MCM N-terminal domain [IPR027925] 0.4693010950786808 0.504919649999497 0.6136152720499768 1.0 0.6809275991905943 6 Q14566 1 +MCM, AAA-lid domain [IPR041562] 0.4693010950786808 0.504919649999497 0.6136152720499768 1.0 0.6809275991905943 6 Q14566 1 +MCM OB domain [IPR033762] 0.4693010950786808 0.504919649999497 0.6136152720499768 1.0 0.6809275991905943 6 Q14566 1 +MCM domain [IPR001208] 0.4693010950786808 0.504919649999497 0.6136152720499768 1.0 0.6809275991905943 6 Q14566 1 +Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120] 0.4710244438341013 0.4574840503605105 0.6473231638109409 1.0 0.714075967348932 2 Q9Y305 1 +Rpn11/EIF3F, C-terminal [IPR024969] 0.502961767897189 0.4492190836055915 0.6532736222985478 1.0 0.7189357325414054 4 O00303,O00487 2 +Helicase/SANT-associated domain [IPR014012] 0.4592145015105636 0.4166064474384658 0.6769662926332378 1.0 0.7432520208541092 2 P51532 1 +Kinesin motor domain [IPR001752] 0.3708281256965587 0.3953577795069776 0.6925788633516896 1.0 0.7586034470293909 13 Q9Y496,Q02241,P52732,Q14807,O95239,P33176 6 +Translation elongation factor EFTu-like, domain 2 [IPR004161] 0.3762730525736298 0.3874890269574735 0.698394206907885 1.0 0.7641741213507067 10 Q05639,Q8N442,Q15029,P41091,P49411,O60841,P13639,Q9Y450,Q96RP9 9 +Serine hydroxymethyltransferase-like domain [IPR039429] 0.4498764075803242 0.3854939649025412 0.6998714769571315 1.0 0.7653901933663577 2 P34897 1 +Ribosomal protein L30, ferredoxin-like fold domain [IPR016082] 0.448777808294416 0.3819074523331101 0.702530012370373 1.0 0.7673958507582479 2 Q6DKI1 1 +Ribosomal protein L30, N-terminal [IPR012988] 0.448777808294416 0.3819074523331101 0.702530012370373 1.0 0.7673958507582479 2 Q6DKI1 1 +Ribosomal protein L7, eukaryotic/archaeal [IPR035808] 0.448777808294416 0.3819074523331101 0.702530012370373 1.0 0.7673958507582479 2 Q6DKI1 1 +Peptidase M16, C-terminal [IPR007863] 0.4079586779670796 0.3765602340441724 0.7065004445618184 1.0 0.7705292139612179 7 P22695,Q10713,Q5JRX3 3 +Peptidase M16, N-terminal [IPR011765] 0.4079586779670796 0.3765602340441724 0.7065004445618184 1.0 0.7705292139612179 7 P22695,Q10713,Q5JRX3 3 +Pseudouridine synthase II, N-terminal [IPR002501] 0.4471299093655517 0.376557561307505 0.7065024311392256 1.0 0.7705292139612179 2 Q8WWH5 1 +Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547] 0.4457566602581646 0.372126940030902 0.7097983391456058 1.0 0.773687679515692 2 P13674 1 +SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678] 0.4734817257488513 0.3587186287547532 0.7198055909459551 1.0 0.783660182287326 4 Q96P11,Q96CB9,Q08J23 3 +SANT/Myb domain [IPR001005] 0.3601034311848792 0.3360357620529152 0.7368438987149313 1.0 0.7992494814343777 12 Q99543,P28370,Q15910,Q13330,O60264,Q96KC8 6 +Matrin/U1-C, C2H2-type zinc finger [IPR000690] 0.4154095646596254 0.3220634097911821 0.7474046573620836 1.0 0.8103898265456068 6 Q9ULV3,Q14966,P43243,Q12874 4 +Ribosomal protein S5, C-terminal [IPR005324] 0.4246086240043892 0.3072188875120454 0.7586767700938803 1.0 0.8196658011807664 2 P82675 1 +Ribosomal protein S5, N-terminal [IPR013810] 0.4246086240043892 0.3072188875120454 0.7586767700938803 1.0 0.8196658011807664 2 P82675 1 +APC10/DOC domain [IPR004939] 0.4718421814720451 0.3069315816324407 0.7588954498754588 1.0 0.8196658011807664 3 O75592 1 +IKBKB, scaffold dimerization domain [IPR041185] 0.4218621257896104 0.2992683328564875 0.7647353146950711 1.0 0.8231445693877376 2 O15111 1 +I-kappa-kinase-beta NEMO binding domain [IPR022007] 0.4218621257896104 0.2992683328564875 0.7647353146950711 1.0 0.8231445693877376 2 O15111 1 +Dynein heavy chain, AAA module D4 [IPR024317] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8231445693877376 2 Q8NCM8 1 +Dynein heavy chain, tail [IPR013594] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8231445693877376 2 Q8NCM8 1 +Dynein heavy chain AAA lid domain [IPR041658] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8231445693877376 2 Q8NCM8 1 +Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8231445693877376 2 Q8NCM8 1 +Dynein heavy chain, linker [IPR013602] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8231445693877376 2 Q8NCM8 1 +Dynein heavy chain, C-terminal domain [IPR041228] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8231445693877376 2 Q8NCM8 1 +Dynein heavy chain, ATP-binding dynein motor region [IPR035706] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8231445693877376 2 Q8NCM8 1 +Dynein heavy chain, coiled coil stalk [IPR024743] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8231445693877376 2 Q8NCM8 1 +Dynein heavy chain region D6 P-loop domain [IPR004273] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8231445693877376 2 Q8NCM8 1 +CAP Gly-rich domain [IPR000938] 0.4654609843894143 0.2904102471418421 0.7715024052613431 1.0 0.8272022716934215 3 Q14203 1 +SNF2, N-terminal [IPR000330] 0.3329447667380133 0.2794571071676878 0.7798940507395886 1.0 0.834917250638394 15 Q9UNY4,P28370,Q14527,P51532,Q9H4L7,Q9NRZ9,Q2NKX8,O14646,Q14839 9 +Ribosomal L28e/Mak16 [IPR029004] 0.4095028838231191 0.264933492894738 0.791060696346328 1.0 0.846260783417869 2 P46779 1 +Beta-Casp domain [IPR022712] 0.4390799056723989 0.2648873813393044 0.791096219455816 1.0 0.846260783417869 4 Q9NV88,Q9UKF6 2 +G-patch domain [IPR000467] 0.3257610929435424 0.2475330759971925 0.8044956968240198 1.0 0.858292696038465 15 P52756,P98175 2 +Class I myosin, motor domain [IPR036072] 0.4469616559007491 0.2452940688679595 0.8062287438544835 1.0 0.8591567377258466 3 O94832 1 +Class I myosin tail homology domain [IPR010926] 0.4469616559007491 0.2452940688679595 0.8062287438544835 1.0 0.8591567377258466 3 O94832 1 +DNA/RNA non-specific endonuclease [IPR001604] 0.4009887393573154 0.2426973461696238 0.8082398634501555 1.0 0.8595975486132499 2 Q14249 1 +Extracellular Endonuclease, subunit A [IPR020821] 0.4009887393573154 0.2426973461696238 0.8082398634501555 1.0 0.8595975486132499 2 Q14249 1 +WHIM2 domain [IPR028941] 0.4259951778669663 0.2329889590677308 0.8157699792585302 1.0 0.8653608594566172 4 Q9UIF9,Q9UIG0 2 +DDT domain [IPR018501] 0.4259951778669663 0.2329889590677308 0.8157699792585302 1.0 0.8653608594566172 4 Q9UIF9,Q9UIG0 2 +BAT2, N-terminal [IPR009738] 0.3946717934633268 0.2269697247362094 0.8204472839925505 1.0 0.8696616616959761 2 Q9Y520 1 +Helicase/UvrB, N-terminal [IPR006935] 0.4362637362637381 0.221170959354178 0.8249593204183836 1.0 0.8727875796165696 3 Q9UPY3,P19447 2 +Sorting nexin Vps5-like, C-terminal [IPR015404] 0.4160762635978135 0.210307005563978 0.8334280679073511 1.0 0.8807460884168524 4 O60749 1 +Brix domain [IPR007109] 0.3930731170973124 0.2034318383889557 0.838797516621234 1.0 0.8860850043157342 5 Q9H7B2,Q96G21,Q9H9Y2,Q9NQ55 4 +Acyl transferase [IPR014043] 0.3707772589947781 0.1735994149706064 0.8621802918254529 1.0 0.9046250938657138 2 Q8IVS2 1 +GAR domain [IPR003108] 0.369678659708864 0.1713822620664267 0.8639232012521407 1.0 0.906113289968436 2 Q9UPN3 1 +Chromo/chromo shadow domain [IPR000953] 0.311037709881644 0.1508888150486268 0.8800634237637295 1.0 0.919243202075695 10 P45973,P83916,Q9P2D1,Q92922,Q9HC52,Q8TAQ2,Q13185,O14646,Q14839 9 +Spt5 C-terminal domain [IPR024945] 0.3551222191705521 0.1439834847512772 0.8855135109978947 1.0 0.9242443823200494 2 O00267 1 +mRNA splicing factor Cwf21 domain [IPR013170] 0.3551222191705495 0.1439834847512727 0.8855135109978982 1.0 0.9242443823200494 2 O15042 1 +Sec63 domain [IPR004179] 0.3934065934065953 0.1398160544939128 0.8888053282435535 1.0 0.9269871036443784 3 O75643,Q9UGP8 2 +ARID DNA-binding domain [IPR001606] 0.3912087912087929 0.1363169687292378 0.8915707099931478 1.0 0.928889763063638 3 Q68CP9,O14497 2 +Translation elongation factor EFTu/EF1A, C-terminal [IPR004160] 0.3756526518274474 0.1319249472945585 0.8950436559995505 1.0 0.9317531273492712 4 Q05639,Q9Y450,P49411 3 +Small-subunit processome, Utp12 [IPR007148] 0.3865384615384634 0.1290994595674947 0.8972789496333302 1.0 0.9337319520597308 3 Q15269,Q15061 2 +RNA recognition motif domain, eukaryote [IPR003954] 0.294038824099189 0.1214288320012636 0.9033513812096334 1.0 0.9386516770886848 15 Q9UHX1 1 +Chromo domain [IPR023780] 0.3108665749656232 0.1190284386101621 0.9052528251863126 1.0 0.9399278125400464 8 P45973,P83916,Q9P2D1,Q9HC52,Q13185,O14646,Q14839 7 +Rho GTPase-activating protein domain [IPR000198] 0.3087434726157373 0.1143626812838763 0.9089502958782028 1.0 0.9405417765173052 8 P11274,Q07960 2 +RNA polymerase Rpb1, domain 4 [IPR007083] 0.376098901098903 0.1140314759415882 0.9092128419843148 1.0 0.9405417765173052 3 O14802,O95602 2 +RNA polymerase Rpb1, domain 5 [IPR007081] 0.376098901098903 0.1140314759415882 0.9092128419843148 1.0 0.9405417765173052 3 O14802,O95602 2 +RNA polymerase, alpha subunit [IPR000722] 0.376098901098903 0.1140314759415882 0.9092128419843148 1.0 0.9405417765173052 3 O14802,O95602 2 +RNA polymerase Rpb1, domain 3 [IPR007066] 0.376098901098903 0.1140314759415882 0.9092128419843148 1.0 0.9405417765173052 3 O14802,O95602 2 +RNA polymerase Rpb1, domain 1 [IPR007080] 0.376098901098903 0.1140314759415882 0.9092128419843148 1.0 0.9405417765173052 3 O14802,O95602 2 +RNA polymerase, N-terminal [IPR006592] 0.376098901098903 0.1140314759415882 0.9092128419843148 1.0 0.9405417765173052 3 O14802,O95602 2 +Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058] 0.3747252747252768 0.1121575211995921 0.910698509762035 1.0 0.9417297182428156 3 P07814,Q5JPH6 2 +EH domain [IPR000261] 0.3295924131514641 0.1109477904768183 0.91165774818507 1.0 0.9423726149325122 6 Q9H223,Q9NZM3 2 +Formin, FH2 domain [IPR015425] 0.3569661995053683 0.103483168760051 0.9175795071563057 1.0 0.947441562122931 4 O60610,Q9NSV4,Q9Y613 3 +Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768] 0.3569661995053683 0.103483168760051 0.9175795071563057 1.0 0.947441562122931 4 O60610,Q9NSV4,Q9Y613 3 +Beta-adaptin appendage, C-terminal subdomain [IPR015151] 0.3675824175824194 0.1028152127349638 0.918109631236038 1.0 0.9476384807434448 3 O00203,Q10567 2 +Histidine kinase/HSP90-like ATPase [IPR003594] 0.2974683544303731 0.099007887614992 0.9211320074667608 1.0 0.9502068789921873 9 Q12931,Q15120,P11388,P08238,Q15118,P14625,P07900,O14874 8 +DnaJ domain [IPR001623] 0.2745688978820756 0.098480567389602 0.921550701920672 1.0 0.9502068789921873 20 Q99615,Q99543,O14976,Q96KC8,Q9NXW2,O60884,Q13217,Q8IXB1,Q9UGP8,O75165 10 +SCP2 sterol-binding domain [IPR003033] 0.3640109890109911 0.098394561591256 0.9216189929480096 1.0 0.9502068789921873 3 P22307,Q6YN16 2 +Formin, FH3 domain [IPR010472] 0.3568681318681337 0.0900456406024793 0.9282509461583656 1.0 0.9556329799683468 3 O60610,Q9NSV4 2 +Formin, GTPase-binding domain [IPR010473] 0.3568681318681337 0.0900456406024793 0.9282509461583656 1.0 0.9556329799683468 3 O60610,Q9NSV4 2 +OBG-type guanine nucleotide-binding (G) domain [IPR031167] 0.3317757009345834 0.0894790381789778 0.928701211861514 1.0 0.9557441148239394 5 A4D1E9,Q9BZE4,P55039,Q9NTK5 4 +KOW [IPR005824] 0.3117954357987488 0.0820224017556417 0.9346288994501152 1.0 0.960428372199014 6 P61254,P61353,P62701,O00267,Q96A35 5 +3'-5' exonuclease domain [IPR002562] 0.3439560439560458 0.0765727710496048 0.9389634208920228 1.0 0.9623416491860072 3 Q01780,Q9NVH0 2 +Chromo shadow domain [IPR008251] 0.3431318681318701 0.075781562071961 0.9395928852725844 1.0 0.9623416491860072 3 Q13185,P45973 2 +Chromo domain subgroup [IPR017984] 0.3431318681318701 0.075781562071961 0.9395928852725844 1.0 0.9623416491860072 3 Q13185,P45973 2 +Ataxin-2, C-terminal [IPR009818] 0.3390109890109912 0.071945796418084 0.9426450441838576 1.0 0.9644063625362148 3 Q14694,Q9BPZ3 2 +Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141] 0.2952485580884315 0.0682085605106734 0.9456196125420346 1.0 0.9667411051693008 2 P20020 1 +E3 ligase, CCCH-type zinc finger [IPR041367] 0.3324175824175845 0.0662169931062368 0.9472050679239798 1.0 0.9680075218315344 3 Q86VM9,Q9UPT8 2 +Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108] 0.3272080942841496 0.0620352992068302 0.9505347214221552 1.0 0.9704067046281424 3 Q9UKF6 1 +Translational (tr)-type GTP-binding domain [IPR000795] 0.2812672176308589 0.061959112427384 0.9505953929648888 1.0 0.9704067046281424 13 Q05639,Q8N442,P46199,P15170,Q15029,P41091,P49411,O60841,Q7Z2Z2,P13639,Q9Y450,Q96RP9 12 +Metallo-beta-lactamase [IPR001279] 0.3076764789500898 0.0600854318415906 0.9520875927050364 1.0 0.9712197876625728 5 Q9NV88,Q9UKF6 2 +FF domain [IPR002713] 0.3174075596611372 0.0549553157490842 0.956174062827791 1.0 0.974676153127124 3 O14776 1 +BRK domain [IPR006576] 0.3104395604395625 0.0505142686837595 0.9597125791556352 1.0 0.9768565515867784 3 P51532,Q9P2D1 2 +Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245] 0.2720022002200297 0.045623234064447 0.9636105503459496 1.0 0.9797526061784018 7 Q13418,Q13308,O43318,Q15375,Q9UHY1,P41240 6 +Cullin homology domain [IPR016158] 0.277426450371198 0.0404634021911382 0.9677236839527052 1.0 0.9822926294671944 6 Q93034,Q13618,Q9UJX6,Q13620,Q13617 5 +Cullin, N-terminal [IPR001373] 0.277426450371198 0.0404634021911382 0.9677236839527052 1.0 0.9822926294671944 6 Q93034,Q13618,Q9UJX6,Q13620,Q13617 5 +PWI domain [IPR002483] 0.2827897113944084 0.037984275974302 0.9697002189356908 1.0 0.9827234160684024 5 O43395 1 +C2 domain [IPR000008] 0.2578697564554428 0.0283814777529533 0.9773578968625388 1.0 0.9890479333237436 22 P11274,O15484,Q96PE3,Q9NZM3 4 +Band 7 domain [IPR001107] 0.2537351235337979 0.0244515690297453 0.9804924144664908 1.0 0.9913887418469496 8 O75955 1 +GTP binding domain [IPR006073] 0.2645515281072121 0.0241458336267535 0.9807362840190812 1.0 0.9913887418469496 14 Q9NVN8,Q9BZE4 2 +Zinc finger, CCHC-type [IPR001878] 0.2507098425021906 0.0159506777214407 0.9872737401585848 1.0 0.9965539705433004 9 Q5TAX3,Q6ZN17 2 +FERM, C-terminal PH-like domain [IPR018980] 0.2382346390495874 0.0130876521317186 0.9895578625275648 1.0 0.997777375289621 7 P15311,O43491,P26038 3 +FERM, N-terminal [IPR018979] 0.2382346390495874 0.0130876521317186 0.9895578625275648 1.0 0.997777375289621 7 P15311,O43491,P26038 3 +FERM central domain [IPR019748] 0.2393545948648566 0.0025749837598167 0.9979454624841736 1.0 1.0 9 Q96AC1,P15311,O43491,P26038 4 +Band 4.1 domain [IPR019749] 0.2393545948648566 0.0025749837598167 0.9979454624841736 1.0 1.0 9 Q96AC1,P15311,O43491,P26038 4 diff --git a/interpro_domain/selections.json b/interpro_domain/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..c16ff61484b615cc37602cfc96cb16bb5d49623c --- /dev/null +++ b/interpro_domain/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1-acyl-sn-glycerol-3-phosphate acyltransferase [IPR004552]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1, SH3 domain [IPR035724]", "116kDa U5 small nuclear ribonucleoprotein component, C-terminal [IPR035655]", "116kDa U5 small nuclear ribonucleoprotein component, N-terminal [IPR031950]", "14-3-3 domain [IPR023410]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23, C-terminal [IPR022238]", "2-oxoacid dehydrogenase acyltransferase, catalytic domain [IPR001078]", "2-oxoglutarate dehydrogenase E1 component, N-terminal domain [IPR032106]", "26S proteasome non-ATPase regulatory subunit RPN1, C-terminal [IPR041433]", "26S proteasome regulatory subunit RPN2, C-terminal [IPR040623]", "26S proteasome regulatory subunit RPN5, C-terminal domain [IPR040896]", "26S proteasome regulatory subunit Rpn6, N-terminal [IPR040773]", "26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]", "26S proteasome regulatory subunit, C-terminal [IPR013586]", "2Fe-2S ferredoxin-type iron-sulfur binding domain [IPR001041]", "3'-5' exonuclease domain [IPR002562]", "3-beta hydroxysteroid dehydrogenase/isomerase [IPR002225]", "3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]", "3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]", "3-hydroxyisobutyrate dehydrogenase, NAD-binding domain [IPR029154]", "3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal [IPR001104]", "3-oxoacid CoA-transferase, subunit A [IPR012792]", "3-oxoacid CoA-transferase, subunit B [IPR012791]", "4'-phosphopantetheinyl transferase domain [IPR008278]", "40S ribosomal protein S11, N-terminal [IPR032440]", "40S ribosomal protein S4, C-terminal domain [IPR032277]", "40S ribosomal protein SA, C-terminal domain [IPR032281]", "4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]", "5'-AMP-activated protein kinase catalytic subunit alpha-2, C-terminal [IPR039148]", "6-phosphogluconate dehydrogenase, C-terminal [IPR006114]", "6-phosphogluconate dehydrogenase, NADP-binding [IPR006115]", "6-phosphogluconolactonase, DevB-type [IPR005900]", "60S ribosomal protein L10P, insertion domain [IPR040637]", "60S ribosomal protein L4, C-terminal domain [IPR025755]", "6S proteasome subunit Rpn6, C-terminal helix domain [IPR040780]", "A kinase-anchoring protein AKAP5 and AKAP12, calmodulin (CaM)-binding motif [IPR001573]", "AAA ATPase, AAA+ lid domain [IPR041569]", "AAA+ ATPase domain [IPR003593]", "AARP2CN [IPR012948]", "AATF leucine zipper-containing domain [IPR025160]", "ABC transporter type 1, transmembrane domain [IPR011527]", "ABC transporter-like, ATP-binding domain [IPR003439]", "ABC-transporter extension domain [IPR032781]", "ABC-type uncharacterised transport system [IPR019196]", "ABC1 atypical kinase-like domain [IPR004147]", "ABT1/ESF2, RNA recognition motif [IPR034353]", "ADAM10/ADAM17 catalytic domain [IPR034025]", "ADAM17, membrane-proximal domain [IPR032029]", "ADAR1, first double-stranded RNA binding domain [IPR044456]", "ADAR1, third double-stranded RNA binding domain [IPR044457]", "ADCK3-like domain [IPR034646]", "ADD domain [IPR025766]", "ADNP, zinc finger domain [IPR045762]", "AGC-kinase, C-terminal [IPR000961]", "AIMP2, lysyl-tRNA synthetase binding domain [IPR031889]", "AIMP2, thioredoxin-like domain [IPR041503]", "ALIX V-shaped domain [IPR025304]", "AMP-binding enzyme, C-terminal domain [IPR025110]", "AMP-dependent synthetase/ligase [IPR000873]", "AMPK, C-terminal adenylate sensor domain [IPR032270]", "AP complex, mu/sigma subunit [IPR022775]", "AP-2 complex subunit mu, N-terminal [IPR043532]", "AP-3 complex subunit beta 1, serine-rich domain [IPR029394]", "AP-3 complex subunit beta, C-terminal domain [IPR029390]", "AP-3 complex subunit delta domain, metazoa [IPR010474]", "AP180 N-terminal homology (ANTH) domain [IPR011417]", "APC10/DOC domain [IPR004939]", "ARHGEF1-like, PH domain [IPR041020]", "ARHGEF2, PH domain [IPR037806]", "ARID DNA-binding domain [IPR001606]", "ARMET, C-terminal [IPR019345]", "ARMET, N-terminal [IPR045332]", "ASCH domain [IPR007374]", "ATP synthase, F1 complex, alpha subunit nucleotide-binding domain [IPR033732]", "ATP synthase, alpha subunit, C-terminal [IPR000793]", "ATP-citrate lyase/succinyl-CoA ligase [IPR005811]", "ATP-citrate synthase, citrate-binding domain [IPR032263]", "ATP-cone domain [IPR005144]", "ATP-dependent DNA helicase RecQ, zinc-binding domain [IPR032284]", "ATP-dependent RNA helicase Ski2, C-terminal [IPR012961]", "ATP-dependent RNA helicase eIF4A, DEAD-box helicase domain [IPR044728]", "ATP-dependent helicase, C-terminal [IPR006555]", "ATP-grasp fold [IPR011761]", "ATP-grasp fold, succinyl-CoA synthetase-type [IPR013650]", "ATP-sulfurylase PUA-like domain [IPR025980]", "ATP:guanido phosphotransferase, N-terminal [IPR022413]", "ATP:guanido phosphotransferase, catalytic domain [IPR022414]", "ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]", "ATPase, AAA-type, core [IPR003959]", "ATPase, BadF/BadG/BcrA/BcrD type [IPR002731]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain [IPR004100]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, nucleotide-binding domain [IPR000194]", "ATPase, V1 complex, subunit H, C-terminal [IPR011987]", "ATPase, dynein-related, AAA domain [IPR011704]", "ATPsynthase alpha/beta subunit, N-terminal extension [IPR031686]", "ATRX, ADD domain [IPR041430]", "AWS domain [IPR006560]", "Abl Interactor 1, SH3 domain [IPR035725]", "Abl-interactor, homeo-domain homologous domain [IPR012849]", "Abscisic acid G-protein coupled receptor-like domain [IPR025969]", "Acetyl-CoA carboxylase [IPR034733]", "Acetyl-CoA carboxylase, central domain [IPR013537]", "Acetyl-coA carboxylase zinc finger domain [IPR041010]", "Acetyl-coenzyme A carboxyltransferase, C-terminal [IPR011763]", "Acetyl-coenzyme A carboxyltransferase, N-terminal [IPR011762]", "Acid ceramidase, N-terminal [IPR029130]", "Acinus, RNA recognition motif [IPR034257]", "Aconitase A, swivel domain [IPR044137]", "Aconitase A/isopropylmalate dehydratase small subunit, swivel domain [IPR000573]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha domain [IPR001030]", "Actin-depolymerising factor homology domain [IPR002108]", "Activating signal cointegrator 1 complex subunit 2, CUE domain [IPR041800]", "Activator of Hsp90 ATPase, N-terminal [IPR015310]", "Active breakpoint cluster region-related protein, PH domain [IPR037865]", "Acyl transferase [IPR014043]", "Acyl-CoA dehydrogenase family member 10/11, N-terminal [IPR041726]", "Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]", "Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]", "Acyl-CoA oxidase, C-terminal [IPR002655]", "Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]", "Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase [IPR006862]", "Acyl-CoA-binding protein, ACBP [IPR000582]", "Acyl-coenzyme A oxidase, N-terminal [IPR029320]", "Acylamino-acid-releasing enzyme, N-terminal domain [IPR045550]", "Acylglycerol kinase, C-terminal [IPR045579]", "Acyltransferase, C-terminal domain [IPR032098]", "Adenosine deaminase domain [IPR001365]", "Adenosine deaminase/editase [IPR002466]", "Adenylate cyclase-associated CAP, C-terminal [IPR013912]", "Adenylate cyclase-associated CAP, N-terminal [IPR013992]", "Adenylate kinase, active site lid domain [IPR007862]", "Adenylosuccinate lyase C-terminal [IPR019468]", "Afadin, cargo binding domain [IPR037977]", "Agenet-like domain [IPR008395]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal [IPR007886]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain [IPR007698]", "Alanine racemase, N-terminal [IPR001608]", "Alanyl-tRNA synthetase, class IIc, N-terminal [IPR018164]", "Alanyl-tRNA synthetase, class IIc, core domain [IPR018165]", "Alcohol dehydrogenase, N-terminal [IPR013154]", "Alcohol dehydrogenase-like, C-terminal [IPR013149]", "Aldehyde dehydrogenase domain [IPR015590]", "Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidant [IPR000866]", "Alpha Spectrin, SH3 domain [IPR035825]", "Alpha galactosidase A, C-terminal beta-sandwich domain [IPR035373]", "Alpha-2-macroglobulin RAP, C-terminal [IPR010483]", "Alpha-2-macroglobulin RAP, domain 2 [IPR038001]", "Alpha-2-macroglobulin RAP, domain 3 [IPR037999]", "Alpha-2-macroglobulin [IPR001599]", "Alpha-2-macroglobulin receptor-associated protein, domain 1 [IPR009066]", "Alpha-2-macroglobulin, TED domain [IPR041813]", "Alpha-2-macroglobulin, bait region domain [IPR011625]", "Alpha-D-phosphohexomutase, C-terminal [IPR005843]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain I [IPR005844]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain II [IPR005845]", "Alpha-D-phosphohexomutase, alpha/beta/alpha domain III [IPR005846]", "Alpha-L-fucosidase, C-terminal [IPR031919]", "Alpha-N-acetylglucosaminidase, C-terminal [IPR024732]", "Alpha-N-acetylglucosaminidase, N-terminal [IPR024240]", "Alpha-N-acetylglucosaminidase, tim-barrel domain [IPR024733]", "Alpha-glycerophosphate oxidase, C-terminal [IPR031656]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like [IPR027450]", "Alpha-ketoglutarate-dependent dioxygenase FTO, C-terminal [IPR024366]", "Alpha-ketoglutarate-dependent dioxygenase FTO, catalytic domain [IPR024367]", "Alpha-macroglobulin, receptor-binding [IPR009048]", "Alpha-macroglobulin-like, TED domain [IPR011626]", "Alpha/beta hydrolase fold-1 [IPR000073]", "Alpha/beta hydrolase fold-3 [IPR013094]", "Amidase signature domain [IPR023631]", "Amidohydrolase-related [IPR006680]", "Amidophosphoribosyltransferase, N-terminal [IPR035584]", "Amine oxidase [IPR002937]", "Amino acid permease, N-terminal [IPR013612]", "Amino acid permease/ SLC12A domain [IPR004841]", "Amino acid transporter, transmembrane domain [IPR013057]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding [IPR045462]", "Aminoacyl-tRNA synthetase, class II (D/K/N) [IPR004364]", "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "Aminoacyl-tRNA synthetase, class II [IPR006195]", "Aminoacyl-tRNA synthetase, class Ia [IPR002300]", "Aminoglycoside phosphotransferase [IPR002575]", "Aminomethyltransferase, folate-binding domain [IPR006222]", "Aminopeptidase N-like , N-terminal domain [IPR045357]", "Aminopeptidase P [IPR033740]", "Aminopeptidase P, N-terminal [IPR007865]", "Aminotransferase class V domain [IPR000192]", "Aminotransferase, class I/classII [IPR004839]", "Amyloidogenic glycoprotein, E2 domain [IPR024329]", "Amyloidogenic glycoprotein, amyloid-beta peptide [IPR013803]", "Amyloidogenic glycoprotein, copper-binding [IPR011178]", "Amyloidogenic glycoprotein, extracellular [IPR008154]", "Amyloidogenic glycoprotein, heparin-binding [IPR015849]", "Anaphase-promoting complex subunit 1, C-terminal [IPR041221]", "Anaphase-promoting complex subunit 2, C-terminal [IPR014786]", "Anaphase-promoting complex subunit 4 long domain [IPR024790]", "Anaphase-promoting complex subunit 4, WD40 domain [IPR024977]", "Anaphase-promoting complex subunit 5 domain [IPR026000]", "Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]", "Angiomotin, C-terminal [IPR024646]", "Anillin homology domain [IPR012966]", "Anillin, N-terminal domain [IPR031970]", "Anillin, PH domain [IPR037840]", "Anion-transporting ATPase-like domain [IPR025723]", "Ankyrin repeat and LEM domain-containing protein 2, LEM domain [IPR035006]", "Ankyrin, UPA domain [IPR040745]", "Ankyrin-3, death domain [IPR037971]", "Anoctamin, dimerisation domain [IPR032394]", "Anticodon-binding [IPR004154]", "Anticodon-binding domain [IPR019181]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal [IPR006190]", "ApaG domain [IPR007474]", "Apoptosis-antagonizing transcription factor, C-terminal [IPR012617]", "Archaeal primase DnaG/twinkle, TOPRIM domain [IPR034154]", "Arf GTPase activating protein [IPR001164]", "Arfaptin homology (AH) domain [IPR010504]", "Arginine N-methyltransferase 2-like domain [IPR026480]", "Arginyl tRNA synthetase N-terminal domain [IPR005148]", "Arginyl-tRNA synthetase, catalytic core domain [IPR035684]", "Ariadne domain [IPR045840]", "Armadillo repeat-containing domain [IPR006911]", "Armadillo-like helical domain-containing protein 3, C-terminal [IPR013636]", "Aromatic amino acid beta-eliminating lyase/threonine aldolase [IPR001597]", "Arrestin C-terminal-like domain [IPR011022]", "Arrestin-like, N-terminal [IPR011021]", "Asn/Gln amidotransferase [IPR018027]", "Asparagine synthase [IPR001962]", "Asparagine synthase, N-terminal domain [IPR033738]", "Aspartate/glutamate/uridylate kinase [IPR001048]", "Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain [IPR006131]", "Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding [IPR006132]", "Aspartic peptidase, DDI1-type [IPR019103]", "Aspartyl beta-hydroxylase/Triadin domain [IPR007943]", "Aspartyl/Glutamyl-tRNA(Gln) amidotransferase, subunit B/E, catalytic [IPR006075]", "Aspartyl/asparaginy/proline hydroxylase [IPR007803]", "Ataxin 2, SM domain [IPR025852]", "Ataxin-10 domain [IPR019156]", "Ataxin-2, C-terminal [IPR009818]", "Atg6, BARA domain [IPR040455]", "Atg6/beclin, coiled-coil domain [IPR041691]", "Aurora kinase A [IPR030611]", "Aurora-A binding [IPR015128]", "Autophagy-related, C-terminal [IPR015412]", "B-block binding subunit of TFIIIC [IPR007309]", "B-box, C-terminal [IPR003649]", "B-box-type zinc finger [IPR000315]", "B3/B4 tRNA-binding domain [IPR005146]", "B30.2/SPRY domain [IPR001870]", "BAAT/Acyl-CoA thioester hydrolase C-terminal [IPR014940]", "BAG domain [IPR003103]", "BAP29/BAP31, transmembrane domain [IPR040463]", "BAR domain [IPR004148]", "BAT2, N-terminal [IPR009738]", "BAZ2A/BAZ2B, bromodomain [IPR037374]", "BCAS3 domain [IPR022175]", "BCNT-C domain [IPR011421]", "BCS1, N-terminal [IPR014851]", "BDHCT [IPR012532]", "BEACH domain [IPR000409]", "BEN domain [IPR018379]", "BING4, C-terminal domain [IPR012952]", "BOP1, N-terminal domain [IPR012953]", "BP28, C-terminal domain [IPR012954]", "BRCA1, serine-rich domain [IPR025994]", "BRCT domain [IPR001357]", "BRICHOS domain [IPR007084]", "BRK domain [IPR006576]", "BRO1 domain [IPR004328]", "BSD domain [IPR005607]", "BTB/Kelch-associated [IPR011705]", "BTB/POZ domain [IPR000210]", "BTB/POZ domain-containing protein KCTD11/21, C-terminal domain [IPR045763]", "BURAN domain [IPR045354]", "BZW1/2, W2 domain [IPR043510]", "Bacterial Ig-like, group 2 [IPR003343]", "Bacterial surface antigen (D15) [IPR000184]", "Band 3 cytoplasmic domain [IPR013769]", "Band 4.1 domain [IPR019749]", "Band 4.1, C-terminal [IPR008379]", "Band 7 domain [IPR001107]", "Band 7, C-terminal extension [IPR032435]", "Bap31/Bap29 cytoplasmic coiled-coil domain [IPR041672]", "Basic-leucine zipper domain [IPR004827]", "Bcr-Abl oncoprotein oligomerisation [IPR015123]", "Beclin-1, BH3 domain [IPR029318]", "Beta-Casp domain [IPR022712]", "Beta-adaptin appendage, C-terminal subdomain [IPR015151]", "Beta-amyloid precursor protein C-terminal [IPR019543]", "Beta-catenin-interacting ICAT domain [IPR009428]", "Beta-catenin-like protein 1, N-terminal [IPR013180]", "Beta-galactosidase jelly roll domain [IPR025300]", "Beta-hexosaminidase, eukaryotic type, N-terminal [IPR029019]", "Beta-ketoacyl synthase, C-terminal [IPR014031]", "Beta-ketoacyl synthase, N-terminal [IPR014030]", "Beta-lactamase-related [IPR001466]", "Bicarbonate transporter, C-terminal [IPR011531]", "Bifunctional delta 1-pyrroline-5-carboxylate synthetase, glutamate-5-kinase domain [IPR041744]", "Biliverdin reductase, catalytic [IPR015249]", "Bin3-type S-adenosyl-L-methionine binding domain [IPR024160]", "Biotin carboxylase, C-terminal [IPR005482]", "Biotin carboxylase-like, N-terminal domain [IPR005481]", "Biotin carboxylation domain [IPR011764]", "Biotin protein ligase, C-terminal [IPR003142]", "Biotin-protein ligase, N-terminal [IPR019197]", "Biotin/lipoyl attachment [IPR000089]", "Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL), catalytic domain [IPR004143]", "Bloom syndrome protein, BDHCT-box associated domain [IPR032439]", "Bloom syndrome protein, N-terminal domain [IPR032437]", "Bms1/Tsr1-type G domain [IPR030387]", "Borealin, N-terminal [IPR018851]", "Branched-chain alpha-ketoacid dehydrogenase kinase/Pyruvate dehydrogenase kinase, N-terminal [IPR018955]", "Brdt, bromodomain, repeat I [IPR043508]", "Brdt, bromodomain, repeat II [IPR043509]", "Brix domain [IPR007109]", "Bromo adjacent homology (BAH) domain [IPR001025]", "Bromodomain [IPR001487]", "Bromodomain adjacent to zinc finger domain protein 1A, bromodomain [IPR037325]", "Bromodomain protein 4, C-terminal [IPR031354]", "Brr2, N-terminal helicase PWI domain [IPR041094]", "Bud22 domain [IPR015158]", "Butyrophylin-like, SPRY domain [IPR003879]", "C-CAP/cofactor C-like domain [IPR017901]", "C-terminal associated domain of TOPRIM [IPR031660]", "C-type lectin-like [IPR001304]", "C2 DOCK-type domain [IPR027007]", "C2 domain [IPR000008]", "C2 phosphatidylinositol 3-kinase-type domain [IPR002420]", "C2CD5, C2 domain [IPR037785]", "C4-type zinc-finger of DNA polymerase delta [IPR025687]", "CAAX prenyl protease 1, N-terminal [IPR032456]", "CALCOCO1/2, zinc finger UBZ1-type [IPR041641]", "CAP Gly-rich domain [IPR000938]", "CAPN2, penta-EF hand, calcium binding motif [IPR042736]", "CARG-binding factor, N-terminal [IPR012956]", "CARP motif [IPR006599]", "CASK, SH3 domain [IPR035473]", "CBS domain [IPR000644]", "CCAAT-binding factor [IPR005612]", "CCD97-like, C-terminal [IPR040233]", "CCDC93, coiled-coil domain [IPR019159]", "CCR4-NOT transcription complex subunit 1, CAF1-binding domain [IPR032191]", "CCR4-NOT transcription complex subunit 1, HEAT repeat [IPR032194]", "CCR4-NOT transcription complex subunit 1, TTP binding domain [IPR032193]", "CCR4-NOT transcription complex subunit 1, domain 4 [IPR024557]", "CCR4-Not complex component, Not N-terminal domain [IPR007207]", "CCR4-Not complex component, Not1, C-terminal [IPR007196]", "CD2-associated protein, first SH3 domain [IPR035775]", "CD2-associated protein, second SH3 domain [IPR035776]", "CD2-associated protein, third SH3 domain [IPR035777]", "CD209-like, C-type lectin-like domain [IPR033989]", "CD47 immunoglobulin-like [IPR013270]", "CD47 transmembrane [IPR013147]", "CD80-like, immunoglobulin C2-set [IPR013162]", "CDC48, N-terminal subdomain [IPR003338]", "CDC48, domain 2 [IPR004201]", "CDH1/2, SANT-Helical linker 1 [IPR040793]", "CELF1/2, RNA recognition motif 1 [IPR034196]", "CELF1/2, RNA recognition motif 2 [IPR034198]", "CELF1/2, RNA recognition motif 3 [IPR034199]", "CENP-T/Histone H4, histone fold [IPR035425]", "CENP-V/GFA domain [IPR006913]", "CEP170, C-terminal [IPR029300]", "CFA20 domain [IPR007714]", "CHD subfamily II, SANT-like domain [IPR009462]", "CHD, C-terminal 2 [IPR012957]", "CHD, N-terminal [IPR012958]", "CHIP, N-terminal tetratricopeptide repeat domain [IPR041312]", "CHIP/LubX , U box domain [IPR045202]", "CHORD domain [IPR007051]", "CID domain [IPR006569]", "CIDE-N domain [IPR003508]", "CKK domain [IPR014797]", "CLASP N-terminal domain [IPR024395]", "CLU central domain [IPR033646]", "CLU domain [IPR025697]", "CNNM, transmembrane domain [IPR002550]", "CNOT4, RNA recognition motif [IPR034261]", "COMM domain [IPR017920]", "COMPASS complex Set1 subunit, N-SET domain [IPR024657]", "COP9 signalosome complex subunit 4, helix turn helix domain [IPR041406]", "COP9 signalosome complex subunit 7, helix I [IPR041481]", "COS domain [IPR017903]", "CP2 transcription factor [IPR007604]", "CPH domain [IPR021097]", "CPL domain [IPR012959]", "CPPED1, metallophosphatase domain [IPR041867]", "CPSF2, metallo-hydrolase domain [IPR035639]", "CPSF7, RNA recognition motif [IPR034773]", "CRA domain [IPR013144]", "CRAL-TRIO lipid binding domain [IPR001251]", "CRIB domain [IPR000095]", "CRK, C-terminal SH3 domain [IPR035458]", "CRK, N-terminal SH3 domain [IPR035457]", "CS domain [IPR007052]", "CSK-like, SH2 domain [IPR035027]", "CSN8/PSMD8/EIF3K [IPR033464]", "CTLH, C-terminal LisH motif [IPR006595]", "CTLH/CRA C-terminal to LisH motif domain [IPR024964]", "CTP synthase GATase domain [IPR033828]", "CTP synthase, N-terminal [IPR017456]", "CUB domain [IPR000859]", "CXC domain [IPR026489]", "CYRIA/CYRIB, Rac1 binding domain [IPR009828]", "Cadherin prodomain [IPR014868]", "Cadherin, N-terminal [IPR013164]", "Cadherin, cytoplasmic domain [IPR000233]", "Cadherin-like [IPR002126]", "Calcineurin-binding protein cabin-1, MEF2-binding domain [IPR015134]", "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]", "Calcineurin-like phosphoesterase domain, lpxH-type [IPR024654]", "Calcium binding and coiled-coil domain-like [IPR012852]", "Calcium uniporter protein, C-terminal [IPR006769]", "Calcium/calmodulin-dependent protein kinase II, association-domain [IPR013543]", "Calcyclin-binding Protein, CS domain [IPR037893]", "Calmodulin-regulated spectrin-associated protein, CH domain [IPR022613]", "Calpain C2 domain [IPR033884]", "Calpain subdomain III [IPR033883]", "Calponin homology domain [IPR001715]", "Calsyntenin, C-terminal [IPR045588]", "Caprin-1 dimerization domain [IPR041637]", "Carbamoyl-phosphate synthase large subunit, CPSase domain [IPR005483]", "Carbamoyl-phosphate synthase small subunit, GATase1 domain [IPR035686]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain [IPR002474]", "Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain [IPR005479]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain [IPR005480]", "Carbohydrate kinase PfkB [IPR011611]", "Carbon-nitrogen hydrolase [IPR003010]", "Carboxylase, conserved domain [IPR003379]", "Carboxypeptidase D, carboxypeptidase-like domain 2 [IPR034224]", "Carboxypeptidase D, carboxypeptidase-like domain 3 [IPR033848]", "Carnitine O-palmitoyltransferase, N-terminal [IPR032476]", "Casein kinase substrate, phosphoprotein PP28 [IPR019380]", "Caspase recruitment domain [IPR031964]", "Cathepsin C [IPR039412]", "Cathepsin C exclusion [IPR014882]", "Cation-transporting P-type ATPase, C-terminal [IPR006068]", "Cation-transporting P-type ATPase, N-terminal [IPR004014]", "Cationic amino acid transporter, C-terminal [IPR029485]", "Cdc23 [IPR007192]", "Cdc37, C-terminal [IPR013873]", "Cdc37, Hsp90 binding [IPR013874]", "Cdc37, N-terminal domain [IPR013855]", "Cell division control protein 73, C-terminal [IPR031336]", "Cell morphogenesis central region [IPR029473]", "Cell morphogenesis protein C-terminal [IPR025481]", "Cell morphogenesis protein N-terminal [IPR025614]", "Cellular tumor antigen p53, transactivation domain 2 [IPR040926]", "Centromere protein CENP-B, C-terminal domain [IPR015115]", "Centromere protein H, C-terminal [IPR008426]", "Centrosomal CEP44 domain [IPR029157]", "Centrosomal protein of 290kDa, coiled-coil region [IPR032321]", "Centrosomin, N-terminal motif 1 [IPR012943]", "Chaperone DnaJ, C-terminal [IPR002939]", "Chitinase II [IPR011583]", "Choline/carnitine acyltransferase domain [IPR039551]", "Choloylglycine hydrolase/NAAA C-terminal [IPR029132]", "Chromatin assembly factor 1 subunit B, C-terminal domain [IPR029129]", "Chromatin assembly factor 1 subunit p150, C-terminal [IPR029105]", "Chromatin assembly factor 1 subunit p150, N-terminal [IPR029091]", "Chromatin target of PRMT1 protein, C-terminal [IPR025715]", "Chromo domain [IPR023780]", "Chromo domain subgroup [IPR017984]", "Chromo shadow domain [IPR008251]", "Chromo/chromo shadow domain [IPR000953]", "Chromosome passenger complex (CPC) protein INCENP N-terminal [IPR022006]", "Circularly permuted (CP)-type guanine nucleotide-binding (G) domain [IPR030378]", "Citron homology (CNH) domain [IPR001180]", "Class I myosin tail homology domain [IPR010926]", "Class I myosin, motor domain [IPR036072]", "Class II PurE [IPR033626]", "Class II aldolase/adducin N-terminal [IPR001303]", "Class VI myosin, motor domain [IPR036114]", "Class XVIII myosin, motor domain [IPR036064]", "Clathrin adaptor, alpha-adaptin, appendage, C-terminal subdomain [IPR003164]", "Clathrin adaptor, alpha/beta/gamma-adaptin, appendage, Ig-like subdomain [IPR008152]", "Clathrin, heavy chain, linker, core motif [IPR015348]", "Clathrin/coatomer adaptor, adaptin-like, N-terminal [IPR002553]", "Cleavage and polyadenylation specificity factor 2, C-terminal [IPR025069]", "Cleavage stimulation factor subunit 1, dimerisation domain [IPR032028]", "Cleavage stimulation factor subunit 2, hinge domain [IPR025742]", "Cleavage/polyadenylation specificity factor, A subunit, C-terminal [IPR004871]", "Cleavage/polyadenylation specificity factor, A subunit, N-terminal [IPR018846]", "Clp ATPase, C-terminal [IPR019489]", "Clustered mitochondria protein, N-terminal [IPR028275]", "Clusterin, C-terminal [IPR016015]", "Clusterin, N-terminal [IPR016014]", "Cns1/TTC4, wheel domain [IPR044059]", "CoA-binding [IPR003781]", "Coagulation factor 5/8 C-terminal domain [IPR000421]", "Coatomer beta subunit, C-terminal [IPR011710]", "Coatomer beta subunit, appendage platform domain [IPR029446]", "Coatomer subunit gamma, C-terminal [IPR032154]", "Coatomer, WD associated region [IPR006692]", "Coatomer, alpha subunit, C-terminal [IPR010714]", "Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]", "Cobalamin (vitamin B12)-binding domain [IPR006158]", "Cobalamin (vitamin B12)-binding module, cap domain [IPR003759]", "Cobalamin adenosyltransferase-like [IPR016030]", "Coilin, N-terminal domain [IPR031722]", "Cold shock domain [IPR011129]", "Cold-shock (CSD) domain [IPR019844]", "Cold-shock protein, DNA-binding [IPR002059]", "Complex 1 LYR protein domain [IPR008011]", "Condensin complex subunit 1, C-terminal [IPR032682]", "Condensin complex subunit 1, N-terminal [IPR024324]", "Cop9 signalosome subunit 5 C-terminal domain [IPR040961]", "Copine, C-terminal [IPR010734]", "Copine, C2B domain [IPR037768]", "Core histone macro-H2A, macro domain [IPR035796]", "Cortactin, SH3 domain [IPR035716]", "Creatinase, N-terminal [IPR000587]", "Cro/C1-type helix-turn-helix domain [IPR001387]", "Cullin homology domain [IPR016158]", "Cullin protein, neddylation domain [IPR019559]", "Cullin, N-terminal [IPR001373]", "Cupin-like domain 8 [IPR041667]", "Cwf19-like protein, C-terminal domain-2 [IPR006767]", "Cwf19-like, C-terminal domain-1 [IPR006768]", "Cyclic nucleotide-binding domain [IPR000595]", "Cyclin-dependent kinase 11/PITSLRE, catalytic domain [IPR045267]", "Cyclin-like [IPR013763]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain [IPR002130]", "Cystatin domain [IPR000010]", "Cysteine-rich flanking region, C-terminal [IPR000483]", "Cystine knot, C-terminal [IPR006207]", "Cytidine and deoxycytidylate deaminase domain [IPR002125]", "Cytidyltransferase-like domain [IPR004821]", "Cytochrome C oxidase subunit II, transmembrane domain [IPR011759]", "Cytochrome b-c1 complex subunit Rieske, transmembrane domain [IPR004192]", "Cytochrome b5-like heme/steroid binding domain [IPR001199]", "Cytochrome c oxidase assembly factor 3, mitochondrial, coiled-coil domain [IPR018628]", "Cytochrome c oxidase subunit 2, C-terminal [IPR034210]", "Cytochrome c oxidase subunit I domain [IPR033944]", "Cytochrome c oxidase subunit II-like C-terminal [IPR002429]", "Cytochrome c oxidase, subunit II [IPR014222]", "Cytochrome c oxidase-like, subunit I domain [IPR023616]", "Cytoplasmic activation/proliferation-associated protein-1 C term [IPR022070]", "Cytoskeleton-associated protein 2, C-terminal [IPR029197]", "D-3-phosphoglycerate dehydrogenase, ASB domain [IPR045626]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain [IPR006140]", "D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain [IPR006139]", "DALR anticodon binding [IPR008909]", "DAMP1, SANT/Myb-like domain [IPR032563]", "DAZ-associated protein 1, RNA recognition motif 1 [IPR034134]", "DAZ-associated protein 1, RNA recognition motif 2 [IPR034131]", "DBC1/CARP1 catalytically inactive NUDIX hydrolase domain [IPR025954]", "DBINO domain [IPR020838]", "DBP10, C-terminal [IPR012541]", "DDE superfamily endonuclease domain [IPR004875]", "DDHD domain [IPR004177]", "DDT domain [IPR018501]", "DDX18/Has1, DEAD-box helicase domain [IPR044773]", "DDX41, DEAD-box helicase domain [IPR044113]", "DDX47/Rrp3, DEAD-box helicase domain [IPR044765]", "DDX52/Rok1, DEAD-box helicase domain [IPR044764]", "DEAD box protein 17, ATP-binding domain [IPR046330]", "DEAD/DEAH box helicase domain [IPR011545]", "DEAD2 [IPR010614]", "DEK, C-terminal [IPR014876]", "DEP domain [IPR000591]", "DET1- and DDB1-associated protein 1, N-terminal [IPR018276]", "DEUBAD domain [IPR044867]", "DFDF domain [IPR025762]", "DHHA1 domain [IPR003156]", "DHX15, DEXH-box helicase domain [IPR044756]", "DHX57, UBA domain [IPR042615]", "DHX8/ Prp22, DEXH-box helicase domain [IPR044762]", "DHX9, DEXH-box helicase domain [IPR044447]", "DHX9, first double-stranded RNA binding domain [IPR044445]", "DHX9, second double-stranded RNA binding domain [IPR044446]", "DIX domain [IPR001158]", "DJ-1/PfpI [IPR002818]", "DMAP1-binding domain [IPR010506]", "DML1/Misato, tubulin domain [IPR029209]", "DNA (cytosine-5)-methyltransferase 1, replication foci domain [IPR022702]", "DNA binding HTH domain, Psq-type [IPR007889]", "DNA damage inducible protein 1 ubiquitin-like domain [IPR033882]", "DNA fragmentation factor 45kDa, middle domain [IPR015121]", "DNA helicase, DnaB-like, C-terminal [IPR007694]", "DNA ligase 3, BRCT domain [IPR031916]", "DNA ligase, ATP-dependent, C-terminal [IPR012309]", "DNA ligase, ATP-dependent, N-terminal [IPR012308]", "DNA ligase, ATP-dependent, central [IPR012310]", "DNA methyltransferase 1-associated 1 [IPR008468]", "DNA mismatch repair protein MutS, C-terminal [IPR000432]", "DNA mismatch repair protein MutS, clamp [IPR007861]", "DNA mismatch repair protein MutS, connector domain [IPR007860]", "DNA mismatch repair protein MutS, core [IPR007696]", "DNA mismatch repair protein MutS-like, N-terminal [IPR007695]", "DNA mismatch repair protein family, N-terminal [IPR002099]", "DNA mismatch repair protein, S5 domain 2-like [IPR013507]", "DNA mitochondrial polymerase, exonuclease domain [IPR041336]", "DNA polymerase alpha catalytic subunit, N-terminal domain [IPR024647]", "DNA polymerase alpha catalytic subunit, catalytic domain [IPR045846]", "DNA polymerase alpha, subunit B, N-terminal [IPR013627]", "DNA polymerase alpha/delta/epsilon, subunit B [IPR007185]", "DNA polymerase delta subunit 2, C-terminal domain [IPR041863]", "DNA polymerase delta subunit, OB-fold domain [IPR040663]", "DNA polymerase epsilon subunit B, N-terminal [IPR024639]", "DNA polymerase epsilon, catalytic subunit A, C-terminal [IPR013697]", "DNA recombination and repair protein RecA, monomer-monomer interface [IPR020587]", "DNA repair Nbs1, C-terminal [IPR013908]", "DNA replication complex GINS protein SLD5, C-terminal [IPR031633]", "DNA replication factor RFC1, C-terminal [IPR013725]", "DNA topoisomerase 2, TOPRIM domain [IPR034157]", "DNA topoisomerase I, DNA binding, eukaryotic-type [IPR008336]", "DNA topoisomerase I, catalytic core, eukaryotic-type [IPR013500]", "DNA topoisomerase I, eukaryotic-type [IPR013499]", "DNA topoisomerase, type IIA, domain A [IPR002205]", "DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]", "DNA-binding RFX-type winged-helix domain [IPR003150]", "DNA-binding protein SMUBP-2, R3H domain [IPR034072]", "DNA-dependent protein kinase catalytic subunit, CC3 [IPR012582]", "DNA-dependent protein kinase catalytic subunit, CC5 [IPR045581]", "DNA-dependent protein kinase catalytic subunit, catalytic domain [IPR037706]", "DNA-directed DNA polymerase, family A, palm domain [IPR001098]", "DNA-directed DNA polymerase, family B, exonuclease domain [IPR006133]", "DNA-directed DNA polymerase, family B, multifunctional domain [IPR006134]", "DNA-directed RNA polymerase I subunit RPA2, domain 4 [IPR009674]", "DNA-directed RNA polymerase III subunit RPC1, C-terminal [IPR035698]", "DNA-directed RNA polymerase III subunit RPC1, N-terminal [IPR035697]", "DNA-directed RNA polymerase III subunit RPC5, C-terminal [IPR045576]", "DNA-directed RNA polymerase, N-terminal [IPR029262]", "DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]", "DNA-directed RNA polymerase, insert domain [IPR011262]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain [IPR007120]", "DNA-repair protein Xrcc1, N-terminal [IPR002706]", "DNA/RNA non-specific endonuclease [IPR001604]", "DNA/RNA-binding protein Alba-like [IPR002775]", "DNA/RNA-binding protein Kin17, WH-like domain [IPR019447]", "DNA2/NAM7 helicase, helicase domain [IPR041677]", "DNA2/NAM7 helicase-like, C-terminal [IPR041679]", "DOCKER domain [IPR027357]", "DPF1-3, N-terminal domain [IPR025750]", "DSBA-like thioredoxin domain [IPR001853]", "DTHCT [IPR012542]", "DWNN domain [IPR014891]", "DZF domain [IPR006561]", "Damage-control phosphatase ARMT1-like, metal-binding domain [IPR002791]", "Daxx, N-terminal Rassf1C-interacting domain [IPR031333]", "Dbl homology (DH) domain [IPR000219]", "Death domain [IPR000488]", "Dedicator of cytokinesis C, C2 domain [IPR037808]", "Dedicator of cytokinesis C/D, N-terminal [IPR021816]", "Dedicator of cytokinesis, N-terminal domain [IPR032376]", "Dehydrogenase, E1 component [IPR001017]", "Deoxynucleoside kinase domain [IPR031314]", "Desmoplakin, SH3 domain [IPR041615]", "Desmoplakin, spectrin-like domain [IPR041573]", "Deubiquitinating enzyme MINDY-3/4, conserved domain [IPR025257]", "DhaK domain [IPR004006]", "DhaL domain [IPR004007]", "Diacylglycerol kinase, catalytic domain [IPR001206]", "Diacylglycerol/phorbol-ester binding [IPR020454]", "Diaphanous autoregulatory (DAD) domain [IPR014767]", "Dicer dimerisation domain [IPR005034]", "Dicer, double-stranded RNA-binding domain [IPR044441]", "Dihydrofolate reductase domain [IPR001796]", "Dilute domain [IPR002710]", "Dip2-like domain [IPR037337]", "Dipeptidyl peptidase 8 /9 ,N-terminal [IPR045785]", "Dipeptidylpeptidase IV, N-terminal domain [IPR002469]", "Dis3-like cold-shock domain 2 [IPR041505]", "Dishevelled C-terminal [IPR024580]", "Dishevelled protein domain [IPR003351]", "Disintegrin domain [IPR001762]", "Disks Large homologue 3, SH3 domain [IPR035763]", "Disks large homologue 1, N-terminal PEST domain [IPR019590]", "Disulphide isomerase [IPR005788]", "DnaJ domain [IPR001623]", "DnaJ homolog subfamily C member 16, TRX domain [IPR043361]", "DnaJ homologue subfamily C, GRV2/DNAJC13, N-terminal domain [IPR045802]", "DnaJ-like protein C11, C-terminal [IPR024586]", "Dolichyldiphosphatase, PAP2 domain [IPR039667]", "Domain of unknown function DM14 [IPR006608]", "Domain of unknown function DUF1087 [IPR009463]", "Domain of unknown function DUF1115 [IPR010541]", "Domain of unknown function DUF155 [IPR003734]", "Domain of unknown function DUF1605 [IPR011709]", "Domain of unknown function DUF1731 [IPR013549]", "Domain of unknown function DUF1747 [IPR013719]", "Domain of unknown function DUF1899 [IPR015048]", "Domain of unknown function DUF1977, DnaJ-like [IPR015399]", "Domain of unknown function DUF3350 [IPR021785]", "Domain of unknown function DUF3385, target of rapamycin protein [IPR024585]", "Domain of unknown function DUF3456 [IPR021852]", "Domain of unknown function DUF3480 [IPR022557]", "Domain of unknown function DUF3517 [IPR021905]", "Domain of unknown function DUF3677 [IPR022145]", "Domain of unknown function DUF3699 [IPR022168]", "Domain of unknown function DUF382 [IPR007180]", "Domain of unknown function DUF4042 [IPR025283]", "Domain of unknown function DUF4149 [IPR025423]", "Domain of unknown function DUF4187 [IPR025239]", "Domain of unknown function DUF4208 [IPR025260]", "Domain of unknown function DUF4217 [IPR025313]", "Domain of unknown function DUF4371 [IPR025398]", "Domain of unknown function DUF4706 [IPR031600]", "Domain of unknown function DUF4749 [IPR031847]", "Domain of unknown function DUF5600 [IPR040990]", "Domain of unknown function DUF5604 [IPR040880]", "Domain of unknown function DUF5921 [IPR045803]", "Domain of unknown function DUF625 [IPR006887]", "Double-stranded RNA-binding domain [IPR014720]", "Down-regulated-in-metastasis protein [IPR011430]", "Drebrin-like protein, SH3 domain [IPR035717]", "Dual specificity phosphatase, catalytic domain [IPR000340]", "Dual specificity protein phosphatase domain [IPR020422]", "Dullard phosphatase domain, eukaryotic [IPR011948]", "Dynamin GTPase effector [IPR003130]", "Dynamin stalk domain [IPR000375]", "Dynamin, GTPase domain [IPR001401]", "Dynamin, N-terminal [IPR045063]", "Dynamin-like GTPase OPA1, C-terminal [IPR045817]", "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "Dynein associated protein [IPR022157]", "Dynein heavy chain AAA lid domain [IPR041658]", "Dynein heavy chain region D6 P-loop domain [IPR004273]", "Dynein heavy chain, AAA 5 extension domain [IPR041466]", "Dynein heavy chain, AAA module D4 [IPR024317]", "Dynein heavy chain, ATP-binding dynein motor region [IPR035706]", "Dynein heavy chain, C-terminal domain [IPR041228]", "Dynein heavy chain, coiled coil stalk [IPR024743]", "Dynein heavy chain, hydrolytic ATP-binding dynein motor region [IPR035699]", "Dynein heavy chain, linker [IPR013602]", "Dynein heavy chain, tail [IPR013594]", "Dyskerin-like [IPR012960]", "E2 binding [IPR014929]", "E3 ligase, CCCH-type zinc finger [IPR041367]", "E3 ubiquitin ligase EDD, ubiquitin-associated domain [IPR024725]", "E3 ubiquitin ligase UBR4, C-terminal [IPR025704]", "E3 ubiquitin ligase, domain of unknown function DUF908 [IPR010309]", "E3 ubiquitin ligase, domain of unknown function DUF913 [IPR010314]", "E3 ubiquitin-protein ligase AMFR, Ube2g2-binding region [IPR040675]", "E3 ubiquitin-protein ligase UBR4, N-terminal [IPR045841]", "EB1, C-terminal [IPR004953]", "EBP50, C-terminal [IPR015098]", "ECSIT, C-terminal domain [IPR029342]", "EF hand associated, type-1 [IPR013566]", "EF hand associated, type-2 [IPR013567]", "EF-hand domain [IPR002048]", "EF-hand domain, type 1 [IPR015153]", "EF-hand domain, type 2 [IPR015154]", "EF-hand, Ca insensitive [IPR014837]", "EFG, domain V [IPR035649]", "EGF-like calcium-binding domain [IPR001881]", "EGF-like domain [IPR000742]", "EGF-like domain, extracellular [IPR013111]", "EH domain [IPR000261]", "EH domain-containing protein, N-terminal [IPR031692]", "EIF2AK2, first double-stranded RNA binding domain [IPR044452]", "EIF2AK2, second double-stranded RNA binding domain [IPR044453]", "ELM2 domain [IPR000949]", "ELMO domain [IPR006816]", "ELMO, armadillo-like helical domain [IPR024574]", "ELYS, beta-propeller domain [IPR032040]", "ELYS-like domain [IPR025151]", "ENTH domain [IPR013809]", "ER membrane protein complex subunit 1, C-terminal [IPR011678]", "ER membrane protein complex subunit 7, beta-sandwich domain [IPR019008]", "ERAP1-like C-terminal domain [IPR024571]", "ERCC3/RAD25/XPB helicase, C-terminal domain [IPR032438]", "ERM family, FERM domain C-lobe [IPR041789]", "ERV/ALR sulfhydryl oxidase domain [IPR017905]", "ERdj5, C-terminal thioredoxin domain [IPR035674]", "ERdj5, first thioredoxin domain [IPR035673]", "ERp29, N-terminal [IPR012883]", "EVE domain [IPR002740]", "EWS, RNA recognition motif [IPR034869]", "EXPERA domain [IPR033118]", "EZH2, SET domain [IPR044439]", "Electron transfer flavoprotein, alpha subunit, C-terminal [IPR014731]", "Electron transfer flavoprotein, alpha subunit, N-terminal [IPR033947]", "Electron transfer flavoprotein, alpha/beta-subunit, N-terminal [IPR014730]", "Electron transfer flavoprotein, beta subunit, N-terminal [IPR033948]", "Elongation Factor G, domain II [IPR041095]", "Elongation factor 1 beta central acidic region, eukaryote [IPR018940]", "Elongation factor 1B gamma, C-terminal [IPR001662]", "Elongation factor 4, domain IV [IPR035654]", "Elongation factor EFG, domain V-like [IPR000640]", "Elongation factor G, domain III [IPR009022]", "Elongation factor Tu (EF-Tu), GTP-binding domain [IPR041709]", "Elongation factor Tu, domain 2 [IPR033720]", "Elp3/MiaB/NifB [IPR006638]", "Emerin, LEM domain [IPR034989]", "Endonuclease/exonuclease/phosphatase [IPR005135]", "Endophilin B2, SH3 domain [IPR035640]", "Endophilin-A, SH3 domain [IPR035824]", "Endophilin-B1, BAR domain [IPR035695]", "Endoplasmic reticulum resident protein 29, C-terminal [IPR011679]", "Endoplasmic reticulum resident protein 44, TRX-like domain b [IPR041870]", "Endoplasmic reticulum resident protein 44, TRX-like domain b' [IPR041862]", "Endoplasmic reticulum vesicle transporter, C-terminal [IPR012936]", "Endoplasmic reticulum vesicle transporter, N-terminal [IPR039542]", "EngB-type guanine nucleotide-binding (G) domain [IPR030393]", "Enhancer of mRNA-decapping protein 4, WD40 repeat region [IPR032401]", "Enolase, C-terminal TIM barrel domain [IPR020810]", "Enolase, N-terminal [IPR020811]", "Enoyl-CoA hydratase/isomerase domain [IPR045004]", "Ephrin receptor ligand binding domain [IPR001090]", "Ephrin receptor, transmembrane domain [IPR027936]", "Ephrin type-A receptor 7, ligand binding domain [IPR034283]", "Era-type guanine nucleotide-binding (G) domain [IPR030388]", "Ets domain [IPR000418]", "Eukaryotic Ribosomal Protein L27, KOW domain [IPR041991]", "Eukaryotic glycogen debranching enzyme, N-terminal domain [IPR029436]", "Eukaryotic translation initiation factor 2D, SUI1 domain [IPR039759]", "Eukaryotic translation initiation factor 3 subunit E, N-terminal [IPR019010]", "Eukaryotic translation initiation factor 3 subunit G, N-terminal [IPR024675]", "Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]", "Exocyst complex component Sec3, C-terminal [IPR019160]", "Exocyst complex component Sec3, PIP2-binding N-terminal domain [IPR028258]", "Exocyst component Exo84, C-terminal [IPR032403]", "Exonuclease 1-like, PIN-like domain [IPR044752]", "Exonuclease, RNase T/DNA polymerase III [IPR013520]", "Exonuclease-1, H3TH domain [IPR037315]", "Exoribonuclease, phosphorolytic domain 1 [IPR001247]", "Exoribonuclease, phosphorolytic domain 2 [IPR015847]", "Exosome complex component CSL4, C-terminal [IPR019495]", "Exosome complex component, N-terminal domain [IPR025721]", "Exosome complex exonuclease RRP44, S1 domain [IPR033770]", "Exosome-associated factor Rrp6, N-terminal [IPR012588]", "Exostosin, GT47 domain [IPR040911]", "Exportin-1, C-terminal [IPR014877]", "Exportin-1/Importin-beta-like [IPR013598]", "Exportin-2, C-terminal [IPR005043]", "Exportin-2, central domain [IPR013713]", "Exportin-5, C-terminal domain [IPR045478]", "Exportin-T, C-terminal domain [IPR045546]", "Extended PHD (ePHD) domain [IPR034732]", "Extended synaptotagmin, C-terminal C2 domain [IPR037752]", "Extended synaptotagmin, C2A domain [IPR037733]", "Extended synaptotagmin, C2B domain [IPR037749]", "Extracellular Endonuclease, subunit A [IPR020821]", "F-BAR domain [IPR031160]", "F-box domain [IPR001810]", "FACT complex subunit POB3-like, N-terminal PH domain [IPR035417]", "FACT complex subunit Spt16 domain [IPR013953]", "FACT complex subunit Spt16, N-terminal lobe domain [IPR029148]", "FACT complex subunit Spt16, peptidase M24-like domain [IPR033825]", "FAD dependent oxidoreductase [IPR006076]", "FAD dependent oxidoreductase, central domain [IPR032503]", "FAD linked oxidase, N-terminal [IPR006094]", "FAD-binding domain, PCMH-type [IPR016166]", "FAD-binding domain, ferredoxin reductase-type [IPR017927]", "FAD-dependent oxidoreductase 2, FAD binding domain [IPR003953]", "FAD-linked oxidase, C-terminal [IPR004113]", "FAD/NAD(P)-binding domain [IPR023753]", "FAF1, UBA-like domain [IPR044541]", "FAM3C (ILEI) domain [IPR039475]", "FAM69, protein-kinase domain [IPR022049]", "FAM91, C-terminal domain [IPR028097]", "FAM91, N-terminal domain [IPR028091]", "FANCI helical domain 1 [IPR029310]", "FANCI helical domain 2 [IPR029312]", "FANCI solenoid 1 cap [IPR029305]", "FANCI solenoid 1 domain [IPR029308]", "FANCI solenoid 2 domain [IPR029315]", "FANCI solenoid 3 domain [IPR029313]", "FANCI solenoid 4 domain [IPR029314]", "FAS-associated factor 1-like, UBX domain [IPR033043]", "FAST kinase leucine-rich [IPR010622]", "FAST kinase-like protein, subdomain 2 [IPR013579]", "FATC domain [IPR003152]", "FCH domain [IPR001060]", "FCP1 homology domain [IPR004274]", "FDF domain [IPR019050]", "FERM adjacent (FA) [IPR014847]", "FERM central domain [IPR019748]", "FERM domain [IPR000299]", "FERM, C-terminal PH-like domain [IPR018980]", "FERM, N-terminal [IPR018979]", "FF domain [IPR002713]", "FFD box [IPR025761]", "FGFR1 oncogene partner (FOP), N-terminal dimerisation domain [IPR018993]", "FHF complex subunit HOOK interacting protein, C-terminal [IPR045669]", "FHOD1, N-terminal GTPase-binding domain [IPR041387]", "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "FKBP12-rapamycin binding domain [IPR009076]", "FKBP3, basic tilted helix bundle domain [IPR041200]", "FUZ/MON1/HPS1, first Longin domain [IPR043972]", "FUZ/MON1/HPS1, second Longin domain [IPR043971]", "FUZ/MON1/HPS1, third Longin domain [IPR043970]", "FYVE zinc finger [IPR000306]", "Far upstream element-binding protein, C-terminal [IPR015096]", "Far11/STRP, C-terminal [IPR021819]", "Far11/STRP, N-terminal [IPR012486]", "Fascin domain [IPR022768]", "Fatty acid desaturase domain [IPR005804]", "Fatty acid hydroxylase [IPR006694]", "Fatty acyl-CoA reductase, C-terminal [IPR033640]", "Fatty acyl-coenzyme A reductase, NAD-binding domain [IPR013120]", "Fcf2 pre-rRNA processing, C-terminal [IPR014810]", "Ferrochelatase, C-terminal [IPR033644]", "Ferrochelatase, N-terminal [IPR033659]", "Fibronectin type II domain [IPR000562]", "Fibronectin type III [IPR003961]", "First polo-box domain [IPR033701]", "Flavodoxin-like [IPR001094]", "Flavodoxin/nitric oxide synthase [IPR008254]", "Flavoprotein pyridine nucleotide cytochrome reductase [IPR001709]", "Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain [IPR008333]", "Follistatin-like, N-terminal [IPR003645]", "Forkhead-associated (FHA) domain [IPR000253]", "Formin, FH2 domain [IPR015425]", "Formin, FH3 domain [IPR010472]", "Formin, GTPase-binding domain [IPR010473]", "Formin-binding protein 1, F-BAR domain [IPR037449]", "Formyl transferase, N-terminal [IPR002376]", "Fragile X-related 1 protein, C-terminal core [IPR022034]", "Fragile X-related 1 protein, C-terminal region 1 [IPR032172]", "Fragile X-related 1 protein, C-terminal region 3 [IPR032177]", "Fragile X-related mental retardation protein, C-terminal region 2 [IPR032196]", "Freud, C2 domain [IPR037772]", "Fumarase C, C-terminal [IPR018951]", "Fumarate lyase, N-terminal [IPR022761]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal [IPR015939]", "Fumarylacetoacetase, N-terminal [IPR015377]", "Fumarylacetoacetase-like, C-terminal [IPR011234]", "Fungal lipase-like domain [IPR002921]", "Fxr1, tudor domain [IPR041560]", "Fzo/mitofusin HR2 domain [IPR006884]", "G-patch domain [IPR000467]", "G-patch domain and KOW motifs-containing protein, KOW 1 [IPR041993]", "G-patch domain and KOW motifs-containing protein, KOW 2 [IPR041994]", "G-protein gamma-like domain [IPR015898]", "G-protein, beta subunit [IPR001632]", "G3BP1, RNA recognition motif [IPR034374]", "G3BP2, RNA recognition motif [IPR034376]", "GA-binding protein alpha subunit, N-terminal [IPR024668]", "GAD domain [IPR029351]", "GAR domain [IPR003108]", "GAT domain [IPR004152]", "GB1/RHD3-type guanine nucleotide-binding (G) domain [IPR030386]", "GCC2, Rab binding domain [IPR032023]", "GCF, C-terminal [IPR022783]", "GDAP2, macro domain [IPR035793]", "GH15-like domain [IPR011613]", "GHMP kinase N-terminal domain [IPR006204]", "GHMP kinase, C-terminal domain [IPR013750]", "GINS complex protein Sld5, alpha-helical domain [IPR038749]", "GINS subunit, domain A [IPR021151]", "GMP phosphodiesterase, delta subunit [IPR008015]", "GMP synthase, C-terminal [IPR001674]", "GMP synthase, glutamine amidotransferase [IPR004739]", "GMP synthetase ATP pyrophosphatase domain [IPR025777]", "GNAT domain [IPR000182]", "GOLD domain [IPR009038]", "GPAT/DHAPAT, acyltransferase domain [IPR041728]", "GPI ethanolamine phosphate transferase 2, C-terminal [IPR045687]", "GPI ethanolamine phosphate transferase 2, N-terminal [IPR037674]", "GPR domain [IPR000965]", "GRAF2, SH3 domain [IPR035485]", "GRAM domain [IPR004182]", "GRASP-type PDZ domain [IPR024958]", "GRB2, C-terminal SH3 domain [IPR035643]", "GRB2, N-terminal SH3 domain [IPR035641]", "GRIP domain [IPR000237]", "GRSF-1, RNA recognition motif 1 [IPR034425]", "GRSF-1, RNA recognition motif 2 [IPR034424]", "GRSF-1, RNA recognition motif 3 [IPR034426]", "GTP binding domain [IPR006073]", "GTP binding protein 1-like, GTP-binding domain [IPR035531]", "GTP binding protein, second domain [IPR031662]", "GTP-binding protein LepA, C-terminal [IPR013842]", "GTP-binding protein TrmE, N-terminal [IPR018948]", "GTP1/OBG domain [IPR006169]", "GTPase effector domain [IPR020850]", "GUCT [IPR012562]", "GYF domain 2 [IPR025640]", "GYF domain [IPR003169]", "Galactokinase, N-terminal domain [IPR019539]", "Galactose mutarotase, N-terminal barrel [IPR031727]", "Galactosyltransferase, C-terminal [IPR027791]", "Galactosyltransferase, N-terminal [IPR027995]", "Galanin [IPR008174]", "Galanin message associated peptide (GMAP) [IPR013068]", "Galectin, carbohydrate recognition domain [IPR001079]", "Gamma tubulin complex component protein, N-terminal [IPR041470]", "Gamma tubulin complex component, C-terminal [IPR040457]", "Gamma-adaptin ear (GAE) domain [IPR008153]", "Gamma-glutamyl cyclotransferase-like [IPR013024]", "Gelsolin-like domain [IPR007123]", "Gfo/Idh/MocA-like oxidoreductase, N-terminal [IPR000683]", "Gid-type RING finger domain [IPR044063]", "GlmS/AgaS, SIS domain 1 [IPR035466]", "GlmS/FrlB, SIS domain 2 [IPR035490]", "Glucosamine/galactosamine-6-phosphate isomerase [IPR006148]", "Glucose-6-phosphate dehydrogenase, C-terminal [IPR022675]", "Glucose-6-phosphate dehydrogenase, NAD-binding [IPR022674]", "Glucosidase 2 subunit beta-like [IPR036607]", "Glucosidase II beta subunit, N-terminal [IPR028146]", "Glucosyltransferase 24, catalytic domain [IPR040497]", "Glutaminase, EF-hand domain [IPR041541]", "Glutamine amidotransferase [IPR017926]", "Glutamine amidotransferase type 2 domain [IPR017932]", "Glutamine-Leucine-Glutamine, QLQ [IPR014978]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain 2 [IPR007638]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal [IPR007639]", "Glutamyl-tRNA synthetase [IPR033910]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, anti-codon binding domain [IPR020059]", "Glutamyl/glutaminyl-tRNA synthetase, class Ib, catalytic domain [IPR020058]", "Glutaredoxin [IPR002109]", "Glutaredoxin subgroup [IPR014025]", "Glutaredoxin, PICOT-like [IPR033658]", "Glutaredoxin, eukaryotic/virial [IPR011899]", "Glutathione S-transferase, C-terminal [IPR004046]", "Glutathione S-transferase, C-terminal-like [IPR010987]", "Glutathione S-transferase, N-terminal [IPR004045]", "Glutathione S-transferases, class Zeta , C-terminal [IPR034330]", "Glutathione S-transferases, class Zeta , N-terminal [IPR034333]", "Glutathione synthase, substrate-binding domain [IPR004887]", "Glyceraldehyde 3-phosphate dehydrogenase, NAD(P) binding domain [IPR020828]", "Glyceraldehyde 3-phosphate dehydrogenase, catalytic domain [IPR020829]", "Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]", "Glycerophosphodiester phosphodiesterase domain [IPR030395]", "Glycine cleavage T-protein, C-terminal barrel domain [IPR013977]", "Glycogen debranching enzyme, C-terminal [IPR032790]", "Glycogen debranching enzyme, central domain [IPR032788]", "Glycogen debranching enzyme, glucanotransferase domain [IPR032792]", "Glycogen synthase kinase 3, catalytic domain [IPR039192]", "Glycolipid transfer protein domain [IPR014830]", "Glycoside hydrolase 35, catalytic domain [IPR031330]", "Glycoside hydrolase family 18, catalytic domain [IPR001223]", "Glycoside hydrolase family 2, catalytic domain [IPR006103]", "Glycoside hydrolase family 20, catalytic domain [IPR015883]", "Glycoside hydrolase family 31, N-terminal domain [IPR025887]", "Glycoside hydrolase family 38, N-terminal domain [IPR000602]", "Glycoside hydrolase family 38, central domain [IPR015341]", "Glycoside hydrolase, family 2, immunoglobulin-like beta-sandwich [IPR006102]", "Glycosyl hydrolase family 30, TIM-barrel domain [IPR033453]", "Glycosyl hydrolase family 30, beta sandwich domain [IPR033452]", "Glycosyl hydrolase family 38, C-terminal [IPR011682]", "Glycosyl hydrolase family 63, C-terminal [IPR031335]", "Glycosyl hydrolase family 63, N-terminal [IPR031631]", "Glycosyl hydrolase, family 13, catalytic domain [IPR006047]", "Glycosyl hydrolases family 2, sugar binding domain [IPR006104]", "Glycosyl hydrolases family 38, C-terminal beta sandwich domain [IPR041147]", "Glycosyl transferase 64 domain [IPR015338]", "Glycosyl transferase CAP10 domain [IPR006598]", "Glycosyl transferase, family 1 [IPR001296]", "Glycosyltransferase 2-like [IPR001173]", "Glycyl-tRNA synthetase-like core domain [IPR033731]", "Glyoxalase domain-containing protein 4, C-terminal [IPR043194]", "Glyoxalase/fosfomycin resistance/dioxygenase domain [IPR004360]", "Golgi pH regulator, conserved domain [IPR022535]", "Golgin subfamily A, conserved domain [IPR043976]", "Groucho/TLE, N-terminal Q-rich domain [IPR005617]", "Growth hormone-inducible transmembrane protein [IPR035871]", "Guanine nucleotide exchange factor, N-terminal [IPR032691]", "Guanine nucleotide-binding protein-like 3, N-terminal domain [IPR014813]", "Guanylate kinase-like domain [IPR008144]", "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "Guanylate-binding protein, N-terminal [IPR015894]", "Guanylate-binding protein/Atlastin, C-terminal [IPR003191]", "HAD-superfamily hydrolase, subfamily IIID [IPR011943]", "HAD-superfamily hydrolase,subfamily IIIA [IPR006549]", "HAT, C-terminal dimerisation domain [IPR008906]", "HAUS augmin-like complex subunit 3, N-terminal [IPR032733]", "HAUS augmin-like complex subunit 6, N-terminal [IPR028163]", "HBS1-like protein, N-terminal [IPR015033]", "HCLS1-binding protein 3, PX domain [IPR037901]", "HD domain [IPR006674]", "HD/PDEase domain [IPR003607]", "HDGF-related, PWWP domain [IPR035496]", "HECT domain [IPR000569]", "HELLS, N-terminal [IPR044753]", "HELP [IPR005108]", "HERC2, APC10 domain [IPR037976]", "HERC2, zinc finger, ZZ-type [IPR041987]", "HHH domain 9 [IPR041692]", "HIRAN domain [IPR014905]", "HIT-like domain [IPR011146]", "HOOK, N-terminal [IPR043936]", "HORMA domain [IPR003511]", "HR1 rho-binding domain [IPR011072]", "HRDC domain [IPR002121]", "HSPA4, nucleotide-binding domain [IPR042052]", "HSPA4L, nucleotide-binding domain [IPR042708]", "HSPH1, nucleotide-binding domain [IPR042053]", "HTH CenpB-type DNA-binding domain [IPR006600]", "HTTM [IPR011020]", "HUWE1, UBA domain [IPR041918]", "Heat shock 70kDa protein 14, nucleotide-binding domain [IPR042049]", "Heat shock chaperonin-binding [IPR006636]", "Heat shock protein DnaJ, cysteine-rich domain [IPR001305]", "Heat shock protein Hsp90, N-terminal [IPR020575]", "Helical and beta-bridge domain [IPR010643]", "Helicase Helix-turn-helix domain [IPR029491]", "Helicase XPB/Ssl2, N-terminal domain [IPR032830]", "Helicase domain [IPR007807]", "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "Helicase superfamily 1/2, ATP-binding domain, DinG/Rad3-type [IPR014013]", "Helicase, C-terminal [IPR001650]", "Helicase-associated domain [IPR007502]", "Helicase-like, DEXD box c2 type [IPR006554]", "Helicase/SANT-associated domain [IPR014012]", "Helicase/UvrB, N-terminal [IPR006935]", "Helix-hairpin-helix DNA-binding motif, class 1 [IPR003583]", "Helix-turn-helix DNA-binding domain of Spt6 [IPR028088]", "Hemimethylated DNA-binding domain [IPR011722]", "Heparinase II, N-terminal [IPR032518]", "Hepatitis delta antigen (HDAg) domain [IPR037517]", "Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain [IPR024641]", "Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 1 [IPR034544]", "Heterogeneous nuclear ribonucleoprotein Q, RNA recognition motif 2 [IPR034548]", "Heterogeneous nuclear ribonucleoprotein R, RNA recognition motif 2 [IPR034411]", "Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]", "Hexokinase, C-terminal [IPR022673]", "Hexokinase, N-terminal [IPR022672]", "HhH-GPD domain [IPR003265]", "High mobility group box domain 5 [IPR029215]", "High mobility group box domain [IPR009071]", "Histidine kinase domain [IPR005467]", "Histidine kinase/HSP90-like ATPase [IPR003594]", "Histone H2A, C-terminal domain [IPR032454]", "Histone H2A/H2B/H3 [IPR007125]", "Histone acetyl transferase HAT1 N-terminal [IPR019467]", "Histone acetyltransferase domain, MYST-type [IPR002717]", "Histone deacetylase complex subunit SAP30 zinc-finger [IPR025717]", "Histone deacetylase complex subunit SAP30, Sin3 binding domain [IPR025718]", "Histone deacetylase domain [IPR023801]", "Histone deacetylase interacting domain [IPR013194]", "Histone methyltransferase, Tudor domain 1 [IPR041291]", "Histone methyltransferase, Tudor domain 2 [IPR041292]", "Histone-arginine methyltransferase CARM1, N-terminal [IPR020989]", "Histone-binding protein RBBP4, N-terminal [IPR022052]", "HnRNP M, nuclear localisation signal [IPR024666]", "Homeobox domain [IPR001356]", "Homocysteine-binding domain [IPR003726]", "Hook, C-terminal [IPR008636]", "Hotdog acyl-CoA thioesterase (ACOT)-type domain [IPR033120]", "HuR, RNA recognition motif 2 [IPR034996]", "Huntingtin-interacting protein 1, clathrin-binding domain [IPR032422]", "Hyaluronan-mediated motility receptor, C-terminal [IPR031794]", "Hyaluronan/mRNA-binding protein [IPR006861]", "Hydroxymethylglutaryl-coenzyme A synthase, C-terminal domain [IPR013746]", "Hydroxymethylglutaryl-coenzyme A synthase, N-terminal [IPR013528]", "Hypoxia induced protein, domain [IPR007667]", "I-kappa-kinase-beta NEMO binding domain [IPR022007]", "I/LWEQ domain [IPR002558]", "IBR domain [IPR002867]", "IF2a, S1-like domain [IPR044126]", "IGF2BP1, RNA recognition motif 1 [IPR034837]", "IGF2BP1, RNA recognition motif 2 [IPR034842]", "IGF2BP2, RNA recognition motif 1 [IPR034843]", "IGF2BP3, RNA recognition motif 2 [IPR034844]", "IKBKB, scaffold dimerization domain [IPR041185]", "ILEI/PANDER domain [IPR039477]", "IMD/I-BAR domain [IPR013606]", "IMP dehydrogenase/GMP reductase [IPR001093]", "IPS1, CARD domain [IPR042144]", "IPT domain [IPR002909]", "IRG-type guanine nucleotide-binding (G) domain [IPR030385]", "IRS-type PTB domain [IPR002404]", "IRSp53, SH3 domain [IPR035594]", "ISWI, HAND domain [IPR015194]", "Ima1, N-terminal domain [IPR018617]", "Immunoglobulin C1-set [IPR003597]", "Immunoglobulin I-set [IPR013098]", "Immunoglobulin V-set domain [IPR013106]", "Immunoglobulin [IPR013151]", "Immunoglobulin subtype 2 [IPR003598]", "Immunoglobulin subtype [IPR003599]", "Immunoglobulin-like domain [IPR007110]", "Impact, N-terminal [IPR001498]", "Importin-alpha, importin-beta-binding domain [IPR002652]", "Importin-beta, N-terminal domain [IPR001494]", "Initiation factor eIF-4 gamma, MA3 [IPR003891]", "Initiation factor eIF2 gamma, C-terminal [IPR015256]", "Initiation factor eIF2 gamma, GTP-binding domain [IPR044128]", "Initiation factor eIF2 gamma, domain 2 [IPR044127]", "Inner centromere protein, ARK-binding domain [IPR005635]", "Inositol 1,3,4-trisphosphate 5/6-kinase, ATP-grasp domain [IPR040464]", "Inositol polyphosphate 5-phosphatase, clathrin binding domain [IPR031995]", "Inositol polyphosphate-related phosphatase [IPR000300]", "Inositol-tetrakisphosphate 1-kinase, N-terminal [IPR041429]", "Integrator complex subunit 11, MBL-fold [IPR041897]", "Integrator complex subunit 14, C-terminal [IPR045814]", "Integrator complex subunit 3, N-terminal [IPR019333]", "Integrator complex subunit 5, C-terminal [IPR029444]", "Integrator complex subunit 5, N-terminal [IPR029445]", "Integrin alpha-2 [IPR013649]", "Integrin beta N-terminal [IPR033760]", "Integrin beta subunit, VWA domain [IPR002369]", "Integrin beta subunit, cytoplasmic domain [IPR014836]", "Integrin beta subunit, tail [IPR012896]", "Integrin beta, epidermal growth factor-like domain 1 [IPR040622]", "Integrin-linked protein kinase, pseudokinase domain [IPR035692]", "Interferon regulatory factor 2-binding protein 1 & 2, zinc finger [IPR022750]", "Intermediate filament head, DNA-binding domain [IPR006821]", "Intermediate filament, rod domain [IPR039008]", "Intersectin-2, fifth SH3 domain [IPR035741]", "Intersectin-2, first SH3 domain [IPR035737]", "Intersectin-2, fourth SH3 domain [IPR035740]", "Intersectin-2, second SH3 domain [IPR035738]", "Intersectin-2, third SH3 domain [IPR035739]", "Intracellular hyaluronan-binding protein 4, N-terminal domain [IPR032381]", "Intron-binding protein aquarius, N-terminal [IPR032174]", "Ion transporter-like, CBS domain [IPR044751]", "Iron sulphur domain-containing, mitoNEET, N-terminal [IPR019610]", "Iron-binding zinc finger, CDGSH type [IPR018967]", "Isochorismatase-like [IPR000868]", "Isoleucyl tRNA synthetase type 1, anticodon-binding domain [IPR033708]", "Isoleucyl tRNA synthetase type 2, anticodon-binding domain [IPR033709]", "Isopenicillin N synthase-like, Fe(2+) 2OG dioxygenase domain [IPR044861]", "Isopropylmalate dehydrogenase-like domain [IPR024084]", "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "JNK-interacting protein, leucine zipper II [IPR032486]", "JNK/Rab-associated protein-1, N-terminal [IPR019143]", "JmjC domain [IPR003347]", "Jumonji, helical domain [IPR041070]", "K Homology domain [IPR004087]", "K Homology domain, type 1 [IPR004088]", "K Homology domain, type 2 [IPR004044]", "KAP family P-loop domain [IPR011646]", "KASH domain [IPR012315]", "KELK-motif containing domain [IPR031597]", "KHDRBS, Qua1 domain [IPR032571]", "KN17, SH3-like C-terminal domain [IPR041330]", "KOW [IPR005824]", "Kin17, KOW domain [IPR041995]", "Kinase associated domain 1 (KA1) [IPR001772]", "Kindlin-2, N-terminal [IPR040790]", "Kindlin/fermitin, PH domain [IPR037837]", "Kinesin motor domain [IPR001752]", "Kinesin-associated microtubule-binding domain [IPR025901]", "Kinesin-like [IPR022164]", "Kinesin-like protein Kif23, Arf6-interacting domain [IPR032384]", "Kri1-like, C-terminal [IPR024626]", "Krr1, KH1 domain [IPR041174]", "Ku, C-terminal [IPR014893]", "Ku70/Ku80 C-terminal arm [IPR005160]", "Ku70/Ku80 beta-barrel domain [IPR006164]", "Ku70/Ku80, N-terminal alpha/beta [IPR005161]", "L1 transposable element, RRM domain [IPR043636]", "L1 transposable element, dsRBD-like domain [IPR035300]", "L1 transposable element, trimerization domain [IPR035301]", "L27 domain [IPR004172]", "L27 domain, C-terminal [IPR014775]", "L27-N [IPR015145]", "LAIKA domain [IPR045353]", "LARP4, RNA recognition motif [IPR034903]", "LARP5, RNA recognition motif [IPR034900]", "LARP7, RNA recognition motif 1 [IPR034887]", "LARP7, RNA recognition motif 2 [IPR034910]", "LEM domain [IPR003887]", "LEM-like domain [IPR013146]", "LETM1, ribosome-binding domain [IPR033122]", "LETM1-like [IPR011685]", "LIS1 homology motif [IPR006594]", "LRRC8, pannexin-like TM region [IPR021040]", "LSM domain, eukaryotic/archaea-type [IPR001163]", "LSM-interacting domain [IPR008669]", "LYRM2, LYR domain [IPR045293]", "La protein, xRRM domain [IPR014886]", "La-related protein 7, La domain [IPR034946]", "La-type HTH domain [IPR006630]", "Lactate/malate dehydrogenase, C-terminal [IPR022383]", "Lactate/malate dehydrogenase, N-terminal [IPR001236]", "Lamin tail domain [IPR001322]", "Lamin-B receptor of TUDOR domain [IPR019023]", "Lamina-associated polypeptide 2 alpha, C-terminal [IPR021623]", "Laminin G domain [IPR001791]", "Laminin IV [IPR000034]", "Laminin IV type B [IPR013015]", "Laminin, N-terminal [IPR008211]", "Laminin-type EGF domain [IPR002049]", "Large proline-rich protein BAG6 [IPR021925]", "Legume-like lectin [IPR005052]", "Lens epithelium-derived growth factor, integrase-binding domain [IPR021567]", "Lethal giant larvae homologue 2 [IPR013577]", "Leucine zipper, homeobox-associated [IPR003106]", "Leucine-rich repeat N-terminal domain [IPR000372]", "Leukocyte surface antigen CD47, IgV [IPR037805]", "Linker histone H1/H5, domain H15 [IPR005818]", "Liprin-alpha, SAM domain repeat 1 [IPR037620]", "Liprin-alpha, SAM domain repeat 2 [IPR037621]", "Liprin-alpha, SAM domain repeat 3 [IPR037622]", "Listerin, zinc finger, RING-type [IPR039804]", "Lon, substrate-binding domain [IPR003111]", "Longin domain [IPR010908]", "Lsm14-like, N-terminal [IPR025609]", "Lsm16, N-terminal [IPR034107]", "LsmAD domain [IPR009604]", "LysM domain [IPR018392]", "Lysine-specific demethylase 4, Tudor domain [IPR040477]", "Lysine-tRNA ligase, class II, N-terminal [IPR044136]", "Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]", "Lysyl-tRNA synthetase, class II, C-terminal [IPR018149]", "M60-like domain, N-terminal [IPR035423]", "MABP domain [IPR023341]", "MAGE homology domain [IPR002190]", "MAM domain [IPR000998]", "MAN1, RNA recognition motif [IPR034394]", "MANSC domain [IPR013980]", "MATH/TRAF domain [IPR002083]", "MCM N-terminal domain [IPR027925]", "MCM OB domain [IPR033762]", "MCM domain [IPR001208]", "MCM, AAA-lid domain [IPR041562]", "MD-2-related lipid-recognition domain [IPR003172]", "MDM2-binding protein, N-terminal domain [IPR029421]", "MDM2-binding protein, central domain [IPR029420]", "MDN2-binding protein, C-terminal domain [IPR029418]", "MEF-2, RNA recognition motif 1 [IPR034630]", "MEF-2, RNA recognition motif 3 [IPR034631]", "MENTAL domain [IPR019498]", "MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]", "MHC class I, alpha chain, C-terminal [IPR010579]", "MHC class I-like antigen recognition-like [IPR011161]", "MIA2, SH3 domain [IPR035555]", "MIF4G-like, type 1 [IPR015172]", "MIF4G-like, type 2 [IPR015174]", "MIF4G-like, type 3 [IPR003890]", "MIRO domain [IPR020860]", "MIT domain [IPR007330]", "MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding [IPR021043]", "MMS19, C-terminal [IPR024687]", "MMS19, N-terminal [IPR029240]", "MOSC, N-terminal beta barrel [IPR005303]", "MPN domain [IPR037518]", "MPP1, SH3 domain [IPR035475]", "MPP2, SH3 domain [IPR035602]", "MPP5, SH3 domain [IPR035601]", "MPP6, SH3 domain [IPR035603]", "MPP7, SH3 domain [IPR035599]", "MRG domain [IPR026541]", "MRH domain [IPR044865]", "MRPL44, double-stranded RNA binding domain [IPR044444]", "MST4, kinase domain [IPR035056]", "MTF2, PHD domain 1 [IPR042014]", "MTF2, PHD domain 2 [IPR042015]", "MYND-like zinc finger [IPR031615]", "MYST, zinc finger domain [IPR040706]", "Mab-21 domain [IPR024810]", "Macro domain [IPR002589]", "Macroglobulin domain MG3 [IPR041555]", "Macroglobulin domain [IPR002890]", "Mad3/Bub1 homology region 1 [IPR013212]", "Major facilitator superfamily domain [IPR020846]", "Major sperm protein (MSP) domain [IPR000535]", "Malectin domain [IPR021720]", "Malic enzyme, N-terminal domain [IPR012301]", "Malic enzyme, NAD-binding [IPR012302]", "Man1/Src1, C-terminal [IPR018996]", "Manganese/iron superoxide dismutase, C-terminal [IPR019832]", "Manganese/iron superoxide dismutase, N-terminal [IPR019831]", "Mannose-1-phosphate guanyltransferase, N-terminal domain [IPR045233]", "MaoC-like dehydratase domain [IPR002539]", "Marvel domain [IPR008253]", "Matrin-3, RNA recognition motif 1 [IPR034928]", "Matrin-3, RNA recognition motif 2 [IPR034930]", "Matrin/U1-C, C2H2-type zinc finger [IPR000690]", "Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]", "Mcm6, C-terminal winged-helix domain [IPR041024]", "Mediator complex, subunit Med1 [IPR019680]", "Mediator complex, subunit Med25, NR box [IPR021406]", "Mediator complex, subunit Med25, PTOV domain [IPR021394]", "Mediator complex, subunit Med25, synapsin 1 [IPR021397]", "Mediator of RNA polymerase II transcription subunit 25, von Willebrand factor type A domain [IPR021419]", "Membrane insertase YidC/Oxa1, C-terminal [IPR028055]", "Metallo-beta-lactamase [IPR001279]", "Metastasis-associated protein MTA1, R1 domain [IPR035170]", "Metaxin, glutathione S-transferase domain [IPR033468]", "Methionine synthase, B12-binding domain [IPR033706]", "Methionine--tRNA ligase, N-terminal [IPR041598]", "Methioninyl-tRNA synthetase core domain [IPR033911]", "Methionyl-tRNA synthetase, anticodon-binding domain [IPR041872]", "Methionyl/Leucyl tRNA synthetase [IPR015413]", "Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]", "Methyl-CpG DNA binding [IPR001739]", "Methyl-CpG binding protein 2/3, C-terminal domain [IPR025884]", "Methyl-CpG-binding domain protein 2/3, p55-binding region [IPR032343]", "Methylglyoxal synthase-like domain [IPR011607]", "Methylmalonyl-CoA mutase, C-terminal [IPR006159]", "Methylmalonyl-CoA mutase, alpha chain, catalytic [IPR006098]", "Methylmalonyl-CoA mutase, alpha/beta chain, catalytic [IPR006099]", "Methylthiotransferase, N-terminal [IPR013848]", "Methyltransferase domain 25 [IPR041698]", "Methyltransferase domain [IPR025714]", "Methyltransferase type 11 [IPR013216]", "Methyltransferase type 12 [IPR013217]", "Mff-like domain [IPR039433]", "Mib-herc2 [IPR010606]", "Micro-fibrillar-associated protein 1, C-terminal [IPR009730]", "Midasin AAA lid domain 5 [IPR041190]", "Midasin, AAA lid domain 7 [IPR040848]", "Midline-1, COS domain [IPR040859]", "Minichromosome loss protein Mcl1, middle region [IPR022100]", "Misato Segment II tubulin-like domain [IPR019605]", "Mitochondria fission protein Fis1, cytosolic domain [IPR033745]", "Mitochondrial ABC-transporter, N-terminal five TM domain [IPR032410]", "Mitochondrial apoptosis-inducing factor, C-terminal domain [IPR029324]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs [IPR034884]", "Mitochondrial degradasome RNA helicase subunit, C-terminal domain [IPR022192]", "Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]", "Mitochondrial ribosomal protein L46 NUDIX [IPR033650]", "MnmE, helical domain [IPR025867]", "MoaB/Mog domain [IPR001453]", "Modifier of rudimentary, Modr [IPR009851]", "MoeA, C-terminal, domain IV [IPR005111]", "MoeA, N-terminal and linker domain [IPR005110]", "Molybdenum cofactor sulfurase, C-terminal [IPR005302]", "Molybdenum cofactor synthesis C-terminal [IPR010505]", "Molybdopterin cofactor biosynthesis C (MoaC) domain [IPR002820]", "Molybdopterin oxidoreductase [IPR006656]", "Molybdopterin oxidoreductase, 4Fe-4S domain [IPR006963]", "Mon2, C-terminal [IPR032817]", "Mon2, dimerisation and cyclophilin-binding domain [IPR032629]", "Mre11 nuclease, N-terminal metallophosphatase domain [IPR041796]", "Mre11, DNA-binding [IPR007281]", "Mst1 SARAH domain [IPR024205]", "Mu homology domain [IPR028565]", "Mu2, C-terminal domain [IPR043512]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal [IPR031717]", "Multiple myeloma tumor-associated protein 2-like, N-terminal [IPR019315]", "Multiprotein bridging factor 1, N-terminal [IPR013729]", "Mvd1, C-terminal [IPR041431]", "Myb domain [IPR017930]", "Myc-type, basic helix-loop-helix (bHLH) domain [IPR011598]", "Myo-inositol-1-phosphate synthase, GAPDH-like [IPR013021]", "Myosin VI, cargo binding domain [IPR032412]", "Myosin head, motor domain [IPR001609]", "Myosin phosphatase-RhoA interacting protein, PH domain [IPR039597]", "Myosin tail [IPR002928]", "Myosin, N-terminal, SH3-like [IPR004009]", "Myosin-binding domain [IPR026859]", "Myotonic dystrophy protein kinase, coiled coil [IPR014930]", "Myristoyl-CoA:protein N-myristoyltransferase, C-terminal [IPR022677]", "Myristoyl-CoA:protein N-myristoyltransferase, N-terminal [IPR022676]", "N-acetylgalactosaminyltransferase [IPR045885]", "N-acetylneuraminic acid synthase, N-terminal [IPR013132]", "N-terminal extension of GAT domain [IPR041198]", "NAD(P) transhydrogenase, alpha subunit, C-terminal [IPR024605]", "NAD(P)-binding domain [IPR016040]", "NAD-dependent epimerase/dehydratase [IPR001509]", "NAD/GMP synthase [IPR022310]", "NADH dehydrogenase subunit 5, C-terminal [IPR010934]", "NADH pyrophosphatase-like, N-terminal [IPR015375]", "NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminal [IPR001516]", "NADH-quinone oxidoreductase, chain G, C-terminal [IPR015405]", "NADH-quinone oxidoreductase, subunit D [IPR001135]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain [IPR011538]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain [IPR019575]", "NADH:quinone oxidoreductase/Mrp antiporter, membrane subunit [IPR001750]", "NADH:ubiquinone oxidoreductase, 30kDa subunit [IPR001268]", "NADH:ubiquinone oxidoreductase, subunit G, iron-sulphur binding [IPR019574]", "NADH:ubiquinone oxidoreductase-like, 20kDa subunit [IPR006137]", "NADP transhydrogenase beta-like domain [IPR034300]", "NADP-dependent oxidoreductase domain [IPR023210]", "NDUFA6, LYR domain [IPR045299]", "NDUFB9, LYR domain [IPR045292]", "NECAP, PHear domain [IPR012466]", "NEDD8 ultimate buster 1, ubiquitin-like domain [IPR041207]", "NET domain [IPR027353]", "NF-kappaB-repression factor, R3H domain [IPR034071]", "NFACT protein, C-terminal [IPR021846]", "NFACT, RNA-binding domain [IPR008532]", "NGN domain [IPR005100]", "NGN domain, eukaryotic [IPR039385]", "NHL2, NHL repeat domain [IPR045302]", "NIF system FeS cluster assembly, NifU, C-terminal [IPR001075]", "NIPSNAP [IPR012577]", "NLE [IPR012972]", "NOG, C-terminal [IPR012973]", "NOG1, N-terminal helical domain [IPR041623]", "NOP5, N-terminal [IPR012974]", "NOPS [IPR012975]", "NOSIC [IPR012976]", "NOT2/NOT3/NOT5, C-terminal [IPR007282]", "NOT4, modified RING finger, HC subclass (C4C4-type) [IPR039515]", "NP60, PWWP domain [IPR035501]", "NPL4, zinc-binding putative [IPR007716]", "NSD, Cys-His rich domain [IPR041306]", "NT-type C2 domain [IPR019448]", "NUC153 [IPR012580]", "NUC205 domain [IPR012584]", "NUDE domain [IPR006964]", "NUDIX hydrolase [IPR020476]", "NUDIX hydrolase domain [IPR000086]", "NVL2, nucleolin binding domain [IPR031996]", "Nas2, N-terminal [IPR040815]", "Nascent polypeptide-associated complex NAC domain [IPR002715]", "Nck1, SH2 domain [IPR035882]", "Nck1, SH3 domain 1 [IPR035562]", "Nck1, SH3 domain 2 [IPR035564]", "Nck1, SH3 domain 3 [IPR035565]", "Negative elongation factor E, RNA recognition motif [IPR034637]", "Neurexin/syndecan/glycophorin C [IPR003585]", "Neurobeachin-like, DUF1088 [IPR010508]", "Neurobeachin/BDCP, DUF4704 [IPR031570]", "Neuroblastoma-amplified sequence, N-terminal [IPR029145]", "Neuropilin, C-terminal [IPR022579]", "Nibrin, second BRCT domain [IPR032429]", "Nicastrin, small lobe [IPR041084]", "Nicotinamide phosphoribosyltransferase, N-terminal domain [IPR041529]", "Nicotinate/nicotinamide phosphoribosyltransferase [IPR041525]", "Niemann-Pick C1, N-terminal [IPR032190]", "Nin one binding (NOB1) Zn-ribbon-like [IPR014881]", "Nischarin, PX domain [IPR037904]", "Nit1/2, carbon-nitrogen hydrolase domain [IPR045254]", "Nitric oxide synthase-interacting protein, zinc-finger [IPR031790]", "Nmd3, N-terminal [IPR007064]", "Non-canonical purine NTP phosphatase/PRRC1 [IPR026533]", "Nop domain [IPR002687]", "Nop2p [IPR011023]", "Notch domain [IPR000800]", "Notch, C-terminal [IPR024600]", "Notch, NOD domain [IPR010660]", "Notch, NODP domain [IPR011656]", "Novel protein kinase C delta, catalytic domain [IPR034667]", "Npc2 like, ML domain [IPR033916]", "Nrap protein domain 1 [IPR035082]", "Nrap protein, domain 2 [IPR035367]", "Nrap protein, domain 3 [IPR035368]", "Nrap protein, domain 4 [IPR035369]", "Nrap protein, domain 5 [IPR035370]", "Nrap protein, domain 6 [IPR035371]", "Nuclear RNA export factor Tap, RNA-binding domain [IPR015245]", "Nuclear condensin complex subunit 3, C-terminal domain [IPR025977]", "Nuclear migration protein nudC [IPR032572]", "Nuclear pore complex protein Nup214, phenylalanine-glycine (FG) domain [IPR041553]", "Nuclear pore complex, NUP2/50/61 [IPR015007]", "Nuclear pore localisation protein NPL4, C-terminal [IPR007717]", "Nuclear pore localisation protein Npl4, ubiquitin-like domain [IPR024682]", "Nuclear protein 96 [IPR021967]", "Nuclear transport factor 2 domain [IPR002075]", "Nuclear transport factor 2, eukaryote [IPR018222]", "Nuclear-interacting partner of ALK/Rsm1-like [IPR013909]", "Nucleolar GTP-binding protein 1, Rossman-fold domain [IPR010674]", "Nucleolar GTP-binding protein 2, N-terminal domain [IPR012971]", "Nucleolar complex-associated protein 3, N-terminal [IPR011501]", "Nucleolar protein 7, C-terminal [IPR012579]", "Nucleolar protein 8, RNA recognition motif [IPR034138]", "Nucleolin, RNA recognition motif 1 [IPR034230]", "Nucleolin, RNA recognition motif 2 [IPR034233]", "Nucleolin, RNA recognition motif 3 [IPR034234]", "Nucleolin, RNA recognition motif 4 [IPR034235]", "Nucleophosmin, C-terminal [IPR032569]", "Nucleoplasmin core domain [IPR024057]", "Nucleoporin Nup153, N-terminal [IPR013913]", "Nucleoporin Nup188, N-terminal [IPR018864]", "Nucleoporin Nup54, alpha-helical domain [IPR025712]", "Nucleoporin, NSP1-like, C-terminal [IPR007758]", "Nucleoporin, Nup133/Nup155-like, C-terminal [IPR007187]", "Nucleoporin, Nup133/Nup155-like, N-terminal [IPR014908]", "Nucleoprotein TPR/MLP1 [IPR012929]", "Nucleoredoxin, redox inactive TRX-like domain b' [IPR041861]", "Nucleoside diphosphate kinase-like domain [IPR034907]", "Nucleoside phosphorylase domain [IPR000845]", "Nucleotide exchange factor Fes1 [IPR013918]", "Nucleotidyl transferase domain [IPR005835]", "NudC N-terminal domain [IPR025934]", "NudC domain-containing protein 2, p23 domain [IPR037902]", "NudC domain-containing protein 3, p23 domain [IPR037905]", "NuoE domain [IPR042128]", "Nup358/RanBP2 E3 ligase domain [IPR022011]", "Nup54, C-terminal interacting domain [IPR040985]", "NusG, N-terminal [IPR006645]", "O-GlcNAc transferase, C-terminal [IPR029489]", "OB-fold nucleic acid binding domain, AA-tRNA synthetase-type [IPR004365]", "OBG-type guanine nucleotide-binding (G) domain [IPR031167]", "OCRE domain [IPR041591]", "OCRL1, PH domain [IPR037787]", "OCRL1/INPP5B, INPP5c domain [IPR037793]", "OTU domain [IPR003323]", "Occludin homology domain [IPR010844]", "Olduvai domain [IPR010630]", "Orc1-like, AAA ATPase domain [IPR041664]", "Origin recognition complex subunit 3, N-terminal [IPR045667]", "Origin recognition complex subunit 3, insertion domain [IPR045663]", "Origin recognition complex subunit 3, winged helix C-terminal [IPR040855]", "Orotate phosphoribosyl transferase domain [IPR004467]", "Orotidine 5'-phosphate decarboxylase domain [IPR001754]", "Ovarian carcinoma immunoreactive antigen domain [IPR009764]", "Oxidoreductase FAD/NAD(P)-binding [IPR001433]", "Oxidoreductase, N-terminal domain [IPR041694]", "Oxoglutarate/iron-dependent dioxygenase [IPR005123]", "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "P-type trefoil domain [IPR000519]", "PA domain [IPR003137]", "PABP, RNA recognition motif 2 [IPR045305]", "PACSIN1/PACSIN2, SH3 domain [IPR035743]", "PACSIN2, F-BAR domain [IPR037453]", "PADR1 domain [IPR012982]", "PAP/25A-associated [IPR002058]", "PARN, R3H domain [IPR034042]", "PAZ domain [IPR003100]", "PB1 domain [IPR000270]", "PDIP3, RNA recognition motif [IPR034784]", "PDZ domain 6 [IPR041489]", "PDZ domain [IPR001478]", "PDZ-associated domain of NMDA receptors [IPR019583]", "PET domain [IPR010442]", "PET testin [IPR033724]", "PH-BEACH domain [IPR023362]", "PHR [IPR012983]", "PI31 proteasome regulator, N-terminal [IPR021625]", "PI31 proteasome regulator, C-terminal [IPR013886]", "PI3K-C2-alpha, catalytic domain [IPR037705]", "PI4-kinase, N-terminal [IPR045495]", "PIK-related kinase [IPR014009]", "PIK-related kinase, FAT [IPR003151]", "PIN domain [IPR002716]", "PINIT domain [IPR023321]", "PITH domain [IPR010400]", "PKD domain [IPR000601]", "PKD/Chitinase domain [IPR022409]", "PLAA family ubiquitin binding domain [IPR015155]", "PLC-gamma, C-terminal SH2 domain [IPR035023]", "PLC-gamma, N-terminal SH2 domain [IPR035024]", "PLD-like domain [IPR032803]", "PNK, FHA domain [IPR041388]", "POLO box domain [IPR000959]", "POPLD domain [IPR012590]", "POTRA domain [IPR034746]", "PP2B, metallophosphatase domain [IPR041751]", "PP5, C-terminal metallophosphatase domain [IPR041753]", "PPIL4-like, cyclophilin domain [IPR035538]", "PPM-type phosphatase domain [IPR001932]", "PPP domain [IPR013235]", "PRELI/MSF1 domain [IPR006797]", "PRKAA2, UBA-like autoinhibitory domain [IPR028783]", "PRKCBP1, PHD finger [IPR044075]", "PRKRA, first double-stranded RNA binding domain [IPR044465]", "PRKRA, second double-stranded RNA binding domain [IPR044466]", "PRKRA, third double-stranded RNA binding domain [IPR044467]", "PRMT5 arginine-N-methyltransferase [IPR035075]", "PRMT5, TIM barrel domain [IPR035247]", "PRMT5, oligomerisation domain [IPR035248]", "PRO8NT domain [IPR012591]", "PROCN domain [IPR012592]", "PROCT domain [IPR012984]", "PRP1 splicing factor, N-terminal [IPR010491]", "PRP8 domain IV core [IPR021983]", "PSF, NOPS domain [IPR034526]", "PSF, RNA recognition motif 1 [IPR034525]", "PSI domain [IPR016201]", "PSP, proline-rich [IPR006568]", "PSP1, RNA recognition motif 1 [IPR034522]", "PSP1, RNA recognition motif 2 [IPR034523]", "PTB/PI domain [IPR006020]", "PTBP1, RNA recognition motif 1 [IPR035000]", "PTBP1, RNA recognition motif 2-like [IPR021790]", "PTBP1, RNA recognition motif 3 [IPR035001]", "PUA domain [IPR002478]", "PUB domain [IPR018997]", "PUF60, RNA recognition motif 1 [IPR034209]", "PUF60, RNA recognition motif 2 [IPR034211]", "PUF60, RNA recognition motif 3 [IPR034212]", "PUL domain [IPR013535]", "PWI domain [IPR002483]", "PWWP domain [IPR000313]", "Paf1 complex subunit Cdc73, N-terminal domain [IPR032041]", "Paired DNA-binding domain [IPR043182]", "Paired domain [IPR001523]", "Palladin, C-terminal immunoglobulin-like domain [IPR033017]", "Palmitoyltransferase, DHHC domain [IPR001594]", "Pancreatic trypsin inhibitor Kunitz domain [IPR002223]", "Patatin-like phospholipase domain [IPR002641]", "Pentacotripeptide-repeat region of PRORP [IPR033443]", "Pep3/Vps18/deep orange [IPR007810]", "Peptidase C12, C-terminal domain [IPR041507]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase [IPR001578]", "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "Peptidase C19, ubiquitin-specific peptidase, DUSP domain [IPR006615]", "Peptidase C1A, papain C-terminal [IPR000668]", "Peptidase C2, calpain, catalytic domain [IPR001300]", "Peptidase C2, calpain, domain III [IPR022683]", "Peptidase C2, calpain, large subunit, domain III [IPR022682]", "Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal [IPR015211]", "Peptidase M1, membrane alanine aminopeptidase [IPR014782]", "Peptidase M12B, ADAM/reprolysin [IPR001590]", "Peptidase M12B, propeptide [IPR002870]", "Peptidase M13, C-terminal domain [IPR018497]", "Peptidase M13, N-terminal domain [IPR008753]", "Peptidase M14, carboxypeptidase A [IPR000834]", "Peptidase M16, C-terminal [IPR007863]", "Peptidase M16, N-terminal [IPR011765]", "Peptidase M16, middle/third domain [IPR032632]", "Peptidase M16C associated [IPR013578]", "Peptidase M17, leucyl aminopeptidase, C-terminal [IPR000819]", "Peptidase M17, leucyl aminopeptidase, N-terminal [IPR008283]", "Peptidase M20, dimerisation domain [IPR011650]", "Peptidase M24 [IPR000994]", "Peptidase M24, C-terminal domain [IPR032416]", "Peptidase M28 [IPR007484]", "Peptidase M3A/M3B catalytic domain [IPR001567]", "Peptidase M41 [IPR000642]", "Peptidase M41, FtsH extracellular [IPR011546]", "Peptidase M48 [IPR001915]", "Peptidase S16, Lon proteolytic domain [IPR008269]", "Peptidase S24/S26A/S26B/S26C [IPR015927]", "Peptidase S26 [IPR019533]", "Peptidase S53, activation domain [IPR015366]", "Peptidase S54, rhomboid domain [IPR022764]", "Peptidase S59, nucleoporin [IPR007230]", "Peptidase S8/S53 domain [IPR000209]", "Peptidase S8A, tripeptidyl peptidase II [IPR022229]", "Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]", "Peptidase S9A, N-terminal domain [IPR023302]", "Peptidase family M60 domain [IPR031161]", "Peptide chain release factor class I [IPR000352]", "Peptidyl-prolyl cis-trans isomerase E, RNA recognition motif [IPR034168]", "Peptidyl-prolyl cis-trans isomerase like 2, U-box domain [IPR026951]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type [IPR000297]", "Pericentriolar material 1 protein, C-terminal [IPR031446]", "Peripheral subunit-binding domain [IPR004167]", "Peroxiredoxin, C-terminal [IPR019479]", "Peroxisome membrane anchor protein Pex14p, N-terminal [IPR006785]", "PheRS DNA binding domain 2 [IPR040586]", "PheRS, DNA binding domain 1 [IPR040724]", "PheRS, DNA binding domain 3 [IPR040725]", "Phenylacetic acid degradation-related domain [IPR003736]", "Phenylalanine--tRNA ligase beta subunit, B1 domain [IPR040659]", "Phenylalanyl tRNA synthetase beta chain, core domain [IPR041616]", "Phenylalanyl-tRNA synthetase [IPR002319]", "Phosducin, thioredoxin-like domain [IPR024253]", "Phosphatidic acid phosphatase type 2/haloperoxidase [IPR000326]", "Phosphatidylinositol 3-/4-kinase, catalytic domain [IPR000403]", "Phosphatidylinositol 3-kinase Ras-binding (PI3K RBD) domain [IPR000341]", "Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha, PX domain [IPR042133]", "Phosphatidylinositol-4-phosphate 5-kinase, core [IPR002498]", "Phosphatidylinositol-specific phospholipase C, X domain [IPR000909]", "Phosphoadenosine phosphosulphate reductase [IPR002500]", "Phosphoenolpyruvate carboxykinase, C-terminal P-loop domain [IPR035077]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, N-terminal [IPR035078]", "Phosphofructokinase domain [IPR000023]", "Phosphoglucose isomerase, SIS domain 1 [IPR035476]", "Phosphoglucose isomerase, SIS domain 2 [IPR035482]", "Phosphoinositide 3-kinase, accessory (PIK) domain [IPR001263]", "Phospholipase C, phosphatidylinositol-specific, Y domain [IPR001711]", "Phospholipase D-like domain [IPR025202]", "Phospholipase D/Transphosphatidylase [IPR001736]", "Phospholipase/carboxylesterase/thioesterase [IPR003140]", "Phospholipid/glycerol acyltransferase [IPR002123]", "Phosphopantetheine binding ACP domain [IPR009081]", "Phosphoribosylformylglycinamidine synthase, N-terminal [IPR040707]", "Phosphoribosylformylglycinamidine synthase, linker domain [IPR041609]", "Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain [IPR020561]", "Phosphoribosylglycinamide synthetase, C-domain [IPR020560]", "Phosphoribosylglycinamide synthetase, N-terminal [IPR020562]", "Phosphoribosyltransferase domain [IPR000836]", "Phosphoribulokinase/uridine kinase [IPR006083]", "Phosphorylase b kinase regulatory subunit alpha/beta, C-terminal domain [IPR045583]", "Phosphorylated adapter RNA export protein, RNA-binding domain [IPR019385]", "Phosphotyrosine protein phosphatase I [IPR023485]", "Phox homology [IPR001683]", "Pinin/SDK [IPR006787]", "Pinin/SDK/MemA protein [IPR006786]", "Pirin, C-terminal domain [IPR008778]", "Pirin, N-terminal domain [IPR003829]", "Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]", "Pleckstrin homology domain 8 [IPR041680]", "Pleckstrin homology domain 9 [IPR041681]", "Pleckstrin homology domain [IPR001849]", "Pleckstrin homology domain, spectrin-type [IPR001605]", "Plectin/S10, N-terminal [IPR005326]", "Plexin, TIG domain 1 [IPR041019]", "Plexin, cytoplasmic RasGAP domain [IPR013548]", "Plus-3 domain [IPR004343]", "Pointed domain [IPR003118]", "Polo-like kinase 1, catalytic domain [IPR033702]", "Poly(A) polymerase, RNA-binding domain [IPR007010]", "Poly(A) polymerase, central domain [IPR007012]", "Poly(A)-specific ribonuclease, RNA-binding [IPR014789]", "Poly(ADP-ribose) polymerase, catalytic domain [IPR012317]", "Poly(ADP-ribose) polymerase, regulatory domain [IPR004102]", "Polyadenylate-binding protein/Hyperplastic disc protein [IPR002004]", "Polyamine biosynthesis domain [IPR030374]", "Polycomb group protein, RNA binding region [IPR033763]", "Polycomb protein, VEFS-Box [IPR019135]", "Polycomb repressive complex 2 subunit EZH1/EZH2, tri-helical domain [IPR041343]", "Polycomb-like MTF2 factor 2, C-terminal domain [IPR025894]", "Polyketide synthase, C-terminal extension [IPR032821]", "Polyketide synthase, beta-ketoacyl synthase domain [IPR020841]", "Polyketide synthase, dehydratase domain [IPR020807]", "Polyketide synthase, enoylreductase domain [IPR020843]", "Polyketide synthase, ketoreductase domain [IPR013968]", "Polyketide synthase, phosphopantetheine-binding domain [IPR020806]", "Polymerase, nucleotidyl transferase domain [IPR002934]", "Polynucleotide 3'-phosphatase [IPR006551]", "Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2 [IPR034798]", "Polyribonucleotide 5'-hydroxyl-kinase Clp1, P-loop domain [IPR032319]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain [IPR015848]", "Polysaccharide biosynthesis domain [IPR021148]", "Pop1, N-terminal [IPR009723]", "Porphobilinogen deaminase, C-terminal [IPR022418]", "Porphobilinogen deaminase, N-terminal [IPR022417]", "Possible tRNA binding domain [IPR027992]", "Post-SET domain [IPR003616]", "Potassium channel tetramerisation-type BTB domain [IPR003131]", "Potentiating neddylation domain [IPR005176]", "Pre-PUA domain [IPR041366]", "Pre-SET CXC domain [IPR041355]", "Pre-SET domain [IPR007728]", "Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term [IPR021718]", "Pre-mRNA polyadenylation factor Fip1 domain [IPR007854]", "Pre-mRNA processing factor 4 (PRP4)-like [IPR014906]", "Pre-mRNA splicing factor component Cdc5p/Cef1, C-terminal [IPR021786]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding [IPR019581]", "Pre-mRNA-processing-splicing factor 8, U6-snRNA-binding [IPR019580]", "Pre-mRNA-splicing factor 19 [IPR013915]", "Pre-mRNA-splicing factor 3 [IPR013881]", "Pre-rRNA-processing protein Ipi1, N-terminal [IPR024679]", "Pre-rRNA-processing protein RIX1, N-terminal [IPR012583]", "Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal [IPR011945]", "Prenylcysteine lyase [IPR010795]", "Probable RNA-binding protein 19, RNA recognition motif 1 [IPR034418]", "Probable RNA-binding protein 19, RNA recognition motif 2 [IPR034417]", "Probable RNA-binding protein 19, RNA recognition motif 3 [IPR034419]", "Probable RNA-binding protein 19, RNA recognition motif 4 [IPR034420]", "Probable RNA-binding protein 19, RNA recognition motif 5 [IPR034423]", "Probable RNA-binding protein 19, RNA recognition motif 6 [IPR034421]", "Proliferating cell nuclear antigen, PCNA, C-terminal [IPR022649]", "Proliferating cell nuclear antigen, PCNA, N-terminal [IPR022648]", "Proline-tRNA ligase, class II, C-terminal [IPR016061]", "Prolyl 4-hydroxylase alpha subunit, Fe(2+) 2OG dioxygenase domain [IPR044862]", "Prolyl 4-hydroxylase alpha-subunit, N-terminal [IPR013547]", "Prolyl 4-hydroxylase, alpha subunit [IPR006620]", "Prolyl-tRNA synthetase, catalytic domain [IPR033721]", "Propionyl-coenzyme A carboxylase, BT domain [IPR041265]", "Prostaglandin E synthase 2, C-terminal [IPR034335]", "Proteasomal ATPase OB C-terminal domain [IPR032501]", "Proteasome activator Blm10, mid region [IPR032430]", "Proteasome activator PA28, C-terminal domain [IPR003186]", "Proteasome activator PA28, N-terminal domain [IPR003185]", "Proteasome activator complex subunit 4 C-terminal domain [IPR021843]", "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "Proteasome beta subunit, C-terminal [IPR024689]", "Proteasome component (PCI) domain [IPR000717]", "Protein HGH1 C-terminal [IPR007206]", "Protein HGH1 N-terminal [IPR007205]", "Protein Kinase B beta, catalytic domain [IPR034677]", "Protein Kinase B, pleckstrin homology domain [IPR039026]", "Protein O-mannosyl-transferase TMTC, DUF1736 [IPR013618]", "Protein OS9-like domain [IPR012913]", "Protein RED, C-terminal [IPR012492]", "Protein disulfide-isomerase A3, first redox inactive TRX-like domain b [IPR041868]", "Protein disulfide-isomerase A4, TRX-like domain b [IPR041866]", "Protein disulfide-isomerase A5, N-terminal TRX-like b domain [IPR041865]", "Protein furry, C-terminal [IPR045842]", "Protein kinase A anchor protein, nuclear localisation signal domain [IPR019510]", "Protein kinase B alpha, catalytic domain [IPR034676]", "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "Protein kinase domain [IPR000719]", "Protein kinase, C-terminal [IPR017892]", "Protein of unknown function DUF3504 [IPR021893]", "Protein of unknown function DUF3715 [IPR022188]", "Protein phosphatase 1 binding domain [IPR029334]", "Protein polybromo-1, Bromodomain 5 [IPR037968]", "Protein quaking, putative nuclear localisation signal [IPR032367]", "Protein-only RNase P, C-terminal [IPR031595]", "Protein-tyrosine phosphatase, catalytic [IPR003595]", "Protocadherin [IPR013585]", "Prp31 C-terminal [IPR019175]", "Pseudouridine synthase I, TruA, alpha/beta domain [IPR020097]", "Pseudouridine synthase II, N-terminal [IPR002501]", "Pseudouridine synthase, TruD, insertion domain [IPR011760]", "Pterin-binding domain [IPR000489]", "Pumilio homology domain [IPR033133]", "PurE domain [IPR000031]", "PurM-like, C-terminal domain [IPR010918]", "PurM-like, N-terminal domain [IPR016188]", "Putative 5-3 exonuclease [IPR004859]", "Putative RNA methylase domain [IPR000241]", "Putative RNA-binding protein 27, RNA recognition motif [IPR034451]", "Putative WW-binding domain and destruction box [IPR033461]", "Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain [IPR004099]", "Pyridoxamine 5'-phosphate oxidase, putative [IPR011576]", "Pyridoxamine kinase/Phosphomethylpyrimidine kinase [IPR013749]", "Pyridoxine 5'-phosphate oxidase, dimerisation, C-terminal [IPR019576]", "Pyrroline-5-carboxylate reductase, catalytic, N-terminal [IPR028939]", "Pyrroline-5-carboxylate reductase, dimerisation domain [IPR029036]", "Pyruvate carboxyltransferase [IPR000891]", "Pyruvate kinase, C-terminal [IPR015795]", "Pyruvate kinase, barrel [IPR015793]", "R3H domain [IPR001374]", "RABX5, catalytic core helical domain [IPR041545]", "RACK7, Bromo domain [IPR037967]", "RAD23A/RAD23B, UBA1 domain [IPR041811]", "RAD50, zinc hook [IPR013134]", "RAP domain [IPR013584]", "RAWUL domain [IPR032443]", "RBM10, OCRE domain [IPR035618]", "RBM12, RNA recognition motif 1 [IPR034591]", "RBM12, RNA recognition motif 2 [IPR034594]", "RBM12, RNA recognition motif 3 [IPR034855]", "RBM12, RNA recognition motif 4 [IPR034856]", "RBM12, RNA recognition motif 5 [IPR034854]", "RBM12B, RNA recognition motif 2 [IPR034588]", "RBM12B, RNA recognition motif 3 [IPR034858]", "RBM14, RNA recognition motif 1 [IPR034506]", "RBM14, RNA recognition motif 2 [IPR034507]", "RBM15, RNA recognition motif 1 [IPR034470]", "RBM15, RNA recognition motif 2 [IPR034472]", "RBM15, RNA recognition motif 3 [IPR034473]", "RBM1CTR [IPR012604]", "RBM25, RNA recognition motif [IPR034268]", "RBM26, RNA recognition motif 1 [IPR034859]", "RBM26-like, RNA recognition motif 2 [IPR039511]", "RBM3/CIRBP, RNA recognition motif [IPR034278]", "RBM34, RNA recognition motif 1 [IPR034220]", "RBM34, RNA recognition motif 2 [IPR034221]", "RBM4, RNA recognition motif 1 [IPR034897]", "RBM4, RNA recognition motif 2 [IPR034898]", "RBM42, RNA recognition motif [IPR034215]", "RBM45, RNA recognition motif 1 [IPR034203]", "RBM45, RNA recognition motif 2 [IPR034206]", "RBM45, RNA recognition motif 3 [IPR034207]", "RBM45, RNA recognition motif 4 [IPR034208]", "RBM6, OCRE domain [IPR035617]", "RBM6, RNA recognition motif 1 [IPR034123]", "RBM6, RNA recognition motif 2 [IPR034125]", "RBM7, RNA recognition motif [IPR034500]", "RBM8, RNA recognition motif [IPR033744]", "RDD [IPR010432]", "RED-like, N-terminal [IPR012916]", "REKLES domain [IPR023334]", "RFX1 transcription activation region [IPR007668]", "RH1 domain [IPR034743]", "RH2 domain [IPR034744]", "RHIM domain [IPR025735]", "RII binding domain [IPR018459]", "RING-type zinc-finger, LisH dimerisation motif [IPR027370]", "RIO kinase [IPR000687]", "RIO2 kinase winged helix domain, N-terminal [IPR015285]", "RIP1, Death domain [IPR037934]", "RL domain [IPR041252]", "RLI, domain 1 [IPR034348]", "RNA 2-O ribose methyltransferase, substrate binding [IPR013123]", "RNA 3'-terminal phosphate cyclase domain [IPR023797]", "RNA 3'-terminal phosphate cyclase, insert domain [IPR013791]", "RNA binding activity-knot of a chromodomain [IPR025995]", "RNA exonuclease 4, DEDDh 3'-5' exonuclease domain [IPR037431]", "RNA helicase UPF1, 1B domain [IPR040812]", "RNA helicase UPF1, Cys/His rich zinc-binding domain [IPR018999]", "RNA helicase, DEAD-box type, Q motif [IPR014014]", "RNA methyltransferase bin3, C-terminal [IPR010675]", "RNA polymerase II-associated protein 1, C-terminal [IPR013929]", "RNA polymerase II-associated protein 1, N-terminal [IPR013930]", "RNA polymerase III Rpc82, C -terminal [IPR008806]", "RNA polymerase III subunit RPC82-related, helix-turn-helix [IPR013197]", "RNA polymerase Rpb1, domain 1 [IPR007080]", "RNA polymerase Rpb1, domain 3 [IPR007066]", "RNA polymerase Rpb1, domain 4 [IPR007083]", "RNA polymerase Rpb1, domain 5 [IPR007081]", "RNA polymerase Rpb1, domain 6 [IPR007075]", "RNA polymerase Rpb1, domain 7 [IPR007073]", "RNA polymerase Rpb2, domain 2 [IPR007642]", "RNA polymerase Rpb2, domain 3 [IPR007645]", "RNA polymerase Rpb2, domain 4 [IPR007646]", "RNA polymerase Rpb2, domain 5 [IPR007647]", "RNA polymerase Rpb2, domain 7 [IPR007641]", "RNA polymerase Rpb4/RPC9, core [IPR006590]", "RNA polymerase Rpb7-like , N-terminal [IPR005576]", "RNA polymerase, N-terminal [IPR006592]", "RNA polymerase, Rpb5, N-terminal [IPR005571]", "RNA polymerase, alpha subunit [IPR000722]", "RNA polymerase, beta subunit, protrusion [IPR007644]", "RNA polymerase, subunit H/Rpb5 C-terminal [IPR000783]", "RNA recognition motif domain [IPR000504]", "RNA recognition motif domain, eukaryote [IPR003954]", "RNA recognition motif, spliceosomal PrP8 [IPR019582]", "RNA-binding S4 domain [IPR002942]", "RNA-binding domain, S1 [IPR022967]", "RNA-binding protein 10, RNA recognition motif 2 [IPR034992]", "RNA-binding protein 5, RNA recognition motif 1 [IPR034991]", "RNA-binding protein 5, RNA recognition motif 2 [IPR034993]", "RNA-binding protein Musashi homologue, RNA recognition motif 1 [IPR034130]", "RNA-binding protein Musashi homologue, RNA recognition motif 2 [IPR034126]", "RNA-polymerase II-associated protein 3-like, C-terminal domain [IPR025986]", "RNA-recognition motif (RRM) Nup35-type domain [IPR007846]", "RNPS1, RNA recognition motif [IPR034201]", "RNase L inhibitor RLI-like, possible metal-binding domain [IPR007209]", "ROCK, Rho binding domain [IPR015008]", "ROK, N-terminal [IPR012987]", "RPN1, N-terminal [IPR040892]", "RPN13, DEUBAD domain [IPR032368]", "RQC domain [IPR018982]", "RWD domain [IPR006575]", "RZZ complex, subunit KNTC1/ROD, C-terminal [IPR019527]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain [IPR009087]", "Rab-GTPase-TBC domain [IPR000195]", "Rab-binding domain FIP-RBD [IPR019018]", "Rab3-GAP regulatory subunit, N-terminal [IPR032839]", "Rab3GAP catalytic subunit, C-terminal [IPR045698]", "Rab3GAP catalytic subunit, conserved domain [IPR026147]", "Rab3GAP regulatory subunit, C-terminal [IPR029257]", "Rabaptin coiled-coil domain [IPR018514]", "Rabaptin, GTPase-Rab5 binding domain [IPR015390]", "Rad21/Rec8-like protein, C-terminal, eukaryotic [IPR006909]", "Rad21/Rec8-like protein, N-terminal [IPR006910]", "Rad50, ATP-binding cassette domain [IPR045171]", "Rad50/SbcC-type AAA domain [IPR038729]", "Rad60/SUMO-like domain [IPR022617]", "Radical SAM [IPR007197]", "Radical SAM, C-terminal extension [IPR032432]", "Raly, RNA recognition motif [IPR034502]", "Ran binding domain [IPR000156]", "Ran binding protein 9/10, SPRY domain [IPR035782]", "Ran-GTPase activating protein 1, C-terminal [IPR009109]", "Ran-specific GTPase-activating protein 1, Ran-binding domain [IPR045256]", "Rap1 Myb domain [IPR015010]", "Ras GTPase-activating domain [IPR001936]", "Ras guanine-nucleotide exchange factors catalytic domain [IPR001895]", "Ras-associating (RA) domain [IPR000159]", "Ras-like guanine nucleotide exchange factor, N-terminal [IPR000651]", "RasGAP protein, C-terminal [IPR000593]", "RecF/RecN/SMC, N-terminal [IPR003395]", "RecQ mediated genome instability protein, DUF1767 [IPR033472]", "RecQ mediated genome instability protein, N-terminal [IPR013894]", "Recq-mediated genome instability protein 1, C-terminal OB-fold domain [IPR032199]", "Redoxin [IPR013740]", "Regulator of G protein signalling-like domain [IPR015212]", "Replication factor A, C-terminal [IPR013955]", "Replication factor C, C-terminal [IPR013748]", "Replication factor-A protein 1, N-terminal [IPR007199]", "Replication protein A, C-terminal [IPR014892]", "Replication protein A, OB domain [IPR031657]", "Reticulon [IPR003388]", "Rho GTPase-activating protein domain [IPR000198]", "Rho GTPase-activating protein, FF domain [IPR032835]", "Rho GTPase-activating protein, pG1 and pG2 domain [IPR045786]", "Rho GTPase-activating protein, pG1 domain [IPR039007]", "Rho GTPase-activating protein, pG2 domain [IPR039006]", "Rho GTPase-binding/formin homology 3 (GBD/FH3) domain [IPR014768]", "Rho guanine nucleotide exchange factor 7, SH3 domain [IPR035789]", "Rho-associated protein kinase 1, HR1 [IPR037310]", "Rho-associated protein kinase 2, HR1 domain [IPR037311]", "Rhodanese-like domain [IPR001763]", "Riboflavin kinase domain, bacterial/eukaryotic [IPR015865]", "Ribonuclease H1, N-terminal [IPR011320]", "Ribonuclease HII/HIII domain [IPR024567]", "Ribonuclease II/R [IPR001900]", "Ribonuclease III domain [IPR000999]", "Ribonuclease, PIN domain [IPR033411]", "Ribonucleoprotein PTB-binding 1, RNA recognition motif 1 [IPR034633]", "Ribonucleotide reductase large subunit, C-terminal [IPR000788]", "Ribonucleotide reductase large subunit, N-terminal [IPR013509]", "Ribonucleotide reductase, class I , alpha subunit [IPR013346]", "Ribose-phosphate pyrophosphokinase, N-terminal domain [IPR029099]", "Ribosomal L28e/Mak16 [IPR029004]", "Ribosomal Protein L6, KOW domain [IPR041997]", "Ribosomal Proteins L2, RNA binding domain [IPR022666]", "Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]", "Ribosomal RNA methyltransferase FtsJ domain [IPR002877]", "Ribosomal RNA methyltransferase Spb1, domain of unknown function DUF3381 [IPR024576]", "Ribosomal RNA methyltransferase, Spb1, C-terminal [IPR012920]", "Ribosomal RNA small subunit methyltransferase F, N-terminal [IPR031341]", "Ribosomal RNA-processing protein 14/surfeit locus protein 6, C-terminal domain [IPR029190]", "Ribosomal RNA-processing protein 7, C-terminal domain [IPR024326]", "Ribosomal S6 kinase, N-terminal catalytic domain [IPR041906]", "Ribosomal protein 50S-L18Ae/60S-L20/60S-L18A [IPR023573]", "Ribosomal protein L10e/L16 [IPR016180]", "Ribosomal protein L11, C-terminal [IPR020783]", "Ribosomal protein L11, N-terminal [IPR020784]", "Ribosomal protein L14, KOW motif [IPR041985]", "Ribosomal protein L14e domain [IPR002784]", "Ribosomal protein L18e/L15P [IPR021131]", "Ribosomal protein L19, eukaryotic [IPR033935]", "Ribosomal protein L19/L19e [IPR000196]", "Ribosomal protein L2, C-terminal [IPR022669]", "Ribosomal protein L23/L25, N-terminal [IPR005633]", "Ribosomal protein L26/L24, KOW domain [IPR041988]", "Ribosomal protein L30, N-terminal [IPR012988]", "Ribosomal protein L30, ferredoxin-like fold domain [IPR016082]", "Ribosomal protein L46, N-terminal [IPR021757]", "Ribosomal protein L5 eukaryotic, C-terminal [IPR025607]", "Ribosomal protein L5, C-terminal [IPR031309]", "Ribosomal protein L5, N-terminal [IPR031310]", "Ribosomal protein L6, N-terminal [IPR005568]", "Ribosomal protein L6, alpha-beta domain [IPR020040]", "Ribosomal protein L7, eukaryotic/archaeal [IPR035808]", "Ribosomal protein L7/L12, C-terminal [IPR013823]", "Ribosomal protein L7/L12, oligomerisation [IPR008932]", "Ribosomal protein L7Ae/L30e/S12e/Gadd45 [IPR004038]", "Ribosomal protein L9, N-terminal [IPR020070]", "Ribosomal protein S10 domain [IPR027486]", "Ribosomal protein S13/S15, N-terminal [IPR012606]", "Ribosomal protein S23/S25, mitochondrial [IPR023611]", "Ribosomal protein S24/S35, mitochondrial, conserved domain [IPR019349]", "Ribosomal protein S3, C-terminal [IPR001351]", "Ribosomal protein S4, KOW domain [IPR041982]", "Ribosomal protein S4/S9, N-terminal [IPR001912]", "Ribosomal protein S4e, N-terminal [IPR013843]", "Ribosomal protein S4e, central region [IPR013845]", "Ribosomal protein S5, C-terminal [IPR005324]", "Ribosomal protein S5, N-terminal [IPR013810]", "Ribosomal protein S6 kinase alpha-3, C-terminal catalytic domain [IPR041905]", "Ribosomal protein S7 domain [IPR023798]", "Ribosomal protein/NADH dehydrogenase domain [IPR007741]", "Ribosome biogenesis protein BMS1/TSR1, C-terminal [IPR007034]", "Ribosome biogenesis protein Bms1, N-terminal [IPR037875]", "Ribosome maturation protein Sdo1/SBDS, C-terminal [IPR018978]", "Ribosome maturation protein Sdo1/SBDS, N-terminal [IPR019783]", "Ribosome receptor lysine/proline rich [IPR007794]", "Ribosome recycling factor domain [IPR023584]", "Ribosome-associated complex head domain [IPR032003]", "Ricin B, lectin domain [IPR000772]", "Rieske iron-sulphur protein, C-terminal [IPR005805]", "Right handed beta helix domain [IPR039448]", "RmlD-like substrate binding domain [IPR029903]", "Roadblock/LAMTOR2 domain [IPR004942]", "Rpa43, N-terminal ribonucleoprotein (RNP) domain [IPR041901]", "Rpn11/EIF3F, C-terminal [IPR024969]", "Rpn13/ADRM1, Pru domain [IPR044868]", "RrmJ-type ribose 2-O-methyltransferase domain [IPR025816]", "Rrp40, S1 domain [IPR037319]", "Rrp44-like cold shock domain [IPR033771]", "Rrp7, RRM-like N-terminal domain [IPR040447]", "Rrp7A, RNA recognition motif [IPR034890]", "RuvB-like, AAA-lid domain [IPR041048]", "S-adenosyl-L-homocysteine hydrolase, NAD binding domain [IPR015878]", "S-adenosylmethionine synthetase, C-terminal [IPR022630]", "S-adenosylmethionine synthetase, N-terminal [IPR022628]", "S-adenosylmethionine synthetase, central domain [IPR022629]", "S1 domain [IPR003029]", "S1-like RNA binding domain [IPR025223]", "S100/CaBP-9k-type, calcium binding, subdomain [IPR013787]", "SAB domain [IPR007477]", "SAC domain [IPR002013]", "SAC3/GANP/THP3, conserved domain [IPR005062]", "SAF domain [IPR013974]", "SAICAR synthetase/ADE2, N-terminal [IPR028923]", "SAM domain [IPR041418]", "SAM-dependent methyltransferase RsmB/NOP2-type [IPR001678]", "SANT domain [IPR017884]", "SANT/Myb domain [IPR001005]", "SAP domain [IPR003034]", "SARAH domain [IPR011524]", "SART3, RNA recognition motif 1 [IPR034217]", "SART3, RNA recognition motif 2 [IPR034218]", "SCAF4, RNA recognition motif [IPR034369]", "SCAF8, RNA recognition motif [IPR034370]", "SCP2 sterol-binding domain [IPR003033]", "SDA1 domain [IPR007949]", "SEC23-interacting protein, SAM domain [IPR037603]", "SEP domain [IPR012989]", "SERRATE/Ars2 , C-terminal [IPR007042]", "SERRATE/Ars2, N-terminal [IPR021933]", "SET domain [IPR001214]", "SF3A2 domain [IPR031781]", "SF3A3 domain [IPR031774]", "SF3B4, RNA recognition motif 1 [IPR034158]", "SF3B4, RNA recognition motif 2 [IPR034159]", "SF3B6, RNA recognition motif [IPR034150]", "SGF29 tudor-like domain [IPR010750]", "SGNH hydrolase-type esterase domain [IPR013830]", "SGS domain [IPR007699]", "SGTA, homodimerisation domain [IPR032374]", "SH2 domain [IPR000980]", "SH3 domain [IPR001452]", "SH3-like domain, bacterial-type [IPR003646]", "SHARP, RNA recognition motif 1 [IPR034172]", "SHARP, RNA recognition motif 2 [IPR034173]", "SHARP, RNA recognition motif 3 [IPR034174]", "SHARP, RNA recognition motif 4 [IPR034175]", "SIS domain [IPR001347]", "SKI-interacting protein SKIP, SNW domain [IPR004015]", "SKICH domain [IPR041611]", "SKP1 component, POZ domain [IPR016073]", "SKP1 component, dimerisation [IPR016072]", "SLC12A transporter, C-terminal [IPR018491]", "SLED domain [IPR021987]", "SLIDE domain [IPR015195]", "SLIRP, RNA recognition motif [IPR034152]", "SMAP1-like, ArfGAP domain [IPR044732]", "SMARCA1, N-terminal [IPR044755]", "SMARCC, C-terminal [IPR032451]", "SMARCC, N-terminal [IPR032450]", "SMARCC, SWIRM-associated domain [IPR032448]", "SMCs flexible hinge [IPR010935]", "SMG1, PIKK catalytic domain [IPR039414]", "SMYD3, SET domain [IPR044420]", "SNARE-complex protein Syntaxin-18, N-terminal [IPR019529]", "SNF2, N-terminal [IPR000330]", "SNX17, atypical FERM-like domain [IPR037836]", "SNX2, PX domain [IPR037918]", "SNX27, PX domain [IPR037833]", "SNX27, RA domain [IPR037835]", "SNX27, atypical FERM-like domain [IPR037827]", "SNX5, PX domain [IPR042135]", "SNX6, PX domain [IPR042136]", "SNX8/Mvp1, PX domain [IPR035704]", "SNX9, SH3 domain [IPR035558]", "SPF45, RNA recognition motif [IPR034653]", "SPIN90, SH3 domain [IPR035514]", "SPIN90/Ldb17, leucine-rich domain [IPR018556]", "SPRY domain [IPR003877]", "SPRY-associated [IPR006574]", "SR140, RNA recognition motif [IPR035009]", "SRA-YDG [IPR003105]", "SRCR domain [IPR001190]", "SRCR-like domain [IPR017448]", "SRP9 domain [IPR039432]", "SRSF1, RNA recognition motif 1 [IPR034520]", "SRSF6, RNA recognition motif 1 [IPR034511]", "SRSF7, RNA recognition motif [IPR034651]", "SRSF9, RNA recognition motif 1 [IPR034503]", "SRSF9, RNA recognition motif 2 [IPR034995]", "SSRP1 domain [IPR024954]", "STAG [IPR013721]", "STAM1, SH3 domain [IPR035657]", "STAMBP/STALP-like, MPN domain [IPR044098]", "STAR protein, homodimerisation region [IPR032377]", "STARD7, START domain [IPR041949]", "START domain [IPR002913]", "STAT transcription factor, DNA-binding [IPR013801]", "STAT transcription factor, all-alpha domain [IPR013800]", "STAT transcription factor, protein interaction [IPR013799]", "STAT1, SH2 domain [IPR035859]", "STAT3, SH2 domain [IPR035855]", "STI1 domain [IPR041243]", "STRBP, first double-stranded RNA binding domain [IPR044472]", "SUI1 domain [IPR001950]", "SUMO-activating enzyme subunit 2, C-terminal domain [IPR032426]", "SUN coiled coil domain 2 [IPR040994]", "SUN domain [IPR012919]", "SUN domain-containing protein 1, N-terminal [IPR032680]", "SUZ-C domain [IPR024642]", "SWAP/Surp [IPR000061]", "SWI/SNF-like complex subunit BAF250, C-terminal [IPR033388]", "SWIB domain [IPR019835]", "SWIB/MDM2 domain [IPR003121]", "SWIRM domain [IPR007526]", "Saccharopine dehydrogenase, NADP binding domain [IPR005097]", "Saccharopine dehydrogenase-like, C-terminal [IPR032095]", "Sam68, tyrosine-rich domain [IPR032335]", "Saposin A-type domain [IPR003119]", "Saposin B type domain [IPR008139]", "Saposin B type, region 2 [IPR008138]", "Saposin-like type B, region 1 [IPR007856]", "Scaffold protein Nfu/NifU, N-terminal [IPR014824]", "Schlafen group 3-like, DNA/RNA helicase domain [IPR018647]", "Schlafen, AlbA_2 domain [IPR007421]", "Sec16, central conserved domain [IPR024340]", "Sec23, C-terminal [IPR037550]", "Sec23/Sec24 beta-sandwich [IPR012990]", "Sec23/Sec24, helical domain [IPR006900]", "Sec23/Sec24, trunk domain [IPR006896]", "Sec24-like, trunk domain [IPR041742]", "Sec39 domain [IPR013244]", "Sec63 domain [IPR004179]", "Sec7 domain [IPR000904]", "Sec7, C-terminal [IPR015403]", "Sec8 exocyst complex component specific domain [IPR007191]", "Second polo-box domain [IPR033695]", "Sedolisin domain [IPR030400]", "Sema domain [IPR001627]", "Senescence/spartin-associated, C-terminal [IPR009686]", "Sentrin-specific protease 3/5, conserved domain [IPR045577]", "Septin-type guanine nucleotide-binding (G) domain [IPR030379]", "Serine aminopeptidase, S33 [IPR022742]", "Serine hydroxymethyltransferase-like domain [IPR039429]", "Serine-tRNA ligase catalytic core domain [IPR033729]", "Serine-tRNA synthetase, type1, N-terminal [IPR015866]", "Serine-threonine protein phosphatase, N-terminal [IPR031675]", "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "Serine/arginine-rich splicing factor SRSF4-like, RNA recognition motif 1 [IPR035585]", "Serine/threonine-protein PRP4, catalytic domain [IPR044092]", "Serine/threonine-protein kinase MRCK beta, catalytic domain [IPR042718]", "Serine/threonine-protein kinase N, C2 domain [IPR037784]", "Serine/threonine-protein kinase N, first HR1 domain [IPR037313]", "Serine/threonine-protein kinase N1, second HR1 domain [IPR037317]", "Serine/threonine-protein kinase Nek9, catalytic domain [IPR042767]", "Serine/threonine-protein kinase OSR1/WNK, CCT domain [IPR024678]", "Serine/threonine-protein kinase Rio2 [IPR030484]", "Serine/threonine-protein kinase SMG1, N-terminal [IPR035175]", "Serine/threonine-protein kinase greatwall, catalytic domain [IPR037638]", "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "Serpin H1, serpin domain [IPR033830]", "Serpin domain [IPR023796]", "Set1A, RNA recognition motif [IPR034467]", "Siah interacting protein, N-terminal [IPR015120]", "Signal recognition particle SRP54, helical bundle [IPR013822]", "Signal recognition particle receptor, alpha subunit, N-terminal [IPR007222]", "Signal recognition particle subunit SRP68, RNA-binding domain [IPR034652]", "Signal recognition particle, SRP54 subunit, GTPase domain [IPR000897]", "Signal recognition particle, SRP54 subunit, M-domain [IPR004125]", "Signal recognition particle, SRP72 subunit, RNA-binding [IPR013699]", "Signal transducer and activation of transcription 1, TAZ2 binding domain, C-terminal [IPR022752]", "Signal transduction histidine kinase-related protein, C-terminal [IPR004358]", "Sin3, C-terminal [IPR031693]", "Sirtuin family, catalytic core domain [IPR026590]", "Sister chromatid cohesion C-terminal domain [IPR024986]", "Ski2, N-terminal domain [IPR040801]", "Sm-like protein LSm5 [IPR033871]", "Sm-like protein Lsm3 [IPR034105]", "Sm-like protein Lsm8 [IPR034103]", "Small G protein signalling modulator 1/2, Rab-binding domain [IPR021935]", "Small GTP-binding protein domain [IPR005225]", "Small acidic protein-like domain [IPR028124]", "Small nuclear ribonucleoprotein D1 [IPR034102]", "Small-subunit processome, Utp12 [IPR007148]", "Small-subunit processome, Utp13 [IPR013934]", "Small-subunit processome, Utp21 [IPR007319]", "Smc1, ATP-binding cassette domain [IPR028468]", "Smc2, ATP-binding cassette domain [IPR027120]", "Snf2, ATP coupling domain [IPR029295]", "Snu114, GTP-binding domain [IPR044121]", "SoHo domain [IPR003127]", "Sof1-like protein [IPR007287]", "Solute carrier family 3 member 2, N-terminal domain [IPR031984]", "Sortilin, C-terminal [IPR031777]", "Sortilin, N-terminal [IPR031778]", "Sorting Nexin 1, PX domain [IPR034901]", "Sorting nexin 4, PX domain [IPR034902]", "Sorting nexin 8/Mvp1, BAR domain [IPR045734]", "Sorting nexin Vps5-like, C-terminal [IPR015404]", "Sorting nexin protein, WASP-binding domain [IPR019497]", "Sorting nexin, N-terminal [IPR005329]", "Sorting nexin-17/31, FERM domain [IPR040842]", "Sorting nexin-4, BAR domain [IPR037430]", "Sorting nexin-9, BAR domain [IPR037425]", "Sorting nexin-9, PX domain [IPR037426]", "Spen paralogue and orthologue SPOC, C-terminal [IPR012921]", "Spen paralogue/orthologue C-terminal, metazoa [IPR010912]", "Spermidine synthase, tetramerisation domain [IPR035246]", "Spermine synthase, N-terminal [IPR040900]", "Splicing factor 1, helix-hairpin domain [IPR032570]", "Splicing factor 3A subunit 1, conserved domain [IPR022030]", "Splicing factor 3A subunit 1, ubiquitin domain [IPR035563]", "Splicing factor 3B subunit 1 [IPR015016]", "Splicing factor ELAV/Hu, RNA recognition motif 1 [IPR034775]", "Splicing factor RBM39, linker [IPR029123]", "Splicing factor SF3a60 /Prp9 subunit, C-terminal [IPR024598]", "Splicing factor SF3a60 binding domain [IPR021966]", "Spp2/MOS2, G-patch domain [IPR026822]", "Spt5 C-terminal domain [IPR024945]", "Spt5 transcription elongation factor, N-terminal [IPR022581]", "Spt5, KOW domain repeat 1 [IPR041973]", "Spt5, KOW domain repeat 2 [IPR041975]", "Spt5, KOW domain repeat 3 [IPR041976]", "Spt5, KOW domain repeat 4 [IPR041977]", "Spt5, KOW domain repeat 5 [IPR041978]", "Spt5, KOW domain repeat 6 [IPR041980]", "Spt6 acidic, N-terminal domain [IPR028083]", "Spt6, SH2 domain [IPR035420]", "Spt6, SH2 domain, C terminus [IPR035018]", "Spt6, SH2 domain, N terminus [IPR035019]", "Squalene cyclase, C-terminal [IPR032696]", "Squalene cyclase, N-terminal [IPR032697]", "Squalene epoxidase [IPR013698]", "Srp40, C-terminal [IPR007718]", "StAR-related lipid transfer protein 3, C-terminal [IPR029867]", "Staphylococcal nuclease (SNase-like), OB-fold [IPR016071]", "Staufen 1, third double-stranded RNA binding domain [IPR044475]", "Staufen, C-terminal [IPR032478]", "Steadiness box (SB) domain [IPR017916]", "Sterile alpha motif domain [IPR001660]", "Sterol-sensing domain [IPR000731]", "Striatin, N-terminal [IPR013258]", "Strictosidine synthase, conserved region [IPR018119]", "Stromalin conservative domain [IPR020839]", "Structural maintenance of chromosomes 3, ABC domain, eukaryotic [IPR041741]", "Structural maintenance of chromosomes 4, ABC domain, eukaryotic [IPR041738]", "Succinate dehydogenase/fumarate reductase N-terminal [IPR025192]", "Sulfatase, N-terminal [IPR000917]", "Sulfatase-modifying factor enzyme [IPR005532]", "Sulfhydryl oxidase, Trx-like domain [IPR041269]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain [IPR040986]", "Sulfotransferase domain [IPR000863]", "Sulphate adenylyltransferase [IPR002650]", "Sulphate adenylyltransferase catalytic domain [IPR024951]", "Suppressor of forked [IPR008847]", "Suppressor of white apricot, N-terminal domain [IPR019147]", "Survival motor neuron [IPR010304]", "Suv3, C-terminal domain 1 [IPR041082]", "Suv3, DEXQ-box helicase domain [IPR044774]", "Suv3, N-terminal [IPR041453]", "Symplekin C-terminal [IPR022075]", "Symplekin/Pta1, N-terminal [IPR032460]", "Synaptic functional regulator FMRP, KH0 domain [IPR040472]", "Synaptotagmin, SMP domain [IPR039010]", "Synaptotagmin-like mitochondrial-lipid-binding domain [IPR031468]", "Synaptotagmin-like, mitochondrial and lipid-binding domain [IPR040885]", "Syndetin, C-terminal [IPR019514]", "Synembryn [IPR008376]", "Syntaxin 6, N-terminal [IPR015260]", "Syntaxin, N-terminal domain [IPR006011]", "Syntaxin-5, N-terminal, Sly1p-binding domain [IPR021538]", "Syntaxin-8, SNARE domain [IPR041875]", "TAP C-terminal (TAP-C) domain [IPR005637]", "TAR DNA-binding protein 43, N-terminal [IPR041105]", "TATA box binding protein associated factor (TAF) [IPR004823]", "TATA element modulatory factor 1, TATA binding [IPR022091]", "TATA-binding protein interacting (TIP20) [IPR013932]", "TBCE, ubiquitin-like (Ubl) domain [IPR044079]", "TCB1D9/TCB1D9B, PH-GRAM domain 1 [IPR036014]", "TCB1D9/TCB1D9B, PH-GRAM domain 2 [IPR036017]", "TFG box [IPR025768]", "TFG, PB1 domain [IPR034857]", "TFIIEalpha/SarR/Rpc3 HTH domain [IPR024550]", "TFIIF beta subunit, HTH domain [IPR040450]", "TFIIF, beta subunit, N-terminal [IPR040504]", "TFIIH p62 subunit, N-terminal [IPR013876]", "TGS [IPR004095]", "THADA/TRM732, DUF2428 [IPR019442]", "THAP-type zinc finger [IPR006612]", "THIF-type NAD/FAD binding fold [IPR000594]", "THO complex subunit 2, N-terminal domain [IPR032302]", "THO complex, subunitTHOC2, C-terminal [IPR021418]", "THO complex, subunitTHOC2, N-terminal [IPR021726]", "THUMP domain [IPR004114]", "TIAR, RNA recognition motif 1 [IPR034492]", "TIAR, RNA recognition motif 2 [IPR034494]", "TIAR, RNA recognition motif 3 [IPR034496]", "TIF1-beta, RING finger, HC subclass [IPR042713]", "TIP49, P-loop domain [IPR010339]", "TOG domain [IPR034085]", "TOPK, catalytic domain [IPR041989]", "TOPRIM domain [IPR006171]", "TPX2 central domain [IPR027330]", "TPX2, C-terminal [IPR027329]", "TRAM domain [IPR002792]", "TRAM/LAG1/CLN8 homology domain [IPR006634]", "TRAM1-like protein [IPR013599]", "TRASH domain [IPR011017]", "TRF2-interacting telomeric protein/Rap1, C-terminal [IPR021661]", "TRIAD supradomain [IPR044066]", "TRIM21, PRY/SPRY domain [IPR035831]", "TRIM25, PRY/SPRY domain [IPR042753]", "TRIM27, PRY/SPRY domain [IPR035791]", "TRMT2A, RNA recognition motif [IPR034262]", "TROVE domain [IPR008858]", "TUG ubiquitin-like domain [IPR021569]", "TUTase nucleotidyltransferase domain [IPR045100]", "Talin, N-terminal F0 domain [IPR032425]", "Talin, central [IPR015224]", "Talin-1/2, rod-segment [IPR037438]", "Tankyrase 1-binding protein, C-terminal [IPR032764]", "Target SNARE coiled-coil homology domain [IPR000727]", "TatSF1-like, RNA recognition motif 1 [IPR034392]", "Tectonic domain [IPR011677]", "Telomere length regulation protein, conserved domain [IPR019337]", "Telomere-associated protein Rif1, N-terminal [IPR022031]", "Tensin phosphatase, C2 domain [IPR014020]", "Tensin-type phosphatase domain [IPR029023]", "Tesmin/TSO1-like CXC domain [IPR033467]", "Testin, LIM domain 1 [IPR034958]", "Testin, LIM domain 2 [IPR034959]", "Testin, LIM domain 3 [IPR034960]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain [IPR020631]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain [IPR020630]", "Tetrapyrrole methylase [IPR000878]", "Tetratricopeptide repeat protein 7, N-terminal [IPR045819]", "Tetratricopeptide repeat-like domain [IPR018704]", "Tetratricopeptide, SHNi-TPR domain [IPR019544]", "Tfc3, extended winged-helix domain [IPR035625]", "Thiamine pyrophosphate enzyme, C-terminal TPP-binding [IPR011766]", "Thiamine pyrophosphate enzyme, N-terminal TPP-binding domain [IPR012001]", "Thiamine pyrophosphate enzyme, central domain [IPR012000]", "Thioesterase [IPR001031]", "Thioesterase domain [IPR006683]", "Thiolase, C-terminal [IPR020617]", "Thiolase, N-terminal [IPR020616]", "Thioredoxin domain [IPR013766]", "Thioredoxin domain-containing protein 17-like domain [IPR010357]", "Thioredoxin-like fold [IPR012336]", "Thioredoxin-related transmembrane protein 2, thioredoxin domain [IPR037463]", "Threonine-tRNA ligase catalytic core domain [IPR033728]", "Threonyl/alanyl tRNA synthetase, SAD [IPR012947]", "Thymidylate kinase-like domain [IPR039430]", "Thymidylate synthase/dCMP hydroxymethylase domain [IPR023451]", "Tim10-like [IPR004217]", "Tim44-like domain [IPR007379]", "Timeless, C-terminal [IPR007725]", "Timeless, N-terminal [IPR006906]", "Toll-interacting protein, C2 domain [IPR037301]", "Toll-interacting protein, CUE domain [IPR041799]", "Toll/interleukin-1 receptor homology (TIR) domain [IPR000157]", "Topoisomerase I C-terminal domain [IPR025834]", "Trafficking protein particle complex subunit 11 [IPR021773]", "Trafficking protein particle complex subunit 11, C-terminal [IPR025876]", "Trans-isoprenyl diphosphate synthases, head-to-head [IPR033904]", "Transcription elongation factor S-II, central domain [IPR003618]", "Transcription elongation factor Spt6, YqgF domain [IPR028231]", "Transcription elongation factor Spt6, helix-hairpin-helix motif [IPR032706]", "Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type [IPR003617]", "Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]", "Transcription factor CP2, SAM domain [IPR037599]", "Transcription factor IIIC subunit 5, HTH domain [IPR019136]", "Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain [IPR041499]", "Transcription factor IIIC, 90kDa subunit, N-terminal [IPR024761]", "Transcription factor IIIC, putative zinc-finger [IPR024764]", "Transcription factor IIS, N-terminal [IPR017923]", "Transcription factor TFE/TFIIEalpha HTH domain [IPR017919]", "Transcription factor TFIIB, cyclin-like domain [IPR013150]", "Transcription factor TFIIE alpha subunit, C-terminal [IPR021600]", "Transcription factor Tfb2, C-terminal domain [IPR040662]", "Transcription initiation factor IIE subunit alpha, N-terminal [IPR002853]", "Transcription termination and cleavage factor, C-terminal domain [IPR026896]", "Transcriptional coactivator p15 (PC4), C-terminal [IPR003173]", "Transcriptional repressor p66, coiled-coil MBD2-interaction domain [IPR032346]", "Transferrin receptor protein 1/2, PA domain [IPR037324]", "Transferrin receptor-like, dimerisation domain [IPR007365]", "Transforming acidic coiled-coil-containing protein, C-terminal [IPR007707]", "Transketolase, C-terminal domain [IPR033248]", "Transketolase, N-terminal [IPR005474]", "Transketolase-like, pyrimidine-binding domain [IPR005475]", "Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]", "Translation elongation factor EFG/EF2, domain IV [IPR005517]", "Translation elongation factor EFTs/EF1B, dimerisation [IPR014039]", "Translation elongation factor EFTu-like, domain 2 [IPR004161]", "Translation elongation factor EFTu/EF1A, C-terminal [IPR004160]", "Translation elongation factor, IF5A C-terminal [IPR020189]", "Translation initiation factor IF- 2, domain 3 [IPR023115]", "Translation initiation factor IF-2, domain II [IPR044145]", "Translation initiation factor IF2/IF5 domain [IPR002735]", "Translation initiation factor eIF-2B subunit epsilon, N-terminal [IPR035543]", "Translation initiation factor eIF-2B subunit epsilon, W2 domain [IPR044123]", "Translation initiation factor, beta propellor-like domain [IPR013979]", "Translational (tr)-type GTP-binding domain [IPR000795]", "Translationally controlled tumour protein (TCTP) domain [IPR034737]", "Translocon Sec61/SecY, plug domain [IPR019561]", "Transmembrane protein 131-like, N-terminal [IPR022113]", "Transmembrane protein 131-like, conserved domain [IPR045695]", "Transmembrane protein 201, C-terminal [IPR018861]", "Treacle protein domain [IPR003993]", "Tripartite DENN domain [IPR037516]", "Tripeptidyl-peptidase II domain [IPR034051]", "TrmE-type guanine nucleotide-binding domain [IPR031168]", "TryX and NRX, thioredoxin domain [IPR045870]", "Tubulin epsilon and delta complex protein 1 domain [IPR027996]", "Tubulin-folding cofactor B, N-terminal ubiquitin-like domain [IPR045172]", "Tubulin-specific chaperone D, C-terminal [IPR022577]", "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "Tubulin/FtsZ, GTPase domain [IPR003008]", "Tudor domain [IPR002999]", "Tuftelin interacting protein, N-terminal domain [IPR022159]", "Tumour suppressor p53-binding protein-1 Tudor domain [IPR015125]", "Tyrosine-protein kinase BAZ1B, bromodomain [IPR037375]", "Tyrosine-protein kinase ephrin type A/B receptor-like [IPR011641]", "Tyrosine-protein kinase, catalytic domain [IPR020635]", "Tyrosine-specific protein phosphatase, PTPase domain [IPR000242]", "Tyrosine-specific protein phosphatases domain [IPR000387]", "U-box domain [IPR003613]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 1 [IPR034407]", "U1 small nuclear ribonucleoprotein A, RNA recognition motif 2 [IPR034409]", "U1 small nuclear ribonucleoprotein of 70kDa N-terminal [IPR022023]", "U1-C, C2H2-type zinc finger [IPR013085]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 2 [IPR034562]", "U2 small nuclear ribonucleoprotein B'', RNA recognition motif 1 [IPR034564]", "U2A'/phosphoprotein 32 family A, C-terminal [IPR003603]", "U3 small nucleolar RNA-associated protein 10, N-terminal [IPR022125]", "U3 small nucleolar RNA-associated protein 15, C-terminal [IPR018983]", "UAS [IPR006577]", "UBAC1, UBA domain 1 [IPR041926]", "UBAC1, UBA domain 2 [IPR041927]", "UBAC2, UBA domain [IPR041928]", "UBX domain [IPR001012]", "UBXN1, UBA domain [IPR041923]", "UBXN6, PUB domain [IPR042774]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal [IPR014027]", "UDP-glucose/GDP-mannose dehydrogenase, N-terminal [IPR001732]", "UDP-glucose/GDP-mannose dehydrogenase, dimerisation [IPR014026]", "UDP-glucose:glycoprotein glucosyltransferase, thioredoxin-like domain 4 [IPR040525]", "UDP-glucuronate decarboxylase N-terminal [IPR021761]", "UDP-glycosyltransferase family, conserved site [IPR035595]", "UGGT, thioredoxin-like domain 1 [IPR040693]", "UGGT, thioredoxin-like domain 2 [IPR040694]", "UGGT, thioredoxin-like domain 3 [IPR040692]", "UHRF1, tandem tudor domain [IPR021991]", "UNC-45/Cro1/She4, central domain [IPR024660]", "UPF0113, PUA domain [IPR005155]", "UPF0113, pre-PUA domain [IPR040598]", "UPF3 domain [IPR005120]", "UPF3B, RNA recognition motif-like domain [IPR034979]", "USP8 dimerisation domain [IPR015063]", "UVR domain [IPR001943]", "Ubiquinol-cytochrome c reductase 8kDa, N-terminal [IPR015248]", "Ubiquinol-cytochrome c reductase, iron-sulphur subunit [IPR006317]", "Ubiquitin E2 variant, N-terminal [IPR008883]", "Ubiquitin carboxyl-terminal hydrolase 47, C-terminal [IPR045578]", "Ubiquitin carboxyl-terminal hydrolase 5, UBA1 domain [IPR041812]", "Ubiquitin carboxyl-terminal hydrolase 7, ICP0-binding domain [IPR024729]", "Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]", "Ubiquitin conjugation factor E4, core [IPR019474]", "Ubiquitin specific peptidase 1 [IPR033815]", "Ubiquitin specific protease domain [IPR028889]", "Ubiquitin system component CUE [IPR003892]", "Ubiquitin-activating enzyme E1, C-terminal [IPR018965]", "Ubiquitin-activating enzyme E1, FCCH domain [IPR032418]", "Ubiquitin-activating enzyme E1, four-helix bundle [IPR032420]", "Ubiquitin-activating enzyme, SCCH domain [IPR019572]", "Ubiquitin-associated domain [IPR015940]", "Ubiquitin-conjugating enzyme E2 [IPR000608]", "Ubiquitin-like domain [IPR000626]", "Ubiquitin-like domain, USP-type [IPR028135]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal [IPR032197]", "Ubiquitin-specific peptidase 38 [IPR033840]", "Ubiquitin-specific peptidase 48 [IPR033841]", "Ubiquitin-specific-processing protease 48, Ubl domain [IPR044743]", "Ubiquitin/SUMO-activating enzyme ubiquitin-like domain [IPR028077]", "Ubiquitinyl hydrolase, variant UBP zinc finger [IPR041432]", "Ubiquitinyl hydrolase-L5 [IPR033837]", "Ulp1 protease family, C-terminal catalytic domain [IPR003653]", "Uncharacterised domain CHP00451 [IPR004521]", "Uncharacterised domain NUC130/133, N-terminal [IPR012977]", "Uncharacterised domain NUC173 [IPR012978]", "Uncharacterised domain NUC202 [IPR012980]", "Up-frameshift suppressor 2, C-terminal [IPR007193]", "Uracil-DNA glycosylase-like [IPR005122]", "Uroporphyrinogen decarboxylase (URO-D) [IPR000257]", "Uso1/p115-like vesicle tethering protein, C-terminal [IPR006955]", "VASP tetramerisation [IPR014885]", "VHS domain [IPR002014]", "VIP36, lectin domain [IPR035664]", "VPS10 [IPR006581]", "VPS13, repeated coiled region [IPR031642]", "VPS9 domain [IPR003123]", "Vacuolar protein sorting protein 36, GLUE domain [IPR021648]", "Vacuolar protein sorting-associated protein 13, C-terminal [IPR031645]", "Vacuolar protein sorting-associated protein 13, SHR-binding domain [IPR009543]", "Vacuolar protein sorting-associated protein 13, second N-terminal domain [IPR031646]", "Vacuolar protein sorting-associated protein 13-like, N-terminal domain [IPR026854]", "Vacuolar protein sorting-associated protein 13D, UBA domain [IPR041969]", "Vacuolar protein sorting-associated protein 4, MIT domain [IPR045253]", "Vacuolar protein sorting-associated protein 54, N-terminal [IPR019515]", "Vacuolar protein sorting-associated, VPS28, C-terminal [IPR017899]", "Vacuolar protein sorting-associated, VPS28, N-terminal [IPR017898]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 1 [IPR019452]", "Vacuolar sorting protein 39/Transforming growth factor beta receptor-associated domain 2 [IPR019453]", "Valyl tRNA synthetase, anticodon-binding domain [IPR033705]", "Vertebrate SNX3, PX domain [IPR042137]", "Vertebrate ubiquitin-conjugating enzyme E2 K, UBA domain [IPR042599]", "Vesicle tethering protein Uso1/P115-like , head domain [IPR006953]", "Vicinal oxygen chelate (VOC) domain [IPR037523]", "Vinculin-binding site-containing domain [IPR015009]", "Vinexin, SH3 domain 1 [IPR035609]", "Vinexin, SH3 domain 2 [IPR035608]", "Vinexin, SH3 domain 3 [IPR035607]", "Virilizer, N-terminal [IPR031801]", "Vitamin B12-dependent methionine synthase, activation domain [IPR004223]", "Vitamin K epoxide reductase [IPR012932]", "Vps16, C-terminal [IPR006925]", "Vps16, N-terminal [IPR006926]", "Vps4 oligomerisation, C-terminal [IPR015415]", "Vps53-like, N-terminal [IPR007234]", "Vps72/YL1, C-terminal [IPR013272]", "Vta1, C-terminal [IPR041212]", "Vta1/callose synthase, N-terminal [IPR039431]", "W2 domain [IPR003307]", "WAPL domain [IPR012502]", "WASH complex subunit 4, N-terminal [IPR028191]", "WASH complex subunit 7, C-terminal [IPR028283]", "WASH complex subunit 7, central domain [IPR028282]", "WD repeat-containing protein 18, C-terminal domain [IPR026987]", "WGR domain [IPR008893]", "WH1/EVH1 domain [IPR000697]", "WH2 domain [IPR003124]", "WHEP-TRS domain [IPR000738]", "WHIM1 domain [IPR028942]", "WHIM2 domain [IPR028941]", "WSTF/Acf1/Cbp146 [IPR013136]", "WW domain [IPR001202]", "WWE domain [IPR004170]", "Wings apart-like protein, C-terminal [IPR022771]", "Wolframin, EF-hand domain [IPR045460]", "Wolframin, OB-fold domain [IPR045461]", "Wolframin, cysteine-rich domain [IPR045400]", "XPC-binding domain [IPR015360]", "XPG, N-terminal [IPR006085]", "XPG-I domain [IPR006086]", "XRCC1, first (central) BRCT domain [IPR045080]", "XRN2-binding (XTBD) domain [IPR021859]", "Xrn1, helical domain [IPR041412]", "YKT6, SNARE motif [IPR045848]", "YTH domain [IPR007275]", "YchF, C-terminal domain [IPR013029]", "YchF, N-terminal [IPR041706]", "YegS/DAGK, C-terminal domain [IPR045540]", "Yip1 domain [IPR006977]", "YjeF N-terminal domain [IPR004443]", "YqgF/RNase H-like domain [IPR006641]", "Z-binding domain [IPR042371]", "ZAP, helix turn helix N-terminal domain [IPR041360]", "ZAP, zinc finger [IPR040954]", "ZC3H15/TMA46 family, C-terminal [IPR032378]", "ZCRB1, RNA recognition motif [IPR034219]", "ZMYND8/11, PWWP domain [IPR035505]", "ZN598/Hel2, RING finger [IPR041888]", "ZN622/Rei1/Reh1, zinc finger C2H2-type [IPR041661]", "ZO-1, SH3 domain [IPR035597]", "ZO-2, SH3 domain [IPR035598]", "ZU5 domain [IPR000906]", "Zasp-like motif [IPR006643]", "Zinc finger C2H2 AKAP95-type [IPR034736]", "Zinc finger C2H2-type [IPR013087]", "Zinc finger, A20-type [IPR002653]", "Zinc finger, AN1-type [IPR000058]", "Zinc finger, B-box, chordata [IPR020457]", "Zinc finger, C2H2, LYAR-type [IPR014898]", "Zinc finger, C2HC5-type [IPR009349]", "Zinc finger, C3HC-like [IPR012935]", "Zinc finger, C3HC4 RING-type [IPR018957]", "Zinc finger, CCCH-type [IPR000571]", "Zinc finger, CCHC-type [IPR001878]", "Zinc finger, CHCC-type [IPR019401]", "Zinc finger, CHHC-type [IPR012996]", "Zinc finger, CW-type [IPR011124]", "Zinc finger, CXXC-type [IPR002857]", "Zinc finger, ClpX C4-type [IPR010603]", "Zinc finger, DNA-directed DNA polymerase, family B, alpha [IPR015088]", "Zinc finger, FPG/IleRS-type [IPR010663]", "Zinc finger, FYVE-related [IPR017455]", "Zinc finger, GATA-type [IPR000679]", "Zinc finger, GRF-type [IPR010666]", "Zinc finger, HIT-type [IPR007529]", "Zinc finger, LIM-type [IPR001781]", "Zinc finger, MIZ-type [IPR004181]", "Zinc finger, MYM-type [IPR010507]", "Zinc finger, MYND-type [IPR002893]", "Zinc finger, PARP-type [IPR001510]", "Zinc finger, PHD-finger [IPR019787]", "Zinc finger, PHD-type [IPR001965]", "Zinc finger, RING-CH-type [IPR011016]", "Zinc finger, RING-type [IPR001841]", "Zinc finger, RanBP2-type [IPR001876]", "Zinc finger, Sec23/Sec24-type [IPR006895]", "Zinc finger, TFIIB-type [IPR013137]", "Zinc finger, TFIIS-type [IPR001222]", "Zinc finger, UBP-type [IPR001607]", "Zinc finger, UBR-type [IPR003126]", "Zinc finger, ZPR1-type [IPR004457]", "Zinc finger, ZZ-type [IPR000433]", "Zinc finger, double-stranded RNA binding [IPR022755]", "Zinc knuckle CX2CX3GHX4C [IPR025829]", "Zinc ribbon, NADH pyrophosphatase [IPR015376]", "Zinc-finger C2H2-type 11 [IPR041697]", "Zinc-finger CCCH domain [IPR041686]", "Zn-dependent metallo-hydrolase, RNA specificity domain [IPR011108]", "bMERB domain [IPR022735]", "cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]", "cDENN domain [IPR001194]", "cGMP-dependent protein kinase, interacting domain [IPR031775]", "dDENN domain [IPR005112]", "dUTPase, trimeric [IPR033704]", "dUTPase-like [IPR029054]", "eIF3 subunit M, C-terminal helix domain [IPR040750]", "eIF3B, RNA recognition motif [IPR034363]", "eIF3G, RNA recognition motif [IPR034240]", "eIF3h, C-terminal [IPR045810]", "eIF4H, RNA recognition motif [IPR034229]", "eRF1 domain 1/Pelota-like [IPR005140]", "eRF1 domain 2 [IPR005141]", "eRF1 domain 3 [IPR005142]", "hnRNP A0, RNA recognition motif 1 [IPR034801]", "hnRNP A1, RNA recognition motif 1 [IPR034845]", "hnRNP A1, RNA recognition motif 2 [IPR034803]", "hnRNP A2/B1, RNA recognition motif 1 [IPR034486]", "hnRNP A3, RNA recognition motif 1 [IPR034513]", "hnRNP A3, RNA recognition motif 2 [IPR034516]", "hnRNP DL, RNA recognition motif 1 [IPR034847]", "hnRNP-L, RNA recognition motif 1 [IPR035005]", "hnRNP-L, RNA recognition motif 2 [IPR035008]", "hnRNP-L, RNA recognition motif 3 [IPR034816]", "hnRNP-L, RNA recognition motif 4 [IPR034817]", "hnRNPAB, RNA recognition motif 1 [IPR034846]", "hnRNPH3, RNA recognition motif 2 [IPR034970]", "hnRNPH3, RNA recognition motif 3 [IPR034969]", "hnRNPM, RNA recognition motif 3 [IPR034990]", "mRNA (guanine-N(7))-methyltransferase domain [IPR004971]", "mRNA capping enzyme, C-terminal [IPR013846]", "mRNA capping enzyme, adenylation domain [IPR001339]", "mRNA decay factor PAT1 domain [IPR019167]", "mRNA splicing factor Cwf21 domain [IPR013170]", "mRNA-decapping enzyme, C-terminal [IPR031953]", "p115RhoGEF, RGS domain [IPR037887]", "p21 activated kinase binding domain [IPR033923]", "p21-activated kinase 2, catalytic domain [IPR035064]", "p53 transactivation domain [IPR013872]", "p53, DNA-binding domain [IPR011615]", "p53, tetramerisation domain [IPR010991]", "p54nrb, RNA recognition motif 1 [IPR034552]", "rRNA-processing arch domain [IPR025696]", "snRNP70, RNA recognition motif [IPR034143]", "tRNA methyltransferase TRM10-type domain [IPR028564]", "tRNA methyltransferase TRMD/TRM10-type domain [IPR016009]", "tRNA pseudouridylate synthase B, C-terminal [IPR032819]", "tRNA synthetase, B5-domain [IPR005147]", "tRNA synthetases class I, catalytic domain [IPR032678]", "tRNA(Met) cytidine acetyltransferase TmcA, N-terminal [IPR013562]", "tRNA-binding domain [IPR002547]", "tRNA-guanine(15) transglycosylase-like [IPR002616]", "tRNA/rRNA methyltransferase, SpoU type [IPR001537]", "tRNase Z endonuclease [IPR027794]", "uDENN domain [IPR005113]", "v-SNARE, coiled-coil homology domain [IPR042855]", "von Willebrand factor, type A [IPR002035]"], "available_proteins": ["AAK1", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADRM1", "ADSL", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "APLP2", "APMAP", "APOBEC3C", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC10", "ARMCX3", "ARMT1", "ARRB2", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "ATP6V1H", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GALT1", "B4GALT3", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAP18", "BAZ1A", "BAZ1B", "BAZ2A", "BCAP31", "BCAS3", "BCKDK", "BCR", "BCS1L", "BECN1", "BEND3", "BIRC6", "BLM", "BLVRA", "BMS1", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C10orf76", "C1orf198", "C1orf35", "C2CD2", "C2CD2L", "C2CD5", "C3orf58", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALM3", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CARM1", "CARS", "CASK", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC93", "CCDC97", "CD109", "CD2AP", "CD2BP2", "CD47", "CDC20", "CDC23", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPH", "CENPV", "CEP170", "CEP290", "CEP44", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHORDC1", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN6", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPB", "CLPX", "CLSTN3", "CLTC", "CLU", "CLUH", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT3", "CNOT4", "CNPY2", "COA3", "COASY", "COIL", "COLEC12", "COMMD2", "COMMD6", "COMMD8", "COPA", "COPB1", "COPB2", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX2", "COX6C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CROT", "CRYZ", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNBL1", "CTPS1", "CTPS2", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC22", "CWC27", "CWF19L1", "CXADR", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "DAGLB", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCK", "DCP1A", "DCP1B", "DCTN1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DDA1", "DDB1", "DDI2", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC2H1", "EARS2", "ECE1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B3", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "EMC1", "EMC7", "EMC8", "EMD", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERLIN1", "ERLIN2", "ERMP1", "ERP29", "ERP44", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC4", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM129B", "FAM160B2", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDXR", "FECH", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNBP1", "FNBP4", "FNDC3A", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GAK", "GAL", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLM", "GCN1", "GDAP2", "GDE1", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GHITM", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGB1", "GOPC", "GORASP2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH11", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPRASP2", "GPS1", "GPT2", "GRB2", "GRHPR", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF3C1", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS3", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDLBP", "HEATR1", "HEATR6", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HMBS", "HMG20A", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMMR", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HS1BP3", "HSD17B4", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA4", "HSPA4L", "HSPBP1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "IAH1", "IARS", "IARS2", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPACT", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "ISOC2", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAM3", "JMJD6", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1147", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KNOP1", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMTOR2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC47", "LRRC8A", "LRRC8C", "LRSAM1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYRM2", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAEA", "MAGED2", "MAK16", "MAN2A1", "MAN2B1", "MANF", "MAP2K1", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAVS", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED25", "MEPCE", "METAP1", "METAP2", "METTL13", "METTL7B", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD8", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMS19", "MOCOS", "MOCS1", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRM3", "MRPL11", "MRPL12", "MRPL15", "MRPL16", "MRPL2", "MRPL24", "MRPL39", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL48", "MRPL58", "MRPL9", "MRPS23", "MRPS25", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTF2", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA40", "NAA50", "NADSYN1", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCBP1", "NCEH1", "NCK1", "NCKIPSD", "NCL", "NCLN", "NCSTN", "ND5", "NDE1", "NDUFA10", "NDUFA2", "NDUFA6", "NDUFA9", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NTHL1", "NTPCR", "NUB1", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP50", "NUP54", "NUP62", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OBSL1", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAX6", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCM1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDXK", "PDZD11", "PDZD8", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX6", "PFAS", "PFKL", "PFKM", "PFKP", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PICALM", "PIGG", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PITHD1", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLAA", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "POP1", "POR", "PPAN", "PPAT", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPWD1", "PQBP1", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRELID3B", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSPC1", "PTBP1", "PTCD1", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUF60", "PUM3", "PUS1", "PUS7", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "PYCR3", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "R3HCC1", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RAC1", "RACGAP1", "RAD21", "RAD23B", "RAD50", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDX", "RECQL", "REPS1", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIF1", "RIOK2", "RIOX2", "RIPK1", "RMI1", "RMND1", "RNASEH2A", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL11", "RPL12", "RPL14", "RPL18", "RPL18A", "RPL19", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL30", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPP25L", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS2", "RPS20", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRP12", "RRP7A", "RSF1", "RSL24D1", "RTCA", "RTF1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAMM50", "SAP30", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SC5D", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCLY", "SCML2", "SCO2", "SCP2", "SCRIB", "SCYL1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC25A12", "SLC25A13", "SLC25A24", "SLC25A25", "SLC27A4", "SLC2A1", "SLC38A2", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMN1*", "SMNDC1", "SMS", "SMU1", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STRIP1", "STRN", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TAF15", "TAGLN2", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCTN3", "TDRKH", "TECR", "TEDC1", "TELO2", "TERF2IP", "TES", "TEX10", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THAP11", "THOC1", "THOC2", "THOC3", "THOP1", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIMELESS", "TIMM10B", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM131", "TMEM201", "TMEM205", "TMEM97", "TMF1", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOP1", "TOP2A", "TOP2B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSR1", "TSTA3", "TTC4", "TTC7B", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBL5", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UCK2", "UGDH", "UGGT1", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRC1", "UQCRC2", "UQCRFS1", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP20", "UTRN", "UXS1", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VCP", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13A", "VPS13D", "VPS16", "VPS18", "VPS28", "VPS29", "VPS36", "VPS37B", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "VWA8", "WAPL", "WARS", "WASF2", "WASHC4", "WBP2", "WDHD1", "WDR12", "WDR18", "WDR3", "WDR36", "WDR43", "WDR46", "WFS1", "WIZ", "WNK1", "WRN", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YBX1", "YIPF4", "YKT6", "YME1L1", "YTHDC1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZDHHC13", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM1", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF644", "ZNF687", "ZNHIT2", "ZPR1", "ZYX"], "leading_proteins": ["ABCB7", "ABI1", "ACOT9", "ACTN1", "ACTN4", "ADD3", "AFG3L2", "AKT2", "ALCAM", "ALDH1B1", "ANAPC2", "ANKLE2", "AP1B1", "AP3B1", "APBB1", "APP", "ARHGAP1", "ARID1A", "ARID2", "ARIH1", "ATAD3B", "ATL2", "ATP2A2", "ATP2B1", "B4GALT3", "BAIAP2", "BAZ1A", "BAZ1B", "BAZ2A", "BCKDK", "BCR", "BMS1", "BSG", "CADM1", "CAPN5", "CASK", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CDC42BPB", "CDH2", "CDK5RAP1", "CERS1", "CERS2", "CHD1", "CHD4", "CHD7", "CHUK", "CIZ1", "CLSTN3", "COPS2", "COPS3", "COPS4", "COPS7B", "CPSF3", "CSK", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5D2", "CYFIP2", "DCTN1", "DHCR24", "DIAPH1", "DIAPH3", "DICER1", "DNAJA2", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNM3", "DOCK1", "DRG2", "DYNC2H1", "EARS2", "EEF1A2", "EEF1D", "EEF2", "EFCAB14", 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0000000000000000000000000000000000000000..9fac97e6154138783f939dc931f0fc8139f6a2cd --- /dev/null +++ b/interpro_family/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Proteasome B-type subunit [IPR023333]", "1": "Proteasome, subunit alpha/beta [IPR001353]"} \ No newline at end of file diff --git a/interpro_family/basic/plot_0.png b/interpro_family/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..3d9bf97bedcdde9de0126ce744c9f4adec8582f1 --- /dev/null +++ b/interpro_family/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:d2e4c1a02b10d7b0681808457def2bcbda04b632a82897f0868c5d37255d8b1b +size 138998 diff --git a/interpro_family/basic/plot_1.png b/interpro_family/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..4f0c6d23e626a859001a96ef14bcf20a3646c510 --- /dev/null +++ b/interpro_family/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:190cf4bcff28de14588740304178704a7e781a9b18fa88e0133ffcff48bd4e7b +size 139877 diff --git a/interpro_family/consensus.joblib b/interpro_family/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7bf5925786449cd25922c01eeb2ece9471508298 --- /dev/null +++ b/interpro_family/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:7ec895fa50b919e19f80ca935e9dbff1364ef9f80c93e445c17a33eeb0fa62eb +size 928724 diff --git a/interpro_family/df_merge.tsv b/interpro_family/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..34f9ab37301161ee93c29d74db6608660926ac4b --- /dev/null +++ b/interpro_family/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Proteasome B-type subunit [IPR023333] 5 7 2.5268994704617342 0.011507443681116 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 1.0 0.04159641685533 0.003087611696091 1.4679347449836997e-08 9.533521740063692e-07 +Proteasome, subunit alpha/beta [IPR001353] 6 14 2.4005582387551905 0.0163700856027475 5.075242718446602 13.970873786407768 1.2284854682369022 0.3020132543529001 2.3027355385508845 0.1681602725795027 1.1101966392985694 0.3179790146746512 1.0 0.0727733471903131 0.0098557770733155 1.2136189316509023e-06 4.818994730788961e-06 +Major facilitator superfamily [IPR011701] 3 7 2.2129288549223904 0.0269025509867724 1.900485436893204 4.145631067961165 1.0239318262629833 0.2378354197978781 1.3191273068698348 1.552684909115802 1.329586452483978 0.2573287434106264 1.0 0.0001849020150097 7.068071174135657e-05 0.0024022577840735 0.0271057364081029 diff --git a/interpro_family/metrics.json b/interpro_family/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..6b807947f058e1574e9a1c44d6e92d50b022c58a --- /dev/null +++ b/interpro_family/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 2790, + "title": "Average number of proteins per term", + "value": 1.2971326164874553 +} \ No newline at end of file diff --git a/interpro_family/paths.json b/interpro_family/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..e711a50a1c2b31621ef28c6b84bf4834566a718d --- /dev/null +++ b/interpro_family/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_family/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/interpro_family/result.tsv b/interpro_family/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..75645f2e51aad85daf1e7f2da33d30566a447bba --- /dev/null +++ b/interpro_family/result.tsv @@ -0,0 +1,132 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Amyloidogenic glycoprotein [IPR008155] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.9999999995649688 0.0149843320457569 2 P05067 1 +Palmitoyl protein thioesterase [IPR002472] 0.9791266135677013 2.622734754829009 0.0087227151901807 0.9999999999757628 0.0164937708120523 2 P50897 1 +V-type ATPase, V0 complex, 116kDa subunit family [IPR002490] 0.9777533644603128 2.617144238565863 0.0088668864240579 0.9999999999838476 0.0167152791372444 2 Q9Y487 1 +ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028] 0.9777533644603128 2.617144238565863 0.0088668864240579 0.9999999999838476 0.0167152791372444 2 Q9Y487 1 +Nucleobindin [IPR040250] 0.974732216424059 2.6048332452350484 0.009191898450696 0.999999999993531 0.0172415950561617 2 Q02818 1 +Beta-1,4-galactosyltransferase [IPR003859] 0.9689645701730294 2.5812851549829428 0.0098433238508726 0.9999999999989674 0.0182356398034094 2 O60512 1 +Amino acid/polyamine transporter I [IPR002293] 0.960999725350178 2.548668633664815 0.0108134992869404 0.9999999999999328 0.0197316304843451 2 P30825 1 +Proteasome B-type subunit [IPR023333] 0.9137222768796688 2.5268994704617342 0.011507443681116 0.9999999999999906 0.0206968923657576 7 P28074,P20618,P28072,Q99436,P49721 5 +Alpha-L-fucosidase, metazoa-type [IPR016286] 0.9376544905245802 2.4524158380675924 0.0141900569845192 1.0 0.0245597140116679 2 Q9BTY2 1 +Glycoside hydrolase, family 29 [IPR000933] 0.9376544905245802 2.4524158380675924 0.0141900569845192 1.0 0.0245597140116679 2 Q9BTY2 1 +Histidine phosphatase superfamily, clade-2 [IPR000560] 0.9335347432024158 2.4353292079727376 0.0148782464950083 1.0 0.0254820796323347 2 Q9NPH0 1 +CD36 family [IPR002159] 0.9291403460587732 2.4170702164314375 0.0156459986201298 1.0 0.0266497778694519 2 Q8WTV0 1 +Proteasome, subunit alpha/beta [IPR001353] 0.7355338188402893 2.4005582387551905 0.0163700856027475 1.0 0.0276133850251908 14 P28070,P28074,P20618,P28072,Q99436,P49721 6 +Major facilitator, sugar transporter-like [IPR005828] 0.9209008514144446 2.382742284792231 0.0171842197940224 1.0 0.0287261673009721 2 Q7L0J3 1 +Calcium uptake protein 1/2/3 [IPR039800] 0.914583905520461 2.356342885058242 0.0184558731208528 1.0 0.030504671805201 2 Q8IYU8 1 +Rho-associated protein kinase 1/2 [IPR020684] 0.9090909090909094 2.3333297202576393 0.0196308467414296 1.0 0.0320105566385673 2 O75116 1 +Cytoplasmic FMR1-interacting [IPR008081] 0.9055204614117004 2.31834273780482 0.0204307014514135 1.0 0.0330444388692428 2 Q96F07 1 +Dedicator of cytokinesis [IPR026791] 0.890964020873384 2.2570115318948676 0.0240073541977161 1.0 0.0377142557497905 2 Q14185 1 +Major facilitator superfamily [IPR011701] 0.8369411636590772 2.2129288549223904 0.0269025509867724 1.0 0.0414228020160568 7 Q7L0J3,Q6NT16,P53985 3 +Ribonucleotide reductase small subunit family [IPR000358] 0.8728371326558649 2.1801251703206916 0.0292481844650627 1.0 0.0442769585770618 2 Q7LG56 1 +Ribonucleotide reductase small subunit [IPR033909] 0.8728371326558649 2.1801251703206916 0.0292481844650627 1.0 0.0442769585770618 2 Q7LG56 1 +Gamma-tubulin complex component protein [IPR007259] 0.8632243889041445 2.139125517370854 0.032425504311548 1.0 0.0482234312522488 2 Q96CW5 1 +Peptidase T1A, proteasome beta-subunit [IPR000243] 0.9590659340659342 2.1039002557374764 0.0353871486810655 1.0 0.0516641260178821 3 Q99436,P28074 2 +Alpha-catenin [IPR001033] 0.8492172480087872 2.079107748304495 0.0376074480941786 1.0 0.0543651710791493 2 Q9UBT7 1 +Porin, eukaryotic type [IPR001925] 0.9462990317780916 2.055796231707351 0.0398021614140833 1.0 0.0567000665250027 3 P21796 1 +Tetraspanin/Peripherin [IPR018499] 0.8437242515792335 2.0554837378839133 0.0398323047989266 1.0 0.0567000665250027 2 O60637 1 +Tetraspanin, animals [IPR000301] 0.8437242515792335 2.0554837378839133 0.0398323047989266 1.0 0.0567000665250027 2 O60637 1 +Transmembrane protein GPR107/GPR108-like [IPR009637] 0.9392857142857148 2.029280892178584 0.0424296883873331 1.0 0.0596968384269589 3 Q9NPR9,Q5VW38 2 +Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699] 0.8299917605053522 1.9962127584442373 0.0459107693013978 1.0 0.0635372253724702 2 Q13868 1 +Mpv17/PMP22 [IPR007248] 0.9244505494505498 1.97298730319271 0.0484970089253655 1.0 0.0665024252470534 3 Q9NR77,Q567V2 2 +Sec13/Seh1 family [IPR037363] 0.8223015655039789 1.9628922963338504 0.0496586901055562 1.0 0.0677495087503676 2 P55735 1 +Prenylcysteine oxidase [IPR017046] 0.8214776160395486 1.9593168783682715 0.0500756883132607 1.0 0.0681850514367971 2 Q9UHG3 1 +Cohesin subunit Scc3/SA [IPR039662] 0.8209283163965932 1.956932694432007 0.0503553820364595 1.0 0.0684990326093232 2 Q8WVM7 1 +SLC12A transporter family [IPR004842] 0.8170832188959074 1.94023066607398 0.052351663226561 1.0 0.0707317871196635 2 P55011 1 +Aminopeptidase N-type [IPR034016] 0.8816553070273664 1.8988102017939064 0.0575894353709713 1.0 0.0762936964316287 4 Q9UIQ6,P55786 2 +Peptidase S10, serine carboxypeptidase [IPR001563] 0.903846153846154 1.894351738414526 0.0581783378279663 1.0 0.0769171412646957 3 Q9HB40,P10619 2 +Mitochondrial carrier UCP-like [IPR002030] 0.8058225762153224 1.891191581635308 0.0585987747085499 1.0 0.0772639798850918 2 Q9UBX3 1 +Microtubule-associated protein RP/EB [IPR027328] 0.7978577313924721 1.8563951936210343 0.0633972493183305 1.0 0.082614818121505 2 Q15555 1 +Ubiquitin conjugation factor E4 [IPR045132] 0.797583081570994 1.8551937326634695 0.0635685663471181 1.0 0.0827993931412043 2 O95155 1 +Tropomyosin [IPR000533] 0.8901098901098906 1.8416498828400123 0.0655263794472271 1.0 0.0846774426390754 3 P67936,P09493 2 +HnRNP R/Q splicing factor [IPR006535] 0.7882449876407568 1.814282847182926 0.0696341909546212 1.0 0.0888944699244511 2 O43390 1 +Eukaryotic porin/Tom40 [IPR027246] 0.8545283315463459 1.7937142338709169 0.0728587922315089 1.0 0.0923870052019344 4 P21796 1 +THRAP3/BCLAF1 family [IPR029199] 0.7811040922823386 1.7829200598649264 0.0745993171659546 1.0 0.0942627241363286 2 Q9NYF8 1 +Sister chromatid cohesion protein Pds5 [IPR039776] 0.7808294424608578 1.7817124898723862 0.0747961290711092 1.0 0.0944686283876843 2 Q29RF7 1 +Vinculin/alpha-catenin [IPR006077] 0.8483729974927365 1.6802756698642731 0.0929036925662354 1.0 0.1121112899047564 3 Q9UBT7 1 +Transmembrane protein 126 [IPR009801] 0.7566602581708302 1.675091763346621 0.0939162287726045 1.0 0.113137425853008 2 Q9H061 1 +P-type ATPase [IPR001757] 0.7327228967970489 1.5935355599975791 0.1110400975612098 1.0 0.1300049820376732 6 P16615 1 +Nonaspanin (TM9SF) [IPR004240] 0.8215796603252228 1.5758321385085814 0.1150644936354243 1.0 0.1335954795018035 3 Q9HD45 1 +Translation initiation factor IF- 2 [IPR015760] 0.7322164240593204 1.5666376314022687 0.1171994165517571 1.0 0.1355664892949429 2 P46199 1 +Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930] 0.7242639521483516 1.5579162412450842 0.1192531046464844 1.0 0.1373157911529886 6 Q9UIQ6,P55786 2 +Ribosomal protein L24e-related [IPR000988] 0.7267234276297689 1.5421960385014823 0.1230259624634679 1.0 0.1406154999070363 2 Q9UHA3 1 +SOUL haem-binding protein [IPR006917] 0.7184839329854402 1.5054947728689694 0.1321969197279271 1.0 0.1496265338908384 2 Q9Y5Z4 1 +Integrin alpha chain [IPR000413] 0.7151881351277088 1.4908027346554398 0.1360132936031362 1.0 0.1528916555812852 2 P17301 1 +TAF15/EWS/TLS family [IPR034870] 0.7837912087912093 1.4277177230983258 0.1533731228123951 1.0 0.1693355807861426 3 P35637,Q01844 2 +Ras GTPase-activating protein-binding protein [IPR039539] 0.6901950013732451 1.3792415406116407 0.1678202941104443 1.0 0.1848474617323883 2 Q9UN86 1 +Structural maintenance of chromosomes protein [IPR024704] 0.7463588898048973 1.367455150861531 0.1714826857653264 1.0 0.1885836394502407 4 O95347,Q9UQE7,Q9NTJ3 3 +ATPase family AAA domain-containing protein 3 [IPR039188] 0.6808569074430059 1.3375283871748371 0.1810502225546795 1.0 0.1985574374715235 2 Q5T9A4 1 +Ergosterol biosynthesis ERG4/ERG24 [IPR001171] 0.7540594951154558 1.3108306991355558 0.1899149683364818 1.0 0.2080340642555101 3 Q9UBM7 1 +Oxysterol-binding protein [IPR000648] 0.6564318205937275 1.2701643146512247 0.2040261061161021 1.0 0.2225304284847244 6 Q9H4L5 1 +Arginine-tRNA ligase [IPR001278] 0.6646525679758262 1.265173988611413 0.2058089646327749 1.0 0.2242996137990008 2 P54136 1 +Peptidase, FtsH [IPR005936] 0.6638286185113931 1.2614973734562842 0.2071297057026968 1.0 0.2256508703282015 2 Q9Y4W6 1 +Taxilin family [IPR026183] 0.6608074704751393 1.2480193991007638 0.2120239531001062 1.0 0.2308925952963686 2 P40222 1 +Ribosomal protein L22/L17 [IPR001063] 0.657511672617408 1.2333220722211666 0.2174556261349729 1.0 0.2367152543568375 2 Q9NWU5 1 +Fragile X mental retardation syndrome-related protein [IPR040148] 0.7280219780219789 1.2085073346151078 0.2268521762534294 1.0 0.2465592410389825 3 P51114,P51116 2 +Nucleosome assembly protein (NAP) [IPR002164] 0.6949926271104224 1.163289815191387 0.2447119365186645 1.0 0.2650412666487088 4 Q99733,Q01105 2 +GDP-fucose protein O-fucosyltransferase [IPR019378] 0.6388354847569295 1.150200328613861 0.2500613709238335 1.0 0.2704152034408897 2 Q9Y2G5 1 +Pre-mRNA-splicing factor Syf1-like [IPR045075] 0.7106260285552586 1.1403161575815723 0.254154608687239 1.0 0.2747351252372711 3 Q9BZJ0 1 +Transcription factor STAT [IPR001217] 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.276219581961319 2 P42224 1 +HnRNP-L/PTB [IPR006536] 0.6347157374347652 1.1319138365187538 0.2576706609503119 1.0 0.2783202261135773 2 P26599 1 +Kinesin light chain [IPR002151] 0.62372974457566 1.0832662339523982 0.2786902682658163 1.0 0.2999791082027884 2 Q07866 1 +Cell cycle and apoptosis regulator protein [IPR025224] 0.623180444932705 1.0808388587707467 0.2797687997016291 1.0 0.3010238916959296 2 Q8IX12 1 +Basigin-like [IPR043204] 0.6190606976105405 1.0626505169692702 0.2879404688203446 1.0 0.3094583620989066 2 P35613 1 +Dynamin [IPR022812] 0.6686697651520559 1.0591394736660211 0.2895362651006725 1.0 0.3109338643690825 4 O60313,Q9UQ16 2 +Ribosomal protein L15 [IPR030878] 0.616588849217242 1.0517526023277817 0.2929130701742761 1.0 0.3144391942232514 2 P46776 1 +cAMP-dependent protein kinase regulatory subunit [IPR012198] 0.6127437517165552 1.0348243790193694 0.3007509354673354 1.0 0.3226048096708442 2 P13861 1 +Syntaxin [IPR045242] 0.547054403710347 0.9445341580482246 0.3448967551460793 1.0 0.3681185718659377 7 O15400,O43752,O60499 3 +Mitochondrial carrier protein [IPR002067] 0.4591676524699007 0.8955342061797019 0.3705015888642036 1.0 0.3949940515594681 14 Q9HC21,Q86VD7,Q96H78 3 +Methylthiotransferase [IPR005839] 0.5773139247459417 0.8806246688788618 0.3785210019820666 1.0 0.4024670714672126 2 Q96SZ6 1 +Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554] 0.6230968336919831 0.8038811605745326 0.4214656113156181 1.0 0.4455813018456137 3 Q13362 1 +Glutathione Transferase family [IPR040079] 0.4496349855828456 0.7235878811964925 0.4693187836497685 1.0 0.4941129835406997 10 Q13505 1 +Peptidase C2, calpain family [IPR022684] 0.5919576312332964 0.6894691235228179 0.4905280972263874 1.0 0.5154702038650173 3 O15484 1 +Ezrin/radixin/moesin [IPR011174] 0.5823565411671765 0.6550796698300458 0.512416460713812 1.0 0.5372573939840419 3 P26038 1 +Clathrin light chain [IPR000996] 0.5223839604504169 0.6518300734440897 0.5145107988129043 1.0 0.5392506118287014 2 P09497 1 +ATP-dependent RNA helicase Ski2-like [IPR016438] 0.515243065091999 0.6234368280833855 0.5329975030275118 1.0 0.5569524469838044 2 Q15477 1 +Ribosome biogenesis protein Bms1/Tsr1 [IPR039761] 0.511397967591312 0.6083092571305772 0.5429823825047484 1.0 0.5669613949057815 2 Q14692 1 +Core histone macro-H2A [IPR021171] 0.5050810216973282 0.583715788320123 0.5594115431946833 1.0 0.5828073956359845 2 O75367 1 +Histone deacetylase family [IPR000286] 0.5020598736610726 0.5720723475786397 0.5672729620269941 1.0 0.590116168551571 2 Q92769 1 +Histone deacetylase [IPR003084] 0.5020598736610726 0.5720723475786397 0.5672729620269941 1.0 0.590116168551571 2 Q92769 1 +KH domain-containing BBP-like [IPR045071] 0.5568103075993124 0.5660955615619139 0.5713288203497147 1.0 0.5941138310755513 3 Q96PU8 1 +Vesicle-associated membrane-protein-associated protein [IPR016763] 0.499038725624819 0.5605086640911222 0.5751325316315756 1.0 0.5976237479523635 2 Q9P0L0 1 +Aurora kinase [IPR030616] 0.4877780829442363 0.518147828170268 0.6043551322541287 1.0 0.6268218657951744 2 O14965 1 +Mini-chromosome maintenance protein [IPR031327] 0.4693010950786808 0.504919649999497 0.6136152720499768 1.0 0.6359534208838912 6 Q14566 1 +Tight junction protein ZO [IPR005417] 0.4550947541883995 0.402743899135714 0.6871366357480122 1.0 0.7089908334826013 2 Q07157 1 +Heterogeneous nuclear ribonucleoprotein C [IPR017347] 0.451249656687716 0.3899993222459433 0.696537048096977 1.0 0.7184245338966972 2 P07910 1 +Ribosomal protein L13 [IPR005822] 0.4507003570447634 0.3881942290564076 0.6978723035187699 1.0 0.7195357453131442 2 Q9BYD1 1 +Serine hydroxymethyltransferase [IPR001085] 0.4498764075803242 0.3854939649025412 0.6998714769571315 1.0 0.7213304103104532 2 P34897 1 +Ribosomal protein L7, eukaryotic [IPR005998] 0.448777808294416 0.3819074523331101 0.702530012370373 1.0 0.7235358931389224 2 Q6DKI1 1 +Ribosomal protein L7/L30 [IPR039699] 0.448777808294416 0.3819074523331101 0.702530012370373 1.0 0.7235358931389224 2 Q6DKI1 1 +Glycosyl transferase, family 35 [IPR000811] 0.4482285086514592 0.3801201580139388 0.7038562229621452 1.0 0.7243669723586813 2 P06737 1 +Glycogen/starch/alpha-glucan phosphorylase [IPR011833] 0.4482285086514592 0.3801201580139388 0.7038562229621452 1.0 0.7243669723586813 2 P06737 1 +Prolyl 4-hydroxylase [IPR045054] 0.4457566602581646 0.372126940030902 0.7097983391456058 1.0 0.7302128931475811 2 P13674 1 +Desmosomal cadherin [IPR009122] 0.4432848118648622 0.3642158074846429 0.7156968638139953 1.0 0.7360096756509572 2 Q14126 1 +RNA (C5-cytosine) methyltransferase [IPR023267] 0.4734817257488513 0.3587186287547532 0.7198055909459551 1.0 0.7396897232925285 4 Q96P11,Q96CB9,Q08J23 3 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666] 0.4415650289389746 0.332096656492112 0.7398162747340256 1.0 0.7594140568461851 5 Q9Y3C6 1 +Tryptophan-tRNA ligase [IPR002306] 0.4257072232902932 0.3104309830710539 0.7562332360149595 1.0 0.7759804076799327 2 Q9UGM6 1 +Ribosomal protein S5 [IPR000851] 0.4246086240043892 0.3072188875120454 0.7586767700938803 1.0 0.7778725898272891 2 P82675 1 +DnaJ homolog subfamily A member 1/2-like [IPR044713] 0.4202142268607457 0.2945531008497458 0.768335293423626 1.0 0.7869513467885156 2 O60884 1 +Vacuolar protein sorting-associated protein 33 [IPR027121] 0.4122493820378954 0.2723559304315974 0.7853483546776621 1.0 0.8040814346974963 2 Q9H267 1 +TB2/DP1/HVA22-related protein [IPR004345] 0.4295136026381093 0.2413484378472302 0.8092850722261375 1.0 0.8265016951939905 4 Q9H6H4,Q00765,Q6NUK4 3 +Exportin-1/5 [IPR045065] 0.4004394397143576 0.2413034469671854 0.8093199395232911 1.0 0.8265016951939905 2 Q9HAV4 1 +Kinesin-like protein [IPR027640] 0.3448191125419414 0.2306133484064025 0.8176151965844876 1.0 0.8340571840843585 9 Q14807,Q02241,Q9Y496,P33176 4 +G-protein alpha subunit, group I [IPR001408] 0.4240175872492651 0.2283619260693122 0.8193648860532408 1.0 0.8352312868427262 4 P09471,P63096,P04899 3 +Protein PRRC2 [IPR033184] 0.3946717934633268 0.2269697247362094 0.8204472839925505 1.0 0.8360291900435413 2 Q9Y520 1 +Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936] 0.4281602650542349 0.2038924913841284 0.8384375128389396 1.0 0.8534259981104129 3 Q9Y3C6 1 +Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237] 0.4154691239454352 0.1785928420689832 0.8582574153294877 1.0 0.8726451125252445 3 Q9H9Q2 1 +Bcl2-like [IPR002475] 0.4092641875100391 0.1670161464291755 0.8673573443554108 1.0 0.8802977910323125 3 Q9BXK5 1 +Bcl-2 family [IPR026298] 0.4092641875100391 0.1670161464291755 0.8673573443554108 1.0 0.8802977910323125 3 Q9BXK5 1 +AP-1/2/4 complex subunit beta [IPR016342] 0.3674814611370466 0.1670108455712655 0.8673615152501173 1.0 0.8802977910323125 2 Q10567 1 +Ribosomal protein S15 [IPR000589] 0.366382861851132 0.1648565911337486 0.8690568600720217 1.0 0.8816976871276148 2 P82914 1 +Lysosome-associated membrane glycoprotein [IPR002000] 0.3490799230980458 0.1336870380355171 0.893650055299499 1.0 0.9053317553687736 2 P11279 1 +DNA-directed RNA polymerase, subunit beta-prime [IPR045867] 0.376098901098903 0.1140314759415882 0.9092128419843148 1.0 0.9200956942822772 3 O14802,O95602 2 +Glutamyl/glutaminyl-tRNA synthetase [IPR000924] 0.3747252747252768 0.1121575211995921 0.910698509762035 1.0 0.9212649899333132 3 P07814,Q5JPH6 2 +Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238] 0.3331502334523437 0.109516568139414 0.91279278133435 1.0 0.923048880001028 2 Q9Y5J9 1 +AP complex subunit beta [IPR026739] 0.3675824175824194 0.1028152127349638 0.918109631236038 1.0 0.927752941379408 3 O00203,Q10567 2 +Luc7-related [IPR004882] 0.3262839879154031 0.100395913504194 0.9200300139280624 1.0 0.9291215113625512 2 Q9Y383 1 +Clathrin adaptor, mu subunit [IPR001392] 0.3465237702665641 0.0897039998475197 0.928522437340837 1.0 0.9372567294431748 4 Q9BXS5,Q9Y2T2,Q96CW1 3 +Zinc/iron permease [IPR003689] 0.3546492108205418 0.0875837783867113 0.9302074955991212 1.0 0.9382787103114778 3 Q8N1S5 1 +ADP/ATP carrier protein, eukaryotic type [IPR002113] 0.3489010989011006 0.0814912080060933 0.9350513166198168 1.0 0.9424830828646276 3 P12236,P05141 2 +P-type ATPase, subfamily IIB [IPR006408] 0.2952485580884315 0.0682085605106734 0.9456196125420346 1.0 0.9514167756914088 2 P20020 1 +Tricarboxylate/iron carrier [IPR004686] 0.2875966290745738 0.0390447833397208 0.968854683874666 1.0 0.9733901937379612 3 Q6P4A7 1 +Ezrin/radixin/moesin-like [IPR000798] 0.2382346390495874 0.0130876521317186 0.9895578625275648 1.0 0.9920468690089492 7 P15311,O43491,P26038 3 diff --git a/interpro_family/selections.json b/interpro_family/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8751d47b7eee31da7f9d526d80043454f7b4f681 --- /dev/null +++ b/interpro_family/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["(Uracil-5)-methyltransferase family [IPR010280]", "1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase, eukaryotes [IPR027496]", "1-Cys peroxiredoxin [IPR045020]", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 [IPR028380]", "14-3-3 protein [IPR000308]", "14-3-3 theta [IPR042584]", "18S rRNA (guanine(1575)-N(7))-methyltransferase Bud23-like [IPR039769]", "2-amino-3-ketobutyrate coenzyme A ligase [IPR011282]", "2-deoxynucleoside 5-phosphate N-hydrolase 1, DNPH1 [IPR028607]", "2-oxoglutarate and iron-dependent oxygenase domain-containing protein 3 [IPR039210]", "2-oxoglutarate dehydrogenase E1 component [IPR011603]", "2-phosphoglycolate phosphatase, eukaryotic [IPR006349]", "26S Proteasome non-ATPase regulatory subunit 1 [IPR035266]", "26S Proteasome non-ATPase regulatory subunit 11 [IPR035295]", "26S Proteasome non-ATPase regulatory subunit 12 [IPR035297]", "26S Proteasome non-ATPase regulatory subunit 12/COP9 signalosome complex subunit 4 [IPR040134]", "26S Proteasome non-ATPase regulatory subunit 13 [IPR035298]", "26S Proteasome non-ATPase regulatory subunit 14 [IPR035299]", "26S Proteasome non-ATPase regulatory subunit 6 [IPR035268]", "26S Proteasome non-ATPase regulatory subunit 7/8 [IPR033858]", "26S Proteasome non-ATPase regulatory subunit 9 [IPR035269]", "26S Proteasome regulatory subunit 4 [IPR035244]", "26S Proteasome regulatory subunit 6A [IPR035254]", "26S Proteasome regulatory subunit 6B [IPR035256]", "26S Proteasome regulatory subunit 7 [IPR035245]", "26S proteasome non-ATPase regulatory subunit 10-like [IPR039334]", "26S proteasome non-ATPase regulatory subunit 3 [IPR035267]", "26S proteasome non-ATPase regulatory subunit Rpn12 [IPR006746]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn1 subunit [IPR016643]", "26S proteasome regulatory complex, non-ATPase subcomplex, Rpn2/Psmd1 subunit [IPR016642]", "26S proteasome regulatory subunit 10B [IPR035263]", "26S proteasome regulatory subunit P45-like [IPR005937]", "26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1 [IPR019585]", "28S ribosomal protein S17, mitochondrial [IPR039193]", "28S ribosomal protein S24, mitochondrial [IPR026146]", "28S ribosomal protein S25, mitochondrial [IPR040049]", "28S ribosomal protein S26 [IPR026140]", "28S ribosomal protein S27, mitochondrial [IPR019266]", "28kDa heat- and acid-stable phosphoprotein [IPR039876]", "3-hydroxyacyl-CoA dehydrogenase [IPR022694]", "3-hydroxyisobutyrate dehydrogenase [IPR011548]", "3-hydroxyisobutyrate dehydrogenase-related [IPR015815]", "3-keto-steroid reductase [IPR042829]", "3-ketodihydrosphingosine reductase KDSR-like [IPR045022]", "3-oxo-5-alpha-steroid 4-dehydrogenase/very-long-chain enoyl-CoA reductase [IPR039357]", "3-oxoacid CoA-transferase [IPR014388]", "39S ribosomal protein L40, mitochondrial [IPR039145]", "39S ribosomal protein L43/54S ribosomal protein L51 [IPR039927]", "39S ribosomal protein L46, mitochondrial [IPR040008]", "4-aminobutyrate aminotransferase, eukaryotic [IPR004631]", "40S Ribosomal protein S10 [IPR037447]", "40S ribosomal protein S1/3, eukaryotes [IPR027500]", "40S ribosomal protein S29/30S ribosomal protein S14 type Z [IPR039744]", "40S ribosomal protein SA [IPR027504]", "4F2 cell-surface antigen heavy chain [IPR042280]", "5'-3' exoribonuclease [IPR027073]", "5'-3' exoribonuclease type 2 [IPR017151]", "5'-AMP-activated protein kinase subunit gamma-1 [IPR039166]", "5'-deoxynucleotidase YfbR/HDDC2 [IPR039356]", "5-lipoxygenase-activating protein [IPR001446]", "50S ribosomal protein L18Ae/60S ribosomal protein L20 and L18a [IPR028877]", "50S ribosomal protein uL4 [IPR013005]", "6-Phosphogluconolactonase [IPR039104]", "6-phosphogluconate dehydrogenase [IPR006183]", "6-phosphogluconate dehydrogenase, decarboxylating [IPR006113]", "60S acidic ribosomal protein P0 [IPR030670]", "60S ribosomal protein L18a/ L20, eukaryotes [IPR021138]", "60S ribosomal protein L19 [IPR039547]", "60S ribosomal protein L35 [IPR045059]", "60S ribosomal protein L6E [IPR000915]", "60kDa SS-A/Ro ribonucleoprotein [IPR040322]", "A-kinase anchor protein 12 [IPR028540]", "A-kinase anchor protein 13 [IPR028852]", "A-kinase anchor protein 17A [IPR034355]", "A-kinase anchoring protein 95 (AKAP95) [IPR007071]", "AAA ATPase, CDC48 family [IPR005938]", "ABC transporter Tap-like [IPR013305]", "ABI family [IPR028457]", "ABT1/Esf2 [IPR039119]", "ADF/Cofilin [IPR017904]", "ADP-ribose pyrophosphatase, mitochondrial [IPR039989]", "ADP-ribosylation factor 1-5 [IPR045872]", "ADP-ribosylation factor 6 [IPR041838]", "ADP-ribosylation factor-like protein 10 [IPR042951]", "ADP-ribosylation factor-like protein 2 [IPR045873]", "ADP-ribosylation factor-like protein 2/3 [IPR044612]", "ADP-ribosylation factor-like protein 6 [IPR041839]", "ADP-ribosylation factor-like protein 6-interacting protein 1 [IPR033301]", "ADP-ribosylation factor-like protein 6-interacting protein 6 [IPR029383]", "ADP-ribosylation factor-like protein 8A/8B [IPR044154]", "ADP-specific phosphofructokinase/glucokinase [IPR007666]", "ADP/ATP carrier protein, eukaryotic type [IPR002113]", "AH receptor-interacting protein [IPR031208]", "AIP/AIPL1 [IPR039663]", "AMP deaminase 2 [IPR029749]", "AMP deaminase [IPR006329]", "AP complex subunit beta [IPR026739]", "AP endonuclease 1 [IPR004808]", "AP-1 complex subunit sigma [IPR044733]", "AP-1/2/4 complex subunit beta [IPR016342]", "AP-2 complex subunit sigma [IPR027156]", "AP-3 complex subunit beta [IPR026740]", "AP-3 complex subunit sigma [IPR027155]", "ARMET-like [IPR045333]", "AT-rich interactive domain-containing protein 3 [IPR045147]", "ATP synthase membrane subunit K [IPR009125]", "ATP synthase subunit ATP5MJ, mitochondrial [IPR012574]", "ATP synthase, F0 complex, subunit A [IPR000568]", "ATP synthase, F0 complex, subunit A, bacterial/mitochondria [IPR045083]", "ATP synthase, F0 complex, subunit B [IPR013837]", "ATP synthase, F0 complex, subunit B/MI25 [IPR008688]", "ATP synthase, F0 complex, subunit D, mitochondrial [IPR008689]", "ATP synthase, F0 complex, subunit E, mitochondrial [IPR008386]", "ATP synthase, F0 complex, subunit G, mitochondrial [IPR006808]", "ATP synthase, F1 complex, alpha subunit [IPR005294]", "ATP synthase, F1 complex, beta subunit [IPR005722]", "ATP synthase, F1 complex, gamma subunit [IPR000131]", "ATP synthase-coupling factor 6, mitochondrial [IPR008387]", "ATP-binding cassette sub-family C member 4 [IPR030240]", "ATP-binding cassette subfamily B member 10-like [IPR030260]", "ATP-citrate synthase [IPR014608]", "ATP-dependent 6-phosphofructokinase [IPR022953]", "ATP-dependent 6-phosphofructokinase, eukaryotic-type [IPR009161]", "ATP-dependent 6-phosphofructokinase, vertebrate-type [IPR041914]", "ATP-dependent Clp protease proteolytic subunit [IPR001907]", "ATP-dependent RNA helicase DHX29 [IPR034730]", "ATP-dependent RNA helicase Ski2-like [IPR016438]", "ATP-dependent helicase Rad3/Chl1-like [IPR013020]", "ATP11 [IPR010591]", "ATP12, ATP synthase F1-assembly protein [IPR011419]", "ATP:cob(I)alamin adenosyltransferase, PduO-type [IPR029499]", "ATP:guanido phosphotransferase [IPR000749]", "ATPase family AAA domain-containing protein 2 [IPR031252]", "ATPase family AAA domain-containing protein 3 [IPR039188]", "ATPase family AAA domain-containing protein ATAD2-like [IPR045199]", "ATPase, OSCP/delta subunit [IPR000711]", "ATPase, V0 complex, c/d subunit [IPR002843]", "ATPase, V0 complex, subunit 116kDa, eukaryotic [IPR026028]", "ATPase, V0 complex, subunit d [IPR016727]", "ATPase, V1 complex, subunit A [IPR005725]", "ATPase, V1 complex, subunit B [IPR005723]", "ATPase, V1 complex, subunit C [IPR004907]", "ATPase, V1 complex, subunit D [IPR002699]", "ATPase, V1 complex, subunit H [IPR004908]", "ATPase, vacuolar ER assembly factor, Vma12 [IPR021013]", "Abl interactor 1 [IPR028456]", "Abr/Bcr [IPR037769]", "Acetyl-coenzyme A transporter 1-like [IPR024371]", "Acid ceramidase-like [IPR016699]", "Acidic leucine-rich nuclear phosphoprotein 32 [IPR045081]", "Acireductone dioxygenase ARD family [IPR004313]", "Aconitase, mitochondrial-like [IPR006248]", "Aconitase/Iron-responsive element-binding protein 2 [IPR006249]", "Actin family [IPR004000]", "Actin-related protein 10 [IPR027127]", "Actin-related protein 2/3 complex subunit 2 [IPR007188]", "Actin-related protein 2/3 complex subunit 3 [IPR007204]", "Actin-related protein 2/3 complex subunit 4 [IPR008384]", "Actin-related protein 3 [IPR015623]", "Actin-related protein 6 [IPR030054]", "Actin-related protein 8/Plant actin-related protein 9 [IPR027668]", "Activating signal cointegrator 1 complex subunit 1 [IPR009210]", "Activating signal cointegrator 1-like [IPR039128]", "Activator of 90kDa heat shock protein ATPase-like [IPR039981]", "Activator of Hsp90 ATPase homologue 1-like [IPR013538]", "Active zone protein ELKS [IPR019323]", "Activity-dependent neuroprotector homeobox protein [IPR038861]", "Acyl-CoA desaturase [IPR015876]", "Acyl-CoA oxidase [IPR012258]", "Acyl-CoA thioesterase [IPR003703]", "Acyl-CoA thioesterase, long chain [IPR016662]", "Acyl-coenzyme A thioesterase 13 [IPR039298]", "Acylneuraminate cytidylyltransferase [IPR003329]", "Acyltransferase ChoActase/COT/CPT [IPR000542]", "Adaptor protein complex AP-1, gamma subunit [IPR017107]", "Adaptor protein complex AP-2, alpha subunit [IPR017104]", "Adaptor protein complex AP-3, delta subunit [IPR017105]", "Adaptor protein complex, sigma subunit [IPR016635]", "Adenine phosphoribosyl transferase [IPR005764]", "Adenosine deaminase [IPR028893]", "Adenosine kinase [IPR001805]", "Adenosine/adenine deaminase [IPR006330]", "Adenosylhomocysteinase-like [IPR000043]", "Adenylate cyclase-associated CAP [IPR001837]", "Adenylate kinase 2 [IPR028587]", "Adenylate kinase 3/4, mitochondrial [IPR028586]", "Adenylate kinase 4, mitochondrial [IPR028585]", "Adenylate kinase isoenzyme 1 [IPR028582]", "Adenylate kinase subfamily [IPR006259]", "Adenylate kinase, isozyme 1/5 [IPR006267]", "Adenylate kinase/UMP-CMP kinase [IPR000850]", "Adenylosuccinate lyase [IPR004769]", "Adenylosuccinate synthetase [IPR001114]", "Adenylosuccinate synthetase isozyme 2, chordates [IPR027529]", "Adenylyl cyclase-associated protein CAP1 [IPR028415]", "Adenylyl-sulfate kinase [IPR002891]", "AdoMet-dependent rRNA methyltransferase Spb1-like [IPR028589]", "Aladin [IPR045139]", "Alanine-tRNA ligase, class IIc [IPR002318]", "Alanine-tRNA ligase, eukaryota/bacteria [IPR023033]", "Alcohol dehydrogenase class III [IPR014183]", "Aldehyde dehydrogenase NAD(P)-dependent [IPR012394]", "Aldehyde dehydrogenase [IPR011408]", "Aldehyde dehydrogenase family 7 member A1-like [IPR044638]", "Aldo-keto reductase [IPR020471]", "Aldo-keto reductase family 1 member A1 [IPR044481]", "Aldose 1-/Glucose-6-phosphate 1-epimerase [IPR008183]", "Aldose 1-epimerase [IPR015443]", "Alkyldihydroxyacetonephosphate synthase [IPR025650]", "Alpha E-catenin/Alpha T-catenin [IPR030047]", "Alpha-2-macroglobulin receptor-associated protein [IPR038003]", "Alpha-D-phosphohexomutase superfamily [IPR005841]", "Alpha-L-fucosidase, metazoa-type [IPR016286]", "Alpha-N-acetylglucosaminidase [IPR007781]", "Alpha-N-methyltransferase NTM1 [IPR008576]", "Alpha-adducin [IPR027766]", "Alpha-catenin [IPR001033]", "Alpha-catulin 1 [IPR030045]", "Alpha-internexin [IPR027703]", "Alpha-ketoglutarate-dependent dioxygenase FTO [IPR032868]", "Alpha/gamma-adaptin-binding protein p34 [IPR019341]", "Amidase [IPR000120]", "Amidophosphoribosyltransferase [IPR005854]", "Amino acid/polyamine transporter I [IPR002293]", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 [IPR042360]", "Aminoacyl-tRNA synthetase, class Ic [IPR002305]", "Aminopeptidase N-type [IPR034016]", "Aminopeptidase, leukotriene A4 hydrolase-like [IPR034015]", "Aminotransferase ALAT1/2-like [IPR045088]", "Aminotransferase class IV [IPR001544]", "Aminotransferase class-III [IPR005814]", "AmpG-like permease/Acetyl-coenzyme A transporter 1 [IPR004752]", "Amyloid beta precursor protein binding family B member 1/2/3 [IPR039576]", "Amyloid-beta precursor protein [IPR028866]", "Amyloidogenic glycoprotein [IPR008155]", "Anamorsin [IPR007785]", "Anaphase-promoting complex subunit 1 [IPR024990]", "Anaphase-promoting complex subunit 16 [IPR029641]", "Anaphase-promoting complex subunit 2 [IPR044554]", "Anaphase-promoting complex subunit 4 [IPR024789]", "Anaphase-promoting complex subunit 4, metazoa [IPR017169]", "Anaphase-promoting complex subunit 5 [IPR037679]", "Ancient conserved domain protein family [IPR045095]", "Angiomotin [IPR009114]", "Anion exchange protein 2 [IPR002978]", "Anion exchange protein [IPR001717]", "Ankycorbin [IPR042420]", "Ankyrin repeat and LEM domain-containing protein 2 [IPR035007]", "Annexin A1 [IPR002388]", "Annexin A11 [IPR008157]", "Annexin A2 [IPR002389]", "Annexin A3 [IPR002390]", "Annexin A6 [IPR002393]", "Annexin [IPR001464]", "Anoctamin [IPR007632]", "Anoctamin-6 [IPR031295]", "Antifreeze, type III [IPR006013]", "Antigen peptide transporter 1 [IPR013306]", "Apolipoprotein C-I [IPR006781]", "Apolipoprotein L [IPR008405]", "Apoptosis inhibitory 5 [IPR008383]", "Apoptosis regulator BAK [IPR026308]", "Apoptosis regulator, Mcl-1 [IPR013281]", "Apyrase [IPR009283]", "Arfaptin family [IPR030798]", "Arfaptin-1 [IPR030793]", "Arginase [IPR014033]", "Arginine-tRNA ligase [IPR001278]", "Armadillo repeat protein deleted in velo-cardio-facial syndrome [IPR028444]", "Armadillo repeat-containing protein 6 [IPR040104]", "Armadillo-like helical domain-containing protein 3-like [IPR039868]", "Arrestin [IPR000698]", "Arsenical pump ATPase, ArsA/GET3 [IPR016300]", "Arsenical pump ATPase, ArsA/GET3, eukaryotic [IPR027542]", "Arsenite methyltransferase-like [IPR026669]", "Arv1 protein [IPR007290]", "Arylacetamide deacetylase [IPR017157]", "Arylesterase [IPR002640]", "Ashwin [IPR024887]", "Asparagine synthase, glutamine-hydrolyzing [IPR006426]", "Asparagine-tRNA ligase [IPR004522]", "Asparaginyl endopeptidase [IPR043577]", "Aspartate carbamoyltransferase [IPR002082]", "Aspartate-tRNA ligase, type 1 [IPR004524]", "Aspartate-tRNA synthetase, type 2 [IPR004523]", "Aspartate/ornithine carbamoyltransferase [IPR006130]", "Aspartate/other aminotransferase [IPR000796]", "Aspartyl/Asparaginyl-tRNA synthetase, class IIb [IPR002312]", "Aspartyl/asparaginyl beta-hydroxylase family [IPR039038]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit [IPR004413]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, subunit B /E [IPR017959]", "Associate of Myc 1 [IPR026060]", "Ataxin2-like [IPR045117]", "Atg6/Beclin [IPR007243]", "Atypical dual specificity phosphatase, subfamily A [IPR020405]", "Atypical kinase COQ8A [IPR034640]", "Aurora kinase B [IPR028772]", "Aurora kinase [IPR030616]", "Autophagy protein Atg8 ubiquitin-like [IPR004241]", "Autophagy-related protein 5 [IPR007239]", "B-cell receptor-associated protein 29/31 [IPR008417]", "BAG family molecular chaperone regulator 2 [IPR037689]", "BBP/SF1 family [IPR031150]", "BCAS3-like [IPR045142]", "BCP1 family [IPR025602]", "BEN domain-containing protein 3 [IPR033583]", "BLOC-2 complex, Hps6 subunit [IPR017218]", "BRCA1-A complex subunit BRE [IPR010358]", "BRCA1-associated ATM activator 1 [IPR038904]", "BRCA1-associated [IPR031099]", "BRI3-binding protein [IPR033367]", "BRO1 domain-containing protein BROX [IPR038898]", "BTB-kelch protein [IPR017096]", "Bacterial/eukaryotic lysine-tRNA ligase, class II [IPR034762]", "Baculoviral IAP repeat-containing protein 6 [IPR022103]", "Band 4.1 protein, chordates [IPR021187]", "Band 4.1-like protein 2 [IPR030546]", "Band 4.1-like protein 3 [IPR030691]", "Band 4.1-like protein 5 [IPR030694]", "Band-7 stomatin-like [IPR043202]", "Bardet-Biedl syndrome 4 protein [IPR028786]", "Barrier- to-autointegration factor, BAF [IPR004122]", "Basigin [IPR044157]", "Basigin-like [IPR043204]", "Bax inhibitor 1-related [IPR006214]", "Bcl-2 family [IPR026298]", "Bcl-2-associated transcription factor 1 [IPR026668]", "Bcl-2-like protein 13 [IPR042398]", "Bcl2-like [IPR002475]", "Beclin-1 [IPR032913]", "Bet3 family [IPR016721]", "Beta tubulin [IPR002453]", "Beta-1,4-galactosyltransferase [IPR003859]", "Beta-1,4-glucuronyltransferase 1 [IPR043189]", "Beta-N-acetylglucosaminidase [IPR011496]", "Beta-catenin [IPR013284]", "Beta-catenin-like protein 1 [IPR039678]", "Beta-galactosidase 1-like [IPR026283]", "Beta-hexosaminidase [IPR025705]", "Beta-lactamase HcpB-like [IPR040239]", "Bicarbonate transporter, eukaryotic [IPR003020]", "Bicaudal-D protein [IPR018477]", "Bifunctional polynucleotide phosphatase/kinase PNKP [IPR006550]", "Bifunctional purine biosynthesis protein PurH-like [IPR002695]", "Biliverdin reductase A [IPR017094]", "Biotin--acetyl-CoA-carboxylase ligase [IPR004408]", "BolA protein [IPR002634]", "BolA-like protein 2 [IPR045115]", "Brain acid soluble protein 1 [IPR008408]", "Branched-chain amino acid aminotransferase II [IPR005786]", "Branched-chain aminotransferase [IPR033939]", "Breast cancer type 1 susceptibility protein (BRCA1) [IPR011364]", "Bromodomain adjacent to zinc finger domain protein 2A [IPR028940]", "Bud22/Serum response factor-binding protein 1 [IPR037393]", "Bystin [IPR007955]", "C-5 cytosine methyltransferase [IPR001525]", "C-terminal binding protein [IPR043322]", "C2 domain-containing protein 2-like [IPR039934]", "C2 domain-containing protein 5 [IPR038983]", "C2H2-type Zinc finger protein, YY1-like [IPR017114]", "CAAX prenyl protease 1 [IPR027057]", "CCR4-NOT complex, subunit 3/ 5 [IPR012270]", "CCR4-NOT transcription complex subunit 1 [IPR040398]", "CCR4-NOT transcription complex subunit 11 [IPR019312]", "CCR4-NOT transcription complex subunit 4 [IPR039780]", "CCR4-NOT transcription complex subunit 7 [IPR039636]", "CCR4-NOT transcription complex subunit 7/8/Pop2 [IPR039637]", "CCR4-NOT transcription complex subunit 9 [IPR007216]", "CD166 antigen [IPR039810]", "CD2 antigen cytoplasmic tail-binding protein 2/Lin1 [IPR039905]", "CD2-associated protein [IPR028445]", "CD36 family [IPR002159]", "CD36/scavenger receptor class B member 1 [IPR005428]", "CDC45 family [IPR003874]", "CDC50/LEM3 family [IPR005045]", "CDGSH iron-sulfur domain-containing protein 1/2 [IPR045131]", "CDK5 regulatory subunit-associated protein 3 [IPR008491]", "CDP-alcohol phosphatidyltransferase [IPR000462]", "CDP-diacylglycerol-inositol 3-phosphatidyltransferase, eukaryote [IPR014387]", "CEBPZ/Mak21-like [IPR040155]", "CGI121/TPRKB [IPR013926]", "CHORD domain containing protein [IPR039790]", "CLIP-associating protein 1 [IPR028399]", "CLU domain containing protein [IPR027523]", "COMM domain-containing protein 2 [IPR037354]", "COMPASS component Swd2/WDR82 [IPR037867]", "COP9 Signalosome complex subunit 7A [IPR037757]", "COP9 signalosome complex subunit 1 [IPR033008]", "COP9 signalosome complex subunit 2 [IPR037750]", "COP9 signalosome complex subunit 3 [IPR037753]", "COP9 signalosome complex subunit 4 [IPR037754]", "COP9 signalosome complex subunit 5 [IPR037740]", "COP9 signalosome complex subunit 7B [IPR027530]", "COP9 signalosome subunit 6 [IPR033859]", "COP9 signalosome, subunit CSN8 [IPR033205]", "COPII coat assembly protein, Sec16 [IPR024880]", "COX15/CtaA family [IPR003780]", "CPI-17 [IPR008025]", "CPSF6/7 family [IPR034772]", "CTP synthase [IPR004468]", "CWF11 family [IPR026300]", "CXXC motif containing zinc binding protein, eukaryotic [IPR008584]", "CYFIP-related Rac1 interactor [IPR039789]", "Cadherin [IPR039808]", "Calcium homeostasis endoplasmic reticulum protein [IPR039037]", "Calcium load-activated calcium channel [IPR008559]", "Calcium uptake protein 1/2/3 [IPR039800]", "Calcium-binding mitochondrial carrier protein Aralar2 [IPR029658]", "Calcium-binding protein CAB45 [IPR027240]", "Calcium-transporting ATPase type 2C member 1 [IPR030336]", "Caldesmon [IPR006017]", "Caldesmon/lymphocyte specific protein [IPR006018]", "Calmodulin-regulated spectrin-associated protein [IPR032940]", "Calpain small subunit 1 [IPR029642]", "Calpain-1 [IPR029643]", "Calpain-2 [IPR029539]", "Calpastatin [IPR026998]", "Calponin/LIMCH1 [IPR001997]", "Calreticulin [IPR009169]", "Calreticulin/calnexin [IPR001580]", "Calsyntenin [IPR026914]", "Calumenin [IPR027239]", "Cap-specific mRNA (nucleoside-2-O-)-methyltransferase 1 [IPR030376]", "Caprin [IPR028816]", "Carbamoyl-phosphate synthase, large subunit [IPR006275]", "Carbamoyl-phosphate synthase, small subunit [IPR006274]", "Carbohydrate sulfotransferase 8-10 [IPR018011]", "Cartilage-associated protein [IPR033212]", "Casein Kinase 2, subunit alpha [IPR045216]", "Casein kinase II, regulatory subunit [IPR000704]", "Cat eye syndrome critical region protein 5 [IPR029621]", "Catechol O-methyltransferase, eukaryotic [IPR017128]", "Catenin delta-1 [IPR028439]", "Cation efflux protein [IPR002524]", "Cation-dependent mannose-6-phosphate receptor [IPR000296]", "Cationic amino acid transport permease [IPR004755]", "Ccdc97-like [IPR018613]", "Cdc37 [IPR004918]", "Cdc42 [IPR037874]", "Cdc73/Parafibromin [IPR007852]", "Cell cycle and apoptosis regulator protein 2 [IPR028811]", "Cell cycle and apoptosis regulator protein [IPR025224]", "Cell cycle control protein 50A [IPR030351]", "Cell division cycle protein 123 [IPR009772]", "Cell division protein borealin [IPR018867]", "Cell growth-regulating nucleolar protein [IPR039999]", "Cell-cycle alteration and expression-elevated protein in tumour [IPR032337]", "Centrin 2 [IPR037629]", "Centromere protein Cenp-K [IPR020993]", "Centromere protein H [IPR040034]", "Centromere protein P [IPR027801]", "Centromere protein U [IPR025214]", "Centrosomal protein of 131kDa [IPR030465]", "Centrosomal protein of 170kDa [IPR026644]", "Centrosomal protein of 290kDa [IPR026201]", "Centrosomal protein of 44kDa [IPR033603]", "Ceramide glucosyltransferase [IPR025993]", "Ceroid-lipofuscinosis neuronal protein 5 [IPR026138]", "Ceroid-lipofuscinosis neuronal protein 6 [IPR029255]", "Cgr1-like [IPR005579]", "Chaperone DnaJ [IPR012724]", "Chaperone DnaK [IPR012725]", "Chaperone tailless complex polypeptide 1 (TCP-1) [IPR017998]", "Chaperonin Cpn60/GroEL [IPR001844]", "Chaperonin Cpn60/GroEL/TCP-1 family [IPR002423]", "Charged multivesicular body protein 1a [IPR029888]", "Chitobiosyldiphosphodolichol beta-mannosyltransferase ALG1-like [IPR026051]", "Chloride channel CLIC-like [IPR009231]", "Chloride channel ClC-3 [IPR002245]", "Chloride channel ClC-6 [IPR002248]", "Chloride channel ClC-7 [IPR002249]", "Chloride channel, voltage gated [IPR001807]", "Chloride intracellular channel protein 1 [IPR030259]", "Chloride intracellular channel protein 4/6 [IPR030257]", "Choline/ethanolamine phosphotransferase [IPR014472]", "Chondroitin N-acetylgalactosaminyltransferase [IPR008428]", "Chromatid cohesion factor MAU2 [IPR019440]", "Chromatin assembly factor 1 subunit A [IPR022043]", "Chromatin assembly factor 1 subunit Cac2/CHAF1B/FAS2 [IPR045145]", "Chromatin complexes subunit BAP18 [IPR037931]", "Chromatin modification-related protein Eaf6 [IPR015418]", "Chromatin-remodeling complex component Sfh1/SNF5 [IPR017393]", "Chromobox protein homologue 3 [IPR038033]", "Chromodomain-helicase-DNA-binding protein 1-like [IPR031053]", "Chromodomain-helicase-DNA-binding protein 8 [IPR034724]", "Chromosome alignment-maintaining phosphoprotein 1 [IPR039330]", "Cilia- and flagella-associated protein 20/CFAP20DC [IPR040441]", "Cip1-interacting zinc finger protein [IPR026811]", "Citrate synthase [IPR002020]", "Citrate synthase, eukaryotic-type [IPR010109]", "Class I-like SAM-dependent O-methyltransferase [IPR002935]", "Clathrin adaptor, mu subunit [IPR001392]", "Clathrin coat assembly protein AP180-like [IPR045192]", "Clathrin interactor 1 [IPR030544]", "Clathrin light chain [IPR000996]", "Clathrin, heavy chain [IPR016341]", "Cleavage and polyadenylation specificity factor subunit 2 [IPR027075]", "Cleavage and polyadenylation specificity factor subunit 6 [IPR034769]", "Cleavage and polyadenylation specificity factor subunit 7 [IPR034770]", "Cleavage stimulation factor subunit 1-like [IPR044633]", "Cleavage stimulation factor subunit 2 [IPR033105]", "Cleavage/polyadenylation specificity factor subunit 5 [IPR016706]", "Cleft lip and palate transmembrane 1 [IPR008429]", "Cleft lip and palate transmembrane protein 1-like protein [IPR030434]", "Clp protease proteolytic subunit /Translocation-enhancing protein TepA [IPR023562]", "Clp protease, ATP-binding subunit ClpX [IPR004487]", "ClpA/B family [IPR001270]", "Clusterin [IPR016016]", "Clusterin-like [IPR000753]", "Co-chaperone protein p23-like [IPR045250]", "Coactosin-like protein [IPR030502]", "Coatomer alpha subunit [IPR016391]", "Coatomer beta subunit (COPB1) [IPR016460]", "Coatomer beta' subunit (COPB2) [IPR016453]", "Coatomer delta subunit [IPR027059]", "Coatomer gamma subunit [IPR017106]", "Coatomer subunit zeta [IPR039652]", "Coatomer, epsilon subunit [IPR006822]", "Cobalamin-dependent methionine synthase [IPR011822]", "Coenzyme A transferase family I [IPR004165]", "Cofactor of BRCA1 [IPR010405]", "Cofilin 1 [IPR027234]", "Cohesin subunit Scc3/SA [IPR039662]", "Coiled-coil and C2 domain-containing protein 1 [IPR039725]", "Coiled-coil domain-containing protein 124/Oxs1 [IPR010422]", "Coiled-coil domain-containing protein 127 [IPR034607]", "Coiled-coil domain-containing protein 134 [IPR026321]", "Coiled-coil domain-containing protein 137 [IPR026680]", "Coiled-coil domain-containing protein 138 [IPR038798]", "Coiled-coil domain-containing protein 22 [IPR008530]", "Coiled-coil domain-containing protein 43 [IPR037666]", "Coiled-coil domain-containing protein 51 [IPR037660]", "Coiled-coil domain-containing protein 86 [IPR026570]", "Coiled-coil domain-containing protein 93 [IPR039116]", "Coiled-coil domain-containing protein R3HC1/R3HCL [IPR039884]", "Coilin [IPR024822]", "Condensin complex subunit 2/barren [IPR022816]", "Condensin complex subunit 3 [IPR027165]", "Condensin subunit 1 [IPR007673]", "Condensin subunit 1/Condensin-2 complex subunit D3 [IPR026971]", "Condensin-2 complex subunit D3 [IPR012371]", "Condensin-2 complex subunit G2 [IPR024741]", "Conserved oligomeric Golgi complex subunit 5 [IPR019465]", "Conserved oligomeric Golgi complex subunit 6 [IPR010490]", "Conserved oligomeric Golgi complex subunit 7 [IPR019335]", "Conserved oligomeric Golgi complex subunit 8 [IPR007255]", "Conserved oligomeric Golgi complex subunit 8, Metazoal and Viridiplantae [IPR016632]", "Conserved oligomeric Golgi complex, subunit 3 [IPR007265]", "Constitutive coactivator of PPAR-gamma [IPR026784]", "Copine [IPR045052]", "Copper chaperone SCO1/SenC [IPR003782]", "Coproporphyrinogen III oxidase, aerobic [IPR001260]", "Core histone macro-H2A [IPR021171]", "Coronin 1B [IPR027340]", "Coronin 1C [IPR027333]", "Coronin 7 [IPR027331]", "Coronin [IPR015505]", "Cortactin [IPR015503]", "Csn12 family [IPR045114]", "Cullin [IPR045093]", "Cullin-4B [IPR033044]", "Cullin-associated NEDD8-dissociated protein 1/2 [IPR039852]", "Cwf19-like protein [IPR040194]", "Cyclic nucleotide phosphodiesterase [IPR008431]", "Cyclin-dependent kinase 6 [IPR028788]", "Cyclophilin-RNA interacting protein [IPR035542]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase [IPR024936]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, cyclophilin A-like [IPR044666]", "Cys/Met metabolism, pyridoxal phosphate-dependent enzyme [IPR000277]", "Cysteine desulfurase IscS [IPR010240]", "Cysteine desulfurase [IPR016454]", "Cysteine oxygenase/2-aminoethanethiol dioxygenase [IPR012864]", "Cysteine protease ATG4B, metazoa [IPR032916]", "Cysteine-tRNA ligase [IPR015803]", "Cysteinyl-tRNA synthetase/mycothiol ligase [IPR024909]", "Cystinyl aminopeptidase [IPR034017]", "Cytochrome B561-related [IPR019176]", "Cytochrome P450 [IPR001128]", "Cytochrome P450, E-class, group I [IPR002401]", "Cytochrome P450, E-class, group IV [IPR002403]", "Cytochrome b-c1 complex subunit 7 [IPR003197]", "Cytochrome b-c1 complex subunit 8 [IPR004205]", "Cytochrome b-c1 complex subunit 9 [IPR008027]", "Cytochrome c oxidase assembly factor 3, mitochondrial [IPR041752]", "Cytochrome c oxidase assembly protein COX14 [IPR029208]", "Cytochrome c oxidase subunit 6C [IPR004204]", "Cytochrome c oxidase subunit I [IPR000883]", "Cytochrome c oxidase subunit IV [IPR013288]", "Cytochrome c oxidase subunit IV family [IPR004203]", "Cytochrome c oxidase subunit VII [IPR039297]", "Cytochrome c oxidase subunit VIIa, metazoa [IPR003177]", "Cytochrome c oxidase subunit VIIa-related, mitochondrial [IPR017267]", "Cytochrome c oxidase subunit VIIc [IPR004202]", "Cytochrome c oxidase, subunit Va/VI [IPR003204]", "Cytochrome c oxidase, subunit Vb [IPR002124]", "Cytochrome c/quinol oxidase subunit II [IPR045187]", "Cytochrome c1 [IPR002326]", "Cytoplasmic FMR1-interacting [IPR008081]", "Cytoplasmic dynein 1 intermediate chain 1/2 [IPR025956]", "Cytoplasmic dynein 2 heavy chain 1 [IPR026815]", "Cytoplasmic protein NCK [IPR017304]", "Cytoplasmic protein NCK1 [IPR028526]", "Cytoplasmic tRNA 2-thiolation protein 2 [IPR019407]", "Cytoskeleton-associated protein 2 family [IPR026165]", "Cytoskeleton-associated protein 4 [IPR028428]", "Cytosolic Fe-S cluster assembly factor NUBP2/Cfd1, eukaryotes [IPR028600]", "Cytosolic acyl coenzyme A thioester hydrolase [IPR040170]", "Cytosolic nonspecific dipeptidase/DUG1 [IPR017153]", "D-3-phosphoglycerate dehydrogenase [IPR006236]", "DAD/Ost2 [IPR003038]", "DDB1- and CUL4-associated factor 8-like [IPR045151]", "DDRGK domain containing protein [IPR019153]", "DDX54/DBP10 family [IPR033517]", "DENR family, eukaryotes [IPR005873]", "DET1- and DDB1-associated protein 1 [IPR033575]", "DNA (cytosine-5)-methyltransferase 1-like [IPR017198]", "DNA damage-binding protein 1 [IPR031297]", "DNA double-strand break repair protein Mre11 [IPR003701]", "DNA fragmentation factor 45 [IPR017299]", "DNA helicase, ATP-dependent, RecQ type [IPR004589]", "DNA ligase, ATP-dependent [IPR000977]", "DNA mismatch repair Msh2-type [IPR011184]", "DNA mismatch repair MutS family [IPR045076]", "DNA mismatch repair protein Msh2 [IPR032642]", "DNA mismatch repair protein MutL/Mlh/Pms [IPR038973]", "DNA mismatch repair protein MutS/MSH [IPR017261]", "DNA polymerase V/Myb-binding protein 1A [IPR007015]", "DNA polymerase alpha, subunit B [IPR016722]", "DNA polymerase delta/II small subunit family [IPR024826]", "DNA polymerase epsilon catalytic subunit [IPR029703]", "DNA polymerase epsilon, subunit B [IPR016266]", "DNA primase large subunit, eukaryotic/archaeal [IPR007238]", "DNA primase, large subunit, eukaryotic [IPR016558]", "DNA primase, small subunit [IPR002755]", "DNA primase, small subunit, eukaryotic/archaeal [IPR014052]", "DNA repair protein Rad50, eukaryotes [IPR004584]", "DNA repair/transcription protein MET18/MMS19 [IPR039920]", "DNA replication complex GINS protein Psf2 [IPR007257]", "DNA replication licensing factor Mcm2 [IPR008045]", "DNA replication licensing factor Mcm3 [IPR008046]", "DNA replication licensing factor Mcm5 [IPR008048]", "DNA replication licensing factor Mcm6 [IPR008049]", "DNA replication licensing factor Mcm7 [IPR008050]", "DNA topoisomerase I [IPR001631]", "DNA topoisomerase II, eukaryotic-type [IPR001154]", "DNA topoisomerase II-beta [IPR028467]", "DNA topoisomerase, type IIA [IPR001241]", "DNA-directed DNA polymerase, family B [IPR006172]", "DNA-directed DNA-polymerase, family A, mitochondria [IPR002297]", "DNA-directed RNA pol I, largest subunit [IPR015699]", "DNA-directed RNA polymerase II subunit Rpb4-like [IPR045222]", "DNA-directed RNA polymerase III subunit RPC3 [IPR039748]", "DNA-directed RNA polymerase III subunit Rpc5 [IPR006886]", "DNA-directed RNA polymerase subunit RPABC5/Rpb10 [IPR000268]", "DNA-directed RNA polymerase subunit Rpo5/Rpb5 [IPR014381]", "DNA-directed RNA polymerase, phage-type [IPR002092]", "DNA-directed RNA polymerase, subunit 2 [IPR015712]", "DNA-directed RNA polymerase, subunit beta-prime [IPR045867]", "DNA-directed RNA polymerases I and III subunit AC40 [IPR033901]", "DNA2/NAM7-like helicase [IPR045055]", "DPM1-like [IPR039528]", "DUF5568 family [IPR040419]", "Daxx protein [IPR005012]", "Death-inducer obliterator 1 [IPR033082]", "Dedicator of cytokinesis [IPR026791]", "Defective-in-cullin neddylation protein [IPR014764]", "Dehydrogenase/reductase SDR member 4-like [IPR029511]", "Delta l-pyrroline-5-carboxylate synthetase [IPR005766]", "Delta(24)-sterol reductase [IPR040165]", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase Ech1-like [IPR045002]", "Delta-1-pyrroline-5-carboxylate dehydrogenase [IPR005931]", "Deoxyhypusine hydroxylase [IPR027517]", "Deoxyhypusine synthase [IPR002773]", "Deoxynucleoside kinase [IPR002624]", "Deoxyuridine triphosphate nucleotidohydrolase [IPR008181]", "Dephospho-CoA kinase [IPR001977]", "Derlin [IPR007599]", "Dermcidin [IPR028130]", "Dermcidin/Lacritin [IPR043557]", "Desmoglein [IPR009123]", "Desmoplakin [IPR028462]", "Desmosomal cadherin [IPR009122]", "Destrin [IPR029924]", "Deubiquitinating enzyme MINDY-3/4 [IPR039785]", "Developmentally regulated GTP-binding protein [IPR045001]", "Dihydrofolate reductase [IPR012259]", "Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component [IPR045257]", "Dihydrolipoamide dehydrogenase [IPR006258]", "Dihydrolipoamide succinyltransferase [IPR006255]", "Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex [IPR006257]", "Dihydropyrimidinase-related protein 2 [IPR030615]", "Dihydropyrimidinase-related protein 5 [IPR030626]", "Dihydroxyacetone kinase [IPR012734]", "Dihydroxyacetone phosphate acyltransferase [IPR028353]", "Dimethylallyltransferase [IPR039657]", "Dipeptidyl-peptidase 3 [IPR005317]", "Diphosphomevalonate decarboxylase [IPR029765]", "Diphosphomevalonate/phosphomevalonate decarboxylase [IPR005935]", "Diphthamide synthesis DHP2 [IPR010014]", "Diphthamide synthesis DPH1/DPH2 [IPR016435]", "Diphthine synthase [IPR004551]", "Dishevelled family [IPR008339]", "Dishevelled-2 [IPR008341]", "Dishevelled-related protein [IPR015506]", "Disks large 1-like [IPR016313]", "Divalent ion tolerance protein, CutA [IPR004323]", "Divergent protein kinase domain 2A/B [IPR020519]", "DnaJ homolog subfamily A member 1/2-like [IPR044713]", "DnaJ homolog subfamily C member 8 [IPR042858]", "DnaJ homologue subfamily C member 10 [IPR021170]", "DnaJ homologue subfamily C, GRV2/DNAJC13 [IPR044978]", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase [IPR039485]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48kDa subunit [IPR005013]", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit Swp1 [IPR008814]", "Dolichyldiphosphatase 1 [IPR039666]", "DoxX family [IPR032808]", "Drebrin [IPR028438]", "Drebrin-like protein [IPR029923]", "Dual specificity protein phosphatase 12 [IPR016278]", "Dymeclin [IPR019142]", "Dynactin subunit 3 [IPR009991]", "Dynactin subunit 4 [IPR008603]", "Dynamin [IPR022812]", "Dynamin-1-like protein [IPR030556]", "Dynamin-2 [IPR027188]", "Dynamin-like 120kDa protein, mitochondrial [IPR033047]", "Dynamitin [IPR028133]", "Dynein 1 light intermediate chain [IPR008467]", "Dynein family light intermediate chain [IPR022780]", "Dynein heavy chain [IPR026983]", "Dynein light chain, type 1/2 [IPR001372]", "Dynein regulator LIS1 [IPR017252]", "Dyslexia-associated protein KIAA0319-like [IPR029865]", "Dystrophin/utrophin [IPR035436]", "E3 SUMO-protein ligase PIAS2 [IPR027228]", "E3 UFM1-protein ligase 1 [IPR018611]", "E3 ubiquitin ligase Bre1 [IPR013956]", "E3 ubiquitin ligase RBR family [IPR031127]", "E3 ubiquitin ligase UBR4-like [IPR045189]", "E3 ubiquitin-protein ligase ARIH2 [IPR031126]", "E3 ubiquitin-protein ligase CHIP/LubX [IPR045200]", "E3 ubiquitin-protein ligase HECTD1/TRIP12-like [IPR045322]", "E3 ubiquitin-protein ligase HECTD3 [IPR042469]", "E3 ubiquitin-protein ligase Praja-2 [IPR030639]", "E3 ubiquitin-protein ligase RBBP6 family [IPR033489]", "E3 ubiquitin-protein ligase RING1/RING2 [IPR043540]", "E3 ubiquitin-protein ligase RING2 [IPR037937]", "E3 ubiquitin-protein ligase RNF14 [IPR031128]", "E3 ubiquitin-protein ligase RNF213 [IPR031248]", "E3 ubiquitin-protein ligase UBR7 [IPR040204]", "E3 ubiquitin-protein ligase ZNF598/Hel2 [IPR044288]", "E3 ubiquitin-protein ligase listerin [IPR039795]", "E3 ubiquitin-protein ligase, SMURF1 type [IPR024928]", "EB1, Metazoa [IPR027739]", "EB2, vertebrate [IPR027735]", "ECSIT [IPR010418]", "EF-hand calcium-binding domain-containing protein 14 [IPR042352]", "EF-hand domain-containing protein D1/2 [IPR040365]", "EH domain-binding protein 1 [IPR029944]", "EH domain-containing protein 1/3 [IPR029951]", "EH domain-containing protein 4 [IPR029952]", "ELL/occludin family [IPR031176]", "ELMO domain-containing protein 2 [IPR030724]", "ELP3/YhcC [IPR039661]", "ER lumen protein retaining receptor [IPR000133]", "ER membrane protein complex subunit 1 [IPR026895]", "ER membrane protein complex subunit 2-like [IPR039856]", "ER membrane protein complex subunit 3 [IPR008568]", "ER membrane protein complex subunit 7 [IPR039163]", "ER membrane protein complex subunit 8/9 [IPR005366]", "ERAP2 aminopeptidase [IPR033528]", "ERG2/sigma1 receptor-like [IPR006716]", "ERp19 [IPR037462]", "ESCRT-II complex, Vps25 subunit [IPR008570]", "ETS family [IPR046328]", "Ecd family [IPR010770]", "Electron transfer flavoprotein alpha subunit/FixB [IPR001308]", "Electron transfer flavoprotein, beta subunit [IPR012255]", "Electron transfer flavoprotein-ubiquinone oxidoreductase [IPR040156]", "Elongation factor 4 [IPR006297]", "Elongation factor G1-like [IPR045044]", "Elongator complex protein 1 [IPR006849]", "Elongator complex protein 2 [IPR037289]", "Elongator complex protein 3-like [IPR034687]", "Elongator complex protein 4 [IPR008728]", "Elongin B [IPR039049]", "Elongin-C [IPR039948]", "Emerin [IPR035004]", "Endonuclease III-like protein 1 [IPR030841]", "Endonuclease domain-containing 1 protein [IPR039015]", "Endophilin-A [IPR028501]", "Endophilin-B1 [IPR028503]", "Endoplasmic reticulum aninopeptidase 1 [IPR033520]", "Endoplasmic reticulum oxidoreductin 1 [IPR007266]", "Endoplasmic reticulum protein SC65 [IPR033213]", "Endoplasmic reticulum resident protein 29 [IPR016855]", "Endoplasmic reticulum vesicle transporter [IPR045888]", "Endosome-associated-trafficking regulator 1 [IPR026757]", "Endothelial protein C receptor [IPR015669]", "Endothelin-converting enzyme 1 [IPR029734]", "Engulfment and cell motility protein 2 [IPR030713]", "Enhancer of mRNA-decapping protein 4-like [IPR045152]", "Enhancer of rudimentary [IPR000781]", "Enolase [IPR000941]", "Enoyl-CoA hydratase/isomerase [IPR001753]", "Enoyl-CoA hydratase/isomerase, HIBYL-CoA-H type [IPR032259]", "Ependymin [IPR001299]", "Ephrin receptor type-A /type-B [IPR016257]", "Epimerase family protein SDR39U1 [IPR010099]", "Epoxide hydrolase [IPR016292]", "Epoxide hydrolase-like [IPR000639]", "Equilibrative nucleoside transporter 1 [IPR030195]", "Equilibrative nucleoside transporter [IPR002259]", "Erbin [IPR032927]", "Ergosterol biosynthesis ERG4/ERG24 [IPR001171]", "Erlin1/2 [IPR033294]", "Essential MCU regulator, mitochondrial [IPR018782]", "Esterase-like [IPR000801]", "Etoposide-induced 2.4 [IPR009890]", "Eukaryotic porin/Tom40 [IPR027246]", "Eukaryotic rRNA processing [IPR008610]", "Eukaryotic translation elongation factor 1 epsilon-1 [IPR042450]", "Eukaryotic translation initiation factor 2D [IPR039757]", "Eukaryotic translation initiation factor 3 subunit A [IPR027512]", "Eukaryotic translation initiation factor 3 subunit B [IPR011400]", "Eukaryotic translation initiation factor 3 subunit D [IPR007783]", "Eukaryotic translation initiation factor 3 subunit E [IPR016650]", "Eukaryotic translation initiation factor 3 subunit F [IPR027531]", "Eukaryotic translation initiation factor 3 subunit G [IPR017334]", "Eukaryotic translation initiation factor 3 subunit H [IPR027524]", "Eukaryotic translation initiation factor 3 subunit I [IPR027525]", "Eukaryotic translation initiation factor 3 subunit J [IPR013906]", "Eukaryotic translation initiation factor 3 subunit K [IPR009374]", "Eukaryotic translation initiation factor 3 subunit M [IPR027528]", "Eukaryotic translation initiation factor 3 subunit M eIF3m/COP9 signalosome complex subunit 7 COPS7 [IPR045237]", "Eukaryotic translation initiation factor 4 gamma 1 [IPR037584]", "Eukaryotic translation initiation factor 4 gamma 3 [IPR037585]", "Eukaryotic translation initiation factor 4B [IPR033107]", "Exocyst complex component EXOC2/Sec5 [IPR029175]", "Exocyst complex component EXOC3/Sec6 [IPR010326]", "Exocyst complex component EXOC5/Sec10 [IPR033960]", "Exocyst complex component EXOC6/Sec15 [IPR007225]", "Exocyst complex component Exo70 [IPR004140]", "Exocyst complex component Exo84 [IPR033961]", "Exocyst complex component Sec10-like [IPR009976]", "Exocyst complex component Sec8/EXOC4 [IPR039682]", "Exonuclease 1 [IPR032641]", "Exosome complex RNA-binding protein 1/RRP40/RRP4 [IPR026699]", "Exosome complex component Csl4 [IPR039771]", "Exosome complex component RRP45 [IPR033100]", "Exosome complex component Rrp43 [IPR033196]", "Exosome complex exonuclease Rrp6-like [IPR045092]", "Exostosin-2 [IPR027673]", "Exostosin-like [IPR004263]", "Exportin 4/7-like [IPR044189]", "Exportin-1/5 [IPR045065]", "Exportin-5 [IPR040018]", "Exportin-7 [IPR040021]", "Exportin-T [IPR040017]", "Ezrin/radixin/moesin [IPR011174]", "Ezrin/radixin/moesin-like [IPR000798]", "F-actin-capping protein subunit alpha [IPR002189]", "F-actin-capping protein subunit beta [IPR001698]", "F-box-like/WD repeat-containing protein Ebi-like [IPR045183]", "FACT complex subunit Spt16 [IPR040258]", "FAD synthetase with the MoaB/Mog domain [IPR012183]", "FAD-dependent glycerol-3-phosphate dehydrogenase [IPR000447]", "FAD-dependent oxidoreductase SdhA/FrdA/AprA [IPR030664]", "FAM175 family [IPR023238]", "FAM175 family, BRISC complex, Abro1 subunit [IPR023240]", "FAM177 family [IPR028260]", "FAM3 family [IPR039220]", "FAM91 [IPR039199]", "FAM98 [IPR018797]", "FH1/FH2 domain-containing protein 1 [IPR027647]", "FHF complex subunit HOOK interacting protein [IPR019384]", "FUN14 [IPR007014]", "Fanconi anemia group G protein [IPR039684]", "Fanconi anemia group I protein [IPR026171]", "Far11/STRP [IPR040185]", "Fascin [IPR010431]", "Fascin, metazoans [IPR024703]", "Fascin-1 [IPR030146]", "Fatty acid desaturase [IPR012171]", "Fatty acid oxidation complex, alpha subunit, mitochondrial [IPR012803]", "Fatty acid transport protein 4 [IPR030304]", "Fatty acyl-CoA reductase [IPR026055]", "Fcf2/DNTTIP2 [IPR039883]", "Ferredoxin-NADP+ reductase, adrenodoxin-type [IPR021163]", "Ferrochelatase [IPR001015]", "Fibrillarin [IPR000692]", "Filamin family [IPR044801]", "Filamin-B [IPR029874]", "Fimbrin/Plastin [IPR039959]", "Flagellum site-determining protein YlxH/ Fe-S cluster assembling factor NBP35 [IPR033756]", "Flap endonuclease 1 [IPR023426]", "Flotillin family [IPR027705]", "Formate-tetrahydrofolate ligase, FTHFS [IPR000559]", "Formin, protein diaphanous homologue 1 [IPR027653]", "Formin, protein diaphanous homologue 3 [IPR027654]", "Formin-binding protein 1 [IPR028532]", "Four and a half LIM domains protein 1 [IPR042997]", "Fragile X mental retardation syndrome-related protein [IPR040148]", "Fructosamine/Ketosamine-3-kinase [IPR016477]", "Fructose-bisphosphate aldolase, class-I [IPR000741]", "Fumarate hydratase, class II [IPR005677]", "Fumarate lyase family [IPR000362]", "Fumarylacetoacetase [IPR005959]", "Fyv10 family [IPR045098]", "G patch domain-containing protein 11 [IPR039249]", "G-protein alpha subunit, group 12/13 [IPR000469]", "G-protein alpha subunit, group I [IPR001408]", "G-protein alpha subunit, group Q [IPR000654]", "G-protein, gamma subunit [IPR001770]", "G-rich sequence factor 1 [IPR033106]", "G10 protein [IPR001748]", "GDP dissociation inhibitor [IPR018203]", "GDP-L-fucose synthase/GDP-L-colitose synthase [IPR028614]", "GDP-fucose protein O-fucosyltransferase 1 [IPR039922]", "GDP-fucose protein O-fucosyltransferase 2-like [IPR045130]", "GDP-fucose protein O-fucosyltransferase [IPR019378]", "GDP-mannose 4,6-dehydratase [IPR006368]", "GH3 family [IPR004993]", "GINS complex subunit Sld5 [IPR008591]", "GINS complex, subunit Psf3 [IPR010492]", "GOLM1/CASC4 family [IPR026139]", "GOSR2/Membrin/Bos1 [IPR027027]", "GPCR-associated sorting protein [IPR043374]", "GPI ethanolamine phosphate transferase 2 [IPR039527]", "GPI mannosyltransferase [IPR005599]", "GPI transamidase component Gaa1 [IPR007246]", "GPI transamidase component PIG-T [IPR007245]", "GPI-anchor transamidase [IPR028361]", "GPN-loop GTPase 1 [IPR030230]", "GPN-loop GTPase [IPR004130]", "GRASP55/65 [IPR007583]", "GRIM-19 [IPR009346]", "GTP cyclohydrolase 1 type 2/Nif3 [IPR002678]", "GTP-binding protein 1 [IPR039263]", "GTP-binding protein Era [IPR005662]", "GTP-binding protein Obg/CgtA [IPR014100]", "GTP-binding protein Rheb [IPR037586]", "GTP-binding protein, ribosome biogenesis [IPR019991]", "GTP-binding protein, ribosome biogenesis, YsxC [IPR019987]", "GTPase, MTG1 [IPR016478]", "Galactokinase [IPR000705]", "Galanin precursor [IPR008175]", "Galectin-3 [IPR015534]", "Galectin-like [IPR044156]", "Gamma tubulin [IPR002454]", "Gamma-adducin [IPR027772]", "Gamma-glutamylcyclotransferase [IPR017939]", "Gamma-tubulin complex component protein [IPR007259]", "Ganglioside GM2 activator [IPR028996]", "Gdt1 family [IPR001727]", "Gem-associated protein 4 [IPR033265]", "Gemini of Cajal bodies-associated protein 8 [IPR034754]", "General transcription factor 3C polypeptide 4 [IPR044230]", "Geranylgeranyl transferase type-2 subunit alpha [IPR032955]", "Geranylgeranyl transferase type-2 subunit beta [IPR026873]", "Glia maturation factor [IPR011171]", "Glomulin/ALF4 [IPR019516]", "Glucosamine-6-phosphate isomerase [IPR004547]", "Glucosamine-fructose-6-phosphate aminotransferase, isomerising [IPR005855]", "Glucose transporter GLUT [IPR045263]", "Glucose transporter, type 1 (GLUT1) [IPR002439]", "Glucose-6-phosphate dehydrogenase [IPR001282]", "Glucosidase II beta subunit-like [IPR039794]", "Glutamate 5-kinase/delta-1-pyrroline-5-carboxylate synthase [IPR005715]", "Glutamate carboxypeptidase 2-like [IPR039373]", "Glutamate--cysteine ligase regulatory subunit [IPR032963]", "Glutamate-cysteine ligase catalytic subunit [IPR004308]", "Glutamate-rich protein 1 [IPR026719]", "Glutamate-tRNA ligase, bacterial/mitochondrial [IPR004527]", "Glutamate/acetylglutamate kinase [IPR001057]", "Glutaminase [IPR015868]", "Glutamine-dependent NAD(+) synthetase [IPR014445]", "Glutamine-tRNA synthetase [IPR004514]", "Glutamyl-tRNA synthetase, archaeal/eukaryotic cytosolic [IPR004526]", "Glutamyl-tRNA(Gln) amidotransferase A subunit [IPR004412]", "Glutamyl/glutaminyl-tRNA synthetase [IPR000924]", "Glutathione S-transferase Omega/Tau-like [IPR045073]", "Glutathione S-transferase kappa [IPR044088]", "Glutathione S-transferase, Mu class [IPR003081]", "Glutathione S-transferase, alpha class [IPR003080]", "Glutathione S-transferase, omega-class [IPR005442]", "Glutathione S-transferases, class Zeta [IPR005955]", "Glutathione Transferase family [IPR040079]", "Glutathione peroxidase Gpx7, putative [IPR013376]", "Glutathione peroxidase [IPR000889]", "Glutathione reductase, eukaryote/bacterial [IPR006322]", "Glutathione synthase [IPR005615]", "Glyceraldehyde-3-phosphate dehydrogenase, type I [IPR006424]", "Glyceraldehyde/Erythrose phosphate dehydrogenase family [IPR020831]", "Glycerol-3-phosphate O-acyltransferase/Dihydroxyacetone phosphate acyltransferase [IPR022284]", "Glycerol-3-phosphate acyltransferase, PlsB [IPR028354]", "Glycine cleavage system P protein [IPR020581]", "Glycine dehydrogenase (decarboxylating) [IPR003437]", "Glycogen debranching enzyme [IPR010401]", "Glycogen debranching enzyme, metazoa [IPR006421]", "Glycogen synthase [IPR008631]", "Glycogen synthase kinase-3 beta [IPR033573]", "Glycogen/starch/alpha-glucan phosphorylase [IPR011833]", "Glycoside hydrolase family 30 [IPR001139]", "Glycoside hydrolase family 31 [IPR000322]", "Glycoside hydrolase family 47 [IPR001382]", "Glycoside hydrolase family 63 [IPR004888]", "Glycoside hydrolase, family 2 [IPR006101]", "Glycoside hydrolase, family 27 [IPR002241]", "Glycoside hydrolase, family 29 [IPR000933]", "Glycoside hydrolase, family 35 [IPR001944]", "Glycosyl hydrolase family 99 [IPR026071]", "Glycosyl transferase, family 13 [IPR004139]", "Glycosyl transferase, family 25 [IPR002654]", "Glycosyl transferase, family 31 [IPR002659]", "Glycosyl transferase, family 35 [IPR000811]", "Glycosyl transferase, family 43 [IPR005027]", "Glycosyl transferase, family 8 [IPR002495]", "Glycosyltransferase 61 [IPR007657]", "Glycyl-tRNA synthetase [IPR002315]", "Glycyl-tRNA synthetase/DNA polymerase subunit gamma-2 [IPR027031]", "Glyoxalase I [IPR004361]", "Glyoxalase domain-containing protein 4 [IPR043193]", "Golgi SNAP receptor complex, subunit 1 [IPR023601]", "Golgi apparatus protein 1 [IPR039728]", "Golgi integral membrane protein 4 [IPR042336]", "Golgi membrane protein 1 [IPR026143]", "Golgi phosphoprotein 3-like [IPR008628]", "Golgi to ER traffic protein 4 [IPR007317]", "Golgi-associated PDZ and coiled-coil motif-containing protein [IPR038879]", "Golgin subfamily A [IPR024858]", "Golgin subfamily A member 3 [IPR033288]", "Golgin subfamily A member 5 [IPR019177]", "Golgin subfamily B member 1 [IPR026202]", "Graves disease carrier protein [IPR002167]", "GroES chaperonin family [IPR020818]", "Groucho/transducin-like enhancer [IPR009146]", "Growth arrest/ DNA-damage-inducible protein-interacting protein 1 [IPR018472]", "GrpE nucleotide exchange factor [IPR000740]", "Guanidinoacetate N-methyltransferase [IPR016550]", "Guanine nucleotide binding protein (G-protein), alpha subunit [IPR001019]", "Guanine nucleotide exchange factor, Ric8 [IPR019318]", "Guanine nucleotide-exchange factor Sec12-like [IPR045260]", "H/ACA ribonucleoprotein complex non-core subunit Naf1 [IPR040309]", "H/ACA ribonucleoprotein complex, subunit Gar1/Naf1 [IPR007504]", "H/ACA ribonucleoprotein complex, subunit Nhp2, eukaryote [IPR002415]", "H/ACA ribonucleoprotein complex, subunit Nop10 [IPR007264]", "HAD hydrolase, LHPP/HDHD2 [IPR006355]", "HAD hydrolase, subfamily IA [IPR006439]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like [IPR011949]", "HAD-superfamily hydrolase, subfamily IG, 5'-nucleotidase [IPR008380]", "HAD-superfamily hydrolase, subfamily IIA [IPR006357]", "HAD-superfamily hydrolase, subfamily IIA, CECR5 [IPR006353]", "HAUS augmin-like complex subunit 1 [IPR026243]", "HAUS augmin-like complex subunit 3 [IPR026206]", "HAUS augmin-like complex subunit 4 [IPR029327]", "HAUS augmin-like complex subunit 4, metazoa [IPR026214]", "HAUS augmin-like complex subunit 5 [IPR029131]", "HAUS augmin-like complex subunit 6 [IPR026797]", "HAUS complex subunit 5, metazoa [IPR026215]", "HCCA isomerase/glutathione S-transferase kappa [IPR014440]", "HCLS1-binding protein 3 [IPR039701]", "HEXIM [IPR024872]", "HMG-CoA lyase [IPR043594]", "HS1-associating protein X-1 [IPR017248]", "Haem oxygenase [IPR002051]", "Haem oxygenase-like [IPR016053]", "Haloacid dehalogenase-like hydrolase [IPR041492]", "Ham1-like protein [IPR002637]", "Heat shock 70kDa protein 12A [IPR026685]", "Heat shock 70kDa protein 13 [IPR042048]", "Heat shock protein 70 family [IPR013126]", "Heat shock protein Hsp90 family [IPR001404]", "Heat shock protein Sti1-like [IPR045248]", "Helicase MOV-10 [IPR026122]", "Helicase SMUBP-2/Hcs1-like [IPR004483]", "Helicase XPB/Ssl2 [IPR001161]", "Helicase superfamily 1/2, DinG/Rad3-like [IPR045028]", "Heme A synthase, type 2 [IPR023754]", "Heparan sulphate 2-O-sulfotransferase [IPR007734]", "Heterochromatin protein 1-binding protein 3 [IPR033061]", "Heterogeneous nuclear ribonucleoprotein C [IPR017347]", "Heterogeneous nuclear ribonucleoprotein K [IPR033090]", "Heterogeneous nuclear ribonucleoprotein M [IPR024667]", "Heterogeneous nuclear ribonucleoprotein U [IPR026745]", "Heterogeneous nuclear ribonucleoprotein U-like protein 1 [IPR027025]", "Hexokinase [IPR001312]", "High mobility group protein HMG-I/HMG-Y, chordates [IPR031079]", "High mobility group protein HMGA [IPR000116]", "High mobility group protein HMGB1 [IPR031076]", "High mobility group protein HMGB3 [IPR031077]", "High mobility group protein HMGN [IPR000079]", "Higher eukaryotic phosphomevalonate kinase [IPR005919]", "Histidine phosphatase superfamily, clade-1 [IPR013078]", "Histidine phosphatase superfamily, clade-2 [IPR000560]", "Histidine triad (HIT) protein [IPR001310]", "Histone H2A [IPR002119]", "Histone H3/CENP-A [IPR000164]", "Histone H4 [IPR001951]", "Histone PARylation factor 1 [IPR019361]", "Histone acetyltransferase type B, catalytic subunit [IPR017380]", "Histone acetyltransferases subunit 3 [IPR019340]", "Histone deacetylase [IPR003084]", "Histone deacetylase complex subunit SAP30/SAP30-like [IPR024145]", "Histone deacetylase complex, SAP18 subunit [IPR017250]", "Histone deacetylase family [IPR000286]", "Histone demethylase JHDM2-like [IPR045109]", "Histone lysine-specific demethylase [IPR017366]", "Histone transcription regulator 3/CABIN1 [IPR033053]", "Histone-lysine N-methyltransferase EZH1/2-like [IPR045318]", "Histone-lysine N-methyltransferase EZH1/EZH2 [IPR021654]", "Histone-lysine N-methyltransferase SETD1A [IPR037841]", "Histone-lysine N-methyltransferase SETDB1 [IPR025796]", "Histone-lysine N-methyltransferase Set1-like [IPR044570]", "Histone-lysine N-methyltransferase Smyd3 [IPR025805]", "HnRNP R/Q splicing factor [IPR006535]", "HnRNP-L/PTB [IPR006536]", "Holocytochrome c/c1 synthase [IPR000511]", "Host cell factor 1 [IPR037854]", "Host cell factor [IPR043536]", "Huntingtin-interacting protein 1 [IPR030554]", "Huntingtin-interacting protein 1-related protein [IPR030555]", "Hydantoinase/dihydropyrimidinase [IPR011778]", "Hydroxymethylglutaryl-CoA reductase, class I/II [IPR002202]", "Hydroxymethylglutaryl-CoA reductase, eukaryotic/archaeal type [IPR004554]", "Hydroxymethylglutaryl-CoA reductase, metazoan [IPR004816]", "Hydroxymethylglutaryl-CoA synthase, eukaryotic [IPR010122]", "Hypoxanthine phosphoribosyl transferase [IPR005904]", "Hypoxia-inducible factor 1-alpha inhibitor [IPR027445]", "I-BAR domain containing protein IRSp53 [IPR030128]", "I-BAR domain containing protein IRSp53/IRTKS/Pinkbar [IPR027681]", "ICln [IPR003521]", "IPP transferase [IPR018022]", "IQ calmodulin-binding motif-containing protein 1 [IPR028765]", "Immunity-related GTPase family Q protein [IPR040070]", "Impact family [IPR023582]", "Importin beta family [IPR040122]", "Importin subunit alpha [IPR024931]", "Inhibitor of nuclear factor kappa-B kinase-interacting protein [IPR024152]", "Initiation factor 2B alpha/beta/delta [IPR011559]", "Initiation factor 2B-related [IPR000649]", "Initiation factor 4G [IPR045208]", "Inner centromere protein [IPR039130]", "Inner nuclear membrane protein Man1 [IPR034997]", "Innexin [IPR000990]", "Inorganic pyrophosphatase [IPR008162]", "Inosine triphosphate pyrophosphatase [IPR027502]", "Inosine-5'-monophosphate dehydrogenase [IPR005990]", "Inositol 1,4,5-trisphosphate receptor-interacting protein [IPR024797]", "Inositol 1,4,5-trisphosphate receptor-interacting protein family [IPR026250]", "Inositol 3,4-bisphosphate 4-phosphatase [IPR039034]", "Inositol monophosphatase-like [IPR000760]", "Inositol-tetrakisphosphate 1-kinase [IPR008656]", "Insulin receptor substrate [IPR039011]", "Insulin-like growth factor 2 mRNA-binding protein 2 [IPR028743]", "Integral membrane protein 2 [IPR040145]", "Integral membrane protein EMC3/TMCO1-like [IPR002809]", "Integral membrane protein SYS1 [IPR016973]", "Integral membrane protein SYS1-related [IPR019185]", "Integrator complex subunit 1 [IPR038902]", "Integrator complex subunit 14 [IPR039841]", "Integrator complex subunit 2 [IPR029321]", "Integrator complex subunit 2, metazoa [IPR026236]", "Integrator complex subunit 3 [IPR045334]", "Integrator complex subunit 5 [IPR040316]", "Integrator complex subunit 9 [IPR027074]", "Integrin alpha chain [IPR000413]", "Integrin beta subunit [IPR015812]", "Integrin beta-1 subunit [IPR027071]", "Interferon-induced protein with tetratricopeptide repeat 5 [IPR024125]", "Interferon-inducible double-stranded RNA-dependent protein kinase activator A [IPR033363]", "Interleukin enhancer-binding factor 3 [IPR033099]", "Intermembrane space protein MIX23 [IPR019171]", "Intersectin-2 [IPR027029]", "Intracellular chloride channel [IPR002946]", "Intracellular hyaluronic acid binding protein [IPR026203]", "Intraflagellar transport protein 27 homologue, eukaryotes [IPR034112]", "Intraflagellar transport protein 52 homolog [IPR039975]", "Intron Large complex component GCFC2-like [IPR012890]", "Inverted formin-2 [IPR027649]", "Iron regulatory protein 1 [IPR029784]", "Iron-sulfur protein NUBPL-like [IPR044304]", "Isoamyl acetate-hydrolyzing esterase Iah1-like [IPR045136]", "Isochorismatase domain-containing protein 2 [IPR040318]", "Isocitrate dehydrogenase NAD-dependent [IPR004434]", "Isocitrate dehydrogenase NADP-dependent [IPR004790]", "Isoleucine-tRNA ligase [IPR002301]", "Isoleucine-tRNA ligase, type 1 [IPR023585]", "Isoleucine-tRNA ligase, type 2 [IPR023586]", "Isopentenyl-diphosphate delta-isomerase, type 1 [IPR011876]", "Isoprenylcysteine carboxyl methyltransferase [IPR007269]", "Isovaleryl-CoA dehydrogenase [IPR034183]", "J-protein Zuotin/DnaJC2 [IPR044634]", "JNK-interacting protein 3/4 [IPR039911]", "JmjC domain-containing [IPR039994]", "Junction plakoglobin [IPR030461]", "Junctional adhesion molecule A [IPR042456]", "Junctional adhesion molecule C [IPR042974]", "K/Cl co-transporter 4 [IPR030354]", "K/Cl co-transporter [IPR000076]", "KH domain-containing BBP-like [IPR045071]", "KIF-1 binding protein [IPR022083]", "KIN17-like protein [IPR037321]", "KRR1 interacting protein 1 [IPR018034]", "Katanin p60 subunit A1 [IPR028596]", "Kelch-like ECH-associated protein 1 [IPR030563]", "Keratin, type I [IPR002957]", "Kindlin/fermitin [IPR037843]", "Kinectin [IPR024854]", "Kinesin light chain [IPR002151]", "Kinesin-like protein KIF20A [IPR027326]", "Kinesin-like protein KIF20B [IPR028828]", "Kinesin-like protein KIF22 (Kid) [IPR026986]", "Kinesin-like protein [IPR027640]", "Kinetochore Mis14/Nsl1 [IPR013950]", "Kinetochore-Ndc80 subunit Spc24 [IPR013252]", "Ku70 [IPR006165]", "Ku80 [IPR024193]", "Kynurenine--oxoglutarate transaminase 3 [IPR034612]", "L-lactate dehydrogenase [IPR011304]", "L-lactate/malate dehydrogenase [IPR001557]", "L-type amino acid transporter [IPR004760]", "LAMTOR1/MEH1 [IPR028209]", "LAR-interacting protein, Liprin [IPR029515]", "LEM domain-containing protein 2 [IPR034994]", "LETM1/MDM38-like [IPR044202]", "LIM domain and actin-binding protein 1 [IPR028740]", "LIM domain and actin-binding protein LIMA-like [IPR045268]", "LMBR1-like membrane protein [IPR006876]", "LRP chaperone MESD [IPR019330]", "La domain containing protein [IPR045180]", "LanC-like protein, eukaryotic [IPR020464]", "Lanthionine synthetase C-like [IPR007822]", "Las1 [IPR007174]", "Learning associated protein 18-like [IPR018784]", "Lecithin:cholesterol/phospholipid:diacylglycerol acyltransferase [IPR003386]", "Lethal(2) giant larvae protein [IPR000664]", "Leucine zipper putative tumor suppressor [IPR045329]", "Leucine zipper putative tumour suppressor 2 [IPR028597]", "Leucine zipper transcription factor-like protein 1 [IPR026157]", "Leucine-rich PPR motif-containing protein [IPR033490]", "Leucine-rich repeat protein SHOC2 [IPR027036]", "Leucine-rich repeat-containing 41 [IPR026137]", "Leucine-tRNA ligase [IPR002302]", "Leucyl-tRNA synthetase, class Ia, archaeal/eukaryotic cytosolic [IPR004493]", "Leukocyte elastase inhibitor (serpin B1) [IPR015557]", "Leukocyte surface antigen CD47 [IPR006704]", "Leukotriene A4 hydrolase/leucine aminopeptidase [IPR012777]", "Leukotriene B4 12-hydroxydehydrogenase/15-oxo-prostaglandin 13-reductase [IPR014190]", "LicD family [IPR007074]", "Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3 [IPR027141]", "Linker histone H1/H5 [IPR005819]", "Lipase maturation factor [IPR009613]", "Lipase, eukaryotic [IPR025483]", "Lipid droplet-associated hydrolase [IPR019363]", "Liprin-alpha-1 [IPR030438]", "Lon protease [IPR027065]", "Lon protease homologue 2, peroxisomal [IPR027501]", "Lon protease homologue, chloroplastic/mitochondrial [IPR027503]", "Lon protease, bacterial/eukaryotic-type [IPR004815]", "Long-chain fatty acid CoA synthetase, eukaryotic [IPR045311]", "Low temperature viability protein Ltv1 [IPR007307]", "Luc7-related [IPR004882]", "Lupus La protein [IPR002344]", "LysM and putative peptidoglycan-binding domain-containing protein 1-4 [IPR045030]", "Lysine-tRNA ligase, class II [IPR002313]", "Lysophosphatidylserine lipase ABHD12 [IPR026605]", "Lysosomal thioesterase PPT2 [IPR030295]", "Lysosomal-associated transmembrane protein 4/5 [IPR004687]", "Lysosomal-associated transmembrane protein, 4A/5 [IPR018396]", "Lysosome membrane protein II [IPR005429]", "Lysosome-associated membrane glycoprotein [IPR002000]", "M-phase phosphoprotein 6 [IPR019324]", "MCT-1/Tma20 [IPR016437]", "MCU family [IPR039055]", "MDN2-binding protein [IPR039061]", "MICOS complex subunit MIC19/MIC25 [IPR007964]", "MICOS complex subunit MIC26/MIC27 [IPR019166]", "MICOS complex subunit MIC26/MIC27, animal [IPR033182]", "MICOS complex subunit Mic13 [IPR026769]", "MOB kinase activator family [IPR005301]", "MORF4 family-associated protein 1 [IPR029254]", "MRG [IPR008676]", "MRPS27/PTCD2 [IPR034913]", "Macrophage migration inhibitory factor [IPR001398]", "Mad2-like [IPR045091]", "Magnesium transporter MRS2-like [IPR039204]", "Magnesium transporter protein 1 [IPR006844]", "Major centromere autoantigen B [IPR033062]", "Major facilitator superfamily [IPR011701]", "Major facilitator, sugar transporter-like [IPR005828]", "Mak16 protein [IPR006958]", "Malate dehydrogenase, NAD-dependent, cytosolic [IPR011274]", "Malate dehydrogenase, type 1 [IPR010097]", "Malate dehydrogenase, type 2 [IPR010945]", "Malectin [IPR039155]", "Malic oxidoreductase [IPR001891]", "Manganese/iron superoxide dismutase [IPR001189]", "Mannose-6-phosphate isomerase [IPR016305]", "Mannose-6-phosphate isomerase, type I [IPR001250]", "Mannose-6-phosphate receptor [IPR028927]", "Mannose-P-dolichol utilization defect 1 protein [IPR016817]", "Matrix-remodeling-associated protein 7 [IPR026622]", "Med25/PTOV1 [IPR045105]", "Mediator complex, subunit Med14 [IPR013947]", "Mediator complex, subunit Med17 [IPR019313]", "Mediator complex, subunit Med21 [IPR021384]", "Mediator complex, subunit Med23 [IPR021629]", "Mediator complex, subunit Med24, [IPR021429]", "Mediator complex, subunit Med4 [IPR019258]", "Medium-chain dehydrogenase/reductase [IPR045010]", "Medium-chain specific acyl-CoA dehydrogenase [IPR034180]", "Melanoma-associated antigen D2 [IPR028810]", "Melanoma-associated antigen [IPR037445]", "Membralin [IPR019144]", "Membrane insertase YidC/ALB3/OXA1/COX18 [IPR001708]", "Membrane bound O-acyl transferase, MBOAT [IPR004299]", "Membrane magnesium transporter [IPR018937]", "Membrane-associated, eicosanoid/glutathione metabolism (MAPEG) protein [IPR001129]", "Mesoderm induction early response protein/metastasis-associated protein [IPR040138]", "Metal-dependent protein hydrolase [IPR003226]", "Metastasis-associated protein MTA2 [IPR037964]", "Methionine-tRNA ligase, type 1 [IPR023458]", "Methionine-tRNA synthetase, type 2 [IPR023457]", "Methionyl-tRNA synthetase [IPR014758]", "Methyl-CpG binding protein MeCP2 [IPR017353]", "Methyl-CpG binding protein MeCP2/MBD4 [IPR045138]", "Methyl-CpG-binding domain protein 3 [IPR037965]", "Methylcrotonoyl-CoA carboxylase beta chain MCCB/AccD1-like [IPR045190]", "Methylmalonate-semialdehyde dehydrogenase [IPR010061]", "Methylpurine-DNA glycosylase [IPR003180]", "Methylthioadenosine phosphorylase (MTAP) [IPR010044]", "Methylthioribose-1-phosphate isomerase [IPR005251]", "Methylthiotransferase [IPR005839]", "Methyltransferase Ppm1/Ppm2/Tcmp [IPR007213]", "Mevalonate/galactokinase [IPR006206]", "Mff/Tango-11 [IPR008518]", "MiaB-like tRNA modifying enzyme, archaeal-type [IPR006466]", "Microfibrillar-associated protein 1 [IPR033194]", "Microprocessor complex subunit DGCR8 [IPR040375]", "Microsomal glutathione S-transferase 1-like [IPR040162]", "Microtubule associated protein 1 [IPR026074]", "Microtubule associated protein 1A [IPR015656]", "Microtubule-associated protein 1B [IPR027321]", "Microtubule-associated protein 1S [IPR027322]", "Microtubule-associated protein 4 [IPR027323]", "Microtubule-associated protein 7 family [IPR008604]", "Microtubule-associated protein Jupiter [IPR033335]", "Microtubule-associated protein RP/EB [IPR027328]", "Microtubule-associated protein, MAP65/Ase1/PRC1 [IPR007145]", "Midasin [IPR012099]", "Midline-1 [IPR027727]", "Mini-chromosome maintenance complex protein 4 [IPR008047]", "Mini-chromosome maintenance complex-binding protein [IPR019140]", "Mini-chromosome maintenance protein [IPR031327]", "Mitochondria fission 1 protein [IPR016543]", "Mitochondrial 18kDa protein [IPR019560]", "Mitochondrial 28S ribosomal protein S31 [IPR026299]", "Mitochondrial 28S ribosomal protein S34 [IPR032053]", "Mitochondrial ATP synthase subunit g, animal [IPR016702]", "Mitochondrial ATPase inhibitor [IPR007648]", "Mitochondrial F1-F0 ATP synthase subunit F, predicted [IPR019344]", "Mitochondrial Rho GTPase 1 [IPR029506]", "Mitochondrial Rho GTPase [IPR021181]", "Mitochondrial antiviral-signalling protein, metazoan [IPR026148]", "Mitochondrial carrier UCP-like [IPR002030]", "Mitochondrial carrier protein Mtm1-like [IPR045315]", "Mitochondrial carrier protein [IPR002067]", "Mitochondrial dynamics protein MID49/MID51 [IPR045909]", "Mitochondrial fission regulator 1 [IPR007972]", "Mitochondrial glycoprotein [IPR003428]", "Mitochondrial import inner membrane translocase subunit TIM22 [IPR039175]", "Mitochondrial import inner membrane translocase subunit Tim44 [IPR017303]", "Mitochondrial import inner membrane translocase subunit Tim50 [IPR027111]", "Mitochondrial import inner membrane translocase subunit Tim8/13 [IPR039238]", "Mitochondrial import receptor subunit TOM5, metazoa [IPR029179]", "Mitochondrial import receptor subunit Tom22 [IPR005683]", "Mitochondrial inner membrane protein Mitofilin [IPR019133]", "Mitochondrial inner membrane translocase complex, subunit Tim17 [IPR005678]", "Mitochondrial inner membrane translocase complex, subunit Tim23 [IPR005681]", "Mitochondrial outer membrane translocase complex, subunit Tom5 [IPR019603]", "Mitochondrial phosphate carrier protein Pic2/Mir1-like [IPR044677]", "Mitochondrial processing peptidase subunit beta [IPR037718]", "Mitochondrial pyruvate carrier [IPR005336]", "Mitochondrial ribonuclease P catalytic subunit [IPR033495]", "Mitochondrial ribosomal protein L48 [IPR027487]", "Mitochondrial-processing peptidase subunit alpha [IPR037715]", "Mitofusin family [IPR027094]", "Mitofusin-2 [IPR027089]", "Mitogen-activated protein (MAP) kinase kinase kinase 7 [IPR017421]", "Mitogen-activated protein (MAP) kinase p38-like [IPR008352]", "Mitogen-activated protein (MAP) kinase phosphatase [IPR008343]", "Mitogen-activated protein (MAP) kinase, ERK1/2 [IPR008349]", "Mitogen-activated protein kinase 14 [IPR038784]", "Mitoguardin [IPR019392]", "Mitotic spindle checkpoint protein Bub1/Mad3 [IPR015661]", "Mo25-like [IPR013878]", "Molecular chaperone regulator BAG [IPR039773]", "Molybdate-anion transporter [IPR008509]", "Molybdate-anion transporter, animal type [IPR030163]", "Molybdenum cofactor biosynthesis C [IPR023045]", "Molybdenum cofactor biosynthesis protein A [IPR013483]", "Molybdenum cofactor sulfurase [IPR028886]", "Molybdopterin biosynthesis protein MoeA-like [IPR038987]", "Monocarboxylate transporter 1 [IPR030757]", "Monocarboxylate transporter [IPR004743]", "Monothiol glutaredoxin-related [IPR004480]", "Mortality factor 4-like protein 1 [IPR038011]", "Mortality factor 4-like protein 2 [IPR038012]", "Mpv17/PMP22 [IPR007248]", "Mrp/NBP35 ATP-binding protein [IPR019591]", "Multi drug resistance-associated protein [IPR005292]", "Multidrug resistance protein 1 [IPR030258]", "Multifunctional methyltransferase subunit Trm112 [IPR039127]", "Multiple myeloma tumor-associated protein 2-like [IPR039207]", "Myelin expression factor 2 [IPR034632]", "Myeloid-derived growth factor [IPR018887]", "Myo-inositol-1-phosphate synthase [IPR002587]", "Myristoyl-CoA:protein N-myristoyltransferase [IPR000903]", "Myristoylated alanine-rich C-kinase substrate MARCKS [IPR002101]", "N-acetyl-D-glucosamine kinase NAGK-like [IPR039758]", "N-acetylgalactosamine-6-sulfatase [IPR035626]", "N-acetylglucosamine-6-sulfatase [IPR012251]", "N-acetylglucosamine-6-sulfatase, metazoan [IPR015981]", "N-acetylglucosaminyl phosphatidylinositol deacetylase-related [IPR003737]", "N-acetylglucosaminyl-phosphatidylinositol de-N-acetylase [IPR039516]", "N-acetyltransferase Ard1-like [IPR045047]", "N-alpha-acetyltransferase 40 [IPR039949]", "N-cadherin [IPR030051]", "N-lysine methyltransferase FAM173A/B [IPR026170]", "N-terminal acetyltransferase A, auxiliary subunit [IPR021183]", "NAD kinase 2, mitochondrial [IPR012355]", "NAD kinase [IPR002504]", "NAD(+) synthetase [IPR003694]", "NAD(P) transhydrogenase, alpha subunit [IPR026255]", "NAD(P)H-quinone oxidoreductase subunit D/H [IPR022885]", "NAD/FAD transporter SLC25A32-like [IPR044712]", "NADH dehydrogenase 1, beta subcomplex, subunit 6 [IPR019174]", "NADH dehydrogenase, subunit C [IPR010218]", "NADH ubiquinone oxidoreductase, F subunit [IPR011537]", "NADH-plastoquinone oxidoreductase, chain 5 subgroup [IPR018393]", "NADH-quinone oxidoreductase subunit E-like [IPR002023]", "NADH-quinone oxidoreductase, chain 5-like [IPR003945]", "NADH-quinone oxidoreductase, chain I [IPR010226]", "NADH-ubiquinone oxidoreductase, 20 Kd subunit [IPR006138]", "NADH-ubiquinone oxidoreductase, subunit 10 [IPR019377]", "NADH-ubiquinone reductase complex 1 MLRQ subunit [IPR010530]", "NADH:cytochrome b5 reductase-like [IPR001834]", "NADH:ubiquinone oxidoreductase, ESSS subunit [IPR019329]", "NADH:ubiquinone oxidoreductase, NDUFB5/SGDH subunit [IPR019173]", "NADH:ubiquinone oxidoreductase, subunit 1/F420H2 oxidoreductase subunit H [IPR001694]", "NADH:ubiquinone oxidoreductase, subunit G [IPR010228]", "NADH:ubiquinone oxidoreductase, subunit NDUFB4 [IPR009866]", "NADPH-cytochrome P450 reductase [IPR023208]", "NDRG [IPR004142]", "NDUFAF3/Mth938 domain-containing protein [IPR007523]", "NEDD8 ultimate buster 1 [IPR039749]", "NEDD8-activating enzyme E1 catalytic subunit [IPR030468]", "NEDD8-activating enzyme E1 regulatory subunit APP-BP1 [IPR030667]", "NF-kappa-B inhibitor-like protein 1 [IPR038753]", "NIF3-like protein 1, animal [IPR017222]", "NOL6/Upt22 [IPR005554]", "NPC1-like [IPR004765]", "NSF attachment protein [IPR000744]", "NUDE family [IPR033494]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1 [IPR031199]", "Na(+)/H(+) exchange regulatory cofactor NHERF-1/2 [IPR017300]", "Nck-associated protein 1 [IPR019137]", "Negative elongation factor E [IPR033102]", "Nesprin-2 [IPR030266]", "Nestin [IPR031211]", "Neurochondrin [IPR008709]", "Neurofilament light polypeptide [IPR027692]", "Neurofilament medium polypeptide [IPR027697]", "Neurogenic locus Notch 2 [IPR022336]", "Neuropilin [IPR014648]", "Neuropilin-1 [IPR027146]", "Neuroplastin [IPR027112]", "Niban-like [IPR026088]", "Nibrin [IPR016592]", "Nibrin-related [IPR040227]", "Nicalin [IPR016574]", "Nicastrin [IPR008710]", "Nicotinamide phosphoribosyl transferase [IPR016471]", "Nitric oxide synthase-interacting protein [IPR016818]", "Non-specific endonuclease [IPR040255]", "Nonaspanin (TM9SF) [IPR004240]", "Nonsense-mediated mRNA decay protein 3 [IPR039722]", "Nonsense-mediated mRNA decay protein Nmd2/UPF2 [IPR039762]", "Not2/Not3/Not5 [IPR040168]", "Notch [IPR008297]", "Nuclear MIS12/MIND complex subunit PMF1/Nnf1 [IPR007128]", "Nuclear RNA export factor [IPR030217]", "Nuclear RNA-splicing-associated protein, SR-25 [IPR019532]", "Nuclear cap-binding protein subunit 1 [IPR027159]", "Nuclear cap-binding protein subunit 3 [IPR019416]", "Nuclear factor hnRNPA1 [IPR021662]", "Nuclear fragile X mental retardation-interacting protein 2 [IPR032747]", "Nuclear mitotic apparatus protein 1 [IPR026650]", "Nuclear polyadenylated RNA-binding protein Nab2/ZC3H14 [IPR040366]", "Nuclear pore complex protein NUP98-NUP96 [IPR037637]", "Nuclear pore complex protein Nup133-like [IPR037624]", "Nuclear pore complex protein [IPR026054]", "Nuclear pore glycoprotein p62, metazoa [IPR033072]", "Nuclear pore membrane glycoprotein 210-like [IPR045197]", "Nuclear pore protein 84/107 [IPR007252]", "Nuclear protein DGCR14/ESS-2 [IPR019148]", "Nuclear protein localization protein 4 [IPR016563]", "Nuclear transport factor 2/Mtr2 [IPR045875]", "Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 [IPR026633]", "Nucleobindin [IPR040250]", "Nucleobindin-1 [IPR040253]", "Nucleobindin-2 [IPR028813]", "Nucleolar GTP-binding protein 1 [IPR024926]", "Nucleolar GTP-binding protein 2 [IPR024929]", "Nucleolar complex protein 2 [IPR005343]", "Nucleolar complex protein 4 [IPR027193]", "Nucleolar complex-associated protein 3 [IPR016903]", "Nucleolar protein 10/Enp2 [IPR040382]", "Nucleolar protein 11 [IPR042859]", "Nucleolar protein 14 [IPR007276]", "Nucleolar protein 7 [IPR039626]", "Nucleolar protein 9 [IPR040000]", "Nucleolar protein Nop56/Nop58 [IPR045056]", "Nucleolar, Nop52 [IPR010301]", "Nucleoplasmin family [IPR004301]", "Nucleoporin NSP1/NUP62 [IPR026010]", "Nucleoporin NUP88/NUP82 [IPR037700]", "Nucleoporin Nup120/160 [IPR021717]", "Nucleoporin Nup186/Nup192/Nup205 [IPR021827]", "Nucleoporin Nup188 [IPR044840]", "Nucleoporin Nup37 [IPR037626]", "Nucleoporin Nup54/Nup57/Nup44 [IPR024864]", "Nucleoporin Nup85-like [IPR011502]", "Nucleoporin Nup88 [IPR019321]", "Nucleoporin Seh1 [IPR037597]", "Nucleoporin interacting component Nup93/Nic96 [IPR007231]", "Nucleoporin p58/p45 [IPR024882]", "Nucleoporin peptidase S59-like [IPR037665]", "Nucleoporin protein Ndc1-Nup [IPR019049]", "Nucleoporin, NUP53 [IPR017389]", "Nucleoporin, Nup155-like [IPR004870]", "Nucleoside 2-deoxyribosyltransferase [IPR007710]", "Nucleoside diphosphate kinase [IPR001564]", "Nucleoside transporter ENT1/ENT2 [IPR034764]", "Nucleoside-triphosphatase, THEP1 type [IPR004948]", "Nucleosome assembly protein (NAP) [IPR002164]", "Nucleosome-remodeling factor subunit BPTF [IPR038028]", "NudC domain-containing protein 3 [IPR027761]", "NudC family [IPR037898]", "Nurim-like [IPR033580]", "OBG-type GTPase [IPR045086]", "OCIA domain-containing protein 1/2 [IPR040187]", "ODR-4-like [IPR029454]", "Occludin [IPR002958]", "Oligoribonuclease [IPR022894]", "Oligosaccharyl transferase complex, subunit OST3/OST6 [IPR021149]", "Oligosaccharyl transferase, STT3 subunit [IPR003674]", "Optic atrophy 3-like [IPR010754]", "Origin recognition complex, subunit 2 [IPR007220]", "Origin recognition complex, subunit 3 [IPR020795]", "Origin recognition complex, subunit 5 [IPR020796]", "Ornithine aminotransferase [IPR010164]", "Orotate phosphoribosyltransferase [IPR023031]", "Orotidine 5'-phosphate decarboxylase [IPR014732]", "Oxidized purine nucleoside triphosphate [IPR003563]", "Oxysterol-binding protein [IPR000648]", "P-type ATPase [IPR001757]", "P-type ATPase subfamily IIC, subunit alpha [IPR005775]", "P-type ATPase, subfamily IIA, SERCA-type [IPR005782]", "P-type ATPase, subfamily V [IPR006544]", "P-type ATPase, subfamily IIA, PMR1-type [IPR006413]", "P-type ATPase, subfamily IIB [IPR006408]", "PA2G4 family [IPR004545]", "PAT complex subunit CCDC47 [IPR012879]", "PAX family [IPR043565]", "PDCD5-like [IPR002836]", "PDK/BCKDK protein kinase [IPR039028]", "PDZ and LIM domain protein 1 [IPR028537]", "PDZ domain-containing protein 8 [IPR039275]", "PDZ domain-containing protein GIPC1/2/3 [IPR017379]", "PEST proteolytic signal-containing nuclear protein [IPR029169]", "PEX5/PEX5L [IPR024111]", "PH-interacting protein [IPR028738]", "PHD finger protein 10 [IPR038045]", "PHF5-like [IPR005345]", "PITH domain-containing protein 1-like [IPR045099]", "PP2B [IPR043360]", "Pachytene checkpoint protein 2-like [IPR044539]", "Palmitoyl protein thioesterase [IPR002472]", "Palmitoyl-protein thioesterase 1 [IPR030294]", "Palmitoyltransferase ZDHHC13 [IPR030290]", "Pannexin [IPR039099]", "Pantothenate kinase, acetyl-CoA regulated, two-domain type [IPR015844]", "Paraneoplastic encephalomyelitis antigen [IPR002343]", "Paraoxonase2 [IPR008364]", "Parvin [IPR028433]", "Pat1-like [IPR039900]", "Pentatricopeptide repeat domain-containing protein 3 [IPR037387]", "Peptidase A22B, signal peptide peptidase [IPR007369]", "Peptidase C13, legumain [IPR001096]", "Peptidase C1B, bleomycin hydrolase [IPR004134]", "Peptidase C2, calpain family [IPR022684]", "Peptidase C26 [IPR011697]", "Peptidase C26, gamma-glutamyl hydrolase [IPR015527]", "Peptidase C54 [IPR005078]", "Peptidase C65, otubain [IPR019400]", "Peptidase C69, dipeptidase A [IPR005322]", "Peptidase C78, ubiquitin fold modifier-specific peptidase 1/ 2 [IPR012462]", "Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase [IPR001930]", "Peptidase M1, aminopeptidase B [IPR015571]", "Peptidase M13 [IPR000718]", "Peptidase M14B, caboxypeptidase D [IPR015567]", "Peptidase M17, leucine aminopeptidase [IPR023042]", "Peptidase M17, leucine aminopeptidase/peptidase B [IPR011356]", "Peptidase M20 [IPR002933]", "Peptidase M24, methionine aminopeptidase [IPR001714]", "Peptidase M24A, methionine aminopeptidase, subfamily 1 [IPR002467]", "Peptidase M24A, methionine aminopeptidase, subfamily 2 [IPR002468]", "Peptidase M28 family [IPR045175]", "Peptidase M3A/M3B [IPR045090]", "Peptidase S10, serine carboxypeptidase [IPR001563]", "Peptidase S1A, Tysnd1 [IPR017345]", "Peptidase S26B [IPR001733]", "Peptidase S28 [IPR008758]", "Peptidase S8, subtilisin-related [IPR015500]", "Peptidase S9A, prolyl oligopeptidase [IPR002470]", "Peptidase T1A, proteasome beta-subunit [IPR000243]", "Peptidase family M49 [IPR039461]", "Peptidase, FtsH [IPR005936]", "Peptide chain release factor eRF1/aRF1 [IPR004403]", "Peptidyl-prolyl cis-trans isomerase E [IPR016304]", "Peptidyl-prolyl cis-trans isomerase FKBP2/11 [IPR044609]", "Peptidyl-prolyl cis-trans isomerase FKBP3 [IPR043368]", "Peptidyl-prolyl cis-trans isomerase FKBP4 [IPR031212]", "Peptidyl-prolyl cis-trans isomerase FKBP5 [IPR031210]", "Peptidyl-prolyl cis-trans isomerase PIN4 [IPR043323]", "Peptidyl-tRNA hydrolase, PTH2 [IPR002833]", "Pericentriolar material 1 protein [IPR024138]", "Perilipin [IPR004279]", "Periodic tryptophan protein 1 [IPR044285]", "Periodic tryptophan protein 2 [IPR027145]", "Periphilin-1 [IPR028851]", "Peroxiredoxin, AhpC-type [IPR024706]", "Peroxiredoxin-5-like [IPR037944]", "Peroxiredoxin-like 2A [IPR032802]", "Peroxiredoxin-like 2A/B/C [IPR032801]", "Peroxisomal acyl-coenzyme A oxidase [IPR034171]", "Peroxisomal membrane protein 14 [IPR025655]", "Peroxisomal membrane protein 4 [IPR019531]", "Peroxisomal targeting signal 1 receptor PEX5, animals [IPR024113]", "Peroxisomal/glyoxysomal leader peptide-processing protease [IPR039245]", "Peroxysomal long chain fatty acyl transporter [IPR005283]", "Pescadillo [IPR010613]", "Pex19 protein [IPR006708]", "Phenylalanine-tRNA ligase, class IIc, beta subunit [IPR045060]", "Phenylalanyl-tRNA synthetase, class IIc, alpha subunit [IPR004529]", "Phenylalanyl-tRNA synthetase, class IIc, beta subunit, archael/eukaryotic type [IPR004531]", "Phosducin-like [IPR045037]", "Phosphatase Gpp1/Gpp2-like [IPR045228]", "Phosphatidate cytidylyltransferase [IPR000374]", "Phosphatidate cytidylyltransferase, eukaryota [IPR016720]", "Phosphatidate cytidylyltransferase, mitochondrial [IPR015222]", "Phosphatidyl serine synthase [IPR004277]", "Phosphatidylethanolamine-binding protein [IPR008914]", "Phosphatidylethanolamine-binding protein, eukaryotic [IPR035810]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1 [IPR042165]", "Phosphatidylglycerophosphatase and protein-tyrosine phosphatase 1-like [IPR044596]", "Phosphatidylinositol kinase [IPR015433]", "Phosphatidylinositol transfer protein [IPR001666]", "Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma [IPR016279]", "Phosphatidylinositol-4-phosphate 5-kinase [IPR023610]", "Phosphatidylinositol-binding clathrin assembly protein [IPR030412]", "Phosphatidylinositol-glycan biosynthesis class S protein [IPR019540]", "Phosphatidylserine decarboxylase [IPR033177]", "Phosphatidylserine decarboxylase, eukaryotic type 1 [IPR033661]", "Phosphatidylserine decarboxylase-related [IPR003817]", "Phosphoacetylglucosamine mutase [IPR016657]", "Phosphodiesterase MJ0936/Vps29 [IPR000979]", "Phosphoenolpyruvate carboxykinase, GTP-utilising [IPR008209]", "Phosphoglucomutase [IPR045244]", "Phosphoglucose isomerase (PGI) [IPR001672]", "Phosphoglycerate kinase [IPR001576]", "Phosphoglycerate mutase 1 [IPR005952]", "Phosphoinositide phospholipase C family [IPR001192]", "Phospholipase B-like [IPR007000]", "Phosphoribosylformylglycinamidine cyclo-ligase [IPR004733]", "Phosphoribosylformylglycinamidine synthase PurL [IPR010073]", "Phosphoribosylglycinamide formyltransferase [IPR004607]", "Phosphoribosylglycinamide synthetase [IPR000115]", "Phosphorylase kinase alpha/beta subunit [IPR008734]", "Phosphorylated adapter RNA export protein [IPR039047]", "Phosphoserine aminotransferase [IPR022278]", "Phosphotyrosyl phosphatase activator, PTPA [IPR004327]", "Pinin [IPR039853]", "Pirin [IPR012093]", "Plakin [IPR043197]", "Plakophilin/Delta catenin [IPR028435]", "Plasma membrane calcium-transporting ATPase 1 [IPR030320]", "Plasminogen activator inhibitor 1 RNA-binding protein [IPR027205]", "Plastin-1 [IPR030235]", "Plastin-2/3 [IPR039956]", "Plectin [IPR030269]", "Plexin family [IPR031148]", "Polo kinase kinase [IPR022165]", "Poly(A) polymerase [IPR014492]", "Poly(ADP-ribose) glycohydrolase [IPR007724]", "Poly-U binding splicing factor, PUF60-like [IPR006532]", "Polyadenylate binding protein, human types 1, 2, 3, 4 [IPR006515]", "Polyadenylate-binding protein 2 [IPR034911]", "Polyadenylate-binding protein-interacting protein 2-like [IPR040396]", "Polycomb protein EED [IPR037352]", "Polynucleotide kinase 3 phosphatase [IPR013954]", "Polyprenyl synthetase [IPR000092]", "Polyribonucleotide 5-hydroxyl-kinase Clp1/Grc3 [IPR045116]", "Polyribonucleotide nucleotidyltransferase [IPR012162]", "Porin, eukaryotic type [IPR001925]", "Porphobilinogen deaminase [IPR000860]", "Pre-mRNA 3' end processing protein Pfs2-like [IPR045245]", "Pre-mRNA-processing factor 19 [IPR038959]", "Pre-mRNA-processing factor 6/Prp1/STA1 [IPR027108]", "Pre-mRNA-processing factor Prp40 [IPR039726]", "Pre-mRNA-processing-splicing factor 8 [IPR027652]", "Pre-mRNA-splicing factor Cwf15/Cwc15 [IPR006973]", "Pre-mRNA-splicing factor 38 [IPR005037]", "Pre-mRNA-splicing factor Cwc2/Slt11 [IPR039171]", "Pre-mRNA-splicing factor Isy1 [IPR009360]", "Pre-mRNA-splicing factor SPF27 [IPR008409]", "Pre-mRNA-splicing factor Spp2-like [IPR045166]", "Pre-mRNA-splicing factor Syf1-like [IPR045075]", "Pre-mRNA-splicing regulator WTAP [IPR033757]", "Pre-rRNA-processing protein Esf1 [IPR039754]", "Pre-rRNA-processing protein PNO1-like [IPR039912]", "Prefoldin alpha subunit, archaea-type [IPR011599]", "Prefoldin alpha-like [IPR004127]", "Prefoldin beta-like [IPR002777]", "Prefoldin subunit 2 [IPR027235]", "Prefoldin subunit 3 [IPR016655]", "Prefoldin, subunit 4 [IPR016661]", "Prenylated rab acceptor PRA1 [IPR004895]", "Prenylcysteine oxidase [IPR017046]", "Prenyltransferase subunit beta [IPR045089]", "Presenilin/signal peptide peptidase [IPR006639]", "Primosome PriB/single-strand DNA-binding [IPR000424]", "Probable ubiquitin carboxyl-terminal hydrolase FAF-X [IPR031226]", "Profilin [IPR005455]", "Profilin-1 [IPR029892]", "Profilin-2 [IPR029891]", "Profilin1/2/3, vertebrate [IPR005454]", "Progesterone-induced-blocking factor 1 [IPR026205]", "Programmed cell death protein 4 [IPR039778]", "Prohibitin [IPR000163]", "Proliferating cell nuclear antigen, PCNA [IPR000730]", "Proline-rich AKT1 substrate 1 protein [IPR026682]", "Proline-rich protein PRCC [IPR018800]", "Proline-tRNA ligase, class IIa, archaeal-type [IPR004499]", "Prolyl 3-hydroxylase 1 [IPR039837]", "Prolyl 3-hydroxylase [IPR039575]", "Prolyl 4-hydroxylase [IPR045054]", "Prostaglandin E synthase 2 [IPR034334]", "Prostaglandin reductase 2 [IPR037399]", "Prostate apoptosis response 4 [IPR026117]", "Proteasomal ubiquitin receptor Rpn13/ADRM1 [IPR006773]", "Proteasome B-type subunit [IPR023333]", "Proteasome activator PA28 [IPR009077]", "Proteasome activator complex subunit 4 [IPR035309]", "Proteasome alpha-type subunit [IPR023332]", "Proteasome assembly chaperone 1 [IPR016565]", "Proteasome assembly chaperone 2 [IPR019151]", "Proteasome assembly chaperone 2, eukaryotic [IPR016562]", "Proteasome assembly chaperone 3 [IPR018788]", "Proteasome beta 3 subunit [IPR033811]", "Proteasome component Ecm29 [IPR024372]", "Proteasome inhibitor PI31-like [IPR045128]", "Proteasome subunit alpha 1 [IPR035144]", "Proteasome subunit alpha 3 [IPR037555]", "Proteasome subunit alpha 7 [IPR035190]", "Proteasome subunit alpha2 [IPR034644]", "Proteasome subunit alpha4 [IPR034647]", "Proteasome subunit alpha5 [IPR033812]", "Proteasome subunit alpha6 [IPR034642]", "Proteasome subunit beta 1 [IPR035202]", "Proteasome subunit beta 2 [IPR035206]", "Proteasome subunit beta 4 [IPR016295]", "Proteasome subunit beta 5 [IPR037558]", "Proteasome subunit beta 6 [IPR035140]", "Proteasome subunit beta 7 [IPR035216]", "Proteasome, subunit alpha/beta [IPR001353]", "Protein AATF/Bfr2 [IPR039223]", "Protein BRAWNIN [IPR027858]", "Protein C10 [IPR026317]", "Protein C3orf33-like [IPR042421]", "Protein CDV3 [IPR026806]", "Protein CIP2A [IPR042510]", "Protein CUSTOS [IPR026694]", "Protein Cms1 [IPR032704]", "Protein DEK [IPR044198]", "Protein ERGIC-53 [IPR033085]", "Protein FAM3C [IPR039219]", "Protein FAM8A1 [IPR039871]", "Protein FMC1 homologue [IPR037667]", "Protein FRG1 [IPR010414]", "Protein Fyv10/E3 ubiquitin-protein transferase MAEA [IPR027714]", "Protein Hgh1 [IPR039717]", "Protein ICln/Lot5/Saf5 [IPR039924]", "Protein LCHN/Anr2 [IPR018626]", "Protein LYRIC [IPR031402]", "Protein LZIC [IPR040065]", "Protein Lsm12-like [IPR039683]", "Protein Mon2-like [IPR026829]", "Protein NCBP2AS2 [IPR042407]", "Protein NDRG3 [IPR030692]", "Protein Njmu-R1 [IPR028280]", "Protein OS-9-like [IPR045149]", "Protein PBDC1, metazoa/fungi [IPR008476]", "Protein PRRC1 [IPR026534]", "Protein PRRC2 [IPR033184]", "Protein Pet100 [IPR018625]", "Protein Peter Pan-like [IPR045112]", "Protein RCC2 [IPR028641]", "Protein Red-like [IPR039896]", "Protein S100-A10 [IPR028476]", "Protein S100-A11 [IPR028482]", "Protein SMG8 [IPR028802]", "Protein SON [IPR032922]", "Protein Sec13 [IPR037596]", "Protein Sgt1-like [IPR044563]", "Protein Spindly, chordates [IPR028593]", "Protein TFG [IPR033512]", "Protein Yip1/4-like [IPR045231]", "Protein arginine N-methyltransferase PRMT5 [IPR007857]", "Protein arginine N-methyltransferase [IPR025799]", "Protein arginine methyltransferase NDUFAF7 [IPR003788]", "Protein canopy homolog [IPR042415]", "Protein disulfide-isomerase A6-like [IPR044569]", "Protein disulphide isomerase [IPR005792]", "Protein disulphide-isomerase A4 [IPR017068]", "Protein flightless-1 [IPR029919]", "Protein furry/Tao3/Mor2 [IPR039867]", "Protein import receptor MAS20 [IPR002056]", "Protein import receptor MAS20, metazoan [IPR022422]", "Protein jagunal [IPR009787]", "Protein kinase C and casein kinase substrate in neurons protein 2 [IPR028521]", "Protein kinase C and casein kinase substrate in neurons protein 3 [IPR028523]", "Protein kinase C, delta [IPR027436]", "Protein kinase C, delta/epsilon/eta/theta types [IPR014376]", "Protein kinase C-binding protein 1 [IPR021931]", "Protein kinase Mps1 family [IPR027084]", "Protein kish [IPR009653]", "Protein of unknown function DUF1075 [IPR009432]", "Protein of unknown function DUF1387 [IPR009816]", "Protein of unknown function DUF2046 [IPR019152]", "Protein of unknown function DUF4615 [IPR029274]", "Protein of unknown function DUF719 [IPR007998]", "Protein patched/dispatched [IPR003392]", "Protein phosphatase 1 regulatory subunit 12A/B/C [IPR017401]", "Protein phosphatase 2A regulatory subunit PR55 [IPR000009]", "Protein phosphatase 2A, regulatory B subunit, B56 [IPR002554]", "Protein phosphatase 2C family [IPR015655]", "Protein phosphatase 4 core regulatory subunit R2 [IPR015267]", "Protein phosphatase methylesterase, eukaryotic [IPR016812]", "Protein regulator of cytokinesis 1 [IPR032921]", "Protein spinster-like [IPR044770]", "Protein suppressor of sable-like [IPR045124]", "Protein translocase SEC61 complex, gamma subunit [IPR008158]", "Protein translocase complex, SecE/Sec61-gamma subunit [IPR001901]", "Protein transport Sec61-beta/Sbh [IPR030671]", "Protein transport protein Got1 [IPR045176]", "Protein transport protein SEC31-like [IPR040251]", "Protein transport protein Sec23 [IPR037364]", "Protein transport protein SecG/Sec61-beta/Sbh [IPR016482]", "Protein unc-119 homologue A-like [IPR032977]", "Protein virilizer [IPR026736]", "Protein wntless [IPR009551]", "Protein-L-histidine N-pros-methyltransferase [IPR007884]", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase [IPR000682]", "Protein-S-isoprenylcysteine O-methyltransferase [IPR025770]", "Protein-glutamate O-methyltransferase [IPR039763]", "Protein-tyrosine phosphatase, low molecular weight [IPR017867]", "Protein-tyrosine phosphatase, low molecular weight, mammalian [IPR002115]", "Protein-tyrosine phosphatase, non-receptor type-1/2 [IPR012265]", "Protein-tyrosine phosphatase, non-receptor type-6, -11 [IPR012152]", "Protein-tyrosine phosphatase-like, PTPLA [IPR007482]", "Protein/nucleic acid deglycase DJ-1 [IPR006287]", "Proteinase inhibitor I25A, stefin [IPR001713]", "Protoporphyrinogen oxidase [IPR004572]", "Pseudouridine synthase I, TruA [IPR001406]", "Pseudouridine synthase PUS1/ PUS2-like [IPR041708]", "Pseudouridine synthase, TruD [IPR001656]", "Pterin 4 alpha carbinolamine dehydratase [IPR001533]", "Pumilio homologue 3 [IPR040059]", "Purine 5'-nucleotidase [IPR016695]", "Purine nucleoside phosphorylase I, inosine/guanosine-specific [IPR011270]", "Purine nucleoside phosphorylase [IPR011268]", "Purine-rich element binding protein family [IPR006628]", "Purine-rich element-binding protein alpha [IPR030500]", "Putative peptidyl-tRNA hydrolase PTRHD1 [IPR042237]", "Pyridine nucleotide-disulphide oxidoreductase, class I [IPR001100]", "Pyridoxal phosphate homeostasis protein [IPR011078]", "Pyridoxal phosphate-dependent decarboxylase [IPR002129]", "Pyridoxamine 5'-phosphate oxidase [IPR000659]", "Pyridoxine kinase [IPR004625]", "Pyrimidine 5'-nucleotidase, eukaryotic [IPR006434]", "Pyrroline-5-carboxylate reductase [IPR000304]", "Pyruvate carboxylase [IPR005930]", "Pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit, subgroup y [IPR017597]", "Pyruvate dehydrogenase E1 component subunit beta [IPR027110]", "Pyruvate kinase [IPR001697]", "Queuine tRNA-ribosyltransferase accessory subunit QTRTD1 [IPR028592]", "Queuosine salvage protein family [IPR019438]", "RAB11-binding protein RELCH [IPR040362]", "RAD3/XPD family [IPR001945]", "RFT1 [IPR007594]", "RFX-like DNA-binding protein [IPR039779]", "RINT-1/Tip20 [IPR007528]", "RLI1 [IPR013283]", "RNA (C5-cytosine) methyltransferase [IPR023267]", "RNA (C5-cytosine) methyltransferase, NOP2 [IPR023273]", "RNA 3'-terminal phosphate cyclase [IPR000228]", "RNA 3'-terminal phosphate cyclase type 1 [IPR017770]", "RNA 3'-terminal phosphate cyclase type 2 [IPR016443]", "RNA binding protein HABP4/SERBP1 [IPR039764]", "RNA cytidine acetyltransferase NAT10 [IPR033688]", "RNA demethylase ALKBH5 [IPR032860]", "RNA exonuclease 4 [IPR034920]", "RNA methyltransferase Bin3-like [IPR039772]", "RNA polymerase I associated factor, A49-like [IPR009668]", "RNA polymerase II associated factor Paf1 [IPR007133]", "RNA polymerase II transcription factor SIII, subunit A [IPR010684]", "RNA polymerase II transcriptional coactivator Sub1/Tcp4-like [IPR045125]", "RNA polymerase II-associated protein RPAP1/Rba50 [IPR039913]", "RNA polymerase subunit Rpb4/RPC9 [IPR005574]", "RNA polymerase subunit Rpb7-like [IPR045113]", "RNA polymerase-associated protein Ctr9 [IPR031101]", "RNA transcription, translation and transport factor protein [IPR019265]", "RNA-binding motif protein 8 [IPR008111]", "RNA-binding protein 10 [IPR033095]", "RNA-binding protein 26 [IPR034861]", "RNA-binding protein 26/27 [IPR045137]", "RNA-binding protein 45 [IPR033101]", "RNA-binding protein 5 [IPR033094]", "RNA-binding protein 6 [IPR028806]", "RNA-binding protein EWS [IPR033109]", "RNA-binding protein FUS [IPR034459]", "RNA-binding protein NOB1 [IPR039907]", "RNA-binding protein Nova-2 [IPR033087]", "RNA-induced silencing complex, nuclease component Tudor-SN [IPR016685]", "RNA-splicing ligase RtcB homologue, eukaryotic [IPR027513]", "RNA-splicing ligase, RtcB [IPR001233]", "RNase P subunit Pop5/Rpp14/Rnp2-like [IPR002759]", "RNase P subunit p30 [IPR002738]", "RPA-related protein RADX [IPR040893]", "RZZ complex, subunit Zw10 [IPR009361]", "RZZ complex, subunit Zwilch [IPR018630]", "Rab GDI protein [IPR000806]", "Rab GTPase-activating protein 1 [IPR033185]", "Rab-like protein 6 [IPR040385]", "Rab11-family interacting protein class I [IPR037789]", "Rab12 [IPR041830]", "Rab21 [IPR041833]", "Rab24 [IPR041828]", "Rab35 [IPR041815]", "Rab39 [IPR041818]", "Rab3GAP catalytic subunit [IPR045700]", "Rab3GAP regulatory subunit [IPR026059]", "Rab4 [IPR041819]", "Rab9 [IPR041824]", "Rabaptin [IPR003914]", "Rabaptin-5 [IPR029880]", "Rad21/Rec8-like protein [IPR039781]", "Ragulator complex protein LAMTOR2-like [IPR037587]", "RalBP1-associated Eps domain-containing protein 1 [IPR026814]", "Ran GTPase [IPR002041]", "Ran binding protein RanBP1-like [IPR045255]", "Rap guanine nucleotide exchange factor 2 [IPR030739]", "Rap1 GTPase-GDP dissociation stimulator 1 [IPR040144]", "Ras GTPase GNL1-like [IPR043358]", "Ras GTPase-activating protein-binding protein 1 [IPR034375]", "Ras GTPase-activating protein-binding protein 2 [IPR034377]", "Ras GTPase-activating protein-binding protein [IPR039539]", "Ras-like guanine nucleotide exchange factor [IPR008937]", "Ras-related protein Rab-23 [IPR034114]", "Ras-related protein Rab14 [IPR030702]", "Ras-related protein Ral [IPR028412]", "Ras-related protein Rap2 [IPR041840]", "Reduced folate carrier [IPR002666]", "Reduced folate transporter SLC19A1 [IPR028339]", "Refilin family [IPR028215]", "Remodeling and spacing factor 1-like [IPR028938]", "Remodelling complex subunit Rsc/polybromo [IPR037382]", "Renin receptor-like [IPR012493]", "Replication factor A protein 1 [IPR004591]", "Replication factor A protein 2 [IPR014646]", "Replication factor A protein 3 [IPR013970]", "Replication factor A protein-like [IPR040260]", "Replication factor C subunit 1 [IPR012178]", "Reticulon-4-interacting protein 1 [IPR037397]", "Retinal rod rhodopsin-sensitive cGMP 3', 5'-cyclic phosphodiesterase, delta subunit [IPR017287]", "Retinoblastoma-binding protein 5/Swd1 [IPR037850]", "Retrieval of early ER protein Rer1 [IPR004932]", "Rho GTPase-activating protein 10 [IPR035486]", "Rho protein GDP-dissociation inhibitor [IPR000406]", "Rho-associated protein kinase 1/2 [IPR020684]", "Rho-related GTP-binding protein RhoG [IPR042734]", "Riboflavin kinase [IPR023468]", "Ribonuclease CAF1 [IPR006941]", "Ribonuclease H2, subunit A [IPR004649]", "Ribonuclease H2, subunit C [IPR013924]", "Ribonuclease HII/HIII [IPR001352]", "Ribonuclease III [IPR011907]", "Ribonuclease Nob1, eukaryote [IPR017117]", "Ribonuclease P protein subunit Rpp29/RNP1 [IPR002730]", "Ribonuclease P protein subunit Rpp40 [IPR013893]", "Ribonuclease P/MRP subunit Rpp29 [IPR016848]", "Ribonuclease T2, eukaryotic [IPR033697]", "Ribonuclease T2-like [IPR001568]", "Ribonucleases P/MRP protein subunit Pop1 [IPR039182]", "Ribonucleoprotein PTB-binding 1 [IPR034635]", "Ribonucleoside-diphosphate reductase large subunit [IPR039718]", "Ribonucleotide reductase small subunit [IPR033909]", "Ribonucleotide reductase small subunit family [IPR000358]", "Ribophorin I [IPR007676]", "Ribose-phosphate pyrophosphokinase [IPR005946]", "Ribose-phosphate pyrophosphokinase, bacterial-type [IPR037515]", "Ribosomal RNA adenine dimethylase [IPR011530]", "Ribosomal RNA adenine methyltransferase KsgA/Erm [IPR001737]", "Ribosomal RNA assembly KRR1 [IPR024166]", "Ribosomal RNA large subunit methyltransferase E [IPR015507]", "Ribosomal RNA processing protein 8 [IPR007823]", "Ribosomal RNA-processing protein 15 [IPR012459]", "Ribosomal RNA-processing protein 7 [IPR040446]", "Ribosomal RNA-processing protein Rrp9-like [IPR039241]", "Ribosomal biogenesis NSA2 family [IPR039411]", "Ribosomal biogenesis regulatory protein [IPR007023]", "Ribosomal biogenesis, methyltransferase, EMG1/NEP1 [IPR005304]", "Ribosomal export protein Nmd3 [IPR039768]", "Ribosomal protein L1 [IPR002143]", "Ribosomal protein L1, mitochondrial [IPR005879]", "Ribosomal protein L1/ribosomal biogenesis protein [IPR028364]", "Ribosomal protein L10P [IPR001790]", "Ribosomal protein L10e [IPR001197]", "Ribosomal protein L11, bacterial-type [IPR006519]", "Ribosomal protein L11/L12 [IPR000911]", "Ribosomal protein L12/P1/P2 family [IPR027534]", "Ribosomal protein L13 [IPR005822]", "Ribosomal protein L13, bacterial-type [IPR005823]", "Ribosomal protein L13, eukaryotic/archaeal [IPR005755]", "Ribosomal protein L13e [IPR001380]", "Ribosomal protein L14 [IPR039660]", "Ribosomal protein L14P [IPR000218]", "Ribosomal protein L15 [IPR030878]", "Ribosomal protein L15, bacterial-type [IPR005749]", "Ribosomal protein L15e [IPR000439]", "Ribosomal protein L16 [IPR000114]", "Ribosomal protein L17 [IPR000456]", "Ribosomal protein L18e [IPR000039]", "Ribosomal protein L19 [IPR001857]", "Ribosomal protein L2 [IPR002171]", "Ribosomal protein L2, archaeal-type [IPR023672]", "Ribosomal protein L20 [IPR005813]", "Ribosomal protein L21 [IPR001787]", "Ribosomal protein L21-like [IPR028909]", "Ribosomal protein L21e [IPR001147]", "Ribosomal protein L22, bacterial/chloroplast-type [IPR005727]", "Ribosomal protein L22/L17 [IPR001063]", "Ribosomal protein L22/L17, eukaryotic/archaeal [IPR005721]", "Ribosomal protein L22e [IPR002671]", "Ribosomal protein L23 [IPR019985]", "Ribosomal protein L24 [IPR003256]", "Ribosomal protein L24e [IPR023438]", "Ribosomal protein L24e-related [IPR000988]", "Ribosomal protein L25/L23 [IPR013025]", "Ribosomal protein L26/L24, eukaryotic/archaeal [IPR005756]", "Ribosomal protein L27/L41, mitochondrial [IPR019189]", "Ribosomal protein L27e [IPR001141]", "Ribosomal protein L28/L24 [IPR026569]", "Ribosomal protein L28/L40, mitochondrial [IPR019192]", "Ribosomal protein L28e [IPR002672]", "Ribosomal protein L29/L35 [IPR001854]", "Ribosomal protein L29e [IPR002673]", "Ribosomal protein L3 [IPR000597]", "Ribosomal protein L3, archaeal/eukaryotic type [IPR045077]", "Ribosomal protein L3, bacterial/organelle-type [IPR019927]", "Ribosomal protein L30/YlxQ [IPR039109]", "Ribosomal protein L30e [IPR000231]", "Ribosomal protein L31e [IPR000054]", "Ribosomal protein L32e [IPR001515]", "Ribosomal protein L34Ae [IPR008195]", "Ribosomal protein L35A [IPR001780]", "Ribosomal protein L36e [IPR000509]", "Ribosomal protein L37/S30 [IPR010793]", "Ribosomal protein L37ae [IPR002674]", "Ribosomal protein L37e [IPR001569]", "Ribosomal protein L38e [IPR002675]", "Ribosomal protein L4, eukaryotic and archaeal type [IPR045240]", "Ribosomal protein L4/L1e [IPR002136]", "Ribosomal protein L44e [IPR000552]", "Ribosomal protein L47, mitochondrial [IPR010729]", "Ribosomal protein L49/IMG2 [IPR007740]", "Ribosomal protein L5 [IPR002132]", "Ribosomal protein L5 eukaryotic/L18 archaeal [IPR005485]", "Ribosomal protein L50, mitochondria [IPR018305]", "Ribosomal protein L53, mitochondrial [IPR019716]", "Ribosomal protein L6 [IPR000702]", "Ribosomal protein L7, eukaryotic [IPR005998]", "Ribosomal protein L7/L12 [IPR000206]", "Ribosomal protein L7/L30 [IPR039699]", "Ribosomal protein L7A/L8 [IPR001921]", "Ribosomal protein L7Ae/L8/Nhp2 family [IPR018492]", "Ribosomal protein L9 [IPR000244]", "Ribosomal protein P2 [IPR044076]", "Ribosomal protein S10 [IPR001848]", "Ribosomal protein S10, eukaryotic/archaeal [IPR005729]", "Ribosomal protein S11 [IPR001971]", "Ribosomal protein S12/S23 [IPR006032]", "Ribosomal protein S12e [IPR000530]", "Ribosomal protein S13 [IPR001892]", "Ribosomal protein S14 [IPR001209]", "Ribosomal protein S15 [IPR000589]", "Ribosomal protein S15, bacterial-type [IPR005290]", "Ribosomal protein S15P [IPR023029]", "Ribosomal protein S16 [IPR000307]", "Ribosomal protein S17, archaeal/eukaryotic [IPR028333]", "Ribosomal protein S17/S11 [IPR000266]", "Ribosomal protein S17e [IPR001210]", "Ribosomal protein S18 [IPR001648]", "Ribosomal protein S19/S15 [IPR002222]", "Ribosomal protein S19A/S15e [IPR005713]", "Ribosomal protein S19e [IPR001266]", "Ribosomal protein S2 [IPR001865]", "Ribosomal protein S2, bacteria/mitochondria/plastid [IPR005706]", "Ribosomal protein S2, eukaryotic [IPR027498]", "Ribosomal protein S2, eukaryotic/archaeal [IPR005707]", "Ribosomal protein S21e [IPR001931]", "Ribosomal protein S22, mitochondrial [IPR019374]", "Ribosomal protein S23, eukaryotic/archaeal [IPR005680]", "Ribosomal protein S23, mitochondrial [IPR019520]", "Ribosomal protein S23/S29, mitochondrial [IPR019368]", "Ribosomal protein S24/S35, mitochondrial [IPR039848]", "Ribosomal protein S24e [IPR001976]", "Ribosomal protein S25 [IPR004977]", "Ribosomal protein S27/S33, mitochondrial [IPR013219]", "Ribosomal protein S28, mitochondrial [IPR019375]", "Ribosomal protein S28e [IPR000289]", "Ribosomal protein S29, mitochondrial [IPR008092]", "Ribosomal protein S3, eukaryotic/archaeal [IPR005703]", "Ribosomal protein S30 [IPR006846]", "Ribosomal protein S30, mitochondrial [IPR039982]", "Ribosomal protein S3Ae [IPR001593]", "Ribosomal protein S4/S9 [IPR022801]", "Ribosomal protein S4/S9, eukaryotic/archaeal [IPR005710]", "Ribosomal protein S4e [IPR000876]", "Ribosomal protein S5 [IPR000851]", "Ribosomal protein S5, eukaryotic/archaeal [IPR005711]", "Ribosomal protein S5/S7 [IPR000235]", "Ribosomal protein S5/S7, eukaryotic/archaeal [IPR005716]", "Ribosomal protein S6 [IPR000529]", "Ribosomal protein S6 kinase II [IPR016239]", "Ribosomal protein S6, eukaryotic [IPR014401]", "Ribosomal protein S6e [IPR001377]", "Ribosomal protein S7e [IPR000554]", "Ribosomal protein S8 [IPR000630]", "Ribosomal protein S8e [IPR001047]", "Ribosomal protein S8e/ribosomal biogenesis NSA2 [IPR022309]", "Ribosomal protein S9 [IPR000754]", "Ribosome assembly factor Mrt4 [IPR033867]", "Ribosome biogenesis factor, NIP7 [IPR016686]", "Ribosome biogenesis protein BRX1 [IPR026532]", "Ribosome biogenesis protein Bms1/Tsr1 [IPR039761]", "Ribosome biogenesis protein Nop16 [IPR019002]", "Ribosome biogenesis protein Nop53/GLTSCR2 [IPR011687]", "Ribosome biogenesis protein Rpf2 [IPR039770]", "Ribosome biogenesis protein Slx9-like [IPR028160]", "Ribosome maturation protein Sdo1/SBDS [IPR002140]", "Ribosome maturation protein Sdo1/SBDS-like [IPR039100]", "Ribosome recycling factor [IPR002661]", "Ribosome-binding ATPase YchF/Obg-like ATPase 1 [IPR004396]", "Ribosome-binding protein 1 [IPR040248]", "RidA family [IPR006056]", "Rieske iron-sulphur protein [IPR014349]", "Root UVB sensitive family [IPR006968]", "RuvB-like [IPR027238]", "RuvB-like helicase 1 [IPR037938]", "RuvB-like helicase 2 [IPR037942]", "S-adenosylmethionine synthetase [IPR002133]", "S-formylglutathione hydrolase [IPR014186]", "S-phase kinase-associated protein 1 [IPR016897]", "S-phase kinase-associated protein 1-like [IPR001232]", "SAC3/GANP/THP3 [IPR045107]", "SAFB-like transcription modulator [IPR034780]", "SAGA-associated factor 29 [IPR037802]", "SAP30-binding protein [IPR012479]", "SAPAP family [IPR005026]", "SCAMP [IPR007273]", "SCAR/WAVE family [IPR028288]", "SERRATE/Ars2 [IPR039727]", "SH3-binding, glutamic acid-rich protein [IPR006993]", "SHC SH2 domain-binding protein 1-like [IPR045140]", "SIT4 phosphatase-associated protein family [IPR007587]", "SKI-interacting protein, SKIP [IPR017862]", "SLAIN motif-containing protein [IPR026179]", "SLC12A transporter family [IPR004842]", "SNF5/SMARCB1/INI1 [IPR006939]", "SNU66/SART1 family [IPR005011]", "SNX17/27/31 [IPR037831]", "SOS response associated peptidase (SRAP) [IPR003738]", "SOUL haem-binding protein [IPR006917]", "SPIN90/Ldb17 [IPR030125]", "SSNA1 family [IPR033362]", "SUMO-activating enzyme subunit Uba2 [IPR030661]", "SUN domain-containing protein 1 [IPR018539]", "SUN domain-containing protein 1-5 [IPR045119]", "SUN domain-containing protein 2 [IPR030272]", "SURP and G-patch domain-containing protein 1/2 [IPR040169]", "SWI/SNF complex subunit BAF57 [IPR030089]", "SWI/SNF complex subunit BAF60B [IPR030090]", "SWI/SNF complex subunit BRG1 [IPR030100]", "SWI/SNF complex subunit SMARCC1 [IPR030087]", "SWI/SNF complex subunit SMARCC2 [IPR038044]", "SWI/SNF-like complex subunit BAF250a [IPR030094]", "SWI/SNF-like complex subunit BAF250/Osa [IPR021906]", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 [IPR038041]", "SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1 [IPR027109]", "SWR1-complex protein 5/Craniofacial development protein 1/2 [IPR027124]", "Saf4/Yju2 protein [IPR007590]", "Saposin [IPR008373]", "Saposin, chordata [IPR021165]", "Scaffold attachment factor B1 [IPR034781]", "Scaffold attachment factor B2 [IPR034782]", "Scavenger mRNA decapping enzyme DcpS/DCS2 [IPR008594]", "Scc2/Nipped-B family [IPR033031]", "Schlafen family [IPR029684]", "Sda1 [IPR027312]", "Sdc1/DPY30 [IPR037856]", "Sec1-like protein [IPR001619]", "Sec13/Seh1 family [IPR037363]", "Sec20 [IPR005606]", "SecY/SEC61-alpha family [IPR002208]", "Selenium-binding protein [IPR008826]", "Selenophosphate synthetase [IPR004536]", "Sentrin-specific protease 3 [IPR037945]", "Sepiapterin reductase [IPR006393]", "Septin 2 [IPR008113]", "Septin 3 [IPR008114]", "Septin 6 [IPR030644]", "Septin 7 [IPR008115]", "Septin 9 [IPR030645]", "Septin [IPR016491]", "Septin and tuftelin interacting protein [IPR024933]", "Serine hydroxymethyltransferase [IPR001085]", "Serine-tRNA ligase, type1 [IPR002317]", "Serine/arginine-rich splicing factor 10 [IPR034476]", "Serine/arginine-rich splicing factor 11 [IPR034447]", "Serine/arginine-rich splicing factor 2-like [IPR034893]", "Serine/arginine-rich splicing factor 6 [IPR029541]", "Serine/threonine protein phosphatase 5 [IPR011236]", "Serine/threonine-protein kinase MRCK beta [IPR033232]", "Serine/threonine-protein kinase OSR1 [IPR028749]", "Serine/threonine-protein kinase PAK2 [IPR035065]", "Serine/threonine-protein kinase RAC alpha [IPR039027]", "Serine/threonine-protein kinase SMG1 [IPR031559]", "Serine/threonine-protein kinase TOR [IPR026683]", "Serine/threonine-protein kinase Vps15-like [IPR045162]", "Serine/threonine-protein phosphatase 2A subunit A, metazoa [IPR031090]", "Serine/threonine-protein phosphatase 4 regulatory subunit 1 [IPR031087]", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit [IPR037979]", "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit [IPR037981]", "Serpin H1 [IPR033547]", "Serpin family [IPR000215]", "Short coiled-coil protein [IPR019357]", "Short transmembrane mitochondrial protein 1 [IPR027854]", "Short-chain dehydrogenase/reductase SDR [IPR002347]", "Sideroflexin-4 [IPR028825]", "Sigma intracellular receptor 2 [IPR016964]", "Signal peptidase complex catalytic subunit SEC11A [IPR037712]", "Signal peptidase complex subunit 3 [IPR007653]", "Signal peptidase complex subunit Spc2/SPCS2 [IPR009582]", "Signal recognition particle SRP9 [IPR039914]", "Signal recognition particle receptor, beta subunit [IPR019009]", "Signal recognition particle subunit SRP68 [IPR026258]", "Signal recognition particle, SRP14 subunit [IPR003210]", "Signal recognition particle, SRP19 subunit [IPR002778]", "Signal recognition particle, SRP54 subunit [IPR022941]", "Signal recognition particle, SRP54 subunit, eukaryotic [IPR006325]", "Signal recognition particle, SRP72 subunit [IPR026270]", "Signal recognition particle, SRP9 subunit [IPR008832]", "Sin3 associated polypeptide p18 [IPR010516]", "Single-stranded DNA-binding protein [IPR011344]", "Sirtuin family [IPR003000]", "Sister chromatid cohesion protein Pds5 [IPR039776]", "Ski3/TTC37 [IPR039226]", "Sla2 family [IPR030224]", "Slowmo/Ups family [IPR037365]", "Sm-like protein Lsm6/SmF [IPR016487]", "Sm-like protein Lsm7 [IPR017132]", "Sm-like protein Lsm7/SmG [IPR044641]", "Smac/DIABLO protein [IPR015142]", "Small (40S) ribosomal subunit Asc1/RACK1 [IPR045223]", "Small GTPase Rho [IPR003578]", "Small GTPase [IPR001806]", "Small GTPase superfamily, ARF type [IPR024156]", "Small GTPase superfamily, ARF/SAR type [IPR006689]", "Small GTPase superfamily, SAR1-type [IPR006687]", "Small GTPase, Ras-type [IPR020849]", "Small kinetochore-associated protein [IPR033373]", "Small nuclear ribonucleoprotein E [IPR027078]", "Small nuclear ribonucleoprotein Sm D2 [IPR027248]", "Small nuclear ribonucleoprotein Sm D3 [IPR034099]", "Small-subunit processome, Utp11 [IPR007144]", "Small-subunit processome, Utp14 [IPR006709]", "Smg8/Smg9 [IPR019354]", "Smooth muscle protein/calponin [IPR003096]", "Snf7 family [IPR005024]", "Snf8/Vps36 family [IPR040608]", "Sodium/potassium-transporting ATPase subunit beta [IPR000402]", "Sodium/potassium-transporting ATPase subunit beta, chordates [IPR015565]", "Sodium:dicarboxylate symporter [IPR001991]", "Solute carrier family 12 member 1/2 [IPR002443]", "Solute carrier family 12 member 2 [IPR002444]", "Solute carrier family 25 member 44 [IPR042164]", "Solute carrier family 35 member SLC35F1/F2/F6 [IPR009262]", "Sorbitol dehydrogenase-like [IPR045306]", "Sorting nexin 9 family [IPR014536]", "Sorting nexin-1 [IPR028660]", "Sorting nexin-17 [IPR028666]", "Sorting nexin-2 [IPR028653]", "Sorting nexin-27 [IPR028667]", "Sorting nexin-4 [IPR034783]", "Sorting nexin-5 [IPR028654]", "Sorting nexin-5/6/32 [IPR014637]", "Sorting nexin-6 [IPR028657]", "Sorting nexin-8/Mvp1 [IPR028662]", "Sorting nexin-9 [IPR028644]", "Spartin-like [IPR045036]", "Spastin [IPR017179]", "Spastin, chordate [IPR035106]", "Spectrin, beta subunit [IPR016343]", "Spermatid perinuclear RNA-binding protein [IPR030446]", "Spermatogenesis-defective protein 39 [IPR040057]", "Spermidine/spermine synthase, eukaryotes [IPR030668]", "Spermidine/spermine synthases [IPR001045]", "Spermine synthase, animal [IPR015576]", "Sphingomyelin phosphodiesterase 4 [IPR024129]", "Sphingosine N-acyltransferase Lag1/Lac1-like [IPR016439]", "Spindle assembly checkpoint component Mad1 [IPR008672]", "Splicing factor 3A subunit 1 [IPR045146]", "Splicing factor 3A subunit 3 [IPR031776]", "Splicing factor 3B subunit 1-like [IPR038737]", "Splicing factor 45 [IPR040052]", "Splicing factor ELAV/Hu [IPR006548]", "Splicing factor Yju2 [IPR043701]", "Splicing factor, RBM39-like [IPR006509]", "Splicing factor, arginine/serine-rich 19 [IPR042841]", "Squalene cyclase [IPR018333]", "Squalene monooxygenase [IPR040125]", "Squalene synthase-like [IPR006449]", "Squalene/phytoene synthase [IPR002060]", "Stathmin family [IPR000956]", "Sterile alpha and TIR motif-containing protein 1 [IPR039184]", "Steroidogenic acute regulatory protein-like [IPR000799]", "Sterol O-acyltransferase, ACAT/DAG/ARE types [IPR014371]", "Sterol O-acyltransferase, metazoa [IPR030687]", "Sterol transport protein NPC2-like [IPR039670]", "Stomatin [IPR028515]", "Stomatin/HflK/HflC family [IPR001972]", "Structural maintenance of chromosomes flexible hinge domain-containing protein 1 [IPR038892]", "Structural maintenance of chromosomes protein 1A, metazoan [IPR029683]", "Structural maintenance of chromosomes protein 5 [IPR027131]", "Structural maintenance of chromosomes protein [IPR024704]", "Structure-specific recognition protein [IPR000969]", "Succinate dehydrogenase, flavoprotein subunit [IPR011281]", "Succinate dehydrogenase/fumarate reductase iron-sulphur protein [IPR004489]", "Succinate dehydrogenase/fumarate reductase, flavoprotein subunit [IPR014006]", "Succinate semialdehyde dehydrogenase [IPR010102]", "Succinate--CoA synthetase, beta subunit [IPR005809]", "Succinyl-CoA ligase, alpha subunit [IPR005810]", "Sugar/inositol transporter [IPR003663]", "Sulfhydryl oxidase [IPR039798]", "Sulfotransferase [IPR005331]", "Sulfurtransferase TST/MPST-like [IPR045078]", "Sulphide quinone-reductase [IPR015904]", "Suppressor of white apricot [IPR040397]", "Surface antigen D15-like [IPR039910]", "Surfeit locus 1/4 [IPR045214]", "Surfeit locus 4 [IPR002995]", "Surfeit locus 6 [IPR007019]", "Symplekin/Pta1 [IPR021850]", "Synaptic vesicle protein SV2 [IPR022308]", "Synaptobrevin [IPR001388]", "Synaptogyrin [IPR016579]", "Syndetin [IPR040047]", "Syntaxin [IPR045242]", "Syntenin-1 [IPR030528]", "Synthesis of cytochrome c oxidase, Sco1/Sco2 [IPR017276]", "T-complex 11 [IPR008862]", "T-complex protein 1, alpha subunit [IPR012715]", "T-complex protein 1, beta subunit [IPR012716]", "T-complex protein 1, delta subunit [IPR012717]", "T-complex protein 1, epsilon subunit [IPR012718]", "T-complex protein 1, eta subunit [IPR012720]", "T-complex protein 1, gamma subunit [IPR012719]", "T-complex protein 1, theta subunit [IPR012721]", "T-complex protein 1, zeta subunit [IPR012722]", "TACC family [IPR039915]", "TAF15/EWS/TLS family [IPR034870]", "TAP46-like protein [IPR007304]", "TATA binding associated factor 15 [IPR034875]", "TATA element modulatory factor 1 DNA binding [IPR022092]", "TATA-Box binding protein-like [IPR015445]", "TATA-box binding protein [IPR000814]", "TB2/DP1/HVA22-related protein [IPR004345]", "TCF25/Rqc1 [IPR006994]", "TE2IP/Rap1 [IPR039595]", "TFIIH subunit Tfb1/GTF2H1 [IPR027079]", "TFP11/STIP/Ntr1 [IPR045211]", "TH1 protein [IPR006942]", "THO complex subunit 2 [IPR040007]", "THO complex subunit 6 [IPR042626]", "THO complex, subunit 5 [IPR019163]", "THO complex, subunit THOC1 [IPR021861]", "THRAP3/BCLAF1 family [IPR029199]", "THUMP domain-containing protein 1-like [IPR040183]", "TMEM115/Pdh1/Rbl19 [IPR013861]", "TMEM14 family [IPR005349]", "TMEM192 family [IPR029399]", "TMEM206 protein [IPR029366]", "TMEM33/Pom33 family [IPR005344]", "TMEM70 family [IPR009724]", "TMEM70/TMEM186/TMEM223 protein family [IPR045325]", "TMEM85/ER membrane protein complex subunit 4 [IPR009445]", "TOX high mobility group box family member 4 [IPR037985]", "TPP-binding domain containing protein HACL1-like [IPR045025]", "TPX2 [IPR009675]", "TRAPP I complex, subunit 5 [IPR016696]", "TREX component Tex1/THOC3 [IPR040132]", "TRIC channel [IPR007866]", "Tankyrase 1-binding protein-like [IPR040006]", "Tapasin [IPR008056]", "Target of Myb protein 1 [IPR014645]", "Target of Myb1-like 2 [IPR027429]", "TatD family [IPR001130]", "TatSF1-like [IPR034393]", "Taxilin family [IPR026183]", "Tectonic [IPR040354]", "Telomerase RNA component interacting RNase [IPR038838]", "Telomere-associated protein Rif1 [IPR028566]", "Testin [IPR027683]", "Testis-expressed protein 10/pre-rRNA-processing protein Ipi1 [IPR037947]", "Tetrahydrofolate dehydrogenase/cyclohydrolase [IPR000672]", "Tetraspanin, animals [IPR000301]", "Tetraspanin/Peripherin [IPR018499]", "Tetratricopeptide repeat protein 19 [IPR040395]", "Tetratricopeptide repeat protein 26 [IPR030511]", "Tetratricopeptide repeat protein 38 [IPR033891]", "Tetratricopeptide repeat protein TTC27/Emw1 [IPR044244]", "The Golgi pH regulator/GPCR-type G protein [IPR015672]", "The WD repeat Cdc20/Fizzy family [IPR033010]", "ThiF/MoeB/HesA family [IPR045886]", "Thiamine pyrophosphate enzyme [IPR045229]", "Thiolase [IPR002155]", "Thioredoxin domain-containing protein 15 [IPR042418]", "Thioredoxin domain-containing protein 17-like [IPR045108]", "Thioredoxin-related transmembrane protein 2 [IPR039101]", "Thioredoxin/glutathione reductase selenoprotein [IPR006338]", "Threonine-tRNA ligase, class IIa [IPR002320]", "Thymidine kinase [IPR001267]", "Thymidylate kinase [IPR018094]", "Thymidylate synthase [IPR000398]", "Thymidylate synthase/dCMP hydroxymethylase [IPR045097]", "Thyroid hormone receptor-associated protein 3 [IPR026667]", "Tight junction protein ZO [IPR005417]", "Tight junction protein ZO-1 [IPR005418]", "Tight junction protein ZO-2 [IPR005419]", "Tim23-like [IPR045238]", "Tim44-like [IPR039544]", "Timeless [IPR044998]", "Tissue alpha-L-fucosidase [IPR028755]", "TmcA/NAT10/Kre33 [IPR032672]", "Tom40 [IPR037930]", "Torsin 1/2 [IPR017378]", "Torsin [IPR010448]", "Torsin-1A [IPR030549]", "Torsin-1A-interacting protein 1/2 [IPR008662]", "Torsin-1B [IPR030550]", "TraB/PrgY/GumN family [IPR002816]", "Trafficking protein particle complex subunit [IPR007233]", "Trans-isoprenyl diphosphate synthases, eukaryotic-type [IPR044844]", "Transaldolase type 1 [IPR004730]", "Transaldolase/Fructose-6-phosphate aldolase [IPR001585]", "Transcription elongation factor SPT5 [IPR039659]", "Transcription elongation factor Spt5, eukaryote [IPR017071]", "Transcription elongation factor Spt6 [IPR017072]", "Transcription elongation factor, IIS-type [IPR035100]", "Transcription elongation factor, TFIIS [IPR006289]", "Transcription elongation factor, mitochondrial [IPR039150]", "Transcription elongation regulator 1-like [IPR045148]", "Transcription facto Tfc3-like [IPR044210]", "Transcription factor BTF3 [IPR039370]", "Transcription factor E [IPR039997]", "Transcription factor II-I [IPR016659]", "Transcription factor IIIC subunit Tfc1/Sfc1 [IPR040454]", "Transcription factor STAT [IPR001217]", "Transcription factor TFIIB [IPR000812]", "Transcription factor TFIIH subunit p52/Tfb2 [IPR004598]", "Transcription factor Tfc4/TFIIIC-102/Sfc4 [IPR039340]", "Transcription factor cyclic AMP-dependent, CRE-BP1-type [IPR016378]", "Transcription factor, GA-binding, alpha subunit [IPR016312]", "Transcription factor, enhancer of yellow 2 [IPR018783]", "Transcription initiation factor IIF, alpha subunit [IPR008851]", "Transcription initiation factor IIF, beta subunit [IPR003196]", "Transcription initiation factor TFIID, 23-30kDa subunit [IPR003923]", "Transcription intermediary factor 1-beta [IPR037373]", "Transcription termination factor, mitochondrial/chloroplastic [IPR003690]", "Transcription-associated protein 1 [IPR033317]", "Transcriptional regulatory protein Sin3-like [IPR039774]", "Transcriptional regulatory protein Sin3a [IPR037969]", "Transcriptional repressor p66 [IPR040386]", "Transducin beta-like protein 2 [IPR042410]", "Transferrin receptor protein 1 [IPR029513]", "Transforming growth factor-beta-related [IPR015615]", "Transgelin-2 [IPR001061]", "Translation Initiation factor eIF- 4e [IPR001040]", "Translation elongation factor EF1A, eukaryotic/archaeal [IPR004539]", "Translation elongation factor EFG/EF2 [IPR004540]", "Translation elongation factor EFTs/EF1B [IPR001816]", "Translation elongation factor EFTu/EF1A, bacterial/organelle [IPR004541]", "Translation elongation factor IF5A-like [IPR001884]", "Translation initiation factor 2, alpha subunit [IPR011488]", "Translation initiation factor 2A [IPR011387]", "Translation initiation factor 3 complex subunit L [IPR019382]", "Translation initiation factor IF- 2 [IPR015760]", "Translation initiation factor IF2/IF5 [IPR045196]", "Translation initiation factor IF6 [IPR002769]", "Translation initiation factor aIF-2, bacterial-like [IPR000178]", "Translation machinery associated TMA7 [IPR015157]", "Translation machinery-associated protein 16 [IPR021346]", "Translation release factor pelota [IPR004405]", "Translational activator Gcn1 [IPR033173]", "Translationally controlled tumour protein [IPR018105]", "Translin [IPR033956]", "Translin family [IPR002848]", "Translocation associated membrane protein [IPR016447]", "Translocation protein Sec62 [IPR004728]", "Translocation protein Sec63 [IPR027137]", "Translocator protein [IPR030164]", "Translocon-associated [IPR008855]", "Translocon-associated protein (TRAP), alpha subunit [IPR005595]", "Translocon-associated protein subunit gamma [IPR009779]", "Transmembrane emp24 domain-containing protein 5 [IPR015717]", "Transmembrane emp24 domain-containing protein 7 [IPR015718]", "Transmembrane emp24 domain-containing protein [IPR015720]", "Transmembrane protein 109 [IPR039492]", "Transmembrane protein 126 [IPR009801]", "Transmembrane protein 131-like [IPR039877]", "Transmembrane protein 160 [IPR026801]", "Transmembrane protein 161A/B [IPR019395]", "Transmembrane protein 201 [IPR040041]", "Transmembrane protein 205 [IPR042623]", "Transmembrane protein 214 [IPR019308]", "Transmembrane protein 230 [IPR044234]", "Transmembrane protein 230/134 [IPR008590]", "Transmembrane protein 35A/B [IPR040399]", "Transmembrane protein 43 family [IPR012430]", "Transmembrane protein 65 [IPR019537]", "Transmembrane protein GPR107/GPR108-like [IPR009637]", "Transmembrane protein TqsA-like [IPR002549]", "Transport protein particle (TRAPP) component [IPR007194]", "Transposase, L1 [IPR004244]", "Treacle protein [IPR017859]", "Tricarboxylate/iron carrier [IPR004686]", "Triosephosphate isomerase [IPR000652]", "Triosephosphate isomerase, bacterial/eukaryotic [IPR022896]", "Trm112-like [IPR005651]", "Tropomodulin [IPR004934]", "Tropomodulin-1 [IPR030135]", "Tropomodulin-3 [IPR030133]", "Tropomyosin [IPR000533]", "Tryptophan-tRNA ligase [IPR002306]", "Tryptophan-tRNA ligase, bacterial-type [IPR024109]", "TspO/MBR-related protein [IPR004307]", "Tubulin [IPR000217]", "Tubulin binding cofactor A [IPR004226]", "Tubulin epsilon and delta complex protein 1 [IPR043535]", "Tubulin--tyrosine ligase-like protein 12 [IPR027749]", "Tubulin-folding cofactor D [IPR033162]", "Tubulin-specific chaperone E [IPR044994]", "Tubulin-tyrosine ligase/Tubulin polyglutamylase [IPR004344]", "Tumor necrosis factor alpha-induced protein 8-like [IPR008477]", "Tumour protein D52 [IPR007327]", "Tweety [IPR006990]", "Twinfilin [IPR028458]", "Twinkle-like protein [IPR027032]", "Type 1 protein exporter [IPR039421]", "Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase [IPR002591]", "Type II pantothenate kinase [IPR004567]", "Type II phosphatidylinositol 4-kinase Lsb6/PI4K2 [IPR039756]", "Tyrosine-tRNA ligase [IPR002307]", "Tyrosine-tRNA ligase, bacterial-type [IPR024088]", "Tyrosine/threonine-protein kinase, Cdc2 inhibitor [IPR016235]", "U1 small nuclear ribonucleoprotein C [IPR017340]", "U2 auxiliary factor small subunit [IPR009145]", "U2 small nuclear ribonucleoprotein A' [IPR044640]", "U2 snRNP auxilliary factor, large subunit, splicing factor [IPR006529]", "U3 small nucleolar RNA-associated protein 10 [IPR040191]", "U3 small nucleolar RNA-associated protein 18 [IPR045161]", "U3 small nucleolar RNA-associated protein 25 [IPR010678]", "U3 small nucleolar RNA-associated protein 6 [IPR013949]", "U3 small nucleolar ribonucleoprotein complex, subunit Mpp10 [IPR012173]", "U3 snoRNP protein/Ribosome production factor 1 [IPR044281]", "U4/U6 small nuclear ribonucleoprotein Prp3 [IPR027104]", "U4/U6 small nuclear ribonucleoprotein Prp31 [IPR027105]", "U4/U6.U5 small nuclear ribonucleoprotein component Snu23 [IPR040107]", "U6 snRNA-associated Sm-like protein LSm2 [IPR016654]", "U6 snRNA-associated Sm-like protein Lsm1/8 [IPR044642]", "U6 snRNA-associated Sm-like protein Lsm3 [IPR040002]", "UAA transporter [IPR013657]", "UBAP2/protein lingerer [IPR022166]", "UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110kDa subunit [IPR037919]", "UDP-glucose 6-dehydrogenase, eukaryotic type [IPR028356]", "UDP-glucose/GDP-mannose dehydrogenase [IPR017476]", "UDP-glucose:Glycoprotein Glucosyltransferase [IPR009448]", "UDP-glucuronic acid decarboxylase [IPR044516]", "UDP-glucuronosyl/UDP-glucosyltransferase [IPR002213]", "UDP-sugar pyrophosphorylase [IPR039741]", "UDPGP family [IPR002618]", "UHRF1/2-like [IPR045134]", "UMP-CMP kinase [IPR006266]", "UPF0600 protein C5orf51 [IPR037657]", "UPF0767 family [IPR031933]", "USP39 [IPR033809]", "UTP--glucose-1-phosphate uridylyltransferase [IPR016267]", "UV excision repair protein Rad23 [IPR004806]", "UbiA prenyltransferase domain containing protein 1 [IPR026046]", "UbiA prenyltransferase family [IPR000537]", "Ubiquilin-1/2 [IPR028430]", "Ubiquinol-cytochrome c chaperone, CBP3 [IPR007129]", "Ubiquinol-cytochrome c chaperone/UPF0174 [IPR021150]", "Ubiquinol-cytochrome-c reductase complex assembly factor 2 [IPR037698]", "Ubiquinone biosynthesis O-methyltransferase [IPR010233]", "Ubiquitin binding protein, Hrs/VPS27 [IPR017073]", "Ubiquitin carboxyl-terminal hydrolase 10 [IPR028767]", "Ubiquitin carboxyl-terminal hydrolase 14-like [IPR044635]", "Ubiquitin conjugation factor E4 [IPR045132]", "Ubiquitin domain-containing protein UBFD1 [IPR039120]", "Ubiquitin fusion degradation protein Ufd1-like [IPR004854]", "Ubiquitin thioesterase OTUB1 [IPR030298]", "Ubiquitin thioesterase Otubain [IPR016615]", "Ubiquitin-activating enzyme E1 [IPR018075]", "Ubiquitin-fold modifier-conjugating enzyme 1 [IPR014806]", "Ubiquitin-like modifier Hub1/Ubl5 [IPR039732]", "Ubiquitin-like modifier-activating enzyme Atg7 [IPR006285]", "Ubiquitin-like-conjugating enzyme Atg3/Atg10 [IPR007135]", "Ubiquitin-protein ligase E3B/C [IPR044611]", "Ubiquitin-specific peptidase 24 [IPR033382]", "Ubiquitin/SUMO-activating enzyme E1 [IPR000011]", "Ubiquitinyl hydrolase [IPR016652]", "Ubiquitinyl hydrolase, UCH37 type [IPR017390]", "Ubiquitously expressed transcript protein UXT [IPR003994]", "Uncharacterised protein family UPF0449 [IPR028227]", "Uncharacterised protein family UPF0640 [IPR028183]", "Uncharacterised protein family, TMEM59 [IPR022065]", "Uncharacterized protein KIAA2013-like [IPR018795]", "Unconventional myosin-XVIIIa [IPR031244]", "Uracil-DNA glycosylase family 1 [IPR002043]", "Ureohydrolase [IPR006035]", "Uridine kinase-like [IPR000764]", "Uridine-cytidine kinase 2 [IPR029925]", "Uroporphyrinogen decarboxylase HemE [IPR006361]", "V-type ATPase, V0 complex, 116kDa subunit family [IPR002490]", "V-type ATP synthase catalytic alpha chain [IPR022878]", "V-type ATP synthase regulatory subunit B/beta [IPR022879]", "V-type ATPase subunit E [IPR002842]", "V0 complex accessory subunit Ac45 [IPR008388]", "VPRBP/DCAF1 family [IPR033270]", "Vacuolar ATPase assembly integral membrane protein Vma21 [IPR019013]", "Vacuolar fusion protein Mon1 [IPR004353]", "Vacuolar import/degradation protein Vid24 [IPR018618]", "Vacuolar protein sorting protein 26 related [IPR028934]", "Vacuolar protein sorting protein 36 [IPR037855]", "Vacuolar protein sorting-associated Vps28 [IPR007143]", "Vacuolar protein sorting-associated protein 13 [IPR026847]", "Vacuolar protein sorting-associated protein 16 [IPR016534]", "Vacuolar protein sorting-associated protein 29 [IPR028661]", "Vacuolar protein sorting-associated protein 33 [IPR027121]", "Vacuolar protein sorting-associated protein 35 [IPR005378]", "Vacuolar protein sorting-associated protein 4 [IPR031255]", "Vacuolar protein sorting-associated protein 51 [IPR014812]", "Vacuolar protein sorting-associated protein 53 [IPR039766]", "Vacuolar protein sorting-associated protein 9-like [IPR045046]", "Vacuolar protein sorting-associated protein Ist1 [IPR005061]", "Vacuolar protein sorting-associated protein Vta1-like [IPR044538]", "Vacuolar protein-sorting protein Bro1-like [IPR045251]", "Valine-tRNA ligase [IPR002303]", "Vam6/VPS39/TRAP1 family [IPR032914]", "Vang-like protein [IPR009539]", "Vesicle transport protein, Got1/SFT2-like [IPR007305]", "Vesicle-associated membrane-protein-associated protein [IPR016763]", "Vesicle-fusing ATPase [IPR039812]", "Vesicle-trafficking protein Sec22 [IPR044565]", "Vezatin [IPR026858]", "Villin/Gelsolin [IPR007122]", "Vimentin [IPR027699]", "Vinculin [IPR017997]", "Vinculin/alpha-catenin [IPR006077]", "Vinexin [IPR028510]", "Vitamin K epoxide reductase complex subunit 1 [IPR042406]", "Vitamin K-dependent gamma-carboxylase [IPR007782]", "Voltage-dependent anion-selective channel protein 1 [IPR030270]", "Voltage-dependent anion-selective channel protein 2 [IPR030277]", "Voltage-dependent anion-selective channel protein 3 [IPR030271]", "Vps72/YL1 family [IPR008895]", "WASH complex subunit 3 [IPR019309]", "WASH complex subunit 7 [IPR027307]", "WASH complex, subunit strumpellin [IPR019393]", "WD repeat BOP1/Erb1 [IPR028598]", "WD repeat Prp46/PLRG1-like [IPR045241]", "WD repeat WDR12/Ytm1 [IPR028599]", "WD repeat-containing protein 73 [IPR042795]", "WD repeat-containing protein 89 [IPR039328]", "WD repeat-containing protein 91 [IPR039724]", "WD repeat-containing protein DCAF7-like [IPR045159]", "WD repeat-containing protein WDR18/Ipi3/RID3 [IPR045227]", "WD repeat-containing protein WDR46/Utp7 [IPR040315]", "WD40 repeat-containing protein SMU1 [IPR045184]", "WDR74/Nsa1 [IPR037379]", "WW domain binding protein 11 [IPR019007]", "WW domain-binding protein 2 [IPR033598]", "WW domain-binding protein 2-like [IPR044852]", "Wings apart-like protein [IPR039874]", "Wolframin [IPR026208]", "Wolframin family [IPR026209]", "XAP5 protein [IPR007005]", "XMAP215 family [IPR045110]", "XPG/Rad2 endonuclease [IPR006084]", "YAP-binding/ALF4/Glomulin [IPR013877]", "YIP1 family member 3 [IPR026637]", "YLP motif-containing protein 1 [IPR026314]", "YTH domain containing protein [IPR045168]", "YgfZ/GcvT [IPR045179]", "Yif1 family [IPR005578]", "YjeF N-terminal domain-containing protein NAXE-like [IPR032976]", "YjgF/YER057c/UK114 family [IPR006175]", "ZPR1 family [IPR040141]", "Zinc finger CCHC domain-containing protein 3 [IPR042509]", "Zinc finger CCHC-type and RNA-binding motif-containing protein 1 [IPR044598]", "Zinc finger FYVE domain containing protein, SARA/endofin [IPR035438]", "Zinc finger FYVE domain-containing protein, endofin [IPR017165]", "Zinc finger HIT domain-containing protein 2 [IPR039646]", "Zinc finger protein 532-like [IPR045914]", "Zinc finger protein 622/Rei1/Reh1 [IPR040025]", "Zinc finger protein 638 [IPR033096]", "Zinc finger protein-like 1 [IPR039043]", "Zinc transporter Msc2-like [IPR045316]", "Zinc/iron permease [IPR003689]", "cAMP-dependent protein kinase catalytic subunit [IPR044109]", "cAMP-dependent protein kinase regulatory subunit [IPR012198]", "dCTP pyrophosphatase 1 [IPR025984]", "dTDP-4-dehydrorhamnose reductase family [IPR005913]", "hnRNP A2/B1 [IPR034489]", "mRNA 3'-end-processing protein Rna14-like [IPR045243]", "mRNA cap guanine-N7 methyltransferase [IPR039753]", "mRNA cap guanine-N7 methyltransferase, eukaryotes [IPR016899]", "mRNA capping enzyme, bifunctional [IPR017074]", "mRNA export factor Gle2/RAE1 [IPR037631]", "mRNA splicing factor Cwf18-like [IPR013169]", "mRNA-decapping enzyme subunit 1 [IPR010334]", "p53 and DNA damage-regulated protein 1 [IPR030482]", "p53 tumour suppressor family [IPR002117]", "rRNA biogenesis protein RRP36 [IPR009292]", "rRNA biogenesis protein Rrp5 [IPR045209]", "siRNA-mediated silencing protein NRDE-2 [IPR013633]", "tRNA (1-methyladenosine) methyltransferase catalytic subunit Gcd14 [IPR014816]", "tRNA (C5-cytosine) methyltransferase, NCL1 [IPR023270]", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 [IPR017423]", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit [IPR028884]", "tRNA (guanine-N-7) methyltransferase catalytic subunit Trm8, eukaryote [IPR025763]", "tRNA (guanine-N-7) methyltransferase, Trmb type [IPR003358]", "tRNA (guanine-N1-)-methyltransferase, eukaryotic [IPR007356]", "tRNA (uracil(54)-C(5))-methyltransferase, eukaryotic type [IPR045850]", "tRNA guanosine-2'-O-methyltransferase, TRM11 [IPR016691]", "tRNA isopentenyltransferase, eukaryotes [IPR030666]", "tRNA methyltransferase 10 homologue C [IPR025812]", "tRNA methyltransferase, Trm1 [IPR002905]", "tRNA modification GTPase MnmE [IPR004520]", "tRNA pseudouridine synthase B family [IPR004802]", "tRNA pseudouridine synthase II, TruB [IPR014780]", "tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase MiaB [IPR006463]", "tRNA-guanine transglycosylase [IPR004803]", "tRNA-specific 2-thiouridylase [IPR004506]", "von Willebrand factor A domain-containing protein 8 [IPR039891]"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABHD12", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACAD10", "ACADM", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGL", "AGPS", "AHCY", "AHCYL1", "AHSA1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKT1", "AKT1S1", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANKLE2", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEX1", "API5", "APLP2", "APOC1", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP10", "ARHGAP5", "ARHGDIA", "ARID1A", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC6", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD3A", "ATAD3B", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATXN2L", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRI3BP", "BRIP1", "BRIX1", "BROX", "BSG", "BTF3", "BUB1B", "BUD23", "BUD31", "BYSL", "C10orf76", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf35", "C2CD2", "C2CD2L", "C2CD5", "C2orf49", "C3orf33", "C3orf58", "C5orf24", "C5orf51", "C8orf33", "C9orf64", "CAB39", "CABIN1", "CAD", "CALD1", "CALR", "CALU", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CAST", "CBR1", "CBX3", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCDC94", "CCDC97", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC20", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDKAL1", "CDS2", "CDV3", "CEBPZ", "CELF2", "CENPB", "CENPH", "CENPK", "CENPP", "CENPU", "CEP131", "CEP170", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1L", "CHD8", "CHERP", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CIAPIN1", "CIP2A", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COIL", "COLGALT1", "COMMD2", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CROT", "CRTAP", "CS", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC27", "CWF19L1", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DCAF1", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDT", "DDX54", "DEK", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX29", "DIABLO", "DIAPH1", "DIAPH3", "DIDO1", "DIEXF", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EED", "EEF1A2", "EEF1E1", "EEF1G", "EFCAB14", "EFHD1", "EFHD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2B1", "EIF2B2", "EIF2B4", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERICH1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ESF1", "ESS2", "ETF1", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXO1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAH", "FAM114A2", "FAM120A", "FAM129B", "FAM160B2", "FAM162A", "FAM173A", "FAM177A1", "FAM207A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FERMT2", "FH", "FHL1", "FHOD1", "FIS1", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FN3KRP", "FNBP1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC1", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAL", "GALK1", "GALM", "GALNS", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GEMIN4", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GID4", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GM2A", "GMDS", "GMFB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPATCH11", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPT2", "GPX8", "GRPEL1", "GRSF1", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDHD2", "HDHD3", "HDHD5", "HEATR1", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMCES", "HMGA1", "HMGB1", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPC", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HTATSF1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IGHMBP2", "IK", "IKBIP", "ILF3", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS14", "INTS2", "INTS3", "INTS5", "INTS9", "IPO4", "IPO5", "IQCB1", "IRGQ", "IRS4", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "JAGN1", "JAM3", "JPT2", "JUP", "KARS", "KATNA1", "KDELR1", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF5B", "KIFBP", "KIN", "KLC1", "KLC2", "KNSTRN", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMBRD1", "LMF2", "LNPEP", "LONP1", "LONP2", "LRPAP1", "LRPPRC", "LRRC41", "LRRC47", "LSM12", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED2", "MAGT1", "MAK16", "MAN1A1", "MAN1A2", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCKS", "MARCKSL1", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPST", "MPV17", "MPV17L2", "MRE11", "MRFAP1", "MRI1", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS6", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSN", "MTA1", "MTA2", "MTAP", "MTBP", "MTDH", "MTERF3", "MTFP1", "MTFR1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTR", "MTX1", "MTX2", "MVD", "MXRA7", "MYBBP1A", "MYCBP", "MYDGF", "MYEF2", "MYG1", "MYO18A", "NAA10", "NAA15", "NAA16", "NAA40", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCLN", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDRG3", "NDUFA13", "NDUFA4", "NDUFAF3", "NDUFAF7", "NDUFB10", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NELFB", "NELFCD", "NELFE", "NES", "NFKBIL1", "NFS1", "NHP2", "NIF3L1", "NIP7", "NIPBL", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL9", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRDE2", "NRM", "NRP1", "NSA2", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUTF2", "NXF1", "OAT", "OCIAD1", "OCLN", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAIP2", "PAK2", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARN", "PARVA", "PATL1", "PAWR", "PAX6", "PAXBP1", "PBDC1", "PBRM1", "PC", "PCBD1", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDP1", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD8", "PEBP1", "PECR", "PELO", "PES1", "PET100", "PEX14", "PEX19", "PEX5", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PJA2", "PKM", "PKMYT1", "PLA2G15", "PLBD2", "PLCG1", "PLEC", "PLIN3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CC", "PPP1R12A", "PPP1R14B", "PPP2R1A", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PXMP4", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "R3HCC1", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP5", "RBBP6", "RBM10", "RBM17", "RBM22", "RBM26", "RBM27", "RBM39", "RBM45", "RBM5", "RBM6", "RBM8A", "RCC2", "RCL1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "REXO2", "REXO4", "RFC1", "RFK", "RFLNB", "RFT1", "RFX1", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOX2", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNMT", "RNPEP", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARS", "SARS2", "SART1", "SBDS", "SCAF1", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCLY", "SCO1", "SCO2", "SCOC", "SCPEP1", "SCRN1", "SCRN3", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A3", "SF3B1", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SLAIN2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLK", "SLTM", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMCHD1", "SMDT1", "SMG1", "SMG8", "SMIM12", "SMIM4", "SMPD4", "SMS", "SMU1", "SMYD3", "SND1", "SNRPA1", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SPAG9", "SPART", "SPAST", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPNS1", "SPPL2A", "SPR", "SPTBN1", "SPTBN2", "SQLE", "SQOR", "SRFBP1", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPRB", "SRRT", "SRSF10", "SRSF11", "SRSF2", "SRSF6", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STARD3", "STAT1", "STAT3", "STIP1", "STMN1", "STOM", "STOML2", "STRBP", "STRIP1", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYS1", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAPBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBPL1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TCP11L1", "TCTN3", "TECR", "TEDC1", "TEFM", "TERF2IP", "TES", "TEX10", "TFB1M", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TJP1", "TJP2", "TK1", "TKFC", "TLE3", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM131", "TMEM14C", "TMEM160", "TMEM161A", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM30A", "TMEM33", "TMEM35B", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMX2", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO2", "TOE1", "TOM1L2", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPRKB", "TPT1", "TPX2", "TRABD", "TRAM1", "TRAP1", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM28", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSTA3", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBL5", "UBQLN1", "UBR4", "UBR7", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP10", "USP14", "USP24", "USP39", "USP5", "USP9X", "UTP11", "UTP14A", "UTP18", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMA21", "VPS13A", "VPS13D", "VPS16", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VTA1", "VWA8", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDR12", "WDR18", "WDR33", "WDR4", "WDR46", "WDR73", "WDR74", "WDR82", "WDR89", "WDR91", "WFS1", "WLS", "WRN", "WTAP", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YIPF5", "YLPM1", "YME1L1", "YTHDC1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZC3H14", "ZC3H4", "ZCCHC3", "ZCRB1", "ZDHHC13", "ZFPL1", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYND8", "ZNF326", "ZNF598", "ZNF622", "ZNF638", "ZNF687", "ZNHIT2", "ZPR1", "ZW10", "ZWILCH"], "leading_proteins": ["ACP6", "AFG3L2", "AP1B1", "AP1M1", "AP2M1", "AP3B1", "AP3M1", "APP", "ATAD3B", "ATP2A2", "ATP2B1", "ATP6V0A2", "AURKA", "B4GALT3", "BCL2L13", "BCLAF1", "BMS1", "BSG", "CAPN5", "CCAR1", "CDK5RAP1", "CLTB", "COPS7B", "CRNKL1", "CTNNAL1", "CTSA", "CYFIP2", "DHCR7", "DNAJA2", "DNM3", "DOCK1", "DSG2", "EARS2", "EPB41L2", "EPRS", "EWSR1", "EXOSC2", "EZR", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP2", "GNAI1", 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score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Nucleophile aminohydrolases, N-terminal [IPR029055] 6 17 2.5569091630022527 0.0105606790936645 6.097087378640777 17.820388349514563 1.118176330768516 0.343571999079937 2.960138290874742 0.7151426259133536 1.128434210928413 0.3328142150103464 1.0 0.1114021565620111 0.0233124310373507 2.2359581100408143e-05 0.0001380877092489 +Immunoglobulin-like fold [IPR013783] 12 37 2.499341134072897 0.0124424472830153 9.024271844660197 30.70631067961165 -0.0882371106398617 0.5574652875269992 4.075666983819175 5.992200349595445 1.1066442573771362 0.3307702752839019 1.0 1.0 1.0 0.6365415417537121 0.5376551094964326 +FAD/NAD(P)-binding domain superfamily [IPR036188] 6 21 2.486778535541416 0.0128905616933148 5.128640776699029 19.483009708737864 1.1388517428876976 0.3148047818604211 2.42568278788952 1.8971625900564304 0.9268276914308484 0.2996934003616133 1.0 0.0143944751365022 0.0059531349747588 0.0140312853386763 0.002448268499096 +MFS transporter superfamily [IPR036259] 4 13 2.405591164086218 0.0161463228508471 3.6432038834951457 8.356796116504855 0.9436301622284156 0.2543148229816532 1.924895010927015 2.2984539817025564 1.2198539986610124 0.2448337840515702 1.0 0.0014597322722839 8.70213798155906e-05 0.0057706709278987 0.0279038521060528 +Mitochondrial carrier domain superfamily [IPR023395] 10 24 2.2244726492984945 0.0261166606973624 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 1.0 0.1644315705571846 0.3050454458143302 0.6053596540060717 0.0094203676276074 +Glycoside hydrolase superfamily [IPR017853] 8 16 2.1946227094323425 0.0281906731493033 7.094660194174757 15.565533980582524 0.5992585613623983 0.1928722204186086 2.565315823223627 1.245604487832095 1.9386029676344616 0.2695693578719223 1.0 1.0 0.2202973788945578 2.8484663686520977e-05 2.110599340548606e-06 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 3 7 2.188409642667134 0.0286397765197126 2.813106796116505 6.104368932038835 1.6405397264547834 0.1100883340733615 1.2852875686886795 0.8042848477475721 1.100790504333474 0.1612592696854457 1.0 0.0550816697898294 0.0055563644779973 0.0025975272437437 0.0020033682110678 +Immunoglobulin-like domain superfamily [IPR036179] 5 17 2.0563149721731326 0.0397521660613104 4.480582524271845 12.427184466019416 0.4075261998509777 0.4433674298264088 2.6479725987944898 3.173316973839475 1.1756568118942026 0.3233613924696422 1.0 1.0 1.0 0.7700300254631364 0.8173151796514069 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 1 10 2.029672406444673 0.042389849524596 2.3689320388349513 6.349514563106796 0.6640264147492347 0.3307390797434538 1.7803691733569 2.1393617497725477 1.1694677427725269 0.279101120079799 1.0 0.0683810764565047 0.1336663515258769 0.0495157384890535 0.16360549489043 +PH-like domain superfamily [IPR011993] 21 64 1.9769671995753035 0.0480453379187566 16.538834951456312 55.366504854368934 -0.1721757009659374 0.6272733937475546 8.168489456557142 10.439569255029584 0.8639046053288412 0.3178368882722004 1.0 0.4441991442542667 0.8106898093526511 0.8868482039340709 0.5875131171069348 +Metallopeptidase, catalytic domain superfamily [IPR024079] 2 5 1.9630253068170835 0.0496432335539207 1.4587378640776698 4.228155339805825 1.1164526094555864 0.2711201472648778 0.9505983599630128 0.5714769615803577 0.9352765369569976 0.2609195154950394 1.0 1.0 0.1500965904253892 0.0073447144383531 0.0468003866103798 diff --git a/interpro_homologous_superfamily/metrics.json b/interpro_homologous_superfamily/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3705f6576f2c7dcefb58b6bd4688be545820aa71 --- /dev/null +++ b/interpro_homologous_superfamily/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 1023, + "title": "Average number of proteins per term", + "value": 5.0821114369501466 +} \ No newline at end of file diff --git a/interpro_homologous_superfamily/paths.json b/interpro_homologous_superfamily/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..c9044af10d7ac005a7a8c807c0cd8a0a5a196f3c --- /dev/null +++ b/interpro_homologous_superfamily/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_homologous_superfamily/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/interpro_homologous_superfamily/result.tsv b/interpro_homologous_superfamily/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..82c6eac80305c541787fa0adea2ddea1acdf0890 --- /dev/null +++ b/interpro_homologous_superfamily/result.tsv @@ -0,0 +1,184 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.9996306335141634 0.026070422299919 2 P05067 1 +Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.9996306335141634 0.026070422299919 2 P05067 1 +Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.9996306335141634 0.026070422299919 2 P05067 1 +E2 domain superfamily [IPR036176] 0.9895633067838504 2.665112650719744 0.0076962536994873 0.9996306335141634 0.026070422299919 2 P05067 1 +Nucleophile aminohydrolases, N-terminal [IPR029055] 0.7027190214921426 2.5569091630022527 0.0105606790936645 0.9999808081739736 0.0336559959900897 17 P28070,P28074,P20618,P28072,Q99436,P49721 6 +Immunoglobulin-like fold [IPR013783] 0.5665743408536403 2.4993411340728975 0.0124424472830153 0.9999972625240116 0.0375475621549401 37 P10321,O15344,Q9BY67,Q8IZA0,P30511,Q8NAT1,Q15375,P08236,P10586,Q9BX67,O75592,Q92545 12 +FAD/NAD(P)-binding domain superfamily [IPR036188] 0.6582443853475497 2.486778535541416 0.0128905616933148 0.9999982792948304 0.0387854253301795 21 Q9UHG3,Q8NB78,O95831,P00390,Q96CU9,P50336 6 +MFS transporter superfamily [IPR036259] 0.7555572916194856 2.405591164086218 0.0161463228508471 0.9999999413976628 0.0460785419000575 13 Q7L0J3,Q6NT16,P53985,Q8NHS3 4 +FAD-binding, type PCMH-like superfamily [IPR036318] 0.8948091183740704 2.2732480550852796 0.0230112358918961 0.9999999999546028 0.0601043400888823 2 Q15392 1 +FAD-binding, type PCMH, subdomain 2 [IPR016169] 0.8948091183740704 2.2732480550852796 0.0230112358918961 0.9999999999546028 0.0601043400888823 2 Q15392 1 +Dedicator of cytokinesis, C-terminal, lobe A [IPR043161] 0.890964020873384 2.2570115318948676 0.0240073541977161 0.9999999999840112 0.0621760084664902 2 Q14185 1 +Dedicator of cytokinesis, C-terminal, lobe C [IPR043162] 0.890964020873384 2.2570115318948676 0.0240073541977161 0.9999999999840112 0.0621760084664902 2 Q14185 1 +RGS domain superfamily [IPR036305] 0.8876682230156543 2.2430741507785017 0.0248920332564819 0.9999999999936772 0.0636613750534525 2 P35579 1 +Mitochondrial carrier domain superfamily [IPR023395] 0.6049861491068858 2.2244726492984945 0.0261166606973624 0.9999999999982516 0.0660594359114978 24 Q9BSK2,Q86VD7,Q70HW3,Q9UBX3,Q96H78,Q9BQT8,O43772,Q9HC21,Q9Y619,Q9Y6C9 10 +Glycoside hydrolase superfamily [IPR017853] 0.658424512376462 2.1946227094323425 0.0281906731493033 0.9999999999998026 0.0698282291325359 16 P16278,P04066,Q9BTY2,P08236,P10253,O60502,P54802,P06280 8 +Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400] 0.8310604024419772 2.188409642667134 0.0286397765197126 0.999999999999877 0.0704290658165048 7 Q8WUJ1,Q9UMX5,O15173 3 +Ferritin-like superfamily [IPR009078] 0.8728371326558649 2.1801251703206916 0.0292481844650627 0.9999999999999352 0.0715810830329166 2 Q7LG56 1 +Ribonucleotide reductase-like [IPR012348] 0.8728371326558649 2.1801251703206916 0.0292481844650627 0.9999999999999352 0.0715810830329166 2 Q7LG56 1 +Isochorismatase-like superfamily [IPR036380] 0.8662455369403983 2.152027854172158 0.0313951606208242 0.9999999999999932 0.0757482295167528 2 Q96CN7 1 +Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241] 0.8632243889041445 2.139125517370854 0.032425504311548 0.9999999999999978 0.0778668800720976 2 Q96CW5 1 +FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156] 0.9295914479574888 2.082217500232241 0.0373226074881323 1.0 0.0881778925181509 4 P00390 1 +Immunoglobulin-like domain superfamily [IPR036179] 0.6152834476619371 2.0563149721731326 0.0397521660613104 1.0 0.0921910583920858 17 P10321,Q9BY67,P30511,P10586,Q9BX67 5 +Tetraspanin, EC2 domain superfamily [IPR008952] 0.8437242515792335 2.0554837378839133 0.0398323047989266 1.0 0.0921910583920858 2 O60637 1 +ABC transporter type 1, transmembrane domain superfamily [IPR036640] 0.7114341493304953 2.029672406444673 0.042389849524596 1.0 0.0955172159992548 10 O75027 1 +Myosin S1 fragment, N-terminal [IPR008989] 0.9089194306843597 2.0035016533047383 0.0451234703155991 1.0 0.0990586054353174 4 P35579,P35580 2 +Mannose-6-phosphate receptor binding domain superfamily [IPR009011] 0.905615302303393 1.990866266504577 0.0464955916996723 1.0 0.1016345946768478 4 P20645 1 +PH-like domain superfamily [IPR011993] 0.4393681918760441 1.976967199575303 0.0480453379187566 1.0 0.1043532498744969 64 P26038,Q9Y5S2,Q92888,Q8IZD4,P05067,Q06481,Q96JJ3,A1A4S6,O75116,Q9NZM3,Q96TA1,Q13464,Q9UQ16,P11274,P31749,P49792,Q9H4L5,Q6WCQ1,Q6IN85,Q01082,P31751 21 +Metallopeptidase, catalytic domain superfamily [IPR024079] 0.8610112773044685 1.963025306817083 0.0496432335539207 1.0 0.1070659439380295 5 P42892,P52888 2 +Lamin tail domain superfamily [IPR036415] 0.9123626373626376 1.9269164766198033 0.0539900397723283 1.0 0.1145888188528876 3 P02545,Q03252 2 +Zinc finger, ZZ-type superfamily [IPR043145] 0.8135127712166959 1.9247018500713953 0.0542666689225133 1.0 0.114937478897994 2 P46939 1 +Kringle-like fold [IPR013806] 0.8041746772864553 1.8839996919566135 0.0595650171367001 1.0 0.1222767577701658 2 P11717 1 +Fibronectin type II domain superfamily [IPR036943] 0.8041746772864553 1.8839996919566135 0.0595650171367001 1.0 0.1222767577701658 2 P11717 1 +EB1, C-terminal domain superfamily [IPR036133] 0.7978577313924721 1.8563951936210343 0.0633972493183305 1.0 0.1284265070349548 2 Q15555 1 +Zinc finger, RING/FYVE/PHD-type [IPR013083] 0.4209546449143819 1.801288114054231 0.0716574802776441 1.0 0.1412738567764833 65 Q9Y4X5,P19474,O15344,O95155,Q14527,O75592,Q15075,O60858,P14373,Q9UPT9,O96028,Q9Y2K7,Q13049,Q99590 14 +Porin domain superfamily [IPR023614] 0.8545283315463459 1.7937142338709169 0.0728587922315089 1.0 0.14283023766657 4 P21796 1 +L27 domain superfamily [IPR036892] 0.8150128151352414 1.780042291612069 0.0750690397004245 1.0 0.1462773859305415 5 Q14168,Q8N3R9,O14936 3 +Glycosyl hydrolase, all-beta [IPR013780] 0.7039331019584887 1.7456367455590944 0.0808740929008322 1.0 0.1543548452193123 8 Q9BTY2,P04066,P10253,P06280 4 +Fibronectin type III superfamily [IPR036116] 0.7230994613683847 1.72685524601345 0.0841936636941071 1.0 0.1595002184427253 7 Q15375,O15344,P10586 3 +Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236] 0.7643504531722036 1.7090895446258176 0.087434363980519 1.0 0.1646522734274303 2 P42356 1 +Class II aldolase/adducin N-terminal domain superfamily [IPR036409] 0.7616039549574273 1.6969549062952731 0.0897051862312885 1.0 0.1674605940047594 2 Q9UEY8 1 +Ribosomal protein L37ae/L37e [IPR011331] 0.74512496566877 1.6239798857241667 0.1043801014680532 1.0 0.1863540031445348 2 P61513 1 +FIP-RBD, C-terminal domain superfamily [IPR037245] 0.741279868168083 1.6069142726023324 0.1080731750392103 1.0 0.1919424619185974 2 Q8IUD2 1 +P-type ATPase, cytoplasmic domain N [IPR023299] 0.7327228967970489 1.5935355599975791 0.1110400975612098 1.0 0.1951787281874873 6 P16615 1 +P-type ATPase, A domain superfamily [IPR008250] 0.7327228967970489 1.5935355599975791 0.1110400975612098 1.0 0.1951787281874873 6 P16615 1 +P-type ATPase, transmembrane domain superfamily [IPR023298] 0.7327228967970489 1.5935355599975791 0.1110400975612098 1.0 0.1951787281874873 6 P16615 1 +Translation initiation factor IF-2, domain 3 superfamily [IPR036925] 0.7322164240593204 1.5666376314022687 0.1171994165517571 1.0 0.2032118697160128 2 P46199 1 +Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097] 0.7242639521483516 1.5579162412450842 0.1192531046464844 1.0 0.2057266881169537 6 Q9UIQ6,P55786 2 +Peptidase M4/M1, CTD superfamily [IPR027268] 0.7242639521483516 1.5579162412450842 0.1192531046464844 1.0 0.2057266881169537 6 Q9UIQ6,P55786 2 +Ribosomal protein L24e/L24 superfamily [IPR038630] 0.7267234276297689 1.5421960385014823 0.1230259624634679 1.0 0.2101094484142366 2 Q9UHA3 1 +B30.2/SPRY domain superfamily [IPR043136] 0.6079182396567849 1.5207501202792553 0.1283225559075478 1.0 0.2184259146313168 10 P19474,O15344 2 +Alkaline-phosphatase-like, core domain superfamily [IPR017850] 0.8021978021978027 1.4999576500058216 0.1336253730250041 1.0 0.2252038823798668 3 Q5H8A4,P15586 2 +Tetratricopeptide-like helical domain superfamily [IPR011990] 0.3823138118401853 1.4951328740217311 0.1348797678589908 1.0 0.2265714327089451 92 Q5R3I4,O00231,Q96RK4,O75153,A0AVF1,O15287,P49321,Q9UJX3,O75718,P61201,O00411,Q6ZXV5,Q9BQ70,Q9H7Z3,Q6PGP7,Q96EK5,Q6DKK2,Q6N069 18 +Integrin alpha, N-terminal [IPR028994] 0.7151881351277088 1.4908027346554398 0.1360132936031362 1.0 0.2277276585204718 2 P17301 1 +Zinc finger, RanBP2-type superfamily [IPR036443] 0.647610944119114 1.4884149675770164 0.1366414917289451 1.0 0.2284056307822073 8 P98175,P35637,P49792,P52756,Q01844 5 +ISWI, HAND domain superfamily [IPR036306] 0.6954133479813198 1.4025491716928022 0.1607513177976449 1.0 0.2622784658803681 2 P28370 1 +Homeobox-like domain superfamily [IPR009057] 0.4870485432813873 1.3757278202830523 0.1689059154490912 1.0 0.2747070771135459 19 Q8NB78,P28370,Q13330,Q96KC8,Q96G23 5 +Alpha/Beta hydrolase fold [IPR029058] 0.4593781737359546 1.346546421136278 0.1781263600707818 1.0 0.2874184011867663 28 Q9HB40,P42785,P07099,P50897,Q9UMR5,P10619,Q8NCC3 7 +Ribosomal protein L10e/L16 superfamily [IPR036920] 0.681406207085961 1.3399820432682468 0.1802511829141848 1.0 0.2903889135767104 2 P27635 1 +von Willebrand factor A-like domain superfamily [IPR036465] 0.4824331175636111 1.337577127084034 0.1810343247163865 1.0 0.2911920034353199 18 Q71SY5,P12956,Q15437 3 +Alpha-catenin/vinculin-like superfamily [IPR036723] 0.7374489595998857 1.3320313571032998 0.1828498846767896 1.0 0.2929731273377715 4 Q9UBT7 1 +Oxysterol-binding protein superfamily [IPR037239] 0.6564318205937275 1.2701643146512247 0.2040261061161021 1.0 0.3220967693777353 6 Q9H4L5 1 +Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695] 0.6646525679758262 1.265173988611413 0.2058089646327749 1.0 0.323911647414352 2 P54136 1 +Peptidase M41-like [IPR037219] 0.6638286185113931 1.2614973734562842 0.2071297057026968 1.0 0.3249903204507038 2 Q9Y4W6 1 +Ribosomal protein L22/L17 superfamily [IPR036394] 0.657511672617408 1.2333220722211666 0.2174556261349729 1.0 0.3401484794129623 2 Q9NWU5 1 +Histidine phosphatase superfamily [IPR029033] 0.6754584468733541 1.211602432847339 0.2256646028523228 1.0 0.3497801344211004 5 Q9NPH0 1 +LEM/LEM-like domain superfamily [IPR011015] 0.634038443208601 1.1748192386504162 0.2400670415314691 1.0 0.3660038502037153 6 P42166,Q86XL3,Q9Y2U8 3 +Regulatory factor, effector binding domain superfamily [IPR011256] 0.7186813186813195 1.1718670115605183 0.2412504532703132 1.0 0.3672607346659679 3 Q9Y5Z4,Q9Y6I9 2 +NAP-like superfamily [IPR037231] 0.6949926271104224 1.163289815191387 0.2447119365186645 1.0 0.3719766880514024 4 Q99733,Q01105 2 +GTP-binding protein, orthogonal bundle domain superfamily [IPR023179] 0.7123626373626382 1.14711379102564 0.2513345948324965 1.0 0.3792260922030147 3 Q9BT17,Q9NVN8 2 +STAT transcription factor, N-terminal domain superfamily [IPR036535] 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.383654925388154 2 P42224 1 +STAT transcription factor, coiled coil [IPR015988] 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.383654925388154 2 P42224 1 +STAT transcription factor, DNA-binding, N-terminal [IPR012345] 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.383654925388154 2 P42224 1 +Kinesin motor domain superfamily [IPR036961] 0.4482406868177204 1.136446007271515 0.2557699502587693 1.0 0.383654925388154 21 P35579,P35580,P33176,Q9Y496,O94832,Q7Z406,O95235,Q02241,P52732,O95239,Q14807 11 +High mobility group box domain superfamily [IPR036910] 0.5129007299016555 1.13348188224586 0.2570119453892905 1.0 0.3846606016362772 13 O96028,P26583,P17480 3 +Cadherin-like superfamily [IPR015919] 0.6562149289367434 1.1327338708256405 0.2573260292961699 1.0 0.3846606016362772 5 P19022,Q9BQT9,O60245 3 +p53-like tetramerisation domain superfamily [IPR036674] 0.6336171381488545 1.12704114526228 0.2597250851682369 1.0 0.3873159797771229 2 Q13043 1 +Concanavalin A-like lectin/glucanase domain superfamily [IPR013320] 0.445282664208419 1.1165874371545237 0.2641707655790977 1.0 0.3933721880457306 21 Q9BQT9,P19474,O15344 3 +Aldehyde dehydrogenase, C-terminal [IPR016163] 0.5170397436391612 1.0884392131829923 0.276401257934479 1.0 0.4059384092033208 11 P30837 1 +Aldehyde/histidinol dehydrogenase [IPR016161] 0.5170397436391612 1.0884392131829923 0.276401257934479 1.0 0.4059384092033208 11 P30837 1 +Aldehyde dehydrogenase, N-terminal [IPR016162] 0.5170397436391612 1.0884392131829923 0.276401257934479 1.0 0.4059384092033208 11 P30837 1 +DUSP-like superfamily [IPR035927] 0.6972465097820897 1.0880392461428492 0.2765777822235724 1.0 0.4059384092033208 3 Q86UV5 1 +CRAL-TRIO lipid binding domain superfamily [IPR036865] 0.6932771832252811 1.0725673900191417 0.2834652625874814 1.0 0.4142642337528478 3 Q07960 1 +SNARE [IPR010989] 0.5743559746779824 1.0657484905685968 0.2865373512055278 1.0 0.4169668709576884 7 O15400,O43752,O60499 3 +HR1 repeat superfamily [IPR036274] 0.6146663004668984 1.043284721187825 0.2968164452443369 1.0 0.4294812213365723 2 Q16513 1 +SMCs flexible hinge superfamily [IPR036277] 0.632049966208721 1.034086030796029 0.3010959461649496 1.0 0.4341990174152921 5 O95347,Q9UQE7,Q9NTJ3 3 +NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064] 0.6832417582417594 1.0335421696926197 0.3013502466909652 1.0 0.4341990174152921 3 Q9NRA0,Q53H12 2 +Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438] 0.6832417582417594 1.0335421696926197 0.3013502466909652 1.0 0.4341990174152921 3 Q9NRA0,Q53H12 2 +HIT-like superfamily [IPR036265] 0.652483275487963 0.9954875705230436 0.3194991865186196 1.0 0.4539550941785387 4 Q9NQE9 1 +SH3-like domain superfamily [IPR036028] 0.3820138503899377 0.9943700712600734 0.32004273322244 1.0 0.4540966936013261 37 Q9Y5X1,Q96RU3,Q14168,Q8N3R9,Q9UQB8,Q13813,Q14185 7 +EF-hand domain pair [IPR011992] 0.3500039752554433 0.963416327574236 0.3353386357219159 1.0 0.4738279341761325 55 Q9BRK5,Q02818,P12814,Q14257,Q9NZM3,O75071,O43707,Q8IYU8,Q9BPX6,Q13813,P80303,P46939 12 +SKP1/BTB/POZ domain superfamily [IPR011333] 0.5473098162876712 0.9456622844122304 0.3443208650895375 1.0 0.4851794008079846 7 Q4G0X4 1 +Nop, C-terminal domain [IPR042239] 0.6492290356571275 0.9025737105544182 0.3667521844372983 1.0 0.5076961903644873 3 Q8WWY3 1 +Nop domain superfamily [IPR036070] 0.6492290356571275 0.9025737105544182 0.3667521844372983 1.0 0.5076961903644873 3 Q8WWY3 1 +Cyclic nucleotide-binding-like [IPR018490] 0.5974013388554889 0.8941240976351105 0.3712554973489921 1.0 0.51254301455873 5 Q9Y4G8 1 +K Homology domain, type 1 superfamily [IPR036612] 0.3996251029087261 0.8843854354459473 0.3764881824848056 1.0 0.5155922499089105 27 Q06787,Q07666,Q9UNW9,Q9NZI8,Q96PU8,P51114,Q9NQT5,Q13868,Q9Y6M1,P51116,Q92945,Q9Y2W6,Q13601 13 +Methylthiotransferase, N-terminal domain superfamily [IPR038135] 0.5773139247459417 0.8806246688788618 0.3785210019820666 1.0 0.5163026467035389 2 Q96SZ6 1 +Radical SAM, alpha/beta horseshoe [IPR023404] 0.5773139247459417 0.8806246688788618 0.3785210019820666 1.0 0.5163026467035389 2 Q96SZ6 1 +p53-like transcription factor, DNA-binding [IPR008967] 0.6337912087912101 0.844020664322525 0.3986578584318141 1.0 0.5423231239039173 3 P42224,P40763 2 +NTF2-like domain superfamily [IPR032710] 0.519534460578188 0.8239350904698453 0.4099764406331541 1.0 0.5536783580622361 7 Q13555 1 +Zinc-binding ribosomal protein [IPR011332] 0.626923076923078 0.8181989099643588 0.4132436174814931 1.0 0.5569805279098385 3 P61927,P61513 2 +Galactose-binding-like domain superfamily [IPR008979] 0.46430784946994 0.8168846217499225 0.4139943668534398 1.0 0.5572582069619328 11 P16278,Q15375,O75592,P08236 4 +AH/BAR domain superfamily [IPR027267] 0.3946817356091735 0.7686296884776457 0.4421131758396059 1.0 0.5869437335140981 18 Q9UQB8,Q9Y5X1,Q96RU3 3 +C2 domain superfamily [IPR035892] 0.3801745569375844 0.7667859651293294 0.4432087822630965 1.0 0.5869437335140981 28 Q9NZM3,Q96PE3,Q96N67,O14976,O15484,P11274,Q14185 7 +DNA/RNA polymerase superfamily [IPR043502] 0.5650860037452896 0.766284820212447 0.4435068484911024 1.0 0.5869437335140981 5 O00411 1 +CH domain superfamily [IPR036872] 0.3730290783376666 0.762349697327243 0.4458513201079084 1.0 0.5885237425424391 30 P12814,Q15555,Q86VI3,O43707,Q5M775,Q96ED9,P46939 7 +GYF-like domain superfamily [IPR035445] 0.6099994988065428 0.7552723415728692 0.4500855905193086 1.0 0.5912470179295907 3 O95400 1 +PX domain superfamily [IPR036871] 0.4320732567926289 0.7459941160123988 0.4556709694422962 1.0 0.5953402321066016 14 Q9Y5X1,Q53T59,Q96L92,O95219,Q9Y5X2 5 +PDZ superfamily [IPR036034] 0.3702631889316031 0.7418017297378826 0.4582074724121336 1.0 0.5978906177010367 30 Q96L92,Q9Y4G8,Q14168,P57105,Q8N3R9,O14936 6 +Calpain large subunit, domain III superfamily [IPR036213] 0.5919576312332964 0.6894691235228179 0.4905280972263874 1.0 0.6320028255196403 3 O15484 1 +MHC classes I/II-like antigen recognition protein [IPR011162] 0.5384784379131797 0.6640198687616927 0.5066775945552513 1.0 0.6479139740375276 5 P30511,P10321 2 +MHC class I-like antigen recognition-like superfamily [IPR037055] 0.5384784379131797 0.6640198687616927 0.5066775945552513 1.0 0.6479139740375276 5 P30511,P10321 2 +Moesin tail domain superfamily [IPR008954] 0.5823565411671765 0.6550796698300458 0.512416460713812 1.0 0.6519925862067533 3 P26038 1 +Ubiquitin-like domain superfamily [IPR029071] 0.3248550826304487 0.6457681238834088 0.5184295345414363 1.0 0.6577229258715345 47 P46379 1 +Glutathione S-transferase, C-terminal domain superfamily [IPR036282] 0.3844315909837438 0.6392269841946197 0.5226752802068231 1.0 0.6609354902986156 17 Q13505 1 +Guanylate-binding protein, C-terminal domain superfamily [IPR036543] 0.5108486679483568 0.606157733921665 0.544410016217171 1.0 0.6775321734673552 2 Q8NHH9 1 +PapD-like superfamily [IPR008962] 0.561948609577662 0.5836721608030339 0.559440900675491 1.0 0.6920290706058372 3 Q8NHP6 1 +Histone deacetylase domain superfamily [IPR037138] 0.5020598736610726 0.5720723475786397 0.5672729620269941 1.0 0.700024415143082 2 Q92769 1 +Death-like domain superfamily [IPR011029] 0.5384829634988266 0.5682574369789825 0.5698601756269417 1.0 0.7023698309233269 4 Q7Z434 1 +CRIB domain superfamily [IPR036936] 0.5001373249107317 0.5647042724088714 0.5722749277598385 1.0 0.704497293740451 2 Q13177 1 +Dbl homology (DH) domain superfamily [IPR035899] 0.4568058618832359 0.5608905666987682 0.5748721411813631 1.0 0.7059954386897171 7 P11274,Q9NZM3 2 +Zinc finger, PARP-type superfamily [IPR036957] 0.4982147761603859 0.5573690652490848 0.5772752966767001 1.0 0.7080966768588299 2 P49916 1 +Protein-tyrosine phosphatase-like [IPR029021] 0.4099978137352028 0.5356807961779904 0.5921791780056218 1.0 0.718623130604687 10 O14976,P10586 2 +SAP domain superfamily [IPR036361] 0.4029640842334441 0.5314869859152722 0.5950813572839417 1.0 0.721289370262408 12 P12956,Q9NWH9 2 +Translation elongation factor eEF-1beta-like superfamily [IPR036219] 0.4907992309804909 0.5293945452609559 0.5965317813531499 1.0 0.7221065021622565 2 P29692 1 +Catenin binding domain superfamily [IPR027397] 0.5379637784219328 0.5031963396127432 0.6148262380745793 1.0 0.7382244619134912 3 P19022 1 +Mss4-like superfamily [IPR011057] 0.4751441911562702 0.472122180158039 0.6368395816008556 1.0 0.7575428976484596 2 Q7Z7K6 1 +Rho GTPase activation protein [IPR008936] 0.3855010835861801 0.4643725955280723 0.6423808206529049 1.0 0.7623614611692827 13 P11274,Q86VI3,A1A4S6,Q07960 4 +Alpha/beta knot methyltransferases [IPR029028] 0.4630595990112555 0.429733567234305 0.6673894627320351 1.0 0.7874733799018131 2 Q9HC36 1 +tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026] 0.4630595990112555 0.429733567234305 0.6673894627320351 1.0 0.7874733799018131 2 Q9HC36 1 +Papain-like cysteine peptidase superfamily [IPR038765] 0.3343864919425706 0.4224680432069597 0.6726834215454953 1.0 0.7909829198172893 26 Q96K76,P17655,Q86UV5,Q8NB14,Q93009,O15484,Q9UPT9 7 +Nucleotide-diphospho-sugar transferases [IPR029044] 0.3335881169129225 0.4070379665669394 0.6839801033767965 1.0 0.8015024579088921 25 P15291,O60512,Q68CQ7 3 +Six-hairpin glycosidase-like superfamily [IPR012341] 0.4117500515596032 0.3899595731674442 0.696566441002042 1.0 0.8147673602023882 7 Q9NS86 1 +Ribosomal protein L13 superfamily [IPR036899] 0.4507003570447634 0.3881942290564076 0.6978723035187699 1.0 0.8147673602023882 2 Q9BYD1 1 +Zinc finger, FYVE/PHD-type [IPR011011] 0.3245893090544535 0.3850872168002401 0.7001727986081887 1.0 0.8156951335579298 28 Q15075,Q9BZ95,Q9UIF9,Q96L73,Q9NRL2,O96028,Q8WUB8,Q9Y2K7,Q14839,Q9UIG0 10 +PWI domain superfamily [IPR036483] 0.4996134873534651 0.3841383925372961 0.7008758772213297 1.0 0.8156951335579298 3 O43395 1 +Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919] 0.448777808294416 0.3819074523331101 0.702530012370373 1.0 0.8157641346820563 2 Q6DKI1 1 +Metalloenzyme, LuxS/M16 peptidase-like [IPR011249] 0.4079586779670796 0.3765602340441724 0.7065004445618184 1.0 0.8191679179380414 7 P22695,Q10713,Q5JRX3 3 +Translation elongation factor EF1B/ribosomal protein S6 [IPR014717] 0.4909340659340676 0.3591204172462471 0.7195050082715055 1.0 0.8296220248049904 3 P29692,P82932 2 +Translation protein SH3-like domain superfamily [IPR008991] 0.3653634361233604 0.349482945792948 0.7267267719451733 1.0 0.8343899974185324 11 P61254,P63241,P50914,Q5T653,Q02878,P49406,P62917,O00267,Q96A35,P46778 10 +Nucleotidyltransferase superfamily [IPR043519] 0.3913641364136505 0.3200620267232771 0.7489213109769084 1.0 0.8569871377286099 7 Q5TAX3,Q9NVV4,Q12905,Q12906,Q96SI9,P51003 6 +Helix hairpin bin domain superfamily [IPR029012] 0.4281790716835991 0.3177241333577256 0.7506942033062154 1.0 0.8580560558460987 2 Q9ULR0 1 +Dynein heavy chain, domain 2, N-terminal [IPR042222] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8684042389970016 2 Q8NCM8 1 +Dynein heavy chain AAA lid domain superfamily [IPR042219] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8684042389970016 2 Q8NCM8 1 +Dynein heavy chain, linker, subdomain 3 [IPR042228] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8684042389970016 2 Q8NCM8 1 +Dynein heavy chain, C-terminal domain, barrel region [IPR043160] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8684042389970016 2 Q8NCM8 1 +Dynein heavy chain, AAA1 domain, small subdomain [IPR043157] 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.8684042389970016 2 Q8NCM8 1 +CAP Gly-rich domain superfamily [IPR036859] 0.4654609843894143 0.2904102471418421 0.7715024052613431 1.0 0.8720960890412751 3 Q14203 1 +SNF2-like, N-terminal domain superfamily [IPR038718] 0.3329447667380133 0.2794571071676878 0.7798940507395886 1.0 0.8777025455518143 15 Q9UNY4,P28370,Q14527,P51532,Q9H4L7,Q9NRZ9,Q2NKX8,O14646,Q14839 9 +Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155] 0.4122493820378954 0.2723559304315974 0.7853483546776621 1.0 0.8819005124426436 2 Q9H267 1 +Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091] 0.3922144264383029 0.2540117706089591 0.7994864646455149 1.0 0.8948300364686671 6 O75592 1 +DNA/RNA non-specific endonuclease superfamily [IPR044929] 0.4009887393573154 0.2426973461696238 0.8082398634501555 1.0 0.8967540346296775 2 Q14249 1 +His-Me finger superfamily [IPR044925] 0.4009887393573154 0.2426973461696238 0.8082398634501555 1.0 0.8967540346296775 2 Q14249 1 +Ribokinase-like [IPR029056] 0.4448705364770237 0.2404629451150249 0.809971386117128 1.0 0.8967540346296775 3 P55263 1 +Sterile alpha motif/pointed domain superfamily [IPR013761] 0.3357214207028602 0.2309598273297415 0.8173460114412916 1.0 0.902964330134386 10 Q13136 1 +Zinc finger, CCHC-type superfamily [IPR036875] 0.3802204987484867 0.2218174892443061 0.8244559641451814 1.0 0.9032405070295034 6 Q5TAX3,Q6ZN17 2 +Galactose mutarotase-like domain superfamily [IPR011013] 0.4007038142922224 0.2215560927841649 0.8246594658509836 1.0 0.9032405070295034 5 P10253 1 +HotDog domain superfamily [IPR029069] 0.3643112455320371 0.1825056778767227 0.8551858988889351 1.0 0.9306969942163624 6 Q9NPJ3,O00154,Q9Y305,O14734,Q8WUY1 5 +Malonyl-CoA ACP transacylase, ACP-binding [IPR016036] 0.3707772589947781 0.1735994149706064 0.8621802918254529 1.0 0.9333443794046966 2 Q8IVS2 1 +Acyl transferase domain superfamily [IPR001227] 0.3707772589947781 0.1735994149706064 0.8621802918254529 1.0 0.9333443794046966 2 Q8IVS2 1 +GAR domain superfamily [IPR036534] 0.369678659708864 0.1713822620664267 0.8639232012521407 1.0 0.9342425315866172 2 Q9UPN3 1 +Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037] 0.3674814611370466 0.1670108455712655 0.8673615152501173 1.0 0.9369702535384056 2 Q10567 1 +ARID DNA-binding domain superfamily [IPR036431] 0.3912087912087929 0.1363169687292378 0.8915707099931478 1.0 0.950080037836448 3 Q68CP9,O14497 2 +Chromo-like domain superfamily [IPR016197] 0.3109521188772615 0.1317390952393024 0.8951906614641729 1.0 0.952944897687668 9 P45973,P83916,Q9P2D1,Q9HC52,Q13185,O14646,Q14839,Q9UBU8 8 +RuvA domain 2-like [IPR010994] 0.3868131868131888 0.1295158266964063 0.8969495025317866 1.0 0.9537105121353832 3 Q7KZ85,Q14807 2 +RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792] 0.3837912087912106 0.1249919548100914 0.9005299195217056 1.0 0.95564533990737 3 Q9Y4E8,O00442 2 +Zinc finger, CCCH-type superfamily [IPR036855] 0.3326917789386943 0.1165226725093227 0.9072383184227008 1.0 0.9598810498967534 6 Q9UPT8,Q96QC0,Q9NW64,Q8WU90,Q86VM9 5 +RNA polymerase Rpb1, funnel domain superfamily [IPR038120] 0.376098901098903 0.1140314759415882 0.9092128419843148 1.0 0.9598810498967534 3 O14802,O95602 2 +RNA polymerase Rpb1, clamp domain superfamily [IPR044893] 0.376098901098903 0.1140314759415882 0.9092128419843148 1.0 0.9598810498967534 3 O14802,O95602 2 +RNA polymerase Rpb1, domain 3 superfamily [IPR042102] 0.376098901098903 0.1140314759415882 0.9092128419843148 1.0 0.9598810498967534 3 O14802,O95602 2 +Ribosomal protein L2, domain 2 [IPR014722] 0.2983471074380228 0.1111325227513778 0.9115112590444658 1.0 0.9610605412631142 13 P61254,P50914,O95714,P62701,Q5T653,Q92917,Q02878,P62917,O00267,Q96A35,O60870,P63241 12 +Histidine kinase/HSP90-like ATPase superfamily [IPR036890] 0.2976321585903102 0.110252686605194 0.9122089790483714 1.0 0.9610605412631142 11 P54277,Q12931,Q15120,A6NHR9,P11388,P08238,Q15118,P14625,P07900,O14874 10 +Formin, FH2 domain superfamily [IPR042201] 0.3569661995053683 0.103483168760051 0.9175795071563057 1.0 0.9640247748321203 4 O60610,Q9NSV4,Q9Y613 3 +Chaperone J-domain superfamily [IPR036869] 0.2745688978820756 0.098480567389602 0.921550701920672 1.0 0.9640247748321203 20 Q99615,Q99543,O14976,Q96KC8,Q9NXW2,O60884,Q13217,Q8IXB1,Q9UGP8,O75165 10 +SCP2 sterol-binding domain superfamily [IPR036527] 0.3640109890109911 0.098394561591256 0.9216189929480096 1.0 0.9640247748321203 3 P22307,Q6YN16 2 +Ribosomal protein L23/L15e core domain superfamily [IPR012678] 0.3423076923076942 0.0749984171116681 0.940215971309356 1.0 0.9743732012050264 3 P62847,P61313 2 +Aspartate decarboxylase-like domain superfamily [IPR009010] 0.3412087912087934 0.0739667094629078 0.941036874673085 1.0 0.9743732012050264 3 P46459,Q8NB90 2 +FF domain superfamily [IPR036517] 0.3174075596611372 0.0549553157490842 0.956174062827791 1.0 0.9848160805326892 3 O14776 1 +BRK domain superfamily [IPR037259] 0.3104395604395625 0.0505142686837595 0.9597125791556352 1.0 0.9867195663077536 3 P51532,Q9P2D1 2 +Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001] 0.2807258729722351 0.0436822458189129 0.9651576914910702 1.0 0.9889405402044404 6 Q05639,P15170,P41091,P49411,Q9Y450 5 +DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921] 0.2892202237239694 0.0429522607395587 0.9657395891146 1.0 0.9889405402044404 5 P40938 1 +Cullin homology domain superfamily [IPR036317] 0.277426450371198 0.0404634021911382 0.9677236839527052 1.0 0.9894683396557764 6 Q93034,Q13618,Q9UJX6,Q13620,Q13617 5 +Band 7/SPFH domain superfamily [IPR036013] 0.2537351235337979 0.0244515690297453 0.9804924144664908 1.0 0.9947442493895442 8 O75955 1 +FERM superfamily, second domain [IPR035963] 0.2393545948648566 0.0025749837598167 0.9979454624841736 1.0 1.0 9 Q96AC1,P15311,O43491,P26038 4 diff --git a/interpro_homologous_superfamily/selections.json b/interpro_homologous_superfamily/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..14d15960908e0ca7e45ea4ffbffdb075470397a6 --- /dev/null +++ b/interpro_homologous_superfamily/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["14-3-3 domain superfamily [IPR036815]", "2Fe-2S ferredoxin-like superfamily [IPR036010]", "30s ribosomal protein S13, C-terminal [IPR027437]", "4'-phosphopantetheinyl transferase domain superfamily [IPR037143]", "5'-3' exonuclease, C-terminal domain superfamily [IPR036279]", "50S ribosomal protein L10, insertion domain superfamily [IPR043164]", "50S ribosomal protein L30e-like [IPR029064]", "6-phosphogluconate dehydrogenase, domain 2 [IPR013328]", "6-phosphogluconate dehydrogenase-like, C-terminal domain superfamily [IPR008927]", "ABC transporter type 1, transmembrane domain superfamily [IPR036640]", "ACP-like superfamily [IPR036736]", "ADF-H/Gelsolin-like domain superfamily [IPR029006]", "AF1104-like superfamily [IPR036075]", "AH/BAR domain superfamily [IPR027267]", "AICAR transformylase, duplicated domain superfamily [IPR024051]", "AICAR transformylase, insert domain superfamily [IPR024050]", "AMP-binding enzyme, C-terminal domain superfamily [IPR045851]", "AN1-like Zinc finger [IPR035896]", "ANL, N-terminal domain [IPR042099]", "ANTH domain superfamily [IPR014712]", "AP-2 complex subunit mu, C-terminal superfamily [IPR036168]", "ARFGAP/RecO-like zinc finger [IPR037278]", "ARID DNA-binding domain superfamily [IPR036431]", "ATP synthase subunit alpha, N-terminal domain-like superfamily [IPR023366]", "ATP synthase, F0 complex, subunit A superfamily [IPR035908]", "ATP synthase, F0 complex, subunit D superfamily, mitochondrial [IPR036228]", "ATP synthase, F1 complex, gamma subunit superfamily [IPR035968]", "ATP synthase, alpha subunit, C-terminal domain superfamily [IPR038376]", "ATP synthase-coupling factor 6 superfamily, mitochondrial [IPR036204]", "ATP-NAD kinase, PpnK-type, C-terminal [IPR017437]", "ATP-grasp fold, subdomain 1 [IPR013815]", "ATP12 orthogonal Bundle domain superfamily [IPR023335]", "ATP12, ATP synthase F1-assembly protein, N-terminal [IPR042272]", "ATP:guanido phosphotransferase, N-terminal domain superfamily [IPR036802]", "ATPase, F1/V1 complex, beta/alpha subunit, C-terminal [IPR024034]", "ATPase, F1/V1/A1 complex, alpha/beta subunit, N-terminal domain superfamily [IPR036121]", "ATPase, V1 complex, subunit H, C-terminal domain superfamily [IPR038497]", "ATPase, nucleotide binding domain [IPR043129]", "Acetylglutamate kinase-like superfamily [IPR036393]", "Aconitase, domain 2 [IPR015932]", "Aconitase, iron-sulfur domain [IPR036008]", "Aconitase/3-isopropylmalate dehydratase large subunit, alpha/beta/alpha, subdomain 1/3 [IPR015931]", "Aconitase/3-isopropylmalate dehydratase, swivel [IPR015928]", "Actin-crosslinking [IPR008999]", "Actin-related protein 2/3 complex subunit 3 superfamily [IPR036753]", "Activator of Hsp90 ATPase, Aha1 [IPR036338]", "Acyl transferase domain superfamily [IPR001227]", "Acyl transferase/acyl hydrolase/lysophospholipase [IPR016035]", "Acyl-CoA N-acyltransferase [IPR016181]", "Acyl-CoA binding protein superfamily [IPR035984]", "Acyl-CoA dehydrogenase-like, C-terminal [IPR036250]", "Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily [IPR009100]", "Acyl-CoA dehydrogenase/oxidase, N-terminal domain superfamily [IPR037069]", "Acyl-CoA thioester hydrolase/BAAT, N-terminal [IPR042490]", "Acyl-CoA thioesterase, double hotdog domain [IPR042171]", "Adenine nucleotide alpha hydrolase-like domains [IPR023382]", "Adenosylhomocysteinase-like superfamily [IPR042172]", "Adenylate cyclase-associated CAP, C-terminal superfamily [IPR036223]", "Adenylate cyclase-associated CAP, N-terminal domain superfamily [IPR036222]", "Adenylate kinase, active site lid domain superfamily [IPR036193]", "Adenylosuccinate synthetase, domain 1 [IPR042109]", "Adenylosuccinate synthetase, domain 2 [IPR042110]", "Adenylosuccinate synthetase, domain 3 [IPR042111]", "Alanine-tRNA ligase, class IIc, anti-codon-binding domain superfamily [IPR018162]", "Alba-like domain superfamily [IPR036882]", "Aldehyde dehydrogenase, C-terminal [IPR016163]", "Aldehyde dehydrogenase, N-terminal [IPR016162]", "Aldehyde/histidinol dehydrogenase [IPR016161]", "Aldolase-type TIM barrel [IPR013785]", "Alkaline-phosphatase-like, core domain superfamily [IPR017850]", "Allosteric substrate binding domain superfamily [IPR029009]", "Alpha-D-phosphohexomutase, C-terminal domain superfamily [IPR036900]", "Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III [IPR016055]", "Alpha-catenin/vinculin-like superfamily [IPR036723]", "Alpha-glycerophosphate oxidase, C-terminal domain superfamily [IPR038299]", "Alpha-helical ferredoxin [IPR009051]", "Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain superfamily [IPR036784]", "Alpha-ketoglutarate-dependent dioxygenase AlkB-like superfamily [IPR037151]", "Alpha-macroglobulin, receptor-binding domain superfamily [IPR036595]", "Alpha/Beta hydrolase fold [IPR029058]", "Alpha/beta knot methyltransferases [IPR029028]", "Amidase signature (AS) superfamily [IPR036928]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding domain, subdomain 2 [IPR020751]", "Aminoacyl-tRNA synthetase, class I, anticodon-binding superfamily [IPR008925]", "Aminoacyl-tRNA synthetase, class Ia, anticodon-binding [IPR009080]", "Aminopeptidase N-like , N-terminal domain superfamliy [IPR042097]", "Aminotransferase-like, PLP-dependent enzymes [IPR036038]", "Amyloidogenic glycoprotein, amyloid-beta peptide superfamily [IPR037071]", "Amyloidogenic glycoprotein, copper-binding domain superfamily [IPR036669]", "Amyloidogenic glycoprotein, heparin-binding domain superfamily [IPR036454]", "Ankyrin repeat-containing domain superfamily [IPR036770]", "Annexin superfamily [IPR037104]", "Anticodon-binding domain superfamily [IPR036621]", "Antifreeze-like/N-acetylneuraminic acid synthase C-terminal domain superfamily [IPR036732]", "ApaG domain superfamily [IPR036767]", "Apolipoprotein C-I domain superfamily [IPR043081]", "Apyrase superfamily [IPR036258]", "ArfGAP domain superfamily [IPR038508]", "Arginyl tRNA synthetase N-terminal domain superfamily [IPR036695]", "Armadillo-like helical [IPR011989]", "Armadillo-type fold [IPR016024]", "Arp2/3 complex subunit 2/4 [IPR034666]", "Arrestin, N-terminal [IPR014753]", "Arrestin-like, C-terminal [IPR014752]", "Aspartate decarboxylase-like domain superfamily [IPR009010]", "Aspartate/ornithine carbamoyltransferase superfamily [IPR036901]", "Aspartic peptidase domain superfamily [IPR021109]", "Aspartyl/glutamyl-tRNA amidotransferase subunit B-like [IPR003789]", "Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C-terminal, domain 2 [IPR023168]", "At2g17340, three-helix bundle domain [IPR035073]", "Atg6/Beclin C-terminal domain superfamily [IPR038274]", "Autophagy protein Atg5, UblA domain [IPR042527]", "Autophagy protein Atg5, helix rich domain [IPR042526]", "B30.2/SPRY domain superfamily [IPR043136]", "BAG domain superfamily [IPR036533]", "BEACH domain superfamily [IPR036372]", "BRCT domain superfamily [IPR036420]", "BRK domain superfamily [IPR037259]", "BRO1 domain superfamily [IPR038499]", "BSD domain superfamily [IPR035925]", "Band 7/SPFH domain superfamily [IPR036013]", "Barrier-to-autointegration factor, BAF superfamily [IPR036617]", "Bcl-2-like superfamily [IPR036834]", "Bcr-Abl oncoprotein oligomerisation domain superfamily [IPR036481]", "Beta-Galactosidase/glucuronidase domain superfamily [IPR036156]", "Beta-catenin-interacting ICAT superfamily [IPR036911]", "Beta-grasp domain superfamily [IPR012675]", "Beta-hexosaminidase-like, domain 2 [IPR029018]", "Beta-lactamase/transpeptidase-like [IPR012338]", "BolA-like superfamily [IPR036065]", "Branched-chain-amino-acid aminotransferase-like, C-terminal [IPR043132]", "Branched-chain-amino-acid aminotransferase-like, N-terminal [IPR043131]", "Bromo adjacent homology (BAH) domain superfamily [IPR043151]", "Bromodomain-like superfamily [IPR036427]", "C-type lectin fold [IPR016187]", "C-type lectin-like/link domain superfamily [IPR016186]", "C2 domain superfamily [IPR035892]", "CAP Gly-rich domain superfamily [IPR036859]", "CCR4-NOT complex subunit 2/3/5, N-terminal domain superfamily [IPR038635]", "CCR4-NOT subunit 1, TTP binding domain superfamily [IPR038535]", "CDC48 domain 2-like superfamily [IPR029067]", "CDP-alcohol phosphatidyltransferase, transmembrane domain [IPR043130]", "CENP-B, dimerisation domain superfamily [IPR034882]", "CGI121/TPRKB superfamily [IPR036504]", "CH domain superfamily [IPR036872]", "CKK domain superfamily [IPR038209]", "CPI-17 superfamily [IPR036658]", "CRAL-TRIO lipid binding domain superfamily [IPR036865]", "CRAL/TRIO, N-terminal domain superfamily [IPR036273]", "CRIB domain superfamily [IPR036936]", "CSTF1, dimerization domain superfamily [IPR038184]", "Cadherin-like superfamily [IPR015919]", "Calcyclin-binding protein, N-terminal [IPR037201]", "Calpain large subunit, domain III superfamily [IPR036213]", "Calreticulin/calnexin, P domain superfamily [IPR009033]", "Carbamoyl-phosphate synthase small subunit, N-terminal domain superfamily [IPR036480]", "Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily [IPR036897]", "Carbohydrate-binding-like fold [IPR013784]", "Carbon-nitrogen hydrolase superfamily [IPR036526]", "Carboxypeptidase-like, regulatory domain superfamily [IPR008969]", "Carnitine o-acyltransferase, N-terminal [IPR042572]", "Casein kinase II subunit beta-like [IPR035991]", "Casein kinase II, regulatory subunit, N-terminal [IPR016149]", "Catenin binding domain superfamily [IPR027397]", "Cathepsin C, exclusion domain superfamily [IPR036496]", "Cation efflux transmembrane domain superfamily [IPR027469]", "Cdc37, Hsp90-binding domain superfamily [IPR038189]", "Cell division control protein 73, C-terminal domain superfamily [IPR038103]", "Chaperone J-domain superfamily [IPR036869]", "Chitinase insertion domain superfamily [IPR029070]", "Chloramphenicol acetyltransferase-like domain superfamily [IPR023213]", "Chloride channel, core [IPR014743]", "Choline/Carnitine o-acyltransferase, domain 2 [IPR042231]", "Chondroitin AC/alginate lyase [IPR008929]", "Chromo-like domain superfamily [IPR016197]", "Citrate synthase superfamily [IPR036969]", "Citrate synthase-like, large alpha subdomain [IPR016142]", "Citrate synthase-like, small alpha subdomain [IPR016143]", "Class I and II aminoacyl-tRNA synthetase, tRNA-binding arm [IPR010978]", "Class I glutamine amidotransferase-like [IPR029062]", "Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) [IPR045864]", "Class II aldolase/adducin N-terminal domain superfamily [IPR036409]", "Clathrin adaptor, appendage, Ig-like subdomain superfamily [IPR013041]", "Clathrin adaptor, beta-adaptin, appendage, Ig-like subdomain [IPR013037]", "Clathrin heavy chain, N-terminal [IPR016025]", "ClpP/crotonase-like domain superfamily [IPR029045]", "Coatomer, gamma subunit, appendage domain superfamily [IPR037067]", "Coatomer/calthrin adaptor appendage, C-terminal subdomain [IPR009028]", "Cobalamin (vitamin B12)-dependent enzyme, catalytic [IPR016176]", "Cobalamin adenosyltransferase-like superfamily [IPR036451]", "Cobalamin-binding domain superfamily [IPR036724]", "Concanavalin A-like lectin/glucanase domain superfamily [IPR013320]", "Creatinase/Aminopeptidase P/Spt16, N-terminal [IPR029149]", "Creatinase/aminopeptidase-like [IPR036005]", "Cullin homology domain superfamily [IPR036317]", "Cullin repeat-like-containing domain superfamily [IPR016159]", "Cupredoxin [IPR008972]", "Cyclase-associated protein CAP/septum formation inhibitor MinC, C-terminal [IPR016098]", "Cyclic nucleotide-binding-like [IPR018490]", "Cyclic phosphodiesterase [IPR009097]", "Cyclin-like superfamily [IPR036915]", "Cyclophilin-like domain superfamily [IPR029000]", "Cytidine deaminase-like [IPR016193]", "Cytochrome C oxidase subunit II, transmembrane domain superfamily [IPR036257]", "Cytochrome P450 superfamily [IPR036396]", "Cytochrome b-c1 complex subunit 7 superfamily [IPR036544]", "Cytochrome b-c1 complex subunit 8 superfamily [IPR036642]", "Cytochrome b-c1 complex subunit 9 superfamily [IPR036656]", "Cytochrome b5-like heme/steroid binding domain superfamily [IPR036400]", "Cytochrome bc1 complex subunit Rieske, transmembrane domain superfamily [IPR037008]", "Cytochrome c oxidase subunit IV superfamily [IPR036639]", "Cytochrome c oxidase subunit VIIc superfamily [IPR036636]", "Cytochrome c oxidase, subunit VIIa superfamily [IPR036539]", "Cytochrome c oxidase, subunit Va/VI superfamily [IPR036545]", "Cytochrome c oxidase, subunit Vb superfamily [IPR036972]", "Cytochrome c oxidase-like, subunit I superfamily [IPR036927]", "Cytochrome c-like domain superfamily [IPR036909]", "Cytochrome c1, transmembrane anchor, C-terminal [IPR021157]", "Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily [IPR011048]", "DCN1-like, PONY binding domain [IPR042460]", "DENN domain, C-terminal lobe [IPR043153]", "DHS-like NAD/FAD-binding domain superfamily [IPR029035]", "DIX domain superfamily [IPR038207]", "DNA breaking-rejoining enzyme, catalytic core [IPR011010]", "DNA fragmentation factor 45kDa, C-terminal [IPR027296]", "DNA glycosylase [IPR011257]", "DNA ligase, ATP-dependent, N-terminal domain superfamily [IPR036599]", "DNA mismatch repair protein MutS, N-terminal [IPR016151]", "DNA mismatch repair protein MutS, core domain superfamily [IPR036187]", "DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal [IPR008921]", "DNA polymerase alpha, subunit B, N-terminal domain superfamily [IPR043034]", "DNA polymerase alpha, zinc finger domain superfamily [IPR038256]", "DNA polymerase family B, thumb domain [IPR042087]", "DNA polymerase, palm domain superfamily [IPR023211]", "DNA repair protein XRCC4-like, C-terminal [IPR014751]", "DNA topoisomerase I, DNA binding, N-terminal domain 1 [IPR013034]", "DNA topoisomerase I, DNA binding, N-terminal domain 2 [IPR013030]", "DNA topoisomerase I, DNA binding, eukaryotic-type, N-terminal domain superfamily [IPR036202]", "DNA topoisomerase I, catalytic core, alpha-helical subdomain, eukaryotic-type [IPR014711]", "DNA topoisomerase I, catalytic core, alpha/beta subdomain [IPR014727]", "DNA topoisomerase, type IIA, alpha-helical domain superfamily [IPR013757]", "DNA topoisomerase, type IIA, domain A, alpha-beta [IPR013758]", "DNA topoisomerase, type IIA, subunit B, C-terminal [IPR013759]", "DNA topoisomerase, type IIA-like domain superfamily [IPR013760]", "DNA-binding domain superfamily [IPR016177]", "DNA-directed RNA polymerase, N-terminal domain superfamily [IPR037159]", "DNA-directed RNA polymerase, insert domain superfamily [IPR036643]", "DNA-directed RNA polymerase, subunit 2, hybrid-binding domain superfamily [IPR037033]", "DNA/RNA non-specific endonuclease superfamily [IPR044929]", "DNA/RNA polymerase superfamily [IPR043502]", "DNA/RNA-binding protein KIN17, WH-like domain superfamily [IPR038254]", "DUSP-like superfamily [IPR035927]", "Daxx, N-terminal domain superfamily [IPR038298]", "Dbl homology (DH) domain superfamily [IPR035899]", "Death-like domain superfamily [IPR011029]", "Dedicator of cytokinesis, C-terminal, lobe A [IPR043161]", "Dedicator of cytokinesis, C-terminal, lobe C [IPR043162]", "Dedicator of cytokinesis, N-terminal, subdomain 1 [IPR042455]", "Deoxyhypusine synthase superfamily [IPR036982]", "DhaL domain superfamily [IPR036117]", "Diaphanous, GTPase-binding domain superfamily [IPR044933]", "Dicer dimerisation domain superfamily [IPR038248]", "Dihydrofolate reductase-like domain superfamily [IPR024072]", "Dihydropteroate synthase-like [IPR011005]", "Dimeric alpha-beta barrel [IPR011008]", "Diphthamide synthesis DPH1/DPH2, domain 1 [IPR042263]", "Diphthamide synthesis DPH1/DPH2, domain 2 [IPR042264]", "Diphthamide synthesis DPH1/DPH2, domain 3 [IPR042265]", "Disintegrin domain superfamily [IPR036436]", "Dynein heavy chain AAA lid domain superfamily [IPR042219]", "Dynein heavy chain, AAA1 domain, small subdomain [IPR043157]", "Dynein heavy chain, C-terminal domain, barrel region [IPR043160]", "Dynein heavy chain, domain 2, N-terminal [IPR042222]", "Dynein heavy chain, linker, subdomain 3 [IPR042228]", "Dynein light chain superfamily [IPR037177]", "E2 domain superfamily [IPR036176]", "E3-binding domain superfamily [IPR036625]", "EB1, C-terminal domain superfamily [IPR036133]", "EF-G domain III/V-like [IPR035647]", "EF-hand domain pair [IPR011992]", "ENTH/VHS [IPR008942]", "ERO1-like superfamily [IPR037192]", "ERV/ALR sulfhydryl oxidase domain superfamily [IPR036774]", "ESCRT assembly domain [IPR037202]", "ESCRT-II complex, Vps25 subunit, N-terminal winged helix [IPR014041]", "EXOC6/PINT-1/Sec15/Tip20, C-terminal, domain 2 [IPR042044]", "Elongation factor EF1B gamma, C-terminal domain superfamily [IPR036433]", "Elongation factor Ts, dimerisation domain superfamily [IPR036402]", "Endonuclease/exonuclease/phosphatase superfamily [IPR036691]", "Endoplasmic reticulum resident protein 29, C-terminal domain superfamily [IPR036356]", "Enhancer of mRNA-decapping protein 4, conserved C-terminal domain [IPR044938]", "Enhancer of rudimentary superfamily [IPR035912]", "Enolase-like, C-terminal domain superfamily [IPR036849]", "Enolase-like, N-terminal [IPR029017]", "Enoyl-CoA hydratase, C-terminal [IPR014748]", "Eukaryotic translation initiation factor 3-like domain superfamily [IPR023194]", "Exocyst complex component EXOC3/Sec6, C-terminal domain [IPR042532]", "Exocyst complex component EXOC6/Sec15, C-terminal, domain 1 [IPR042045]", "Exocyst component Exo84, C-terminal, subdomain 1 [IPR042561]", "Exocyst component Exo84, C-terminal, subdomain 2 [IPR042560]", "Exoribonuclease, PH domain 2 superfamily [IPR036345]", "F-actin capping protein, alpha subunit, domain 1 [IPR042489]", "F-actin-capping protein subunit alpha/beta [IPR037282]", "F-actin-capping protein subunit alpha/beta, domain 2 [IPR042276]", "F-actin-capping protein subunit beta, N-terminal domain [IPR043175]", "F-box-like domain superfamily [IPR036047]", "F1F0 ATP synthase OSCP/delta subunit, N-terminal domain superfamily [IPR026015]", "FAD-binding, type PCMH, subdomain 1 [IPR016167]", "FAD-binding, type PCMH, subdomain 2 [IPR016169]", "FAD-binding, type PCMH-like superfamily [IPR036318]", "FAD-linked oxidase-like, C-terminal [IPR016164]", "FAD/NAD(P)-binding domain superfamily [IPR036188]", "FAD/NAD-linked reductase, dimerisation domain superfamily [IPR016156]", "FERM superfamily, second domain [IPR035963]", "FERM/acyl-CoA-binding protein superfamily [IPR014352]", "FF domain superfamily [IPR036517]", "FIP-RBD, C-terminal domain superfamily [IPR037245]", "FKBP12-rapamycin binding domain superfamily [IPR036738]", "FMN-binding split barrel [IPR012349]", "FTO, C-terminal domain superfamily [IPR038413]", "Fe-S cluster assembly domain superfamily [IPR034904]", "Ferredoxin-NADP reductase (FNR), nucleotide-binding domain [IPR039261]", "Ferritin-like superfamily [IPR009078]", "Fibronectin type II domain superfamily [IPR036943]", "Fibronectin type III superfamily [IPR036116]", "Flavoprotein-like superfamily [IPR029039]", "Formin, FH2 domain superfamily [IPR042201]", "Formyl transferase, N-terminal domain superfamily [IPR036477]", "Formyl transferase-like, C-terminal domain superfamily [IPR011034]", "Fumarase/histidase, N-terminal [IPR024083]", "Fumarate reductase/succinate dehydrogenase flavoprotein-like, C-terminal domain superfamily [IPR037099]", "Fumarylacetoacetase, N-terminal domain superfamily [IPR036462]", "Fumarylacetoacetase-like, C-terminal domain superfamily [IPR036663]", "G protein alpha subunit, helical insertion [IPR011025]", "G-protein gamma-like domain superfamily [IPR036284]", "GAD-like domain superfamily [IPR004115]", "GAR domain superfamily [IPR036534]", "GAT domain superfamily [IPR038425]", "GHMP kinase, C-terminal domain superfamily [IPR036554]", "GINS complex, subunit Psf3 superfamily [IPR038437]", "GINS, helical bundle-like domain superfamily [IPR036224]", "GM2-AP, lipid-recognition domain superfamily [IPR036846]", "GMP phosphodiesterase, delta subunit superfamily [IPR037036]", "GOLD domain superfamily [IPR036598]", "GSKIP domain superfamily [IPR023231]", "GTF2I-like repeat superfamily [IPR036647]", "GTP cyclohydrolase 1 type 2/Nif3 superfamily [IPR036069]", "GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1 [IPR027266]", "GTP-binding protein, orthogonal bundle domain superfamily [IPR023179]", "GTP1/OBG domain superfamily [IPR036726]", "GYF-like domain superfamily [IPR035445]", "Galactose mutarotase-like domain superfamily [IPR011013]", "Galactose oxidase/kelch, beta-propeller [IPR011043]", "Galactose-binding-like domain superfamily [IPR008979]", "Gamma-glutamyl cyclotransferase-like superfamily [IPR036568]", "Gamma-tubulin complex component, C-terminal domain superfamily [IPR042241]", "Gelsolin-like domain superfamily [IPR036180]", "Globular protein, non-globular alpha/beta subunit [IPR011070]", "Glutamine synthetase/guanido kinase, catalytic domain [IPR014746]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 1 [IPR042558]", "Glutaminyl-tRNA synthetase, class Ib, non-specific RNA-binding domain, N-terminal, subdomain 2 [IPR042559]", "Glutathione S-transferase, C-terminal domain superfamily [IPR036282]", "Glutathione synthase, C-terminal, eukaryotic [IPR014709]", "Glutathione synthase, N-terminal, eukaryotic [IPR014049]", "Glutathione synthase, alpha-helical [IPR014042]", "Glutathione synthase, substrate-binding domain superfamily [IPR037013]", "Glycine cleavage T-protein/YgfZ, C-terminal [IPR029043]", "Glycolipid transfer protein superfamily [IPR036497]", "Glycoside hydrolase 38, N-terminal domain superfamily [IPR027291]", "Glycoside hydrolase families 57/38, central domain superfamily [IPR028995]", "Glycoside hydrolase family 38, central domain superfamily [IPR037094]", "Glycoside hydrolase superfamily [IPR017853]", "Glycoside hydrolase-type carbohydrate-binding [IPR014718]", "Glycoside hydrolase/deacetylase, beta/alpha-barrel [IPR011330]", "Glycosyl hydrolase family 63, N-terminal domain superfamily [IPR038518]", "Glycosyl hydrolase, all-beta [IPR013780]", "Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase [IPR029068]", "Golgi phosphoprotein 3-like domain superfamily [IPR038261]", "GroEL-like apical domain superfamily [IPR027409]", "GroEL-like equatorial domain superfamily [IPR027413]", "GroES chaperonin superfamily [IPR037124]", "GroES-like superfamily [IPR011032]", "Growth arrest and DNA damage-inducible proteins-interacting protein 1 domain superfamily [IPR043035]", "Growth factor receptor cysteine-rich domain superfamily [IPR009030]", "GrpE nucleotide exchange factor, coiled-coil [IPR013805]", "GrpE nucleotide exchange factor, head [IPR009012]", "Guanylate-binding protein, C-terminal domain superfamily [IPR036543]", "H/ACA RNP complex subunit Gar1/Naf1, Cbf5-binding domain [IPR038664]", "H/ACA ribonucleoprotein complex, subunit Nop10 superfamily [IPR036756]", "HAD superfamily [IPR023214]", "HAD-like superfamily [IPR036412]", "HAD-superfamily hydrolase, subfamily IA, REG-2-like, capping domain superfamily [IPR044924]", "HBS1-like protein, N-terminal domain superfamily [IPR037189]", "HECT, E3 ligase catalytic domain [IPR035983]", "HIT-like superfamily [IPR036265]", "HIV integrase-binding domain superfamily [IPR036218]", "HORMA domain superfamily [IPR036570]", "HR1 repeat superfamily [IPR036274]", "HRDC domain superfamily [IPR044876]", "HRDC-like superfamily [IPR010997]", "HSP20-like chaperone [IPR008978]", "HSP40/DnaJ peptide-binding [IPR008971]", "HSP90, C-terminal domain [IPR037196]", "Haem oxygenase-like, multi-helical [IPR016084]", "Heat shock protein 70kD, C-terminal domain superfamily [IPR029048]", "Heat shock protein 70kD, peptide-binding domain superfamily [IPR029047]", "Heat shock protein DnaJ, cysteine-rich domain superfamily [IPR036410]", "Helix hairpin bin domain superfamily [IPR029012]", "Helix-hairpin-helix, base-excision DNA repair, C-terminal [IPR023170]", "Helix-loop-helix DNA-binding domain superfamily [IPR036638]", "Hemimethylated DNA-binding domain superfamily [IPR036623]", "High mobility group box domain superfamily [IPR036910]", "His-Me finger superfamily [IPR044925]", "Histidine kinase/HSP90-like ATPase superfamily [IPR036890]", "Histidine phosphatase superfamily [IPR029033]", "Histone acetyl transferase 1, N-terminal domain superfamily [IPR037113]", "Histone acetyltransferase HAT1, C-terminal [IPR013523]", "Histone deacetylase domain superfamily [IPR037138]", "Histone-fold [IPR009072]", "Homeobox-like domain superfamily [IPR009057]", "Homocysteine-binding domain superfamily [IPR036589]", "HotDog domain superfamily [IPR029069]", "Hydroxymethylglutaryl-CoA reductase, N-terminal [IPR023282]", "Hydroxymethylglutaryl-CoA reductase, class I/II, NAD/NADP-binding domain superfamily [IPR009023]", "Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic domain superfamily [IPR023074]", "Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding domain superfamily [IPR009029]", "Hypoxia-inducible factor 1-alpha inhibitor, domain II [IPR027452]", "I/LWEQ domain superfamily [IPR035964]", "ISWI, HAND domain superfamily [IPR036306]", "Immunoglobulin E-set [IPR014756]", "Immunoglobulin-like domain superfamily [IPR036179]", "Immunoglobulin-like fold [IPR013783]", "Impact, N-terminal domain superfamily [IPR036956]", "Importin-alpha, importin-beta-binding domain superfamily [IPR036975]", "Initiation factor 2B-like, C-terminal [IPR042529]", "Inorganic polyphosphate/ATP-NAD kinase, N-terminal [IPR017438]", "Inorganic pyrophosphatase superfamily [IPR036649]", "Inosine triphosphate pyrophosphatase-like [IPR029001]", "Integrin alpha, N-terminal [IPR028994]", "Integrin beta tail domain superfamily [IPR036349]", "Integrin domain superfamily [IPR032695]", "Interferon regulatory factor 2-binding protein 1/2, C3HC4-type RING finger superfamily [IPR044882]", "Invasin/intimin cell-adhesion fragments [IPR008964]", "Isochorismatase-like superfamily [IPR036380]", "Isopenicillin N synthase-like superfamily [IPR027443]", "Isoprenoid synthase domain superfamily [IPR008949]", "K Homology domain, type 1 superfamily [IPR036612]", "K homology domain superfamily, prokaryotic type [IPR009019]", "K homology domain-like, alpha/beta [IPR015946]", "KA1 domain/Ssp2, C-terminal [IPR028375]", "Kelch-type beta propeller [IPR015915]", "Kinesin motor domain superfamily [IPR036961]", "Kinesin-like protein Kif23, Arf6-interacting domain superfamily [IPR038105]", "Kringle-like fold [IPR013806]", "Ku, C-terminal domain superfamily [IPR036494]", "Ku70, bridge and pillars domain superfamily [IPR027388]", "L-Aspartase-like [IPR008948]", "L1 transposable element, C-terminal domain [IPR042566]", "L21-like superfamily [IPR036164]", "L27 domain superfamily [IPR036892]", "L28p-like [IPR034704]", "LAP1C-like, C-terminal domain superfamily [IPR038599]", "LDL receptor-like superfamily [IPR036055]", "LEM/LEM-like domain superfamily [IPR011015]", "LIS1, N-terminal [IPR037190]", "LSM domain superfamily [IPR010920]", "Lactate dehydrogenase/glycoside hydrolase, family 4, C-terminal [IPR015955]", "Lambda repressor-like, DNA-binding domain superfamily [IPR010982]", "Lamin tail domain superfamily [IPR036415]", "LepA, C-terminal domain superfamily [IPR038363]", "Leucine-rich repeat domain superfamily [IPR032675]", "LexA/Signal peptidase-like superfamily [IPR036286]", "Longin-like domain superfamily [IPR011012]", "LysM domain superfamily [IPR036779]", "MAGE homology domain, winged helix WH1 motif [IPR041898]", "MAGE homology domain, winged helix WH2 motif [IPR041899]", "MAN1, winged-helix domain [IPR041885]", "MFS transporter superfamily [IPR036259]", "MHC class I-like antigen recognition-like superfamily [IPR037055]", "MHC classes I/II-like antigen recognition protein [IPR011162]", "MIT domain superfamily [IPR036181]", "MOB kinase activator superfamily [IPR036703]", "MRG, C-terminal domain superfamily [IPR038217]", "MRP-L47 superfamily, mitochondrial [IPR038340]", "MTERF superfamily, mitochondrial/chloroplastic [IPR038538]", "MTH938-like superfamily [IPR036748]", "Macro domain-like [IPR043472]", "Malic enzyme, N-terminal domain superfamily [IPR037062]", "Malonyl-CoA ACP transacylase, ACP-binding [IPR016036]", "Manganese/iron superoxide dismutase, C-terminal domain superfamily [IPR036314]", "Manganese/iron superoxide dismutase, N-terminal domain superfamily [IPR036324]", "Mannose-6-phosphate receptor binding domain superfamily [IPR009011]", "Mediator complex subunit 25, PTOV domain superfamily [IPR038196]", "Mediator complex, subunit Med7/Med21-like [IPR037212]", "Membrane associated eicosanoid/glutathione metabolism-like domain superfamily [IPR023352]", "Metal-dependent hydrolase [IPR032466]", "Metal-dependent hydrolase, composite domain superfamily [IPR011059]", "Metallo-dependent phosphatase-like [IPR029052]", "Metalloenzyme, LuxS/M16 peptidase-like [IPR011249]", "Metallopeptidase, catalytic domain superfamily [IPR024079]", "Methionine synthase domain [IPR036594]", "Methionyl-tRNA synthetase, Zn-domain [IPR029038]", "Methylglyoxal synthase-like domain superfamily [IPR036914]", "Methylpurine-DNA glycosylase superfamily [IPR036995]", "Methylthioribose-1-phosphate isomerase, N-terminal [IPR027363]", "Methylthiotransferase, N-terminal domain superfamily [IPR038135]", "Mib/herc2 domain superfamily [IPR037252]", "MitoNEET, CDGSH iron-sulfur domain [IPR042216]", "Mitochondrial carrier domain superfamily [IPR023395]", "Mitochondrial cytochrome c oxidase subunit VIc/VIIs superfamily [IPR037169]", "Mitochondrial glycoprotein superfamily [IPR036561]", "Mitochondrial outer membrane translocase complex, Tom20 domain superfamily [IPR023392]", "MoaB/Mog-like domain superfamily [IPR036425]", "MoeA, C-terminal, domain IV superfamily [IPR036688]", "MoeA, N-terminal and linker domain superfamily [IPR036135]", "Moesin tail domain superfamily [IPR008954]", "Molybdopterin cofactor biosynthesis C (MoaC) domain superfamily [IPR036522]", "Mre11, capping domain [IPR038487]", "Mss4-like superfamily [IPR011057]", "Mss4/translationally controlled tumour-associated TCTP [IPR011323]", "Multifunctional 2-oxoglutarate metabolism enzyme, C-terminal domain superfamily [IPR042179]", "MutS, connector domain superfamily [IPR036678]", "Myosin S1 fragment, N-terminal [IPR008989]", "NAC A/B domain superfamily [IPR038187]", "NAD kinase/diacylglycerol kinase-like domain superfamily [IPR016064]", "NAD(P)-binding domain superfamily [IPR036291]", "NADH-quinone oxidoreductase subunit E, N-terminal [IPR041921]", "NADH-ubiquinone oxidoreductase 51kDa subunit, FMN-binding domain superfamily [IPR037225]", "NADH-ubiquinone oxidoreductase 51kDa subunit, iron-sulphur binding domain superfamily [IPR037207]", "NADH:ubiquinone oxidoreductase, 30kDa subunit superfamily [IPR037232]", "NADP-dependent oxidoreductase domain superfamily [IPR036812]", "NADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamily [IPR023173]", "NAP-like superfamily [IPR037231]", "NET domain superfamily [IPR038336]", "NO signalling/Golgi transport ligand-binding domain superfamily [IPR024096]", "NOB1 zinc finger-like superfamily [IPR036283]", "NSFL1 cofactor p47, SEP domain superfamily [IPR036241]", "NTF2-like domain superfamily [IPR032710]", "NUDIX hydrolase-like domain superfamily [IPR015797]", "NVL2, N-terminal domain superfamily [IPR038100]", "NagB/RpiA transferase-like [IPR037171]", "Neurolysin/Thimet oligopeptidase, N-terminal [IPR024080]", "Neurolysin/Thimet oligopeptidase, domain 2 [IPR024077]", "Nibrin, second BRCT domain superfamily [IPR043014]", "Nicotinate phosphoribosyltransferase-like, C-terminal [IPR036068]", "Nitrogen regulatory PII-like, alpha/beta [IPR011322]", "Nitrogen regulatory protein PII/ATP phosphoribosyltransferase, C-terminal [IPR015867]", "Nitrous oxide reductase, N-terminal [IPR011045]", "Nop domain superfamily [IPR036070]", "Nop, C-terminal domain [IPR042239]", "Notch-like domain superfamily [IPR035993]", "Nucleic acid-binding, OB-fold [IPR012340]", "Nucleophile aminohydrolases, N-terminal [IPR029055]", "Nucleoplasmin core domain superfamily [IPR036824]", "Nucleoporin, Nup155-like, C-terminal, subdomain 1 [IPR042533]", "Nucleoporin, Nup155-like, C-terminal, subdomain 2 [IPR042537]", "Nucleoporin, Nup155-like, C-terminal, subdomain 3 [IPR042538]", "Nucleoside diphosphate kinase-like domain superfamily [IPR036850]", "Nucleoside phosphorylase superfamily [IPR035994]", "Nucleotide-binding alpha-beta plait domain superfamily [IPR012677]", "Nucleotide-diphospho-sugar transferases [IPR029044]", "Nucleotidyltransferase superfamily [IPR043519]", "Nucleotidyltransferase, class I-like, C-terminal [IPR011068]", "NusG, N-terminal domain superfamily [IPR036735]", "Oxygen-dependent coproporphyrinogen III oxidase superfamily [IPR036406]", "Oxysterol-binding protein superfamily [IPR037239]", "P-loop containing nucleoside triphosphate hydrolase [IPR027417]", "P-type ATPase, A domain superfamily [IPR008250]", "P-type ATPase, cytoplasmic domain N [IPR023299]", "P-type ATPase, transmembrane domain superfamily [IPR023298]", "P-type trefoil domain superfamily [IPR044913]", "PABC (PABP) domain [IPR036053]", "PADR1 domain superfamily [IPR038650]", "PAZ domain superfamily [IPR036085]", "PBDC1-like domain superfamily [IPR023139]", "PDCD5-like superfamily [IPR036883]", "PDZ superfamily [IPR036034]", "PEBP-like superfamily [IPR036610]", "PFU domain superfamily [IPR038122]", "PH-like domain superfamily [IPR011993]", "PHR domain superfamily [IPR038648]", "PIN-like domain superfamily [IPR029060]", "PINIT domain superfamily [IPR038654]", "PITH domain superfamily [IPR037047]", "PKD domain superfamily [IPR035986]", "PLC-like phosphodiesterase, TIM beta/alpha-barrel domain superfamily [IPR017946]", "PLP-binding barrel [IPR029066]", "PNPase/RNase PH domain superfamily [IPR027408]", "POLO box domain superfamily [IPR036947]", "PPM-type phosphatase domain superfamily [IPR036457]", "PRC-barrel-like superfamily [IPR011033]", "PRP4-like superfamily [IPR036285]", "PTPA superfamily [IPR037218]", "PUA domain superfamily [IPR036974]", "PUA-like superfamily [IPR015947]", "PUB-like domain superfamily [IPR036339]", "PWI domain superfamily [IPR036483]", "PX domain superfamily [IPR036871]", "Paired amphipathic helix superfamily [IPR036600]", "Pancreatic trypsin inhibitor Kunitz domain superfamily [IPR036880]", "PapD-like superfamily [IPR008962]", "Papain-like cysteine peptidase superfamily [IPR038765]", "Pectin lyase fold [IPR012334]", "Pectin lyase fold/virulence factor [IPR011050]", "Pelota/DOM34, N-terminal domain [IPR038069]", "Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily [IPR036959]", "Peptidase C65, otubain, subdomain 2 [IPR042467]", "Peptidase C65, otubain, subdomain 1 [IPR042468]", "Peptidase M1, LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily [IPR038502]", "Peptidase M13, domain 2 [IPR042089]", "Peptidase M4/M1, CTD superfamily [IPR027268]", "Peptidase M41-like [IPR037219]", "Peptidase M60, enhancin-like domain 3 [IPR042279]", "Peptidase S1, PA clan [IPR009003]", "Peptidase S59, nucleoporin superfamily [IPR036903]", "Peptidase S8/S53 domain superfamily [IPR036852]", "Peptidyl-tRNA hydrolase II domain superfamily [IPR023476]", "Pex19, C-terminal domain superfamily [IPR038322]", "Phenylalanyl-tRNA synthetase-like, B3/B4 [IPR020825]", "Phosphatidic acid phosphatase type 2/haloperoxidase superfamily [IPR036938]", "Phosphatidylinositol 3-/4-kinase, catalytic domain superfamily [IPR036940]", "Phosphatidylinositol-4-phosphate 5-kinase, N-terminal [IPR027484]", "Phosphoenolpyruvate carboxykinase, C-terminal [IPR013035]", "Phosphoenolpyruvate carboxykinase, N-terminal [IPR008210]", "Phosphofructokinase superfamily [IPR035966]", "Phosphoglucose isomerase, C-terminal [IPR023096]", "Phosphoglycerate kinase superfamily [IPR036043]", "Phosphoglycerate kinase, N-terminal [IPR015824]", "Phosphoglycolate phosphatase-like, domain 2 [IPR023198]", "Phosphoinositide 3-kinase, accessory (PIK) domain superfamily [IPR042236]", "Phospholipase B-like, domain 1 [IPR043040]", "Phospholipase B-like, domain 2 [IPR043041]", "Phospholipase B-like, domain 3 [IPR043042]", "Phosphoribosylformylglycinamidine synthase subunit PurS-like superfamily [IPR036604]", "Phosphoribosylglycinamide synthetase, C-domain superfamily [IPR037123]", "Phosphoribosyltransferase-like [IPR029057]", "Phosphorylated adapter RNA export protein, RNA-binding domain superfamily [IPR038092]", "Phosphotransferase/anion transporter [IPR016152]", "Phosphotyrosine protein phosphatase I superfamily [IPR036196]", "Phosphotyrosyl phosphatase activator, C-terminal lid domain [IPR043170]", "Plakin repeat superfamily [IPR035915]", "Plus3-like superfamily [IPR036128]", "Poly(ADP-ribose) polymerase, regulatory domain superfamily [IPR036616]", "Polyketide synthase, dehydratase domain superfamily [IPR042104]", "Polymerase/histidinol phosphatase-like [IPR016195]", "Polyribonucleotide nucleotidyltransferase, RNA-binding domain superfamily [IPR036456]", "Porin domain superfamily [IPR023614]", "Porphobilinogen deaminase, C-terminal domain superfamily [IPR036803]", "Pre-ATP-grasp domain superfamily [IPR016185]", "Pre-mRNA-processing-splicing factor 8, U5-snRNA-binding domain superfamily [IPR042516]", "Pre-mRNA-splicing factor Isy1 superfamily [IPR037200]", "Prefoldin [IPR009053]", "Profilin superfamily [IPR036140]", "Prolyl-tRNA synthetase, class II [IPR017449]", "Proteasomal ubiquitin receptor Rpn13/ADRM1, Pru domain superfamily [IPR038633]", "Proteasome activator PA28, C-terminal domain superfamily [IPR036997]", "Proteasome activator PA28, N-terminal domain superfamily [IPR036996]", "Proteasome activator superfamily [IPR036252]", "Proteasome assembly chaperone 2 superfamily [IPR038389]", "Protein arginine methyltransferase NDUFAF7 superfamily [IPR038375]", "Protein kinase-like domain superfamily [IPR011009]", "Protein translocase SecE domain superfamily [IPR023391]", "Protein-tyrosine phosphatase-like [IPR029021]", "Prp8 RNase domain IV, fingers region [IPR043173]", "Prp8 RNase domain IV, palm region [IPR043172]", "Pseudouridine synthase I, TruA, C-terminal [IPR020095]", "Pseudouridine synthase TruA/RsuA/RluB/E/F, N-terminal [IPR020094]", "Pseudouridine synthase, TruD, catalytic domain [IPR042214]", "Pseudouridine synthase, catalytic domain superfamily [IPR020103]", "Pterin 4 alpha carbinolamine dehydratase superfamily [IPR036428]", "PurM-like, C-terminal domain superfamily [IPR036676]", "PurM-like, N-terminal domain superfamily [IPR036921]", "Putative DNA-binding domain superfamily [IPR009061]", "Putative deacetylase LmbE-like domain superfamily [IPR024078]", "Pyridoxal phosphate-dependent transferase [IPR015424]", "Pyridoxal phosphate-dependent transferase, major domain [IPR015421]", "Pyridoxal phosphate-dependent transferase, small domain [IPR015422]", "Pyruvate kinase, C-terminal domain superfamily [IPR036918]", "Pyruvate kinase, insert domain superfamily [IPR015806]", "Pyruvate kinase-like domain superfamily [IPR040442]", "Pyruvate kinase-like, insert domain superfamily [IPR011037]", "Pyruvate/Phosphoenolpyruvate kinase-like domain superfamily [IPR015813]", "Queuine tRNA-ribosyltransferase-like [IPR036511]", "Quinoprotein alcohol dehydrogenase-like superfamily [IPR011047]", "Quinoprotein amine dehydrogenase, beta chain-like [IPR011044]", "R3H domain superfamily [IPR036867]", "RAP domain superfamily [IPR036744]", "RGS domain superfamily [IPR036305]", "RGS, subdomain 2 [IPR044926]", "RNA 3'-terminal phosphate cyclase domain superfamily [IPR037136]", "RNA 3'-terminal phosphate cyclase, insert domain superfamily [IPR036553]", "RNA 3'-terminal phosphate cyclase/enolpyruvate transferase, alpha/beta [IPR013792]", "RNA polymerase Rpb1, clamp domain superfamily [IPR044893]", "RNA polymerase Rpb1, domain 3 superfamily [IPR042102]", "RNA polymerase Rpb1, domain 7 superfamily [IPR038593]", "RNA polymerase Rpb1, funnel domain superfamily [IPR038120]", "RNA polymerase Rpb2, OB-fold [IPR014724]", "RNA polymerase Rpb2, domain 2 superfamily [IPR037034]", "RNA polymerase Rpb5, N-terminal domain superfamily [IPR036710]", "RNA polymerase Rpb7-like, N-terminal domain superfamily [IPR036898]", "RNA polymerase subunit RPB10 [IPR023580]", "RNA polymerase, RBP11-like subunit [IPR036603]", "RNA-binding S4 domain superfamily [IPR036986]", "RNA-binding domain superfamily [IPR035979]", "RNase P subunit Pop5/Rpp14/Rnp2-like domain superfamily [IPR038085]", "RPB5-like RNA polymerase subunit superfamily [IPR035913]", "RPN13, DEUBAD domain superfamily [IPR038108]", "RRF superfamily [IPR036191]", "Rab geranylgeranyltransferase, alpha subunit, insert-domain superfamily [IPR036254]", "Rab-GTPase-TBC domain superfamily [IPR035969]", "Radical SAM, alpha/beta horseshoe [IPR023404]", "Ran-GTPase activating protein 1, C-terminal domain superfamily [IPR036720]", "Ras guanine nucleotide exchange factor domain superfamily [IPR023578]", "Ras guanine-nucleotide exchange factor, catalytic domain superfamily [IPR036964]", "RecQ mediated genome instability protein, N-terminal, subdomain 2 [IPR042470]", "RecQ-mediated genome instability protein 1, N-terminal, subdomain 1 superfamily [IPR044881]", "Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II [IPR009091]", "Regulatory factor, effector binding domain superfamily [IPR011256]", "Rho GDP-dissociation inhibitor domain superfamily [IPR024792]", "Rho GTPase activation protein [IPR008936]", "Rhodanese-like domain superfamily [IPR036873]", "Rhomboid-like superfamily [IPR035952]", "Riboflavin kinase domain superfamily [IPR023465]", "Riboflavin synthase-like beta-barrel [IPR017938]", "Ribokinase-like [IPR029056]", "Ribonuclease H superfamily [IPR036397]", "Ribonuclease H-like superfamily [IPR012337]", "Ribonuclease H1, N-terminal domain superfamily [IPR037056]", "Ribonuclease HII, helix-loop-helix cap domain superfamily [IPR023160]", "Ribonuclease III, endonuclease domain superfamily [IPR036389]", "Ribonuclease P/MRP subunit Rpp29 superfamily [IPR036980]", "Ribonuclease T2-like superfamily [IPR036430]", "Ribonuclease Z/Hydroxyacylglutathione hydrolase-like [IPR036866]", "Ribonucleotide reductase R1 subunit, N-terminal [IPR008926]", "Ribonucleotide reductase-like [IPR012348]", "Ribosomal L15/L27a, N-terminal [IPR027386]", "Ribosomal L18e/L15P superfamily [IPR036227]", "Ribosomal RNA-processing protein 8, N-terminal domain [IPR042036]", "Ribosomal protein L1, 3-layer alpha/beta-sandwich [IPR016095]", "Ribosomal protein L1-like [IPR023674]", "Ribosomal protein L10-like domain superfamily [IPR043141]", "Ribosomal protein L10e/L16 superfamily [IPR036920]", "Ribosomal protein L11, C-terminal domain superfamily [IPR036769]", "Ribosomal protein L11/L12, N-terminal domain superfamily [IPR036796]", "Ribosomal protein L13 superfamily [IPR036899]", "Ribosomal protein L14 superfamily [IPR036853]", "Ribosomal protein L15e core domain superfamily [IPR024794]", "Ribosomal protein L17 superfamily [IPR036373]", "Ribosomal protein L19 superfamily [IPR038657]", "Ribosomal protein L19/L19e superfamily [IPR035970]", "Ribosomal protein L19/L19e, domain 1 [IPR015972]", "Ribosomal protein L2, domain 2 [IPR014722]", "Ribosomal protein L2, domain 3 [IPR014726]", "Ribosomal protein L20, C-terminal [IPR035566]", "Ribosomal protein L21 superfamily [IPR036948]", "Ribosomal protein L22/L17 superfamily [IPR036394]", "Ribosomal protein L22e superfamily [IPR038526]", "Ribosomal protein L23/L15e core domain superfamily [IPR012678]", "Ribosomal protein L24e/L24 superfamily [IPR038630]", "Ribosomal protein L25/Gln-tRNA synthetase, N-terminal [IPR020056]", "Ribosomal protein L25/Gln-tRNA synthetase, anti-codon-binding domain superfamily [IPR011035]", "Ribosomal protein L27e superfamily [IPR038655]", "Ribosomal protein L28/L24 superfamily [IPR037147]", "Ribosomal protein L29/L35 superfamily [IPR036049]", "Ribosomal protein L3, domain 3, archaeal type superfamily [IPR044892]", "Ribosomal protein L30, ferredoxin-like fold domain superfamily [IPR036919]", "Ribosomal protein L31e domain superfamily [IPR023621]", "Ribosomal protein L32e superfamily [IPR036351]", "Ribosomal protein L35A superfamily [IPR038661]", "Ribosomal protein L36e domain superfamily [IPR038097]", "Ribosomal protein L37ae/L37e [IPR011331]", "Ribosomal protein L38e superfamily [IPR038464]", "Ribosomal protein L4 domain superfamily [IPR023574]", "Ribosomal protein L5 domain superfamily [IPR022803]", "Ribosomal protein L6, alpha-beta domain superfamily [IPR036789]", "Ribosomal protein L7/L12, C-terminal/adaptor protein ClpS-like [IPR014719]", "Ribosomal protein L7/L12, oligomerisation domain superfamily [IPR036235]", "Ribosomal protein L9, N-terminal domain superfamily [IPR036935]", "Ribosomal protein L9/RNase H1, N-terminal [IPR009027]", "Ribosomal protein P1/P2, N-terminal domain [IPR038716]", "Ribosomal protein S10 domain superfamily [IPR036838]", "Ribosomal protein S11 superfamily [IPR036967]", "Ribosomal protein S13-like, H2TH [IPR010979]", "Ribosomal protein S14/S29 [IPR043140]", "Ribosomal protein S16 domain superfamily [IPR023803]", "Ribosomal protein S17e-like superfamily [IPR036401]", "Ribosomal protein S18 superfamily [IPR036870]", "Ribosomal protein S19/S15, superfamily [IPR023575]", "Ribosomal protein S2, flavodoxin-like domain superfamily [IPR023591]", "Ribosomal protein S21e superfamily [IPR038579]", "Ribosomal protein S3, C-terminal domain superfamily [IPR036419]", "Ribosomal protein S4e, central domain superfamily [IPR038237]", "Ribosomal protein S5 domain 2-type fold [IPR020568]", "Ribosomal protein S5 domain 2-type fold, subgroup [IPR014721]", "Ribosomal protein S6 superfamily [IPR035980]", "Ribosomal protein S7 domain superfamily [IPR036823]", "Ribosomal protein S8 superfamily [IPR035987]", "Ribosomal protein S8e subdomain, eukaryotes [IPR042563]", "Ribosome maturation protein SBDS, N-terminal domain superfamily [IPR036786]", "Ribosome maturation protein Sdo1/SBDS, central domain superfamily [IPR037188]", "Ribosome-associated complex head domain superfamily [IPR042569]", "Ribulose-phosphate binding barrel [IPR011060]", "Ricin B-like lectins [IPR035992]", "RmlC-like cupin domain superfamily [IPR011051]", "RmlC-like jelly roll fold [IPR014710]", "Rof/RNase P-like [IPR023534]", "Rossmann-like alpha/beta/alpha sandwich fold [IPR014729]", "Rpb4/RPC9 superfamily [IPR038324]", "Rudiment single hybrid motif [IPR011054]", "RutC-like superfamily [IPR035959]", "RuvA domain 2-like [IPR010994]", "RuvBL1/2, DNA/RNA binding domain [IPR042487]", "S-adenosyl-L-methionine-dependent methyltransferase [IPR029063]", "S-adenosylmethionine synthetase superfamily [IPR022636]", "S15/NS1, RNA-binding [IPR009068]", "SAP domain superfamily [IPR036361]", "SAP30, C-terminal domain superfamily [IPR038291]", "SCP2 sterol-binding domain superfamily [IPR036527]", "SGNH hydrolase superfamily [IPR036514]", "SH2 domain superfamily [IPR036860]", "SH3-like domain superfamily [IPR036028]", "SKP1-like, dimerisation domain superfamily [IPR036296]", "SKP1/BTB/POZ domain superfamily [IPR011333]", "SLED domain superfamily [IPR038348]", "SMAD/FHA domain superfamily [IPR008984]", "SMCs flexible hinge superfamily [IPR036277]", "SNARE [IPR010989]", "SNF2-like, N-terminal domain superfamily [IPR038718]", "SNase-like, OB-fold superfamily [IPR035437]", "SOS response associated peptidase-like [IPR036590]", "SPOC-like, C-terminal domain superfamily [IPR016194]", "SRA-YDG superfamily [IPR036987]", "SRCR-like domain superfamily [IPR036772]", "SRP/SRP receptor, N-terminal [IPR036225]", "SRP68, N-terminal domain superfamily [IPR038253]", "SSRP1 domain superfamily [IPR038167]", "START-like domain superfamily [IPR023393]", "STAT transcription factor, DNA-binding, N-terminal [IPR012345]", "STAT transcription factor, N-terminal domain superfamily [IPR036535]", "STAT transcription factor, coiled coil [IPR015988]", "STAT1, C-terminal domain superfamily [IPR038295]", "SUI1 domain superfamily [IPR036877]", "SWAP/Surp superfamily [IPR035967]", "SWIB/MDM2 domain superfamily [IPR036885]", "Saposin-like [IPR011001]", "Scaffold protein Nfu/NifU, N-terminal domain superfamily [IPR036498]", "Scavenger mRNA decapping enzyme, N-terminal [IPR011145]", "Schlafen, AlbA_2 domain superfamily [IPR038461]", "ScpA-like, C-terminal [IPR023093]", "Sec1-like superfamily [IPR036045]", "Sec1-like, domain 1 [IPR043154]", "Sec1-like, domain 2 [IPR027482]", "Sec1-like, domain 3a [IPR043127]", "Sec23/Sec24 helical domain superfamily [IPR036175]", "Sec7 domain superfamily [IPR035999]", "Sec7, C-terminal domain superfamily [IPR023394]", "SecY domain superfamily [IPR023201]", "Sema domain superfamily [IPR036352]", "Serine carboxypeptidase S28, SKS domain [IPR042269]", "Serine-tRNA synthetase, type1, N-terminal domain superfamily [IPR042103]", "Serpin superfamily [IPR036186]", "Serpin superfamily, domain 1 [IPR042178]", "Serpin superfamily, domain 2 [IPR042185]", "Seven-hairpin glycosidases [IPR036026]", "Signal recognition particle SRP54, N-terminal domain superfamily [IPR042101]", "Signal recognition particle, SRP54 subunit, M-domain superfamily [IPR036891]", "Signal recognition particle, SRP9/SRP14 subunit [IPR009018]", "Signal recognition particle, subunit SRP19-like superfamily [IPR036521]", "Sin3 associated polypeptide p18 superfamily [IPR042534]", "Single hybrid motif [IPR011053]", "Sirtuin, catalytic core small domain superfamily [IPR026591]", "Six-bladed beta-propeller, TolB-like [IPR011042]", "Six-hairpin glycosidase superfamily [IPR008928]", "Six-hairpin glycosidase-like superfamily [IPR012341]", "Smac/DIABLO-like superfamily [IPR009062]", "Sodium/potassium-transporting ATPase subunit beta superfamily [IPR038702]", "Sodium:dicarboxylate symporter superfamily [IPR036458]", "Spermadhesin, CUB domain superfamily [IPR035914]", "Spermidine synthase, tetramerisation domain superfamily [IPR037163]", "Spt6, Death-like domain [IPR042066]", "Stathmin superfamily [IPR036002]", "Sterile alpha motif/pointed domain superfamily [IPR013761]", "Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain superfamily [IPR027477]", "Succinyl-CoA synthetase-like [IPR016102]", "Sulfatase-modifying factor enzyme superfamily [IPR042095]", "Sulfhydryl oxidase, flavin adenine dinucleotide (FAD) binding domain superfamily [IPR042568]", "TAP42/TAP46-like superfamily [IPR038511]", "TBP domain superfamily [IPR012295]", "TCP-1-like chaperonin intermediate domain superfamily [IPR027410]", "TEL2, C-terminal domain superfamily [IPR038528]", "TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily [IPR042536]", "TFIIS/LEDGF domain superfamily [IPR035441]", "TGS-like [IPR012676]", "TGS-like domain superfamily [IPR023192]", "TMEM14 superfamily [IPR044890]", "TRAF-like [IPR008974]", "TRF2-interacting telomeric protein/Rap1, C-terminal domain superfamily [IPR038104]", "TROVE domain superfamily [IPR037214]", "Talin, central domain superfamily [IPR036476]", "Tautomerase/MIF superfamily [IPR014347]", "Terpenoid cyclases/protein prenyltransferase alpha-alpha toroid [IPR008930]", "Tetrapyrrole methylase superfamily [IPR035996]", "Tetrapyrrole methylase, subdomain 1 [IPR014777]", "Tetrapyrrole methylase, subdomain 2 [IPR014776]", "Tetraspanin, EC2 domain superfamily [IPR008952]", "Tetratricopeptide-like helical domain superfamily [IPR011990]", "Tex-like domain superfamily [IPR023323]", "Tex-like protein, HTH domain superfamily [IPR023319]", "Thiamin diphosphate-binding fold [IPR029061]", "Thiolase-like [IPR016039]", "Thioredoxin-like superfamily [IPR036249]", "Threonyl/alanyl tRNA synthetase, class II-like, putative editing domain superfamily [IPR018163]", "Thymidylate synthase/dCMP hydroxymethylase superfamily [IPR036926]", "Tim10-like domain superfamily [IPR035427]", "Tma16 superfamily [IPR038356]", "Toll/interleukin-1 receptor homology (TIR) domain superfamily [IPR035897]", "Transcription Factor IIF, Rap30/Rap74, interaction [IPR011039]", "Transcription elongation factor S-II, central domain superfamily [IPR036575]", "Transcription factor EnY2 superfamily [IPR038212]", "Transcription termination and cleavage factor, C-terminal domain superfamily [IPR038192]", "Transferrin receptor-like, dimerisation domain superfamily [IPR036757]", "Transketolase C-terminal/Pyruvate-ferredoxin oxidoreductase domain II [IPR009014]", "Translation Initiation factor eIF- 4e-like [IPR023398]", "Translation elongation factor EF1A/initiation factor IF2gamma, C-terminal [IPR009001]", "Translation elongation factor EF1B/ribosomal protein S6 [IPR014717]", "Translation elongation factor eEF-1beta-like superfamily [IPR036219]", "Translation initiation factor 2, alpha subunit, C-terminal [IPR024055]", "Translation initiation factor 2, alpha subunit, middle domain superfamily [IPR024054]", "Translation initiation factor 3, subunit 12, N-terminal, eukaryotic [IPR016020]", "Translation initiation factor IF-2, domain 3 superfamily [IPR036925]", "Translation initiation factor IF2/IF5, N-terminal [IPR016189]", "Translation initiation factor IF2/IF5, zinc-binding [IPR016190]", "Translation initiation factor eIF-2B subunit alpha, N-terminal [IPR042528]", "Translation protein SH3-like domain superfamily [IPR008991]", "Translation protein, beta-barrel domain superfamily [IPR009000]", "Translin superfamily [IPR036081]", "Translin, C-terminal [IPR016069]", "Translin, N-terminal [IPR016068]", "Trimeric LpxA-like superfamily [IPR011004]", "Triosephosphate isomerase superfamily [IPR035990]", "TspO/MBR-related superfamily [IPR038330]", "Tubulin binding cofactor A superfamily [IPR036126]", "Tubulin, C-terminal [IPR023123]", "Tubulin/FtsZ, C-terminal [IPR008280]", "Tubulin/FtsZ, GTPase domain superfamily [IPR036525]", "Tubulin/FtsZ-like, C-terminal domain [IPR037103]", "Tumor necrosis factor alpha-induced protein 8-like superfamily [IPR038355]", "UBA-like superfamily [IPR009060]", "UDP-glucose/GDP-mannose dehydrogenase, C-terminal domain superfamily [IPR036220]", "UROD/MetE-like superfamily [IPR038071]", "UbiA prenyltransferase superfamily [IPR044878]", "Ubiquitin activating enzyme, alpha domain superfamily [IPR023318]", "Ubiquitin-activating enzyme E1, C-terminal domain superfamily [IPR038252]", "Ubiquitin-activating enzyme E1, FCCH domain superfamily [IPR042302]", "Ubiquitin-activating enzyme E1, SCCH domain [IPR042063]", "Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 [IPR042449]", "Ubiquitin-activating enzyme [IPR035985]", "Ubiquitin-conjugating enzyme/RWD-like [IPR016135]", "Ubiquitin-like domain superfamily [IPR029071]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 1 [IPR042522]", "Ubiquitin-like modifier-activating enzyme Atg7, N-terminal, subdomain 2 [IPR042523]", "Ufd1-like, Nn domain [IPR042299]", "Uracil-DNA glycosylase-like domain superfamily [IPR036895]", "Ureohydrolase domain superfamily [IPR023696]", "V-type ATP synthase c/d subunit, domain 3 superfamily [IPR044911]", "V-type ATP synthase subunit c/d subunit superfamily [IPR036079]", "V-type ATPase subunit C/d [IPR035067]", "V-type ATPase subunit E, C-terminal domain superfamily [IPR038495]", "VASP tetramerisation domain superfamily [IPR038023]", "VKOR domain superfamily [IPR038354]", "VPS28, C-terminal domain superfamily [IPR037206]", "VPS28, N-terminal domain superfamily [IPR038358]", "VPS9 domain superfamily [IPR037191]", "Vacuolar ATP synthase subunit C superfamily [IPR036132]", "Vacuolar protein sorting-associated protein 33, domain 3b [IPR043155]", "Vacuolar protein sorting-associated protein 35, C-terminal [IPR042491]", "Vacuolar protein sorting-associated protein IST1-like [IPR042277]", "Valyl-tRNA synthetase, tRNA-binding arm superfamily [IPR037118]", "Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain [IPR009008]", "Vanillyl-alcohol oxidase, C-terminal subdomain 2 [IPR016171]", "Vesicle transport v-SNARE, N-terminal domain superfamily [IPR038407]", "Vitamin B12-dependent methionine synthase, activation domain superfamily [IPR037010]", "Vps16, C-terminal domain superfamily [IPR038132]", "Vps53, C-terminal domain superfamily [IPR038260]", "Vta1/Callose synthase, N-terminal domain superfamily [IPR023175]", "WD40-repeat-containing domain superfamily [IPR036322]", "WD40/YVTN repeat-like-containing domain superfamily [IPR015943]", "WGR domain superfamily [IPR036930]", "WW domain superfamily [IPR036020]", "WWE domain superfamily [IPR037197]", "Winged helix DNA-binding domain superfamily [IPR036390]", "Winged helix-like DNA-binding domain superfamily [IPR036388]", "XPC-binding domain superfamily [IPR036353]", "YjeF N-terminal domain superfamily [IPR036652]", "YqgF/RNase H-like domain superfamily [IPR037027]", "ZPR1, A/B domain [IPR042451]", "ZPR1, zinc finger domain [IPR042452]", "Zinc finger C2H2 superfamily [IPR036236]", "Zinc finger, C2H2C-type superfamily [IPR036060]", "Zinc finger, CCCH-type superfamily [IPR036855]", "Zinc finger, CCHC-type superfamily [IPR036875]", "Zinc finger, FYVE/PHD-type [IPR011011]", "Zinc finger, NHR/GATA-type [IPR013088]", "Zinc finger, PARP-type superfamily [IPR036957]", "Zinc finger, RING/FYVE/PHD-type [IPR013083]", "Zinc finger, RanBP2-type superfamily [IPR036443]", "Zinc finger, Sec23/Sec24-type superfamily [IPR036174]", "Zinc finger, ZZ-type superfamily [IPR043145]", "Zinc-binding ribosomal protein [IPR011332]", "dUTPase-like superfamily [IPR036157]", "eRF1, domain 1 [IPR024049]", "eRF1, domain 2 superfamily [IPR042226]", "p53-like tetramerisation domain superfamily [IPR036674]", "p53-like transcription factor, DNA-binding [IPR008967]", "p53/RUNT-type transcription factor, DNA-binding domain superfamily [IPR012346]", "rRNA adenine dimethylase-like, C-terminal [IPR023165]", "ssDNA-binding transcriptional regulator [IPR009044]", "tRNA (guanine-N1-)-methyltransferase, N-terminal [IPR029026]", "tRNA methyltransferase TRM10-type domain superfamily [IPR038459]", "tRNA methyltransferase, Trm1, C-terminal [IPR042296]", "tRNA modification GTPase MnmE domain 2 [IPR027368]", "tRNA-splicing ligase RtcB-like superfamily [IPR036025]", "von Willebrand factor A-like domain superfamily [IPR036465]"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP13", "AKAP17A", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALKBH5", "ALYREF", "AMFR", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOC1", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL8B", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARVCF", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5H", "ATP5J", "ATP5O", "ATP6", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATP6V1H", "ATPAF2", "ATRX", "ATXN10", "AURKA", "AURKB", "B3GAT3", "B4GALT1", "B4GALT3", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCAS3", "BCAT2", "BCKDK", "BCL2L12", "BCL2L13", "BCR", "BCS1L", "BECN1", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BOLA2*", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BZW1", "BZW2", "C10orf76", "C1QBP", "C2CD2", "C2CD2L", "C2CD5", "C3orf33", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC7", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPV", "CEP170", "CEPT1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1B", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHORDC1", "CHTF18", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNN3", "CNNM4", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "COA7", "COASY", "COG8", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPZ1", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLST", "DMAC2", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP9", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3B", "EIF3E", "EIF3G", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC7", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC2", "EXOC3", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM120A", "FAM129B", "FAM173A", "FANCG", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FBL", "FDFT1", "FDPS", "FDXR", "FEM1A", "FEN1", "FERMT2", "FH", "FHOD1", "FIGNL1", "FIS1", "FKBP10", "FKBP14", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FN3KRP", "FNBP1", "FNBP4", "FNDC3A", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCLM", "GCN1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GNS", "GOLPH3", "GOLPH3L", "GOPC", "GORASP2", "GOSR2", "GOT1", "GOT2", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPRASP2", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2I", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGFL2", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HMBS", "HMCES", "HMG20A", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDI1", "IFIT5", "IFT27", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMPACT", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS4", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRS4", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAM3", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDM1A", "KDM1B", "KDM2A", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "LACTB", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC45", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LYAR", "LYPLA1", "LYSMD3", "LZIC", "M6PR", "MACF1", "MAD2L1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1A", "MAP2K1", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED21", "MED25", "MEPCE", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPG", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL38", "MRPL39", "MRPL4", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS25", "MRPS27", "MRPS5", "MRPS6", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTERF3", "MTF2", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYEF2", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKIPSD", "NCL", "NCOA5", "NDRG3", "NDUFA10", "NDUFA2", "NDUFA9", "NDUFAF3", "NDUFAF7", "NDUFS1", "NDUFS3", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK3", "NEK9", "NELFE", "NENF", "NFATC2IP", "NFKBIL1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL8", "NOL9", "NOM1", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUP133", "NUP153", "NUP155", "NUP188", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP98", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PAPSS1", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PAX6", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCMT1", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD11", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PI4KB", "PIAS2", "PICALM", "PIGG", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRKAA2", "PRKACA", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMG2", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PYCR1", "PYCR2", "PYCR3", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "R3HCC1", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REPS1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIPK1", "RMDN1", "RMDN2", "RMDN3", "RMI1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS4X", "RPS5", "RPS6KA1", "RPS6KA3", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP12", "RRP7A", "RRP8", "RRP9", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN4IP1", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SBDS", "SCAF11", "SCAF4", "SCAF8", "SCCPDH", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61G", "SEC63", "SEH1L", "SEL1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3B1", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMS", "SMU1", "SMYD3", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPATS2L", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STARD3", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STUB1", "STX10", "STX12", "STX4", "STX5", "STX6", "STX7", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "TAB1", "TAF15", "TAGLN2", "TALDO1", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "THADA", "THEM6", "THOC1", "THOC3", "THOC6", "THOP1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMM10B", "TIMM13", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TMA16", "TMED2", "TMED5", "TMED7", "TMEM115", "TMEM131", "TMEM14C", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNFAIP8", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52L2", "TPI1", "TPM4", "TPP1", "TPP2", "TPRKB", "TPT1", "TRA2A", "TRA2B", "TRAP1", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBL5", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UCK2", "UFC1", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIPAS39", "VIRMA", "VKORC1L1", "VPS13D", "VPS16", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VRK1", "VRK2", "VTA1", "VWA8", "WAPL", "WARS", "WARS2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR89", "WDR91", "WFS1", "WIZ", "WNK1", "WRAP73", "WRN", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YKT6", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZDHHC13", "ZFPL1", "ZFR", "ZFYVE16", "ZMAT2", "ZMYM1", "ZMYND8", "ZNF281", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZNF687", "ZPR1"], "leading_proteins": ["ABCB7", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACP6", "ACTN1", "ACTN4", "ADD3", "ADK", "AFG3L2", "AGK", "AIFM1", "AKT1", "AKT2", "ALDH1B1", "ANAPC2", "ANAPC7", "ANKLE2", "AP1B1", "APLP2", "APP", "ARHGAP1", "ARHGAP10", "ARHGEF1", "ARID1A", "ARID2", "ARIH1", "ATL2", "ATP2A2", "B4GALT1", "B4GALT3", "BAG6", "BAIAP2", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCKDK", "BCR", "CADM1", "CAMK2G", "CAPN2", "CAPN5", "CASK", "CBX1", "CBX3", "CBX5", "CBX8", "CD2BP2", "CDC42BPB", "CDH2", "CDK5RAP1", "CENPV", "CERS2", "CHD1", "CHD4", "CHD7", "CLSTN3", "CLUH", "COPS2", "CRTAP", "CTNNAL1", "CTSA", "CUL2", "CUL3", "CUL4B", "CUL5", "CYB5D2", "DCP1B", "DCTN1", "DHCR24", "DIAPH1", "DIAPH3", "DNAJA2", "DNAJB12", "DNAJC1", "DNAJC10", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNM3", "DOCK1", "DOCK7", "DYNC2H1", "ECE1", "EEA1", "EEF1A2", "EEF1D", "EFCAB14", "EIF2S3", "EIF5A", "ELMO2", "ENDOG", "EPB41L2", "EPHA7", "EPHX1", "ERC1", "ERCC6L", "EWSR1", "EXOSC2", "EXOSC3", "EZR", "FAM129B", "FANCG", "FERMT2", "FHOD1", "FLOT1", "FMR1", "FNBP1", "FOXRED1", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "GAA", "GAK", "GLA", "GLB1", "GLT8D1", "GNL3L", "GNS", "GPKOW", "GSPT1", "GSR", "GUSB", "HBS1L", "HDAC2", "HEBP2", "HELLS", "HERC2", "HINT3", "HLA-C", "HLA-F", "HLTF", "HMGB2", "HOOK2", "HS1BP3", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "IGF2BP1", "IGF2BP2", "IGF2R", "ILF2", "ILF3", "INPP4A", "IQGAP3", "ISOC1", "ISY1", "ITGA2", "ITSN2", "JAM3", "KCTD21", "KDM1B", "KDM2A", "KHDRBS1", "KHSRP", "KIAA0319L", "KIF11", "KIF20A", "KIF22", "KIF23", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIN", "KRR1", "LANCL2", "LEMD3", "LIG3", "LIN28B", "LMNA", "LMNB2", "LNPEP", "M6PR", "MACF1", "MAPRE2", "MAVS", "MCAT", "MED25", "MFSD8", "MGEA5", "MICU1", "MICU2", "MID1", "MORF4L1", "MOSPD2", "MPP2", "MPP5", "MPRIP", "MRM3", "MRPL13", "MRPL19", "MRPL2", "MRPL22", "MRPL24", "MRPS6", "MSN", "MTA1", "MTCH2", "MTG1", "MTIF2", "MTPAP", "MTX1", "MYCBP2", "MYH10", "MYH14", "MYH9", "MYO1D", "NAA16", "NAGLU", "NAP1L4", "NASP", "NENF", "NOVA2", "NPEPPS", "NRDE2", "NSD1", "NSD2", "NSD3", "NSF", "NUCB1", "NUCB2", "OSBPL3", "PAK2", "PAPOLA", "PCDH7", "PCYOX1", "PDK1", "PDK3", "PGRMC2", "PHF10", "PI4KA", "PIGG", "PITRM1", "PKN2", "PLA2G15", "PMPCA", "PMS1", "POLR1A", "POLR3A", "POLRMT", "POMGNT2", "PPFIA1", "PPOX", "PPP1R10", "PPP4R3A", "PPT1", "PPT2", "PRCP", "PRPF3", "PRPF31", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD11", "PTPRF", "QKI", "RANBP2", "RAPGEF2", "RARS", "RBM10", "RBM22", "RBM5", "RCN2", "RFC3", "ROCK1", "ROCK2", "RPL10", "RPL14", "RPL15", "RPL21", "RPL26", "RPL37", "RPL37A", "RPL6", "RPL7L1", "RPL8", "RPS24", "RPS4X", "RRM2B", "RSL24D1", "RTCA", "SCAF11", "SCP2", "SCPEP1", "SDF4", "SEC23B", "SEC63", "SET", "SLC16A1", "SLC18B1", "SLC25A10", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A33", "SLC25A42", "SLC25A44", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMC2", "SMC3", "SMC4", "SMCHD1", "SNX27", "SNX4", "SNX8", "SNX9", "SPATA5", "SPECC1", "SPHK2", "SPTAN1", "SPTBN1", "STAT1", "STAT3", "STK4", "STRBP", "STX10", "STX6", "STX7", "SUPT5H", "SUPT6H", "SV2A", "SYNJ2BP", "TCERG1", "TCF25", "TDRKH", "TEX264", "THEM6", "THOP1", "TMEM131", "TMPO", "TMTC3", "TOP2A", "TRAP1", "TRIM13", "TRIM21", "TRIM27", "TRIM32", "TSPAN3", "TTC19", "TTC26", "TTC37", "TTC38", "TTF2", "TUBGCP3", "TUFM", "UBE4B", "UBTF", "UQCRC2", "USP15", "USP22", "USP38", "USP47", "USP48", "USP7", "UTRN", "VDAC1", "VPS33B", "XRCC6", "ZC3H15", "ZC3H18", "ZC3H4", "ZCCHC11"]} \ No newline at end of file diff --git a/interpro_ptm/advanced/idx2term.json b/interpro_ptm/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/basic/idx2term.json b/interpro_ptm/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/interpro_ptm/basic/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/interpro_ptm/consensus.joblib b/interpro_ptm/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..7a354605d17b8d272f32fe69314fb34302769d0f --- /dev/null +++ b/interpro_ptm/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c59db96e87ec46c3818c235318cf86fe8917c42a0e1be2e008cbcf4af9a71cc9 +size 80913 diff --git a/interpro_ptm/df_merge.tsv b/interpro_ptm/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/interpro_ptm/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/interpro_ptm/metrics.json b/interpro_ptm/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ffa4ee83a4344d7daee18f64bd225bb507ce60e3 --- /dev/null +++ b/interpro_ptm/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 2.75 +} \ No newline at end of file diff --git a/interpro_ptm/paths.json b/interpro_ptm/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..76b3a5dd6b2f413508a63cc80f1c7712fb0189e3 --- /dev/null +++ b/interpro_ptm/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_ptm/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/interpro_ptm/result.tsv b/interpro_ptm/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..cadc157810566f6914bd9cff27d7c630fbb7ace9 --- /dev/null +++ b/interpro_ptm/result.tsv @@ -0,0 +1,2 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +P-type ATPase, phosphorylation site [IPR018303] 0.7327228967970489 1.5935355599975791 0.1110400975612098 0.3755053987783491 0.1258322957736783 6 P16615 1 diff --git a/interpro_ptm/selections.json b/interpro_ptm/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..4fbce02acf2f8df8bcfda42f608d455e018dcea6 --- /dev/null +++ b/interpro_ptm/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["EGF-type aspartate/asparagine hydroxylation site [IPR000152]", "P-type ATPase, phosphorylation site [IPR018303]", "Phosphopantetheine attachment site [IPR006162]", "Translation elongation factor, IF5A, hypusine site [IPR019769]"], "available_proteins": ["ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "EIF5A", "FASN", "LDLR", "NOTCH2", "SLIT2"], "leading_proteins": ["ATP2A2"]} \ No newline at end of file diff --git a/interpro_repeat/advanced/idx2term.json b/interpro_repeat/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..6dce773863970e13dd9ed6c0019ab4c4e97de280 --- /dev/null +++ b/interpro_repeat/advanced/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]"} \ No newline at end of file diff --git a/interpro_repeat/advanced/plot_0.png b/interpro_repeat/advanced/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..edd2a7662bcb107d2699806116600edd21762d8c --- /dev/null +++ b/interpro_repeat/advanced/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:244189a60ab766a20afdd052fe6542f51c7aec602536f5fdad361dede5e042e0 +size 192046 diff --git a/interpro_repeat/basic/idx2term.json b/interpro_repeat/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..89347332fd727e794f5dc31a862dff01327a7f4e --- /dev/null +++ b/interpro_repeat/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Mitochondrial substrate/solute carrier [IPR018108]", "1": "Tetratricopeptide repeat [IPR019734]"} \ No newline at end of file diff --git a/interpro_repeat/basic/plot_0.png b/interpro_repeat/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..9a23e6896e02e59dfed4f228ede0cc8710e46c6f --- /dev/null +++ b/interpro_repeat/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:55a96ab3ea6929d4d819d0d8b84ac1f84084914eaa1fcfbbe23c23ead76e3913 +size 144805 diff --git a/interpro_repeat/basic/plot_1.png b/interpro_repeat/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..9ebbc28a1b4aeab91334881bcde007f5b6356cb3 --- /dev/null +++ b/interpro_repeat/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4b60edeeea62a130fcc4c33046abd7cb347a46cd060da3a1a41f13fa83479911 +size 151503 diff --git a/interpro_repeat/consensus.joblib b/interpro_repeat/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..e7e3e303d4f047172398531fff04b3feb9f71175 --- /dev/null +++ b/interpro_repeat/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:508d5fa1c18eb20c9b0cdec40b1941f4633bb39ae3daa5c9fe34a63adc6b1429 +size 97313 diff --git a/interpro_repeat/df_merge.tsv b/interpro_repeat/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e19d9126752345e5e1a303668205e124cc626af5 --- /dev/null +++ b/interpro_repeat/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Mitochondrial substrate/solute carrier [IPR018108] 10 24 2.2244726492984945 0.0261166606973624 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 1.0 0.1644315705571846 0.3050454458143302 0.6053596540060717 0.0094203676276074 diff --git a/interpro_repeat/metrics.json b/interpro_repeat/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..015c3ac593672304c800bd469c6728bc38984138 --- /dev/null +++ b/interpro_repeat/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 80, + "title": "Average number of proteins per term", + "value": 5.7125 +} \ No newline at end of file diff --git a/interpro_repeat/paths.json b/interpro_repeat/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..df028f5a5d90dd1e0cae30d0762b1a245cb8fb3b --- /dev/null +++ b/interpro_repeat/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/interpro_repeat/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/interpro_repeat/result.tsv b/interpro_repeat/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..105e9d3f42d55d06caec5f8f1d3ddab0cf142021 --- /dev/null +++ b/interpro_repeat/result.tsv @@ -0,0 +1,14 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Mitochondrial substrate/solute carrier [IPR018108] 0.6049861491068858 2.2244726492984945 0.0261166606973624 0.8796198453904525 0.0691383377798375 24 Q9BSK2,Q86VD7,Q70HW3,Q9UBX3,Q96H78,Q9BQT8,O43772,Q9HC21,Q9Y619,Q9Y6C9 10 +Protein prenyltransferase, alpha subunit [IPR002088] 0.8547102444383388 2.1026826596929222 0.0354935188445653 0.9444847852587744 0.0845061021513602 2 P49354 1 +Importin repeat 4 [IPR041653] 0.8146113705026087 1.9294819624972257 0.0536710572082816 0.9878837052335524 0.1047240140649398 2 O00410 1 +Importin repeat 6 [IPR041389] 0.8146113705026087 1.9294819624972257 0.0536710572082816 0.9878837052335524 0.1047240140649398 2 O00410 1 +Spectrin repeat [IPR002017] 0.6988818973535541 1.84046983049378 0.0656992896093919 0.995645539805288 0.1251415040178894 9 P12814,Q13813,P46939,O43707 4 +FG-GAP repeat [IPR013517] 0.7151881351277088 1.4908027346554398 0.1360132936031362 0.9999916715376688 0.2133541860441352 2 P17301 1 +Integrin alpha beta-propellor [IPR013519] 0.7151881351277088 1.4908027346554398 0.1360132936031362 0.9999916715376688 0.2133541860441352 2 P17301 1 +Spectrin/alpha-actinin [IPR018159] 0.5250661644285085 1.1301309227376282 0.2584210615023496 0.9999999999590182 0.3626962266699644 11 P12814,Q13813,P46939,O43707 4 +Kinesin light chain repeat [IPR015792] 0.62372974457566 1.0832662339523982 0.2786902682658163 0.9999999999955358 0.3844003700218156 2 Q07866 1 +HEAT repeat [IPR000357] 0.5129585876707144 0.7954615118240908 0.4263450908957298 1.0 0.5329313636196622 7 Q8TF05,O60518,O00410 3 +Leucine rich repeat 4 [IPR025875] 0.5770381062715453 0.6362387583990354 0.5246208145208495 1.0 0.6456871563333533 3 Q9UFC0 1 +Regulator of chromosome condensation, RCC1 [IPR000408] 0.410486874926181 0.2460003722185063 0.8056819443659062 1.0 0.882939117113322 5 O75592 1 +Tetratricopeptide repeat [IPR019734] 0.253508701520526 0.0942268911748157 0.9249289237350355 1.0 0.9486450499846518 50 Q96RK4,P49321,Q9UJX3,Q6ZXV5,Q6N069,O15287,Q6PGP7,Q6DKK2,A0AVF1 9 diff --git a/interpro_repeat/selections.json b/interpro_repeat/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b921e81e5f138d0a1f53c979f77876016ca43f2e --- /dev/null +++ b/interpro_repeat/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Ankyrin repeat [IPR002110]", "Annexin repeat [IPR018502]", "Armadillo [IPR000225]", "Atypical Arm repeat [IPR032413]", "BIR repeat [IPR001370]", "Beta-propeller repeat TECPR [IPR006624]", "BspA type Leucine rich repeat region [IPR026906]", "Calponin repeat [IPR000557]", "Cation-independent mannose-6-phosphate receptor repeat [IPR000479]", "Chromosome region maintenance repeat [IPR041123]", "Clathrin, heavy chain, propeller repeat [IPR022365]", "Clathrin, heavy chain/VPS, 7-fold repeat [IPR000547]", "Collagen triple helix repeat [IPR008160]", "Cysteine-rich Golgi apparatus protein 1 repeat [IPR001893]", "Cysteine-rich Golgi apparatus protein 1 repeat, eukaryote [IPR017873]", "Exportin-1, repeat 2 [IPR041235]", "Exportin-1, repeat 3 [IPR040485]", "FG-GAP repeat [IPR013517]", "Filamin/ABP280 repeat [IPR001298]", "Filamin/ABP280 repeat-like [IPR017868]", "Fis1, C-terminal tetratricopeptide repeat [IPR028061]", "Fis1, N-terminal tetratricopeptide repeat [IPR028058]", "G-protein beta WD-40 repeat [IPR020472]", "GTF2I-like repeat [IPR004212]", "HAT (Half-A-TPR) repeat [IPR003107]", "HEAT repeat [IPR000357]", "HEAT repeat associated with sister chromatid cohesion protein [IPR026003]", "HEAT, type 2 [IPR021133]", "HUWE1/Rev1, ubiquitin binding region [IPR025527]", "Hexapeptide repeat [IPR001451]", "Hs1/Cortactin [IPR003134]", "Importin repeat 4 [IPR041653]", "Importin repeat 6 [IPR041389]", "Importin repeat [IPR040928]", "Integrin alpha beta-propellor [IPR013519]", "KI67R [IPR012568]", "Kelch repeat type 1 [IPR006652]", "Kelch repeat type 2 [IPR011498]", "Kinesin light chain repeat [IPR015792]", "LDLR class B repeat [IPR000033]", "Leucine rich repeat 4 [IPR025875]", "Leucine-rich repeat [IPR001611]", "Leucine-rich repeat, cysteine-containing subtype [IPR006553]", "Leucine-rich repeat, typical subtype [IPR003591]", "Low-density lipoprotein (LDL) receptor class A repeat [IPR002172]", "Mbt repeat [IPR004092]", "Microtubule associated protein, tubulin-binding repeat [IPR001084]", "Mitochondrial substrate/solute carrier [IPR018108]", "NHL repeat [IPR001258]", "Neuraxin/MAP1B repeat [IPR000102]", "P120R repeat [IPR012586]", "PBS lyase HEAT-like repeat [IPR004155]", "PFTB repeat [IPR001330]", "PQ-loop repeat [IPR006603]", "Paired amphipathic helix [IPR003822]", "Parallel beta-helix repeat [IPR006626]", "Pentatricopeptide repeat [IPR002885]", "Plectin repeat [IPR001101]", "Plexin repeat [IPR002165]", "Proteasome/cyclosome repeat [IPR002015]", "Protein of unknown function DM15 [IPR006607]", "Protein prenyltransferase, alpha subunit [IPR002088]", "Proteinase inhibitor I27, calpastatin [IPR001259]", "Pumilio RNA-binding repeat [IPR001313]", "Putative TPR-like repeat [IPR031545]", "Pyrrolo-quinoline quinone repeat [IPR002372]", "RNA helicase p68 repeat [IPR012587]", "RNA polymerase II, heptapeptide repeat, eukaryotic [IPR000684]", "Regulator of chromosome condensation, RCC1 [IPR000408]", "Ribonuclease inhibitor, leucine rich repeat cap [IPR041302]", "Sel1-like repeat [IPR006597]", "Spectrin repeat [IPR002017]", "Spectrin/alpha-actinin [IPR018159]", "Tetratricopeptide repeat 1 [IPR001440]", "Tetratricopeptide repeat 2 [IPR013105]", "Tetratricopeptide repeat [IPR019734]", "Vesicle tethering protein p115, armadillo tether-repeat [IPR041209]", "WD40 repeat [IPR001680]", "Wolframin, Sel1-like repeat [IPR045458]", "Zinc finger, C2H2C-type [IPR002515]"], "available_proteins": ["AAAS", "AAMP", "ACTN1", "ACTN4", "AGAP3", "AIP", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKHD1", "ANKRD17", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP2B1", "ARMC6", "ARMCX3", "ARVCF", "ASPH", "BBS4", "BIRC6", "BOP1", "BRAT1", "BUB3", "CABIN1", "CAST", "CD320", "CDC20", "CDC23", "CDC27", "CHAF1B", "CKAP5", "CLASP1", "CLPB", "CLTC", "CNN3", "COA7", "COLEC12", "COPA", "COPB2", "CORO1B", "CORO1C", "CORO7", "CRNKL1", "CSTF1", "CSTF3", "CTNNB1", "CTNND1", "CTR9", "CTTN", "DCAF13", "DCAF7", "DCAF8", "DDX5", "DNAAF5", "DNAJC3", "DNAJC7", "DOHH", "DSP", "DST", "DYNC1I2", "EDC4", "EED", "EIF2B5", "EIF3I", "ELP2", "EMC1", "EMC2", "EML4", "EPPK1", "ERBIN", "FANCG", "FEM1A", "FIS1", "FKBP4", "FKBP5", "FKBP8", "FLII", "FLNA", "FLNB", "FLNC", "FNTA", "GCN1", "GEMIN5", "GLG1", "GLS", "GMPPA", "GMPPB", "GRWD1", "GTF2I", "GTF3C2", "GTF3C3", "HCFC1", "HECTD1", "HERC2", "HUWE1", "IFIT5", "IGF2R", "ILK", "INTS4", "IPO4", "IPO5", "ITGA2", "ITGAV", "JUP", "KAT7", "KDELC2", "KDM2A", "KEAP1", "KIAA1468", "KIDINS220", "KLC1", "KLC2", "KLHDC4", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "LARP1", "LDLR", "LLGL1", "LRBA", "LRCH2", "LRPPRC", "LRRC1", "LRRC40", "LRRC45", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "MACF1", "MAP1B", "MAP4", "MAU2", "MKI67", "MPDU1", "MRPS27", "MTCH1", "MTCH2", "MTPN", "MYCBP2", "NAA15", "NAA16", "NASP", "NEK9", "NFKBIL1", "NHLRC2", "NIPBL", "NISCH", "NLE1", "NOL10", "NOP2", "NOP9", "NOTCH2", "NUDT12", "NUP214", "NUP37", "NUP43", "NXF1", "OGT", "P4HA1", "P4HA2", "PAFAH1B1", "PAK1IP1", "PDCD11", "PEX5", "PHIP", "PIK3R4", "PLAA", "PLEC", "PLRG1", "PLXNB2", "POLR2A", "PPID", "PPP1R12A", "PPP1R7", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP4R1", "PPP5C", "PPWD1", "PREB", "PRKCSH", "PRPF19", "PRPF4", "PRPF6", "PSMD1", "PSMD10", "PSMD2", "PTCD1", "PTCD3", "PUM3", "PWP1", "PWP2", "RABGGTA", "RABGGTB", "RACK1", "RAE1", "RAI14", "RANBP2", "RANBP6", "RANGAP1", "RAP1GDS1", "RBBP4", "RBBP5", "RBBP7", "RCC1", "RCC2", "RNH1", "RPAP3", "RRP9", "RSU1", "SART3", "SCML2", "SCRIB", "SEC13", "SEC31A", "SEH1L", "SEL1L", "SGTA", "SHCBP1", "SHOC2", "SIN3A", "SKP2", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLIT2", "SMU1", "SNRNP40", "SNRPA1", "SPTAN1", "SPTBN1", "SPTBN2", "SRP72", "STIP1", "STRAP", "STRN", "STUB1", "SUGT1", "SYNE2", "TAGLN2", "TBL1XR1", "TBL2", "TBL3", "TEX10", "TGFBRAP1", "THOC3", "THOC6", "TLE3", "TMTC3", "TOMM34", "TOMM70", "TPBG", "TRIM32", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC4", "TTC7B", "UNC45A", "USO1", "UTP15", "UTP18", "UTP4", "UTP6", "UTRN", "VPS18", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR89", "WDR91", "WFS1", "WRAP73", "XAB2", "XPO1", "ZDHHC13"], "leading_proteins": ["ACTN1", "ACTN4", "ANAPC7", "BBS4", "FANCG", "FNTA", "IPO5", "ITGA2", "KLC1", "LRWD1", "MTCH2", "MYCBP2", "NAA16", "NASP", "PPP4R1", "RANBP6", "SLC25A10", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A33", "SLC25A42", "SLC25A44", "SPTAN1", "TMTC3", "TTC19", "TTC26", "TTC37", "UTRN"]} \ No newline at end of file diff --git a/msigdb_gobp/advanced/idx2term.json b/msigdb_gobp/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..54bedf5cfde35ed4e6802c9afd22a2bf59296e85 --- 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0000000000000000000000000000000000000000..6e3f0cf91fde0f223fdf177e819131b91fcf0b6c --- /dev/null +++ b/msigdb_gobp/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4d12399940e05f1e1536f307f4b4be911398fb99e227698d7421e6fa2dc2da20 +size 700960 diff --git a/msigdb_gobp/df_merge.tsv b/msigdb_gobp/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..8778c8a8c95ce830b0d322a272449b14050dc7ce --- /dev/null +++ b/msigdb_gobp/df_merge.tsv @@ -0,0 +1,213 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Organic acid transport 15 53 3.2169020606394807 0.0012958282596384 16.199029126213592 46.1626213592233 1.6912598339530378 0.23494744574913 7.685833584742487 5.405881453891157 1.4084922190667013 0.315570201131532 1.0 0.0038407696470514 0.0019158686678622 0.0017480864507818 0.0009851538934748 +Positive regulation of cytokine production 19 67 3.073877781514328 0.0021129597534974 12.405339805825244 59.609223300970875 -0.0364877020837616 0.713460389026544 5.631333166670799 6.081183167536312 0.6538776209656336 0.2877617242618037 1.0 0.2424540817316537 0.2965849437799202 0.0532242531221608 0.0039959833902311 +Signal transduction by p53 class mediator 8 50 2.989005817904187 0.002798868022501 12.148058252427184 45.439320388349515 -0.1674964876877734 0.6658753107795011 6.663545305274184 5.000359940857058 0.7233121111481908 0.292752020758435 0.1354937691535878 0.1310211430713912 0.1352243419874974 0.4057604474152967 0.204942381327463 +Organic anion transport 22 56 2.947081804897515 0.0032078832748594 18.575242718446603 46.57281553398058 1.6158560948583975 0.2692356013040078 9.46386426798458 5.9518324529926545 1.7470285445738305 0.3371920110610632 1.0 0.0300520949649006 0.0024633825153555 0.0232625208838642 0.0103209749302633 +Lytic vacuole organization 13 32 2.94300553477562 0.0032504260700367 8.677184466019417 23.79368932038835 1.067589638534915 0.1668002350701783 2.8744208086829883 3.077266940940983 2.0111064761459874 0.2496786569477077 1.0 0.2471994937249445 0.0193203782926452 0.0005673930602398 7.610081655000039e-07 +Positive regulation of immune system process 34 129 2.917267887286333 0.0035311235523745 24.063106796116504 111.55825242718448 0.0014586405879444 0.7484751661806336 8.418420513377251 11.253004123360045 0.6663856016863496 0.2941180973009932 0.0607205603481945 0.031967030939157 0.0098708668940291 0.0411503135300094 0.1115723093247226 +Intrinsic apoptotic signaling pathway by p53 class mediator 2 19 2.8921516379023013 0.0038261323027704 4.264563106796117 17.20145631067961 0.1074412832507753 0.6478034147207774 2.472255083415513 1.871009751660768 0.6767489333374698 0.2669423048478566 0.0639068253026823 0.0333019544595367 0.0201824597439383 0.1820516573570916 0.1743861197591294 +Positive regulation of nf kappab transcription factor activity 11 32 2.847519541283169 0.0044061389020819 6.12378640776699 26.410194174757283 0.2523076203223285 0.632860590800981 3.308816881947663 3.568904670178294 0.7917089156036211 0.3125202136006775 1.0 0.0643379769398232 0.0097621950354221 0.0194272316030456 0.0010815371106456 +Anion transport 31 84 2.781915897093492 0.0054039041952496 26.953883495145632 69.53155339805825 1.854216838065017 0.2425457725148559 12.138973160217668 8.434296289414672 2.014686633079497 0.3448588040224388 1.0 0.0142646004278545 0.0001156515925902 0.0011088792292421 0.0002841419538423 +Carboxylic acid transport 7 38 2.7627288877296485 0.0057320356180525 12.351941747572816 33.69417475728155 1.517249458545343 0.2522623764771551 6.23371050940395 4.11174791553619 1.419876490432768 0.3135855212793009 1.0 0.0131234591400192 0.0004784923631454 0.0038170983466483 0.0129452724374584 +Regulation of lymphocyte activation 8 58 2.755988875979018 0.0058514987010116 11.79126213592233 53.939320388349515 -0.0403403309035048 0.6613939899714961 4.794831497208694 5.719894384613908 0.769375886055445 0.3104578263686236 0.2064534250313497 0.0775528091516589 0.0040220064650848 0.0712998557368483 0.2328538017677676 +Organic acid transmembrane transport 10 35 2.751664881363741 0.0059293162888811 12.37621359223301 29.983009708737864 1.9038035525846064 0.1759244630123113 6.520447095353999 3.550222565141749 1.416714921004232 0.2641413901650407 1.0 0.0543724481878489 0.0070126150189725 0.0006639209739305 0.0016116153879735 +Membrane lipid metabolic process 13 44 2.7454731332926507 0.0060423714727066 15.813106796116504 37.71116504854369 1.423850539998867 0.1808469841706369 6.252884620395072 4.742042041181393 2.289538519382486 0.2724480316274368 1.0 0.4342482165093504 0.0273655249406893 0.0024438008469359 0.0020217277453714 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 2 12 2.7400022258451764 0.006143876829088 2.6189320388349513 10.70631067961165 0.4019190203209479 0.547446240999534 1.7798578609231743 1.3683875354472868 0.7841948756424657 0.2872025542872468 0.036092947251902 0.0110614955842043 0.0040337600577914 0.0479498850625808 0.228153712059568 +Cell recognition 6 26 2.712014803345136 0.0066875606168268 5.29126213592233 22.859223300970875 0.9056944851933356 0.3618031966115522 2.859598274322472 2.538937048941188 0.9847101891513528 0.3060121099700091 0.0639068253026823 0.0333019544595367 0.0201824597439383 0.0593060830293246 0.0278547210480151 +Regulation of leukocyte apoptotic process 4 15 2.708111296269637 0.0067667325998532 2.936893203883495 11.74514563106796 0.2085778692691842 0.4643574261341155 1.8264236522577744 2.223135354411492 1.0583074377406043 0.2953853498886979 0.0454466093944714 0.0173338143393145 0.0007148849576337 0.0035757213036434 0.0562285166700403 +Transmembrane receptor protein serine threonine kinase signaling pathway 12 54 2.705191192284207 0.0068265086404599 10.631067961165048 46.15291262135922 0.2006852178393374 0.6675090539046344 4.897969246836294 6.113284616160956 0.8079382077361186 0.3228563247928272 1.0 0.2407056305689534 0.2939807277706537 0.0518693797078321 0.1719373090773397 +Endocytosis 35 139 2.687989807314321 0.0071883590830934 25.6626213592233 116.14077669902912 0.4088637809343856 0.6347066552957155 9.675324480764845 15.608206311139906 1.1645342915127963 0.3689266363473043 0.3176338069632476 0.0231824863324857 0.0176162049063519 0.0019123778049159 1.4261873007873875e-05 +Protein localization to lysosome 5 18 2.656356131934626 0.0078990147157549 3.5364077669902914 14.37621359223301 0.6191344010889903 0.3619681772746835 2.0811532251007954 2.18038858944462 1.1869570048706093 0.3022181269423334 1.0 0.1604648724397155 0.2983459236646945 0.0591065206713347 0.0082637154660588 +Positive regulation of immune effector process 16 43 2.654071914493613 0.0079526876027438 8.555825242718447 35.949029126213595 0.0678048026524438 0.6505712975954121 3.701126835567114 3.561501814390798 0.7866101291390383 0.3084477872964711 1.0 0.0901677189318956 0.0817709134109805 0.004283045532937 0.0020058581081862 +Anion transmembrane transport 22 50 2.6538297626689755 0.0079583966150884 18.02912621359223 42.29854368932039 1.9137296804814252 0.1915609440243116 8.771596162415214 5.032004157423188 1.8922368499585025 0.2935375719655638 1.0 0.0974060227674832 0.0042276675326381 0.0185833384002977 0.0010343300884568 +Positive regulation of cell activation 17 47 2.6311929557248948 0.0085085712388426 9.66504854368932 41.58980582524272 -0.0344461667002542 0.6127678592935748 3.990819774604169 3.7854079772897897 0.9017662407322792 0.3302397387818446 0.1569948284742302 0.1685497024919858 0.0037828847627916 0.0046989291352391 0.0207090421591844 +Cytokine production 25 112 2.619640125342265 0.0088022601708579 18.97087378640777 96.13106796116504 0.0824735848580317 0.7508975178485808 7.48909409104055 11.178920255675855 0.680456448776925 0.3062861740716413 0.3037812523921665 0.0188952693193902 0.0375855673372754 0.0565895018988717 0.0185335080657586 +Regulation of dna damage response signal transduction by p53 class mediator 2 11 2.595645000331399 0.0094413556572425 2.0825242718446604 10.330097087378642 0.5812744987463578 0.5053889294693675 1.7703012296176135 1.2139028728645462 0.7579316680421853 0.2843065963819335 1.0 0.1155957163384056 0.2202973788945578 0.1292409073430241 0.1303826157459173 +Regulation of lymphocyte apoptotic process 2 9 2.590621536522432 0.0095802786219705 2.029126213592233 7.381067961165049 0.4739111260724032 0.458828678896727 1.5277771827044868 1.703203955440417 1.0212880846326546 0.3148137372778026 0.0277087127163546 0.0065631621549981 0.0018516158363228 0.0239571113561098 0.1303826157459173 +Pigment metabolic process 4 31 2.5516277957939653 0.0107220994093213 6.730582524271845 27.429611650485437 0.7330558837492486 0.3938325994367372 3.1680652652278396 2.973572406869117 1.1788232115476622 0.3357800616079686 0.0577898017123185 0.0021637050259114 0.000167750366804 0.0102355224712358 0.0165908314289981 +Neuron death 17 76 2.538717014929464 0.0111259776198344 14.20388349514563 73.25242718446601 0.8007457732231772 0.4829929240620625 5.370919943079612 7.537889337352574 0.9625497526284538 0.3667297831171348 0.2142906638899178 0.0036684023597506 0.0186875909530785 0.0870972014124965 0.1205120626428805 +Response to oxygen levels 17 71 2.534996792303564 0.0112448355717058 12.5 62.737864077669904 0.8042614609462893 0.4659445696529398 5.042296826006319 7.106965221607376 0.959407798819026 0.3671515409983293 1.0 0.0126546404622538 0.0101299742854952 0.0185467257856752 0.0060620614154558 +Endothelial cell proliferation 5 19 2.5318640964948536 0.0113457956473663 3.737864077669903 17.388349514563107 0.8369436650143091 0.4126693113525184 2.24564806763238 2.518795403681403 0.8441326938580735 0.2996825893791121 0.0026671483108563 0.0461595615554375 0.1529837701743424 0.0312610879309806 0.143549387276975 +Dna damage response signal transduction by p53 class mediator 3 17 2.528437278697744 0.0114571555578757 3.5776699029126213 15.762135922330096 0.1686914652552439 0.6414479859025992 2.8295058417525207 2.494989795292257 0.7106701222418136 0.278614187097779 1.0 0.2180755491779121 0.3924527927004838 0.3583320648627024 0.2458770605062358 +Vacuolar acidification 5 10 2.5242196917270805 0.0115955438250106 3.4757281553398056 8.922330097087379 1.27407749822917 0.1611429668415415 1.4148632661931722 1.303016071016461 1.4195929612668792 0.2212670077717619 1.0 0.0031646532309382 2.1265295896701374e-05 0.0007750266814789 0.0001445816257764 +Immune effector process 25 84 2.522648269774979 0.0116474836513349 15.24757281553398 71.95145631067962 0.1132149302474773 0.7134571835986485 5.865968077599497 7.248540048217676 0.7436652301031837 0.3039621470392462 1.0 0.0288174339547207 0.030717644159281 0.0170967794167786 0.033458190738529 +Regulation of blood pressure 6 22 2.5109763076607043 0.0120397777158254 5.762135922330097 17.737864077669904 1.3077123393993415 0.1882731913471478 2.2751770017499977 2.3871059987956724 1.372929386780725 0.2480453688154592 0.0608528410554385 0.0025198212347625 0.0022045770387089 0.0026306375243077 0.0066608970268297 +Anatomical structure maturation 4 32 2.509685396042464 0.0120838765105331 6.815533980582524 30.893203883495147 0.3841260505655395 0.5416451005267833 3.09006416754166 4.620895179443306 0.9281404590939007 0.3269797675509184 0.1163932569065848 0.0019746919371654 0.0045581119989154 0.1412576665940389 0.318856138803974 +Plasma membrane organization 11 37 2.4993046597267807 0.0124437281156259 7.099514563106796 28.24514563106796 0.6737258386983643 0.4958528160030953 3.5234718862626195 4.368421626063976 0.8695791931528731 0.3271220115282837 1.0 0.3186897272236745 0.0418077700405269 0.0133560961650828 0.0005068912860658 +Fatty acid transport 5 18 2.4905247243204744 0.0127554620650831 4.405339805825243 16.594660194174757 0.9956425124175664 0.363449355794835 2.458050105556273 1.867782713051167 0.7812672834370499 0.2834143639149277 1.0 0.0151070197534971 0.0553157666334183 0.0153023562212604 0.0120719478590556 +Lymphocyte apoptotic process 2 19 2.489858864102985 0.0127793831652667 2.9514563106796117 15.24757281553398 0.5373359856012997 0.4921541780831517 2.125337852190875 2.356949841506499 0.8748252580005311 0.2965231483725897 0.0433751782957271 0.0158345246348345 0.0068495888428019 0.0756846958642696 0.3217125501336962 +Positive regulation of production of molecular mediator of immune response 10 26 2.4891657351438705 0.0128043260618724 6.055825242718447 22.58009708737864 -0.1854991110015342 0.6574128203892317 3.2626587003090917 2.243846383448695 0.7054080460137688 0.2847062544921292 1.0 0.2543128795765555 0.1174994317391053 0.0166327696461577 0.0099258782765325 +Sphingolipid metabolic process 10 34 2.4890226753042666 0.0128094795648436 12.631067961165048 29.174757281553397 1.3566630100256978 0.1614907042591146 4.986857078326301 3.461093559903884 2.232073980338918 0.2503191978902473 1.0 0.3595675699526711 0.0122290647268822 0.0019103185828395 0.0057738946985792 +Calcium ion import 9 17 2.486381903745848 0.0129049393656388 4.516990291262136 12.686893203883496 1.0417029373125424 0.2391249176108038 2.3196506830054986 1.9148178088324157 1.3383409214307818 0.27915846054651 1.0 0.1604648724397155 0.2983459236646945 0.0116952906397438 7.193538924486766e-06 +Positive regulation of lipid localization 2 14 2.471017209061509 0.0134729335059193 2.378640776699029 11.87378640776699 -0.052441312972462 0.4621434947628018 1.7058807755740677 1.980142250702998 0.9846466073226694 0.2640782192574804 0.0495772435509842 0.0013730155435698 0.0100008174701386 0.1038817567329197 0.4023686447738411 +Positive regulation of protein binding 5 26 2.4648473609074317 0.0137071629924405 5.099514563106796 23.00242718446602 0.3155864476850776 0.5869976520948652 2.6175842559823277 2.8459635752908654 0.8435085117004013 0.3185282020054304 1.0 0.0384617608576108 0.0035346784339561 0.0212699465140733 0.1007899732540167 +Neuron apoptotic process 13 49 2.463366124160621 0.0137639286061099 11.191747572815531 49.65533980582524 0.9007291731588002 0.4299023129629146 4.0102574614548505 4.518854312987721 0.9862249081516458 0.3541854094791909 0.1486399534947442 0.0322247907180468 0.0524430873924757 0.1480406608198908 0.1063137228069698 +Ph reduction 5 14 2.4576307839134186 0.0139856876953876 4.422330097087379 12.509708737864075 1.1966830084586066 0.1930048880851129 1.91475781321527 1.7851607614701208 1.4167744165903868 0.2497649393583847 1.0 0.0075879492488378 0.0001322789716162 0.0042924995678 0.0002995500484788 +Regulation of ph 8 24 2.457297687164824 0.0139986633699913 6.890776699029126 20.859223300970875 1.2151699598837196 0.2373503364294603 2.930458126920059 2.7746402510870145 1.4154672965603718 0.2873526492076106 1.0 0.0247821522094747 0.0014691652083679 0.0362911702166911 0.000803590299411 +Regulation of cellular ph 8 24 2.457297687164824 0.0139986633699913 6.885922330097087 20.844660194174757 1.215766922704761 0.2375185297794358 2.9319293283093293 2.765976649626597 1.4143296516981956 0.2875299337708636 1.0 0.0221752921749746 0.0011750725005838 0.0300192966842153 0.000510790199304 +Biological adhesion 43 200 2.4554229206947578 0.014071892683203 36.79854368932039 169.14320388349515 -0.0786074092810717 0.7268401382457587 13.443000770803348 22.05897605707452 0.7413278367584214 0.3123990966272218 0.1624735090371674 0.210752429016652 0.1929634941672259 0.20058616327514 0.0284125996735413 +Positive regulation of cytokine production involved in immune response 7 13 2.4364098240913408 0.0148338675397914 3.2888349514563107 10.283980582524272 -0.091058672378647 0.5794441673319322 2.2233473412724885 1.6878882306700913 0.8266563832986091 0.2885463482468746 1.0 0.1604648724397155 0.2983459236646945 0.0116952906397438 0.0082637154660588 +Production of molecular mediator of immune response 14 41 2.431134853174392 0.0150516112874883 7.235436893203883 35.79854368932039 0.0432269748974599 0.6788563380616658 4.246118336272457 3.347321464388403 0.6815992129922686 0.2863924690311161 1.0 0.0859067555785777 0.0765304167823503 0.0397562781277324 0.0296486341001944 +Regulation of response to external stimulus 37 150 2.425855382905603 0.0152723547247695 27.32766990291262 129.63349514563106 0.3937649860570471 0.6986677015868525 9.316542933972368 15.399506498758855 0.8616366228871625 0.3591499966721317 1.0 0.0517738906553698 0.0218070024776315 0.017322158222965 0.0197029635332775 +Lymphocyte homeostasis 2 9 2.418372790215374 0.0155900956352201 2.6140776699029127 9.157766990291265 0.5015073935560286 0.4550844260550281 1.7177248086463766 2.3424870328572864 0.9807186663047854 0.3016646201978763 0.0402603687682826 0.0136970422924113 0.00553293278753 0.0630731351339203 0.2812242430558347 +Negative regulation of lymphocyte apoptotic process 2 7 2.4139198329674865 0.0157819343226663 1.4368932038834952 4.827669902912621 0.5394724631500855 0.429843922437068 1.0942914798916792 1.2373285534927012 1.0763953212919928 0.3167022382829639 0.0181972414506333 0.0028214739728005 0.0005152543640852 0.0073447144383531 0.0468003866103798 +Negative regulation of leukocyte apoptotic process 2 7 2.4139198329674865 0.0157819343226663 1.4368932038834952 4.827669902912621 0.5394724631500855 0.429843922437068 1.0942914798916792 1.2373285534927012 1.0763953212919928 0.3167022382829639 0.0245475710798989 0.0051552423978184 0.0012875484046766 0.0172025832638257 0.0986013223955862 +Negative regulation of cell population proliferation 23 112 2.4117007019803194 0.0158783100033093 19.383495145631063 97.08252427184466 0.1581356625225672 0.7238624266901581 7.86528068228601 11.547200956886966 0.6889214696860141 0.3091925248352111 0.3569795676213044 0.0108177965954789 0.0368688781940149 0.0083693305046417 0.0819953181309693 +Membrane invagination 7 17 2.4077704447173094 0.0160502695298723 3.6941747572815538 12.16019417475728 0.0473496567323534 0.6174394728479946 2.548303271138053 2.060626721793156 0.8509677037136445 0.3077347987860288 1.0 0.1683799151698467 0.0528695758908991 0.0023124348467711 0.000479523089417 +Regulation of immune effector process 19 54 2.402644880897961 0.0162769854421838 10.233009708737864 43.83252427184466 0.0746422295703071 0.6669022922564953 4.121819476399015 4.72533046431503 0.7694900850686928 0.3075467655920855 1.0 0.142225435971089 0.1506786761356137 0.0207986115182191 0.0086439283677391 +Developmental maturation 7 44 2.3939764072628167 0.0166668208252562 9.04126213592233 42.12378640776699 0.2951074102250363 0.6104336491102619 3.871823327934924 5.43913517834949 0.8662608425150371 0.3328054790113054 0.1505030705182083 0.0052996216004342 0.0140739987975943 0.1547075519871022 0.1946915422899277 +Appendage development 5 19 2.3843598663612955 0.0171088626488522 3.283980582524272 15.37621359223301 0.1480909574057644 0.5969421392568955 2.39526954512383 3.7053775187314058 0.7995041457403814 0.2918586249779653 0.1259909460907461 0.4449535115530259 0.3307022742616863 0.3508407564167967 0.5645833890237784 +Regulation of b cell activation 6 19 2.3754919673793244 0.0175255738522943 4.223300970873787 16.516990291262136 0.0577495350333673 0.5689697369892935 2.5301369502630555 2.1860552471506893 0.9138021371463246 0.3063589445117784 1.0 0.2578448493622087 0.0219695062893176 0.1942870876140905 0.1911113097282704 +Tetrapyrrole metabolic process 6 24 2.3742587220640834 0.0175842244010386 5.652912621359223 19.283980582524272 1.0342508202848784 0.290677507336007 2.6828141040028877 2.549402305664568 1.2308389507353266 0.2976223887279709 0.0464807950830388 0.0011325878612279 0.0083373177591013 0.0039562767661884 0.0011157102419642 +Leukocyte apoptotic process 4 25 2.368548640274548 0.017858032049121 4.094660194174757 20.116504854368937 0.319607386113788 0.5151581496278227 2.552035287340865 3.1105862803108337 0.939636459151083 0.2990440433897824 0.0659377960942512 0.0353307530420815 0.0029853244711116 0.0177220872628324 0.1911113097282704 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0 6 2.364980427913867 0.0180310238013956 1.7378640776699028 5.475728155339806 0.2504530407094367 0.5306514139754194 1.3596913202559946 0.9040863026311896 0.8846503173967747 0.2971649214887787 1.0 0.0683810764565047 0.1336663515258769 0.3069124011154697 0.5269580067311792 +Phosphatidylglycerol metabolic process 1 11 2.3557287181527964 0.0184864126870061 3.7572815533980584 10.78640776699029 0.7074456860764219 0.3298030384317407 2.521619218643941 1.658461595229837 1.2128783939533223 0.2875854965146425 0.026656035141596 0.0060764540616979 0.0233124310373507 0.1211421538065826 0.345186345277882 +Cell activation 34 149 2.3550154867086595 0.0185219337500999 25.703883495145632 129.35679611650485 0.0692955426080309 0.7387037397563144 8.997285699976919 13.941847930447135 0.6883852192819997 0.3033879823523219 0.0938180254702643 0.0255641349439762 0.0169385417257174 0.196433597234071 0.3350824173960546 +Positive regulation of tumor necrosis factor superfamily cytokine production 3 14 2.351538531452004 0.0186959531620622 3.313106796116505 13.021844660194176 -0.0749323239771777 0.5255818975341178 2.0112603058084755 1.6301195665080102 0.950576324381458 0.3044652530020598 1.0 0.018891152845815 0.0681167311872175 0.0940672040532474 0.1740747384317906 +Embryonic appendage morphogenesis 3 13 2.349087395834446 0.0188194889604869 2.3228155339805827 10.531553398058252 0.2830839749911006 0.5346739883331655 1.9546220638717424 2.634991297965238 0.8859883497178963 0.2947695295685748 0.0850331895047633 0.3219228357858488 0.183361016235644 0.3173461003371735 0.5699850788795923 +Regulation of production of molecular mediator of immune response 12 31 2.344263638293548 0.0190646900143027 5.740291262135922 26.553398058252423 0.0466099122995054 0.6804863109851987 3.4483748687685796 2.5197401443299037 0.6715302996287227 0.280576496857416 1.0 0.2989716991852097 0.1596470307013262 0.0345747530672156 0.0287358226060079 +Regulation of glycoprotein metabolic process 4 13 2.3417412477964192 0.0191940167393103 3.592233009708738 10.70631067961165 0.6804974065630551 0.4353046559123504 2.03935499608955 1.985055569049905 0.9883671343018048 0.3255557758909779 1.0 1.0 0.23510055646516 0.1457934990596532 0.0103633783340074 +Porphyrin containing compound metabolic process 2 19 2.3378024242889417 0.0193974998023258 4.91747572815534 16.531553398058254 1.0269348271542438 0.279733852070357 2.276512713100022 2.089380108414912 1.2578863722796805 0.2914421038569487 0.0371363420154888 0.0005765764868268 0.004381787725469 0.051542815486873 0.0259406914165302 +Lymphocyte activation 26 110 2.3365339468617727 0.019463430487576 19.75242718446602 96.97815533980582 0.2587104991344978 0.7054244518764566 7.147670469313885 9.69771309720366 0.6795078753957892 0.3167596875043957 0.0551172681639793 0.0260921429099365 0.0070391132965947 0.1590770494551575 0.2965749525575333 +Cellular monovalent inorganic cation homeostasis 9 28 2.3310177466166504 0.0197524239233581 8.191747572815533 25.12378640776699 1.1978511848260835 0.2636491484517694 3.558748260132903 2.9783551257949803 1.4212259473978417 0.3021468238591936 1.0 0.0333019544595367 0.0026534702472046 0.0593060830293246 0.0006517545393382 +Positive regulation of intracellular signal transduction 30 160 2.3298711218473103 0.0198129637343913 27.288834951456312 140.873786407767 0.0482146245328526 0.8126630522005927 10.345092716010624 16.77401458431364 0.5243533182921788 0.2608921177741322 1.0 0.2258883064333939 0.2224716836709112 0.4828775893149186 0.134265769499784 +Long chain fatty acid transport 5 14 2.3284023663562565 0.0198907481249217 3.4514563106796117 12.980582524271844 1.1347693444093316 0.300255043373995 1.9890654524939184 1.4909473272084874 0.7833838873177712 0.258106472565451 1.0 0.0086801325315587 0.032784445092202 0.0055331858379351 0.0028128505043211 +Mitochondrial transmembrane transport 13 57 2.3272540997522384 0.0199517451767423 19.070388349514563 50.63834951456311 1.9310146760091371 0.188342667216329 9.760351579527285 3.939196260509299 1.9786128158557912 0.3017981993827387 1.0 0.0006619831437869 0.0012638007556123 3.55842041397339e-05 5.4416082575380834e-05 +Blood vessel endothelial cell migration 4 23 2.322574942578816 0.0202019981207246 4.536407766990291 22.449029126213592 0.7681724367497832 0.3963490094539818 2.4704338498615206 2.406468634828595 1.0319905271466427 0.3120666413936225 0.0024553079724538 0.0427950226871739 0.14309893285135 0.0884683246757208 0.2535379185251815 +Regulation of lysosomal lumen ph 4 7 2.3197375127950703 0.0203550812218067 2.3567961165048543 5.58252427184466 1.1719038900849827 0.159040563248536 1.2351555175791742 1.4280428037740598 1.4707016211600112 0.2132438131163355 1.0 0.0683810764565047 0.0086772133501052 0.0495157384890535 0.0005338561483377 +Cellular response to retinoic acid 1 9 2.3116950789396107 0.0207944927771905 2.558252427184466 8.975728155339805 0.1100234272954624 0.5747491502792234 1.8692724440971944 1.840586969452924 0.8142316796486371 0.2840173217186483 0.0392200518637268 0.1604648724397155 0.0480988323617951 0.224257489169728 0.5434948789645544 +Suppression of viral release by host 3 8 2.309900630846877 0.0208936561431125 1.808252427184466 4.900485436893204 0.1546907670699923 0.5284647645806793 1.5071447493534975 1.2036755027030055 0.9418636473359748 0.3135183162225088 1.0 0.0639684350193291 0.0075668597133861 0.0041470760753771 0.0037486095651754 +Positive regulation of chemokine production 4 9 2.30648786509592 0.0210833874157712 1.703883495145631 7.002427184466019 1.1308330497685224 0.261365768238967 1.2206493839204828 0.948936007151574 0.9251734036107908 0.2478284645013121 1.0 0.0051552423978184 0.0199028792923938 0.0020400745925255 0.0043329575683166 +Cellular response to hydrogen peroxide 5 23 2.3040645119018413 0.0212190224935668 4.106796116504855 18.808252427184467 0.1485412495260605 0.550664878178735 3.033510643216732 2.653927270235187 0.922662597256843 0.298572204089493 0.0618718407336946 0.0313211948286675 0.1082339466870539 0.1700362094205073 0.0659378334998033 +Membrane protein proteolysis 9 14 2.304063453212541 0.0212190819141178 4.138349514563107 11.781553398058252 1.0093176076341577 0.3069750059979975 2.078037067185485 1.3902746514167437 1.0484204695389652 0.2877212872591311 1.0 1.0 1.0 0.0025916473916576 0.0001003888941435 +Transforming growth factor beta receptor signaling pathway 6 31 2.3006298174933937 0.021412564149345 6.740291262135922 24.87864077669903 -0.0956469866681699 0.6387114391471552 3.777556089888507 3.581889464108928 0.7561955554325939 0.2952697884954297 1.0 0.4260868249492235 0.3061707382604345 0.0230184986659368 0.3426883126439601 +Protein processing 18 51 2.284054095375942 0.0223683519418589 12.08252427184466 45.980582524271846 0.9011703887478908 0.3916089016010577 4.43430858840224 4.931040148104543 1.176660792763282 0.3507158233798557 1.0 0.139002656989977 0.0433617035599321 0.0511334512109197 0.0001331062361034 +Monovalent inorganic cation homeostasis 9 32 2.282382165176677 0.0224667873589194 9.014563106796116 27.87378640776699 1.1567920478867002 0.2845186374336156 4.051822262152646 3.607380814764068 1.4117439861533438 0.3149022278800241 1.0 0.0461595615554375 0.005075346294965 0.0994768290011166 0.0026677547140881 +Regulation of synapse structure or activity 10 34 2.281464425611921 0.0225209794774776 6.665048543689321 33.640776699029125 0.4177416009353497 0.6162292560215563 4.025337439581666 3.7073905955276114 0.8008691737125054 0.3301048213868146 1.0 0.1123544518992548 0.1101605797563029 0.5679451642648087 0.073220440303708 +Apoptotic cell clearance 2 10 2.279988966415004 0.0226083428781016 1.4150485436893203 8.16747572815534 0.7343377868729896 0.4133364508748849 1.6160802235364573 1.40166698151907 0.89060803593971 0.2988103853625464 0.0213770889355645 0.0901405579438761 0.1741653971767485 0.0116756742779249 0.0705348016344186 +Response to transforming growth factor beta 8 39 2.278290507457164 0.0227092748561041 8.410194174757281 32.536407766990294 -0.094101059672419 0.6394779055878194 4.225924723432897 4.710671082480533 0.7756039910569711 0.2958728495226654 1.0 0.5122009359255594 0.4225214891482289 0.072957415156093 0.31394996595046 +Lipid localization 16 94 2.276458301057388 0.0228185936520393 20.1504854368932 74.27912621359224 1.3966421040883936 0.3001252105784707 7.306180038477171 9.39465098860316 1.572418240819249 0.3627304234720817 0.0226138554576466 0.0036684023597506 0.0050429859987598 0.0182014765947577 0.0222580391170248 +Regulation of intrinsic apoptotic signaling pathway by p53 class mediator 2 11 2.2726199531806106 0.0230490921628081 2.75 9.228155339805824 0.0603631208299846 0.6086096975000811 1.850773913169813 1.225293107452464 0.7651140384610741 0.2787062873314581 1.0 0.1114021565620111 0.2127898194125335 0.4573561220916043 0.1194171261960574 +Membrane protein ectodomain proteolysis 6 11 2.271691967371752 0.0231051216933753 3.2815533980582523 9.42233009708738 0.914660566901433 0.3175120830558543 1.6482852268027584 1.2623319489295757 0.9882621955102872 0.2679281534911034 1.0 1.0 1.0 0.0062346640440273 0.0005860509424053 +Leukocyte homeostasis 3 14 2.267324537810267 0.0233704075651295 3.4029126213592233 12.177184466019416 0.5028432712633871 0.4794963594230453 1.9872875748080177 2.4917658251002113 0.9479568975066928 0.3126900449378977 0.0547176831179111 0.0247821522094747 0.0131741361742053 0.0362911702166911 0.1072426750643267 +Regulation of leukocyte proliferation 4 29 2.262282105593108 0.0236799792890336 5.752427184466019 23.393203883495147 0.3932260927985178 0.5806940436166351 2.797687833832017 3.7032853987829895 0.8370636232955005 0.3221548844899082 0.100837504828815 0.0108939889612075 0.0023748989920206 0.0880352084429092 0.1039108351956171 +Adaptive immune response 15 49 2.2616840542464733 0.0237169306173579 10.065533980582524 42.351941747572816 0.273358349465438 0.6058955707869721 3.753713560137982 4.529827909513841 0.8726173227089915 0.3277958822259462 1.0 0.5460422758388164 0.209850660837357 0.1069268644827387 0.1850900682022142 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 11 37 2.258772732604993 0.0238975255049214 7.757281553398058 32.31310679611651 0.1415333879820327 0.6037463529133537 3.504410589660101 3.044416034085123 0.8740255675036868 0.3157880382593289 1.0 0.4342482165093504 0.1061761164696546 0.0701527069806367 0.2290551422363448 +Myotube differentiation 6 17 2.2585849424932176 0.0239092153265887 3.917475728155339 15.429611650485436 0.7362493461217297 0.4654023872843359 2.2583148277114424 1.8108081242298664 0.8490361901889097 0.3242501735929494 1.0 1.0 0.1082339466870539 0.1700362094205073 0.0236488585480569 +Protein homooligomerization 6 48 2.250673976452344 0.0244061941805455 8.800970873786408 41.21601941747573 -0.6243653651892556 0.477906008154873 3.9657758002918913 3.425976677357527 0.9490438575053944 0.324832142020925 0.0054379227028889 0.0014590049028022 0.0032054420789335 0.013435076878633 0.0129452724374584 +Carbohydrate derivative transport 6 23 2.2483067072085428 0.0245566393279113 7.924757281553398 17.024271844660195 1.3665639952580566 0.1869571280171947 4.210097511648942 2.624454303682939 1.5541767319140831 0.2467993156006303 0.048546111259079 0.1955113655682517 0.0094265313681113 0.0989248704147511 0.0712683628665124 +Neuron maturation 1 5 2.247220410967836 0.0246259443645704 1.6966019417475728 5.737864077669903 0.3884050692002241 0.3270287101850628 1.1310653568868725 1.188220216330287 1.2760249805885358 0.2674215567147113 1.0 0.0060764540616979 0.0233124310373507 0.1211421538065826 0.345186345277882 +Positive regulation of adaptive immune response 7 18 2.246702728013067 0.0246590317976038 4.638349514563107 16.04126213592233 0.0444780909393623 0.5363245981420569 2.2998069134178674 2.0207050483556 0.953162271864993 0.3079428375592325 1.0 1.0 0.0932703984994284 0.0408612650970917 0.1208874805839759 +Transmembrane transport 67 254 2.24170455006228 0.0249804736221912 67.45631067961165 211.1359223300971 1.8122664376950308 0.3598356673827246 27.267027885156203 22.354947126810902 2.251277763144546 0.4188333713481413 0.5139847601102487 3.230851893426223e-05 3.2501646406979924e-05 0.0004162239832817 1.5393359351871742e-05 +Vitamin transport 7 10 2.237163863371362 0.025275632224436 3.587378640776699 7.597087378640777 1.658661901456128 0.1256251915839625 1.8073839707699664 1.6422194495621811 1.0713624000848283 0.1994200282768667 0.0256023215689562 0.1071891284628969 0.0215793786244467 0.0193169154759243 0.0052582215982291 +Iron ion homeostasis 2 17 2.235842539012846 0.0253620873473032 4.468446601941747 17.140776699029125 1.0306963602610326 0.26770320823289 2.1032740346004313 1.762496954108992 1.1437451534606062 0.2692749918411525 1.0 0.001740287381965 0.012498849387857 0.124643595331372 0.2352128770122224 +Cell activation involved in immune response 14 42 2.230780080250621 0.0256957000570057 7.424757281553398 37.133495145631066 0.2013804059718359 0.6332706700932498 3.985004499798946 3.76547221312819 0.8111784803604789 0.3140247982994989 1.0 0.1247184766082311 0.0352488503773986 0.0378423114252983 0.1013003333387519 +Positive regulation of immune response 22 82 2.224550059881972 0.0261114583664701 17.12378640776699 74.37864077669903 -0.0501134629817833 0.7334386081921995 6.2846489836411905 7.17616944206656 0.6338613305150654 0.282656931792322 0.2246308581442339 0.3002976743483729 0.0711103723428942 0.1111617640619781 0.1635785283526323 +Chemokine production 3 11 2.22042954665085 0.026389623231261 1.8810679611650485 8.337378640776699 0.9152793985046536 0.327029475914965 1.2820382835273771 1.4780796128991345 0.9350060766690576 0.2657366976150246 1.0 0.0098384095742339 0.0369282917904302 0.0069928111010265 0.0181161163925661 +Regulation of immune response 34 136 2.2164547358380404 0.0266603745870832 25.00242718446602 119.80339805825244 0.248728055937711 0.7234553499352745 8.655908467072013 12.491655004997526 0.7490545850270482 0.335364410227988 0.3497176052376853 0.2792952916626935 0.0324608952305598 0.0514786949311137 0.0978526114236303 +Positive regulation of cell junction assembly 4 13 2.2134137825584936 0.0268691313144462 3.063106796116505 10.70631067961165 0.202527500453485 0.5734869063143083 2.267520363799425 1.8098058096179055 0.8320845471156263 0.2984713165760313 1.0 1.0 0.3686542667111886 0.6911948368646196 0.0824033164968481 +Regulation of adaptive immune response 9 24 2.206549457444387 0.0273455513522897 5.449029126213592 21.189320388349515 0.0253934788905023 0.5888818376469294 2.588215269390292 2.394995292427391 0.8567740173979026 0.3072913066668554 1.0 1.0 0.1731294929006003 0.1232731888960198 0.1857409053471585 +Regulation of nervous system process 3 12 2.2006181324083114 0.027763068844945 2.6941747572815533 11.186893203883496 0.709685710886722 0.4267375683332639 1.6891041598029932 2.2483053074671338 0.9287991925104498 0.3050882814355576 1.0 0.0247821522094747 0.0874698992517949 0.3583320648627024 0.2458770605062358 +Transition metal ion homeostasis 3 25 2.192126344284802 0.028370385000449 6.640776699029126 24.57281553398058 0.9239194315613378 0.3015424973151205 2.934079531592402 2.8081087224394015 1.2471169312381896 0.2974369333820005 1.0 0.0005260552703788 0.0070126150189725 0.1274569302589828 0.193206221510934 +Regulation of anion transport 2 14 2.1898648442337887 0.0285340402734559 3.657766990291262 11.50242718446602 0.7713855446015195 0.3761489496061844 2.0089273726107977 1.6987985280405251 0.9512307489218268 0.2850669663772418 1.0 0.0104419310742173 0.0037031463805551 0.0444854600227105 0.0205229364106292 +Enzyme linked receptor protein signaling pathway 25 131 2.1859383657705447 0.0288201148692444 25.24271844660194 117.68932038834951 0.1053848292396163 0.7149684279491084 9.284046259048107 15.168490031291515 0.7848849412953816 0.3313693252810506 1.0 0.4473167530581073 0.3760901247226935 0.2762600174366754 0.4757778692061605 +Protein targeting to lysosome 3 14 2.18311918647008 0.0290270339914753 2.861650485436894 11.133495145631068 0.4665494631806399 0.3733123029661771 1.8767316131355816 1.7651272451933906 1.2080503341010538 0.3026029882111192 1.0 0.0944323477659319 0.1820374447866984 0.0901924811619011 0.0171177319456962 +Positive regulation of mapk cascade 10 53 2.171793403534969 0.0298712494683877 10.529126213592232 45.83495145631068 -0.1934904160278876 0.6167608389842509 5.511385057852045 7.00568020214532 0.7988580356266328 0.3026624883715406 1.0 0.0758522953055849 0.13970724106502 0.5752902019482493 0.4448089578730225 +Microtubule organizing center organization 13 51 2.1665569107568463 0.0302686559681442 10.985436893203884 40.730582524271846 0.0531780861213523 0.6579413251048066 5.115632006755549 6.500017673649269 0.8024863779803786 0.3148854550379723 1.0 0.1262869582908406 0.354998822540133 0.828965326651507 0.0256408760505761 +Negative regulation of neuron projection development 6 20 2.1636223423485204 0.0304933453889164 4.944174757281553 19.932038834951456 0.8070712719008988 0.4165241941447024 2.3357271686464363 2.7475042016888107 0.8484003015222881 0.3001902418041021 1.0 0.3186897272236745 0.5403792944088247 0.1316996895499912 0.0984900841438662 +Regulation of erad pathway 0 8 2.163614165336127 0.0304939734697053 2.0024271844660193 6.449029126213592 0.6710358947065599 0.4273068846088207 1.332015748193602 0.952678405750194 0.8726601892197801 0.2893902603244691 0.0192582327414155 0.0814971443263516 0.1581956798045988 0.3559534457378639 0.5927878722461318 +Regulation of toll like receptor signaling pathway 3 13 2.160307929982112 0.0307488394910986 2.587378640776699 9.50485436893204 0.9772136844316576 0.3297728067967737 1.666236944633112 1.8466647258935645 0.9012634534298872 0.2761306672489575 1.0 0.1801156574188796 0.0073262411490521 0.0801176308941427 0.1458719137718038 +Response to food 2 8 2.157138370774821 0.0309948846680723 1.720873786407767 5.783980582524272 1.3281223897944048 0.1823213242558801 0.9790282548915298 0.8299231919143666 1.0823564620426191 0.211054619984942 1.0 0.0016377422378922 0.0002227826640135 0.0033170374819039 0.0227185425065092 +Fatty acid transmembrane transport 4 9 2.1480866274019803 0.0317068743523776 2.3519417475728157 6.720873786407767 1.487456141723218 0.1763040127694548 1.5547987465385102 1.1092073674791965 0.7935702169981724 0.2103298472796338 1.0 0.0550816697898294 0.1084298440104649 0.0025975272437437 0.0001590313802548 +Positive regulation of b cell activation 2 14 2.1462359708112646 0.0318541570877541 3.092233009708738 11.186893203883496 0.1859276114166038 0.5045227221699764 1.8118375224733587 1.264344128777142 1.0073127631140006 0.3002532228225043 1.0 0.1723099894081314 0.0063919517402272 0.0713646261968556 0.0432084674189714 +Pinocytosis 3 8 2.14378824535044 0.0320498576139933 1.8713592233009708 7.33252427184466 0.5840579949486326 0.3745201042297812 1.4960968950914608 1.2320991783672317 1.0871891924456092 0.2933375341256155 1.0 0.0814971443263516 0.0124120710913681 0.0688460117016781 0.0098193480789534 +Cytokine production involved in immune response 8 15 2.143723210973404 0.0320550712648184 2.441747572815534 11.356796116504857 0.4093967072187203 0.5138902009456215 1.857549501324998 1.803819417905269 0.799103762168713 0.2723815630799965 1.0 0.1839914155878272 0.3376050929703735 0.0195417527514502 0.0169717228577044 +Lysosomal lumen acidification 3 5 2.142299105755661 0.0321694207612373 1.9077669902912624 4.094660194174757 1.0430284513288333 0.1731957374320673 1.0102570393282595 1.1504623937719378 1.495459416196642 0.2154807950267566 1.0 0.0506073598520519 0.0046590638338273 0.0276231155809849 0.00138858926748 +Fibroblast proliferation 3 14 2.1407580046875534 0.0322935581771728 3.366504854368932 14.82766990291262 0.5124593862752868 0.5850553003140551 1.9704477874295845 2.154676874783138 0.6165697354941142 0.2839756513851624 1.0 0.2180755491779121 0.3924527927004838 0.1300529274831162 0.2458770605062358 +Glycolipid biosynthetic process 5 12 2.1389517250218995 0.0324395782778628 3.3009708737864076 8.701456310679612 0.8778541677747596 0.2891249509557468 2.0940737065519093 2.1465026455410077 1.206628042966233 0.2848826766737565 1.0 1.0 0.2915824887707032 0.5855309260576435 0.0289613396123399 +Negative regulation of dna damage response signal transduction by p53 class mediator 0 5 2.1384215224720227 0.0324825472189769 1.4150485436893203 3.9927184466019416 0.2121791049915313 0.4958230262563545 1.1299397473294612 0.6843928556917136 1.0555796685180847 0.3098183755596199 1.0 0.0461123069087121 0.0912026913027489 0.2167775624926856 0.3928150466925536 +Regulation of b cell proliferation 3 8 2.136965308901399 0.0326008133336213 1.7888349514563109 6.067961165048544 0.296043135362402 0.4569644069441661 1.2213996435499042 1.8129102062616271 1.0614819725849571 0.3010373616882123 1.0 0.1114021565620111 0.0233124310373507 0.1211421538065826 0.031065887399213 +Cell death in response to hydrogen peroxide 0 10 2.1279250240456653 0.0333433004333119 1.7233009708737863 7.783980582524272 0.1094685070661782 0.4314424507239962 1.726757097702244 1.184214818977975 1.075218120694276 0.2698396762332269 0.0203181815952763 0.0858288536093336 0.1662183776826317 0.3715199079432311 0.2355870590704462 +Lipopolysaccharide mediated signaling pathway 1 9 2.124458186213227 0.033631848941064 1.8737864077669903 8.281553398058252 0.8878970764300863 0.35030444949346 1.2399468486141116 1.678924041304143 0.8123823005829252 0.2523157110268533 0.0319090813612602 0.0086801325315587 0.032784445092202 0.1627514901813832 0.4325786085596129 +Regulation of cell activation 23 77 2.123586785402633 0.033704711509473 13.849514563106796 65.59223300970874 0.0117954500841862 0.6466994765328734 5.255295503804918 8.314435794837985 0.810235540435219 0.3149538466828337 0.2499423868015819 0.1262288614573997 0.0125595805517448 0.053902604248962 0.0903745086475338 +I kappab kinase nf kappab signaling 25 58 2.119760542139975 0.0340262444331689 10.145631067961164 49.810679611650485 0.360044073400616 0.6099848557681691 4.404119358078279 7.130073225312779 0.7921548119294252 0.3279566448560211 1.0 0.5856228687134835 0.5283492334992209 0.4628088882570518 0.0670308386917159 +Appendage morphogenesis 3 16 2.111498577700277 0.0347294800394806 2.733009708737864 12.356796116504857 0.1736162467757523 0.5679910710115588 2.1781299697112395 2.7670701317045303 0.8540375906091052 0.2978148567402963 0.0998570540494651 0.3686542667077518 0.235580241074313 0.4161207629557325 0.7012216157200033 +Positive regulation of erad pathway 0 5 2.109258575755657 0.0349222683044216 1.5024271844660195 3.8737864077669903 0.9790138935407412 0.3204829663432698 0.9914654898247502 0.7718293947321084 1.0549703131728962 0.2978461088577541 0.0139428334678447 0.0595353304203936 0.1169218221283287 0.2721697661507766 0.4772731985221821 +Phosphatidylethanolamine metabolic process 2 5 2.106935008040772 0.0351232135521724 1.4174757281553398 3.54126213592233 1.2136417130163286 0.2301275972070245 1.0265813928797825 1.052388111444633 1.16214154732605 0.2536389297154525 1.0 0.0595353304203936 0.0065261066260236 0.0033170374819039 0.0227185425065092 +Endocrine process 3 7 2.1056889120484428 0.03523138360694 1.2548543689320388 4.796116504854369 0.5618420388608887 0.420743873234336 1.155653359589049 1.5445439412417563 1.012934098296112 0.2874992399751413 1.0 0.1403531442218371 0.0369282917904302 0.1800390494619342 0.0678374957909117 +Regulation of leukocyte mediated immunity 16 37 2.105663614988793 0.0352335825142366 7.247572815533981 30.390776699029125 0.1116130068646695 0.6358782484063592 3.3590724754287953 3.498295337807405 0.8071171599029437 0.3154401916393654 1.0 1.0 0.6136255237111328 0.0909960920222553 0.0084879625052324 +Actin filament based movement 8 25 2.1052235208755485 0.0352718557544853 7.128640776699029 26.031553398058257 -0.1292527264707881 0.6205415113005578 3.744958435883181 3.564451579511584 0.8202183533575245 0.3130986383041553 1.0 0.2889042268874887 0.4987612630939496 0.0296820907724347 0.0078843517944469 +Mitochondrial calcium ion transmembrane transport 4 11 2.105096865573401 0.0352828770369186 3.4684466019417477 9.04126213592233 0.7792467211325117 0.2463779000555085 2.196969341156949 1.2010296388602075 1.3738174116662032 0.263849842646199 1.0 0.0727733471903131 0.1419203898220533 0.0557098434243155 0.000745702459351 +Lipid export from cell 1 5 2.1025927643939912 0.0355013829722739 0.970873786407767 2.8932038834951457 0.2910367285044455 0.4715568938765356 0.9238617838836146 1.0231554215679783 1.2098563714199235 0.3249767428136129 1.0 0.0016377422378922 0.0065261066260236 0.0379575415698398 0.129364196063302 +Glycerolipid biosynthetic process 17 52 2.0996397342354585 0.0357605446838935 13.466019417475728 44.71844660194175 0.9430872689732808 0.3767257192898063 6.88753698417372 8.249645447783736 1.3199493331746477 0.3584243730449019 0.0155143492626458 0.0531834981275408 0.0938118896710847 0.0717995711225624 0.1031235203278423 +Negative regulation of cell aging 0 5 2.099527887771691 0.035770392105263 1.4150485436893203 4.436893203883495 0.4449080488727195 0.4593397992109042 1.033453418648996 1.1399191157868775 0.9851582751260632 0.2986294132747129 1.0 0.0771453392642774 0.1500965904253892 0.3400030327298383 0.5719289219770226 +Regulation of signal transduction by p53 class mediator 6 39 2.091322873606232 0.0364991307281921 9.771844660194176 34.45388349514563 -0.1167478125696639 0.6600143110406123 5.754389080050758 3.5444897021380304 0.7241970013652401 0.2980754757248046 1.0 0.3378643758427397 0.5662053531298222 0.6247937785201403 0.2483311702656204 +Viral transcription 5 20 2.0897139676701983 0.0366435015385224 5.466019417475728 15.49514563106796 -0.4213656629457412 0.5309907893364965 3.17473501372791 2.3291057761844285 0.8793019302954951 0.3128432296751765 1.0 0.1839914155878272 0.0078220928632966 0.0195417527514502 0.0169717228577044 +Response to estradiol 2 17 2.089514176791383 0.0366614631427497 4.480582524271845 15.609223300970871 -0.1183336658454337 0.5504992412244947 2.9241398453943264 2.3974526081633196 0.8881612224001193 0.295018926126729 0.0709977095462976 0.0406061543885706 0.1365892396200844 0.2256891642594976 0.6495651864601311 +Rho protein signal transduction 10 26 2.088787810423973 0.036726828166484 5.87378640776699 22.861650485436893 -0.1017182812857977 0.6596490805056876 3.4059616826242443 3.7588452567573647 0.7367263185096855 0.2876161119801693 1.0 1.0 0.5703677906367757 0.3571368988977866 0.0034737383152492 +Transition metal ion transport 6 18 2.087851854644402 0.0368112002969964 4.70873786407767 14.08980582524272 0.8861898222657586 0.2678437025860737 2.4756329698054333 2.718007722894407 1.3738160036140448 0.271065502827487 1.0 0.2436179272361805 0.4319828126458854 0.053649406266927 0.0236488585480569 +Neutral lipid biosynthetic process 2 8 2.087016163105662 0.0368866735211625 2.1067961165048543 6.288834951456311 1.1186547336258812 0.1821371148552785 1.2515048910859687 1.3298556757746482 1.2887117600293918 0.213034599641239 0.000366007882586 0.0002645755687248 0.0020687914080252 0.0264830942684438 0.14168603717257 +Positive regulation of leukocyte proliferation 3 18 2.0859912558285494 0.036979415141946 3.861650485436894 14.71359223300971 0.6007881424807215 0.4761380762722816 1.9750347653754128 2.1890082226375087 0.9342511129724644 0.3127219346815347 0.0608528410554385 0.0303491574999332 0.0022045770387089 0.0509365284789281 0.0217195139585283 +Protein complex oligomerization 16 69 2.085961470347085 0.0369821133315455 11.3252427184466 60.27427184466019 -0.5547172093021401 0.5543746590331745 5.379396480506509 4.8994767110993935 0.7840111687827833 0.3290740571640736 0.0109778929755267 0.0054252319048293 0.0144490925895381 0.072957415156093 0.0066706161492779 +Regulation of response to extracellular stimulus 2 6 2.084296562871574 0.0371331998067947 1.0364077669902914 4.466019417475728 1.2416795343104177 0.2058666180593168 0.8221064046230258 0.7766686887277909 1.0462594039989206 0.2178110962907249 1.0 0.0506073598520519 0.0001303190068882 0.001983278822638 0.0140894483762481 +Protein kinase a signaling 1 9 2.081828854078434 0.0373581051812785 2.266990291262136 7.293689320388349 -0.081456555052811 0.491906957237044 1.475225067542489 1.0944072211083502 0.9560488685138026 0.2840804811951539 1.0 0.0035263772514821 0.0137871179019738 0.0757571260003459 0.2355870590704462 +Pigment biosynthetic process 3 27 2.0744189755106133 0.0380404165236494 6.191747572815534 23.20631067961165 0.1176426516349437 0.5124018007570521 3.0504861707649304 2.789310208180288 0.9995589703296716 0.3059733010449426 0.048546111259079 0.019691222561341 0.0009249345366774 0.0244406528674846 0.0230912453221162 +Regulation of viral transcription 3 8 2.0743408000183177 0.0380476711464221 2.058252427184466 5.33252427184466 -0.2370554914447475 0.4868147003845069 1.4834049177054625 1.3433079141892594 0.9701248108398718 0.288418377602304 1.0 0.0727733471903131 0.0098557770733155 0.0061570039439817 0.00630824692371 +Cell morphogenesis involved in differentiation 23 135 2.073755719630438 0.0381020034986803 30.27912621359223 122.126213592233 -0.1867286336625038 0.641278511812741 12.483085690754145 13.9865952550349 0.8140610053379778 0.3158474092010998 1.0 0.3730089430740907 0.1513168217498986 0.5652024266782006 0.4033410701477223 +Vascular transport 6 16 2.0727593200449665 0.0381946840621594 4.774271844660194 13.094660194174756 0.7274519419599351 0.3186647470404632 2.3913310677559982 2.1617303908189505 1.2183781465172474 0.2807075669512824 1.0 0.2106238865638343 0.0118439766153993 0.03203241935523 0.0100459976774882 +Liposaccharide metabolic process 8 22 2.06951073308248 0.038498185195503 7.393203883495145 16.839805825242717 0.7162233803449398 0.1804705798886219 2.8837934205508033 2.921890590438037 1.8930166841377585 0.2403675114219934 1.0 1.0 0.4264955437255276 0.0509365284789281 0.0017963005545976 +Neuron development 42 209 2.067698340445878 0.0386683980742157 34.62135922330097 181.34708737864077 0.2741713926873628 0.7656699386252992 12.599789260723686 22.778234719870852 0.7085731328386405 0.3174955318913259 1.0 0.211603828287165 0.1091184893920115 0.0370198607036634 0.0290344120153214 +Intrinsic apoptotic signaling pathway in response to dna damage 3 27 2.0674713777912914 0.0386897585132146 5.191747572815534 23.4004854368932 0.4729571891933678 0.5742196556826167 2.43550394585209 2.759326595293978 0.7661559213706911 0.3096443051481624 0.0780397298573443 0.0484553320209439 0.0344500399399848 0.1071524979756758 0.1570895071582956 +Iron ion transport 4 11 2.0654691838584847 0.0388786283923086 2.8762135922330097 9.3252427184466 0.6984692822717036 0.3339124009240178 1.7603279794274296 1.4434464182805606 1.1549328537786283 0.2828654848729625 1.0 0.1444128696349771 0.2709026461704186 0.0444854600227105 0.0205229364106292 +Regulation of endothelial cell migration 6 31 2.06499449174638 0.0389235214791459 5.495145631067961 27.978155339805824 0.5955926179251096 0.4502618340992453 2.841693008322481 3.167187428757454 1.0132828172462562 0.3207559953771818 0.0052379230014411 0.0845006677590773 0.2567478928672068 0.1033455447275472 0.2348894408959311 +Regulation of t cell apoptotic process 1 5 2.062248428026923 0.0391840902174056 1.1868932038834952 3.8932038834951457 0.4503832314353733 0.423725835599417 0.9611497252872896 1.2398138081259902 1.1590426056493326 0.321330197772498 0.0150080037348002 0.0639684350193291 0.0075668597133861 0.0435926191526008 0.1462762019757018 +Chemical homeostasis 32 204 2.0608228514790614 0.0393199435587536 43.762135922330096 177.7597087378641 0.7082111793088889 0.511106347874914 13.668464281922288 17.87763227716401 1.3204137511810292 0.4179418895476048 0.0193412084081696 4.235127052106164e-05 0.0002341849922623 0.0493820297218256 0.0138606183686891 +Epithelial cell proliferation 10 53 2.059223852119819 0.0394727992374981 8.395631067961165 43.269417475728154 0.2446678735146439 0.6859066232639723 4.286044223662435 5.981990499848451 0.6158202975211522 0.2863197731416702 0.0224223949991747 0.2775133964310745 0.622987427801012 0.1628263896511071 0.3838488894334729 +Positive regulation of interleukin 1 production 0 7 2.05888091341078 0.0395056479334172 2.075242718446602 7.565533980582524 -0.0360261344876269 0.5208225219870025 1.4850937956453978 1.245604487832095 0.9358677711957404 0.2968726813360106 1.0 0.0901405579438761 0.1741653971767485 0.3867116248199588 0.631511633602643 +Embryonic digit morphogenesis 2 7 2.054635461481489 0.039914227840879 1.4684466019417477 6.54126213592233 0.5989020645284063 0.4429704011231127 1.569266266788618 1.559731853735315 0.934963282113679 0.3039103680308826 1.0 1.0 0.3376050929703735 0.2781824052676386 0.3487517012854798 +Peptidyl tyrosine modification 11 44 2.054193924361833 0.039956926217489 8.70388349514563 37.73543689320388 -0.0239454267802142 0.6861916771215885 4.618418641018608 5.785435895284358 0.6551498843976254 0.2777474877708394 1.0 0.2267486508979282 0.545647232006766 0.8441742661356123 0.4521828841045822 +Regulation of cellular response to transforming growth factor beta stimulus 3 18 2.0507965657302525 0.040286762151962 3.917475728155339 14.519417475728156 0.0747268719946895 0.6467964042170758 2.5548327395508266 2.189363442196086 0.7242791632240214 0.2849042613587436 1.0 1.0 0.5269013915883425 0.1191496891129861 0.5300397282768031 +Negative regulation of immune system process 6 54 2.050266667526446 0.0403384154294494 10.262135922330096 46.91019417475728 0.2444799455656694 0.6277319776406994 4.757132947946456 7.065174604728879 0.8023664740567815 0.321929768279026 0.1716641165114558 0.0087148422915659 0.0244714513307757 0.1252553478047149 0.3334719976026817 +Axon development 17 86 2.04833466558771 0.0405272185066414 15.014563106796116 75.88349514563107 0.4221802741874887 0.6742105443551618 6.65661081388802 8.797672872875632 0.8036898770047755 0.340363217999487 1.0 0.158963117865429 0.1466889096660684 0.0977625911169456 0.1830600391635985 +Cellular response to lipid 15 108 2.047375515706296 0.0406212284808815 18.29368932038835 97.623786407767 0.1587026040111258 0.7518209613158593 7.383309633639688 11.475034836464232 0.5858518561813145 0.2910053581368524 0.0422807275353216 0.057339521218393 0.1727022279579139 0.1300126518172957 0.3398657698015557 +Positive regulation of leukocyte mediated immunity 10 25 2.045596586034576 0.0407960776381808 6.713592233009709 22.83252427184466 -0.2345848852110683 0.5782708579808408 2.8812264292552054 2.077061599998318 0.8958800443287277 0.3178816544993799 1.0 1.0 0.453417077782931 0.1942870876140905 0.0325410063420203 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 3 13 2.037602869067985 0.0415896648895472 3.191747572815534 10.177184466019416 0.3284430151273287 0.5593326661897914 2.095911381429279 1.3293416996099243 0.8418807623245839 0.3022341175821764 1.0 0.1280604643503683 0.2423974925429197 0.154226710893935 0.0501437556032915 +Endothelial cell migration 7 39 2.036237522158512 0.0417265101458996 6.412621359223301 35.5752427184466 0.4082848327362888 0.5352947559852537 3.4640505952618645 3.829708687407978 0.952730213605329 0.3344080805283456 0.008475260214376 0.1278602816552163 0.3584462452886956 0.2139129712520399 0.3130111235472884 +Monocarboxylic acid transport 2 8 2.0358140334739896 0.0417690327153843 2.470873786407767 8.169902912621358 0.4625507315789194 0.4811606769664326 1.4867133927645466 1.500895198986602 0.9205510606636372 0.3061126645026174 1.0 0.0075879492488378 0.0288389511657702 0.0291459656321865 0.1533018949933901 +Regulation of b cell apoptotic process 1 5 2.0335893661100077 0.0419930148909659 1.2888349514563109 4.143203883495145 0.4712803824401109 0.4838259091452473 1.0979113453615192 1.1000341685710282 1.0371325316664826 0.3279009485506359 1.0 0.0595353304203936 0.0065261066260236 0.0379575415698398 0.129364196063302 +Negative regulation of b cell apoptotic process 1 5 2.0335893661100077 0.0419930148909659 1.0121359223300972 3.395631067961165 0.4350946296559548 0.4853099477083538 0.9176522920463588 0.8397181333642862 1.1185142681133764 0.3411168377951629 1.0 0.04159641685533 0.003087611696091 0.0186627473263165 0.0677640175569944 +Regulation of mitochondrial gene expression 4 13 2.0315672371122635 0.0421974862883121 2.594660194174758 11.4247572815534 0.8803116051858394 0.3443222138925089 2.2226265034531534 1.9350293365530056 0.991093358800792 0.2980671372776958 1.0 0.1197698958477507 0.2277340705622599 0.1374615323876937 0.14168603717257 +Regulation of long term synaptic potentiation 3 7 2.031097747043738 0.0422450799680833 2.191747572815534 6.026699029126213 0.6105178624452509 0.3860292464291884 1.2788913032023987 1.4948993461258857 1.1199694698848182 0.3107967468650517 1.0 0.1071891284628969 0.2052107238795277 0.4439075633632242 0.3271248077551284 +Regulation of lipid localization 3 29 2.0273904700666407 0.0426224957782699 4.978155339805825 22.567961165048544 0.1717129002526148 0.4994483702351445 2.509594887654458 3.4172240364068465 0.9420644920260158 0.2891754608342733 0.0810428554278816 0.0058176934433743 0.0380370787536166 0.1191496891129861 0.3298273388868034 +Positive regulation of lipid transport 1 9 2.026122590629447 0.0427522236404245 2.1699029126213594 7.0 0.0691898390202085 0.5172890321450091 1.660584465564179 1.8341422163787937 0.9343638939756568 0.2944184844578439 1.0 0.0110614955842043 0.0412617301526311 0.1975866021584996 0.4978168612908779 +Phosphatidylcholine metabolic process 3 15 2.02377226519758 0.0429935891440766 3.75 12.592233009708735 0.9144963280277142 0.2812959412325629 1.879404212556404 2.4412987678409657 1.1545250012369797 0.2602001877022786 0.0412996615361356 0.0143944751365022 0.0059531349747588 0.0140312853386763 0.0106880220145335 +Synapse organization 21 71 2.01955824458087 0.0434292300165473 15.138349514563108 65.40533980582525 -0.0195426896139076 0.6809714664793302 6.570586502332626 8.060949294302048 0.7450742452311702 0.3050655104564015 1.0 0.3072922687180656 0.3930062738706685 0.5109050315564581 0.1795217751811954 +Negative regulation of signal transduction by p53 class mediator 2 9 2.0194857414294924 0.0434367578263459 2.1262135922330097 6.490291262135922 0.0025135391117914 0.5277846023571443 1.4626721898500985 1.409882909350627 0.9389842991964372 0.2948801347666068 1.0 0.1114021565620111 0.2127898194125335 0.4573561220916043 0.1194171261960574 +Response to retinoic acid 2 13 2.0185220630108067 0.0435369187406942 3.655339805825242 12.310679611650484 0.1226036573439472 0.4934300310013219 2.191697845880859 2.2394482946345504 0.9803317092709772 0.3045449067345129 0.0567667721825774 0.225458320485449 0.0932703984994284 0.1411134338084059 0.2675058784158126 +Signal release 16 67 2.017196524486736 0.04367500863715 12.5 53.04611650485437 0.3585348837247343 0.6675945143497025 5.0147839686697555 6.933127837959904 0.6529635649752229 0.3113638808040089 1.0 0.0175890594143828 0.0522704465941486 0.033678439255046 0.0959665245196598 +Synaptonemal complex organization 0 6 2.0132342416142617 0.0440899925481605 1.470873786407767 6.174757281553398 0.723394588880887 0.4361908449153728 1.1810092004903878 0.7330900746788283 0.8281604841906476 0.2971095774097388 0.0107410366228137 0.0461123069087121 0.0912026913027489 0.2167775624926856 0.3928150466925536 +Inflammatory response 10 79 2.012861417720755 0.0441292104787633 13.228155339805824 68.3883495145631 0.4116983048649594 0.5194837377797665 5.6022172704029956 8.769134982645609 1.0984550499812151 0.3566163019943059 0.2631325096417319 0.0096962927124798 0.0168888966330317 0.1377776475902275 0.3824574525987478 +Positive regulation of myeloid leukocyte cytokine production involved in immune response 3 7 2.0119970034659183 0.0442202528661932 2.5145631067961167 6.997572815533981 -0.0869388423382872 0.5579532941825486 1.8214689349448123 0.87438962457916 0.8627406417743261 0.2943145091140562 1.0 0.0727733471903131 0.1419203898220533 0.3236592382947187 0.039942155971048 +Calcium import into the mitochondrion 4 8 2.009180273342823 0.0445180189656144 2.4563106796116503 6.04126213592233 0.8091317576129835 0.2214807715451704 1.7082137325011066 1.2010296388602073 1.3762222767333927 0.2421218388926935 1.0 0.0550816697898294 0.1084298440104649 0.032628233248221 0.0001590313802548 +Aminoglycan catabolic process 4 5 2.009173690680246 0.044518716817697 2.6893203883495147 4.728155339805825 0.5164809724591738 0.1764823388548578 1.1619294817897845 0.7656988020633148 1.69808407883546 0.2279588459746903 1.0 1.0 1.0 0.0025975272437437 0.0001590313802548 +Glycosaminoglycan catabolic process 4 5 2.009173690680246 0.044518716817697 2.6432038834951457 4.665048543689321 0.5167433573606753 0.1777854895826483 1.1305026922003756 0.6751064263980151 1.6910244329591049 0.2288538535307848 1.0 1.0 1.0 0.001983278822638 9.662113775844424e-05 +Phosphatidic acid metabolic process 1 7 2.0065509383604665 0.0447974997694347 2.2233009708737863 6.235436893203883 0.8816881639607732 0.2856229767394486 1.614148841412113 1.5439850574626743 1.1927985254107716 0.2824496640110863 0.0277087127163546 0.1155957163384056 0.2202973788945578 0.1292409073430241 0.3630866560691931 +Lysosomal transport 11 51 2.0022127632146387 0.0452618535765794 10.274271844660197 41.317961165048544 0.2711798693300527 0.4597127484771267 4.560810075793522 6.516846556965687 1.3243780303643906 0.3539546843782676 1.0 0.3893684484717567 0.26028156886766 0.0397562781277324 0.0045140295573035 +Cell cell adhesion 30 117 1.9996747000588653 0.0455354018413278 23.050970873786408 98.0509708737864 -0.1429190746646203 0.6601701095788187 9.456585727444704 13.145925723777465 0.869400746956233 0.3243063932634235 0.3526312896306551 0.5601390538223876 0.3227423961439741 0.4842481188362782 0.1065568313180756 +Regulation of phagocytosis 1 19 1.994637381468847 0.0460824434547595 3.3179611650485437 14.968446601941748 0.3209190136413688 0.5915166201342027 2.2957046675959747 2.326811751466005 0.7840787087563237 0.2941325518261171 0.0454466093944714 0.0173338143393145 0.0628860756551618 0.2781824052676386 0.3487517012854798 +Neuron projection guidance 7 27 1.9943675303476824 0.0461119042097073 5.662621359223301 23.189320388349515 0.4437647002001748 0.5678522712486597 2.931294310088859 4.519975354803488 0.8912373776728286 0.311775964869191 1.0 0.4708564934485306 0.3653214792058465 0.4057604474152967 0.3276283474463078 +Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 2 6 1.9942128086877835 0.0461288029616602 1.3762135922330097 4.337378640776699 0.2175368846901604 0.5105338436956407 1.0711201073994667 1.1192321060068815 0.9782234884268414 0.2998128854711316 1.0 0.0814971443263516 0.1581956798045988 0.3559534457378639 0.0541965943180989 +Lipid homeostasis 4 29 1.983452161526558 0.0473169455972426 7.665048543689321 25.939320388349515 0.8425417577103904 0.3366972259521467 2.992619034719237 3.7336969269092393 1.1648658675422845 0.295769208633365 0.0034334205639766 0.058039929090825 0.0079741048982492 0.0499487852123864 0.0482032035846316 +Peptide catabolic process 4 10 1.9833639672246253 0.0473267889583666 3.871359223300971 10.351941747572816 1.5413280472635258 0.1625248535751528 1.454973091229298 0.9501768442987896 1.1353491763523988 0.2229381591694359 1.0 0.0035263772514821 0.0007241732031318 0.000963248429344 0.0017585862412997 +Neuron recognition 0 7 1.9832732471330383 0.0473369160193795 1.9368932038834952 6.189320388349515 0.7447638338644241 0.3705616592284931 1.1064234596616862 1.175429078554095 1.011644937344681 0.2892876339238009 1.0 0.1239247827595126 0.23510055646516 0.4957890007184933 0.7529706296614391 +Long term synaptic potentiation 4 11 1.976710857981203 0.0480743227690394 3.012135922330097 9.730582524271844 0.4069972937780292 0.4936148854997918 1.5319726166057843 1.7661148877091215 0.9317897164603502 0.2968501206773379 1.0 0.1878492321971458 0.3439334989552355 0.2871762535363917 0.3622356612907112 +Regulation of organic acid transport 4 13 1.973397985785973 0.048450236926991 3.0266990291262137 9.95873786407767 0.5438090247089712 0.4615742763522461 1.7589620109651245 1.3814816722984091 0.8909245759390145 0.2944812864916606 1.0 0.0060764540616979 0.0233124310373507 0.1211421538065826 0.0063149437065281 +Natural killer cell activation 4 10 1.9708516730056036 0.048740844229471 1.9878640776699028 7.638349514563107 0.4542633516701123 0.4463177415359376 1.4133030584142874 1.2337429018002426 0.94211286358969 0.2816177888765198 0.0392200518637268 0.1604648724397155 0.2983459236646945 0.224257489169728 0.1034478004905659 +Photoreceptor cell maintenance 4 5 1.9702257506126044 0.048812503582079 1.0728155339805825 2.825242718446602 0.6076970291504733 0.4317281000950851 0.864363975693771 0.7591152804738689 1.1463181416253934 0.3135328624897718 1.0 1.0 1.0 0.4160065505344545 0.0201372619620155 +Retina homeostasis 4 5 1.9702257506126044 0.048812503582079 1.308252427184466 3.648058252427184 0.2318874334800132 0.4489449786931666 0.9162131086992596 0.7820319044126499 1.1480322715279956 0.3097443808527051 1.0 1.0 1.0 0.5855309260576435 0.0957448321565225 +Positive regulation of fibroblast proliferation 0 5 1.968321253225453 0.0490310860637119 2.2184466019417477 6.686893203883495 0.3895883807436451 0.5595634829228668 1.7847382975769774 1.3764746931300986 0.7848609912150716 0.3030107819452191 1.0 0.1239247827595126 0.23510055646516 0.4957890007184933 0.7529706296614391 +Circulatory system process 21 83 1.9658404459473868 0.0493170441218795 17.152912621359224 72.00970873786407 0.7968086684699157 0.4206667688960129 5.8797345113877215 8.195718922280731 1.282615010632819 0.3676426088525382 0.2323046488392658 0.0266491171010429 0.0021054046256833 0.0143506567945501 0.0035015274557508 +Protein demannosylation 1 5 1.965642281434059 0.0493399464062254 0.7961165048543689 2.1820388349514563 0.2307809235972916 0.4306456874461153 0.7896075380190603 1.1483917494227882 1.3735216221874975 0.3274782947314177 1.0 1.0 0.1253337423142017 0.2897526236095206 0.1462762019757018 +Positive regulation of cell cell adhesion 4 30 1.9636330135075557 0.0495726660083537 6.548543689320389 29.79126213592233 0.2392641305343646 0.6381877105722645 3.259798197270223 3.572429669961151 0.7925488926612984 0.3104905639319101 0.1269454833782609 0.447598689406909 0.0311592891852558 0.1843027980199457 0.2631022349918105 +Regulation of peptidyl tyrosine phosphorylation 8 34 1.9626813678967625 0.0496832094283878 6.378640776699029 27.87135922330097 0.1802199323220069 0.6349333342581757 3.0857219100090787 4.315860914587658 0.7372095149693096 0.2961615496176262 1.0 0.1123544518992548 0.3237138230889217 0.5679451642648087 0.2424849321942219 +Protein lipid complex subunit organization 1 6 1.960780236132182 0.0499046645283383 1.1310679611650485 5.281553398058253 0.8340606377827192 0.3186795511043827 1.091585568626531 0.8580569122292387 0.9998971723912514 0.2555622550899711 0.0203181815952763 0.0858288536093336 0.1662183776826317 0.0757571260003459 0.2355870590704462 diff --git a/msigdb_gobp/metrics.json b/msigdb_gobp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..50a5d8a5bcfc0f03f6c855ac5ab491a9deda2e8f --- /dev/null +++ b/msigdb_gobp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 6663, + "title": "Average number of proteins per term", + "value": 20.914302866576616 +} \ No newline at end of file diff --git a/msigdb_gobp/paths.json b/msigdb_gobp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a7f6f435eea83d8b569d6994a1759ce66781be5f --- /dev/null +++ b/msigdb_gobp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gobp/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gobp/result.tsv b/msigdb_gobp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..4fa392d3b4903a20de117d53d14250802d6dd6e1 --- /dev/null +++ b/msigdb_gobp/result.tsv @@ -0,0 +1,2230 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Organic acid transport 0.5911005354900233 3.2169020606394807 0.0012958282596384 0.9998230604995464 0.0198942481427907 53 P11166,O95563,Q9UBX3,P23786,Q96H78,P80404,O43772,P53985,P14174,Q01650,Q7L0J3,O14678,P31751,P30825,P41440 15 +Positive regulation of cytokine production 0.5432915766463057 3.073877781514328 0.0021129597534974 0.999999242729741 0.0292695443608182 67 P30511,P14174,Q01650,P14373,Q9NY93,P05067,Q9BY67,Q7Z434,O75787,O75116,Q13049,P23396,Q8WXW3,P78536,P41440,Q9NRA0,Q9NUQ9,Q01082,O75955 19 +Signal transduction by p53 class mediator 0.5690799130087177 2.989005817904187 0.002798868022501 0.9999999922455912 0.0370017016546123 50 P46379,Q8N2F6,Q9UNS2,Q01664,Q7LG56,P14174,Q13573,O75844 8 +Organic anion transport 0.5544764551582739 2.947081804897515 0.0032078832748594 0.999999999496019 0.0413009992674349 56 Q86VD7,Q14728,Q01650,P14174,Q7L0J3,Q9HC21,Q9Y619,P11166,O00400,O95563,Q9UBX3,P80404,Q9BQT8,Q8TB61,P53985,Q15758,P30825,P55011,Q9H2D1,P07602,P41440,Q9Y6M7 22 +Lytic vacuole organization 0.6568010741394651 2.94300553477562 0.0032504260700367 0.9999999996207644 0.0414896339169637 32 Q14108,P50897,Q9HC07,O75787,Q96ED9,P10253,O14773,P54802,Q8NHS3,O75503,P11117,Q9NWW5,Q14457 13 +Positive regulation of immune system process 0.4586983402443895 2.917267887286333 0.0035311235523745 0.9999999999419382 0.0444761365396433 129 P23246,P46379,Q9HCL2,P30511,P14174,Q01650,Q9NY93,P05067,Q06481,Q9BY67,P02786,Q7Z434,P30825,P00813,P23396,Q15046,Q15233,P12956,P04439,O96028,O15400,P78536,Q9NPF0,Q9BX67,Q9NRA0,P31749,Q9NUQ9,P51809,Q9NQT5,O95219,Q99538,Q9H2U1,P26583,P49770 34 +Intrinsic apoptotic signaling pathway by p53 class mediator 0.7355082178337271 2.8921516379023013 0.0038261323027704 0.9999999999919263 0.0474739656114696 19 P46379,P14174 2 +Positive regulation of nf kappab transcription factor activity 0.6428122758965912 2.847519541283169 0.0044061389020819 0.9999999999998334 0.0528974837920219 32 P19474,P02786,O60858,P14373,P05067,O75955,Q96HY6,P41440,P32929,Q13049,P60900 11 +Anion transport 0.4984930148710939 2.781915897093492 0.0054039041952496 0.9999999999999998 0.0617134508947077 84 Q14728,Q86VD7,P14174,Q01650,Q7L0J3,Q9H813,Q9HC21,Q9Y619,Q9Y666,Q9UHG3,P11166,P21796,O00400,O95563,Q9UBX3,Q9BQT8,P53985,Q8TB61,P80404,Q15758,P30825,O43865,P55011,Q9H2D1,P07602,P45880,P51790,P51798,P41440,Q9Y6M7,O43681 31 +Carboxylic acid transport 0.5977319524394277 2.7627288877296485 0.0057320356180525 1.0 0.0642972278166402 38 P07602,P53985,P14174,Q01650,Q7L0J3,P30825,P41440 7 +Regulation of lymphocyte activation 0.5296648545507205 2.755988875979018 0.0058514987010116 1.0 0.0650893753670127 58 Q9NUQ9,Q9HCL2,P22466,P14174,P12956,P30825,P00813,O96028 8 +Organic acid transmembrane transport 0.6071028247263481 2.751664881363741 0.0059293162888811 1.0 0.0657354982243181 35 P11166,O95563,Q9UBX3,P23786,P53985,O43772,Q01650,O14678,P30825,P41440 10 +Membrane lipid metabolic process 0.5703713030549674 2.7454731332926507 0.0060423714727066 1.0 0.0665459853266855 44 P16278,P04066,P07602,Q8NBX0,P50897,Q16739,Q8NCC3,O60512,Q9NWW5,Q9NRA0,Q969N2,Q96G23,P06280 13 +Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator 0.838948287980341 2.7400022258451764 0.006143876829088 1.0 0.0675522298881409 12 P46379,P14174 2 +Cell recognition 0.671169243140514 2.7120148033451357 0.0066875606168268 1.0 0.0723358353275348 26 P78371,Q9BY67,Q8WTV0,P45880,P15291,P05067 6 +Regulation of leukocyte apoptotic process 0.7753513610667794 2.7081112962696374 0.0067667325998532 1.0 0.0728380279690183 15 P00813,Q9Y4G8,Q9HCL2,P14174 4 +Transmembrane receptor protein serine threonine kinase signaling pathway 0.530710672237221 2.705191192284207 0.0068265086404599 1.0 0.0729995014956379 54 Q8WUH2,P49354,Q06481,Q92896,Q9UIQ6,Q8N0X7,P08670,Q01082,Q8N3R9,Q13573,Q8N1F7,P78536 12 +Endocytosis 0.4231852930337123 2.687989807314321 0.0071883590830934 1.0 0.0750721576342502 139 Q14108,Q08380,O15118,Q8WTV0,P84095,Q5KU26,O14976,O00291,Q5VW38,P05067,P35579,P11717,P20645,Q06481,P02786,Q96ED9,Q9BZG1,Q14457,Q9NZM3,P50897,Q96RU3,Q13464,P51790,P30533,Q9NPF0,P41440,Q9H223,Q14185,Q15075,Q9Y5X1,O15260,Q99523,P57105,O75955,Q9NUN5 35 +Diacylglycerol biosynthetic process 0.9925844548201042 2.6773436673515096 0.007420847443228 1.0 0.0770172998663992 2 Q9HCL2 1 +Protein localization to lysosome 0.6975174529146375 2.656356131934626 0.0078990147157549 1.0 0.0789089235808547 18 Q14108,P20645,O75116,Q99523,Q9NUN5 5 +Positive regulation of immune effector process 0.5634489974350555 2.654071914493613 0.0079526876027438 1.0 0.0789089235808547 43 Q9NUQ9,Q9BY67,Q06481,P02786,Q7Z434,P51809,P30511,P14174,Q01650,O15400,O95219,P04439,O96028,Q9NY93,Q9H2U1,Q9NRA0 16 +Anion transmembrane transport 0.5303005402622027 2.6538297626689755 0.0079583966150884 1.0 0.0789089235808547 50 Q86VD7,Q14728,Q01650,Q9HC21,Q9Y619,Q9Y666,Q9UHG3,P21796,O95563,Q9UBX3,Q9BQT8,P53985,Q8TB61,Q15758,P30825,P55011,Q9H2D1,P45880,P51790,P51798,P41440,Q9Y6M7 22 +Phospholipid homeostasis 0.9829717110683872 2.6383702840109584 0.0083305564203017 1.0 0.0810313831072566 2 Q9HCL2 1 +Positive regulation of cell activation 0.5425640347411826 2.6311929557248948 0.0085085712388426 1.0 0.0824020496575704 47 P23396,Q9NUQ9,Q9HCL2,Q15046,P04439,P51809,P02786,P30511,P14174,P12956,O95219,P30825,Q9NPF0,P00813,O96028,Q9NRA0,P31749 17 +Cytokine production 0.4602194512960098 2.619640125342265 0.0088022601708579 1.0 0.0841455660235674 112 Q9HCL2,P30511,P14174,Q01650,P14373,Q9NY93,P05067,P19474,Q06481,Q9BY67,Q7Z434,O75787,O75116,Q9Y6M1,Q13049,P23396,Q8IV08,Q8WXW3,P78536,P41440,Q9NRA0,Q9NUQ9,P17655,Q01082,O75955 25 +Regulation of dna damage response signal transduction by p53 class mediator 0.8208863342623468 2.595645000331399 0.0094413556572425 1.0 0.0886024686538131 11 Q9UNS2,P14174 2 +Regulation of lymphocyte apoptotic process 0.8657942114568327 2.590621536522432 0.0095802786219705 1.0 0.089518544204878 9 Q9HCL2,P14174 2 +Pigment metabolic process 0.608651610158586 2.5516277957939653 0.0107220994093213 1.0 0.0968039950735882 31 P22830,P00813,O75027,P30519 4 +Neuron death 0.4783634111531785 2.538717014929464 0.0111259776198344 1.0 0.0994929899647726 76 Q99720,Q01105,P50897,P17655,P30511,Q15392,Q13464,O95831,Q96A26,Q15375,Q92542,P31751,P07196,Q99538,Q969N2,Q9UMX5,P05067 17 +Response to oxygen levels 0.4786953020913095 2.5349967923035637 0.0112448355717058 1.0 0.100300320501039 71 P11166,Q9Y487,P02786,P00846,P80404,P17655,P30519,O95831,P02545,O75116,O43707,Q96A26,P00813,O75592,P78536,Q14457,P55786 17 +Endothelial cell proliferation 0.6727317418258284 2.5318640964948536 0.0113457956473663 1.0 0.100844157836362 19 Q8WTV0,O94788,P25705,P57105,P78536 5 +Dna damage response signal transduction by p53 class mediator 0.6976100889097689 2.5284372786977434 0.0114571555578757 1.0 0.100844157836362 17 Q9UNS2,O75844,P14174 3 +Vacuolar acidification 0.817407679358086 2.5242196917270805 0.0115955438250106 1.0 0.1019275837810628 10 P50897,Q9Y487,Q93050,Q9NWW5,O75503 5 +Immune effector process 0.474370638976309 2.522648269774979 0.0116474836513349 1.0 0.1022016065967495 84 Q92538,P30511,P14174,Q01650,Q9NY93,P05067,Q9UQ84,Q06481,Q9BY67,P02786,Q7Z434,P00813,P33176,Q15046,P04439,O96028,O15400,P78536,P11274,Q9NRA0,Q9NUQ9,P51809,Q9NQT5,O95219,Q9H2U1 25 +Negative regulation of receptor binding 0.9530348805273272 2.5159387629686276 0.0118715807629021 1.0 0.1035770013966835 2 P10586 1 +Regulation of blood pressure 0.6584916730900743 2.5109763076607043 0.0120397777158254 1.0 0.1044544777611261 22 Q9HB40,P42785,Q9UIQ6,Q9NZ08,P42892,P09493 6 +Anatomical structure maturation 0.594496106445743 2.509685396042464 0.0120838765105331 1.0 0.1047007401686373 32 O75503,O94788,P05067,P22466 4 +Plasma membrane organization 0.5665695735425369 2.4993046597267807 0.0124437281156259 1.0 0.1072607508854023 37 P35579,P41440,Q9HD42,Q16739,P16615,Q9Y5X1,Q01082,Q8N3R9,O75955,Q9UQB8,Q96CP7 11 +Fatty acid transport 0.6687920970373055 2.4905247243204744 0.0127554620650831 1.0 0.1093817808747092 18 P11166,P23786,O43772,P14174,O14678 5 +Lymphocyte apoptotic process 0.6655849812305508 2.489858864102985 0.0127793831652667 1.0 0.1094225158212224 19 Q9HCL2,P14174 2 +Positive regulation of production of molecular mediator of immune response 0.6360017157346348 2.4891657351438705 0.0128043260618724 1.0 0.1094225158212224 26 P02786,Q7Z434,P30511,P14174,Q01650,P04439,O96028,Q9NY93,Q9H2U1,Q9NRA0 10 +Sphingolipid metabolic process 0.5746113616372682 2.4890226753042666 0.0128094795648436 1.0 0.1094225158212224 34 P16278,P07602,P50897,Q16739,Q8NCC3,O60512,Q9NWW5,Q9NRA0,Q96G23,P06280 10 +Calcium ion import 0.690095019166495 2.4863819037458477 0.0129049393656388 1.0 0.1099560242880456 17 P21796,Q9NWR8,P16615,Q9H4I9,P14373,Q9BPX6,O75844,Q8IYU8,Q9NRA0 9 +Positive regulation of lipid localization 0.7494208542089379 2.471017209061509 0.0134729335059193 1.0 0.1137771304815473 14 Q8WTV0,P14174 2 +Positive regulation of protein binding 0.6322171389450226 2.4648473609074313 0.0137071629924405 1.0 0.1151712824951217 26 P19474,Q9Y4G8,P41440,P05067,Q96D46 5 +Neuron apoptotic process 0.513666552123283 2.4633661241606215 0.0137639286061099 1.0 0.1155025898016508 49 Q99720,Q01105,P50897,Q13464,Q96A26,O95831,Q15375,P31751,P07196,Q99538,Q969N2,Q92542,P05067 13 +Ph reduction 0.7467736136221573 2.4576307839134186 0.0139856876953876 1.0 0.1165913675428153 14 P50897,Q9Y487,Q93050,Q9NWW5,O75503 5 +Regulation of ph 0.6417022875877185 2.457297687164824 0.0139986633699913 1.0 0.1165913675428153 24 P50897,Q9HC07,Q9Y487,O75787,Q93050,Q9NWW5,O75503,Q9Y6M7 8 +Regulation of cellular ph 0.6417022875877185 2.457297687164824 0.0139986633699913 1.0 0.1165913675428153 24 P50897,Q9HC07,Q9Y487,O75787,Q93050,Q9NWW5,O75503,Q9Y6M7 8 +Biological adhesion 0.4209474743580996 2.4554229206947578 0.014071892683203 1.0 0.1170549574883672 200 P07942,Q08380,Q9HCL2,Q8WTV0,Q9BQT9,Q13136,Q92797,Q9UM22,O00192,Q9UQB8,P05067,P46939,P35579,Q9BY67,Q96JJ3,P02786,P16615,P80404,O75116,Q15375,Q9UBT7,P30825,P00813,O14936,P23396,P12814,Q13464,O43707,Q13641,Q14168,Q96F07,P09493,P78536,Q9BX67,P41440,P11274,Q14185,Q9NUQ9,P35580,P15291,P57105,O75955,P10586 43 +Regulation of deacetylase activity 0.9373798407031032 2.4512776688269713 0.0142350096018977 1.0 0.1179699862903538 2 Q9NRA0 1 +Positive regulation of cytokine production involved in immune response 0.7618207858869399 2.4364098240913408 0.0148338675397914 1.0 0.1214226774172362 13 Q7Z434,P30511,P14174,Q01650,Q9NY93,Q9H2U1,Q9NRA0 7 +Positive regulation of heterotypic cell cell adhesion 0.9327107937379828 2.431908260218652 0.0150195109765465 1.0 0.1218940336622771 2 P41440 1 +Positive regulation of toll like receptor 3 signaling pathway 0.9327107937379828 2.431908260218652 0.0150195109765465 1.0 0.1218940336622771 2 P41440 1 +Production of molecular mediator of immune response 0.5437595045726402 2.4311348531743917 0.0150516112874883 1.0 0.1220059440493123 41 Q9UQ84,P20585,Q96FV9,P02786,Q7Z434,P30511,Q9NQT5,P14174,Q01650,P04439,O96028,Q9NY93,Q9H2U1,Q9NRA0 14 +Calcium ion import into sarcoplasmic reticulum 0.9316121944520728 2.427345119874868 0.0152097794916952 1.0 0.1222200622669112 2 P16615 1 +Regulation of response to external stimulus 0.3983060118200494 2.425855382905603 0.0152723547247695 1.0 0.1222200622669112 150 P30511,P14174,Q9UMX5,Q96G23,P05067,P60900,P19474,Q06481,Q9BY67,P28070,Q7Z434,P80404,P00813,O75592,O43657,O94874,O14936,P55011,Q15046,Q15233,Q13641,P12956,Q13573,P78536,Q9BX67,P11274,P80303,Q9NUQ9,Q96RK4,P51809,Q9NZ08,Q9NWH9,O95219,P10586,Q99538,O75844,P23246 37 +Lymphocyte homeostasis 0.8261940106847937 2.418372790215374 0.0155900956352201 1.0 0.1245525266396547 9 Q9HCL2,P14174 2 +Regulation of lysosome organization 0.9291403460587744 2.4170702164314424 0.0156459986201296 1.0 0.1248494476717647 2 Q14457 1 +Negative regulation of lymphocyte apoptotic process 0.8857688778480467 2.4139198329674865 0.0157819343226663 1.0 0.125483327436666 7 Q9HCL2,P14174 2 +Negative regulation of leukocyte apoptotic process 0.8857688778480467 2.4139198329674865 0.0157819343226663 1.0 0.125483327436666 7 Q9HCL2,P14174 2 +Negative regulation of cell population proliferation 0.443257612841917 2.4117007019803194 0.0158783100033093 1.0 0.1260991413016089 112 P98175,O94788,Q71SY5,P02545,Q9Y366,Q96G23,P05067,Q9NR77,P22466,Q06481,Q15392,Q96DY7,Q13049,Q14457,Q96TA1,Q01664,Q13641,Q9Y4G8,P52756,P09493,P25705,P15291,P57105 23 +Membrane invagination 0.6761462610359208 2.4077704447173094 0.0160502695298723 1.0 0.1262555925509554 17 P35579,Q06481,P84095,Q9Y5X1,P51790,Q14457,Q14185 7 +Regulation of immune effector process 0.4975239382581582 2.4026448808979612 0.0162769854421838 1.0 0.1262555925509554 54 Q96FV9,P30511,P14174,Q01650,Q9NY93,Q9BY67,Q06481,P02786,Q7Z434,P04439,O96028,O15400,P11274,Q9NRA0,Q9NUQ9,P51809,Q9NQT5,O95219,Q9H2U1 19 +Disaccharide metabolic process 0.9244712990936542 2.3976324880684574 0.016501412213735 1.0 0.1276990819745835 2 P15291 1 +Developmental maturation 0.5275721794479287 2.3939764072628167 0.0166668208252562 1.0 0.1288294978639009 44 Q8N2A8,P22466,O94788,P07196,Q12834,O75503,P05067 7 +Appendage development 0.6477878324499922 2.3843598663612955 0.0171088626488522 1.0 0.1316355101954995 19 Q9NX62,O94788,P42892,Q9Y366,O75592 5 +Response to thyroglobulin triiodothyronine 0.9209008514144454 2.382742284792231 0.0171842197940224 1.0 0.1319755534143575 2 P16278 1 +Regulation of b cell activation 0.6463016562222527 2.3754919673793244 0.0175255738522943 1.0 0.1342239061207188 19 P02786,Q9NQT5,P14174,Q9NPF0,P00813,O96028 6 +Tetrapyrrole metabolic process 0.6284991422211769 2.3742587220640834 0.0175842244010386 1.0 0.1345162883859021 24 P22830,Q9NUN5,P30519,O14678,O75027,Q7KZN9 6 +Regulation of systemic arterial blood pressure by hormone 0.9176050535567132 2.368977473460782 0.0178373398355622 1.0 0.1351178727223505 2 P42892 1 +Leukocyte apoptotic process 0.623459580989146 2.3685486402745477 0.017858032049121 1.0 0.1351178727223505 25 P00813,Q9Y4G8,Q9HCL2,P14174 4 +Phosphatidylglycerol metabolic process 0.7694379525335135 2.3557287181527964 0.0184864126870061 1.0 0.1382435103630996 11 Q9HCL2 1 +Cell activation 0.3931004761585193 2.3550154867086595 0.0185219337500999 1.0 0.1383538616333136 149 Q92538,P46379,P26038,Q9HCL2,P30511,P14174,Q9Y6D9,P05067,P35579,Q9UQ84,P22466,Q9BY67,P02786,P80404,Q96L92,P30825,P00813,Q92542,P24390,P23396,P12814,Q15046,Q8WXW3,P12956,P04439,O96028,P78536,Q9NPF0,P11274,Q9NRA0,P31749,Q9NUQ9,P51809,O95219 34 +Notch receptor processing 0.9137599560560276 2.352894295592957 0.018627928624777 1.0 0.1389897966706487 2 P78536 1 +Positive regulation of tumor necrosis factor superfamily cytokine production 0.7259395415000719 2.351538531452004 0.0186959531620622 1.0 0.1393413153454374 14 Q9NRA0,P05067,P14174 3 +Embryonic appendage morphogenesis 0.7441321407339222 2.349087395834446 0.0188194889604869 1.0 0.1401053127862841 13 O94788,P42892,Q9NX62 3 +Regulation of production of molecular mediator of immune response 0.5791748713131837 2.3442636382935476 0.0190646900143027 1.0 0.1417723544255573 31 Q96FV9,P02786,Q7Z434,P30511,Q9NQT5,P14174,Q01650,P04439,O96028,Q9NY93,Q9H2U1,Q9NRA0 12 +Regulation of glycoprotein metabolic process 0.7426522464936094 2.3417412477964192 0.0191940167393103 1.0 0.1425749537726027 13 Q99805,Q9NQX7,Q92542,Q9BXS4 4 +Porphyrin containing compound metabolic process 0.6400019402365673 2.3378024242889417 0.0193974998023258 1.0 0.1436061568698857 19 P22830,P30519 2 +Lymphocyte activation 0.4393169526381608 2.3365339468617727 0.019463430487576 1.0 0.1439343366689446 110 P46379,P26038,Q9HCL2,P30511,P14174,Q9Y6D9,P35579,Q9UQ84,P22466,Q9BY67,P02786,Q96L92,P30825,P00813,Q92542,P24390,P23396,Q8WXW3,P12956,P04439,O96028,P78536,Q9NPF0,P31749,Q9NUQ9,P51809 26 +Cellular monovalent inorganic cation homeostasis 0.5986802088306888 2.3310177466166504 0.0197524239233581 1.0 0.1457479519394635 28 P55011,P50897,Q9HC07,Q9Y487,O75787,Q93050,Q9NWW5,O75503,Q9Y6M7 9 +Positive regulation of intracellular signal transduction 0.3965071165922645 2.3298711218473103 0.0198129637343913 1.0 0.1460329395600105 160 O15344,Q86VI3,P14174,P14373,O00291,Q9NY93,Q9UMX5,P05067,P19474,Q8WVQ1,P02786,Q7Z434,O75116,P00813,P32929,Q13049,Q14457,P29372,P55735,Q13464,O43707,O60858,Q9Y4G8,Q13641,Q9NRA0,Q15555,O75569,Q9NWH9,O60826,P23246 30 +Long chain fatty acid transport 0.7214301478753936 2.3284023663562565 0.0198907481249217 1.0 0.1464442593992858 14 P11166,P23786,O43772,P14174,O14678 5 +Mitochondrial transmembrane transport 0.4854241253243176 2.3272540997522384 0.0199517451767423 1.0 0.1467312120448503 57 Q9BSK2,O95563,P21796,Q9NWR8,P23786,P00846,Q9H4I9,O43772,O95831,P25705,O75027,O75964,Q8IYU8 13 +Blood vessel endothelial cell migration 0.624183499016974 2.322574942578816 0.0202019981207246 1.0 0.1482443981039519 23 Q8WTV0,P25705,P42785,P78536 4 +Regulation of lysosomal lumen ph 0.8627484149277616 2.3197375127950703 0.0203550812218067 1.0 0.1492034171407022 7 O75503,Q9NWW5,O75787,P50897 4 +Regulation of neurotrophin trk receptor signaling pathway 0.9055204614117004 2.31834273780482 0.0204307014514135 1.0 0.1492650918539129 2 Q96F07 1 +Positive regulation of neurotrophin trk receptor signaling pathway 0.9055204614117004 2.31834273780482 0.0204307014514135 1.0 0.1492650918539129 2 Q96F07 1 +Cellular response to retinoic acid 0.8020721513607023 2.3116950789396107 0.0207944927771905 1.0 0.1511557338561986 9 O94788 1 +Suppression of viral release by host 0.8322080085882975 2.309900630846877 0.0208936561431125 1.0 0.1511557338561986 8 O60858,Q13049,P19474 3 +Positive regulation of chemokine production 0.8009023698832485 2.30648786509592 0.0210833874157712 1.0 0.1515411114900577 9 P78536,Q13049,P05067,P14174 4 +Cellular response to hydrogen peroxide 0.6212387008241634 2.3040645119018413 0.0212190224935668 1.0 0.1515702301644994 23 P23396,Q99720,Q9NWH9,O95831,Q14457 5 +Membrane protein proteolysis 0.7166992659881759 2.3040634532125415 0.0212190819141178 1.0 0.1515702301644994 14 P35579,Q9Y5X1,Q9NZ08,Q13464,Q16740,P78536,Q92542,Q9H300,Q8TCT8 9 +Transforming growth factor beta receptor signaling pathway 0.573054976294531 2.3006298174933937 0.021412564149345 1.0 0.1523230411817824 31 Q8WUH2,Q06481,Q92896,Q8N3R9,Q13573,P78536 6 +Protein processing 0.4880740469809496 2.284054095375942 0.0223683519418589 1.0 0.1575479164784419 51 P35579,Q9Y366,Q92896,P17655,O75787,Q15392,O75976,Q96F07,Q9BXS4,Q9H9S5,P42892,O75503,Q9NQH7,O75844,Q92542,Q9H300,Q969M3,P78536 18 +Monovalent inorganic cation homeostasis 0.5629713028659461 2.282382165176677 0.0224667873589194 1.0 0.1579073883675955 32 P55011,P50897,Q9HC07,Q9Y487,O75787,Q93050,Q9NWW5,O75503,Q9Y6M7 9 +Regulation of synapse structure or activity 0.5469848465145812 2.281464425611921 0.0225209794774776 1.0 0.1581214818318584 34 Q14012,P50897,Q9BQT9,Q14203,Q13641,Q15375,Q12834,Q7L576,Q9UQB8,P05067 10 +Apoptotic cell clearance 0.7643188282280228 2.279988966415004 0.0226083428781016 1.0 0.1584010395339551 10 Q8WTV0,P84095 2 +Response to transforming growth factor beta 0.5317035074765277 2.278290507457164 0.0227092748561041 1.0 0.1589410697124182 39 Q8WUH2,P49354,Q06481,Q92896,O75116,Q8N3R9,Q13573,P78536 8 +Lipid localization 0.4473176714116652 2.276458301057388 0.0228185936520393 1.0 0.1595386038861888 94 Q9H4L5,Q99720,Q14108,P11166,P07602,P22466,O15118,Q8WTV0,P23786,P61916,Q16739,O15260,O43772,P14174,O14678,P35790 16 +Regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.7519531243516707 2.2726199531806106 0.0230490921628081 1.0 0.1605312052585606 11 Q8N2F6,P14174 2 +Membrane protein ectodomain proteolysis 0.7517588366725143 2.271691967371752 0.0231051216933753 1.0 0.1605312052585606 11 P35579,Q9Y5X1,Q9NZ08,P78536,Q92542,Q8TCT8 6 +Leukocyte homeostasis 0.7095830145577758 2.267324537810267 0.0233704075651295 1.0 0.1622052350067272 14 P00813,Q9HCL2,P14174 3 +Plus end directed organelle transport along microtubule 0.8931612194452072 2.266292683235296 0.0234334691138295 1.0 0.1624736781534304 2 P33176 1 +Regulation of leukocyte proliferation 0.5818577233297785 2.262282105593108 0.0236799792890336 1.0 0.1640121642441072 29 P30825,Q9HCL2,P22466,P14174 4 +Adaptive immune response 0.491097538843237 2.2616840542464733 0.0237169306173579 1.0 0.1640975168260184 49 Q9UQ84,Q9NUQ9,P10321,Q9BY67,P02786,Q9NZ08,P30511,Q9NQT5,O15400,P14373,P04439,P00813,Q9BX67,O96028,P78536 15 +Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 0.5355219886225457 2.258772732604993 0.0238975255049214 1.0 0.1649141839762534 37 Q9UQ84,Q9NUQ9,Q9BY67,P02786,P30511,Q9NQT5,P04439,P00813,O15400,O96028,P78536 11 +Myotube differentiation 0.650019565577552 2.2585849424932176 0.0239092153265887 1.0 0.1649141839762534 17 P35579,Q8IV08,Q96TA1,Q99523,O75955,P41440 6 +Negative regulation of calcium ion import 0.8901400714089507 2.2535289459355514 0.024225817746458 1.0 0.1667527103767045 2 P21796 1 +Protein homooligomerization 0.4942523627487047 2.250673976452344 0.0244061941805455 1.0 0.1676479090979125 48 Q99720,Q06481,O94788,Q4G0X4,P14174,P32929 6 +Carbohydrate derivative transport 0.6124041774904068 2.2483067072085428 0.0245566393279113 1.0 0.1683342467508981 23 Q86VD7,P07602,P61916,Q8WTV0,Q9HC21,P41440 6 +Neuron maturation 0.9340536694808824 2.2472204109678353 0.0246259443645704 1.0 0.1684087072721939 5 O75503 1 +Positive regulation of adaptive immune response 0.6275500090555426 2.246702728013067 0.0246590317976038 1.0 0.1684087072721939 18 Q9NUQ9,P02786,P30511,P04439,P00813,O15400,O96028 7 +Transmembrane transport 0.4230409375172317 2.2417045500622796 0.0249804736221912 1.0 0.17001521526523 254 Q9BSK2,Q86VD7,Q8WTV0,O96008,Q07820,Q6NT16,Q15629,O43772,Q8IXU6,Q01650,Q96H78,Q7L0J3,Q9HC07,O75298,Q99442,O75027,P39210,Q9HC21,Q7KZN9,P05067,Q16625,P46939,Q9UHG3,P11166,P21796,Q8N4V1,O95563,Q70HW3,P22466,Q06481,Q9NWR8,Q9UBX3,Q9BQT8,P53985,Q8TB61,O95831,Q96GC9,P16615,O14678,O75251,Q8NHS3,Q9HD20,P30825,O43865,Q6P4Q7,Q9BPX6,P00403,P20674,P55011,P23786,P00846,P45880,O43707,P51790,O75964,P51798,P41440,P11274,Q9NRA0,Q9Y6M7,Q13423,Q9H4I9,Q99523,P25705,P31751,O75844,Q8IYU8 67 +Vitamin transport 0.7551654275315431 2.237163863371362 0.025275632224436 1.0 0.171673330796552 10 P11166,Q9H2D1,Q8WTV0,O14678,Q9NPF0,Q9HC21,P41440 7 +Iron ion homeostasis 0.6460753418283552 2.235842539012846 0.0253620873473032 1.0 0.1720851201579243 17 O75027,P30519 2 +Cell activation involved in immune response 0.5155988038370238 2.230780080250621 0.0256957000570057 1.0 0.1741713626447905 42 Q92538,Q9UQ84,Q15046,Q96FV9,P51809,P02786,P30511,Q9NQT5,P11274,O95219,P00813,Q9NRA0,O96028,P05067 14 +Collateral sprouting in absence of injury 0.884097775336443 2.2279541885713123 0.0258835700676274 1.0 0.1752664912201235 2 P05067 1 +Positive regulation of immune response 0.4479241761068051 2.2245500598819716 0.0261114583664701 1.0 0.1764509605433979 82 P46379,P49770,P30511,Q06481,Q9BY67,P02786,Q7Z434,P00813,P23396,Q15046,Q15233,P12956,P04439,O96028,O15400,Q9NRA0,Q9NUQ9,P51809,Q9NQT5,O95219,P26583,P23246 22 +Copulation 0.882724526229055 2.222132983674485 0.0262743198028965 1.0 0.1768341341885853 2 P00813 1 +Regulation of gamma aminobutyric acid secretion 0.8827245262290546 2.222132983674485 0.0262743198028965 1.0 0.1768341341885853 2 Q7L0J3 1 +Gamma aminobutyric acid secretion 0.8827245262290546 2.222132983674485 0.0262743198028965 1.0 0.1768341341885853 2 Q7L0J3 1 +Chemokine production 0.7410582282210113 2.22042954665085 0.026389623231261 1.0 0.1774309380321819 11 Q13049,P05067,P14174 3 +Neuropeptide signaling pathway 0.9652512854106784 2.2166025051238893 0.0266502662426297 1.0 0.1782730994135216 4 Q9Y4G8,P22466 2 +Regulation of immune response 0.3954436480645436 2.2164547358380404 0.0266603745870832 1.0 0.1782730994135216 136 Q07666,P23246,P46379,P30511,Q5KU26,P14373,Q8TCT8,P19474,Q06481,Q9BY67,P28070,P02786,Q7Z434,Q9NPR9,P00813,O43657,P23396,Q15046,Q15233,P12956,P04439,O96028,O15400,P41440,P11274,Q9NRA0,Q9NUQ9,P51809,Q9NZ08,Q9NQT5,O95219,O75955,P26583,P49770 34 +Negative regulation of collateral sprouting 0.8813512771216708 2.2163085449000306 0.0266703782210617 1.0 0.1782730994135216 2 Q8N0X7 1 +Positive regulation of cell junction assembly 0.7170006192747642 2.2134137825584936 0.0268691313144462 1.0 0.1790290219481553 13 Q9BQT9,P41440,Q13464,O75955 4 +Regulation of adaptive immune response 0.602198009496549 2.206549457444387 0.0273455513522897 1.0 0.1802209779033697 24 Q9NUQ9,P02786,P30511,Q9NQT5,P14373,P04439,P00813,O15400,O96028 9 +Pirna metabolic process 0.8786047789068908 2.204649986569236 0.027478665205485 1.0 0.1808469133455468 2 Q8N2A8 1 +Regulation of nervous system process 0.7259635249751917 2.2006181324083114 0.027763068844945 1.0 0.1820721729467214 12 O75116,Q9UQB8,P05067 3 +Positive regulation of t cell receptor signaling pathway 0.8772315297995026 2.19881587774622 0.0278910170412678 1.0 0.1827314125329082 2 P00813 1 +Negative regulation of glycoprotein metabolic process 0.9599128150772388 2.1965995018332887 0.0280490618441953 1.0 0.1834061816171475 4 Q9BXS4 1 +Transition metal ion homeostasis 0.5961562419621534 2.192126344284802 0.028370385000449 1.0 0.1849626959471548 25 P05067,O75027,P30519 3 +Regulation of anion transport 0.6946757221256089 2.1898648442337887 0.0285340402734559 1.0 0.1850721773848739 14 Q7L0J3,P14174 2 +Regulation of pinocytosis 0.9580312013817656 2.1895394337420178 0.0285576556576505 1.0 0.1850721773848739 4 Q06481 1 +Positive regulation of pinocytosis 0.9580312013817656 2.1895394337420178 0.0285576556576505 1.0 0.1850721773848739 4 Q06481 1 +Negative regulation of natural killer cell activation 0.8750343312276823 2.189474624179138 0.028562360965969 1.0 0.1850721773848739 2 P30511 1 +Enzyme linked receptor protein signaling pathway 0.4011512551656688 2.1859383657705447 0.0288201148692444 1.0 0.1855381314126181 131 Q8WUH2,Q92896,Q8N3R9,O00291,Q9UQB8,P11717,Q06481,Q9UIQ6,Q8N0X7,Q15375,P43490,Q96TA1,Q9Y4G8,Q96F07,Q13573,Q8N1F7,P78536,Q7L576,P49354,P08670,Q9NWH9,Q99523,Q01082,P31751,P10586 25 +Protein targeting to lysosome 0.693383607189664 2.18311918647008 0.0290270339914753 1.0 0.1865063910175507 14 Q99523,Q14108,P20645 3 +Positive regulation of amyloid beta clearance 0.8725624828343856 2.17895591320533 0.0293349434734395 1.0 0.1879410849649306 2 Q13464 1 +Transepithelial chloride transport 0.8711892337269992 2.173107713059979 0.0297722113379794 1.0 0.1898034330058315 2 P55011 1 +Positive regulation of mapk cascade 0.4739416155002341 2.1717934035349695 0.0298712494683877 1.0 0.1898034330058315 53 O15344,Q86VI3,Q13464,P14174,O75116,Q9Y4G8,Q13641,Q9UMX5,P05067,P29372 10 +Microtubule organizing center organization 0.4753515068151566 2.1665569107568463 0.0302686559681442 1.0 0.1913263574180769 51 Q9Y496,Q9HD42,Q08379,O94927,Q8IWJ2,P53985,Q14203,P52732,Q9H6D7,O75116,Q96CS2,Q96RK4,Q9UPN4 13 +Negative regulation of neuron projection development 0.6085021625389931 2.1636223423485204 0.0304933453889164 1.0 0.1918615157966449 20 Q9NR77,Q8N0X7,P08670,O14976,Q9NQX7,Q96G23 6 +Regulation of toll like receptor signaling pathway 0.7064934493146622 2.1603079299821117 0.0307488394910986 1.0 0.1928348273814263 13 Q9NPR9,P41440,Q06481 3 +Retinoic acid metabolic process 0.9738022546211856 2.159156993390936 0.0308379892833143 1.0 0.1929328850654682 3 O94788 1 +Response to food 0.7967228175538583 2.157138370774821 0.0309948846680723 1.0 0.1935509995720392 8 Q9UMX5,P53985 2 +Fatty acid transmembrane transport 0.7656481486550626 2.1480866274019803 0.0317068743523776 1.0 0.1955253884082774 9 P23786,P11166,O43772,O14678 4 +Positive regulation of b cell activation 0.6863357219043734 2.1462359708112646 0.0318541570877541 1.0 0.1959780689526372 14 P00813,P14174 2 +Pinocytosis 0.7936503713880352 2.14378824535044 0.0320498576139933 1.0 0.1968506357949172 8 Q9BZG1,Q06481,P50897 3 +Cytokine production involved in immune response 0.6678956351023981 2.143723210973404 0.0320550712648184 1.0 0.1968506357949172 15 Q7Z434,P30511,P14174,Q01650,P04439,Q9NY93,Q9H2U1,Q9NRA0 8 +Lysosomal lumen acidification 0.9068414571358826 2.1422991057556615 0.0321694207612373 1.0 0.1970081346802611 5 O75503,Q9NWW5,P50897 3 +Fibroblast proliferation 0.6852913922046409 2.1407580046875534 0.0322935581771728 1.0 0.1974054845270665 14 Q71SY5,Q13049,P14174 3 +Glycolipid biosynthetic process 0.7134916566690216 2.1389517250218995 0.0324395782778628 1.0 0.1977538060982616 12 Q8NBX0,Q16739,O60512,Q969N2,Q99805 5 +Regulation of b cell proliferation 0.7920818491647452 2.136965308901399 0.0326008133336213 1.0 0.1977641006488204 8 P00813,P02786,P14174 3 +Photoreceptor cell outer segment organization 0.8621257896182362 2.134429976818518 0.0328075999239585 1.0 0.1977641006488204 2 Q15555 1 +Positive regulation of endothelial cell chemotaxis 0.8618511397967588 2.13325577728295 0.0329037497908464 1.0 0.1978445120469471 2 Q9NWH9 1 +Regulation of endothelial cell chemotaxis 0.8618511397967588 2.13325577728295 0.0329037497908464 1.0 0.1978445120469471 2 Q9NWH9 1 +Lipopolysaccharide mediated signaling pathway 0.760442722553522 2.124458186213227 0.033631848941064 1.0 0.1997228248612388 9 Q8WTV0 1 +Regulation of cell activation 0.4397265461938883 2.123586785402633 0.033704711509473 1.0 0.1999772865428487 77 Q9HCL2,P30511,P14174,Q9Y6D9,P22466,P02786,P80404,P30825,P00813,P23396,Q15046,Q8WXW3,P12956,P04439,O96028,Q9NPF0,P11274,Q9NRA0,P31749,Q9NUQ9,P51809,Q9NQT5,O95219 23 +I kappab kinase nf kappab signaling 0.4625123745025759 2.119760542139975 0.0340262444331689 1.0 0.201168470859099 58 P14373,P42224,Q9NY93,P19474,Q8WVQ1,P09601,P02786,Q7Z434,Q8IUD2,Q8TB61,O75116,O43657,P32929,Q13049,O94874,Q13464,O60858,Q9NRA0,P31749,P35222,Q13325,Q5T9L3,Q96HY6,O60826,Q9H2U1 25 +Appendage morphogenesis 0.643619704938954 2.111498577700277 0.0347294800394806 1.0 0.204058664464779 16 O94788,P42892,Q9NX62 3 +Neurofilament cytoskeleton organization 0.856083493545726 2.108568652984202 0.0349818310357497 1.0 0.2051795248161974 2 P07196 1 +Phosphatidylethanolamine metabolic process 0.8977361108219384 2.1069350080407716 0.0351232135521724 1.0 0.2058275918189311 5 P35790,Q8NCC3 2 +Endocrine process 0.8113367998557444 2.1056889120484428 0.03523138360694 1.0 0.2058579769675912 7 P42892,O75787,P22466 3 +Regulation of leukocyte mediated immunity 0.5161487191511107 2.1056636149887935 0.0352335825142366 1.0 0.2058579769675912 37 Q9NUQ9,Q96FV9,Q9BY67,P51809,P02786,Q7Z434,P30511,Q9NQT5,O15400,O95219,P04439,O96028,Q9NY93,Q9H2U1,P11274,Q9NRA0 16 +Actin filament based movement 0.5828936146074886 2.1052235208755485 0.0352718557544853 1.0 0.2058579769675912 25 P35579,P35580,Q9UH99,Q7Z406,P16615,Q13464,Q9UM22,P09493 8 +Mitochondrial calcium ion transmembrane transport 0.7172078480027247 2.1050968655734015 0.0352828770369186 1.0 0.2058579769675912 11 P21796,Q9H4I9,Q8IYU8,Q9NWR8 4 +Lipid export from cell 0.8966203508991651 2.1025927643939912 0.0355013829722739 1.0 0.2062299169522763 5 P14174 1 +Glycerolipid biosynthetic process 0.4672621958478469 2.0996397342354585 0.0357605446838935 1.0 0.2068027171150655 52 Q96N66,O15228,Q9HCL2,Q9NX62,Q8WTV0,P17655,Q8WUK0,Q96PE3,Q92604,Q9NPH0,P35790,Q9Y6K0,Q14457,Q969N2,Q5H8A4,Q8NCC3,Q9BXW7 17 +Diacylglycerol metabolic process 0.957886816378022 2.099466454226735 0.0357758019504865 1.0 0.2068027171150655 3 Q9HCL2 1 +Azole transmembrane transport 0.8527876956879942 2.0944370596539987 0.0362210643565594 1.0 0.2078286452435937 2 P30825 1 +Protein trimerization 0.932259395490036 2.0923337664252 0.0364086691573075 1.0 0.2082325859185753 4 Q99720 1 +Regulation of signal transduction by p53 class mediator 0.508530398465373 2.091322873606232 0.0364991307281921 1.0 0.2084527586330213 39 Q8N2F6,Q9UNS2,Q7LG56,P14174,Q93009,O75844 6 +Viral transcription 0.5965851121232844 2.0897139676701983 0.0366435015385224 1.0 0.2086040383604967 20 P19474,Q01664,O60858,Q13573,Q13049 5 +Response to estradiol 0.6209327438869497 2.089514176791383 0.0366614631427497 1.0 0.2086040383604967 17 O94788,O95831 2 +Rho protein signal transduction 0.574946004816124 2.088787810423973 0.036726828166484 1.0 0.208719672484717 26 P84095,Q07960,Q13464,Q9NWH9,O75116,P57105,Q9UBT7,O75955,P41440,P11274 10 +Transition metal ion transport 0.6012808615691737 2.087851854644402 0.0368112002969964 1.0 0.208719672484717 18 Q8N4V1,O15173,Q9HC07,Q07960,Q9HD20,O75027 6 +Neutral lipid biosynthetic process 0.7806343561161381 2.087016163105662 0.0368866735211625 1.0 0.208719672484717 8 Q8WTV0,Q9HCL2 2 +Positive regulation of leukocyte proliferation 0.6009758421647222 2.0859912558285494 0.036979415141946 1.0 0.208719672484717 18 Q9HCL2,P30825,P14174 3 +Protein complex oligomerization 0.4406177691146297 2.085961470347085 0.0369821133315455 1.0 0.208719672484717 69 Q99720,Q9BUB7,Q06481,Q08379,O94788,Q4G0X4,P14174,Q9H1P3,Q15070,P31350,Q14168,Q9H9S5,Q9H223,Q9BPX6,Q96RR1,P32929 16 +Regulation of response to extracellular stimulus 0.851726584007014 2.084296562871574 0.0371331998067947 1.0 0.209144979131592 6 Q9UMX5,Q13573 2 +Protein kinase a signaling 0.7510852211857962 2.081828854078434 0.0373581051812785 1.0 0.2102339990057932 9 P14174 1 +Pigment biosynthetic process 0.5671198612777 2.0744189755106133 0.0380404165236494 1.0 0.2130349855870679 27 P22830,P00813,O75027 3 +Regulation of viral transcription 0.7777391430756653 2.0743408000183177 0.0380476711464221 1.0 0.2130349855870679 8 O60858,Q13049,P19474 3 +Cell morphogenesis involved in differentiation 0.3871412486024098 2.073755719630438 0.0381020034986803 1.0 0.2131600749888387 135 P07942,P84095,Q96N67,Q9UQB8,P05067,P35579,Q06481,Q8N0X7,P42892,O75592,P33176,P12814,Q96TA1,Q13464,O43707,Q13641,Q9Y4G8,Q7L576,P41440,Q14185,Q9NWH9,O75955,P07196 23 +Vascular transport 0.6367654436038898 2.0727593200449665 0.0381946840621594 1.0 0.2134993120018189 16 P11166,P02786,P53985,Q01650,P30825,P41440 6 +Liposaccharide metabolic process 0.5876010570490252 2.06951073308248 0.038498185195503 1.0 0.2148353500482721 22 P16278,P04066,Q8NBX0,Q16739,O60512,Q9NWW5,Q969N2,P06280 8 +Neuron development 0.3987174613802876 2.067698340445878 0.0386683980742157 1.0 0.215183523350208 209 Q14012,P07942,Q14108,P84095,Q96N67,O14976,Q8N3R9,P54802,Q12834,O75503,Q9NY93,Q9UQB8,Q96G23,P05067,Q9NR77,Q06481,Q8N0X7,Q8NHS3,P42892,O75592,Q13049,Q14457,P33176,Q9NZM3,O15078,P50897,Q96TA1,Q16739,Q13464,Q13641,Q9Y4G8,Q96F07,Q7L576,P41440,Q9Y6M7,Q15555,P08670,Q13555,O75955,P10586,Q9NQX7,P07196 42 +Intrinsic apoptotic signaling pathway in response to dna damage 0.5661010686820968 2.0674713777912914 0.0386897585132146 1.0 0.215183523350208 27 P46379,Q13573,P14174 3 +Iron ion transport 0.7090825811106591 2.0654691838584847 0.0388786283923086 1.0 0.2160536288389926 11 Q8N4V1,Q07960,O75027,O15173 4 +Regulation of endothelial cell migration 0.5404757809922079 2.0649944917463796 0.0389235214791459 1.0 0.2161228530129576 31 P42785,Q8WTV0,P25705,O75116,P57105,P78536 6 +Regulation of t cell apoptotic process 0.8862769120946812 2.062248428026923 0.0391840902174056 1.0 0.217027093199147 5 Q9HCL2 1 +Chemical homeostasis 0.3965316855900086 2.0608228514790614 0.0393199435587536 1.0 0.2173052942901217 204 P42785,Q9HCL2,O15118,Q8WTV0,P30519,Q7L0J3,O75027,O75503,P05067,O95563,Q9NWR8,Q06481,Q9Y487,P53985,P16615,O75787,Q6P4Q7,Q9HD20,Q9BPX6,Q96RR1,Q96CP7,P50897,Q16739,Q93050,O15254,Q9Y6M7,P61916,O15260,Q9H4I9,Q9NWW5,O60826,Q8IYU8 32 +Epithelial cell proliferation 0.4620272342907368 2.059223852119819 0.0394727992374981 1.0 0.2178037331198681 53 P07942,Q8WTV0,O94788,Q86VI3,P25705,P15291,P57105,Q9H2J4,Q9Y366,P78536 10 +Embryonic digit morphogenesis 0.7992511101069639 2.054635461481489 0.039914227840879 1.0 0.218786844673905 7 P42892,Q9NX62 2 +Peptidyl tyrosine modification 0.4876150209115602 2.0541939243618335 0.039956926217489 1.0 0.218786844673905 44 Q8WXW3,Q9NWH9,P14174,Q15375,P11274,O95684,Q9H2J4,P78536,Q9H223,P05067,Q9UIG0 11 +Regulation of cellular response to transforming growth factor beta stimulus 0.5952174632356999 2.0507965657302525 0.040286762151962 1.0 0.2191984588566076 18 Q92896,Q8N3R9,Q13573 3 +Negative regulation of ire1 mediated unfolded protein response 0.8426256522933253 2.0507530933703633 0.040290997626097 1.0 0.2191984588566076 2 Q96HY6 1 +Negative regulation of immune system process 0.4600810179233388 2.050266667526446 0.0403384154294494 1.0 0.2191984588566076 54 P19474,Q9HCL2,P22466,P30511,P14174,P00813 6 +Axon development 0.431100035900967 2.04833466558771 0.0405272185066414 1.0 0.2191984588566076 86 Q9UQB8,Q06481,O75592,P84095,Q96TA1,Q8N0X7,Q96N67,Q13049,P42892,P07196,P10586,O75955,Q7L576,P41440,Q96G23,P05067,P33176 17 +Cellular response to lipid 0.4179323768655082 2.0473755157062956 0.0406212284808815 1.0 0.2191984588566076 108 O15118,O15173,Q8WTV0,O94788,P08670,Q01664,O95831,P14174,P25705,O75116,Q9P1Z2,Q9NS86,Q13573,P11274,Q9NRA0 15 +Positive regulation of leukocyte mediated immunity 0.5738618213815917 2.0455965860345757 0.0407960776381808 1.0 0.2199225447436884 25 Q9NUQ9,Q9BY67,P02786,Q7Z434,P30511,O15400,P04439,O96028,Q9NY93,Q9H2U1 10 +Regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6824483156461664 2.037602869067985 0.0415896648895472 1.0 0.2223205962733624 13 P23396,Q13049,P14174 3 +Positive regulation of heart rate 0.9414835164835168 2.03759695451709 0.0415902568695139 1.0 0.2223205962733624 3 P00813,P16615 2 +Endothelial cell migration 0.5017819483526144 2.036237522158512 0.0417265101458996 1.0 0.2223205962733624 39 P35579,P42785,Q8WTV0,O75116,P25705,P57105,P78536 7 +Monocarboxylic acid transport 0.7689629722649856 2.0358140334739896 0.0417690327153843 1.0 0.2223205962733624 8 P53985,P14174 2 +Phosphatidylinositol acyl chain remodeling 0.8387805547926381 2.034180619603534 0.0419333878332566 1.0 0.2223205962733624 2 Q96N66 1 +Regulation of b cell apoptotic process 0.8789544317960629 2.0335893661100073 0.0419930148909659 1.0 0.2223205962733624 5 P14174 1 +Negative regulation of b cell apoptotic process 0.8789544317960629 2.0335893661100073 0.0419930148909659 1.0 0.2223205962733624 5 P14174 1 +Regulation of mitochondrial gene expression 0.6812737193077603 2.0315672371122635 0.0421974862883121 1.0 0.2225130180453275 13 Q567V2,Q9Y2R0,Q9BRT2,Q9NWS8 4 +Regulation of long term synaptic potentiation 0.7937009309817136 2.031097747043738 0.0422450799680833 1.0 0.2225130180453275 7 Q99538,Q92542,P05067 3 +Nerve growth factor signaling pathway 0.9395720226194536 2.0303645784077564 0.0423194944020421 1.0 0.2227289030022173 3 Q9Y4G8 1 +Regulation of lipid localization 0.5483132130346762 2.0273904700666407 0.0426224957782699 1.0 0.2241465583035616 29 Q8WTV0,P22466,P14174 3 +Positive regulation of lipid transport 0.738921593736228 2.026122590629447 0.0427522236404245 1.0 0.2246514717004326 9 P14174 1 +Phosphatidylcholine metabolic process 0.6459289021473292 2.0237722651975796 0.0429935891440766 1.0 0.2253865338056514 15 Q8WTV0,P35790,Q8NCC3 3 +Synapse organization 0.4303204205660655 2.01955824458087 0.0434292300165473 1.0 0.2264625331744467 71 Q14012,Q9BQT9,Q16352,Q13136,Q12834,Q9UQB8,P05067,Q8IUD2,Q14203,Q15375,Q9Y6W5,P12814,Q9Y4W6,Q13641,Q7L576,Q9BRK5,P49354,P10586,Q99538,Q9H2U1,P07196 21 +Negative regulation of signal transduction by p53 class mediator 0.7374771890115908 2.0194857414294924 0.0434367578263459 1.0 0.2264625331744467 9 Q8N2F6,P14174 2 +Modulation of excitatory postsynaptic potential 0.9129719283988827 2.0189788470275527 0.0434894181264511 1.0 0.2265598068620358 4 Q9UQB8 1 +Response to retinoic acid 0.6787375385073763 2.0185220630108067 0.0435369187406942 1.0 0.226630069975973 13 O94788,Q13573 2 +Signal release 0.4380092013695758 2.017196524486736 0.04367500863715 1.0 0.2271714149487357 67 O95563,P22466,Q4J6C6,Q96TA1,P50897,P51809,Q13555,P80404,P16615,P53985,P14174,Q7L0J3,O95219,Q9BRT2,O14523,O14936 16 +Inflammatory response 0.4295113713761665 2.012861417720755 0.0441292104787633 1.0 0.2281528100525403 79 P42785,P22466,Q06481,Q8IV08,P28070,P14174,P15291,O95219,P00813,P05067 10 +Regulation of i kappab phosphorylation 0.8338368580060413 2.012838639472091 0.0441316075126758 1.0 0.2281528100525403 2 Q96HY6 1 +Mammary gland epithelial cell differentiation 0.8338368580060412 2.012838639472091 0.0441316075126758 1.0 0.2281528100525403 2 P31751 1 +Positive regulation of glycogen metabolic process 0.8338368580060412 2.012838639472091 0.0441316075126758 1.0 0.2281528100525403 2 P31751 1 +Positive regulation of i kappab phosphorylation 0.8338368580060413 2.012838639472091 0.0441316075126758 1.0 0.2281528100525403 2 Q96HY6 1 +Positive regulation of myeloid leukocyte cytokine production involved in immune response 0.7892069232411058 2.0119970034659183 0.0442202528661932 1.0 0.2282258286967045 7 Q9NY93,Q7Z434,P14174 3 +Calcium import into the mitochondrion 0.7629166150227129 2.009180273342823 0.0445180189656144 1.0 0.2290565329392396 8 P21796,Q9H4I9,Q8IYU8,Q9NWR8 4 +Aminoglycan catabolic process 0.872732270478278 2.009173690680246 0.044518716817697 1.0 0.2290565329392396 5 P16278,P04066,P15586,P54802 4 +Glycosaminoglycan catabolic process 0.872732270478278 2.009173690680246 0.044518716817697 1.0 0.2290565329392396 5 P16278,P04066,P15586,P54802 4 +Phosphatidic acid metabolic process 0.7879271924325028 2.0065509383604665 0.0447974997694347 1.0 0.2301265876006316 7 Q9HCL2 1 +Regulation of toll like receptor 4 signaling pathway 0.932967032967033 2.0053379073266338 0.0449269348972296 1.0 0.230267820938647 3 P41440,Q06481 2 +Toll like receptor 4 signaling pathway 0.932967032967033 2.0053379073266338 0.0449269348972296 1.0 0.230267820938647 3 P41440,Q06481 2 +Lysosomal transport 0.4577865321898907 2.0022127632146387 0.0452618535765794 1.0 0.2316280571280711 51 P11717,Q14108,Q8WUH2,O15118,P20645,Q9HD42,P07602,Q8IWJ2,Q99523,Q96ED9,O14976 11 +Cell cell adhesion 0.4054295728927507 1.9996747000588655 0.0455354018413278 1.0 0.2326705387030426 117 P07942,P26038,Q9HCL2,Q9BQT9,O00192,Q9UQB8,Q9Y6D9,P35579,P35221,Q9BY67,Q96JJ3,P02786,P80404,Q96GC9,Q15375,P30825,P00813,P23396,P12814,Q13464,Q14168,Q96F07,P04439,Q9BX67,P41440,Q9BZE4,Q9NUQ9,P57105,O75955,P10586 30 +Regulation of phagocytosis 0.5838317034215621 1.994637381468847 0.0460824434547595 1.0 0.2348665371054972 19 Q8WTV0 1 +Neuron projection guidance 0.555423382063349 1.9943675303476824 0.0461119042097073 1.0 0.2348665371054972 27 Q96TA1,P84095,P42892,Q7L576,O75592,P05067,P33176 7 +Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator 0.8294808750293832 1.9942128086877835 0.0461288029616602 1.0 0.2348665371054972 6 Q8N2F6,P14174 2 +Lipid homeostasis 0.5421247131866207 1.983452161526558 0.0473169455972426 1.0 0.2389438419978224 29 Q8WTV0,O15254,Q9HCL2,Q96CP7 4 +Peptide catabolic process 0.701807603093549 1.9833639672246253 0.0473267889583666 1.0 0.2389438419978224 10 Q9UIQ6,Q9NZ08,P42892,P55786 4 +Long term synaptic potentiation 0.6910076233674333 1.976710857981203 0.0480743227690394 1.0 0.2415680336426167 11 Q99538,Q14168,Q92542,P05067 4 +Regulation of organic acid transport 0.6699912501200862 1.973397985785973 0.048450236926991 1.0 0.2424783874599152 13 Q7L0J3,P31751,P80404,P14174 4 +Natural killer cell activation 0.6992145320355888 1.9708516730056032 0.048740844229471 1.0 0.2432593203944595 10 Q8WXW3,P46379,P30511,P51809 4 +Photoreceptor cell maintenance 0.8628367234744316 1.9702257506126044 0.048812503582079 1.0 0.2432593203944595 5 P11166,Q15555,Q15051,P51790 4 +Retina homeostasis 0.8628367234744316 1.9702257506126044 0.048812503582079 1.0 0.2432593203944595 5 P11166,Q15555,Q15051,P51790 4 +Plasma membrane raft organization 0.9230594554072344 1.9676945263271464 0.0491031960141863 1.0 0.2436244282151405 3 P41440 1 +Plasma membrane raft assembly 0.9230594554072344 1.9676945263271464 0.0491031960141863 1.0 0.2436244282151405 3 P41440 1 +Cellular response to copper ion 0.923017620632729 1.9675353180557904 0.0491215283711237 1.0 0.2436244282151405 3 P05067 1 +Circulatory system process 0.4246585305515287 1.9658404459473868 0.0493170441218795 1.0 0.243881352303175 83 P42785,Q01650,P10253,P11166,Q9HB40,Q9UIQ6,P02786,P53985,P16615,O75787,P80404,O75116,P42892,P30825,P00813,Q13464,P09493,P41440,P11274,Q9NZ08,O75844 21 +Protein demannosylation 0.8616745868928877 1.965642281434059 0.0493399464062254 1.0 0.243881352303175 5 O60858 1 +Positive regulation of cell cell adhesion 0.5331462124159279 1.9636330135075553 0.0495726660083537 1.0 0.2448500175045671 30 P00813,P41440,Q9HCL2,P30825 4 +Regulation of peptidyl tyrosine phosphorylation 0.5056672295162177 1.9626813678967625 0.0496832094283878 1.0 0.2452142403121099 34 Q8WXW3,P14174,Q15375,O95684,Q9H2J4,P78536,Q9H223,P05067 8 +Protein lipid complex subunit organization 0.8212755986747435 1.960780236132182 0.0499046645283383 1.0 0.246124929498385 6 Q8WTV0 1 +Hormone mediated signaling pathway 0.4658985030707728 1.959696065173747 0.0500313253557023 1.0 0.2465671012167489 47 Q9NS86,Q9P1Z2,P42785,Q06481 4 +Regulation of cell aging 0.666939211101327 1.9576023733668817 0.0502766886594898 1.0 0.2475931829550487 13 O75844,P14174 2 +Cyclic nucleotide mediated signaling 0.8586795174385512 1.953820683904361 0.0507224272567992 1.0 0.2494629713170622 5 P22466 1 +Camp mediated signaling 0.895930336071206 1.9537461029941383 0.0507312511083024 1.0 0.2494629713170622 4 P22466 1 +Negative regulation of t cell apoptotic process 0.919298365727476 1.9533725448174568 0.0507754670502245 1.0 0.2494962661914792 3 Q9HCL2 1 +Positive regulation of blood circulation 0.8582356256139283 1.9520675296013643 0.0509301876726553 1.0 0.2500721005621978 5 P00813,P16615 2 +Regulation of cell cell adhesion mediated by cadherin 0.8578952803477372 1.9507231406056185 0.0510899890883482 1.0 0.2504875623956324 5 P41440 1 +B cell activation involved in immune response 0.5786120831015799 1.9485789500013768 0.0513457279888773 1.0 0.2512340521450711 18 P00813,Q9UQ84 2 +Protein localization to chromosome centromeric region 0.6651295446838965 1.948224571860843 0.0513880979008736 1.0 0.2512340521450711 13 Q8IY18,Q96DY7 2 +Spindle assembly 0.4450744158495562 1.9481830171855783 0.0513930681485415 1.0 0.2512340521450711 58 Q9HD42,Q8N3U4,Q8WVM7,Q9H6D7,Q12834,Q96CW5,Q08379,P12270,P23396,Q8WXW3,Q9NZZ3,P52732,O95239,Q9UQE7,Q15691,Q15555,O94927,Q96CS2,Q9BSJ2,O43663 20 +Germinal center formation 0.9172624308127136 1.9456126069448425 0.0517012914922563 1.0 0.2525555023555014 3 P00813 1 +Positive regulation of dna binding transcription factor activity 0.460445265750684 1.944914727011099 0.0517852422500402 1.0 0.2525835171685109 48 P19474,P02786,Q7Z434,O60858,P14373,P05067,O75955,Q96HY6,P41440,P32929,Q13049,P60900 12 +Purine nucleoside biosynthetic process 0.8173330240272477 1.9446774658536168 0.0518138093067404 1.0 0.2525835171685109 6 P00813,Q13126 2 +Response to copper ion 0.721079227957842 1.9438181192984336 0.0519173879615886 1.0 0.2526848473251022 9 O75592,P05067,Q14457,Q00796 4 +Regulation of neuron projection development 0.4232894527696075 1.9408077199961964 0.0522816042765041 1.0 0.2540863087486122 76 Q9NR77,Q14012,Q14108,Q9NQX7,Q8N0X7,Q7L576,P08670,Q13555,Q9Y4G8,O14976,Q12834,P10586,Q9NY93,Q9UQB8,Q96G23,P07196 16 +Ammonium transmembrane transport 0.8170832188959074 1.94023066607398 0.052351663226561 1.0 0.254152838603439 2 P55011 1 +Cellular response to reactive oxygen species 0.5001476658675699 1.9374616091643608 0.0526889418725979 1.0 0.2555068556747601 35 P23396,Q99720,Q9NWH9,O95831,P39210,P09493,Q14457 7 +Positive regulation of synaptic transmission 0.5696104858135088 1.9363964791604196 0.0528191603788117 1.0 0.2559520477120164 21 Q9BQT9,Q14168,O75955,P41440,Q92542,P05067 6 +Organic hydroxy compound catabolic process 0.6127879078855143 1.9359904262380176 0.0528688735357378 1.0 0.2560067618958005 16 Q8WTV0,P30837,Q00796 3 +Neural precursor cell proliferation 0.5466654659269117 1.93401925170361 0.0531107608762404 1.0 0.2569912851985403 27 Q9NZI8,P35221,Q06481,O75306,Q96N67,Q86VS8,P48681,Q9NXR1,O95456,P35222 10 +Myeloid leukocyte cytokine production 0.7455279237083562 1.932177943272672 0.0533375466041623 1.0 0.2579013592333335 8 Q9NY93,Q7Z434,Q9H2U1,P14174 4 +Heme transport 0.9132431477604354 1.930278375561177 0.0535723549366431 1.0 0.2582869760802121 3 O75027 1 +Iron coordination entity transport 0.9132431477604354 1.930278375561177 0.0535723549366431 1.0 0.2582869760802121 3 O75027 1 +Positive regulation of b cell proliferation 0.8134079264308683 1.9286213908214815 0.053777881510912 1.0 0.258729613214905 6 P00813,P02786,P14174 3 +Activated t cell proliferation 0.8131694743232354 1.9276451848810188 0.0538992745254547 1.0 0.258729613214905 6 Q9HCL2,Q9BY67 2 +Response to ischemia 0.6898458605750384 1.9255110314531645 0.0541654572173448 1.0 0.258729613214905 10 O95831 1 +Triglyceride metabolic process 0.6281236378885972 1.9254282441004025 0.0541758049485705 1.0 0.258729613214905 15 Q9HCL2 1 +Negative regulation of cytokine production involved in immune response 0.8132381213952169 1.9235065433331704 0.0544164655330852 1.0 0.258729613214905 2 P30511 1 +Purine containing compound salvage 0.7165251271067214 1.9226998772842268 0.0545177522732989 1.0 0.258729613214905 9 P00813,Q13126 2 +Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.6273876040192393 1.921341763054093 0.0546886352984286 1.0 0.2589839211040723 15 P78536,Q13573 2 +Leukocyte proliferation 0.4722510165322428 1.920613686960389 0.0547804283463302 1.0 0.2591664038740959 44 P30825,Q9HCL2,P22466,P14174 4 +Neuron differentiation 0.4007887669981498 1.9192204874371592 0.0549564357833629 1.0 0.2595143385007423 247 Q14012,P07942,Q14108,O94788,P84095,Q96N67,O14976,Q8N3R9,P54802,Q12834,O75503,Q9NY93,Q9UQB8,Q96G23,P05067,Q9NR77,Q06481,Q8N0X7,Q8WUJ1,Q15375,Q8NHS3,P42892,O75592,Q969N2,Q13049,Q14457,P33176,Q9NZM3,O15078,P50897,Q96TA1,Q9P2X3,Q16739,Q13464,Q13641,Q9Y4G8,Q96F07,Q7L576,P41440,Q9Y6M7,Q15555,P08670,Q13555,Q9NWH9,O75955,P10586,Q9NQX7,P07196 48 +Vascular process in circulatory system 0.492567837083161 1.9162383261838547 0.055334767046794 1.0 0.2605622281503808 37 P11166,Q9HB40,P02786,P53985,Q13464,Q01650,O75116,P42892,P30825,P41440,P11274 11 +Angiotensin activated signaling pathway 0.9093406593406596 1.915371114556429 0.0554451921957417 1.0 0.2608666908093133 3 O75116,O43865 2 +Double strand break repair via nonhomologous end joining 0.5606771849637534 1.9151158736864504 0.0554777278818545 1.0 0.2608666908093133 23 O96028,Q9Y2K7,P12956 3 +Regulation of epithelial cell migration 0.4563027414781816 1.9068691258598007 0.0565375371059839 1.0 0.2651017661767567 48 Q15555,P42785,Q8WTV0,O75116,P25705,P57105,P78536,Q14185 8 +Protein o linked mannosylation 0.8464830620450141 1.905548061154946 0.0567088662496075 1.0 0.2655059668656584 5 Q6ZXV5,Q9H9S5,O43505 3 +Protein mannosylation 0.8464830620450141 1.905548061154946 0.0567088662496075 1.0 0.2655059668656584 5 Q6ZXV5,Q9H9S5,O43505 3 +Smad protein signal transduction 0.7126422455649994 1.9046591614820776 0.0568243908184074 1.0 0.265698888437227 9 Q9UIQ6,Q01082,P08670,Q8N1F7 4 +Maintenance of dna repeat elements 0.883009518017291 1.9040329488016656 0.0569058931639805 1.0 0.2657070540655937 4 O75844 1 +Ribonucleoside metabolic process 0.7119427133158367 1.9014055729367785 0.0572489101491084 1.0 0.2671214904226259 9 P00813,Q13126 2 +Regulation of attachment of spindle microtubules to kinetochore 0.7629230133614695 1.89954123444577 0.057493350427564 1.0 0.2679696645171868 7 Q14457 1 +Positive regulation of mitochondrial translation 0.7113443700657054 1.8986218007741764 0.0576142199141305 1.0 0.2682624369586664 9 Q567V2,Q9Y2R0,Q9NWS8 3 +Regulation of amyloid beta clearance 0.8053644026436678 1.8956422724842903 0.0580073634991973 1.0 0.2689672372873763 6 Q16850,Q13464 2 +Vacuolar localization 0.5700148146438666 1.89523899073198 0.0580607467224796 1.0 0.2689672372873763 18 P35579,P51809,Q8NCA5,O95219,Q9BZG1,Q9NRA0,P33176 7 +Iron ion transmembrane transport 0.8805174761784026 1.8944201688340951 0.0581692614334548 1.0 0.2689672372873763 4 O75027 1 +Carbohydrate transmembrane transport 0.5877887531042023 1.8930891437066764 0.0583460156545143 1.0 0.2694431897884409 17 P11166,Q06481,Q99523,P31751,O75298,Q16625 6 +Folic acid transport 0.8058225762153205 1.8911915816353 0.058598774708551 1.0 0.269457305647395 2 P41440 1 +Folate transmembrane transport 0.8058225762153205 1.8911915816353 0.058598774708551 1.0 0.269457305647395 2 P41440 1 +Regulation of cellular response to growth factor stimulus 0.4840513606031847 1.890177503122797 0.0587342244077719 1.0 0.2698938877441274 39 Q8N0X7,Q92896,Q96TA1,Q96F07,Q8N3R9,Q13573,P78536,Q7L576 8 +B cell activation 0.4686909891955484 1.889438302036747 0.0588331226772838 1.0 0.2701620237069207 44 P00813,Q9UQ84,O96028,P14174 4 +Positive regulation of multicellular organismal process 0.3919964569386312 1.8854338728101996 0.0593712844466332 1.0 0.2715359500586817 224 Q9HCL2,Q9BQT9,Q86VI3,P30511,P14174,Q01650,P14373,Q9NY93,Q9UQB8,P05067,P22466,Q06481,Q9BY67,P02786,Q7Z434,P16615,O75787,P80404,O75116,Q9H2J4,P00813,Q13049,Q14457,P23396,P23786,Q96TA1,Q8WXW3,Q13464,Q13641,P30533,P12956,Q13573,P09493,O96028,P78536,P41440,Q7L576,Q9NRA0,Q9NUQ9,P51809,Q9NZ08,Q01082,O95219,O75955,Q96RK4,Q9H2U1,P07196 47 +Regulation of cell junction assembly 0.4887477485455547 1.885244667297679 0.0593968128160955 1.0 0.2715359500586817 37 Q9BQT9,Q13464,O75116,Q13641,Q9Y4G8,O75955,P41440,P05067 8 +Odontogenesis 0.6814376633945478 1.8846418288330444 0.0594782109572218 1.0 0.2715359500586817 10 P07942,P35221,Q6P4Q7,O75592,P35222 5 +Regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.515932888184828 1.8838352774334144 0.0595872601271942 1.0 0.2715359500586817 31 Q92896,Q8N3R9,Q13573,Q8N1F7,P78536 5 +Hormone metabolic process 0.495519293199362 1.8828968294979365 0.059714350988413 1.0 0.2715359500586817 34 Q9HB40,P22466,O94788,O75787,P42892,Q9UBM7,O75844 7 +Vacuole organization 0.4270540260269568 1.8828681774483969 0.0597182347740758 1.0 0.2715359500586817 66 Q14108,P50897,Q9HC07,P16615,O75787,Q96ED9,P10253,O14773,P54802,Q8NHS3,O75503,P11117,O95219,Q9NWW5,Q14457 15 +Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage 0.6809117898321132 1.8820802534364136 0.0598251200189321 1.0 0.2715359500586817 10 P14174 1 +Positive regulation of syncytium formation by plasma membrane fusion 0.8016281564326582 1.8802889428404328 0.0600687094255532 1.0 0.272085527465983 6 Q14012,P41440,O75955 3 +Regulation of syncytium formation by plasma membrane fusion 0.8016281564326582 1.8802889428404328 0.0600687094255532 1.0 0.272085527465983 6 Q14012,P41440,O75955 3 +Regulation of cell population proliferation 0.3990359763219309 1.87881988828902 0.0602690904717975 1.0 0.2725230996603601 250 Q9BSK2,P07942,Q9HCL2,P98175,O94788,Q86VI3,P84095,P14174,Q71SY5,P02545,Q12834,Q9Y366,Q96G23,P05067,Q9NR77,P22466,Q06481,Q15392,P30825,Q9H2J4,P00813,Q96DY7,Q13049,Q14457,P43490,Q96TA1,Q01664,Q13641,Q9Y4G8,P12956,P52756,P09493,P78536,Q9NRA0,O75569,Q8NCA5,P25705,P15291,P57105,P31751,O95684,O43663,Q96HY6,O75844 44 +Positive regulation of erk1 and erk2 cascade 0.5625008578376093 1.8751667679436457 0.0607697844256878 1.0 0.273630568379881 20 P05067,P14174 2 +Regulation of modification of synaptic structure 0.8985790833131968 1.8741691990231344 0.0609071079958476 1.0 0.2736507488714314 3 Q9UQB8 1 +Regulation of modification of postsynaptic structure 0.8985790833131968 1.8741691990231344 0.0609071079958476 1.0 0.2736507488714314 3 Q9UQB8 1 +Purine ribonucleoside metabolic process 0.7306300951080813 1.8657364364869944 0.0620782492403537 1.0 0.2775434069853842 8 P00813,Q13126 2 +Leucine transport 0.7997802801428131 1.8648024869602189 0.0622090945851834 1.0 0.2775434069853842 2 Q01650 1 +Tryptophan transport 0.7997802801428131 1.8648024869602189 0.0622090945851834 1.0 0.2775434069853842 2 Q01650 1 +Leucine import across plasma membrane 0.7997802801428131 1.8648024869602189 0.0622090945851834 1.0 0.2775434069853842 2 Q01650 1 +Response to l glutamate 0.8728102967182334 1.86464126318571 0.0622317049431433 1.0 0.2775434069853842 4 Q9UQB8 1 +Regulation of multicellular organism growth 0.5647055456102352 1.8621590990214496 0.0625806677235283 1.0 0.278540406841596 18 Q9HCL2,Q96RK4,Q99538,O75844,P05067 5 +Nucleobase containing small molecule biosynthetic process 0.7536611514108158 1.859619466716249 0.0629393831662363 1.0 0.279576740024422 7 P00813,Q13126 2 +Negative regulation of rna catabolic process 0.5061138854407464 1.858714702781679 0.0630675883104983 1.0 0.2799595875502 32 Q06787,A2RRP1,Q9NZI8,O60506,Q16539,P98175,Q99729,Q9H814,P35637,Q14103,Q92804,Q9H7Z3,Q9H2U1,P07910,Q9Y2W1,Q13151 16 +Tail anchored membrane protein insertion into er membrane 0.6670036115454376 1.8575753163114164 0.0632293464986408 1.0 0.2804907694543569 11 P46379,O43681 2 +Protein localization to microtubule end 0.7978577313924721 1.8563951936210343 0.0633972493183305 1.0 0.2808479252057071 2 Q15555 1 +Positive regulation of chromosome segregation 0.752706998426119 1.8554982382734495 0.0635251105699374 1.0 0.2808678246366911 7 Q8IY18 1 +Transposition rna mediated 0.7970337819280409 1.8527904977710152 0.0639123927313141 1.0 0.2815351169031279 2 Q9HCE1 1 +Activation of immune response 0.4419982922259345 1.8524543566849152 0.0639606060209099 1.0 0.2815351169031279 51 P00813,P46379,Q06481 3 +Glycoside catabolic process 0.7948252110291917 1.852278424526992 0.06398585224194 1.0 0.2815351169031279 6 Q9BTY2,P08236,P04066,P06280 4 +Cellular response to molecule of bacterial origin 0.5293573609460288 1.8514936316954809 0.0640985700648424 1.0 0.2815351169031279 28 Q8WTV0,Q9NUQ9,P14174 3 +Negative regulation of viral transcription 0.7943361705197061 1.85026212340883 0.0642757789693861 1.0 0.2816262648995389 6 O60858,Q13049,P19474 3 +Positive regulation of cell population proliferation 0.3688120396087602 1.8499452433515968 0.0643214420529416 1.0 0.2816262648995389 137 Q9BSK2,P07942,Q9HCL2,O94788,P84095,Q86VI3,P14174,Q12834,P02786,P30825,Q9H2J4,P00813,P23396,P43490,Q9NPF0,P78536,Q9NRA0,Q9Y5B6,Q8NCA5,P15291,P31751,O95684,O43663,Q96HY6,Q9UPN4 25 +Collateral sprouting 0.8689316290005179 1.8496271159751163 0.064367311812183 1.0 0.2816262648995389 4 P05067,Q8N0X7 2 +Alcohol catabolic process 0.6461972333282932 1.849588196595063 0.0643729253252285 1.0 0.2816262648995389 13 Q8WTV0,P30837,Q00796 3 +Ceramide metabolic process 0.5533314412443 1.8485354015726576 0.0645249279552178 1.0 0.2817363007638376 22 Q16739,Q8NCC3,O60512,Q9NWW5,Q9NRA0,Q99805,Q96G23,P06280 8 +Positive regulation of cell adhesion molecule production 0.890659340659341 1.8437620778450303 0.0652178215805241 1.0 0.2819898411362961 3 P41440,O75955 2 +Toll like receptor 3 signaling pathway 0.8295463358986954 1.8381684745683715 0.0660375836506368 1.0 0.2849795465441666 5 P41440,O75955 2 +Amyloid precursor protein metabolic process 0.5516580452671173 1.837624321079195 0.0661177824423153 1.0 0.2851409607852085 22 Q13464,Q15392,O75116,P78536,Q9NQX7,Q92542 6 +Clathrin dependent endocytosis 0.5541311128081157 1.8369751600212365 0.066213562487813 1.0 0.2853693187945009 21 Q9NZM3,O14976,O00291,Q5VW38,Q9NUN5 5 +Engulfment of apoptotic cell 0.888786659536195 1.8365617426678391 0.0662746194427441 1.0 0.2854478276321941 3 P84095 1 +B cell proliferation 0.6624744430441991 1.8349393551637525 0.0665146756228218 1.0 0.2858509643214287 11 P00813,P02786,P14174 3 +Positive regulation of lymphocyte mediated immunity 0.5583208208133605 1.8346442089704689 0.0665584237593481 1.0 0.2858509643214287 19 Q9NUQ9,Q9BY67,P02786,P30511,P04439,O96028,O15400 7 +Cellular response to camp 0.8276099501817447 1.8304400494459083 0.0671841636243297 1.0 0.2873222607374257 5 P05067 1 +Angiogenesis involved in wound healing 0.8869814952092487 1.8296173119859176 0.0673071831851286 1.0 0.2876637341645363 3 P42785 1 +Vitamin transmembrane transport 0.7890223385616748 1.8283300814393424 0.0675000277968589 1.0 0.2881183121143312 6 Q8WTV0 1 +Eye photoreceptor cell differentiation 0.7460377463598155 1.8266483218913576 0.0677526629603078 1.0 0.2888266111993159 7 P54802,Q15555,O15078 3 +Glycosphingolipid biosynthetic process 0.8623764901007288 1.8242109622031093 0.0681201849574497 1.0 0.2902076677567057 4 Q16739,O60512 2 +Nerve development 0.6950941130256383 1.8227317103186265 0.0683440350857318 1.0 0.2909752752563778 9 Q9Y4W6,Q9H061,P42892 3 +Calcium ion regulated exocytosis of neurotransmitter 0.7898928865696191 1.821510944592279 0.0685292245275241 1.0 0.2915774093402897 2 P16615 1 +Positive regulation of leukocyte cell cell adhesion 0.5463413396651906 1.8208011553890011 0.068637088621539 1.0 0.2916638529880833 23 P00813,Q9HCL2,P30825 3 +Cell cell adhesion mediated by cadherin 0.7444833200237733 1.819913267596943 0.068772214112502 1.0 0.2920517926268967 7 P41440 1 +Antigen processing and presentation of exogenous peptide antigen 0.7443767418805748 1.819451333592335 0.0688426011320022 1.0 0.2921644913009751 7 Q9UIQ6,Q99538,P30511 3 +Keratan sulfate metabolic process 0.8826923076923082 1.8131025045627136 0.0698160129662408 1.0 0.2954728555225161 3 P16278,O43505 2 +Immune response regulating cell surface receptor signaling pathway 0.5125269387387099 1.8130035382588163 0.069831275597608 1.0 0.2954728555225161 30 P46379,Q06481 2 +Regulation of mitochondrial atp synthesis coupled electron transport 0.7876956879978015 1.8118726827437144 0.0700058712137661 1.0 0.2954728555225161 2 Q9H3K2 1 +Negative regulation of blood pressure 0.7849705970294831 1.8115787882355316 0.0700513049297615 1.0 0.2954728555225161 6 P42785 1 +Positive regulation of interferon beta production 0.6577920069782606 1.8114863325108563 0.0700656028403985 1.0 0.2954728555225161 11 Q7Z434,P41440,O75955 3 +Positive regulation of cell cell adhesion mediated by cadherin 0.8582529892989077 1.8081966842546888 0.0705758945060577 1.0 0.297060761272181 4 P41440 1 +Cytokine production involved in inflammatory response 0.6916298124304165 1.806482915257297 0.0708429404357473 1.0 0.2971810569650185 9 Q06481 1 +Regulation of toll like receptor 3 signaling pathway 0.8576834774837494 1.805983319853346 0.0709209450679515 1.0 0.2971810569650185 4 P41440 1 +Dendrite extension 0.7835168143657788 1.8055624394745455 0.0709867141253233 1.0 0.2971810569650185 6 Q96F07,Q9NZM3 2 +Regulation of systemic arterial blood pressure 0.6910877590269867 1.8039383018736748 0.0712409796749695 1.0 0.2975795152365192 9 P42785,P42892,P09493 3 +Positive regulation of binding 0.4303830656972688 1.8017015745048304 0.0715923702422542 1.0 0.2975795152365192 58 P19474,Q96TA1,Q9NWH9,Q71SY5,Q9Y4G8,O75955,O75503,P41440,P05067,Q96D46 10 +Positive regulation of lymphocyte differentiation 0.6904039629757737 1.800727450590169 0.0717458487272 1.0 0.2976178535429148 9 P00813 1 +Syncytium formation 0.6902182550709363 1.7998552735974778 0.071883493547413 1.0 0.2976178535429148 9 P35579,Q14012,P41440,O75955 4 +Taxis 0.4105852341598122 1.799457944368705 0.0719462707464939 1.0 0.2976178535429148 79 Q92538,Q9NUQ9,P55011,Q96TA1,P84095,Q96JJ3,Q99538,Q9NWH9,Q9BX67,P14174,Q13641,Q15375,P42892,P78536,Q7L576,O75592,P05067,P33176 18 +Myelin assembly 0.7396875467889241 1.7991083879759404 0.0720015370622197 1.0 0.2976178535429148 7 Q9NR77 1 +Dna methylation involved in gamete generation 0.878846153846154 1.7982765328949972 0.0721331966448901 1.0 0.2976178535429148 3 Q8NB78,Q8N2A8 2 +Cytoplasm organization 0.8788461538461543 1.7982765328949972 0.0721331966448901 1.0 0.2976178535429148 3 Q8N2A8,P33176 2 +Regulation of calcium ion import 0.7815902385851978 1.7975847077402194 0.0722428434888207 1.0 0.2976178535429148 6 P14373,P21796,Q9NRA0 3 +Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 0.78439989014007 1.7974033933090954 0.0722716024362053 1.0 0.2976178535429148 2 P35222 1 +Mesenchymal to epithelial transition involved in metanephros morphogenesis 0.78439989014007 1.7974033933090954 0.0722716024362053 1.0 0.2976178535429148 2 P35222 1 +Metanephric renal vesicle morphogenesis 0.78439989014007 1.7974033933090954 0.0722716024362053 1.0 0.2976178535429148 2 P35222 1 +Positive regulation of mesenchymal cell proliferation 0.78439989014007 1.7974033933090954 0.0722716024362053 1.0 0.2976178535429148 2 P35222 1 +Metanephric nephron morphogenesis 0.78439989014007 1.7974033933090954 0.0722716024362053 1.0 0.2976178535429148 2 P35222 1 +Glycosylceramide biosynthetic process 0.8784725283048989 1.7968354529650814 0.0723617462162704 1.0 0.297670614809537 3 O60512 1 +Phosphatidylethanolamine biosynthetic process 0.8553112521690822 1.7967597739902184 0.0723737649694507 1.0 0.297670614809537 4 P35790 1 +Amyloid precursor protein biosynthetic process 0.8187393563967345 1.7949726821429268 0.0726580524837121 1.0 0.2984713956220555 5 Q9NQX7 1 +Positive regulation of protein serine threonine kinase activity 0.5040002489464187 1.7946754927755992 0.0727054173832886 1.0 0.2984819445624473 31 Q14012,P14174,Q9Y4G8,P78536,Q8NDZ4 5 +Negative regulation of response to food 0.8767134384101994 1.790048618818214 0.0734460957657283 1.0 0.3002278135503362 3 Q9UMX5 1 +Regulation of response to food 0.8767134384101994 1.790048618818214 0.0734460957657283 1.0 0.3002278135503362 3 Q9UMX5 1 +Regulation of appetite 0.8767134384101994 1.790048618818214 0.0734460957657283 1.0 0.3002278135503362 3 Q9UMX5 1 +Glycosyl compound biosynthetic process 0.7136914546140185 1.7896855232629745 0.0735044809772653 1.0 0.3002822542927769 8 P00813,Q13126 2 +Triglyceride biosynthetic process 0.7372992453453392 1.788733214334442 0.0736577911488847 1.0 0.3007157895735979 7 Q9HCL2 1 +Protein kinase c signaling 0.853134210815585 1.7882893898592698 0.073729330773357 1.0 0.3007157895735979 4 P41440,Q9NRA0 2 +Phagocytosis 0.4434122161358254 1.7877120382570482 0.0738224785142742 1.0 0.3007157895735979 48 P35579,Q06481,Q8WTV0,P84095,Q96JJ3,Q9NWH9,P51790,Q5KU26,Q9BZG1,P11274,Q14457,Q14185 12 +Negative regulation of protein catabolic process 0.4538620824086882 1.787584511651382 0.0738430661458409 1.0 0.3007157895735979 45 Q16850,P46379,Q13464,Q9H2J4,O75592,P10619 6 +Microtubule anchoring at microtubule organizing center 0.7366559481247811 1.78593701213973 0.0741094573325378 1.0 0.3014598987830888 7 Q8TD16,Q14203,Q9Y496,Q96RK4 4 +T cell apoptotic process 0.6337610525314569 1.7842845545912611 0.0743774387187894 1.0 0.302253716116279 13 Q9HCL2 1 +Positive regulation of peptidyl tyrosine phosphorylation 0.5458222613282686 1.7832276920548196 0.0745492464005415 1.0 0.3024418636446982 21 Q8WXW3,Q9H223,P78536,P14174 4 +Protein maturation 0.4091993867754235 1.7832065178335397 0.0745526918745567 1.0 0.3024418636446982 75 Q92896,Q9Y366,O75503,P35579,O75787,Q15392,Q9BXS4,P42892,Q9NRN7,Q92542,O75976,Q96F07,Q9H9S5,P78536,Q9H300,Q969M3,Q6N069,P17655,Q9NQH7,O75844 20 +G protein coupled receptor signaling pathway 0.4332332192886755 1.7825594285039188 0.0746580491491726 1.0 0.3024418636446982 53 P11717,Q99720,P07602,P22466,Q06481,Q13464,Q9NWH9,O75116,Q9Y4G8,Q99523,P42892,O43865,P00813,Q92888,Q9NRA0 15 +Sperm egg recognition 0.6429688672612186 1.782494682621881 0.0746685975829999 1.0 0.3024418636446982 12 P15291,P45880 2 +Binding of sperm to zona pellucida 0.6429688672612186 1.782494682621881 0.0746685975829999 1.0 0.3024418636446982 12 P15291,P45880 2 +Fucose metabolic process 0.8515468399850913 1.7821098473568169 0.0747313202776733 1.0 0.3025120212698285 4 Q9BTY2 1 +Response to camp 0.6863606686625787 1.781722560673601 0.0747944859619997 1.0 0.3025838858316967 9 P05067 1 +Positive regulation of t cell mediated cytotoxicity 0.8150383147770095 1.7801445163814338 0.0750523128306506 1.0 0.3030130263785597 5 Q9NUQ9,P30511,P04439 3 +Regulation of t cell mediated cytotoxicity 0.8150383147770095 1.7801445163814338 0.0750523128306506 1.0 0.3030130263785597 5 Q9NUQ9,P30511,P04439 3 +Positive regulation of cellular response to transforming growth factor beta stimulus 0.8141049977166832 1.7764024295466905 0.0756666109511825 1.0 0.3046324040892624 5 Q13573 1 +Ensheathment of neurons 0.523921976491167 1.7757206290876788 0.0757789754953179 1.0 0.304654105910498 27 Q9NR77,O15228,Q96PU8,P49770,Q9BX67,Q9Y4W6,P31751,Q8N3R9,Q7L576,Q92542,P31749 11 +Copii coated vesicle cargo loading 0.6591268511839066 1.7754090929498536 0.0758303637024031 1.0 0.304654105910498 10 Q15437 1 +Cellular component morphogenesis 0.3571992357461269 1.7752604383698485 0.0758548944477737 1.0 0.304654105910498 153 P84095,Q96N67,Q8N3R9,Q9UQB8,P05067,Q9NR77,Q06481,Q8N0X7,Q7Z406,Q15375,P42892,O75592,P33176,Q9NZM3,Q96TA1,Q13464,Q13641,Q9Y4G8,Q96F07,P09493,Q7L576,P41440,O75955,P07196,Q9GZY8 25 +Regulation of cell shape 0.4946076850304541 1.7709297933894093 0.0765723772252269 1.0 0.3065713403990465 32 P35579,P35580,P84095,O75844,Q7Z406,P09493,Q9UQB8 7 +Glucose import 0.600387693580878 1.7703133616536184 0.0766749534197472 1.0 0.3065713403990465 15 P11166,Q06481,Q99523,P31751,O75298,Q16625 6 +Copper ion homeostasis 0.8124800483767426 1.7698846413559357 0.0767463598657676 1.0 0.3065713403990465 5 P05067 1 +Cellular copper ion homeostasis 0.8124800483767426 1.7698846413559357 0.0767463598657676 1.0 0.3065713403990465 5 P05067 1 +T cell mediated cytotoxicity 0.7084901968569471 1.7662282077434532 0.0773575704776072 1.0 0.3074277851095398 8 Q9NUQ9,P30511,P04439,Q9BY67 4 +Protein localization to condensed chromosome 0.6395389530516711 1.7648368097056355 0.0775911962569684 1.0 0.3074277851095398 12 Q13123,P06493,Q96EA4,P50748,Q96DY7 5 +Regulation of myeloid leukocyte mediated immunity 0.6300544026530227 1.7647445128138246 0.0776067138757685 1.0 0.3074277851095398 13 P51809,Q7Z434,O95219,Q9NY93,Q9H2U1,P11274,Q9NRA0 7 +Positive regulation of interleukin 6 production 0.6826937108015508 1.7644586063253596 0.0776547985794851 1.0 0.3074354859982823 9 Q9NRA0,P05067 2 +Skin epidermis development 0.6393937589957003 1.7640887039237567 0.0777170459992986 1.0 0.3074992146634956 12 P22466 1 +B cell apoptotic process 0.707222063848467 1.7605017397600708 0.0783227727867474 1.0 0.308706046198664 8 P14174 1 +Aromatic amino acid transport 0.8676155329672454 1.7548959067633427 0.0792771144528159 1.0 0.3111637433960181 3 P30825 1 +Positive regulation of cell killing 0.7058622066918314 1.7543579368610944 0.079369194057375 1.0 0.3111637433960181 8 Q9NUQ9,P30511,P04439,Q9BY67 4 +Lipoprotein localization 0.771154122899379 1.754276917199102 0.0793830690162602 1.0 0.3111637433960181 6 Q13432,O15260,A6NIH7 3 +Leukocyte migration 0.4285447478947138 1.7532555741151592 0.0795581475267097 1.0 0.3111637433960181 55 Q92538,P35579,P55011,Q99538,P84095,Q13464,P14174,P15291,P00813,Q9BX67,P11274,P05067,P78536 13 +Positive regulation of mast cell activation 0.8667582417582422 1.751579108135222 0.0798462075563095 1.0 0.3111637433960181 3 O95219,Q9NRA0 2 +Positive regulation of mast cell activation involved in immune response 0.8667582417582422 1.751579108135222 0.0798462075563095 1.0 0.3111637433960181 3 O95219,Q9NRA0 2 +Cdp choline pathway 0.8667414003797448 1.7515139426213364 0.0798574217630483 1.0 0.3111637433960181 3 P35790 1 +Regulation of protein kinase c signaling 0.7736885471024396 1.7502826262389797 0.0800695573183793 1.0 0.3117139030847261 2 Q9NRA0 1 +Regulation of hormone metabolic process 0.7698372655385193 1.7488012511388904 0.0803253804708898 1.0 0.3124390017965787 6 P22466 1 +Cellular response to exogenous dsrna 0.7274253129952077 1.7457401308152074 0.0808561183494076 1.0 0.3137164978139803 7 Q5KU26,P41440,O75955 3 +Eye photoreceptor cell development 0.7690426204379994 1.7454958422757711 0.0808985955570067 1.0 0.3137164978139803 6 P54802,Q15555,O15078 3 +Leukocyte mediated immunity 0.4257933553109471 1.745009624385382 0.0809831936710281 1.0 0.3137164978139803 57 Q96FV9,P30511,Q9NY93,Q9UQ84,Q9BY67,P02786,Q7Z434,P33176,P04439,P78536,O15400,O96028,P11274,Q9NRA0,Q9NUQ9,P51809,Q9NQT5,O95219,Q9H2U1 19 +Ion transport 0.3879423731788185 1.7450084545229774 0.0809833973045244 1.0 0.3137164978139803 240 Q86VD7,O96008,Q9HC07,O43772,P14174,Q01650,Q7L0J3,P14373,Q9H813,O75027,Q9HC21,Q7KZN9,P05067,P46939,Q9UHG3,P11166,P21796,Q8N4V1,O95563,Q70HW3,P22466,Q9UBX3,Q9NWR8,P02786,Q9BQT8,P53985,Q8TB61,Q96GC9,P16615,Q07960,O75251,Q6P4Q7,Q9HD20,P80404,P30825,O43865,Q9BPX6,P00403,P33176,P20674,O14936,P55011,P07602,O15173,P00846,P45880,O43707,P61201,P51790,O75964,P51798,P41440,Q9NRA0,Q9Y6M7,Q13423,P51809,Q13555,Q9H4I9,P25705,O95219,O43681,O75844,Q8IYU8 63 +Amino acid transport 0.5319900641825946 1.7442296670615718 0.0811190501531684 1.0 0.3137895014684942 24 P55011,Q96H78,P80404,Q01650,Q7L0J3,Q6P4A7,Q15758,P30825,P08195,Q9Y619 10 +Posttranslational protein targeting to endoplasmic reticulum membrane 0.6527711381727093 1.744089265353605 0.0811435255936088 1.0 0.3137895014684942 10 P46379 1 +Primitive hemopoiesis 0.7714913485306218 1.7405993606724917 0.0817538297993123 1.0 0.3142139137746232 2 Q13769 1 +Regulation of cell cell adhesion 0.4302342023008193 1.7396778223703244 0.0819156056762309 1.0 0.3142139137746232 51 P23396,Q9NUQ9,Q9HCL2,P02786,P80404,Q15375,Q9BZE4,P30825,P04439,P00813,O75955,P41440,Q9Y6D9 13 +Regulation of protein binding 0.4252238436485088 1.7393122925799267 0.0819798462443237 1.0 0.3142139137746232 57 Q14012,P19474,Q9NVN8,Q08379,P16615,Q13464,Q9Y4G8,Q92797,O75955,P10586,P41440,P05067,Q96D46 13 +Embryonic digestive tract development 0.8634642618929743 1.7388280828896778 0.0820650072939597 1.0 0.3142139137746232 3 O94788 1 +Xenobiotic transport 0.7258130537077223 1.7387051272956398 0.0820866436978478 1.0 0.3142139137746232 7 P41440,Q01650 2 +Regulation of smad protein signal transduction 0.8627080945822956 1.735899431613857 0.0825816183266585 1.0 0.3142139137746232 3 Q8N1F7 1 +Retinal rod cell development 0.8623626373626379 1.7345612813687306 0.0828185424955765 1.0 0.3142139137746232 3 Q15555,P54802 2 +Retinal rod cell differentiation 0.8623626373626379 1.7345612813687306 0.0828185424955765 1.0 0.3142139137746232 3 Q15555,P54802 2 +Camera type eye photoreceptor cell differentiation 0.8623626373626379 1.7345612813687306 0.0828185424955765 1.0 0.3142139137746232 3 Q15555,P54802 2 +Cellular response to biotic stimulus 0.4702395591095568 1.7339305740783215 0.0829304022713155 1.0 0.3142139137746232 37 Q9NUQ9,Q8WTV0,P08670,P14174,O75844 5 +Lymphocyte activation involved in immune response 0.5073242737828144 1.7330338211085066 0.0830896576195867 1.0 0.3142139137746232 29 P00813,Q9UQ84,O96028 3 +Non motile cilium assembly 0.5440249129686188 1.732320667178716 0.0832164842147467 1.0 0.3142139137746232 18 Q15555,O15078,Q8WXW3,Q14203,Q9Y366,Q9UPN4 6 +Response to light stimulus 0.4127473644565428 1.7307080558747812 0.0835038477086766 1.0 0.3142139137746232 66 P22830,Q13432,Q9BRK5,Q96K76,O95155,Q15555,P27544,Q9P2X3,Q9UNS2,P31751,Q13330,Q9H2U1,Q13049,P05067 14 +Positive regulation of release of cytochrome c from mitochondria 0.7653139291336912 1.7299742974767345 0.0836348674769538 1.0 0.3142139137746232 6 Q9GZY8 1 +Modified amino acid transport 0.7004669182750702 1.729950463726696 0.0836391260169313 1.0 0.3142139137746232 8 O43772 1 +Cell junction organization 0.3621358067673388 1.728766278178257 0.0838509337815101 1.0 0.3144056115848068 136 Q14012,Q9BQT9,Q16352,Q13136,Q12834,O00192,Q9UQB8,P05067,Q16625,P35221,Q8IUD2,Q14203,Q96GC9,O75116,Q15375,Q9Y6W5,P12814,Q13464,Q9Y4W6,Q9Y4G8,Q13641,Q7L576,P41440,P11274,Q9BX67,Q9BRK5,Q15555,P49354,O75955,P10586,Q99538,Q9H2U1,P07196 33 +Organic cation transport 0.7230116349752764 1.726471527180149 0.0842626174112615 1.0 0.3155940527325662 7 Q86VD7,O43772 2 +Positive regulation of leukocyte degranulation 0.7227946589369185 1.725523494021782 0.084433173549147 1.0 0.3157965461837758 7 Q9NRA0,P30511,O95219 3 +Lactation 0.6316010410433868 1.7238644109940673 0.0847323233920502 1.0 0.31623183055698 12 O75592,Q9UNS2,Q13505,P61201 4 +Negative regulation of viral process 0.5366631587904795 1.7236827640484174 0.0847651282267396 1.0 0.31623183055698 21 O60858,P14373,Q13049,P19474 4 +Tissue migration 0.4190164491577883 1.722403138533625 0.0849965155483265 1.0 0.3167827184587184 61 P35579,Q15555,P42785,Q8WTV0,Q13464,O75116,P25705,P57105,P78536,Q14185 10 +Positive chemotaxis 0.6986898856007038 1.72190048040794 0.0850875479503225 1.0 0.3169023655634429 8 P14174 1 +B cell homeostasis 0.8357843239782536 1.7205944610845514 0.0853244392689229 1.0 0.3174297816018055 4 P14174 1 +Regulation of leukocyte migration 0.474848624726297 1.7186795282679848 0.0856727416689111 1.0 0.3180153079331225 34 Q99538,P84095,P14174,P00813,Q9BX67,P11274,P05067,P78536 8 +Cell cell recognition 0.6064662885725097 1.71808748749609 0.0857806587581162 1.0 0.3182386020631005 14 P15291,P78371,P45880 3 +Regulation of glucose transmembrane transport 0.6061751120975576 1.7164941979560029 0.0860716289956431 1.0 0.3189628832024305 14 P31751,O75298,Q16625,Q06481 4 +Primary alcohol metabolic process 0.5353879218503317 1.7153681137158068 0.0862777576488291 1.0 0.3194487531649067 21 P30837 1 +Cellular transition metal ion homeostasis 0.5329540250569049 1.7149415470573768 0.0863559443258488 1.0 0.3194487531649067 22 P05067,O75027 2 +Response to lipid 0.3551852735999048 1.714535408875329 0.0864304397787283 1.0 0.3194487531649067 157 O15118,Q8WTV0,O94788,P14174,Q9P1Z2,Q13126,P16278,P11717,P02786,O95831,O75116,O75592,O15173,Q01664,Q13573,P78536,P11274,Q9NRA0,P08670,P25705,Q9NS86,Q96HY6,P07196 23 +Retrograde transport endosome to golgi 0.460288733592009 1.71344030470339 0.0866315667345127 1.0 0.3197928693363205 40 Q92538,Q8NBN3,O60499,Q4J6C6,Q8IWJ2,O15260,Q8IUD2,Q14203,P14373,Q93009,O43752,O75503,Q9Y5X2 13 +Tetrapyrrole biosynthetic process 0.5900899581729524 1.712155064860568 0.0868680958839969 1.0 0.3202142087807624 15 P22830,Q7KZN9,O75027 3 +Protein insertion into er membrane 0.6052843236366378 1.7116185422711758 0.0869669889497741 1.0 0.3202142087807624 14 P46379,O43681 2 +Detection of muscle stretch 0.7648997528151588 1.7115154585270274 0.0869859999839681 1.0 0.3202142087807624 2 P35222 1 +Synaptic vesicle clustering 0.7648997528151588 1.7115154585270274 0.0869859999839681 1.0 0.3202142087807624 2 P35222 1 +Interferon beta production 0.6290063746262218 1.710440082254988 0.0871845244157669 1.0 0.3205907760387722 12 Q7Z434,P41440,O75955 3 +Secretory granule localization 0.763526503707769 1.7054500367958956 0.0881105230612893 1.0 0.3227489912904731 2 P33176 1 +Positive regulation of hemopoiesis 0.5887090264705457 1.70433369214307 0.0883187639514895 1.0 0.3231564657928471 15 P00813 1 +Response to hydrogen peroxide 0.4919114529569307 1.7036686246517845 0.0884430129040307 1.0 0.3234334769371883 31 P23396,Q99720,Q9P2X3,Q9NWH9,O95831,Q14457 6 +Response to nerve growth factor 0.6184140221325094 1.7031609123198947 0.0885379593249722 1.0 0.3236030844664234 13 Q9Y4G8,P05067 2 +Response to phorbol 13 acetate 12 myristate 0.7627025542433346 1.701809769207153 0.0887910345780074 1.0 0.3239948868528277 2 Q9NRA0 1 +Cell part morphogenesis 0.3617063217590419 1.7014089174695108 0.0888662279515095 1.0 0.3240917771433542 135 P84095,Q96N67,Q9UQB8,P05067,Q06481,Q8N0X7,Q7Z406,Q15375,P42892,O75592,P33176,Q9NZM3,Q96TA1,Q13464,Q13641,Q9Y4G8,Q96F07,Q7L576,P41440,O75955,P07196,Q9GZY8 22 +Regulation of myosin light chain phosphatase activity 0.8307377366063204 1.7008428414479746 0.0889725021387604 1.0 0.3243018499729543 4 O75116 1 +Intrinsic apoptotic signaling pathway 0.400785015220537 1.7000289715686552 0.0891254761526787 1.0 0.3246818193577356 87 P46379,Q07820,P14174,O60313,P09601,O95831,Q15118,Q13049,Q14457,P23396,Q96RU2,Q15233,Q8N2F6,Q8WUK0,Q7LG56,P45880,Q13573,Q8IXB1,Q9H300,P31749,Q96K76,O75569,P23246 23 +Regulation of neuron projection regeneration 0.8294267166771161 1.6957073758663082 0.0899413109933857 1.0 0.326793998902036 4 P10586 1 +Regulation of glucose import 0.6258665715124785 1.6941748400238028 0.090232064312411 1.0 0.327459828166446 12 P31751,O75298,Q16625,Q06481 4 +Cellular hormone metabolic process 0.5319249096616989 1.6927598932991106 0.0905011796632377 1.0 0.3275537998156794 21 O94788,Q9HB40 2 +Glycerophospholipid catabolic process 0.6417841869650582 1.6897450956785094 0.0910767318095775 1.0 0.3290912494833053 10 Q8WTV0 1 +Regulation of membrane protein ectodomain proteolysis 0.8272718600966564 1.6872626640051185 0.0915528567590899 1.0 0.3299170819825941 4 Q9Y5X1 1 +Negative regulation of leukocyte migration 0.6662550369059503 1.6867482021872773 0.0916517792222055 1.0 0.3300950297067869 9 P09601,P14174,P00813,P11274,P31749 5 +Middle ear morphogenesis 0.8268124124504055 1.6854615173485827 0.0918995634386541 1.0 0.3305561389369953 4 P54802 1 +Positive regulation of autophagy 0.4569652454202209 1.6851615193698175 0.0919574130615221 1.0 0.3305561389369953 40 P21796,P19474,Q13464,O60858,Q9BXS4,O95219,Q13049,Q14457 8 +Positive regulation of long term synaptic potentiation 0.825450916345122 1.6801228766796663 0.0929334107504793 1.0 0.3330905410599483 4 P05067 1 +Positive regulation of cell adhesion 0.4064242014159836 1.6797088521387575 0.0930139766320443 1.0 0.3332000679028556 67 Q9NUQ9,Q9HCL2,P02786,Q13464,P30825,P09493,P00813,O75955,P41440,Q14185,P46939 11 +Negative regulation of cell projection organization 0.4944245926579771 1.679147153704202 0.0931233682835412 1.0 0.3334126828980309 30 Q9NR77,Q8N0X7,P08670,Q9Y4G8,O14976,Q9NQX7,Q96G23 7 +Transepithelial transport 0.7525943681859455 1.6768851500727875 0.0935649425383813 1.0 0.3341938616009479 6 P55011,O43865 2 +Negative regulation of biomineralization 0.8474647673040423 1.676745098554702 0.0935923376478116 1.0 0.3341938616009479 3 O75116 1 +Response to growth factor 0.3819271403697752 1.6754720244895809 0.0938416554989358 1.0 0.3342427758255099 116 Q8WUH2,P49354,Q06481,Q92896,Q96TA1,Q13464,Q99523,Q9Y4G8,O75116,Q96F07,Q9Y448,Q8N3R9,Q13573,Q14457,P78536,Q9UQB8,P05067 17 +Neurotransmitter secretion 0.5244473607002389 1.6752257099533967 0.0938899549917597 1.0 0.3342427758255099 23 Q7L0J3,P50897,Q4J6C6 3 +Positive regulation of myoblast fusion 0.788759316066401 1.6743719991266193 0.0940575123327076 1.0 0.3342427758255099 5 P41440,O75955 2 +Regulation of myoblast fusion 0.788759316066401 1.6743719991266193 0.0940575123327076 1.0 0.3342427758255099 5 P41440,O75955 2 +Membrane lipid biosynthetic process 0.5043231229003969 1.6729266318634872 0.0943417402716317 1.0 0.3348955862705821 28 O15269,P27544,Q8NBX0,Q16739,P04062,O60512,O95470,Q9NRA0,Q99805,Q969N2,Q5H8A4,Q96G23,Q6Y1H2 13 +Phosphatidylcholine biosynthetic process 0.6877729163368821 1.6723304447229714 0.0944591794034586 1.0 0.3351339256470951 8 P35790,Q9Y6K0 2 +Retinoic acid receptor signaling pathway 0.6862912353196771 1.6655876283336946 0.095795576951031 1.0 0.3370173094019449 8 O94788,Q13573 2 +Carbohydrate transport 0.527227182200839 1.662023987050839 0.0965079650413134 1.0 0.338973416484065 21 P11166,Q06481,Q99523,P31751,O75298,Q16625 6 +Protein deglycosylation 0.6604378119910082 1.659128581608161 0.0970898849897989 1.0 0.3401369647429425 9 O60858,O60476,O60502 3 +Body fluid secretion 0.5652065657516897 1.6590903228851714 0.0970975929851427 1.0 0.3401369647429425 16 P00813,Q9UNS2,Q13505 3 +Glutamate receptor signaling pathway 0.8199020948977096 1.6583461260615149 0.0972476238684234 1.0 0.3401369647429425 4 P05067 1 +Lipid phosphorylation 0.7525405108486625 1.656852775429982 0.0975492440233196 1.0 0.3408340917290922 2 Q9NRA0 1 +Regulation of protein glycosylation 0.8421421299744414 1.6560397236919393 0.0977137745873455 1.0 0.3408727120814048 3 Q9BXS4 1 +Positive regulation of phosphorus metabolic process 0.3461838570387128 1.6544932555895948 0.0980273325434915 1.0 0.3414302753462017 146 Q05639,Q14012,Q86XL3,P54619,P51114,Q86VI3,Q96N67,P14174,Q92797,P05067,Q13432,P02786,Q7Z434,O75116,Q15375,Q8NDZ4,P00403,P23396,Q8WXW3,Q13464,Q9Y4G8,P12956,P78536,P41440,Q9H223,P31749,P49792,P17655,Q9Y5X1,Q9NWH9,P31751,O75955,Q96HY6 33 +Response to increased oxygen levels 0.6343998867382464 1.653081394824678 0.0983142992884227 1.0 0.3418147341276354 10 Q9Y487 1 +Regulation of fatty acid transport 0.7467912472738868 1.6525941411651932 0.0984134912689613 1.0 0.3418147341276354 6 P31751,P14174 2 +Adult behavior 0.523460886167362 1.6521851307472717 0.0984968166779318 1.0 0.3418147341276354 22 O15118,P50897,P80404,P51790,O75844,Q92542,P05067 7 +Cellular metabolic compound salvage 0.6085741117797956 1.6508513559849054 0.0987689306217667 1.0 0.3425806271383819 13 P00813,Q13126 2 +Protein quality control for misfolded or incompletely synthesized proteins 0.6082587070766526 1.6491709651434094 0.0991126144477141 1.0 0.3431447357329977 13 P46379 1 +Negative regulation of mrna catabolic process 0.5204135412330196 1.648213238939341 0.0993089210681774 1.0 0.3431447357329977 23 Q06787,A2RRP1,Q9NZI8,O60506,Q16539,P98175,P35637,Q9Y2W1,Q14103,Q92804,Q99729,Q13151 12 +Regulation of collateral sprouting 0.8394862955459 1.645699226635703 0.0998256983360315 1.0 0.3431447357329977 3 Q8N0X7 1 +Organelle fusion 0.4182279098710203 1.6432004061426149 0.1003414758965073 1.0 0.3439173116761462 54 Q8WUH2,P06493,Q9Y6C9,O60313,P02786,Q86Y82,O60343,O95140,Q9BZG1,Q8N2A8,O60499,Q9Y4W6,Q9Y3D6,O43752,O15400,Q9H300,Q969M3,Q9NX63,Q15075,P51809,P31751,Q9GZY8 22 +Neuromuscular process controlling balance 0.6061029020036919 1.6376794307653677 0.1014885836476944 1.0 0.3467786835100451 13 P07196,P11274,P10253,P05067 4 +Cholesterol efflux 0.6556268134178325 1.6362411220927608 0.1017891331544023 1.0 0.3474492798195607 9 Q8WTV0,O15118 2 +Respiratory system development 0.4938697111424484 1.6347968158856945 0.1020916484970559 1.0 0.3475915451895166 29 O94788,P46379 2 +Positive regulation of skeletal muscle tissue development 0.8131724043599667 1.6318953702930636 0.1027015295082089 1.0 0.3487769067855231 4 P41440,O75955 2 +Positive regulation of muscle tissue development 0.8131724043599667 1.6318953702930636 0.1027015295082089 1.0 0.3487769067855231 4 P41440,O75955 2 +Response to acid chemical 0.5243628667106094 1.6298639080552042 0.1031302631570629 1.0 0.350054479579985 20 Q9UQB8 1 +Diencephalon development 0.6782339285572198 1.6288598592351016 0.1033426893429729 1.0 0.3505274350815083 8 O94788 1 +Regulation of neuron differentiation 0.512072562701084 1.628459804091113 0.1034274256896661 1.0 0.3505274350815083 25 Q8WUJ1,Q13049,P05067,Q13464 4 +Neurotrophin signaling pathway 0.6780261431703166 1.6279113769350968 0.1035436787040784 1.0 0.3505648024417045 8 Q99523,Q9Y4G8,Q96F07 3 +Semaphorin plexin signaling pathway 0.6999150511533831 1.625157338496398 0.1041290379741504 1.0 0.3517088600625128 7 P42892 1 +Regulation of synapse assembly 0.6532837627486279 1.625079984255076 0.1041455171699441 1.0 0.3517088600625128 9 Q13641,Q9BQT9,P05067 3 +Neuron projection arborization 0.6772637034435963 1.6244304897854225 0.104283964256675 1.0 0.3518447631129189 8 Q9HCE1,Q13641,Q9NZI8,Q13464 4 +Macropinocytosis 0.8339560127086707 1.6241482280678166 0.1043441770840654 1.0 0.3518447631129189 3 Q06481 1 +Glycolipid transport 0.7756304615579914 1.6212315036427682 0.104967998739696 1.0 0.3531623145092051 5 P07602 1 +Cellular ion homeostasis 0.3892702185518193 1.6204962897297928 0.1051257106936791 1.0 0.3531748464739703 100 Q9HC07,Q7L0J3,O75027,O75503,P05067,Q9NWR8,Q9Y487,P02786,P16615,O75787,Q9HD20,Q9BPX6,P55011,P50897,Q93050,Q9Y6M7,Q9H4I9,Q9NWW5,O60826,Q8IYU8 20 +Antibacterial humoral response 0.7443010162043369 1.6203241036529057 0.1051626737812332 1.0 0.3531748464739703 2 P04439 1 +Cation transmembrane transport 0.3475189490840042 1.6181164810678428 0.105637497331176 1.0 0.3544940879851569 141 O43772,Q01650,O75027,Q7KZN9,P05067,P46939,P21796,Q8N4V1,Q70HW3,P22466,Q9NWR8,P16615,O75251,Q6P4Q7,Q9HD20,P30825,Q9BPX6,P00846,O43707,O75964,Q9NRA0,Q9Y6M7,Q9H4I9,P25705,Q8IYU8 25 +Pre mirna processing 0.7745641967995215 1.6169076728460674 0.1058982119249998 1.0 0.3550857422466408 5 O75569,Q5TAX3,Q6ZN17 3 +Respiratory chain complex iii assembly 0.6976999920612321 1.615400461157848 0.1062240004499837 1.0 0.3550857422466408 7 Q9BSK2,Q69YU5,Q9BRT2,Q6DKK2 4 +Signaling receptor ligand precursor processing 0.8087098873127425 1.6143326627913153 0.1064552889672239 1.0 0.3550857422466408 4 O75787,P42892 2 +Histamine secretion 0.8314041225628883 1.61419543562748 0.1064850417337803 1.0 0.3550857422466408 3 O95219 1 +Histamine production involved in inflammatory response 0.8314041225628883 1.61419543562748 0.1064850417337803 1.0 0.3550857422466408 3 O95219 1 +Histamine transport 0.8314041225628883 1.61419543562748 0.1064850417337803 1.0 0.3550857422466408 3 O95219 1 +Regulation of histamine secretion by mast cell 0.8314041225628883 1.61419543562748 0.1064850417337803 1.0 0.3550857422466408 3 O95219 1 +Negative regulation of myosin light chain phosphatase activity 0.8313156955382845 1.6138504638807276 0.1065598655426218 1.0 0.3550857422466408 3 O75116 1 +Negative regulation of bicellular tight junction assembly 0.8313156955382845 1.6138504638807276 0.1065598655426218 1.0 0.3550857422466408 3 O75116 1 +Response to lead ion 0.7737053787088337 1.6134242195280508 0.1066523747985761 1.0 0.3551348192318405 5 P05067 1 +Positive regulation of toll like receptor signaling pathway 0.7367767631103266 1.6105775089456809 0.1072718391894715 1.0 0.3563652920797551 6 P41440 1 +Regulation of endothelial cell differentiation 0.673559318264612 1.6075058136461422 0.1079434551172997 1.0 0.3571875229955178 8 O75116,Q13464,P35222 3 +Positive regulation of i kappab kinase nf kappab signaling 0.4396634087591837 1.6062630917458047 0.1082161161160795 1.0 0.3576607051991258 43 Q13325,P19474,Q8WVQ1,O60826,P09601,P02786,Q7Z434,Q5T9L3,Q8TB61,O60858,P14373,Q9H2U1,Q9NY93,O43657,P32929,Q13049,P35222 17 +Antigen processing and presentation of peptide antigen 0.5559988228269008 1.6047302791474285 0.1085531753302704 1.0 0.3578870891764432 16 P10321,Q9UIQ6,Q9NZ08,P30511,Q99538 5 +Regulation of immune system process 0.3713030851158973 1.6034276870061022 0.1088402624089059 1.0 0.3586561169290507 215 Q07666,P23246,P46379,P26038,Q9HCL2,P84095,P30511,P14174,Q01650,Q5KU26,P14373,Q8TCT8,Q9NY93,Q9Y6D9,P05067,P19474,P22466,Q06481,Q9BY67,P28070,P02786,Q7Z434,Q9NPR9,P30825,P00813,O43657,P23396,Q15046,Q15233,Q8WXW3,P12956,P04439,O96028,O15400,P41440,P78536,P11274,Q9NRA0,P31749,Q9NPF0,Q9BX67,Q9NUQ9,P51809,Q9NZ08,Q9NQT5,O95219,O75955,Q99538,Q9H2U1,P26583,P49770 51 +Fat pad development 0.7393573194177399 1.5983765163058032 0.1099592077451239 1.0 0.3613945354889608 2 Q96RK4 1 +Regulation of hormone levels 0.3925664584261285 1.593588219657563 0.1110282947399063 1.0 0.3624603272180285 77 O95563,Q9HB40,P22466,Q96TA1,O94788,Q13555,P53985,O75787,Q01650,O95219,P42892,Q9UBM7,O75844 13 +Actin cytoskeleton reorganization 0.4932457056785657 1.5931060966215265 0.1111363918966328 1.0 0.3626355431965056 28 Q9Y5S2,Q9UQB8 2 +Digestive system development 0.5830211752971735 1.5891281598510405 0.1120314613921003 1.0 0.3648414600467078 14 O94788 1 +Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway 0.801596951340724 1.586302900798722 0.1126706146014386 1.0 0.3665646020944267 4 P30511,P10321 2 +Positive regulation of peptidyl serine phosphorylation 0.5155716859880674 1.5854457298125035 0.1128650981230416 1.0 0.3670181302068456 21 Q14012,P05067,Q96N67,P14174 4 +Axoneme assembly 0.8009473642887828 1.5837409605110622 0.1132526795144355 1.0 0.3675609369725688 4 Q9UPN4,Q15555 2 +Ion transmembrane transport 0.35807033565232 1.582395205689561 0.1135593785183421 1.0 0.36837689341174 183 Q86VD7,O43772,Q01650,O75027,Q7KZN9,P05067,P46939,P21796,Q8N4V1,O95563,Q70HW3,P22466,Q9UBX3,Q9NWR8,P53985,P16615,O75251,Q6P4Q7,Q9HD20,P30825,O43865,Q9BPX6,P00846,P45880,O43707,O75964,P41440,Q9NRA0,Q9Y6M7,Q9H4I9,P25705,O75844,Q8IYU8 33 +Negative regulation of adaptive immune response 0.8230769230769235 1.581683330187992 0.1137218800772843 1.0 0.3687245191994869 3 P14373,P30511 2 +Bone development 0.4865093665191778 1.580754067728413 0.1139342805747887 1.0 0.3692335172518566 29 Q92896,O96028,Q7RTS9,Q9NX62 4 +Negative regulation of reproductive process 0.7293778722809946 1.579459516109398 0.1142306953345568 1.0 0.3699751552369955 6 P00813 1 +Small rna loading onto risc 0.7291903618720276 1.5786700954874264 0.1144117474901431 1.0 0.3699751552369955 6 O75569,Q5KU26 2 +Nucleoside salvage 0.7651157852646857 1.578543679804759 0.1144407616604303 1.0 0.3699751552369955 5 Q13126 1 +Purine ribonucleoside salvage 0.7651157852646857 1.578543679804759 0.1144407616604303 1.0 0.3699751552369955 5 Q13126 1 +Amyloid precursor protein catabolic process 0.519478476795489 1.576303250436236 0.1149559329123157 1.0 0.3711004752881588 18 Q13464,Q15392,O75116,P78536,Q92542 5 +Positive regulation of cyclin dependent protein kinase activity 0.798817117028882 1.5753369434326814 0.1151786908741097 1.0 0.3714596405102579 4 P78536 1 +Negative regulation of proteolysis 0.3905672810861251 1.575041820517214 0.1152467917306219 1.0 0.3714994549110468 73 P46379,P19474,Q06481,Q15392,Q9BXS4,P05067 6 +Positive regulation of organic acid transport 0.6884000313732354 1.574364224276515 0.1154032697371358 1.0 0.3715817370120727 7 P80404,P14174 2 +Cytochrome complex assembly 0.5508717647054272 1.5743632927494808 0.1154034849705825 1.0 0.3715817370120727 16 Q9BSK2,Q69YU5,Q15070,Q7KZN9,Q9Y2R0,Q6DKK2 6 +Skin morphogenesis 0.7338643229881873 1.573965658010971 0.1154953890667871 1.0 0.3715817370120727 2 P04062 1 +Positive regulation of transmission of nerve impulse 0.7338643229881873 1.573965658010971 0.1154953890667871 1.0 0.3715817370120727 2 P04062 1 +Negative regulation of interleukin 2 production 0.7335896731667089 1.5727444685298582 0.1157779986297045 1.0 0.3723111992614484 2 P14373 1 +Regulation of epidermal growth factor activated receptor activity 0.7635773139415801 1.5722887708506077 0.1158835960567674 1.0 0.3724550319709943 5 P05067 1 +Rna stabilization 0.4995831622996535 1.5718556161097623 0.1159840398401252 1.0 0.3724550319709943 26 Q9NZI8,O60506,P98175,Q9H814,P35637,Q92804,Q9H2U1,Q9Y2W1,Q13151 9 +Glycosphingolipid metabolic process 0.5926413774950449 1.5656938240625244 0.1174203128193638 1.0 0.3746990154767343 13 P16278,Q16739,O60512,Q9NWW5,P06280 5 +Negative regulation of synapse organization 0.7313924745948883 1.5629728269410068 0.1180589863378061 1.0 0.3761965690907709 2 Q15375 1 +Reactive oxygen species biosynthetic process 0.6078833321226922 1.5584988578458308 0.1191150385373447 1.0 0.3781150556333149 11 Q92538,Q9BSK2,P51790,O75027,Q9NRA0 5 +Autophagosome membrane docking 0.8168092580543859 1.5571793999680643 0.1194278978495255 1.0 0.3786456812291293 3 P16615 1 +Positive regulation of kinase activity 0.3888067136302218 1.5569131498268582 0.1194911069539326 1.0 0.3786456812291293 72 Q05639,Q14012,Q13432,P54619,P23396,Q8WXW3,P31749,Q9Y5X1,Q9NWH9,P14174,Q15375,Q9Y4G8,P12956,P78536,Q8NDZ4,P49792 16 +Negative regulation of intrinsic apoptotic signaling pathway 0.4465785917957099 1.556120885970436 0.1196793493662478 1.0 0.3788235177326884 38 O60313,Q96K76,Q15233,Q8N2F6,Q07820,Q7LG56,P45880,P14174,Q9H300,Q13049 10 +Phosphatidylcholine catabolic process 0.7938349522695733 1.5556677273162882 0.1197871245479813 1.0 0.3789846205428299 4 Q8WTV0 1 +Vitamin metabolic process 0.4544459199785141 1.5545438433271257 0.1200547470820854 1.0 0.379470958163157 34 P11166,Q9NVS9,Q9NPF0,Q9H2D1,Q99538,O94788,Q8N0U8,Q9NUN5,O14678,Q8NFF5,P04062,Q9NRN7,Q9Y5Z9,O00764,Q9HC21,P41440,Q99707 17 +Macrophage activation 0.6143924395259764 1.5532174446824634 0.1203711950993695 1.0 0.379767579715652 10 P14174 1 +Regulation of biological process involved in symbiotic interaction 0.6143422640735057 1.5529660928679945 0.1204312353534711 1.0 0.379767579715652 10 Q9BTY2,P19474 2 +Regulation of reproductive process 0.531665066312524 1.551979396621023 0.1206671535526309 1.0 0.379767579715652 17 P00813,P15291,Q12834 3 +Protein localization to synapse 0.6139848261542689 1.551175397614164 0.1208596563161497 1.0 0.3798527783181629 10 Q9BQT9,Q9UQB8,Q14168 3 +Sulfur amino acid biosynthetic process 0.7224587985837406 1.5503050973688144 0.121068304456829 1.0 0.3799708490795345 6 Q13126 1 +Ion homeostasis 0.3696231188629391 1.547527542638356 0.1217360882379461 1.0 0.3817070851432635 119 Q9HC07,P30519,Q7L0J3,O75027,O75503,P05067,Q9NWR8,Q9Y487,P02786,P16615,O75787,Q6P4Q7,Q9HD20,Q9BPX6,P55011,P50897,Q93050,Q9Y6M7,Q9H4I9,Q9NWW5,O60826,Q8IYU8 22 +Regulation of neuronal action potential 0.7278220269156795 1.5470861190181409 0.1218424806701785 1.0 0.3817689497240888 2 P04062 1 +Negative regulation of amyloid beta clearance 0.8140173756550744 1.5462558219182023 0.1220427967925144 1.0 0.3817689497240888 3 Q16850 1 +Meiotic cell cycle 0.4051318497367941 1.5461917229169 0.1220582719106715 1.0 0.3817689497240888 58 P35579,Q9UQ84,Q9UQE7,P46379,Q8N2A8,Q9UH99,Q96CW5,Q9BTX1,Q08379,Q9BSJ2,Q12834,Q9Y2W6 12 +Macromolecule depalmitoylation 0.7567215134449528 1.5443890825965323 0.122494103251094 1.0 0.3817689497240888 5 P50897 1 +Negative regulation of production of molecular mediator of immune response 0.8134615384615391 1.5440804424898718 0.1225688461378036 1.0 0.3817689497240888 3 P30511,Q96FV9 2 +Bone morphogenesis 0.6595807826330473 1.5434621412712184 0.1227186863562663 1.0 0.3817689497240888 8 Q92896,Q9NX62 2 +Regulation of cellular extravasation 0.8131661477869805 1.5429242927215063 0.1228491458813363 1.0 0.3817689497240888 3 P11274 1 +Positive regulation of epithelial cell migration 0.449150205138958 1.5422498920014494 0.1230128802938332 1.0 0.3817689497240888 36 Q15555,Q8WTV0,O75116,P25705,P78536,Q14185 6 +Optic nerve development 0.726723427629769 1.5421960385014832 0.1230259624634677 1.0 0.3817689497240888 2 Q9H061 1 +Positive regulation of anion transport 0.6591916074187404 1.541675259888054 0.1231525268185964 1.0 0.3817689497240888 8 P80404,P14174 2 +Positive regulation of protein phosphorylation 0.3736334658806899 1.5415283860181133 0.1231882398179184 1.0 0.3817689497240888 114 Q14012,P54619,Q86VI3,Q96N67,P14174,P05067,P02786,Q7Z434,O75116,Q15375,Q8NDZ4,P23396,Q8WXW3,Q9Y4G8,P12956,P78536,P41440,Q9Y5X1,P31751,O75955,Q96HY6 21 +Glycerophospholipid biosynthetic process 0.4234638075904315 1.5406471944706863 0.1234026750889309 1.0 0.3822557062378183 46 Q96N66,O15228,Q9HCL2,Q9NX62,P17655,Q8WUK0,Q96PE3,Q9NPH0,P35790,Q9Y6K0,Q14457,Q969N2,Q5H8A4,Q9BXW7 14 +Regulation of integrin activation 0.7256248283438584 1.537305112786857 0.1242186100391873 1.0 0.384277152763064 2 Q9BX67 1 +Cell morphogenesis involved in neuron differentiation 0.3820828813911932 1.5372656334444563 0.1242282736082305 1.0 0.384277152763064 101 P41440,Q06481,O75592,P84095,Q96TA1,Q8N0X7,Q96N67,Q13641,Q9Y4G8,P42892,P07196,O75955,Q7L576,Q9UQB8,P05067,P33176 16 +Regulation of neural precursor cell proliferation 0.5955560902998905 1.5360725072180064 0.1245205982684412 1.0 0.3846569328504175 12 P48681,P35222,P35221,Q06481 4 +Myoblast fusion 0.6795572959545672 1.5352432702202463 0.1247240832311571 1.0 0.3850957213017609 7 P35579,P41440,O75955 3 +Isotype switching to iga isotypes 0.8110131801705955 1.534496000391576 0.1249076764634846 1.0 0.3853054853130547 3 O96028 1 +Glycosylceramide metabolic process 0.7171067283986364 1.527719394461319 0.1265822226670896 1.0 0.3895692146100777 6 O60512,P06280 2 +External encapsulating structure organization 0.483956986017747 1.5258318513932052 0.1270517461160665 1.0 0.3906533384270195 28 P07942,P15291,P39210,O75955,P41440,P05067 6 +Acid secretion 0.7860369127823497 1.5248440175364155 0.1272980079453505 1.0 0.391229993975955 4 Q7L0J3 1 +Positive regulation of protein kinase activity 0.4019938815078528 1.5239921531984395 0.1275106713645439 1.0 0.3916307871806669 59 P23396,Q14012,P54619,Q9Y5X1,P14174,Q9Y4G8,P12956,P78536,Q8NDZ4 9 +Positive regulation of dendrite development 0.7226036803076031 1.5238508586283726 0.1275459715116385 1.0 0.3916307871806669 2 Q7L576 1 +Positive regulation of ruffle assembly 0.8078028104215431 1.5219230356079496 0.1280283664734516 1.0 0.3924235607672234 3 Q8NCA5 1 +Cellular iron ion homeostasis 0.570885243247387 1.5218776310775326 0.1280397450259558 1.0 0.3924235607672234 14 O75027 1 +Positive regulation of dendritic spine development 0.6006606004286823 1.5214754235704473 0.1281405741327201 1.0 0.3925244517982132 11 Q14012,Q9UQB8 2 +Regulation of rna polymerase ii regulatory region sequence specific dna binding 0.8074175824175832 1.5204139357653337 0.1284069741870031 1.0 0.3930067381754715 3 O75844,Q96HY6 2 +Synapse maturation 0.7501290906535674 1.5175227098068316 0.1291347642401796 1.0 0.3945093691574127 5 P07196 1 +Modification of synaptic structure 0.6753653634306398 1.5166651736584154 0.1293512413918696 1.0 0.3946857521706808 7 Q9UQB8 1 +Microtubule anchoring at centrosome 0.7144837878734521 1.516640271977583 0.1293575318016158 1.0 0.3946857521706808 6 Q14203,Q9Y496,Q96RK4 3 +Intraciliary transport involved in cilium assembly 0.806211701366445 1.5156894423496132 0.1295978984971437 1.0 0.3946857521706808 3 Q9UPN4 1 +Receptor mediated endocytosis 0.3927808875208288 1.515652881850826 0.1296071477937039 1.0 0.3946857521706808 66 P11717,Q14108,P20645,Q9NZM3,P50897,P02786,Q9Y5X1,O14976,O00291,Q5VW38,O75955,P41440,Q9NUN5,P05067 14 +Mitochondrial genome maintenance 0.6297732508879582 1.5125962926719254 0.1303822364697411 1.0 0.3963259563631919 9 Q9BSK2,P39210 2 +Bone resorption 0.7135254299908573 1.5125905916751872 0.130383685479231 1.0 0.3963259563631919 6 Q9UBB6,P02786,O14773 3 +Positive regulation of smooth muscle contraction 0.7828249534038914 1.5121354252783454 0.130499414425091 1.0 0.3964425572235001 4 P00813 1 +Feeding behavior 0.6523540161996568 1.510248821904559 0.1309799452389213 1.0 0.3970515810404607 8 P05067 1 +Sphingolipid biosynthetic process 0.5056649457435195 1.507810527728033 0.1316030269389072 1.0 0.3985209010329307 20 O15269,P27544,Q16739,Q96G23,O60512,O95470,Q9NRA0,P04062,Q99805,Q6Y1H2 10 +Modification of postsynaptic structure 0.7123220091334105 1.507504139942672 0.1316814834840349 1.0 0.3985209010329307 6 Q9UQB8 1 +Dna damage response signal transduction resulting in transcription 0.7476515417348366 1.5074166612623436 0.1317038907510901 1.0 0.3985209010329307 5 Q9UNS2 1 +Positive regulation of response to biotic stimulus 0.4461606439985136 1.5018809025906374 0.1331278695259885 1.0 0.3993836085779656 35 Q9BY67,P30511,P14174,P12956,P23246 5 +Regulation of release of cytochrome c from mitochondria 0.567160497532545 1.501175505021807 0.1333101737352626 1.0 0.399750534472572 14 O60313,Q96A26,P02545,Q9H300,P31749,Q9GZY8 6 +Cellular response to testosterone stimulus 0.8013683013495628 1.496705484456766 0.1344699085735448 1.0 0.4011946880617174 3 O75116 1 +Defense response to gram positive bacterium 0.7449147883452291 1.4962477474637996 0.1345891061347961 1.0 0.4011946880617174 5 Q96EE3,P26583,P78536,P04439 4 +Cation transport 0.3518034041706877 1.495630802688163 0.1347498916100895 1.0 0.4011946880617174 181 Q86VD7,Q9HC07,O43772,Q01650,P14373,O75027,Q7KZN9,P05067,P46939,P21796,Q8N4V1,Q70HW3,P22466,Q9NWR8,P02786,P16615,Q07960,P80404,O75251,Q6P4Q7,Q9HD20,P30825,O43865,Q9BPX6,P33176,O14936,P55011,O15173,P00846,P61201,O43707,O75964,Q9NRA0,Q9Y6M7,Q13423,Q13555,Q9H4I9,P25705,O95219,O75844,Q8IYU8 41 +Membrane raft organization 0.6259537322367698 1.4942442309714563 0.1351117957049412 1.0 0.4013597390914059 9 P41440,O75955,P50897 3 +Gamma aminobutyric acid transport 0.8004201834036759 1.4929878287477985 0.1354403729133495 1.0 0.4019773740408231 3 Q7L0J3 1 +Mammary gland development 0.494831265497986 1.491760377674986 0.1357619745068103 1.0 0.4021301468005507 24 Q86VI3,Q9UNS2,P61201,P31751,Q13505,O75592,P00403 7 +Branched chain amino acid transport 0.8000000000000006 1.4913401050584527 0.1358722245805099 1.0 0.4021301468005507 3 Q96H78,Q01650 2 +Purine deoxyribonucleoside triphosphate metabolic process 0.7775171519188044 1.491119466721935 0.135930132281882 1.0 0.4021301468005507 4 P00813 1 +Entry into host 0.4466056920038641 1.490996827523144 0.135962327828867 1.0 0.4021301468005507 34 Q14108,P19474,O15118,Q8WTV0,P14373,Q9BTY2 6 +Positive regulation of mitophagy 0.743616296652349 1.4909465150877077 0.1359755376774623 1.0 0.4021301468005507 5 P21796,P27544 2 +Regulation of myeloid cell apoptotic process 0.6695459344693968 1.4908415101089896 0.1360031105920376 1.0 0.4021301468005507 7 P14174 1 +Negative regulation of lipid storage 0.7151881351277088 1.4908027346554398 0.1360132936031362 1.0 0.4021301468005507 2 Q9BZF1 1 +Chromosome organization involved in meiotic cell cycle 0.5215968776224355 1.489801514674433 0.1362764327593641 1.0 0.4021301468005507 17 O60566,P46379,Q9BTX1,Q92878,Q9NTJ3 5 +Positive regulation of signaling 0.3829179130044075 1.4868684248177408 0.1370495651455687 1.0 0.4036963981277297 285 O15344,Q9BQT9,Q86VI3,Q86SX3,P14174,P14373,O00291,Q9NY93,Q9UQB8,Q9UMX5,P05067,O95563,P19474,Q8WVQ1,P22466,Q06481,P02786,Q7Z434,P80404,O75787,O75116,P42892,Q9BZG1,P00813,P32929,Q13049,Q14457,Q92542,P33176,P29372,P23396,Q8WXW3,P55735,Q13464,O43707,O60858,Q9Y4G8,Q14168,Q13641,Q96F07,O14523,Q13573,Q8N1F7,P78536,Q7L576,P41440,Q9NRA0,Q15555,Q96K76,P51809,O75569,Q9NWH9,Q9NS86,O95219,O75955,Q99538,O60826,Q9NQX7,P23246 59 +Regulation of tissue remodeling 0.6685132170417821 1.4862550206978549 0.1372116791399302 1.0 0.4037125047189653 7 O75116,P11274,Q13464 3 +Regulation of endothelial cell development 0.6684253081930438 1.485864549533466 0.1373149521367285 1.0 0.4037641333128958 7 O75116 1 +Water soluble vitamin metabolic process 0.4869992614002546 1.483435525077687 0.1379587347254529 1.0 0.4047619412413971 26 P11166,Q9NVS9,Q9H2D1,Q9NUN5,O14678,Q8NFF5,Q9NRN7,Q9NPF0,O00764,Q9HC21,P41440,Q99707 12 +Regulation of autophagy 0.3743428297420886 1.483209417389579 0.1380187799040153 1.0 0.4047619412413971 107 P27544,O15118,P14373,P21796,P19474,Q08379,Q9Y487,Q9BXS4,Q8NHS3,Q13049,P10619,Q14457,P07602,Q13464,O60858,Q93050,Q9H300,Q9NZ45,Q9NWH9,O95219,O75844 21 +Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 0.5354990738983206 1.4829218559440975 0.1380951738438103 1.0 0.4048078061246406 16 P46379,O95831 2 +Organophosphate ester transport 0.4354632399407186 1.480953759928313 0.1386188957719822 1.0 0.4052732349840798 39 Q9BSK2,Q86VD7,Q14108,P61916,Q8WTV0,Q8TB61,Q9H1P3,O14523,Q9HC21,P41440 10 +Cobalamin metabolic process 0.7056480133411903 1.4792715752697527 0.1390677466233498 1.0 0.4060605623724108 6 O14678,Q9NUN5 2 +Response to reactive oxygen species 0.4278437448560511 1.4777757594077838 0.1394678086911318 1.0 0.4068625259671679 42 P23396,Q99720,Q9P2X3,P17655,Q9NWH9,O95831,Q9Y5Z4,P39210,P09493,Q14457 10 +Positive regulation of locomotion 0.38016439875691 1.4765654791451923 0.1397921509893245 1.0 0.4074519256526112 94 P07942,Q15555,Q9UH99,Q8WTV0,Q9NWH9,O43707,P25705,Q9Y4G8,O75116,Q13641,P31751,O95684,Q96HY6,P78536,Q13049,P05067,Q14185 17 +Peripheral nervous system myelin maintenance 0.7732379198306598 1.474163452765159 0.1404375874438554 1.0 0.4083343031966626 4 P31751,Q8N3R9 2 +Heart morphogenesis 0.4444942238364693 1.4738429850932544 0.1405238717139347 1.0 0.4083343031966626 34 O94788,P10253,P09493,O96028,O75844 5 +Positive regulation of synapse assembly 0.794950241424709 1.471531031528381 0.1411475617704285 1.0 0.4088293614930491 3 Q9BQT9 1 +Urogenital system development 0.4128632341979751 1.4710581343311098 0.1412753958035411 1.0 0.4088293614930491 47 P46379,P07602,O15078,O94788,O75844 5 +Morphogenesis of an endothelium 0.7105190881625894 1.4699792376987932 0.1415673772503494 1.0 0.4088293614930491 2 P35222 1 +Long chain fatty acid import across plasma membrane 0.7721718792158694 1.4699377265002156 0.1415786206686102 1.0 0.4088293614930491 4 P11166,P31751 2 +Protein localization to perinuclear region of cytoplasm 0.794505494505495 1.469785816322602 0.1416197717927301 1.0 0.4088293614930491 3 Q9UJC3,Q96ED9 2 +Nucleotide transport 0.5024899492519502 1.4672498606578226 0.1423080977283213 1.0 0.4101206120950713 18 Q9BSK2,O00400,Q86VD7,Q8TB61,Q9HC21,P41440 6 +Endocrine hormone secretion 0.7372117061540817 1.4647813353152532 0.1429805857477886 1.0 0.4113469960438322 5 P22466 1 +Regulation of systemic arterial blood pressure mediated by a chemical signal 0.7706262084274053 1.4638096514552024 0.1432459646305357 1.0 0.4113557936286219 4 P42892,P09493 2 +Forebrain development 0.387761003494411 1.4611540406566803 0.1439731725041717 1.0 0.4115372150987972 66 P11166,P07942,Q96N66,O75569,O94788,Q9Y4G8,Q8N3R9,P07196,P05067 9 +Gmp salvage 0.769736735010845 1.460282594435537 0.1442124236540003 1.0 0.4118677148763842 4 P00813 1 +Vascular associated smooth muscle cell migration 0.7918352155609825 1.45930564206824 0.1444810032065859 1.0 0.4122735161040226 3 P09493 1 +Adult locomotory behavior 0.5309555428703086 1.4557917894522217 0.1454501861812067 1.0 0.4132538572767714 16 O75844,P05067,P50897 3 +Regulation of mitophagy 0.6610935333430407 1.453270931223242 0.146148544899104 1.0 0.4138494494954228 7 P21796,P27544 2 +Positive regulation of carbohydrate metabolic process 0.6397924922106488 1.4523675170119137 0.1463994432774935 1.0 0.4141218520888264 8 P31751,P05067 2 +Negative regulation of lipid localization 0.6608648024798398 1.4522532556248866 0.1464311996880196 1.0 0.4141218520888264 7 Q9Y3D6,P31751,Q9BZF1,P31749 4 +Regulation of t cell activation 0.4400196770612071 1.4515004865289067 0.1466405468601379 1.0 0.4142377910313197 35 P00813,Q9HCL2,P30825 3 +Cell maturation 0.4889311382975806 1.4512724330024895 0.1467040143426521 1.0 0.4142377910313197 24 O75503,P05067 2 +Regulation of leukocyte degranulation 0.5869702196203704 1.451059817863228 0.1467632042332916 1.0 0.4142377910313197 11 P51809,P30511,O95219,P11274,Q9NRA0 5 +Lymphocyte mediated immunity 0.4315235044209406 1.4472868741997724 0.1478165937917674 1.0 0.4157458693265288 39 Q9UQ84,Q9NUQ9,Q9BY67,P51809,P02786,P30511,Q9NQT5,P04439,O96028,O15400,P33176 11 +Odontogenesis of dentin containing tooth 0.6587219482973024 1.4427168375163908 0.1491002541404582 1.0 0.4177691309242528 7 Q6P4Q7,P35222,P35221 3 +Purine deoxyribonucleoside monophosphate metabolic process 0.7651489507619289 1.442084002302629 0.1492786775163153 1.0 0.4179175749122726 4 P00813 1 +Damp metabolic process 0.7651489507619289 1.442084002302629 0.1492786775163153 1.0 0.4179175749122726 4 P00813 1 +Aortic valve morphogenesis 0.7870879120879127 1.4406664209851858 0.1496789457425511 1.0 0.4186982354690742 3 O75116,Q13464 2 +Locomotory behavior 0.4573039259953634 1.4397926458579058 0.1499260724468984 1.0 0.4186982354690742 31 O15118,P50897,P80404,P10253,P54802,Q9NWW5,O75844,P05067 8 +Regulation of reactive oxygen species biosynthetic process 0.6145503950365764 1.4393395459461995 0.1500543435530765 1.0 0.4186982354690742 9 Q9NRA0,Q9BSK2,O75027,P51790 4 +Regulation of receptor binding 0.7642189975633646 1.4383938422846687 0.1503223388070516 1.0 0.4192539738264482 4 P10586 1 +Neuromuscular process 0.4622154805982978 1.437735193250975 0.150509203484821 1.0 0.4195995074558001 30 Q8N0X7,O75844,Q7Z406,P10253,O14773,P07196,O75592,P11274,P05067 9 +Chemical synaptic transmission postsynaptic 0.5416355098319615 1.4348863031322687 0.1513194993847615 1.0 0.420454513614537 15 Q9UQB8,P05067 2 +Regulation of postsynaptic membrane potential 0.5416355098319615 1.4348863031322687 0.1513194993847615 1.0 0.420454513614537 15 Q9UQB8,P05067 2 +Somatic diversification of immunoglobulins 0.4922885500019794 1.4312419757333603 0.1523608771784037 1.0 0.4226862838101027 21 Q9UQ84,P20585,P02786,Q9NQT5,O96028 5 +Meiotic chromosome condensation 0.728986475204169 1.4311384128639513 0.1523905500977664 1.0 0.4226862838101027 5 O95347,Q15021,Q9NTJ3 3 +Regulation of mesenchymal cell proliferation 0.7846153846153852 1.4309552488279134 0.1524430411780559 1.0 0.4226862838101027 3 P02545,P35222 2 +Mating 0.7288892932218011 1.430740674026611 0.1525045514452179 1.0 0.4226862838101027 5 P05067 1 +Regulation of chaperone mediated autophagy 0.7844360394782132 1.430250764984929 0.1526450601441142 1.0 0.422899806960596 3 P10619 1 +Positive regulation of mitochondrion organization 0.4791579900948497 1.42810267291183 0.1532623082873436 1.0 0.4240808804479115 26 P21796,Q8N2A8,Q9GZY8 3 +Muscle cell proliferation 0.474807181715323 1.426968308344272 0.1535890296923379 1.0 0.4244561198009321 27 Q9Y5B6,Q53EL6,Q16539,P06493,Q14344,P09601,P17301,P31749,P35222,O95140,Q68CP9,P42224,P12956,P09493,Q8NDZ4 15 +Ether metabolic process 0.6118295458411732 1.4262158698117275 0.1538060401374252 1.0 0.4247035414155261 9 O00116,Q6PIU2,P07099 3 +Myelin maintenance 0.6925558118893191 1.423781656401626 0.1545096873505547 1.0 0.4256392566667635 6 P31751,Q8N3R9 2 +Regulation of ruffle assembly 0.6335471544745696 1.423526358093792 0.1545836267609992 1.0 0.4256392566667635 8 P84095,Q8NCA5 2 +Regulation of smooth muscle contraction 0.7265600632719499 1.4212061984534607 0.155256823241868 1.0 0.4264083876673409 5 P00813 1 +Regulation of isotype switching 0.5810982678838728 1.4207708224181967 0.1553833956560564 1.0 0.4264083876673409 11 Q96FV9,P02786,Q9NQT5,Q96FZ2,O96028 5 +Regulation of b cell mediated immunity 0.5810982678838728 1.4207708224181967 0.1553833956560564 1.0 0.4264083876673409 11 Q96FV9,P02786,Q9NQT5,Q96FZ2,O96028 5 +Arf protein signal transduction 0.7818452720330029 1.4200728238357134 0.1555864810726905 1.0 0.4266142894598095 3 Q15555 1 +Lymphocyte costimulation 0.7590505626893558 1.417877747662339 0.1562264601269409 1.0 0.427138655652773 4 Q9NPF0 1 +Antigen processing and presentation of peptide antigen via mhc class i 0.5518771401029364 1.4159575189940192 0.156787942605149 1.0 0.4277806148081591 14 Q9UIQ6,P30511,Q9NZ08,P10321 4 +Response to nitric oxide 0.6526331724074729 1.4155973609152182 0.1568934244462561 1.0 0.4277806148081591 7 O95831 1 +Cellular response to reactive nitrogen species 0.6526331724074729 1.4155973609152182 0.1568934244462561 1.0 0.4277806148081591 7 O95831 1 +Regulation of vascular permeability 0.6314220950036636 1.413704066418326 0.1574488109012244 1.0 0.428546334573063 8 Q07157,Q96AC1,O94813,Q02952,P11274,Q16625 6 +Neurotransmitter transport 0.4587807761678152 1.411786770008775 0.1580127551202721 1.0 0.4296092025319754 30 P50897,Q4J6C6,P16615,Q7L0J3,P41440 5 +Establishment of endothelial barrier 0.4938840574299372 1.4117189161437138 0.158032741318606 1.0 0.4296092025319754 18 O75116,Q9Y4G8,Q13464 3 +Positive regulation of nik nf kappab signaling 0.5789115831752853 1.409479245672391 0.1586935061461498 1.0 0.4310537429481437 11 P05067,O43707 2 +Dendrite arborization 0.7787159151919198 1.407776291732319 0.1591973227420675 1.0 0.4322460315527286 3 Q13641 1 +Endosome to lysosome transport 0.4825006491729998 1.4070415989573737 0.1594150539080561 1.0 0.4324791949196358 24 Q99523,P20645,Q8WUH2 3 +Positive regulation of regulated secretory pathway 0.6299529232304296 1.4069109276771836 0.1594538028094145 1.0 0.4324791949196358 8 Q9NRA0,P30511,O95219 3 +Neuron projection organization 0.4867010168515001 1.4064720280548015 0.1595840050494996 1.0 0.4324791949196358 22 Q99538,Q9UQB8,P05067,Q14203 4 +Vacuolar transport 0.3839648663736954 1.405650857962022 0.1598278260982861 1.0 0.4328543335958679 65 P11717,Q14108,P20645,Q8WUH2,O15118,P07602,Q99523,Q96ED9,Q14457 9 +Response to radiation 0.3740333169389125 1.405417528365133 0.1598971574700252 1.0 0.4328543335958679 95 P22830,P27544,P05067,Q13432,Q70UQ0,Q13049,O95155,Q15046,Q9P2X3,O60858,P12956,Q13330,O15287,Q9BRK5,Q15555,Q96K76,Q9UNS2,P31751,Q9H2U1,O75844 20 +Glycoprotein metabolic process 0.376217537711261 1.4044955301168571 0.1601713417900259 1.0 0.4332178026334387 78 O15118,Q9HC07,O60476,Q99805,Q8NCH0,Q8WVQ1,Q96L58,Q08379,Q9BXS4,Q6ZXV5,Q92542,O43505,O60858,Q9H9S5,O60502,O60512,P04843,Q9NX62,P15291,Q9NQX7 20 +Manganese ion transport 0.7554870639115798 1.403725962868142 0.160400468121971 1.0 0.4332178026334387 4 Q9HD20 1 +Manganese ion transmembrane transport 0.7554870639115798 1.403725962868142 0.160400468121971 1.0 0.4332178026334387 4 Q9HD20 1 +Regulation of mitochondrial fusion 0.722195709992098 1.4033333648255204 0.1605174532938962 1.0 0.4332227976878331 5 P02786,Q8N2A8 2 +Cellular response to muramyl dipeptide 0.7775726782581611 1.4032833676783767 0.1605323559194447 1.0 0.4332227976878331 3 P08670 1 +Regulation of gtp binding 0.6496566623682452 1.402328646502769 0.1608171298594287 1.0 0.4337139969882447 7 O75503,Q9NWH9 2 +Ameboidal type cell migration 0.3759257235992808 1.402236761238173 0.1608445574903125 1.0 0.4337139969882447 85 P35579,Q15555,P42785,Q06481,Q8WTV0,Q13464,P25705,O75116,P57105,Q13641,P78536,Q14185 12 +Negative regulation of reactive oxygen species metabolic process 0.5698463102019758 1.4006319651925303 0.1613241570795693 1.0 0.4343041853014831 12 O75027,Q14457 2 +Actin filament based transport 0.648601325345479 1.397622482466356 0.1622264633475869 1.0 0.436028610441699 7 Q8WXH0,Q9UH99,O94832,O43707 4 +Striated muscle adaptation 0.686312964516209 1.3972787181013584 0.1623297730192952 1.0 0.4361303538820822 6 Q13555,P16615 2 +Response to purine containing compound 0.5208760797254512 1.39545573522089 0.1628784541458463 1.0 0.4368998148042569 16 P05067 1 +Protein localization to cell junction 0.4849771235864694 1.3948592169579852 0.1630582975198526 1.0 0.4372062118208364 22 Q9Y496,Q9BQT9,Q14168,Q9UQB8,P33176 5 +Immunological synapse formation 0.6932161494094988 1.3927359335816083 0.1636996581575553 1.0 0.4380445069493138 2 P26038 1 +Positive regulation of dendritic cell differentiation 0.6932161494094989 1.3927359335816083 0.1636996581575553 1.0 0.4380445069493138 2 P09429 1 +Cellular response to leucine 0.6926668497665438 1.3902824982503934 0.1644431103258048 1.0 0.4387672493183191 2 Q9P2J5 1 +Positive regulation of calcium ion import 0.7741666386026165 1.3898957238994136 0.1645605442978241 1.0 0.4387672493183191 3 Q9NRA0 1 +Negative regulation of dna biosynthetic process 0.5819083898637427 1.389674466877524 0.164627751630872 1.0 0.4387672493183191 10 Q96TA1,Q9NVN8,Q99543,P27544 4 +Embryonic organ development 0.3906458489520059 1.38945605391518 0.1646941153452072 1.0 0.4387672493183191 57 O15078,O94788,P42892,P54802,Q9Y366,P00813,P11274 7 +Nitric oxide synthase biosynthetic process 0.7739010989010996 1.3888518943635677 0.1648777912102093 1.0 0.4389056024105571 3 P43490,P42224 2 +Positive regulation of nitric oxide synthase biosynthetic process 0.7739010989010996 1.3888518943635677 0.1648777912102093 1.0 0.4389056024105571 3 P43490,P42224 2 +Mirna loading onto risc involved in gene silencing by mirna 0.7737246032568785 1.3881580865054524 0.1650889120505128 1.0 0.4390310040455825 3 O75569 1 +Phosphatidylinositol 3 kinase signaling 0.5671810593541203 1.3865342841503967 0.1655838190379479 1.0 0.4390310040455825 12 Q10713,Q8NDZ4,Q9NZM5,O00443,Q14457,P31749 6 +Antigen processing and presentation of exogenous antigen 0.5810822869376892 1.3854967817714685 0.1659006158842084 1.0 0.4390310040455825 10 Q9UIQ6,Q99538,P30511 3 +Regulation of pattern recognition receptor signaling pathway 0.4792472510959884 1.3846260127424987 0.1661668531537179 1.0 0.4390310040455825 24 Q9NPR9,P41440,Q06481 3 +Positive regulation of myotube differentiation 0.6912936006591556 1.3841487243057615 0.1663129201595241 1.0 0.4390310040455825 2 P42345 1 +Regulation of cardiac muscle cell proliferation 0.6912936006591556 1.3841487243057615 0.1663129201595241 1.0 0.4390310040455825 2 P06493 1 +Positive regulation of cardiac muscle cell proliferation 0.6912936006591556 1.3841487243057615 0.1663129201595241 1.0 0.4390310040455825 2 P06493 1 +Endodermal cell differentiation 0.6250181185489238 1.384079584146386 0.1663340874775827 1.0 0.4390310040455825 8 P07942,Q8N7H5,Q92541,Q6PD62,P35222 5 +Endoderm formation 0.6250181185489238 1.384079584146386 0.1663340874775827 1.0 0.4390310040455825 8 P07942,Q8N7H5,Q92541,Q6PD62,P35222 5 +Gdp metabolic process 0.7505086978873685 1.3839476045819412 0.1663744987565805 1.0 0.4390310040455825 4 Q14168 1 +Segmentation 0.5184716941603337 1.3810348742256793 0.1672682380754344 1.0 0.4405958465671251 16 O94788 1 +Response to mineralocorticoid 0.6447683676067386 1.3805228369198184 0.167425723201898 1.0 0.4405958465671251 7 O95831 1 +Protein targeting to vacuole 0.4862360073634362 1.379965176803426 0.1675973670305617 1.0 0.4405958465671251 20 Q99523,Q14108,P20645 3 +Positive regulation of endothelial cell migration 0.4785220936764068 1.379626515020411 0.1677016692126036 1.0 0.4406136521938399 24 Q8WTV0,Q99538,Q9NWH9,O75116,P25705,P78536,P31749 7 +Regulation of lipid transport 0.4804961139865694 1.378164182168425 0.1681526031370643 1.0 0.4410996798011421 23 P22466,P14174 2 +Striated muscle cell proliferation 0.6436615169530956 1.375582992624468 0.1689507751213643 1.0 0.4424546939055003 7 Q9Y5B6,Q8NDZ4 2 +Intracellular receptor signaling pathway 0.3823072222305599 1.374503906523893 0.1692852983115849 1.0 0.4430220699791923 64 O94788,P42785,Q13573 3 +Histone lysine demethylation 0.6809038728495422 1.3742962688834317 0.1693497241838515 1.0 0.4430220699791923 6 Q8NB78 1 +Interferon gamma production 0.6009440286922549 1.3736317125134896 0.169556046553124 1.0 0.4430399757582218 9 P14373,Q9NUQ9,Q01650 3 +Endosomal transport 0.3719194507107337 1.3719724671169238 0.1700720090887879 1.0 0.4440009008539177 93 Q92538,Q4J6C6,Q9HD42,Q96C92,P14373,O75503,Q9Y5X2,Q07960,Q8IUD2,Q14203,O60499,Q9NZM3,Q8IWJ2,O43752,Q9H223,Q567U6,Q8NBN3,Q15075,Q9Y5X1,O15260,Q99523,Q93009,O95219,O60826 24 +Cellular response to corticosteroid stimulus 0.5566215975160616 1.3713878708570657 0.1702540764748774 1.0 0.4440019801945293 13 P25705,O95831 2 +Semi lunar valve development 0.7468778114543629 1.3695177407722054 0.1708374931270611 1.0 0.4450485778321842 4 O75116,Q13464 2 +Mitochondrion endoplasmic reticulum membrane tethering 0.7468603997383644 1.3694485344649951 0.1708591118257132 1.0 0.4450485778321842 4 P16615,O43865 2 +Intracellular lipid transport 0.516305581405171 1.368034586339322 0.1713012503118629 1.0 0.4458725741352957 16 P23786,O43772,O15118,O14678 4 +Activation of innate immune response 0.4827066433142614 1.3673772667599835 0.1715070841504731 1.0 0.4460389155716636 21 Q9NZI8,Q15233,Q7Z434,Q8WXF1,P12956,P43243,P13010,Q9NUD5,P09429,P23246 10 +Negative regulation of fatty acid transport 0.7673076923076931 1.3629292834836548 0.1729047986805214 1.0 0.4491264895736756 3 P31751,P31749 2 +Regulation of dna methylation 0.6203091489016441 1.3622746651878552 0.1731112199139972 1.0 0.4491589012020887 8 Q8NB78,O75844 2 +Toll like receptor signaling pathway 0.4854375649687524 1.3570552950684471 0.1747636416149092 1.0 0.452486141167375 18 Q9NPR9,P41440,O75955,Q06481 4 +Regulation of chemotaxis 0.4409620234899589 1.354133754410736 0.1756937090237302 1.0 0.4534919867838642 32 Q9NUQ9,Q9NWH9,P14174,Q13641,P78536,Q9BX67,O75592 7 +Intracellular mrna localization 0.684427355122215 1.35347749839602 0.1759031338403502 1.0 0.4537524509400905 2 Q9H2U1 1 +Retinal ganglion cell axon guidance 0.7095429365223332 1.3514696709588017 0.1765450289613974 1.0 0.4544155838678681 5 O94813,Q15375,P83731 3 +Synaptic vesicle exocytosis 0.4833134602602142 1.351293586012443 0.1766014058345477 1.0 0.4544155838678681 19 Q7L0J3,Q4J6C6 2 +Negative regulation of translational initiation 0.6179195030257755 1.3512031339875454 0.1766303709497245 1.0 0.4544155838678681 8 Q06787,P12270,P60228,Q9BPZ3 4 +Regulation of skeletal muscle tissue development 0.7093062323821944 1.350498857813216 0.1768560197997877 1.0 0.4546264120084821 5 P41440,O75955 2 +Positive regulation of myeloid leukocyte mediated immunity 0.6748268735526537 1.3484578694561593 0.1775111620062519 1.0 0.4561345439443335 6 Q9NY93,Q7Z434 2 +Myeloid cell apoptotic process 0.6171469863760144 1.3476231263759384 0.1777796284872654 1.0 0.4565653963597266 8 P14174 1 +Production of molecular mediator involved in inflammatory response 0.5396509325632453 1.3475104837302916 0.1778158792666202 1.0 0.4565653963597266 14 Q8IV08,Q06481 2 +Negative regulation of response to external stimulus 0.3855847815929589 1.345736577005907 0.1783874857965584 1.0 0.4570766924824891 58 P19474,P30511,P14174,P00813,Q9UMX5,Q96G23,P80303 7 +Regulation of cellular component movement 0.3355581600785798 1.3453652601160273 0.1785073082225525 1.0 0.4570766924824891 165 P07942,P42785,Q8WTV0,P84095,P14174,P02545,Q96G23,P05067,Q9UH99,Q06481,P16615,O75116,P00813,O75592,Q13049,P12814,Q13464,O43707,Q9Y4G8,P09493,P78536,P11274,Q14185,Q9NUQ9,Q15555,Q9NWH9,P25705,P57105,P31751,O95684 30 +Cellular response to hormone stimulus 0.3339613478437132 1.343624611664434 0.1790698067010119 1.0 0.4577647145651637 138 Q9BSK2,P42785,O15118,Q06481,P43490,O15173,Q16739,Q13464,Q01664,O95831,P25705,O75116,P31751,Q9P1Z2,Q9NS86,O43865,Q7L576,Q9UQB8 18 +Photoreceptor cell differentiation 0.6161975089960825 1.3432225041565256 0.179199936799844 1.0 0.4578256054054297 8 P54802,Q15555,O15078 3 +Synaptic transmission gabaergic 0.6734837655215882 1.342744937517237 0.1793545783295163 1.0 0.4580450576502748 6 Q13641,Q9BQT9,P33176 3 +Regulation of nitric oxide synthase activity 0.6359778286335458 1.3412692587569457 0.1798330469040117 1.0 0.4585639462385878 7 Q8WTV0 1 +Vitamin d metabolic process 0.7615384615384623 1.340242509548608 0.1801665154325646 1.0 0.4590629033755941 3 Q99538,P04062 2 +Cobalamin transport 0.7606856652709258 1.3368888092501894 0.1812589342203323 1.0 0.4606133786079613 3 O14678 1 +Dendritic transport 0.705618764330882 1.3353730616999535 0.1817542769038116 1.0 0.4615361710558327 5 P33176 1 +Purine ribonucleotide salvage 0.6716155282590706 1.334797148477176 0.1819427470339825 1.0 0.4616468101627667 6 P00813 1 +Histone h3 k36 methylation 0.7054089262690476 1.334512207216263 0.182036048904159 1.0 0.4617077251040775 5 O96028,Q96L73 2 +Foregut morphogenesis 0.6794836583356179 1.3313943780816746 0.1830592782908329 1.0 0.4637733730995512 2 P35222 1 +Regulation of amino acid transport 0.633592437497612 1.3306096954676845 0.1833174706225167 1.0 0.4638903041803133 7 Q7L0J3,P80404 2 +Dna replication checkpoint signaling 0.7370664297748526 1.3305102101764636 0.1833502245723353 1.0 0.4638903041803133 4 O75419 1 +Positive regulation of proteolysis 0.3665319977823529 1.330508975132584 0.1833506312181358 1.0 0.4638903041803133 99 P46379,Q12834,O00291,P05067,P35579,Q9Y4X5,O95831,O75116,Q6ZXV5,Q92542,Q13049,P23396,Q01664,Q96F07,Q9BXK5,Q96HY6,Q9Y5X1,Q96A26,Q9NWW5,O60826 20 +Hindbrain development 0.4178179486439776 1.329755384675793 0.1835988801293913 1.0 0.4638903041803133 39 Q9BRK5,O15078,O94788,Q5KU26,P54802,O95456,Q92542 7 +Bone remodeling 0.613123076211843 1.3289692785373972 0.1838581056405206 1.0 0.4638903041803133 8 Q9UBB6,P02786,O14773 3 +Leptin mediated signaling pathway 0.7364137078286475 1.327914591424853 0.1842063237802262 1.0 0.4638903041803133 4 Q16739 1 +Cellular response to leptin stimulus 0.7364137078286475 1.327914591424853 0.1842063237802262 1.0 0.4638903041803133 4 Q16739 1 +Response to leptin 0.7364137078286475 1.327914591424853 0.1842063237802262 1.0 0.4638903041803133 4 Q16739 1 +Positive regulation of antigen receptor mediated signaling pathway 0.7583840891200457 1.3278375601681291 0.1842317757333131 1.0 0.4638903041803133 3 P00813 1 +Exocytic process 0.4809258449715984 1.327799175412709 0.1842444594399142 1.0 0.4638903041803133 18 Q7L0J3 1 +Photoreceptor cell development 0.6328863287100583 1.3274537604893697 0.184358626064756 1.0 0.4638903041803133 7 P54802,Q15555,O15078 3 +Regulation of skeletal muscle adaptation 0.7579150018246243 1.3259928086100916 0.1848420794274128 1.0 0.4644052696926288 3 Q13555 1 +Skeletal muscle adaptation 0.7579150018246243 1.3259928086100916 0.1848420794274128 1.0 0.4644052696926288 3 Q13555 1 +Metal ion homeostasis 0.3686984260703017 1.3242022689400994 0.1854358775197604 1.0 0.465546063268336 90 Q9NWR8,Q9Y487,P16615,Q9H4I9,P30519,Q7L0J3,Q6P4Q7,Q9HD20,O75027,O60826,Q8IYU8,P05067 12 +Inorganic anion transport 0.4371294260985703 1.323989787687105 0.1855064363805252 1.0 0.4655477911877362 32 Q9UHG3,P21796,P55011,Q9UBX3,P45880,P51790,Q9H813,O43681,Q9Y6M7 9 +Positive regulation of neuron differentiation 0.5688413397514844 1.3235095330310425 0.1856659881701905 1.0 0.4657727707748417 10 Q8WUJ1,Q13049 2 +Toxin transport 0.5352316878804945 1.3227199855905092 0.1859285147294196 1.0 0.4662558124358761 14 Q93050,P78371 2 +Centriole centriole cohesion 0.7018672185292893 1.3199809190894802 0.1868413886886835 1.0 0.4674331428706736 5 Q14203,P35222,Q9Y496 3 +Insulin like growth factor receptor signaling pathway 0.7342855625698064 1.319451481901191 0.1870182202705159 1.0 0.4674331428706736 4 P11717 1 +Positive regulation of glucose transmembrane transport 0.6310185065126355 1.3191044259072704 0.1871342037339032 1.0 0.4674331428706736 7 P31749,P31751,Q9BZF1,Q16625 4 +Immune response regulating signaling pathway 0.3791591255375425 1.3171670520978225 0.187782635304043 1.0 0.4686126213598647 62 Q9NPR9,P00813,P46379,Q06481 4 +Membrane raft assembly 0.6673547032946882 1.316666160214958 0.1879505513715478 1.0 0.4686805852502332 6 P41440 1 +Positive regulation of glucose import 0.6660348973802616 1.3110488390284791 0.189841263849626 1.0 0.4719822168022606 6 P31749,P31751,Q9BZF1,Q16625 4 +Glycosylation 0.3812259046759733 1.3092534502274151 0.1904485120549326 1.0 0.47287158447592 59 O15118,Q08379,Q9HC07,Q96L58,Q10472,O43505,Q96JB2,Q8NAT1,O60476,Q9BXS4,Q6ZXV5,Q9H9S5,O60502,O60512,O75503,P15291,P04843 17 +Amide transport 0.389327640587417 1.3063191677915615 0.1914440414035005 1.0 0.4739652466393795 49 P07602,P22466,Q13555,P53985,P41440 5 +Multi organism reproductive process 0.3352381185961363 1.3049835421459834 0.1918984519508786 1.0 0.4744413303705767 170 Q8NB78,P46379,P54619,P78371,Q15102,P14373,P05067,P55769,P35579,P11717,P11166,Q96CW5,Q9BY67,Q9UIQ6,Q00536,P80404,O75718,Q96GC9,Q9UHI6,P00813,O75592,Q9Y2W6,Q8N2A8,Q15056,Q9BTX1,P45880,O15287,Q9BX67,P41440,Q9NRA0,P31749,Q96PU8,Q9BPZ3,P17655,Q9UJC3,P15291,Q9H2U1,Q96RK4,Q9UPN4,P26583,Q9P0K7,A0AVF1 42 +Positive regulation of response to external stimulus 0.3678932217115673 1.30449998796022 0.1920631636217238 1.0 0.4746724255235704 70 Q15046,Q9BY67,P51809,Q99538,Q7Z434,P30511,Q9NWH9,P14174,Q13641,P12956,O95219,P78536,P05067,P23246 14 +Regulation of viral entry into host cell 0.6642286642374368 1.3033604132720154 0.1924517447966534 1.0 0.4754564240193183 6 P19474 1 +Cell death in response to oxidative stress 0.4531757911549183 1.3010733720670906 0.1932333412727129 1.0 0.4768569455185505 28 Q99720,P23246,Q15233,Q07820,Q9NWH9,P35222,Q15118,P04062,P31749 9 +Antigen processing and presentation of endogenous peptide antigen 0.5858568096291384 1.300577908573966 0.1934029728097175 1.0 0.4770988551762858 9 P30511,Q9NZ08,P10321 3 +Cell adhesion molecule production 0.7294833922754765 1.300353301922491 0.1934799072712287 1.0 0.4771119993146548 4 P41440,O75955 2 +Regulation of biomineralization 0.5857329130756832 1.299977334415734 0.1936087376241964 1.0 0.4772530591158049 9 O75116,O75844 2 +Response to fluid shear stress 0.6723427629771994 1.2995025624598875 0.1937715146432248 1.0 0.477477663486615 2 P31749 1 +Regulation of system process 0.370128277366296 1.2974197162217298 0.1944868122770842 1.0 0.4780028145341984 68 P09493,P22466,Q13555,O75844,P16615,P02545,O75116,P10253,P42892,Q14457,P00813,Q9UQB8,P05067 13 +Response to organic cyclic compound 0.3425097549413533 1.2949534329904506 0.1953362940913316 1.0 0.4788542043894566 189 O15118,P07099,O94788,Q5KU26,Q9P1Z2,Q13126,Q9NY93,P05067,P16278,Q7Z434,P49321,P53985,O95831,O75116,O75592,Q92542,P49721,Q14457,O15173,Q01664,Q9Y4G8,Q13573,P41440,P25705,O75955,Q96HY6,P07196 27 +Endothelial cell chemotaxis 0.6947394289306509 1.2907296624885178 0.1967974352203951 1.0 0.4815055223302009 5 Q9NWH9 1 +Hormone transport 0.4065531307701394 1.2891549831769424 0.1973442116712189 1.0 0.4819962474138278 42 O95563,P22466,P51809,Q96TA1,Q13555,P80404,P53985,Q01650,O95219,Q9BRT2,O14523 11 +Presynapse organization 0.6608785441628185 1.2890981898210194 0.1973639528019808 1.0 0.4819962474138278 6 P05067 1 +Ceramide biosynthetic process 0.5412569220320026 1.2879326064769052 0.197769423935781 1.0 0.482286368641336 13 P27544,Q16739,O60512,P04062,Q96G23,Q9NRA0 6 +Antigen processing and presentation of exogenous peptide antigen via mhc class ii 0.6695962647624233 1.2872398747688676 0.1980106928831686 1.0 0.482286368641336 2 Q99538 1 +Positive regulation of t cell mediated immunity 0.6238610604355187 1.2870965503649503 0.1980606376765985 1.0 0.482286368641336 7 Q9NUQ9,P30511,P04439 3 +Modification of postsynaptic actin cytoskeleton 0.7260423593146984 1.2866681295132285 0.1982099860397559 1.0 0.482286368641336 4 Q9UQB8 1 +Mitochondrial fusion 0.5021959477509135 1.2831802274181234 0.1994289415363961 1.0 0.4835498680702356 16 O60313,Q8N2A8,P02786,Q9GZY8,O95140,Q9Y4W6,Q9H300,Q9Y6C9,Q9NX63 9 +Immune response 0.3574734343871658 1.281147663176328 0.200141805077463 1.0 0.4846800395629118 234 Q92538,Q07666,P23246,P46379,P30511,P14174,Q01650,Q5KU26,P14373,Q8TCT8,Q9NY93,P05067,Q9UQ84,P19474,P10321,Q06481,Q9BY67,Q9Y487,P28070,P02786,Q7Z434,Q9NPR9,P00813,O43657,Q13049,P33176,P23396,Q15046,Q15233,O60858,P12956,P04439,O96028,O15400,P41440,P78536,P11274,Q9NRA0,Q9BX67,Q9NUQ9,O00584,P08670,O75569,P51809,Q9NZ08,Q9NQT5,O95219,O75955,Q9H2U1,P26583,P49770 51 +Regulation of short term neuronal synaptic plasticity 0.6682230156550352 1.2811094845681643 0.2001552129065831 1.0 0.4846800395629118 2 Q15042 1 +Positive regulation of nervous system process 0.6923741423465878 1.2810217613413473 0.2001860226440242 1.0 0.4846800395629118 5 P04062,P80404 2 +Head development 0.3341224327576021 1.2801059396745542 0.2005078799959398 1.0 0.4849575749627284 171 P07942,P46379,P28370,O94788,Q15102,Q96N67,Q5KU26,Q8N3R9,P54802,O75503,Q9UQB8,P05067,P11166,Q9BY67,P80404,O75787,Q15375,Q92542,O15078,P50897,Q9Y4G8,P11274,Q9NRA0,Q9BRK5,Q96N66,O75569,Q9BSJ2,Q96RK4,O95456,P07196 30 +Regulation of presynapse organization 0.6920833743752426 1.2798283367424412 0.2006055156273678 1.0 0.4849907658291552 5 P05067 1 +T cell mediated immunity 0.5469289101068836 1.2791487566022692 0.2008446769598804 1.0 0.4852375995367488 12 Q9NUQ9,P30511,P04439,Q9BY67 4 +Positive regulation of peptidase activity 0.4030191952624647 1.2789111883348785 0.2009283322642949 1.0 0.4852430148158744 43 P23396,Q01664,Q96A26,O95831,O75116,Q96F07,Q9BXK5,O00291,Q96HY6,Q99538,Q92542,P05067 12 +Positive regulation of interferon gamma production 0.6582755855621324 1.2780153018829103 0.2012440309433116 1.0 0.4856533785495421 6 P14373,Q9NUQ9,Q01650 3 +Response to molecule of bacterial origin 0.4116443189814411 1.2766453914481852 0.2017274688732273 1.0 0.4866437817169854 39 Q8WTV0,Q9NUQ9,P08670,P14174 4 +Cellular response to oxidised low density lipoprotein particle stimulus 0.6668497665476469 1.274979812611691 0.2023163873789677 1.0 0.4873586728510708 2 P31749 1 +Negative regulation of lymphocyte migration 0.6668497665476469 1.274979812611691 0.2023163873789677 1.0 0.4873586728510708 2 P31749 1 +Small gtpase mediated signal transduction 0.3607257249518918 1.2733830751689008 0.2028821401971365 1.0 0.488368388776561 102 P84095,Q86VI3,Q96N67,Q07960,Q15392,O75116,Q9UBT7,Q02818,Q13464,Q9Y4G8,Q7L576,P41440,P11274,P80303,Q14185,Q9NUQ9,Q15555,Q9NWH9,P57105,O75955 20 +Amp salvage 0.69032906228002 1.272627917123085 0.2031501073006894 1.0 0.4887749900434598 5 P00813 1 +Regulation of intrinsic apoptotic signaling pathway 0.377688060704843 1.2724936829490885 0.2031977671349818 1.0 0.4887749900434598 59 P23396,O60313,Q96K76,Q15233,O75569,Q8N2F6,Q07820,Q8WUK0,Q7LG56,P45880,P14174,Q9H300,Q13049,Q14457,P23246 15 +Protein localization to membrane raft 0.6901483723469719 1.271886289361268 0.2034135239619057 1.0 0.4891173981083283 5 P41440 1 +Regulation of embryonic development 0.4709125024127926 1.2699933883970174 0.2040869852632731 1.0 0.4898528756517252 19 Q96TA1,Q9H2U1,P46379 3 +Regulation of lymphocyte mediated immunity 0.4623505957961068 1.2678729335059966 0.204843331301574 1.0 0.491314296782717 24 Q9NUQ9,Q9BY67,P02786,P30511,Q9NQT5,P04439,O96028,O15400 8 +Mitotic spindle midzone assembly 0.6886607038766845 1.26578028178494 0.2055917564805773 1.0 0.4925774445990963 5 O95239,O43663 2 +Actin mediated cell contraction 0.5241119650613109 1.2602493893814948 0.2075794110713062 1.0 0.4959738644779555 14 P16615,Q9UM22,P09493 3 +Locomotor rhythm 0.7408092162385428 1.2587358080123636 0.2081257730875674 1.0 0.4968620659557369 3 P54802 1 +Negative regulation of lipid transport 0.6532742481528947 1.256718196980269 0.2088556964697874 1.0 0.4980692575440922 6 Q9Y3D6,P31751,P31749 3 +T cell activation 0.3752107291123555 1.2554899918659843 0.2093009389626794 1.0 0.4981460848661418 60 P35579,P23396,Q9NUQ9,Q9HCL2,P26038,Q9BY67,P02786,Q92542,P30825,P04439,P00813,Q9Y6D9,P24390,P78536 14 +T cell proliferation 0.4506649761189201 1.2529719957269958 0.2102158984490403 1.0 0.4988911237488118 27 P23396,P26038,Q9HCL2,Q9BY67,P02786,Q92542,P30825,Q9Y6D9 8 +Myeloid dendritic cell cytokine production 0.6853678412229627 1.252265316464525 0.210473202590111 1.0 0.4988911237488118 5 Q9NY93,Q7Z434 2 +Positive regulation of dendritic cell cytokine production 0.6853678412229627 1.252265316464525 0.210473202590111 1.0 0.4988911237488118 5 Q9NY93,Q7Z434 2 +Dendritic cell cytokine production 0.6853678412229627 1.252265316464525 0.210473202590111 1.0 0.4988911237488118 5 Q9NY93,Q7Z434 2 +Transposition 0.7390109890109898 1.2516687823863994 0.210690579830544 1.0 0.4990513094244277 3 Q9HCE1,Q5TAX3 2 +Regulation of transposition 0.7390109890109898 1.2516687823863994 0.210690579830544 1.0 0.4990513094244277 3 Q9HCE1,Q5TAX3 2 +Regulation of t cell mediated immunity 0.5952773809663892 1.2461469452966192 0.2127104526391008 1.0 0.5015179568062027 8 Q9NUQ9,P30511,P04439 3 +Entry of bacterium into host cell 0.7155812036273437 1.2450696130604193 0.213106162708073 1.0 0.5020956018825639 4 Q9BTY2,Q96KP1,Q9UPT5 3 +Regulation of entry of bacterium into host cell 0.7155812036273437 1.2450696130604193 0.213106162708073 1.0 0.5020956018825639 4 Q9BTY2,Q96KP1,Q9UPT5 3 +Regulation of neurotransmitter levels 0.4163516226885663 1.243941776167364 0.2135209924964991 1.0 0.502895147756866 34 P50897,Q4J6C6,P16615,Q7L0J3,P41440 5 +Motor neuron axon guidance 0.614029596687705 1.2431064997470047 0.2138285909576356 1.0 0.503241641751383 7 P84095 1 +Mitophagy 0.4954484275540879 1.2425155156733332 0.2140464194724143 1.0 0.5034208587873973 16 Q5THJ4,P21796,P27544,O95140,Q14457 5 +Negative regulation of ubiquitin dependent protein catabolic process 0.4529699558479702 1.242296683395374 0.2141271186006506 1.0 0.5034329538589044 26 P46379,Q9H2J4,Q96HY6 3 +Attachment of spindle microtubules to kinetochore 0.4673863704191627 1.2398105822918215 0.2150454631691005 1.0 0.505413728781558 18 Q8NBT2,Q96DB5,Q96EE3,Q9Y448,Q9HC35,Q9Y6D9,Q14457 7 +Secretion 0.3347632117799626 1.2357459151320318 0.2165530245673173 1.0 0.5080608460183222 179 Q4J6C6,P30511,P14174,Q7L0J3,Q13505,O95563,P20645,P22466,P53985,P16615,P00813,O75592,Q16850,P50897,Q9NRA0,Q9BRK5,P35580,Q13555,Q9UNS2 19 +Positive regulation of dna ligation 0.6577863224388856 1.2345465918617975 0.216999296410552 1.0 0.5087495819787151 2 P09429 1 +Cytoskeleton dependent intracellular transport 0.3669888094391223 1.234271081476077 0.2171019080515774 1.0 0.5088111197142668 66 Q9Y496,Q8TD16,Q9Y366,P05067,O60313,Q9UH99,Q14203,Q96ED9,Q9NXR1,O43805,Q5SNT2,P33176,O43707,Q14168,Q9Y678,O95239,Q9UPN4,P07196,P23246,A0AVF1 20 +Positive regulation of cold induced thermogenesis 0.5383404485224332 1.2335046994988117 0.2173875244674279 1.0 0.5091223464064929 12 Q06481 1 +Membrane to membrane docking 0.7337912087912097 1.2311610497551106 0.2182626359806265 1.0 0.5109117111636688 3 Q13464,P26038 2 +Positive regulation of isotype switching 0.5714804071775439 1.2308429911626622 0.2183815928852062 1.0 0.5109117111636688 9 O96028,P02786,Q96FZ2,Q9NQT5 4 +Positive regulation of b cell mediated immunity 0.5714804071775439 1.2308429911626622 0.2183815928852062 1.0 0.5109117111636688 9 O96028,P02786,Q96FZ2,Q9NQT5 4 +Pyrimidine containing compound transmembrane transport 0.7335658255477924 1.2302757789755434 0.2185938511823082 1.0 0.5112287927089223 3 Q9BSK2 1 +Second messenger mediated signaling 0.4471717064933447 1.2277151917462246 0.2195539015341321 1.0 0.5127541696186197 27 P00813,Q9Y4G8,P16615,P22466 4 +Molting cycle 0.5371116749561539 1.2269710562630922 0.2198334697163155 1.0 0.5130474286234012 12 P22466 1 +Magnesium ion transport 0.6780456783057096 1.222217196162678 0.2216255026124232 1.0 0.5163965789731358 5 Q8N4V1 1 +Regulation of long chain fatty acid import across plasma membrane 0.7306893725177389 1.2189793764929189 0.2228520202130295 1.0 0.5187846962972361 3 P31751 1 +Nucleotide transmembrane transport 0.5355688311341197 1.2187665652547484 0.2229328049909522 1.0 0.5187846962972361 12 Q9BSK2,Q86VD7,P41440,Q8TB61 4 +Membrane docking 0.4237235079118659 1.2183344799512446 0.2230968923550049 1.0 0.5188462805449906 32 O60499,P26038,O15078,P16615,Q13464,Q96GC9,O43752,O43865 8 +Positive regulation of cell cycle phase transition 0.3859375652749127 1.217630989131121 0.2233642326912028 1.0 0.5191671509995578 47 Q96FV9,P31749,Q7L2J0,Q7LG56,Q9UJX3,P31350,Q9NYL9,Q13769,P78536,Q96DY7,P05067,Q8N7H5,Q96HY6 13 +Positive regulation of calcineurin mediated signaling 0.6536665751167212 1.216184217117722 0.2239147546191318 1.0 0.5196762533351096 2 Q8IWX8 1 +Regulation of lymphocyte differentiation 0.5279926941771901 1.215721306893487 0.2240911047197178 1.0 0.5196762533351096 13 P00813 1 +Carbohydrate mediated signaling 0.7081615828524273 1.2155791258434392 0.2241452898850862 1.0 0.5196762533351096 4 Q12824,P17480,Q5KU26 3 +Somatic diversification of immunoglobulins involved in immune response 0.4903339813509972 1.2116668083842783 0.2256399494942769 1.0 0.5216651573491905 16 O96028,Q9UQ84,P02786,Q9NQT5 4 +Immunoglobulin production involved in immunoglobulin mediated immune response 0.4903339813509972 1.2116668083842783 0.2256399494942769 1.0 0.5216651573491905 16 O96028,Q9UQ84,P02786,Q9NQT5 4 +Intestinal hexose absorption 0.6525679758308107 1.211289673497168 0.2257844050374031 1.0 0.5218180682498152 2 P15311 1 +Purine nucleotide salvage 0.60643835426077 1.209132917794342 0.226611784497827 1.0 0.5233671820135257 7 P00813 1 +Regulation of transmission of nerve impulse 0.7280219780219789 1.2085073346151078 0.2268521762534294 1.0 0.5237408351963272 3 P04062,P17301 2 +Mesenchymal cell proliferation 0.7060057043290604 1.2070135456178088 0.2274269274077129 1.0 0.5247665359716335 4 P02545,P35222 2 +Response to muramyl dipeptide 0.6743227076189379 1.206943345753171 0.227453963062596 1.0 0.5247665359716335 5 P08670,Q9NZZ3 2 +Response to peptide 0.3539102011310864 1.2043319409055562 0.2284613059352811 1.0 0.5259978166713125 105 Q9BSK2,P11166,P22466,Q06481,P43490,P08670,Q13464,Q99523,O75116,P07196,O43865,Q7L576,Q9UQB8,P05067 14 +Purine deoxyribonucleotide metabolic process 0.6407159127196127 1.2032420252220146 0.2288826765375882 1.0 0.5266912561187549 6 P00813 1 +Regulation of phosphatidylinositol 3 kinase signaling 0.5655197543164916 1.201913012519384 0.2293972323109581 1.0 0.5266912561187549 9 Q8NDZ4 1 +Mammalian oogenesis stage 0.6503707772589897 1.2015034726208431 0.2295559602451997 1.0 0.5266912561187549 2 Q96MU7 1 +Positive regulation of neuron apoptotic process 0.5855922448386465 1.2011658847683946 0.2296868600163106 1.0 0.5266912561187549 8 Q15375,Q07820,O95831 3 +Synaptic vesicle endosomal processing 0.6727852412409355 1.200636896806086 0.2298920820026277 1.0 0.5266912561187549 5 Q15075,Q9NZM3 2 +Cranial nerve development 0.6726717024704614 1.200171208564034 0.2300728546424801 1.0 0.5266912561187549 5 Q9H061,P35222 2 +Myeloid leukocyte mediated immunity 0.4602728800432085 1.200079394770374 0.2301085071977808 1.0 0.5266912561187549 19 P51809,Q7Z434,O95219,P78536,Q9NY93,P11274,Q9NRA0 7 +Negative regulation of vascular permeability 0.7258241758241766 1.199881559726894 0.2301853426111082 1.0 0.5266912561187549 3 Q02952,O94813 2 +Positive regulation of lymphocyte migration 0.7039230612109822 1.1987406711810884 0.2306287982444754 1.0 0.5273437483537886 4 P05067 1 +Positive regulation of t cell migration 0.7039230612109822 1.1987406711810884 0.2306287982444754 1.0 0.5273437483537886 4 P05067 1 +Regulation of secretion 0.3470797850425171 1.1951162898008807 0.2320415983286636 1.0 0.5289405301621232 115 O95563,Q16850,P35580,P22466,Q4J6C6,P53985,P30511,P16615,P14174,Q7L0J3,P00813,O75592,Q9NRA0 13 +Cellular response to oxygen levels 0.4001516442717255 1.1944975943112086 0.2322833811890614 1.0 0.5289435913275571 40 Q9Y487,Q96A26,O95831,P02545,P55786 5 +3 utr mediated mrna destabilization 0.6385264195457803 1.1939210015739008 0.2325088714386689 1.0 0.5289435913275571 6 Q9H2U1,Q9HCE1,Q92945 3 +Platelet morphogenesis 0.6384964473548833 1.1937934135061228 0.2325587887561107 1.0 0.5289435913275571 6 P35579 1 +Plasma membrane to endosome transport 0.7018884766184061 1.1906605099478138 0.2337868865760921 1.0 0.531101952013809 4 Q99523,P61020 2 +Ruffle organization 0.4734645656478036 1.1897468952948371 0.2341458875540036 1.0 0.5317362129421699 17 P84095,Q8NCA5,P09493 3 +Positive regulation of stress activated protein kinase signaling cascade 0.5298318902343347 1.188252422182155 0.2347339761337226 1.0 0.5323435864540377 12 P05067,O15344 2 +Positive regulation of hydrogen peroxide mediated programmed cell death 0.6473496292227359 1.188054198913759 0.2348120572717325 1.0 0.5323435864540377 2 Q14249 1 +Response to vitamin 0.4731613397637862 1.1878474015056664 0.2348935354070045 1.0 0.5323435864540377 17 O94788,Q13573 2 +Regulated exocytosis 0.3904610120345795 1.1872011196251948 0.2351482993686464 1.0 0.5323435864540377 44 P35579,Q9BRK5,Q4J6C6,P16615,P30511,Q7L0J3,O95219,P11274,Q9NRA0,O14936 10 +Protein o linked glycosylation 0.4591419331859521 1.1861311314141414 0.2355705180279228 1.0 0.5328632487103111 18 Q10472,O43505,Q8NAT1,Q6ZXV5,Q9H9S5,O60502 6 +Regulation of spontaneous synaptic transmission 0.7221296694651469 1.1853876581546148 0.2358642092014684 1.0 0.5328632487103111 3 P05067 1 +Spontaneous synaptic transmission 0.7221296694651469 1.1853876581546148 0.2358642092014684 1.0 0.5328632487103111 3 P05067 1 +Positive regulation of neuron death 0.4727328071886137 1.1851628758886836 0.2359530549892787 1.0 0.5328632487103111 17 Q15375,P17655,O95831 3 +Cellular response to chemical stress 0.3570621069139977 1.1848375281895251 0.2360816914592283 1.0 0.5328632487103111 91 P23396,P11166,Q99720,O75569,Q8N0U8,P16615,Q9NWH9,O95831,P39210,P09493,Q9BPX6,P00390,Q14457,P23246 14 +Positive regulation of epithelial cell proliferation 0.4411269700313636 1.1839848078187172 0.2364190767007423 1.0 0.5334440596197244 27 P07942,P09601,Q86VI3,P15291,Q9H2J4,P78536,P26583,P31749 8 +Histone h2a phosphorylation 0.6684966074364214 1.1830499709537032 0.2367893435628496 1.0 0.5339056837315312 5 Q13043,O75844,Q9UIG0 3 +Positive regulation of gene expression 0.3532418508024 1.1824630931840583 0.2370220013653576 1.0 0.5339056837315312 240 P54619,P26038,P98175,P51114,O94788,Q86VI3,P30511,P14174,Q01650,P02545,Q567V2,Q9P1Z2,P14373,Q9BRT2,Q9NY93,P05067,Q16625,P35579,Q9BY67,P02786,Q7Z434,O75787,O75116,Q9H2J4,Q13049,P23396,Q9P2X3,Q8WXW3,Q13464,Q13573,O96028,P78536,P41440,Q9Y2R0,Q9NRA0,Q9NWS8,Q9NUQ9,Q96PU8,Q96E39,P08670,Q8NCA5,Q01082,Q9H2U1,O75955,Q96HY6,O75844 46 +Regulation of tumor necrosis factor mediated signaling pathway 0.5815558896796735 1.1824203739401564 0.237038942995523 1.0 0.5339056837315312 8 Q8TCT8,Q13049 2 +Somatic diversification of immune receptors 0.4408037198072081 1.1816455960867964 0.2373463535041082 1.0 0.5342698491209031 27 Q9UQ84,P20585,P02786,Q9NQT5,O96028,P26583 6 +Aminoglycan metabolic process 0.4561644206084733 1.1806776313790914 0.2377308108741065 1.0 0.5349545399710137 20 P16278,Q8NCH0,P04066,Q9NX62,Q96L58,P15586,O43505,P54802,Q9NWW5 9 +B cell mediated immunity 0.4572687715506942 1.1803219903135111 0.2378721752420842 1.0 0.5350919323558432 19 Q9UQ84 1 +Regulation of mitochondrial fission 0.5280390481437263 1.1787151770010544 0.2385116101515589 1.0 0.5361683058164094 12 Q9NUQ9 1 +Heart valve morphogenesis 0.6667427742335088 1.1758599527495457 0.2396508442125013 1.0 0.5378220191943067 5 O75116,Q13464 2 +Single fertilization 0.4488159936519335 1.174072017957164 0.2403661804183576 1.0 0.5392457441506792 24 P35579,Q96CW5,P45880,P15291,P55769 5 +Response to bacterium 0.3635952460200163 1.1727918833313316 0.2408792738361291 1.0 0.5399724741764382 64 Q9NUQ9,Q8WTV0,P08670,P14174,Q9BTY2,P78536,Q9UQB8 7 +T cell migration 0.5391534255386727 1.1727491794722242 0.24089640334397 1.0 0.5399724741764382 10 P78536,P55011,P05067 3 +Positive regulation of natural killer cell mediated immunity 0.6972113975298238 1.1720936115136258 0.2411594745292538 1.0 0.5401161609372834 4 P30511 1 +Positive regulation of natural killer cell mediated cytotoxicity 0.6972113975298238 1.1720936115136258 0.2411594745292538 1.0 0.5401161609372834 4 P30511 1 +Protein polyubiquitination 0.3715068544697378 1.1718422692043498 0.2412603886649582 1.0 0.540160608089589 53 P19474,O95155,P52888,Q9UIQ6,P14373,Q13049,P55786 7 +Spindle midzone assembly 0.5979595307604676 1.1711936317502816 0.2415209544695171 1.0 0.5405623512362757 7 O95239,O43663 2 +Snorna localization 0.7166750778475026 1.1640044273503831 0.2444222175718835 1.0 0.5440515165309654 3 Q8WWY3 1 +Rhythmic behavior 0.6939162735113409 1.1590200512153013 0.2464480119616867 1.0 0.5470610550232707 4 P54802 1 +Negative chemotaxis 0.7153846153846163 1.1589485548004024 0.2464771555125107 1.0 0.5470610550232707 3 Q15375,O94813 2 +Response to oxidative stress 0.346373503601156 1.157964898435644 0.2468783612194554 1.0 0.5477690711972132 112 Q99720,P30519,O43169,P39210,P00390,P05067,P28074,P16615,Q15392,O95831,Q14457,P23396,Q9P2X3,Q8N0U8,Q7LG56,P09493,O75569,P17655,Q9NWH9,Q15165,P23246 21 +Leukocyte cell cell adhesion 0.3917453593886843 1.1573328521767063 0.247136396360116 1.0 0.5481554962483205 42 P23396,Q9NUQ9,Q9HCL2,P26038,P02786,Q13464,P30825,P04439,P00813,Q9Y6D9 10 +Postsynaptic cytoskeleton organization 0.6617349193406273 1.1553379217246922 0.2479520725150761 1.0 0.5494195740498676 5 P07196,Q16352 2 +Positive regulation of t cell proliferation 0.5298547579914961 1.155016024237159 0.2480838645072089 1.0 0.5495288527963875 11 Q9HCL2 1 +Organic hydroxy compound transport 0.3973594208967384 1.153521938368237 0.2486962182199552 1.0 0.5503411836595348 39 Q8WTV0,P53985,P22466 3 +Amino acid import across plasma membrane 0.5935413089531709 1.1514316112650516 0.2495547152237427 1.0 0.5511379077016234 7 P30825 1 +Fucosylation 0.6388354847569295 1.150200328613861 0.2500613709238335 1.0 0.5517711470527724 2 Q9Y2G5 1 +Protein o linked fucosylation 0.6388354847569295 1.150200328613861 0.2500613709238335 1.0 0.5517711470527724 2 Q9Y2G5 1 +Pyridine containing compound metabolic process 0.5226658316922386 1.1501310995303666 0.2500898790483825 1.0 0.5517711470527724 12 Q13126 1 +Positive regulation of pattern recognition receptor signaling pathway 0.5345080995802097 1.1491418091661951 0.2504975109454617 1.0 0.5524875588975873 10 P41440 1 +Intraciliary transport 0.5542953021043047 1.147437765988832 0.2512007402465155 1.0 0.553672025227434 9 Q9Y366,O43805,Q9UPN4 3 +Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules 0.7121636864701824 1.1463349079618923 0.2516566043853454 1.0 0.5540058440850163 3 O00192 1 +Meiotic spindle assembly 0.7120879120879129 1.1460382634529829 0.2517793202066114 1.0 0.5540164769357273 3 Q12768,Q08379 2 +Secondary alcohol metabolic process 0.3698127657584882 1.1457732045272595 0.2518890050106908 1.0 0.5540164769357273 50 Q16850,P49748,O15118,Q8WTV0,P61916,Q15392,Q9NWW5,Q9UBM7,P48735,P05067 10 +Positive regulation of sequestering of triglyceride 0.637736885471019 1.1453218581433044 0.2520758546371577 1.0 0.5540164769357273 2 O60664 1 +Kinetochore assembly 0.6270876149479145 1.1452506276667451 0.2521053516537783 1.0 0.5540164769357273 6 Q9BS16 1 +Ear development 0.4276235104027592 1.142850793338016 0.2531005456523834 1.0 0.5549937076245074 29 O15078,P42892,P39210,P54802,P11274,Q9Y6M7 6 +Regulation of metaphase plate congression 0.6264104731679156 1.1423713507137154 0.2532996945649297 1.0 0.5549937076245074 6 Q14457 1 +Negative regulation of response to dna damage stimulus 0.4274770217287058 1.141754835829858 0.2535559403450493 1.0 0.5553725281127757 29 P23396,Q96K76,Q96FV9,P14174,Q9BRJ7,Q13049 6 +Telomere maintenance via recombination 0.6583287520615476 1.1413875590608291 0.2537086795543253 1.0 0.5555244600297303 5 Q8IY18,Q92878,Q96SB8,Q9Y3C4 4 +Protein acetylation 0.3634262940702967 1.1405581368368962 0.2540538465960527 1.0 0.5557323637129018 61 P46379,Q8IY18,Q9UPT9,Q9NRA0,Q6N069 5 +Regulation of camp dependent protein kinase activity 0.6259241305477644 1.1403035290220436 0.254159868083581 1.0 0.555781818523433 6 Q9Y4G8,P13861 2 +Positive regulation of autophagy of mitochondrion 0.6255920069315164 1.1388914899379392 0.2547484155193535 1.0 0.5567034085291744 6 P21796,P27544 2 +Trophectodermal cell differentiation 0.6254017940459304 1.1380828196668686 0.2550859013116895 1.0 0.5567107779043134 6 P00813,O75175 2 +Tumor necrosis factor superfamily cytokine production 0.4434614321262937 1.1369330706733272 0.255566265927557 1.0 0.5567107779043134 24 Q9NRA0,P14373,P05067,P14174 4 +Cell proliferation in forebrain 0.6883176153078026 1.136823277647764 0.2556121702674507 1.0 0.5567107779043134 4 Q96N67,Q86VS8 2 +Positive regulation of cytokine production involved in inflammatory response 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.5567107779043134 2 O60684 1 +T helper cell lineage commitment 0.6358143367206754 1.136788127758621 0.2556268676072144 1.0 0.5567107779043134 2 P42345 1 +Radial glial cell differentiation 0.6358143367206754 1.136788127758621 0.2556268676072144 1.0 0.5567107779043134 2 P19022 1 +Positive t cell selection 0.6358143367206754 1.136788127758621 0.2556268676072144 1.0 0.5567107779043134 2 P42345 1 +Cd4 positive or cd8 positive alpha beta t cell lineage commitment 0.6358143367206754 1.136788127758621 0.2556268676072144 1.0 0.5567107779043134 2 P42345 1 +Pancreas development 0.4777900290190238 1.13595425222581 0.2559757109912239 1.0 0.5567107779043134 16 O94788,Q5T9L3,P31749,Q9NWH9,P19022,Q15382,P35222 7 +Establishment of protein localization to endoplasmic reticulum 0.4377367387329111 1.1338037269926675 0.2568768873075737 1.0 0.5578783246839517 26 P46379 1 +Hydrogen sulfide metabolic process 0.7086594607350802 1.1326214982336802 0.2573732366339967 1.0 0.5585525231839594 3 P32929 1 +Amino sugar catabolic process 0.7082788903566313 1.1311328211592864 0.2579991918671513 1.0 0.5594040401597232 3 Q9UJ70 1 +Neuron projection extension involved in neuron projection guidance 0.708004165081906 1.1300582594904354 0.2584516764223248 1.0 0.5599780173243774 3 O94813 1 +Sugar mediated signaling pathway 0.7079670329670339 1.1299130260182173 0.2585128746036351 1.0 0.5599780173243774 3 Q12824,P17480 2 +Negative regulation of calcium ion dependent exocytosis 0.6341664377918099 1.1294772881859625 0.2586965451852705 1.0 0.5599780173243774 2 O00186 1 +T cell proliferation involved in immune response 0.6336171381488547 1.12704114526228 0.2597250851682369 1.0 0.5609556701704903 2 P62753 1 +Regulation of dendritic spine development 0.5001453403318799 1.125355812620643 0.2604382876807549 1.0 0.5615441198522387 14 Q14012,Q9UQB8 2 +Sperm motility 0.6223676188820044 1.125186315870567 0.2605100905844524 1.0 0.5615441198522387 6 Q00796 1 +Cytosolic transport 0.351757893840964 1.1213272014548323 0.2621486110311484 1.0 0.5645430495476864 77 Q92538,P26038,Q4J6C6,Q8N2H4,P14373,O14976,O75503,Q9Y5X2,P42566,Q8IUD2,Q14203,Q96ED9,Q14457,P33176,O60499,Q8IWJ2,O43752,O60749,Q8NBN3,Q15075,O15260,Q99523,Q9UJC3,Q93009 24 +Negative regulation of cyclic nucleotide phosphodiesterase activity 0.6319692392199887 1.1197352035346693 0.262826618732253 1.0 0.5656375195778429 2 Q15043 1 +L alpha amino acid transmembrane transport 0.5223445742969817 1.1159906398840818 0.2644261412084274 1.0 0.5680425020123839 11 Q9Y619,Q15758,P30825,Q01650 4 +T cell cytokine production 0.7043647076907896 1.1158295141860723 0.2644951177031907 1.0 0.5680425020123839 3 P30511 1 +Terpenoid metabolic process 0.4472869725426773 1.1146518325613513 0.2649996494886597 1.0 0.5686963530846076 19 O94788 1 +Early endosome to golgi transport 0.5669414846600913 1.1145887157923526 0.2650267081176682 1.0 0.5686963530846076 8 O15260,O60749,O60499,Q9Y5X2 4 +Positive regulation of mitophagy in response to mitochondrial depolarization 0.7038461538461549 1.1138032281976296 0.265363611768294 1.0 0.5686963530846076 3 Q16543,O95140 2 +Regulation of t cell proliferation 0.446072316187439 1.113618602818872 0.2654428422772219 1.0 0.5686963530846076 20 Q9HCL2 1 +Muscle cell differentiation 0.350216781091817 1.1134170874116025 0.2655293396026372 1.0 0.5686988073842404 73 P35579,Q14012,P12814,Q96PU8,Q8IV08,Q96TA1,P17655,O75844,P16615,O43707,P02545,Q99523,Q7Z4V5,O75955,P09493,P41440,P32929,Q13049 18 +Regulation of nervous system development 0.3500095922205575 1.1110327519207868 0.2665542518871648 1.0 0.5705271379133245 73 P35221,Q06481,Q8N0X7,Q9BQT9,P31749,Q96N67,Q13641,Q15375,Q13049,Q9Y4G8,Q9H2U1,Q13573,Q7L576,Q9UQB8,Q96G23,P07196,O94874 17 +Interleukin 6 production 0.4730256066691234 1.1071944024545366 0.2682098871383833 1.0 0.5725993200906915 16 Q9NRA0,Q7Z434,P05067 3 +Nucleoside triphosphate catabolic process 0.6176653948734301 1.1052122379798837 0.2690676352556558 1.0 0.5736485932059413 6 P00813 1 +Deoxyribonucleoside triphosphate catabolic process 0.6176653948734301 1.1052122379798837 0.2690676352556558 1.0 0.5736485932059413 6 P00813 1 +Regulation of monooxygenase activity 0.5258212212097642 1.1050114382105596 0.269154632878914 1.0 0.5736485932059413 10 Q8WTV0 1 +Response to ketone 0.3877859428088316 1.1037344884979816 0.2697083302728029 1.0 0.5741426851781745 41 P16278,O95831,O75116,P25705,Q13126,P07196,Q9NRA0 7 +Olfactory behavior 0.7004419635965566 1.1005079406730665 0.2711108717552437 1.0 0.5763152890078515 3 Q13641 1 +Chemosensory behavior 0.7004419635965566 1.1005079406730665 0.2711108717552437 1.0 0.5763152890078515 3 Q13641 1 +Mast cell activation 0.582044435875297 1.100053331871399 0.2713088856457819 1.0 0.5763152890078515 7 O95219,Q9NRA0,P51809 3 +Mast cell activation involved in immune response 0.582044435875297 1.100053331871399 0.2713088856457819 1.0 0.5763152890078515 7 O95219,Q9NRA0,P51809 3 +Negative regulation of protein localization to cell periphery 0.524833557537397 1.0999962056598491 0.2713337751067399 1.0 0.5763152890078515 10 Q9BXS4 1 +Negative regulation of protein localization to membrane 0.5191572743016823 1.0994349986075471 0.2715783719608811 1.0 0.5766496788959052 11 Q9BXS4 1 +Cellular response to dsrna 0.5441561768238014 1.098264871407324 0.2720888465242064 1.0 0.5772525966722851 9 Q5KU26,P41440,O75955 3 +Positive regulation of blood vessel endothelial cell migration 0.5125756156640772 1.0964699073407311 0.2728731855543231 1.0 0.5786613734399921 12 O00443,P09601,P25705,P78536,P09429,P31749 6 +Deoxyribonucleoside triphosphate metabolic process 0.5184655358776481 1.0958426716841518 0.2731476307701466 1.0 0.5788748930729919 11 P00813,Q9H773 2 +Neuronal action potential 0.6464758898344797 1.0929074980804554 0.2744344158301262 1.0 0.5806784733807974 5 Q06787,P04062,Q7Z406 3 +Regulation of oxidoreductase activity 0.4438544563738549 1.0920703413101942 0.2748021844486179 1.0 0.581001648286016 19 Q8WTV0,P06280 2 +Regulation of long chain fatty acid import into cell 0.6769419893303329 1.0917996656856723 0.274921166037811 1.0 0.581001648286016 4 P31751 1 +Negative regulation of interferon gamma production 0.6256522933260034 1.0917660515943317 0.2749359443262507 1.0 0.581001648286016 2 P09429 1 +Regulation of establishment or maintenance of cell polarity 0.5618607267475969 1.0910337717387255 0.2752580225752483 1.0 0.581313535473496 8 O75116,Q9NUQ9 2 +Regulation of lipase activity 0.5173304589598235 1.0899486510690344 0.2757357639799043 1.0 0.5821379579841895 11 P50897 1 +Demethylation 0.457431095816537 1.0892867469241412 0.2760274552751625 1.0 0.582507618660995 17 Q8NB78,Q16850 2 +Regulation of binding 0.343519677667317 1.089154621662886 0.2760857060980672 1.0 0.582507618660995 108 Q14012,Q9NVN8,Q71SY5,Q92797,O75503,P05067,P19474,Q08379,P16615,Q96D46,P48729,Q96TA1,Q13464,Q01664,Q9Y4G8,P30533,P41440,Q96HY6,Q9NWH9,O75955,P10586,O75844 22 +Regulation of cell killing 0.5169801246567755 1.0881296694837956 0.2765378674235048 1.0 0.5829078806209468 11 Q9NUQ9,P30511,P04439,Q9BY67 4 +Associative learning 0.4934609509456218 1.0877331627700777 0.2767129231287302 1.0 0.5830924120198385 14 Q13641,P05067,P50897 3 +Cellular response to oxygen containing compound 0.3443509054057129 1.087442406354123 0.2768413386044623 1.0 0.5831785770222992 230 Q9BSK2,Q99720,Q8WTV0,O94788,P14174,P39210,Q9UQB8,P05067,O95563,Q06481,O95831,O75116,O43865,Q96RR1,Q92542,Q14457,P43490,Q13464,Q01664,Q9Y4G8,Q13573,P09493,Q7L576,P11274,Q9NRA0,P08670,Q9NWH9,P25705,Q9NS86 29 +Regulation of leukocyte mediated cytotoxicity 0.5222252607394624 1.0867545657603088 0.2771452919459856 1.0 0.5833275220051829 10 Q9NUQ9,P30511,P04439,Q9BY67 4 +Response to ph 0.5608826424752962 1.0865015417890915 0.2772571591642034 1.0 0.5833275220051829 8 Q99538,O75592,P51798,Q9P2X3 4 +Nik nf kappab signaling 0.4430061131487447 1.086490066054231 0.2772622335570185 1.0 0.5833275220051829 19 P23396,O43657,P05067,O43707 4 +Negative regulation of telomere maintenance 0.5164057588711347 1.0851476693840674 0.277856257252083 1.0 0.5842083439793718 11 O60934,Q9NVN8,Q92878,Q9H0A0,Q00839,Q9NYB0,P07910,P18887 8 +Protein insertion into membrane 0.4066448889540366 1.0835177275612555 0.2785786865574542 1.0 0.5853578645639601 32 P46379,O43681 2 +Epigenetic maintenance of chromatin in transcription competent conformation 0.6439778503895079 1.0827055557243974 0.2789391372519163 1.0 0.5856794730730549 5 Q9NRA0 1 +Glycoprotein biosynthetic process 0.3507292546071264 1.0812062037198822 0.2796053990591622 1.0 0.5865902940589415 68 Q8NCH0,Q8WVQ1,O15118,Q08379,Q9HC07,Q96L58,O43505,O60476,Q9BXS4,Q9H9S5,O60502,O60512,P04843,P15291,Q9NQX7,Q92542,Q99805 17 +Negative regulation of fibroblast proliferation 0.5774181693555973 1.0794051837118843 0.2804071411137949 1.0 0.5875882099447837 7 Q71SY5 1 +Regulation of anatomical structure morphogenesis 0.3180936852913362 1.078973379553404 0.2805995948983064 1.0 0.5875882099447837 163 Q4VCS5,P84095,Q9UQB8,P35579,Q8N0X7,P02786,Q7Z406,O75116,Q15375,Q9H2J4,P00813,Q5VSL9,P55011,Q8N2A8,Q9NZM3,Q96TA1,Q13464,O43707,Q9Y4G8,P09493,Q7L576,P11274,Q14185,Q9NUQ9,P35580,Q9NZ08,P57105,Q9H2U1,O75844,P07196,Q9GZY8 31 +Nuclear pore complex assembly 0.5399425379078051 1.0778484003685294 0.2811014158791822 1.0 0.5878197419468423 9 P12270,P57740,Q8N1F7,Q9BTX1 4 +Dna methylation 0.4404049180534335 1.0759660232699153 0.2819424521361571 1.0 0.5885283704834633 20 Q96TA1,Q8NB78,O75844,Q8N2A8 4 +Regulation of chondrocyte differentiation 0.6421723909267877 1.0753359739742296 0.282224335724377 1.0 0.5887478863279662 5 Q92896 1 +Regulation of cartilage development 0.6421723909267877 1.0753359739742296 0.282224335724377 1.0 0.5887478863279662 5 Q92896 1 +Positive regulation of sister chromatid cohesion 0.6417788136818396 1.0737299077611515 0.282943752799129 1.0 0.5896947841415691 5 Q8IY18 1 +Positive regulation of cell cycle 0.347176328378166 1.0730378543352654 0.2832541321711614 1.0 0.58989319723464 95 Q96FV9,P06493,Q9Y6D9,P05067,Q8N7H5,P19474,Q8IY18,P12270,O75116,Q13769,Q96DY7,Q13049,Q14457,Q7LG56,Q9UJX3,P31350,P78536,P31749,Q99538,Q7L2J0,Q96HY6,Q9NYL9,Q9UPT9,P23246 24 +Positive regulation of mitotic cell cycle 0.3755863112740237 1.0728417033559663 0.2833421459542595 1.0 0.58989319723464 45 P11802,P06493,Q99538,Q7L2J0,Q7LG56,Q9UJX3,P31350,Q9NYL9,Q16513,P78536,Q96DY7,Q9UPT9,P05067,P31749 14 +Endodermal cell fate commitment 0.6415333175642832 1.0727281977874754 0.2833930848488792 1.0 0.58989319723464 5 Q8N7H5,Q92541,P35222 3 +Cell fate commitment involved in formation of primary germ layer 0.6415333175642832 1.0727281977874754 0.2833930848488792 1.0 0.58989319723464 5 Q8N7H5,Q92541,P35222 3 +Nucleotide salvage 0.5576173089148204 1.07137677011217 0.2840000535608888 1.0 0.5906031076392642 8 P00813 1 +Positive regulation of glycoprotein metabolic process 0.557480762104859 1.070744511707122 0.2842843226768474 1.0 0.5910098102951122 8 Q08379,P35610,Q9UHD1,Q92542,P35222 5 +Lymphocyte migration 0.5010938612468655 1.0691734445394523 0.2849915222776729 1.0 0.5915571691389826 13 P55011,P26038,P78536,P05067,P31749 5 +Adenylate cyclase modulating g protein coupled receptor signaling pathway 0.4408859997572777 1.0671863739829694 0.2858876843332774 1.0 0.5923102116643741 18 P07602 1 +Mitochondrial respiratory chain complex assembly 0.361562733753777 1.0666360631933862 0.2861362089906687 1.0 0.5924566688952224 51 P03886,Q9BSK2,O43676,Q69YU5,O95831,Q9Y2R0,Q96CU9,Q6DKK2 8 +Regulation of regulated secretory pathway 0.4314117501116 1.06619978404355 0.286333339766446 1.0 0.5924965971626801 25 Q4J6C6,P16615,P30511,O95219,P11274,Q9NRA0,O14936 7 +Sphingolipid mediated signaling pathway 0.6702390766693952 1.0653294178026318 0.2867268848567059 1.0 0.5931267413226425 4 P15311,Q9NRA0,P31749 3 +Leukocyte mediated cytotoxicity 0.4405693128051429 1.0651238723467162 0.2868198776455699 1.0 0.5931349611273844 18 Q9NUQ9,P51809,Q9BY67,P30511,P04439,P33176 6 +Regulation of protein tyrosine kinase activity 0.4657980969038345 1.0635841842307934 0.2875171102410132 1.0 0.5942775161150506 16 P78536,O95684,P05067 3 +Excitatory synapse assembly 0.6190606976105406 1.062650516969271 0.2879404688203442 1.0 0.5945920854694101 2 O15031 1 +Myeloid leukocyte activation 0.4276529908967111 1.0619808411750729 0.2882443829079093 1.0 0.5949728386974596 26 Q9NRA0,O95219,P05067,P14174 4 +Regulation of proteolysis 0.3233044177619579 1.0577669646219503 0.2901616972258356 1.0 0.5980041412359242 178 P46379,Q92896,Q12834,O00291,Q9Y366,P05067,P35579,Q9Y4X5,P19474,Q06481,Q15392,O95831,O75116,Q15375,Q9BXS4,Q6ZXV5,Q9H2J4,Q92542,Q13049,P23396,P48729,Q13464,Q01664,P61201,Q96F07,Q9BXK5,Q9H300,Q96HY6,Q96K76,Q9Y5X1,Q96A26,Q93009,Q96KC8,Q9NWW5,O60826 35 +Specification of symmetry 0.5161387866023172 1.0558755559590824 0.2910250731789781 1.0 0.5990741027794687 10 O94788 1 +Definitive hemopoiesis 0.6887362637362646 1.0548917938014148 0.2914748157971396 1.0 0.5990741027794687 3 P11274,P55265 2 +Protein autoubiquitination 0.476228001323463 1.054756677774193 0.2915366227233913 1.0 0.5990741027794687 15 P19474 1 +Bile acid biosynthetic process 0.5351641120681556 1.054714043205669 0.2915561271354412 1.0 0.5990741027794687 9 Q9H4L5 1 +3 utr mediated mrna stabilization 0.5714821458860003 1.0529405621298975 0.2923682342723965 1.0 0.600138491976888 7 Q16539,P98175,Q13151 3 +Monocyte differentiation 0.5711970810513167 1.0516705910722046 0.292950708261924 1.0 0.6011407268596415 7 P35579,O00625 2 +Dicarboxylic acid transport 0.4384633432620395 1.0514103078345516 0.2930701836512264 1.0 0.6011407268596415 18 P55011,Q9H2D1,Q9UBX3,Q9BQT8,P80404,Q15758,P41440 7 +Cell morphogenesis 0.3292005031594605 1.0483636047613356 0.2944711152216264 1.0 0.6022286803933998 194 P07942,P84095,Q96N67,Q9UQB8,P05067,P35579,Q06481,Q8N0X7,Q7Z406,Q15375,P42892,O75592,Q5VSL9,P33176,P12814,Q9NZM3,Q96TA1,Q13464,O43707,Q13641,Q9Y4G8,Q96F07,P09493,Q7L576,P41440,Q14185,P35580,Q9NWH9,O75955,O75844,P07196 31 +Regulation of nik nf kappab signaling 0.4861578152977364 1.0466597253516503 0.2952565451527582 1.0 0.6032794726626275 14 P23396,P05067,O43707 3 +Cellular response to acid chemical 0.4966732708574793 1.0451201917103723 0.2959674229731805 1.0 0.603991099317091 13 P17655,Q9UQB8 2 +Megakaryocyte development 0.6648531793339456 1.0440981701671868 0.2964399723916668 1.0 0.6046968524148342 4 Q9Y6W5,Q8IZP0 2 +Protein localization to vacuole 0.4143765726752963 1.0437836039439137 0.2965855190892508 1.0 0.6046968524148342 29 Q99523,Q9NUN5,Q14108,P20645 4 +Negative regulation of b cell proliferation 0.6146663004668986 1.0432847211878262 0.2968164452443362 1.0 0.6049825557243843 2 Q96IZ0 1 +Establishment of lymphocyte polarity 0.6642887191123612 1.0418752058426834 0.2974695407411751 1.0 0.6059356253233654 4 P35579 1 +Skeletal muscle cell differentiation 0.5324131183540578 1.041405992466231 0.2976871625435431 1.0 0.6059356253233654 9 P50402,Q9BRT2,P61201 3 +Regulation of dendrite morphogenesis 0.4619909407771041 1.040627822051291 0.2980483135211422 1.0 0.6061953336359496 16 Q9UQB8 1 +Positive regulation of innate immune response 0.4052284604463018 1.0371007150983873 0.2996889219709429 1.0 0.6084178205644096 31 P26583,Q9NZI8,Q15233,Q9BY67,Q7Z434,P30511,Q8WXF1,P12956,Q15648,Q9BUI4,P43243,P13010,Q9NUD5,P09429,P11279,P23246 16 +Negative regulation of proteolysis involved in cellular protein catabolic process 0.4134321583030245 1.0367273233693444 0.2998629543531641 1.0 0.6085857035806069 29 P46379,Q9H2J4,Q96HY6 3 +Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.6827496332579307 1.031632107178254 0.3022444934990289 1.0 0.6119993899431277 3 A2RRP1 1 +Skin development 0.3754765639999697 1.0308576629325237 0.3026075728152175 1.0 0.6122909983807454 43 P22466,Q16739,Q13464,Q15392,O75116,O75844,P11274 7 +Astrocyte development 0.5997736734556578 1.0293968957719306 0.3032932072392613 1.0 0.6133058087511983 6 P05067 1 +Positive regulation of mitotic cell cycle phase transition 0.3888822336111558 1.028742531593364 0.3036006781412328 1.0 0.6134157384111547 35 P11802,P06493,Q7L2J0,Q7LG56,Q9UJX3,P31350,Q9NYL9,P78536,Q96DY7,P05067,P31749 11 +Adherens junction maintenance 0.6818681318681328 1.0282116972637518 0.303850257275466 1.0 0.6135012921898272 3 Q96AC1,Q07157 2 +Cell cell junction maintenance 0.6818681318681328 1.0282116972637518 0.303850257275466 1.0 0.6135012921898272 3 Q96AC1,Q07157 2 +Neurotrophin trk receptor signaling pathway 0.5990757371612001 1.026446846754147 0.3046810058627107 1.0 0.6146199037430341 6 Q99523,Q96F07 2 +L aspartate transmembrane transport 0.6807022914061984 1.023689836079039 0.3059817976096424 1.0 0.6161762156308966 3 Q15758 1 +Wound healing 0.3429479494946176 1.021761218247665 0.3068939287539487 1.0 0.6175881145537784 70 P35579,P12814,P42785,P55011,Q9HD42,Q8WTV0,P80404,P15291,P09493,P78536,O14936 11 +Positive regulation of receptor clustering 0.6094479538588238 1.020339276222921 0.3075675821211008 1.0 0.6185701176193464 2 Q15334 1 +Phospholipid transport 0.4308897463368336 1.020027620359291 0.3077153615905637 1.0 0.6186805836686559 21 Q14108,P61916,Q8WTV0,Q9H1P3,O14523 5 +Immunoglobulin production 0.421712875056983 1.0197151791207248 0.3078635606292763 1.0 0.6187015226024126 26 Q9UQ84,P20585,P02786,Q9NQT5,O96028 5 +Cell matrix adhesion 0.3762792732026139 1.0195996934618867 0.3079183504465237 1.0 0.6187015226024126 42 P12814,P46939,Q13464,Q13136,O75116,Q9UM22,P11274,O14936 8 +Negative regulation of transforming growth factor beta receptor signaling pathway 0.4980651313629697 1.01941846214007 0.3080043449605587 1.0 0.6187015226024126 12 Q92896 1 +Pyroptosis 0.6083493545729133 1.0155162593488074 0.3098597999931782 1.0 0.6217680123433572 2 Q9NZI8 1 +Spindle elongation 0.5628885773981249 1.0146997318414142 0.3102489820039018 1.0 0.6222724163431662 7 O95239,O43663 2 +Deoxyribonucleoside monophosphate metabolic process 0.5266706093884606 1.013656050185733 0.3107469023147162 1.0 0.6225215304037747 9 P00813 1 +Regulation of cell morphogenesis 0.3415258829080634 1.013422101977112 0.3108585867863849 1.0 0.6225580894973497 73 P35579,P35580,Q9NZM3,P84095,O75844,Q7Z406,O43707,Q9H2U1,P09493,Q7L576,Q9UQB8,Q5VSL9,Q14185 13 +Cellular defense response 0.6567287764974687 1.0121453905131177 0.3114685423286358 1.0 0.6235922168076024 4 Q14457 1 +Postsynapse to nucleus signaling pathway 0.6064268058225697 1.007082665090966 0.3138950508088591 1.0 0.6273912751288309 2 P52292 1 +Positive regulation of protein localization to early endosome 0.655179414075526 1.006062920755901 0.3143853037562931 1.0 0.6275462189718937 4 O75116,P26038 2 +Regulation of protein localization to endosome 0.655179414075526 1.006062920755901 0.3143853037562931 1.0 0.6275462189718937 4 O75116,P26038 2 +Glial cell development 0.427504845796715 1.0056396057111634 0.3145889647781128 1.0 0.6276058597527435 22 P08670,P05067,Q92542,Q8N3R9 4 +Neuron projection maintenance 0.6760292261690102 1.0055866608534507 0.3146144431698956 1.0 0.6276058597527435 3 P05067 1 +B cell differentiation 0.4440024844811041 1.005240106897803 0.3147812471137463 1.0 0.6276058597527435 17 P00813 1 +Connective tissue development 0.4091650176541637 1.0048638408862525 0.3149624179228694 1.0 0.6276058597527435 29 O15173,Q92896,P43490,Q8N0X7,Q9NX62,Q96HY6,O75844 7 +Regulation of mitochondrion organization 0.3552894475442021 1.0046732628742483 0.3150542067286237 1.0 0.6276058597527435 51 Q5THJ4,P21796,O60313,Q8N2A8,Q9H3K2,P27544,Q9NUQ9,P02786,Q96A26,P02545,Q9H300,Q9Y6C9,P31749,Q9GZY8 14 +Golgi to lysosome transport 0.593807365315559 1.0042003150293446 0.3152820703125722 1.0 0.6276439899888464 6 Q99523 1 +Regulation of dendrite extension 0.6755494505494517 1.0037300949621295 0.315508726980001 1.0 0.627733740659483 3 Q9NZM3,Q9Y263 2 +Regulation of mast cell activation 0.5933835098513827 1.0024122854078543 0.3161445110226757 1.0 0.6284220993269953 6 O95219,Q9NRA0,P51809 3 +Regulation of mast cell activation involved in immune response 0.5933835098513827 1.0024122854078543 0.3161445110226757 1.0 0.6284220993269953 6 O95219,Q9NRA0,P51809 3 +B cell lineage commitment 0.6047789068937042 0.999860830606358 0.317377862387453 1.0 0.6295590047894014 2 P04637 1 +Immunoglobulin v d j recombination 0.6047789068937042 0.999860830606358 0.317377862387453 1.0 0.6295590047894014 2 P25490 1 +Histone h3 deacetylation 0.6232386684418671 0.9982894782558572 0.3181390082124662 1.0 0.6301308596075096 5 P23246 1 +Protein containing complex localization 0.3626166495989512 0.9972826667243652 0.3186273247513091 1.0 0.6307230733267895 47 P33176,Q9BTX1,Q96EE3,A0AVF1,O15400,Q14168,P57105,O00291,Q9Y366,O43805,Q9UPN4,Q96GA3,P23246,Q96D46 14 +Mitotic recombination 0.5225253394865453 0.9936533570212894 0.3203916579480907 1.0 0.6330279650217906 9 Q8IY18,P20585 2 +Cop9 signalosome assembly 0.6729090247209437 0.9935197099304146 0.3204567501153383 1.0 0.6330279650217906 3 Q9H9Q2 1 +Learning 0.4284546876541795 0.9908752967309118 0.3217464762382023 1.0 0.634447106000338 19 P05067 1 +Protein localization to plasma membrane 0.3413032467957358 0.9891017801524826 0.3226133467500396 1.0 0.6358097047642527 85 Q9BZG1,Q4J6C6,P84095,Q8IWJ2,Q13464,Q13136,O75116,Q9Y4G8,Q9BXS4,Q13641,Q01082,Q8N3R9,O75955,P31751,O14976,P41440,P33176 17 +Regulation of vesicle mediated transport 0.3086209987276556 0.9889080724687886 0.3227081205986652 1.0 0.6358097047642527 140 P26038,Q4J6C6,Q8WTV0,P30511,O00291,P05067,Q06481,P16615,Q07960,O14936,P50897,Q13464,P30533,P41440,P11274,Q9H223,Q9NRA0,Q969M3,P51809,Q93009,P57105,P31751,O95219,O75955 24 +Regulation of t cell migration 0.5901725710105666 0.9888761081119862 0.322723761295618 1.0 0.6358097047642527 6 P05067 1 +Endomembrane system organization 0.3288685270904885 0.9874715084197184 0.3234115437118154 1.0 0.6367867516978354 203 Q92538,Q86XL3,P46379,Q14108,Q9HD42,Q7RTS9,Q15629,P02545,O14976,Q8N3R9,Q9UQB8,P35579,Q8N4V1,Q9UH99,Q08379,P16615,Q14203,Q96ED9,Q96CP7,P20700,P48729,Q16739,Q8IWJ2,P51790,Q5VU43,O43752,Q8N1F7,P41440,Q969M3,Q15075,Q9Y5X1,O15260,Q01082,P31751,O43681,O75955,Q8TBA6,O75844 38 +Fertilization 0.4102822536858331 0.9858248022968076 0.3242190926320787 1.0 0.6373398382428591 28 P35579,P78371,Q96CW5,P45880,P15291,P55769 6 +Response to toxic substance 0.3531310305262321 0.98539277556606 0.3244311769173686 1.0 0.6373398382428591 52 P00390,Q15165,O95831,P07099 4 +Response to potassium ion 0.6497441661151526 0.9847560333597576 0.3247439217821561 1.0 0.6373398382428591 4 Q14168 1 +Cellular response to potassium ion 0.6497441661151526 0.9847560333597576 0.3247439217821561 1.0 0.6373398382428591 4 Q14168 1 +Negative regulation of lymphocyte activation 0.4279366013079747 0.9829415130727726 0.3256362248577829 1.0 0.6385268293782835 18 Q8WXW3,Q9Y6D9,P30511,P22466 4 +Response to epidermal growth factor 0.4278120232557959 0.9821322628988596 0.3260346929343365 1.0 0.6389321055945543 18 P12270,Q9Y448,Q9UQB8,Q14457,P31749 5 +Regulation of rho protein signal transduction 0.4739483715676928 0.9781268413465208 0.3280115939659951 1.0 0.6420508961796197 14 P41440,P11274,O75955 3 +Ubiquitin dependent erad pathway 0.3734426845993002 0.9775148361706224 0.3283143364602221 1.0 0.6424547500248047 41 O60858,Q8IXB1,P46379 3 +Response to testosterone 0.5187632542144887 0.9755237325955314 0.3293005353101823 1.0 0.643817331799221 9 O75116,P49321,Q13126 3 +Negative regulation of nuclear division 0.423890293621451 0.9731630063980108 0.3304722935821207 1.0 0.6455399859682411 21 O60566,Q96DY7,P12270,Q96EA4,Q6ZVM7,Q9Y6D9 6 +Positive regulation of muscle contraction 0.5533617215700855 0.97243059840582 0.330836375744084 1.0 0.6456832957184626 7 P00813 1 +Regulation of lymphocyte migration 0.517999676069945 0.9718470549025168 0.3311266426027552 1.0 0.646060562126547 9 P78536,P05067,P26038 3 +Cellular response to peptide 0.3390468457001003 0.9710662136677592 0.331515307099171 1.0 0.6465392326410916 78 Q9BSK2,Q06481,P43490,P08670,Q13464,O75116,O43865,Q7L576,Q9UQB8,P05067 10 +Negative regulation of mononuclear cell migration 0.6670329670329681 0.9708428912126382 0.3316265202891721 1.0 0.6465392326410916 3 O94813,P31749 2 +Postsynapse organization 0.3829927375490696 0.9703621263034314 0.3318660200523837 1.0 0.6467456249222091 34 P12814,P49354,Q16352,Q15375,Q9H2U1,Q99538,Q9UQB8,P07196 8 +Membrane biogenesis 0.4044741281591956 0.9698807000214016 0.3321059612749806 1.0 0.6470239824488877 29 Q9HD42,Q16739,Q01082,O14976,O75955,P41440,Q96CP7 7 +Metal ion transport 0.3269297459967613 0.9692833071258556 0.3324038556653796 1.0 0.6473111927571008 120 Q9HC07,P14373,O75027,P46939,P21796,Q8N4V1,P22466,Q9NWR8,P02786,P16615,Q07960,Q6P4Q7,Q9HD20,O43865,Q9BPX6,P33176,O14936,P55011,O15173,O43707,Q9NRA0,Q9Y6M7,Q13555,Q9H4I9,O75844,Q8IYU8 26 +Vasculogenesis 0.5168261368562792 0.9661984900328704 0.3339448683153625 1.0 0.6495691298118752 9 Q4VCS5,Q96PU8,Q92990,Q9Y4G8,O95470,P35222 6 +Negative regulation of dna replication 0.5161183309598911 0.962792887366334 0.335651470838207 1.0 0.6518349607096978 9 Q29RF7 1 +Sterol homeostasis 0.4807430627965037 0.9586452418170144 0.3377374927637833 1.0 0.654148287256192 13 Q8WTV0,O15118 2 +Peripheral nervous system development 0.480687808524288 0.95834603677555 0.3378882967362056 1.0 0.654148287256192 13 Q9NR77,Q8N3R9 2 +Vesicle mediated transport in synapse 0.3746103597667511 0.9575630617054685 0.338283132954843 1.0 0.654148287256192 39 Q9NZM3,Q4J6C6,P16615,Q13464,Q7L0J3,O14976,Q7L576,O14936 8 +Notch signaling pathway 0.4202205752872613 0.9563855455783284 0.338877484668969 1.0 0.6544961825127101 22 P78536,P57105,Q92542,P05067 4 +Erk1 and erk2 cascade 0.3710334968037379 0.9563644021566636 0.3388881629399445 1.0 0.6544961825127101 41 Q86VI3,P14174,Q9Y4G8,P57105,P05067 5 +Establishment or maintenance of cell polarity 0.3369471348054791 0.9543880560786522 0.3398872498453267 1.0 0.6560454072188331 75 Q92538,Q4VCS5,P26038,P84095,Q96N67,P02545,Q8N3R9,Q9Y5S2,P35579,P35221,Q14203,Q96L92,O75116,Q13464,Q14168,Q96EA4,Q9BX67,Q9NUQ9,P57105 19 +Neurogenesis 0.3543627643714155 0.9539328671020324 0.3401176252607658 1.0 0.6562711986457663 302 Q14012,P07942,Q14108,O94788,P84095,Q96N67,O14976,Q8N3R9,P54802,Q12834,O75503,Q9NY93,Q9UQB8,Q96G23,P05067,Q9NR77,Q06481,Q8N0X7,Q8WUJ1,Q15375,Q8NHS3,P42892,O75592,Q969N2,Q13049,Q14457,Q92542,P33176,Q9NZM3,O15078,P50897,Q96TA1,Q9P2X3,Q16739,Q13464,P61201,Q13641,Q9Y4G8,Q96F07,Q13573,Q7L576,P41440,Q9Y6M7,Q96N66,Q15555,Q96RK4,P08670,Q13555,Q9NWH9,O75306,Q8NAT1,P31751,Q9BSJ2,O75955,P10586,Q9NQX7,P07196 57 +Rna interference 0.4905872472565044 0.9514848688830466 0.3413582960195058 1.0 0.6573613660051929 11 O75569,Q9H7Z3,P55265,Q5KU26 4 +Kinetochore organization 0.5314985920430875 0.9508823362032582 0.3416641095159052 1.0 0.657531010919537 8 Q9BS16 1 +Transforming growth factor beta production 0.6410359840073078 0.9507280562927004 0.3417424419652344 1.0 0.657531010919537 4 O75787,P06756 2 +Protein acylation 0.341074014902143 0.9500013531053104 0.3421115650800885 1.0 0.6580512003835537 66 P46379,Q8IY18,Q9UPT9,Q9NRA0,Q6N069 5 +Deoxyribose phosphate catabolic process 0.5132476111508135 0.9489905785004564 0.3426254038813352 1.0 0.6582794308135341 9 P00813 1 +Positive regulation of supramolecular fiber organization 0.349578862378867 0.9483669192255544 0.3429426941874292 1.0 0.6584897028523768 51 P23396,Q9Y5X1,Q9NWH9,Q14203,O75116,P14373,P09493,Q7L576,Q9UQB8,P05067,Q16625 11 +Regulation of innate immune response 0.3492647905603581 0.9470505395393792 0.3436130263186057 1.0 0.6592264884425193 52 P19474,Q06481,Q9BY67,Q9NZ08,P30511,P12956,P23246 7 +Positive regulation of type i interferon production 0.4216471898743764 0.94625943593982 0.3440162775391733 1.0 0.659381521951346 19 Q9NUD5,O14802,Q13283,Q7Z434,P42224,Q9H2U1,Q9BUI4,O75955,O15111,P41440,P26583 11 +Cilium or flagellum dependent cell motility 0.5304649092220015 0.946137255383558 0.3440785838621247 1.0 0.659381521951346 8 Q9UPN4,Q00796 2 +Positive regulation of neuron projection arborization 0.592419664927211 0.945921466219917 0.344188643756083 1.0 0.659381521951346 2 Q15334 1 +Neural plate morphogenesis 0.592419664927211 0.945921466219917 0.344188643756083 1.0 0.659381521951346 2 Q9HCM4 1 +Digestion 0.4573387013202829 0.9450966746327532 0.3446095228800641 1.0 0.659808405445364 15 Q8WTV0,Q16739 2 +Type i interferon production 0.411139354212882 0.9446447335735012 0.3448402810073994 1.0 0.6600061913456491 26 Q7Z434,P19474,P41440,O75955 4 +Retina morphogenesis in camera type eye 0.5794502497426748 0.9438041202647892 0.345269754711373 1.0 0.6604748497038866 6 Q15555,P54802 2 +Chondrocyte differentiation 0.4890652658199975 0.94363910633333 0.3453541012109171 1.0 0.6604748497038866 11 Q92896 1 +Amino acid import 0.4938616259995616 0.9432532648335038 0.3455513744872629 1.0 0.6605170319655554 10 P30825 1 +Negative regulation of protein maturation 0.6089453592412053 0.9404960599974044 0.346963169703796 1.0 0.6626012037077652 5 Q9BXS4 1 +Fibroblast migration 0.433581255653883 0.94019885560615 0.34711556870118 1.0 0.6626519124253469 17 P46940,Q5SNT2,Q06481,O95470,P31749 5 +Positive regulation of mononuclear cell migration 0.4830182311853228 0.9398163222716795 0.3473117849402065 1.0 0.66269714291426 12 P05067 1 +Regulation of response to biotic stimulus 0.3347156738250324 0.9388160019266534 0.3478252216601598 1.0 0.663046350791884 72 P19474,Q06481,Q9NZ08,P30511,P14174,P12956,O75844 7 +Alcohol metabolic process 0.3360901530731285 0.938049481432345 0.3482189818522896 1.0 0.663046350791884 96 Q16850,P30837,Q9NX62,Q8WTV0,O94788,O15118,P61916,Q96PE3,Q15392,P49748,Q9NWW5,Q9NRA0,Q9UBM7,P48735,P05067,Q00796 16 +Negative regulation of transforming growth factor beta production 0.5904971161768676 0.9375697095667436 0.3484655839108379 1.0 0.663046350791884 2 Q9Y5K6 1 +Transforming growth factor beta activation 0.5904971161768676 0.9375697095667436 0.3484655839108379 1.0 0.663046350791884 2 P06756 1 +Regulation of transforming growth factor beta activation 0.5904971161768676 0.9375697095667436 0.3484655839108379 1.0 0.663046350791884 2 P06756 1 +Negative regulation of transmembrane transport 0.417344320514117 0.9369714407258218 0.3487732486865527 1.0 0.6633959908645448 22 P21796 1 +Mannosylation 0.5278041473377244 0.9339336013899656 0.3503381447484697 1.0 0.6656987055630659 8 Q6ZXV5,Q9H9S5,O43505 3 +Neural retina development 0.5100297457290324 0.9335396910914864 0.3505413872385974 1.0 0.6658087979392174 9 Q15555,P20020,O75147,P54802,Q96RK4 5 +Negative regulation of telomere capping 0.6568681318681329 0.9317784216080528 0.3514510485075228 1.0 0.6665949358968819 3 Q92878,P18887 2 +Regulation of protein serine threonine kinase activity 0.3436281380966804 0.931576280041624 0.3515555462616904 1.0 0.6665949358968819 61 P23396,Q14012,P54619,Q01664,P14174,Q9Y4G8,P78536,Q8NDZ4 8 +Glycoside metabolic process 0.5089085012829999 0.9281613245899496 0.3533238929485933 1.0 0.6690671510341286 9 Q9BTY2,P04066,P06280 3 +Import across plasma membrane 0.4132633423628063 0.9279045370396825 0.3534570907400094 1.0 0.6690671510341286 24 P11166,P55011,Q01650,P31751,Q15758,P30825,P41440,Q9Y666,P31749 9 +Mucopolysaccharide metabolic process 0.4805713751613395 0.926913696639503 0.3539713452398176 1.0 0.6696510713608476 12 P16278,Q8NCH0,Q9NX62,Q96L58,O43505 5 +Sulfur amino acid metabolic process 0.4805244051079936 0.9266661530981596 0.3540998961939219 1.0 0.6697041181777184 12 Q13126 1 +Regulation of keratinocyte differentiation 0.5083521620845198 0.925493762123039 0.3547091269503195 1.0 0.6702757471276353 9 O75116 1 +Positive regulation of phagocytosis 0.485390887454348 0.9247188872338182 0.3551121522630929 1.0 0.6702757471276353 11 Q06481 1 +Acute inflammatory response 0.5748870120664086 0.9246906045174316 0.3551268680389152 1.0 0.6702757471276353 6 P42785 1 +Sterol metabolic process 0.3593648785849974 0.9235807813665206 0.3557046237929491 1.0 0.6710248891088392 45 Q16850,P49748,O15118,Q8WTV0,P61916,Q15392,Q9NWW5,Q9UBM7,P05067 9 +Protein localization to phagophore assembly site 0.6041886187214952 0.9213517664082184 0.3568668024176822 1.0 0.6724557422254006 5 Q5MNZ6,P50851,O95140 3 +Negative regulation of leukocyte degranulation 0.6334052537899936 0.9210348252629852 0.3570322453304726 1.0 0.672577283188278 4 P11274,P30511 2 +Cellular response to organic cyclic compound 0.3202116723610143 0.91927253253707 0.3579530410019533 1.0 0.6731384960620111 124 P26038,O15118,Q5KU26,Q9P1Z2,P05067,P35221,Q7Z434,P53985,O95831,O75116,Q92542,O94874,Q9P2X3,O15173,Q01664,Q9Y4G8,Q13573,P41440,P25705,O75955,Q96HY6,Q9NUQ7 22 +Regulation of reactive oxygen species metabolic process 0.3729614668572742 0.9182189186957688 0.3585042660015172 1.0 0.6731384960620111 37 Q9BSK2,P42785,P51790,P39210,O75027,Q9NRA0,P11274,Q14457 8 +Foam cell differentiation 0.6532967032967045 0.9181072198913224 0.3585627353663576 1.0 0.6731384960620111 3 P42224,P06756 2 +Positive regulation of neuron projection development 0.3933940585263455 0.9152034595170452 0.3600848288256628 1.0 0.6747534825736327 30 Q14012,Q14108,Q7L576,Q9Y4G8,Q9NY93,Q9UQB8 6 +Apoptotic signaling pathway 0.3050337243454149 0.912661678210308 0.3614205046108356 1.0 0.676394067094309 157 P46379,Q07820,P14174,P02545,O00291,O60313,P35221,P09601,O95831,Q15118,P32929,Q13049,Q14457,P23396,Q96RU2,Q9NYF8,O95155,Q9H3K2,Q15233,Q8N2F6,Q8WUK0,Q7LG56,P45880,Q13573,O95470,Q8IXB1,Q9H300,P31749,Q96K76,O75569,Q96A26,Q99523,Q9NQX7,P26583,P23246,Q9GZY8 36 +Response to hormone 0.3211893715443192 0.9125122845462362 0.3614991057356973 1.0 0.676394067094309 195 Q9BSK2,P42785,O15118,Q9P1Z2,Q9UQB8,Q00796,P16278,P11166,P22466,Q06481,Q15392,O95831,O75116,O43865,O75592,O15173,P43490,Q16739,Q13464,Q01664,Q7L576,Q99523,P25705,P31751,Q9NS86,P07196 26 +Regulation of ion transport 0.3347507177767038 0.9124727633248346 0.3615199009966625 1.0 0.676394067094309 91 P21796,P33176,P22466,Q13555,O14936,P80404,P14174,O43707,Q7L0J3,P14373,O95219,O43865,Q9NRA0,O75844,P05067,P46939 16 +Cellular response to gamma radiation 0.4876738076815143 0.9121348344199548 0.3616977429171579 1.0 0.676394067094309 10 P12956 1 +Circadian regulation of gene expression 0.4169076892499453 0.9114347484644864 0.3620663517514093 1.0 0.676703534844219 18 P43490,Q9Y2K7 2 +Regulation of natural killer cell activation 0.6308054607731577 0.9109475929303186 0.3623229874117464 1.0 0.6768665452301985 4 P30511 1 +Regulation of receptor mediated endocytosis 0.3928224083847467 0.9108835362339696 0.3623567412330959 1.0 0.6768665452301985 30 P50897,P30533,O00291,O75955,P41440,P05067 6 +Response to angiotensin 0.6014361930101569 0.9102971041778964 0.3626658453271845 1.0 0.6770643114079659 5 O75116,O43865 2 +Regulation of cell adhesion 0.3291779190886802 0.9074588013782212 0.3641642264745632 1.0 0.6791005432409782 109 P23396,Q9NUQ9,Q9HCL2,P02786,O14936,Q13464,P80404,Q9BX67,O43707,O75116,Q15375,P30825,P09493,P00813,O75955,P41440,Q14185,P46939 18 +Intermediate filament organization 0.5385810083698856 0.9071893727197202 0.3643066626182309 1.0 0.67917607527288 7 P08670,P07196 2 +Cell substrate adhesion 0.3389674991185448 0.90696289049509 0.3644264216381179 1.0 0.6792092999649733 64 P07942,P12814,O14936,Q13464,Q13136,O75116,O43707,Q9UM22,P11274,Q14185,P46939 11 +Regulation of muscle adaptation 0.4156063164984355 0.9030188162523264 0.3665159086113525 1.0 0.6822682316890546 18 Q13555,P16615,P02545,O75116,Q14457 5 +Defense response to symbiont 0.3335787430997581 0.9025321352421044 0.3667742587430205 1.0 0.6822682316890546 69 P19474,Q9HCL2,Q7Z434,Q9HCE1,O75844,O60858,P14373,Q9H2U1,Q9NY93,O43657,Q13049,Q14457 12 +Hyperosmotic response 0.5033992392430995 0.9017783680577762 0.3671746131371332 1.0 0.6825200089888932 9 Q9BPX6,P11166 2 +Regulation of neurogenesis 0.3365940819669603 0.9010097898797608 0.3675831145143962 1.0 0.6826895721083459 66 P35221,Q06481,Q8N0X7,Q96N67,Q15375,Q13049,Q9Y4G8,Q9H2U1,Q13573,Q7L576,Q9UQB8,Q96G23,P07196 13 +Protein homotetramerization 0.4130596461009062 0.900871504075243 0.3676566438325581 1.0 0.6826895721083459 21 O94788,Q06481 2 +Pattern specification process 0.3628830830705252 0.9007369802071236 0.3677281816444324 1.0 0.6826895721083459 42 Q8N2A8,O15344,O75569,O94788,O75787,Q9Y366,Q9Y2W6,P29372 8 +Positive regulation of wound healing spreading of epidermal cells 0.6483516483516495 0.8992285730580329 0.3685309238595167 1.0 0.683798815281526 3 Q96AC1,P42345 2 +Regulation of muscle organ development 0.5681588941879809 0.8965945296087614 0.3699353181685534 1.0 0.6854502294096416 6 P41440,O75955 2 +Mitochondrion morphogenesis 0.4797344490727896 0.8956568966729861 0.3704360379064768 1.0 0.6861871894831402 11 Q9GZY8 1 +Platelet derived growth factor receptor signaling pathway 0.4842633276920608 0.8950241468299674 0.3707741800907072 1.0 0.6862412116512171 10 P46940,O00291,O95470 3 +Positive regulation of reproductive process 0.597400041797836 0.894118905006316 0.3712582753235842 1.0 0.6868963843474738 5 O14965,Q8IY37,P35222 3 +Central nervous system neuron development 0.4582366874892218 0.8903506986848653 0.3732776061194229 1.0 0.6882307397664583 14 Q9Y4G8,Q8N3R9 2 +Regulation of cell projection organization 0.3128763856217392 0.8900543544001003 0.3734367009240569 1.0 0.6882307397664583 130 Q14012,Q14108,P51114,P84095,Q96C92,O14976,Q12834,Q9NY93,Q9UQB8,Q96G23,Q16625,Q9NR77,Q8N0X7,Q15375,Q9Y4G8,Q7L576,Q15555,Q96RK4,P08670,Q13555,Q8NCA5,Q9H2U1,P10586,Q9NQX7,P07196 25 +Gland development 0.3322154634415098 0.889211101385415 0.3738896376758283 1.0 0.6883743177214822 79 P11717,P07602,Q9BY67,O94788,Q9UNS2,Q86VI3,O75844,Q9NWH9,Q13505,P00813,O75592 11 +Positive regulation of cilium assembly 0.517750861992994 0.8879744745965653 0.3745544818460578 1.0 0.6890525206136189 8 Q96C92,Q15555 2 +Negative regulation of catabolic process 0.3281464402553409 0.8877566578044935 0.3746716617414289 1.0 0.6890525206136189 108 P46379,O60506,P98175,O15118,Q07820,P35637,Q92804,Q9H7Z3,Q9Y2W1,A2RRP1,Q08379,P09601,Q9H2J4,O75592,P10619,Q14457,Q16850,Q13464,P31749,Q13151,Q9H814,Q9NWH9,Q93009,Q96HY6,Q9NZM5,Q9H2U1 26 +Mitochondrial electron transport cytochrome c to oxygen 0.5173806489342987 0.886286997638022 0.3754628937541939 1.0 0.6897461431166789 8 Q7KZN9,P00403 2 +Purine containing compound transmembrane transport 0.4777346296834586 0.8854026558259468 0.3759395005221035 1.0 0.690241083488227 11 Q86VD7,P41440 2 +Amp biosynthetic process 0.4772490357924985 0.882914463316806 0.3772824884905144 1.0 0.691183178667115 11 P00813 1 +Protein autoprocessing 0.6232266264247692 0.8816342255222515 0.3779746405976527 1.0 0.6922608659434195 4 P17655 1 +Signal transduction in response to dna damage 0.3501062516234743 0.8795921774641015 0.3790802780596647 1.0 0.6934324436750113 47 Q9UNS2,O75844,P14174 3 +Protein localization to early endosome 0.5639038065495874 0.8788829999534881 0.3794647170627052 1.0 0.6938456119069168 6 O75116 1 +Cell aging 0.384478299824282 0.877079717468741 0.3804433404418432 1.0 0.6939211544932936 31 Q8IY18,O75844,P14174 3 +Positive regulation of nervous system development 0.3497404376214996 0.8761630307867823 0.3809414110543114 1.0 0.6944962223809509 47 Q9BQT9,Q13641,Q13573,Q9UQB8,Q13049,P07196 6 +Endochondral bone morphogenesis 0.5619528097098605 0.8707780676247743 0.3838753428419172 1.0 0.697513103517834 6 Q9NX62 1 +Regulation of t cell receptor signaling pathway 0.5618186307177631 0.8702210360730367 0.3841796220700759 1.0 0.697513103517834 6 P00813 1 +Multicellular organism growth 0.3672312831837707 0.8701978892704785 0.3841922692346466 1.0 0.697513103517834 37 Q9HCL2 1 +Tumor necrosis factor mediated signaling pathway 0.4333960798766138 0.8690088637723782 0.3848422826217508 1.0 0.6984051985765181 16 P78536,Q13049,Q8TCT8 3 +Interferon gamma mediated signaling pathway 0.5909840571742598 0.8684862981482564 0.3851281700246687 1.0 0.6984051985765181 5 P42224,Q15648,Q16543,P04637 4 +Natural killer cell activation involved in immune response 0.619800283792779 0.8684301096904548 0.385158917570477 1.0 0.6984051985765181 4 P30511 1 +Natural killer cell degranulation 0.619800283792779 0.8684301096904548 0.385158917570477 1.0 0.6984051985765181 4 P30511 1 +Protein localization to endoplasmic reticulum 0.3626351998516813 0.8683409149249599 0.3852077299667873 1.0 0.6984051985765181 40 Q92538,P46379,Q15629,Q99442,O43681,Q96HY6 6 +Regulation of synaptic transmission dopaminergic 0.6398665192877462 0.866983159236527 0.3859512370625495 1.0 0.6989794739829781 3 P41440 1 +Oocyte differentiation 0.4786163397720209 0.8667643326749517 0.3860711484534573 1.0 0.6989794739829781 10 Q9Y2W6,Q8N2A8,Q5TAX3,P35222 4 +Carbohydrate homeostasis 0.3409438702845224 0.8666133411978338 0.3861539012053643 1.0 0.6989794739829781 53 P42785,P53985,Q06481 3 +Galactose metabolic process 0.6188558321168351 0.8647960513652602 0.3871507388069004 1.0 0.7004666999902597 4 P15291 1 +Astrocyte differentiation 0.4630319408731118 0.8631150474788488 0.3880742154126704 1.0 0.7015025765856275 13 P05067 1 +Response to oxygen containing compound 0.3504989338949363 0.8615315231178361 0.3889453671276679 1.0 0.702886623588731 311 Q9BSK2,Q99720,Q9HCL2,Q8WTV0,O94788,P14174,Q13126,P39210,Q9UQB8,P05067,P16278,P11717,O95563,P11166,P22466,Q06481,O95831,O75116,O43865,Q96RR1,O75592,Q92542,Q14457,P43490,Q13464,Q01664,Q9Y4G8,Q13573,P09493,P78536,Q7L576,P11274,Q9NRA0,Q9BRK5,P08670,Q9NWH9,Q99523,P25705,Q9NS86,P07196 40 +Regulation of sequestering of triglyceride 0.6379120879120891 0.8595842184712266 0.3900182774308975 1.0 0.7038050448384034 3 O60664,Q9BZF1 2 +Sequestering of triglyceride 0.6379120879120891 0.8595842184712266 0.3900182774308975 1.0 0.7038050448384034 3 O60664,Q9BZF1 2 +Positive regulation of mitochondrial fission 0.477065342044439 0.8590194581576767 0.3903297808257422 1.0 0.7038612529477456 10 Q9NQG6,Q9Y3D6,Q96HS1,P11233,Q9GZY8 5 +Histone h3 k9 acetylation 0.617190532198086 0.8583943516578553 0.3906747454604713 1.0 0.7042927026523593 4 Q9NRA0 1 +Embryonic hemopoiesis 0.6171110224986298 0.8580888976814016 0.3908433773921134 1.0 0.7044061194383694 4 Q13043,Q13769 2 +Response to estrogen 0.4618131603821333 0.8565742723495334 0.3916802093476419 1.0 0.7055210857156707 13 P22466,P09601,Q969T9,P35221 4 +Fatty acid derivative biosynthetic process 0.4197794546046747 0.8544940590274703 0.3928312997761614 1.0 0.706650904537949 17 Q9UMR5,P50897 2 +Positive regulation of actin filament polymerization 0.4666413881071007 0.8537607816826536 0.3932375485908626 1.0 0.7069828089347354 12 Q9UQB8 1 +Regulation of myotube differentiation 0.5870726476317802 0.8529145880037876 0.3937066712676853 1.0 0.7069828089347354 5 P42345,Q96TA1 2 +Negative regulation of cellular catabolic process 0.3292262592226164 0.8528827666948045 0.3937243193429913 1.0 0.7069828089347354 96 P46379,O60506,P98175,O15118,Q07820,P35637,Q92804,Q9H7Z3,Q9Y2W1,A2RRP1,Q9NZI8,Q08379,P09601,Q9H2J4,P10619,Q14457,Q13464,P31749,Q13151,Q9H814,Q9NWH9,Q93009,Q96HY6,Q9NZM5,Q9H2U1 25 +Synaptic transmission glutamatergic 0.5261084593131783 0.8525486937466886 0.3939096248707903 1.0 0.7069828089347354 7 Q9BQT9,Q15042,P51790 3 +Cellular response to leucine starvation 0.6152847885654196 0.851077988714469 0.3947260317172218 1.0 0.7077662942227796 4 Q9P2X3,Q9P2J5 2 +Regulation of heterotypic cell cell adhesion 0.6151678964377826 0.850629567275295 0.3949751595307085 1.0 0.7078320301111111 4 P41440 1 +Maintenance of cell number 0.3809427070149075 0.8499840647004805 0.3953339458502307 1.0 0.7080928677555943 31 Q9UQE7,Q9NZI8,Q5UIP0,Q5TAX3,O75175,Q8IY18,P35222,Q86VS8,Q14683,Q92541,P19022,Q6PD62,Q15061,Q8N7H5 14 +Regulation of cell development 0.3277926724385202 0.8496301486222371 0.3955307447520781 1.0 0.7080928677555943 101 Q06481,Q96TA1,Q8N0X7,Q13464,Q96N67,O43707,O75116,Q9Y4G8,Q13049,Q13573,Q7L576,Q9UQB8,Q96G23,P07196,Q14185 15 +Attachment of mitotic spindle microtubules to kinetochore 0.4922636624574151 0.8487055157340234 0.3960451762559389 1.0 0.7087964032751333 9 Q96EE3,Q9Y6D9,Q14457,Q96DB5 4 +Epidermis development 0.3391525823837908 0.84713058234451 0.3969223405991995 1.0 0.7101653544524358 52 P22466,Q16739,P16615,Q13464,O75116,O75844,P11274 7 +Regulation of neuron projection arborization 0.6142082102522426 0.846949527795521 0.3970232545903231 1.0 0.7101653544524358 4 Q9HCE1,Q9UPN3 2 +Cartilage development 0.4398025236113141 0.8440151968649645 0.3986609136139969 1.0 0.7115675393503705 15 Q92896,O75844,Q9NX62 3 +Transmission of nerve impulse 0.4909540579439808 0.8424890857355923 0.3995142463643049 1.0 0.7119870284920922 9 Q06787,P42345,P17301,Q7Z406,P04062,Q9BX67 6 +Positive regulation of phospholipid biosynthetic process 0.6332417582417595 0.8419494170059988 0.3998162676501238 1.0 0.7122929923403142 3 Q9UHD1,P17655 2 +Regulation of myelination 0.4906769335821576 0.8411743709408306 0.4002502560892866 1.0 0.7127341931833924 9 Q7L576,Q96P11,P35222,P31749 4 +Export from cell 0.3037704470685541 0.8411250992074026 0.400277855454338 1.0 0.7127341931833924 164 Q4J6C6,P30511,P14174,Q7L0J3,P35579,O95563,P20645,P22466,P53985,P16615,P80404,O75592,O14936,Q16850,P55011,P50897,Q96TA1,O14523,P11274,Q9NRA0,Q9BRK5,P35580,P51809,Q13555,Q86YV9,O95219 26 +Negative regulation of regulated secretory pathway 0.5225714771178177 0.837136364899757 0.4025159217293161 1.0 0.7157629000486879 7 P11274,P30511 2 +Ruffle assembly 0.4632712156673454 0.836153435283923 0.4030685904740241 1.0 0.716172271554246 12 P84095,Q8NCA5 2 +Organelle membrane fusion 0.3654023751122731 0.8354261378857873 0.4034778182157286 1.0 0.7167082652016528 35 O60499,Q8WUH2,Q15075,P51809,P31751,O43752,Q9BZG1,Q969M3 8 +Regulation of the force of heart contraction 0.5821678526159257 0.8334512573383689 0.4045902768394076 1.0 0.7178381040754718 5 P16615 1 +L amino acid transport 0.4574761437853581 0.8333408094348357 0.404652546736826 1.0 0.7178381040754718 13 P30825 1 +Cellular response to ketone 0.4007396509049466 0.8330086143226766 0.4048398709880827 1.0 0.7179112091719334 23 P26038,Q01664,O95831,O75116,P25705,Q9NRA0 6 +Nuclear chromosome segregation 0.3177767754497247 0.8326489293006375 0.4050427552085507 1.0 0.7179112091719334 119 Q13123,P23246,P46379,Q8NBT2,Q96EE3,Q9HD42,Q8N3U4,Q02241,Q8WVM7,O95347,Q9NTJ3,Q12834,P50748,Q9Y6D9,Q14683,Q9NTI5,Q14807,O60566,Q8IY18,P12270,Q15021,Q14457,Q96DB5,Q9BTX1,Q9NZZ3,Q8WXW3,Q9UJX3,Q96EA4,Q9Y448,Q29RF7,O95239,P35222,Q9UQE7,Q96IY1,Q9Y6A5,Q9HC35,O43663,Q9BS16,Q9UIG0 39 +Peptidyl lysine acetylation 0.3372833877419904 0.8325036113922923 0.4051247405802896 1.0 0.7179112091719334 54 Q8IY18,P46379,Q9UPT9,Q9NRA0 4 +Ether biosynthetic process 0.5811922898453015 0.829588773125546 0.4067713264694466 1.0 0.7202544109130806 5 O00116 1 +Positive regulation of actin nucleation 0.6095941451936417 0.8292947679508862 0.4069376307604981 1.0 0.7203574478632304 4 Q7L576,P14373 2 +Negative regulation of fatty acid metabolic process 0.470377444693373 0.8257160559965788 0.4089651820874698 1.0 0.7226027600765874 10 Q8WXW3,P49748,Q06481 3 +Response to nutrient 0.3649817904379734 0.8237921262675759 0.4100576822216482 1.0 0.7237653871901567 34 O94788,P53985,Q13573 3 +Regulation of neutrophil migration 0.486936933920934 0.8234574315333055 0.4102479150307332 1.0 0.7238411726784517 9 O94813,P84095,Q8NHP6,P63000,Q00013,Q9BX67 6 +Protein localization to golgi apparatus 0.4607758957913774 0.8231432661356107 0.4104265271468093 1.0 0.7238411726784517 12 Q92538,Q5THJ4,Q8IWJ2,Q8TD16,Q8N2H4,O14976 6 +Regulation of response to interferon gamma 0.6276829416530666 0.8210482064320315 0.4116188101262874 1.0 0.7253679269694402 3 Q16543 1 +Positive regulation of brown fat cell differentiation 0.6274725274725286 0.8202590154092694 0.4120684652347608 1.0 0.7259683193704949 3 Q92766,Q16539 2 +Lung alveolus development 0.5787186515847591 0.8198086016991715 0.4123252266830828 1.0 0.726228650644827 5 P00813 1 +Oocyte construction 0.6267643533994405 0.8176039808030221 0.4135833537368936 1.0 0.7279945990461948 3 Q8N2A8 1 +Response to peptide hormone 0.3268625334955369 0.8174774280891551 0.4136556434022052 1.0 0.7279945990461948 92 Q9BSK2,P11166,P22466,Q06481,P43490,Q13464,Q99523,O75116,O43865,Q7L576,Q9UQB8,P07196 12 +C4 dicarboxylate transport 0.4853116834081084 0.8157740752483351 0.4146293632629225 1.0 0.7289859383559064 9 Q15758,P55011,P80404,Q9UBX3 4 +Smooth muscle cell proliferation 0.4009970413190946 0.8157265209369954 0.4146565670672197 1.0 0.7289859383559064 20 Q53EL6,Q14344,P09601,P17301,P31749,O95140,P42224,P12956,P09493,P35222 10 +Neuromuscular junction development 0.4639550859116451 0.8150931005660244 0.4150190206276432 1.0 0.729430687006591 11 P05067,P49354,Q14203 3 +Regulation of defense response 0.3248530708637877 0.8125036749285939 0.4165026787383148 1.0 0.7308815771486414 101 P30511,P60900,P05067,P19474,Q06481,Q9BY67,P28070,Q7Z434,P00813,O43657,O94874,Q15046,Q15233,P12956,P11274,P51809,Q9NZ08,O95219,O75844,P23246 20 +T cell lineage commitment 0.6051112943116347 0.8122057373973198 0.4166735879346224 1.0 0.7309370975918855 4 P42345,P40763,P04637 3 +Retrograde axonal transport 0.4844941854356844 0.8119130945856596 0.4168415001291414 1.0 0.7309370975918855 9 Q14168,P07196 2 +Negative regulation of fatty acid oxidation 0.6050243378581774 0.8118748961693071 0.4168634205086545 1.0 0.7309370975918855 4 P49748,Q06481 2 +Protein demethylation 0.50085571992483 0.8113920694305076 0.4171405519910607 1.0 0.7312256912471858 8 Q8NB78 1 +Sulfur compound metabolic process 0.3207755200876805 0.8097015438325195 0.4181117305157606 1.0 0.732162538876876 111 P16278,O95563,Q9HCL2,Q9UBX3,P50897,Q9NX62,Q9Y5Y2,Q9UMR5,O43505,Q13126,O75027,O43865,P00390,P32929 14 +Renal vesicle development 0.6241455391295968 0.807800408154889 0.4192054901393376 1.0 0.7329591678283884 3 P35222 1 +Nephron tubule epithelial cell differentiation 0.6241455391295968 0.807800408154889 0.4192054901393376 1.0 0.7329591678283884 3 P35222 1 +Regulation of epithelial cell differentiation involved in kidney development 0.6241455391295968 0.807800408154889 0.4192054901393376 1.0 0.7329591678283884 3 P35222 1 +Embryonic morphogenesis 0.3261943954465679 0.8077269144086863 0.4192478062507485 1.0 0.7329591678283884 89 P07942,O15078,Q9NX62,O94788,Q13464,O75116,P11274,P42892,Q8N3R9,P54802,Q9Y366,Q9NUN5 12 +Transport along microtubule 0.3341872110930144 0.8073815526645168 0.4194466917198927 1.0 0.7329591678283884 56 O60313,P23246,Q9Y496,A0AVF1,Q8TD16,Q14203,Q14168,Q9Y678,Q9NXR1,P07196,Q9Y366,O43805,Q9UPN4,P05067,Q5SNT2,P33176 16 +Regulation of signaling receptor activity 0.4219662053102946 0.801098398851788 0.4230746830806033 1.0 0.737944139624623 16 P05067 1 +Regulation of hormone secretion 0.3611302338715379 0.8005647081191911 0.4233836887342483 1.0 0.7381904938253436 35 O95563,P22466,P51809,P80404,P53985,O95219,Q9BRT2,O14523 8 +Positive regulation of hormone secretion 0.3983558167116233 0.7984798543008189 0.424592079325818 1.0 0.7394568156098619 20 O95563,P22466,P80404,O95219,O14523 5 +Autophagosome maturation 0.3929693501182786 0.7984267961803511 0.4246228583281903 1.0 0.7394568156098619 25 P51809,Q9HD42,P16615,Q8NHS3,Q14457 5 +Endothelial cell development 0.3965783741565838 0.7976877420353442 0.4250517190133229 1.0 0.7394568156098619 22 O75116,Q9Y4G8,Q13464,Q9NWH9 4 +Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules 0.601168080229563 0.7972286156564311 0.4253182696889934 1.0 0.7395343504534874 4 P19022,Q9BY67 2 +Positive regulation of small molecule metabolic process 0.4209923818833786 0.7953388972268254 0.4264163928677436 1.0 0.7408637355091984 16 P31751,Q92604,P05067,P00403 4 +Regulation of protein maturation 0.4553375281210472 0.7948734221241883 0.4266871359544089 1.0 0.7411408724880674 12 Q9Y366,Q9BXS4,Q92896 3 +Protein targeting to membrane 0.3504525737408479 0.7912888106113702 0.4287754764382436 1.0 0.7440296467977229 42 P46379,O43681 2 +Negative regulation of developmental process 0.319340059700037 0.7907570657772424 0.4290857684221496 1.0 0.7440296467977229 111 P14174,Q96G23,P05067,Q06481,Q8N0X7,P02786,O75116,Q15375,P55011,Q96TA1,Q13464,O43707,Q9Y4G8,Q8WX92,P11274,Q15051,Q99523,P57105,Q99538 19 +Mitotic sister chromatid segregation 0.3245586384531514 0.7904867140194666 0.4292435783116384 1.0 0.7440296467977229 93 Q13123,Q96EE3,Q9HD42,Q02241,O95347,Q9NTJ3,Q12834,P50748,Q9Y6D9,Q14683,Q9NTI5,Q14807,O60566,Q96JM3,Q8IY18,P12270,Q15021,Q14457,Q96DB5,P30260,Q9NZZ3,Q8WXW3,Q9UJX3,Q96EA4,Q9Y448,Q29RF7,Q15003,O95239,Q9UQE7,Q86XI2,Q96IY1,Q9Y6A5,Q9HC35,O43663,Q9BS16,Q9UIG0 36 +Dendrite self avoidance 0.6192307692307706 0.789466360329055 0.429839483615249 1.0 0.7442731443388316 3 Q8WX93,P35613 2 +Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway 0.4199687712268308 0.7892899344071639 0.4299425682965876 1.0 0.7442731443388316 16 Q92896,P78536 2 +Muscle tissue development 0.3315186574660718 0.7882451531245639 0.4305533223547468 1.0 0.744556653737264 58 O94788,O75844,Q7Z406,P02545,O75955,P09493,P41440,Q8NDZ4 8 +Fatty acyl coa metabolic process 0.4085834810547802 0.7855094978614269 0.4321549038208898 1.0 0.7465512377906633 17 P50897 1 +Regulation of protein localization to membrane 0.3376763803790654 0.784534591963051 0.432726492579033 1.0 0.7467903102463973 48 P27105,P84095,Q13136,Q01082,Q9BXS4,P31751,O15400,Q9GZY8,P33176 9 +Regulation of fatty acid oxidation 0.4945322888772828 0.7829867613129977 0.4336348862642873 1.0 0.748138075395895 8 P31751,P49748,Q06481 3 +Defense response 0.3287851185279951 0.7821075176310738 0.4341513890632777 1.0 0.7488352848378513 240 P42785,Q9HCL2,Q08380,P30511,P14174,Q5KU26,P14373,Q9NY93,P05067,P60900,P19474,P22466,Q06481,Q9BY67,P28070,P02786,P00813,Q9BPX6,Q13049,Q14457,P33176,Q8IV08,O60858,P12956,P78536,P11274,O00584,P08670,Q9NZ08,P15291,O95219,O75844,P23246 33 +Regionalization 0.3679604118508645 0.7803648049216206 0.4351761778768539 1.0 0.7494566427964566 32 Q9Y366,O94788,Q8N2A8 3 +Negative regulation of release of cytochrome c from mitochondria 0.4777766644468866 0.7802867117917197 0.4352221325980654 1.0 0.7494566427964566 9 P02545,O60313,Q9H300,P31749 4 +Ras protein signal transduction 0.3226153258061907 0.7802178963454436 0.4352626300901292 1.0 0.7494566427964566 78 Q15555,P84095,Q86VI3,Q07960,Q15392,Q13464,Q9NWH9,O75116,Q9Y4G8,P57105,Q9UBT7,O75955,Q7L576,P41440,P11274 15 +Response to interferon gamma 0.3875370948650564 0.7785247955287659 0.4362596948100519 1.0 0.7501984435682489 26 P08670,P19474 2 +Sensory organ development 0.3202672475190972 0.7784945241442139 0.4362775335566042 1.0 0.7501984435682489 71 Q15555,O15078,P08670,O94788,P42892,P39210,P54802,P11274,Q9Y6M7 9 +Muscle hypertrophy in response to stress 0.5680738220122623 0.7779577439622812 0.4365939247338937 1.0 0.7503289451900784 5 P16615 1 +Golgi to vacuole transport 0.4933579118526567 0.7777290223449502 0.4367287789212895 1.0 0.7503671619269086 8 Q99523 1 +Receptor clustering 0.428006621430243 0.7766545688335442 0.4373625973570916 1.0 0.7506818614606648 15 O43805,Q14168,P49354 3 +Anterior posterior pattern specification 0.3920626594171968 0.774556671973667 0.4386016683290972 1.0 0.751453565460729 23 O94788 1 +Negative regulation of secretion 0.389079541202795 0.771683018993955 0.4403021905571436 1.0 0.7541731351368247 25 P00813,P11274,Q16850,P30511 4 +Regulation of inflammatory response 0.3527969073688342 0.7714813570405805 0.4404216685157593 1.0 0.7541839057621446 39 P51809,P28070,P05067,O95219,P00813,P11274,P60900,O94874 8 +Homeostasis of number of cells 0.3245927066959677 0.7704693645641393 0.4410215208660228 1.0 0.7550170589748999 66 Q9HCL2,P14174 2 +Positive regulation of mirna transcription 0.5935696619950607 0.7685225473825954 0.4421768004679673 1.0 0.7566060661320151 4 P51532,P40763,P04637 3 +Intermediate filament bundle assembly 0.6133753319680411 0.7677387810302767 0.4426423913133042 1.0 0.7572082806984712 3 P07196 1 +Cell chemotaxis 0.3419945512743875 0.7652249419621273 0.4441376099038954 1.0 0.7587920243050397 45 P55011,Q99538,P84095,Q96JJ3,Q9NWH9,P14174,Q13641,P78536,Q9BX67 9 +Leukocyte degranulation 0.4352243907212995 0.7632185085236954 0.4453330924308352 1.0 0.7595419209611077 14 Q9NRA0,P11274,P30511,O95219 4 +Neuron projection regeneration 0.4536939802954081 0.7632101761353761 0.4453380608946924 1.0 0.7595419209611077 11 P07196,P10586 2 +Muscle adaptation 0.3927356214565272 0.7619109577133525 0.4461131495816788 1.0 0.7596350410587084 20 Q13555,P16615,P02545,O75116,Q14457 5 +Antigen processing and presentation 0.3823484913896188 0.7613109047098922 0.4464713888198282 1.0 0.759672414914959 27 P10321,Q9UIQ6,Q9NZ08,P30511,P61020,Q9BZG1,Q99538 7 +Amyloid beta metabolic process 0.4252498116437149 0.7610066696878977 0.4466530835182722 1.0 0.759672414914959 15 O75116,Q92542,Q13464,Q14457 4 +Response to gamma radiation 0.4044952786151833 0.7604762447667046 0.4469699635595163 1.0 0.759672414914959 17 O60858,P12956 2 +Regulation of skeletal muscle cell differentiation 0.5913712558395225 0.7602571747526261 0.4471008750248495 1.0 0.759672414914959 4 Q9BYT8,Q92841,Q9BRT2 3 +Smooth muscle cell apoptotic process 0.473206593019316 0.7588798871028608 0.4479244114742648 1.0 0.7601936713329157 9 Q8NDZ4 1 +Positive regulation of defense response 0.3348346603084781 0.7578212850536507 0.4485579781962543 1.0 0.7610750722489541 48 Q15046,Q15233,Q9BY67,P51809,Q7Z434,P30511,P12956,O95219,P05067,P23246 10 +Regulation of antigen receptor mediated signaling pathway 0.5039118014816109 0.7565607533556273 0.4493130617367717 1.0 0.7619681675622576 7 P00813 1 +Cellular response to glucose starvation 0.4339442946017157 0.7562150630816455 0.4495202629827206 1.0 0.7621255756371165 14 P11166,P54619,Q14457 3 +Cardiac muscle tissue development 0.3555456107887168 0.7552085004457576 0.4501238890759074 1.0 0.7625668631865677 35 O94788,O75844,Q8NDZ4,P09493 4 +Positive regulation of connective tissue replacement 0.6090793059548685 0.7518821250045454 0.4521219485249266 1.0 0.764009267821858 3 O75116 1 +Connective tissue replacement 0.6090793059548685 0.7518821250045454 0.4521219485249266 1.0 0.764009267821858 3 O75116 1 +Positive regulation of tissue remodeling 0.6090793059548685 0.7518821250045454 0.4521219485249266 1.0 0.764009267821858 3 O75116 1 +Regulation of connective tissue replacement 0.6090793059548685 0.7518821250045454 0.4521219485249266 1.0 0.764009267821858 3 O75116 1 +Negative regulation of apoptotic signaling pathway 0.3180907979423094 0.7495666442778183 0.4535157464235064 1.0 0.7659760249479907 72 O60313,Q96K76,Q9H3K2,P35221,Q15233,Q9H300,P09601,Q07820,Q8N2F6,Q7LG56,P45880,P14174,P02545,Q13049,P32929,P26583,P31749 17 +Fatty acyl coa biosynthetic process 0.4416288076886797 0.7490997874049907 0.4537970631676056 1.0 0.7662569264789042 13 P50897 1 +Regulation of body fluid levels 0.3280151552963629 0.7486845585614906 0.4540473527805599 1.0 0.766485308228242 57 P35579,P12814,Q9UNS2,Q16739,P80404,Q9NWH9,P61201,Q13505,P00813,O75592 10 +Negative regulation of endothelial cell proliferation 0.560195513901141 0.7472539612583442 0.4549102770490494 1.0 0.7673587787285611 5 P25705 1 +Positive regulation of hydrolase activity 0.3187232695919249 0.746171121082033 0.455564050886474 1.0 0.767415675816573 104 P84095,Q96N67,P05067,O95831,O75116,Q92542,P07602,Q13464,Q01664,Q9Y4G8,Q96F07,Q9BXK5,P11274,Q15555,P49354,Q9Y5X1,Q96A26,P31751,Q96HY6 19 +Regulation of tube size 0.4410031786143456 0.7457983904469193 0.4557892124079226 1.0 0.767415675816573 13 O75116,Q9HB40,P42892 3 +Positive regulation of smooth muscle cell proliferation 0.4541139547708748 0.7454696382912056 0.455987859082982 1.0 0.767415675816573 10 P09601,P42224,P31749,O95140 4 +Bleb assembly 0.5873869577090169 0.7453255814947047 0.4560749199496152 1.0 0.767415675816573 4 Q9NR77 1 +Axo dendritic transport 0.3799653781929266 0.7444827233860843 0.4565844894043009 1.0 0.7678501900305041 27 O60313,Q9Y496,Q14203,Q14168,P07196,P05067,P23246,P33176 8 +Response to dsrna 0.412282343064476 0.744044052588957 0.4568498245924188 1.0 0.7679059696500826 16 Q7Z434,Q5KU26,O75955,Q9NY93,P41440 5 +Microtubule based transport 0.3274787028360664 0.7432772096776284 0.4573138665808434 1.0 0.7679059696500826 57 O60313,P23246,Q9Y496,A0AVF1,Q8TD16,Q14203,Q14168,Q9Y678,Q9NXR1,P07196,Q9Y366,O43805,Q9UPN4,P05067,Q5SNT2,P33176 16 +Glycerol ether metabolic process 0.5007680135021573 0.7431234946349339 0.45740691646903 1.0 0.7679059696500826 7 O00116,Q6PIU2 2 +Positive regulation of smoothened signaling pathway 0.5000335417448953 0.7399905885975289 0.4593057049867766 1.0 0.7684163231868345 7 Q86SX3,Q9BZG1 2 +Heart valve development 0.5000191381499068 0.7399291743833339 0.4593429709219814 1.0 0.7684163231868345 7 O75116,O94813,Q13464,P43243 4 +Regulation of leukocyte chemotaxis 0.3895262026204718 0.7379469649451119 0.4605466778934683 1.0 0.7692272689012183 19 P78536,Q9BX67,P14174 3 +Response to corticosteroid 0.3730417942253066 0.7378258150473445 0.4606203039570808 1.0 0.7692272689012183 29 P16278,O95831,P25705,O75592,P07196 5 +Negative regulation of organic acid transport 0.5576815483895007 0.7375091608054928 0.4608127743700354 1.0 0.7692272689012183 5 P31751,P80404,P31749 3 +Regulation of protein localization to plasma membrane 0.3729789553932732 0.7373680939265363 0.4608985328419648 1.0 0.7692272689012183 29 P84095,Q13136,Q01082,Q9BXS4,O15400,P33176 6 +Positive regulation of secretion 0.325023525440816 0.7370057581989549 0.4611188476720382 1.0 0.7692626144313448 61 O95563,P55011,P35580,P22466,P80404,P30511,P14174,O95219,O14523,Q9NRA0 10 +Mitochondrial fission 0.4108859211954334 0.7358601663271904 0.4618158010851521 1.0 0.770075057773769 16 O60313,Q9NUQ9,Q9NQG6,Q9Y3D6,Q96HS1,P11233,Q9GZY8 7 +Innate immune response 0.2985075529375449 0.7339336933326494 0.4629891508378208 1.0 0.7715416353527244 134 P19474,Q06481,O00584,P08670,Q9BY67,Q9NZ08,P30511,P14174,O60858,Q5KU26,P14373,P12956,Q9NY93,Q13049,P23246,P33176 16 +Outflow tract septum morphogenesis 0.5421587475968058 0.7322875422469263 0.4639930814362794 1.0 0.772703299577588 2 Q9NVD7 1 +Myeloid leukocyte differentiation 0.3684412233028267 0.7283012478085951 0.4664291986691684 1.0 0.775016895444556 30 P35579,P02786,O00625,Q14739,Q13769,P04062,P05067 7 +Gmp metabolic process 0.3991517675287008 0.7279054003847397 0.4666714971269097 1.0 0.7752261743596607 17 P00813,P55263 2 +Negative regulation of receptor mediated endocytosis 0.442270750069804 0.7274984274964017 0.4669206782854163 1.0 0.7754027752101263 12 P30533,P05067 2 +Fat soluble vitamin metabolic process 0.4970037649762349 0.7270934371199331 0.4671687188408024 1.0 0.7754721409158613 7 O94788,Q8N0U8 2 +Response to abiotic stimulus 0.3250249659207584 0.7259057683742298 0.4678965400386405 1.0 0.7757219776977131 239 P22830,P27544,P30519,P02545,P05067,P55786,Q13432,Q00796,P11166,P49748,Q06481,Q9Y487,P02786,P80404,Q70UQ0,O95831,O75116,P00813,Q9BPX6,O75592,Q13049,Q14457,P00403,P55011,O95155,Q15046,Q9P2X3,Q16576,P00846,O43707,O60858,P12956,Q13330,P51798,O15287,P78536,Q7L576,P31749,Q9BRK5,Q15555,Q96K76,Q9UNS2,P17655,Q96A26,O75306,P31751,Q9H2U1,Q99538,O75844 49 +Rna polyadenylation 0.3526463827955632 0.7246337921890371 0.4686767222601347 1.0 0.776354462012707 34 P05067,O43865 2 +Rna phosphodiester bond hydrolysis endonucleolytic 0.3496444889388442 0.7242088573398406 0.4689375216203946 1.0 0.776354462012707 37 Q9UQ84,Q8N2A8 2 +Inner mitochondrial membrane organization 0.3844891041998317 0.723923785723218 0.4691125263608464 1.0 0.776354462012707 23 O60313,Q16891,Q9H3K2,Q9Y4W6,Q13505,O75431,Q9NX63 7 +Membrane lipid catabolic process 0.4413121663582756 0.7225902885298153 0.4699316364387524 1.0 0.7766175099979776 12 P06280,P50897 2 +Lipid biosynthetic process 0.2971725053377272 0.7211169137940134 0.4708375854998536 1.0 0.7768297395555095 166 O00116,P54619,Q9HCL2,P27544,Q8WTV0,O94788,Q96PE3,P14174,Q9H1P3,Q9UBM7,Q96G23,Q8NCC3,Q99805,Q9BXW7,Q9UKU0,P49748,Q15392,Q14739,P35790,Q9Y6K0,Q9UHI6,O75592,Q5H8A4,Q969N2,Q14457,Q16850,Q8NBX0,Q8WXW3,Q8WUK0,Q92604,Q16739,O60512,Q9NRA0,P31749,Q9H4L5,Q96N66,Q96PU8,Q9NX62,P17655,Q9NPH0,Q9H3P7 41 +Purine nucleotide transport 0.4180217479743827 0.7201794629232838 0.4714145069232689 1.0 0.7771478979198291 15 Q86VD7,P41440,Q8TB61 3 +Positive regulation of rna export from nucleus 0.5803710135141884 0.7191913150935862 0.4720230498225064 1.0 0.777686597136935 4 Q9H7Z3 1 +Positive regulation of nucleobase containing compound transport 0.5803710135141884 0.7191913150935862 0.4720230498225064 1.0 0.777686597136935 4 Q9H7Z3 1 +Sister chromatid segregation 0.316463386498242 0.7174571493164247 0.4730920675478116 1.0 0.7785162870019928 104 Q13123,P23246,Q96EE3,Q9HD42,Q8N3U4,Q02241,Q8WVM7,O95347,Q9NTJ3,Q12834,P50748,Q9Y6D9,Q14683,Q9NTI5,Q14807,O60566,Q96JM3,Q8IY18,P12270,Q15021,Q14457,Q96DB5,P30260,Q9NZZ3,Q8WXW3,Q9UJX3,Q96EA4,Q9Y448,Q29RF7,Q15003,O95239,P35222,Q9UQE7,Q86XI2,Q96IY1,Q9Y6A5,Q9HC35,O43663,Q9BS16,Q9UIG0 40 +Camera type eye development 0.3433487614065127 0.7157487582474018 0.4741464979561245 1.0 0.7798662344807844 41 Q15555,O15078,P08670,O94788,P54802 5 +Antigen processing and presentation of endogenous antigen 0.4478853772720138 0.7150693384483732 0.4745661990522274 1.0 0.7801713753478883 10 P30511,Q9NZ08,P10321 3 +Negative regulation of nf kappab transcription factor activity 0.3856075447255227 0.7110854856208709 0.4770312636735312 1.0 0.7828717511962411 18 Q93009,P19474,O60826,O94874 4 +Meiotic cell cycle process 0.3440221318324222 0.7090478246786968 0.4782947992281547 1.0 0.7839798886241562 40 P35579,P46379,O60566,Q9BTX1,Q08379,Q92878,Q9NTJ3,Q12834,Q9Y2W6 9 +Protein tetramerization 0.3582340129450704 0.7055113841032078 0.4804920499383729 1.0 0.7858612926250079 32 Q06481,Q08379,O94788,Q15070,P31350,Q9H9S5,P32929 7 +Myeloid cell activation involved in immune response 0.4379054676935667 0.705189665466896 0.4806922117959358 1.0 0.7858612926250079 12 Q15046,P51809,O95219,P11274,Q9NRA0 5 +Regulation of phospholipid biosynthetic process 0.5490152523639924 0.7041273991624575 0.4813534384838274 1.0 0.7858612926250079 5 Q9UHD1,P17655,O95573 3 +Amine transport 0.4761062069960939 0.7012172377460428 0.4831674538532984 1.0 0.7875330210139321 8 Q7L0J3,P80404 2 +Ear morphogenesis 0.3836705710199939 0.6988766558976656 0.4846291174234798 1.0 0.7892154408888437 18 P11274,P54802,O15078 3 +Striated muscle cell differentiation 0.323995795721389 0.6987840218254636 0.484687015476084 1.0 0.7892154408888437 51 P35579,Q8IV08,O75844,P02545,Q99523,O75955,P09493,P41440,Q13049 9 +Stress granule disassembly 0.5943953799145941 0.6982737767678774 0.4850059954890708 1.0 0.7895418880878767 3 P33176 1 +Microtubule anchoring 0.4232078434941742 0.6978369248450661 0.4852791840606594 1.0 0.7896007822701279 14 Q9Y496,Q8IWJ2,Q8TD16,Q14203,O95684 5 +Calcium ion regulated exocytosis 0.4439720626152631 0.6960785884455566 0.4863796147713319 1.0 0.7905249573247205 10 Q9BRK5,P35579,P16615 3 +Cellular response to dexamethasone stimulus 0.4892228173194897 0.6941770636661316 0.4875711746867917 1.0 0.7913974998631165 7 P25705 1 +Dendrite development 0.3226558810372983 0.6919343432800188 0.4889785620074858 1.0 0.7928070548944133 56 Q14012,Q13641,Q9Y4G8,Q12834,Q96RK4,Q7L576,Q9UQB8,P05067 8 +Neural plate development 0.5925824175824189 0.6917229983153325 0.4891113012861787 1.0 0.7928070548944133 3 Q9HCM4,P35222 2 +Positive regulation of mitochondrial membrane potential 0.5722826612683569 0.6893318088606616 0.4906144850937424 1.0 0.7938232914472088 4 P31751 1 +Multicellular organismal homeostasis 0.31338149332261 0.688165449867719 0.491348598472773 1.0 0.7944632348184382 74 P42785,Q96H78,Q96N67,O14773,P11166,P49748,Q06481,Q9UIQ6,P02786,P80404,Q13049,P55011,P23786,Q16739,P51790,P78536,Q9BX67,Q15051,Q15555,Q9NWH9 20 +Carbohydrate derivative catabolic process 0.3428786411684648 0.688135112538437 0.4913677008384787 1.0 0.7944632348184382 39 P16278,Q9H773,Q9BTY2,Q13126,O60502,P54802,P00813,P06280 8 +Response to x ray 0.4341169935949074 0.6859204064145151 0.4927633011974786 1.0 0.7954868253297737 12 P12956 1 +Free ubiquitin chain polymerization 0.5908612338731013 0.6855185392843832 0.4930167658962494 1.0 0.7955850596189659 3 Q13049 1 +Gpi anchor metabolic process 0.4870038081886911 0.6848472756827187 0.4934402994488382 1.0 0.7960757179727869 7 Q969N2 1 +Response to wounding 0.315870717324315 0.6841044627699301 0.4939092040040029 1.0 0.7966393188764638 90 P35579,P12814,P42785,P55011,Q8WTV0,Q9HD42,P80404,Q86YV9,P15291,P10586,P78536,P09493,Q96G23,P07196,Q16625,O14936 16 +Protein stabilization 0.3147859283868012 0.682244450179094 0.4950843920318135 1.0 0.7967182756256252 81 P46379,P78371,O75569,Q9UNS2,O75718,Q9BZE4,O75955,Q9H2J4,O00291,P41440,Q6N069 11 +Regulation of leukocyte differentiation 0.3780369177055188 0.6811307723921756 0.4957887472209161 1.0 0.7967182756256252 23 P00813 1 +Mitochondrial transcription 0.4861022157896012 0.6810641835587832 0.4958308788463532 1.0 0.7967182756256252 7 Q9BSK2,O00411 2 +Response to insulin 0.3154569779164734 0.6810175242685763 0.4958604019278021 1.0 0.7967182756256252 67 Q9BSK2,P11166,P22466,Q06481,P43490,Q99523,Q7L576,Q9UQB8 8 +Regulation of histone h3 k36 methylation 0.5695121047666631 0.6791745140273101 0.497027293583733 1.0 0.7968736515763509 4 Q96L73 1 +Endoplasmic reticulum organization 0.3219014252911548 0.6791071666456372 0.4970699618955374 1.0 0.7968736515763509 50 P46379,O43681 2 +Regulation of actin filament bundle assembly 0.3617129264515082 0.6787120172786709 0.4973203503086041 1.0 0.7969325382650864 30 Q96RK4,Q9NWH9,Q13464,Q13136,O75116,P09493 6 +Nuclear migration 0.4193654670791685 0.6771180793310554 0.4983310388620618 1.0 0.7981259891408726 14 Q96N67,Q9UH99,Q14203 3 +Insulin secretion 0.3544505307807659 0.6766413083235427 0.4986335632482672 1.0 0.7981259891408726 32 Q13555,P53985,P22466 3 +Phospholipid biosynthetic process 0.3173431635606917 0.6764553220302094 0.4987516031614318 1.0 0.7981259891408726 64 Q96N66,O15228,Q9HCL2,Q9NX62,P17655,Q8WUK0,Q96PE3,Q92604,Q9NPH0,P35790,Q9Y6K0,Q14457,Q9NRA0,Q969N2,Q5H8A4,Q9BXW7 16 +Purine containing compound biosynthetic process 0.3145091693128364 0.6748781893942294 0.4997531585894625 1.0 0.798427467134831 83 O95563,P55263,P50897,P00846,Q9UMR5,Q13126,O75964,P00813,Q9NRA0 9 +Membrane protein intracellular domain proteolysis 0.5878745889675234 0.6747870944352055 0.4998110408853939 1.0 0.798427467134831 3 Q8TCT8 1 +Regulation of peptidyl serine phosphorylation 0.3698988316538438 0.6739155922119938 0.5003649785595821 1.0 0.7987811569460029 27 P14174 1 +Regulation of microvillus length 0.587500900619031 0.6734475289909017 0.5006626197179669 1.0 0.7988302287310377 3 P15311 1 +Membrane organization 0.3292229383491545 0.6730466551203498 0.5009176098026396 1.0 0.7988684637743033 265 Q92538,Q86XL3,P46379,Q8WUH2,O15118,Q9HD42,P84095,Q15629,Q9H1P3,P02545,Q13505,O14976,Q8N3R9,Q9UQB8,P35579,O60313,Q8N4V1,Q9UH99,Q06481,P16615,Q15392,Q14203,Q96GC9,Q15070,Q9BZG1,Q14457,Q96CP7,P20700,Q16891,O60499,P50897,P55735,Q16739,P45880,P51790,Q9Y4W6,Q9Y5Z4,O43752,O75431,O14523,Q8N1F7,O15400,P41440,Q969M3,P31749,Q14185,Q9NX63,Q15075,P49354,P61916,P51809,Q9Y5X1,Q15437,Q01082,P31751,O43681,O75955,O75844 58 +Positive regulation of erbb signaling pathway 0.4838907899788609 0.6718041367924267 0.5017083948352776 1.0 0.7995802653811688 7 P78536 1 +Peroxisome organization 0.4181048485782756 0.6703425140604367 0.5026394713432121 1.0 0.8000685135116631 14 O14678,Q9GZY8 2 +Regulation of smoothened signaling pathway 0.4307626868424911 0.668935361976774 0.5035367115275049 1.0 0.801113922852857 12 Q4G0X4,Q86SX3,Q9BZG1 3 +Cardiac chamber morphogenesis 0.4262052265589385 0.6683677037346141 0.5038989058082615 1.0 0.8014987847697413 13 O96028 1 +I kappab phosphorylation 0.48295962393862 0.6679132733171889 0.5041889541461053 1.0 0.801692410232373 7 Q8IUD2,Q96HY6 2 +Integrin mediated signaling pathway 0.3780243453913491 0.6672072428381995 0.5046397653768127 1.0 0.8017248602229823 20 P35579,P35221,Q96RT1,Q96AC1,P17301,Q14185 6 +Skeletal system morphogenesis 0.3783367542057662 0.6667823142665492 0.5049111911519621 1.0 0.8017691293244814 19 Q92896,O75844,Q9NX62 3 +Regulation of glycolytic process 0.4531794839246689 0.6663097249043068 0.5052131508926663 1.0 0.8019278082485298 9 P05067 1 +Embryo development 0.3143033087497379 0.6645356320803975 0.5063475511582487 1.0 0.8026280597552423 218 P07942,P46379,O94788,O43772,Q8N3R9,P54802,Q9Y366,Q96EK5,P35579,P49321,O75787,O75116,P42892,P00813,Q9Y2W6,Q8N2A8,O15078,P23786,Q96TA1,Q13464,P61201,P31350,Q14168,Q9BRT9,P11274,Q9Y3C6,Q9NX62,O75569,Q9UNS2,P17655,P57105,Q92541,Q96RK4,Q9H2U1,Q9NUN5,Q9UPT9 36 +Regulation of dna binding transcription factor activity 0.3122556380562341 0.6645275939880053 0.5063526939666168 1.0 0.8026280597552423 77 P23396,P60900,P19474,P31749,P02786,Q7Z434,Q8IUD2,O60858,P14373,Q93009,O75955,Q96HY6,O60826,P41440,P32929,Q13049,P05067,O94874 18 +Regulation of protein stability 0.3060815099239442 0.6642407381562162 0.5065362436246126 1.0 0.8026280597552423 118 P46379,P19474,P78371,Q96K76,O75569,Q9NVN8,Q9UNS2,Q96AB3,Q96HY6,O75718,P02545,Q9BZE4,O75955,Q9H2J4,O00291,P41440,P10619,Q6N069 18 +Centromere complex assembly 0.4335935668614508 0.6631305254878059 0.5072469619459561 1.0 0.803372119668625 11 Q9BS16,Q9H3R5 2 +Cellular hyperosmotic response 0.4817184091399548 0.6627346362398366 0.5075005226696645 1.0 0.8035826954724274 7 P11166 1 +Reactive oxygen species metabolic process 0.3242511400068091 0.6591776653596703 0.5097816873566252 1.0 0.805076728732635 48 Q9BSK2,P42785,Q13423,P51790,P39210,O75027,Q9NRA0,P11274,Q9H300,Q14457 10 +Inner ear morphogenesis 0.4327785541523661 0.6591243136685104 0.5098159437875183 1.0 0.805076728732635 11 O15078 1 +Establishment of protein localization to vacuole 0.3725074660947221 0.6590027371565054 0.5098940109938046 1.0 0.805076728732635 25 Q99523,P20645 2 +Adherens junction assembly 0.5370188015241611 0.6585086345414876 0.5102113505428003 1.0 0.8053869293216486 5 Q9BX67 1 +Regulation of er to golgi vesicle mediated transport 0.4801751553209701 0.6563083828920505 0.5116257249228489 1.0 0.807048790446039 7 Q969M3,Q9HCU5 2 +Sulfur compound biosynthetic process 0.3239000621514368 0.6559319638846381 0.5118679009162674 1.0 0.807048790446039 48 Q9UKU0,O95563,Q8NCH0,P50897,Q96L58,Q9UMR5,O43505,Q13126,P32929 9 +Amp metabolic process 0.397076495197124 0.6556321567767464 0.51206083003945 1.0 0.807048790446039 16 P00813 1 +Positive regulation of macroautophagy 0.3672510920710224 0.6555117546145919 0.5121383208102852 1.0 0.807048790446039 27 O60858,P21796,Q14457 3 +Positive regulation of endothelial cell proliferation 0.4279067146342865 0.6545330771265245 0.5127684240006596 1.0 0.8075721943112978 12 P78536,P31749,P26583,Q9H2J4 4 +Positive regulation of protein targeting to membrane 0.4316333592016532 0.6535027287395628 0.5134322308231511 1.0 0.8079137238809901 11 P31751,Q9GZY8 2 +Amino acid transmembrane transport 0.3966684345827324 0.6532830310018677 0.5135738299762869 1.0 0.8079137238809901 16 P30825 1 +Cellular homeostasis 0.2928660177758237 0.6525376823391331 0.5140543720465338 1.0 0.8079137238809901 166 Q9HC07,Q7L0J3,P10253,O75027,O75503,P00390,P05067,O95563,Q9NWR8,Q9Y487,P02786,P16615,O75787,Q14203,Q9HD20,Q9BPX6,Q96RR1,Q13049,P55011,P50897,P51790,Q93050,Q9Y6M7,Q9H4I9,Q9NWW5,O60826,Q8IYU8 27 +Dna methylation or demethylation 0.3712394758576854 0.6504810164624729 0.5153815601482086 1.0 0.8081871817527686 25 Q8NB78,Q8N2A8,Q96TA1,O75844,Q9Y2W6 5 +Positive regulation of cell morphogenesis involved in differentiation 0.3635337468428857 0.6482633111861059 0.5168146594276211 1.0 0.8092916746806673 28 Q9UQB8 1 +Deoxyribose phosphate metabolic process 0.3755449355032904 0.6479898878438803 0.5169914906796156 1.0 0.8093496286854567 18 P00813,Q9H773 2 +Cerebral cortex development 0.3505846051620142 0.647308213842829 0.5174324865577746 1.0 0.8095934850059765 32 P11166,P07942,Q96N66,O94813,Q9Y6A5,Q8N3R9,Q9NXR1,Q96RK4,P07196,P19022,Q9HCS7,P35222 12 +Regulation of immunoglobulin production 0.3955436565152767 0.646814958267117 0.5177517101400819 1.0 0.8095934850059765 16 Q96FV9,P02786,Q9NQT5,Q96FZ2,O96028 5 +Glycosylceramide catabolic process 0.5797571315187903 0.645851769219413 0.5183753574000711 1.0 0.8100222810404958 3 P06280 1 +Regulation of cation channel activity 0.3739616659109521 0.6413667087266106 0.5212844572789723 1.0 0.8136140404895273 20 P05067 1 +Adipose tissue development 0.412479931783385 0.6402503927434483 0.522009825965912 1.0 0.8139834941284512 14 P43490,Q8N0X7,O15173 3 +Negative regulation of exocytosis 0.432184356224861 0.6394476139742361 0.5225317825585689 1.0 0.8140384583958428 10 P11274,P30511 2 +Regulation of protein targeting to membrane 0.4246423003435812 0.6381414276747627 0.5233816210606901 1.0 0.8149782054515957 12 P31751,Q9GZY8 2 +Negative regulation of vasculature development 0.3937284243556267 0.6363987055376413 0.5245165843891471 1.0 0.8159659176906009 16 P55011,Q4VCS5,Q96TA1,Q13464,O75116,P57105,P35222 7 +Regulation of blood brain barrier permeability 0.5768771148499028 0.635670868149179 0.5249909679359313 1.0 0.8159659176906009 3 Q16625 1 +Positive regulation of vascular permeability 0.5768771148499028 0.635670868149179 0.5249909679359313 1.0 0.8159659176906009 3 Q16625 1 +Positive regulation of blood brain barrier permeability 0.5768771148499028 0.635670868149179 0.5249909679359313 1.0 0.8159659176906009 3 Q16625 1 +Response to mitochondrial depolarisation 0.4751938149057623 0.6356637154220908 0.5249956309679733 1.0 0.8159659176906009 7 P04062,Q14457,O95140 3 +Cell fate determination 0.5306309693146112 0.634526514007976 0.525737269029247 1.0 0.8165455297587368 5 Q07820 1 +Nucleus localization 0.4025494967977499 0.6339418282718476 0.5261187865007764 1.0 0.8165455297587368 15 Q96N67,Q9UH99,Q14203 3 +Isoprenoid metabolic process 0.3641271802889547 0.6338929850910676 0.5261506639162989 1.0 0.8165455297587368 27 O94788 1 +Negative regulation of neuron death 0.329009389710746 0.63327601702425 0.5265534119922932 1.0 0.8165455297587368 44 Q01105,Q15233,P50897,P09601,P30511,Q13464,P35222,Q99538,P04062,Q9UMX5,P07196,P31749 12 +Cdc42 protein signal transduction 0.517165613842342 0.63104362995993 0.528011997224481 1.0 0.8177926400527002 2 O14786 1 +Positive regulation of cysteine type endopeptidase activity 0.355002256608215 0.6297273298689771 0.5288729983362979 1.0 0.8181752467877299 30 P23396,Q01664,Q96A26,O95831,Q96F07,Q9BXK5,O00291 7 +Protein localization to presynapse 0.5749982050060989 0.6290539051946203 0.5293137662696608 1.0 0.8184770537606753 3 Q14168 1 +Axo dendritic protein transport 0.5749982050060989 0.6290539051946203 0.5293137662696608 1.0 0.8184770537606753 3 Q14168 1 +Negative regulation of g protein coupled receptor signaling pathway 0.4593615323779816 0.6284946002938038 0.5296799828372813 1.0 0.8185833977579655 8 P00813 1 +Embryonic heart tube development 0.4592924967146793 0.628198428187645 0.5298739598574373 1.0 0.8185833977579655 8 Q9Y366,P42892 2 +Thioester metabolic process 0.3312137194643696 0.6247972396990811 0.5321041425623543 1.0 0.8201272037689027 42 Q9UMR5,Q9HCL2,P50897 3 +Ventricular system development 0.4436123144873805 0.6229340149284799 0.533327884262695 1.0 0.8209888181050137 9 Q9Y4G8,Q96N66 2 +Negative regulation of telomere maintenance via telomerase 0.5005119751105331 0.6228205379655597 0.533402460389705 1.0 0.8209888181050137 6 Q9NVN8,P07910,Q9H0A0,Q00839 4 +Protein localization to extracellular region 0.3076677718232075 0.6199282647062627 0.5353050162044384 1.0 0.8227256527859269 75 O95563,Q16850,P55011,P20645,P22466,P35580,Q13555,P80404,P53985,Q86YV9,Q9BRT2,O14523,Q96KC8,O75592 14 +Amyloid beta formation 0.4209947796828804 0.6199195117122455 0.5353107791668439 1.0 0.8227256527859269 12 O75116,Q92542,Q13464 3 +Cellular response to nitrogen compound 0.2808790270861245 0.6173617643561146 0.5369961359660937 1.0 0.8234227161008876 145 Q9BSK2,Q5KU26,Q9UQB8,P05067,Q06481,Q7Z434,O95831,O75116,O43865,Q92542,Q9P2X3,P43490,Q13464,Q9Y4G8,Q7L576,P41440,P08670,P17655,P25705,P31751,O75955 21 +Cell cell signaling 0.3088513941233118 0.6172046301942014 0.5370997620785518 1.0 0.8234227161008876 211 Q4J6C6,Q9BQT9,P14174,Q7L0J3,Q9P1Z2,Q9BRT2,Q12834,Q9UQB8,P05067,Q13432,Q9NR77,O95563,P22466,Q9UIQ6,Q00536,P53985,P16615,O75787,P80404,Q92542,P33176,O14936,P48729,P55011,P50897,P43490,Q96TA1,P51790,Q13641,Q9Y4G8,Q14168,O14523,Q7L576,P41440,P11274,Q96K76,P51809,Q13555,P57105,O95219,Q92541,O75955,Q99538 43 +Monocarboxylic acid metabolic process 0.2940712860979929 0.6160143697111766 0.5378850358642007 1.0 0.8238914928650963 174 Q9H4L5,P21796,Q9HB40,O95563,Q9HCL2,P07099,Q06481,O94788,P14174,Q9BWD1,O14678,O15254,O75592,Q8NCC3,P05067,Q8N8N7 16 +Maintenance of synapse structure 0.4982989412385338 0.614238107508896 0.5390579949522494 1.0 0.8247401654114438 6 Q9BRK5,Q14203 2 +Prostanoid metabolic process 0.4074356011319346 0.6134734731384918 0.5395633175025778 1.0 0.8251476102631407 14 P14174 1 +Myeloid leukocyte migration 0.3581307507548476 0.6103841307284981 0.5416073779095969 1.0 0.827007089274891 28 Q99538,P84095,Q9BX67,P14174 4 +Mitotic dna replication 0.4260399721814614 0.6103095802980169 0.5416567518528628 1.0 0.827007089274891 10 O75844,Q14566 2 +Respiratory chain complex iv assembly 0.4405508482741228 0.6091881891325912 0.5423997080349938 1.0 0.8275725336929618 9 Q7KZN9,Q9Y2R0 2 +Negative regulation of telomere maintenance via telomere lengthening 0.4680951353571379 0.6065174561589076 0.5441711942959309 1.0 0.828860434475861 7 Q9NVN8,P07910,Q9H0A0,Q00839 4 +Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process 0.5683168077663575 0.6056896361562921 0.5447208673297943 1.0 0.8291500174320257 3 O75116 1 +Regulation of aspartic type peptidase activity 0.5683168077663575 0.6056896361562921 0.5447208673297943 1.0 0.8291500174320257 3 O75116 1 +Positive regulation of developmental process 0.3106089097544701 0.6053343932001269 0.5449568334374351 1.0 0.8291500174320257 218 Q9HCL2,Q9BQT9,Q86VI3,P02545,Q12834,Q9UQB8,P22466,Q8WUJ1,Q9H2J4,P00813,P32929,Q13049,Q8N2A8,Q9NZM3,Q96TA1,Q13641,Q9Y4G8,P12956,Q13573,O96028,P41440,Q14185,Q9NZ08,O75955,P07196,Q9GZY8 26 +Schwann cell development 0.453205417948028 0.6022138371047647 0.54703180618541 1.0 0.8306321312976538 8 P31751,Q8N3R9 2 +Establishment of cell polarity 0.3137743760442487 0.602169846286275 0.5470610852306799 1.0 0.8306321312976538 50 Q92538,P35579,Q9NUQ9,Q4VCS5,P26038,Q13464,Q96N67,Q14203,Q96L92,O75116,Q96EA4,Q9BX67 12 +Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.4530428180158754 0.601523340399463 0.5474914707136516 1.0 0.8306321312976538 8 Q9NZI8,O60506 2 +Crd mediated mrna stabilization 0.4530428180158753 0.6015233403994626 0.5474914707136518 1.0 0.8306321312976538 8 Q9NZI8,O60506 2 +Mitochondrial transport 0.3084632337674435 0.5974113192847338 0.5502327982880855 1.0 0.8320928586004342 95 P23786,P00846,O43772,P45880,O95831,P25705,O75431,O75964,Q9GZY8,P55786 10 +Regulation of dendrite development 0.3641442742573797 0.5961159633106162 0.5510977606557543 1.0 0.8328565269653715 24 Q9Y4G8,Q9UQB8,Q12834 3 +Schwann cell differentiation 0.437523824199976 0.5956655826595841 0.5513986548989867 1.0 0.8330996003609858 9 P31751,Q8N3R9,P31749 3 +Regulation of double strand break repair via nonhomologous end joining 0.4372441173701692 0.5944195873430834 0.552231510856533 1.0 0.8341687954742868 9 Q96T60,Q9BRJ7,O96028,Q5UIP0 4 +Positive regulation of stress fiber assembly 0.3952294368308633 0.5938027555141367 0.5526440458436197 1.0 0.8344136137448535 15 P09493 1 +Negative regulation of autophagy 0.3602949221615436 0.5916113851169391 0.5541108482271935 1.0 0.8349497727766759 26 O15118,Q08379,Q07820,Q9NWH9,P10619,Q14457,P31749 7 +Positive regulation of epithelial to mesenchymal transition 0.4923332694186119 0.5912584489067048 0.5543472654994379 1.0 0.8349497727766759 6 Q96AC1,Q15910,P35222 3 +Regulation of sister chromatid cohesion 0.4365224469655588 0.5912076118556854 0.5543813231890036 1.0 0.8349497727766759 9 Q8IY18,P23246 2 +Cellular response to inorganic substance 0.3222491749029092 0.589070110513654 0.5558142429237294 1.0 0.8359943295399458 45 O95831,P25705,Q14168,P05067,Q14457 5 +Biomineralization 0.3943234127560242 0.5888683748581558 0.5559495740369567 1.0 0.8359945862803525 15 O75116,O75844,Q6P4Q7 3 +Atrioventricular canal development 0.5053556715188043 0.5847781618522836 0.5586968901179394 1.0 0.8380453351769092 2 Q06124 1 +Organic hydroxy compound metabolic process 0.2926897304256014 0.5844989793040395 0.558884651775345 1.0 0.8381382927704532 129 P30837,O15118,Q8WTV0,O94788,Q96PE3,Q9UBM7,P05067,Q00796,P49748,P80404,Q15392,Q16850,Q9Y4G8,P48735,Q9NRA0,Q9H4L5,Q9NX62,P61916,Q9NWW5 19 +Central nervous system development 0.3068664624945998 0.5797832422930261 0.5620607996876674 1.0 0.8402653534277553 212 Q86XL3,P46379,P07942,P28370,O94788,Q15102,Q96N67,Q5KU26,Q8N3R9,P54802,O14773,O75503,Q9UQB8,P05067,P11166,Q06481,Q9BY67,P80404,O75787,Q14203,Q15375,O75592,Q92542,O15078,P50897,Q9Y4G8,O75530,P11274,Q9NRA0,Q9BRK5,Q96N66,P08670,O75569,Q9BSJ2,Q96RK4,O95456,P07196 37 +Toll like receptor 9 signaling pathway 0.5039824224114162 0.5794727206810022 0.5622702481799944 1.0 0.8402653534277553 2 P09429 1 +Positive regulation of toll like receptor 9 signaling pathway 0.5039824224114162 0.5794727206810022 0.5622702481799944 1.0 0.8402653534277553 2 P09429 1 +Regulation of toll like receptor 9 signaling pathway 0.5039824224114162 0.5794727206810022 0.5622702481799944 1.0 0.8402653534277553 2 P09429 1 +Cardiac epithelial to mesenchymal transition 0.5039824224114162 0.5794727206810022 0.5622702481799944 1.0 0.8402653534277553 2 Q53EL6 1 +Axonal fasciculation 0.503982422411416 0.5794727206810009 0.5622702481799953 1.0 0.8402653534277553 2 O14786 1 +Negative regulation of mitochondrial fusion 0.5603823635129014 0.5782962478714151 0.5630641272005423 1.0 0.8404480115020097 3 P02786 1 +Cellular response to endogenous stimulus 0.3209278237993581 0.5778737144462306 0.5633493829305507 1.0 0.8404829687564397 256 Q9BSK2,P42785,Q8WUH2,O15118,Q92896,Q9P1Z2,Q8N3R9,Q9UQB8,P05067,Q06481,O95831,O75116,O43865,Q92542,Q14457,O15173,P43490,Q16739,Q13464,Q01664,Q9Y4G8,Q9Y448,Q13573,P78536,Q7L576,P49354,P08670,Q99523,P25705,P31751,Q9NS86,O75844 32 +Mitotic metaphase plate congression 0.3376609170069958 0.5770378984984464 0.5639138541817736 1.0 0.841136783168381 33 Q96JM3,Q96DB5,Q9HD42,Q96EE3,Q8WXW3,Q9NZZ3,Q96EA4,Q9HC35,Q9Y6D9,Q14457,Q14807 11 +Protein localization to nucleolus 0.4156423308812157 0.5760279041605614 0.5645963207418181 1.0 0.8419662679280961 11 Q96D46,Q76FK4 2 +Smooth muscle contraction 0.415484520875055 0.5752736729258223 0.565106223845403 1.0 0.8421612099042541 11 O75116,P00813,Q13464 3 +Positive regulation of tumor necrosis factor mediated signaling pathway 0.4880443611337046 0.5748845702052425 0.5653693658997745 1.0 0.8422475447828109 6 Q13049 1 +Cell junction assembly 0.3057783555478259 0.5742211922422713 0.5658181303032008 1.0 0.8426567282544093 83 P12814,P35221,Q9BQT9,Q13464,O75116,Q9Y4G8,Q13641,Q15375,O75955,O00192,Q9BX67,P41440,P11274,P05067,Q16625 15 +Cellular response to alcohol 0.3633313559838155 0.5726721318817121 0.5668667099921116 1.0 0.8436512731401179 18 Q9NS86,O95831 2 +Eyelid development in camera type eye 0.5020598736610726 0.5720723475786397 0.5672729620269941 1.0 0.8436512731401179 2 Q92769 1 +Mitotic sister chromatid cohesion 0.3995070072338063 0.5718285413465559 0.5674381392157941 1.0 0.8436512731401179 14 Q8IY18,Q29RF7,Q12834 3 +Meiotic spindle organization 0.4594648290266372 0.5715520434886854 0.5676254926440265 1.0 0.8436512731401179 7 P35579,Q12768,Q08379 3 +Protein deneddylation 0.4175155029128842 0.5703753226233472 0.5684231632726628 1.0 0.8444600974104242 10 Q9UNS2,Q9BT78,P61201,Q9H9Q2 4 +O glycan processing 0.4860650359496529 0.5673712721769749 0.5704619634890256 1.0 0.846535917233302 6 Q10472,O43505 2 +Positive regulation of ion transport 0.3161556276495035 0.5672039354037134 0.5705756346153088 1.0 0.846535917233302 47 P55011,P33176,P22466,P80404,P14174,O43707,O95219,O43865,Q9NRA0,O14936 10 +Cilium movement 0.4136092021568994 0.5663276591916204 0.5711710612864969 1.0 0.846535917233302 11 Q9UPN4,Q00796 2 +Cellular response to steroid hormone stimulus 0.3094411249848032 0.5639779515086453 0.5727691375559651 1.0 0.8473127578592903 57 O15118,O15173,Q01664,O95831,P25705,Q9P1Z2,Q96HY6,Q9NUQ7,O94874 9 +Pyridine containing compound biosynthetic process 0.4574545046493644 0.5634863611497576 0.573103744798692 1.0 0.8473127578592903 7 P43490,Q9NVS9,O00764 3 +Negative regulation of leukocyte mediated immunity 0.4301105281486908 0.5628533977969639 0.5735347158861419 1.0 0.847629485409708 9 P11274,P30511,Q96FV9,P04439 4 +Protein localization to chromosome telomeric region 0.3805307472271443 0.561580024377343 0.5744021934771972 1.0 0.8482362178941856 16 Q9NVN8,P78371 2 +Negative regulation of protein localization to nucleus 0.4565456545654666 0.5598501673931627 0.5755816415445056 1.0 0.8484325893913288 7 P49841,P35221,Q9UHD1,Q96ST3,Q9BRK4,O95602 6 +Cell fate commitment 0.3608553166858716 0.5591561554851965 0.5760551528830369 1.0 0.8484325893913288 20 Q07820,P35222,Q96N67,Q92541,Q8N7H5 5 +Monovalent inorganic anion homeostasis 0.554689727715985 0.5588927138758805 0.5762349422950968 1.0 0.8484325893913288 3 P55011 1 +Negative regulation of neuron apoptotic process 0.3530285824441507 0.5580248913735412 0.5768273870997724 1.0 0.8484325893913288 27 Q01105,Q15233,P50897,P09601,Q13464,O76024,P48681,Q99538,P04062,P07196 10 +Biological process involved in interaction with host 0.3075223885056075 0.5579849014696314 0.5768546943142838 1.0 0.8484325893913288 61 Q14108,P19474,O15118,Q8WTV0,Q9BTY2 5 +Positive regulation of cell cycle process 0.3041372204414868 0.5578328184680658 0.5769585501698331 1.0 0.8484325893913288 82 Q96FV9,P06493,Q9Y6D9,P05067,Q8N7H5,Q8IY18,P12270,O75116,Q13769,Q96DY7,Q14457,Q7LG56,Q9UJX3,P31350,P78536,P31749,Q7L2J0,Q96HY6,Q9NYL9,P23246 20 +Myofibroblast differentiation 0.4982147761603861 0.5573690652490857 0.5772752966766994 1.0 0.8484325893913288 2 Q53EL6 1 +Interleukin 2 production 0.4288408781504403 0.557279413086168 0.5773365391415706 1.0 0.8484325893913288 9 Q01082,P14373 2 +Mapk cascade 0.3033430998888595 0.555809770949154 0.5783409052159505 1.0 0.8495338296855992 105 O15344,Q86VI3,Q13464,O75787,P14174,O75116,Q9Y4G8,P57105,Q13641,Q15375,Q9UMX5,P05067,P29372 13 +Nephron morphogenesis 0.5090527543559905 0.5553373413929118 0.5786639420329576 1.0 0.8496754164972247 5 P35222 1 +Iron sulfur cluster assembly 0.4078400511670925 0.5551093639714976 0.5788198582441697 1.0 0.8496754164972247 12 O75027 1 +Pattern recognition receptor signaling pathway 0.3308289052447266 0.553415891218976 0.5799786598099212 1.0 0.8506268567716277 34 Q9NPR9,P41440,Q06481 3 +Positive regulation of endocytosis 0.3575427383131501 0.5531668586799989 0.5801491583167897 1.0 0.8506896659033384 24 P41440,P50897,Q06481 3 +Smoothened signaling pathway 0.3565885879784389 0.5470059016426068 0.5843746775987966 1.0 0.8550091233595246 24 Q86SX3,Q9BZG1,Q9Y366,O43805,Q4G0X4,A0AVF1 6 +Cell adhesion mediated by integrin 0.4123255113760711 0.546367613716745 0.5848132675417939 1.0 0.855082466892906 10 P00813,P78536 2 +Sensory system development 0.3155086154228014 0.545244960207876 0.5855850530910813 1.0 0.8557266343179047 46 Q15555,O15078,P08670,O94788,P54802 5 +Mismatch repair 0.4057549984605364 0.5449795987411716 0.5857675490205558 1.0 0.8557266343179047 12 Q9UQ84 1 +Integrin activation 0.5493996906575772 0.5410588710516759 0.5884670056992092 1.0 0.8583528150117843 3 Q9BX67 1 +Regulation of endocytosis 0.3063728959653797 0.5391061933638179 0.589813582363901 1.0 0.8601286713264767 59 P50897,Q06481,Q13464,P30533,P57105,O00291,O75955,P41440,P05067 9 +Nucleoside triphosphate metabolic process 0.3071808220912952 0.5385090465444781 0.5902256612585361 1.0 0.8605412649815375 52 P55263,P00846,Q9H773,O75964,P00813,Q9NRA0 6 +Phosphatidylinositol 3 phosphate biosynthetic process 0.5042204704623254 0.5380322885515211 0.5905547574208438 1.0 0.8606444332228964 5 Q14457 1 +Regulation of actin filament organization 0.3006562374774232 0.5378297803927599 0.5906945701562716 1.0 0.8606599433525558 76 Q9NUQ9,Q96RK4,Q9Y5X1,Q13464,Q9NWH9,Q13136,O75116,P14373,Q96F07,Q01082,P09493,Q7L576,Q9UQB8,Q13813,Q9UEY8 15 +Positive regulation by host of viral transcription 0.4375321472106735 0.5365984002728472 0.5915450493781278 1.0 0.8613155924119767 8 Q13573 1 +Synaptic signaling 0.3029787777107947 0.536290677867462 0.5917576723193831 1.0 0.8613155924119767 99 Q4J6C6,Q9BQT9,Q7L0J3,Q12834,Q9UQB8,P05067,Q9NR77,P16615,P80404,Q92542,P33176,O14936,P55011,P50897,Q13641,Q9Y4G8,Q14168,Q7L576,P41440,P11274,P57105,O75955 22 +Nuclear pore organization 0.3999156281375676 0.5347722335824271 0.5928073655108232 1.0 0.862606568333395 13 Q9BTX1,Q96EE3,P12270,Q8N1F7,Q7Z3B4 5 +Centrosome separation 0.4769952846044951 0.5333111150070428 0.5938182347754368 1.0 0.863511763052976 6 P52732 1 +Negative regulation of cellular component organization 0.2974520554233703 0.5325568210912824 0.5943403986235913 1.0 0.8639741080021218 195 Q13045,O15344,Q9NVN8,Q13136,P02545,O14976,Q9Y6D9,Q96G23,P05067,Q13432,Q9NR77,O60313,Q8N0X7,P02786,O75116,Q15375,Q96DY7,Q13813,Q14457,P29372,Q9P2X3,Q13464,P45880,Q9Y4G8,Q96EA4,P30533,Q9BX67,Q9H300,Q9NUQ9,P08670,Q9NWH9,Q01082,Q96RK4,Q6ZVM7,Q9NQX7,Q9UEY8,Q9UIG0 37 +Protein import into peroxisome membrane 0.4916231804449256 0.5324772213516484 0.5943955141950663 1.0 0.8639741080021218 2 P40855 1 +Cilium organization 0.2990020832377053 0.5316322991573561 0.5949806898326948 1.0 0.8646360602737722 70 Q15051,Q15555,Q9Y496,O15078,Q8WXW3,Q96C92,A6NIH7,Q14203,Q96RK4,Q9Y366,O43805,Q9UPN4,Q9H223,A0AVF1 14 +Natural killer cell mediated immunity 0.3991603351109684 0.5310268528580316 0.595400171132735 1.0 0.8648468227684641 13 P51809,P30511,P33176,Q9BY67 4 +Mitochondrial translation 0.3060800892626039 0.5304803548131493 0.595778926176842 1.0 0.8648468227684641 50 P82912,P46199,Q9Y3D3,Q9BT17,P82914,Q9Y2R0,Q5JTZ9,Q567V2,Q9BRT2,Q96EL2,Q5JPH6,Q9NWS8 12 +Growth hormone receptor signaling pathway via jak stat 0.4910738808019677 0.5304213779771162 0.5958198071333525 1.0 0.8648468227684641 2 P40763 1 +Cellular response to growth hormone stimulus 0.4910738808019677 0.5304213779771162 0.5958198071333525 1.0 0.8648468227684641 2 P40763 1 +Protein k63 linked deubiquitination 0.4221585345927517 0.5281769373349255 0.5973765348958682 1.0 0.8659624577455514 9 O95630,Q9NZM5,P40818,Q93009 4 +Ectoderm development 0.5453172654870571 0.5274315652051451 0.5978939283217242 1.0 0.8664130588098408 3 P35222 1 +Regulation of receptor internalization 0.4051592344721829 0.526421451530045 0.5985954143603287 1.0 0.8668639960623494 11 P41440,O75955 2 +Homophilic cell adhesion via plasma membrane adhesion molecules 0.3980821708322497 0.5256906408966454 0.5991031675711844 1.0 0.8673597646365248 13 Q9BY67,Q9BQT9,Q14126,O60245,O15031,O75147,P35613,P19022 8 +Regulation of protein kinase activity 0.299703660679084 0.5255540233800351 0.5991981084529376 1.0 0.8673597646365248 109 P23396,Q14012,P54619,Q8WXW3,Q9Y5X1,Q01664,P14174,Q9Y4G8,P14373,P12956,O95684,P78536,P05067,Q8NDZ4 14 +Mrna 3 end processing 0.3219093066847325 0.5252407537501449 0.5994158375668741 1.0 0.8674864738723028 40 Q9UKF6,Q96MU7,Q05048,Q6PJT7,O75150,Q5KU26,Q92797,Q9H2U1,O43865,Q8N684,Q6PD62,P05067,Q8N7H5 13 +Gmp biosynthetic process 0.3977693994157424 0.5241449010185032 0.6001777605046759 1.0 0.8680325627270777 13 P00813 1 +Regulation of cell morphogenesis involved in differentiation 0.3372481566017934 0.5240858293876859 0.6002188441853344 1.0 0.8680325627270777 31 Q9UQB8 1 +Protein localization to chromosome 0.3112230623887695 0.5233078783466112 0.6007600193601781 1.0 0.8680325627270777 47 P78371,Q9NVN8,Q8IY18,Q96EA4,Q96DY7,Q9UFC0 6 +Pentose metabolic process 0.5000397463783791 0.5231995617863606 0.6008353863570888 1.0 0.8680325627270777 5 P11413 1 +Positive regulation of actin filament bundle assembly 0.3734388327355828 0.5221275631938735 0.6015815165015923 1.0 0.8684281721589074 16 P09493 1 +Positive regulation of leukocyte migration 0.3547692584911558 0.521674588867676 0.6018969203018196 1.0 0.8684281721589074 20 P78536,Q9BX67,P05067 3 +Sterol transport 0.3426692567072624 0.5215629926867977 0.6019746356207967 1.0 0.8684281721589074 29 Q8WTV0,Q9H4L5,O15118 3 +Regulation of protein polymerization 0.3004774483449212 0.5214148767000044 0.6020777902331544 1.0 0.8684281721589074 67 P23396,Q13045,Q9NUQ9,Q9Y5X1,Q9NWH9,Q14203,P45880,Q96F07,Q01082,Q96RK4,Q7L576,Q9UQB8,Q13813,Q9UEY8 14 +Lipid import into cell 0.4465486350943566 0.5202937302167566 0.6028588651683202 1.0 0.8684281721589074 7 P11166,P31751 2 +Regulation of transcription by glucose 0.4883273825871956 0.5201860284549472 0.6029339223183303 1.0 0.8684281721589074 2 O43159 1 +Mhc class ii biosynthetic process 0.4883273825871915 0.5201860284549319 0.602933922318341 1.0 0.8684281721589074 2 Q92769 1 +Protein polymerization 0.3019618703048032 0.5192449312732693 0.6035899499697202 1.0 0.8688883051286592 92 Q13045,Q16763,Q9UQB8,Q16625,Q96CW5,Q08379,Q14203,Q13813,Q13049,P23396,P45880,Q96F07,Q7L576,Q9NUQ9,Q9Y5X1,Q9NWH9,Q01082,Q9BSJ2,Q96RK4,P07196,Q9UEY8 21 +Positive regulation of isotype switching to igg isotypes 0.4880527327657139 0.519166555590924 0.6036445991956421 1.0 0.8688883051286592 2 P43246 1 +Positive regulation of potassium ion transport 0.4199867427513007 0.5188067064116717 0.6038955407545485 1.0 0.8690617684767941 9 P22466 1 +Cell junction maintenance 0.4197640633809358 0.5178484857765038 0.6045639862967191 1.0 0.8697610871111731 9 Q9BRK5,Q14203 2 +Peptide transport 0.3197814522122947 0.5176870455014875 0.6046766381566129 1.0 0.8697610871111731 41 Q13555,P53985,P22466 3 +Synapse assembly 0.3532310085621398 0.5167627169502128 0.6053218091681452 1.0 0.8701056746457954 22 Q13641,Q9BQT9,P05067 3 +Negative regulation of cell development 0.3442858757572131 0.5150737886734287 0.6065014581372008 1.0 0.8707370100349157 28 Q8N0X7,Q06481,O43707,Q9Y4G8,Q96G23 5 +Cytosolic calcium ion transport 0.3441768967843692 0.5143349359864995 0.6070178401881416 1.0 0.8710469298208848 28 P21796,Q9NWR8,P16615,Q9H4I9,Q8IYU8 5 +Positive regulation of transcription from rna polymerase ii promoter in response to stress 0.4866794836583291 0.5140804074132624 0.6071957749509953 1.0 0.8710469298208848 2 P04637 1 +Rna polymerase i preinitiation complex assembly 0.4715410432705869 0.5131351662958746 0.6078567738579403 1.0 0.8712239496710426 6 Q12824,Q9UIF9,P17480 3 +Transcription initiation from rna polymerase i promoter 0.4715410432705869 0.5131351662958746 0.6078567738579403 1.0 0.8712239496710426 6 Q12824,Q9UIF9,P17480 3 +Regulation of transmembrane transport 0.2996786168761124 0.5130985917045124 0.6078823565992311 1.0 0.8712239496710426 80 P21796,P22466,Q06481,O43707,P31751,O43865,Q9NRA0,O75844,P05067,P46939 10 +Negative regulation of chondrocyte differentiation 0.5407855803411361 0.5124479292488484 0.6083375541182465 1.0 0.8715014240141639 3 P35222 1 +Negative regulation of cartilage development 0.5407855803411361 0.5124479292488484 0.6083375541182465 1.0 0.8715014240141639 3 P35222 1 +Actin filament bundle organization 0.3039696040922787 0.5110464861844246 0.6093185063153996 1.0 0.8722073343474198 50 P12814,Q13464,Q13136,O75116,P09493,Q9UQB8 6 +Spindle organization 0.3010376288928549 0.5094216089085837 0.6104567329467812 1.0 0.8726969486913226 90 Q9HD42,Q8WVM7,Q9H6D7,Q12834,P35579,Q9UH99,Q96CW5,Q9H3R5,Q08379,Q14203,P23396,Q8WXW3,P52732,Q9Y448,Q9UQE7,Q15555,O94927,Q96CS2,O43663 19 +Response to axon injury 0.3795166146368967 0.5094206917383837 0.6104573756909368 1.0 0.8726969486913226 15 P07196,P10586 2 +Protein localization to cell periphery 0.3006344370107688 0.5065980938339361 0.6124368460887246 1.0 0.8746194977299333 98 Q9BZG1,Q4J6C6,P84095,Q8IWJ2,Q13464,Q13136,O75116,Q9Y4G8,Q9BXS4,Q13641,Q01082,Q8N3R9,O75955,P31751,O14976,P41440,P33176 17 +Male gamete generation 0.3005163644737061 0.5042590112285171 0.6140793769662405 1.0 0.8757728785800643 89 Q07666,P46379,P54619,Q15102,P14373,P11717,Q9BY67,O95714,Q00536,O75718,Q9Y2W6,Q96MU7,Q8N2A8,Q9BTX1,O15287,Q9BX67,Q96PU8,Q9BPZ3,Q9UJC3,Q9H2U1,Q96RK4,Q9UPN4,P26583,Q9P0K7,A0AVF1 25 +Post golgi vesicle mediated transport 0.3033761866643505 0.5040661070311447 0.6142149231446292 1.0 0.8757787359111201 51 Q92538,O15127,Q4J6C6,P42566,Q8IWJ2,Q8N2H4,Q99523,Q01082,O14976,Q9BZG1,O60826,Q567U6 12 +Positive regulation of neurogenesis 0.3124162884394609 0.5037783282323565 0.614417158464521 1.0 0.8758796591461497 45 Q9UQB8,P07196,Q13573 3 +Zymogen activation 0.4156910314221648 0.5004068555383578 0.616788627140723 1.0 0.8781330390253499 9 Q96F07,Q15392 2 +Endoplasmic reticulum calcium ion homeostasis 0.4019345931824007 0.4990733716625702 0.6177276959474267 1.0 0.8790405382504407 10 P05067 1 +Formation of translation preinitiation complex 0.4017067191021731 0.498048516976989 0.618449846196337 1.0 0.8795584472158364 10 P55010,Q15056 2 +Positive regulation of homotypic cell cell adhesion 0.4820104366932103 0.496929811177485 0.6192385482576146 1.0 0.8798495337805642 2 Q12955 1 +Type b pancreatic cell development 0.4670781863676196 0.496808376718093 0.619324187523107 1.0 0.8798495337805642 6 P19022,P31749 2 +Morphogenesis of embryonic epithelium 0.341449483444215 0.4959079397917627 0.6199593640977124 1.0 0.8799597837199219 28 O94788,Q8N3R9 2 +Regulation of actin filament based process 0.2996428838040157 0.4947292582348349 0.6207912456906859 1.0 0.8799597837199219 98 P84095,Q86VI3,Q13136,P14373,Q9UQB8,P35579,P16615,O75116,O75592,Q13813,Q13464,Q96F07,P09493,Q7L576,Q9BX67,Q9NUQ9,Q9Y5X1,Q9NWH9,Q01082,Q96RK4,Q9UEY8 21 +Regulation of protein localization to cilium 0.4919039958448252 0.4947236822140375 0.6207951822493669 1.0 0.8799597837199219 5 Q96C92 1 +Positive regulation of nuclease activity 0.4916431776784726 0.4938196040903393 0.6214335867970571 1.0 0.8803887715879897 5 P23396,P31749 2 +Central nervous system neuron differentiation 0.3495125325386553 0.4936630473700877 0.6215441665240737 1.0 0.8803887715879897 22 Q9Y4G8,Q8N3R9 2 +Lipid metabolic process 0.3298485167071046 0.4932926686134677 0.6218058078533035 1.0 0.8804260593913203 318 O00116,P54619,Q9HCL2,O15118,P07099,Q8WTV0,O94788,Q96PE3,P14174,O14773,Q9UBM7,Q8NCC3,P05067,Q8N8N7,Q96G23,P06280,P16278,Q99805,Q9HB40,Q9BXW7,Q9UKU0,P22466,Q06481,P49748,P53985,Q15392,Q14739,O14678,P35790,Q9Y6K0,Q8NHP8,O75592,P32929,Q14457,Q969N2,Q16850,Q8N2A8,P07602,P50897,P23786,Q8NBX0,Q8NBJ4,Q16739,Q9BWD1,O60512,O15254,Q9NRA0,Q9H4L5,Q96N66,P04066,Q9NX62,P61916,Q9NPH0,P25705,P15291,P31751,O43681,Q9NWW5,O75844 59 +Cellular lipid metabolic process 0.3099122678202671 0.492826280925637 0.6221353393879974 1.0 0.8804807451714678 237 O00116,P54619,Q9HCL2,P07099,Q8WTV0,O94788,Q96PE3,P14174,Q96G23,Q8NCC3,P06280,Q8N8N7,P16278,Q99805,Q9BXW7,Q9HB40,Q9UKU0,P49748,Q06481,O14678,P35790,Q9Y6K0,Q8NHP8,O75592,Q969N2,Q14457,P07602,P50897,P23786,Q8NBX0,Q16739,Q9BWD1,O60512,O15254,Q9NRA0,Q96N66,P04066,Q9NX62,P61916,Q9NPH0,P31751,Q9NWW5,O75844 43 +Substrate adhesion dependent cell spreading 0.3467590214513376 0.489728857414269 0.6243257787807206 1.0 0.8828273904957431 25 P07942,Q14185 2 +Regulation of protein lipidation 0.5149456695144625 0.4882806623557013 0.6253510567312897 1.0 0.8835271609415994 4 P04062 1 +Membrane fusion 0.3071194378575318 0.4872046034538761 0.6261133433715753 1.0 0.883594866597823 47 O60499,Q8WUH2,Q15075,P51809,Q99747,Q86Y82,O60343,P31751,O43752,Q9BZG1,O15400,Q969M3 12 +Nucleoside phosphate catabolic process 0.3488097102471765 0.4869027313373065 0.6263272632360075 1.0 0.883594866597823 21 P00813 1 +Regulation of lipoprotein metabolic process 0.4891424775519439 0.4851800284688185 0.6275486475926573 1.0 0.8844247677198751 5 P04062,Q15042 2 +Positive regulation of cytoplasmic translation 0.3987499224722716 0.4848010335745882 0.627817489491048 1.0 0.8844247677198751 10 Q9H2U1,Q9NZI8,O60506 3 +Golgi ribbon formation 0.4372300918294562 0.484201824768848 0.6282426419988296 1.0 0.8844865693830093 7 Q08379,Q8IWJ2 2 +Positive regulation of protein tyrosine kinase activity 0.4246151896485823 0.4841179380117272 0.6283021714407013 1.0 0.8844865693830093 8 P78536 1 +Walking behavior 0.48877102200807 0.4839011638434306 0.628456014368985 1.0 0.8844865693830093 5 O75844 1 +Pore complex assembly 0.3822735235115958 0.483491142384759 0.6287470475120187 1.0 0.8845546640512018 14 Q9BTX1,P12270,Q92621,P57740,Q8N1F7 5 +Positive regulation of cell cycle g1 s phase transition 0.3481043578108171 0.4826039939033886 0.6293769427465927 1.0 0.8850862324863966 21 Q8N7H5,P31350,Q96HY6,P78536,Q96DY7,P31749 6 +Actin filament based process 0.2938171459278647 0.4817236995921189 0.6300022379922221 1.0 0.885404959236907 194 Q13045,Q4VCS5,P84095,Q86VI3,Q13136,P14373,P06753,Q9UM22,O00291,Q9Y5S2,Q9UQB8,P46939,P35579,Q9UH99,Q96JJ3,Q7Z406,P16615,O75116,Q9H2J4,P67936,O75592,Q13049,Q13813,Q5VSL9,P12814,Q13464,O43707,Q96F07,P09493,Q7L576,Q9BX67,P11274,Q9NUQ9,P35580,Q9Y5X1,Q9NWH9,Q6WCQ1,Q5M775,Q01082,Q96RK4,Q9UEY8 41 +T cell differentiation in thymus 0.3890156000226632 0.4813175679412264 0.6302908129733278 1.0 0.8856237213920883 13 P00813 1 +Monocarboxylic acid biosynthetic process 0.308028383869008 0.4801524466298931 0.6311189975272242 1.0 0.8866004386514642 46 O94788,P14174 2 +Mitotic spindle assembly 0.3161964633153569 0.4791784584053941 0.6318116776833556 1.0 0.887107399344039 40 Q9UQE7,Q9HD42,Q08379,P12270,Q8WXW3,Q9NZZ3,Q8N3U4,Q8WVM7,P52732,O43663,Q12834,O95239 12 +Behavior 0.2972440785412236 0.4775570152758078 0.6329655312758915 1.0 0.8875594116977791 83 Q96RK4,P22466,P50897,O15118,P17655,Q7Z406,P53985,P80404,Q14203,P51790,Q13641,P10253,P54802,Q9NWW5,O75844,Q92542,P05067 17 +Positive regulation of protein localization to membrane 0.327616583164025 0.4774615506506234 0.6330334938281466 1.0 0.8875594116977791 32 P27105,P84095,Q01082,P31751,Q9GZY8,P33176 6 +Cell projection organization 0.3242169488359553 0.4773807986945667 0.6330909846516346 1.0 0.8875594116977791 294 Q92538,Q14012,P07942,Q14108,Q9Y496,P51114,P84095,Q96C92,Q96N67,O14976,Q12834,Q9Y366,Q9NY93,Q9UQB8,Q96G23,P05067,Q16625,Q9NR77,P35579,P35221,Q06481,Q8N0X7,A6NIH7,Q14203,Q15375,P42892,Q9BZG1,O43805,O75592,Q13049,P33176,Q9NZM3,O15078,Q9P2X3,Q96TA1,Q8WXW3,Q13464,Q13641,Q9Y4G8,Q96F07,P09493,Q7L576,P41440,Q9H223,Q15051,Q15555,Q96RK4,P08670,Q13555,Q9Y5Y2,Q8NCA5,Q9UPN4,Q9H2U1,O95684,O75955,P10586,Q99538,Q9NQX7,P07196,A0AVF1 60 +Viral gene expression 0.3091890568269696 0.4762466777184898 0.6338986486229352 1.0 0.8875594116977791 45 P19474,Q01664,O60858,P14373,Q13573,Q13049 6 +Response to iron ion 0.4099033428550593 0.4759113106112543 0.6341375638555364 1.0 0.8875594116977791 9 P09601,P02786,P80404,Q14457 4 +Positive regulation of cell death 0.2849729795941733 0.475304909398888 0.6345696603507966 1.0 0.8875594116977791 129 Q05639,Q15287,P98175,O94788,Q07820,O94813,Q9Y6C9,P11717,Q9NZI8,P35221,P22466,P09601,O95831,O95140,Q15375,Q9UHI6,Q02952,Q14457,P00403,P23396,Q13043,Q9NYF8,Q01664,O60858,Q9Y4G8,Q9Y5Z4,P52756,O00213,Q9NRA0,P35222,O75569,P17655,Q96A26,P15291,Q9NR28,Q9NQX7,P23246 37 +Positive regulation of proteolysis involved in cellular protein catabolic process 0.3057314157185745 0.4750858261849786 0.6347258006499867 1.0 0.8875594116977791 47 Q9Y4X5,P46379,Q6ZXV5,Q12834,Q96HY6,O60826 6 +Ventricular cardiac muscle tissue development 0.4348263091302004 0.4750228764646681 0.6347706678334202 1.0 0.8875594116977791 7 P09493 1 +Cell cell adhesion via plasma membrane adhesion molecules 0.3468405542436092 0.4749212437987173 0.6348431089768067 1.0 0.8875594116977791 21 Q13740,Q16539,Q9BY67,Q9BQT9,Q14126,O60245,O15031,O75147,P35613,P10586,O00192,P19022 12 +Regulation of carbohydrate catabolic process 0.3729302148326344 0.474889972027477 0.634865399392408 1.0 0.8875594116977791 15 Q14108,P05067 2 +Regulation of bicellular tight junction assembly 0.4345181587070608 0.4738502349005023 0.6356067089633317 1.0 0.8879998778942655 7 O75116 1 +Tube development 0.2768670803590416 0.4726766169377713 0.6364439114828633 1.0 0.8880891690492814 156 P35579,Q9Y366,P46379,P42785,O15078,Q96TA1,O94788,Q9NZ08,O75787,O75116,Q9Y4G8,P15291,P57105,O60476,P42892,Q9H2J4,P00813 17 +Muscle structure development 0.2965715752590946 0.4719113992328568 0.6369900311860333 1.0 0.8884790826444504 105 Q13045,Q14012,P51114,P02545,P46939,P35579,Q7Z406,P16615,P32929,Q13049,P12814,Q8IV08,Q96TA1,P61201,O43707,P09493,P41440,Q9Y5B6,Q96PU8,P17655,Q14331,Q99523,Q7Z4V5,O75955,O75844 25 +Receptor metabolic process 0.3169474516938347 0.4694377058672949 0.6387568020419061 1.0 0.8898646158662838 38 P49354,P02786,P30533,P42892,O75955,P41440,Q9NUN5,Q14457 8 +Regulation of fatty acid metabolic process 0.3461011311323728 0.4688677921173618 0.6391641393134655 1.0 0.8898646158662838 19 P49748,Q06481,Q8WXW3,Q92604,P31751,P31749 6 +Sulfur compound catabolic process 0.4328959113478824 0.4676922671415841 0.6400046718172161 1.0 0.8899606162311706 7 P16278 1 +Maintenance of protein localization in endoplasmic reticulum 0.508559998294485 0.4673162624333464 0.6402736230814066 1.0 0.8899606162311706 4 P24390,O15258 2 +Protein retention in er lumen 0.508559998294485 0.4673162624333464 0.6402736230814066 1.0 0.8899606162311706 4 P24390,O15258 2 +Steroid metabolic process 0.2949138274300568 0.4669817166175413 0.6405129590743077 1.0 0.8899606162311706 78 Q9H4L5,Q16850,P22466,O15118,Q8WTV0,Q15392,Q9NWW5,P05067 8 +Mammary gland epithelium development 0.4077466703236778 0.4668740507431168 0.6405899918122009 1.0 0.8899606162311706 9 Q86VI3,P31751 2 +Positive regulation of g1 s transition of mitotic cell cycle 0.3713496156004927 0.4666860442619533 0.6407245159002541 1.0 0.8899619448495713 15 P31350,Q96DY7,P31749,P78536 4 +Regulation of protein localization to chromosome telomeric region 0.3891283616592732 0.4658189884491457 0.6413450721592173 1.0 0.8900816946046376 12 P78371 1 +Negative regulation of cell junction assembly 0.4071202215763931 0.4642584973044116 0.6424625549635046 1.0 0.8907721542540703 9 O75116,Q13464 2 +Regulation of actomyosin structure organization 0.3342727998421997 0.4641092992103413 0.6425694396133665 1.0 0.8907721542540703 29 Q96RK4,Q9NWH9,Q13464,Q13136,O75116,P09493 6 +Transferrin transport 0.4829387124712092 0.4639764330674513 0.6426646303785724 1.0 0.8907721542540703 5 Q07960 1 +Neutral amino acid transport 0.4579115559308582 0.4638176374662749 0.6427784057712096 1.0 0.8907721542540703 6 Q15758,Q01650 2 +Oligosaccharide metabolic process 0.4314071637729905 0.4620640246354186 0.6440354078391772 1.0 0.8915869358887258 7 P15291,P06280 2 +Muscle cell migration 0.37790005722833 0.4616202943498586 0.6443536384985085 1.0 0.891822828831243 14 Q13464,P09493 2 +Regulation of trans synaptic signaling 0.2973666019460399 0.4608296626401366 0.6449208184595294 1.0 0.892256522715084 62 P41440,Q4J6C6,Q9BQT9,P16615,Q9Y4G8,Q14168,Q12834,O75955,Q7L576,Q9UQB8,Q92542,P05067,P33176 13 +Positive regulation of cell size 0.4718483932985385 0.4603964995994359 0.6452316467473458 1.0 0.89231599466118 2 P08238 1 +Positive regulation of arp2 3 complex mediated actin nucleation 0.5244024864231371 0.4596194539279791 0.6457893929840679 1.0 0.8927167480192624 3 Q7L576 1 +Regulation of neurotransmitter transport 0.361577414521549 0.4575354527525957 0.6472862259978678 1.0 0.8945402097052889 16 P41440,P16615,Q4J6C6 3 +Positive regulation of histone methylation 0.3422159249892548 0.4558333611471485 0.6485098122271686 1.0 0.895289133853772 24 Q9Y5B6,Q8N7H5,P02545,Q92541,Q13573,Q6PD62,P35222 7 +Regulation of neuroblast proliferation 0.4804070164717021 0.4554203613320297 0.6488068495712924 1.0 0.895289133853772 5 P35221 1 +Regulation of axon guidance 0.4803852607975704 0.4553470853906339 0.6488595568632545 1.0 0.895289133853772 5 O94813,O75592 2 +Histone h3 acetylation 0.3436567817650379 0.4551526325993946 0.6489994350352988 1.0 0.8952967361573904 18 Q9UPT9,Q9NRA0 2 +Regulation of protein localization to cell periphery 0.3172214852814574 0.4546014926195577 0.6493959607487523 1.0 0.8955609749911919 35 P84095,Q9BXS4,P33176,Q13136 4 +Positive regulation of muscle cell differentiation 0.3865876400392941 0.4539994920358537 0.649829192402315 1.0 0.8956996088077419 12 Q96TA1,P32929,Q13049 3 +Positive regulation of immunoglobulin production 0.3830326291843757 0.4525621224386913 0.6508640787466078 1.0 0.8961570697597393 13 O96028,P02786,Q96FZ2,Q9NQT5 4 +Centromeric sister chromatid cohesion 0.4795145335855626 0.4524178790606667 0.6509679692034429 1.0 0.8961570697597393 5 O60566 1 +Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.5220891550772937 0.4523390346394572 0.6510247593066938 1.0 0.8961570697597393 3 P23246 1 +Vesicle cytoskeletal trafficking 0.3605149657548931 0.4518437542520135 0.651381546449828 1.0 0.8963558950836853 16 P33176,Q9Y496,O43707 3 +Production of sirna involved in rna interference 0.5035807128189961 0.4512066000849135 0.6518406532154877 1.0 0.8966173146933928 4 O75569 1 +Negative regulation of oxidoreductase activity 0.502597635218721 0.4480513738300985 0.6541161204519179 1.0 0.898293263011818 4 P06280 1 +Negative regulation of meiotic cell cycle 0.4680032957978522 0.4468711662812752 0.6549680837066623 1.0 0.898507791175122 2 P33981 1 +Female meiosis i 0.4680032957978474 0.4468711662812592 0.6549680837066738 1.0 0.898507791175122 2 O14965 1 +Proteolysis 0.3350214086644589 0.4462252833068535 0.655434521334112 1.0 0.8987775706213599 435 P46379,P42785,O75503,P05067,P55786,Q9HB40,P19474,Q06481,Q9UIQ6,P28074,Q15392,O95831,Q9BXS4,P42892,P10619,P49721,O60858,Q4G0X4,P52888,Q9UNS2,Q9Y5X1,Q16740,Q99436,Q9UPT9,Q4J6C6,Q92896,P20618,P28072,Q8TCT8,P28070,Q13049,O75976,O15484,P78536,Q8IXB1,Q9NZ08,Q96A26,Q9NWW5,O60826,O75844,Q9HD42,Q12834,Q9Y366,Q8IVV7,P60900,P35579,O00231,O75787,O75116,Q9H2J4,Q92542,P22695,O95155,Q13464,Q01664,Q96F07,Q9H9S5,Q9BXK5,Q969M3,Q9H3G5,Q9BT78,Q96HY6,Q9NQH7,Q9H9Q2,O14773,O00291,Q9UHG3,Q9Y4X5,P02786,Q15375,Q6ZXV5,P23396,P48729,P61201,Q9H300,Q96K76,P17655,Q93009,Q96KC8,Q99538 80 +Sister chromatid cohesion 0.3353914584096267 0.4411988179780685 0.6590690688706373 1.0 0.9017915956322522 27 Q9UQE7,P23246,O60566,Q8IY18,Q8N3U4,Q8WVM7,P35222,Q12834,Q29RF7,Q14683,Q9NTI5 11 +Myeloid dendritic cell activation 0.4663553968689817 0.4411266967927517 0.6591212773118813 1.0 0.9017915956322522 2 P09429 1 +Left right axis specification 0.4663553968689816 0.441126696792751 0.6591212773118817 1.0 0.9017915956322522 2 Q9HCM4 1 +Left right pattern formation 0.4663553968689816 0.441126696792751 0.6591212773118817 1.0 0.9017915956322522 2 Q9HCM4 1 +Vesicle fusion to plasma membrane 0.5181318681318697 0.4399931258105958 0.6599420860962599 1.0 0.9023587358217484 3 O95721,Q5SQN1 2 +Dsrna processing 0.3410046701026238 0.4397473803261523 0.6601200822798974 1.0 0.9024169282377834 18 Q5TAX3,O75569,Q6ZN17,Q99598,P55265,O75844,Q8WYQ5 7 +Sodium ion transport 0.3385951603516716 0.4380987792135881 0.6613146793380604 1.0 0.9034227170582269 25 P27105,P55011,O43707,Q6P4Q7,O43865,Q9Y6M7,P46939 7 +Negative regulation of protein binding 0.330393423908586 0.4380092121851463 0.6613796054745227 1.0 0.9034227170582269 29 Q14012,Q9NVN8,Q08379,P16615,Q13464,Q92797,P10586 7 +Leukocyte chemotaxis 0.3249729837583655 0.4373765378730868 0.6618382965210914 1.0 0.9034227170582269 31 P55011,Q99538,P14174,P78536,Q9BX67 5 +Positive regulation of cell development 0.2928648533411442 0.4359674540919821 0.6628603430897095 1.0 0.9034227170582269 66 Q96TA1,Q13573,Q9UQB8,Q13049,P07196,Q14185 6 +Positive regulation of dna damage response signal transduction by p53 class mediator 0.5167582417582433 0.4357402119168097 0.6630252268369696 1.0 0.9034227170582269 3 P17844,O43324 2 +Negative regulation of innate immune response 0.357129529682789 0.4338187032956495 0.6644200986934663 1.0 0.9042030263320232 16 P19474 1 +Transmembrane receptor protein tyrosine kinase signaling pathway 0.2929270343478917 0.432213785959387 0.6655860406159173 1.0 0.9044803253417149 82 P11717,P43490,Q96TA1,Q9NWH9,Q99523,Q9Y4G8,Q96F07,P31751,O00291,P78536,Q7L576,Q9UQB8 12 +Cellular response to peptide hormone stimulus 0.2918487277411476 0.4319875472466558 0.6657504638576066 1.0 0.9044803253417149 67 Q9BSK2,Q06481,P43490,Q13464,O75116,O43865,Q7L576,Q9UQB8 8 +Response to alcohol 0.3079552138856195 0.4315856558561033 0.6660425856132091 1.0 0.9044803253417149 42 P16278,Q9BRK5,O95831,Q9NS86,P07196,Q9NRA0 6 +Xenobiotic metabolic process 0.3560583611952618 0.428151662917863 0.6685407055425396 1.0 0.9052447259595248 16 Q6N069,P07099 2 +Endocytic recycling 0.3288549101119528 0.4277426562026433 0.6688384902688473 1.0 0.9052447259595248 29 Q96C92,Q07960,O43752,O95219,O60826,Q9H223,Q567U6 7 +Nitrogen compound transport 0.2731721302341012 0.427461726699494 0.6690430562535432 1.0 0.9053277586956456 674 Q92538,P46379,O96008,Q07820,Q15629,O43772,Q7L0J3,Q99442,O75027,Q9BRT2,Q9H7Z3,Q9HC21,P55786,Q13432,A2RRP1,P20645,P22466,Q06481,P51991,Q00536,P53985,Q8IUD2,A6NIH7,O95831,Q8TB61,Q96GC9,Q96L92,P30825,O43865,P10619,P24390,O00410,Q16850,P27105,P07602,P50897,Q96JB2,Q9Y678,P61020,O15400,P41440,O60749,O60725,P31749,P49792,P60604,Q13555,Q9H814,Q9Y5X1,O15260,Q15437,Q99523,Q9UJC3,O43681,Q9GZY8,Q07666,Q8WUH2,Q96FV9,Q4J6C6,Q96EE3,Q8N2H4,Q01650,Q99595,Q9HCU5,Q9UHB9,Q9Y619,Q9Y666,Q5THJ4,O95563,O00400,O60518,O95714,P12270,P42566,Q9C0E2,O14678,Q10713,Q96ED9,Q9HD20,Q15758,Q13769,Q7Z3B4,O75592,Q96KP1,Q96D46,Q96MU7,Q9Y282,O60499,O15127,O15078,O15173,Q9H2D1,P55735,Q9NZZ3,Q9UBV2,Q14168,Q6P4A7,O95070,O00213,Q567U6,P35580,P57105,O95219,O75955,O60826,Q9BSK2,Q86VD7,Q14108,Q9HD42,Q96H78,Q96C92,Q8TD16,P02545,P35579,Q86UP2,Q07960,Q9Y6M1,P33176,O43707,Q8N1F7,P11274,Q969M3,Q01082,P31751,Q6ZVM7,Q9UPN4,A0AVF1,Q14012,Q9Y496,Q9P2E9,O75298,O00291,Q9Y5X2,Q08379,P02786,Q7Z434,P49321,P80404,Q15070,Q9BZG1,P55011,Q9BTX1,Q8IWJ2,O43752,O14523,Q9NPF0,Q9H300,Q96PU8,P51809,P35606,Q86YV9,Q969Q5,Q96KC8,Q96RK4 154 +Cerebral cortex cell migration 0.3854320063877757 0.4263740775115852 0.6698352873180009 1.0 0.9060504224464576 10 Q96N66,P07942,P35222,O94813 4 +Inorganic ion transmembrane transport 0.2775616013103184 0.4263551541409973 0.6698490741364627 1.0 0.9060504224464576 134 Q9HC07,O75027,Q7KZN9,P46939,Q9UHG3,P21796,Q8N4V1,Q9UBX3,P22466,Q9NWR8,P16615,O75251,Q6P4Q7,Q9HD20,Q9BPX6,P55011,P00846,O43707,P51790,O75964,Q9NRA0,Q9Y6M7,Q13423,Q9H4I9,P25705,Q8IYU8 26 +Cardiac ventricle development 0.3634125517369185 0.4260107550119831 0.6701000091339606 1.0 0.9062058779905784 15 O96028,P09493 2 +Regulation of dendritic cell differentiation 0.5124241617395203 0.4224335846048914 0.6727085684539749 1.0 0.908258802757616 3 P09429 1 +Purine nucleoside monophosphate biosynthetic process 0.3546117278090527 0.4205265654176218 0.6741008268638897 1.0 0.9082745746302172 16 P00813 1 +Neuroblast proliferation 0.3762477403218049 0.4205071315726453 0.674115020696824 1.0 0.9082745746302172 13 Q96N67,Q9NXR1,P35221 3 +Glucosylceramide metabolic process 0.5117643171732535 0.4204228645388678 0.6741765678728098 1.0 0.9082745746302172 3 Q16739 1 +Positive regulation of focal adhesion assembly 0.4081392072842956 0.4196293277700271 0.6747562602284212 1.0 0.9082745746302172 8 Q96AC1,Q13464,Q9HCM4 3 +Positive regulation of transcription by rna polymerase iii 0.3961469022238798 0.4191703686655383 0.6750916259467616 1.0 0.9082745746302172 9 Q9NY93,O75533,O60264,Q9UIG0 4 +Metaphase plate congression 0.3118648605185882 0.4190577314360386 0.6751739408890087 1.0 0.9082745746302172 36 Q96DB5,Q9HD42,Q96EE3,Q8WXW3,Q9NZZ3,Q96EA4,Q9HC35,Q9Y6D9,Q14457,Q14807 10 +Defense response to other organism 0.281013526169114 0.418581898636867 0.6755217209081952 1.0 0.9085589879715996 173 Q9HCL2,P30511,P14174,Q5KU26,P14373,Q9NY93,P19474,Q06481,Q9BY67,Q13049,Q14457,P33176,O60858,P12956,P78536,O00584,P08670,Q9NZ08,O75844,P23246 20 +Negative regulation of lipid metabolic process 0.3618073654499447 0.4178956136909187 0.6760234396649412 1.0 0.9090502882921296 15 Q8WXW3,P49748,Q06481 3 +Tor signaling 0.336424306211012 0.4166076054419792 0.6769654454808169 1.0 0.909944791003924 23 P55735,Q8NHS3 2 +Cellular component assembly involved in morphogenesis 0.3350280865492494 0.4159205862381804 0.677468115021445 1.0 0.910210817293022 25 Q9NR77,Q8N3R9 2 +Receptor internalization 0.3362598932812743 0.4156151969124798 0.6776916045620158 1.0 0.910210817293022 23 P02786,P41440,Q9NUN5,O75955 4 +Hepaticobiliary system development 0.3081173251344445 0.4153353199255496 0.6778964486152503 1.0 0.910210817293022 40 P11717,Q9BY67,O94788,P00813,O75844 5 +Regulation of small gtpase mediated signal transduction 0.3018682809194254 0.4147809175149622 0.6783022901649558 1.0 0.9102755353732556 45 Q92538,Q9NUQ9,Q15555,P41440,Q07960,Q9NWH9,O75955,Q92888,P11274 9 +Blastocyst growth 0.3949811099752345 0.414464744265133 0.6785337816104327 1.0 0.9102755353732556 9 Q6PD62,Q92541,Q9BRT9,P61201 4 +Anatomical structure formation involved in morphogenesis 0.286242767907237 0.4143305269106475 0.6786320602279514 1.0 0.9102755353732556 186 Q13045,P07942,Q14012,P42785,O94788,Q8N3R9,Q9Y366,Q9NR77,P35579,O75116,Q6P4Q7,Q9H2J4,P00813,P12814,P55011,O15078,Q96TA1,Q13464,P09493,P78536,Q9BX67,P41440,Q96N66,P17655,Q9NZ08,P15291,P57105,Q92541,O75955,Q96RK4 30 +Inositol lipid mediated signaling 0.3451607471847197 0.4137907804211788 0.6790273365580632 1.0 0.9102755353732556 17 Q10713,O95630,P42356,Q8NDZ4,Q9NZM5,O00443,Q14457,P31749 8 +Peripheral nervous system axon regeneration 0.4916813370733009 0.4136002063434338 0.679166922103746 1.0 0.9102755353732556 4 P07196 1 +Positive regulation of bmp signaling pathway 0.4434973879571134 0.4135473269331318 0.679205655456645 1.0 0.9102755353732556 6 Q14980,Q9C0C9,Q14318,Q04721,Q9BRX2 5 +Neural tube development 0.3266929209614475 0.4134002180578024 0.6793134148957953 1.0 0.9102755353732556 29 Q9Y366,O94788 2 +Respiratory gaseous exchange by respiratory system 0.3775443111636473 0.4125974065257125 0.6799016017032871 1.0 0.9102755353732556 12 O60476,P10253 2 +Multi multicellular organism process 0.3152967101819356 0.4120861010715487 0.6802763156576854 1.0 0.9102755353732556 33 P41440,Q9UIQ6,P15291,O75592,Q9NRA0 5 +Golgi to endosome transport 0.3819741400469434 0.4115618190802701 0.6806606215544653 1.0 0.9102755353732556 10 Q92538,Q99523,Q8N2H4 3 +Postsynaptic actin cytoskeleton organization 0.4900607706182296 0.4085802173182242 0.6828477508924546 1.0 0.9113297247235108 4 Q16352 1 +Positive regulation of torc1 signaling 0.5078183203095004 0.4084835716554104 0.682918689216357 1.0 0.9113297247235108 3 Q96EE3 1 +Mitochondrial atp synthesis coupled proton transport 0.3734298560850989 0.4073785475458178 0.6837299805056369 1.0 0.9113297247235108 13 P00846,O75964 2 +Epithelial cell morphogenesis 0.4165691169988662 0.4072378193388092 0.6838333271780963 1.0 0.9113297247235108 7 Q13464 1 +Localization within membrane 0.2973046581209018 0.4065803090738455 0.6843162619105856 1.0 0.9113297247235108 216 P46379,O15118,Q4J6C6,P84095,Q96C92,Q15629,Q9HD45,Q13136,Q99442,Q8N3R9,O14976,Q99805,Q8N4V1,Q07960,Q96L92,O75116,Q9BXS4,Q15070,Q9HD20,Q9BZG1,O43805,P33176,P27105,P07602,Q9BTX1,Q8IWJ2,Q13464,Q13641,Q9Y4G8,Q14168,O43752,O15400,P41440,Q9H223,O60725,Q567U6,P49354,Q86YV9,Q01082,P57105,P31751,O95219,O43681,O75955,O60826,Q9GZY8 46 +Negative regulation of protein import into nucleus 0.4559187036528364 0.405499401198566 0.685110458494161 1.0 0.9113297247235108 2 Q9UHD1 1 +Regulation of alternative mrna splicing via spliceosome 0.3173930506544223 0.4050202121176511 0.6854626538973898 1.0 0.9113297247235108 32 Q96MU7,Q07666,Q9UNW9,Q06787,Q15287,Q9UHX1,P98175,P51114,P52756,P51116,P49756,Q9Y2W1 12 +Negative regulation of helicase activity 0.4885957680681678 0.404063791554678 0.6861658102224499 1.0 0.9113297247235108 4 P33993,P49736,P04637 3 +Cellular component maintenance 0.378090393230311 0.4038115389677094 0.68635131056732 1.0 0.9113297247235108 11 Q9BRK5,Q14203 2 +Cellular response to sodium arsenite 0.4553694040098823 0.4036614468508048 0.6864616935839372 1.0 0.9113297247235108 2 P09651 1 +Cellular response to salt 0.4553694040098823 0.4036614468508048 0.6864616935839372 1.0 0.9113297247235108 2 P09651 1 +Erad pathway 0.2939450739280652 0.4036394898985347 0.6864778420589461 1.0 0.9113297247235108 49 O60858,Q8IXB1,P46379 3 +Bile acid metabolic process 0.3725039602968016 0.4030893881034833 0.6868824669910658 1.0 0.9113297247235108 13 Q9H4L5,O15118 2 +Negative regulation of nervous system development 0.3342201970037214 0.4010451645194522 0.6883868720433355 1.0 0.9120544299910012 22 Q9Y4G8,Q8N0X7,Q96G23,Q06481 4 +Positive regulation of catalytic activity 0.3003085859839489 0.3988563889958422 0.6899990248512435 1.0 0.9136453701478212 226 Q14012,P54619,P78371,Q8WTV0,P84095,Q96N67,P14174,P40938,Q12834,O00291,P05067,O95831,O75116,Q15375,Q92564,Q92542,Q8NDZ4,P23396,P20585,P07602,Q13464,Q01664,Q9Y4G8,Q96F07,P12956,Q9BXK5,Q9BRT9,P78536,P11274,Q15555,P49354,Q9Y5X1,Q9NWH9,Q96A26,P31751,Q96HY6 36 +Clathrin coat assembly 0.3788567239210859 0.3983435613126831 0.6903769543082436 1.0 0.9139641658167748 10 O00443,P42566,O00291 3 +Positive regulation of tor signaling 0.402367841329853 0.397767684783644 0.6908014397773758 1.0 0.9141556794337032 8 Q96EE3,P55735,Q15382 3 +Inositol phosphate metabolic process 0.4132612720967048 0.3953485780295455 0.6925856531459518 1.0 0.9148734215635552 7 Q96PE3,Q9NX62 2 +Positive regulation of amino acid transport 0.4618731444349662 0.394619970848795 0.6931233726628885 1.0 0.9148734215635552 5 P55011,P80404 2 +Positive regulation of amine transport 0.4618731444349662 0.394619970848795 0.6931233726628885 1.0 0.9148734215635552 5 P55011,P80404 2 +Skeletal muscle organ development 0.3320011236889267 0.393190057368772 0.6941791126538339 1.0 0.9153924039840936 24 P51114,Q96TA1,Q7Z406,P61201,O75955,P41440 6 +Regulation of autophagy of mitochondrion 0.3568646904935215 0.3931570571773524 0.6942034845162277 1.0 0.9153924039840936 15 P21796,Q9H300,P27544 3 +Vesicle cargo loading 0.3631692124488026 0.3898665953276473 0.6966351962950934 1.0 0.9169076371599484 14 Q15437 1 +Regulation of actin filament length 0.297242488766707 0.3888190449416707 0.6974100114139485 1.0 0.9169076371599484 46 Q9NUQ9,Q9Y5X1,Q96F07,Q01082,Q96RK4,Q7L576,Q9UQB8,Q13813,Q9UEY8 9 +Positive regulation of tau protein kinase activity 0.5010989010989029 0.3884967773828674 0.6976484384383612 1.0 0.9169076371599484 3 P10909,P08238 2 +Regulation of tau protein kinase activity 0.5010989010989029 0.3884967773828674 0.6976484384383612 1.0 0.9169076371599484 3 P10909,P08238 2 +Negative regulation of i kappab kinase nf kappab signaling 0.4359393957688338 0.3880426757856598 0.6979844524650431 1.0 0.9169076371599484 6 O60826 1 +Very low density lipoprotein particle assembly 0.5005494505494523 0.386882056202006 0.6988435258271934 1.0 0.9175161404111508 3 P35610,O95573 2 +Cardiac chamber development 0.3319066537367673 0.3862071277572246 0.6993432753147291 1.0 0.9176298234387632 21 O96028,P09493 2 +Regulation of stem cell population maintenance 0.4825611721095393 0.3856812403972109 0.6997327579282153 1.0 0.9178734499586718 4 O75175 1 +L serine catabolic process 0.4498764075803242 0.3854939649025412 0.6998714769571315 1.0 0.9178734499586718 2 P34897 1 +Regulation of water loss via skin 0.4350512963730757 0.3850866767431552 0.7001731987173911 1.0 0.9179956755320696 6 Q16739,Q9NWH9 2 +Regulation of macroautophagy 0.2880746350644839 0.3824661744798724 0.7021156140857276 1.0 0.9196375735508556 65 P21796,Q9Y487,O60858,Q93050,O95219,Q14457 6 +Muscle organ development 0.3062352747837694 0.3819932320098765 0.7024663847457118 1.0 0.91991617955202 37 Q9Y5B6,P51114,Q96TA1,Q7Z406,P61201,Q14331,O75955,P09493,P41440,P46939 10 +Circadian rhythm 0.2947242125479705 0.3808696731073713 0.7032999567979448 1.0 0.9204025013330882 47 Q15233,Q9Y2K7,P43490,O75116,Q93009,P54802,O75592,P23246 8 +Mitochondrial dna repair 0.4983516483516501 0.3804533768893449 0.7036088989694966 1.0 0.9204025013330882 3 P49916,P04637 2 +Receptor localization to synapse 0.370284084394146 0.3801695300072462 0.7038195757659811 1.0 0.9204025013330882 12 Q14168,P57105 2 +Actin filament polymerization 0.2946047101807998 0.379866925905136 0.7040441995821372 1.0 0.9204025013330882 47 Q9NUQ9,Q9Y5X1,Q96F07,Q01082,Q96RK4,Q7L576,Q9UQB8,Q13813,Q9UEY8 9 +Cyclic nucleotide metabolic process 0.4479538588299855 0.3792280073001144 0.7045185553288447 1.0 0.9204025013330882 2 Q01433 1 +Inflammatory response to antigenic stimulus 0.386007634858911 0.3788258022799219 0.7048172255135539 1.0 0.9204025013330882 9 P28070,Q15046 2 +Positive regulation of dna recombination 0.3255963025673791 0.3788128308879537 0.7048268585927469 1.0 0.9204025013330882 27 P02786,P35637,Q9NQT5,Q96FZ2,Q7Z4V5,O96028,Q9UBU8 7 +Platelet aggregation 0.3671915477709099 0.3787234447064251 0.7048932416656062 1.0 0.9204025013330882 13 P35579,P12814 2 +Regulation of nucleotide metabolic process 0.3303893949590609 0.3778546588171117 0.705538566638934 1.0 0.920682230614026 19 Q9NRA0,P05067 2 +Positive regulation of cell migration involved in sprouting angiogenesis 0.4793841681432659 0.3761499103920623 0.7068054511310444 1.0 0.9216353208448512 4 P09601 1 +Regulation of cell migration involved in sprouting angiogenesis 0.4793841681432659 0.3761499103920623 0.7068054511310444 1.0 0.9216353208448512 4 P09601 1 +Activation of gtpase activity 0.3298642952065687 0.374222486338968 0.7082387957340239 1.0 0.9225796864077812 20 Q8TC07,P84095,Q96N67,Q4KMP7,P31751,P11274 6 +Negative regulation of cellular response to growth factor stimulus 0.3686821669500345 0.3731183462965819 0.709060364697685 1.0 0.9227166084110808 12 Q96TA1,O14936,Q9Y2U8,Q8N0X7 4 +Lysosomal protein catabolic process 0.3957152878678312 0.3730791803693049 0.7090895135188131 1.0 0.9227166084110808 8 Q8NHS3 1 +Protein catabolic process in the vacuole 0.3957152878678312 0.3730791803693049 0.7090895135188131 1.0 0.9227166084110808 8 Q8NHS3 1 +Positive regulation of chromosome condensation 0.4535825397339528 0.3685461846843343 0.7124660143162111 1.0 0.9248316877827616 5 O95347,Q15021,Q9NTJ3 3 +Mitochondrion localization 0.3281910842153044 0.3670650314566885 0.7135705102671106 1.0 0.9255763161982448 18 O75153 1 +Atp synthesis coupled proton transport 0.3580681754338869 0.3657785680247413 0.7145303135279779 1.0 0.9261909331828108 14 P00846,O75964 2 +Mitotic cytokinesis 0.3024714920838978 0.3650710870875256 0.715058342768673 1.0 0.9261909331828108 39 Q13432,P35580,Q9HD42,Q9Y5X1,Q13464,O75116,Q01082,Q96RK4,Q6DKK2 9 +Secondary metabolic process 0.38222998044519 0.3641441548438955 0.7157503661398905 1.0 0.9267204735946089 9 Q9Y4G8 1 +Hindlimb morphogenesis 0.4750758343851753 0.363390414539546 0.7163132611866065 1.0 0.9267204735946089 4 P35222 1 +Embryonic hindlimb morphogenesis 0.4750758343851753 0.363390414539546 0.7163132611866065 1.0 0.9267204735946089 4 P35222 1 +Activation of cysteine type endopeptidase activity involved in apoptotic process 0.3507251176686015 0.3629807258895637 0.7166192823445006 1.0 0.9267204735946089 15 Q9BXK5,Q96A26,O95831 3 +Regulation of mononuclear cell migration 0.3278418512584316 0.3627445004368775 0.7167957540693386 1.0 0.9267204735946089 20 P78536,Q99538,P05067,P26038 4 +Microtubule organizing center localization 0.3573637915439632 0.3624855421060164 0.7169892257177994 1.0 0.9267204735946089 14 Q9NXR1,Q8TD16,Q9UH99,P33176 4 +Cochlea morphogenesis 0.4427355122219082 0.3624690484297752 0.7170015490057535 1.0 0.9267204735946089 2 O14641 1 +Planar cell polarity pathway involved in neural tube closure 0.4427355122219082 0.3624690484297752 0.7170015490057535 1.0 0.9267204735946089 2 O14641 1 +Animal organ morphogenesis 0.2859821753392301 0.3623104762991379 0.7171200302947325 1.0 0.9267204735946089 111 Q9Y366,P07942,Q15555,O15078,Q9NX62,Q92896,O94788,O75844,Q6P4Q7,P10253,P54802,P09493,O96028,O75592,P11274 15 +Protein transmembrane transport 0.3137916053606854 0.3612266271975353 0.7179300384610128 1.0 0.927587327179703 31 O96008,Q07820,Q15629,O95831,P31751,O75298,P11274 7 +Regulation of neutrophil chemotaxis 0.392294277224103 0.3606062382069827 0.7183938252699442 1.0 0.9278296249184662 8 O94813,Q8NHP6,P63000,Q00013,Q9BX67 5 +Negative regulation of protein kinase activity by regulation of protein phosphorylation 0.4510089218738695 0.3606032317353848 0.718396073083351 1.0 0.9278296249184662 5 P55265,Q96JB5 2 +Positive regulation of signal transduction by p53 class mediator 0.3678414096916354 0.3598714971983893 0.7189432329072469 1.0 0.9283563490040672 11 P62841,P61927,P61254,Q96JB5,O43324,P17844,P62081,P60866,O94992,P63241 10 +Skeletal system development 0.2875080135318389 0.3592905547026725 0.7193777395162932 1.0 0.928557512281492 52 Q9NX62,Q92896,O75569,Q7RTS9,O96028,O75844 6 +Ubiquitin recycling 0.45009552441594 0.3578018607119101 0.7204915979951192 1.0 0.9296241702382384 5 Q13049 1 +Atp biosynthetic process 0.3262981428349725 0.3564985881203451 0.7214672092498589 1.0 0.9296241702382384 23 P00846,Q9NRA0,O75964 3 +Sulfur compound transport 0.3622356005866952 0.3563821802256304 0.721554372616048 1.0 0.9296241702382384 13 Q9HC21,Q70HW3,Q9UBX3,Q8TB61 4 +Negative regulation of myeloid leukocyte mediated immunity 0.4899460745641843 0.35632216641655 0.7215993108918157 1.0 0.9296241702382384 3 P11274 1 +T cell activation involved in immune response 0.4020349803341784 0.3559807524484459 0.7218549795841629 1.0 0.9297737732397598 7 P42345,P40763,P62753,P09429,P17931 5 +Ribosomal small subunit export from nucleus 0.3900962861072956 0.3526750055716345 0.7243320994922948 1.0 0.9309644687230896 8 P62841,O14980,P06748,Q99567,Q9BVS4,Q96GA3,P62826 7 +Stress fiber assembly 0.3096981254782399 0.3521439073768453 0.7247303412900958 1.0 0.9309644687230896 32 Q96RK4,Q9NWH9,Q13464,Q13136,O75116,P09493 6 +Stress induced premature senescence 0.4884615384615403 0.3521370157736505 0.7247355094201802 1.0 0.9309644687230896 3 Q16539,P04637 2 +Negative regulation of camp dependent protein kinase activity 0.48846153846154 0.3521370157736493 0.7247355094201811 1.0 0.9309644687230896 3 P10644,P13861 2 +Single strand break repair 0.48846153846154 0.3521370157736493 0.7247355094201811 1.0 0.9309644687230896 3 P09874,P18887 2 +Muscle cell development 0.3034676959584457 0.3510179581787688 0.725574875897729 1.0 0.9312732152294008 34 Q13045,P12814,Q96TA1,P16615,Q16527,O43707,P02545,Q9Y4W6,P09493,Q9NYL9,O75844 11 +Positive regulation of defense response to virus by host 0.4245222303819479 0.3507279204820355 0.7257924770124511 1.0 0.9312732152294008 6 Q7Z434 1 +Negative regulation of response to wounding 0.3672973358651138 0.350524086843495 0.7259454166797754 1.0 0.9312732152294008 10 Q96G23,P80404,O14936 3 +Anatomical structure homeostasis 0.2976889076835507 0.3505123320617418 0.7259542368154746 1.0 0.9312732152294008 42 P11166,Q15051,P55011,Q15555,P02786,Q14203,P51790,P10253,O14773,Q96RK4,Q9BX67,Q13049 12 +Cellular modified amino acid catabolic process 0.4240075604630019 0.3490818258054774 0.7270278802907695 1.0 0.9317311323148352 6 Q9UHG3,Q8NBM8,Q9NRN7 3 +Telencephalon glial cell migration 0.3888394866879404 0.3481695464664727 0.7277128570560034 1.0 0.9317311323148352 8 P07942 1 +Cerebral cortex radially oriented cell migration 0.3888394866879404 0.3481695464664727 0.7277128570560034 1.0 0.9317311323148352 8 P07942 1 +Response to acidic ph 0.4697844848078278 0.3479877294909986 0.7278493987241057 1.0 0.9317311323148352 4 Q9P2X3 1 +Intracellular protein transmembrane transport 0.3221418751789705 0.3468514008509905 0.7287029590976297 1.0 0.9324150789881668 26 O96008,Q15629,O95831,P31751,O75298,P11274 6 +Negative regulation of phosphoprotein phosphatase activity 0.3775641383918702 0.3462877197702904 0.7291264965889326 1.0 0.9324150789881668 9 O75116 1 +Response to dexamethasone 0.3661715535522309 0.3459726640089192 0.7293632585451486 1.0 0.9324150789881668 10 P25705 1 +Glycolipid catabolic process 0.3989584244937537 0.3454694112005126 0.7297415026492295 1.0 0.932719668550128 7 P06280 1 +Divalent inorganic cation homeostasis 0.2842404746400971 0.3448727635653201 0.7301900273740749 1.0 0.9331139532783777 65 Q9NWR8,P16615,Q9H4I9,Q7L0J3,Q6P4Q7,Q9HD20,Q8IYU8,P05067 8 +Folic acid containing compound metabolic process 0.3595103897179259 0.3442649276747078 0.7306470576865121 1.0 0.9335189540489416 13 P41440,Q9NRN7 2 +Vacuolar proton transporting v type atpase complex assembly 0.4851648351648367 0.3429274285040151 0.731653056602936 1.0 0.9342668294644236 3 Q3ZAQ7,Q92544 2 +Proton transporting v type atpase complex assembly 0.4851648351648367 0.3429274285040151 0.731653056602936 1.0 0.9342668294644236 3 Q3ZAQ7,Q92544 2 +Gene silencing by rna 0.294298374586798 0.3423556281137877 0.7320832767248842 1.0 0.9343023908250953 44 Q5TAX3,O75175,P51114,P22626,O75569,Q9HCE1,Q6ZN17,Q5KU26,Q99598,P55265,Q9Y2W6,Q9H7Z3,O75844,Q9UKZ1,Q8WYQ5 15 +Sensory perception of light stimulus 0.3235324226799281 0.3404621870261595 0.7335084941045611 1.0 0.9345565172013038 23 Q13432,O60313,Q15555,Q96RK4,P50897,O75569,Q92696,Q6P4Q7,Q9NWW5 9 +Dendritic cell differentiation 0.4666117065127987 0.3388972917028706 0.7346871047552401 1.0 0.9354519738169624 4 P01889,P09429,P17931 3 +Regulation of natural killer cell mediated immunity 0.3854227718531221 0.3360318178491724 0.7368468729782598 1.0 0.9368921465622312 8 P30511,Q9BY67 2 +Regulation of ion transmembrane transport 0.283299447164402 0.3357354223119528 0.7370703915661039 1.0 0.9368921465622312 65 P21796,P22466,O43865,Q9NRA0,O75844,P05067,P46939 7 +Negative regulation of macroautophagy 0.3572768921480644 0.3344259499159832 0.7380581603389025 1.0 0.937415463655758 13 P31749,Q14457,O15118 3 +Positive regulation of glucose metabolic process 0.4187948139318757 0.3325915691140975 0.7394426082822319 1.0 0.9374450958861348 6 P31751 1 +Positive regulation of cellular carbohydrate metabolic process 0.4187948139318757 0.3325915691140975 0.7394426082822319 1.0 0.9374450958861348 6 P31751 1 +Protein modification by small protein removal 0.2840485680246196 0.3290792419465684 0.7420957937603188 1.0 0.9382438178475896 52 Q96RU2,O00303,Q96K76,P19474,Q9H9Q2,Q86UV5,Q8NB14,Q9UNS2,P61201,Q9UBW8,Q93009,Q9BT78,Q9NZM5,Q9UPT9 14 +Positive regulation of axonogenesis 0.3289191552756796 0.3274541299183065 0.743324431214456 1.0 0.939239331912653 17 P07196 1 +Positive regulation of cellular component biogenesis 0.2767179131368638 0.3261674965164453 0.7442976318382772 1.0 0.9394307863115062 125 P26038,Q9NVN8,Q9BQT9,Q96C92,Q71SY5,Q9UQB8,Q16625,P02786,Q14203,O75116,Q14457,P23396,Q13464,Q13641,P09493,Q7L576,P41440,Q15555,Q9Y5X1,Q9NWH9,Q8NCA5,O95219,O75955,Q96RK4 24 +Regulation of defense response to virus by host 0.3926806490476662 0.3244103201451832 0.7456274075385385 1.0 0.9402659828769758 7 Q7Z434 1 +Regulation of cell cycle g1 s phase transition 0.2960116335124985 0.3230616002161615 0.7466485908206735 1.0 0.9409721128500372 40 Q06481,P31749,P31350,O00213,Q96HY6,P78536,Q9UL46,Q96DY7,Q8N7H5 9 +Regulation of mirna transcription 0.391914191419153 0.3218758819552113 0.7475467250632148 1.0 0.9412350500222793 7 P51532,Q9BVP2,P40763,P17844,P25490,P04637 6 +Positive regulation of transferase activity 0.2819728585071119 0.3211758458754502 0.7480771354728537 1.0 0.9412350500222793 113 Q05639,Q14012,P54619,P78371,Q16763,P14174,P40938,Q12834,Q13432,Q15375,Q92564,Q8NDZ4,P23396,Q8WXW3,Q9Y4G8,P12956,Q9BRT9,P78536,P31749,P49792,Q9Y5X1,Q9NWH9 22 +Regulation of sodium ion transport 0.3276922650469421 0.3211432398187563 0.7481018436681162 1.0 0.9412350500222793 17 P27105,P46939,O43865,O43707 4 +Dendrite morphogenesis 0.3076837417566476 0.3209762352609355 0.7482284003230713 1.0 0.9412350500222793 31 Q9UQB8 1 +Locomotion 0.3097142824161909 0.3209181842634265 0.7482723931670179 1.0 0.9412350500222793 274 Q92538,P07942,P42785,Q4VCS5,Q8WTV0,P84095,Q96N67,P14174,P02545,Q9Y5S2,Q96G23,P05067,Q00796,P35579,Q9UH99,Q06481,Q96JJ3,O75116,Q15375,P42892,P00813,O75592,Q13049,Q5SNT2,P33176,P55011,Q96TA1,Q13464,O43707,Q13641,Q9Y4G8,Q96EA4,Q9Y448,P09493,P78536,Q7L576,Q9BX67,Q9NWW5,P11274,Q9BZE4,Q14185,Q96HY6,Q96N66,Q9NUQ9,Q15555,Q96RK4,Q9NWH9,P25705,Q8NAT1,P15291,P57105,P31751,O95684,Q9BSJ2,P10586,Q99538,Q9UPN4,P07196 58 +Regulation of mitotic sister chromatid segregation 0.3203384142515238 0.3209053593344432 0.7482821124059709 1.0 0.9412350500222793 22 O60566,P12270,Q96EA4,Q9Y6D9,Q14457 5 +Microtubule based movement 0.2831725242322405 0.3205487470606437 0.7485523833210352 1.0 0.9412350500222793 84 Q9Y496,Q8TD16,Q9Y366,P05067,Q00796,O60313,Q86UP2,Q14203,Q9NXR1,O43805,Q5SNT2,P33176,P52732,Q14168,Q9Y678,Q96RK4,Q9UPN4,P07196,P23246,A0AVF1 20 +Negative regulation of phosphatidylinositol 3 kinase signaling 0.4594513182407993 0.3187937005129499 0.7498829555086104 1.0 0.9421739157727164 4 Q9NZM5,Q10713 2 +Positive regulation of cellular component organization 0.308752705651484 0.3181275009008755 0.7503882237185611 1.0 0.9421739157727164 271 Q14012,Q14108,P78371,P26038,Q9NVN8,Q9BQT9,Q96C92,Q71SY5,P14373,O75027,Q12834,O00291,Q9NY93,Q9UQB8,P05067,P21796,Q06481,Q8IY18,P02786,Q14203,O75116,Q14457,P23396,Q8N2A8,P50897,Q13464,Q13641,Q9Y4G8,P09493,Q7L576,P41440,Q15555,P17655,Q9Y5X1,O15260,Q96A26,Q8NCA5,Q9NWH9,P31751,O95219,O75955,Q96RK4,Q9H2U1,P07196,P23246,Q9GZY8 46 +Negative regulation of protein containing complex assembly 0.29120743144926 0.318081236182261 0.7504233164176712 1.0 0.9421739157727164 44 Q13045,Q15691,Q9NUQ9,Q9P2X3,P45880,Q01082,P04062,Q9NZM5,Q96RK4,Q9NYL9,Q9BX67,Q13813,Q9UEY8 13 +Forebrain cell migration 0.3577241943885116 0.3180720527328266 0.7504302823061393 1.0 0.9421739157727164 11 Q96N66,P07942,P35222,O94813 4 +Leukocyte differentiation 0.2802933342532641 0.3162137087918477 0.7518403030994882 1.0 0.9422976950115204 67 P35579,P02786,O00625,P12956,P00813,P05067,P78536 7 +Nucleoside bisphosphate biosynthetic process 0.3069126028867885 0.3159687879243965 0.7520261990246255 1.0 0.9422976950115204 31 Q9UKU0,O95563,P50897,Q9UMR5,P11177,Q9NVE7 6 +Positive regulation of catabolic process 0.2711604794461957 0.3157056467968094 0.7522259402320692 1.0 0.9422976950115204 166 P46379,O15269,P26038,P27544,O60506,P61956,P14373,Q92945,Q12834,Q8IZD4,P05067,Q5THJ4,P21796,Q9Y4X5,P19474,P09601,O75116,Q13868,Q9BXS4,Q6ZXV5,Q13049,Q14457,O94874,P48729,Q13464,Q6ZN17,O60858,P04062,P31749,Q5TAX3,O60826,Q9Y5X1,Q9HCE1,Q9NQT5,P31751,O95219,Q96HY6,Q9NZM5,Q9H2U1,O75175,Q15042 41 +Negative regulation of cell activation 0.318126984409954 0.3144942625972117 0.7531456733630355 1.0 0.9432724852665236 25 P22466,Q96FV9,Q8WXW3,P80404,P30511,P11274,Q9Y6D9 7 +Protein transport along microtubule 0.4127100106565843 0.3137723158599455 0.7536939720190128 1.0 0.9437817958208384 6 Q14168,P33176 2 +Regulation of type b pancreatic cell development 0.457459871201402 0.3133061748667455 0.7540480592715575 1.0 0.9440477675547516 4 P31749 1 +Endothelium development 0.3164294355077953 0.3127617218080387 0.7544616989440556 1.0 0.9443881833673196 26 O75116,Q9Y4G8,Q13464,Q9NWH9 4 +Negative regulation of lymphocyte mediated immunity 0.4118154368229352 0.3110455835769373 0.7557659684837634 1.0 0.9455122605164408 6 P30511,P04439 2 +Homeostatic process 0.3215756152503833 0.3110199874173914 0.7557854269113857 1.0 0.9455122605164408 335 P42785,Q9HCL2,O15118,Q8WTV0,Q9HC07,Q96H78,P30519,P14174,Q96N67,Q7L0J3,P10253,O75027,P39210,O14773,O75503,P00390,P05067,P11166,O95563,Q9NWR8,Q06481,Q9UIQ6,Q9Y487,P49748,P02786,P53985,P16615,O75787,P80404,Q6P4Q7,Q9HD20,P00813,Q9BPX6,Q96RR1,Q92542,Q13049,Q96CP7,P50897,P23786,Q16739,Q93050,P78536,O15254,P11274,Q9Y6M7,Q15051,Q15555,P61916,O15260,Q9H4I9,Q9NWH9,Q9NWW5,O60826,Q8IYU8 54 +Histone h3 k9 modification 0.35122022131756 0.3081777121199687 0.757947110833634 1.0 0.9465061960855105 13 P02545,Q9NRA0 2 +Nuclear ncrna surveillance 0.4105896261979671 0.307326157746175 0.7585951274559983 1.0 0.9465392011684112 6 Q13868 1 +Regulation of cellular response to heat 0.3768913342503579 0.3064552167250868 0.7592580723909133 1.0 0.9466200267883184 8 P42345,Q99615,P49841,Q99543,O75190,Q96EB6,Q9UHD1 7 +Negative regulation of adenylate cyclase activity 0.4237846745399568 0.3048217329212942 0.7605019282825776 1.0 0.9469783894842252 2 P04899 1 +Negative regulation of lyase activity 0.4237846745399568 0.3048217329212942 0.7605019282825776 1.0 0.9469783894842252 2 P04899 1 +Regulation of centrosome cycle 0.3173134301366311 0.3044256356056464 0.76080363963528 1.0 0.94698947335884 20 Q9HD42,O75116 2 +Negative regulation of hormone metabolic process 0.4229607250755245 0.3024348366306965 0.7623206015530954 1.0 0.9483461852405294 2 O60678 1 +Microtubule cytoskeleton organization 0.2800382649835348 0.3010090276441761 0.7634076105345013 1.0 0.949343954645648 189 O15344,Q9Y496,Q9HD42,Q8TD16,Q8WVM7,Q96N67,Q9H6D7,P02545,Q12834,P35579,Q9UH99,Q96CW5,Q9H3R5,Q08379,P53985,Q14203,O75116,Q96ED9,P29372,P23396,Q8WXW3,Q8IWJ2,Q13464,P52732,Q96EA4,Q9Y448,Q9UQE7,Q15555,O94927,Q9NWH9,Q96CS2,O95684,O43663,Q9BSJ2,Q9UPN4,P07196,A0AVF1 37 +Negative regulation of phosphatase activity 0.3533227190687573 0.3004154893061991 0.7638602502645644 1.0 0.949729585279491 11 O75116 1 +Spinal cord development 0.3434809267236615 0.2993497031532929 0.7646732345628775 1.0 0.950074356207364 14 O75530 1 +Negative regulation of protein polymerization 0.3066719925367558 0.2991819477020498 0.7648012224849565 1.0 0.950074356207364 30 Q9NUQ9,P45880,Q01082,Q96RK4,Q13813,Q9UEY8 6 +Insulin receptor signaling pathway 0.3066202783768381 0.2988572271674451 0.7650489841374568 1.0 0.950143780299697 30 Q9UQB8 1 +Negative regulation of smooth muscle cell migration 0.4298936110538638 0.2983233857516343 0.7654563571961337 1.0 0.9504725508754824 5 P09493 1 +Regulation of peptidase activity 0.2817640598402038 0.2980728190498292 0.7656475864041583 1.0 0.9505328616006906 87 P23396,Q96K76,Q06481,Q13464,Q96A26,Q15392,O95831,O75116,Q01664,Q96F07,Q15375,Q9BXK5,P61201,O00291,Q96HY6,Q99538,Q92542,P05067 18 +Endoderm development 0.348717117237003 0.2975209818492552 0.7660687916417517 1.0 0.9508786063168764 13 P07942,Q92541,P35222,Q8N7H5 4 +Meiotic cell cycle checkpoint signaling 0.4681318681318698 0.2972671573019991 0.7662625535829062 1.0 0.9509419621014908 3 Q08J23,P33981 2 +Positive regulation of spindle assembly 0.4210381763251797 0.2969055234578299 0.7665386391146429 1.0 0.9511074399293976 2 Q14980 1 +Regulation of neurotransmitter uptake 0.4512466727361409 0.2964830113602935 0.7668612390534566 1.0 0.9513305596375314 4 P41440 1 +Negative regulation of jun kinase activity 0.4202142268607457 0.2945531008497458 0.768335293423626 1.0 0.951980837062256 2 Q53EL6 1 +Regulation of cell cycle g2 m phase transition 0.2949273510633519 0.2939211956320519 0.768818121332266 1.0 0.9521615995640784 35 P11802,Q96K76,P06493,Q7LG56,O00311,Q9Y619,Q9NZM5,O14965,Q13642,P05067,P24941 11 +Nucleoside bisphosphate metabolic process 0.280124910475598 0.2933904689694723 0.769223709748253 1.0 0.9521615995640784 53 Q9UMR5,Q9HCL2,P50897 3 +Cardiac conduction system development 0.4664835164835182 0.2930254038311561 0.7695027340815388 1.0 0.9521615995640784 3 Q14126,P60953 2 +Positive regulation of inflammatory response 0.3144295090288236 0.2927065021811525 0.76974649945008 1.0 0.9521615995640784 18 O95219,P05067,P51809 3 +Regulation of potassium ion transport 0.3419519023355056 0.2926135176820328 0.7698175801968619 1.0 0.9521615995640784 14 P22466 1 +Regulation of stress activated protein kinase signaling cascade 0.3112547905229981 0.2914836233112012 0.7706814670862125 1.0 0.9525087815166796 27 O75844,P05067 2 +Cytoplasmic microtubule organization 0.3148800244309178 0.2913115565953535 0.7708130496680079 1.0 0.9525087815166796 20 Q96CW5,Q14203,Q9UJC3,Q96ED9,Q9BSJ2 5 +Double strand break repair via break induced replication 0.3512406199678028 0.2875399525343675 0.7736989151880975 1.0 0.9542673853666972 10 Q14566,Q9BRT9 2 +Response to muscle stretch 0.4478390060720601 0.2874512212582 0.7737668463062988 1.0 0.9542673853666972 4 P19022,P35222 2 +Negative regulation of inflammatory response 0.3407221454094601 0.2872288334855815 0.7739371101203316 1.0 0.9542673853666972 14 P00813,P28070 2 +Calcium mediated signaling 0.3140505554624635 0.2868745427271348 0.774208383538201 1.0 0.9542673853666972 20 P00813,P16615 2 +Positive regulation of keratinocyte differentiation 0.4257833974711325 0.2868316134823223 0.7742412554843712 1.0 0.9542673853666972 5 O75367,Q9P0M6,Q14980,Q15648 4 +Inorganic anion transmembrane transport 0.3497520758343732 0.2863399722445474 0.7746177457487808 1.0 0.9545548437070698 11 Q9UHG3,P55011,Q9UBX3,P51790,P51798 5 +Multicellular organism reproduction 0.2643433715224942 0.2856538092894404 0.7751432859361778 1.0 0.9550258347249913 138 Q8NB78,P46379,P54619,Q15102,P14373,P05067,P11717,Q9BY67,Q00536,O75718,Q9UHI6,P00813,O75592,Q9Y2W6,Q8N2A8,Q9BTX1,O15287,Q9BX67,P31749,Q96PU8,Q9BPZ3,Q9UJC3,P15291,Q9H2U1,Q96RK4,Q9UPN4,P26583,Q9P0K7,A0AVF1 29 +Negative regulation of immune response 0.3084185721804414 0.2848900044241649 0.7757284141190233 1.0 0.9552168588569676 28 P28070,P11274,P30511,P19474 4 +Endosome organization 0.2913085635102383 0.2831136622213179 0.7770897089298607 1.0 0.9561071013119468 39 Q14108,Q15075,Q9HD42,Q9NZZ3,Q86VS8,P51790,Q9UJC3,Q96ED9,O43752,P61020 10 +Biological process involved in intraspecies interaction between organisms 0.4024071711819473 0.2830104166520978 0.7771688519744115 1.0 0.9561071013119468 6 Q15334,Q15154,Q96RK4 3 +Response to virus 0.2812887284486244 0.2820657535948248 0.777893092126476 1.0 0.956174388619199 95 Q92538,P19474,Q9HCL2,P61916,O75569,O75844,Q9HCE1,Q7Z434,O60858,P14373,Q9H2U1,Q9NY93,O43657,Q13049,Q14457 15 +Retrograde transport vesicle recycling within golgi 0.4018158110077564 0.2812882331632806 0.7784893346971782 1.0 0.9563190333863012 6 Q96JB2,Q8TBA6 2 +Positive regulation of stem cell differentiation 0.4449813361477104 0.2799856914623527 0.7794884826005417 1.0 0.957017092236486 4 Q9H2U1 1 +Vesicle transport along microtubule 0.3477101915231191 0.2783935974483577 0.7807102338268304 1.0 0.95733692537142 11 Q9Y496,P33176 2 +Extracellular matrix disassembly 0.3684094573860028 0.278137150993504 0.7809070780607854 1.0 0.95733692537142 8 P41440 1 +Centrosome duplication 0.3120857321909133 0.2775299563338997 0.7813732070153294 1.0 0.95733692537142 24 Q9HD42,Q9NZZ3,O75116,Q9NXR1,Q9UPN4 5 +Negative regulation of mrna metabolic process 0.2846471546011174 0.2767729810782797 0.7819544289797538 1.0 0.9575591205734036 45 Q15287,O60506,P98175,P35637,O75150,Q08170,O75494,Q92804,P07910,O00267,Q9Y2W1,A2RRP1,Q9NZI8,Q6PD62,Q14103,P22626,Q13151,Q06787,Q16539,Q12872,Q6PJT7,Q99729 22 +Thioester biosynthetic process 0.3114566723924896 0.2763561196903916 0.7822745561835911 1.0 0.9575591205734036 25 Q9UMR5,P50897 2 +Intraciliary retrograde transport 0.4133479813238001 0.2753584828228558 0.783040837482766 1.0 0.9578485588668386 2 Q8NCM8 1 +Carbohydrate derivative biosynthetic process 0.2773807863239313 0.2735025447723261 0.7844669364435537 1.0 0.958185737401173 187 P55263,O15118,Q9HC07,O60476,Q13126,Q99805,Q9NVE7,Q9UKU0,O95563,Q8NCH0,Q8WVQ1,Q96L58,Q08379,Q9BXS4,Q6ZXV5,P00813,Q969N2,Q92542,P50897,Q8NBX0,P00846,Q16739,Q9UMR5,O43505,Q7LG56,P31350,Q9H9S5,O60502,O60512,O75964,P04843,Q9NRA0,P25705,P15291,Q9NQX7 35 +Retina layer formation 0.4125240318593726 0.2731047765948378 0.7847726750662507 1.0 0.9583834922958996 2 O75147 1 +Process utilizing autophagic mechanism 0.278160926733476 0.272880491690132 0.7849450829860967 1.0 0.9584183778516332 189 Q8WUH2,P27544,O15118,Q9HD42,Q07820,P14373,P21796,P19474,Q08379,Q9Y487,P16615,Q96GC9,Q9BXS4,Q8NHS3,Q13049,P10619,Q14457,O94874,P07602,Q13464,O60858,Q93050,Q9H300,Q9NZ45,P51809,Q9NWH9,Q969Q5,O95219,Q96HY6,O75844 30 +Neuron intrinsic apoptotic signaling pathway in response to oxidative stress 0.4420712184141593 0.2724862617240114 0.7852481533306421 1.0 0.958612760286198 4 Q07820 1 +Negative regulation of histone h3 k27 methylation 0.4579670329670345 0.2716270327959141 0.7859088115241939 1.0 0.9587434895455892 3 O75367,Q7KZ85 2 +Muscle cell apoptotic process 0.3311994995475263 0.271598434999815 0.7859308029263108 1.0 0.9587434895455892 15 Q8NDZ4 1 +Positive regulation of intracellular steroid hormone receptor signaling pathway 0.41946124244088 0.269579691746462 0.7874836257254527 1.0 0.959408191297987 5 Q16512,Q969T9,Q15648,P09874 4 +Positive regulation of exocytosis 0.3108603501015869 0.268984347736816 0.7879417276199892 1.0 0.959790810078974 21 P30511,Q9NRA0 2 +Mechanoreceptor differentiation 0.3561064557157133 0.2684536708799931 0.7883501316538999 1.0 0.959910738580186 9 P54802 1 +Actomyosin structure organization 0.2776884235556701 0.268294836247535 0.7884723806467595 1.0 0.959910738580186 57 P35579,Q13045,P35580,Q96RK4,Q7Z406,Q13464,Q9NWH9,Q13136,O75116,P09493,Q9Y5S2 11 +Fat cell differentiation 0.2993189670319018 0.2676145088967304 0.7889960617182112 1.0 0.9599576987178589 31 Q9BRK5,Q9NZ08,Q13049,Q99523 4 +Establishment or maintenance of bipolar cell polarity 0.3103535040402443 0.2673089214945801 0.7892313182615085 1.0 0.9599576987178589 20 Q14168,Q8N3R9 2 +Modulation by host of symbiont process 0.3101723464550759 0.2655911386367775 0.7905541109132306 1.0 0.9605128864998684 23 P11717,Q13573 2 +Mitochondrial acetyl coa biosynthetic process from pyruvate 0.4179021195365791 0.2654057049955863 0.790696941758326 1.0 0.9605128864998684 5 O95563 1 +Positive regulation of cell projection organization 0.2739480190921757 0.2631550717341668 0.7924310581777594 1.0 0.9608677235010756 74 Q14012,Q14108,Q15555,Q7L576,Q96C92,Q8NCA5,Q9Y4G8,Q9H2U1,Q96RK4,Q9NY93,Q9UQB8,P07196,Q16625 13 +Cellular response to xenobiotic stimulus 0.3028505386023302 0.2628446377765204 0.7926703288339274 1.0 0.9609829696179872 29 P07099,P02786,O43169,Q6PIU2,Q6N069 5 +Torc2 signaling 0.4084042845372121 0.2619983012039534 0.7933227519001957 1.0 0.9610744538020008 2 Q96A49 1 +Monoubiquitinated protein deubiquitination 0.3419488500356247 0.2616966517472719 0.7935553221193008 1.0 0.96109331344661 12 Q96K76,Q9UPT9 2 +Phosphatidylinositol dephosphorylation 0.4537928989750073 0.2614617057979557 0.7937364769885455 1.0 0.96109331344661 3 Q10713 1 +Positive regulation of neural precursor cell proliferation 0.3948670404219776 0.2614168689552433 0.7937710496618182 1.0 0.96109331344661 6 P48681,P55209,P35222 3 +Import into cell 0.2928484928934755 0.2589336631041778 0.7956864242876283 1.0 0.9625378803610144 33 P11166,P55011,Q01650,P31751,Q15758,P30825,O75955,P41440,Q9Y666,P31749 10 +Vasculature development 0.2778500618617002 0.2578062714333677 0.7965564241605618 1.0 0.9630657692218876 109 P35579,P42785,Q96TA1,O94788,Q9NZ08,O75116,Q9Y4G8,P15291,P57105,Q9H2J4,P32929,Q9NRA0 12 +Negative regulation of dna damage checkpoint 0.4131999489015775 0.2530140330231792 0.8002573691560795 1.0 0.9653752189062896 5 Q96FV9 1 +Negative regulation of cell cycle checkpoint 0.4131999489015775 0.2530140330231792 0.8002573691560795 1.0 0.9653752189062896 5 Q96FV9 1 +Glycine biosynthetic process 0.4500000000000019 0.2524125068369711 0.8007222339995583 1.0 0.9653752189062896 3 P34897,P00374 2 +Negative regulation of signal transduction in absence of ligand 0.369552373531762 0.2516811601928935 0.8012875203264258 1.0 0.9653752189062896 7 Q07820,P35221 2 +Biological process involved in symbiotic interaction 0.277147207719681 0.2514841400331308 0.8014398226914108 1.0 0.9653752189062896 86 P11717,Q14108,P19474,O15118,Q8WTV0,Q9HD42,Q01664,Q9BTY2,P14373,Q13573 10 +Oogenesis 0.3204152124452351 0.2513944131567988 0.8015091867011248 1.0 0.9653752189062896 16 Q96MU7,Q8N2A8,Q5TAX3,Q9UHI6,Q9Y2W6,P35222 6 +Platelet activation 0.3201811513891273 0.2503210743987289 0.8023390601372167 1.0 0.9656964548792925 16 P35579,P12814 2 +T cell chemotaxis 0.4112612877246855 0.2479920815329321 0.8041405334962772 1.0 0.9660139526341168 5 P78536 1 +Lymphocyte chemotaxis 0.4112612877246855 0.2479920815329321 0.8041405334962772 1.0 0.9660139526341168 5 P78536 1 +Organelle fission 0.2692624417653539 0.2478358984971167 0.80426137823845 1.0 0.9660139526341168 172 Q13123,Q86XL3,P46379,Q6NUK4,Q96EE3,Q92878,Q9HD42,Q9UIG0,Q8N3U4,Q16763,Q02241,Q8WVM7,O95347,P11233,Q9NTJ3,Q12834,P50748,Q9Y6D9,Q14683,Q9NTI5,Q14807,O60313,O60566,Q8IY18,Q08379,P12270,Q9NXR1,Q15021,Q96DY7,Q9Y2W6,Q14457,Q12768,Q96DB5,Q9BTX1,Q9NZZ3,Q8WXW3,Q9UJX3,P52732,Q9Y3D6,Q96EA4,Q9Y448,Q29RF7,O95239,Q9UQE7,Q9NUQ9,Q96IY1,Q9Y6A5,Q96HS1,Q9HC35,O43663,Q6ZVM7,Q9BS16,Q9GZY8 53 +Regulation of epidermis development 0.3382845142880918 0.2474378034936967 0.8045694206012368 1.0 0.9660139526341168 12 O75116 1 +Inner ear receptor cell development 0.3587361142776237 0.2472439821132484 0.8047194088430125 1.0 0.9660139526341168 8 P54802 1 +Regulation of inflammatory response to antigenic stimulus 0.3897332912012041 0.2471774597797722 0.8047708886590854 1.0 0.9660139526341168 6 P28070 1 +Lysine metabolic process 0.4318035921061969 0.2468760860045623 0.8050041241894734 1.0 0.9660139526341168 4 Q9NRN7 1 +Positive regulation of interleukin 2 production 0.3679178513970237 0.2468491063432929 0.8050250048077277 1.0 0.9660139526341168 7 Q01082 1 +Inner cell mass cell proliferation 0.3886689605831751 0.2442732927543203 0.8070191663397706 1.0 0.967585936293126 6 Q9BRT9 1 +Interferon alpha production 0.3668663465937856 0.2437631223577871 0.8074142829650175 1.0 0.967585936293126 7 Q9H2U1,Q7Z434,P42224 3 +Positive regulation of interferon alpha production 0.3668663465937856 0.2437631223577871 0.8074142829650175 1.0 0.967585936293126 7 Q9H2U1,Q7Z434,P42224 3 +Regulation of vacuole organization 0.3301003653481725 0.2419989149969083 0.8087810039548344 1.0 0.9683572020397236 14 O95219,Q14457 2 +Regulation of transporter activity 0.2760275237287262 0.241246078028036 0.8093644001906515 1.0 0.9684527092897066 48 P22466,P05067,O43865,Q9NRA0,P46939 5 +Mitochondrial proton transporting atp synthase complex assembly 0.4084090790691271 0.2406972233292103 0.8097897911747631 1.0 0.9684527092897066 5 Q15070 1 +Negative regulation of binding 0.2829757591476354 0.2404595209180488 0.8099740403742968 1.0 0.9684527092897066 42 Q14012,Q9NVN8,Q08379,P16615,Q13464,Q01664,P30533,Q92797,P10586 9 +Chloride transmembrane transport 0.355940713347747 0.2386068889130696 0.8114104228279879 1.0 0.9688037701254107 8 Q9UHG3,P55011,P51798,P51790 4 +Regulation of monocyte chemotaxis 0.4067036393805691 0.2363890390852208 0.8131308007573077 1.0 0.9692880732508142 5 Q99538,O94813,Q8NHP6 3 +Axis elongation 0.4428571428571447 0.2358642296662713 0.8135380257856941 1.0 0.9692880732508142 3 Q15648,Q13263 2 +Convergent extension 0.4428571428571445 0.2358642296662707 0.8135380257856946 1.0 0.9692880732508142 3 O14641,Q13263 2 +Regulation of rna export from nucleus 0.3370073214077112 0.235474911097229 0.8138401494808751 1.0 0.9692880732508142 10 Q9H7Z3,Q07666 2 +Oocyte maturation 0.3853217136100921 0.2352487733899427 0.8140156523138242 1.0 0.9692880732508142 6 Q12768,Q5TAX3 2 +Determination of adult lifespan 0.363920375694607 0.2352120253325972 0.8140441729339778 1.0 0.9692880732508142 7 O75844 1 +Positive regulation of cell matrix adhesion 0.3334398494784862 0.2350864647625832 0.8141416238995947 1.0 0.9692880732508142 13 P46939 1 +Regulation of intracellular signal transduction 0.3114251569192631 0.2342159014412839 0.8148173707515216 1.0 0.9694871680923908 305 Q92538,Q4VCS5,Q07820,P14174,Q9Y6D9,Q9UMX5,P05067,O60313,P19474,Q8TB61,P00813,O43657,O94874,Q8NDZ4,Q15233,Q8WUK0,P45880,O60858,Q9Y4G8,P41440,P31749,Q9NUQ9,Q9UNS2,Q96FV9,Q96EE3,Q86VI3,P09601,P12270,A1A4S6,Q10713,Q13769,P32929,Q13049,Q14457,Q9NYF8,P55735,Q9Y2U8,P04062,Q9NRA0,P35222,P46940,Q13325,Q5T9L3,P57105,O75955,O60826,Q9NZM5,O75844,O15344,O94813,P42224,Q92734,Q07960,O75787,O95140,O75116,Q02952,Q13043,Q96RT1,Q13464,O43707,Q13641,Q9NRZ9,Q9Y3T9,Q9Y3D6,P19022,P11274,Q15555,O75569,Q9NWH9,P23246,P14373,O00291,Q9NY93,Q92888,Q8WVQ1,P02786,Q7Z434,Q15375,P29372,P23396,Q8N2F6,Q7LG56,Q9H300,Q96K76,Q93009,Q9H2U1 87 +Negative regulation of vascular associated smooth muscle cell proliferation 0.4050567003647415 0.2322670642501811 0.8163305918936983 1.0 0.9704247756055432 5 P09601,Q53EL6,P09493 3 +Primary mirna processing 0.3838840345641044 0.2314237987601369 0.8169855781878739 1.0 0.971026562159437 6 P22626,O00571,Q8WYQ5,Q6ZN17 4 +Developmental growth involved in morphogenesis 0.2747387368552585 0.2311801237617036 0.8171748707394346 1.0 0.9710783241906282 48 Q9NZM3,Q8N0X7,Q96F07,Q15375,Q7L576,P05067 6 +Positive regulation of response to cytokine stimulus 0.3337804185935478 0.2302796799785515 0.8178744493757979 1.0 0.9713131636778274 12 P78536,Q13049 2 +Golgi disassembly 0.403811598129792 0.2291760145073558 0.8187321141551409 1.0 0.971879431422453 5 Q92538,Q08379 2 +Head morphogenesis 0.3829663736145813 0.2289985440688731 0.8188700477270976 1.0 0.971879431422453 6 O75787,O95470 2 +Phagosome acidification 0.3952210931062828 0.2283109396549573 0.8194045205193496 1.0 0.9719943600178792 2 Q14964 1 +Apical junction assembly 0.3028216149172756 0.2271262299398516 0.8203255884328249 1.0 0.97231529576488 21 O75116,Q13464,Q16625 3 +Mesonephric tubule morphogenesis 0.4229183841714951 0.2258125040370678 0.8213472514338049 1.0 0.9725673958243188 4 Q9BRK4,Q13418,P35222 3 +Amyloid beta clearance 0.332513446076114 0.2255281844307993 0.8215684020679088 1.0 0.9726564077786916 12 Q16850,Q13464 2 +Mitochondrial calcium ion homeostasis 0.3260046149468544 0.2252004184996451 0.8218233638954464 1.0 0.9727854101324142 14 Q16891,Q9NWR8,Q9H4I9,Q9BPX6,Q8IYU8 5 +Neuronal stem cell population maintenance 0.4017276800362248 0.2240513933584916 0.8227173134570749 1.0 0.9729793147966792 5 Q9NZI8,Q86VS8 2 +Regulation of endodeoxyribonuclease activity 0.3807545300511321 0.2232051444124415 0.8233758482763758 1.0 0.9732398930398248 6 P23396 1 +Regulation of core promoter binding 0.4367040871802243 0.2221346481377791 0.824209066256409 1.0 0.9734382901608836 3 P35222 1 +Positive regulation of deoxyribonuclease activity 0.4209027040122212 0.2211792956834805 0.8249528297051842 1.0 0.9734382901608836 4 P23396 1 +Ovulation cycle process 0.4003102851556974 0.2206009711638686 0.8254031448107522 1.0 0.9734382901608836 5 O75592,O95470 2 +Anaphase promoting complex dependent catabolic process 0.3321952537415786 0.2205969872231823 0.8254062471243164 1.0 0.9734382901608836 11 Q16763,Q12834 2 +Negative regulation of mirna transcription 0.3913759956055999 0.2190289131401007 0.826627525123772 1.0 0.9735861212677306 2 P25490 1 +Epithelial cell development 0.2730552233076554 0.2181481833091131 0.8273136564568349 1.0 0.9735861212677306 48 P08670,Q13464,O75116,Q9Y4G8,P15291 5 +Proton transporting two sector atpase complex assembly 0.3490124511055857 0.2177819262259597 0.8275990273630012 1.0 0.9735861212677306 8 Q15070 1 +Regulation of apoptotic signaling pathway 0.2747518597696627 0.2172807791840856 0.8279895352817104 1.0 0.97368412876492 107 Q07820,P14174,P02545,O60313,P35221,P09601,P32929,Q13049,Q14457,P23396,Q9NYF8,Q9H3K2,Q15233,Q8N2F6,Q8WUK0,Q7LG56,P45880,Q9H300,P31749,Q96K76,O75569,Q9NQX7,P26583,P23246 24 +Regulation of response to dna damage stimulus 0.2732304940415759 0.2166148186043593 0.8285085363467233 1.0 0.9741085925836334 84 Q9UNS2,P14174,Q7Z4V5,O96028,Q13049 5 +Positive regulation of sodium ion transport 0.3313513835197379 0.2158600928797971 0.8290968049845506 1.0 0.9741686915130282 10 O43865 1 +Regulation of mrna 3 end processing 0.2995094531888138 0.2143094189393709 0.8303057734188939 1.0 0.975203132080044 19 Q96MU7,Q6PJT7,O75150,Q9H2U1,O43865,Q8N684,Q6PD62,Q8N7H5 8 +Golgi to plasma membrane protein transport 0.2998535334426372 0.2137285457359299 0.8307587493836268 1.0 0.9755293097272232 20 Q9BZG1,Q01082,Q4J6C6 3 +Negative regulation of organ growth 0.3965190314203183 0.2115126940673028 0.8324872278427482 1.0 0.9755293097272232 5 P11413,Q13043 2 +Development of primary female sexual characteristics 0.3295839831863119 0.2113408405737585 0.8326213163842646 1.0 0.9755293097272232 11 P35221,O94813,O95470,O15287,P49770 5 +Macromolecule deacylation 0.2779257551904729 0.210856602324332 0.8329991690473371 1.0 0.9755293097272232 43 Q9NRA0,Q9UMR5,P50897 3 +Regulation of notch signaling pathway 0.3385620718512503 0.2106400002384557 0.8331681968453779 1.0 0.9755293097272232 9 Q96TA1,P57105 2 +Negative regulation of activated t cell proliferation 0.3878055479263829 0.2106335096705861 0.8331732619497911 1.0 0.9755293097272232 2 P10644 1 +Regulation of transcription regulatory region dna binding 0.3284080924294729 0.2103635360722848 0.8333839498727553 1.0 0.9755293097272232 12 Q96TA1,Q96L73,O75844,Q96HY6 4 +Glial cell differentiation 0.2787053799790932 0.2101130406949597 0.8335794476563927 1.0 0.9755293097272232 42 P08670,P05067,Q92542,Q8N3R9 4 +Mononuclear cell migration 0.2967956900549811 0.2092202921608439 0.8342762720999026 1.0 0.9755293097272232 27 P55011,P26038,Q99538,P78536,P04062,P05067,P31749 7 +Mitochondrial gene expression 0.2697888545933182 0.2090080875035666 0.8344419251343309 1.0 0.9755293097272232 65 P82912,Q9BSK2,P46199,Q9Y3D3,Q9BT17,O00411,Q567V2,Q9BRT2,Q96RR1,Q9Y2R0,Q9NWS8 11 +Negative regulation of smooth muscle cell proliferation 0.3541061368897922 0.2077554111377133 0.8354199496552088 1.0 0.9760482420748128 7 P09601,P09493,Q53EL6,O95140 4 +Neutrophil migration 0.3043183534983891 0.2075554738546786 0.8355760738774678 1.0 0.9760594986405272 17 Q92538,O94813,P84095,P35613,Q9BX67 5 +Protein localization to microtubule 0.3371475696327299 0.2062275119854078 0.836613198263326 1.0 0.9765861492691909 9 Q15555,O15344 2 +Cell migration involved in sprouting angiogenesis 0.3447796672822597 0.2054765733747643 0.8371997993435583 1.0 0.976928592473928 8 P09601,O94813,P31749 3 +Inositol phosphate catabolic process 0.4137967061107425 0.2052815842065238 0.8373521313470496 1.0 0.9769352567265612 4 Q9NX62 1 +Golgi to plasma membrane transport 0.2867306505996875 0.204829150488688 0.8377056110477179 1.0 0.9771765557442128 32 Q4J6C6,Q01082,Q9BZG1,O60826,Q567U6 5 +Cellular extravasation 0.3365247133987009 0.2042967333581622 0.8381216225457924 1.0 0.9774907003365332 9 P11274,Q13464 2 +Maintenance of blood brain barrier 0.3360448039592614 0.2028141817235504 0.8392802728862503 1.0 0.9783282817076776 9 Q9BX67,P55011 2 +Cell migration 0.2914105237242085 0.2018517881698704 0.8400325936333495 1.0 0.9785860931606164 238 Q92538,P07942,P42785,Q4VCS5,Q8WTV0,P84095,Q96N67,P14174,P02545,Q9Y5S2,Q96G23,P05067,P35579,Q9UH99,Q06481,Q96JJ3,O75116,P00813,Q13049,Q5SNT2,P55011,Q13464,O43707,Q13641,Q9Y4G8,Q96EA4,Q9Y448,P09493,P78536,Q9BX67,Q9BZE4,P11274,Q14185,Q96HY6,Q96N66,Q9NUQ9,Q15555,Q96RK4,Q9NWH9,P25705,Q8NAT1,P15291,P57105,P31751,O95684,Q9BSJ2,P10586,Q99538 48 +Regulation of synaptic vesicle exocytosis 0.3259552792201521 0.2014751040538494 0.8403270943735843 1.0 0.978692436603949 12 P16615,Q4J6C6 2 +Positive regulation of protein localization to cell periphery 0.2968076732916941 0.1987709408058056 0.842441928266896 1.0 0.980641259266654 20 P84095,P15311,Q01082,O00264,O15258,O43491,P17931,P31749,P33176 9 +Positive regulation of gtpase activity 0.276970220446125 0.1980102948626014 0.8430370090719519 1.0 0.9808116455607184 42 Q15555,P84095,Q9Y5X1,Q9Y4G8,P31751,P11274 6 +Positive regulation of fat cell differentiation 0.3421026757577154 0.197861195134862 0.8431536656936798 1.0 0.9808116455607184 8 Q13043,Q92766,Q16539,Q96A49,P31749 5 +Purine nucleoside monophosphate metabolic process 0.2957398946421748 0.1968300447727573 0.8439605386851567 1.0 0.9810851466569276 26 P00813,P55263 2 +Neutrophil homeostasis 0.4239897263772993 0.1953397960402978 0.8451269443639784 1.0 0.982051069113566 3 Q9BX67 1 +Positive regulation of protein modification process 0.2796245004086184 0.1951245930133049 0.8452954101594159 1.0 0.9820755567379578 206 Q14012,Q86XL3,P54619,P51114,Q86VI3,Q16763,P14174,P02545,Q96N67,Q92797,Q12834,P05067,Q08379,P02786,Q7Z434,O75116,Q15375,Q92564,O75592,Q8NDZ4,P23396,Q8WXW3,Q9Y4G8,P12956,Q13573,P78536,P41440,Q9H223,Q9NRA0,Q9Y5B6,P49354,Q9Y5X1,P31751,Q92541,O75955,Q96HY6 36 +Dna strand elongation 0.2965168948694737 0.1944881661961159 0.8457936608289267 1.0 0.9823837360794864 22 Q9H981 1 +Negative regulation of transport 0.2729651385841354 0.1942286518457927 0.8459968491116037 1.0 0.9823837360794864 93 P21796,Q16850,Q06481,P30511,Q07960,P80404,P14373,P31751,P00813,Q7L576,P11274,P05067 12 +Activation of cysteine type endopeptidase activity 0.4081011337577361 0.1930359678302594 0.8469307995529629 1.0 0.9825359295130413 4 Q96F07 1 +Segment specification 0.4228021978021997 0.1929470786643951 0.8470004142736649 1.0 0.9825359295130413 3 O14641,Q9Y483 2 +Protein localization to adherens junction 0.388125343595384 0.1921316227969727 0.8476391049248984 1.0 0.9825359295130413 5 Q07157,Q5T2T1,Q13112,P18206 4 +Positive regulation of membrane permeability 0.3125796743803116 0.1920299541058185 0.847718742062197 1.0 0.9825359295130413 15 Q9BX67,P45880 2 +Regulation of response to wounding 0.2960161595522721 0.1920053992301937 0.8477379761418504 1.0 0.9825359295130413 22 P55011,P80404,P10586,Q96G23,O14936 5 +Negative regulation of protein sumoylation 0.4069272151245138 0.190567530403765 0.8488644309288196 1.0 0.9832519207543934 4 Q9NVN8 1 +Positive regulation of glial cell differentiation 0.3473597359736089 0.189827208609354 0.8494445341496462 1.0 0.9832519207543934 7 P42345,Q9UPY3,Q92769,Q13547,Q15382,Q9UMS4 6 +Negative regulation of cell killing 0.3673252529392266 0.1896475643882675 0.8495853125258117 1.0 0.9832519207543934 6 P30511 1 +Response to arsenic containing substance 0.3169456047828534 0.1893999402763653 0.8497793712736428 1.0 0.9832519207543934 14 P09601,Q9H2U1,P07196 3 +Acetyl coa biosynthetic process from pyruvate 0.338457608250573 0.1877031629490155 0.8511093506691658 1.0 0.9833962352099038 8 P11177,O95563 2 +Regulation of protein secretion 0.2669607373963346 0.1873903991814261 0.8513545496175701 1.0 0.9833962352099038 52 O95563,Q16850,P55011,P35580,P80404,P53985,Q9BRT2,O14523,Q96KC8,O75592 10 +Negative regulation of bmp signaling pathway 0.3856862985605678 0.1866936052213255 0.8519008702432893 1.0 0.98357572317294 5 Q8N0X7 1 +T helper 17 type immune response 0.3768195550672809 0.186167959119878 0.852313049602841 1.0 0.9837106962590906 2 P40763 1 +Negative regulation of vascular associated smooth muscle cell differentiation 0.3765449052458082 0.1855829437455903 0.8527718301200053 1.0 0.9840697443868368 2 Q53EL6 1 +Polyadenylation dependent rna catabolic process 0.3452629644709102 0.1844159395114647 0.8536871663445922 1.0 0.9844583603788306 7 Q13868 1 +Response to uv a 0.4184134654852421 0.1842690113427654 0.8538024229958079 1.0 0.9844583603788306 3 P27544 1 +Regulation of osteoblast proliferation 0.375720955781374 0.1838357263140925 0.8541423282038414 1.0 0.9844583603788306 2 P06756 1 +Inflammasome complex assembly 0.3757209557813724 0.1838357263140891 0.8541423282038441 1.0 0.9844583603788306 2 O00571 1 +Mitochondrial cytochrome c oxidase assembly 0.3366787796901842 0.1828353707720896 0.8549271945182597 1.0 0.985073596728286 8 Q9Y2R0 1 +Sphingosine biosynthetic process 0.3839050348698424 0.1827778534406139 0.8549723262613955 1.0 0.985073596728286 5 P04062,Q9NRA0 2 +Positive regulation of mitotic cell cycle spindle assembly checkpoint 0.3835138917875086 0.1819243207519948 0.8556421177812208 1.0 0.9855044824159506 5 P12270,Q9Y6D9 2 +Positive regulation of oxidative stress induced cell death 0.3636168711998545 0.1808809039687945 0.8564610580302348 1.0 0.9862289946166394 6 P23246 1 +Tight junction organization 0.2915650121562299 0.1795612615923719 0.8574970190638096 1.0 0.9862289946166394 18 O75116,Q13464 2 +Negative regulation of actin filament polymerization 0.2935957534936958 0.1795299420587298 0.8575216088784123 1.0 0.9862289946166394 23 Q9NUQ9,Q01082,Q96RK4,Q13813,Q9UEY8 5 +Negative regulation of fatty acid biosynthetic process 0.3427243489135023 0.1779677600834512 0.8587482952401291 1.0 0.9862289946166394 7 P49748 1 +Lamellipodium morphogenesis 0.3347582603948731 0.1776463067509763 0.8590007553738919 1.0 0.9862289946166394 8 Q92766,Q13596,Q8IZP0,Q9Y6W5,O60749 5 +Positive regulation of molecular function 0.3121800323082277 0.1776255447953607 0.8590170617082178 1.0 0.9862289946166394 328 Q14012,P54619,P78371,Q8WTV0,P84095,Q96N67,P14174,Q71SY5,P14373,P40938,Q12834,O00291,O75503,P05067,P60900,P19474,P22466,P02786,Q7Z434,O95831,O75116,Q15375,Q92564,P32929,Q13049,Q92542,Q8NDZ4,Q96D46,P23396,P20585,P07602,Q96TA1,Q13464,Q01664,O43707,O60858,Q9Y4G8,Q96F07,P12956,Q9BXK5,Q9BRT9,P09493,P78536,P41440,Q8IXB1,P11274,Q15555,P49354,Q9Y5X1,Q9NWH9,Q96A26,P31751,O75955,Q96HY6 54 +Positive regulation of cytoskeleton organization 0.2668143118327035 0.1775954699201495 0.8590406824688646 1.0 0.9862289946166394 56 P23396,Q9Y5X1,Q9NWH9,Q14203,O75116,P14373,P09493,Q7L576,Q9UQB8,Q16625 10 +Histone h3 k36 trimethylation 0.4148351648351667 0.1773860511413741 0.8592051631517315 1.0 0.9862289946166394 3 Q9BZ95,O60885 2 +Microtubule bundle formation 0.3035078977427442 0.1773525521003346 0.859231474373344 1.0 0.9862289946166394 16 Q9UPN4,Q15555,O43663 3 +Activin receptor signaling pathway 0.4140052793896517 0.1758145424735606 0.8604396443607036 1.0 0.9866423853411224 3 Q9Y2U8 1 +Regulation of activin receptor signaling pathway 0.4140052793896517 0.1758145424735606 0.8604396443607036 1.0 0.9866423853411224 3 Q9Y2U8 1 +Regulation of epithelial cell differentiation 0.2923854228056151 0.1755723129565432 0.8606299554887327 1.0 0.9866423853411224 21 P35611,Q13464,O75116,P42224,Q15910,P35222 6 +Regulation of developmental growth 0.2667708953576689 0.1752388137991123 0.8608919871722591 1.0 0.9866423853411224 58 Q9NZM3,Q9HCL2,Q8N0X7,Q15375,Q96RK4,Q7L576,O75844,P05067 8 +Regulation of cell death 0.3183109201077845 0.1748207436831115 0.8612204882401271 1.0 0.9866423853411224 378 Q99720,P46379,Q86XL3,Q9HCL2,P98175,O15118,Q9HD42,O94788,Q01105,P30511,P14174,P02545,O00291,Q9UMX5,P11717,P21796,P22466,P02786,Q15392,O95831,Q15375,P00813,P32929,Q13049,Q14457,Q8NDZ4,P23396,P12814,Q9P2X3,P50897,Q96TA1,Q8N2F6,Q13464,Q01664,P45880,O43707,O60858,Q9Y4G8,Q7LG56,P52756,Q9BXK5,P30533,P78536,Q9H300,Q9NRA0,Q6N069,Q96K76,O75569,P17655,Q9NWH9,Q96A26,Q53T59,P15291,P31751,Q96HY6,Q99538,Q9NQX7,P07196,P23246 59 +Telomere maintenance 0.2658903277573188 0.1742027707055554 0.8617061081240804 1.0 0.9867047170578656 65 Q9UQ84,P78371,Q9NVN8,Q8IY18,Q93009,P12956,P41440 7 +Renal system process 0.318148117139233 0.1740669661410221 0.8618128340381306 1.0 0.9867047170578656 12 Q9NQH7,P11274,Q7LG56 3 +Circulatory system development 0.2654635025631335 0.1734478588858217 0.8622994091792084 1.0 0.9870298854769054 175 P42785,O94788,P02545,P10253,Q9Y366,P35579,O75116,P42892,Q9H2J4,Q9BQ70,O75592,P32929,Q8NDZ4,Q96TA1,Q9Y4G8,P09493,O96028,Q9NRA0,Q9NZ08,P15291,P57105,O75844 22 +Positive regulation of organelle organization 0.2626960667068118 0.1716489530796863 0.863713519570878 1.0 0.9877762178485918 169 P78371,P26038,P27544,Q92878,Q96C92,P14373,Q9NTJ3,Q9UQB8,Q16625,Q5THJ4,P21796,Q8IY18,P12270,Q14203,O75116,Q15021,Q9Y6W5,Q14457,P23396,Q8N2A8,Q9UJX3,P09493,Q7L576,P35222,Q15691,Q15555,Q9Y5X1,O15260,Q96A26,Q9NWH9,Q96HS1,P31751,O95219,Q96RK4,Q9H2U1,P23246,Q9GZY8 37 +Neutrophil chemotaxis 0.3122211879379534 0.1715031195188479 0.8638281777624819 1.0 0.9877762178485918 14 Q92538,O94813,Q8NHP6,P63000,P35613,Q00013,Q9BX67,P17931 8 +Neutrophil mediated immunity 0.3323685674981657 0.1712866436564077 0.8639983820818633 1.0 0.9877762178485918 8 P78536,P11274 2 +Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay 0.3785028392960663 0.1711916918639323 0.8640730399960708 1.0 0.9877762178485918 5 A2RRP1,Q9Y5S9 2 +Response to catecholamine 0.2905412012196671 0.1688809350573192 0.8658902954128689 1.0 0.9882540319177708 20 P05067 1 +Dna topological change 0.3579489989180664 0.167909247290301 0.8666546751327702 1.0 0.9886184044529444 6 P26583,P09429,P11387 3 +Negative regulation of epithelial cell differentiation 0.3758781219696554 0.1657205645617652 0.8683768616525642 1.0 0.9898232320380675 5 P42224,P35222 2 +Negative regulation of natural killer cell mediated immunity 0.3757453364116092 0.1654465390421231 0.8685925254986737 1.0 0.9898232320380675 5 P30511 1 +Cytokinesis 0.2622305723644578 0.1650169946547179 0.8689306056340411 1.0 0.9900281507078686 71 P35579,P35580,Q9HD42,Q96C92,Q13464,Q9Y5X1,O75116,Q01082,O75935,Q14457,Q6DKK2 11 +Negative regulation of immune effector process 0.3140813202316729 0.1630913323497167 0.8704465242097721 1.0 0.99107744203857 13 P11274,P30511,Q96FV9,P04439 4 +Positive regulation of cell cycle checkpoint 0.3542922333887094 0.159817204917376 0.8730250707214622 1.0 0.9924898322539856 6 Q9Y6D9 1 +Regulation of hydrolase activity 0.2700129039163787 0.1595625000355934 0.8732257210569718 1.0 0.9925457146712048 188 Q14108,P84095,Q86VI3,Q96N67,O00291,P05067,Q06481,Q15392,O95831,O75116,Q15375,Q92542,P23396,P07602,P50897,Q13464,Q01664,P61201,Q9Y4G8,Q96F07,Q9BXK5,P11274,Q9NRA0,Q15555,Q96K76,P49354,Q96RK4,Q9Y5X1,Q9NWH9,Q96A26,Q99523,P31751,Q96HY6,Q99538 34 +Cellular response to estrogen stimulus 0.3724573941726278 0.1587463789522563 0.8738686963396662 1.0 0.9927684780411248 5 Q8IZL8,Q969T9,Q9H6U6,Q9H7N4 4 +Positive regulation of cell differentiation 0.2565588620029354 0.1564762764751228 0.8756576175229167 1.0 0.993987380480876 136 Q8WUJ1,Q9Y4G8,P12956,Q13573,P00813,Q9UQB8,P32929,P07196,Q14185 9 +Regulation of oxidative stress induced intrinsic apoptotic signaling pathway 0.3129039378293826 0.1564348460435015 0.8756902721038489 1.0 0.993987380480876 12 Q07820,P23246,Q15233 3 +Regulation of nuclease activity 0.3124698432331502 0.1551763416540521 0.8766822989740739 1.0 0.9941498418434408 10 P23396,P31749 2 +Sphingoid metabolic process 0.3520425419522365 0.154947635534688 0.8768625993820398 1.0 0.9941498418434408 6 P04062,Q9NRA0 2 +Regulation of ubiquitin dependent protein catabolic process 0.2638895461350534 0.154597894328216 0.8771383301217872 1.0 0.9941498418434408 64 Q9Y4X5,P46379,P48729,Q93009,Q9H2J4,Q12834,O60826,O94874,Q96HY6 9 +Regulation of substrate adhesion dependent cell spreading 0.2874332927204927 0.1545146932651393 0.8772039267928198 1.0 0.9941498418434408 20 Q14185 1 +Cytoskeleton dependent cytokinesis 0.2622564081088244 0.15423175166143 0.8774270075012571 1.0 0.9941498418434408 51 Q13432,P35580,Q9HD42,Q9NZZ3,Q9Y5X1,Q13464,Q02241,O75116,Q01082,O75935,Q9NVA2,Q96RK4,O95239,Q6DKK2 14 +Astral microtubule organization 0.3882934872217849 0.15396397586628 0.8776381399411417 1.0 0.9941498418434408 4 Q7Z460,Q14980,P15311 3 +Branching involved in blood vessel morphogenesis 0.3699908759935137 0.1538277424011022 0.8777455589060561 1.0 0.9941498418434408 5 Q13043,P35222 2 +Asymmetric cell division 0.3323812863236348 0.1528840839791232 0.878489687493593 1.0 0.994795511177738 7 Q96N67 1 +Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay 0.3119335245650011 0.1526200794409553 0.8786978894053219 1.0 0.9948253991774858 11 Q9H2U1,Q9NZI8,O60506 3 +Regulation of mitotic cell cycle phase transition 0.2689419256442889 0.1511919210875814 0.8798243230749794 1.0 0.9951229782122878 94 Q13123,Q9Y619,Q9UL46,Q9Y6D9,P05067,O60566,Q06481,P12270,Q96DY7,Q01664,Q9UJX3,Q7LG56,P31350,Q96EA4,P78536,P31749,Q96K76,Q7L2J0,Q9NYL9,Q9NZM5 20 +Smooth muscle cell migration 0.3108911763320408 0.1498382056959719 0.8808922658255323 1.0 0.9959927315790804 12 P09493 1 +Negative regulation of canonical wnt signaling pathway 0.2866754536816885 0.1488079916457106 0.8817051444342596 1.0 0.9962356074894814 21 Q13043,P48729,Q16539,P50402,Q13641,P19022,P35222 7 +Mesenchymal cell differentiation 0.27205328037475 0.1485222754487997 0.8819306076410223 1.0 0.9963214036473604 37 O75116,O94788 2 +Negative regulation of defense response 0.2712975652020989 0.145668067202134 0.8841834311075614 1.0 0.9986971014527346 38 P00813,P30511,P19474 3 +Positive regulation of fatty acid metabolic process 0.3833146617165702 0.1450128713642352 0.8847007093332779 1.0 0.998773437188687 4 P31751 1 +Mitochondrial protein catabolic process 0.3545729195275945 0.1430214629919883 0.886273230431488 1.0 0.9997565702272856 2 Q96TA2 1 +Regulation of cellular component biogenesis 0.2876257800010124 0.1411717529100616 0.8877342604790848 1.0 1.0 239 Q13045,P26038,Q9HD42,P84095,Q9BQT9,Q96C92,Q9NVN8,Q13136,Q71SY5,O75027,Q9UQB8,P05067,P02786,Q14203,O75116,Q15375,Q13813,Q14457,P23396,Q9P2X3,Q13464,Q5T3I0,P45880,Q13641,Q9Y4G8,Q96F07,P09493,Q7L576,P41440,Q9BX67,Q9NRA0,Q9NUQ9,Q15555,Q9Y5X1,Q9NWH9,Q8NCA5,Q01082,O95219,O75955,Q96RK4,Q9UEY8 41 +Regulation of stress granule assembly 0.3929227757732508 0.139040129458812 0.8894184382879535 1.0 1.0 3 Q9UN86 1 +Negative regulation of small gtpase mediated signal transduction 0.3068011358070501 0.1367307222708827 0.8912436447253536 1.0 1.0 12 O94813,Q9NUQ9,Q9NWH9,O95140 4 +Regulation of axonogenesis 0.2826578539848544 0.1354483413979053 0.8922574053500159 1.0 1.0 27 Q7L576,P07196,Q8N0X7 3 +Positive regulation of protein polymerization 0.2766712563489223 0.1352479280534366 0.8924158540755993 1.0 1.0 31 P23396,Q9Y5X1,Q9NWH9,Q14203,Q9UQB8 5 +Regulation of transcription by rna polymerase iii 0.3058552938462039 0.1337568902438258 0.8935948173854886 1.0 1.0 12 O75533,O60264,Q9BUI4,Q9NY93,Q9H2U1,Q9UIG0 6 +Positive regulation of vascular associated smooth muscle cell proliferation 0.3767518549052084 0.1337513872869259 0.8935991690095744 1.0 1.0 4 P08754,P04899,O95140 3 +Positive regulation of type i interferon mediated signaling pathway 0.388952455853804 0.1327930593639768 0.8943570435711823 1.0 1.0 3 Q7Z434 1 +Hyaluronan biosynthetic process 0.3482559736336127 0.1323315440460513 0.8947220582255453 1.0 1.0 2 Q00610 1 +Regulation of hyaluronan biosynthetic process 0.3482559736336127 0.1323315440460513 0.8947220582255453 1.0 1.0 2 Q00610 1 +Hyaluronan metabolic process 0.3482559736336127 0.1323315440460513 0.8947220582255453 1.0 1.0 2 Q00610 1 +G quadruplex dna unwinding 0.3582474211289778 0.1316818877637985 0.8952359122212463 1.0 1.0 5 Q9H2U1 1 +Alternative mrna splicing via spliceosome 0.2670547787175444 0.1315686061248241 0.8953255182983233 1.0 1.0 42 Q96MU7,Q07666,Q9UNW9,Q06787,Q15287,Q9UHX1,P98175,P23246,P51114,P52756,P51116,P49756,Q9Y2W1 13 +Cell cell junction assembly 0.2738483427419088 0.1306182004255384 0.8960773442241108 1.0 1.0 32 O15228,P35221,Q13464,P35222,O75116,Q16513,O00192,Q9BX67,Q16625 9 +Organelle transport along microtubule 0.2757600166475104 0.1303415608060011 0.8962961997452399 1.0 1.0 31 O60313,Q9Y496,Q8TD16,Q9NXR1,P07196,Q5SNT2,P33176 7 +Negative regulation of developmental growth 0.3038123510396644 0.1284773583760877 0.8977712151165551 1.0 1.0 13 Q99538,Q13043,Q15375,Q8N0X7 4 +Transcription initiation from rna polymerase iii promoter 0.3854395604395623 0.1274442100560509 0.8985888269257765 1.0 1.0 3 Q9UKN8,Q12789 2 +Hypothalamus development 0.3557034784566635 0.1271625178008116 0.898811770955559 1.0 1.0 5 O75569 1 +Sphingomyelin biosynthetic process 0.3726298433635862 0.1269905202681063 0.8989479015335338 1.0 1.0 4 P22059,Q9P0L0,O15269 3 +Lipophagy 0.3726298433635803 0.1269905202680968 0.8989479015335413 1.0 1.0 4 Q9Y679,O15269,P51149 3 +Pteridine containing compound metabolic process 0.2855146052042416 0.126764690682852 0.8991266429836955 1.0 1.0 17 P41440,Q9H2D1,Q9NRN7 3 +Positive regulation of double strand break repair via nonhomologous end joining 0.3720802418247008 0.1261072508594426 0.8996470279402806 1.0 1.0 4 Q96T60,Q5UIP0,P78527 3 +Regulation of cell cycle phase transition 0.2631462503797354 0.1256017160149694 0.9000472045316739 1.0 1.0 120 Q13123,Q96FV9,O75419,Q9Y619,Q9UL46,Q9Y6D9,P05067,Q8N7H5,O60566,Q06481,P12270,Q13769,Q96DY7,Q96RU2,Q01664,Q9UJX3,Q7LG56,P31350,Q96EA4,O00213,P78536,P31749,Q96K76,Q7L2J0,Q96HY6,Q9NYL9,Q9NZM5 27 +Positive regulation of muscle cell apoptotic process 0.3135496771777892 0.1250532660964167 0.9004813810233852 1.0 1.0 8 P98175 1 +Regulation of non motile cilium assembly 0.3130978753159568 0.124028737332533 0.9012925216329128 1.0 1.0 8 Q15555 1 +Cellular response to antibiotic 0.3693529901872007 0.1217874312488456 0.903067368259496 1.0 1.0 4 Q15910,P61160 2 +Negative regulation of cell differentiation 0.2632855065347927 0.1217753448809228 0.9030769405401856 1.0 1.0 83 Q15051,Q06481,Q8N0X7,O43707,Q99523,Q9Y4G8,Q8WX92,Q96G23,P05067 9 +Regulation of protein localization to chromatin 0.3411150782751938 0.1210681274162106 0.903637074077288 1.0 1.0 2 Q7Z5K2 1 +Protein dna covalent cross linking repair 0.3411150782751927 0.1210681274162092 0.9036370740772892 1.0 1.0 2 Q9Y6I9 1 +Regulation of circadian rhythm 0.2770991888234166 0.1202127433236048 0.9043146232699206 1.0 1.0 29 P23246,Q15233,P06493,O75116,Q93009,Q13330,Q9Y2K7,Q9Y2W1 8 +Tripeptide transmembrane transport 0.3391925295248512 0.1181829359739796 0.9059227103161552 1.0 1.0 2 O15439 1 +Leukotriene transport 0.3391925295248512 0.1181829359739796 0.9059227103161552 1.0 1.0 2 O15439 1 +Sterol biosynthetic process 0.2790706300461362 0.1178977837969456 0.9061486492758636 1.0 1.0 27 Q15392 1 +Leukotriene biosynthetic process 0.378296703296705 0.1170821139968453 0.9067949832075236 1.0 1.0 3 O14880,Q99735 2 +Regulation of metal ion transport 0.2596984653549349 0.1169229480883561 0.9069211129346926 1.0 1.0 61 P21796,P33176,P22466,Q13555,O43707,P14373,O43865,Q9NRA0,P46939 9 +Brain morphogenesis 0.3325671520382494 0.1162954115104322 0.9074184220233616 1.0 1.0 6 P04062,Q96RK4 2 +Regulation of histone methylation 0.2690717556797464 0.116080359097806 0.9075888547427552 1.0 1.0 33 Q12824,Q9Y5B6,Q9BZ95,P35222,P02545,Q92541,Q13573,Q6PD62,Q8N7H5,Q96L73 10 +Embryonic brain development 0.3487319107229553 0.1152849514743448 0.9082192658136856 1.0 1.0 5 Q9Y3C6,P35222 2 +Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery 0.3484534815315727 0.1148260113611854 0.9085830313342966 1.0 1.0 5 Q5JVF3,P57740 2 +Vesicle mediated transport to the plasma membrane 0.2593460521946741 0.1147848689178917 0.9086156426317158 1.0 1.0 59 Q4J6C6,Q96C92,Q07960,P42566,Q8N2H4,Q8IWJ2,Q96L92,Q01082,O43752,O95219,Q9BZG1,O60826,Q9H223,Q567U6 14 +Response to osmotic stress 0.2794517123664924 0.114504654905517 0.908837756589726 1.0 1.0 22 Q9BPX6,P11166,Q00796 3 +Mitotic chromosome condensation 0.2995228065150427 0.1144105767794123 0.9089123299945484 1.0 1.0 12 Q9HD42,O95347,Q9NTJ3,Q15021,Q15003,Q9UIG0 6 +Regulation of autophagy of mitochondrion in response to mitochondrial depolarization 0.3312857447474545 0.1139737569008382 0.9092585968190628 1.0 1.0 6 P04062,Q16543,O95140 3 +Ribonucleoprotein complex localization 0.3139585300891053 0.1130417151330533 0.909997483255691 1.0 1.0 7 Q8WWY3 1 +Positive regulation of oligodendrocyte differentiation 0.3471687740516813 0.1127237187899392 0.9102495962235896 1.0 1.0 5 P42345,Q15382,Q92769,Q13547 4 +Regulation of protein adp ribosylation 0.3299422601044919 0.1115690444073261 0.9111651177255746 1.0 1.0 6 Q9H2P0,P23381,Q15397,Q96T60,P18887 5 +Mirna metabolic process 0.3025788374271195 0.1109511894200899 0.9116550528613026 1.0 1.0 9 Q5TAX3,Q6ZN17,Q92945,Q92841,O95453 5 +Negative regulation of oxidative stress induced cell death 0.2973125024352765 0.1093614284940366 0.912915825806033 1.0 1.0 11 P31749,Q9NWH9,Q15233 3 +Phototransduction 0.344329841456751 0.1081672548891965 0.9138630193315356 1.0 1.0 5 Q15555 1 +Positive regulation of cell substrate junction organization 0.296856727113385 0.108094927110077 0.91392039215637 1.0 1.0 11 Q13464 1 +Protein targeting 0.2555481100872305 0.1078321056918437 0.9141288747111233 1.0 1.0 132 P46379,P20645,O95831,Q99523,O43681,P55786 6 +Mitochondrial electron transport nadh to ubiquinone 0.2756422428888279 0.1066170324052339 0.9150928057008184 1.0 1.0 28 P03886,O43676,O75380 3 +Embryonic organ morphogenesis 0.2766399949339281 0.1062906267633669 0.9153517682211598 1.0 1.0 27 O15078,O75569,P54802,Q9Y366,P11274 5 +Negative regulation of actin filament bundle assembly 0.2961229250274501 0.1060664376848258 0.91552963974284 1.0 1.0 11 Q9NWH9,Q13136 2 +Regulation of endoplasmic reticulum tubular network organization 0.3419461242440955 0.1044360013964452 0.9168233538945164 1.0 1.0 5 Q6DD88,Q9H2M9,Q15041,Q15042 4 +Positive regulation of intracellular protein transport 0.2577063825975787 0.1011583189244505 0.9194247836130338 1.0 1.0 62 Q14012,Q9Y282,O15078,Q9C0E2,P31751,Q9UPN4,Q9GZY8,P55786 8 +Spliceosomal tri snrnp complex assembly 0.2929580893882832 0.1007895372342622 0.9197175326222664 1.0 1.0 10 O95400,Q8WWY3,Q9UHI6 3 +Hippo signaling 0.3234471138297775 0.1003673800337904 0.9200526659294191 1.0 1.0 6 Q13043,Q4VCS5 2 +Hematopoietic stem cell homeostasis 0.3542181918109491 0.0997120771652964 0.9205729121389592 1.0 1.0 4 Q9NX40,Q14157,P55265 3 +Gliogenesis 0.2572277122994119 0.0993708669080622 0.9208438130921316 1.0 1.0 58 Q96N66,P07942,P08670,Q8N3R9,Q92542,Q96G23,P05067 7 +Response to endogenous stimulus 0.3042143321509811 0.0973141944175779 0.9224768839872302 1.0 1.0 313 Q9BSK2,P42785,Q8WUH2,O15118,Q92896,Q9P1Z2,Q8N3R9,Q9UQB8,P05067,Q00796,P16278,P11166,P22466,Q06481,Q15392,O95831,O75116,O43865,O75592,Q92542,Q14457,O15173,P43490,Q16739,Q13464,Q01664,Q9Y4G8,Q9Y448,Q13573,P78536,Q7L576,P49354,P08670,Q99523,P25705,P31751,Q9NS86,O75844,P07196 39 +Regulation of multicellular organismal development 0.2688068660098904 0.0962538127511345 0.9233189927806648 1.0 1.0 196 P46379,Q92896,Q9BQT9,Q9UQB8,Q96G23,P22466,Q06481,O75116,Q9H2J4,P00813,Q13049,Q96TA1,Q13464,Q13641,Q9Y4G8,P12956,Q13573,Q9NZ08,P57105,O75844,P07196 21 +Focal adhesion assembly 0.2757956388769775 0.0955811392636712 0.923853245294586 1.0 1.0 25 O75116,P12814,Q13464 3 +Negative regulation of dna templated transcription elongation 0.2906831635160448 0.0950257326643745 0.9242943876915904 1.0 1.0 10 Q8IXH7,O00267,O14776,Q8WX92 4 +Negative regulation of transcription by rna polymerase i 0.3506457818082094 0.0949650182573314 0.9243426126938066 1.0 1.0 4 O75367,Q9P0M6,Q9NZM5 3 +Chromosome localization 0.2612078505183453 0.094724242875454 0.924533861525992 1.0 1.0 42 Q96DB5,Q9HD42,Q96EE3,Q8WXW3,Q9NZZ3,P02545,Q96EA4,Q9HC35,Q9NXR1,Q9Y6D9,Q14457,Q14807 12 +Regulation of b cell differentiation 0.3216149409502835 0.0946262273420045 0.9246117168993302 1.0 1.0 2 Q5JVF3 1 +Negative regulation of cellular macromolecule biosynthetic process 0.263406365789777 0.0923381891394305 0.9264293474175728 1.0 1.0 107 O60506,P27544,P51114,Q9NVN8,Q92945,Q9UKZ1,Q8IZD4,Q9NZI8,P12270,Q10713,O75116,Q13868,Q9BXS4,Q9Y6M1,P51116,Q14103,P23396,Q96TA1,Q13464,Q29RF7,Q9BZE4,Q5TAX3,Q99543,Q9BPZ3,Q9HCE1,Q9NQT5,Q9H2U1,Q9NQX7,O75175 29 +Negative regulation of mitotic cell cycle 0.2550137128988564 0.0911036862617623 0.9274102036129646 1.0 1.0 54 Q13123,O60566,Q96K76,Q96DY7,P12270,Q96EA4,Q6ZVM7,Q9NZM5,Q9Y619,Q9Y6D9,P35222 11 +Positive regulation of transcription regulatory region dna binding 0.2974077683586018 0.0909765742374354 0.9275112049013444 1.0 1.0 8 Q96TA1,Q96HY6 2 +Vascular associated smooth muscle cell proliferation 0.2883581340487244 0.0892618396635273 0.9288738205059136 1.0 1.0 10 P09601,P09493,Q53EL6,O95140 4 +Lipoprotein biosynthetic process 0.2754913091373597 0.0881344586650617 0.9297698088778938 1.0 1.0 17 Q16739,Q5MNZ6,P04062,Q969N2,Q5H8A4 5 +Mononuclear cell differentiation 0.253821439194895 0.0876048352026092 0.9301907590220286 1.0 1.0 49 P35579,P00813,P12956,P78536 4 +Pallium development 0.2579088648661521 0.0874394198683703 0.930322236829532 1.0 1.0 45 P11166,P07942,Q9NZI8,Q96N66,O94813,Q9Y6A5,Q8N3R9,Q9NXR1,Q96RK4,P07196,P19022,Q9HCS7,P35222 13 +Regulation of calcineurin mediated signaling 0.314105825881198 0.0854827373559203 0.9318776188277188 1.0 1.0 6 P42345,Q9UHD1,Q8IWX8 3 +Negative regulation of lipid biosynthetic process 0.2866052368956642 0.0850013486517546 0.9322603185226744 1.0 1.0 10 P49748 1 +Mitochondrial membrane organization 0.2536376261874507 0.0841896591370128 0.9329056398124728 1.0 1.0 53 O60313,Q16891,P45880,Q15070,Q9Y4W6,Q13505,O75431,Q9NX63 8 +Heart development 0.2627017529301926 0.0838376909200535 0.9331854804731636 1.0 1.0 98 Q9Y366,P09493,O94788,O75844,P02545,O75116,P10253,P42892,Q9BQ70,O96028,O75592,Q8NDZ4 12 +Roof of mouth development 0.3123453395655843 0.0828381121205277 0.9339802641657822 1.0 1.0 6 Q9NWT1,Q12797,Q9P2D1,O95747,O95470 5 +Regulation of chromosome condensation 0.29009823894665 0.0827860119064227 0.9340216918263208 1.0 1.0 9 O95347,Q9NTJ3,Q15021,O60264,Q15003,Q9UIG0 6 +Cellular response to insulin stimulus 0.2545386791410771 0.0826671080803288 0.9341162392727558 1.0 1.0 56 Q9UQB8,Q06481 2 +Mitochondrial protein processing 0.3120455147730668 0.082392750608664 0.9343344006271584 1.0 1.0 6 Q9Y4W6 1 +Blastocyst development 0.2606215460124115 0.0815178522368922 0.9350301280940034 1.0 1.0 37 Q12824,O75175,Q8IWS0,P49321,P17655,P61201,O95140,P31350,Q92541,Q9BRT9,P00813,Q6PD62,Q9HCS7 13 +Mitochondrial adp transmembrane transport 0.3489010989011006 0.0814912080060933 0.9350513166198168 1.0 1.0 3 P12236,P05141 2 +Positive regulation of monocyte chemotaxis 0.3393714993381754 0.0811176706818541 0.9353483728256896 1.0 1.0 4 Q99538,Q8NHP6 2 +Regulation of transcription of nucleolar large rrna by rna polymerase i 0.2848885218827452 0.0808998356901505 0.935521610638962 1.0 1.0 10 Q12824,P42345,P51532,O75367,Q9P0M6,Q9H8H0,P19338,Q13610,Q9NZM5 9 +Negative regulation of striated muscle cell differentiation 0.2959295929593069 0.0801425557671249 0.9361238769692836 1.0 1.0 7 P11413,O94826,Q15910,P25490,Q13547,P67809 6 +Long chain fatty acyl coa biosynthetic process 0.2914873783589722 0.0797848969358339 0.9364083365266508 1.0 1.0 8 Q9UKU0,Q6Y1H2 2 +Error free translesion synthesis 0.3078824498764021 0.0796065947170332 0.9365501500401228 1.0 1.0 2 P28340 1 +Positive regulation of pathway restricted smad protein phosphorylation 0.3467032967032985 0.0792687995461846 0.9368188225431826 1.0 1.0 3 P33981,P67870 2 +Microtubule based process 0.2839761217456821 0.0791119386244528 0.9369435876286571 1.0 1.0 241 O15344,Q9Y496,Q9HD42,Q8TD16,Q8WVM7,Q96N67,Q9H6D7,P02545,Q12834,Q9Y366,P05067,Q00796,P35579,Q9UH99,Q96CW5,Q9H3R5,Q08379,Q86UP2,P53985,Q14203,O75116,O75935,Q96ED9,O43805,P29372,Q5SNT2,P33176,P23396,Q8WXW3,Q8IWJ2,Q13464,P52732,Q14168,Q96EA4,Q9Y448,Q9UQE7,Q15555,O94927,Q9NWH9,Q96CS2,O95684,O43663,Q9BSJ2,Q9UPN4,P07196,P23246,A0AVF1 47 +Protein localization to basolateral plasma membrane 0.3464285714285733 0.0789951135260876 0.9370365097602172 1.0 1.0 3 Q5EBL8,P61026 2 +Establishment of epithelial cell apical basal polarity 0.3093433700628506 0.0784449045612998 0.937474154881662 1.0 1.0 6 P15311,P26038 2 +Spliceosomal conformational changes to generate catalytic conformation 0.3369057433360922 0.0783146191898747 0.9375777887470635 1.0 1.0 4 O75643,Q9HCS7,Q9ULR0 3 +Regulation of protein deacetylation 0.2727497717804357 0.0781414446323074 0.937715539914454 1.0 1.0 17 Q9NRA0 1 +Regulation of nucleotide binding oligomerization domain containing signaling pathway 0.3034880527327602 0.0753893924876366 0.9399048987607292 1.0 1.0 2 Q96RT1 1 +Nucleotide binding oligomerization domain containing 2 signaling pathway 0.3034880527327602 0.0753893924876366 0.9399048987607292 1.0 1.0 2 Q96RT1 1 +Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway 0.3034880527327602 0.0753893924876366 0.9399048987607292 1.0 1.0 2 Q96RT1 1 +Regulation of protein targeting 0.2678722265057618 0.0753752090087644 0.9399161834314264 1.0 1.0 29 P55786 1 +Dorsal ventral pattern formation 0.3068864938260534 0.0749579674984086 0.9402481548404542 1.0 1.0 6 Q9Y366 1 +Mitotic nuclear division 0.2515822216747505 0.0740855273004929 0.9409423311531078 1.0 1.0 134 Q13123,Q86XL3,Q6NUK4,Q96EE3,Q9HD42,Q8N3U4,Q16763,Q02241,Q8WVM7,O95347,Q9NTJ3,Q12834,P50748,Q9Y6D9,Q14683,Q9NTI5,Q14807,O60566,Q96JM3,Q8IY18,Q08379,P12270,Q9NXR1,Q15021,Q96DY7,Q14457,Q96DB5,P30260,Q9NZZ3,Q8WXW3,Q9UJX3,P52732,Q96EA4,Q9Y448,Q29RF7,Q15003,O95239,Q9UQE7,P83731,Q86XI2,Q96IY1,Q9Y6A5,Q9HC35,O43663,Q6ZVM7,Q9BS16,Q9UIG0 47 +Glandular epithelial cell development 0.2856356631810622 0.0735407475372686 0.9413758199941048 1.0 1.0 9 P49841,P49840,P26367,Q00534,P49327,P19022,Q15382,P31749 8 +Transcription coupled nucleotide excision repair 0.3317001126987318 0.0726565736897288 0.9420794063432828 1.0 1.0 4 Q93009 1 +Nucleolar large rrna transcription by rna polymerase i 0.2851239669421492 0.07238399946425 0.9422963179682524 1.0 1.0 13 Q12824,P42345,O15160,P51532,Q9GZS1,Q9P0M6,O75367,Q9H8H0,P19338,Q13610,Q9NZM5,Q13428 12 +Phenol containing compound catabolic process 0.2990936555891182 0.0714442188218476 0.9430442179689156 1.0 1.0 2 P16930 1 +Positive regulation of protein localization 0.2457655349853308 0.0713376847141099 0.9431290035511236 1.0 1.0 148 Q14012,P78371,Q9NVN8,P84095,Q9BQT9,Q96C92,P55786,O95563,P02786,Q7Z434,Q9C0E2,O75116,Q96D46,P33176,Q9Y282,O15078,P35580,Q01082,P31751,Q96HY6,Q9UPN4,Q9GZY8 22 +Positive regulation of histone h3 k4 methylation 0.2840184002357261 0.0712921293416286 0.9431652591674682 1.0 1.0 12 Q92541,P35222,Q13573 3 +Estrogen biosynthetic process 0.3365384615384637 0.0697393097871493 0.9444011532478396 1.0 1.0 3 Q53GQ0,P56937 2 +Negative regulation of cell death 0.2829470434172755 0.06914696473016 0.9448726380128344 1.0 1.0 240 Q86XL3,Q01105,P46379,Q9HCL2,O15118,Q9HD42,Q07820,P30511,P14174,P02545,Q9UMX5,O60313,P21796,P02786,Q15392,P00813,P32929,Q13049,Q14457,Q8NDZ4,Q9P2X3,P50897,Q96TA1,Q8N2F6,Q13464,Q7LG56,P45880,P30533,Q9H300,Q6N069,Q96K76,Q9NWH9,P31751,Q96HY6,Q99538,P07196 36 +Cellular response to arsenic containing substance 0.2831315809353046 0.068543510254329 0.9453529853219892 1.0 1.0 9 P09601,Q9H2U1 2 +Positive regulation of plasma membrane bounded cell projection assembly 0.2654228198665082 0.0640898773941248 0.9488986619456234 1.0 1.0 29 Q15555,Q96C92,Q8NCA5,Q96RK4,Q7L576,Q16625 6 +Protein k11 linked ubiquitination 0.280598147121682 0.0636268245542232 0.949267372107635 1.0 1.0 9 Q9UJX3,Q16763 2 +Negative regulation of b cell activation 0.3217917010167859 0.0628362979526369 0.949896861381327 1.0 1.0 4 Q16512,Q96IZ0,Q96FV9 3 +Regulation of mitotic cell cycle spindle assembly checkpoint 0.2976259575736191 0.0626810530078391 0.9500204852303012 1.0 1.0 6 Q9Y6D9 1 +Positive regulation of transcription of nucleolar large rrna by rna polymerase i 0.2846534653465434 0.062603766261674 0.9500820302597192 1.0 1.0 7 Q12824,P42345,P51532,Q9H8H0,P19338,Q13610 6 +Detection of light stimulus 0.2975107642232538 0.0625368493906994 0.9501353177842684 1.0 1.0 6 Q13432,Q15555 2 +Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors 0.2878330129085357 0.0625153756215659 0.950152417913826 1.0 1.0 2 Q13043 1 +Positive regulation of cellular protein catabolic process 0.2509848704644153 0.0623518920497144 0.9502826049523412 1.0 1.0 54 P48729,Q9Y4X5,P46379,Q6ZXV5,Q12834,Q96HY6,O60826 7 +Cellular response to vascular endothelial growth factor stimulus 0.2955732746769369 0.0601423340588295 0.9520422732634086 1.0 1.0 6 O14786,Q16539,O00159,P04083,P31749 5 +Actin polymerization or depolymerization 0.2509946869575651 0.0595801889431468 0.9524899972666796 1.0 1.0 55 Q9NUQ9,Q9Y5X1,Q96F07,Q01082,Q96RK4,Q7L576,Q9UQB8,Q13813,Q9UEY8 9 +Calcium ion transport 0.2511448626428113 0.0589236441988226 0.9530129254207598 1.0 1.0 69 P21796,Q9NWR8,Q9HC07,Q13555,P16615,Q9H4I9,P14373,Q9BPX6,O75844,Q8IYU8,Q9NRA0,O14936 12 +Response to ionizing radiation 0.2561370507393446 0.0582657659942515 0.9535369359480708 1.0 1.0 39 O60858,P12956,Q70UQ0 3 +Response to endoplasmic reticulum stress 0.2598833390902654 0.0582602888668365 0.95354129865241 1.0 1.0 96 P46379,Q8IXB1,P16615,O95831,O60858,P41440,P32929 7 +Positive regulation of embryonic development 0.2786333468072512 0.0578817812503297 0.9538427952449452 1.0 1.0 8 Q96TA1 1 +Sodium ion transmembrane transport 0.2641815655960607 0.0575192969550927 0.9541315348079268 1.0 1.0 20 P55011,O43707,Q6P4Q7,Q9Y6M7,P46939 5 +Ovulation cycle 0.2781666369812955 0.057147544908591 0.9544276629199008 1.0 1.0 8 O75592,O95470 2 +Regulation of cellular response to stress 0.2558104017786121 0.0569334423954657 0.954598214328862 1.0 1.0 172 P46379,O15344,P51114,Q07820,P14174,Q96G23,P05067,O60313,O75116,Q9BPX6,Q13049,P29372,O94874,P23396,Q15233,O96028,P31749,Q96HY6,Q96K76,Q9UNS2,Q9NWH9,Q7Z4V5,P10586,O75844,P23246 25 +Regulation of nucleobase containing compound transport 0.2765136825664891 0.0567677262732027 0.9547302231661308 1.0 1.0 11 Q9H7Z3,Q07666 2 +Positive regulation of protein localization to centrosome 0.3195054945054966 0.0563870163560597 0.9550334999463644 1.0 1.0 3 Q9BV73,P49841 2 +Regulation of cell cycle checkpoint 0.2790482945369293 0.0561431841555722 0.9552277421883066 1.0 1.0 13 P12270,Q9Y6D9,Q96FV9 3 +Embryo development ending in birth or egg hatching 0.2459026545499686 0.05586288445443 0.9554510385501728 1.0 1.0 140 P35579,Q9Y366,P23786,O94788,Q9UNS2,P49321,P17655,O43772,O75787,P61201,P31350,Q92541,P42892,Q9BRT9,Q96RK4,P00813,Q96EK5,Q9UPT9 18 +Trabecula morphogenesis 0.3164835164835184 0.0543388268411366 0.9566652158880152 1.0 1.0 3 Q9P2D1,Q15648 2 +Heart trabecula morphogenesis 0.3164835164835184 0.0543388268411366 0.9566652158880152 1.0 1.0 3 Q9P2D1,Q15648 2 +Layer formation in cerebral cortex 0.3116401508648382 0.0540119658610225 0.9569256307804652 1.0 1.0 4 Q96N66 1 +Positive regulation of cellular amide metabolic process 0.2499165426314033 0.05179884927032 0.9586889724715048 1.0 1.0 70 Q9P2X3,P51114,P08670,O75116,Q567V2,Q9H2U1,Q9Y2R0,Q9NRA0,Q9NWS8 9 +Regulation of protein localization to centrosome 0.307502061005789 0.050757442958265 0.9595188027365946 1.0 1.0 4 Q9BV73,P49841,P37198 3 +Negative regulation of fibroblast apoptotic process 0.3106972555839843 0.0506701135645268 0.9595883919661496 1.0 1.0 3 Q9UEE9 1 +Negative regulation of double strand break repair via homologous recombination 0.2976910390324393 0.0502693355190508 0.9599077595742012 1.0 1.0 5 A6NHR9,Q6NSI4,Q5UIP0,Q9NRR5 4 +Actin filament organization 0.2568641436280784 0.0498109011757899 0.9602730795860824 1.0 1.0 119 Q13045,P84095,Q13136,P14373,P06753,O00291,Q9UQB8,P35221,Q96JJ3,O75116,P67936,Q13813,P12814,Q13464,Q96F07,P09493,Q7L576,Q9NUQ9,Q9Y5X1,Q9NWH9,Q6WCQ1,Q01082,Q96RK4,Q9UEY8 24 +Ribonucleoprotein complex disassembly 0.2962126957784188 0.0489271025234568 0.9609773900322008 1.0 1.0 5 Q07866,P33176 2 +Response to platelet derived growth factor 0.284575199340122 0.0476352859930913 0.9620069097828896 1.0 1.0 6 P46940,P35241,Q13547,Q96A49,Q9BR76 5 +Cellular response to interferon beta 0.2841047925642357 0.0471406360813538 0.96240114041199 1.0 1.0 6 P60604,P17655 2 +Response to interferon beta 0.2841047925642357 0.0471406360813538 0.96240114041199 1.0 1.0 6 P60604,P17655 2 +Pyramidal neuron differentiation 0.3005494505494528 0.0449973628827164 0.9641094109416736 1.0 1.0 3 Q02218,P04062 2 +Regulation of chromosome segregation 0.2530416822230941 0.04419080079421 0.9647523147944684 1.0 1.0 41 O60566,Q8IY18,P12270,Q9UJX3,Q96EA4,Q9Y6A5,Q9Y6D9,Q14457 8 +L serine transport 0.2983152082701644 0.0438716993932343 0.965006674185252 1.0 1.0 3 Q15758 1 +Response to electrical stimulus 0.2802104663997127 0.0431692052193041 0.9655666528698476 1.0 1.0 6 Q7L576,Q02952 2 +Metencephalon development 0.2565813844819554 0.042653018657671 0.9659781311383172 1.0 1.0 32 Q5KU26,Q92542,Q9BRK5,P54802 4 +Regulation of erbb signaling pathway 0.2718499117506813 0.0425667013144549 0.9660469399207978 1.0 1.0 14 P78536,O00291 2 +Negative regulation of cell growth involved in cardiac muscle cell development 0.2956856279197742 0.042492997783471 0.9661056936696568 1.0 1.0 4 P11413,P25490,O94826 3 +Negative regulation of cardiac muscle tissue growth 0.2956856279197742 0.042492997783471 0.9661056936696568 1.0 1.0 4 P11413,P25490,O94826 3 +Regulation of vesicle fusion 0.2854738065064318 0.0399981250656314 0.9680946210792734 1.0 1.0 5 P31751 1 +Regulation of oligodendrocyte differentiation 0.2665397918624897 0.0391417280349503 0.9687773922833912 1.0 1.0 7 Q15382,P35222 2 +Cell substrate junction organization 0.2555648425400589 0.0379218002041926 0.9697500314993224 1.0 1.0 32 O75116,P11274,P12814,Q13464 4 +Rrna transcription 0.2604252968793191 0.0376395242760532 0.9699750944212115 1.0 1.0 22 Q9Y5Q9,O75367,Q9P0M6,Q9H9Y6,Q9UKN8,Q12824,Q9H2V7,P51532,Q9GZS1,P56192,Q13610,P04637,Q9Y5Q8,Q9H8H0,P19338,Q13428,P42345,O15160,Q9BYG3,Q12789,Q9NZM5 21 +Regulation of actin nucleation 0.264353497719461 0.0373025634732678 0.9702437615608948 1.0 1.0 10 Q7L576,P14373 2 +Negative regulation of organelle organization 0.2549537418778118 0.0362531575355459 0.9710805002358712 1.0 1.0 121 Q13045,Q13123,O15344,Q9NVN8,Q92878,Q13136,P02545,Q9Y6D9,O60313,O60566,P02786,P12270,Q9Y6W5,Q96DY7,Q13813,Q14457,P29372,Q9H3K2,Q9UHB6,Q96EA4,Q9H300,P31749,Q15691,Q9NUQ9,Q6ZVM7,Q9NWH9,Q01082,Q96RK4,Q9NYL9,Q9UEY8,Q9UIG0 31 +Gamete generation 0.255890980050488 0.0356911916838809 0.9715285940967796 1.0 1.0 118 Q07666,Q8NB78,P46379,P54619,Q15102,P14373,P11717,Q9BY67,O95714,Q00536,O75718,Q9UHI6,Q9Y2W6,Q96MU7,Q8N2A8,Q9BTX1,O95470,O15287,Q9BX67,P35222,P31749,Q96PU8,Q9BPZ3,Q9UJC3,Q9H2U1,Q96RK4,Q9UPN4,P26583,Q9P0K7,A0AVF1 30 +Positive regulation of mrna 3 end processing 0.2794158975228037 0.0355714224207289 0.9716240954995892 1.0 1.0 5 Q9H2U1 1 +Regulation of dna damage checkpoint 0.2627407821753381 0.0349258227672626 0.9721388895803418 1.0 1.0 7 Q96FV9 1 +Positive regulation of programmed necrotic cell death 0.271703296703299 0.0334587005509277 0.9733087995636096 1.0 1.0 3 Q9NZI8,P04637 2 +Interleukin 6 mediated signaling pathway 0.2717032967032992 0.0334587005509277 0.9733087995636096 1.0 1.0 3 Q6PD62,P40763 2 +Regulation of vesicle size 0.2791975817532437 0.0332964748513766 0.9734381648638608 1.0 1.0 4 Q12768,P20339,Q96CW1 3 +Developmental pigmentation 0.2596724445338415 0.0313886249390791 0.9749596126664186 1.0 1.0 8 O75787 1 +Cell projection assembly 0.2551245469415767 0.030688202036831 0.9755182001430576 1.0 1.0 119 Q92538,Q9Y496,P51114,P84095,Q96C92,Q9Y366,Q16625,Q9NR77,A6NIH7,Q14203,O15078,Q8WXW3,Q13464,Q9Y4G8,Q7L576,Q9H223,Q15051,Q15555,Q8NCA5,Q96RK4,Q9UPN4,A0AVF1 22 +Response to interleukin 6 0.2718526663001719 0.0306242961265443 0.975569165727712 1.0 1.0 5 Q6PD62,Q96JM3,P35232,P40763 4 +Negative regulation of metaphase anaphase transition of cell cycle 0.2555565741113457 0.0303664492832783 0.9757748021026034 1.0 1.0 19 Q13123,O60566,P12270,Q96EA4,Q9Y6D9 5 +Protein processing involved in protein targeting to mitochondrion 0.2565934065934089 0.0296091375961555 0.9763787777620676 1.0 1.0 3 O75439,Q10713 2 +Transport of virus 0.2639218541561479 0.0288487144976768 0.9769852484789772 1.0 1.0 6 Q06787,P52292,P42566 3 +Negative regulation of peptidyl tyrosine phosphorylation 0.2600036746895819 0.0287798692820538 0.9770401562149228 1.0 1.0 9 O95684 1 +Response to monosaccharide 0.2502012705372134 0.0273005339442718 0.9782200310024688 1.0 1.0 40 Q9HCL2 1 +Regulation of deoxyribonuclease activity 0.2550152388736536 0.0258945938196254 0.979341412109308 1.0 1.0 8 P23396 1 +Trna transcription 0.2592796260654439 0.025405878226389 0.9797312224759368 1.0 1.0 6 Q9Y5Q9,P62875,Q12789,Q9UKN8,Q9Y5Q8 5 +Mrna 3 splice site recognition 0.2614479382814835 0.0247973658561499 0.9802165921559942 1.0 1.0 5 Q12874,Q15428 2 +Formation of primary germ layer 0.253804304743973 0.0244664619895121 0.980480535157719 1.0 1.0 19 P07942,P17301,Q8N7H5,Q5T9L3,Q92541,Q6PD62,P35222 7 +5s class rrna transcription by rna polymerase iii 0.2592083562396973 0.0236817903079733 0.9811064311621288 1.0 1.0 5 Q9Y5Q9,Q9UKN8,Q12789,Q9Y5Q8 4 +Trna aminoacylation for mitochondrial protein translation 0.2525447042641044 0.0231352509448662 0.9815423870171028 1.0 1.0 8 Q9NP81,P41250,Q5JTZ9,Q9Y2Z4,Q5JPH6,Q9BW92,Q9UGM6 7 +Peptidyl arginine n methylation 0.2559098405717482 0.0221231825011462 0.9823496940384376 1.0 1.0 5 O60678,Q7L592,O14744,Q86X55 4 +Peptidyl arginine methylation 0.2559098405717482 0.0221231825011462 0.9823496940384376 1.0 1.0 5 O60678,Q7L592,O14744,Q86X55 4 +Histone serine phosphorylation 0.2553600879604225 0.0218729704029832 0.9825492861092892 1.0 1.0 5 Q13043,Q96GD4,P54646,O14965 4 +Regulation of proteasomal ubiquitin dependent protein catabolic process 0.2456729083532795 0.0202472652727554 0.983846123366264 1.0 1.0 56 P48729,Q9Y4X5,P46379,Q93009,Q12834,Q96HY6,O94874 7 +Protein targeting to mitochondrion 0.2430390512880734 0.0201876329796374 0.9838936933292696 1.0 1.0 51 O95831,P55786 2 +Regulation of stem cell proliferation 0.250481165795993 0.0195963944343168 0.9843653401067548 1.0 1.0 6 P19525,O60341,Q96AC1,Q00839,P26583 5 +Mirna catabolic process 0.2486853744121769 0.0190440346400014 0.9848059772069148 1.0 1.0 5 Q6ZN17 1 +Acetyl coa biosynthetic process 0.2578311364540583 0.0186838008273187 0.9850933510676116 1.0 1.0 11 P11177,O95563 2 +Negative regulation of cytoskeleton organization 0.2442961095776197 0.0170825010511657 0.9863707990149742 1.0 1.0 54 Q13045,Q15691,Q9NUQ9,O15344,Q9UHB6,Q9NWH9,Q13136,Q9NYL9,Q01082,Q96RK4,Q9Y6W5,Q13813,P29372,Q9UEY8 14 +Histone deubiquitination 0.2553747562340692 0.014314872649406 0.9885787741890284 1.0 1.0 11 Q9UPT9 1 +Dna dealkylation 0.2434066216265569 0.0138313025896422 0.9889645690644464 1.0 1.0 8 P29372 1 +Negative regulation of ion transport 0.2523909869026105 0.0124882703400931 0.9900360608960164 1.0 1.0 21 P14373,P21796 2 +Negative regulation of amyloid precursor protein catabolic process 0.2497817907280284 0.0124077715403746 0.9901002846694243 1.0 1.0 10 Q13464 1 +Positive regulation of organelle assembly 0.2533346463363019 0.012379537801925 0.9901228102033688 1.0 1.0 29 Q15555,Q96C92,O95219,Q96RK4,Q14457 5 +Negative regulation of protein dephosphorylation 0.2577233244380566 0.0123507181871239 0.990145803171228 1.0 1.0 12 O75116 1 +Regulation of mrna export from nucleus 0.2270478284771913 0.0122204178714373 0.990249759935646 1.0 1.0 5 Q7KZ85,P12270,Q96ST2,Q08J23 4 +Ribonucleoside monophosphate metabolic process 0.2497877117390896 0.012027394832125 0.9904037587198656 1.0 1.0 32 P00813,P55263 2 +Positive regulation of mrna processing 0.252109253003863 0.0115540888336709 0.990781376015652 1.0 1.0 21 Q13573,Q9H2U1,Q8N7H5,Q96E39 4 +Dna modification 0.2456400501662681 0.0082443260792561 0.993422054023194 1.0 1.0 34 Q8NB78,Q8N2A8,Q96TA1,Q9NQT5,Q93009,O75844,Q9Y2W6,P29372 8 +Stress activated protein kinase signaling cascade 0.2462931241485765 0.0081715150131342 0.9934801468918052 1.0 1.0 36 O75844,P05067 2 +Protein sumoylation 0.2571915956751732 0.0071282647139644 0.99431251580501 1.0 1.0 14 Q9NVN8,P14373,P35222,P49792 4 +Negative regulation of small molecule metabolic process 0.2524534836716554 0.0069530292837855 0.9944523299836896 1.0 1.0 23 Q8WXW3,P31749,P49748,Q06481 4 +Telomere organization 0.2446780481186698 0.005180572628315 0.995866519573045 1.0 1.0 68 Q9UQ84,P41440,P12956 3 +Regulation of cyclin dependent protein kinase activity 0.2500634935326716 0.0048654924088705 0.9961179140430454 1.0 1.0 21 P78536,Q9BZE4,Q01664,O00410 4 +T cell differentiation 0.2526964647887153 0.0040348097087423 0.9967806963624966 1.0 1.0 26 P00813 1 +Regulation of rig i signaling pathway 0.2222222222222303 0.003256988956312 0.9974013033915397 1.0 1.0 7 Q92890,Q9Y4E8,Q8TAT6,Q07021,Q9NZM5,Q9NUD5 6 +Regulation of amyloid precursor protein catabolic process 0.2539273020380688 0.0026922676724033 0.9978518837856748 1.0 1.0 15 O75116,Q13464 2 +Positive regulation of protein catabolic process 0.2458850429338331 0.0017515809238767 0.9986024413384686 1.0 1.0 75 Q9Y4X5,P46379,Q9Y5X1,Q6ZXV5,Q12834,Q96HY6,O60826,Q13049 8 +Protein import into mitochondrial matrix 0.2372496472811612 0.0003605455779879 0.9997123262560904 1.0 1.0 9 O96008 1 diff --git a/msigdb_gobp/selections.json b/msigdb_gobp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..45bcca42c36fe72cece1853ca36165f64bf16292 --- /dev/null +++ b/msigdb_gobp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["10 formyltetrahydrofolate metabolic process", "2 oxoglutarate metabolic process", "2fe 2s cluster assembly", "3 phosphoadenosine 5 phosphosulfate biosynthetic process", "3 phosphoadenosine 5 phosphosulfate metabolic process", "3 utr mediated mrna destabilization", "3 utr mediated mrna stabilization", "5 phosphoribose 1 diphosphate metabolic process", "5s class rrna transcription by rna polymerase iii", "Abscission", "Acetyl coa biosynthetic process", "Acetyl coa biosynthetic process from pyruvate", "Acetyl coa metabolic process", "Acid secretion", "Acidic amino acid transport", "Acrosome assembly", "Acrosome reaction", "Actin crosslink formation", "Actin cytoskeleton reorganization", "Actin filament based movement", "Actin filament based process", "Actin filament based transport", "Actin filament bundle organization", "Actin filament depolymerization", "Actin filament network formation", "Actin filament organization", "Actin filament polymerization", "Actin filament reorganization", "Actin filament severing", "Actin mediated cell contraction", "Actin modification", "Actin myosin filament sliding", "Actin nucleation", "Actin polymerization dependent cell motility", "Actin polymerization or depolymerization", "Action potential", "Activated t cell proliferation", "Activation induced cell death of t cells", "Activation of adenylate cyclase activity", "Activation of cysteine type endopeptidase activity", "Activation of cysteine type endopeptidase activity involved in apoptotic process", "Activation of cysteine type endopeptidase activity involved in apoptotic process by cytochrome c", "Activation of gtpase activity", "Activation of immune response", "Activation of innate immune response", "Activation of janus kinase activity", "Activation of nf kappab inducing kinase activity", "Activation of phospholipase c activity", "Activation of phospholipase d activity", "Activation of protein kinase activity", "Activation of protein kinase b activity", "Activation of protein kinase c activity", "Activin receptor signaling pathway", "Actomyosin contractile ring organization", "Actomyosin structure organization", "Acute inflammatory response", "Acute inflammatory response to antigenic stimulus", "Acute phase response", "Acyl carnitine transmembrane transport", "Acylglycerol homeostasis", "Adaptation of signaling pathway", "Adaptive immune response", "Adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains", "Adaptive thermogenesis", "Adenosine metabolic process", "Adenosine to inosine editing", "Adenylate cyclase activating adrenergic receptor signaling pathway", "Adenylate cyclase activating adrenergic receptor signaling pathway involved in heart process", "Adenylate cyclase activating dopamine receptor signaling pathway", "Adenylate cyclase activating g protein coupled receptor signaling pathway", "Adenylate cyclase inhibiting dopamine receptor signaling pathway", "Adenylate cyclase inhibiting g protein coupled receptor signaling pathway", "Adenylate cyclase modulating g protein coupled receptor signaling pathway", "Adherens junction assembly", "Adherens junction maintenance", "Adherens junction organization", "Adhesion of symbiont to host", "Adhesion of symbiont to host cell", "Adiponectin activated signaling pathway", "Adipose tissue development", "Adp biosynthetic process", "Adp metabolic process", "Adp transport", "Adrenal gland development", "Adrenergic receptor signaling pathway", "Adult behavior", "Adult heart development", "Adult locomotory behavior", "Aerobic respiration", "Aggrephagy", "Aggresome assembly", "Aging", "Alanine catabolic process", "Alanine transport", "Alcohol biosynthetic process", "Alcohol catabolic process", "Alcohol metabolic process", "Aldehyde biosynthetic process", "Aldehyde catabolic process", "Alditol biosynthetic process", "Alditol catabolic process", "Alditol metabolic process", "Alditol phosphate metabolic process", "Alkanesulfonate metabolic process", "Allantoin metabolic process", "Alpha amino acid catabolic process", "Alpha amino acid metabolic process", "Alpha beta t cell activation", "Alpha beta t cell differentiation", "Alpha beta t cell proliferation", "Alpha ketoglutarate transport", "Alpha linolenic acid metabolic process", "Alternative mrna splicing via spliceosome", "Ameboidal type cell migration", "Amelogenesis", "Amide biosynthetic process", "Amide transport", "Amine biosynthetic process", "Amine catabolic process", "Amine metabolic process", "Amine transport", "Amino acid activation", "Amino acid betaine biosynthetic process", "Amino acid betaine metabolic process", "Amino acid betaine transport", "Amino acid homeostasis", "Amino acid import", "Amino acid import across plasma membrane", "Amino acid neurotransmitter reuptake", "Amino acid salvage", "Amino acid transmembrane transport", "Amino acid transport", "Amino sugar biosynthetic process", "Amino sugar catabolic process", "Amino sugar metabolic process", "Aminoacyl trna metabolism involved in translational fidelity", "Aminoglycan biosynthetic process", "Aminoglycan catabolic process", "Aminoglycan metabolic process", "Aminoglycoside antibiotic metabolic process", "Aminophospholipid translocation", "Aminophospholipid transport", "Ammonium ion metabolic process", "Ammonium transmembrane transport", "Amp biosynthetic process", "Amp catabolic process", "Amp metabolic process", "Amp salvage", "Ampa glutamate receptor clustering", "Amygdala development", "Amyloid beta clearance", "Amyloid beta clearance by cellular catabolic process", "Amyloid beta clearance by transcytosis", "Amyloid beta formation", "Amyloid beta metabolic process", "Amyloid fibril formation", "Amyloid precursor protein biosynthetic process", "Amyloid precursor protein catabolic process", "Amyloid precursor protein metabolic process", "Anagen", "Anaphase promoting complex dependent catabolic process", "Anatomical structure arrangement", "Anatomical structure formation involved in morphogenesis", "Anatomical structure homeostasis", "Anatomical structure maturation", "Androgen biosynthetic process", "Androgen catabolic process", "Androgen metabolic process", "Androgen receptor signaling pathway", "Angiogenesis involved in coronary vascular morphogenesis", "Angiogenesis involved in wound healing", "Angiotensin activated signaling pathway", "Animal organ formation", "Animal organ maturation", "Animal organ morphogenesis", "Animal organ regeneration", "Anion homeostasis", "Anion transmembrane transport", "Anion transport", "Anoikis", "Anterior head development", "Anterior posterior axis specification", "Anterior posterior pattern specification", "Anterograde axonal transport", "Anterograde axonal transport of mitochondrion", "Anterograde dendritic transport", "Anterograde dendritic transport of neurotransmitter receptor complex", "Anterograde neuronal dense core vesicle transport", "Antibacterial humoral response", "Antifungal innate immune response", "Antigen processing and presentation", "Antigen processing and presentation of endogenous antigen", "Antigen processing and presentation of endogenous peptide antigen", "Antigen processing and presentation of endogenous peptide antigen via mhc class i via er pathway", "Antigen processing and presentation of exogenous antigen", "Antigen processing and presentation of exogenous peptide antigen", "Antigen processing and presentation of exogenous peptide antigen via mhc class i", "Antigen processing and presentation of exogenous peptide antigen via mhc class ii", "Antigen processing and presentation of lipid antigen via mhc class ib", "Antigen processing and presentation of peptide antigen", "Antigen processing and presentation of peptide antigen via mhc class i", "Antigen processing and presentation of peptide antigen via mhc class ib", "Antigen processing and presentation of peptide or polysaccharide antigen via mhc class ii", "Antigen processing and presentation via mhc class ib", "Antigen receptor mediated signaling pathway", "Antimicrobial humoral immune response mediated by antimicrobial peptide", "Antimicrobial humoral response", "Antiviral innate immune response", "Aorta development", "Aorta morphogenesis", "Aortic valve morphogenesis", "Apical junction assembly", "Apical protein localization", "Apolipoprotein a i mediated signaling pathway", "Apoptotic cell clearance", "Apoptotic chromosome condensation", "Apoptotic dna fragmentation", "Apoptotic mitochondrial changes", "Apoptotic process involved in blood vessel morphogenesis", "Apoptotic process involved in development", "Apoptotic process involved in morphogenesis", "Apoptotic signaling pathway", "Appendage development", "Appendage morphogenesis", "Arachidonic acid metabolic process", "Arachidonic acid secretion", "Arf protein signal transduction", "Arginine catabolic process", "Arginine metabolic process", "Aromatic amino acid family catabolic process", "Aromatic amino acid family metabolic process", "Aromatic amino acid transport", "Arp2 3 complex mediated actin nucleation", "Artery development", "Artery morphogenesis", "Asparagine metabolic process", "Aspartate family amino acid biosynthetic process", "Aspartate family amino acid catabolic process", "Aspartate family amino acid metabolic process", "Aspartate metabolic process", "Aspartate transmembrane transport", "Associative learning", "Astral microtubule organization", "Astrocyte activation", "Astrocyte cell migration", "Astrocyte development", "Astrocyte differentiation", "Asymmetric cell division", "Asymmetric neuroblast division", "Atf6 mediated unfolded protein response", "Atp biosynthetic process", "Atp metabolic process", "Atp synthesis coupled electron transport", "Atp synthesis coupled proton transport", "Atp transport", "Atrial cardiac muscle cell membrane repolarization", "Atrial cardiac muscle cell to av node cell signaling", "Atrial septum development", "Atrial septum morphogenesis", "Atrioventricular canal development", "Atrioventricular node development", "Attachment of gpi anchor to protein", "Attachment of mitotic spindle microtubules to kinetochore", "Attachment of spindle microtubules to kinetochore", "Auditory receptor cell development", "Auditory receptor cell morphogenesis", "Autonomic nervous system development", "Autophagic cell death", "Autophagosome lysosome fusion", "Autophagosome maturation", "Autophagosome membrane docking", "Autophagosome organization", "Autophagy of mitochondrion", "Autophagy of nucleus", "Autophagy of peroxisome", "Av node cell to bundle of his cell communication", "Av node cell to bundle of his cell signaling", "Axial mesoderm development", "Axis elongation", "Axis specification", "Axo dendritic protein transport", "Axo dendritic transport", "Axon choice point recognition", "Axon development", "Axon ensheathment in central nervous system", "Axon extension", "Axon midline choice point recognition", "Axonal fasciculation", "Axonal transport", "Axonal transport of mitochondrion", "Axonemal dynein complex assembly", "Axoneme assembly", "Axonogenesis involved in innervation", "Azole transmembrane transport", "B cell activation", "B cell activation involved in immune response", "B cell apoptotic process", "B cell differentiation", "B cell homeostasis", "B cell lineage commitment", "B cell mediated immunity", "B cell proliferation", "B cell receptor signaling pathway", "Barbed end actin filament capping", "Base conversion or substitution editing", "Base excision repair", "Base excision repair ap site formation", "Base excision repair gap filling", "Basement membrane assembly", "Basement membrane organization", "Basic amino acid transport", "Behavior", "Behavioral response to cocaine", "Behavioral response to ethanol", "Behavioral response to pain", "Benzene containing compound metabolic process", "Bergmann glial cell differentiation", "Bicarbonate transport", "Bile acid and bile salt transport", "Bile acid biosynthetic process", "Bile acid metabolic process", "Bile acid secretion", "Binding of sperm to zona pellucida", "Biological adhesion", "Biological phase", "Biological process involved in interaction with host", "Biological process involved in interaction with symbiont", "Biological process involved in interspecies interaction between organisms", "Biological process involved in intraspecies interaction between organisms", "Biological process involved in symbiotic interaction", "Biomineralization", "Blastocyst development", "Blastocyst formation", "Blastocyst growth", "Blastoderm segmentation", "Bleb assembly", "Blood vessel endothelial cell differentiation", "Blood vessel endothelial cell migration", "Blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Blood vessel maturation", "Blood vessel morphogenesis", "Blood vessel remodeling", "Body fluid secretion", "Body morphogenesis", "Bone cell development", "Bone development", "Bone growth", "Bone marrow development", "Bone maturation", "Bone mineralization", "Bone mineralization involved in bone maturation", "Bone morphogenesis", "Bone remodeling", "Bone resorption", "Box c d snornp assembly", "Bradykinin catabolic process", "Brain derived neurotrophic factor receptor signaling pathway", "Brain morphogenesis", "Brainstem development", "Branch elongation of an epithelium", "Branched chain amino acid biosynthetic process", "Branched chain amino acid catabolic process", "Branched chain amino acid metabolic process", "Branched chain amino acid transport", "Branching involved in blood vessel morphogenesis", "Branching involved in labyrinthine layer morphogenesis", "Branching involved in mammary gland duct morphogenesis", "Branching involved in salivary gland morphogenesis", "Branching morphogenesis of a nerve", "Branching morphogenesis of an epithelial tube", "Branchiomotor neuron axon guidance", "Brown fat cell differentiation", "Bundle of his cell to purkinje myocyte communication", "C 5 methylation of cytosine", "C terminal protein amino acid modification", "C terminal protein lipidation", "C21 steroid hormone biosynthetic process", "C21 steroid hormone metabolic process", "C4 dicarboxylate transport", "Cadmium ion transmembrane transport", "Calcineurin mediated signaling", "Calcium activated phospholipid scrambling", "Calcium dependent cell cell adhesion via plasma membrane cell adhesion molecules", "Calcium import into the mitochondrion", "Calcium ion export", "Calcium ion export across plasma membrane", "Calcium ion import", "Calcium ion import into cytosol", "Calcium ion import into sarcoplasmic reticulum", "Calcium ion regulated exocytosis", "Calcium ion regulated exocytosis of neurotransmitter", "Calcium ion transmembrane transport", "Calcium ion transmembrane transport via high voltage gated calcium channel", "Calcium ion transport", "Calcium ion transport into cytosol", "Calcium mediated signaling", "Calcium mediated signaling using intracellular calcium source", "Calmodulin dependent kinase signaling pathway", "Camera type eye development", "Camera type eye morphogenesis", "Camera type eye photoreceptor cell differentiation", "Camp mediated signaling", "Cannabinoid signaling pathway", "Canonical wnt signaling pathway", "Canonical wnt signaling pathway involved in heart development", "Canonical wnt signaling pathway involved in osteoblast differentiation", "Canonical wnt signaling pathway involved in regulation of cell proliferation", "Cap dependent translational initiation", "Carbohydrate biosynthetic process", "Carbohydrate catabolic process", "Carbohydrate derivative biosynthetic process", "Carbohydrate derivative catabolic process", "Carbohydrate derivative metabolic process", "Carbohydrate derivative transport", "Carbohydrate homeostasis", "Carbohydrate import across plasma membrane", "Carbohydrate mediated signaling", "Carbohydrate metabolic process", "Carbohydrate phosphorylation", "Carbohydrate transmembrane transport", "Carbohydrate transport", "Carboxylic acid transport", "Cardiac atrium development", "Cardiac atrium morphogenesis", "Cardiac cell development", "Cardiac chamber development", "Cardiac chamber morphogenesis", "Cardiac conduction", "Cardiac conduction system development", "Cardiac epithelial to mesenchymal transition", "Cardiac left ventricle morphogenesis", "Cardiac muscle cell action potential", "Cardiac muscle cell action potential involved in contraction", "Cardiac muscle cell cardiac muscle cell adhesion", "Cardiac muscle cell contraction", "Cardiac muscle cell differentiation", "Cardiac muscle cell membrane repolarization", "Cardiac muscle cell proliferation", "Cardiac muscle contraction", "Cardiac muscle tissue development", "Cardiac muscle tissue morphogenesis", "Cardiac myofibril assembly", "Cardiac neural crest cell development involved in outflow tract morphogenesis", "Cardiac neural crest cell differentiation involved in heart development", "Cardiac neural crest cell migration involved in outflow tract morphogenesis", "Cardiac right ventricle morphogenesis", "Cardiac septum development", "Cardiac septum morphogenesis", "Cardiac ventricle development", "Cardiac ventricle morphogenesis", "Cardioblast differentiation", "Cardioblast proliferation", "Cardiocyte differentiation", "Cardiolipin acyl chain remodeling", "Cardiolipin biosynthetic process", "Cardiolipin metabolic process", "Carnitine metabolic process", "Carnitine transport", "Cartilage development", "Cartilage development involved in endochondral bone morphogenesis", "Catechol containing compound biosynthetic process", "Catechol containing compound catabolic process", "Catechol containing compound metabolic process", "Catecholamine secretion", "Catecholamine uptake", "Catecholamine uptake involved in synaptic transmission", "Cation transmembrane transport", "Cation transport", "Caveola assembly", "Caveolin mediated endocytosis", "Cd4 positive alpha beta t cell activation", "Cd4 positive alpha beta t cell differentiation", "Cd4 positive alpha beta t cell proliferation", "Cd4 positive or cd8 positive alpha beta t cell lineage commitment", "Cd40 signaling pathway", "Cd8 positive alpha beta t cell activation", "Cd8 positive alpha beta t cell proliferation", "Cdc42 protein signal transduction", "Cdp choline pathway", "Cdp diacylglycerol metabolic process", "Cell activation", "Cell activation involved in immune response", "Cell adhesion mediated by integrin", "Cell adhesion molecule production", "Cell aggregation", "Cell aging", "Cell cell adhesion", "Cell cell adhesion involved in gastrulation", "Cell cell adhesion mediated by cadherin", "Cell cell adhesion mediated by integrin", "Cell cell adhesion via plasma membrane adhesion molecules", "Cell cell junction assembly", "Cell cell junction maintenance", "Cell cell junction organization", "Cell cell recognition", "Cell cell signaling", "Cell cell signaling by wnt", "Cell cell signaling involved in cardiac conduction", "Cell chemotaxis", "Cell communication by electrical coupling", "Cell communication by electrical coupling involved in cardiac conduction", "Cell communication involved in cardiac conduction", "Cell cycle", "Cell cycle checkpoint signaling", "Cell cycle dna replication", "Cell cycle dna replication initiation", "Cell cycle g1 s phase transition", "Cell cycle g2 m phase transition", "Cell cycle phase transition", "Cell cycle process", "Cell death in response to hydrogen peroxide", "Cell death in response to oxidative stress", "Cell differentiation in hindbrain", "Cell differentiation in spinal cord", "Cell differentiation involved in embryonic placenta development", "Cell differentiation involved in kidney development", "Cell differentiation involved in metanephros development", "Cell differentiation involved in phenotypic switching", "Cell division", "Cell fate commitment", "Cell fate commitment involved in formation of primary germ layer", "Cell fate determination", "Cell fate specification", "Cell growth", "Cell junction assembly", "Cell junction disassembly", "Cell junction maintenance", "Cell junction organization", "Cell killing", "Cell matrix adhesion", "Cell maturation", "Cell migration", "Cell migration in hindbrain", "Cell migration involved in gastrulation", "Cell migration involved in heart development", "Cell migration involved in sprouting angiogenesis", "Cell morphogenesis", "Cell morphogenesis involved in differentiation", "Cell morphogenesis involved in neuron differentiation", "Cell motility involved in cerebral cortex radial glia guided migration", "Cell part morphogenesis", "Cell projection assembly", "Cell projection organization", "Cell proliferation in forebrain", "Cell proliferation in hindbrain", "Cell proliferation involved in heart morphogenesis", "Cell proliferation involved in kidney development", "Cell proliferation involved in metanephros development", "Cell recognition", "Cell redox homeostasis", "Cell substrate adhesion", "Cell substrate junction organization", "Cell surface receptor signaling pathway involved in cell cell signaling", "Cell surface receptor signaling pathway involved in heart development", "Cell volume homeostasis", "Cellular aldehyde metabolic process", "Cellular amide metabolic process", "Cellular amino acid biosynthetic process", "Cellular amino acid catabolic process", "Cellular amino acid metabolic process", "Cellular anion homeostasis", "Cellular carbohydrate biosynthetic process", "Cellular carbohydrate catabolic process", "Cellular carbohydrate metabolic process", "Cellular component assembly involved in morphogenesis", "Cellular component disassembly", "Cellular component disassembly involved in execution phase of apoptosis", "Cellular component maintenance", "Cellular component morphogenesis", "Cellular copper ion homeostasis", "Cellular defense response", "Cellular detoxification of aldehyde", "Cellular extravasation", "Cellular glucan metabolic process", "Cellular glucose homeostasis", "Cellular homeostasis", "Cellular hormone metabolic process", "Cellular hyperosmotic response", "Cellular hyperosmotic salinity response", "Cellular hypotonic response", "Cellular ion homeostasis", "Cellular iron ion homeostasis", "Cellular ketone metabolic process", "Cellular lipid catabolic process", "Cellular lipid metabolic process", "Cellular macromolecule biosynthetic process", "Cellular macromolecule localization", "Cellular metabolic compound salvage", "Cellular modified amino acid biosynthetic process", "Cellular modified amino acid catabolic process", "Cellular modified amino acid metabolic process", "Cellular monovalent inorganic anion homeostasis", "Cellular monovalent inorganic cation homeostasis", "Cellular nitrogen compound catabolic process", "Cellular oxidant detoxification", "Cellular pigmentation", "Cellular polysaccharide catabolic process", "Cellular potassium ion homeostasis", "Cellular process involved in reproduction in multicellular organism", "Cellular protein catabolic process", "Cellular respiration", "Cellular response to abiotic stimulus", "Cellular response to acid chemical", "Cellular response to acidic ph", "Cellular response to alcohol", "Cellular response to aldehyde", "Cellular response to alkaloid", "Cellular response to amyloid beta", "Cellular response to antibiotic", "Cellular response to arsenic containing substance", "Cellular response to atp", "Cellular response to biotic stimulus", "Cellular response to brain derived neurotrophic factor stimulus", "Cellular response to cadmium ion", "Cellular response to caffeine", "Cellular response to calcium ion", "Cellular response to camp", "Cellular response to carbohydrate stimulus", "Cellular response to chemical stress", "Cellular response to cold", "Cellular response to copper ion", "Cellular response to corticosteroid stimulus", "Cellular response to dexamethasone stimulus", "Cellular response to dna damage stimulus", "Cellular response to dsrna", "Cellular response to electrical stimulus", "Cellular response to endogenous stimulus", "Cellular response to epinephrine stimulus", "Cellular response to estradiol stimulus", "Cellular response to estrogen stimulus", "Cellular response to ethanol", "Cellular response to ether", "Cellular response to exogenous dsrna", "Cellular response to external stimulus", "Cellular response to extracellular stimulus", "Cellular response to fatty acid", "Cellular response to fluid shear stress", "Cellular response to follicle stimulating hormone stimulus", "Cellular response to gamma radiation", "Cellular response to glucose starvation", "Cellular response to gonadotropin stimulus", "Cellular response to growth hormone stimulus", "Cellular response to heat", "Cellular response to heparin", "Cellular response to histamine", "Cellular response to hormone stimulus", "Cellular response to hydrogen peroxide", "Cellular response to hydroperoxide", "Cellular response to hyperoxia", "Cellular response to increased oxygen levels", "Cellular response to indole 3 methanol", "Cellular response to inorganic substance", "Cellular response to insulin like growth factor stimulus", "Cellular response to insulin stimulus", "Cellular response to interferon alpha", "Cellular response to interferon beta", "Cellular response to interferon gamma", "Cellular response to interleukin 1", "Cellular response to ionizing radiation", "Cellular response to iron ion", "Cellular response to ketone", "Cellular response to leptin stimulus", "Cellular response to leucine", "Cellular response to leucine starvation", "Cellular response to light intensity", "Cellular response to light stimulus", "Cellular response to lipid", "Cellular response to lipoprotein particle stimulus", "Cellular response to lithium ion", "Cellular response to low density lipoprotein particle stimulus", "Cellular response to magnesium ion", "Cellular response to manganese ion", "Cellular response to mechanical stimulus", "Cellular response to mineralocorticoid stimulus", "Cellular response to molecule of bacterial origin", "Cellular response to muramyl dipeptide", "Cellular response to nitrogen compound", "Cellular response to nitrogen starvation", "Cellular response to nitrosative stress", "Cellular response to nutrient", "Cellular response to organic cyclic compound", "Cellular response to osmotic stress", "Cellular response to oxidised low density lipoprotein particle stimulus", "Cellular response to oxygen containing compound", "Cellular response to oxygen glucose deprivation", "Cellular response to oxygen levels", "Cellular response to oxygen radical", "Cellular response to parathyroid hormone stimulus", "Cellular response to peptide", "Cellular response to peptide hormone stimulus", "Cellular response to peptidoglycan", "Cellular response to ph", "Cellular response to potassium ion", "Cellular response to prostaglandin e stimulus", "Cellular response to prostaglandin stimulus", "Cellular response to purine containing compound", "Cellular response to radiation", "Cellular response to reactive nitrogen species", "Cellular response to reactive oxygen species", "Cellular response to retinoic acid", "Cellular response to salt", "Cellular response to salt stress", "Cellular response to sodium arsenite", "Cellular response to starvation", "Cellular response to steroid hormone stimulus", "Cellular response to sterol depletion", "Cellular response to stress", "Cellular response to testosterone stimulus", "Cellular response to thyroid hormone stimulus", "Cellular response to topologically incorrect protein", "Cellular response to toxic substance", "Cellular response to unfolded protein", "Cellular response to uv", "Cellular response to uv a", "Cellular response to uv c", "Cellular response to vascular endothelial growth factor stimulus", "Cellular response to virus", "Cellular response to vitamin", "Cellular response to vitamin d", "Cellular response to water stimulus", "Cellular response to x ray", "Cellular response to xenobiotic stimulus", "Cellular response to zinc ion", "Cellular senescence", "Cellular sodium ion homeostasis", "Cellular sphingolipid homeostasis", "Cellular transition metal ion homeostasis", "Cellular triglyceride homeostasis", "Cellular trivalent inorganic anion homeostasis", "Cenp a containing chromatin organization", "Central nervous system development", "Central nervous system maturation", "Central nervous system myelin formation", "Central nervous system myelin maintenance", "Central nervous system neuron axonogenesis", "Central nervous system neuron development", "Central nervous system neuron differentiation", "Central nervous system projection neuron axonogenesis", "Centriole assembly", "Centriole centriole cohesion", "Centriole elongation", "Centromere complex assembly", "Centromeric sister chromatid cohesion", "Centrosome duplication", "Centrosome separation", "Ceramide 1 phosphate transport", "Ceramide biosynthetic process", "Ceramide catabolic process", "Ceramide metabolic process", "Ceramide transport", "Cerebellar cortex development", "Cerebellar cortex formation", "Cerebellar cortex morphogenesis", "Cerebellar granular layer development", "Cerebellar granular layer formation", "Cerebellar granular layer morphogenesis", "Cerebellar purkinje cell layer development", "Cerebellar purkinje cell layer formation", "Cerebellar purkinje cell layer morphogenesis", "Cerebral cortex cell migration", "Cerebral cortex development", "Cerebral cortex neuron differentiation", "Cerebral cortex radially oriented cell migration", "Cerebral cortex regionalization", "Cerebral cortex tangential migration", "Cerebrospinal fluid circulation", "Cgmp mediated signaling", "Changes to dna methylation involved in embryo development", "Chaperone cofactor dependent protein refolding", "Chaperone mediated autophagy", "Chaperone mediated protein complex assembly", "Chaperone mediated protein folding", "Chemical homeostasis", "Chemical homeostasis within a tissue", "Chemical synaptic transmission postsynaptic", "Chemokine c c motif ligand 5 production", "Chemokine c x c motif ligand 12 signaling pathway", "Chemokine c x c motif ligand 2 production", "Chemokine production", "Chemosensory behavior", "Chiasma assembly", "Chloride transmembrane transport", "Chloride transport", "Cholesterol catabolic process", "Cholesterol efflux", "Cholesterol storage", "Choline metabolic process", "Chondrocyte development", "Chondrocyte development involved in endochondral bone morphogenesis", "Chondrocyte differentiation", "Chondrocyte differentiation involved in endochondral bone morphogenesis", "Chondrocyte proliferation", "Chondroitin sulfate biosynthetic process", "Chondroitin sulfate proteoglycan biosynthetic process", "Chondroitin sulfate proteoglycan metabolic process", "Chorio allantoic fusion", "Chorion development", "Chromatin assembly or disassembly", "Chromatin disassembly", "Chromatin organization", "Chromatin remodeling", "Chromatin remodeling at centromere", "Chromosome attachment to the nuclear envelope", "Chromosome condensation", "Chromosome localization", "Chromosome localization to nuclear envelope involved in homologous chromosome segregation", "Chromosome movement towards spindle pole", "Chromosome organization", "Chromosome organization involved in meiotic cell cycle", "Chromosome segregation", "Chromosome separation", "Cilium movement", "Cilium or flagellum dependent cell motility", "Cilium organization", "Circadian regulation of gene expression", "Circadian rhythm", "Circulatory system development", "Circulatory system process", "Citrate metabolic process", "Citrulline biosynthetic process", "Citrulline metabolic process", "Clathrin coat assembly", "Clathrin dependent endocytosis", "Cleavage furrow formation", "Cleavage involved in rrna processing", "Cobalamin metabolic process", "Cobalamin transport", "Cobalt ion transport", "Cochlea development", "Cochlea morphogenesis", "Coenzyme a biosynthetic process", "Coenzyme a metabolic process", "Cognition", "Cohesin loading", "Collagen activated signaling pathway", "Collagen biosynthetic process", "Collagen catabolic process", "Collagen fibril organization", "Collagen metabolic process", "Collateral sprouting", "Collateral sprouting in absence of injury", "Collecting duct development", "Columnar cuboidal epithelial cell development", "Columnar cuboidal epithelial cell differentiation", "Columnar cuboidal epithelial cell maturation", "Commissural neuron axon guidance", "Common bile duct development", "Common partner smad protein phosphorylation", "Complement activation", "Complement dependent cytotoxicity", "Connective tissue development", "Connective tissue replacement", "Constitutive heterochromatin assembly", "Constitutive secretory pathway", "Convergent extension", "Convergent extension involved in axis elongation", "Convergent extension involved in gastrulation", "Convergent extension involved in organogenesis", "Cop9 signalosome assembly", "Copi coated vesicle budding", "Copii coated vesicle budding", "Copii coated vesicle cargo loading", "Copper ion homeostasis", "Copper ion transport", "Copulation", "Cornea development in camera type eye", "Coronary artery morphogenesis", "Coronary vasculature development", "Coronary vasculature morphogenesis", "Corpus callosum development", "Corpus callosum morphogenesis", "Cortical actin cytoskeleton organization", "Cortical cytoskeleton organization", "Corticospinal tract morphogenesis", "Corticosteroid hormone secretion", "Corticosteroid receptor signaling pathway", "Cortisol secretion", "Cotranslational protein targeting to membrane", "Cranial ganglion development", "Cranial nerve development", "Cranial nerve morphogenesis", "Cranial nerve structural organization", "Cranial skeletal system development", "Craniofacial suture morphogenesis", "Crd mediated mrna stabilization", "Cristae formation", "Cyclic gmp amp transmembrane import across plasma membrane", "Cyclic nucleotide biosynthetic process", "Cyclic nucleotide catabolic process", "Cyclic nucleotide mediated signaling", "Cyclic nucleotide metabolic process", "Cyclooxygenase pathway", "Cysteine metabolic process", "Cytidine metabolic process", "Cytidine to uridine editing", "Cytochrome complex assembly", "Cytokine mediated signaling pathway", "Cytokine production", "Cytokine production involved in immune response", "Cytokine production involved in inflammatory response", "Cytokinesis", "Cytokinetic process", "Cytoplasm organization", "Cytoplasmic microtubule organization", "Cytoplasmic pattern recognition receptor signaling pathway", "Cytoplasmic pattern recognition receptor signaling pathway in response to virus", "Cytoplasmic sequestering of nf kappab", "Cytoplasmic sequestering of protein", "Cytoplasmic sequestering of transcription factor", "Cytoplasmic translation", "Cytoplasmic translational elongation", "Cytoplasmic translational initiation", "Cytoskeleton dependent cytokinesis", "Cytoskeleton dependent intracellular transport", "Cytoskeleton organization", "Cytosolic calcium ion transport", "Cytosolic transport", "D amino acid transport", "Damp metabolic process", "De novo amp biosynthetic process", "De novo nad biosynthetic process", "De novo protein folding", "De novo pyrimidine nucleobase biosynthetic process", "Deadenylation dependent decapping of nuclear transcribed mrna", "Decidualization", "Dedifferentiation", "Defense response", "Defense response to bacterium", "Defense response to fungus", "Defense response to gram negative bacterium", "Defense response to gram positive bacterium", "Defense response to other organism", "Defense response to symbiont", "Defense response to tumor cell", "Definitive erythrocyte differentiation", "Definitive hemopoiesis", "Dehydroascorbic acid transport", "Delamination", "Demethylation", "Dendrite arborization", "Dendrite development", "Dendrite extension", "Dendrite morphogenesis", "Dendrite self avoidance", "Dendritic cell apoptotic process", "Dendritic cell chemotaxis", "Dendritic cell cytokine production", "Dendritic cell differentiation", "Dendritic cell migration", "Dendritic spine development", "Dendritic spine maintenance", "Dendritic spine morphogenesis", "Dendritic transport", "Dense core granule transport", "Dentate gyrus development", "Deoxyribonucleoside catabolic process", "Deoxyribonucleoside diphosphate metabolic process", "Deoxyribonucleoside metabolic process", "Deoxyribonucleoside monophosphate biosynthetic process", "Deoxyribonucleoside monophosphate catabolic process", "Deoxyribonucleoside monophosphate metabolic process", "Deoxyribonucleoside triphosphate biosynthetic process", "Deoxyribonucleoside triphosphate catabolic process", "Deoxyribonucleoside triphosphate metabolic process", "Deoxyribonucleotide biosynthetic process", "Deoxyribose phosphate catabolic process", "Deoxyribose phosphate metabolic process", "Dephosphorylation", "Dephosphorylation of rna polymerase ii c terminal domain", "Depyrimidination", "Dermatan sulfate biosynthetic process", "Dermatan sulfate metabolic process", "Dermatan sulfate proteoglycan metabolic process", "Desmosome organization", "Detection of abiotic stimulus", "Detection of biotic stimulus", "Detection of calcium ion", "Detection of cell density", "Detection of external biotic stimulus", "Detection of light stimulus", "Detection of light stimulus involved in sensory perception", "Detection of mechanical stimulus", "Detection of mechanical stimulus involved in sensory perception", "Detection of mechanical stimulus involved in sensory perception of pain", "Detection of molecule of bacterial origin", "Detection of muscle stretch", "Detection of other organism", "Detection of stimulus", "Detection of stimulus involved in sensory perception", "Detection of stimulus involved in sensory perception of pain", "Detection of temperature stimulus", "Detection of temperature stimulus involved in sensory perception", "Detection of temperature stimulus involved in sensory perception of pain", "Detection of virus", "Detection of visible light", "Determination of adult lifespan", "Determination of dorsal ventral asymmetry", "Detoxification", "Detoxification of copper ion", "Detoxification of nitrogen compound", "Development of primary female sexual characteristics", "Development of primary sexual characteristics", "Development of secondary female sexual characteristics", "Development of secondary sexual characteristics", "Developmental cell growth", "Developmental growth", "Developmental growth involved in morphogenesis", "Developmental induction", "Developmental maturation", "Developmental pigmentation", "Developmental process involved in reproduction", "Diacylglycerol biosynthetic process", "Diacylglycerol metabolic process", "Diadenosine polyphosphate catabolic process", "Diadenosine polyphosphate metabolic process", "Diapedesis", "Diaphragm development", "Dicarboxylic acid biosynthetic process", "Dicarboxylic acid catabolic process", "Dicarboxylic acid metabolic process", "Dicarboxylic acid transport", "Dichotomous subdivision of an epithelial terminal unit", "Dichotomous subdivision of terminal units involved in salivary gland branching", "Diencephalon development", "Diet induced thermogenesis", "Digestion", "Digestive system development", "Digestive system process", "Digestive tract morphogenesis", "Diol biosynthetic process", "Diol metabolic process", "Diphosphoinositol polyphosphate metabolic process", "Disaccharide metabolic process", "Diterpenoid biosynthetic process", "Divalent inorganic cation homeostasis", "Dna biosynthetic process", "Dna catabolic process", "Dna catabolic process endonucleolytic", "Dna catabolic process exonucleolytic", "Dna conformation change", "Dna cytosine deamination", "Dna damage induced protein phosphorylation", "Dna damage response signal transduction by p53 class mediator", "Dna damage response signal transduction by p53 class mediator resulting in cell cycle arrest", "Dna damage response signal transduction resulting in transcription", "Dna dealkylation", "Dna dealkylation involved in dna repair", "Dna deamination", "Dna dependent dna replication", "Dna dependent dna replication maintenance of fidelity", "Dna double strand break processing", "Dna endoreduplication", "Dna geometric change", "Dna integration", "Dna integrity checkpoint signaling", "Dna ligation", "Dna ligation involved in dna repair", "Dna metabolic process", "Dna methylation", "Dna methylation dependent heterochromatin assembly", "Dna methylation involved in gamete generation", "Dna methylation on cytosine", "Dna methylation or demethylation", "Dna modification", "Dna packaging", "Dna protection", "Dna recombination", "Dna repair", "Dna replication", "Dna replication checkpoint signaling", "Dna replication dependent chromatin organization", "Dna replication independent chromatin organization", "Dna replication initiation", "Dna replication synthesis of rna primer", "Dna strand elongation", "Dna strand elongation involved in dna replication", "Dna synthesis involved in dna repair", "Dna templated transcription elongation", "Dna templated transcription initiation", "Dna templated transcription termination", "Dna topological change", "Dna unwinding involved in dna replication", "Dolichol metabolic process", "Dolichyl diphosphate biosynthetic process", "Dopamine biosynthetic process", "Dopamine metabolic process", "Dopamine receptor signaling pathway", "Dopamine secretion", "Dopamine transport", "Dopaminergic neuron differentiation", "Dorsal root ganglion development", "Dorsal ventral axis specification", "Dorsal ventral neural tube patterning", "Dorsal ventral pattern formation", "Dosage compensation", "Double strand break repair", "Double strand break repair involved in meiotic recombination", "Double strand break repair via break induced replication", "Double strand break repair via classical nonhomologous end joining", "Double strand break repair via nonhomologous end joining", "Double strand break repair via synthesis dependent strand annealing", "Dsrna processing", "Dtmp metabolic process", "Dttp metabolic process", "Dump metabolic process", "Ear development", "Ear morphogenesis", "Early endosome to golgi transport", "Eating behavior", "Ectoderm development", "Ectodermal placode development", "Ectopic germ cell programmed cell death", "Egg activation", "Electron transport chain", "Embryo development", "Embryo development ending in birth or egg hatching", "Embryo implantation", "Embryonic appendage morphogenesis", "Embryonic axis specification", "Embryonic body morphogenesis", "Embryonic brain development", "Embryonic camera type eye development", "Embryonic camera type eye morphogenesis", "Embryonic cleavage", "Embryonic cranial skeleton morphogenesis", "Embryonic digestive tract development", "Embryonic digestive tract morphogenesis", "Embryonic digit morphogenesis", "Embryonic eye morphogenesis", "Embryonic forelimb morphogenesis", "Embryonic heart tube development", "Embryonic heart tube morphogenesis", "Embryonic hemopoiesis", "Embryonic hindlimb morphogenesis", "Embryonic morphogenesis", "Embryonic neurocranium morphogenesis", "Embryonic organ development", "Embryonic organ morphogenesis", "Embryonic pattern specification", "Embryonic placenta development", "Embryonic placenta morphogenesis", "Embryonic process involved in female pregnancy", "Embryonic skeletal joint development", "Embryonic skeletal joint morphogenesis", "Embryonic skeletal system development", "Embryonic skeletal system morphogenesis", "Embryonic viscerocranium morphogenesis", "Enamel mineralization", "Endocannabinoid signaling pathway", "Endocardium development", "Endochondral bone morphogenesis", "Endocrine hormone secretion", "Endocrine pancreas development", "Endocrine process", "Endocrine system development", "Endocytic recycling", "Endocytosis", "Endocytosis involved in viral entry into host cell", "Endoderm development", "Endoderm formation", "Endodermal cell differentiation", "Endodermal cell fate commitment", "Endomembrane system organization", "Endonucleolytic cleavage in 5 ets of tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage in its1 to separate ssu rrna from 5 8s rrna and lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Endonucleolytic cleavage involved in rrna processing", "Endoplasmic reticulum calcium ion homeostasis", "Endoplasmic reticulum localization", "Endoplasmic reticulum mannose trimming", "Endoplasmic reticulum membrane organization", "Endoplasmic reticulum organization", "Endoplasmic reticulum plasma membrane tethering", "Endoplasmic reticulum to cytosol transport", "Endoplasmic reticulum to golgi vesicle mediated transport", "Endoplasmic reticulum tubular network organization", "Endoplasmic reticulum unfolded protein response", "Endosomal lumen acidification", "Endosomal transport", "Endosomal vesicle fusion", "Endosome organization", "Endosome to lysosome transport", "Endosome to lysosome transport via multivesicular body sorting pathway", "Endosome to plasma membrane protein transport", "Endosome transport via multivesicular body sorting pathway", "Endothelial cell activation", "Endothelial cell apoptotic process", "Endothelial cell chemotaxis", "Endothelial cell development", "Endothelial cell fate commitment", "Endothelial cell matrix adhesion", "Endothelial cell migration", "Endothelial cell morphogenesis", "Endothelial cell proliferation", "Endothelin receptor signaling pathway", "Endothelium development", "Energy derivation by oxidation of organic compounds", "Energy homeostasis", "Energy reserve metabolic process", "Engulfment of apoptotic cell", "Ensheathment of neurons", "Enteroendocrine cell differentiation", "Entrainment of circadian clock", "Entry into host", "Entry of bacterium into host cell", "Enucleate erythrocyte differentiation", "Enzyme directed rrna pseudouridine synthesis", "Enzyme linked receptor protein signaling pathway", "Eosinophil activation", "Eosinophil chemotaxis", "Eosinophil mediated immunity", "Eosinophil migration", "Ephrin receptor signaling pathway", "Epiboly", "Epidermal cell differentiation", "Epidermis development", "Epidermis morphogenesis", "Epigenetic maintenance of chromatin in transcription competent conformation", "Epithelial cell apoptotic process", "Epithelial cell cell adhesion", "Epithelial cell development", "Epithelial cell differentiation", "Epithelial cell differentiation involved in kidney development", "Epithelial cell differentiation involved in prostate gland development", "Epithelial cell fate commitment", "Epithelial cell maturation", "Epithelial cell morphogenesis", "Epithelial cell proliferation", "Epithelial cell proliferation involved in lung morphogenesis", "Epithelial cell proliferation involved in prostate gland development", "Epithelial fluid transport", "Epithelial structure maintenance", "Epithelial to mesenchymal transition", "Epithelial tube branching involved in lung morphogenesis", "Epithelial tube formation", "Epithelial tube morphogenesis", "Epithelium development", "Epoxide metabolic process", "Er associated misfolded protein catabolic process", "Er nucleus signaling pathway", "Er overload response", "Erad pathway", "Erbb signaling pathway", "Erbb2 signaling pathway", "Erk1 and erk2 cascade", "Error free translesion synthesis", "Error prone translesion synthesis", "Erythrocyte development", "Erythrocyte homeostasis", "Erythrocyte maturation", "Escrt complex disassembly", "Establishment of cell polarity", "Establishment of centrosome localization", "Establishment of endothelial barrier", "Establishment of endothelial intestinal barrier", "Establishment of epithelial cell apical basal polarity", "Establishment of epithelial cell polarity", "Establishment of golgi localization", "Establishment of lymphocyte polarity", "Establishment of meiotic spindle localization", "Establishment of mitochondrion localization", "Establishment of mitotic spindle localization", "Establishment of organelle localization", "Establishment of pigment granule localization", "Establishment of planar polarity involved in neural tube closure", "Establishment of planar polarity of embryonic epithelium", "Establishment of protein localization", "Establishment of protein localization to chromatin", "Establishment of protein localization to chromosome", "Establishment of protein localization to endoplasmic reticulum", "Establishment of protein localization to membrane", "Establishment of protein localization to mitochondrial membrane", "Establishment of protein localization to organelle", "Establishment of protein localization to plasma membrane", "Establishment of protein localization to telomere", "Establishment of protein localization to vacuole", "Establishment of rna localization", "Establishment of sister chromatid cohesion", "Establishment of spindle orientation", "Establishment of tissue polarity", "Establishment or maintenance of bipolar cell polarity", "Establishment or maintenance of cell polarity", "Establishment or maintenance of cytoskeleton polarity", "Establishment or maintenance of monopolar cell polarity", "Establishment or maintenance of transmembrane electrochemical gradient", "Estrogen biosynthetic process", "Estrogen metabolic process", "Estrous cycle", "Ethanol catabolic process", "Ethanol metabolic process", "Ethanol oxidation", "Ethanolamine containing compound metabolic process", "Ether biosynthetic process", "Ether metabolic process", "Excitatory synapse assembly", "Excretion", "Execution phase of apoptosis", "Exit from mitosis", "Exocrine pancreas development", "Exocrine system development", "Exocyst localization", "Exocytic process", "Exocytosis", "Exonucleolytic catabolism of deadenylated mrna", "Exploration behavior", "Export across plasma membrane", "Export from cell", "External encapsulating structure organization", "Extracellular exosome assembly", "Extracellular matrix assembly", "Extracellular matrix constituent secretion", "Extracellular matrix disassembly", "Extracellular regulation of signal transduction", "Extracellular transport", "Extracellular vesicle biogenesis", "Extraembryonic membrane development", "Extrinsic apoptotic signaling pathway", "Extrinsic apoptotic signaling pathway via death domain receptors", "Eye morphogenesis", "Eye photoreceptor cell development", "Eye photoreceptor cell differentiation", "Eye pigmentation", "Eyelid development in camera type eye", "Face development", "Facial nerve morphogenesis", "Facial nerve structural organization", "Facultative heterochromatin assembly", "Farnesyl diphosphate metabolic process", "Fas signaling pathway", "Fat cell differentiation", "Fat cell proliferation", "Fat pad development", "Fat soluble vitamin biosynthetic process", "Fat soluble vitamin metabolic process", "Fatty acid alpha oxidation", "Fatty acid beta oxidation", "Fatty acid beta oxidation using acyl coa dehydrogenase", "Fatty acid beta oxidation using acyl coa oxidase", "Fatty acid biosynthetic process", "Fatty acid catabolic process", "Fatty acid derivative biosynthetic process", "Fatty acid derivative catabolic process", "Fatty acid derivative metabolic process", "Fatty acid elongation", "Fatty acid homeostasis", "Fatty acid metabolic process", "Fatty acid omega oxidation", "Fatty acid transmembrane transport", "Fatty acid transport", "Fatty acyl coa biosynthetic process", "Fatty acyl coa catabolic process", "Fatty acyl coa metabolic process", "Fc epsilon receptor signaling pathway", "Fc gamma receptor signaling pathway", "Fc receptor mediated stimulatory signaling pathway", "Fc receptor signaling pathway", "Fear response", "Feeding behavior", "Female gamete generation", "Female genitalia development", "Female meiosis chromosome segregation", "Female meiosis i", "Female meiotic nuclear division", "Female sex differentiation", "Fermentation", "Fertilization", "Fibroblast activation", "Fibroblast apoptotic process", "Fibroblast growth factor production", "Fibroblast growth factor receptor signaling pathway", "Fibroblast migration", "Fibroblast proliferation", "Filopodium assembly", "Flavin containing compound metabolic process", "Flavonoid metabolic process", "Fluid transport", "Foam cell differentiation", "Focal adhesion assembly", "Folate import across plasma membrane", "Folate transmembrane transport", "Folic acid containing compound biosynthetic process", "Folic acid containing compound catabolic process", "Folic acid containing compound metabolic process", "Folic acid metabolic process", "Folic acid transport", "Forebrain cell migration", "Forebrain development", "Forebrain dorsal ventral pattern formation", "Forebrain generation of neurons", "Forebrain morphogenesis", "Forebrain neuron development", "Forebrain neuron differentiation", "Forebrain neuron fate commitment", "Forebrain regionalization", "Foregut morphogenesis", "Forelimb morphogenesis", "Formate metabolic process", "Formation of extrachromosomal circular dna", "Formation of primary germ layer", "Formation of translation preinitiation complex", "Free ubiquitin chain polymerization", "Fructose 1 6 bisphosphate metabolic process", "Fructose 2 6 bisphosphate metabolic process", "Fructose 6 phosphate metabolic process", "Fructose metabolic process", "Fucose metabolic process", "Fucosylation", "Fungiform papilla development", "Fungiform papilla morphogenesis", "G protein coupled acetylcholine receptor signaling pathway", "G protein coupled glutamate receptor signaling pathway", "G protein coupled opioid receptor signaling pathway", "G protein coupled purinergic receptor signaling pathway", "G protein coupled receptor internalization", "G protein coupled receptor signaling pathway", "G protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger", "G protein coupled receptor signaling pathway involved in heart process", "G quadruplex dna unwinding", "G0 to g1 transition", "G1 to g0 transition", "Galactolipid biosynthetic process", "Galactolipid metabolic process", "Galactose catabolic process", "Galactose metabolic process", "Gamete generation", "Gamma aminobutyric acid metabolic process", "Gamma aminobutyric acid secretion", "Gamma aminobutyric acid signaling pathway", "Gamma aminobutyric acid transport", "Gamma delta t cell activation", "Ganglion development", "Ganglioside catabolic process", "Ganglioside metabolic process", "Gap junction assembly", "Gap junction mediated intercellular transport", "Gas homeostasis", "Gastric acid secretion", "Gastrulation", "Gastrulation with mouth forming second", "Gdp mannose metabolic process", "Gdp metabolic process", "Gene silencing by rna", "Generation of precursor metabolites and energy", "Genitalia development", "Genitalia morphogenesis", "Genomic imprinting", "Germ cell development", "Germ cell migration", "Germ cell proliferation", "Germinal center b cell differentiation", "Germinal center formation", "Gland development", "Gland morphogenesis", "Glandular epithelial cell development", "Glandular epithelial cell differentiation", "Glial cell apoptotic process", "Glial cell development", "Glial cell differentiation", "Glial cell fate commitment", "Glial cell migration", "Glial cell proliferation", "Gliogenesis", "Glomerular basement membrane development", "Glomerular epithelial cell development", "Glomerular epithelial cell differentiation", "Glomerular epithelium development", "Glomerular visceral epithelial cell migration", "Glomerulus development", "Glomerulus morphogenesis", "Glomerulus vasculature morphogenesis", "Glucan biosynthetic process", "Glucocorticoid biosynthetic process", "Glucocorticoid metabolic process", "Glucocorticoid secretion", "Glucosamine containing compound catabolic process", "Glucosamine containing compound metabolic process", "Glucose 6 phosphate metabolic process", "Glucose catabolic process", "Glucose import", "Glucose import across plasma membrane", "Glucose import in response to insulin stimulus", "Glucose metabolic process", "Glucosylceramide metabolic process", "Glutamate biosynthetic process", "Glutamate catabolic process", "Glutamate homeostasis", "Glutamate metabolic process", "Glutamate receptor signaling pathway", "Glutamate reuptake", "Glutamate secretion", "Glutamate secretion neurotransmission", "Glutamine family amino acid biosynthetic process", "Glutamine family amino acid catabolic process", "Glutamine family amino acid metabolic process", "Glutamine metabolic process", "Glutamine transport", "Glutathione metabolic process", "Glycerol 3 phosphate metabolic process", "Glycerol ether metabolic process", "Glycerolipid biosynthetic process", "Glycerolipid catabolic process", "Glycerolipid metabolic process", "Glycerophospholipid biosynthetic process", "Glycerophospholipid catabolic process", "Glycerophospholipid metabolic process", "Glycine biosynthetic process", "Glycine metabolic process", "Glycolipid biosynthetic process", "Glycolipid catabolic process", "Glycolipid transport", "Glycolytic fermentation", "Glycolytic process through fructose 6 phosphate", "Glycoprotein biosynthetic process", "Glycoprotein catabolic process", "Glycoprotein metabolic process", "Glycosaminoglycan catabolic process", "Glycoside catabolic process", "Glycoside metabolic process", "Glycosphingolipid biosynthetic process", "Glycosphingolipid metabolic process", "Glycosyl compound biosynthetic process", "Glycosyl compound catabolic process", "Glycosyl compound metabolic process", "Glycosylation", "Glycosylceramide biosynthetic process", "Glycosylceramide catabolic process", "Glycosylceramide metabolic process", "Glyoxylate metabolic process", "Gmp biosynthetic process", "Gmp metabolic process", "Gmp salvage", "Golgi disassembly", "Golgi localization", "Golgi organization", "Golgi ribbon formation", "Golgi to endosome transport", "Golgi to lysosome transport", "Golgi to plasma membrane protein transport", "Golgi to plasma membrane transport", "Golgi to vacuole transport", "Golgi vesicle budding", "Golgi vesicle transport", "Gonadotropin secretion", "Gpi anchor metabolic process", "Granulocyte activation", "Granulocyte chemotaxis", "Granulocyte differentiation", "Granulocyte migration", "Granzyme mediated programmed cell death signaling pathway", "Grooming behavior", "Growth", "Growth hormone receptor signaling pathway via jak stat", "Growth hormone secretion", "Growth plate cartilage chondrocyte differentiation", "Growth plate cartilage development", "Gtp biosynthetic process", "Gtp metabolic process", "Guanine metabolic process", "Guanine nucleotide transmembrane transport", "Guanine nucleotide transport", "Hair cell differentiation", "Hair cycle phase", "Hair follicle maturation", "Hair follicle placode formation", "Head development", "Head morphogenesis", "Heart development", "Heart formation", "Heart growth", "Heart morphogenesis", "Heart process", "Heart trabecula formation", "Heart trabecula morphogenesis", "Heart valve development", "Heart valve morphogenesis", "Heat acclimation", "Heat generation", "Hematopoietic progenitor cell differentiation", "Hematopoietic stem cell differentiation", "Hematopoietic stem cell homeostasis", "Hematopoietic stem cell migration", "Hematopoietic stem cell migration to bone marrow", "Hematopoietic stem cell proliferation", "Heme transport", "Hemidesmosome assembly", "Hemoglobin biosynthetic process", "Hemoglobin metabolic process", "Hemostasis", "Heparan sulfate proteoglycan biosynthetic process", "Heparan sulfate proteoglycan biosynthetic process enzymatic modification", "Heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process", "Heparan sulfate proteoglycan metabolic process", "Heparin biosynthetic process", "Heparin metabolic process", "Hepatic stellate cell activation", "Hepaticobiliary system development", "Hepatocyte apoptotic process", "Hepatocyte differentiation", "Hepatocyte growth factor receptor signaling pathway", "Hepoxilin metabolic process", "Heterochromatin organization", "Heterophilic cell cell adhesion via plasma membrane cell adhesion molecules", "Heterotypic cell cell adhesion", "High density lipoprotein particle assembly", "High density lipoprotein particle clearance", "High density lipoprotein particle remodeling", "Hindbrain development", "Hindbrain maturation", "Hindbrain morphogenesis", "Hindbrain radial glia guided cell migration", "Hindlimb morphogenesis", "Hippo signaling", "Hippocampus development", "His purkinje system development", "Histamine production involved in inflammatory response", "Histamine secretion", "Histamine transport", "Histidine metabolic process", "Histone arginine methylation", "Histone deacetylation", "Histone dephosphorylation", "Histone deubiquitination", "Histone exchange", "Histone h2a acetylation", "Histone h2a k119 monoubiquitination", "Histone h2a k63 linked ubiquitination", "Histone h2a monoubiquitination", "Histone h2a phosphorylation", "Histone h2a ubiquitination", "Histone h2b ubiquitination", "Histone h3 acetylation", "Histone h3 deacetylation", "Histone h3 k14 acetylation", "Histone h3 k27 demethylation", "Histone h3 k27 methylation", "Histone h3 k27 trimethylation", "Histone h3 k36 demethylation", "Histone h3 k36 methylation", "Histone h3 k36 trimethylation", "Histone h3 k4 demethylation", "Histone h3 k4 dimethylation", "Histone h3 k4 methylation", "Histone h3 k4 monomethylation", "Histone h3 k4 trimethylation", "Histone h3 k9 acetylation", "Histone h3 k9 demethylation", "Histone h3 k9 dimethylation", "Histone h3 k9 methylation", "Histone h3 k9 modification", "Histone h3 k9 trimethylation", "Histone h4 acetylation", "Histone h4 deacetylation", "Histone h4 k12 acetylation", "Histone h4 k16 acetylation", "Histone h4 k20 methylation", "Histone h4 k20 trimethylation", "Histone h4 k5 acetylation", "Histone h4 r3 methylation", "Histone lysine demethylation", "Histone methylation", "Histone modification", "Histone monoubiquitination", "Histone mrna catabolic process", "Histone mrna metabolic process", "Histone phosphorylation", "Histone serine phosphorylation", "Histone threonine phosphorylation", "Histone ubiquitination", "Homeostasis of number of cells", "Homeostasis of number of cells within a tissue", "Homeostatic process", "Homocysteine metabolic process", "Homologous chromosome pairing at meiosis", "Homologous chromosome segregation", "Homologous recombination", "Homophilic cell adhesion via plasma membrane adhesion molecules", "Homotypic cell cell adhesion", "Hormone biosynthetic process", "Hormone catabolic process", "Hormone mediated signaling pathway", "Hormone metabolic process", "Hormone transport", "Humoral immune response", "Humoral immune response mediated by circulating immunoglobulin", "Hyaluronan biosynthetic process", "Hyaluronan metabolic process", "Hydrogen peroxide biosynthetic process", "Hydrogen peroxide catabolic process", "Hydrogen peroxide metabolic process", "Hydrogen sulfide biosynthetic process", "Hydrogen sulfide metabolic process", "Hyperosmotic response", "Hyperosmotic salinity response", "Hypothalamus cell differentiation", "Hypothalamus cell migration", "Hypothalamus development", "Hypothalamus gonadotrophin releasing hormone neuron differentiation", "Hypotonic response", "Hypoxia inducible factor 1alpha signaling pathway", "I kappab kinase nf kappab signaling", "I kappab phosphorylation", "Icosanoid biosynthetic process", "Icosanoid metabolic process", "Icosanoid transport", "Immature b cell differentiation", "Immune complex clearance", "Immune effector process", "Immune response", "Immune response regulating cell surface receptor signaling pathway", "Immune response regulating signaling pathway", "Immune response to tumor cell", "Immune system development", "Immunoglobulin production", "Immunoglobulin production involved in immunoglobulin mediated immune response", "Immunoglobulin v d j recombination", "Immunological synapse formation", "Imp biosynthetic process", "Imp catabolic process", "Imp metabolic process", "Imp salvage", "Import across plasma membrane", "Import into cell", "Import into nucleus", "In utero embryonic development", "Inclusion body assembly", "Indolalkylamine metabolic process", "Indole containing compound biosynthetic process", "Indole containing compound metabolic process", "Inflammasome complex assembly", "Inflammatory cell apoptotic process", "Inflammatory response", "Inflammatory response to antigenic stimulus", "Inflammatory response to wounding", "Inhibitory postsynaptic potential", "Innate immune response", "Innate immune response activating signal transduction", "Innate immune response in mucosa", "Inner cell mass cell differentiation", "Inner cell mass cell proliferation", "Inner dynein arm assembly", "Inner ear auditory receptor cell differentiation", "Inner ear morphogenesis", "Inner ear receptor cell development", "Inner ear receptor cell stereocilium organization", "Inner mitochondrial membrane organization", "Innervation", "Inorganic anion transmembrane transport", "Inorganic anion transport", "Inorganic ion import across plasma membrane", "Inorganic ion transmembrane transport", "Inosine metabolic process", "Inositol lipid mediated signaling", "Inositol metabolic process", "Inositol phosphate catabolic process", "Inositol phosphate mediated signaling", "Inositol phosphate metabolic process", "Inositol trisphosphate metabolic process", "Insulin like growth factor receptor signaling pathway", "Insulin metabolic process", "Insulin processing", "Insulin receptor signaling pathway", "Insulin secretion", "Insulin secretion involved in cellular response to glucose stimulus", "Integrated stress response signaling", "Integrin activation", "Integrin mediated signaling pathway", "Intercellular transport", "Interferon alpha production", "Interferon beta production", "Interferon gamma mediated signaling pathway", "Interferon gamma production", "Interleukin 1 alpha production", "Interleukin 1 mediated signaling pathway", "Interleukin 1 production", "Interleukin 10 production", "Interleukin 12 production", "Interleukin 13 production", "Interleukin 17 production", "Interleukin 18 mediated signaling pathway", "Interleukin 18 production", "Interleukin 2 production", "Interleukin 23 production", "Interleukin 27 mediated signaling pathway", "Interleukin 4 production", "Interleukin 6 mediated signaling pathway", "Interleukin 6 production", "Interleukin 8 production", "Intermediate filament based process", "Intermediate filament bundle assembly", "Intermediate filament organization", "Intermembrane lipid transfer", "Interstrand cross link repair", "Intestinal absorption", "Intestinal epithelial cell development", "Intestinal epithelial cell differentiation", "Intestinal hexose absorption", "Intestinal lipid absorption", "Intra golgi vesicle mediated transport", "Intracellular distribution of mitochondria", "Intracellular estrogen receptor signaling pathway", "Intracellular lipid transport", "Intracellular mrna localization", "Intracellular protein transmembrane transport", "Intracellular protein transport", "Intracellular receptor signaling pathway", "Intracellular sterol transport", "Intracellular transport", "Intracellular transport of virus", "Intraciliary retrograde transport", "Intraciliary transport", "Intraciliary transport involved in cilium assembly", "Intrinsic apoptotic signaling pathway", "Intrinsic apoptotic signaling pathway by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to dna damage", "Intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress", "Intrinsic apoptotic signaling pathway in response to hydrogen peroxide", "Intrinsic apoptotic signaling pathway in response to hypoxia", "Intrinsic apoptotic signaling pathway in response to osmotic stress", "Intrinsic apoptotic signaling pathway in response to oxidative stress", "Ion homeostasis", "Ion transmembrane transport", "Ion transport", "Ire1 mediated unfolded protein response", "Ires dependent viral translational initiation", "Iris morphogenesis", "Iron coordination entity transport", "Iron import into cell", "Iron ion homeostasis", "Iron ion transmembrane transport", "Iron ion transport", "Iron sulfur cluster assembly", "Isocitrate metabolic process", "Isoleucine metabolic process", "Isopentenyl diphosphate biosynthetic process", "Isoprenoid biosynthetic process", "Isoprenoid metabolic process", "Isotype switching to iga isotypes", "Isotype switching to igg isotypes", "Jnk cascade", "Keratan sulfate metabolic process", "Keratinization", "Keratinocyte development", "Keratinocyte differentiation", "Keratinocyte migration", "Keratinocyte proliferation", "Ketone biosynthetic process", "Ketone body biosynthetic process", "Ketone body metabolic process", "Ketone catabolic process", "Kidney epithelium development", "Kidney mesenchyme development", "Kidney morphogenesis", "Killing by host of symbiont cells", "Killing of cells of another organism", "Kinetochore assembly", "Kinetochore organization", "Kynurenine metabolic process", "L alanine transport", "L alpha amino acid transmembrane transport", "L amino acid transport", "L arginine import across plasma membrane", "L arginine transmembrane transport", "L ascorbic acid metabolic process", "L aspartate transmembrane transport", "L glutamate import across plasma membrane", "L glutamate transmembrane transport", "L histidine transmembrane transport", "L kynurenine metabolic process", "L lysine transmembrane transport", "L methionine salvage from methylthioadenosine", "L phenylalanine metabolic process", "L proline biosynthetic process", "L serine biosynthetic process", "L serine catabolic process", "L serine metabolic process", "L serine transport", "Labyrinthine layer blood vessel development", "Labyrinthine layer development", "Labyrinthine layer morphogenesis", "Lacrimal gland development", "Lactate metabolic process", "Lactate transmembrane transport", "Lactation", "Lamellipodium assembly", "Lamellipodium morphogenesis", "Lamellipodium organization", "Late endosome to golgi transport", "Late endosome to lysosome transport", "Late endosome to vacuole transport", "Late endosome to vacuole transport via multivesicular body sorting pathway", "Late nucleophagy", "Lateral ventricle development", "Layer formation in cerebral cortex", "Learning", "Left right axis specification", "Left right pattern formation", "Lens development in camera type eye", "Lens fiber cell development", "Lens fiber cell differentiation", "Lens morphogenesis in camera type eye", "Leptin mediated signaling pathway", "Leucine catabolic process", "Leucine import across plasma membrane", "Leucine metabolic process", "Leucine transport", "Leukocyte adhesion to vascular endothelial cell", "Leukocyte aggregation", "Leukocyte apoptotic process", "Leukocyte cell cell adhesion", "Leukocyte chemotaxis", "Leukocyte degranulation", "Leukocyte differentiation", "Leukocyte homeostasis", "Leukocyte mediated cytotoxicity", "Leukocyte mediated immunity", "Leukocyte migration", "Leukocyte migration involved in inflammatory response", "Leukocyte proliferation", "Leukocyte tethering or rolling", "Leukotriene b4 metabolic process", "Leukotriene biosynthetic process", "Leukotriene metabolic process", "Leukotriene transport", "Leydig cell differentiation", "Ligand gated ion channel signaling pathway", "Limb joint morphogenesis", "Limbic system development", "Linoleic acid metabolic process", "Lipid biosynthetic process", "Lipid catabolic process", "Lipid digestion", "Lipid droplet formation", "Lipid droplet organization", "Lipid export from cell", "Lipid glycosylation", "Lipid homeostasis", "Lipid import into cell", "Lipid localization", "Lipid metabolic process", "Lipid modification", "Lipid oxidation", "Lipid phosphorylation", "Lipid storage", "Lipid translocation", "Lipid transport across blood brain barrier", "Lipophagy", "Lipopolysaccharide mediated signaling pathway", "Lipoprotein biosynthetic process", "Lipoprotein catabolic process", "Lipoprotein localization", "Lipoprotein metabolic process", "Liposaccharide metabolic process", "Lipoxin metabolic process", "Liver morphogenesis", "Liver regeneration", "Localization within membrane", "Locomotion", "Locomotion involved in locomotory behavior", "Locomotor rhythm", "Locomotory behavior", "Locomotory exploration behavior", "Long chain fatty acid biosynthetic process", "Long chain fatty acid import across plasma membrane", "Long chain fatty acid metabolic process", "Long chain fatty acid transport", "Long chain fatty acyl coa biosynthetic process", "Long chain fatty acyl coa metabolic process", "Long term memory", "Long term synaptic depression", "Long term synaptic potentiation", "Low density lipoprotein particle clearance", "Low density lipoprotein receptor particle metabolic process", "Lung alveolus development", "Lung associated mesenchyme development", "Lung cell differentiation", "Lung epithelium development", "Lung growth", "Lung lobe development", "Lung morphogenesis", "Lung saccule development", "Lung secretory cell differentiation", "Luteinization", "Luteinizing hormone secretion", "Luteolysis", "Lymphocyte activation", "Lymphocyte activation involved in immune response", "Lymphocyte aggregation", "Lymphocyte anergy", "Lymphocyte apoptotic process", "Lymphocyte chemotaxis", "Lymphocyte costimulation", "Lymphocyte homeostasis", "Lymphocyte mediated immunity", "Lymphocyte migration", "Lymphocyte migration into lymphoid organs", "Lymphoid progenitor cell differentiation", "Lysine catabolic process", "Lysine metabolic process", "Lysosomal lumen acidification", "Lysosomal membrane organization", "Lysosomal microautophagy", "Lysosomal protein catabolic process", "Lysosomal transport", "Lytic vacuole organization", "Macroautophagy", "Macromolecule catabolic process", "Macromolecule deacylation", "Macromolecule depalmitoylation", "Macrophage activation", "Macrophage apoptotic process", "Macrophage chemotaxis", "Macrophage cytokine production", "Macrophage differentiation", "Macrophage inflammatory protein 1 alpha production", "Macrophage migration", "Macrophage proliferation", "Macropinocytosis", "Magnesium ion homeostasis", "Magnesium ion transport", "Maintenance of animal organ identity", "Maintenance of apical basal cell polarity", "Maintenance of blood brain barrier", "Maintenance of cell number", "Maintenance of cell polarity", "Maintenance of centrosome location", "Maintenance of dna methylation", "Maintenance of dna repeat elements", "Maintenance of gastrointestinal epithelium", "Maintenance of lens transparency", "Maintenance of location", "Maintenance of location in cell", "Maintenance of organelle location", "Maintenance of postsynaptic specialization structure", "Maintenance of presynaptic active zone structure", "Maintenance of protein localization in endoplasmic reticulum", "Maintenance of protein localization in organelle", "Maintenance of protein location", "Maintenance of protein location in cell", "Maintenance of protein location in mitochondrion", "Maintenance of protein location in nucleus", "Maintenance of sister chromatid cohesion", "Maintenance of synapse structure", "Malate metabolic process", "Male gamete generation", "Male genitalia development", "Male mating behavior", "Male meiosis i", "Male meiotic nuclear division", "Male sex determination", "Male sex differentiation", "Malonyl coa metabolic process", "Mammalian oogenesis stage", "Mammary gland alveolus development", "Mammary gland branching involved in pregnancy", "Mammary gland development", "Mammary gland duct morphogenesis", "Mammary gland epithelial cell differentiation", "Mammary gland epithelial cell proliferation", "Mammary gland epithelium development", "Mammary gland involution", "Mammary gland morphogenesis", "Manganese ion transmembrane transport", "Manganese ion transport", "Mannose metabolic process", "Mannosylation", "Mapk cascade", "Marginal zone b cell differentiation", "Mast cell activation", "Mast cell activation involved in immune response", "Mast cell cytokine production", "Maternal placenta development", "Maternal process involved in female pregnancy", "Mating", "Mating behavior", "Maturation of 5 8s rrna", "Maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of lsu rrna", "Maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Maturation of ssu rrna", "Maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna", "Mature b cell differentiation", "Mature ribosome assembly", "Mda 5 signaling pathway", "Mechanoreceptor differentiation", "Mechanosensory behavior", "Medium chain fatty acid biosynthetic process", "Medium chain fatty acid catabolic process", "Medium chain fatty acid metabolic process", "Medium chain fatty acyl coa metabolic process", "Megakaryocyte development", "Megakaryocyte differentiation", "Meiosis i cell cycle process", "Meiosis ii cell cycle process", "Meiotic cell cycle", "Meiotic cell cycle checkpoint signaling", "Meiotic cell cycle phase transition", "Meiotic cell cycle process", "Meiotic chromosome condensation", "Meiotic chromosome segregation", "Meiotic chromosome separation", "Meiotic cytokinesis", "Meiotic dna double strand break formation", "Meiotic sister chromatid cohesion centromeric", "Meiotic spindle assembly", "Meiotic spindle organization", "Melanocyte differentiation", "Melanosome assembly", "Membrane biogenesis", "Membrane depolarization", "Membrane depolarization during action potential", "Membrane depolarization during cardiac muscle cell action potential", "Membrane disassembly", "Membrane docking", "Membrane fission", "Membrane fusion", "Membrane hyperpolarization", "Membrane invagination", "Membrane lipid biosynthetic process", "Membrane lipid catabolic process", "Membrane lipid metabolic process", "Membrane organization", "Membrane protein ectodomain proteolysis", "Membrane protein intracellular domain proteolysis", "Membrane protein proteolysis", "Membrane raft assembly", "Membrane raft localization", "Membrane raft organization", "Membrane repolarization", "Membrane repolarization during action potential", "Membrane repolarization during atrial cardiac muscle cell action potential", "Membrane repolarization during cardiac muscle cell action potential", "Membrane to membrane docking", "Membranous septum morphogenesis", "Memory", "Menaquinone metabolic process", "Mesangial cell development", "Mesangial cell differentiation", "Mesenchymal cell development", "Mesenchymal cell differentiation", "Mesenchymal cell differentiation involved in kidney development", "Mesenchymal cell proliferation", "Mesenchymal cell proliferation involved in lung development", "Mesenchymal stem cell differentiation", "Mesenchymal stem cell proliferation", "Mesenchymal to epithelial transition", "Mesenchymal to epithelial transition involved in metanephros morphogenesis", "Mesenchyme development", "Mesenchyme morphogenesis", "Mesoderm development", "Mesoderm morphogenesis", "Mesodermal cell differentiation", "Mesonephric duct development", "Mesonephric tubule formation", "Mesonephric tubule morphogenesis", "Mesonephros development", "Metal ion export", "Metal ion homeostasis", "Metal ion transport", "Metanephric collecting duct development", "Metanephric epithelium development", "Metanephric glomerulus development", "Metanephric glomerulus vasculature development", "Metanephric mesenchymal cell differentiation", "Metanephric mesenchyme development", "Metanephric nephron development", "Metanephric nephron morphogenesis", "Metanephric nephron tubule epithelial cell differentiation", "Metanephric part of ureteric bud development", "Metanephric renal vesicle morphogenesis", "Metanephric tubule development", "Metanephros development", "Metanephros morphogenesis", "Metaphase anaphase transition of cell cycle", "Metaphase plate congression", "Metencephalon development", "Methionine biosynthetic process", "Methionine metabolic process", "Methylation", "Methylglyoxal metabolic process", "Methylguanosine cap decapping", "Mhc class i biosynthetic process", "Mhc class ii biosynthetic process", "Microglia differentiation", "Microglial cell activation", "Microglial cell proliferation", "Microtubule anchoring", "Microtubule anchoring at centrosome", "Microtubule anchoring at microtubule organizing center", "Microtubule based movement", "Microtubule based process", "Microtubule based transport", "Microtubule bundle formation", "Microtubule cytoskeleton organization", "Microtubule cytoskeleton organization involved in mitosis", "Microtubule depolymerization", "Microtubule nucleation", "Microtubule organizing center localization", "Microtubule organizing center organization", "Microtubule polymerization", "Microtubule polymerization or depolymerization", "Microtubule severing", "Microvillus assembly", "Microvillus organization", "Midbody abscission", "Midbrain development", "Midbrain dopaminergic neuron differentiation", "Middle ear morphogenesis", "Midgut development", "Minus end directed organelle transport along microtubule", "Mirna catabolic process", "Mirna loading onto risc involved in gene silencing by mirna", "Mirna metabolic process", "Mismatch repair", "Mitochondrial acetyl coa biosynthetic process from pyruvate", "Mitochondrial adp transmembrane transport", "Mitochondrial atp synthesis coupled proton transport", "Mitochondrial calcium ion homeostasis", "Mitochondrial calcium ion transmembrane transport", "Mitochondrial cytochrome c oxidase assembly", "Mitochondrial depolarization", "Mitochondrial dna metabolic process", "Mitochondrial dna repair", "Mitochondrial dna replication", "Mitochondrial electron transport cytochrome c to oxygen", "Mitochondrial electron transport nadh to ubiquinone", "Mitochondrial electron transport ubiquinol to cytochrome c", "Mitochondrial fission", "Mitochondrial fragmentation involved in apoptotic process", "Mitochondrial fusion", "Mitochondrial gene expression", "Mitochondrial genome maintenance", "Mitochondrial membrane organization", "Mitochondrial outer membrane permeabilization", "Mitochondrial outer membrane permeabilization involved in programmed cell death", "Mitochondrial protein catabolic process", "Mitochondrial protein processing", "Mitochondrial proton transporting atp synthase complex assembly", "Mitochondrial respirasome assembly", "Mitochondrial respiratory chain complex assembly", "Mitochondrial ribosome assembly", "Mitochondrial rna 3 end processing", "Mitochondrial rna catabolic process", "Mitochondrial rna metabolic process", "Mitochondrial rna modification", "Mitochondrial rna processing", "Mitochondrial transcription", "Mitochondrial translation", "Mitochondrial translational elongation", "Mitochondrial transmembrane transport", "Mitochondrial transport", "Mitochondrial trna processing", "Mitochondrion distribution", "Mitochondrion endoplasmic reticulum membrane tethering", "Mitochondrion localization", "Mitochondrion morphogenesis", "Mitochondrion organization", "Mitophagy", "Mitotic cell cycle", "Mitotic cell cycle checkpoint signaling", "Mitotic cell cycle phase transition", "Mitotic cell cycle process", "Mitotic chromosome condensation", "Mitotic cytokinesis", "Mitotic cytokinetic process", "Mitotic dna integrity checkpoint signaling", "Mitotic dna replication", "Mitotic dna replication checkpoint signaling", "Mitotic g1 s transition checkpoint signaling", "Mitotic g2 dna damage checkpoint signaling", "Mitotic g2 m transition checkpoint", "Mitotic intra s dna damage checkpoint signaling", "Mitotic metaphase plate congression", "Mitotic nuclear division", "Mitotic nuclear membrane disassembly", "Mitotic nuclear membrane organization", "Mitotic recombination", "Mitotic sister chromatid cohesion", "Mitotic sister chromatid segregation", "Mitotic spindle assembly", "Mitotic spindle midzone assembly", "Mitotic spindle organization", "Modification dependent macromolecule catabolic process", "Modification of postsynaptic actin cytoskeleton", "Modification of postsynaptic structure", "Modification of synaptic structure", "Modified amino acid transport", "Modulation by host of symbiont catalytic activity", "Modulation by host of symbiont process", "Modulation by host of viral genome replication", "Modulation by host of viral process", "Modulation of age related behavioral decline", "Modulation of excitatory postsynaptic potential", "Molting cycle", "Monoacylglycerol catabolic process", "Monoacylglycerol metabolic process", "Monoamine transport", "Monocarboxylic acid biosynthetic process", "Monocarboxylic acid catabolic process", "Monocarboxylic acid metabolic process", "Monocarboxylic acid transport", "Monocyte chemotactic protein 1 production", "Monocyte chemotaxis", "Monocyte differentiation", "Monocyte extravasation", "Mononuclear cell differentiation", "Mononuclear cell migration", "Monosaccharide biosynthetic process", "Monosaccharide catabolic process", "Monosaccharide metabolic process", "Monoubiquitinated protein deubiquitination", "Monovalent inorganic anion homeostasis", "Monovalent inorganic cation homeostasis", "Morphogenesis of a branching structure", "Morphogenesis of a polarized epithelium", "Morphogenesis of an endothelium", "Morphogenesis of an epithelial bud", "Morphogenesis of an epithelial fold", "Morphogenesis of an epithelial sheet", "Morphogenesis of an epithelium", "Morphogenesis of embryonic epithelium", "Motile cilium assembly", "Motor behavior", "Motor neuron apoptotic process", "Motor neuron axon guidance", "Motor neuron migration", "Mrna 3 end processing", "Mrna 3 end processing by stem loop binding and cleavage", "Mrna 3 splice site recognition", "Mrna 5 splice site recognition", "Mrna alternative polyadenylation", "Mrna catabolic process", "Mrna cis splicing via spliceosome", "Mrna cleavage", "Mrna cleavage involved in mrna processing", "Mrna destabilization mediated gene silencing", "Mrna export from nucleus", "Mrna metabolic process", "Mrna methylation", "Mrna modification", "Mrna processing", "Mrna pseudouridine synthesis", "Mrna splice site selection", "Mrna transcription", "Mrna transport", "Mucopolysaccharide metabolic process", "Mucosa associated lymphoid tissue development", "Mucus secretion", "Multi multicellular organism process", "Multi organism reproductive process", "Multicellular organism aging", "Multicellular organism growth", "Multicellular organism reproduction", "Multicellular organismal homeostasis", "Multicellular organismal movement", "Multicellular organismal response to stress", "Multicellular organismal signaling", "Multinuclear osteoclast differentiation", "Multivesicular body organization", "Multivesicular body sorting pathway", "Muscle adaptation", "Muscle cell apoptotic process", "Muscle cell cellular homeostasis", "Muscle cell development", "Muscle cell differentiation", "Muscle cell migration", "Muscle cell proliferation", "Muscle contraction", "Muscle hypertrophy", "Muscle hypertrophy in response to stress", "Muscle organ development", "Muscle organ morphogenesis", "Muscle structure development", "Muscle system process", "Muscle tissue development", "Myd88 dependent toll like receptor signaling pathway", "Myd88 independent toll like receptor signaling pathway", "Myelin assembly", "Myelin maintenance", "Myeloid cell activation involved in immune response", "Myeloid cell apoptotic process", "Myeloid cell development", "Myeloid cell differentiation", "Myeloid cell homeostasis", "Myeloid dendritic cell activation", "Myeloid dendritic cell cytokine production", "Myeloid dendritic cell differentiation", "Myeloid leukocyte activation", "Myeloid leukocyte cytokine production", "Myeloid leukocyte differentiation", "Myeloid leukocyte mediated immunity", "Myeloid leukocyte migration", "Myeloid progenitor cell differentiation", "Myoblast differentiation", "Myoblast fusion", "Myoblast migration", "Myoblast proliferation", "Myofibroblast differentiation", "Myosin filament organization", "Myotube cell development", "Myotube differentiation", "N acetylglucosamine metabolic process", "N acetylneuraminate catabolic process", "N acetylneuraminate metabolic process", "N acylethanolamine metabolic process", "N glycan processing", "N terminal peptidyl methionine acetylation", "N terminal protein amino acid acetylation", "N terminal protein amino acid modification", "N terminal protein lipidation", "Nad biosynthesis via nicotinamide riboside salvage pathway", "Nad metabolic process", "Nadh dehydrogenase complex assembly", "Nadh metabolic process", "Nadh oxidation", "Nadh regeneration", "Nadp metabolic process", "Nadph regeneration", "Natural killer cell activation", "Natural killer cell activation involved in immune response", "Natural killer cell cytokine production", "Natural killer cell degranulation", "Natural killer cell differentiation", "Natural killer cell mediated immunity", "Ncrna 3 end processing", "Ncrna catabolic process", "Ncrna export from nucleus", "Ncrna metabolic process", "Ncrna processing", "Ncrna transcription", "Necroptotic signaling pathway", "Necrotic cell death", "Negative chemotaxis", "Negative regulation by host of viral genome replication", "Negative regulation by host of viral process", "Negative regulation by host of viral transcription", "Negative regulation of actin filament bundle assembly", "Negative regulation of actin filament depolymerization", "Negative regulation of actin filament polymerization", "Negative regulation of actin nucleation", "Negative regulation of activated t cell proliferation", "Negative regulation of activin receptor signaling pathway", "Negative regulation of adaptive immune response", "Negative regulation of adenylate cyclase activating adrenergic receptor signaling pathway", "Negative regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Negative regulation of adenylate cyclase activity", "Negative regulation of alcohol biosynthetic process", "Negative regulation of alpha beta t cell activation", "Negative regulation of alpha beta t cell differentiation", "Negative regulation of alpha beta t cell proliferation", "Negative regulation of amine transport", "Negative regulation of amino acid transport", "Negative regulation of amyloid beta clearance", "Negative regulation of amyloid fibril formation", "Negative regulation of amyloid precursor protein biosynthetic process", "Negative regulation of amyloid precursor protein catabolic process", "Negative regulation of androgen receptor signaling pathway", "Negative regulation of anion transmembrane transport", "Negative regulation of anion transport", "Negative regulation of anoikis", "Negative regulation of antigen receptor mediated signaling pathway", "Negative regulation of apoptotic signaling pathway", "Negative regulation of arp2 3 complex mediated actin nucleation", "Negative regulation of astrocyte activation", "Negative regulation of astrocyte differentiation", "Negative regulation of atp biosynthetic process", "Negative regulation of atp dependent activity", "Negative regulation of atp metabolic process", "Negative regulation of atpase coupled calcium transmembrane transporter activity", "Negative regulation of autophagosome assembly", "Negative regulation of autophagosome maturation", "Negative regulation of autophagy", "Negative regulation of autophagy of mitochondrion", "Negative regulation of axon extension", "Negative regulation of axon extension involved in axon guidance", "Negative regulation of axonogenesis", "Negative regulation of b cell activation", "Negative regulation of b cell apoptotic process", "Negative regulation of b cell differentiation", "Negative regulation of b cell mediated immunity", "Negative regulation of b cell proliferation", "Negative regulation of bicellular tight junction assembly", "Negative regulation of binding", "Negative regulation of biomineralization", "Negative regulation of biosynthetic process", "Negative regulation of blood circulation", "Negative regulation of blood pressure", "Negative regulation of blood vessel endothelial cell migration", "Negative regulation of bmp signaling pathway", "Negative regulation of bone mineralization", "Negative regulation of bone remodeling", "Negative regulation of calcineurin mediated signaling", "Negative regulation of calcium ion dependent exocytosis", "Negative regulation of calcium ion import", "Negative regulation of calcium ion transmembrane transport", "Negative regulation of calcium ion transport", "Negative regulation of calcium ion transport into cytosol", "Negative regulation of calcium mediated signaling", "Negative regulation of camp dependent protein kinase activity", "Negative regulation of canonical wnt signaling pathway", "Negative regulation of carbohydrate metabolic process", "Negative regulation of cardiac muscle adaptation", "Negative regulation of cardiac muscle contraction", "Negative regulation of cardiac muscle tissue growth", "Negative regulation of cartilage development", "Negative regulation of catabolic process", "Negative regulation of catalytic activity", "Negative regulation of catecholamine secretion", "Negative regulation of cation channel activity", "Negative regulation of cd4 positive alpha beta t cell activation", "Negative regulation of cd4 positive alpha beta t cell differentiation", "Negative regulation of cd4 positive alpha beta t cell proliferation", "Negative regulation of cell activation", "Negative regulation of cell adhesion", "Negative regulation of cell adhesion mediated by integrin", "Negative regulation of cell aging", "Negative regulation of cell cell adhesion", "Negative regulation of cell cell adhesion mediated by cadherin", "Negative regulation of cell cycle", "Negative regulation of cell cycle checkpoint", "Negative regulation of cell cycle g1 s phase transition", "Negative regulation of cell cycle g2 m phase transition", "Negative regulation of cell cycle phase transition", "Negative regulation of cell cycle process", "Negative regulation of cell death", "Negative regulation of cell development", "Negative regulation of cell differentiation", "Negative regulation of cell division", "Negative regulation of cell growth", "Negative regulation of cell growth involved in cardiac muscle cell development", "Negative regulation of cell junction assembly", "Negative regulation of cell killing", "Negative regulation of cell matrix adhesion", "Negative regulation of cell morphogenesis involved in differentiation", "Negative regulation of cell population proliferation", "Negative regulation of cell projection organization", "Negative regulation of cell size", "Negative regulation of cell substrate adhesion", "Negative regulation of cell substrate junction organization", "Negative regulation of cell volume", "Negative regulation of cellular amide metabolic process", "Negative regulation of cellular amine metabolic process", "Negative regulation of cellular catabolic process", "Negative regulation of cellular component organization", "Negative regulation of cellular extravasation", "Negative regulation of cellular macromolecule biosynthetic process", "Negative regulation of cellular protein catabolic process", "Negative regulation of cellular respiration", "Negative regulation of cellular response to growth factor stimulus", "Negative regulation of cellular response to hypoxia", "Negative regulation of cellular response to insulin stimulus", "Negative regulation of cellular response to vascular endothelial growth factor stimulus", "Negative regulation of cellular senescence", "Negative regulation of centriole replication", "Negative regulation of centrosome duplication", "Negative regulation of chemokine c c motif ligand 5 production", "Negative regulation of chemokine mediated signaling pathway", "Negative regulation of chemokine production", "Negative regulation of chemotaxis", "Negative regulation of cholesterol metabolic process", "Negative regulation of chondrocyte differentiation", "Negative regulation of chromatin binding", "Negative regulation of chromatin organization", "Negative regulation of chromosome organization", "Negative regulation of cilium assembly", "Negative regulation of circadian rhythm", "Negative regulation of coagulation", "Negative regulation of cold induced thermogenesis", "Negative regulation of collateral sprouting", "Negative regulation of cyclic nucleotide phosphodiesterase activity", "Negative regulation of cyclin dependent protein serine threonine kinase activity", "Negative regulation of cysteine type endopeptidase activity", "Negative regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Negative regulation of cytokine production", "Negative regulation of cytokine production involved in immune response", "Negative regulation of cytokine production involved in inflammatory response", "Negative regulation of cytokinesis", "Negative regulation of cytoplasmic translation", "Negative regulation of cytoskeleton organization", "Negative regulation of cytosolic calcium ion concentration", "Negative regulation of defense response", "Negative regulation of defense response to bacterium", "Negative regulation of defense response to virus", "Negative regulation of delayed rectifier potassium channel activity", "Negative regulation of dendrite development", "Negative regulation of dendrite morphogenesis", "Negative regulation of dendritic spine development", "Negative regulation of dendritic spine morphogenesis", "Negative regulation of dephosphorylation", "Negative regulation of developmental growth", "Negative regulation of developmental process", "Negative regulation of digestive system process", "Negative regulation of dna binding", "Negative regulation of dna binding transcription factor activity", "Negative regulation of dna biosynthetic process", "Negative regulation of dna damage checkpoint", "Negative regulation of dna damage response signal transduction by p53 class mediator", "Negative regulation of dna dependent dna replication", "Negative regulation of dna metabolic process", "Negative regulation of dna recombination", "Negative regulation of dna repair", "Negative regulation of dna replication", "Negative regulation of dna templated transcription elongation", "Negative regulation of dna templated transcription initiation", "Negative regulation of dopamine secretion", "Negative regulation of double strand break repair via homologous recombination", "Negative regulation of double strand break repair via nonhomologous end joining", "Negative regulation of endocytosis", "Negative regulation of endoplasmic reticulum calcium ion concentration", "Negative regulation of endoplasmic reticulum stress induced eif2 alpha phosphorylation", "Negative regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Negative regulation of endoplasmic reticulum unfolded protein response", "Negative regulation of endothelial cell apoptotic process", "Negative regulation of endothelial cell proliferation", "Negative regulation of epidermal growth factor activated receptor activity", "Negative regulation of epidermis development", "Negative regulation of epithelial cell apoptotic process", "Negative regulation of epithelial cell differentiation", "Negative regulation of epithelial cell migration", "Negative regulation of epithelial cell proliferation", "Negative regulation of erad pathway", "Negative regulation of erbb signaling pathway", "Negative regulation of erk1 and erk2 cascade", "Negative regulation of erythrocyte differentiation", "Negative regulation of establishment of protein localization", "Negative regulation of establishment of protein localization to mitochondrion", "Negative regulation of excitatory postsynaptic potential", "Negative regulation of execution phase of apoptosis", "Negative regulation of exocytosis", "Negative regulation of extrinsic apoptotic signaling pathway", "Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Negative regulation of fat cell differentiation", "Negative regulation of fatty acid beta oxidation", "Negative regulation of fatty acid biosynthetic process", "Negative regulation of fatty acid metabolic process", "Negative regulation of fatty acid oxidation", "Negative regulation of fatty acid transport", "Negative regulation of fibroblast apoptotic process", "Negative regulation of fibroblast migration", "Negative regulation of fibroblast proliferation", "Negative regulation of filopodium assembly", "Negative regulation of g protein coupled receptor signaling pathway", "Negative regulation of gene expression", "Negative regulation of gene expression epigenetic", "Negative regulation of glial cell apoptotic process", "Negative regulation of glial cell differentiation", "Negative regulation of glial cell proliferation", "Negative regulation of gliogenesis", "Negative regulation of glucocorticoid metabolic process", "Negative regulation of gluconeogenesis", "Negative regulation of glucose import", "Negative regulation of glucose transmembrane transport", "Negative regulation of glycogen metabolic process", "Negative regulation of glycolytic process", "Negative regulation of glycoprotein metabolic process", "Negative regulation of golgi to plasma membrane protein transport", "Negative regulation of granulocyte chemotaxis", "Negative regulation of growth", "Negative regulation of gtpase activity", "Negative regulation of guanyl nucleotide exchange factor activity", "Negative regulation of heart rate", "Negative regulation of helicase activity", "Negative regulation of hematopoietic progenitor cell differentiation", "Negative regulation of hemopoiesis", "Negative regulation of high voltage gated calcium channel activity", "Negative regulation of hippo signaling", "Negative regulation of histone acetylation", "Negative regulation of histone deacetylation", "Negative regulation of histone h3 k27 methylation", "Negative regulation of histone h3 k4 methylation", "Negative regulation of histone h3 k9 methylation", "Negative regulation of histone h3 k9 trimethylation", "Negative regulation of histone h4 acetylation", "Negative regulation of histone methylation", "Negative regulation of histone modification", "Negative regulation of histone phosphorylation", "Negative regulation of homotypic cell cell adhesion", "Negative regulation of hormone biosynthetic process", "Negative regulation of hormone metabolic process", "Negative regulation of hormone secretion", "Negative regulation of hydrogen peroxide mediated programmed cell death", "Negative regulation of hydrolase activity", "Negative regulation of hypoxia induced intrinsic apoptotic signaling pathway", "Negative regulation of i kappab kinase nf kappab signaling", "Negative regulation of immune effector process", "Negative regulation of immune response", "Negative regulation of immune system process", "Negative regulation of immunoglobulin production", "Negative regulation of inclusion body assembly", "Negative regulation of inflammatory response", "Negative regulation of inflammatory response to antigenic stimulus", "Negative regulation of innate immune response", "Negative regulation of insulin secretion involved in cellular response to glucose stimulus", "Negative regulation of interferon beta production", "Negative regulation of interferon gamma production", "Negative regulation of interleukin 1 beta production", "Negative regulation of interleukin 1 production", "Negative regulation of interleukin 12 production", "Negative regulation of interleukin 13 production", "Negative regulation of interleukin 17 production", "Negative regulation of interleukin 2 production", "Negative regulation of interleukin 6 production", "Negative regulation of interleukin 8 production", "Negative regulation of intracellular estrogen receptor signaling pathway", "Negative regulation of intracellular protein transport", "Negative regulation of intracellular signal transduction", "Negative regulation of intracellular steroid hormone receptor signaling pathway", "Negative regulation of intracellular transport", "Negative regulation of intrinsic apoptotic signaling pathway", "Negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Negative regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Negative regulation of ion transmembrane transport", "Negative regulation of ion transmembrane transporter activity", "Negative regulation of ion transport", "Negative regulation of ire1 mediated unfolded protein response", "Negative regulation of isotype switching", "Negative regulation of jnk cascade", "Negative regulation of jun kinase activity", "Negative regulation of keratinocyte differentiation", "Negative regulation of keratinocyte proliferation", "Negative regulation of kidney development", "Negative regulation of kinase activity", "Negative regulation of lamellipodium assembly", "Negative regulation of lamellipodium organization", "Negative regulation of leukocyte apoptotic process", "Negative regulation of leukocyte cell cell adhesion", "Negative regulation of leukocyte chemotaxis", "Negative regulation of leukocyte degranulation", "Negative regulation of leukocyte mediated immunity", "Negative regulation of leukocyte migration", "Negative regulation of leukocyte proliferation", "Negative regulation of lipase activity", "Negative regulation of lipid biosynthetic process", "Negative regulation of lipid catabolic process", "Negative regulation of lipid kinase activity", "Negative regulation of lipid localization", "Negative regulation of lipid metabolic process", "Negative regulation of lipid storage", "Negative regulation of lipid transport", "Negative regulation of lipopolysaccharide mediated signaling pathway", "Negative regulation of lipoprotein lipase activity", "Negative regulation of lipoprotein metabolic process", "Negative regulation of lipoprotein particle clearance", "Negative regulation of locomotion", "Negative regulation of long term synaptic potentiation", "Negative regulation of low density lipoprotein particle clearance", "Negative regulation of low density lipoprotein receptor activity", "Negative regulation of lyase activity", "Negative regulation of lymphocyte activation", "Negative regulation of lymphocyte apoptotic process", "Negative regulation of lymphocyte differentiation", "Negative regulation of lymphocyte mediated immunity", "Negative regulation of lymphocyte migration", "Negative regulation of macroautophagy", "Negative regulation of macrophage activation", "Negative regulation of macrophage chemotaxis", "Negative regulation of macrophage derived foam cell differentiation", "Negative regulation of macrophage migration", "Negative regulation of map kinase activity", "Negative regulation of mapk cascade", "Negative regulation of mast cell activation", "Negative regulation of mast cell activation involved in immune response", "Negative regulation of mast cell degranulation", "Negative regulation of megakaryocyte differentiation", "Negative regulation of meiotic cell cycle", "Negative regulation of meiotic nuclear division", "Negative regulation of membrane permeability", "Negative regulation of membrane potential", "Negative regulation of membrane protein ectodomain proteolysis", "Negative regulation of mesenchymal cell proliferation", "Negative regulation of metalloendopeptidase activity", "Negative regulation of metallopeptidase activity", "Negative regulation of metaphase anaphase transition of cell cycle", "Negative regulation of mhc class ii biosynthetic process", "Negative regulation of microglial cell activation", "Negative regulation of microtubule polymerization", "Negative regulation of microtubule polymerization or depolymerization", "Negative regulation of mirna transcription", "Negative regulation of mitochondrial fusion", "Negative regulation of mitochondrial membrane permeability", "Negative regulation of mitochondrial membrane permeability involved in apoptotic process", "Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Negative regulation of mitochondrion organization", "Negative regulation of mitophagy", "Negative regulation of mitotic cell cycle", "Negative regulation of mitotic cell cycle phase transition", "Negative regulation of molecular function", "Negative regulation of monocyte chemotactic protein 1 production", "Negative regulation of monocyte chemotaxis", "Negative regulation of monocyte differentiation", "Negative regulation of mononuclear cell migration", "Negative regulation of monooxygenase activity", "Negative regulation of mrna 3 end processing", "Negative regulation of mrna catabolic process", "Negative regulation of mrna metabolic process", "Negative regulation of mrna processing", "Negative regulation of mrna splicing via spliceosome", "Negative regulation of multicellular organism growth", "Negative regulation of multicellular organismal process", "Negative regulation of muscle adaptation", "Negative regulation of muscle cell apoptotic process", "Negative regulation of muscle cell differentiation", "Negative regulation of muscle contraction", "Negative regulation of muscle hypertrophy", "Negative regulation of muscle organ development", "Negative regulation of muscle tissue development", "Negative regulation of myelination", "Negative regulation of myeloid cell apoptotic process", "Negative regulation of myeloid cell differentiation", "Negative regulation of myeloid leukocyte differentiation", "Negative regulation of myeloid leukocyte mediated immunity", "Negative regulation of myoblast differentiation", "Negative regulation of myosin light chain phosphatase activity", "Negative regulation of myotube differentiation", "Negative regulation of natural killer cell activation", "Negative regulation of natural killer cell mediated immunity", "Negative regulation of necrotic cell death", "Negative regulation of nervous system development", "Negative regulation of nervous system process", "Negative regulation of neural precursor cell proliferation", "Negative regulation of neuroblast proliferation", "Negative regulation of neuroinflammatory response", "Negative regulation of neuron apoptotic process", "Negative regulation of neuron death", "Negative regulation of neuron differentiation", "Negative regulation of neuron migration", "Negative regulation of neuron projection development", "Negative regulation of neuron projection regeneration", "Negative regulation of neurotransmitter secretion", "Negative regulation of neurotransmitter transport", "Negative regulation of neutrophil activation", "Negative regulation of neutrophil migration", "Negative regulation of nf kappab transcription factor activity", "Negative regulation of nik nf kappab signaling", "Negative regulation of nitric oxide metabolic process", "Negative regulation of nitric oxide synthase activity", "Negative regulation of non canonical wnt signaling pathway", "Negative regulation of notch signaling pathway", "Negative regulation of nuclear division", "Negative regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Negative regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Negative regulation of nuclease activity", "Negative regulation of nucleobase containing compound metabolic process", "Negative regulation of nucleocytoplasmic transport", "Negative regulation of nucleotide biosynthetic process", "Negative regulation of nucleotide metabolic process", "Negative regulation of oligodendrocyte differentiation", "Negative regulation of organ growth", "Negative regulation of organelle assembly", "Negative regulation of organelle organization", "Negative regulation of organic acid transport", "Negative regulation of ossification", "Negative regulation of osteoblast differentiation", "Negative regulation of osteoblast proliferation", "Negative regulation of osteoclast differentiation", "Negative regulation of oxidative phosphorylation", "Negative regulation of oxidative stress induced cell death", "Negative regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Negative regulation of oxidative stress induced neuron death", "Negative regulation of oxidative stress induced neuron intrinsic apoptotic signaling pathway", "Negative regulation of oxidoreductase activity", "Negative regulation of p38mapk cascade", "Negative regulation of peptidase activity", "Negative regulation of peptide secretion", "Negative regulation of peptidyl cysteine s nitrosylation", "Negative regulation of peptidyl lysine acetylation", "Negative regulation of peptidyl serine phosphorylation", "Negative regulation of peptidyl threonine phosphorylation", "Negative regulation of peptidyl tyrosine phosphorylation", "Negative regulation of perk mediated unfolded protein response", "Negative regulation of phagocytosis", "Negative regulation of phosphatase activity", "Negative regulation of phosphatidylinositol 3 kinase signaling", "Negative regulation of phospholipase activity", "Negative regulation of phospholipid metabolic process", "Negative regulation of phosphoprotein phosphatase activity", "Negative regulation of phosphorus metabolic process", "Negative regulation of phosphorylation", "Negative regulation of plasma membrane bounded cell projection assembly", "Negative regulation of platelet activation", "Negative regulation of platelet derived growth factor receptor signaling pathway", "Negative regulation of posttranscriptional gene silencing", "Negative regulation of potassium ion transmembrane transport", "Negative regulation of potassium ion transport", "Negative regulation of production of mirnas involved in gene silencing by mirna", "Negative regulation of production of molecular mediator of immune response", "Negative regulation of programmed necrotic cell death", "Negative regulation of prostaglandin biosynthetic process", "Negative regulation of proteasomal protein catabolic process", "Negative regulation of proteasomal ubiquitin dependent protein catabolic process", "Negative regulation of protein acetylation", "Negative regulation of protein autophosphorylation", "Negative regulation of protein binding", "Negative regulation of protein catabolic process", "Negative regulation of protein containing complex assembly", "Negative regulation of protein containing complex disassembly", "Negative regulation of protein dephosphorylation", "Negative regulation of protein exit from endoplasmic reticulum", "Negative regulation of protein export from nucleus", "Negative regulation of protein import into nucleus", "Negative regulation of protein k63 linked ubiquitination", "Negative regulation of protein kinase activity by regulation of protein phosphorylation", "Negative regulation of protein kinase b signaling", "Negative regulation of protein localization", "Negative regulation of protein localization to cell periphery", "Negative regulation of protein localization to cell surface", "Negative regulation of protein localization to membrane", "Negative regulation of protein localization to microtubule", "Negative regulation of protein localization to nucleus", "Negative regulation of protein maturation", "Negative regulation of protein metabolic process", "Negative regulation of protein modification by small protein conjugation or removal", "Negative regulation of protein modification process", "Negative regulation of protein polymerization", "Negative regulation of protein polyubiquitination", "Negative regulation of protein secretion", "Negative regulation of protein serine threonine kinase activity", "Negative regulation of protein sumoylation", "Negative regulation of protein targeting to membrane", "Negative regulation of protein targeting to mitochondrion", "Negative regulation of protein tyrosine kinase activity", "Negative regulation of proteolysis", "Negative regulation of proteolysis involved in cellular protein catabolic process", "Negative regulation of reactive oxygen species biosynthetic process", "Negative regulation of reactive oxygen species metabolic process", "Negative regulation of receptor binding", "Negative regulation of receptor internalization", "Negative regulation of receptor mediated endocytosis", "Negative regulation of receptor recycling", "Negative regulation of receptor signaling pathway via jak stat", "Negative regulation of receptor signaling pathway via stat", "Negative regulation of regulated secretory pathway", "Negative regulation of release of cytochrome c from mitochondria", "Negative regulation of reproductive process", "Negative regulation of respiratory burst", "Negative regulation of respiratory burst involved in inflammatory response", "Negative regulation of response to biotic stimulus", "Negative regulation of response to cytokine stimulus", "Negative regulation of response to dna damage stimulus", "Negative regulation of response to endoplasmic reticulum stress", "Negative regulation of response to external stimulus", "Negative regulation of response to food", "Negative regulation of response to oxidative stress", "Negative regulation of response to reactive oxygen species", "Negative regulation of response to stimulus", "Negative regulation of response to wounding", "Negative regulation of retinoic acid receptor signaling pathway", "Negative regulation of rho protein signal transduction", "Negative regulation of ribosome biogenesis", "Negative regulation of rig i signaling pathway", "Negative regulation of rna catabolic process", "Negative regulation of rna splicing", "Negative regulation of ruffle assembly", "Negative regulation of ryanodine sensitive calcium release channel activity", "Negative regulation of schwann cell proliferation", "Negative regulation of secondary metabolite biosynthetic process", "Negative regulation of secretion", "Negative regulation of sequestering of triglyceride", "Negative regulation of signal transduction by p53 class mediator", "Negative regulation of signal transduction in absence of ligand", "Negative regulation of signaling", "Negative regulation of signaling receptor activity", "Negative regulation of single stranded viral rna replication via double stranded dna intermediate", "Negative regulation of sister chromatid cohesion", "Negative regulation of small gtpase mediated signal transduction", "Negative regulation of small molecule metabolic process", "Negative regulation of smooth muscle cell apoptotic process", "Negative regulation of smooth muscle cell differentiation", "Negative regulation of smooth muscle cell migration", "Negative regulation of smooth muscle cell proliferation", "Negative regulation of smoothened signaling pathway", "Negative regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Negative regulation of sodium ion transmembrane transport", "Negative regulation of sodium ion transport", "Negative regulation of sprouting angiogenesis", "Negative regulation of stem cell differentiation", "Negative regulation of steroid metabolic process", "Negative regulation of sterol transport", "Negative regulation of stress activated protein kinase signaling cascade", "Negative regulation of striated muscle cell apoptotic process", "Negative regulation of striated muscle cell differentiation", "Negative regulation of striated muscle contraction", "Negative regulation of supramolecular fiber organization", "Negative regulation of synapse assembly", "Negative regulation of synapse organization", "Negative regulation of synaptic transmission", "Negative regulation of synaptic transmission glutamatergic", "Negative regulation of synaptic vesicle exocytosis", "Negative regulation of systemic arterial blood pressure", "Negative regulation of t cell apoptotic process", "Negative regulation of t cell cytokine production", "Negative regulation of t cell differentiation", "Negative regulation of t cell mediated immunity", "Negative regulation of t cell proliferation", "Negative regulation of t cell receptor signaling pathway", "Negative regulation of t helper cell differentiation", "Negative regulation of telomerase activity", "Negative regulation of telomere capping", "Negative regulation of telomere maintenance", "Negative regulation of telomere maintenance via telomerase", "Negative regulation of telomere maintenance via telomere lengthening", "Negative regulation of thymocyte apoptotic process", "Negative regulation of tissue remodeling", "Negative regulation of toll like receptor signaling pathway", "Negative regulation of tor signaling", "Negative regulation of transcription by competitive promoter binding", "Negative regulation of transcription by rna polymerase i", "Negative regulation of transcription by rna polymerase ii", "Negative regulation of transcription from rna polymerase ii promoter in response to stress", "Negative regulation of transcription initiation from rna polymerase ii promoter", "Negative regulation of transcription regulatory region dna binding", "Negative regulation of transferase activity", "Negative regulation of transforming growth factor beta production", "Negative regulation of transforming growth factor beta receptor signaling pathway", "Negative regulation of transforming growth factor beta1 production", "Negative regulation of translational elongation", "Negative regulation of translational initiation", "Negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Negative regulation of transmembrane transport", "Negative regulation of transport", "Negative regulation of transporter activity", "Negative regulation of trophoblast cell migration", "Negative regulation of tubulin deacetylation", "Negative regulation of tumor necrosis factor superfamily cytokine production", "Negative regulation of type 2 immune response", "Negative regulation of type b pancreatic cell apoptotic process", "Negative regulation of type i interferon mediated signaling pathway", "Negative regulation of type i interferon production", "Negative regulation of tyrosine phosphorylation of stat protein", "Negative regulation of ubiquitin dependent protein catabolic process", "Negative regulation of ubiquitin protein ligase activity", "Negative regulation of ubiquitin protein transferase activity", "Negative regulation of vascular associated smooth muscle cell apoptotic process", "Negative regulation of vascular associated smooth muscle cell differentiation", "Negative regulation of vascular associated smooth muscle cell migration", "Negative regulation of vascular associated smooth muscle cell proliferation", "Negative regulation of vascular endothelial growth factor production", "Negative regulation of vascular endothelial growth factor receptor signaling pathway", "Negative regulation of vascular permeability", "Negative regulation of vascular wound healing", "Negative regulation of vasculature development", "Negative regulation of viral entry into host cell", "Negative regulation of viral genome replication", "Negative regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Negative regulation of viral life cycle", "Negative regulation of viral process", "Negative regulation of viral transcription", "Negative regulation of vitamin metabolic process", "Negative regulation of voltage gated calcium channel activity", "Negative regulation of voltage gated potassium channel activity", "Negative regulation of wnt signaling pathway", "Negative regulation of wound healing", "Negative t cell selection", "Nephric duct development", "Nephric duct morphogenesis", "Nephron development", "Nephron epithelium development", "Nephron morphogenesis", "Nephron tubule epithelial cell differentiation", "Nephron tubule formation", "Nerve development", "Nerve growth factor signaling pathway", "Nervous system process", "Nervous system process involved in regulation of systemic arterial blood pressure", "Neural crest cell differentiation", "Neural crest cell migration", "Neural crest cell migration involved in autonomic nervous system development", "Neural crest formation", "Neural nucleus development", "Neural plate development", "Neural plate morphogenesis", "Neural precursor cell proliferation", "Neural retina development", "Neural tube development", "Neural tube formation", "Neural tube patterning", "Neuroblast division", "Neuroblast proliferation", "Neuroendocrine cell differentiation", "Neuroepithelial cell differentiation", "Neurofilament cytoskeleton organization", "Neurogenesis", "Neuroinflammatory response", "Neuromuscular junction development", "Neuromuscular process", "Neuromuscular process controlling balance", "Neuromuscular process controlling posture", "Neuromuscular synaptic transmission", "Neuron apoptotic process", "Neuron cellular homeostasis", "Neuron death", "Neuron death in response to hydrogen peroxide", "Neuron death in response to oxidative stress", "Neuron development", "Neuron differentiation", "Neuron fate commitment", "Neuron fate determination", "Neuron intrinsic apoptotic signaling pathway in response to oxidative stress", "Neuron maturation", "Neuron migration", "Neuron projection arborization", "Neuron projection extension", "Neuron projection extension involved in neuron projection guidance", "Neuron projection guidance", "Neuron projection maintenance", "Neuron projection organization", "Neuron projection regeneration", "Neuron recognition", "Neuron remodeling", "Neuronal action potential", "Neuronal ion channel clustering", "Neuronal signal transduction", "Neuronal stem cell population maintenance", "Neuropeptide signaling pathway", "Neurotransmitter biosynthetic process", "Neurotransmitter catabolic process", "Neurotransmitter gated ion channel clustering", "Neurotransmitter metabolic process", "Neurotransmitter receptor internalization", "Neurotransmitter receptor localization to postsynaptic specialization membrane", "Neurotransmitter receptor transport", "Neurotransmitter receptor transport endosome to postsynaptic membrane", "Neurotransmitter receptor transport postsynaptic endosome to lysosome", "Neurotransmitter receptor transport to plasma membrane", "Neurotransmitter reuptake", "Neurotransmitter secretion", "Neurotransmitter transport", "Neurotransmitter uptake", "Neurotrophin production", "Neurotrophin signaling pathway", "Neurotrophin trk receptor signaling pathway", "Neutral amino acid transport", "Neutral lipid biosynthetic process", "Neutral lipid catabolic process", "Neutral lipid metabolic process", "Neutrophil activation involved in immune response", "Neutrophil apoptotic process", "Neutrophil chemotaxis", "Neutrophil clearance", "Neutrophil degranulation", "Neutrophil differentiation", "Neutrophil homeostasis", "Neutrophil mediated immunity", "Neutrophil migration", "Nik nf kappab signaling", "Nitric oxide mediated signal transduction", "Nitric oxide synthase biosynthetic process", "Nitrogen compound transport", "Nk t cell activation", "Nk t cell differentiation", "Nls bearing protein import into nucleus", "Non canonical wnt signaling pathway", "Non lytic viral release", "Non membrane bounded organelle assembly", "Non motile cilium assembly", "Nonribosomal peptide biosynthetic process", "Nose development", "Notch receptor processing", "Notch signaling involved in heart development", "Notch signaling pathway", "Nuclear body organization", "Nuclear chromosome segregation", "Nuclear envelope organization", "Nuclear export", "Nuclear membrane organization", "Nuclear membrane reassembly", "Nuclear migration", "Nuclear ncrna surveillance", "Nuclear pore complex assembly", "Nuclear pore organization", "Nuclear transcribed mrna catabolic process", "Nuclear transcribed mrna catabolic process deadenylation dependent decay", "Nuclear transcribed mrna catabolic process deadenylation independent decay", "Nuclear transcribed mrna catabolic process exonucleolytic", "Nuclear transcribed mrna catabolic process exonucleolytic 3 5", "Nuclear transcribed mrna catabolic process nonsense mediated decay", "Nuclear transcribed mrna poly a tail shortening", "Nuclear transport", "Nucleic acid phosphodiester bond hydrolysis", "Nucleobase biosynthetic process", "Nucleobase catabolic process", "Nucleobase containing compound transport", "Nucleobase containing small molecule biosynthetic process", "Nucleobase containing small molecule catabolic process", "Nucleobase containing small molecule interconversion", "Nucleobase containing small molecule metabolic process", "Nucleobase metabolic process", "Nucleobase transport", "Nucleolar chromatin organization", "Nucleolar large rrna transcription by rna polymerase i", "Nucleolus organization", "Nucleoside bisphosphate biosynthetic process", "Nucleoside bisphosphate catabolic process", "Nucleoside bisphosphate metabolic process", "Nucleoside catabolic process", "Nucleoside diphosphate biosynthetic process", "Nucleoside diphosphate catabolic process", "Nucleoside diphosphate metabolic process", "Nucleoside metabolic process", "Nucleoside monophosphate biosynthetic process", "Nucleoside monophosphate catabolic process", "Nucleoside monophosphate metabolic process", "Nucleoside monophosphate phosphorylation", "Nucleoside phosphate biosynthetic process", "Nucleoside phosphate catabolic process", "Nucleoside salvage", "Nucleoside transmembrane transport", "Nucleoside transport", "Nucleoside triphosphate biosynthetic process", "Nucleoside triphosphate catabolic process", "Nucleoside triphosphate metabolic process", "Nucleosome assembly", "Nucleosome mobilization", "Nucleosome organization", "Nucleosome positioning", "Nucleotide binding domain leucine rich repeat containing receptor signaling pathway", "Nucleotide binding oligomerization domain containing 2 signaling pathway", "Nucleotide excision repair", "Nucleotide excision repair dna gap filling", "Nucleotide excision repair dna incision", "Nucleotide phosphorylation", "Nucleotide salvage", "Nucleotide sugar biosynthetic process", "Nucleotide sugar metabolic process", "Nucleotide sugar transmembrane transport", "Nucleotide transmembrane transport", "Nucleotide transport", "Nucleus localization", "Nucleus organization", "O glycan processing", "Odontoblast differentiation", "Odontogenesis", "Odontogenesis of dentin containing tooth", "Olefinic compound biosynthetic process", "Olefinic compound metabolic process", "Olfactory behavior", "Olfactory bulb interneuron development", "Olfactory bulb interneuron differentiation", "Olfactory lobe development", "Olfactory nerve development", "Oligodendrocyte development", "Oligodendrocyte differentiation", "Oligodendrocyte progenitor proliferation", "Oligopeptide transport", "Oligosaccharide biosynthetic process", "Oligosaccharide catabolic process", "Oligosaccharide lipid intermediate biosynthetic process", "Oligosaccharide metabolic process", "One carbon metabolic process", "Oocyte construction", "Oocyte differentiation", "Oocyte maturation", "Oogenesis", "Opsonization", "Optic nerve development", "Organ growth", "Organ induction", "Organ or tissue specific immune response", "Organelle assembly", "Organelle disassembly", "Organelle fission", "Organelle fusion", "Organelle inheritance", "Organelle localization", "Organelle membrane fusion", "Organelle transport along microtubule", "Organic acid biosynthetic process", "Organic acid catabolic process", "Organic acid metabolic process", "Organic acid transmembrane transport", "Organic acid transport", "Organic anion transport", "Organic cation transport", "Organic cyclic compound catabolic process", "Organic hydroxy compound biosynthetic process", "Organic hydroxy compound catabolic process", "Organic hydroxy compound metabolic process", "Organic hydroxy compound transport", "Organism emergence from protective structure", "Organonitrogen compound biosynthetic process", "Organonitrogen compound catabolic process", "Organophosphate biosynthetic process", "Organophosphate catabolic process", "Organophosphate ester transport", "Organophosphate metabolic process", "Ornithine metabolic process", "Ornithine transport", "Ossification", "Osteoblast differentiation", "Osteoblast proliferation", "Osteoclast development", "Osteoclast differentiation", "Osteoclast fusion", "Otic vesicle development", "Otic vesicle formation", "Otic vesicle morphogenesis", "Otolith development", "Outer dynein arm assembly", "Outer ear morphogenesis", "Outer mitochondrial membrane organization", "Outflow tract morphogenesis", "Outflow tract septum morphogenesis", "Ovarian follicle development", "Oviduct development", "Ovulation", "Ovulation cycle", "Ovulation cycle process", "Ovulation from ovarian follicle", "Oxaloacetate metabolic process", "Oxaloacetate transport", "Oxidative demethylation", "Oxidative dna demethylation", "Oxidative phosphorylation", "Oxidative rna demethylation", "Oxygen homeostasis", "P body assembly", "P38mapk cascade", "Pallium development", "Pancreas development", "Pancreatic a cell differentiation", "Pancreatic juice secretion", "Pantothenate metabolic process", "Parallel actin filament bundle assembly", "Paranodal junction assembly", "Parasympathetic nervous system development", "Parathyroid gland development", "Paraxial mesoderm development", "Paraxial mesoderm formation", "Paraxial mesoderm morphogenesis", "Parkin mediated stimulation of mitophagy in response to mitochondrial depolarization", "Pathway restricted smad protein phosphorylation", "Pattern recognition receptor signaling pathway", "Pattern specification involved in kidney development", "Pattern specification process", "Penetration of zona pellucida", "Penile erection", "Pentose catabolic process", "Pentose metabolic process", "Pentose phosphate shunt", "Pentose phosphate shunt non oxidative branch", "Peptide antigen assembly with mhc protein complex", "Peptide biosynthetic process", "Peptide catabolic process", "Peptide cross linking", "Peptide metabolic process", "Peptide modification", "Peptide transport", "Peptidyl amino acid modification", "Peptidyl arginine methylation", "Peptidyl arginine methylation to asymmetrical dimethyl arginine", "Peptidyl arginine modification", "Peptidyl arginine n methylation", "Peptidyl asparagine modification", "Peptidyl cysteine modification", "Peptidyl diphthamide biosynthetic process from peptidyl histidine", "Peptidyl glutamic acid modification", "Peptidyl glutamine methylation", "Peptidyl histidine modification", "Peptidyl lysine acetylation", "Peptidyl lysine deacetylation", "Peptidyl lysine dimethylation", "Peptidyl lysine hydroxylation", "Peptidyl lysine methylation", "Peptidyl lysine modification", "Peptidyl lysine trimethylation", "Peptidyl methionine modification", "Peptidyl proline hydroxylation", "Peptidyl proline hydroxylation to 4 hydroxy l proline", "Peptidyl proline modification", "Peptidyl serine autophosphorylation", "Peptidyl serine dephosphorylation", "Peptidyl serine modification", "Peptidyl threonine dephosphorylation", "Peptidyl threonine modification", "Peptidyl tyrosine autophosphorylation", "Peptidyl tyrosine dephosphorylation", "Peptidyl tyrosine dephosphorylation involved in inactivation of protein kinase activity", "Peptidyl tyrosine modification", "Pericyte cell differentiation", "Peripheral nervous system axon regeneration", "Peripheral nervous system development", "Peripheral nervous system myelin maintenance", "Perk mediated unfolded protein response", "Peroxisomal transport", "Peroxisome fission", "Peroxisome organization", "Peroxisome proliferator activated receptor signaling pathway", "Ph reduction", "Phagocytosis", "Phagocytosis recognition", "Phagolysosome assembly", "Phagosome acidification", "Phagosome lysosome fusion", "Phagosome maturation", "Pharyngeal system development", "Phenol containing compound biosynthetic process", "Phenol containing compound catabolic process", "Phenol containing compound metabolic process", "Phenotypic switching", "Phosphagen metabolic process", "Phosphate ion transmembrane transport", "Phosphate ion transport", "Phosphatidic acid metabolic process", "Phosphatidylcholine acyl chain remodeling", "Phosphatidylcholine biosynthetic process", "Phosphatidylcholine catabolic process", "Phosphatidylcholine metabolic process", "Phosphatidylethanolamine biosynthetic process", "Phosphatidylethanolamine metabolic process", "Phosphatidylglycerol acyl chain remodeling", "Phosphatidylglycerol biosynthetic process", "Phosphatidylglycerol metabolic process", "Phosphatidylinositol 3 kinase signaling", "Phosphatidylinositol 3 phosphate biosynthetic process", "Phosphatidylinositol acyl chain remodeling", "Phosphatidylinositol biosynthetic process", "Phosphatidylinositol dephosphorylation", "Phosphatidylinositol metabolic process", "Phosphatidylinositol phosphate biosynthetic process", "Phosphatidylserine acyl chain remodeling", "Phosphatidylserine metabolic process", "Phospholipase c activating dopamine receptor signaling pathway", "Phospholipase c activating g protein coupled receptor signaling pathway", "Phospholipid biosynthetic process", "Phospholipid catabolic process", "Phospholipid dephosphorylation", "Phospholipid efflux", "Phospholipid homeostasis", "Phospholipid metabolic process", "Phospholipid transport", "Phosphorylation", "Phosphorylation of rna polymerase ii c terminal domain", "Photoperiodism", "Photoreceptor cell development", "Photoreceptor cell differentiation", "Photoreceptor cell maintenance", "Photoreceptor cell outer segment organization", "Phototransduction", "Phototransduction visible light", "Physiological cardiac muscle hypertrophy", "Piecemeal microautophagy of the nucleus", "Pigment accumulation", "Pigment biosynthetic process", "Pigment cell differentiation", "Pigment granule localization", "Pigment granule maturation", "Pigment granule organization", "Pigment metabolic process", "Pigmentation", "Pinocytosis", "Pirna metabolic process", "Pituitary gland development", "Placenta blood vessel development", "Placenta development", "Planar cell polarity pathway involved in neural tube closure", "Plasma lipoprotein particle clearance", "Plasma membrane fusion", "Plasma membrane organization", "Plasma membrane phospholipid scrambling", "Plasma membrane raft assembly", "Plasma membrane raft organization", "Plasma membrane repair", "Plasma membrane to endosome transport", "Plasma membrane tubulation", "Plasminogen activation", "Platelet activating factor metabolic process", "Platelet activation", "Platelet aggregation", "Platelet degranulation", "Platelet derived growth factor receptor beta signaling pathway", "Platelet derived growth factor receptor signaling pathway", "Platelet morphogenesis", "Plus end directed organelle transport along microtubule", "Pml body organization", "Podosome assembly", "Pointed end actin filament capping", "Polarized epithelial cell differentiation", "Poly a plus mrna export from nucleus", "Poly n acetyllactosamine metabolic process", "Polyadenylation dependent rna catabolic process", "Polyadenylation dependent snorna 3 end processing", "Polyamine biosynthetic process", "Polyamine metabolic process", "Polyketide metabolic process", "Polyol biosynthetic process", "Polyol catabolic process", "Polyol metabolic process", "Polyprenol metabolic process", "Polysaccharide biosynthetic process", "Polysaccharide catabolic process", "Polysaccharide metabolic process", "Pons development", "Pore complex assembly", "Porphyrin containing compound metabolic process", "Positive chemotaxis", "Positive regulation by host of viral genome replication", "Positive regulation by host of viral process", "Positive regulation by host of viral transcription", "Positive regulation by symbiont of entry into host", "Positive regulation of 3 utr mediated mrna stabilization", "Positive regulation of actin cytoskeleton reorganization", "Positive regulation of actin filament bundle assembly", "Positive regulation of actin filament depolymerization", "Positive regulation of actin filament polymerization", "Positive regulation of actin nucleation", "Positive regulation of action potential", "Positive regulation of activated t cell proliferation", "Positive regulation of activin receptor signaling pathway", "Positive regulation of acute inflammatory response", "Positive regulation of acute inflammatory response to antigenic stimulus", "Positive regulation of adaptive immune response", "Positive regulation of adipose tissue development", "Positive regulation of alcohol biosynthetic process", "Positive regulation of alkaline phosphatase activity", "Positive regulation of alpha beta t cell activation", "Positive regulation of alpha beta t cell differentiation", "Positive regulation of alpha beta t cell proliferation", "Positive regulation of amine transport", "Positive regulation of amino acid transport", "Positive regulation of amyloid beta clearance", "Positive regulation of amyloid beta formation", "Positive regulation of amyloid precursor protein biosynthetic process", "Positive regulation of amyloid precursor protein catabolic process", "Positive regulation of animal organ morphogenesis", "Positive regulation of anion transmembrane transport", "Positive regulation of anion transport", "Positive regulation of anoikis", "Positive regulation of antigen receptor mediated signaling pathway", "Positive regulation of apoptotic dna fragmentation", "Positive regulation of apoptotic signaling pathway", "Positive regulation of arp2 3 complex mediated actin nucleation", "Positive regulation of aspartic type peptidase activity", "Positive regulation of astrocyte differentiation", "Positive regulation of atp biosynthetic process", "Positive regulation of atp dependent activity", "Positive regulation of atp metabolic process", "Positive regulation of atpase coupled calcium transmembrane transporter activity", "Positive regulation of attachment of spindle microtubules to kinetochore", "Positive regulation of autophagosome maturation", "Positive regulation of autophagy", "Positive regulation of autophagy of mitochondrion", "Positive regulation of axon extension", "Positive regulation of axon extension involved in axon guidance", "Positive regulation of axonogenesis", "Positive regulation of b cell activation", "Positive regulation of b cell differentiation", "Positive regulation of b cell mediated immunity", "Positive regulation of b cell proliferation", "Positive regulation of b cell receptor signaling pathway", "Positive regulation of basement membrane assembly involved in embryonic body morphogenesis", "Positive regulation of behavior", "Positive regulation of binding", "Positive regulation of biomineralization", "Positive regulation of blood brain barrier permeability", "Positive regulation of blood circulation", "Positive regulation of blood pressure", "Positive regulation of blood pressure by epinephrine norepinephrine", "Positive regulation of blood vessel endothelial cell migration", "Positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis", "Positive regulation of bmp signaling pathway", "Positive regulation of bone mineralization", "Positive regulation of bone resorption", "Positive regulation of brown fat cell differentiation", "Positive regulation of calcineurin mediated signaling", "Positive regulation of calcium ion dependent exocytosis", "Positive regulation of calcium ion import", "Positive regulation of calcium ion transmembrane transport", "Positive regulation of calcium ion transmembrane transporter activity", "Positive regulation of calcium ion transport", "Positive regulation of calcium ion transport into cytosol", "Positive regulation of calcium mediated signaling", "Positive regulation of camp dependent protein kinase activity", "Positive regulation of camp mediated signaling", "Positive regulation of canonical wnt signaling pathway", "Positive regulation of carbohydrate metabolic process", "Positive regulation of cardiac muscle adaptation", "Positive regulation of cardiac muscle cell differentiation", "Positive regulation of cardiac muscle cell proliferation", "Positive regulation of cardioblast differentiation", "Positive regulation of cardiocyte differentiation", "Positive regulation of cartilage development", "Positive regulation of catabolic process", "Positive regulation of catalytic activity", "Positive regulation of catecholamine metabolic process", "Positive regulation of cation channel activity", "Positive regulation of cd4 positive alpha beta t cell activation", "Positive regulation of cd4 positive alpha beta t cell differentiation", "Positive regulation of cd8 positive alpha beta t cell activation", "Positive regulation of cell activation", "Positive regulation of cell adhesion", "Positive regulation of cell adhesion molecule production", "Positive regulation of cell aging", "Positive regulation of cell cell adhesion", "Positive regulation of cell cell adhesion mediated by cadherin", "Positive regulation of cell cycle", "Positive regulation of cell cycle checkpoint", "Positive regulation of cell cycle g1 s phase transition", "Positive regulation of cell cycle g2 m phase transition", "Positive regulation of cell cycle phase transition", "Positive regulation of cell cycle process", "Positive regulation of cell death", "Positive regulation of cell development", "Positive regulation of cell differentiation", "Positive regulation of cell division", "Positive regulation of cell growth", "Positive regulation of cell growth involved in cardiac muscle cell development", "Positive regulation of cell junction assembly", "Positive regulation of cell killing", "Positive regulation of cell matrix adhesion", "Positive regulation of cell maturation", "Positive regulation of cell migration by vascular endothelial growth factor signaling pathway", "Positive regulation of cell migration involved in sprouting angiogenesis", "Positive regulation of cell morphogenesis involved in differentiation", "Positive regulation of cell population proliferation", "Positive regulation of cell projection organization", "Positive regulation of cell size", "Positive regulation of cell substrate adhesion", "Positive regulation of cell substrate junction organization", "Positive regulation of cellular amide metabolic process", "Positive regulation of cellular amine metabolic process", "Positive regulation of cellular biosynthetic process", "Positive regulation of cellular carbohydrate metabolic process", "Positive regulation of cellular component biogenesis", "Positive regulation of cellular component organization", "Positive regulation of cellular extravasation", "Positive regulation of cellular protein catabolic process", "Positive regulation of cellular respiration", "Positive regulation of cellular response to insulin stimulus", "Positive regulation of cellular response to transforming growth factor beta stimulus", "Positive regulation of centriole elongation", "Positive regulation of centriole replication", "Positive regulation of chemokine c c motif ligand 5 production", "Positive regulation of chemokine c x c motif ligand 2 production", "Positive regulation of chemokine production", "Positive regulation of chemotaxis", "Positive regulation of cholesterol biosynthetic process", "Positive regulation of cholesterol efflux", "Positive regulation of cholesterol esterification", "Positive regulation of cholesterol metabolic process", "Positive regulation of cholesterol storage", "Positive regulation of chondrocyte differentiation", "Positive regulation of chromatin binding", "Positive regulation of chromatin organization", "Positive regulation of chromosome condensation", "Positive regulation of chromosome organization", "Positive regulation of chromosome segregation", "Positive regulation of chromosome separation", "Positive regulation of cilium assembly", "Positive regulation of circadian rhythm", "Positive regulation of clathrin dependent endocytosis", "Positive regulation of coagulation", "Positive regulation of cold induced thermogenesis", "Positive regulation of collagen metabolic process", "Positive regulation of collateral sprouting", "Positive regulation of complement activation", "Positive regulation of connective tissue replacement", "Positive regulation of corticosteroid hormone secretion", "Positive regulation of cyclase activity", "Positive regulation of cyclic nucleotide phosphodiesterase activity", "Positive regulation of cyclin dependent protein kinase activity", "Positive regulation of cysteine type endopeptidase activity", "Positive regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Positive regulation of cytokine production", "Positive regulation of cytokine production involved in immune response", "Positive regulation of cytokine production involved in inflammatory response", "Positive regulation of cytokinesis", "Positive regulation of cytoplasmic translation", "Positive regulation of cytoplasmic transport", "Positive regulation of cytoskeleton organization", "Positive regulation of deacetylase activity", "Positive regulation of defense response", "Positive regulation of defense response to virus by host", "Positive regulation of dendrite development", "Positive regulation of dendrite morphogenesis", "Positive regulation of dendritic cell cytokine production", "Positive regulation of dendritic cell differentiation", "Positive regulation of dendritic spine development", "Positive regulation of dendritic spine morphogenesis", "Positive regulation of deoxyribonuclease activity", "Positive regulation of dephosphorylation", "Positive regulation of developmental growth", "Positive regulation of developmental process", "Positive regulation of dna binding", "Positive regulation of dna binding transcription factor activity", "Positive regulation of dna biosynthetic process", "Positive regulation of dna catabolic process", "Positive regulation of dna damage response signal transduction by p53 class mediator", "Positive regulation of dna demethylation", "Positive regulation of dna dependent dna replication", "Positive regulation of dna ligation", "Positive regulation of dna metabolic process", "Positive regulation of dna methylation dependent heterochromatin assembly", "Positive regulation of dna recombination", "Positive regulation of dna repair", "Positive regulation of dna replication", "Positive regulation of dna templated transcription elongation", "Positive regulation of dna templated transcription initiation", "Positive regulation of dopamine receptor signaling pathway", "Positive regulation of double strand break repair", "Positive regulation of double strand break repair via homologous recombination", "Positive regulation of double strand break repair via nonhomologous end joining", "Positive regulation of early endosome to late endosome transport", "Positive regulation of embryonic development", "Positive regulation of enamel mineralization", "Positive regulation of endocytic recycling", "Positive regulation of endocytosis", "Positive regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Positive regulation of endoplasmic reticulum unfolded protein response", "Positive regulation of endothelial cell apoptotic process", "Positive regulation of endothelial cell chemotaxis", "Positive regulation of endothelial cell development", "Positive regulation of endothelial cell differentiation", "Positive regulation of endothelial cell matrix adhesion via fibronectin", "Positive regulation of endothelial cell migration", "Positive regulation of endothelial cell proliferation", "Positive regulation of epidermal cell differentiation", "Positive regulation of epidermal growth factor activated receptor activity", "Positive regulation of epidermis development", "Positive regulation of epithelial cell apoptotic process", "Positive regulation of epithelial cell differentiation", "Positive regulation of epithelial cell migration", "Positive regulation of epithelial cell proliferation", "Positive regulation of epithelial cell proliferation involved in lung morphogenesis", "Positive regulation of epithelial cell proliferation involved in wound healing", "Positive regulation of epithelial to mesenchymal transition", "Positive regulation of er associated ubiquitin dependent protein catabolic process", "Positive regulation of erad pathway", "Positive regulation of erbb signaling pathway", "Positive regulation of erk1 and erk2 cascade", "Positive regulation of erythrocyte differentiation", "Positive regulation of establishment of protein localization", "Positive regulation of establishment of protein localization to mitochondrion", "Positive regulation of establishment of protein localization to telomere", "Positive regulation of excitatory postsynaptic potential", "Positive regulation of execution phase of apoptosis", "Positive regulation of exocytosis", "Positive regulation of exosomal secretion", "Positive regulation of extracellular matrix assembly", "Positive regulation of extracellular matrix disassembly", "Positive regulation of extracellular matrix organization", "Positive regulation of extrinsic apoptotic signaling pathway", "Positive regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Positive regulation of fat cell differentiation", "Positive regulation of fatty acid beta oxidation", "Positive regulation of fatty acid biosynthetic process", "Positive regulation of fatty acid metabolic process", "Positive regulation of fatty acid oxidation", "Positive regulation of fatty acid transport", "Positive regulation of fc receptor mediated stimulatory signaling pathway", "Positive regulation of feeding behavior", "Positive regulation of fibroblast growth factor receptor signaling pathway", "Positive regulation of fibroblast migration", "Positive regulation of fibroblast proliferation", "Positive regulation of filopodium assembly", "Positive regulation of focal adhesion assembly", "Positive regulation of g protein coupled receptor signaling pathway", "Positive regulation of g0 to g1 transition", "Positive regulation of g1 s transition of mitotic cell cycle", "Positive regulation of gastrulation", "Positive regulation of gene expression", "Positive regulation of glial cell differentiation", "Positive regulation of glial cell migration", "Positive regulation of glial cell proliferation", "Positive regulation of gliogenesis", "Positive regulation of glucokinase activity", "Positive regulation of gluconeogenesis", "Positive regulation of glucose import", "Positive regulation of glucose metabolic process", "Positive regulation of glucose transmembrane transport", "Positive regulation of glutamate secretion", "Positive regulation of glycogen metabolic process", "Positive regulation of glycogen starch synthase activity", "Positive regulation of glycolytic process", "Positive regulation of glycoprotein metabolic process", "Positive regulation of golgi to plasma membrane protein transport", "Positive regulation of gonad development", "Positive regulation of granulocyte chemotaxis", "Positive regulation of granulocyte differentiation", "Positive regulation of growth", "Positive regulation of gtpase activity", "Positive regulation of hair follicle development", "Positive regulation of hair follicle maturation", "Positive regulation of heart growth", "Positive regulation of heart rate", "Positive regulation of heat generation", "Positive regulation of helicase activity", "Positive regulation of hematopoietic progenitor cell differentiation", "Positive regulation of hematopoietic stem cell proliferation", "Positive regulation of hemopoiesis", "Positive regulation of hepatocyte proliferation", "Positive regulation of heterotypic cell cell adhesion", "Positive regulation of hexokinase activity", "Positive regulation of hippo signaling", "Positive regulation of histone acetylation", "Positive regulation of histone deacetylation", "Positive regulation of histone h3 k27 methylation", "Positive regulation of histone h3 k4 methylation", "Positive regulation of histone h3 k9 acetylation", "Positive regulation of histone h3 k9 methylation", "Positive regulation of histone h4 acetylation", "Positive regulation of histone methylation", "Positive regulation of histone modification", "Positive regulation of histone phosphorylation", "Positive regulation of histone ubiquitination", "Positive regulation of homotypic cell cell adhesion", "Positive regulation of hormone biosynthetic process", "Positive regulation of hormone metabolic process", "Positive regulation of hormone secretion", "Positive regulation of humoral immune response", "Positive regulation of hydrogen peroxide mediated programmed cell death", "Positive regulation of hydrogen peroxide metabolic process", "Positive regulation of hydrolase activity", "Positive regulation of i kappab kinase nf kappab signaling", "Positive regulation of i kappab phosphorylation", "Positive regulation of immune effector process", "Positive regulation of immune response", "Positive regulation of immune system process", "Positive regulation of immunoglobulin production", "Positive regulation of inclusion body assembly", "Positive regulation of inflammatory response", "Positive regulation of inflammatory response to antigenic stimulus", "Positive regulation of inhibitory postsynaptic potential", "Positive regulation of innate immune response", "Positive regulation of insulin like growth factor receptor signaling pathway", "Positive regulation of insulin secretion", "Positive regulation of insulin secretion involved in cellular response to glucose stimulus", "Positive regulation of integrin activation", "Positive regulation of integrin mediated signaling pathway", "Positive regulation of interferon alpha production", "Positive regulation of interferon beta production", "Positive regulation of interferon gamma production", "Positive regulation of interleukin 1 alpha production", "Positive regulation of interleukin 1 beta production", "Positive regulation of interleukin 1 production", "Positive regulation of interleukin 10 production", "Positive regulation of interleukin 12 production", "Positive regulation of interleukin 13 production", "Positive regulation of interleukin 17 production", "Positive regulation of interleukin 18 production", "Positive regulation of interleukin 2 production", "Positive regulation of interleukin 4 production", "Positive regulation of interleukin 6 production", "Positive regulation of interleukin 8 production", "Positive regulation of intracellular lipid transport", "Positive regulation of intracellular protein transport", "Positive regulation of intracellular signal transduction", "Positive regulation of intracellular steroid hormone receptor signaling pathway", "Positive regulation of intracellular transport", "Positive regulation of intrinsic apoptotic signaling pathway", "Positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Positive regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Positive regulation of ion transmembrane transport", "Positive regulation of ion transport", "Positive regulation of ire1 mediated unfolded protein response", "Positive regulation of isotype switching", "Positive regulation of isotype switching to iga isotypes", "Positive regulation of isotype switching to igg isotypes", "Positive regulation of jnk cascade", "Positive regulation of jun kinase activity", "Positive regulation of keratinocyte differentiation", "Positive regulation of keratinocyte proliferation", "Positive regulation of kinase activity", "Positive regulation of lamellipodium assembly", "Positive regulation of lamellipodium morphogenesis", "Positive regulation of lamellipodium organization", "Positive regulation of leukocyte apoptotic process", "Positive regulation of leukocyte cell cell adhesion", "Positive regulation of leukocyte chemotaxis", "Positive regulation of leukocyte degranulation", "Positive regulation of leukocyte mediated immunity", "Positive regulation of leukocyte migration", "Positive regulation of leukocyte proliferation", "Positive regulation of ligase activity", "Positive regulation of lipase activity", "Positive regulation of lipid biosynthetic process", "Positive regulation of lipid catabolic process", "Positive regulation of lipid kinase activity", "Positive regulation of lipid localization", "Positive regulation of lipid metabolic process", "Positive regulation of lipid storage", "Positive regulation of lipid transport", "Positive regulation of lipopolysaccharide mediated signaling pathway", "Positive regulation of lipoprotein particle clearance", "Positive regulation of locomotion", "Positive regulation of long term neuronal synaptic plasticity", "Positive regulation of long term synaptic potentiation", "Positive regulation of low density lipoprotein receptor activity", "Positive regulation of lyase activity", "Positive regulation of lymphocyte anergy", "Positive regulation of lymphocyte apoptotic process", "Positive regulation of lymphocyte chemotaxis", "Positive regulation of lymphocyte differentiation", "Positive regulation of lymphocyte mediated immunity", "Positive regulation of lymphocyte migration", "Positive regulation of macroautophagy", "Positive regulation of macrophage activation", "Positive regulation of macrophage chemotaxis", "Positive regulation of macrophage cytokine production", "Positive regulation of macrophage differentiation", "Positive regulation of macrophage migration", "Positive regulation of maintenance of sister chromatid cohesion", "Positive regulation of mammary gland epithelial cell proliferation", "Positive regulation of map kinase activity", "Positive regulation of mapk cascade", "Positive regulation of mast cell activation", "Positive regulation of mast cell activation involved in immune response", "Positive regulation of megakaryocyte differentiation", "Positive regulation of membrane depolarization", "Positive regulation of membrane permeability", "Positive regulation of membrane potential", "Positive regulation of membrane protein ectodomain proteolysis", "Positive regulation of mesenchymal cell proliferation", "Positive regulation of mesenchymal stem cell proliferation", "Positive regulation of metalloendopeptidase activity", "Positive regulation of metallopeptidase activity", "Positive regulation of metaphase anaphase transition of cell cycle", "Positive regulation of mhc class i biosynthetic process", "Positive regulation of mhc class ii biosynthetic process", "Positive regulation of microglial cell activation", "Positive regulation of microtubule binding", "Positive regulation of microtubule nucleation", "Positive regulation of microtubule polymerization or depolymerization", "Positive regulation of mirna catabolic process", "Positive regulation of mirna mediated gene silencing by inhibition of translation", "Positive regulation of mirna metabolic process", "Positive regulation of mirna transcription", "Positive regulation of mitochondrial calcium ion concentration", "Positive regulation of mitochondrial depolarization", "Positive regulation of mitochondrial fission", "Positive regulation of mitochondrial membrane potential", "Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Positive regulation of mitochondrial translation", "Positive regulation of mitochondrion organization", "Positive regulation of mitophagy", "Positive regulation of mitophagy in response to mitochondrial depolarization", "Positive regulation of mitotic cell cycle", "Positive regulation of mitotic cell cycle phase transition", "Positive regulation of mitotic cell cycle spindle assembly checkpoint", "Positive regulation of mitotic nuclear division", "Positive regulation of molecular function", "Positive regulation of monocyte chemotaxis", "Positive regulation of monocyte differentiation", "Positive regulation of mononuclear cell migration", "Positive regulation of monooxygenase activity", "Positive regulation of morphogenesis of an epithelium", "Positive regulation of mrna 3 end processing", "Positive regulation of mrna metabolic process", "Positive regulation of mrna processing", "Positive regulation of mrna splicing via spliceosome", "Positive regulation of mucus secretion", "Positive regulation of multicellular organism growth", "Positive regulation of multicellular organismal process", "Positive regulation of muscle adaptation", "Positive regulation of muscle cell apoptotic process", "Positive regulation of muscle cell differentiation", "Positive regulation of muscle contraction", "Positive regulation of muscle hypertrophy", "Positive regulation of muscle tissue development", "Positive regulation of myelination", "Positive regulation of myeloid cell apoptotic process", "Positive regulation of myeloid cell differentiation", "Positive regulation of myeloid leukocyte cytokine production involved in immune response", "Positive regulation of myeloid leukocyte differentiation", "Positive regulation of myeloid leukocyte mediated immunity", "Positive regulation of myoblast differentiation", "Positive regulation of myoblast fusion", "Positive regulation of myoblast proliferation", "Positive regulation of myotube differentiation", "Positive regulation of nad p h oxidase activity", "Positive regulation of natural killer cell activation", "Positive regulation of natural killer cell mediated cytotoxicity", "Positive regulation of natural killer cell mediated immunity", "Positive regulation of necrotic cell death", "Positive regulation of nervous system development", "Positive regulation of nervous system process", "Positive regulation of neural precursor cell proliferation", "Positive regulation of neuroblast proliferation", "Positive regulation of neurogenesis", "Positive regulation of neuroinflammatory response", "Positive regulation of neuron apoptotic process", "Positive regulation of neuron death", "Positive regulation of neuron differentiation", "Positive regulation of neuron migration", "Positive regulation of neuron projection arborization", "Positive regulation of neuron projection development", "Positive regulation of neuron projection regeneration", "Positive regulation of neurotransmitter secretion", "Positive regulation of neurotransmitter transport", "Positive regulation of neurotransmitter uptake", "Positive regulation of neurotrophin trk receptor signaling pathway", "Positive regulation of neutrophil migration", "Positive regulation of nf kappab transcription factor activity", "Positive regulation of nik nf kappab signaling", "Positive regulation of nitric oxide metabolic process", "Positive regulation of nitric oxide synthase activity", "Positive regulation of nitric oxide synthase biosynthetic process", "Positive regulation of nk t cell activation", "Positive regulation of nlrp3 inflammasome complex assembly", "Positive regulation of non motile cilium assembly", "Positive regulation of notch signaling pathway", "Positive regulation of nuclear cell cycle dna replication", "Positive regulation of nuclear division", "Positive regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Positive regulation of nuclease activity", "Positive regulation of nucleobase containing compound metabolic process", "Positive regulation of nucleobase containing compound transport", "Positive regulation of nucleocytoplasmic transport", "Positive regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Positive regulation of nucleotide binding oligomerization domain containing signaling pathway", "Positive regulation of nucleotide biosynthetic process", "Positive regulation of nucleotide metabolic process", "Positive regulation of oligodendrocyte differentiation", "Positive regulation of opsonization", "Positive regulation of organ growth", "Positive regulation of organelle assembly", "Positive regulation of organelle organization", "Positive regulation of organic acid transport", "Positive regulation of ossification", "Positive regulation of osteoblast differentiation", "Positive regulation of osteoblast proliferation", "Positive regulation of osteoclast differentiation", "Positive regulation of oxidative stress induced cell death", "Positive regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Positive regulation of oxidative stress induced neuron death", "Positive regulation of oxidoreductase activity", "Positive regulation of p38mapk cascade", "Positive regulation of pathway restricted smad protein phosphorylation", "Positive regulation of pattern recognition receptor signaling pathway", "Positive regulation of peptidase activity", "Positive regulation of peptide secretion", "Positive regulation of peptidyl lysine acetylation", "Positive regulation of peptidyl serine phosphorylation", "Positive regulation of peptidyl threonine phosphorylation", "Positive regulation of peptidyl tyrosine phosphorylation", "Positive regulation of phagocytosis", "Positive regulation of phosphatase activity", "Positive regulation of phosphatidylinositol 3 kinase signaling", "Positive regulation of phospholipase a2 activity", "Positive regulation of phospholipase activity", "Positive regulation of phospholipid biosynthetic process", "Positive regulation of phospholipid metabolic process", "Positive regulation of phospholipid translocation", "Positive regulation of phosphoprotein phosphatase activity", "Positive regulation of phosphorus metabolic process", "Positive regulation of pinocytosis", "Positive regulation of plasma membrane bounded cell projection assembly", "Positive regulation of plasminogen activation", "Positive regulation of platelet aggregation", "Positive regulation of platelet derived growth factor receptor signaling pathway", "Positive regulation of podosome assembly", "Positive regulation of posttranscriptional gene silencing", "Positive regulation of potassium ion import across plasma membrane", "Positive regulation of potassium ion transmembrane transporter activity", "Positive regulation of potassium ion transport", "Positive regulation of production of mirnas involved in gene silencing by mirna", "Positive regulation of production of molecular mediator of immune response", "Positive regulation of programmed necrotic cell death", "Positive regulation of prostaglandin biosynthetic process", "Positive regulation of proteasomal ubiquitin dependent protein catabolic process", "Positive regulation of protein acetylation", "Positive regulation of protein autophosphorylation", "Positive regulation of protein binding", "Positive regulation of protein catabolic process", "Positive regulation of protein catabolic process in the vacuole", "Positive regulation of protein containing complex assembly", "Positive regulation of protein containing complex disassembly", "Positive regulation of protein deacetylation", "Positive regulation of protein dephosphorylation", "Positive regulation of protein depolymerization", "Positive regulation of protein deubiquitination", "Positive regulation of protein exit from endoplasmic reticulum", "Positive regulation of protein export from nucleus", "Positive regulation of protein glycosylation", "Positive regulation of protein import", "Positive regulation of protein k63 linked ubiquitination", "Positive regulation of protein kinase a signaling", "Positive regulation of protein kinase activity", "Positive regulation of protein kinase b signaling", "Positive regulation of protein kinase c signaling", "Positive regulation of protein localization", "Positive regulation of protein localization to cell cortex", "Positive regulation of protein localization to cell periphery", "Positive regulation of protein localization to cell surface", "Positive regulation of protein localization to centrosome", "Positive regulation of protein localization to cilium", "Positive regulation of protein localization to early endosome", "Positive regulation of protein localization to membrane", "Positive regulation of protein localization to nucleus", "Positive regulation of protein localization to synapse", "Positive regulation of protein maturation", "Positive regulation of protein metabolic process", "Positive regulation of protein modification by small protein conjugation or removal", "Positive regulation of protein modification process", "Positive regulation of protein monoubiquitination", "Positive regulation of protein neddylation", "Positive regulation of protein phosphorylation", "Positive regulation of protein polymerization", "Positive regulation of protein polyubiquitination", "Positive regulation of protein secretion", "Positive regulation of protein serine threonine kinase activity", "Positive regulation of protein sumoylation", "Positive regulation of protein targeting to membrane", "Positive regulation of protein tyrosine kinase activity", "Positive regulation of proteolysis", "Positive regulation of proteolysis involved in cellular protein catabolic process", "Positive regulation of pseudopodium assembly", "Positive regulation of reactive oxygen species biosynthetic process", "Positive regulation of reactive oxygen species metabolic process", "Positive regulation of receptor binding", "Positive regulation of receptor catabolic process", "Positive regulation of receptor clustering", "Positive regulation of receptor internalization", "Positive regulation of receptor mediated endocytosis", "Positive regulation of receptor recycling", "Positive regulation of receptor signaling pathway via stat", "Positive regulation of regulated secretory pathway", "Positive regulation of release of cytochrome c from mitochondria", "Positive regulation of release of sequestered calcium ion into cytosol", "Positive regulation of renal sodium excretion", "Positive regulation of reproductive process", "Positive regulation of respiratory burst", "Positive regulation of response to biotic stimulus", "Positive regulation of response to cytokine stimulus", "Positive regulation of response to dna damage stimulus", "Positive regulation of response to endoplasmic reticulum stress", "Positive regulation of response to external stimulus", "Positive regulation of response to interferon gamma", "Positive regulation of response to oxidative stress", "Positive regulation of response to reactive oxygen species", "Positive regulation of response to tumor cell", "Positive regulation of response to wounding", "Positive regulation of retinoic acid receptor signaling pathway", "Positive regulation of rho protein signal transduction", "Positive regulation of rig i signaling pathway", "Positive regulation of rna binding", "Positive regulation of rna export from nucleus", "Positive regulation of rna metabolic process", "Positive regulation of rna polymerase ii transcription preinitiation complex assembly", "Positive regulation of rna splicing", "Positive regulation of rrna processing", "Positive regulation of ruffle assembly", "Positive regulation of ryanodine sensitive calcium release channel activity", "Positive regulation of secondary metabolite biosynthetic process", "Positive regulation of secretion", "Positive regulation of sequestering of calcium ion", "Positive regulation of sequestering of triglyceride", "Positive regulation of signal transduction by p53 class mediator", "Positive regulation of signaling", "Positive regulation of signaling receptor activity", "Positive regulation of sister chromatid cohesion", "Positive regulation of skeletal muscle fiber development", "Positive regulation of skeletal muscle tissue development", "Positive regulation of smad protein signal transduction", "Positive regulation of small gtpase mediated signal transduction", "Positive regulation of small molecule metabolic process", "Positive regulation of smooth muscle cell apoptotic process", "Positive regulation of smooth muscle cell differentiation", "Positive regulation of smooth muscle cell migration", "Positive regulation of smooth muscle cell proliferation", "Positive regulation of smooth muscle contraction", "Positive regulation of smoothened signaling pathway", "Positive regulation of sodium ion transmembrane transport", "Positive regulation of sodium ion transmembrane transporter activity", "Positive regulation of sodium ion transport", "Positive regulation of sphingolipid biosynthetic process", "Positive regulation of spindle assembly", "Positive regulation of sprouting angiogenesis", "Positive regulation of stem cell differentiation", "Positive regulation of stem cell proliferation", "Positive regulation of steroid biosynthetic process", "Positive regulation of steroid hormone biosynthetic process", "Positive regulation of steroid hormone secretion", "Positive regulation of steroid metabolic process", "Positive regulation of sterol transport", "Positive regulation of stress activated protein kinase signaling cascade", "Positive regulation of stress fiber assembly", "Positive regulation of striated muscle cell apoptotic process", "Positive regulation of striated muscle cell differentiation", "Positive regulation of striated muscle contraction", "Positive regulation of substrate adhesion dependent cell spreading", "Positive regulation of supramolecular fiber organization", "Positive regulation of synapse assembly", "Positive regulation of synapse maturation", "Positive regulation of synaptic plasticity", "Positive regulation of synaptic transmission", "Positive regulation of synaptic transmission gabaergic", "Positive regulation of synaptic transmission glutamatergic", "Positive regulation of synaptic vesicle endocytosis", "Positive regulation of synaptic vesicle exocytosis", "Positive regulation of synaptic vesicle recycling", "Positive regulation of syncytium formation by plasma membrane fusion", "Positive regulation of systemic arterial blood pressure", "Positive regulation of t cell apoptotic process", "Positive regulation of t cell cytokine production", "Positive regulation of t cell differentiation in thymus", "Positive regulation of t cell mediated cytotoxicity", "Positive regulation of t cell mediated immune response to tumor cell", "Positive regulation of t cell mediated immunity", "Positive regulation of t cell migration", "Positive regulation of t cell proliferation", "Positive regulation of t cell receptor signaling pathway", "Positive regulation of t cell tolerance induction", "Positive regulation of t helper 1 cell differentiation", "Positive regulation of t helper cell differentiation", "Positive regulation of tau protein kinase activity", "Positive regulation of telomerase activity", "Positive regulation of telomerase rna localization to cajal body", "Positive regulation of telomere capping", "Positive regulation of telomere maintenance", "Positive regulation of telomere maintenance via telomere lengthening", "Positive regulation of tissue remodeling", "Positive regulation of tolerance induction", "Positive regulation of toll like receptor 2 signaling pathway", "Positive regulation of toll like receptor 3 signaling pathway", "Positive regulation of toll like receptor 9 signaling pathway", "Positive regulation of toll like receptor signaling pathway", "Positive regulation of tooth mineralization", "Positive regulation of tor signaling", "Positive regulation of torc1 signaling", "Positive regulation of transcription by rna polymerase i", "Positive regulation of transcription by rna polymerase ii", "Positive regulation of transcription by rna polymerase iii", "Positive regulation of transcription elongation from rna polymerase ii promoter", "Positive regulation of transcription from rna polymerase ii promoter in response to endoplasmic reticulum stress", "Positive regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Positive regulation of transcription from rna polymerase ii promoter in response to stress", "Positive regulation of transcription from rna polymerase ii promoter involved in cellular response to chemical stimulus", "Positive regulation of transcription of notch receptor target", "Positive regulation of transcription of nucleolar large rrna by rna polymerase i", "Positive regulation of transcription regulatory region dna binding", "Positive regulation of transferase activity", "Positive regulation of transforming growth factor beta production", "Positive regulation of transforming growth factor beta1 production", "Positive regulation of translation", "Positive regulation of translation in response to endoplasmic reticulum stress", "Positive regulation of translation in response to stress", "Positive regulation of translational initiation", "Positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Positive regulation of transmembrane transport", "Positive regulation of transmission of nerve impulse", "Positive regulation of transport", "Positive regulation of transporter activity", "Positive regulation of triglyceride biosynthetic process", "Positive regulation of triglyceride catabolic process", "Positive regulation of triglyceride metabolic process", "Positive regulation of trophoblast cell migration", "Positive regulation of tumor necrosis factor mediated signaling pathway", "Positive regulation of tumor necrosis factor superfamily cytokine production", "Positive regulation of type i interferon mediated signaling pathway", "Positive regulation of type i interferon production", "Positive regulation of tyrosine phosphorylation of stat protein", "Positive regulation of ubiquitin dependent protein catabolic process", "Positive regulation of ubiquitin protein ligase activity", "Positive regulation of ubiquitin protein transferase activity", "Positive regulation of unsaturated fatty acid biosynthetic process", "Positive regulation of urine volume", "Positive regulation of uterine smooth muscle contraction", "Positive regulation of vacuole organization", "Positive regulation of vascular associated smooth muscle cell apoptotic process", "Positive regulation of vascular associated smooth muscle cell differentiation", "Positive regulation of vascular associated smooth muscle cell migration", "Positive regulation of vascular associated smooth muscle cell proliferation", "Positive regulation of vascular endothelial cell proliferation", "Positive regulation of vascular endothelial growth factor production", "Positive regulation of vascular endothelial growth factor signaling pathway", "Positive regulation of vascular permeability", "Positive regulation of vasculature development", "Positive regulation of vasculogenesis", "Positive regulation of vesicle fusion", "Positive regulation of viral genome replication", "Positive regulation of viral life cycle", "Positive regulation of viral process", "Positive regulation of vitamin d receptor signaling pathway", "Positive regulation of voltage gated calcium channel activity", "Positive regulation of wnt signaling pathway", "Positive regulation of wound healing", "Positive regulation of wound healing spreading of epidermal cells", "Positive t cell selection", "Post anal tail morphogenesis", "Post chaperonin tubulin folding pathway", "Post embryonic animal morphogenesis", "Post embryonic animal organ development", "Post embryonic animal organ morphogenesis", "Post embryonic camera type eye development", "Post embryonic development", "Post embryonic eye morphogenesis", "Post golgi vesicle mediated transport", "Post translational protein modification", "Postreplication repair", "Postsynapse assembly", "Postsynapse organization", "Postsynapse to nucleus signaling pathway", "Postsynaptic actin cytoskeleton organization", "Postsynaptic cytoskeleton organization", "Postsynaptic density protein 95 clustering", "Postsynaptic membrane assembly", "Postsynaptic membrane organization", "Postsynaptic modulation of chemical synaptic transmission", "Postsynaptic neurotransmitter receptor internalization", "Postsynaptic signal transduction", "Postsynaptic specialization organization", "Posttranscriptional regulation of gene expression", "Posttranslational protein targeting to endoplasmic reticulum membrane", "Posttranslational protein targeting to membrane translocation", "Potassium ion export across plasma membrane", "Potassium ion homeostasis", "Potassium ion import across plasma membrane", "Potassium ion transport", "Pre mirna processing", "Preassembly of gpi anchor in er membrane", "Prenylation", "Prepulse inhibition", "Presynapse organization", "Presynaptic active zone organization", "Presynaptic endocytosis", "Presynaptic modulation of chemical synaptic transmission", "Prevention of polyspermy", "Primary alcohol biosynthetic process", "Primary alcohol catabolic process", "Primary alcohol metabolic process", "Primary amino compound biosynthetic process", "Primary amino compound metabolic process", "Primary mirna processing", "Primitive hemopoiesis", "Pro b cell differentiation", "Process utilizing autophagic mechanism", "Production of molecular mediator involved in inflammatory response", "Production of molecular mediator of immune response", "Production of sirna involved in rna interference", "Progesterone biosynthetic process", "Progesterone metabolic process", "Progesterone receptor signaling pathway", "Programmed cell death", "Programmed cell death in response to reactive oxygen species", "Programmed cell death involved in cell development", "Programmed necrotic cell death", "Prolactin secretion", "Proline metabolic process", "Pronephros development", "Proprioception", "Prostaglandin transport", "Prostanoid biosynthetic process", "Prostanoid metabolic process", "Prostate gland development", "Prostate gland growth", "Prosthetic group metabolic process", "Proteasomal protein catabolic process", "Proteasome assembly", "Proteasome mediated ubiquitin dependent protein catabolic process", "Protection from natural killer cell mediated cytotoxicity", "Protection from non homologous end joining at telomere", "Protein acetylation", "Protein activation cascade", "Protein acylation", "Protein adp ribosylation", "Protein auto adp ribosylation", "Protein autophosphorylation", "Protein autoprocessing", "Protein autoubiquitination", "Protein catabolic process", "Protein catabolic process in the vacuole", "Protein complex oligomerization", "Protein containing complex disassembly", "Protein containing complex localization", "Protein containing complex organization", "Protein containing complex remodeling", "Protein deglycosylation", "Protein demannosylation", "Protein demethylation", "Protein deneddylation", "Protein depalmitoylation", "Protein dephosphorylation", "Protein depolymerization", "Protein destabilization", "Protein desumoylation", "Protein deubiquitination involved in ubiquitin dependent protein catabolic process", "Protein dna complex assembly", "Protein dna complex disassembly", "Protein dna complex subunit organization", "Protein dna covalent cross linking repair", "Protein exit from endoplasmic reticulum", "Protein export from nucleus", "Protein folding", "Protein folding in endoplasmic reticulum", "Protein geranylgeranylation", "Protein heterooligomerization", "Protein heterotetramerization", "Protein hexamerization", "Protein homooligomerization", "Protein homotetramerization", "Protein hydroxylation", "Protein import", "Protein import into mitochondrial matrix", "Protein import into peroxisome matrix", "Protein import into peroxisome membrane", "Protein insertion into er membrane", "Protein insertion into er membrane by stop transfer membrane anchor sequence", "Protein insertion into membrane", "Protein insertion into mitochondrial inner membrane", "Protein insertion into mitochondrial membrane involved in apoptotic signaling pathway", "Protein k11 linked ubiquitination", "Protein k27 linked ubiquitination", "Protein k29 linked ubiquitination", "Protein k48 linked deubiquitination", "Protein k48 linked ubiquitination", "Protein k6 linked ubiquitination", "Protein k63 linked deubiquitination", "Protein k63 linked ubiquitination", "Protein kinase a signaling", "Protein kinase b signaling", "Protein kinase c signaling", "Protein lipid complex assembly", "Protein lipid complex subunit organization", "Protein localization to adherens junction", "Protein localization to axon", "Protein localization to basolateral plasma membrane", "Protein localization to cell cell junction", "Protein localization to cell cortex", "Protein localization to cell junction", "Protein localization to cell periphery", "Protein localization to cell surface", "Protein localization to chromatin", "Protein localization to chromosome", "Protein localization to chromosome centromeric region", "Protein localization to chromosome telomeric region", "Protein localization to ciliary membrane", "Protein localization to cilium", "Protein localization to condensed chromosome", "Protein localization to cytoplasmic stress granule", "Protein localization to cytoskeleton", "Protein localization to early endosome", "Protein localization to endoplasmic reticulum", "Protein localization to endoplasmic reticulum exit site", "Protein localization to endosome", "Protein localization to extracellular region", "Protein localization to golgi apparatus", "Protein localization to lysosome", "Protein localization to membrane raft", "Protein localization to microtubule", "Protein localization to microtubule end", "Protein localization to microtubule organizing center", "Protein localization to mitochondrion", "Protein localization to non motile cilium", "Protein localization to nuclear body", "Protein localization to nuclear envelope", "Protein localization to nucleolus", "Protein localization to nucleoplasm", "Protein localization to nucleus", "Protein localization to organelle", "Protein localization to perinuclear region of cytoplasm", "Protein localization to phagophore assembly site", "Protein localization to photoreceptor outer segment", "Protein localization to plasma membrane", "Protein localization to postsynapse", "Protein localization to presynapse", "Protein localization to synapse", "Protein localization to vacuole", "Protein mannosylation", "Protein maturation", "Protein maturation by 4fe 4s cluster transfer", "Protein maturation by iron sulfur cluster transfer", "Protein maturation by protein folding", "Protein methylation", "Protein modification by small protein conjugation", "Protein modification by small protein conjugation or removal", "Protein modification by small protein removal", "Protein monoubiquitination", "Protein n linked glycosylation", "Protein neddylation", "Protein nitrosylation", "Protein o linked fucosylation", "Protein o linked glycosylation", "Protein o linked glycosylation via serine", "Protein o linked glycosylation via threonine", "Protein o linked mannosylation", "Protein oxidation", "Protein palmitoylation", "Protein peptidyl prolyl isomerization", "Protein poly adp ribosylation", "Protein polyglutamylation", "Protein polymerization", "Protein polyubiquitination", "Protein polyufmylation", "Protein processing", "Protein processing involved in protein targeting to mitochondrion", "Protein quality control for misfolded or incompletely synthesized proteins", "Protein refolding", "Protein repair", "Protein retention in er lumen", "Protein retention in golgi apparatus", "Protein stabilization", "Protein sumoylation", "Protein targeting", "Protein targeting to lysosome", "Protein targeting to membrane", "Protein targeting to mitochondrion", "Protein targeting to peroxisome", "Protein targeting to vacuole", "Protein tetramerization", "Protein transmembrane import into intracellular organelle", "Protein transmembrane transport", "Protein transport along microtubule", "Protein transport to vacuole involved in ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Protein transport within lipid bilayer", "Protein trimerization", "Protein ufmylation", "Proteoglycan biosynthetic process", "Proteoglycan metabolic process", "Proteolysis", "Proton transmembrane transport", "Proton transporting two sector atpase complex assembly", "Proton transporting v type atpase complex assembly", "Protoporphyrinogen ix biosynthetic process", "Protoporphyrinogen ix metabolic process", "Proximal distal pattern formation", "Proximal distal pattern formation involved in nephron development", "Proximal tubule development", "Pseudopodium organization", "Pseudouridine synthesis", "Pteridine containing compound biosynthetic process", "Pteridine containing compound metabolic process", "Pulmonary artery morphogenesis", "Pulmonary valve development", "Pulmonary valve morphogenesis", "Purine containing compound biosynthetic process", "Purine containing compound catabolic process", "Purine containing compound metabolic process", "Purine containing compound salvage", "Purine containing compound transmembrane transport", "Purine deoxyribonucleoside metabolic process", "Purine deoxyribonucleoside monophosphate catabolic process", "Purine deoxyribonucleoside monophosphate metabolic process", "Purine deoxyribonucleoside triphosphate metabolic process", "Purine deoxyribonucleotide biosynthetic process", "Purine deoxyribonucleotide catabolic process", "Purine deoxyribonucleotide metabolic process", "Purine nucleobase biosynthetic process", "Purine nucleobase metabolic process", "Purine nucleoside biosynthetic process", "Purine nucleoside catabolic process", "Purine nucleoside diphosphate biosynthetic process", "Purine nucleoside diphosphate catabolic process", "Purine nucleoside metabolic process", "Purine nucleoside monophosphate biosynthetic process", "Purine nucleoside monophosphate catabolic process", "Purine nucleoside monophosphate metabolic process", "Purine nucleoside triphosphate catabolic process", "Purine nucleotide catabolic process", "Purine nucleotide salvage", "Purine nucleotide transport", "Purine ribonucleoside catabolic process", "Purine ribonucleoside metabolic process", "Purine ribonucleoside salvage", "Purine ribonucleotide salvage", "Purinergic nucleotide receptor signaling pathway", "Putrescine metabolic process", "Pyramidal neuron development", "Pyramidal neuron differentiation", "Pyridine containing compound biosynthetic process", "Pyridine containing compound catabolic process", "Pyridine containing compound metabolic process", "Pyridine nucleotide biosynthetic process", "Pyridine nucleotide metabolic process", "Pyrimidine containing compound biosynthetic process", "Pyrimidine containing compound catabolic process", "Pyrimidine containing compound metabolic process", "Pyrimidine containing compound salvage", "Pyrimidine containing compound transmembrane transport", "Pyrimidine deoxyribonucleoside metabolic process", "Pyrimidine deoxyribonucleoside monophosphate biosynthetic process", "Pyrimidine deoxyribonucleoside monophosphate metabolic process", "Pyrimidine deoxyribonucleoside triphosphate metabolic process", "Pyrimidine deoxyribonucleotide biosynthetic process", "Pyrimidine deoxyribonucleotide metabolic process", "Pyrimidine dimer repair", "Pyrimidine nucleobase biosynthetic process", "Pyrimidine nucleobase catabolic process", "Pyrimidine nucleobase metabolic process", "Pyrimidine nucleoside catabolic process", "Pyrimidine nucleoside diphosphate biosynthetic process", "Pyrimidine nucleoside diphosphate metabolic process", "Pyrimidine nucleoside metabolic process", "Pyrimidine nucleoside monophosphate biosynthetic process", "Pyrimidine nucleoside monophosphate metabolic process", "Pyrimidine nucleoside transport", "Pyrimidine nucleoside triphosphate biosynthetic process", "Pyrimidine nucleoside triphosphate metabolic process", "Pyrimidine nucleotide catabolic process", "Pyrimidine nucleotide metabolic process", "Pyrimidine ribonucleoside diphosphate metabolic process", "Pyrimidine ribonucleoside monophosphate metabolic process", "Pyrimidine ribonucleoside triphosphate biosynthetic process", "Pyrimidine ribonucleoside triphosphate metabolic process", "Pyrimidine ribonucleotide biosynthetic process", "Pyrimidine ribonucleotide metabolic process", "Pyroptosis", "Pyruvate metabolic process", "Pyruvate transmembrane transport", "Pyruvate transport", "Quaternary ammonium group transport", "Quinone metabolic process", "R loop disassembly", "Rab protein signal transduction", "Rac protein signal transduction", "Radial glial cell differentiation", "Rap protein signal transduction", "Ras protein signal transduction", "Reactive nitrogen species metabolic process", "Reactive oxygen species biosynthetic process", "Reactive oxygen species metabolic process", "Receptor catabolic process", "Receptor clustering", "Receptor diffusion trapping", "Receptor internalization", "Receptor localization to synapse", "Receptor mediated endocytosis", "Receptor mediated endocytosis involved in cholesterol transport", "Receptor metabolic process", "Receptor recycling", "Receptor signaling pathway via stat", "Receptor transactivation", "Recognition of apoptotic cell", "Recombinational repair", "Reduction of food intake in response to dietary excess", "Reelin mediated signaling pathway", "Reflex", "Regeneration", "Regionalization", "Regulated exocytosis", "Regulation by virus of viral protein levels in host cell", "Regulation of 3 utr mediated mrna stabilization", "Regulation of acrosome reaction", "Regulation of actin cytoskeleton reorganization", "Regulation of actin filament based movement", "Regulation of actin filament based process", "Regulation of actin filament bundle assembly", "Regulation of actin filament length", "Regulation of actin filament organization", "Regulation of actin nucleation", "Regulation of action potential", "Regulation of activin receptor signaling pathway", "Regulation of actomyosin structure organization", "Regulation of acute inflammatory response", "Regulation of acute inflammatory response to antigenic stimulus", "Regulation of acyl coa biosynthetic process", "Regulation of adaptive immune response", "Regulation of adenylate cyclase activating g protein coupled receptor signaling pathway", "Regulation of adenylate cyclase activity", "Regulation of adherens junction organization", "Regulation of adiponectin secretion", "Regulation of adipose tissue development", "Regulation of aerobic respiration", "Regulation of alcohol biosynthetic process", "Regulation of alkaline phosphatase activity", "Regulation of alpha beta t cell activation", "Regulation of alpha beta t cell differentiation", "Regulation of alternative mrna splicing via spliceosome", "Regulation of amino acid transmembrane transport", "Regulation of amino acid transport", "Regulation of amyloid beta clearance", "Regulation of amyloid fibril formation", "Regulation of amyloid precursor protein catabolic process", "Regulation of anaphase promoting complex dependent catabolic process", "Regulation of anatomical structure morphogenesis", "Regulation of anatomical structure size", "Regulation of androgen receptor signaling pathway", "Regulation of angiotensin levels in blood", "Regulation of animal organ formation", "Regulation of animal organ morphogenesis", "Regulation of anion channel activity", "Regulation of anion transmembrane transport", "Regulation of anion transport", "Regulation of anoikis", "Regulation of antifungal innate immune response", "Regulation of antigen receptor mediated signaling pathway", "Regulation of apoptotic cell clearance", "Regulation of apoptotic dna fragmentation", "Regulation of apoptotic signaling pathway", "Regulation of appetite", "Regulation of arachidonic acid secretion", "Regulation of arp2 3 complex mediated actin nucleation", "Regulation of aspartic type endopeptidase activity involved in amyloid precursor protein catabolic process", "Regulation of aspartic type peptidase activity", "Regulation of astrocyte activation", "Regulation of astrocyte differentiation", "Regulation of asymmetric cell division", "Regulation of atp biosynthetic process", "Regulation of atp dependent activity", "Regulation of atp metabolic process", "Regulation of atpase coupled calcium transmembrane transporter activity", "Regulation of atrial cardiac muscle cell membrane repolarization", "Regulation of attachment of spindle microtubules to kinetochore", "Regulation of autophagic cell death", "Regulation of autophagosome maturation", "Regulation of autophagy", "Regulation of autophagy of mitochondrion", "Regulation of autophagy of mitochondrion in response to mitochondrial depolarization", "Regulation of axon diameter", "Regulation of axon guidance", "Regulation of axonogenesis", "Regulation of b cell activation", "Regulation of b cell apoptotic process", "Regulation of b cell differentiation", "Regulation of b cell mediated immunity", "Regulation of b cell proliferation", "Regulation of b cell receptor signaling pathway", "Regulation of barbed end actin filament capping", "Regulation of behavior", "Regulation of bicellular tight junction assembly", "Regulation of bile acid biosynthetic process", "Regulation of bile acid metabolic process", "Regulation of binding", "Regulation of biological process involved in symbiotic interaction", "Regulation of biomineralization", "Regulation of blood brain barrier permeability", "Regulation of blood circulation", "Regulation of blood pressure", "Regulation of blood vessel remodeling", "Regulation of bmp signaling pathway", "Regulation of body fluid levels", "Regulation of bone mineralization", "Regulation of bone mineralization involved in bone maturation", "Regulation of bone remodeling", "Regulation of bone resorption", "Regulation of branching involved in lung morphogenesis", "Regulation of branching morphogenesis of a nerve", "Regulation of brown fat cell differentiation", "Regulation of calcineurin mediated signaling", "Regulation of calcium ion dependent exocytosis", "Regulation of calcium ion export across plasma membrane", "Regulation of calcium ion import", "Regulation of calcium ion transmembrane transport", "Regulation of calcium ion transmembrane transporter activity", "Regulation of calcium ion transport", "Regulation of calcium ion transport into cytosol", "Regulation of calcium mediated signaling", "Regulation of camp dependent protein kinase activity", "Regulation of camp mediated signaling", "Regulation of canonical wnt signaling pathway", "Regulation of carbohydrate biosynthetic process", "Regulation of carbohydrate catabolic process", "Regulation of carbohydrate metabolic process", "Regulation of cardiac conduction", "Regulation of cardiac muscle adaptation", "Regulation of cardiac muscle cell action potential", "Regulation of cardiac muscle cell action potential involved in regulation of contraction", "Regulation of cardiac muscle cell differentiation", "Regulation of cardiac muscle cell membrane potential", "Regulation of cardiac muscle cell membrane repolarization", "Regulation of cardiac muscle cell proliferation", "Regulation of cardiac muscle contraction", "Regulation of cardiac muscle contraction by calcium ion signaling", "Regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion", "Regulation of cardioblast differentiation", "Regulation of cardiocyte differentiation", "Regulation of cartilage development", "Regulation of catabolic process", "Regulation of catecholamine metabolic process", "Regulation of cation channel activity", "Regulation of cation transmembrane transport", "Regulation of caveolin mediated endocytosis", "Regulation of cd4 positive alpha beta t cell activation", "Regulation of cd4 positive alpha beta t cell differentiation", "Regulation of cd8 positive alpha beta t cell activation", "Regulation of cdc42 protein signal transduction", "Regulation of cell activation", "Regulation of cell adhesion", "Regulation of cell adhesion mediated by integrin", "Regulation of cell aging", "Regulation of cell cell adhesion", "Regulation of cell cell adhesion mediated by cadherin", "Regulation of cell cell adhesion mediated by integrin", "Regulation of cell communication by electrical coupling", "Regulation of cell communication by electrical coupling involved in cardiac conduction", "Regulation of cell cycle", "Regulation of cell cycle checkpoint", "Regulation of cell cycle g1 s phase transition", "Regulation of cell cycle g2 m phase transition", "Regulation of cell cycle phase transition", "Regulation of cell cycle process", "Regulation of cell death", "Regulation of cell development", "Regulation of cell differentiation", "Regulation of cell division", "Regulation of cell growth involved in cardiac muscle cell development", "Regulation of cell junction assembly", "Regulation of cell killing", "Regulation of cell matrix adhesion", "Regulation of cell maturation", "Regulation of cell migration involved in sprouting angiogenesis", "Regulation of cell morphogenesis", "Regulation of cell morphogenesis involved in differentiation", "Regulation of cell population proliferation", "Regulation of cell projection assembly", "Regulation of cell projection organization", "Regulation of cell projection size", "Regulation of cell shape", "Regulation of cell size", "Regulation of cell substrate adhesion", "Regulation of cell substrate junction organization", "Regulation of cellular amide metabolic process", "Regulation of cellular amine metabolic process", "Regulation of cellular amino acid metabolic process", "Regulation of cellular carbohydrate catabolic process", "Regulation of cellular carbohydrate metabolic process", "Regulation of cellular component biogenesis", "Regulation of cellular component movement", "Regulation of cellular component size", "Regulation of cellular extravasation", "Regulation of cellular ketone metabolic process", "Regulation of cellular localization", "Regulation of cellular macromolecule biosynthetic process", "Regulation of cellular ph", "Regulation of cellular protein catabolic process", "Regulation of cellular respiration", "Regulation of cellular response to growth factor stimulus", "Regulation of cellular response to heat", "Regulation of cellular response to hypoxia", "Regulation of cellular response to insulin stimulus", "Regulation of cellular response to osmotic stress", "Regulation of cellular response to stress", "Regulation of cellular response to transforming growth factor beta stimulus", "Regulation of cellular response to vascular endothelial growth factor stimulus", "Regulation of centriole replication", "Regulation of centromere complex assembly", "Regulation of centrosome cycle", "Regulation of chaperone mediated autophagy", "Regulation of chemokine mediated signaling pathway", "Regulation of chemotaxis", "Regulation of chloride transport", "Regulation of cholesterol biosynthetic process", "Regulation of cholesterol efflux", "Regulation of cholesterol esterification", "Regulation of cholesterol metabolic process", "Regulation of chondrocyte development", "Regulation of chondrocyte differentiation", "Regulation of chromatin assembly", "Regulation of chromatin assembly or disassembly", "Regulation of chromatin binding", "Regulation of chromatin organization", "Regulation of chromosome condensation", "Regulation of chromosome organization", "Regulation of chromosome segregation", "Regulation of chromosome separation", "Regulation of cilium assembly", "Regulation of cilium beat frequency", "Regulation of cilium beat frequency involved in ciliary motility", "Regulation of cilium dependent cell motility", "Regulation of cilium movement", "Regulation of circadian rhythm", "Regulation of clathrin dependent endocytosis", "Regulation of coagulation", "Regulation of collagen fibril organization", "Regulation of collagen metabolic process", "Regulation of collateral sprouting", "Regulation of complement activation", "Regulation of complement dependent cytotoxicity", "Regulation of connective tissue replacement", "Regulation of core promoter binding", "Regulation of cyclase activity", "Regulation of cyclic nucleotide phosphodiesterase activity", "Regulation of cyclin dependent protein kinase activity", "Regulation of cysteine type endopeptidase activity", "Regulation of cysteine type endopeptidase activity involved in apoptotic signaling pathway", "Regulation of cysteine type endopeptidase activity involved in execution phase of apoptosis", "Regulation of cytokinesis", "Regulation of cytoplasmic mrna processing body assembly", "Regulation of cytoplasmic translation", "Regulation of cytoplasmic translational elongation", "Regulation of cytoplasmic translational initiation", "Regulation of cytoplasmic transport", "Regulation of cytoskeleton organization", "Regulation of cytosolic calcium ion concentration", "Regulation of deacetylase activity", "Regulation of defense response", "Regulation of defense response to bacterium", "Regulation of defense response to fungus", "Regulation of defense response to virus", "Regulation of defense response to virus by host", "Regulation of delayed rectifier potassium channel activity", "Regulation of dendrite development", "Regulation of dendrite extension", "Regulation of dendrite morphogenesis", "Regulation of dendritic cell chemotaxis", "Regulation of dendritic cell differentiation", "Regulation of dendritic spine development", "Regulation of dendritic spine maintenance", "Regulation of dendritic spine morphogenesis", "Regulation of deoxyribonuclease activity", "Regulation of dephosphorylation", "Regulation of development heterochronic", "Regulation of developmental growth", "Regulation of digestive system process", "Regulation of dna binding", "Regulation of dna binding transcription factor activity", "Regulation of dna biosynthetic process", "Regulation of dna catabolic process", "Regulation of dna damage checkpoint", "Regulation of dna damage response signal transduction by p53 class mediator", "Regulation of dna damage response signal transduction by p53 class mediator resulting in transcription of p21 class mediator", "Regulation of dna demethylation", "Regulation of dna dependent dna replication", "Regulation of dna dependent dna replication initiation", "Regulation of dna directed dna polymerase activity", "Regulation of dna duplex unwinding", "Regulation of dna helicase activity", "Regulation of dna ligation", "Regulation of dna metabolic process", "Regulation of dna methylation", "Regulation of dna methylation dependent heterochromatin assembly", "Regulation of dna primase activity", "Regulation of dna recombination", "Regulation of dna repair", "Regulation of dna replication", "Regulation of dna strand elongation", "Regulation of dna templated transcription elongation", "Regulation of dna templated transcription in response to stress", "Regulation of dna templated transcription initiation", "Regulation of dna topoisomerase atp hydrolyzing activity", "Regulation of dopamine receptor signaling pathway", "Regulation of dopamine uptake involved in synaptic transmission", "Regulation of dopaminergic neuron differentiation", "Regulation of double strand break repair", "Regulation of double strand break repair via homologous recombination", "Regulation of double strand break repair via nonhomologous end joining", "Regulation of early endosome to late endosome transport", "Regulation of electron transfer activity", "Regulation of embryonic development", "Regulation of enamel mineralization", "Regulation of endocrine process", "Regulation of endocytic recycling", "Regulation of endocytosis", "Regulation of endodeoxyribonuclease activity", "Regulation of endodermal cell differentiation", "Regulation of endoplasmic reticulum stress induced intrinsic apoptotic signaling pathway", "Regulation of endoplasmic reticulum tubular network organization", "Regulation of endoplasmic reticulum unfolded protein response", "Regulation of endothelial cell chemotaxis", "Regulation of endothelial cell development", "Regulation of endothelial cell differentiation", "Regulation of endothelial cell migration", "Regulation of entry of bacterium into host cell", "Regulation of epidermal growth factor activated receptor activity", "Regulation of epidermis development", "Regulation of epithelial cell apoptotic process", "Regulation of epithelial cell differentiation", "Regulation of epithelial cell differentiation involved in kidney development", "Regulation of epithelial cell migration", "Regulation of epithelial cell proliferation involved in lung morphogenesis", "Regulation of epithelial to mesenchymal transition", "Regulation of er associated ubiquitin dependent protein catabolic process", "Regulation of er to golgi vesicle mediated transport", "Regulation of erad pathway", "Regulation of erbb signaling pathway", "Regulation of erythrocyte differentiation", "Regulation of establishment of planar polarity", "Regulation of establishment of protein localization", "Regulation of establishment of protein localization to chromosome", "Regulation of establishment of protein localization to mitochondrion", "Regulation of establishment or maintenance of cell polarity", "Regulation of excretion", "Regulation of execution phase of apoptosis", "Regulation of exit from mitosis", "Regulation of exocytosis", "Regulation of exosomal secretion", "Regulation of extent of cell growth", "Regulation of extracellular matrix assembly", "Regulation of extracellular matrix disassembly", "Regulation of extracellular matrix organization", "Regulation of extrinsic apoptotic signaling pathway", "Regulation of extrinsic apoptotic signaling pathway in absence of ligand", "Regulation of extrinsic apoptotic signaling pathway via death domain receptors", "Regulation of fat cell differentiation", "Regulation of fat cell proliferation", "Regulation of fatty acid beta oxidation", "Regulation of fatty acid biosynthetic process", "Regulation of fatty acid metabolic process", "Regulation of fatty acid oxidation", "Regulation of fatty acid transport", "Regulation of fc gamma receptor signaling pathway involved in phagocytosis", "Regulation of fc receptor mediated stimulatory signaling pathway", "Regulation of feeding behavior", "Regulation of fertilization", "Regulation of fibroblast growth factor receptor signaling pathway", "Regulation of fibroblast migration", "Regulation of filopodium assembly", "Regulation of focal adhesion disassembly", "Regulation of g protein coupled receptor signaling pathway", "Regulation of g0 to g1 transition", "Regulation of gamma aminobutyric acid secretion", "Regulation of gastric acid secretion", "Regulation of gastrulation", "Regulation of gene expression by genomic imprinting", "Regulation of gene expression epigenetic", "Regulation of gene silencing by rna", "Regulation of generation of precursor metabolites and energy", "Regulation of genetic imprinting", "Regulation of germ cell proliferation", "Regulation of germinal center formation", "Regulation of glial cell apoptotic process", "Regulation of glial cell differentiation", "Regulation of glial cell migration", "Regulation of glial cell proliferation", "Regulation of gliogenesis", "Regulation of glucagon secretion", "Regulation of glucan biosynthetic process", "Regulation of glucocorticoid biosynthetic process", "Regulation of glucocorticoid metabolic process", "Regulation of glucocorticoid receptor signaling pathway", "Regulation of glucocorticoid secretion", "Regulation of gluconeogenesis", "Regulation of glucose import", "Regulation of glucose metabolic process", "Regulation of glucose transmembrane transport", "Regulation of glucosylceramidase activity", "Regulation of glutamate receptor clustering", "Regulation of glutamate secretion", "Regulation of glutamine family amino acid metabolic process", "Regulation of glycogen catabolic process", "Regulation of glycogen metabolic process", "Regulation of glycogen starch synthase activity", "Regulation of glycolytic process", "Regulation of glycoprotein metabolic process", "Regulation of golgi organization", "Regulation of golgi to plasma membrane protein transport", "Regulation of gonad development", "Regulation of granulocyte chemotaxis", "Regulation of granulocyte differentiation", "Regulation of growth", "Regulation of growth rate", "Regulation of gtp binding", "Regulation of gtpase activity", "Regulation of guanyl nucleotide exchange factor activity", "Regulation of hair cycle", "Regulation of hair follicle development", "Regulation of heart contraction", "Regulation of heart growth", "Regulation of heart rate", "Regulation of heart rate by cardiac conduction", "Regulation of heart rate by chemical signal", "Regulation of heat generation", "Regulation of helicase activity", "Regulation of hematopoietic progenitor cell differentiation", "Regulation of hematopoietic stem cell differentiation", "Regulation of hematopoietic stem cell proliferation", "Regulation of hemoglobin biosynthetic process", "Regulation of hemopoiesis", "Regulation of hepatic stellate cell activation", "Regulation of hepatocyte proliferation", "Regulation of heterotypic cell cell adhesion", "Regulation of hexokinase activity", "Regulation of high voltage gated calcium channel activity", "Regulation of hippo signaling", "Regulation of histamine secretion by mast cell", "Regulation of histone deacetylase activity", "Regulation of histone deacetylation", "Regulation of histone h2b ubiquitination", "Regulation of histone h3 k14 acetylation", "Regulation of histone h3 k27 methylation", "Regulation of histone h3 k36 methylation", "Regulation of histone h3 k4 methylation", "Regulation of histone h3 k9 methylation", "Regulation of histone h3 k9 trimethylation", "Regulation of histone h4 acetylation", "Regulation of histone h4 k16 acetylation", "Regulation of histone methylation", "Regulation of histone modification", "Regulation of histone phosphorylation", "Regulation of histone ubiquitination", "Regulation of homophilic cell adhesion", "Regulation of homotypic cell cell adhesion", "Regulation of hormone biosynthetic process", "Regulation of hormone levels", "Regulation of hormone metabolic process", "Regulation of hormone secretion", "Regulation of humoral immune response", "Regulation of hyaluronan biosynthetic process", "Regulation of hydrogen peroxide biosynthetic process", "Regulation of hydrogen peroxide mediated programmed cell death", "Regulation of hydrogen peroxide metabolic process", "Regulation of hydrolase activity", "Regulation of i kappab phosphorylation", "Regulation of icosanoid secretion", "Regulation of immune effector process", "Regulation of immune response", "Regulation of immune system process", "Regulation of immunoglobulin production", "Regulation of inclusion body assembly", "Regulation of inflammatory response", "Regulation of inflammatory response to antigenic stimulus", "Regulation of innate immune response", "Regulation of inositol 1 4 5 trisphosphate sensitive calcium release channel activity", "Regulation of insulin like growth factor receptor signaling pathway", "Regulation of insulin receptor signaling pathway", "Regulation of insulin secretion", "Regulation of insulin secretion involved in cellular response to glucose stimulus", "Regulation of integrin activation", "Regulation of integrin mediated signaling pathway", "Regulation of interleukin 1 mediated signaling pathway", "Regulation of interleukin 6 mediated signaling pathway", "Regulation of intestinal absorption", "Regulation of intracellular estrogen receptor signaling pathway", "Regulation of intracellular lipid transport", "Regulation of intracellular protein transport", "Regulation of intracellular signal transduction", "Regulation of intracellular steroid hormone receptor signaling pathway", "Regulation of intracellular transport", "Regulation of intrinsic apoptotic signaling pathway", "Regulation of intrinsic apoptotic signaling pathway by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage", "Regulation of intrinsic apoptotic signaling pathway in response to dna damage by p53 class mediator", "Regulation of intrinsic apoptotic signaling pathway in response to osmotic stress", "Regulation of inward rectifier potassium channel activity", "Regulation of ion transmembrane transport", "Regulation of ion transport", "Regulation of ire1 mediated unfolded protein response", "Regulation of isomerase activity", "Regulation of isotype switching", "Regulation of jnk cascade", "Regulation of jun kinase activity", "Regulation of keratinocyte differentiation", "Regulation of keratinocyte migration", "Regulation of keratinocyte proliferation", "Regulation of ketone biosynthetic process", "Regulation of kidney development", "Regulation of l glutamate import across plasma membrane", "Regulation of lamellipodium assembly", "Regulation of lamellipodium morphogenesis", "Regulation of lamellipodium organization", "Regulation of leukocyte apoptotic process", "Regulation of leukocyte chemotaxis", "Regulation of leukocyte degranulation", "Regulation of leukocyte differentiation", "Regulation of leukocyte mediated cytotoxicity", "Regulation of leukocyte mediated immunity", "Regulation of leukocyte migration", "Regulation of leukocyte proliferation", "Regulation of ligase activity", "Regulation of lipase activity", "Regulation of lipid biosynthetic process", "Regulation of lipid catabolic process", "Regulation of lipid kinase activity", "Regulation of lipid localization", "Regulation of lipid metabolic process", "Regulation of lipid storage", "Regulation of lipid transport", "Regulation of lipid transporter activity", "Regulation of lipophagy", "Regulation of lipopolysaccharide mediated signaling pathway", "Regulation of lipoprotein lipase activity", "Regulation of lipoprotein metabolic process", "Regulation of lipoprotein particle clearance", "Regulation of locomotion involved in locomotory behavior", "Regulation of long chain fatty acid import across plasma membrane", "Regulation of long chain fatty acid import into cell", "Regulation of long term neuronal synaptic plasticity", "Regulation of long term synaptic depression", "Regulation of long term synaptic potentiation", "Regulation of low density lipoprotein particle clearance", "Regulation of lyase activity", "Regulation of lymphocyte activation", "Regulation of lymphocyte apoptotic process", "Regulation of lymphocyte chemotaxis", "Regulation of lymphocyte differentiation", "Regulation of lymphocyte mediated immunity", "Regulation of lymphocyte migration", "Regulation of lymphoid progenitor cell differentiation", "Regulation of lysosomal lumen ph", "Regulation of lysosomal protein catabolic process", "Regulation of lysosome organization", "Regulation of macroautophagy", "Regulation of macrophage activation", "Regulation of macrophage apoptotic process", "Regulation of macrophage chemotaxis", "Regulation of macrophage derived foam cell differentiation", "Regulation of macrophage differentiation", "Regulation of macrophage migration", "Regulation of macrophage proliferation", "Regulation of maintenance of sister chromatid cohesion", "Regulation of male gonad development", "Regulation of mammary gland epithelial cell proliferation", "Regulation of map kinase activity", "Regulation of mast cell activation", "Regulation of mast cell activation involved in immune response", "Regulation of matrix metallopeptidase secretion", "Regulation of mda 5 signaling pathway", "Regulation of megakaryocyte differentiation", "Regulation of meiotic cell cycle", "Regulation of meiotic cell cycle phase transition", "Regulation of meiotic nuclear division", "Regulation of melanocyte differentiation", "Regulation of membrane depolarization", "Regulation of membrane depolarization during action potential", "Regulation of membrane depolarization during cardiac muscle cell action potential", "Regulation of membrane invagination", "Regulation of membrane lipid distribution", "Regulation of membrane permeability", "Regulation of membrane potential", "Regulation of membrane protein ectodomain proteolysis", "Regulation of membrane repolarization", "Regulation of membrane repolarization during action potential", "Regulation of membrane repolarization during cardiac muscle cell action potential", "Regulation of membrane tubulation", "Regulation of mesenchymal cell proliferation", "Regulation of mesenchymal stem cell differentiation", "Regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis", "Regulation of mesoderm development", "Regulation of metal ion transport", "Regulation of metalloendopeptidase activity", "Regulation of metallopeptidase activity", "Regulation of metanephros development", "Regulation of metaphase plate congression", "Regulation of microglial cell activation", "Regulation of microtubule based movement", "Regulation of microtubule based process", "Regulation of microtubule binding", "Regulation of microtubule cytoskeleton organization", "Regulation of microtubule depolymerization", "Regulation of microtubule nucleation", "Regulation of microtubule polymerization", "Regulation of microtubule polymerization or depolymerization", "Regulation of microvillus assembly", "Regulation of microvillus length", "Regulation of microvillus organization", "Regulation of mirna catabolic process", "Regulation of mirna metabolic process", "Regulation of mirna transcription", "Regulation of mitochondrial atp synthesis coupled electron transport", "Regulation of mitochondrial dna replication", "Regulation of mitochondrial electron transport nadh to ubiquinone", "Regulation of mitochondrial fission", "Regulation of mitochondrial fusion", "Regulation of mitochondrial gene expression", "Regulation of mitochondrial membrane permeability", "Regulation of mitochondrial membrane permeability involved in apoptotic process", "Regulation of mitochondrial membrane potential", "Regulation of mitochondrial mrna stability", "Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway", "Regulation of mitochondrial rna catabolic process", "Regulation of mitochondrion organization", "Regulation of mitophagy", "Regulation of mitotic cell cycle", "Regulation of mitotic cell cycle phase transition", "Regulation of mitotic cell cycle spindle assembly checkpoint", "Regulation of mitotic centrosome separation", "Regulation of mitotic cytokinesis", "Regulation of mitotic nuclear division", "Regulation of mitotic recombination", "Regulation of mitotic sister chromatid segregation", "Regulation of mitotic spindle assembly", "Regulation of modification of postsynaptic structure", "Regulation of modification of synaptic structure", "Regulation of monocyte chemotaxis", "Regulation of monocyte differentiation", "Regulation of monocyte extravasation", "Regulation of mononuclear cell migration", "Regulation of monooxygenase activity", "Regulation of morphogenesis of a branching structure", "Regulation of morphogenesis of an epithelium", "Regulation of motor neuron apoptotic process", "Regulation of mrna 3 end processing", "Regulation of mrna binding", "Regulation of mrna catabolic process", "Regulation of mrna export from nucleus", "Regulation of mrna metabolic process", "Regulation of mrna polyadenylation", "Regulation of mrna processing", "Regulation of mrna splicing via spliceosome", "Regulation of mucus secretion", "Regulation of multicellular organism growth", "Regulation of multicellular organismal development", "Regulation of muscle adaptation", "Regulation of muscle cell differentiation", "Regulation of muscle contraction", "Regulation of muscle hypertrophy", "Regulation of muscle organ development", "Regulation of muscle system process", "Regulation of myelination", "Regulation of myeloid cell apoptotic process", "Regulation of myeloid cell differentiation", "Regulation of myeloid leukocyte differentiation", "Regulation of myeloid leukocyte mediated immunity", "Regulation of myoblast differentiation", "Regulation of myoblast fusion", "Regulation of myoblast proliferation", "Regulation of myosin light chain phosphatase activity", "Regulation of myotube differentiation", "Regulation of nad p h oxidase activity", "Regulation of nadp metabolic process", "Regulation of natural killer cell activation", "Regulation of natural killer cell mediated immunity", "Regulation of necrotic cell death", "Regulation of nervous system development", "Regulation of nervous system process", "Regulation of neural precursor cell proliferation", "Regulation of neuroblast proliferation", "Regulation of neurogenesis", "Regulation of neuromuscular junction development", "Regulation of neuron differentiation", "Regulation of neuron migration", "Regulation of neuron projection arborization", "Regulation of neuron projection development", "Regulation of neuron projection regeneration", "Regulation of neuronal action potential", "Regulation of neuronal synaptic plasticity", "Regulation of neurotransmitter levels", "Regulation of neurotransmitter receptor activity", "Regulation of neurotransmitter transport", "Regulation of neurotransmitter uptake", "Regulation of neurotrophin trk receptor signaling pathway", "Regulation of neutrophil activation", "Regulation of neutrophil chemotaxis", "Regulation of neutrophil degranulation", "Regulation of neutrophil migration", "Regulation of nik nf kappab signaling", "Regulation of nitric oxide mediated signal transduction", "Regulation of nitric oxide metabolic process", "Regulation of nitric oxide synthase activity", "Regulation of nk t cell activation", "Regulation of nk t cell differentiation", "Regulation of nmda receptor activity", "Regulation of non canonical wnt signaling pathway", "Regulation of non motile cilium assembly", "Regulation of notch signaling pathway", "Regulation of nuclear cell cycle dna replication", "Regulation of nuclear division", "Regulation of nuclear transcribed mrna catabolic process deadenylation dependent decay", "Regulation of nuclear transcribed mrna catabolic process nonsense mediated decay", "Regulation of nuclear transcribed mrna poly a tail shortening", "Regulation of nuclease activity", "Regulation of nucleobase containing compound transport", "Regulation of nucleocytoplasmic transport", "Regulation of nucleotide binding oligomerization domain containing 2 signaling pathway", "Regulation of nucleotide binding oligomerization domain containing signaling pathway", "Regulation of nucleotide biosynthetic process", "Regulation of nucleotide metabolic process", "Regulation of oligodendrocyte differentiation", "Regulation of oocyte maturation", "Regulation of opsonization", "Regulation of organ growth", "Regulation of organelle assembly", "Regulation of organelle organization", "Regulation of organelle transport along microtubule", "Regulation of organic acid transport", "Regulation of ossification", "Regulation of osteoblast differentiation", "Regulation of osteoblast proliferation", "Regulation of osteoclast development", "Regulation of osteoclast differentiation", "Regulation of oxidative phosphorylation", "Regulation of oxidative stress induced cell death", "Regulation of oxidative stress induced intrinsic apoptotic signaling pathway", "Regulation of oxidoreductase activity", "Regulation of p38mapk cascade", "Regulation of pancreatic juice secretion", "Regulation of pattern recognition receptor signaling pathway", "Regulation of penile erection", "Regulation of peptidase activity", "Regulation of peptide transport", "Regulation of peptidyl cysteine s nitrosylation", "Regulation of peptidyl lysine acetylation", "Regulation of peptidyl serine phosphorylation", "Regulation of peptidyl serine phosphorylation of stat protein", "Regulation of peptidyl threonine phosphorylation", "Regulation of peptidyl tyrosine phosphorylation", "Regulation of perk mediated unfolded protein response", "Regulation of peroxisome proliferator activated receptor signaling pathway", "Regulation of ph", "Regulation of phagocytosis", "Regulation of phenotypic switching", "Regulation of phosphatase activity", "Regulation of phosphatidylcholine biosynthetic process", "Regulation of phosphatidylcholine metabolic process", "Regulation of phosphatidylinositol 3 kinase activity", "Regulation of phosphatidylinositol 3 kinase signaling", "Regulation of phospholipase a2 activity", "Regulation of phospholipase activity", "Regulation of phospholipase c activity", "Regulation of phospholipid biosynthetic process", "Regulation of phospholipid catabolic process", "Regulation of phospholipid metabolic process", "Regulation of phospholipid translocation", "Regulation of phospholipid transport", "Regulation of phosphoprotein phosphatase activity", "Regulation of phosphorus metabolic process", "Regulation of pigment cell differentiation", "Regulation of pigmentation", "Regulation of pinocytosis", "Regulation of plasma lipoprotein particle levels", "Regulation of plasma membrane organization", "Regulation of plasminogen activation", "Regulation of platelet activation", "Regulation of platelet aggregation", "Regulation of platelet derived growth factor receptor beta signaling pathway", "Regulation of platelet derived growth factor receptor signaling pathway", "Regulation of podosome assembly", "Regulation of polysaccharide metabolic process", "Regulation of positive chemotaxis", "Regulation of post translational protein modification", "Regulation of postsynapse organization", "Regulation of postsynaptic cytosolic calcium ion concentration", "Regulation of postsynaptic density organization", "Regulation of postsynaptic membrane neurotransmitter receptor levels", "Regulation of postsynaptic membrane potential", "Regulation of postsynaptic neurotransmitter receptor internalization", "Regulation of potassium ion export across plasma membrane", "Regulation of potassium ion import", "Regulation of potassium ion transmembrane transporter activity", "Regulation of potassium ion transport", "Regulation of presynapse organization", "Regulation of presynaptic cytosolic calcium ion concentration", "Regulation of pro b cell differentiation", "Regulation of production of molecular mediator of immune response", "Regulation of production of small rna involved in gene silencing by rna", "Regulation of programmed necrotic cell death", "Regulation of prostaglandin secretion", "Regulation of proteasomal protein catabolic process", "Regulation of proteasomal ubiquitin dependent protein catabolic process", "Regulation of protein acetylation", "Regulation of protein adp ribosylation", "Regulation of protein autophosphorylation", "Regulation of protein autoubiquitination", "Regulation of protein binding", "Regulation of protein catabolic process", "Regulation of protein catabolic process in the vacuole", "Regulation of protein complex stability", "Regulation of protein containing complex assembly", "Regulation of protein containing complex disassembly", "Regulation of protein deacetylation", "Regulation of protein dephosphorylation", "Regulation of protein depolymerization", "Regulation of protein deubiquitination", "Regulation of protein exit from endoplasmic reticulum", "Regulation of protein export from nucleus", "Regulation of protein folding", "Regulation of protein glycosylation", "Regulation of protein import", "Regulation of protein k63 linked ubiquitination", "Regulation of protein kinase a signaling", "Regulation of protein kinase activity", "Regulation of protein kinase c activity", "Regulation of protein kinase c signaling", "Regulation of protein lipidation", "Regulation of protein localization", "Regulation of protein localization to cell cortex", "Regulation of protein localization to cell periphery", "Regulation of protein localization to cell surface", "Regulation of protein localization to centrosome", "Regulation of protein localization to chromatin", "Regulation of protein localization to chromosome telomeric region", "Regulation of protein localization to cilium", "Regulation of protein localization to endosome", "Regulation of protein localization to membrane", "Regulation of protein localization to nucleolus", "Regulation of protein localization to nucleus", "Regulation of protein localization to plasma membrane", "Regulation of protein localization to synapse", "Regulation of protein maturation", "Regulation of protein modification by small protein conjugation or removal", "Regulation of protein modification process", "Regulation of protein monoubiquitination", "Regulation of protein neddylation", "Regulation of protein phosphorylation", "Regulation of protein polymerization", "Regulation of protein polyubiquitination", "Regulation of protein secretion", "Regulation of protein serine threonine kinase activity", "Regulation of protein stability", "Regulation of protein sumoylation", "Regulation of protein targeting", "Regulation of protein targeting to membrane", "Regulation of protein tyrosine kinase activity", "Regulation of protein tyrosine phosphatase activity", "Regulation of proteolysis", "Regulation of proton transport", "Regulation of rab protein signal transduction", "Regulation of rac protein signal transduction", "Regulation of ras protein signal transduction", "Regulation of reactive oxygen species biosynthetic process", "Regulation of reactive oxygen species metabolic process", "Regulation of receptor binding", "Regulation of receptor catabolic process", "Regulation of receptor clustering", "Regulation of receptor internalization", "Regulation of receptor localization to synapse", "Regulation of receptor mediated endocytosis", "Regulation of receptor mediated endocytosis involved in cholesterol transport", "Regulation of receptor recycling", "Regulation of receptor signaling pathway via stat", "Regulation of regulated secretory pathway", "Regulation of relaxation of muscle", "Regulation of release of cytochrome c from mitochondria", "Regulation of release of sequestered calcium ion into cytosol", "Regulation of removal of superoxide radicals", "Regulation of renal system process", "Regulation of reproductive process", "Regulation of respiratory burst", "Regulation of respiratory gaseous exchange", "Regulation of respiratory gaseous exchange by nervous system process", "Regulation of respiratory system process", "Regulation of response to biotic stimulus", "Regulation of response to cytokine stimulus", "Regulation of response to dna damage stimulus", "Regulation of response to endoplasmic reticulum stress", "Regulation of response to external stimulus", "Regulation of response to extracellular stimulus", "Regulation of response to food", "Regulation of response to interferon gamma", "Regulation of response to osmotic stress", "Regulation of response to oxidative stress", "Regulation of response to reactive oxygen species", "Regulation of response to stress", "Regulation of response to tumor cell", "Regulation of response to wounding", "Regulation of retinal ganglion cell axon guidance", "Regulation of retinoic acid receptor signaling pathway", "Regulation of retrograde protein transport er to cytosol", "Regulation of retrograde transport endosome to golgi", "Regulation of rho dependent protein serine threonine kinase activity", "Regulation of rho protein signal transduction", "Regulation of rhodopsin mediated signaling pathway", "Regulation of ribonuclease activity", "Regulation of ribosome biogenesis", "Regulation of rig i signaling pathway", "Regulation of rna binding", "Regulation of rna export from nucleus", "Regulation of rna polymerase ii regulatory region sequence specific dna binding", "Regulation of rna polymerase ii transcription preinitiation complex assembly", "Regulation of rna splicing", "Regulation of rrna processing", "Regulation of ruffle assembly", "Regulation of ryanodine sensitive calcium release channel activity", "Regulation of sarcomere organization", "Regulation of secondary heart field cardioblast proliferation", "Regulation of secondary metabolic process", "Regulation of secretion", "Regulation of sequestering of triglyceride", "Regulation of sequestering of zinc ion", "Regulation of short term neuronal synaptic plasticity", "Regulation of signal transduction by p53 class mediator", "Regulation of signaling receptor activity", "Regulation of sister chromatid cohesion", "Regulation of skeletal muscle adaptation", "Regulation of skeletal muscle cell differentiation", "Regulation of skeletal muscle cell proliferation", "Regulation of skeletal muscle contraction", "Regulation of skeletal muscle contraction by calcium ion signaling", "Regulation of skeletal muscle fiber development", "Regulation of skeletal muscle tissue development", "Regulation of smad protein complex assembly", "Regulation of smad protein signal transduction", "Regulation of small gtpase mediated signal transduction", "Regulation of small molecule metabolic process", "Regulation of smooth muscle cell chemotaxis", "Regulation of smooth muscle cell differentiation", "Regulation of smooth muscle contraction", "Regulation of smoothened signaling pathway", "Regulation of smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Regulation of snrna transcription by rna polymerase ii", "Regulation of sodium ion transmembrane transport", "Regulation of sodium ion transport", "Regulation of sodium proton antiporter activity", "Regulation of sphingolipid biosynthetic process", "Regulation of spindle assembly", "Regulation of spindle organization", "Regulation of spontaneous synaptic transmission", "Regulation of sprouting angiogenesis", "Regulation of srebp signaling pathway", "Regulation of stem cell differentiation", "Regulation of stem cell population maintenance", "Regulation of stem cell proliferation", "Regulation of steroid biosynthetic process", "Regulation of steroid hormone biosynthetic process", "Regulation of steroid hormone secretion", "Regulation of steroid metabolic process", "Regulation of sterol transport", "Regulation of store operated calcium channel activity", "Regulation of stress activated protein kinase signaling cascade", "Regulation of stress granule assembly", "Regulation of striated muscle cell differentiation", "Regulation of striated muscle contraction", "Regulation of substrate adhesion dependent cell spreading", "Regulation of sulfur metabolic process", "Regulation of superoxide anion generation", "Regulation of superoxide dismutase activity", "Regulation of superoxide metabolic process", "Regulation of supramolecular fiber organization", "Regulation of synapse assembly", "Regulation of synapse maturation", "Regulation of synapse structural plasticity", "Regulation of synapse structure or activity", "Regulation of synaptic plasticity", "Regulation of synaptic transmission dopaminergic", "Regulation of synaptic transmission gabaergic", "Regulation of synaptic transmission glutamatergic", "Regulation of synaptic vesicle clustering", "Regulation of synaptic vesicle endocytosis", "Regulation of synaptic vesicle exocytosis", "Regulation of synaptic vesicle priming", "Regulation of synaptic vesicle recycling", "Regulation of syncytium formation by plasma membrane fusion", "Regulation of system process", "Regulation of systemic arterial blood pressure", "Regulation of systemic arterial blood pressure by circulatory renin angiotensin", "Regulation of systemic arterial blood pressure by endothelin", "Regulation of systemic arterial blood pressure by hormone", "Regulation of systemic arterial blood pressure by norepinephrine epinephrine", "Regulation of systemic arterial blood pressure by renin angiotensin", "Regulation of systemic arterial blood pressure mediated by a chemical signal", "Regulation of t cell activation", "Regulation of t cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "Regulation of t cell apoptotic process", "Regulation of t cell chemotaxis", "Regulation of t cell differentiation", "Regulation of t cell differentiation in thymus", "Regulation of t cell mediated cytotoxicity", "Regulation of t cell mediated immune response to tumor cell", "Regulation of t cell mediated immunity", "Regulation of t cell migration", "Regulation of t cell proliferation", "Regulation of t cell receptor signaling pathway", "Regulation of t circle formation", "Regulation of t helper 1 cell differentiation", "Regulation of t helper 1 type immune response", "Regulation of t helper 2 cell differentiation", "Regulation of t helper cell differentiation", "Regulation of tau protein kinase activity", "Regulation of telomerase activity", "Regulation of telomere capping", "Regulation of telomere maintenance", "Regulation of telomere maintenance via telomere lengthening", "Regulation of tetrapyrrole metabolic process", "Regulation of the force of heart contraction", "Regulation of thymocyte apoptotic process", "Regulation of tissue remodeling", "Regulation of tolerance induction", "Regulation of toll like receptor 2 signaling pathway", "Regulation of toll like receptor 3 signaling pathway", "Regulation of toll like receptor 4 signaling pathway", "Regulation of toll like receptor 7 signaling pathway", "Regulation of toll like receptor 9 signaling pathway", "Regulation of toll like receptor signaling pathway", "Regulation of tooth mineralization", "Regulation of tor signaling", "Regulation of torc2 signaling", "Regulation of trail activated apoptotic signaling pathway", "Regulation of trans synaptic signaling", "Regulation of transcription by glucose", "Regulation of transcription by rna polymerase i", "Regulation of transcription by rna polymerase iii", "Regulation of transcription elongation from rna polymerase ii promoter", "Regulation of transcription from rna polymerase ii promoter in response to hypoxia", "Regulation of transcription from rna polymerase ii promoter in response to oxidative stress", "Regulation of transcription involved in g1 s transition of mitotic cell cycle", "Regulation of transcription of nucleolar large rrna by rna polymerase i", "Regulation of transcription regulatory region dna binding", "Regulation of transferase activity", "Regulation of transforming growth factor beta activation", "Regulation of transforming growth factor beta1 production", "Regulation of translation at synapse modulating synaptic transmission", "Regulation of translation in response to endoplasmic reticulum stress", "Regulation of translation in response to stress", "Regulation of translation initiation in response to endoplasmic reticulum stress", "Regulation of translational elongation", "Regulation of translational fidelity", "Regulation of translational initiation", "Regulation of translational initiation by eif2 alpha phosphorylation", "Regulation of translational initiation in response to stress", "Regulation of translational termination", "Regulation of transmembrane receptor protein serine threonine kinase signaling pathway", "Regulation of transmembrane transport", "Regulation of transmission of nerve impulse", "Regulation of transport", "Regulation of transporter activity", "Regulation of transposition", "Regulation of triglyceride biosynthetic process", "Regulation of triglyceride catabolic process", "Regulation of triglyceride metabolic process", "Regulation of tube size", "Regulation of tumor necrosis factor mediated signaling pathway", "Regulation of type b pancreatic cell development", "Regulation of type b pancreatic cell proliferation", "Regulation of type i interferon mediated signaling pathway", "Regulation of ubiquitin dependent protein catabolic process", "Regulation of ubiquitin protein ligase activity", "Regulation of ubiquitin protein transferase activity", "Regulation of ubiquitin specific protease activity", "Regulation of unsaturated fatty acid biosynthetic process", "Regulation of urine volume", "Regulation of vacuole organization", "Regulation of vascular associated smooth muscle cell differentiation", "Regulation of vascular associated smooth muscle contraction", "Regulation of vascular endothelial growth factor receptor signaling pathway", "Regulation of vascular permeability", "Regulation of vascular wound healing", "Regulation of vasculature development", "Regulation of vasculogenesis", "Regulation of vasoconstriction", "Regulation of ventricular cardiac muscle cell action potential", "Regulation of very low density lipoprotein particle clearance", "Regulation of vesicle fusion", "Regulation of vesicle mediated transport", "Regulation of vesicle size", "Regulation of viral entry into host cell", "Regulation of viral genome replication", "Regulation of viral induced cytoplasmic pattern recognition receptor signaling pathway", "Regulation of viral process", "Regulation of viral transcription", "Regulation of vitamin d receptor signaling pathway", "Regulation of vitamin metabolic process", "Regulation of voltage gated calcium channel activity", "Regulation of water loss via skin", "Regulation of wnt signaling pathway", "Regulation of wound healing", "Regulation of wound healing spreading of epidermal cells", "Regulation of xenophagy", "Relaxation of cardiac muscle", "Relaxation of muscle", "Release of cytochrome c from mitochondria", "Release of sequestered calcium ion into cytosol by endoplasmic reticulum", "Renal absorption", "Renal filtration", "Renal sodium excretion", "Renal sodium ion absorption", "Renal sodium ion transport", "Renal system process", "Renal system vasculature development", "Renal system vasculature morphogenesis", "Renal tubular secretion", "Renal tubule development", "Renal vesicle development", "Renal vesicle formation", "Renal water homeostasis", "Replacement ossification", "Replication born double strand break repair via sister chromatid exchange", "Replication fork processing", "Replication fork protection", "Replicative senescence", "Reproduction", "Reproductive behavior", "Reproductive system development", "Rescue of stalled ribosome", "Resolution of meiotic recombination intermediates", "Resolution of recombination intermediates", "Respiratory burst", "Respiratory burst involved in defense response", "Respiratory burst involved in inflammatory response", "Respiratory chain complex iii assembly", "Respiratory chain complex iv assembly", "Respiratory electron transport chain", "Respiratory gaseous exchange by respiratory system", "Respiratory system development", "Respiratory system process", "Response to abiotic stimulus", "Response to acetylcholine", "Response to acid chemical", "Response to acidic ph", "Response to actinomycin d", "Response to activity", "Response to alcohol", "Response to aldosterone", "Response to alkaloid", "Response to amine", "Response to amino acid starvation", "Response to ammonium ion", "Response to amphetamine", "Response to amyloid beta", "Response to angiotensin", "Response to antibiotic", "Response to arsenic containing substance", "Response to arsenite ion", "Response to atp", "Response to auditory stimulus", "Response to axon injury", "Response to bacterium", "Response to bmp", "Response to cadmium ion", "Response to caffeine", "Response to calcium ion", "Response to camp", "Response to camptothecin", "Response to carbohydrate", "Response to catecholamine", "Response to cell cycle checkpoint signaling", "Response to cgmp", "Response to chemokine", "Response to cholesterol", "Response to cisplatin", "Response to cobalt ion", "Response to cocaine", "Response to cold", "Response to copper ion", "Response to corticosteroid", "Response to corticosterone", "Response to cortisol", "Response to cytokine", "Response to dexamethasone", "Response to dietary excess", "Response to dopamine", "Response to dsrna", "Response to electrical stimulus", "Response to endogenous stimulus", "Response to endoplasmic reticulum stress", "Response to epidermal growth factor", "Response to epinephrine", "Response to estradiol", "Response to estrogen", "Response to ethanol", "Response to ether", "Response to extracellular stimulus", "Response to fatty acid", "Response to fibroblast growth factor", "Response to fluid shear stress", "Response to fluoride", "Response to folic acid", "Response to follicle stimulating hormone", "Response to food", "Response to forskolin", "Response to fungus", "Response to gamma radiation", "Response to glucagon", "Response to glycoprotein", "Response to glycoside", "Response to gonadotropin", "Response to granulocyte macrophage colony stimulating factor", "Response to growth factor", "Response to growth hormone", "Response to heat", "Response to heparin", "Response to hepatocyte growth factor", "Response to histamine", "Response to hormone", "Response to human chorionic gonadotropin", "Response to hydrogen peroxide", "Response to hydroperoxide", "Response to hydrostatic pressure", "Response to hydroxyurea", "Response to hyperoxia", "Response to immobilization stress", "Response to increased oxygen levels", "Response to indole 3 methanol", "Response to inorganic substance", "Response to insecticide", "Response to insulin", "Response to interferon alpha", "Response to interferon beta", "Response to interferon gamma", "Response to interleukin 1", "Response to interleukin 12", "Response to interleukin 17", "Response to interleukin 18", "Response to interleukin 3", "Response to interleukin 4", "Response to interleukin 6", "Response to interleukin 7", "Response to ionizing radiation", "Response to iron ii ion", "Response to iron ion", "Response to ischemia", "Response to isoquinoline alkaloid", "Response to ketone", "Response to l ascorbic acid", "Response to l glutamate", "Response to l phenylalanine derivative", "Response to lead ion", "Response to lectin", "Response to leptin", "Response to leucine", "Response to leukemia inhibitory factor", "Response to light intensity", "Response to light stimulus", "Response to lipid", "Response to lipoteichoic acid", "Response to lithium ion", "Response to magnesium ion", "Response to manganese ion", "Response to mechanical stimulus", "Response to mercury ion", "Response to metal ion", "Response to methylmercury", "Response to mineralocorticoid", "Response to misfolded protein", "Response to mitochondrial depolarisation", "Response to molecule of bacterial origin", "Response to monosaccharide", "Response to muramyl dipeptide", "Response to muscle activity", "Response to muscle stretch", "Response to nerve growth factor", "Response to nicotine", "Response to nitric oxide", "Response to nitrogen compound", "Response to nitrosative stress", "Response to nutrient", "Response to oleic acid", "Response to organic cyclic compound", "Response to osmotic stress", "Response to oxidative stress", "Response to oxygen containing compound", "Response to oxygen glucose deprivation", "Response to oxygen levels", "Response to oxygen radical", "Response to pain", "Response to parathyroid hormone", "Response to peptide", "Response to peptide hormone", "Response to peptidoglycan", "Response to ph", "Response to phorbol 13 acetate 12 myristate", "Response to platelet derived growth factor", "Response to potassium ion", "Response to progesterone", "Response to prostaglandin", "Response to prostaglandin e", "Response to purine containing compound", "Response to radiation", "Response to reactive oxygen species", "Response to redox state", "Response to retinoic acid", "Response to salt", "Response to salt stress", "Response to selenium ion", "Response to sodium arsenite", "Response to sorbitol", "Response to starvation", "Response to steroid hormone", "Response to sterol", "Response to sterol depletion", "Response to temperature stimulus", "Response to testosterone", "Response to thyroglobulin triiodothyronine", "Response to thyroid hormone", "Response to thyroxine", "Response to topologically incorrect protein", "Response to toxic substance", "Response to transforming growth factor beta", "Response to tumor cell", "Response to tumor necrosis factor", "Response to type i interferon", "Response to uv", "Response to uv a", "Response to uv b", "Response to uv c", "Response to virus", "Response to vitamin", "Response to vitamin a", "Response to vitamin d", "Response to vitamin e", "Response to vitamin k", "Response to water", "Response to wounding", "Response to x ray", "Response to xenobiotic stimulus", "Response to yeast", "Response to zinc ion", "Reticulophagy", "Retina development in camera type eye", "Retina homeostasis", "Retina layer formation", "Retina morphogenesis in camera type eye", "Retina vasculature development in camera type eye", "Retina vasculature morphogenesis in camera type eye", "Retinal cell apoptotic process", "Retinal cone cell differentiation", "Retinal ganglion cell axon guidance", "Retinal metabolic process", "Retinal pigment epithelium development", "Retinal rod cell development", "Retinal rod cell differentiation", "Retinoic acid metabolic process", "Retinoic acid receptor signaling pathway", "Retinol metabolic process", "Retrograde axonal transport", "Retrograde trans synaptic signaling", "Retrograde trans synaptic signaling by lipid", "Retrograde transport endosome to golgi", "Retrograde transport vesicle recycling within golgi", "Retrograde vesicle mediated transport golgi to endoplasmic reticulum", "Reverse cholesterol transport", "Reversible differentiation", "Rho protein signal transduction", "Rhodopsin mediated signaling pathway", "Rhythmic behavior", "Rhythmic process", "Riboflavin metabolic process", "Ribonucleoprotein complex biogenesis", "Ribonucleoprotein complex disassembly", "Ribonucleoprotein complex localization", "Ribonucleoprotein complex subunit organization", "Ribonucleoside catabolic process", "Ribonucleoside diphosphate biosynthetic process", "Ribonucleoside diphosphate catabolic process", "Ribonucleoside diphosphate metabolic process", "Ribonucleoside metabolic process", "Ribonucleoside monophosphate biosynthetic process", "Ribonucleoside monophosphate catabolic process", "Ribonucleoside monophosphate metabolic process", "Ribonucleoside triphosphate biosynthetic process", "Ribonucleoside triphosphate metabolic process", "Ribonucleotide catabolic process", "Ribose phosphate biosynthetic process", "Ribose phosphate metabolic process", "Ribosomal large subunit assembly", "Ribosomal large subunit biogenesis", "Ribosomal large subunit export from nucleus", "Ribosomal small subunit assembly", "Ribosomal small subunit biogenesis", "Ribosomal small subunit export from nucleus", "Ribosomal subunit export from nucleus", "Ribosome assembly", "Ribosome associated ubiquitin dependent protein catabolic process", "Ribosome biogenesis", "Ribosome disassembly", "Rig i signaling pathway", "Righting reflex", "Rna 3 end processing", "Rna 3 uridylation", "Rna 5 end processing", "Rna capping", "Rna catabolic process", "Rna decapping", "Rna dependent dna biosynthetic process", "Rna destabilization", "Rna export from nucleus", "Rna guanine n7 methylation", "Rna import into mitochondrion", "Rna interference", "Rna localization", "Rna mediated gene silencing by inhibition of translation", "Rna methylation", "Rna modification", "Rna phosphodiester bond hydrolysis", "Rna phosphodiester bond hydrolysis endonucleolytic", "Rna phosphodiester bond hydrolysis exonucleolytic", "Rna polyadenylation", "Rna polymerase i preinitiation complex assembly", "Rna polymerase ii preinitiation complex assembly", "Rna processing", "Rna secondary structure unwinding", "Rna splicing", "Rna splicing via endonucleolytic cleavage and ligation", "Rna splicing via transesterification reactions", "Rna stabilization", "Rna surveillance", "Roof of mouth development", "Rostrocaudal neural tube patterning", "Roundabout signaling pathway", "Rrna 3 end processing", "Rrna 5 end processing", "Rrna base methylation", "Rrna catabolic process", "Rrna metabolic process", "Rrna methylation", "Rrna modification", "Rrna pseudouridine synthesis", "Rrna transcription", "Rrna transport", "Ruffle assembly", "Ruffle organization", "S adenosylmethionine cycle", "S adenosylmethionine metabolic process", "Salivary gland development", "Sarcomere organization", "Sarcoplasmic reticulum calcium ion transport", "Satellite cell activation involved in skeletal muscle regeneration", "Scarna localization to cajal body", "Scf dependent proteasomal ubiquitin dependent protein catabolic process", "Schwann cell development", "Schwann cell differentiation", "Schwann cell proliferation", "Second messenger mediated signaling", "Secondary alcohol metabolic process", "Secondary metabolic process", "Secondary metabolite biosynthetic process", "Secondary palate development", "Secretion", "Secretion by tissue", "Secretion of lysosomal enzymes", "Secretory granule localization", "Secretory granule organization", "Segment specification", "Segmentation", "Selective autophagy", "Self proteolysis", "Semaphorin plexin signaling pathway", "Semaphorin plexin signaling pathway involved in neuron projection guidance", "Semi lunar valve development", "Semicircular canal development", "Semicircular canal morphogenesis", "Seminiferous tubule development", "Sensory organ development", "Sensory organ morphogenesis", "Sensory perception", "Sensory perception of bitter taste", "Sensory perception of chemical stimulus", "Sensory perception of light stimulus", "Sensory perception of mechanical stimulus", "Sensory perception of pain", "Sensory perception of smell", "Sensory perception of sweet taste", "Sensory perception of taste", "Sensory perception of temperature stimulus", "Sensory system development", "Septum primum development", "Sequestering of actin monomers", "Sequestering of calcium ion", "Sequestering of iron ion", "Sequestering of metal ion", "Sequestering of triglyceride", "Sequestering of zinc ion", "Serine family amino acid biosynthetic process", "Serine family amino acid catabolic process", "Serine family amino acid metabolic process", "Serine phosphorylation of stat protein", "Serine transport", "Serotonin metabolic process", "Sertoli cell development", "Sertoli cell differentiation", "Sex determination", "Sex differentiation", "Short chain fatty acid catabolic process", "Short chain fatty acid metabolic process", "Short term memory", "Signal complex assembly", "Signal peptide processing", "Signal release", "Signal transduction by p53 class mediator", "Signal transduction in absence of ligand", "Signal transduction in response to dna damage", "Signal transduction involved in regulation of gene expression", "Signaling receptor ligand precursor processing", "Single fertilization", "Single strand break repair", "Single stranded viral rna replication via double stranded dna intermediate", "Sister chromatid cohesion", "Sister chromatid segregation", "Skeletal muscle acetylcholine gated channel clustering", "Skeletal muscle adaptation", "Skeletal muscle cell differentiation", "Skeletal muscle cell proliferation", "Skeletal muscle contraction", "Skeletal muscle fiber differentiation", "Skeletal muscle organ development", "Skeletal muscle satellite cell activation", "Skeletal muscle tissue regeneration", "Skeletal myofibril assembly", "Skeletal system development", "Skeletal system morphogenesis", "Skin development", "Skin epidermis development", "Skin morphogenesis", "Sleep", "Smad protein complex assembly", "Smad protein signal transduction", "Small gtpase mediated signal transduction", "Small molecule biosynthetic process", "Small molecule catabolic process", "Small molecule metabolic process", "Small nucleolar ribonucleoprotein complex assembly", "Small rna loading onto risc", "Smooth muscle adaptation", "Smooth muscle cell apoptotic process", "Smooth muscle cell chemotaxis", "Smooth muscle cell differentiation", "Smooth muscle cell migration", "Smooth muscle cell proliferation", "Smooth muscle contraction", "Smooth muscle tissue development", "Smoothened signaling pathway", "Smoothened signaling pathway involved in dorsal ventral neural tube patterning", "Snare complex assembly", "Sno s rna metabolic process", "Sno s rna processing", "Snorna localization", "Snrna metabolic process", "Snrna modification", "Snrna processing", "Snrna transcription", "Snrna transcription by rna polymerase ii", "Snrna transport", "Sodium independent organic anion transport", "Sodium ion export across plasma membrane", "Sodium ion homeostasis", "Sodium ion import across plasma membrane", "Sodium ion transmembrane transport", "Sodium ion transport", "Somatic diversification of immune receptors", "Somatic diversification of immune receptors via somatic mutation", "Somatic diversification of immunoglobulins", "Somatic diversification of immunoglobulins involved in immune response", "Somatic diversification of t cell receptor genes", "Somatic stem cell population maintenance", "Somite development", "Somite rostral caudal axis specification", "Somitogenesis", "Specification of animal organ identity", "Specification of symmetry", "Sperm capacitation", "Sperm dna condensation", "Sperm egg recognition", "Sperm flagellum assembly", "Sperm motility", "Spermatid differentiation", "Spermatid nucleus differentiation", "Spermatogenesis exchange of chromosomal proteins", "Spermidine metabolic process", "Spermine metabolic process", "Sphingoid metabolic process", "Sphingolipid biosynthetic process", "Sphingolipid mediated signaling pathway", "Sphingolipid metabolic process", "Sphingolipid translocation", "Sphingomyelin biosynthetic process", "Sphingomyelin catabolic process", "Sphingomyelin metabolic process", "Sphingosine biosynthetic process", "Spinal cord development", "Spinal cord motor neuron differentiation", "Spindle assembly", "Spindle assembly involved in female meiosis", "Spindle elongation", "Spindle localization", "Spindle midzone assembly", "Spindle organization", "Spleen development", "Spliceosomal complex assembly", "Spliceosomal conformational changes to generate catalytic conformation", "Spliceosomal snrnp assembly", "Spliceosomal tri snrnp complex assembly", "Spontaneous synaptic transmission", "Sprouting angiogenesis", "Srp dependent cotranslational protein targeting to membrane", "Srp dependent cotranslational protein targeting to membrane signal sequence recognition", "Srp dependent cotranslational protein targeting to membrane translocation", "Startle response", "Stem cell differentiation", "Stem cell division", "Stem cell proliferation", "Steroid biosynthetic process", "Steroid catabolic process", "Steroid esterification", "Steroid hormone biosynthetic process", "Steroid hormone mediated signaling pathway", "Steroid hormone secretion", "Steroid metabolic process", "Sterol biosynthetic process", "Sterol homeostasis", "Sterol import", "Sterol metabolic process", "Sterol transport", "Strand invasion", "Stress activated protein kinase signaling cascade", "Stress fiber assembly", "Stress granule assembly", "Stress granule disassembly", "Stress induced premature senescence", "Stress response to metal ion", "Striated muscle adaptation", "Striated muscle cell apoptotic process", "Striated muscle cell development", "Striated muscle cell differentiation", "Striated muscle cell proliferation", "Striated muscle contraction", "Striatum development", "Subpallium development", "Substantia nigra development", "Substrate adhesion dependent cell spreading", "Substrate dependent cell migration", "Substrate dependent cell migration cell extension", "Substrate independent telencephalic tangential migration", "Subtelomeric heterochromatin assembly", "Succinate metabolic process", "Succinate transmembrane transport", "Succinyl coa metabolic process", "Suckling behavior", "Sugar mediated signaling pathway", "Sulfate transport", "Sulfation", "Sulfur amino acid biosynthetic process", "Sulfur amino acid catabolic process", "Sulfur amino acid metabolic process", "Sulfur compound biosynthetic process", "Sulfur compound catabolic process", "Sulfur compound metabolic process", "Sulfur compound transport", "Superoxide anion generation", "Superoxide metabolic process", "Suppression of viral release by host", "Supramolecular fiber organization", "Sympathetic ganglion development", "Sympathetic nervous system development", "Synapse assembly", "Synapse maturation", "Synapse organization", "Synapse pruning", "Synaptic assembly at neuromuscular junction", "Synaptic membrane adhesion", "Synaptic signaling", "Synaptic transmission dopaminergic", "Synaptic transmission gabaergic", "Synaptic transmission glutamatergic", "Synaptic vesicle budding", "Synaptic vesicle clustering", "Synaptic vesicle cytoskeletal transport", "Synaptic vesicle docking", "Synaptic vesicle endosomal processing", "Synaptic vesicle exocytosis", "Synaptic vesicle localization", "Synaptic vesicle maturation", "Synaptic vesicle membrane organization", "Synaptic vesicle priming", "Synaptic vesicle recycling", "Synaptic vesicle recycling via endosome", "Synaptic vesicle transport", "Synaptic vesicle uncoating", "Synaptonemal complex organization", "Syncytium formation", "T cell activation", "T cell activation involved in immune response", "T cell activation via t cell receptor contact with antigen bound to mhc molecule on antigen presenting cell", "T cell apoptotic process", "T cell chemotaxis", "T cell cytokine production", "T cell differentiation", "T cell differentiation in thymus", "T cell differentiation involved in immune response", "T cell extravasation", "T cell homeostasis", "T cell lineage commitment", "T cell mediated cytotoxicity", "T cell mediated immune response to tumor cell", "T cell mediated immunity", "T cell migration", "T cell proliferation", "T cell proliferation involved in immune response", "T cell receptor signaling pathway", "T cell selection", "T cell tolerance induction", "T helper 1 cell differentiation", "T helper 1 type immune response", "T helper 17 cell differentiation", "T helper 17 cell lineage commitment", "T helper 17 type immune response", "T helper 2 cell differentiation", "T helper cell lineage commitment", "T tubule organization", "Tail anchored membrane protein insertion into er membrane", "Tangential migration from the subventricular zone to the olfactory bulb", "Taurine transport", "Taxis", "Telencephalon development", "Telencephalon glial cell migration", "Telencephalon regionalization", "Telomerase holoenzyme complex assembly", "Telomerase rna localization", "Telomere capping", "Telomere maintenance", "Telomere maintenance in response to dna damage", "Telomere maintenance via recombination", "Telomere maintenance via semi conservative replication", "Telomere maintenance via telomere lengthening", "Telomere organization", "Telomeric d loop disassembly", "Telomeric loop disassembly", "Temperature homeostasis", "Terminal button organization", "Termination of rna polymerase ii transcription", "Terpenoid biosynthetic process", "Terpenoid metabolic process", "Tertiary alcohol metabolic process", "Tetrahydrobiopterin metabolic process", "Tetrahydrofolate biosynthetic process", "Tetrahydrofolate interconversion", "Tetrahydrofolate metabolic process", "Tetrapyrrole biosynthetic process", "Tetrapyrrole catabolic process", "Tetrapyrrole metabolic process", "Thalamus development", "Thiamine containing compound metabolic process", "Thiamine transport", "Thioester biosynthetic process", "Thioester metabolic process", "Thorax and anterior abdomen determination", "Threonine catabolic process", "Threonine metabolic process", "Thrombin activated receptor signaling pathway", "Thrombopoietin mediated signaling pathway", "Thymic t cell selection", "Thymocyte apoptotic process", "Thymus development", "Thyroid gland development", "Thyroid hormone generation", "Thyroid hormone mediated signaling pathway", "Thyroid hormone metabolic process", "Thyroid hormone transport", "Tight junction organization", "Tissue development", "Tissue migration", "Tissue morphogenesis", "Tissue regeneration", "Tissue remodeling", "Tolerance induction", "Toll like receptor 2 signaling pathway", "Toll like receptor 3 signaling pathway", "Toll like receptor 4 signaling pathway", "Toll like receptor 7 signaling pathway", "Toll like receptor 8 signaling pathway", "Toll like receptor 9 signaling pathway", "Toll like receptor signaling pathway", "Tongue development", "Tongue morphogenesis", "Tooth mineralization", "Tor signaling", "Torc1 signaling", "Torc2 signaling", "Toxin metabolic process", "Toxin transport", "Trabecula formation", "Trabecula morphogenesis", "Trachea development", "Trachea formation", "Trachea morphogenesis", "Trail activated apoptotic signaling pathway", "Trans synaptic signaling by lipid", "Trans synaptic signaling by trans synaptic complex", "Trans synaptic signaling modulating synaptic transmission", "Transcription by rna polymerase i", "Transcription by rna polymerase iii", "Transcription coupled nucleotide excision repair", "Transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery", "Transcription elongation from rna polymerase i promoter", "Transcription elongation from rna polymerase ii promoter", "Transcription initiation from rna polymerase i promoter", "Transcription initiation from rna polymerase ii promoter", "Transcription initiation from rna polymerase iii promoter", "Transcription preinitiation complex assembly", "Transcytosis", "Transdifferentiation", "Transepithelial chloride transport", "Transepithelial transport", "Transferrin transport", "Transforming growth factor beta activation", "Transforming growth factor beta production", "Transforming growth factor beta receptor signaling pathway", "Transforming growth factor beta1 production", "Transition between fast and slow fiber", "Transition metal ion homeostasis", "Transition metal ion transport", "Translational elongation", "Translational initiation", "Translational readthrough", "Translational termination", "Translesion synthesis", "Translocation of molecules into host", "Transmembrane receptor protein serine threonine kinase signaling pathway", "Transmembrane receptor protein tyrosine kinase signaling pathway", "Transmembrane receptor protein tyrosine phosphatase signaling pathway", "Transmembrane transport", "Transmission of nerve impulse", "Transport along microtubule", "Transport of virus", "Transposition", "Transposition rna mediated", "Tricarboxylic acid cycle", "Tricarboxylic acid metabolic process", "Trigeminal ganglion development", "Trigeminal nerve development", "Trigeminal nerve morphogenesis", "Triglyceride biosynthetic process", "Triglyceride catabolic process", "Triglyceride metabolic process", "Triglyceride rich lipoprotein particle clearance", "Tripartite regional subdivision", "Tripeptide transmembrane transport", "Tripeptide transport", "Trivalent inorganic anion homeostasis", "Trna 3 end processing", "Trna 5 end processing", "Trna 5 leader removal", "Trna aminoacylation for mitochondrial protein translation", "Trna catabolic process", "Trna metabolic process", "Trna methylation", "Trna modification", "Trna processing", "Trna pseudouridine synthesis", "Trna thio modification", "Trna threonylcarbamoyladenosine metabolic process", "Trna transcription", "Trna transport", "Trna wobble base modification", "Trna wobble uridine modification", "Trophectodermal cell differentiation", "Trophoblast cell migration", "Trophoblast giant cell differentiation", "Tryptophan transport", "Tube development", "Tube formation", "Tube morphogenesis", "Tubulin complex assembly", "Tubulin deacetylation", "Tumor necrosis factor mediated signaling pathway", "Tumor necrosis factor superfamily cytokine production", "Type 2 immune response", "Type b pancreatic cell apoptotic process", "Type b pancreatic cell development", "Type b pancreatic cell proliferation", "Type i interferon production", "Type i pneumocyte differentiation", "Tyrosine catabolic process", "Tyrosine metabolic process", "Tyrosine phosphorylation of stat protein", "U4 snrna 3 end processing", "Ubiquinone metabolic process", "Ubiquitin dependent endocytosis", "Ubiquitin dependent erad pathway", "Ubiquitin dependent glycoprotein erad pathway", "Ubiquitin dependent protein catabolic process via the c end degron rule pathway", "Ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin dependent smad protein catabolic process", "Ubiquitin independent protein catabolic process via the multivesicular body sorting pathway", "Ubiquitin recycling", "Udp glucose metabolic process", "Udp n acetylglucosamine biosynthetic process", "Udp n acetylglucosamine metabolic process", "Ump biosynthetic process", "Unsaturated fatty acid biosynthetic process", "Unsaturated fatty acid metabolic process", "Urate metabolic process", "Urate transport", "Urea cycle", "Urea metabolic process", "Ureter development", "Ureter morphogenesis", "Ureteric bud elongation", "Urinary bladder smooth muscle contraction", "Urinary tract smooth muscle contraction", "Urogenital system development", "Uronic acid metabolic process", "Uterine smooth muscle contraction", "Uterus development", "Uterus morphogenesis", "Utp biosynthetic process", "Utp metabolic process", "Uv damage excision repair", "Uv protection", "V d j recombination", "Vacuolar acidification", "Vacuolar localization", "Vacuolar proton transporting v type atpase complex assembly", "Vacuolar transport", "Vacuole organization", "Vagina development", "Valine metabolic process", "Vascular associated smooth muscle cell apoptotic process", "Vascular associated smooth muscle cell differentiation", "Vascular associated smooth muscle cell migration", "Vascular associated smooth muscle cell proliferation", "Vascular associated smooth muscle contraction", "Vascular endothelial cell proliferation", "Vascular endothelial growth factor production", "Vascular endothelial growth factor receptor 2 signaling pathway", "Vascular endothelial growth factor receptor signaling pathway", "Vascular endothelial growth factor signaling pathway", "Vascular process in circulatory system", "Vascular transport", "Vascular wound healing", "Vasculature development", "Vasculogenesis", "Vasoconstriction", "Vasodilation", "Ventral spinal cord development", "Ventricular cardiac muscle cell action potential", "Ventricular cardiac muscle cell development", "Ventricular cardiac muscle cell differentiation", "Ventricular cardiac muscle cell membrane repolarization", "Ventricular cardiac muscle tissue development", "Ventricular cardiac muscle tissue morphogenesis", "Ventricular compact myocardium morphogenesis", "Ventricular septum development", "Ventricular septum morphogenesis", "Ventricular system development", "Ventricular trabecula myocardium morphogenesis", "Very long chain fatty acid catabolic process", "Very long chain fatty acid metabolic process", "Very low density lipoprotein particle assembly", "Very low density lipoprotein particle clearance", "Vesicle budding from membrane", "Vesicle cargo loading", "Vesicle cytoskeletal trafficking", "Vesicle docking", "Vesicle docking involved in exocytosis", "Vesicle fusion to plasma membrane", "Vesicle fusion with golgi apparatus", "Vesicle localization", "Vesicle mediated cholesterol transport", "Vesicle mediated transport", "Vesicle mediated transport between endosomal compartments", "Vesicle mediated transport in synapse", "Vesicle mediated transport to the plasma membrane", "Vesicle organization", "Vesicle targeting", "Vesicle targeting rough er to cis golgi", "Vesicle targeting to from or within golgi", "Vesicle tethering", "Vesicle tethering to golgi", "Vesicle transport along microtubule", "Vesicle uncoating", "Vestibulocochlear nerve development", "Vestibulocochlear nerve morphogenesis", "Viral budding", "Viral gene expression", "Viral genome replication", "Viral life cycle", "Viral process", "Viral protein processing", "Viral release from host cell", "Viral rna genome replication", "Viral transcription", "Viral translation", "Viral translational termination reinitiation", "Virion assembly", "Virion attachment to host cell", "Visual behavior", "Vitamin a metabolic process", "Vitamin b6 metabolic process", "Vitamin biosynthetic process", "Vitamin catabolic process", "Vitamin d metabolic process", "Vitamin d receptor signaling pathway", "Vitamin k metabolic process", "Vitamin metabolic process", "Vitamin transmembrane transport", "Vitamin transport", "Vocalization behavior", "Voluntary musculoskeletal movement", "Walking behavior", "Water homeostasis", "Water soluble vitamin biosynthetic process", "Water soluble vitamin metabolic process", "Water transport", "White fat cell differentiation", "Wnt protein secretion", "Wnt signaling pathway involved in heart development", "Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation", "Wound healing", "Wound healing involved in inflammatory response", "Wound healing spreading of epidermal cells", "Xenobiotic catabolic process", "Xenobiotic export", "Xenobiotic metabolic process", "Xenobiotic transmembrane transport", "Xenobiotic transport", "Xenobiotic transport across blood brain barrier", "Xenophagy", "Xmp metabolic process", "Zinc ion homeostasis", "Zinc ion import across plasma membrane", "Zinc ion transport", "Zygotic determination of anterior posterior axis embryo", "Zymogen activation", "Zymogen inhibition"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF3", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "ALYREF", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APOBEC3C", "APOC1", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL8B", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf76", "C12orf43", "C12orf57", "C12orf73", "C17orf75", "C19orf70", "C1QBP", "C2CD2L", "C2CD5", "C2orf49", "C3orf33", "C3orf58", "C5orf51", "C9orf64", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC134", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC93", "CCDC94", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPH", "CENPK", "CENPP", "CENPU", "CENPV", "CEP131", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD6", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM129B", "FAM162A", "FAM173A", "FAM207A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FN3KRP", "FNBP1", "FNDC3A", "FNTA", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC1", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHITM", "GID4", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRS4", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCOS", "MOCS1", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL19", "MRPL2", "MRPL20", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS24", "MRPS27", "MRPS28", "MRPS30", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS6", "MRPS7", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTF2", "MTFP1", "MTFR1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKBIL1", "NFS1", "NFU1", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAWR", "PAX6", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD11", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PET100", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2D", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL3", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM39", "RBM4", "RBM42", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCOC", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLAIN2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TCTN3", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THADA", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM161A", "TMEM165", "TMEM167A", "TMEM199", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1AIP2", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC37", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBL5", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMA21", "VMP1", "VPS13A", "VPS13D", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WRAP73", "WRN", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YIF1B", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZDHHC13", "ZFPL1", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["AARS2", "AASDHPPT", "ABAT", "ABCB7", "ABCC4", "ABCD4", "ABI1", "ACADVL", "ACAT2", "ACBD3", "ACOX3", "ACP2", "ACP6", "ACSL3", "ACSL6", "ACTN1", "ACTN4", "ACTR2", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADK", "ADNP", "AFG3L2", "AGPS", "AHCYL1", "AIFM1", "AKAP12", "AKT1", "AKT2", "ALCAM", "ALDH1A2", "ALDH1B1", "AMOT", "AMPD2", "ANAPC7", "ANK3", "ANKLE2", "ANXA1", "AP2M1", "APBB1", "APLP2", "APP", "ARHGAP1", "ARHGAP10", "ARHGEF1", "ARID2", "ARIH1", "ARL6IP1", "ARMC10", "ARVCF", "ASNA1", "ASPH", "ATL3", "ATP13A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5L", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "AUP1", "AURKA", "AURKB", "B3GALT6", "B4GALT1", "B4GALT3", "B4GAT1", "BAG6", "BAIAP2", "BAZ1B", "BAZ2A", "BBS4", "BCAS3", "BCL2L13", "BCLAF1", "BCR", "BECN1", "BICD2", "BRD4", "BSG", "BUB1B", "C12orf73", "C1QBP", "C2CD2L", "C3orf58", "CADM1", "CALCOCO1", "CAMK1", "CAMK2G", "CANT1", "CAPN2", "CAPN5", "CARM1", "CASK", "CCDC22", "CCDC93", "CCT2", "CD2AP", "CD2BP2", "CD320", "CDC20", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC7", "CDH2", "CDK1", "CDK16", "CDK2", "CDK4", "CDK5RAP3", "CDK6", "CENPH", "CENPK", "CEP131", "CEP250", "CEP290", "CEPT1", "CERS1", "CERS2", "CFDP1", "CHAF1B", "CHAMP1", "CHCHD3", "CHD7", "CHERP", "CHKA", "CHMP1A", "CHMP5", "CHORDC1", "CHST14", "CHUK", "CISD1", "CLASP1", "CLCN3", "CLCN7", "CLN5", "CLN6", "CLPP", "CLSTN3", "CLTC", "CLU", "CLUH", "CNNM4", "CNOT11", "CNOT3", "COA3", "COG3", "COLEC12", "COPB2", "COPG1", "COPS2", "COPS3", "COPS4", "COPS7A", "COPS7B", "CORO1B", "COX15", "COX2", "COX5A", "CPD", "CPSF3", "CPSF7", "CPT2", "CPVL", "CRTAP", "CSNK1A1", "CSNK2B", "CSRP2", "CSTF1", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTR9", "CTSA", "CXorf57", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DCP1B", "DCTN1", "DCTN3", "DCTPP1", "DCUN1D4", "DDRGK1", "DDX17", "DDX20", "DDX3X", "DDX5", "DDX56", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHX36", "DHX37", "DIABLO", "DICER1", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC7", "DOCK1", "DOCK7", "DSG2", "DVL2", "DYM", "DYNC2H1", "EARS2", "ECE1", "EEA1", "EED", "EEF1A2", "EEF1E1", "EHD4", "EIF2AK2", "EIF2B2", "EIF3E", "EIF3F", "EIF4H", "EIF5", "EIF5A", "ELMO2", "EMD", "EML4", "ENDOG", "EPB41L2", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPS15", "ERAP1", "ERBIN", "ERC1", "ERGIC3", "EXO1", "EXOC2", "EXOC7", "EXOSC2", "EXOSC3", "EZH2", "EZR", "FAH", "FAM129B", "FAM162A", "FAM49B", "FAM98A", "FANCG", "FASN", "FECH", "FERMT2", "FGFR1OP", "FHL1", "FIS1", "FKBP8", "FKRP", "FLAD1", "FLII", "FLOT1", "FMR1", "FNBP1", "FNTA", "FOXRED1", "FRG1", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GAK", "GAL", "GALNT1", "GARS", "GBA", "GBF1", "GCC2", "GHITM", "GID4", "GINS4", "GLA", "GLB1", "GLG1", "GLMN", "GNA13", "GNAI2", "GNAI3", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA5", "GOLM1", "GPAM", "GPATCH4", "GPR107", "GPR108", "GSK3A", "GSK3B", "GSR", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP4", "GUSB", "H2AFY", "H2AFY2", "HACD2", "HAUS1", "HAUS4", "HAUS5", "HDAC1", "HDAC2", "HDGFL2", "HDHD5", "HEBP2", "HELLS", "HERC2", "HEXIM1", "HIP1", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HMCES", "HMGB1", "HMGB2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPU", "HOOK1", "HOOK2", "HOOK3", "HPS6", "HS1BP3", "HSD17B12", "HSD17B7", "HSP90AB1", "ICMT", "IDH2", "IFIT5", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2R", "IK", "IKBIP", "ILK", "IMMT", "IMPACT", "IMPAD1", "INA", "INPP4A", "IPO5", "IQCB1", "IQGAP1", "IQGAP3", "ISOC2", "ISY1", "ITGA2", "ITGAV", "ITM2C", "ITSN2", "IWS1", "JAM3", "KARS", "KCTD21", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KHDRBS1", "KHSRP", "KIF11", "KIF22", "KIF23", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KLC1", "KNSTRN", "KNTC1", "KPNA2", "KPNA6", "KTN1", "LAMB1", "LAMP1", "LANCL2", "LARS", "LBR", "LEMD3", "LGALS3", "LGALS3BP", "LGMN", "LIG3", "LIMA1", "LIN28B", "LLGL1", "LMBRD1", "LMNA", "LMNB1", "LNPEP", "LPGAT1", "LRBA", "LRPAP1", "LRWD1", "LTV1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAN1A2", "MAPK14", "MAPRE1", "MAPRE2", "MARS", "MATR3", "MAVS", "MBOAT7", "MCL1", "MCM2", "MCM6", "MCM7", "MCUB", "MED1", "MED25", "MEPCE", "MFF", "MFN2", "MFSD10", "MFSD8", "MGEA5", "MGST2", "MGST3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MMGT1", "MORF4L1", "MOSPD2", "MOV10", "MPC2", "MPG", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPV17", "MPV17L2", "MRPS11", "MRPS15", "MRPS16", "MRPS24", "MSH2", "MSH3", "MSN", "MTA1", "MTAP", "MTBP", "MTCH2", "MTF2", "MTG1", "MTIF2", "MTOR", "MTR", "MTX1", "MTX2", "MYCBP2", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "NAA16", "NAGK", "NAGLU", "NAMPT", "NAP1L1", "NAPG", "NASP", "NAT10", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCAPH", "NCDN", "NCEH1", "NCL", "NCSTN", "ND1", "NDC1", "NDE1", "NDUFAF7", "NDUFB3", "NDUFS2", "NDUFS6", "NDUFS7", "NEFL", "NELFB", "NELFCD", "NENF", "NES", "NIFK", "NLN", "NMD3", "NNT", "NOC2L", "NOL11", "NOL8", "NONO", "NOP53", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NRDE2", "NRP1", "NSD1", "NSD2", "NSD3", "NSL1", "NSUN2", "NSUN5", "NUBP2", "NUCB1", "NUCB2", "NUDT16L1", "NUMA1", "NUP107", "NUP205", "NUP54", "NUP62", "NUP88", "NUP93", "OBSL1", "OCIAD1", "OCLN", "OGDH", "OPA1", "OSBP", "OSBPL2", "OSBPL3", "OSBPL8", "OXA1L", "OXSR1", "PAF1", "PAFAH1B3", "PAIP2", "PAK1IP1", "PALLD", "PANK4", "PARL", "PARN", 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0.2920427045833941 0.0601280036720452 0.030310154350261 0.0016228568987675 0.0029864990196935 +Vacuole 68 249 2.942145542536579 0.0032594669530479 55.029126213592235 212.35679611650485 0.7895788564169173 0.4204713883128338 16.092847298969616 21.031446114270427 2.221429361906059 0.4148180554719883 0.121447226297853 0.0011253478054363 5.588051306316121e-08 3.0941569176699544e-12 1.972534158656665e-12 +Endocytic vesicle 29 100 2.909599355901146 0.003618923390956 19.521844660194176 83.27669902912622 0.428513908443532 0.5353120905813061 7.647069906220736 7.607555057832984 1.324058617895936 0.3761698531660883 0.1994274007609256 0.0152406110107504 0.003253953987006 0.0004188057435368 5.253530868517565e-05 +Azurophil granule 20 75 2.7903332628121253 0.0052653812859619 20.46359223300971 67.00485436893204 0.4795255752980384 0.3097891700346699 6.177875864944045 5.290582926033595 2.1760997104513735 0.3628132485163926 0.1173573190167662 0.4205819691215787 0.0964752293748221 3.7577030372156096e-06 1.2957940065011837e-07 +Secretory granule membrane 14 75 2.739837246021364 0.0061469615209248 19.699029126213592 69.8495145631068 0.9295860214656708 0.3887665887416008 7.284889203542463 7.49087955205396 1.5950364553562375 0.3903287060113383 0.1789113924942814 0.0531834981275408 0.0290058984012129 0.0014438754065065 0.007033229452604 +Apical plasma membrane 15 54 2.725438442836169 0.0064216149623532 13.313106796116504 44.91504854368932 0.8056122914935105 0.4638533528605782 6.08368206230376 5.803837594461636 1.1490032654706197 0.3657186109722784 1.0 0.5282902438950146 0.017264423515065 0.0878915511914753 0.021751377567624 +Azurophil granule membrane 7 25 2.5723453441188138 0.0101012075552375 7.856796116504855 21.259708737864077 1.0757479237162697 0.2373572682944545 3.393508570011604 2.63895903142419 1.639408148995933 0.2881313440808664 0.048546111259079 0.1955113655682517 0.0707844675435839 0.0007742112182462 0.0003118568141161 +Presynaptic active zone 4 18 2.556398148381084 0.010576202794662 4.803398058252427 14.970873786407768 0.3940654670567658 0.5114928405011878 2.7795522630987173 1.9568466345271975 0.9528581059832693 0.3105803383532612 1.0 0.0221752921749746 0.0112094197528849 0.1140816659952819 0.0882967899938231 +Endocytic vesicle membrane 13 50 2.533420913463988 0.0112955226160549 11.41019417475728 40.75728155339806 0.6528171904926832 0.3529092384633215 4.825015011915381 4.780047567333447 1.5638167276319088 0.3380752375601685 0.1154282376305415 0.0019119564763683 0.0043906698259083 0.0016135045777137 0.0011293778732294 +Proteasome core complex beta subunit complex 5 7 2.5268994704617342 0.011507443681116 3.699029126213592 6.970873786407767 1.6670727234653664 0.1509307531330224 1.4503762582219135 0.1681602725795027 0.9611878160538336 0.233503072382129 1.0 0.04159641685533 0.003087611696091 1.4679347449836997e-08 9.533521740063692e-07 +Endoplasmic reticulum lumen 16 69 2.509169332378961 0.0121015457632569 18.07766990291262 59.737864077669904 0.9896277047863468 0.3946249358858228 7.513340007333169 6.273245958458151 1.4320597420402308 0.3846324865730224 1.0 0.1888134882908049 0.0773417399974191 0.0002227949702616 0.0005537863167585 +Vesicle lumen 29 131 2.5088092385598992 0.0121138883999325 28.93446601941747 119.79368932038837 -0.0708316930912348 0.5682496130595786 13.122391611595372 7.240907185867801 1.2978103845669404 0.3622974798457447 1.0 0.2442032325569902 0.0425635935154873 0.0001038685516711 3.495720390974262e-08 +Proteasome core complex 6 15 2.469557821552609 0.0135280153970891 5.325242718446602 14.563106796116504 1.2215341624098188 0.3078540255827756 2.4387733048296822 0.5516067072365743 1.1166106206832802 0.3218631020970666 1.0 0.0771453392642774 0.0111011801010317 1.837861939916845e-06 7.850220860580527e-06 +Postsynaptic density membrane 4 9 2.385347742874558 0.0170629838685851 1.8106796116504855 6.669902912621359 0.9700827983290172 0.2992953748741365 1.3610684424812354 1.822930264123012 0.935271302642404 0.2569047527325972 0.0371363420154888 0.1524760813950871 0.284754537798848 0.051542815486873 0.0259406914165302 +Intrinsic component of organelle membrane 55 149 2.380306804021398 0.0172982290550285 52.51699029126213 129.34223300970874 2.0732064315361294 0.2796588394070637 24.692225942786415 15.820346456508432 2.8130846896968285 0.39829365000917 1.0 0.4164914742341055 0.5495386138018902 0.0025747616607714 9.80309346527248e-06 +Apical part of cell 17 70 2.364597730278956 0.0180496643677661 15.599514563106796 57.72330097087379 0.5629683512109013 0.5412025823450395 6.485031290002554 7.326381428218615 1.086566128273008 0.3654459232984969 1.0 0.2389579237234044 0.0113965143675507 0.1064919015376139 0.0590356225642136 +Nuclear inner membrane 6 24 2.3250748499479297 0.0200679581992928 7.347087378640777 20.57281553398058 1.3204335588742686 0.2519451141048848 3.6006224195129035 1.9968516080603145 1.2188770932171689 0.2896682474252494 0.0444114041010999 0.1801156574188796 0.3312162786192844 0.0801176308941427 0.0037872519575486 +External side of plasma membrane 12 27 2.281681984814331 0.0225081224375096 6.856796116504855 22.03640776699029 0.7617836494895279 0.3205100812766187 3.0547396608098576 3.343757364022431 1.3549821177336052 0.303342613906597 1.0 0.395163544863046 0.0182837986425535 0.0140990291270638 0.0052663096744702 +Neuromuscular junction 6 20 2.240742331075132 0.025042770394114 4.62621359223301 16.633495145631066 0.4855035135155566 0.54061233402628 2.386469186408936 2.9236472131013795 0.8090611388618595 0.3124321260069755 1.0 0.0173338143393145 0.0628860756551618 0.0035757213036434 0.0009526402681126 +Clathrin coated vesicle 12 55 2.210708589083223 0.0270560233692866 9.936893203883496 47.157766990291265 0.2628715125167937 0.534532305855711 4.553447222704333 4.879804116719352 1.1779559306555245 0.358217133589648 1.0 0.1123544518992548 0.1101605797563029 0.0093103873816233 0.0062896817268026 +Ciliary transition zone 6 11 2.2091341870408603 0.0271653088558785 1.9635922330097089 6.907766990291262 0.9295898692526422 0.3532985326295446 1.5457849700174688 1.7711928579014855 0.854807445224746 0.2896111184937897 1.0 0.2180755491779121 0.3924527927004838 0.1300529274831162 0.039409055534926 +Early endosome 35 118 2.197369554975111 0.02799406379251 24.66504854368932 96.93203883495146 0.530758374709677 0.5743319290889299 8.086272783051246 14.025470683081796 1.1449007118883376 0.3721207721610414 1.0 0.0430687544980389 0.0519285089308565 0.0191971483147747 0.0001086526291756 +Basal part of cell 17 61 2.184375795581073 0.028934645304715 12.87378640776699 49.39563106796116 0.4231791430151931 0.5418083225496748 6.317535484281435 5.887808725837185 1.1575518486276402 0.3620095959132046 0.141150278956068 0.1406119648803149 0.0443229560217491 0.0200202272568271 0.0001460167627222 +Perinuclear region of cytoplasm 45 211 2.1761368003367942 0.0295450329139548 41.351941747572816 185.873786407767 0.188099869779145 0.7574745839917925 13.945452720131469 19.27429981182019 0.8259268596181808 0.3356085544002479 0.4263015546068401 0.0085734718219979 0.0079652520883587 0.0049106468550961 0.0003871972778455 +Platelet alpha granule 5 20 2.148626445055186 0.0316640236433707 4.211165048543689 15.902912621359222 0.6039612674990132 0.4510107266729922 2.510477385063311 2.1030009215071965 0.8798256715017497 0.2887985186703408 1.0 0.0165768393094286 0.0603249601752956 0.0801176308941427 0.0037872519575486 +Golgi lumen 4 6 2.1453821792280867 0.0319223027550292 1.745679012345679 4.548148148148148 1.1368717941323 0.2457507117503182 1.2159484823715767 1.4039724163790972 1.161880305109492 0.2643265801751675 1.0 0.1403531442218371 0.003389670482849 0.0069928111010265 0.0181161163925661 +Membrane microdomain 10 67 2.1233881135800767 0.0337213424277467 14.75485436893204 63.49029126213592 0.5762129399877682 0.5023556315347317 6.545256989336744 6.436953608643344 1.167657055169838 0.3823949317010994 0.1905653591126942 0.0628751933518709 0.0374501301139485 0.1888024401065534 0.1508882561708747 +Nuclear envelope lumen 1 5 2.107499995322355 0.0350742620961397 1.5922330097087378 4.730582524271845 0.2740214243637495 0.4274662744917171 1.0138544466097483 0.5098416377826835 1.1584731829510644 0.3162624936844113 1.0 0.0279227766388577 0.0557540441617295 0.0081566962170519 0.0310935661517569 +Mitotic spindle microtubule 2 8 2.08150094761799 0.0373880774527126 2.0825242718446604 6.441747572815534 0.5708907058485942 0.4767644436015336 1.3027176362136732 1.6381391450699827 0.8609171719873856 0.3046846082742396 1.0 0.0595353304203936 0.1169218221283287 0.2721697661507766 0.0227185425065092 +Postsynaptic specialization membrane 4 13 2.041585443637699 0.0411926704238385 2.4199029126213594 10.24271844660194 0.7861101002372709 0.3813630835285081 1.6578416165380507 2.0900412009571863 0.9115241808638076 0.2917173074219844 0.0433751782957271 0.1762218760282218 0.3247664853085903 0.0756846958642696 0.0473239117869584 +Side of membrane 24 83 2.0257728953644016 0.0427880627104 17.526699029126213 71.19660194174757 0.4235531336200628 0.5236659753791312 6.9409272887607125 8.635706418493163 1.198097658489356 0.36822581052137 1.0 0.6956428968087056 0.0885542952356553 0.0793833993190269 0.0346543616361005 +Ficolin 1 rich granule membrane 3 18 2.025672125619532 0.0427983949696244 4.395631067961165 17.803398058252426 0.1552184768165 0.4321380562295095 2.362999644561935 1.270535437467333 1.1498286388022771 0.2935073244440836 0.0350485247168987 0.1444128696349771 0.0390718495583504 0.1887844423268079 0.0743636419116672 +Golgi apparatus subcompartment 30 114 2.008932739165889 0.0445442673199092 23.898058252427184 88.56796116504854 0.6438651907142603 0.5157075238910589 9.044082768463602 13.85685287398648 1.2182273227220288 0.3801323692583779 1.0 0.3695149225681357 0.0456208533934453 3.2950420100644296e-05 2.383355120642992e-05 +Cell leading edge 36 128 2.008639393529137 0.0445753903944106 28.808252427184467 114.44174757281552 -0.1991917740572248 0.672044075129004 11.981767291657192 11.69636093329509 0.7227206919436855 0.3024789588236066 1.0 0.2000725764580962 0.3802493749582022 0.1697718510526757 0.029865567868342 +Platelet alpha granule lumen 4 13 2.007415819158681 0.0447054058156874 3.094660194174758 11.072815533980584 0.6725356672918105 0.3876488961533653 1.8442433739601936 1.3309383633877778 0.9473857774935364 0.2732835416220931 1.0 0.1155957163384056 0.2202973788945578 0.1292409073430241 0.0075122167669424 diff --git a/msigdb_gocc/metrics.json b/msigdb_gocc/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..23b58446b5213b7185a5c9caa0806280791b4639 --- /dev/null +++ b/msigdb_gocc/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 912, + "title": "Average number of proteins per term", + "value": 32.31688596491228 +} \ No newline at end of file diff --git a/msigdb_gocc/paths.json b/msigdb_gocc/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..b5614fee93721b2f9418f65a5409307e5bd99277 --- /dev/null +++ b/msigdb_gocc/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gocc/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gocc/result.tsv b/msigdb_gocc/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ae17e72583729ddb5c57d46f5cdfe08202233627 --- /dev/null +++ b/msigdb_gocc/result.tsv @@ -0,0 +1,355 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Vacuolar membrane 0.4770553700022522 3.5657651422842633 0.0003627961616063 0.281744650442413 0.0122544481253715 147 Q14108,P42785,O15118,Q8WTV0,Q9HD42,P30511,Q01650,P10253,O75503,Q8TCT8,P20645,Q9UIQ6,Q9Y487,Q07065,O75787,O14678,Q9BXS4,Q8NHS3,P42892,Q92542,P10619,P07602,Q8IV08,P55735,Q93050,P41440,Q9NRA0,O15260,Q99523,P15291,P11117,O75955,Q9NQX7,Q9NUN5 34 +Lysosomal lumen 0.6878769811649655 3.383473503718057 0.000715751135083 0.4795173659098412 0.0181323620887704 37 Q14108,P10253,O14773,P54802,Q9UM22,P06280,P16278,P15586,Q8NHP8,P10619,O00754,P07602,Q8IV08,P50897,Q9UMR5,P08236,P04066,O00584,P61916,P11117,O43681 21 +Vacuolar lumen 0.5489997678888506 3.1826978389300504 0.0014590979600344 0.7359638078644946 0.0341204446038815 69 Q14108,P78371,P10253,O14773,P54802,Q9UM22,P06280,P16278,P15586,Q8NHP8,P10619,O00754,P07602,Q8IV08,P50897,Q9UMR5,P08236,P04066,O00584,P61916,Q9BTY2,P11117,O43681 23 +Cell surface 0.5176405160342399 3.070144053998903 0.0021395554749807 0.8582038768514918 0.0475920632483532 95 Q4VCS5,P26038,Q8WTV0,Q9BQT9,P30511,P14174,Q01650,O75298,Q9H813,P00390,P05067,P11717,P10321,P02786,O75787,P42892,P00813,O75592,P51790,Q13641,P30533,O15484,P78536,P41440,P17655,Q9NWH9,Q99523,P25705,P15291,O75955 30 +Vacuole 0.4679838521228326 2.942145542536579 0.0032594669530479 0.949079465837077 0.0660585302484376 249 Q14108,P42785,P78371,O15118,Q8WTV0,Q9HD42,Q9HC07,P30511,Q01650,P10253,O14773,Q9UM22,P54802,O75503,Q8TCT8,Q8NCC3,P06280,P16278,Q9UHG3,P19474,P20645,Q9UIQ6,Q9Y487,Q07065,O75787,P15586,O14678,Q9BXS4,Q8NHS3,P42892,P00813,Q8NHP8,Q92542,P10619,Q14457,P33176,O00754,P07602,Q8IV08,P50897,P55735,Q8IY95,Q96RU3,Q9UMR5,P51790,Q93050,P08236,P51798,P41440,Q9NRA0,P04066,Q15012,O00584,P61916,P51809,P17655,O15260,Q15165,Q86YV9,Q99523,Q9BTY2,P15291,P11117,Q969Q5,O43681,O75955,Q9NQX7,Q9NUN5 68 +Endocytic vesicle 0.4982568087798361 2.909599355901146 0.003618923390956 0.9633537667651922 0.071749089838085 100 Q14108,Q4VCS5,Q8WTV0,P30511,O43493,Q5KU26,Q16625,P11717,P10321,P20645,Q06481,Q9Y487,P02786,Q9BZG1,Q14457,P33176,O00461,P51790,Q9Y4G8,Q93050,O43752,P61020,P04439,Q9H223,P51809,P08670,Q13555,Q969Q5,Q9NUN5 29 +Azurophil granule 0.5027311325709249 2.7903332628121253 0.0052653812859619 0.9918904633024298 0.0960405546559467 75 P78371,P42785,P10253,P06280,P16278,Q07065,P15586,Q92542,P10619,O00754,P07602,P08236,P04066,O00584,P61916,O15260,Q9BTY2,P15291,O43681,Q9NQX7 20 +Secretory granule membrane 0.4978324408790183 2.739837246021364 0.0061469615209248 0.9963874083816654 0.1057741303223297 75 P11717,P42785,P07602,Q9NQX7,Q06481,P84095,O15260,O75787,P30519,Q07065,Q93050,P15291,P10253,O75592 14 +Apical plasma membrane 0.5329680524289881 2.7254384428361695 0.0064216149623532 0.9971923231253932 0.1084539415864108 54 P11166,P55011,P26038,P53985,O75787,Q01650,P51790,Q9Y4G8,O14523,P30825,O43865,P78536,O75955,P41440,Q9Y6M7 15 +Azurophil granule membrane 0.6556653625373653 2.5723453441188138 0.0101012075552375 0.999904763252833 0.1485855046834947 25 P42785,P07602,O15260,Q07065,P15291,P10253,Q9NQX7 7 +Presynaptic active zone 0.6801354993561112 2.556398148381084 0.010576202794662 0.9999385241305884 0.1505840171653195 18 Q7L0J3,P41440,P05067,O75955 4 +Endocytic vesicle membrane 0.5166950728766841 2.533420913463988 0.0112955226160549 0.999968329946173 0.1505840171653195 50 P11717,Q14108,P20645,Q06481,Q8WTV0,Q9Y487,P02786,Q13555,P30511,O43493,Q5KU26,Q93050,Q9BZG1 13 +Proteasome core complex beta subunit complex 0.9137222768796688 2.5268994704617342 0.011507443681116 0.9999739538348408 0.1505840171653195 7 P28074,P20618,P28072,Q99436,P49721 5 +Endoplasmic reticulum lumen 0.4810943416819119 2.509169332378961 0.0121015457632569 0.9999849470030492 0.1534425863991456 69 Q02818,P07942,Q14257,Q06481,O00584,Q86UP2,Q8NBJ4,Q9NZ08,Q07065,O43493,Q9BTY2,O43681,Q9NWW5,P78536,Q8IXB1,P05067 16 +Vesicle lumen 0.4245567697124711 2.5088092385598992 0.0121138883999325 0.9999851175501108 0.1534425863991456 131 Q08380,P78371,P20618,P14174,Q8N2G8,P06280,P05067,P16278,O00231,Q8WVQ1,P15586,P00813,Q13813,P10619,O00754,P12814,O15078,Q8NBX0,Q13464,O43707,P12956,Q7L576,Q9NUQ9,P04066,O00584,P61916,Q9BTY2,O43681,Q99436 29 +Proteasome core complex 0.729066613636542 2.4695578215526095 0.0135280153970891 0.9999959700704576 0.1641715820653282 15 P28070,P28074,P20618,P28072,Q99436,P49721 6 +Dopaminergic synapse 0.9327107937379828 2.431908260218652 0.0150195109765465 0.9999989860965224 0.164956869643316 2 P41440 1 +Postsynaptic density membrane 0.8186941197389415 2.385347742874558 0.0170629838685851 0.999999847443895 0.1788671412430998 9 Q9BQT9,Q99720,P57105,Q14168 4 +Intrinsic component of organelle membrane 0.3947870906853468 2.380306804021398 0.0172982290550285 0.99999987736182 0.1792725556612048 149 Q86XL3,O15118,Q9P2E9,O96008,Q15629,P30511,Q8N2H4,Q99595,Q7L0J3,Q13505,Q99442,Q9HCU5,O75298,Q9Y5Z9,Q8TCT8,Q9HC21,Q9UBM7,O95563,Q8N4V1,P10321,Q9UH99,Q9NWR8,Q86UP2,Q8TB61,Q14739,Q15070,P42892,Q9BPX6,Q9BUB7,Q969N2,Q5H8A4,P50336,Q5SNT2,Q9Y282,Q16891,O60499,Q9H3K2,O43505,Q9Y2U8,Q9Y4W6,Q6P4A7,O43752,O75431,P61020,P04439,O95070,O95470,Q9Y2R0,Q9NX63,Q5T9L3,Q9H4I9,P57105,Q9NXW2,O75844,Q9GZY8 55 +Apical part of cell 0.4648033718346674 2.364597730278956 0.0180496643677661 0.9999999389557312 0.1831974334001766 70 P11166,P55011,P26038,Q99538,P53985,O75787,Q01650,P51790,Q9Y4G8,O14523,P30825,O43865,P78536,O75955,P41440,P05067,Q9Y6M7 17 +Ciliary rootlet 0.9126613567701158 2.3482943163611028 0.0188596122853317 0.9999999712384756 0.1890106198266212 2 P05067 1 +Nuclear inner membrane 0.6207360218889015 2.3250748499479297 0.0200679581992928 0.9999999906520988 0.1967954610511299 24 P20700,Q99720,Q9UH99,Q03252,Q14739,O75844 6 +Cuticular plate 0.8989288656962353 2.290615840547978 0.0219856419540001 0.9999999984337888 0.2110621627584009 2 Q9Y5X1 1 +External side of plasma membrane 0.5978478562509154 2.281681984814331 0.0225081224375096 0.999999999037946 0.2138271631563417 27 P02786,P17655,P30511,O75787,Q01650,P51790,P15291,P42892,O75955,P00813,P00390,P41440 12 +Neuromuscular junction 0.6210385151836065 2.2407423310751313 0.025042770394114 0.9999999999098772 0.2283900659943203 20 Q7L0J3,P57105,Q14168,P07196,P05067,P46939 6 +Clathrin coated vesicle 0.475797258421253 2.210708589083223 0.0270560233692866 0.9999999999863194 0.2382188622746271 55 P11717,Q14108,P20645,P02786,Q9Y5X1,O43493,Q99523,O43752,P42892,O00291,Q5VW38,Q9NUN5 12 +Ciliary transition zone 0.7387087836736504 2.2091341870408603 0.0271653088558785 0.9999999999876517 0.2382188622746271 11 Q15051,Q15555,O15078,A6NIH7,Q9Y366,Q9UPN4 6 +Early endosome 0.4194525978526018 2.197369554975111 0.02799406379251 0.999999999994324 0.2431484397978013 118 Q8WUH2,Q9HD42,Q9HC07,Q96C92,P30511,Q96PE3,P14373,Q5VW38,P05067,Q9Y5X2,P11717,Q8N4V1,P10321,Q06481,Q9UIQ6,P02786,Q96L92,Q9Y6W5,Q92542,Q8IV08,P51790,O43752,P61020,P04439,O15400,P41440,Q9H223,Q567U6,Q15075,Q86YV9,Q99523,P31751,O95219,O75955,Q9NWW5 35 +Basal part of cell 0.4646798427359156 2.184375795581073 0.028934645304715 0.9999999999976524 0.2466205282046737 61 P11166,P42785,Q9BY67,P02786,P53985,Q9NWH9,Q96N67,Q01650,Q14168,P15291,Q6P4Q7,P57105,P30825,O75955,P41440,Q9Y6M7,O14936 17 +Perinuclear region of cytoplasm 0.4064100015457815 2.1761368003367942 0.0295450329139548 0.9999999999986772 0.2494913890511741 211 P07942,Q01105,P26038,O15118,O94788,O14976,Q12834,O75503,P05067,P16278,P11717,P20645,Q9UIQ6,Q9Y487,P02786,Q07960,Q07065,O95831,O75935,P42892,Q9H2J4,Q9BZG1,O75592,P33176,O60499,Q15056,Q8IY95,O43707,O60858,Q9Y4G8,Q93050,Q96F07,O43752,Q7L576,Q9BZE4,Q9H223,Q9H4L5,O75569,Q9UNS2,P17655,Q15437,Q99523,O95684,Q99538,Q9NQX7 45 +Schmidt lanterman incisure 0.8703652842625627 2.1695972630860996 0.0300373689063673 0.9999999999991672 0.2503044884055461 2 Q8N3R9 1 +Platelet alpha granule 0.6060766130043401 2.148626445055186 0.0316640236433707 0.9999999999998198 0.2531577401094495 20 Q9NUQ9,P12814,Q8NBX0,Q06481,P05067 5 +Golgi lumen 0.8669291804790634 2.1453821792280867 0.0319223027550292 0.9999999999998588 0.2531577401094495 6 Q9BRK5,O00461,P05067,Q9NX62 4 +Equatorial microtubule organizing center 0.8632243889041445 2.139125517370854 0.032425504311548 0.999999999999912 0.254931551139067 2 Q96CW5 1 +Membrane microdomain 0.4481265054533855 2.1233881135800767 0.0337213424277467 0.999999999999974 0.2606259685941102 67 P21796,O15118,P50897,Q8WTV0,P25705,O75955,Q9NWW5,P78536,P41440,P05067 10 +Nuclear envelope lumen 0.8978813230021286 2.107499995322355 0.0350742620961397 0.9999999999999928 0.2665643919306619 5 P05067 1 +Mitotic spindle microtubule 0.7793741301915232 2.08150094761799 0.0373880774527126 0.9999999999999992 0.2758108679508005 8 Q9H6D7,Q96CS2 2 +Postsynaptic specialization membrane 0.683223775407526 2.041585443637699 0.0411926704238385 1.0 0.2801427783696173 13 Q9BQT9,Q99720,P57105,Q14168 4 +Myosin filament 0.9186589722451232 2.0406611231194356 0.0412845221425666 1.0 0.2801427783696173 4 P35579,P35580,Q13049 3 +Myosin ii complex 0.917995213810922 2.0381327658195825 0.0415366571335287 1.0 0.2801427783696173 4 P35579,P35580 2 +Side of membrane 0.429939543077183 2.0257728953644016 0.0427880627104 1.0 0.2801427783696173 83 Q4VCS5,P30511,Q01650,Q9H1P3,O00291,Q8TCT8,P00390,P35579,P10321,P02786,Q00536,O75787,Q9UBI6,P42892,P00813,P10619,P51790,O14523,P04439,P41440,P17655,Q9Y5X1,P15291,O75955 24 +Ficolin 1 rich granule membrane 0.5911197321265454 2.025672125619532 0.0427983949696244 1.0 0.2801427783696173 18 Q93050,P42785,P10253 3 +Golgi apparatus subcompartment 0.4092684596647197 2.0089327391658895 0.0445442673199092 1.0 0.2821902981786454 114 Q4J6C6,Q9HC07,O43493,P05067,P11717,P20645,Q8WVQ1,Q96L58,Q08379,Q9NPR9,Q9BXS4,Q96ED9,Q9BZG1,O75592,Q14457,O60499,O15127,O00461,Q8IWJ2,O43752,O60512,Q969M3,Q8NBN3,Q9NX62,P51809,Q96CN9,Q9Y5X1,Q99523,P15291,Q8TBA6 30 +Cell leading edge 0.3927213072163162 2.008639393529137 0.0445753903944106 1.0 0.2821902981786454 128 Q92538,Q4VCS5,Q9Y5S2,Q9UQB8,P05067,Q16625,P35579,P35221,Q06481,O75787,Q10713,Q9BZG1,Q9Y6W5,P23396,P12814,Q9UHB6,Q13464,P51790,Q14168,Q9Y448,O00213,P09493,P78536,Q7L576,P41440,O60749,P31749,P35222,P46940,P35580,P51809,P08670,Q9Y5X1,Q01082,P31751,O75955 36 +Platelet alpha granule lumen 0.6765810426992175 2.007415819158681 0.0447054058156874 1.0 0.2821902981786454 13 Q9NUQ9,P12814,P05067,Q8NBX0 4 +Platelet dense granule lumen 0.8231255149684125 1.9664666824128512 0.0492447272967111 1.0 0.3060049011909951 2 Q08380 1 +Gator2 complex 0.8223015655039789 1.9628922963338504 0.0496586901055562 1.0 0.3060049011909951 2 P55735 1 +Seh1 associated complex 0.8223015655039789 1.9628922963338504 0.0496586901055562 1.0 0.3060049011909951 2 P55735 1 +Dendrite cytoplasm 0.6869146914775387 1.9564976704553871 0.0504065566032008 1.0 0.3085287222961016 11 Q9UQB8,P33176 2 +Haus complex 0.8557725449043133 1.942334412181673 0.0520966296766292 1.0 0.3146498428151379 5 Q9H6D7,Q96CS2 2 +Dendritic shaft 0.8141177248652081 1.9315267210034832 0.0534179481168313 1.0 0.3205076887009879 6 Q9UQB8,P05067 2 +Transport vesicle 0.4084727649218536 1.9084804490317264 0.0563291477253546 1.0 0.3351852650314738 106 P30511,O43493,Q7L0J3,P05067,P11717,P10321,P20645,Q00536,O75592,Q92542,P24390,O60499,P50897,O00461,P55735,P51790,Q9Y678,O43752,P61020,P04439,P51809,P35606,O15260,Q15437,Q99523,Q9BT78,Q8TBA6,Q9GZY8 28 +Centriole 0.5123996586265975 1.9063927685657749 0.0565992662443497 1.0 0.3351852650314738 32 Q15051,Q96CW5,Q9Y496,O15078,Q9Y5Y2,Q13464,Q86SX3,Q14203,O95684,Q9Y366,Q9UPN4 11 +Perinuclear endoplasmic reticulum 0.7635577320726418 1.9022715591544312 0.0571356618486835 1.0 0.3361788619741898 7 O60858,Q9H4L5 2 +Golgi trans cisterna 0.9010989010989012 1.883828744698025 0.0595881440574423 1.0 0.3439518188632117 3 Q9BXS4,P15291 2 +Cell body 0.4049859504663625 1.864762329942105 0.0622147256533656 1.0 0.3568542754457197 106 P78371,Q7L0J3,Q8N3R9,Q9UQB8,P05067,P22466,O75787,Q14203,O75251,Q15375,O75592,P55011,P50897,Q9Y4G8,Q14168,Q7L576,P17655,P10586,Q9H2U1 19 +Rna polymerase ii transcription repressor complex 0.7986816808569066 1.859998948960069 0.0628856746636072 1.0 0.3584483455825615 2 Q9UHI6 1 +Endosome lumen 0.8313984095960684 1.8455556913777609 0.0649567451069925 1.0 0.3634940436550589 5 Q9UIQ6,P30533,P05067 3 +Myosin complex 0.6714372864190821 1.835819824379212 0.06638430848993 1.0 0.3634940436550589 10 P35579,P35580 2 +Vacuolar proton transporting v type atpase v0 domain 0.8648746130391158 1.8339029978392205 0.0666683945056356 1.0 0.3634940436550589 4 Q9Y487,Q93050 2 +Proton transporting v type atpase v0 domain 0.8648746130391158 1.8339029978392205 0.0666683945056356 1.0 0.3634940436550589 4 Q9Y487,Q93050 2 +Ciliary basal body 0.5294379987563913 1.8143171917280696 0.069628906287821 1.0 0.371641100511366 27 P48729,O15078,P28070,Q96C92,Q8IUD2,O75419,Q96RK4,Q9Y366,O43805,Q9UPN4,A0AVF1 11 +Neurofilament 0.8559277190825533 1.7991573138346837 0.07199379958878 1.0 0.3769488959177197 4 P07197,P07196 2 +Cortical actin cytoskeleton 0.491070627817133 1.7938894412582191 0.0728308170854132 1.0 0.3773960521698688 33 P35579,P11166,P12814,Q9Y5X1,O43707,Q9NS86,O75955,P41440,Q13813,P46939 10 +Cell trailing edge 0.7800077803621177 1.7910278821934702 0.0732888207833575 1.0 0.3776237545447574 6 P35579,P41440,O75955 3 +Intrinsic component of plasma membrane 0.4017078565725841 1.7816451227287209 0.0748071211661269 1.0 0.3791161982647865 101 O15118,Q8WTV0,Q9BQT9,Q9H813,Q99805,P05067,P11717,P11166,P20645,Q9UIQ6,P02786,Q86UP2,P53985,P16615,Q15375,P30825,Q92542,P55011,Q8NBJ4,P51790,Q13641,Q9Y4G8,Q9NPF0,P78536,P41440,O60637,Q9NWH9,P10586 28 +Intrinsic component of synaptic vesicle membrane 0.6588239522221786 1.773918450516527 0.0760766403688499 1.0 0.3791161982647865 10 O60499,Q86Y82,O76024,Q7L0J3,O43752,P61020 6 +Compact myelin 0.8706043956043961 1.766453770146096 0.0773197509618972 1.0 0.3791161982647865 3 Q9NR77,Q8N3R9 2 +Gamma secretase complex 0.7753364460313064 1.7575412508086887 0.0788255970951588 1.0 0.3844328585603466 2 Q92542 1 +Dendrite terminus 0.8430478593248529 1.7489753748845216 0.0802952761198991 1.0 0.3895175096880215 4 Q9Y366 1 +Microtubule associated complex 0.4285244582961343 1.7367284519601336 0.082435113210443 1.0 0.3915667877496045 53 Q15555,O15344,Q9Y496,P49354,Q14203,P52732,Q9H6D7,Q96CS2,O75935,O95219,P29372,P33176 12 +Actomyosin 0.4988451416623957 1.711966712675404 0.0869028030418015 1.0 0.4057581599076847 30 P35579,P12814,P35580,Q7Z406,O43707,P09493,P67936,Q9Y5S2 8 +Uniplex complex 0.7976733471071815 1.7103432874412896 0.0872024115591076 1.0 0.4057581599076847 5 Q9H4I9,Q8IYU8,Q9NWR8 3 +Presynapse 0.3908901647430508 1.6956503633042506 0.0899521139176615 1.0 0.4093500224462661 107 P51114,Q13136,Q7L0J3,O14976,O00291,Q9UQB8,P05067,P11166,Q00536,Q8IUD2,Q92542,O14936,O60499,Q9NZM3,P50897,P51790,Q13641,O43752,P61020,Q7L576,P41440,Q9BT78,O75955,P07196,Q9GZY8 25 +Pore complex 0.642563110779256 1.6936061021703357 0.0903401577290363 1.0 0.4093500224462661 10 P21796 1 +Golgi associated vesicle 0.4672892623225017 1.6912185282133727 0.0907950735606903 1.0 0.4093500224462661 36 O43493,Q99523,Q8TCT8,P05067,Q8NDZ4 5 +Exocytic vesicle 0.4488921426859721 1.6877534249080637 0.0914585715794318 1.0 0.4093500224462661 43 O60499,P50897,Q00536,P51790,Q7L0J3,O43752,Q9BT78,P61020,Q92542,P05067,Q9GZY8 11 +Filopodium 0.4774566600932309 1.6873532367662127 0.0915354500083256 1.0 0.4093500224462661 33 Q9H4L5,P26038,P15291,Q7L576,Q9UQB8,P05067,P46939 7 +Cortical cytoskeleton 0.4458131377625969 1.687198776483851 0.0915651365998226 1.0 0.4093500224462661 44 P35579,P11166,P12814,Q9Y5X1,O43707,Q9NS86,O75955,P67936,P41440,Q13813,P46939 11 +Clathrin coated endocytic vesicle 0.5268381070546647 1.6745471982137965 0.0940231065674792 1.0 0.4182881619002003 22 P11717,Q14108,P20645,P02786,O43493,Q9NUN5 6 +Azurophil granule lumen 0.4377303377490654 1.6715400445677324 0.094615055946907 1.0 0.4188783059397047 46 P16278,O00754,P78371,P04066,O00584,P61916,P15586,Q9BTY2,O43681,P10619,P06280 11 +Caveola 0.5820418604114315 1.6664997013771232 0.095613927626408 1.0 0.4212555651946095 15 Q8WTV0,P41440,O75955 3 +Integral component of synaptic vesicle membrane 0.7488371890537511 1.661162998882878 0.0966807146151897 1.0 0.4232019803394732 6 Q7L0J3,O60499 2 +Cell cell junction 0.3757296536646557 1.6582923075868743 0.0972584809129903 1.0 0.4232019803394732 121 Q4VCS5,P26038,Q86VI3,Q7L0J3,Q92797,Q8N3R9,O00192,Q9Y5S2,Q9UQB8,P05067,Q16625,Q9NR77,P35579,P11166,P35221,Q9BY67,O14936,P12814,Q96TA1,Q9Y4G8,Q14168,P78536,Q9BX67,P41440,P15291,O75955,Q9UEY8 27 +Phagocytic vesicle 0.4203992889043995 1.650637706152018 0.098812574729189 1.0 0.4232019803394732 52 P10321,Q06481,P51809,Q9Y487,P08670,P30511,P51790,Q93050,O43752,Q9BZG1,Q14457,P33176 12 +Photoreceptor connecting cilium 0.6824273096232413 1.647987286460808 0.0993552800992525 1.0 0.4234206329463472 8 Q9Y366,Q15051,Q15555,O15078 4 +Proton transporting v type atpase complex 0.6150394538991115 1.6379191276459062 0.1014385652676268 1.0 0.4282504798355943 12 Q9Y487,Q93050 2 +Basolateral plasma membrane 0.4187357246486626 1.6344130137772146 0.1021721575084606 1.0 0.4282504798355943 52 P11166,Q9BY67,P02786,P53985,Q01650,Q14168,P15291,Q6P4Q7,P57105,P30825,O75955,P41440,Q9Y6M7,O14936 14 +Proton transporting two sector atpase complex 0.512829791998153 1.6336618507566711 0.102329872920782 1.0 0.4282504798355943 25 Q9Y487,P00846,P25705,Q93050,O75964 5 +Flotillin complex 0.742233257314548 1.6334856754163032 0.1023668910133328 1.0 0.4282504798355943 6 P41440,P35221,O75955 3 +Neuron to neuron synapse 0.3969906329353098 1.6311087647404685 0.1028673716049157 1.0 0.4283791913410191 70 P23396,Q14012,Q99720,P55795,Q9BY67,P51114,Q9BQT9,P51991,Q96PE3,Q15375,Q14168,P57105,Q01082,Q9UQB8,P11274,Q9UEY8 16 +Golgi cis cisterna 0.8342111860791561 1.6251431621825 0.1041320578765589 1.0 0.4285023267929103 3 Q9BXS4 1 +Golgi apparatus 0.3997339676130468 1.6100743286706078 0.1073816306098516 1.0 0.4341232509103521 387 Q7RTS9,Q5VW38,O75503,Q9UQB8,P05067,P20645,P22466,Q15392,Q9NPR9,Q9BXS4,Q8NDZ4,Q02818,Q8N2A8,Q8IV08,P50897,O00461,Q8NBJ4,Q93050,O60512,P80303,Q9BRK5,Q9Y5X1,O15260,Q99523,P15291,Q9NQX7,Q4J6C6,Q92896,Q8IZA0,P30511,O43493,Q8N3R9,P06280,P16278,P11717,Q8N4V1,Q96ED9,Q9Y6K0,O75592,Q14457,Q9Y282,O60499,O15127,O43505,Q5VU43,P78536,Q8NBN3,Q68CQ7,Q9NX62,O95456,Q14108,O15118,Q9BQT9,Q8TD16,O60476,Q9Y5Z9,P11166,Q96L58,Q92542,Q16739,Q13464,Q9H9S5,Q969M3,Q15012,Q96CN9,Q8TBA6,Q9HC07,O14976,O14773,O00291,Q99805,Q8NCH0,Q8WVQ1,Q08379,Q9BZG1,Q8IY95,Q8IWJ2,P51790,P30533,O43752,Q9BX67,Q5SRI9,P51809,P17655 84 +Trans golgi network 0.3938697054190593 1.6084779899808022 0.1077305328974671 1.0 0.4341232509103521 80 P11717,O60499,P20645,O15127,Q4J6C6,Q9NX62,Q9HC07,P51809,Q9Y5X1,Q8IWJ2,O43493,Q9NPR9,Q96ED9,O43752,Q14457,O75592,Q969M3,P05067 18 +Actin based cell projection 0.4165173482967592 1.6069980293958666 0.1080548003910635 1.0 0.4341232509103521 51 Q9H4L5,P26038,Q7L576,Q01650,P15291,Q9BX67,Q9UQB8,P05067,Q9Y6M7,P46939 10 +Myofilament 0.7325775608030011 1.5929242380641655 0.1111771881078738 1.0 0.4379683374558835 6 P67936,Q13049,P09493 3 +Somatodendritic compartment 0.346466703053354 1.591555563850075 0.1114846012674302 1.0 0.4379683374558835 155 Q9BQT9,Q13136,Q7L0J3,Q8N3R9,Q9Y366,Q9UQB8,P05067,P22466,O75787,Q14203,O75251,Q15375,O75592,Q14457,P33176,P12814,P55011,P50897,Q13641,Q9Y4G8,Q14168,Q7L576,P11274,P17655,P10586,Q9H2U1,P23246 27 +Mhc class i protein complex 0.801596951340724 1.586302900798722 0.1126706146014386 1.0 0.4379683374558835 4 P30511,P10321 2 +Mhc protein complex 0.801596951340724 1.586302900798722 0.1126706146014386 1.0 0.4379683374558835 4 P30511,P10321 2 +Lipid droplet 0.4563637253409741 1.5852624570234648 0.1129067151981391 1.0 0.4379683374558835 35 Q92538,P60604,Q99720,Q01105,Q8N0X7,Q8NBX0,Q07065,Q9H1P3 8 +Lumenal side of membrane 0.6044495581688432 1.5826554760638636 0.1135000116430267 1.0 0.4379683374558835 12 Q8TCT8,P30511,P10321,P10619 4 +Proton transporting two sector atpase complex proton transporting domain 0.6033856628255336 1.5770909590469953 0.1147745972060922 1.0 0.4379683374558835 12 Q9Y487,Q93050,P00846,O75964 4 +Secretory vesicle 0.3870671018738543 1.5619917334932063 0.1182899362784553 1.0 0.4461165095818515 283 P42785,Q08380,P78371,P84095,P20618,P30519,P14174,Q8N2G8,Q7L0J3,P10253,Q9UQB8,P05067,P06280,P16278,P11717,P35579,O00231,Q8WVQ1,P22466,Q06481,Q9Y487,Q07065,O75787,P15586,P42892,O75592,Q92542,P10619,Q13813,O00754,P12814,O60499,P07602,O15078,P50897,Q8NBX0,Q13464,P45880,O43707,P51790,Q93050,P12956,P08236,Q7L576,Q9NUQ9,P04066,O00584,P61916,O15260,Q9UPN4,Q9BTY2,P15291,Q9BT78,O43681,Q99436,Q9NQX7,Q9GZY8 57 +Excitatory synapse 0.7237228909990074 1.5556352991219509 0.1197948398919723 1.0 0.4496003867550567 6 Q9UQB8 1 +Secretory granule 0.3789929966761137 1.5434352565088585 0.1227252049024651 1.0 0.4568383137593806 253 P42785,Q08380,P78371,P84095,P20618,P30519,P14174,Q8N2G8,P10253,Q9UQB8,P05067,P06280,P16278,P11717,P35579,O00231,Q8WVQ1,P22466,Q06481,Q9Y487,Q07065,O75787,P15586,P42892,O75592,Q92542,P10619,Q13813,O00754,P12814,P07602,O15078,Q8NBX0,Q13464,P45880,O43707,P51790,Q93050,P12956,Q7L576,Q9NUQ9,P04066,O00584,P61916,O15260,Q9UPN4,Q9BTY2,P15291,O43681,Q99436,Q9NQX7 51 +Specific granule membrane 0.5440729236595971 1.533991540828698 0.1250317338647093 1.0 0.463532281644776 16 P30519 1 +Centriolar satellite 0.4742215069809865 1.528155161004101 0.126474018579566 1.0 0.4656710165351196 30 Q13045,O15078,Q9UPT5,Q8WXW3,Q86VS8,Q9UPN4,Q9Y448,Q9Y6A5,O75955,Q96RK4,P41440,P33176 12 +Organelle envelope lumen 0.4383189528408055 1.525475892640179 0.1271404420145228 1.0 0.4656710165351196 40 P11717,O60313,P52888,O00584,P17655,O95831,Q9BRT2,Q9BPX6,Q8IYU8,P05067,P50336 11 +Mitochondrial crista 0.8028589214226999 1.5025493944030883 0.1329552814583214 1.0 0.4850208667599567 3 Q9BUB7 1 +Coated vesicle 0.3744481279089921 1.4845689636301556 0.1376580420777389 1.0 0.4962986063953572 107 Q14108,P30511,O43493,O00291,Q5VW38,P05067,P11717,P10321,P20645,Q08379,P02786,P42892,P24390,Q8NDZ4,Q9Y282,P55735,Q9Y678,O43752,Q969M3,P51809,Q9Y5X1,P35606,Q15437,Q99523,Q9NUN5 25 +Golgi cisterna 0.4458043666730185 1.484488664024738 0.1376793283092383 1.0 0.4962986063953572 34 Q8WVQ1,Q96L58,Q08379,O00461,Q10472,Q96CN9,Q96JB2,Q99523,Q9BXS4,P15291,O60512,Q8TBA6,Q9BZG1,Q8NBN3 14 +Fhf complex 0.794505494505495 1.469785816322602 0.1416197717927301 1.0 0.5025833670231331 3 Q9UJC3,Q96ED9 2 +Plasma membrane raft 0.4998671162767847 1.4697587266833556 0.1416271111019136 1.0 0.5025833670231331 20 Q8WTV0,P41440,O75955 3 +Outer mitochondrial membrane protein complex 0.5461186399573795 1.4607592593051348 0.144081519993886 1.0 0.5053936393631696 15 O96008,Q13505,O75431,Q9NX63 4 +Cohesin complex 0.7315394992080453 1.4415852643615152 0.1494194079008302 1.0 0.5142283019077628 5 Q9UQE7,Q8WVM7,Q8N3U4 3 +Cell projection membrane 0.3769949196767374 1.4187234108745728 0.1559796691831132 1.0 0.5275616707940335 74 P23396,P55011,Q96RK4,P41440,Q06481,O14936,O75787,Q01650,P51790,Q14168,Q01082,P31751,P15291,Q9BZG1,P78536,P09493,P46939 17 +Mismatch repair complex 0.7541167678312207 1.398282809980139 0.162028157840012 1.0 0.53393057143502 4 P20585 1 +Early endosome membrane 0.3922301956987333 1.397886392416165 0.162147185569603 1.0 0.53393057143502 56 Q8N4V1,P10321,Q15075,Q8IV08,Q06481,Q9HC07,Q96PE3,P30511,P51790,Q96L92,Q86YV9,O95219,P61020,P04439,O15400,Q9H223,Q9Y5X2 17 +Trans golgi network membrane 0.4351579767702526 1.3978114267282566 0.1621697020696277 1.0 0.53393057143502 34 P11717,O60499,O15127,P20645,P05067 5 +Cop9 signalosome 0.5754414831565987 1.3915476839261471 0.16405941052273 1.0 0.5382092891968696 11 Q9UNS2,Q9BT78,P61201,Q9H9Q2 4 +Centrosome 0.3491776533141823 1.389460532027351 0.1646927544903951 1.0 0.5383505093019367 191 Q13045,Q9Y496,Q96C92,Q8TD16,O75419,Q9H6D7,Q12834,Q9Y366,Q9Y6D9,Q13432,O75330,Q96CW5,P28074,P53985,Q8IUD2,Q14203,O75116,O75935,Q96ED9,O43805,Q9H981,P55081,Q6DKK2,P33176,P48729,Q9NZM3,O15078,Q8WXW3,Q5VU43,Q9Y448,Q8N1F7,P41440,Q15051,Q9Y5Y2,O94927,Q96CS2,O95684,Q9BSJ2,O75955,Q96RK4,Q9UPN4,A0AVF1 42 +Ruffle 0.3815539467811441 1.354080536050868 0.1757106851668777 1.0 0.5606369985036918 63 Q4VCS5,Q9UQB8,P35579,Q06481,Q10713,Q9BZG1,Q9Y6W5,P23396,P12814,Q9UHB6,Q13464,P51790,Q9Y448,P09493,P78536,Q7L576,P46940,Q9Y5X1,P31751 19 +Neuron projection terminus 0.4986237136769474 1.3470559266435287 0.1779622212370426 1.0 0.5635470339173018 17 Q13641,Q7L576,Q9UQB8 3 +Neuron projection membrane 0.571401909504386 1.3364880119465 0.1813898162684475 1.0 0.5672652558746571 10 Q14168,O75787 2 +Presynaptic membrane 0.4777299537311563 1.3341313858153798 0.1821608014104425 1.0 0.5672652558746571 21 Q06787,Q9NZM3,Q8IUD2,O00291,P19022,Q92542,P35222,O14936 8 +Tight junction 0.4548007625521989 1.3129938946409858 0.1891850054746124 1.0 0.5809317339826484 28 Q9NR77,Q9Y4G8,Q92797 3 +Intrinsic component of nuclear inner membrane 0.6288512469991764 1.3094146168753882 0.1903939428477494 1.0 0.5826821338159313 7 Q9UH99,Q5SNT2,Q14739 3 +Lamellipodium 0.3726429110741372 1.2962038162322536 0.1949052751303941 1.0 0.592127887066241 66 P35580,Q4VCS5,P41440,P35221,P51809,Q7L576,Q13464,O60749,O75955,Q9Y6W5,Q9Y5S2,Q9UQB8,P05067 13 +Schaffer collateral ca1 synapse 0.4747289154723466 1.2950392353763014 0.1953066948802593 1.0 0.592127887066241 19 Q15375,Q9UQB8,P11274,P07196,O14936 5 +Neuron spine 0.4136912846875392 1.294264130151991 0.1955742019427653 1.0 0.592127887066241 39 P12814,O75787,Q14168,Q7L576,Q9UQB8,P11274,P05067 7 +Clathrin coated endocytic vesicle membrane 0.5171183921850695 1.2928081055980527 0.1960774362872859 1.0 0.592127887066241 15 P11717,Q14108,P20645,P02786,O43493 5 +Extrinsic component of cytoplasmic side of plasma membrane 0.471133753149471 1.2899992438801722 0.1970509206278259 1.0 0.5931037610976146 21 Q00536,Q9Y5X1,Q9H1P3,Q9UBI6,O00291,P31749 6 +Nuclear pore outer ring 0.5813099334221287 1.278532005647152 0.2010619071556476 1.0 0.5982786134115484 9 Q96EE3,P55735,P57740 3 +Meiotic cohesin complex 0.723553000613477 1.2767681132782196 0.2016841261498443 1.0 0.5982786134115484 4 Q9UQE7,Q8N3U4 2 +Main axon 0.5568189015330179 1.2625059675740042 0.2067667803250956 1.0 0.6068933333936948 10 Q14168,P05067 2 +Phagocytic vesicle membrane 0.4275374859494239 1.248420771183528 0.2118770062665451 1.0 0.6114931320097758 32 Q9Y487,Q93050,Q06481 3 +Striated muscle thin filament 0.6819524523073008 1.2382484788012609 0.2156239409838882 1.0 0.614042649816017 5 P67936,P09493 2 +Dendrite membrane 0.7135243708995518 1.2368928799807084 0.2161268537181375 1.0 0.614042649816017 4 Q14168 1 +Mib complex 0.5481034903777615 1.21823329896149 0.2231353290161262 1.0 0.6242313498856046 10 Q13505,O75431,Q9NX63 3 +Intermediate filament 0.4587178032077788 1.1976389983138616 0.231057586972128 1.0 0.6385591494502448 20 P07197,P20700,P48729,P08670,Q03252,P02545,O75298,P07196 8 +Pole plasm 0.7156777531438395 1.1600969241240573 0.246009346364072 1.0 0.6560249236375254 3 Q9Y2W6 1 +Lumenal side of endoplasmic reticulum membrane 0.5331073267941985 1.1420239121281004 0.2534440803603015 1.0 0.6645430809799439 10 Q8TCT8,P30511,P10321 3 +Ciliary tip 0.5525836445616428 1.1391331471473558 0.2546476239868513 1.0 0.6654402093868437 9 Q9Y366,Q15555,A0AVF1 3 +Proteasome complex 0.3765086366051252 1.128512798398686 0.2591034148897528 1.0 0.6751494696555845 47 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Golgi medial cisterna 0.6544667520044858 1.125579432783362 0.2603435777487402 1.0 0.676448270389889 5 Q96L58,Q9BXS4 2 +Synaptic vesicle membrane 0.4742351723154956 1.1144952888674624 0.2650667644306543 1.0 0.6785042344638957 16 Q7L0J3 1 +Trans golgi network transport vesicle 0.4858777348214889 1.1109346944556795 0.2665964603151469 1.0 0.6785042344638957 15 Q99523,O43493 2 +Acrosomal membrane 0.6289480911837348 1.106351075322985 0.2685745928086254 1.0 0.6785042344638957 2 P35613 1 +Bleb 0.6167594895148081 1.1013660560047054 0.2707373724941204 1.0 0.6799388250458206 6 Q9BRK5,P09493 2 +Golgi stack 0.3852981625860015 1.099892202649285 0.2713790924524986 1.0 0.6799388250458206 42 Q8WVQ1,Q96L58,Q08379,O00461,Q10472,Q96CN9,Q96JB2,Q99523,Q9BXS4,P15291,O60512,Q8TBA6,Q9BZG1,Q8NBN3 14 +Endopeptidase complex 0.3634682939457855 1.0913790098936438 0.275106144594897 1.0 0.6809393706767582 53 O00231,P28070,P28074,P20618,P49721,P28072,Q99436,P60900 8 +Apical junction complex 0.406875073909969 1.0853343385693384 0.2777736024753963 1.0 0.6813331591435725 32 Q9NR77,Q4VCS5,Q9Y4G8,Q92797,Q8N3R9,Q9BX67,Q16625 7 +Outer membrane 0.3462022828454438 1.083274570337848 0.2786865691234925 1.0 0.6813331591435725 101 Q99720,P21796,Q8N2A8,Q9HCL2,P45880,O43169,P57105,Q13505,O75431,Q9GZY8 10 +Brush border membrane 0.5409611613125141 1.0827826760950714 0.2789048967676701 1.0 0.6813331591435725 9 P41440 1 +Snare complex 0.4414432619148455 1.0762108986761791 0.2818329466121914 1.0 0.6813331591435725 19 O60499,P51809,Q86Y82,O43752,O95219,O15400 6 +Endosome 0.3505472919444229 1.0727534447351392 0.2833817540172116 1.0 0.6813331591435725 254 Q14108,Q8WUH2,O15118,Q9HD42,Q9HC07,Q96C92,P30511,Q96PE3,O43493,P14373,O14773,Q5VW38,Q8TCT8,Q99805,P05067,Q9Y5X2,P11717,Q8N4V1,P20645,Q9UH99,Q06481,Q9UIQ6,Q9Y487,P02786,Q07960,O75787,Q9BXS4,P42892,Q92542,Q14457,P07602,Q8IV08,O15127,O00461,Q8IY95,P51790,Q9Y4G8,Q93050,P30533,O43752,Q9NPF0,P41440,Q9H223,Q567U6,Q9BRK5,Q15075,Q15012,P51809,Q86YV9,Q99523,P31751,Q969Q5,O95219,O75955,Q9NWW5,Q6ZVM7,O60826 57 +Presynaptic cytoskeleton 0.6915502798296487 1.0658422303536514 0.2864949671826751 1.0 0.6839879844780096 3 P07196 1 +Leading edge membrane 0.3696886768972544 1.0640527610216488 0.2873047989029018 1.0 0.6841304872048211 47 P23396,Q06481,O75787,Q14168,Q01082,P31751,Q9BZG1,P78536,P09493 9 +Organelle inner membrane 0.3570151110790874 1.048165141548709 0.2945625278198986 1.0 0.6959612056262892 287 P22830,Q99720,O96008,O43772,Q567V2,Q13505,Q9BRT2,O75027,Q9HC21,O60313,Q9BQT8,O95831,P00403,P03886,P20674,Q16891,Q8WUK0,P00846,Q9Y4W6,Q96CU9,Q9BT17,O75380,Q14728,Q99595,Q9Y619,Q9Y6C9,P82912,O95563,Q9UH99,O95168,O43676,Q10713,Q5T9A4,Q9H061,Q6DKK2,Q9Y3D3,Q9H2D1,Q9H3K2,Q9NQ50,Q9NVA1,P23786,Q69YU5,Q9Y2U8,Q03252,O75431,O75964,Q9Y2R0,Q9NRA0,Q9H4I9,P25705,O75844,Q8IYU8,Q9BSK2,Q86VD7,P39210,Q7KZN9,Q70HW3,Q9UBX3,Q9NWR8,O75251,Q9BPX6,P50336,P22695,P20700,Q13423,Q9BYD3,Q9BRJ2,Q9Y6N5,P49748,Q14739,Q15070,Q9BUB7,Q5SNT2,P23396,Q9H300,Q9NX63,O75306 77 +Sperm connecting piece 0.6127437517165553 1.0348243790193694 0.3007509354673354 1.0 0.7022916025917043 2 P47756 1 +Ficolin 1 rich granule 0.3447454643833069 1.0330007645870178 0.3016035408489912 1.0 0.7022916025917043 90 P16278,O00231,P42785,P20618,P14174,Q93050,P12956,P10253,Q99436 9 +Mcrd mediated mrna stability complex 0.6607012114338844 1.0277569618718756 0.3040641657961931 1.0 0.705614552687349 4 O60506 1 +Chromosome centromeric region 0.3372947852153137 1.021353091192144 0.3070871812636113 1.0 0.7072013387971927 110 Q8NBT2,Q96EE3,Q9HD42,Q8IWS0,Q6P1K2,Q8N3U4,Q8WVM7,Q9NTJ3,P50748,Q9Y6D9,Q14683,Q9NTI5,Q14807,O60566,Q96JM3,Q9H3R5,Q8IY18,P12270,P57740,Q14203,O75935,Q9NXR1,Q15021,Q96DY7,Q9UEE9,P48729,Q8NFH4,Q13362,Q9NZZ3,P55735,Q9NRZ9,Q96EA4,Q9Y448,Q29RF7,Q9UFC0,Q06787,Q9UQE7,Q53HL2,Q96IY1,Q96SB8,Q2NKX8,Q9BS16 42 +Intrinsic component of postsynaptic density membrane 0.6285974388762781 1.0200464141773358 0.307706448697588 1.0 0.7072013387971927 5 Q9BQT9 1 +Peptidase complex 0.3503407627327342 1.0197443848363656 0.3078497055948306 1.0 0.7072013387971927 63 O00231,P28070,P28074,P20618,P49721,P28072,Q99436,Q9UPT9,P60900 9 +Sarcolemma 0.417238870090158 1.0111821306173487 0.3119292667698183 1.0 0.7111987282351859 27 P11166,Q9H9S5,O75955,P41440,Q92542,P46939 6 +Spectrin 0.6557946715412009 1.0084778427631471 0.3132251195032172 1.0 0.7123723416133019 4 Q13813 1 +Perikaryon 0.4242561595559975 1.003829259350216 0.3154609186072652 1.0 0.7126975457969825 24 O75592,P05067,Q8N3R9 3 +Endosome membrane 0.3083293851434541 1.0032866794628916 0.3157225612675516 1.0 0.7126975457969825 152 Q14108,O15118,Q9HD42,Q9HC07,P30511,Q96PE3,Q8TCT8,Q99805,Q9Y5X2,P11717,Q8N4V1,P10321,Q9UH99,Q06481,Q9Y487,P02786,Q07960,O75787,Q96L92,Q9BXS4,P42892,Q92542,Q14457,O15127,Q8IV08,O00461,P51790,Q93050,P61020,P04439,Q9NPF0,O15400,Q9H223,Q15075,Q15012,P51809,Q86YV9,Q99523,O95219 39 +Cis golgi network 0.4291776510700985 1.0014558639098057 0.3166064678391818 1.0 0.7126975457969825 20 Q92538,Q08379,O00461,Q96JB2,Q86VS8,Q9NPR9,P30533,Q8TBA6,Q9UNK9,P24390 10 +Pseudopodium 0.5419552674673158 0.9989981092002916 0.3177956072348884 1.0 0.7126975457969825 8 P17655,P12814,O43707,P51809 4 +Myelin sheath 0.4775746354471495 0.9984588495831834 0.3180569091440481 1.0 0.7126975457969825 14 Q9NR77 1 +Intrinsic component of endoplasmic reticulum membrane 0.3502698907156829 0.993969423338654 0.3202377537737306 1.0 0.7158255672589273 60 Q9Y282,Q86XL3,Q8N4V1,P10321,Q9P2E9,Q86UP2,O75844,P30511,Q15629,Q8TB61,O75298,Q99442,Q8TCT8,Q9UBM7,Q969N2,Q5H8A4 16 +Gamma tubulin complex 0.6478959398846019 0.9775222224702228 0.3283106815764658 1.0 0.721821003002427 4 Q96CW5 1 +Mitochondria associated endoplasmic reticulum membrane 0.495065220179549 0.9745956888804288 0.3297608529462152 1.0 0.721821003002427 11 Q96N66,O43865 2 +Axon hillock 0.5973633617138082 0.9674472798890312 0.3333204842652502 1.0 0.7225501346900743 2 O14965 1 +Adherens junction 0.3568658594941819 0.9666063291301042 0.3337408694227681 1.0 0.7225501346900743 48 P35579,P26038,P41440,Q96TA1,Q8N3R9,O75955,O00192,Q9UQB8 8 +Nucleoid 0.3810273248459352 0.9638319986094686 0.3351301611555937 1.0 0.7225501346900743 35 P21796,P49748,P45880,O00411,Q9BRT2,Q96RR1,P29372 7 +Microvillus membrane 0.5826754469741499 0.9573389321784804 0.338396210810731 1.0 0.7278710949513837 6 P15311,P26038,P35222,Q01650 4 +Photoreceptor inner segment 0.5316174703918902 0.9514281844358764 0.3413870585570029 1.0 0.7280388969242958 8 P11166,Q15555,Q9BV73,Q96RK4 4 +Annulate lamellae 0.6115194938616523 0.9508759001390864 0.3416673770653493 1.0 0.7280388969242958 5 Q8TD16 1 +Microtubule organizing center 0.3367966362366534 0.938212959605787 0.3481349796480519 1.0 0.7373564095746733 235 Q13045,Q9Y496,Q9HD42,Q96C92,Q8TD16,Q86SX3,O75419,Q9H6D7,Q12834,Q9Y366,Q9Y6D9,Q13432,O60566,O75330,Q96CW5,P28070,P28074,P53985,Q8IUD2,Q14203,O75116,O75935,Q96ED9,O43805,Q9H981,P55081,Q6DKK2,P33176,P48729,Q9NZM3,O15078,Q8WXW3,Q13464,Q5VU43,Q96EA4,Q9Y448,Q8N1F7,P41440,Q9UFC0,Q15051,Q15555,P08670,Q9Y5Y2,O94927,Q96CS2,Q6IN85,Q5M775,O95684,Q9BSJ2,O75955,Q96RK4,Q9UPN4,A0AVF1 53 +Aryl hydrocarbon receptor complex 0.5904971161768675 0.9375697095667436 0.3484655839108379 1.0 0.7373564095746733 2 O00170 1 +Dendritic tree 0.3244415365263646 0.9346941175731645 0.3499459592879652 1.0 0.73877480294126 120 P51114,Q9BQT9,Q13136,Q7L0J3,Q9Y366,Q9UQB8,P05067,O75787,Q15375,Q14457,P33176,P12814,P50897,Q13641,Q14168,Q7L576,P11274,P17655,Q9H2U1,P23246 20 +Endoplasmic reticulum plasma membrane contact site 0.6543956043956055 0.9223105619901752 0.3563666063341455 1.0 0.7471410229350361 3 Q9NTJ5,O14523 2 +Plasma membrane region 0.3299117851518129 0.9170543167467372 0.3591141780660687 1.0 0.7511746110005841 218 Q99720,Q8WTV0,Q9BQT9,Q01650,O00291,Q9UQB8,P05067,P46939,P35579,P11166,Q06481,Q9BY67,P02786,P53985,O75787,O75251,Q15375,O75935,Q6P4Q7,P30825,O43865,Q9BZG1,Q92542,O14936,P23396,P55011,Q9NZM3,Q96RU3,P51790,Q9Y4G8,Q14168,P09493,P78536,P41440,Q9Y6M7,P35580,Q9NWH9,Q99523,Q01082,P15291,P57105,P31751,O75955 43 +Recycling endosome 0.3550101826319735 0.9039198370463843 0.366037909647293 1.0 0.7569763573658305 46 P10321,O15127,P02786,Q96C92,P30511,Q96PE3,P51790,O14773,P04439,Q9H223,P05067 11 +Cluster of actin based cell projections 0.3700681199304568 0.8832718591671102 0.3770894043852917 1.0 0.7728214310098562 36 P35579,P12814,Q9UEY8,Q7Z406,P15291,P41440,Q9Y6M7 7 +Synaptic membrane 0.3412877237997143 0.8700265373353341 0.3842859020166238 1.0 0.784046404114454 53 Q99720,Q9NZM3,Q9BQT9,O14936,O75787,O75251,Q15375,Q14168,P57105,O00291,Q9UQB8,Q92542,P46939 13 +Filopodium tip 0.5586605557634334 0.8571251718365743 0.3913757111115847 1.0 0.7945294603051899 6 Q9H4L5 1 +Core mediator complex 0.5103491519582534 0.8543116581102815 0.3929323293849993 1.0 0.7945294603051899 8 Q71SY5 1 +Anaphase promoting complex 0.4704163901333706 0.8479810134632566 0.3964485446969401 1.0 0.7952464288262239 11 O60566,Q16763,Q12834 3 +Sumo ligase complex 0.5841849177423771 0.8414466455967787 0.4000977631519951 1.0 0.7984445514105459 5 Q8IY18 1 +Rdna heterochromatin 0.612190082218255 0.8392196449586573 0.4013460653218503 1.0 0.7991869248330296 4 Q9UIF9 1 +Intrinsic component of mitochondrial membrane 0.3371917179546141 0.8343415507304044 0.4040885438456032 1.0 0.8026268549129539 55 O95563,Q16891,Q9NWR8,Q9BUB7,O96008,Q9H4I9,Q15070,P57105,Q13505,O75431,Q9BPX6,Q9HC21,Q9Y2R0,Q9GZY8,P50336,Q9NX63 16 +Tertiary granule 0.355206755822666 0.8330195196321873 0.4048337206797794 1.0 0.8026268549129539 42 P42785,O75787,Q93050,P10253,Q7L576,Q13813 6 +Dna replication factor c complex 0.5506523734417444 0.8240500562884178 0.4099111164948075 1.0 0.8078554418159091 6 P41440 1 +Brush border 0.3775000105404823 0.8236677552249839 0.4101283657464538 1.0 0.8078554418159091 31 P35579,Q13045,Q14728,P12814,Q7Z406,P15291,P41440,Q9UEY8 8 +Intrinsic component of mitochondrial inner membrane 0.3618963624337306 0.815724002094284 0.4146580080197162 1.0 0.814325358493927 36 O95563,Q16891,Q9H3K2,Q9NWR8,Q9H4I9,Q99595,Q15070,Q9Y4W6,Q13505,Q6P4A7,O75431,Q9HC21,Q9Y2R0,P50336,Q9NX63 15 +Box c d rnp complex 0.5483987536797368 0.8147790677871859 0.4151987847584166 1.0 0.814325358493927 6 Q9Y2X3,P55769 2 +Intermediate filament cytoskeleton 0.3629478022882275 0.8073568535149522 0.4194609174875618 1.0 0.8147454440937094 34 P07197,P20700,P48729,P08670,Q03252,P02545,O75298,P07196 8 +Scar complex 0.5464143577322698 0.8066298352812622 0.4198797793026791 1.0 0.8147454440937094 6 Q7L576,Q96F07 2 +9plus0 non motile cilium 0.4212899254285345 0.797098177899058 0.4253940145093942 1.0 0.8203663432101792 16 Q9Y366,Q15051,Q15555,O15078 4 +Intrinsic component of postsynaptic specialization membrane 0.5440549839742561 0.7969585786766413 0.425475088090367 1.0 0.8203663432101792 6 Q9BQT9,Q15375 2 +Golgi membrane 0.3051370178929211 0.7925441239487485 0.4280434744216115 1.0 0.8215897364920078 174 Q92538,Q14108,Q92896,Q9BQT9,Q9HC07,Q8IZA0,P30511,O60476,Q9Y5Z9,P11717,P11166,Q8N4V1,P10321,Q8NCH0,Q96L58,Q08379,Q10472,Q15392,Q8TB61,Q8IUD2,Q9BXS4,P24390,Q8NDZ4,Q9Y282,O60499,Q8IV08,O00461,Q16739,Q13464,Q96JB2,O43505,P51790,Q9Y678,Q9H9S5,O43752,O60512,P78536,Q8NBN3,Q5SRI9,Q96CN9,P35606,O15260,P15291,Q8TBA6,Q9H3P7 45 +Blood microparticle 0.3967308659763376 0.7842336427487304 0.4329030278958168 1.0 0.8260496386920589 19 P11166,P27105,Q08380,P26038,P38435,P02786,P05198,Q5TA45,P04062 9 +Spindle pole 0.3244873215138787 0.7693291368318464 0.4416979444503131 1.0 0.8374813416604688 66 Q13432,Q9UQE7,Q96CW5,Q08379,Q9Y5Y2,Q8WVM7,Q14203,P52732,Q96CS2,Q96EA4,Q9Y448,Q9Y6A5,Q9NXR1,Q12834,Q9BSJ2,O43663,Q9Y6D9,Q5SNT2 18 +Actin filament bundle 0.3698599730041432 0.7655460834594003 0.4439464361001519 1.0 0.8375963503165103 31 P35579,P12814,P35580,Q7Z406,O43707,P09493,P67936 7 +Cdc73 paf1 complex 0.56465226934917 0.7645931446507545 0.4445138525802532 1.0 0.8375963503165103 5 Q92541,Q8N7H5 2 +Platelet dense granule 0.5907920330184935 0.7580825726034457 0.4484015519534094 1.0 0.8431798255288854 4 Q08380,Q92520 2 +Site of polarized growth 0.3297152803470948 0.7545947070837183 0.4504922004672573 1.0 0.8453437825775713 52 Q99720,P05067 2 +Golgi cisterna membrane 0.3825522738735682 0.7438379655139118 0.4569745086886063 1.0 0.8484727371167824 26 Q8WVQ1,Q08379,O00461,Q96L58,Q10472,Q99523,P15291,O60512,Q8NBN3 9 +Specific granule 0.3500816054504684 0.7376562994671575 0.4607233341988075 1.0 0.8505661554439524 38 Q8WVQ1,O15078,Q07065,P30519,Q8N2G8,Q7L576,Q13813 7 +Ruffle membrane 0.3606786981178391 0.7242441411557237 0.4689158634878416 1.0 0.858267749461132 32 P23396,Q06481,P31751,Q9BZG1,P78536,P09493 6 +Vesicle membrane 0.3404612791101569 0.7229268933493835 0.4697248000155596 1.0 0.858267749461132 301 Q14108,P42785,O15118,Q8WTV0,P84095,Q9HD42,Q9HC07,P30511,Q96PE3,P30519,O43493,Q5KU26,Q7L0J3,P10253,O00291,Q8TCT8,Q99805,Q9Y5X2,P11717,Q8N4V1,P20645,Q9UH99,Q06481,Q9UIQ6,Q9Y487,P02786,Q07960,Q07065,O75787,Q9BXS4,P42892,Q9BZG1,O75592,Q92542,Q14457,Q8NDZ4,P55011,O60499,P07602,Q8IV08,O15127,O00461,P55735,P51790,Q93050,O43752,Q9NPF0,Q9H223,Q15075,Q15012,P51809,Q13555,Q9Y5X1,O15260,P35606,Q15437,Q86YV9,Q99523,P15291,O95219,Q9NQX7 61 +Nucleotide activated protein kinase complex 0.5786889214778735 0.7129570795319821 0.4758723166567975 1.0 0.8628142202604361 4 P54619 1 +Neuron projection 0.326250584357703 0.7113194729215125 0.4768862872683792 1.0 0.8629370912475433 246 Q99720,Q9Y496,P51114,Q9BQT9,Q96N67,Q13136,Q7L0J3,Q8N3R9,Q9Y366,Q9UQB8,P05067,O60313,P51991,Q9BY67,Q7Z406,P80404,O75787,Q14203,O75251,Q15375,O75592,Q14457,P33176,P12814,P55011,O15078,P50897,O43707,Q13641,Q9Y4G8,Q14168,Q96F07,P51790,Q7L576,P11274,Q9Y6M7,P07197,Q15051,Q15555,Q15075,Q96RK4,P51809,P08670,Q13555,P17655,Q01082,P57105,P10586,Q9H2U1,P07196,P23246 51 +Spindle microtubule 0.3435144641447106 0.70474979483559 0.4809659571055094 1.0 0.8651695323081352 40 Q96CW5,Q9Y496,Q9HD42,P52732,Q96CS2,Q9H6D7,O43663 7 +Endoplasmic reticulum exit site 0.3831035084916099 0.6997169816709256 0.4841040691258205 1.0 0.8673927525397805 20 Q15437,Q9Y6B6,Q92734,Q9HCU5,P04439,Q969M3 6 +Proton transporting atp synthase complex 0.4303534087171168 0.6899371909981783 0.4902336864815357 1.0 0.8742164399475404 13 P00846,O75964 2 +Microtubule minus end 0.5909983705718853 0.6860123538763484 0.4927053181283287 1.0 0.8742164399475404 3 Q9P1Y5 1 +Condensed chromosome centromeric region 0.3143284373728989 0.6695433221286362 0.50314895511855 1.0 0.875451885411568 85 Q8NBT2,Q96EE3,Q9HD42,Q8IWS0,Q6P1K2,P50748,Q9Y6D9,Q14683,Q14807,O60566,Q96JM3,Q9H3R5,P12270,P57740,Q14203,O75935,Q9NXR1,Q15021,Q96DY7,P48729,Q8NFH4,Q9NZZ3,P55735,Q96EA4,Q9Y448,Q9UFC0,Q96IY1,Q2NKX8,Q9BS16 29 +Intraciliary transport particle b 0.5847585711896301 0.6636389292920949 0.5069214350736624 1.0 0.8755915696726896 3 Q9Y366 1 +Intraciliary transport particle 0.5847585711896301 0.6636389292920949 0.5069214350736624 1.0 0.8755915696726896 3 Q9Y366 1 +Sarcoplasmic reticulum membrane 0.4333770820525109 0.6451356328797875 0.5188392941105753 1.0 0.8873614728216824 10 Q13555,P16615 2 +Condensin complex 0.4773603724598747 0.6446240604869592 0.5191708388425114 1.0 0.8873614728216824 7 O95347,Q15003,Q15021,Q9NTJ3 4 +Copi vesicle coat 0.4296938964694856 0.6440029917789106 0.5195734939548009 1.0 0.8873614728216824 11 P35606,Q8NDZ4 2 +Chromosome passenger complex 0.557026381387407 0.6338846374714421 0.5261561120742355 1.0 0.8875101781350789 4 O14965,Q53HL2 2 +Lateral plasma membrane 0.370043165791833 0.6286317579723559 0.5295901640636318 1.0 0.8875101781350789 23 P53985 1 +Clathrin coated vesicle membrane 0.3578550596374818 0.6282974009088108 0.5298091339587621 1.0 0.8875101781350789 29 P11717,Q14108,P20645,P02786,O43493,O00291 6 +Spindle 0.2907473232065687 0.6119020413281658 0.5406025709579472 1.0 0.8970734630832778 167 Q13123,O15344,P06493,Q9Y496,Q9HD42,Q8N3U4,Q8WVM7,Q9H6D7,Q12834,Q9Y6D9,P05067,Q13432,P35579,O60566,O75330,Q96CW5,Q08379,P12270,Q14203,O75935,Q9NXR1,P29372,Q5SNT2,P23396,P48729,Q9NZZ3,Q9UJX3,P52732,Q96EA4,Q9Y448,O95239,P35222,P31749,Q15691,Q15051,Q15555,Q9UQE7,Q9Y5Y2,O94927,Q96CS2,Q9Y6A5,Q9HC35,O43663,Q9BSJ2 44 +B wich complex 0.4689033041530202 0.6098187433258857 0.541981883946147 1.0 0.8970734630832778 7 Q9NY93,Q9UIG0 2 +Microbody membrane 0.3484357315014868 0.6053969574373794 0.5449152721696049 1.0 0.9002947974976081 31 O00116,Q9UKU0,Q9NR77,O14678,P39210 5 +Intrinsic component of presynaptic membrane 0.4909806861219161 0.5860810500829238 0.5578210500669587 1.0 0.9007119020968303 6 P19022,Q92542 2 +Nuclear lamina 0.4906727528017404 0.5849040832356628 0.5586122128782822 1.0 0.9007119020968303 6 P02545,P20700 2 +Caspase complex 0.489211087900902 0.5793262588486054 0.5623690505534396 1.0 0.9007119020968303 6 Q969N2 1 +Cortical endoplasmic reticulum 0.5415924387543076 0.579113502020644 0.5625125901127608 1.0 0.9007119020968303 4 O14523 1 +Spindle midzone 0.3621640915104026 0.5730457864430435 0.5666136929902004 1.0 0.9007119020968303 22 Q15555,O43663,P05067 3 +Mpp7 dlg1 lin7 complex 0.501785223839595 0.5710177747307613 0.5679875940935981 1.0 0.9007119020968303 2 Q13112 1 +Non motile cilium 0.3622998745457754 0.5704910160657953 0.5683447137337239 1.0 0.9007119020968303 21 Q9Y366,Q15051,Q15555,O15078 4 +Cilium 0.3044999613076897 0.5702716185488207 0.5684934874476197 1.0 0.9007119020968303 105 Q9Y496,Q96C92,Q86SX3,Q9Y366,P05067,Q00796,P28070,A6NIH7,Q14203,Q9BZG1,O43805,P33176,O14936,O15078,Q15051,Q9NUQ9,Q15555,Q9Y5Y2,Q9UPN4,A0AVF1 20 +Chromatoid body 0.5006866245536864 0.5668061078638225 0.5708459204078595 1.0 0.9007119020968303 2 Q08J23 1 +Calcium channel complex 0.4163797876582925 0.5651011403020425 0.5720049729506593 1.0 0.9009819263057018 10 Q9H4I9,Q8IYU8,Q9NWR8 3 +Distal axon 0.3073869331933642 0.5612846596897813 0.5746034975025813 1.0 0.9026965800213532 62 Q99720,Q7Z406,Q13641,P07196,Q7L576,P05067 6 +Recycling endosome membrane 0.3577561327934871 0.5545464270053109 0.5792049414009837 1.0 0.9045118262974264 24 P10321,O15127,P02786,P30511,Q96PE3,Q9H223 6 +Condensed chromosome 0.2961497035299869 0.5383889865389148 0.5903085282358684 1.0 0.9117112791175572 119 Q8NBT2,Q9UEY8,Q96EE3,Q92878,Q8IWS0,Q9HD42,Q6P1K2,Q8N3U4,Q8WVM7,O95347,P50748,Q9Y6D9,Q14683,Q14807,O60566,Q96JM3,Q9H3R5,Q8IY18,P12270,P57740,Q14203,O75935,Q9NXR1,Q15021,Q96DY7,Q9UEE9,P48729,Q8NFH4,Q9NZZ3,P55735,Q96EA4,Q9Y448,Q9UFC0,Q9UQE7,Q9BYG3,Q96IY1,Q2NKX8,P26583,Q9BS16,Q9UIG0 40 +Axolemma 0.5474036207215348 0.53438087981251 0.5930780447575925 1.0 0.9117112791175572 3 Q01082 1 +Ikappab kinase complex 0.5468284243057047 0.5324618352659898 0.594406167927781 1.0 0.9117112791175572 3 Q8IUD2 1 +Beta catenin destruction complex 0.4766095288200496 0.53187635476387 0.5948116349505992 1.0 0.9117112791175572 6 P48729 1 +Outer kinetochore 0.5425547502623542 0.5182792769290308 0.6042634294358677 1.0 0.9174051280484898 3 Q96EA4 1 +Cell cortex 0.2986924776000244 0.5127647976668775 0.6081158568920633 1.0 0.9174051280484898 109 P84095,P46939,P35579,P11166,Q14203,P67936,Q13813,P12814,Q96RU3,O43707,O14523,P41440,P35580,P17655,Q9Y5X1,Q01082,P31751,Q9NS86,O75955,Q9P0K7 20 +Kinesin complex 0.3787904051241224 0.505587038141817 0.613146582803265 1.0 0.9174051280484898 15 Q9Y496,Q07866,Q02241,P52732,Q9NXR1,Q14807,P33176 7 +Neuron projection cytoplasm 0.3245048823231885 0.5051718202345399 0.6134381609102779 1.0 0.9174051280484898 34 Q14168,Q9UQB8,P07196,P23246,P33176 5 +Mcm complex 0.4693010950786808 0.504919649999497 0.6136152720499768 1.0 0.9174051280484898 6 Q14566 1 +Mitotic spindle astral microtubule 0.5376249577947494 0.5020896076452961 0.6156044900969841 1.0 0.918872823188952 3 Q15691 1 +Transcription preinitiation complex 0.5185490519373598 0.5002561715325925 0.6168947107767353 1.0 0.9192940788045468 4 P13984,Q00403,P19447 3 +Inner mitochondrial membrane protein complex 0.2999987206517069 0.4973899406615025 0.6189140978794996 1.0 0.9202329396449698 90 P03886,Q9BPX6,Q9NWR8,O43676,P00846,Q9H4I9,O75251,P25705,Q13505,Q8IYU8,O75431,O75964,O75380,Q96CU9 14 +Mediator complex 0.3898301985824478 0.4852662052055074 0.627487524595812 1.0 0.9275018191756572 13 Q9NVC6,Q9NYF8,Q9NPJ6,Q71SY5,Q9Y2W1 5 +Lamin filament 0.531415917282391 0.4819687088072246 0.6298281751170167 1.0 0.9276411516656726 3 P02545 1 +Intrinsic component of golgi membrane 0.3889160910851506 0.4808357508336067 0.6306332390709617 1.0 0.9276411516656726 13 Q9Y282,O43505,Q8N2H4,Q8TB61,Q9Y5Z9 5 +Messenger ribonucleoprotein complex 0.5094263679004132 0.4701408084599632 0.6382544201984366 1.0 0.9298530850175306 4 Q06787,P51991 2 +Pronucleus 0.4580541363177719 0.4643249534652114 0.6424149485381647 1.0 0.9336041754507906 6 P11166,Q15910,Q5UIP0 3 +Microbody 0.2966981086379738 0.4634061510512917 0.6430732704849711 1.0 0.9336041754507906 64 O00116,Q9NR77,Q9UKU0,P08670,O14678,Q96CN7,P39210,A3KMH1,O15254,P48735,Q9GZY8 11 +Spindle pole centrosome 0.405992511427551 0.4595610018633421 0.6458313566467211 1.0 0.934917773431444 9 P50402,Q9Y5Y2,O14965,Q9NXR1 4 +Actin cytoskeleton 0.2701858351053528 0.4575620236631369 0.6472671324541603 1.0 0.9355112912808148 144 Q13045,Q4VCS5,P06753,Q9Y5S2,Q9UQB8,P46939,P35579,P11166,P35221,Q7Z406,O75935,P67936,Q13813,O14936,P12814,Q9BTX1,O43707,P09493,P78536,Q9BX67,P41440,P35580,P17655,Q9Y5X1,Q6WCQ1,Q5M775,Q01082,Q9NS86,O75955 29 +External encapsulating structure 0.3149008530867257 0.4472578479076006 0.654688898052096 1.0 0.9402775984622228 37 P20073,Q13043,P07942,Q08380,P07602,Q92896,Q96RT1,P84157,Q5KU26,P49257,P19022,P55081,O14936 13 +Nadh dehydrogenase complex 0.3277409147541876 0.437388575872716 0.6618295677448705 1.0 0.9417336383723026 30 P03886,O43676,Q96CU9,O75380 4 +Cd40 receptor complex 0.5156588869140997 0.4323487206702014 0.6654879819291879 1.0 0.9424301855891606 3 Q9NR28 1 +Ragulator complex 0.4586652018676082 0.4147458997902136 0.6783279274735989 1.0 0.952892524206276 2 Q9Y2Q5 1 +Transport vesicle membrane 0.2929258349358287 0.4091542799462376 0.6824264442561532 1.0 0.9529522834828996 51 O60499,P30511,Q15437,Q7L0J3,O75592 5 +Organelle membrane contact site 0.3354125703609438 0.4061300367015734 0.6846470569768277 1.0 0.9529522834828996 20 Q96N66,O14523,O43865 3 +Endoplasmic reticulum tubular network 0.3583241455347153 0.4004217358651042 0.6888459175350383 1.0 0.9529522834828996 15 Q9H6H4,Q9NP72,Q6NUK4,P50402,P61026,Q00765,Q9NQC3,Q14974,Q6DD88,Q12797,O14523,Q8NHH9,Q15042,Q9BRK0 14 +Endoplasmic reticulum tubular network membrane 0.5041208791208808 0.3974311276033451 0.6910495651270538 1.0 0.9529522834828996 3 Q8NHH9,Q6DD88 2 +Proton transporting atp synthase complex coupling factor f o 0.4004913463284247 0.3907471217410843 0.6959841642771076 1.0 0.9529522834828996 8 P00846 1 +Prp19 complex 0.3744493392070647 0.3880274072513251 0.6979957514984396 1.0 0.9529522834828996 11 P11142,Q9BZJ0,Q99459,O75934,Q9NW64,Q9ULR0,Q9UMS4,Q9P013,Q8WYA6,Q9HCS7 10 +Origin recognition complex 0.4076130149613075 0.3753473179659312 0.7074021795706646 1.0 0.9580463222750348 7 Q9Y619,Q9UFC0 2 +Dna repair complex 0.3376208986602502 0.3730915100905419 0.7090803372101409 1.0 0.9580463222750348 17 P12956 1 +Specific granule lumen 0.3439991011251234 0.3656440218741947 0.7146307216939167 1.0 0.9605209540613486 16 Q7L576,Q13813,O15078,Q8N2G8 4 +Rough endoplasmic reticulum 0.3003436039276942 0.3388102412602965 0.7347526857185169 1.0 0.9697459469975216 37 Q9UQB8,Q9H9S5,P05067,Q07065 4 +Paraspeckles 0.4200658524604502 0.3365816057040563 0.7364323244603335 1.0 0.9702001961592824 6 P23246 1 +Endoplasmic reticulum 0.3119191284407245 0.3324525599988117 0.7395475560412836 1.0 0.9702001961592824 556 Q99720,Q86XL3,Q01105,P27544,P07099,Q15629,P30519,Q7L0J3,Q99442,O75503,Q9UQB8,Q9UMX5,P05067,A2RRP1,P10321,Q06481,Q10472,Q15392,Q8TB61,Q96GC9,O43865,Q5H8A4,P10619,P24390,O94874,P20073,Q02818,Q16850,Q8IV08,Q8NBJ4,O60858,P80303,Q9BRK5,Q9H4L5,O00584,Q13555,O15260,Q15437,Q99523,Q9BTY2,O43681,Q9NUN5,P07942,P84095,P30511,O43493,Q8TCT8,Q96G23,Q8N4V1,P16615,Q07065,Q70UQ0,O14678,Q9HD20,Q9Y6K0,Q14457,Q9Y282,O15173,P55735,Q8N0U8,P78536,Q8IXB1,Q9NRA0,Q9NZ08,Q9NWW5,O95456,O75844,Q14108,O15118,Q9BQT9,O60476,Q9Y5Z9,Q9UBM7,Q14257,Q86UP2,O75787,O75718,Q9H2J4,Q969N2,Q92542,Q13641,Q9H9S5,P04843,Q969M3,Q96N66,P61916,Q9Y680,Q53T59,Q96HY6,Q9P2E9,Q8N2G8,O75298,Q9UKU0,Q8WVQ1,Q14739,Q6PIU2,Q6ZXV5,P23396,Q8N2F6,Q8IY95,P30533,O14523,Q9NPF0,Q9H223,P51809,P17655,P35606,Q86YV9,Q8NAT1,Q96KC8,Q9NUQ7 111 +Coated vesicle membrane 0.281235287533255 0.3312046381581275 0.7404899170139556 1.0 0.9702001961592824 68 P11717,Q14108,P10321,P20645,P51809,P02786,P55735,P35606,P30511,O43493,Q15437,Q9Y678,O00291,P24390,Q8NDZ4 15 +Axon 0.2684786478307039 0.3090865897092076 0.7572556599404041 1.0 0.9808993410939092 135 Q99720,Q9Y496,Q96N67,Q13136,Q8N3R9,P05067,Q7Z406,O75787,O75592,P33176,P50897,Q13641,Q14168,Q7L576,P11274,P07197,Q15075,Q01082,P07196 19 +Mitotic spindle 0.2779779604705892 0.3039770636140808 0.7611453654123925 1.0 0.9810685731410388 74 Q13123,P06493,Q8N3U4,Q8WVM7,Q9H6D7,Q9Y6D9,Q08379,P12270,Q14203,P23396,P52732,Q9Y448,Q9UQE7,Q15051,Q15691,O94927,Q96CS2,Q9Y6A5,Q9HC35,O43663 20 +Smn complex 0.4071853905367034 0.2971006890769578 0.7663896383034332 1.0 0.981316962192374 6 Q8TEQ6,Q9NWZ8,Q9UHI6 3 +Chromocenter 0.4065607188815908 0.2952410850035618 0.7678097187464799 1.0 0.981316962192374 6 Q06787,P45973,Q53HL2 3 +Basement membrane 0.4063588758408077 0.2946413317255397 0.7682678848742928 1.0 0.981316962192374 6 P07942 1 +Cell body membrane 0.4650397713556483 0.2893365950358751 0.7723238105188333 1.0 0.9837420603256648 3 P55011 1 +Protein phosphatase 4 complex 0.4613014656455536 0.2799008633653504 0.7795535648175906 1.0 0.9888078596851776 3 Q6IN85 1 +Photoreceptor outer segment 0.3481226718327216 0.2758164668414904 0.7826890354182117 1.0 0.9914061115297348 10 Q15051,Q15555,Q9BV73,Q96RK4 4 +Stereocilium membrane 0.3996154902499277 0.2392219405561516 0.8109334903999856 1.0 1.0 2 Q9HBM0 1 +Immunological synapse 0.3288754909440364 0.2369364314861734 0.8127061063261287 1.0 1.0 14 P35579,Q13740,P15311,P20020,Q96L92,O15400 6 +Chitosome 0.3952210931062859 0.2283109396549648 0.8194045205193439 1.0 1.0 2 Q9NP58 1 +Filopodium membrane 0.4192161673990017 0.217344445455892 0.8279399223659205 1.0 1.0 4 Q8WXH0,P46939 2 +Extrinsic component of postsynaptic specialization membrane 0.3878055479263861 0.2106335096705935 0.8331732619497854 1.0 1.0 2 P52292 1 +Crd mediated mrna stability complex 0.3703934913105065 0.19706624899627 0.8437756948852642 1.0 1.0 6 O60506 1 +Nuclear periphery 0.2650413510914782 0.1645312927572141 0.8693129143482705 1.0 1.0 64 P20700,Q9UQE7,Q96FV9,Q15233,Q9HD42,P08670,Q8N3U4,Q8WVM7,P02545,Q13427,Q13573,Q8N1F7,P60900,O95239,Q5BKZ1,P23246,O14936 17 +Microtubule plus end 0.3136807580843564 0.1590063247820476 0.8736638907759517 1.0 1.0 12 Q9Y448,Q15555 2 +Gemini of coiled bodies 0.3538575362920513 0.1588698073542797 0.8737714487800015 1.0 1.0 6 Q8TEQ6,Q9NWZ8,Q9UHI6 3 +Copi coated vesicle membrane 0.3082798864016542 0.1569952723269051 0.8752485740360121 1.0 1.0 14 P35606,P24390,Q8NDZ4 3 +Mrna cleavage factor complex 0.3071334888996169 0.1528490335906062 0.8785173287997265 1.0 1.0 14 Q5KU26,Q92797 2 +Ciliary base 0.3298861666555771 0.1471224417511676 0.8830353766647294 1.0 1.0 7 Q9Y366 1 +Transcription export complex 2 0.3978021978021998 0.1470117619404513 0.8831227365086491 1.0 1.0 3 Q5JVF3,Q9NPA8 2 +Ficolin 1 rich granule lumen 0.260534630745696 0.143953855088092 0.8855369083100948 1.0 1.0 72 Q99436,P12956,P20618,P14174 4 +Meiotic spindle 0.3958791208791228 0.143831205264391 0.8856337608340441 1.0 1.0 3 O14965,Q9NQS7 2 +Contractile fiber 0.2624231553289091 0.1390771561882737 0.8893891794972928 1.0 1.0 61 P11166,P12814,Q14331,O43707,Q5VU43,Q01082,P06753,O75298,P09493,P67936,Q13049,P60900 12 +Dna replication preinitiation complex 0.3064550747217885 0.1358202256015425 0.8919634015073519 1.0 1.0 11 Q14566,Q9BRT9 2 +Secondary lysosome 0.3490799230980458 0.1336870380355171 0.893650055299499 1.0 1.0 2 P11279 1 +Autolysosome 0.3490799230980458 0.1336870380355171 0.893650055299499 1.0 1.0 2 P11279 1 +Platelet dense granule membrane 0.3490799230980457 0.1336870380355168 0.8936500552994993 1.0 1.0 2 O15439 1 +Phagophore assembly site 0.311402504024618 0.132899789376839 0.8942726334796736 1.0 1.0 9 Q5MNZ6,Q14457,Q96GC9 3 +Nuclear ubiquitin ligase complex 0.2965157318772773 0.1303209142106575 0.8963125340251756 1.0 1.0 15 O60566,Q16763,Q12834 3 +Pericentriolar material 0.3379686942786564 0.1263831189819592 0.899428664101801 1.0 1.0 6 Q96RK4 1 +Male pronucleus 0.3430376270255379 0.1240155383702721 0.9013029721986232 1.0 1.0 2 Q5UIP0 1 +Microtubule end 0.2977537677742237 0.1202059359428117 0.9043200156719922 1.0 1.0 14 Q9Y448,Q15555 2 +Chloride channel complex 0.3173203162536227 0.1198440611520371 0.9046066776979692 1.0 1.0 7 Q9H813 1 +Copi coated vesicle 0.2892929064910468 0.104876726293362 0.9164736268328748 1.0 1.0 15 P35606,P24390,Q8NDZ4 3 +Respirasome 0.2558963234672758 0.0975448142375747 0.9222937472732546 1.0 1.0 54 P03886,P22695,O43676,O75251,O75380,Q7KZN9,Q96CU9,Q6DKK2 8 +Npbaf complex 0.2967862865799484 0.0974568478068197 0.9223636015082708 1.0 1.0 9 Q12824,P51532,Q8WUB8 3 +Anchored component of synaptic vesicle membrane 0.3524115022895825 0.0972894555395737 0.9224965295370268 1.0 1.0 4 P61020 1 +Golgi associated vesicle membrane 0.2748110541757488 0.0917271845713463 0.9269147982738786 1.0 1.0 24 P35606,Q9Y678,Q8TCT8,P24390,Q8NDZ4 5 +Organelle subcompartment 0.3145272685665566 0.0853370547682991 0.9319934335183198 1.0 1.0 452 Q92538,Q99720,Q86XL3,P27544,P07099,Q15629,P30519,Q99442,P05067,A2RRP1,P10321,P20645,Q10472,Q15392,Q8TB61,Q96GC9,Q9NPR9,Q9BXS4,O43865,Q5H8A4,P24390,O94874,P20073,Q16850,Q8IV08,O00461,Q92604,Q96JB2,O60858,Q9Y678,O60512,P04439,Q9H4L5,Q13555,Q9Y5X1,O15260,Q15437,Q99523,P15291,Q9NUN5,Q4J6C6,P84095,P30511,O43493,Q8TCT8,Q96G23,P11717,Q8N4V1,P16615,Q07065,Q70UQ0,O14678,Q96ED9,Q9HD20,Q9Y6K0,O75592,Q14457,Q9Y282,O60499,O15127,P55735,Q8N0U8,Q8NBN3,Q9NX62,Q9NZ08,Q9NWW5,O75844,Q14108,Q9BQT9,Q9Y5Z9,Q9UBM7,Q96L58,Q86UP2,O75787,Q969N2,P04843,Q969M3,Q96N66,Q96CN9,Q8TBA6,Q96HY6,Q9P2E9,Q9HC07,O75298,Q9UKU0,Q8WVQ1,Q08379,Q14739,Q6PIU2,Q9BZG1,Q8N2F6,Q8IWJ2,O43752,O14523,P51809,P35606,Q8NAT1,Q96KC8 98 +Nbaf complex 0.2918844566712609 0.0805136207403374 0.9358287636198228 1.0 1.0 8 Q12824,O14497,Q969G3,P51532,Q96GM5,Q92922,Q8TAQ2 7 +Pigment granule 0.25474233047006 0.0777439021543039 0.9380317708963476 1.0 1.0 62 P11166,Q93050,O14773,O75955,P41440,Q92542,P04843 7 +Cul4a ring e3 ubiquitin ligase complex 0.3043120021971931 0.0761591434371714 0.9392924870579296 1.0 1.0 2 Q92990 1 +Tertiary granule membrane 0.2850445116599669 0.0739558572604329 0.9410455098272428 1.0 1.0 12 P10253,O75787 2 +Eukaryotic translation initiation factor 4f complex 0.2859265558736985 0.0699090180084191 0.9442660753603822 1.0 1.0 8 Q15056 1 +Extrinsic component of plasma membrane 0.2574850368953097 0.0694603086351461 0.9446232254331915 1.0 1.0 41 Q9H1P3,O00291,P35221,Q15334,Q00536,P40818,Q14980,P63000,Q9UBI6,P19022,P31749,P35222,P46940,Q06787,Q15075,Q96AC1,P52292,Q14344,Q9Y5X1 19 +Collagen containing extracellular matrix 0.261402772879714 0.0657901769054377 0.9475448769870464 1.0 1.0 32 P20073,Q13043,P07942,Q08380,P07602,Q96RT1,P84157,P49257,O14936 9 +Presynaptic active zone membrane 0.2955732746769482 0.0601423340588432 0.9520422732633976 1.0 1.0 6 Q9Y639,P20020,P27824,P19022,Q12846 5 +Protein complex involved in cell adhesion 0.3170161721127161 0.0585334295052712 0.9533237352378314 1.0 1.0 4 Q9BX67,P17301 2 +Extrinsic component of postsynaptic membrane 0.3118370689935938 0.0541716783160766 0.9567983849706424 1.0 1.0 4 O00291 1 +Polymeric cytoskeletal fiber 0.2654178606989171 0.0493991031800736 0.9606012428497532 1.0 1.0 196 Q4VCS5,O15344,P78371,Q9Y496,Q9HD42,Q16352,Q9H6D7,P02545,P06753,O75298,Q9UQB8,O60313,Q96CW5,Q08379,Q14203,Q96ED9,Q9NXR1,P67936,P29372,P33176,P20700,P48729,P12814,P52732,Q03252,Q9Y448,Q13330,P09493,Q9BX67,P07197,Q15555,P08670,O94927,Q96CS2,Q5M775,Q9BSJ2,O43663,P07196 38 +Eukaryotic translation initiation factor 2 complex 0.304204451772477 0.0483005608907996 0.9614767075510016 1.0 1.0 4 P05198,P41091,Q9BY44 3 +Intrinsic component of presynaptic active zone membrane 0.2954920285871384 0.0482829236303207 0.9614907636492132 1.0 1.0 5 P27824,P19022,Q9Y639,P20020 4 +Integral component of presynaptic active zone membrane 0.2954920285871384 0.0482829236303207 0.9614907636492132 1.0 1.0 5 P27824,P19022,Q9Y639,P20020 4 +Intrinsic component of mitochondrial outer membrane 0.2676371528342603 0.0377789929077841 0.9698638936445358 1.0 1.0 15 Q9GZY8 1 +Postsynaptic endosome 0.2826923076923098 0.0371329700596107 0.9703789838422714 1.0 1.0 3 Q86Y82,P20338 2 +Autophagosome 0.2505026925868874 0.0295243974802723 0.9764463610452928 1.0 1.0 35 Q9HD42,P19474,Q14457 3 +Protein phosphatase type 2a complex 0.2573894357850254 0.0293822412387431 0.9765597361285384 1.0 1.0 7 Q13362 1 +Endoplasmic reticulum golgi intermediate compartment 0.2480491712691871 0.0288943910396918 0.9769488190576538 1.0 1.0 60 Q92538,Q02818,Q9Y282,Q08379,Q10472,O15260,Q96GC9,P30533,Q8N3R9,P24390,P80303 11 +Granular component 0.2682055509755551 0.0285011039948733 0.9772624875275464 1.0 1.0 4 O75683,P22087,Q14684 3 +Wash complex 0.2657857346722759 0.0270948452442669 0.9783840861520512 1.0 1.0 5 Q12768,Q9Y3C0 2 +Preribosome small subunit precursor 0.265362358776529 0.0261162885681006 0.97916458509531 1.0 1.0 14 P56182,Q13895,Q86U38,P78316,Q9ULX3,Q2NL82,Q8IY81,Q14684,Q9BVS4,Q9BVI4,Q9NSI2,Q96GA3,P05386 13 +Transcription factor tfiiic complex 0.2592083562396973 0.0236817903079733 0.9811064311621288 1.0 1.0 5 Q9Y5Q9,Q9UKN8,Q12789,Q9Y5Q8 4 +Rna polymerase iii transcription regulator complex 0.2592083562396973 0.0236817903079733 0.9811064311621288 1.0 1.0 5 Q9Y5Q9,Q9UKN8,Q12789,Q9Y5Q8 4 +Actin filament 0.2490992872363664 0.0206196038724347 0.9835491021613034 1.0 1.0 38 P12814,Q5M775,P06753,P09493,P67936,Q9BX67 6 +Brca1 c complex 0.2352294586424961 0.0191849919447768 0.98469353009377 1.0 1.0 4 Q92878,O60934,P49959 3 +Supramolecular polymer 0.2806445593589005 0.0186372159648969 0.9851305139392116 1.0 1.0 244 Q4VCS5,O15344,P78371,Q9Y496,P51114,Q9HD42,Q9H6D7,P02545,P06753,O75298,Q9UQB8,P60900,P35579,P11166,Q96CW5,Q08379,Q7Z406,Q14203,Q96ED9,P67936,Q13049,P55081,P29372,P33176,P20700,P48729,P12814,P52732,Q03252,Q5VU43,O43707,Q9Y448,P09493,Q9BX67,P07197,P35580,Q15555,P08670,O94927,Q96CS2,Q14331,Q5M775,Q01082,Q9BSJ2,O43663,P07196 46 +Costamere 0.2449821281275868 0.0164135213738756 0.9869044927063346 1.0 1.0 6 Q14315,P51114,Q15149,P18206,Q12955 5 +Magnesium dependent protein serine threonine phosphatase complex 0.2551603515369983 0.0139404568535117 0.9888774849586836 1.0 1.0 11 Q6IN85,Q8TF05,Q13362 3 +Extrinsic component of synaptic membrane 0.2296265235837448 0.0128671370474171 0.989733793293279 1.0 1.0 5 O00291 1 +Golgi transport complex 0.23743377137263 0.0125641411163359 0.9899755295240996 1.0 1.0 6 Q96JB2 1 +Postsynapse 0.2444908375012755 0.0107258489809885 0.991442174784388 1.0 1.0 137 Q14012,Q99720,P51114,Q9BQT9,Q96PE3,O00291,Q9UQB8,P05067,P46939,Q9BY67,O75787,Q15375,P23396,P12814,P51790,Q14168,Q7L576,P11274,Q01082,P57105,P07196,Q9UEY8 22 diff --git a/msigdb_gocc/selections.json b/msigdb_gocc/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..277976eea0a127944540d44e4d32ca063be3b738 --- /dev/null +++ b/msigdb_gocc/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["90s preribosome", "9plus0 non motile cilium", "9plus2 motile cilium", "A band", "Acrosomal membrane", "Acrosomal vesicle", "Actin based cell projection", "Actin cytoskeleton", "Actin filament", "Actin filament bundle", "Actomyosin", "Adherens junction", "Aggresome", "Alpha dna polymerase primase complex", "Alveolar lamellar body", "Aminoacyl trna synthetase multienzyme complex", "Ampa glutamate receptor complex", "Amphisome", "Amphisome membrane", "Anaphase promoting complex", "Anchored component of membrane", "Anchored component of plasma membrane", "Anchored component of postsynaptic membrane", "Anchored component of synaptic membrane", "Anchored component of synaptic vesicle membrane", "Anchoring junction", "Annulate lamellae", "Ap 1 adaptor complex", "Ap 3 adaptor complex", "Ap type membrane coat adaptor complex", "Apical dendrite", "Apical junction complex", "Apical part of cell", "Apical plasma membrane", "Apicolateral plasma membrane", "Arp2 3 protein complex", "Aryl hydrocarbon receptor complex", "Aster", "Astrocyte end foot", "Astrocyte projection", "Atac complex", "Atp binding cassette abc transporter complex", "Atpase complex", "Atpase dependent transmembrane transport complex", "Autolysosome", "Autophagosome", "Autophagosome membrane", "Axolemma", "Axon", "Axon cytoplasm", "Axon hillock", "Axon initial segment", "Axonal growth cone", "Axonemal microtubule", "Azurophil granule", "Azurophil granule lumen", "Azurophil granule membrane", "B wich complex", "Barr body", "Basal cortex", "Basal dendrite", "Basal part of cell", "Basement membrane", "Basolateral plasma membrane", "Bbsome", "Bcl 2 family protein complex", "Beta catenin destruction complex", "Beta catenin tcf complex", "Bleb", "Bloc complex", "Blood microparticle", "Box c d rnp complex", "Box h aca rnp complex", "Box h aca snornp complex", "Box h aca telomerase rnp complex", "Brca1 a complex", "Brca1 c complex", "Brisc complex", "Brush border", "Brush border membrane", "Cajal body", "Calcineurin complex", "Calcium and calmodulin dependent protein kinase complex", "Calcium channel complex", "Camp dependent protein kinase complex", "Carboxy terminal domain protein kinase complex", "Caspase complex", "Catalytic complex", "Catalytic step 1 spliceosome", "Catalytic step 2 spliceosome", "Catenin complex", "Cation channel complex", "Cation transporting atpase complex", "Catsper complex", "Caveola", "Ccaat binding factor complex", "Ccr4 not complex", "Ccr4 not core complex", "Cd40 receptor complex", "Cd95 death inducing signaling complex", "Cdc73 paf1 complex", "Cell body", "Cell body membrane", "Cell cell contact zone", "Cell cell junction", "Cell cortex", "Cell cortex region", "Cell division site", "Cell leading edge", "Cell pole", "Cell projection membrane", "Cell substrate junction", "Cell surface", "Cell tip", "Cell trailing edge", "Central element", "Centriolar satellite", "Centriolar subdistal appendage", "Centriole", "Centrosome", "Cerebellar mossy fiber", "Chaperone complex", "Chaperonin containing t complex", "Chitosome", "Chloride channel complex", "Cholinergic synapse", "Chromaffin granule", "Chromaffin granule membrane", "Chromatin", "Chromatin silencing complex", "Chromatoid body", "Chromocenter", "Chromosomal region", "Chromosome", "Chromosome centromeric core domain", "Chromosome centromeric region", "Chromosome passenger complex", "Chromosome telomeric region", "Chromosome telomeric repeat region", "Chylomicron", "Cia complex", "Ciliary basal body", "Ciliary base", "Ciliary membrane", "Ciliary plasm", "Ciliary rootlet", "Ciliary tip", "Ciliary transition zone", "Cilium", "Cis golgi network", "Cis golgi network membrane", "Clathrin adaptor complex", "Clathrin coat", "Clathrin coat of coated pit", "Clathrin coat of endocytic vesicle", "Clathrin coated endocytic vesicle", "Clathrin coated endocytic vesicle membrane", "Clathrin coated pit", "Clathrin coated vesicle", "Clathrin coated vesicle membrane", "Clathrin complex", "Clathrin sculpted gamma aminobutyric acid transport vesicle", "Clathrin sculpted vesicle", "Clathrin vesicle coat", "Cleavage furrow", "Cluster of actin based cell projections", "Coated vesicle", "Coated vesicle membrane", "Cohesin complex", "Collagen containing extracellular matrix", "Collagen trimer", "Commitment complex", "Compact myelin", "Condensed chromosome", "Condensed chromosome centromeric region", "Condensed nuclear chromosome", "Condensin complex", "Contractile fiber", "Contractile ring", "Cop9 signalosome", "Copi coated vesicle", "Copi coated vesicle membrane", "Copi vesicle coat", "Copii coated er to golgi transport vesicle", "Copii vesicle coat", "Core mediator complex", "Cornified envelope", "Cortical actin cytoskeleton", "Cortical cytoskeleton", "Cortical endoplasmic reticulum", "Cortical granule", "Costamere", "Crd mediated mrna stability complex", "Ctf18 rfc like complex", "Cul2 ring ubiquitin ligase complex", "Cul3 ring ubiquitin ligase complex", "Cul4 ring e3 ubiquitin ligase complex", "Cul4a ring e3 ubiquitin ligase complex", "Cul4b ring e3 ubiquitin ligase complex", "Cul5 ring ubiquitin ligase complex", "Cullin ring ubiquitin ligase complex", "Cuticular plate", "Cyclin a2 cdk2 complex", "Cyclin cdk positive transcription elongation factor complex", "Cyclin dependent protein kinase holoenzyme complex", "Cytochrome complex", "Cytolytic granule", "Cytoplasmic dynein complex", "Cytoplasmic exosome rnase complex", "Cytoplasmic microtubule", "Cytoplasmic region", "Cytoplasmic side of endoplasmic reticulum membrane", "Cytoplasmic side of endosome membrane", "Cytoplasmic side of lysosomal membrane", "Cytoplasmic side of membrane", "Cytoplasmic stress granule", "Cytoplasmic ubiquitin ligase complex", "Cytoskeleton of presynaptic active zone", "Cytosolic large ribosomal subunit", "Cytosolic region", "Cytosolic ribosome", "Cytosolic small ribosomal subunit", "Death inducing signaling complex", "Dendrite cytoplasm", "Dendrite membrane", "Dendrite terminus", "Dendritic growth cone", "Dendritic shaft", "Dendritic spine head", "Dendritic spine membrane", "Dendritic tree", "Dense body", "Dense core granule", "Dentate gyrus mossy fiber", "Derlin 1 retrotranslocation complex", "Desmosome", "Dihydrolipoyl dehydrogenase complex", "Distal axon", "Dna packaging complex", "Dna polymerase complex", "Dna repair complex", "Dna replication factor c complex", "Dna replication preinitiation complex", "Dopaminergic synapse", "Dynactin complex", "Dynein axonemal particle", "Dynein complex", "Dystrophin associated glycoprotein complex", "Early endosome", "Early endosome lumen", "Early endosome membrane", "Early phagosome", "Ekc keops complex", "Elongator holoenzyme complex", "Elongin complex", "Emc complex", "Endocytic vesicle", "Endocytic vesicle lumen", "Endocytic vesicle membrane", "Endolysosome", "Endolysosome lumen", "Endolysosome membrane", "Endopeptidase complex", "Endoplasmic reticulum", "Endoplasmic reticulum chaperone complex", "Endoplasmic reticulum exit site", "Endoplasmic reticulum golgi intermediate compartment", "Endoplasmic reticulum golgi intermediate compartment membrane", "Endoplasmic reticulum lumen", "Endoplasmic reticulum palmitoyltransferase complex", "Endoplasmic reticulum plasma membrane contact site", "Endoplasmic reticulum protein containing complex", "Endoplasmic reticulum quality control compartment", "Endoplasmic reticulum tubular network", "Endoplasmic reticulum tubular network membrane", "Endoribonuclease complex", "Endosome", "Endosome lumen", "Endosome membrane", "Envelope", "Enzyme activator complex", "Epsilon dna polymerase complex", "Equatorial microtubule organizing center", "Er membrane insertion complex", "Er to golgi transport vesicle membrane", "Er ubiquitin ligase complex", "Esc e z complex", "Escrt complex", "Escrt i complex", "Escrt iii complex", "Euchromatin", "Eukaryotic translation initiation factor 2 complex", "Eukaryotic translation initiation factor 2b complex", "Eukaryotic translation initiation factor 3 complex", "Eukaryotic translation initiation factor 3 complex eif3m", "Eukaryotic translation initiation factor 4f complex", "Excitatory synapse", "Exocyst", "Exocytic vesicle", "Exon exon junction complex", "Exoribonuclease complex", "External encapsulating structure", "External side of apical plasma membrane", "External side of plasma membrane", "Extrinsic component of cytoplasmic side of plasma membrane", "Extrinsic component of endoplasmic reticulum membrane", "Extrinsic component of endosome membrane", "Extrinsic component of external side of plasma membrane", "Extrinsic component of membrane", "Extrinsic component of mitochondrial inner membrane", "Extrinsic component of organelle membrane", "Extrinsic component of plasma membrane", "Extrinsic component of postsynaptic membrane", "Extrinsic component of postsynaptic specialization membrane", "Extrinsic component of synaptic membrane", "F actin capping protein complex", "Fanconi anaemia nuclear complex", "Fascia adherens", "Female germ cell nucleus", "Female pronucleus", "Fhf complex", "Fibrillar center", "Ficolin 1 rich granule", "Ficolin 1 rich granule lumen", "Ficolin 1 rich granule membrane", "Filamentous actin", "Filopodium", "Filopodium membrane", "Filopodium tip", "Filtration diaphragm", "Flemming body", "Flotillin complex", "Gaba ergic synapse", "Gamma secretase complex", "Gamma tubulin complex", "Gamma tubulin large complex", "Gap junction", "Gator2 complex", "Gemini of coiled bodies", "Germ cell nucleus", "Gid complex", "Glial cell projection", "Glutamatergic synapse", "Glycinergic synapse", "Glycogen granule", "Glycoprotein complex", "Golgi apparatus", "Golgi apparatus subcompartment", "Golgi associated vesicle", "Golgi associated vesicle membrane", "Golgi cis cisterna", "Golgi cisterna", "Golgi cisterna membrane", "Golgi lumen", "Golgi medial cisterna", "Golgi membrane", "Golgi stack", "Golgi trans cisterna", "Golgi transport complex", "Gpi anchor transamidase complex", "Granular component", "Growth cone membrane", "Gtpase complex", "Guanyl nucleotide exchange factor complex", "H3 histone acetyltransferase complex", "H4 h2a histone acetyltransferase complex", "H4 histone acetyltransferase complex", "Haus complex", "Hemidesmosome", "Hemoglobin complex", "Heterochromatin", "Hfe transferrin receptor complex", "High density lipoprotein particle", "Hippocampal mossy fiber", "Hippocampal mossy fiber to ca3 synapse", "Histone deacetylase complex", "Histone methyltransferase complex", "Histone pre mrna 3 end processing complex", "Hops complex", "Host cellular component", "Hrd1p ubiquitin ligase erad l complex", "Hulc complex", "I band", "Ikappab kinase complex", "Immunological synapse", "Inclusion body", "Inflammasome complex", "Inhibitory synapse", "Inner mitochondrial membrane protein complex", "Ino80 complex", "Ino80 type complex", "Insulin responsive compartment", "Integral component of cytoplasmic side of endoplasmic reticulum membrane", "Integral component of lysosomal membrane", "Integral component of presynaptic active zone membrane", "Integral component of synaptic vesicle membrane", "Integrator complex", "Integrin complex", "Intercalated disc", "Intercellular bridge", "Intercellular canaliculus", "Intermediate filament", "Intermediate filament cytoskeleton", "Intracellular protein containing complex", "Intraciliary transport particle", "Intraciliary transport particle b", "Intrinsic component of endoplasmic reticulum membrane", "Intrinsic component of golgi membrane", "Intrinsic component of mitochondrial inner membrane", "Intrinsic component of mitochondrial membrane", "Intrinsic component of mitochondrial outer membrane", "Intrinsic component of nuclear inner membrane", "Intrinsic component of organelle membrane", "Intrinsic component of peroxisomal membrane", "Intrinsic component of plasma membrane", "Intrinsic component of postsynaptic density membrane", "Intrinsic component of postsynaptic membrane", "Intrinsic component of postsynaptic specialization membrane", "Intrinsic component of presynaptic active zone membrane", "Intrinsic component of presynaptic membrane", "Intrinsic component of synaptic membrane", "Intrinsic component of synaptic vesicle membrane", "Intrinsic component of vacuolar membrane", "Ion channel complex", "Iron sulfur cluster assembly complex", "Iswi type complex", "Juxtaparanode region of axon", "Keratin filament", "Kinesin complex", "Kinetochore microtubule", "Lamellar body", "Lamellipodium", "Lamellipodium membrane", "Lamin filament", "Laminin complex", "Large ribosomal subunit", "Late endosome", "Late endosome membrane", "Lateral element", "Lateral part of cell", "Lateral plasma membrane", "Leading edge membrane", "Lewy body", "Lipid droplet", "Lipopolysaccharide receptor complex", "Low density lipoprotein particle", "Lsm1 7 pat1 complex", "Lsm2 8 complex", "Lumenal side of endoplasmic reticulum membrane", "Lumenal side of membrane", "Lysosomal lumen", "M band", "Magnesium dependent protein serine threonine phosphatase complex", "Main axon", "Male germ cell nucleus", "Male pronucleus", "Manchette", "Mcm complex", "Mcrd mediated mrna stability complex", "Mediator complex", "Meiotic cohesin complex", "Meiotic spindle", "Membrane coat", "Membrane microdomain", "Membrane protein complex", "Messenger ribonucleoprotein complex", "Methylosome", "Methyltransferase complex", "Mhc class i peptide loading complex", "Mhc class i protein complex", "Mhc protein complex", "Mib complex", "Micos complex", "Microbody", "Microbody lumen", "Microbody membrane", "Microfibril", "Microtubule", "Microtubule associated complex", "Microtubule bundle", "Microtubule cytoskeleton", "Microtubule end", "Microtubule minus end", "Microtubule organizing center", "Microtubule organizing center attachment site", "Microtubule plus end", "Microvillus", "Microvillus membrane", "Midbody", "Mismatch repair complex", "Mitochondria associated endoplasmic reticulum membrane", "Mitochondrial alpha ketoglutarate dehydrogenase complex", "Mitochondrial crista", "Mitochondrial envelope", "Mitochondrial intermembrane space protein transporter complex", "Mitochondrial large ribosomal subunit", "Mitochondrial matrix", "Mitochondrial permeability transition pore complex", "Mitochondrial protein containing complex", "Mitochondrial proton transporting atp synthase complex coupling factor f o", "Mitochondrial pyruvate dehydrogenase complex", "Mitochondrial small ribosomal subunit", "Mitochondrial tricarboxylic acid cycle enzyme complex", "Mitochondrion", "Mitotic cohesin complex", "Mitotic spindle", "Mitotic spindle astral microtubule", "Mitotic spindle microtubule", "Mitotic spindle midzone", "Mitotic spindle pole", "Mks complex", "Mll1 2 complex", "Mll3 4 complex", "Mmxd complex", "Mon1 ccz1 complex", "Motile cilium", "Mpp7 dlg1 lin7 complex", "Mrna cleavage and polyadenylation specificity factor complex", "Mrna cleavage factor complex", "Mrna editing complex", "Multimeric ribonuclease p complex", "Multivesicular body", "Multivesicular body membrane", "Myelin sheath", "Myelin sheath abaxonal region", "Myelin sheath adaxonal region", "Myofilament", "Myosin complex", "Myosin filament", "Myosin ii complex", "N terminal protein acetyltransferase complex", "Nadh dehydrogenase complex", "Nascent polypeptide associated complex", "Nata complex", "Nbaf complex", "Neurofibrillary tangle", "Neurofilament", "Neuromuscular junction", "Neuron projection", "Neuron projection cytoplasm", "Neuron projection membrane", "Neuron projection terminus", "Neuron spine", "Neuron to neuron synapse", "Neuronal dense core vesicle", "Neuronal ribonucleoprotein granule", "Neurotransmitter receptor complex", "Nlrp3 inflammasome complex", "Nls dependent protein nuclear import complex", "Node of ranvier", "Non motile cilium", "Nonhomologous end joining complex", "Npbaf complex", "Nsl complex", "Nuclear body", "Nuclear chromosome", "Nuclear cyclin dependent protein kinase holoenzyme complex", "Nuclear envelope", "Nuclear envelope lumen", "Nuclear exosome rnase complex", "Nuclear inclusion body", "Nuclear inner membrane", "Nuclear lamina", "Nuclear membrane", "Nuclear outer membrane", "Nuclear outer membrane endoplasmic reticulum membrane network", "Nuclear periphery", "Nuclear pore", "Nuclear pore central transport channel", "Nuclear pore nuclear basket", "Nuclear pore outer ring", "Nuclear protein containing complex", "Nuclear replication fork", "Nuclear rna export factor complex", "Nuclear speck", "Nuclear stress granule", "Nuclear ubiquitin ligase complex", "Nucleocytoplasmic transport complex", "Nucleoid", "Nucleolar ribonuclease p complex", "Nucleolus", "Nucleotide activated protein kinase complex", "Nucleotide excision repair complex", "Nurd complex", "Nurf complex", "Oligosaccharyltransferase complex", "Organellar ribosome", "Organelle envelope lumen", "Organelle inner membrane", "Organelle membrane contact site", "Organelle subcompartment", "Origin recognition complex", "Outer dense fiber", "Outer kinetochore", "Outer membrane", "Outer mitochondrial membrane protein complex", "Oxidoreductase complex", "Oxoglutarate dehydrogenase complex", "P body", "Palmitoyltransferase complex", "Pam complex tim23 associated import motor", "Parallel fiber to purkinje cell synapse", "Paranodal junction", "Paranode region of axon", "Paraspeckles", "Pcg protein complex", "Peptidase complex", "Peptidase inhibitor complex", "Pericentric heterochromatin", "Pericentriolar material", "Perikaryon", "Perinuclear endoplasmic reticulum", "Perinuclear region of cytoplasm", "Perinucleolar compartment", "Phagocytic cup", "Phagocytic vesicle", "Phagocytic vesicle lumen", "Phagocytic vesicle membrane", "Phagolysosome", "Phagophore assembly site", "Phagophore assembly site membrane", "Phosphatase complex", "Phosphatidylinositol 3 kinase complex", "Phosphatidylinositol 3 kinase complex class iii", "Phospholipid translocating atpase complex", "Phosphorylase kinase complex", "Photoreceptor connecting cilium", "Photoreceptor inner segment", "Photoreceptor outer segment", "Photoreceptor ribbon synapse", "Pi body", "Picln sm protein complex", "Pigment granule", "Pinosome", "Pip body", "Plasma membrane protein complex", "Plasma membrane raft", "Plasma membrane region", "Plasma membrane signaling receptor complex", "Platelet alpha granule", "Platelet alpha granule lumen", "Platelet alpha granule membrane", "Platelet dense granule", "Platelet dense granule lumen", "Platelet dense granule membrane", "Platelet dense tubular network", "Platelet dense tubular network membrane", "Pml body", "Podosome", "Polar microtubule", "Pole plasm", "Polymeric cytoskeletal fiber", "Polysomal ribosome", "Polysome", "Pore complex", "Post mrna release spliceosomal complex", "Postsynapse", "Postsynaptic cytoskeleton", "Postsynaptic cytosol", "Postsynaptic density intracellular component", "Postsynaptic density membrane", "Postsynaptic endocytic zone", "Postsynaptic endosome", "Postsynaptic membrane", "Postsynaptic recycling endosome", "Postsynaptic specialization intracellular component", "Postsynaptic specialization membrane", "Potassium channel complex", "Prc1 complex", "Pre snornp complex", "Precatalytic spliceosome", "Prefoldin complex", "Preribosome", "Preribosome large subunit precursor", "Preribosome small subunit precursor", "Prespliceosome", "Presynapse", "Presynaptic active zone", "Presynaptic active zone cytoplasmic component", "Presynaptic active zone membrane", "Presynaptic cytoskeleton", "Presynaptic cytosol", "Presynaptic endocytic zone", "Presynaptic membrane", "Pronucleus", "Protease inhibitor complex", "Proteasome accessory complex", "Proteasome complex", "Proteasome core complex", "Proteasome core complex alpha subunit complex", "Proteasome core complex beta subunit complex", "Proteasome regulatory particle", "Proteasome regulatory particle base subcomplex", "Proteasome regulatory particle lid subcomplex", "Protein acetyltransferase complex", "Protein complex involved in cell adhesion", "Protein dna complex", "Protein kinase complex", "Protein lipid complex", "Protein phosphatase 4 complex", "Protein phosphatase type 1 complex", "Protein phosphatase type 2a complex", "Proton transporting atp synthase complex", "Proton transporting atp synthase complex catalytic core f 1", "Proton transporting atp synthase complex coupling factor f o", "Proton transporting two sector atpase complex", "Proton transporting two sector atpase complex catalytic domain", "Proton transporting two sector atpase complex proton transporting domain", "Proton transporting v type atpase complex", "Proton transporting v type atpase v0 domain", "Proton transporting v type atpase v1 domain", "Proximal dendrite", "Prp19 complex", "Pseudopodium", "Ptw pp1 phosphatase complex", "Pwp2p containing subcomplex of 90s preribosome", "R2tp complex", "Ragulator complex", "Rdna heterochromatin", "Receptor complex", "Recycling endosome", "Recycling endosome membrane", "Replication fork", "Replisome", "Respirasome", "Respiratory chain complex iii", "Respiratory chain complex iv", "Retromer complex", "Ribbon synapse", "Ribonuclease mrp complex", "Ribonuclease p complex", "Ribonucleoprotein complex", "Ribonucleoprotein granule", "Ribose phosphate diphosphokinase complex", "Ribosomal subunit", "Ribosome", "Ripoptosome", "Risc loading complex", "Rna cap binding complex", "Rna polymerase complex", "Rna polymerase i complex", "Rna polymerase ii core complex", "Rna polymerase ii holoenzyme", "Rna polymerase ii transcription regulator complex", "Rna polymerase ii transcription repressor complex", "Rna polymerase iii complex", "Rna polymerase iii transcription regulator complex", "Rnai effector complex", "Rough endoplasmic reticulum", "Rough endoplasmic reticulum membrane", "Rpap3 r2tp prefoldin like complex", "Ruffle", "Ruffle membrane", "Saga complex", "Saga type complex", "Sarcolemma", "Sarcoplasm", "Sarcoplasmic reticulum lumen", "Sarcoplasmic reticulum membrane", "Scar complex", "Scf ubiquitin ligase complex", "Schaffer collateral ca1 synapse", "Schmidt lanterman incisure", "Sec61 translocon complex", "Secondary lysosome", "Secretory granule", "Secretory granule membrane", "Secretory vesicle", "Seh1 associated complex", "Semaphorin receptor complex", "Septin cytoskeleton", "Serine protease inhibitor complex", "Set1c compass complex", "Sex chromatin", "Sex chromosome", "Shelterin complex", "Side of membrane", "Signal peptidase complex", "Signal recognition particle", "Sin3 complex", "Sin3 type complex", "Site of dna damage", "Site of double strand break", "Site of polarized growth", "Sm like protein family complex", "Small ribosomal subunit", "Small subunit processome", "Smc5 smc6 complex", "Smn complex", "Smn sm protein complex", "Smooth endoplasmic reticulum", "Smooth endoplasmic reticulum membrane", "Snare complex", "Sno s rna containing ribonucleoprotein complex", "Sodium potassium exchanging atpase complex", "Somatodendritic compartment", "Sorting endosome", "Spanning component of membrane", "Specific granule", "Specific granule lumen", "Specific granule membrane", "Spectrin", "Spectrin associated cytoskeleton", "Sperm annulus", "Sperm connecting piece", "Sperm fibrous sheath", "Sperm head", "Sperm head plasma membrane", "Sperm midpiece", "Sperm plasma membrane", "Sperm principal piece", "Spermatoproteasome complex", "Spherical high density lipoprotein particle", "Spindle", "Spindle microtubule", "Spindle midzone", "Spindle pole", "Spindle pole centrosome", "Spliceosomal complex", "Spliceosomal snrnp complex", "Spliceosomal tri snrnp complex", "Stereocilia coupling link", "Stereocilium bundle", "Stereocilium membrane", "Stereocilium tip", "Striated muscle thin filament", "Sumo ligase complex", "Supramolecular complex", "Supramolecular polymer", "Swi snf complex", "Swr1 complex", "Synapse", "Synaptic cleft", "Synaptic membrane", "Synaptic vesicle membrane", "Synaptonemal structure", "T tubule", "Telomerase holoenzyme complex", "Terminal bouton", "Tertiary granule", "Tertiary granule lumen", "Tertiary granule membrane", "Tetraspanin enriched microdomain", "Tho complex", "Tight junction", "Tim22 mitochondrial import inner membrane insertion complex", "Tim23 mitochondrial import inner membrane translocase complex", "Tor complex", "Torc1 complex", "Trans golgi network", "Trans golgi network membrane", "Trans golgi network transport vesicle", "Trans golgi network transport vesicle membrane", "Transcription elongation factor complex", "Transcription export complex", "Transcription export complex 2", "Transcription factor tfiia complex", "Transcription factor tfiid complex", "Transcription factor tfiih holo complex", "Transcription factor tfiiic complex", "Transcription factor tftc complex", "Transcription preinitiation complex", "Transcription regulator complex", "Transcription repressor complex", "Transferase complex", "Transferase complex transferring phosphorus containing groups", "Translation preinitiation complex", "Translocon complex", "Transport vesicle", "Transport vesicle membrane", "Transporter complex", "Trapp complex", "Tricarboxylic acid cycle enzyme complex", "Triglyceride rich plasma lipoprotein particle", "Trna methyltransferase complex", "Trna splicing ligase complex", "Tubular endosome", "U1 snrnp", "U12 type spliceosomal complex", "U2 snrnp", "U2 type catalytic step 2 spliceosome", "U2 type spliceosomal complex", "U2af complex", "U4 snrnp", "U5 snrnp", "U6 snrnp", "U7 snrnp", "Ubiquinone biosynthesis complex", "Ubiquitin conjugating enzyme complex", "Ubiquitin ligase complex", "Unconventional myosin complex", "Uniplex complex", "Vacuolar lumen", "Vacuolar membrane", "Vacuolar proton transporting v type atpase v0 domain", "Vacuole", "Varicosity", "Vcp npl4 ufd1 aaa atpase complex", "Vesicle coat", "Vesicle lumen", "Vesicle membrane", "Vesicle tethering complex", "Voltage gated calcium channel complex", "Wash complex", "Weibel palade body", "Wnt signalosome", "X chromosome", "Xy body", "Zona pellucida receptor complex", "Zonula adherens", "Zymogen granule", "Zymogen granule membrane"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AARS", "AARS2", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADNP", "ADPGK", "ADRM1", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "ALYREF", "AMFR", "AMOT", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOC1", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC10", "ARMCX3", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG3", "ATG5", "ATG7", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C10orf76", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C17orf75", "C19orf70", "C1QBP", "C1orf35", "C2CD2L", "C2CD5", "C2orf49", "C3orf58", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CAST", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC134", "CCDC137", "CCDC22", "CCDC47", "CCDC51", "CCDC58", "CCDC86", "CCDC93", "CCDC94", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPH", "CENPK", "CENPP", "CENPU", "CENPV", "CEP131", "CEP170", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIRBP", "CISD1", "CISD2", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLU", "CMPK1", "CNN3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CTBP1", "CTBP2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTR9", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNTTIP2", "DOCK1", "DOCK7", "DOLPP1", "DPF2", "DPM1", "DPP9", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP3", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5A", "EIF6", "ELAC2", "ELAVL1", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM129B", "FAM162A", "FAM173A", "FAM207A", "FAM208A", "FAM3C", "FAM49B", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FNBP1", "FNBP4", "FNDC3A", "FNTA", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC1", "FUNDC2", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GGA1", "GGCX", "GGH", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLOD4", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLYR1", "GM2A", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH11", "GPATCH4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSR", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEBP2", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMCES", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "ISOC1", "IST1", "ISY1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPK1", "ITPRIP", "ITSN2", "IVD", "JAGN1", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KNOP1", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC45", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYSMD3", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METTL1", "METTL13", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD8", "MGAT1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRFAP1", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS6", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTF2", "MTFP1", "MTFR1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTX1", "MTX2", "MUT", "MVD", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NAF1", "NAGLU", "NAMPT", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NENF", "NES", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C3A", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANX1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAWR", "PAX6", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD11", "PDZD8", "PECR", "PEF1", "PELP1", "PES1", "PET100", "PEX14", "PEX19", "PEX5", "PEX6", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGK1", "PGM1", "PGM2", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF5A", "PHF6", "PHF8", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PISD", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA2", "PPAN", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2C", "PSAP", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN23", "PTPRF", "PTRH2", "PUM3", "PURA", "PUS1", "PWP1", "PWP2", "PXMP2", "PXMP4", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN2", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCB", "RTF1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCOC", "SCP2", "SCRIB", "SCRN1", "SCYL1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHCBP1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L2", "SKP1", "SKP2", "SLAIN2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMU1", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAMM41", "TAP1", "TAPBP", "TARDBP", "TARS2", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TCTN3", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THADA", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF2", "TM9SF4", "TMA16", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM14C", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM206", "TMEM214", "TMEM230", "TMEM259", "TMEM30A", "TMEM33", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNKS1BP1", "TNPO1", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM27", "TRIM28", "TRIM32", "TRIP12", "TRIP13", "TRIP4", "TRIT1", "TRMT10C", "TRMT112", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TTC1", "TTC19", "TTC26", "TTC37", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "UBA1", "UBA2", "UBA5", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UFD1", "UFL1", "UFSP2", "UGCG", "UGGT1", "UGT8", "UHRF1", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "USMG5", "USO1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMA21", "VMP1", "VPS13A", "VPS13D", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "VWA8", "WAPL", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR61", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WRAP73", "WRN", "WTAP", "XAB2", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H14", "ZC3H18", "ZC3HC1", "ZCCHC11", "ZCCHC8", "ZCRB1", "ZDHHC13", "ZFPL1", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM2", "ZMYND8", "ZNF326", "ZNF622", "ZNF638", "ZPR1", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABAT", "ABCB6", "ABCB7", "ABCC4", "ABCD4", "ACADVL", "ACBD3", "ACOX3", "ACP2", "ACSL6", "ACTN1", "ACTN4", "ACTR8", "ADA", "ADAM17", "ADD3", "AFG3L2", "AGPS", "AHCYL1", "AIFM1", "AIP", "AKT1", "AKT2", "ALCAM", "ALDH1A2", "AMOT", "ANAPC7", "ANGEL1", "ANK3", "ANKLE2", "ANXA7", "APBB1", "APLP2", "APP", "ARHGAP1", "ARID1A", "ARMC10", "ARVCF", "ASNA1", "ASPH", "ATAD3B", "ATL2", "ATL3", "ATP13A1", "ATP2A2", "ATP2B1", "ATP5A1", "ATP5L", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "AURKA", "B3GALT6", "B4GALT1", "B4GALT3", "B4GAT1", "BAIAP2", "BAZ1B", "BAZ2A", "BBS4", "BCAS2", "BCLAF1", "BCR", "BECN1", "BICD2", "BSG", "BUB1B", "BYSL", "C12orf73", "C2CD2L", "C3orf58", "CADM1", "CAMK1", "CAMK2G", "CAMSAP3", "CANT1", "CANX", "CAPN2", "CAPN5", "CAPZB", "CASK", "CBX5", "CCDC22", "CCDC93", "CCT2", "CD320", "CDC20", "CDC42BPB", "CDC45", "CDC5L", "CDCA8", "CDH2", "CDK1", "CDK16", "CENPH", "CENPK", "CEP131", "CEP250", "CEP290", "CEPT1", "CERS1", "CERS2", "CFDP1", "CHAF1B", "CHAMP1", "CHCHD3", "CHMP1A", "CHMP5", "CHST14", "CKAP4", "CLCN3", "CLCN7", "CLN5", "CLN6", "CLSTN3", "CNNM4", "COA3", "COG3", "COLEC12", "COPB2", "COPG1", "COPS2", "COPS3", "COPS4", "COPS7B", "COX15", "COX2", "COX5A", "CPT2", "CRNKL1", "CRTAP", "CSNK1A1", "CTNNA1", "CTNNB1", "CTNNBL1", "CTSA", "CWC15", "CYB5B", "CYFIP1", "CYFIP2", "CYP51A1", "DCTN1", "DCTN3", "DDRGK1", "DDX20", "DDX56", "DHCR24", "DHCR7", "DHX36", "DIABLO", "DNAJB12", "DNAJC1", "DNAJC10", "DOCK7", "DYM", "ECE1", "EEA1", "EHD4", "EIF2A", "EIF2S1", "EIF2S3", "EIF4H", "EMD", "EML4", "ENY2", "EPDR1", "EPHA7", "EPHX1", "ERAP1", "ERBIN", "ERC1", "ERCC3", "ERCC6L", "ERGIC3", "EXOC7", "EZH2", "EZR", "FAM129B", "FAM207A", "FAM3C", "FAM49B", "FBL", "FECH", "FERMT2", "FGFR1OP", "FKBP7", "FKRP", "FLII", "FLNC", "FLOT1", "FMR1", "FNBP1", "FNTA", "FOXRED1", "FRG1", "FTSJ3", "FUCA1", "FUCA2", "FXR1", "GAA", "GAK", "GAL", "GALNT1", "GBA", "GBF1", "GCC1", "GCC2", "GEMIN5", "GEMIN8", "GGCX", "GHDC", "GHITM", "GINS4", "GLA", "GLB1", "GLG1", "GLMN", "GLT8D1", "GNA13", "GNG12", "GNS", "GOLGA2", "GOLGA5", "GOLIM4", "GOLM1", "GPAM", "GPR107", "GPR108", "GSR", "GTF2B", "GTF2F2", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP4", "GUSB", "HAUS1", "HAUS4", "HAUS5", "HELLS", "HIP1", "HLA-A", "HLA-C", "HLA-F", "HMGB2", "HMMR", "HMOX2", "HNRNPA3", "HNRNPH2", "HOOK1", "HOOK2", "HOOK3", "HPS6", "HS1BP3", "HSPA8", "IDH2", "IFT52", "IGF2R", "IK", "IKBIP", "IMMT", "IMPAD1", "INA", "INCENP", "INPP4A", "INTS11", "IQCB1", "IQGAP1", "IQGAP3", "ISOC1", "ISY1", "ITGA2", "ITM2C", "ITSN2", "JAM3", "KDELR1", "KIAA0319L", "KIF11", "KIF22", "KIF23", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KNSTRN", "KNTC1", "KPNA2", "KPNB1", "KTN1", "LAMB1", "LAMP1", "LAMTOR2", "LANCL2", "LAPTM4A", "LBR", "LEMD3", "LGALS3BP", "LGMN", "LIMA1", "LLGL1", "LMAN1", "LMBRD1", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LPGAT1", "LRPAP1", "LRWD1", "LTV1", "M6PR", "MAD1L1", "MAN1A2", "MAN2B1", "MANEA", "MAPRE1", "MAPRE2", "MBOAT7", "MCM6", "MCUB", "MED17", "MED25", "MED4", "MFAP1", "MFF", "MFSD10", "MFSD8", "MICU1", "MICU2", "MID1", "MIF", "MMGT1", "MPC2", "MPG", "MPP2", "MPP5", "MPRIP", "MPV17", "MPV17L2", "MRE11", "MRPL4", "MRPL40", "MRPL45", "MRPS11", "MRPS16", "MSH3", "MSN", "MTA1", "MTBP", "MTCH2", "MTG1", "MTX1", "MTX2", "MXRA7", "MYCBP2", "MYH10", "MYH14", "MYH9", "NAGLU", "NBAS", "NBN", "NCAPD2", "NCAPH", "NCEH1", "NCSTN", "ND1", "NDC1", "NDE1", "NDUFB3", "NDUFB4", "NDUFS2", "NDUFS6", "NDUFS7", "NEFL", "NEFM", "NENF", "NIFK", "NNT", "NOB1", "NOC4L", "NONO", "NOP14", "NOP58", "NOP9", "NPC1", "NPC2", "NPTN", "NSL1", "NSUN2", "NUBP2", "NUCB1", "NUCB2", "NUMA1", "NUP107", "NUP37", "NUP93", "OCLN", "OPA1", "OSBPL2", "OSBPL3", "OXA1L", "PAF1", "PARL", "PCID2", "PCYOX1", "PDCL3", "PDE4DIP", "PDS5A", "PDS5B", "PGRMC2", "PHF10", "PHF6", "PIBF1", "PIGG", "PIGT", "PLA2G15", "PLBD2", "PLD3", "PLD6", "PLEC", "PMF1", "PMPCA", "POLRMT", "POMGNT2", "PON2", "PPFIA1", "PPIG", "PPOX", "PPP2R5C", "PPP4R1", "PPP4R3A", "PPT1", "PPT2", "PRC1", "PRCP", "PREB", "PREPL", "PRKAG1", "PRKRA", "PRPF19", "PSAP", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMD11", "PSMG1", "PTPMT1", "PTPRF", "PXMP2", "RAB10", "RAB18", "RAB24", "RAB34", "RAB3GAP1", "RAB4A", "RAB5B", "RAC1", "RAD50", "RAI14", "RAPGEF2", "RBM22", "RCN2", "REEP2", "REEP3", "REEP4", "REEP5", "RHOG", "RIF1", "RIOK2", "RNASET2", "ROCK1", "ROCK2", "RPLP1", "RPN1", "RPS3", "RRBP1", "RRP1", "RRP1B", "RTF1", "RTN2", "RTN4", "SACM1L", "SAR1B", "SCAMP2", "SCARB1", "SCARB2", "SCCPDH", "SDCCAG3", "SDF4", "SEC13", "SEC23B", "SEC62", "SEH1L", "SET", "SFPQ", "SFXN4", "SGPL1", "SIGMAR1", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A10", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A42", "SLC2A1", "SLC35B2", "SLC4A7", "SLC7A1", "SLC7A5", "SLTM", "SMARCA4", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMDT1", "SNU13", "SNW1", "SNX2", "SNX27", "SNX4", "SNX8", "SNX9", "SORD", "SORT1", "SPART", "SPC24", "SPDL1", "SPECC1", "SPHK2", "SPPL2A", "SPTAN1", "SPTBN1", "SQOR", "SSNA1", "STAG1", "STAG2", "STK4", "STOM", "STX10", "STX12", "STX4", "STX6", "STX7", "SUN2", "SURF4", "SURF6", "SV2A", "SYMPK", "SYNCRIP", "SYNE2", "SYNJ2BP", "SYS1", "TACC3", "TDRKH", "TEDC1", "TFG", "TFRC", "TGFBRAP1", "TGOLN2", "THOC1", "THOP1", "THRAP3", "TIMM17A", "TM9SF2", "TMEM126A", "TMEM165", "TMEM192", "TMEM201", "TMEM206", "TMEM59", "TMEM70", "TMEM87A", "TMTC3", "TOM1L2", "TOMM40", "TPBG", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TRAM1", "TRIM13", "TRIM21", "TRIM27", "TRIM32", "TSPAN3", "TSR1", "TTC19", "TTC26", "TUBGCP2", "TUBGCP3", "TWNK", "UBE2G2", "UBE2S", "UBIAD1", "UFL1", "UFSP2", "UGCG", "UNC119", "UNC119B", "UQCC1", "UQCC2", "UQCRC2", "USP22", "USP8", "UTRN", "VAMP7", "VCL", "VDAC1", "VDAC2", "VEZT", "VIM", "VKORC1L1", "VMP1", "VWA8", "WASF2", "WASHC3", "WASHC5", "WDR45B", 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0.0050858864192633 6.934466019417476 18.83009708737864 1.2767207242593377 0.1489147276149277 2.386872767465543 1.965791668457755 1.709796217367629 0.2208345231085202 0.0506073598520428 0.0213334360876883 0.0105950719619242 0.0009743779436676 8.337420261083056e-05 +Anion transmembrane transporter activity 25 57 2.6323732433504663 0.0084790656030746 18.594660194174757 45.61893203883495 1.6222323024349488 0.2373683627198559 9.346785472607134 6.017202751823004 1.8117646078257517 0.3183345645365742 1.0 0.1184945425124205 0.0069373308663509 0.0033982880419941 0.0003885024837068 +Lipid binding 30 157 2.608249537907955 0.0091006584248858 30.883495145631063 138.65533980582524 0.9844637598707308 0.4289871747751645 8.92748670410201 14.760635317682617 1.446857667744565 0.4068298387995807 0.0818216007315708 0.0047170389987107 0.001091221732986 0.0060508412169139 0.0190882347712494 +Signaling receptor regulator activity 8 23 2.574594925710308 0.0100357543748448 4.072815533980583 17.339805825242717 0.7311308082630681 0.4520633016494398 2.421493327854957 2.496807274147909 0.9157780911218903 0.317372323464707 1.0 0.0003708570183047 0.0006329783107867 0.0082077294132096 0.008617935758856 +Exopeptidase activity 11 34 2.572909071734808 0.0100847699036699 9.74514563106796 31.84223300970874 1.193034763402526 0.2308543476384821 3.0338864063053523 1.9513159274241312 1.6646797512653713 0.2911825093455628 0.0639068253026823 0.000185314654978 0.000274261654928 0.0006279861154086 3.0236033691112305e-05 +Threonine type endopeptidase activity 5 8 2.5035869349846447 0.0122941472916477 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 0.0461123069087121 0.0038356556834428 3.59582749836129e-08 2.285385949037992e-06 +Threonine type peptidase activity 5 8 2.5035869349846447 0.0122941472916477 3.8106796116504857 8.762135922330097 1.392634148189787 0.2146040118876429 1.6274593113109357 0.6695334565847216 1.0340073360925757 0.2572219198248905 1.0 0.0639684350193291 0.0075668597133861 4.739959742822594e-07 2.763867591720716e-05 +Ceramide binding 3 6 2.4815891606573257 0.0130797983298076 2.8228155339805827 5.048543689320389 1.42330045764979 0.1242195400491618 1.17628831869178 0.9309003969609838 1.481980135982154 0.2133994029014766 1.0 0.0016377422378922 5.153776434246189e-06 0.0001991597833083 0.0027834726260547 +Sphingolipid binding 3 7 2.456421118203053 0.0140328606163895 3.2305825242718447 6.810679611650485 1.3881601090528384 0.1287371848492678 1.3662849673921555 1.293404675510669 1.5116584105270494 0.2146285912590262 1.0 0.0031646532309382 2.1265295896701374e-05 0.0007750266814789 0.0098193480789534 +Phospholipid binding 29 106 2.45365604367249 0.0141412170279222 18.890776699029125 88.4635922330097 0.777309720287493 0.452120200534915 6.970479526806733 10.51702894240924 1.1988133109990275 0.3785217149858343 0.2817240684487549 0.0133340434123436 0.0022687260933392 0.0620780551805057 0.0380413132251025 +Organic anion transmembrane transporter activity 17 37 2.4223871418848657 0.0154189142963765 12.951456310679612 30.182038834951456 1.56101282472555 0.2452312368187786 6.880574373146614 3.5222410835885483 1.575669523214114 0.314839840161206 1.0 0.3315322885250054 0.0471171920041226 0.0543296939149059 0.0219681008445407 +Tetrapyrrole binding 6 23 2.408937900920556 0.0159990199979553 7.402912621359223 16.83252427184466 2.0044897428967667 0.1259264696495541 2.9589081005845346 2.0417036568087963 1.3464702305086589 0.2177422235164347 1.0 0.225458320485449 0.0145863017156454 0.0094868932073139 0.0042820394936164 +Pdz domain binding 6 17 2.342349186339842 0.019162776886481 3.9271844660194177 14.419902912621358 0.5491111169746481 0.4670646684125319 2.189901543859342 2.754676868666853 0.9064591556484958 0.2972085908111159 1.0 0.2106238865638343 0.0817843887075946 0.1193188519501932 0.0333354886378474 +Serine type exopeptidase activity 5 7 2.3280951554281746 0.0199070514991175 3.783980582524272 6.997572815533981 1.020609253431403 0.1137432544246352 1.3363606860118669 0.0492066381861973 1.87035730934538 0.1990592265121372 0.0096716725706127 0.0007650215967213 6.726920677389607e-05 3.788095303003865e-05 9.533521740063692e-07 +Protease binding 7 33 2.3041592990294024 0.0212137030089223 6.186893203883495 26.72087378640777 0.4143971461280679 0.5282949986204084 3.052378200340675 3.815814208193157 0.8315156489156551 0.2995827216567743 0.082041919335586 0.0531691841805127 0.0067100569695188 0.0418340682466743 0.0376283333624949 +Hydrolase activity acting on glycosyl bonds 13 31 2.3040710729852028 0.0212186542459933 10.133495145631068 28.40776699029126 0.6089784953463463 0.2409908190925149 3.36301188653944 3.2424277527979313 1.935823411407979 0.3010513017078077 1.0 0.2922756805728106 0.1529837701743424 0.0018365459096632 9.056333742184927e-06 +Abc type transporter activity 2 12 2.294754892215212 0.0217471750422855 3.0194174757281553 7.652912621359223 0.9831250219385844 0.2361571806590424 1.9482657586917436 2.350049836723345 1.2743804993059251 0.258194993176919 1.0 0.1114021565620111 0.2127898194125335 0.0215683584236732 0.1194171261960574 +Scaffold protein binding 3 22 2.199380916705465 0.0278508484049013 4.453883495145631 19.78640776699029 0.4014949507499379 0.5241128000695782 2.407574912084857 2.8237910393168404 0.8563473729948742 0.2942678929205971 1.0 0.1916891885455893 0.0088720794008613 0.0227330174276438 0.1740747384317906 +Carboxypeptidase activity 4 11 2.176050895900084 0.0295514550572459 3.941747572815534 11.944174757281552 0.6619369631013473 0.2217581052142344 1.5253536449314826 0.7722681563953175 1.6063564059694095 0.2594343390807456 0.0256023215689562 0.0056070915236824 0.0014613866465803 0.0024022577840735 0.0052582215982291 +Antigen binding 4 9 2.1752794622987097 0.0296091806057916 2.504854368932039 6.936893203883495 1.1926555941065955 0.2669458193807861 1.6287691845260013 1.3674077446215156 0.9067202373946956 0.2605304200525402 1.0 0.1029565435856987 0.1975594178204269 0.0172025832638257 0.0986013223955862 +Glycolipid binding 4 11 2.1540915379672865 0.0312329940243829 3.95873786407767 9.17233009708738 1.1300394975336625 0.1723818604496332 1.779261971800237 1.789101691327159 1.517965150696512 0.2390589148665743 1.0 0.0771453392642774 0.0005152543640852 0.0073447144383531 0.0010145405611514 +Ion transmembrane transporter activity 45 124 2.14424936784769 0.0320129113664922 37.34466019417476 101.497572815534 2.0154097423383375 0.2561362875319209 17.172953606300336 11.579295798802024 2.277787478419462 0.3756175790939143 1.0 0.057339521218393 0.0027058535880624 0.0005101889066339 0.0001066217297601 +Retromer complex binding 2 5 2.138571274848515 0.0324704059739788 1.7864077669902914 4.62378640776699 0.1266826261911074 0.4322045282144987 1.2199831722291083 0.628387698804986 1.1917576639553151 0.3183570223820515 1.0 0.0370595951599339 0.073646168181401 0.0007102815399137 0.0053334351931861 +Serine type carboxypeptidase activity 4 5 2.13260828473694 0.0329568731354554 3.0558252427184467 4.997572815533981 1.0019911760482532 0.1105835516254352 1.1231414198895626 0.0492066381861973 1.8086551291944464 0.1930654928989846 0.0053836994107949 0.0002150789234385 8.233368934226172e-06 1.6228361660218084e-06 2.672407740619558e-07 +Monooxygenase activity 2 9 2.132341204929814 0.0329788070030121 4.043689320388349 8.322815533980583 1.6049222537693364 0.1501440468766332 1.612461779657682 1.2307404965531048 1.237349324058907 0.2369071661653372 1.0 0.1197698958477507 0.0269433955752302 0.0264830942684438 0.14168603717257 +Galactosyltransferase activity 3 7 2.1282704890081643 0.0333146634254855 1.4004854368932038 4.014563106796117 0.4835514024572315 0.4297894898723106 1.1026445515529784 1.0725079733100582 1.0886375545888918 0.3129067636178667 1.0 1.0 0.1419203898220533 0.0061570039439817 0.00630824692371 +Peptide antigen binding 4 8 2.1158587414057632 0.0343568233698532 2.25 5.218446601941747 1.3488418251083294 0.2076946662826 1.4985834735457568 1.269832767279765 0.9581301458127084 0.2397273125927817 1.0 0.0683810764565047 0.1336663515258769 0.0050923434600555 0.0336357980244025 +Hydrolase activity hydrolyzing o glycosyl compounds 10 22 2.0806993698532428 0.0374614318016131 8.830097087378642 20.84223300970874 0.5983257656540719 0.2104301479001341 3.2223833352824554 2.4557961681485057 1.9540573665272416 0.2728112677124137 1.0 1.0 0.3686542667111886 0.0009743779436676 1.4177363886845684e-05 +Fad binding 5 11 2.079089388740889 0.0376091352325709 3.78883495145631 9.932038834951456 1.575439945642976 0.1698004033102896 1.8828741719818296 1.250336932628077 0.9196006746446306 0.2289411404885479 1.0 0.0065631621549981 0.0018516158363228 0.0032545859437725 0.0012863968531589 +Growth factor receptor binding 7 20 2.07343321634614 0.0381319803353636 5.233009708737864 16.303398058252426 0.6012049824390195 0.4932334837741021 2.455245557470486 2.477606131434232 0.8745174126419827 0.327387299755004 1.0 0.2291240669446297 0.4097170027262437 0.0432632841258681 0.0048031771903066 +Microtubule minus end binding 2 7 2.0568973939082222 0.0396960967283792 1.779126213592233 5.58252427184466 0.2577668152609851 0.5679927735482322 1.300579114323238 1.0406707307305358 0.8184057837553801 0.2943540019303944 1.0 0.0639684350193291 0.1253337423142017 0.0041470760753771 0.0278921605814954 +Amide binding 12 118 2.046000945893535 0.0407562776110037 22.521844660194176 102.53398058252426 0.8716704131409604 0.4134472412494542 7.596116055031058 7.786365397071367 1.2519470693533183 0.3815633057547212 0.2011891884908752 0.0003824952698453 2.4817748736818388e-05 0.0004621265146736 0.0055011245186282 +Cytokine activity 1 6 2.0439325797013965 0.0409602080559432 1.4368932038834952 5.75 0.9689346120623524 0.3423153019744804 1.105326054892273 0.6058973927039436 0.8855586242183912 0.2854448354224685 1.0 0.1071891284628969 0.0215793786244467 0.1131762501747812 0.3271248077551284 +Glycosaminoglycan binding 5 18 2.0433190618069768 0.0410208638328664 4.978155339805825 17.45631067961165 0.1337124269810174 0.5629551361084434 2.38360266105164 2.069316753377374 0.9690169198659552 0.3148101721496325 1.0 0.037406554204333 0.1269571915493486 0.2067196289529824 0.2083780450206639 +Heparin binding 2 13 2.038786273254343 0.0414713628815917 3.4344660194174756 11.91504854368932 0.417671776261347 0.5410412518682232 1.977562601051691 1.5719219414069263 0.9122022863658426 0.3149614964035694 1.0 0.0181053013145446 0.0654836355539999 0.0893115916137597 0.1644709145443467 +Organic acid transmembrane transporter activity 11 24 2.024448188601016 0.0429240578196581 8.592233009708737 21.276699029126213 1.5973629153049684 0.1905568538747131 4.4420473133518055 2.549726956007885 1.3213968531498468 0.2647933566957936 1.0 0.2752604452820565 0.0268041613697724 0.0238750792658836 0.0464752879206614 +Zinc ion binding 21 155 2.023695831028095 0.0430014578116229 28.59223300970874 139.68203883495147 -0.0405402661254739 0.6975438866599186 14.186474409757915 17.65179293730256 0.7773657878061386 0.3244829078143309 1.0 0.0885789062522531 0.1091474729658877 0.1060774371545096 0.418847891861584 +Metallopeptidase activity 11 44 2.008683154248805 0.0445707463520064 11.548543689320388 40.60436893203884 1.2053444242445344 0.3510417366391842 4.586289489033314 2.1135899474190585 1.0988837346562612 0.3462572593421246 1.0 0.0543724481878489 0.0405305960068218 0.0031061282245647 0.000451259348622 +Ionotropic glutamate receptor binding 1 5 1.9842380950813368 0.0472293036065136 1.5072815533980584 5.189320388349515 0.4352952890916908 0.5486234361141443 1.2157723137108922 0.7294648419243608 0.7662696198250318 0.294972539733417 1.0 1.0 0.1084298440104649 0.2541534411772372 0.1129571724371578 +Phosphatidylcholine binding 2 10 1.97237567650121 0.048566736417654 2.2524271844660193 7.929611650485437 1.2697801287388335 0.1567893034984199 1.081337239384838 1.04388968498945 1.4953842980517238 0.2256102823610289 1.0 0.0727733471903131 0.0098557770733155 0.0557098434243155 0.039942155971048 +Phosphatidylserine binding 2 10 1.9689311521423043 0.0489609976595155 2.029126213592233 10.060679611650484 0.6615116985008255 0.3340719518205703 1.5854698894895154 0.9597266622759548 1.1646704221215245 0.2873190862432436 0.0298109635380268 0.0075879492488378 0.0288389511657702 0.1457934990596532 0.1533018949933901 diff --git a/msigdb_gomf/metrics.json b/msigdb_gomf/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..bf6497ad2f6affde7c888a6cd8447b7a8e37bad1 --- /dev/null +++ b/msigdb_gomf/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 1427, + "title": "Average number of proteins per term", + "value": 17.852137351086196 +} \ No newline at end of file diff --git a/msigdb_gomf/paths.json b/msigdb_gomf/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..6f054f91b88c1dd048527ea06f9ff0eea18afaa3 --- /dev/null +++ b/msigdb_gomf/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_gomf/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/msigdb_gomf/result.tsv b/msigdb_gomf/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..24b122439a302541074073294f024a3f48664cd2 --- /dev/null +++ b/msigdb_gomf/result.tsv @@ -0,0 +1,434 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Peptidase activity 0.5039332790864073 3.3706012196274537 0.0007500434599805 0.657236169051229 0.0105971486870516 124 P42785,Q4J6C6,Q9HD42,P20618,O14773,P28072,Q8TCT8,P60900,P55786,Q9HB40,Q9UIQ6,P28070,P28074,P02786,Q9BXS4,P42892,Q92542,P10619,P49721,P22695,O75976,O15484,P78536,Q9H300,Q9H3G5,Q96K76,P52888,Q9NQH7,P17655,Q9NZ08,Q93009,Q16740,Q9BT78,Q99538,Q99436,O75844,Q9UPT9 37 +Molecular transducer activity 0.6412296318976615 3.1844491617612665 0.0014502978310062 0.8739500733826617 0.0180875982614903 41 P11717,Q99720,Q14108,Q4VCS5,P20645,O15118,Q9P2E9,Q8WTV0,P22466,O15173,Q15629,O75787,Q9NWH9,Q5KU26,Q15375,Q99523,P10586,Q9NRA0 18 +Endopeptidase activity 0.5445695047607367 3.168755492194062 0.001530931271773 0.8876698414154189 0.0186721275625654 70 Q4J6C6,P20618,O14773,P28072,Q8TCT8,P60900,P28070,P28074,Q9BXS4,P42892,Q92542,P49721,P22695,O15484,P78536,Q9H300,Q96K76,P52888,P17655,Q9NZ08,Q93009,Q16740,Q99436,O75844 24 +Transporter activity 0.4520875184859526 2.8345040427857766 0.0045896877212261 0.9985905568334036 0.0439562709945618 217 Q9BSK2,Q86VD7,O15118,Q8WTV0,Q6NT16,Q96H78,Q8IXU6,O43772,Q01650,Q7L0J3,Q9H813,O75027,P39210,Q7KZN9,P11166,P21796,Q8N4V1,O95563,Q70HW3,Q9NWR8,Q9UBX3,Q9Y487,O43676,P53985,P16615,O75251,O14678,Q6P4Q7,Q8NHS3,Q9HD20,P30825,P03886,O15173,P00846,P45880,Q93050,O75964,P41440,Q9Y6M7,Q9H4L5,Q13423,P25705,O43681,O75380 44 +Serine hydrolase activity 0.7071204148204736 2.8015429910639864 0.0050858864192633 0.9993081063491732 0.0480633107303892 22 Q9H3G5,Q9HB40,P42785,Q4J6C6,O75976,Q6PIU2,Q16740,O14773,P10619 9 +Peptide receptor activity 0.989837956605328 2.6662252338263337 0.0076708281838824 0.999983104635188 0.0663410413236377 2 Q99720 1 +Anion transmembrane transporter activity 0.5179769156561261 2.6323732433504663 0.0084790656030746 0.9999947180499557 0.0707239197936105 57 Q86VD7,Q14728,Q01650,Q9H813,Q9HC21,Q9Y619,Q9Y666,P11166,P21796,O00400,O95563,Q9UBX3,Q9BQT8,P53985,Q8TB61,Q15758,P30825,P55011,Q9H2D1,P45880,P51790,P51798,P41440,Q9Y6M7,O43681 25 +5 3 exodeoxyribonuclease activity 0.9810491623180442 2.630555819409903 0.0085245369337778 0.999995052653484 0.0707239197936105 2 Q9UQ84 1 +Lipid binding 0.4138488606163156 2.608249537907955 0.0091006584248858 0.9999978414935834 0.0737877248426823 157 Q14108,O15118,Q8WTV0,O94788,O14773,Q9UM22,O00291,Q8NCC3,P11717,P21796,Q06481,P28070,A6NIH7,P07602,P50897,O15173,Q96RU3,P45880,Q9Y4G8,O15254,Q9H4L5,Q15075,P61916,Q9Y5X1,Q53T59,Q01082,Q9NS86,O95219,Q9NWW5,Q6ZVM7 30 +N acetyllactosamine synthase activity 0.9689645701730294 2.5812851549829428 0.0098433238508726 0.9999992595531 0.0789124895235686 2 O60512 1 +Signaling receptor regulator activity 0.6648885681146111 2.574594925710308 0.0100357543748448 0.9999994389002024 0.0795081030526904 23 P49354,P22466,P43490,P14174,Q15375,P30533,Q9UMX5,P05067 8 +Exopeptidase activity 0.5859504658060057 2.572909071734808 0.0100847699036699 0.9999994771770888 0.0795081030526904 34 Q9H3G5,Q9HB40,P42785,Q9UIQ6,Q9NZ08,O75976,O14773,Q9NQH7,O75844,P10619,P55786 11 +Galactoside binding 0.9563306783850588 2.529495901616648 0.0114226508042212 0.9999999241063684 0.0865219045910987 2 P06280 1 +Galactosidase activity 0.9563306783850588 2.529495901616648 0.0114226508042212 0.9999999241063684 0.0865219045910987 2 P06280 1 +Isoprenoid binding 0.9560560285635802 2.528366881041412 0.011459453376116 0.9999999280329988 0.0865219045910987 2 O94788 1 +Threonine type endopeptidase activity 0.8781082600579835 2.5035869349846447 0.0122941472916477 0.9999999784412272 0.0909002496641523 8 P28074,P20618,P28072,Q99436,P49721 5 +Threonine type peptidase activity 0.8781082600579835 2.5035869349846447 0.0122941472916477 0.9999999784412272 0.0909002496641523 8 P28074,P20618,P28072,Q99436,P49721 5 +Ceramide binding 0.9524494490188375 2.4815891606573257 0.0130797983298076 0.999999993074209 0.0957172934186437 6 P21796,P07602,Q9UM22 3 +Sphingolipid binding 0.8962406029262449 2.456421118203053 0.0140328606163895 0.9999999982553708 0.1006275984903912 7 P21796,P07602,Q9UM22 3 +Phospholipid binding 0.4529704682199673 2.45365604367249 0.0141412170279222 0.9999999985086108 0.1008975834942253 106 Q92538,Q13045,Q14108,Q8WTV0,Q9H1P3,O14773,Q9UM22,O00291,Q8NCC3,Q9Y5X2,O60313,P21796,Q06481,Q96L92,P20073,P07602,P50897,P45880,Q9Y4G8,O14523,O60749,Q15075,Q9Y5X1,Q53T59,Q01082,Q9NS86,O95219,Q9NWW5,Q6ZVM7 29 +Interleukin 6 receptor binding 0.9357319417742376 2.44444583444924 0.0145074863469001 0.9999999991223908 0.102995935408092 2 P78536 1 +Organic anion transmembrane transporter activity 0.5565568157334466 2.4223871418848657 0.0154189142963765 0.999999999765645 0.1083881315316715 37 P11166,Q86VD7,Q14728,O00400,O95563,Q9UBX3,Q9H2D1,P41440,Q9BQT8,P53985,Q8TB61,Q01650,Q15758,P30825,Q9HC21,Q9Y619,Q9Y6M7 17 +Tetrapyrrole binding 0.6380027863560572 2.408937900920556 0.0159990199979553 0.9999999998989298 0.111545695115165 23 Q16850,O15173,P30519,O43169,Q8WUJ1,Q9NUN5 6 +Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity 0.9189783026641024 2.374715143654147 0.0175624979271362 0.9999999999895496 0.1182154931227521 2 O43505 1 +Beta 1 3 galactosyltransferase activity 0.9189783026641024 2.374715143654147 0.0175624979271362 0.9999999999895496 0.1182154931227521 2 O43505 1 +Pdz domain binding 0.6646343324440684 2.342349186339842 0.019162776886481 0.9999999999989796 0.1253767034407404 17 Q9BY67,P51790,Q9Y4G8,Q9UBI6,P78536,Q9UQB8 6 +Serine type exopeptidase activity 0.8647810810785005 2.3280951554281746 0.0199070514991175 0.9999999999996544 0.1291243749510942 7 Q9H3G5,Q9HB40,P42785,O75976,P10619 5 +Protease binding 0.5581013096049072 2.3041592990294024 0.0212137030089223 0.9999999999999484 0.1339779628718252 33 P46379,P07602,O75251,P14174,P25705,O75955,P41440 7 +Hydrolase activity acting on glycosyl bonds 0.5735366150723257 2.3040710729852028 0.0212186542459933 0.9999999999999488 0.1339779628718252 31 P16278,P23396,O00754,P04066,Q9BTY2,O60476,P08236,P10253,O60502,P54802,O75503,P06280,P29372 13 +Abc type transporter activity 0.7451700535172239 2.2947548922152117 0.0217471750422855 0.9999999999999764 0.1365876547589584 12 O14678,O75027 2 +Pattern recognition receptor activity 0.8904147212304281 2.2546899383624703 0.0241527976536848 0.9999999999999992 0.1454263386152247 2 Q8WTV0 1 +Scaffold protein binding 0.6081030391985561 2.199380916705465 0.0278508484049013 1.0 0.1605295083111667 22 Q9UQB8,P12956,P07602 3 +Carboxypeptidase activity 0.7318445996970172 2.176050895900084 0.0295514550572459 1.0 0.1649985514156184 11 Q9HB40,P42785,O75976,P10619 4 +Antigen binding 0.7716556506175517 2.1752794622987097 0.0296091806057916 1.0 0.1649985514156184 9 P30511,P10321,Q15392,Q01650 4 +Glycolipid binding 0.7273024353154576 2.1540915379672865 0.0312329940243829 1.0 0.1659684210381573 11 Q9NWW5,P07602,Q9UM22,P50897 4 +Ion transmembrane transporter activity 0.4079574259738909 2.14424936784769 0.0320129113664922 1.0 0.1673348883515911 124 Q14728,Q86VD7,Q9HC07,O43772,Q01650,Q9H813,Q9HC21,Q9Y619,Q9Y666,Q7KZN9,Q8N1S5,P11166,P21796,O00400,Q8N4V1,O95563,Q70HW3,Q9UBX3,Q9NWR8,Q9Y487,Q9BQT8,P53985,Q8TB61,P16615,Q6P4Q7,Q9HD20,Q15758,P30825,P00403,P20674,P55011,Q9H2D1,P00846,P45880,P51790,Q6P4A7,Q93050,O75964,P51798,P41440,P08195,Q9Y6M7,Q13423,P25705,O43681 45 +Retromer complex binding 0.9058800827474632 2.138571274848515 0.0324704059739788 1.0 0.1682636012148087 5 Q99523,P20645 2 +Serine type carboxypeptidase activity 0.904343045629459 2.1326082847369396 0.0329568731354554 1.0 0.1687121259570923 5 Q9HB40,P42785,O75976,P10619 4 +Monooxygenase activity 0.7621778771395104 2.132341204929814 0.0329788070030121 1.0 0.1687121259570923 9 Q16850,P30519 2 +Galactosyltransferase activity 0.816703484308309 2.1282704890081643 0.0333146634254855 1.0 0.1695330426215472 7 P15291,O60512,O43505 3 +Sphingosine n acyltransferase activity 0.8580060422960696 2.11680381743659 0.0342765012446455 1.0 0.1726309399604949 2 Q96G23 1 +Peptide antigen binding 0.7872370414895519 2.1158587414057632 0.0343568233698532 1.0 0.1726309399604949 8 P30511,P10321,Q15392,Q01650 4 +Azole transmembrane transporter activity 0.8527876956879942 2.0944370596539987 0.0362210643565594 1.0 0.178849338535676 2 P30825 1 +Hydrolase activity hydrolyzing o glycosyl compounds 0.589356411726626 2.0806993698532428 0.0374614318016131 1.0 0.1830735040441845 22 P16278,O00754,P04066,Q9BTY2,O60476,P08236,P10253,O60502,P54802,P06280 10 +Fad binding 0.7118713444193218 2.079089388740889 0.0376091352325709 1.0 0.1831680408767191 11 O00116,Q8NB78,Q15392,O95831,O15254 5 +Growth factor receptor binding 0.593972478969019 2.0734332163461393 0.0381319803353636 1.0 0.185082775301238 20 Q9NZ08,O95219,Q9H2J4,O00291,P78536,Q92542,P05067 7 +Microtubule minus end binding 0.7997851907959532 2.0568973939082222 0.0396960967283792 1.0 0.1913727365925581 7 Q9H6D7,Q96CW5 2 +Ganglioside binding 0.9452993505230468 2.05202059722536 0.0401676607249883 1.0 0.1923464827334173 3 Q9UM22 1 +Glycosphingolipid binding 0.9452993505230468 2.05202059722536 0.0401676607249883 1.0 0.1923464827334173 3 Q9UM22 1 +Amide binding 0.407860249362719 2.046000945893535 0.0407562776110037 1.0 0.1938303731440409 118 P21796,P07602,Q9NQX7,Q8WTV0,Q9UIQ6,P30511,Q15392,P45880,P42892,Q9UM22,P41440,P55786 12 +Cytokine activity 0.8417338149778305 2.0439325797013965 0.0409602080559432 1.0 0.1938303731440409 6 P14174 1 +Glycosaminoglycan binding 0.593996777363217 2.0433190618069768 0.0410208638328664 1.0 0.1938303731440409 18 Q06481,P15586,P30533,P10586,P05067 5 +Heparin binding 0.6826787059884755 2.038786273254343 0.0414713628815917 1.0 0.1953123261783212 13 P05067,Q06481 2 +Single stranded dna exodeoxyribonuclease activity 0.9167255185590436 2.033294627175259 0.0420227656748122 1.0 0.1972581796643323 4 Q9UQ84 1 +Organic acid transmembrane transporter activity 0.5741642605335242 2.024448188601016 0.0429240578196581 1.0 0.1986968361327219 24 O95563,Q9H2D1,Q9UBX3,P41440,Q96H78,Q9BQT8,P53985,Q01650,Q15758,P30825,Q9Y619 11 +Zinc ion binding 0.3741247393670142 2.023695831028095 0.0430014578116229 1.0 0.1986968361327219 155 Q8NB78,O15344,Q14527,Q9HD42,Q9Y2K7,Q8NCC3,Q8N8N7,Q00796,P55786,P19474,Q9UIQ6,P42892,P00813,O75592,Q13049,O75976,O60858,Q9NZ08,Q15437,Q9UPT9,Q9UBW7 21 +Beta 2 microglobulin binding 0.8357594067563819 2.0211428864990166 0.0432649759348453 1.0 0.1986968361327219 2 P30511 1 +Metallopeptidase activity 0.4823599938916778 2.008683154248805 0.0445707463520064 1.0 0.2032027317709685 44 P22695,P52888,Q9HD42,Q9UIQ6,Q9NZ08,O75976,P42892,P78536,Q9NQH7,O75844,P55786 11 +Ionotropic glutamate receptor binding 0.8663926499198744 1.9842380950813368 0.0472293036065136 1.0 0.2132791653370095 5 P41440 1 +Phosphatidylcholine binding 0.6995301900628071 1.97237567650121 0.048566736417654 1.0 0.2186269175646447 10 P21796,P45880 2 +Phosphatidylserine binding 0.6988168162719106 1.9689311521423043 0.0489609976595155 1.0 0.2197086278620399 10 Q8WTV0,Q06481 2 +Potassium chloride symporter activity 0.8170832188959074 1.94023066607398 0.052351663226561 1.0 0.2298640720747772 2 P55011 1 +Ammonium transmembrane transporter activity 0.8170832188959074 1.94023066607398 0.052351663226561 1.0 0.2298640720747772 2 P55011 1 +Cation chloride symporter activity 0.8170832188959074 1.94023066607398 0.052351663226561 1.0 0.2298640720747772 2 P55011 1 +Wide pore channel activity 0.8543566236170984 1.9367353065815631 0.0527777075623627 1.0 0.2306151560635462 5 P21796 1 +Scavenger receptor activity 0.8909040945314486 1.934433142734655 0.0530598948161613 1.0 0.2306151560635462 4 Q8WTV0,Q14108,Q08380 3 +G protein alpha subunit binding 0.890273754704378 1.9320087928081364 0.0533584206153365 1.0 0.2307347461154099 4 Q02818,P80303 2 +Heme transmembrane transporter activity 0.9132431477604354 1.930278375561177 0.0535723549366431 1.0 0.2309599712827485 3 O75027 1 +O acyltransferase activity 0.644586255077917 1.924711328481087 0.0542654824584978 1.0 0.2319269575054548 14 P23786,Q8NCC3,Q9HCL2 3 +Cyclic nucleotide binding 0.8468857436541997 1.9071452153299695 0.0565017854903082 1.0 0.2357545260078067 5 Q9Y4G8 1 +Histone methyltransferase activity h4 k20 specific 0.8071958253227087 1.897181850260235 0.0578039414182662 1.0 0.2385016874969673 2 O96028 1 +Transmembrane receptor protein tyrosine kinase activity 0.8811595106014437 1.896897497459226 0.0578414678157519 1.0 0.2385016874969673 4 P11717,Q9NWH9 2 +Transmembrane receptor protein kinase activity 0.8811595106014437 1.896897497459226 0.0578414678157519 1.0 0.2385016874969673 4 P11717,Q9NWH9 2 +Folic acid transmembrane transporter activity 0.8058225762153205 1.8911915816353 0.058598774708551 1.0 0.2402886537617882 2 P41440 1 +Serine type endopeptidase inhibitor activity 0.7354671764258713 1.8873555510140037 0.0591125193508181 1.0 0.2416294672747454 8 P05067 1 +Arylsulfatase activity 0.801977478714634 1.874404495053002 0.0608746944154319 1.0 0.2474877177516277 2 O43681 1 +L leucine transmembrane transporter activity 0.7997802801428131 1.8648024869602189 0.0622090945851834 1.0 0.2500630365438218 2 Q01650 1 +1 phosphatidylinositol binding 0.795782379456023 1.856223754152924 0.0634216716138922 1.0 0.2528651984447693 6 Q8WTV0,Q9Y5X1 2 +Cargo receptor activity 0.7022270386922336 1.8561105639401816 0.0634378003106008 1.0 0.2528651984447693 9 Q14108,Q08380,Q8WTV0,P02786,O15260,Q5KU26 6 +Microfilament motor activity 0.7264238773886875 1.8469010153320995 0.0647614875711375 1.0 0.2552890684088764 8 P35579,P35580 2 +Lysophosphatidic acid binding 0.8892857142857149 1.8384809576589185 0.0659915653050742 1.0 0.2577399549303158 3 P50897,Q9NWW5 2 +Vitamin transmembrane transporter activity 0.7229327826778004 1.8312428042014033 0.0670643104073331 1.0 0.2603441072872973 8 P11166,Q9H2D1,Q9HC21,O14678,P04062,P41440 6 +Metalloendopeptidase activity 0.6111451981166139 1.8307457945081391 0.0671384943810269 1.0 0.2603441072872973 15 P78536,O75844,P42892,P52888 4 +Calmodulin dependent protein kinase activity 0.882510807597729 1.8124032255417517 0.0699239148200863 1.0 0.2689526319360193 3 Q13555 1 +Ccr5 chemokine receptor binding 0.78439989014007 1.7974033933090954 0.0722716024362053 1.0 0.2725393662612793 2 P48681 1 +Acid phosphatase activity 0.8547646534922736 1.7946335945976266 0.0727120969860757 1.0 0.272600754862607 4 Q9NPH0 1 +Porin activity 0.8545283315463459 1.7937142338709169 0.0728587922315089 1.0 0.272600754862607 4 P21796 1 +Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen 0.4958665672111659 1.780565640321591 0.0749834371089444 1.0 0.2770437616603096 32 Q8NB78,Q9Y2K7,Q16850,P30519 4 +Oxidoreductase activity acting on the ch nh2 group of donors 0.7800054929964282 1.7780892075399677 0.0753892047037956 1.0 0.2770437616603096 2 P23378 1 +G protein coupled receptor activity 0.850475937185017 1.7779392592044363 0.0754138314266272 1.0 0.2770437616603096 4 Q99720,P22466 2 +Iron ion binding 0.5368055919588094 1.776587533041785 0.0756361283355226 1.0 0.2770437616603096 24 P22830 1 +5 3 exonuclease activity 0.7106780670245768 1.7761012224702757 0.0757162347915352 1.0 0.2770437616603096 8 Q9UQ84 1 +Organic cation transmembrane transporter activity 0.7737043369461835 1.7648741221518016 0.0775849237369668 1.0 0.2802878130953206 6 Q86VD7,Q70HW3,O43772 3 +Double stranded rna adenosine deaminase activity 0.7747871463883532 1.7551220762940445 0.0792384289383978 1.0 0.2815175383532322 2 Q9NZI8 1 +Aromatic amino acid transmembrane transporter activity 0.8676155329672454 1.7548959067633427 0.0792771144528159 1.0 0.2815175383532322 3 P30825 1 +Mannose binding 0.7185258577482272 1.7068569562248106 0.0878486429734062 1.0 0.2970616434195514 7 O75503 1 +Lipopolysaccharide binding 0.7594930425065957 1.7057056312777346 0.0880629006768611 1.0 0.2970821732053922 6 Q8WTV0 1 +Vitamin d binding 0.7613293051359497 1.695740982443777 0.0899349435998526 1.0 0.3014633221423751 2 P04062 1 +Cytokine receptor binding 0.5205859188243078 1.6868274346119192 0.0916365385494588 1.0 0.3062420152460838 25 Q8WUH2,Q9NZ08,P14174,Q9H2J4,P78536 5 +Lipid kinase activity 0.7525405108486625 1.656852775429982 0.0975492440233196 1.0 0.3229499326453832 2 Q9NRA0 1 +Nucleobase containing compound transmembrane transporter activity 0.5311765749807879 1.6509010322167943 0.0987587850317444 1.0 0.3229499326453832 18 Q9BSK2,O00400,Q86VD7,P51991,Q8TB61,Q9HC21,P41440 7 +Structural constituent of muscle 0.7454627453946108 1.6470272933454846 0.099552435980446 1.0 0.3229499326453832 6 P67936,P09493 2 +Phosphatidic acid binding 0.8395760098568859 1.6460486267757442 0.0997537480101034 1.0 0.3229499326453832 3 Q9Y4G8 1 +Quinone binding 0.7422467810995333 1.6335424086400667 0.1023549690234881 1.0 0.3282259343741969 6 Q9Y6N5,Q8N0U8,O75251 3 +Transcription elongation regulator activity 0.7462235649546805 1.6288532788792156 0.10334408269255 1.0 0.3285005613669231 2 O14776 1 +Quaternary ammonium group binding 0.5747025292967383 1.6247165620995496 0.1042229667061642 1.0 0.3293588574241997 15 P21796,P45880 2 +Transition metal ion binding 0.3707427741621969 1.6108633149631495 0.1072095173542093 1.0 0.3353318161961909 212 P22830,Q8NB78,O15344,Q14527,Q9HD42,Q9Y2K7,Q8NCC3,P05067,Q8N8N7,Q00796,P55786,P19474,Q06481,Q9UIQ6,P42892,P00813,O75592,Q13049,Q16850,O75976,O60858,Q9NZ08,Q15437,P15291,Q9UPT9,Q9UBW7 26 +Acyltransferase activity 0.4097125454823276 1.6032071493114537 0.1088889275950031 1.0 0.3392668000570211 59 Q9HCL2,Q8NCC3,Q9BWD1,Q9UPT9,Q96G23,Q6N069 6 +Sterol binding 0.5219052606265059 1.6021318241678857 0.109126461966484 1.0 0.3392668000570211 19 Q9H4L5,P21796,Q14108,O15118,P45880 5 +Signaling receptor binding 0.3665456705277808 1.600609704464475 0.1094633915036824 1.0 0.3395744775559888 202 P07942,P46379,Q8WUH2,Q92896,P30511,P14174,O00291,Q92888,Q9UMX5,P06280,P05067,P46939,P35579,P22466,Q9BY67,Q96JJ3,Q15375,Q9H2J4,Q92542,O14936,P12814,P43490,Q8WXW3,O43707,Q9Y4G8,P30533,P08236,Q13573,Q9NPF0,P78536,P41440,Q9NUQ9,P49354,Q9NZ08,P25705,O95219,O75955,Q9NUN5 38 +Steroid binding 0.5089053721733023 1.5879284108622138 0.1123025282015826 1.0 0.3456806355626624 24 Q9H4L5,P21796,Q14108,O15118,O15173,P45880 6 +Hydrolase activity acting on ether bonds 0.6909712015866489 1.585720915719241 0.1128026323791231 1.0 0.3461706589355026 7 P07099 1 +Inorganic anion transmembrane transporter activity 0.500790763672659 1.580313993146322 0.1140349768657069 1.0 0.3464019784631401 26 P21796,P55011,Q9UBX3,P45880,P51790,Q9H813,O43681,Q9Y6M7 8 +Modified amino acid binding 0.51197738563302 1.575861373128437 0.1150577546069788 1.0 0.3485932395417385 22 Q8WTV0,P41440,Q06481 3 +Organophosphate ester transmembrane transporter activity 0.5507344168591186 1.5735488626195762 0.1155917834692421 1.0 0.3487303911429356 16 Q9BSK2,O00400,Q86VD7,Q8TB61,Q9HC21,P41440 6 +Nucleotide transmembrane transporter activity 0.5507344168591186 1.5735488626195762 0.1155917834692421 1.0 0.3487303911429356 16 Q9BSK2,O00400,Q86VD7,Q8TB61,Q9HC21,P41440 6 +Carboxylic acid binding 0.4457662087676944 1.5687002438058073 0.1167178017769166 1.0 0.3499081998648319 39 P11717,P07602,Q9UM22,O15254,P41440 5 +Catalytic activity acting on a glycoprotein 0.8192748537431347 1.5668220587440709 0.1171562898204741 1.0 0.3504864267794896 3 O43505 1 +Demethylase activity 0.6160095183665899 1.5613158059566532 0.1184492560464907 1.0 0.3514076681462416 10 Q8NB78,Q16850 2 +Hsp70 protein binding 0.5470929064575776 1.551938455061964 0.1206769504530782 1.0 0.3560882486987858 16 P23396,P46379,Q99543,P02786,Q9NXW2,Q8IXB1 6 +G quadruplex rna binding 0.7278220269156797 1.5470861190181415 0.1218424806701783 1.0 0.3584932369409164 2 Q9H2U1 1 +Flavin adenine dinucleotide binding 0.4817721939309987 1.5458664241073603 0.1221368309063088 1.0 0.3586198718174955 29 O00116,Q8NB78,O15254,Q9Y6N5,Q15392,O95831,P00390,P50336 8 +Palmitoyl protein hydrolase activity 0.7567215134449528 1.5443890825965323 0.122494103251094 1.0 0.3586273272837417 5 P50897 1 +Structural constituent of postsynapse 0.7559925666934627 1.5414201815995374 0.1232145553507524 1.0 0.3592818004536319 5 P07196,P12814,Q16352 3 +Xenobiotic transmembrane transporter activity 0.755761501332169 1.5404789881060872 0.1234436406981898 1.0 0.3592818004536319 5 P41440 1 +S methyltransferase activity 0.7261741279868138 1.5397506801589098 0.1236211380677878 1.0 0.3592818004536319 2 Q99707 1 +Guanyl nucleotide exchange factor activity 0.4437240778208816 1.5320879084485095 0.125500743152501 1.0 0.3624360002307319 38 Q92538,Q02818,Q9NZM3,O75592,Q96N67,A4D1U4,Q9Y4G8,Q9HCU5,Q14185,Q92888,P11274,P80303,P49770 13 +Signaling receptor inhibitor activity 0.7242515792364703 1.531190294884835 0.1257223686855026 1.0 0.3624360002307319 2 P30533 1 +L amino acid transmembrane transporter activity 0.6323739030097084 1.5250802392339688 0.1272390853485228 1.0 0.3660689007910121 9 Q01650,Q15758,P30825,Q9Y619,P08195,Q9UJS0 6 +Pentosyltransferase activity 0.5570332432518931 1.523581269209534 0.1276133451258192 1.0 0.3664069285604508 15 Q13126 1 +Proteasome binding 0.5996928050253091 1.5165076415061811 0.1293910395670487 1.0 0.370765087273451 11 P46379 1 +Tap binding 0.7131809789702467 1.5111348523737886 0.1307540965819433 1.0 0.3739200317082829 6 P30511,P10321 2 +Sulfuric ester hydrolase activity 0.8021978021978027 1.4999576500058216 0.1336253730250041 1.0 0.378340093862462 3 P15586,O43681 2 +Insulin receptor binding 0.6495057780957543 1.4971407200769646 0.1343566462234333 1.0 0.379447145584096 8 O60749,Q9NUN5,O95219 3 +Branched chain amino acid transmembrane transporter activity 0.8000000000000006 1.4913401050584527 0.1358722245805099 1.0 0.3814013719736694 3 Q96H78,Q01650 2 +Cholesterol binding 0.5346940454534926 1.478118171596672 0.1393761510559601 1.0 0.3864188015465537 16 Q9H4L5,P21796,Q14108,O15118,P45880 5 +Protein homodimerization activity 0.3584933842766764 1.4778147058819755 0.139457381076717 1.0 0.3864188015465537 201 P22830,Q14108,O15344,P51114,Q9HD42,Q07820,Q15102,P14373,O75027,O00291,Q8TCT8,P06280,P16278,P35579,Q9UKU0,P19474,Q8WVQ1,Q06481,Q9BY67,P02786,Q15070,P42892,P67936,Q8TCG1,P29372,P20585,P27105,Q8N2A8,P07602,Q15046,P12814,Q8IY95,Q01664,O43707,P31350,Q9Y448,P09493,Q9BX67,O60749,P31749,Q15075,O75569,Q13555,Q9Y5X1,Q9NWU2,Q9UJC3,O95684,Q8TBA6,Q9NWW5,O00764,Q9NQH7,Q9UPN4,P23246,Q9GZY8 54 +Peptide n acetyltransferase activity 0.5617050208337766 1.4708051256109924 0.1413438258959538 1.0 0.3894508136473388 14 Q6N069 1 +Mrna 5 utr binding 0.496160708657418 1.4700694909319292 0.1415429342900365 1.0 0.3894508136473388 22 P82912,Q9NZI8,O60506,P35580,Q9Y6M1,Q9H2U1,O76021 7 +Pre mirna binding 0.7304954362004821 1.4373134716065208 0.1506289426840861 1.0 0.4063279796033854 5 O75569 1 +Transition metal ion transmembrane transporter activity 0.6549444552255864 1.42589561454919 0.1538984754924039 1.0 0.4135840386584943 7 Q9HC07,Q8N4V1,Q9HD20 3 +Gtp dependent protein binding 0.6099920269749157 1.4173481153493523 0.1563811741598728 1.0 0.4163357006084674 9 Q9BZG1,Q15075,Q86YV9 3 +Manganese ion transmembrane transporter activity 0.7554870639115798 1.403725962868142 0.160400468121971 1.0 0.4223089815683629 4 Q9HD20 1 +Dicarboxylic acid transmembrane transporter activity 0.6492620890306449 1.4005691885546354 0.161342940050462 1.0 0.4232286313456053 7 Q15758,P41440,Q9BQT8,Q9UBX3 4 +Rage receptor binding 0.6940400988739317 1.396415997127483 0.162589260569224 1.0 0.4244617213903519 2 P26583 1 +Phosphatidylinositol 3 phosphate binding 0.6274064779746518 1.3951321519606266 0.1629759921912446 1.0 0.4244617213903519 8 Q96L92,Q9NS86,O95219,O00291 4 +Adenosine deaminase activity 0.7750000000000006 1.3931715473126205 0.163567921553414 1.0 0.4251574208683458 3 P00813,Q9NZI8 2 +Mhc protein binding 0.5819162999865961 1.3897144653915396 0.1646156004592294 1.0 0.4255551845205079 10 Q9NUQ9 1 +2 acylglycerol 3 phosphate o acyltransferase activity 0.7737756348314602 1.3883586932953955 0.1650278479162343 1.0 0.4258494375704637 3 Q96N66 1 +Guanylate kinase activity 0.7505086978873685 1.3839476045819412 0.1663744987565805 1.0 0.428549476039062 4 Q14168 1 +Alcohol binding 0.4886152354347025 1.3776376975274809 0.1683151758420278 1.0 0.4312132063313711 18 Q9H4L5,P21796,Q14108,O15118,P45880 5 +Peptide binding 0.3734409064657864 1.3718159514070074 0.1701207402251112 1.0 0.4335041005379174 84 Q9Y3C6,P10321,Q8WTV0,Q9UIQ6,Q9NZ08,P30511,Q15392,Q01650,P30533,P42892,Q13427,P04439,O14773,O14523,Q9NQX7,P24390,O00410,P55786 18 +Histone methyltransferase activity h3 k36 specific 0.7689560439560444 1.36941058390896 0.17087096770805 1.0 0.4346396986085336 3 O96028,Q96L73 2 +Acylglycerol o acyltransferase activity 0.6414641035124166 1.3657735554306585 0.1720100490403358 1.0 0.4367586120650519 7 Q96N66,Q8NCC3 2 +Phosphatidylinositol 3 4 bisphosphate binding 0.7666797862033036 1.3604602727907291 0.1736843163454651 1.0 0.4394459564272672 3 O00291 1 +Calcium ion binding 0.3700991724375932 1.3496882931581695 0.1771159890741211 1.0 0.4466175871612129 93 Q9BQT9,O60476,Q9UM22,Q14257,Q8WVQ1,O75071,P16615,Q9BPX6,P67936,O75592,Q13813,Q02818,P12814,Q9NZM3,P61201,O43707,Q9Y4G8,Q9NPF0,Q9H223,P80303,Q9BRK5,Q9Y680,O43681,Q8IYU8 24 +Amino acid transmembrane transporter activity 0.5564904230352993 1.3298999659897293 0.183551232641892 1.0 0.456319876271742 12 Q96H78,Q01650,Q15758,P30825,Q9Y619 5 +Double stranded rna binding 0.4251288968695187 1.3288282517662404 0.1839046391376997 1.0 0.4564033392165174 35 Q9NZI8,P12814,P26038,Q15056,O75569,P02786,P08670,P23588,Q9H2U1,Q9NY93,P08195,Q8WYQ5 12 +Amide transmembrane transporter activity 0.6319155594417072 1.3231145378050568 0.1857972908196024 1.0 0.4595021386474395 7 O00400,O15439,Q9H2D1,P41440 4 +Thyroid hormone receptor binding 0.5898039791977432 1.3197064523148303 0.1869330449405404 1.0 0.4602528996574326 9 Q9NVC6,Q9NPJ6,Q15648,Q9Y2W1,Q96L73 5 +Peptide hormone binding 0.7542125250294769 1.311432489347874 0.1897116882977494 1.0 0.4623662910671353 3 P42892 1 +Atpase coupled transmembrane transporter activity 0.4500949727536045 1.310802219158616 0.1899245926256947 1.0 0.4623662910671353 29 O14678,P16615,O75027 3 +Phosphoric diester hydrolase activity 0.5596465990414877 1.3097564520872007 0.1902782394154913 1.0 0.4623662910671353 11 Q8N2A8 1 +Lys63 specific deubiquitinase activity 0.6742653117275429 1.308087744715314 0.1908435497116627 1.0 0.4623662910671353 2 O95630 1 +Kinetochore binding 0.6643830112418967 1.304017441211092 0.1922276357400432 1.0 0.4649302308492231 6 Q96EA4,Q9H3R5 2 +Immunoglobulin binding 0.672617412798677 1.3007289567736993 0.193351246943946 1.0 0.466067955049005 2 P17931 1 +Acetylcholine receptor binding 0.672617412798677 1.3007289567736993 0.193351246943946 1.0 0.466067955049005 2 O15258 1 +Sulfur compound transmembrane transporter activity 0.6057867170953654 1.294936468106436 0.1953421468492919 1.0 0.4692815548046121 8 Q9HC21,Q70HW3,Q9UBX3,Q8TB61 4 +Supercoiled dna binding 0.6946124244090068 1.290208403817468 0.1969783090836454 1.0 0.4724168858190958 5 P23396,P26583,P11387,O75475 4 +Cation transmembrane transporter activity 0.3663999103852413 1.2889112821572832 0.1974289313224986 1.0 0.4727031627469891 85 Q86VD7,Q9HC07,O43772,Q01650,Q9HC21,Q9Y619,Q9Y666,Q7KZN9,Q8N1S5,O00400,Q8N4V1,Q70HW3,Q9Y487,P16615,Q6P4Q7,Q9HD20,Q15758,P30825,P00403,P20674,P55011,P00846,P51790,Q93050,O75964,P08195,Q9Y6M7,Q13423,P25705 29 +Metalloexopeptidase activity 0.4687933146770951 1.2855487786692807 0.1986005826719596 1.0 0.4739181128309138 22 Q9UIQ6,Q9NZ08,O75976,Q9NQH7,O75844,P55786 6 +Structural constituent of cytoskeleton 0.4195332672089967 1.2825821709109892 0.1996384998012206 1.0 0.474806898693903 35 P07197,P26038,Q96CW5,P08670,Q01082,O00291,P09493,Q13813,P07196,Q9UEY8 10 +Metal cluster binding 0.4134543478056518 1.259864547468364 0.2077182298738431 1.0 0.4875228849177206 37 P22830,Q9NZ45,P23396,Q9Y5Y2,P80404,O75251 6 +Vitamin d receptor binding 0.6169740580362604 1.2562831537696386 0.209013327498265 1.0 0.4887734309229765 7 Q9NPJ6,Q13573,Q9Y2W1 3 +Clathrin heavy chain binding 0.6530002922565525 1.2555515610500805 0.2092786028689128 1.0 0.4887734309229765 6 Q5VW38 1 +Phosphatidylinositol binding 0.3669940150252211 1.2480016246143537 0.2120304622418429 1.0 0.4935847791502608 67 Q92538,Q13045,Q15075,Q06481,Q8WTV0,Q9Y5X1,Q53T59,Q9H1P3,Q96L92,Q9NS86,O14523,O00291,O95219,Q6ZVM7,O60749,Q9Y5X2 16 +Atpase binding 0.4406823184982341 1.2405160338234351 0.2147845874266596 1.0 0.4959508191874487 29 Q9Y487,Q93050,Q16740,Q8IXB1,P55769 5 +Protein self association 0.5079233216313245 1.2393294669229769 0.2152235103939044 1.0 0.4961614690340898 15 Q9Y282,Q13049 2 +Magnesium ion transmembrane transporter activity 0.6780456783057096 1.222217196162678 0.2216255026124232 1.0 0.5042570356079077 5 Q8N4V1 1 +Anion cation symporter activity 0.7313186813186822 1.2214504913313673 0.2219154999031296 1.0 0.5042570356079077 3 P55011,Q9Y666 2 +Rna polymerase i transcription regulatory region sequence specific dna binding 0.7081615828524328 1.2155791258434614 0.2241452898850777 1.0 0.5084837414205294 4 Q12824,Q9UIF9,P17480 3 +Solute cation antiporter activity 0.7224661391656786 1.1867073279429696 0.2353430835569767 1.0 0.5288295464272796 3 P51790 1 +Protein carboxyl o methyltransferase activity 0.7222393960090214 1.1858180096555189 0.2356941776648562 1.0 0.5288295464272796 3 O60725 1 +Monocarboxylic acid transmembrane transporter activity 0.6675349462480786 1.1791073747431138 0.2383554223860868 1.0 0.5315856310295469 5 P53985 1 +Phosphatidylinositol 4 5 bisphosphate phosphatase activity 0.6989423457581194 1.1789637353202589 0.2384126165794744 1.0 0.5315856310295469 4 Q8WUK0,Q96PE3 2 +Phosphatidylinositol bisphosphate phosphatase activity 0.6989423457581194 1.1789637353202589 0.2384126165794744 1.0 0.5315856310295469 4 Q8WUK0,Q96PE3 2 +Cyclin binding 0.5327998369235586 1.1703227449516838 0.2418711120532921 1.0 0.5351163982946479 11 P11802,P06493,P12956,O14976,Q9ULV3,P24941 6 +Microtubule binding 0.3555075600508333 1.163974701009989 0.2444342644594017 1.0 0.5391154488154039 90 O15344,Q8NBT2,Q9Y496,Q9H6D7,O60313,Q9UH99,Q96CW5,Q08379,Q14203,Q96ED9,Q9NXR1,P29372,P33176,P23396,O15078,Q9UQ16,P52732,Q9Y448,O95239,P07197,Q15691,Q15555,P49354,Q86VS8,Q9UJC3,Q9HC35,O43663,Q9BSJ2 28 +Dynein light intermediate chain binding 0.5771850399753612 1.1621249468515389 0.2451847153948225 1.0 0.5399360939327342 8 Q9UJC3,Q96ED9,Q8TD16 3 +Camp dependent protein kinase regulator activity 0.7154601507373446 1.159244458946776 0.2463565539953225 1.0 0.5416807435305474 3 P54619 1 +Fucosyltransferase activity 0.6388354847569295 1.150200328613861 0.2500613709238335 1.0 0.5481375980158378 2 Q9Y2G5 1 +Voltage gated anion channel activity 0.5736210774408508 1.1455805604694922 0.2519687445140899 1.0 0.5497850128770738 8 P21796,P45880,P51790 3 +Growth factor binding 0.4912274834542989 1.1420971353893603 0.2534136460477358 1.0 0.5520935464276627 15 Q92896,P11717,Q99523 3 +Rna strand annealing activity 0.6582188821883947 1.1409376942869711 0.2538958518602592 1.0 0.5523008850679724 5 P51114,P23588,Q15056 3 +Oxidized dna binding 0.5909174580485639 1.1396993355516774 0.2544115840868697 1.0 0.5525804117077063 7 P20585 1 +Misfolded protein binding 0.4904549424695232 1.137596748803008 0.255288904845464 1.0 0.5536432632438864 15 P46379 1 +Histone deacetylase regulator activity 0.6336171381488547 1.12704114526228 0.2597250851682369 1.0 0.5590161335370649 2 Q86XI2 1 +Cullin family protein binding 0.5685859578277761 1.1222164318128605 0.2617704277405304 1.0 0.5606222519699797 8 Q92564,Q4G0X4 2 +Cobalamin binding 0.6518154401331284 1.1147332609199283 0.2649647433569191 1.0 0.5659810067935459 5 Q9NUN5,Q9NPF0 2 +Calmodulin binding 0.3835401925256246 1.1034749925457668 0.2698209456240097 1.0 0.5712677884354034 43 P35579,Q14012,Q15051,P35580,Q15075,Q9UEY8,Q13555,Q86VI3,Q7Z406,Q01082,P32929,Q13813,P31749,O14936 14 +Active transmembrane transporter activity 0.3499292561947328 1.0960890430123114 0.2730398091787651 1.0 0.5763668192236919 90 P03886,P55011,Q9UBX3,O43676,P53985,P16615,Q01650,O14678,O75251,P51790,Q9HD20,O75027,P51798,O75380,P41440,Q7KZN9,Q9Y6M7 17 +Protein tyrosine kinase activity 0.4939154818748126 1.090290777573426 0.2755850763953527 1.0 0.5791751163713819 14 P11717,P11274,Q15375,Q9NWH9 4 +Exodeoxyribonuclease activity 0.5220810092623529 1.086022374833519 0.2774690932298034 1.0 0.5818120202722489 10 Q9UQ84 1 +Glycosyltransferase activity 0.3615733220751137 1.085601782584387 0.2776552107956562 1.0 0.5818120202722489 56 Q68CQ7,Q96L58,P43490,Q16739,O43505,Q8NAT1,P15291,Q6ZXV5,Q13126,O60512,P04843,P13807 12 +Semaphorin receptor activity 0.69497676796488 1.07918980149082 0.2805031250965322 1.0 0.5845227505334262 3 Q9NWH9 1 +Inorganic molecular entity transmembrane transporter activity 0.3478360747301744 1.078506816615039 0.2808076413700371 1.0 0.5845227505334262 94 Q9HC07,Q9H813,Q7KZN9,P21796,Q8N4V1,Q9UBX3,Q9NWR8,Q9Y487,P16615,Q6P4Q7,Q9HD20,P55011,P00846,P45880,P51790,Q93050,O75964,Q9Y6M7,Q13423,P25705,O43681 21 +Hexosyltransferase activity 0.3828053281123742 1.0776880705097025 0.2811729840027703 1.0 0.5845227505334262 42 Q96L58,Q16739,O43505,Q8NAT1,P15291,Q6ZXV5,Q13126,O60512,P04843,P13807 10 +N acyltransferase activity 0.437644813241204 1.0743475609399953 0.2826669359345048 1.0 0.5862873802013641 22 Q9UPT9,Q6N069 2 +Transferrin receptor binding 0.6397102424076649 1.065291456820198 0.2867440576155062 1.0 0.5915624119541079 5 O15111,O60749,O95219 3 +Rna 2 o methyltransferase activity 0.6171381488601972 1.054173343339995 0.2918035619682446 1.0 0.5979190122297587 2 Q8IY81 1 +Mirna binding 0.5045152058350078 1.053643999777346 0.2920459365971561 1.0 0.5979190122297587 12 Q5TAX3,P98175,P22626,P43243,Q9NY93 5 +Vinculin binding 0.6038730243322914 1.046736743381513 0.2952210122324654 1.0 0.6004317876840847 6 P12814,P46939 2 +Secondary active transmembrane transporter activity 0.4275372484138606 1.0390407526542689 0.298785783537284 1.0 0.6013316139729623 25 O00400,P55011,Q9UBX3,P53985,Q01650,P51790,Q15758,P51798,P41440,Q9Y666,Q9Y6M7 11 +Structural constituent of synapse 0.5499519740850063 1.0359143547852645 0.3002421000954567 1.0 0.6013316139729623 8 P07196,Q16352,P12814,Q8IUD2 4 +Camp dependent protein kinase inhibitor activity 0.6127437517165552 1.0348243790193694 0.3007509354673354 1.0 0.6013316139729623 2 P13861 1 +N acetyltransferase activity 0.4358852592331077 1.034628209139301 0.3008425747852548 1.0 0.6013316139729623 18 Q6N069 1 +Ap 2 adaptor complex binding 0.6834846014792921 1.034484840784223 0.3009095600237181 1.0 0.6013316139729623 3 Q9NUN5 1 +Nadplus kinase activity 0.6832417582417594 1.0335421696926197 0.3013502466909652 1.0 0.6013316139729623 3 Q9NRA0,Q53H12 2 +Floppase activity 0.6121944520736 1.0324085618144156 0.3018807627536011 1.0 0.6013316139729623 2 Q96AA3 1 +Exogenous protein binding 0.4481641761835676 1.031266512858157 0.3024158573555398 1.0 0.6013316139729623 17 Q8WTV0,Q14108,O15118 3 +Double stranded methylated dna binding 0.6110958527876895 1.0275788677032414 0.3041479689317186 1.0 0.6022565864675307 2 P51608 1 +Aldehyde dehydrogenase nad p plus activity 0.547550705462305 1.0248196704776835 0.3054482831886687 1.0 0.6022565864675307 8 P30837 1 +Sulfatide binding 0.6599502118776722 1.024803771378181 0.3054557865536811 1.0 0.6022565864675307 4 P50897,Q9NWW5 2 +Cytoskeletal motor activity 0.4189707464441389 1.0236920823485165 0.3059807362955102 1.0 0.6022565864675307 27 P35579,Q9UQE7,P35580,P33176,Q9Y496,O94832,Q7Z406,Q07866,Q02241,P52732,O95239,Q14807 12 +Acidic amino acid transmembrane transporter activity 0.6807022914061984 1.023689836079039 0.3059817976096424 1.0 0.6022565864675307 3 Q15758 1 +L aspartate transmembrane transporter activity 0.6807022914061984 1.023689836079039 0.3059817976096424 1.0 0.6022565864675307 3 Q15758 1 +Protein demethylase activity 0.564337872552943 1.0211422326794504 0.3071870565834558 1.0 0.6037960464801535 7 Q8NB78 1 +Phosphatidylinositol 3 5 bisphosphate binding 0.5971320915979605 1.0182348983321874 0.3085663383512309 1.0 0.604316741434292 6 Q92538,O00291 2 +Regulatory rna binding 0.4698906778172098 1.01790642532051 0.3087224278245262 1.0 0.604316741434292 15 Q5TAX3,P98175,P22626,P43243,Q9NY93 5 +Anion channel activity 0.4687552042348754 1.0113090981931698 0.3118685128534926 1.0 0.6081999746926383 15 P21796,Q9H813,P45880,P51790 4 +Amyloid beta binding 0.4773553563970484 0.9972287662956462 0.3186534809863861 1.0 0.6153159910251327 14 Q8WTV0 1 +Metalloaminopeptidase activity 0.4869717982538082 0.992410697907082 0.3209972224912789 1.0 0.6173356286995351 13 Q9UIQ6,Q9NZ08,P55786 3 +Monocarboxylic acid binding 0.4288113325754294 0.988624521270578 0.3228468842245759 1.0 0.6183926225348589 18 O15254,P07602 2 +Aminopeptidase activity 0.450454297414576 0.9711772829511748 0.3314600042679989 1.0 0.6273122361942103 16 Q9UIQ6,Q9NZ08,P55786 3 +Phosphatidylinositol phosphate phosphatase activity 0.6110109576770913 0.9488242379009416 0.3427100122771636 1.0 0.6409530635904488 5 Q8WUK0,Q96PE3 2 +Arp2 3 complex binding 0.5796557172085278 0.9446657635741365 0.3448295410416722 1.0 0.6437868632396545 6 Q9Y6W5,Q9Y5X1 2 +Proteoglycan binding 0.6393309009665227 0.9440824721836488 0.345127505520908 1.0 0.6437868632396545 4 O94813,P10586 2 +Inositol phosphate phosphatase activity 0.6579861283212443 0.9360640784251516 0.3492401965948126 1.0 0.6463479846572713 3 Q96PE3 1 +Inositol trisphosphate phosphatase activity 0.6579861283212443 0.9360640784251516 0.3492401965948126 1.0 0.6463479846572713 3 Q96PE3 1 +Mannosidase activity 0.6076589821238209 0.9353140343290404 0.3496264847623429 1.0 0.6463479846572713 5 O00754,O60476 2 +Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor 0.4145154720699159 0.9265393104799016 0.3541657778094733 1.0 0.650443455513666 23 P30837 1 +Purine nucleotide transmembrane transporter activity 0.473783884353474 0.9210126672276772 0.3570438136059091 1.0 0.6540455995065882 13 Q86VD7,P41440,Q8TB61 3 +Smad binding 0.4415920694895203 0.9179988850073488 0.3586194495964494 1.0 0.656089685351453 16 Q13573 1 +Protein tyrosine kinase activator activity 0.5850041197473151 0.9137713128997303 0.3608370232039166 1.0 0.6584583530843849 2 Q8IZP0 1 +Integrin binding 0.4123856359337082 0.8963843881743292 0.3700475024370027 1.0 0.6692747604278869 21 P35579,P07942,P12814,O43707,P78536,Q9BX67,P46939 7 +Oxidoreductase activity acting on the aldehyde or oxo group of donors 0.4075295791924403 0.8884427667925864 0.374302629290306 1.0 0.6724698698153617 24 P30837 1 +Clathrin light chain binding 0.6453534358146195 0.8878125550198813 0.3746415882993781 1.0 0.6724698698153617 3 O00291 1 +Lrr domain binding 0.6444290937274265 0.8842978040036867 0.3765354734118831 1.0 0.6733284718781418 3 Q6P1K2 1 +Leucine zipper domain binding 0.6444290937274265 0.8842978040036867 0.3765354734118831 1.0 0.6733284718781418 3 Q6P1K2 1 +Hexosaminidase activity 0.5903591950928277 0.8659957763990171 0.3864924779713432 1.0 0.6851239330001327 5 O60502 1 +Proton transmembrane transporter activity 0.3612652415213855 0.8433618973370002 0.3990260749160081 1.0 0.6972018273550875 39 Q13423,Q9Y487,P00846,P51790,P25705,Q93050,O75964,Q7KZN9,P00403 9 +Solute sodium symporter activity 0.628983492166547 0.825929363357667 0.4088441626457308 1.0 0.7063047999002682 3 Q9Y6M7 1 +Mismatched dna binding 0.5800849353117976 0.825208134072872 0.4092534362359612 1.0 0.7063047999002682 5 P20585 1 +Annealing activity 0.4702567788720799 0.8251166430178621 0.4093053717778994 1.0 0.7063047999002682 10 P51114,Q15056,P28370 3 +Deoxyribonuclease activity 0.4030047739129437 0.8247828156785613 0.4094949044703191 1.0 0.7063047999002682 19 Q9UQ84 1 +Phosphatidylinositol phosphate 5 phosphatase activity 0.6273545256805075 0.8198164956999401 0.4123207258369237 1.0 0.7063405471420049 3 Q8WUK0 1 +Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity 0.6273545256805075 0.8198164956999401 0.4123207258369237 1.0 0.7063405471420049 3 Q8WUK0 1 +Sirna binding 0.6059371143832125 0.815348957399314 0.4148725926003485 1.0 0.7065940087550653 4 Q06787,P51608 2 +Long chain fatty acid transporter activity 0.6053092586776769 0.8129590210110235 0.4162415534633215 1.0 0.7065940087550653 4 O14678 1 +Carbohydrate derivative transmembrane transporter activity 0.4532498932143564 0.8107684525334221 0.4174986544987642 1.0 0.7065940087550653 13 Q86VD7,P41440,Q8TB61 3 +Primary active transmembrane transporter activity 0.3273488786283078 0.8103909930076024 0.4177154928711721 1.0 0.7065940087550653 67 P03886,O43676,P16615,O14678,Q9HD20,O75027,O75380,Q7KZN9 8 +Dna clamp loader activity 0.5157500197420586 0.8075293192025668 0.4193615897580063 1.0 0.7068034794689966 7 P41440 1 +Endoribonuclease activity 0.387064799081161 0.7947336951540706 0.4267684275473757 1.0 0.7138465073967114 27 Q9UQ84,Q8N2A8 2 +Oxidoreductase activity acting on a heme group of donors 0.4968009213438088 0.7931595245099183 0.4276848860947488 1.0 0.7138465073967114 8 Q7KZN9,P00403 2 +Histone deacetylase binding 0.3664174458363714 0.7684356304866266 0.4422284190144339 1.0 0.7299739912803894 32 P23246,Q8IWS0,Q01664,Q13330,Q12834,Q9UHI6,Q16513,Q9H2U1,Q4G0X4,Q14839,Q14103 11 +Gamma catenin binding 0.5931659617496493 0.7670033637945474 0.4430795155558233 1.0 0.7299739912803894 4 P35221 1 +Actin filament binding 0.321190744862179 0.7666873749565306 0.4432674117450972 1.0 0.7299739912803894 77 Q13045,Q86VI3,P06753,O00291,P46939,P35579,Q7Z406,Q9UBT7,P67936,Q13813,Q5SNT2,P12814,O43707,P09493,Q7L576,P35580,Q14331,Q6WCQ1,Q01082,Q9UEY8 20 +Tat protein binding 0.5650850442106593 0.7662810769722003 0.4435090752908883 1.0 0.7299739912803894 5 Q12824,Q13049 2 +Notch binding 0.5639137051588338 0.7617142488783969 0.4462305692077024 1.0 0.7299919321057982 5 Q13573 1 +Udp glycosyltransferase activity 0.3889505918077912 0.7615945527338928 0.4463020269555877 1.0 0.7299919321057982 24 Q96L58,Q16739,Q10472,O43505,Q8NAT1,P15291,O60512,P13807 8 +Primary mirna binding 0.5913712558395201 0.7602571747526176 0.4471008750248546 1.0 0.7299919321057982 4 Q15910,Q8WYQ5,P40763 3 +Atp dependent peptidase activity 0.5336257674430379 0.7544578073556742 0.4505743714684573 1.0 0.7348224320977013 6 Q16740 1 +Endoribonuclease activity producing 5 phosphomonoesters 0.3913967842752269 0.7477355499057946 0.4546196837303633 1.0 0.738886433579987 18 Q9UQ84 1 +Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor 0.559695020604873 0.745311811207411 0.4560832425257963 1.0 0.7404218283097969 5 O15254 1 +Ubiquitin like protein ligase activity 0.3281037418783636 0.7384254214693264 0.4602559712782796 1.0 0.745001492799675 51 P19474,O95155,Q14527,O60858,P14373,Q13049,O75592,Q8IVV7 8 +Glutamate receptor binding 0.4506194199025523 0.7283882430365346 0.466375958196104 1.0 0.7511984764825296 10 P41440,O75955 2 +Thiolester hydrolase activity 0.4095233202732125 0.7278860288660685 0.466683356237985 1.0 0.7511984764825296 16 P50897 1 +Clathrin binding 0.3801495135436896 0.727183937892079 0.4671132843657026 1.0 0.7511984764825296 26 Q6ZVM7,Q9NUN5,O14976,Q5VW38 4 +Retinoic acid receptor binding 0.4818861978444715 0.7266907391244757 0.4674154278348674 1.0 0.7511984764825296 8 Q71SY5,Q13573 2 +Nadh dehydrogenase activity 0.3736615106312863 0.7201028683098987 0.4714616616263332 1.0 0.7535176200176279 28 P03886,O43676,O75380,O95831 4 +Symporter activity 0.4458038252809573 0.7049568886745213 0.4808370655303271 1.0 0.7646522547824338 10 O00400,P55011,P53985,Q9Y666,Q9Y6M7 5 +Nadp binding 0.3836970720192591 0.7035299287712271 0.4817255620528438 1.0 0.7646522547824338 20 Q9UBM7,Q13423,P00390 3 +Nad binding 0.3655542674982495 0.6835338280038559 0.4942695820809968 1.0 0.7742290819205077 29 P48735,P30837,Q00796 3 +Aspartic endopeptidase activity intramembrane cleaving 0.5878745889675234 0.6747870944352055 0.4998110408853939 1.0 0.780076309774751 3 Q8TCT8 1 +Nuclear receptor coactivator activity 0.3725747627382038 0.6594554621831339 0.509603337077732 1.0 0.7912473300831402 25 P12814,Q9P1Z2,Q9UPT9,Q9NPJ6 4 +Sodium ion transmembrane transporter activity 0.4801110241240571 0.6560416394799831 0.5117973329588605 1.0 0.7912619654737747 7 Q6P4Q7,P55011,Q9Y6M7 3 +Phospholipase binding 0.562463100298373 0.653504676356134 0.5134309756400535 1.0 0.7925086162496819 4 P07196 1 +Acetyltransferase activity 0.3503916788868033 0.6458490558058122 0.5183771148339877 1.0 0.7955450468355911 32 Q6N069,Q9BWD1 2 +Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor 0.4135120586795717 0.6457542541251494 0.5184385182762186 1.0 0.7955450468355911 14 Q9UBM7,Q15392,Q8N8N7 3 +Profilin binding 0.5791208791208805 0.6435986647014118 0.5198357163652056 1.0 0.7955450468355911 3 Q14247,Q8N8S7 2 +Transcription coregulator binding 0.3625649292913734 0.6414463748927781 0.5212327110038062 1.0 0.7955450468355911 28 Q9UQB8,O75530 2 +U4 snrna binding 0.5047822574493868 0.6394658729253712 0.522519907840395 1.0 0.7955450468355911 6 O43172,Q8WWY3,P55769 3 +Dynactin binding 0.4750018854441902 0.6348713627681933 0.5255123156408787 1.0 0.7955450468355911 7 Q8TD16,Q96RK4 2 +Oxidoreductase activity acting on single donors with incorporation of molecular oxygen 0.5761432423068401 0.6330840103531563 0.5266787833629889 1.0 0.7955450468355911 3 O00625 1 +C4 dicarboxylate transmembrane transporter activity 0.5287441018956578 0.6274866399139076 0.5303402910100288 1.0 0.7955450468355911 5 Q15758,Q9UBX3 2 +Proton transporting atp synthase activity rotational mechanism 0.4220507623563022 0.6251844335406002 0.5318500172958331 1.0 0.7955450468355911 12 P00846,O75964 2 +Proton channel activity 0.4220507623563022 0.6251844335406002 0.5318500172958331 1.0 0.7955450468355911 12 P00846,O75964 2 +Epidermal growth factor receptor binding 0.4723234225021975 0.6238383301151372 0.5327337642004624 1.0 0.7960325460880207 7 O95219,O00291 2 +Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.3713472812902577 0.6228681625727686 0.5333711612475245 1.0 0.7961513044981353 19 Q9UQ84 1 +Sumo transferase activity 0.5502688528695832 0.6097286662845669 0.542041561858847 1.0 0.8015474702306474 4 P14373 1 +Non membrane spanning protein tyrosine phosphatase activity 0.5097500686624461 0.6018619839548227 0.5472660114013204 1.0 0.8051016477007052 2 P24666 1 +Protein c terminus binding 0.3128501766059973 0.597424068830828 0.550224288216391 1.0 0.8057486344646871 57 P12956,Q9P1Z2,Q12834,Q9UQB8,P07196 5 +Tau protein kinase activity 0.4928686262901439 0.5933110854900789 0.5529729812967974 1.0 0.8075292037753791 6 O75116 1 +Plus end directed microtubule motor activity 0.4927150547347635 0.592722073322762 0.5533671666141304 1.0 0.8075292037753791 6 P52732,P33176 2 +Antiporter activity 0.4154880088498007 0.5926083636722848 0.553443280513189 1.0 0.8075292037753791 12 P41440,Q9UBX3,P51790 3 +Dynein complex binding 0.4906930419830053 0.5849816115727288 0.5585600811845439 1.0 0.8108496804174407 6 Q06787,Q9UQE7,P12270,Q8TD16 4 +Myosin binding 0.4092890402545751 0.5817203569225279 0.5607550572732838 1.0 0.8125075519381271 13 Q86VI3 1 +Polynucleotide adenylyltransferase activity 0.5045317220543712 0.5815929659206167 0.5608408820315733 1.0 0.8125075519381271 2 P51003 1 +Single stranded dna endodeoxyribonuclease activity 0.5418674464280018 0.5800766493936413 0.5618629296696442 1.0 0.8131032496471184 4 Q92878,P18887 2 +Histone deacetylase activity h3 k14 specific 0.5020598736610726 0.5720723475786397 0.5672729620269941 1.0 0.818069211506587 2 Q92769 1 +Voltage gated channel activity 0.4068032075883884 0.569188516515213 0.5692282129004278 1.0 0.8189363391578122 13 P21796 1 +Phosphate ion binding 0.5121211159582616 0.5664117707920799 0.5711138949150294 1.0 0.8191993887240546 5 Q8NCH0 1 +Peptidase activator activity 0.4086229922149443 0.558923790210755 0.5762137324381649 1.0 0.8221895675165005 12 Q9BXK5,P05067 2 +Ribosome binding 0.3216071496180478 0.5557322650129574 0.5783938962359105 1.0 0.8237206486313816 43 P46379 1 +Gamma tubulin binding 0.4552810009867231 0.55480120972164 0.5790306396127154 1.0 0.8238053068069241 7 Q96CW5 1 +Leukotriene c4 synthase activity 0.4965668772315204 0.5511083398423661 0.5815594087117351 1.0 0.8255955653826504 2 Q99735 1 +Gtpase activator activity 0.3103458769852467 0.5504297849201665 0.5820246242291145 1.0 0.8255955653826504 49 P46940,Q8TC07,Q86VI3,Q07960,A1A4S6,Q15437,Q15042,Q9Y4G8,Q4KMP7,Q96HS1,Q9HCU5,Q92888,P11274,Q14185,P49792 15 +Udp glucosyltransferase activity 0.5035878859412708 0.5357795362449165 0.592110926734922 1.0 0.8324554605425948 5 Q16739 1 +Tubulin binding 0.2973881680082252 0.5337137964286719 0.5935395624573037 1.0 0.8331537551466661 116 O15344,Q8NBT2,Q9Y496,Q8IWS0,Q9H6D7,O60313,Q9UH99,Q96CW5,Q08379,P12270,Q14203,Q96ED9,Q9NXR1,P29372,P33176,P23396,O15078,Q9UQ16,P52732,Q9Y448,O95239,P07197,Q15691,Q9UQE7,Q15555,P49354,Q86VS8,Q9UJC3,Q9BSJ2,O43663,Q96RK4 31 +Snap receptor activity 0.3722008347461826 0.5153010138001913 0.6063426906336224 1.0 0.8426838257851611 16 O15400,O43752,O60499,P51809 4 +Transforming growth factor beta binding 0.4864048338368482 0.5130654330870934 0.6079055503923931 1.0 0.8426838257851611 2 P06756 1 +Adp binding 0.3532879811341243 0.5126272514102254 0.6082120868105725 1.0 0.8426838257851611 20 P35579,P25705,P35580 3 +Protein membrane adaptor activity 0.4004277749886128 0.5043845772128924 0.6139911537806961 1.0 0.845719475333063 11 Q9NUN5,Q9UH99 2 +Sh3 domain binding 0.3501999641120647 0.4979178721069537 0.6185419298775514 1.0 0.8478956137706685 22 Q07666,Q96PU8,Q96JJ3,Q07960,Q9Y6W5,Q14185,P78536 7 +Cysteine type endopeptidase activity 0.3469237778144294 0.4907825042514842 0.6235802856649235 1.0 0.8516025434728864 25 Q96K76,P17655,Q86UV5,Q8NB14,Q93009,O15484,Q99538 7 +Translation activator activity 0.5318681318681333 0.4834237168066193 0.6287949116982845 1.0 0.8544203764973675 3 P11940,Q7Z478 2 +Vitamin binding 0.301178446387247 0.482727422946005 0.6292892892072413 1.0 0.8544203764973675 56 O94788,O75592,Q9NUN5,P41440 4 +Copper ion binding 0.4230276753800576 0.4777787628249129 0.6328076781672782 1.0 0.8560810404416361 8 O75592,P00403 2 +Neutral amino acid transmembrane transporter activity 0.4579115559308582 0.4638176374662749 0.6427784057712096 1.0 0.8640651136446145 6 Q15758,Q01650 2 +Lyase activity 0.2968259085562231 0.4597828757226648 0.6456720758727044 1.0 0.8643283792404776 63 P22830,O75592,P12956,O00584 4 +Long chain fatty acyl coa binding 0.471024443834105 0.4574840503605241 0.6473231638109311 1.0 0.8646847982577714 2 P22307 1 +Anaphase promoting complex binding 0.5224162853810602 0.4533657573022792 0.650285389586581 1.0 0.8672497672336926 3 Q12834 1 +Enzyme activator activity 0.2894993362219542 0.4501662202831086 0.6525905912712222 1.0 0.8691208760179383 119 P07602,O75569,Q86VI3,Q07960,Q15437,Q9Y4G8,O43169,Q9BXK5,Q12834,O75530,P41440,P11274,P10619,P05067,Q14185 15 +Sterol transporter activity 0.3873609204681743 0.4448081987716198 0.6564583688587804 1.0 0.8703451528766109 11 Q9H4L5,O15118,P61916 3 +Nucleoside triphosphatase regulator activity 0.2935374450810051 0.4314549767284482 0.6661375829318503 1.0 0.8721207260373897 85 Q92538,P55010,O94813,Q86VI3,Q15042,Q96N67,Q9HCU5,Q92888,O95714,Q8TC07,A1A4S6,Q07960,Q4KMP7,O75592,O00410,Q02818,Q9NZM3,Q9Y4G8,P11274,P80303,Q14185,P49792,P46940,Q15437,Q96HS1,A4D1U4,P49770 27 +Nucleoside diphosphatase activity 0.497371755242284 0.4314229151488668 0.6661608909465695 1.0 0.8721207260373897 4 Q86VD7 1 +Oxidoreductase activity acting on the ch ch group of donors 0.3265865325031695 0.4295409383423078 0.6675296080766764 1.0 0.8728703381816217 30 P50336,O15254,P49748,Q15392,Q9UBM7,Q7KZN9,Q8N8N7 7 +Modification dependent protein binding 0.2948358134275272 0.4252004098159406 0.6706905854658956 1.0 0.8736469689537798 58 P46379,Q7Z4V5 2 +Atpase coupled cation transmembrane transporter activity 0.3622876988548976 0.420319904889353 0.6742517707699218 1.0 0.8762816729405086 15 P16615 1 +Monosaccharide binding 0.3263997142097122 0.4114628940979468 0.6807331442275946 1.0 0.8806946480623549 29 O75503,P11717 2 +Protein deacetylase activity 0.4885957680681694 0.4040637915546828 0.6861658102224464 1.0 0.8845012757353382 4 O94776,Q92769,Q13547 3 +Syntaxin binding 0.3346710724173088 0.4023206768525036 0.6874480394205327 1.0 0.8845012757353382 21 O60499,Q08379,Q99747,O00186,O75150,Q5SQN1,P49755,P40222,O43752,Q9NUQ3,O15400 11 +Rna 7 methylguanosine cap binding 0.3914589465615232 0.4003515723107666 0.6888975878231374 1.0 0.8848396560068561 9 Q96F07 1 +Phosphatidylinositol transfer activity 0.4862743153999467 0.396949686984361 0.6914045628687273 1.0 0.8860168513178255 4 O14523 1 +Aspartic type peptidase activity 0.4861533937199088 0.3965805671011436 0.6916767851212737 1.0 0.8860168513178255 4 Q8TCT8 1 +Nucleobase containing compound kinase activity 0.3333708306619794 0.3943185693463302 0.6933458552665517 1.0 0.8865632038220154 20 Q5KU26,Q14168,P55263 3 +Microtubule motor activity 0.3412246056692918 0.3924171428217152 0.6947500216310454 1.0 0.8875633669359908 17 Q9UQE7,Q9Y496,Q02241,P52732,Q14807,O95239,P33176 7 +Ccr chemokine receptor binding 0.50034549738729 0.3862834458784751 0.6992867591699039 1.0 0.8913922378417304 3 P48681 1 +Mdm2 mdm4 family protein binding 0.4347214197297708 0.3839909367885864 0.7009851649301537 1.0 0.8913922378417304 6 P61927,P61289,Q96JB5 3 +Atp dependent chromatin remodeler activity 0.4817375148159805 0.383200347181301 0.7015712206219724 1.0 0.8913922378417304 4 Q9H4L7,P28370 2 +Guanylyltransferase activity 0.4474045591870264 0.3774467072518161 0.705841661878178 1.0 0.8937320776398935 2 Q9Y5P6 1 +Rrna cytosine methyltransferase activity 0.495702418305315 0.3727691612318537 0.7093202569612747 1.0 0.894960218111175 3 Q96P11 1 +Calcium dependent cysteine type endopeptidase activity 0.4719811277602835 0.3543455790645339 0.7230799135740988 1.0 0.9037637659538148 4 O15484 1 +Nad dependent protein deacetylase activity 0.4884615384615401 0.3521370157736499 0.7247355094201806 1.0 0.9037637659538148 3 Q92769,Q13547 2 +Passive transmembrane transporter activity 0.2948813971973684 0.3374369230162896 0.7357875545508248 1.0 0.9114117848965804 43 P21796,P00846,P45880,P25705,Q9H813,P39210,O75964 7 +Protein transporter activity 0.3222005440333389 0.3341849844684692 0.7382399739639898 1.0 0.9114117848965804 18 O96008,Q07820,Q99595,P49755,Q9HD20,Q9UGP8 6 +Lipid transporter activity 0.3163370738218287 0.333111075627326 0.7390504392372985 1.0 0.9114117848965804 28 P11166,Q9H4L5,O15118,P61916,Q9H1P3,O14678,O14523 7 +G quadruplex dna binding 0.4172741077372773 0.3278442813944811 0.7430294042654078 1.0 0.9134433637595968 6 Q9H2U1 1 +Carbohydrate binding 0.2842139830191795 0.3204278629786948 0.748644006506491 1.0 0.9138708274463324 49 Q00796,P11717,O00754,Q5KU26,P08236,P10253,O75503,O75592,P13807 9 +U3 snorna binding 0.3569304960062017 0.3093710228571242 0.7570393103308481 1.0 0.9193354824660708 10 Q14692,Q8IY37,Q68CQ4,P55769 4 +Endonuclease activity 0.2911719245974958 0.308802857969907 0.7574714949853152 1.0 0.9193354824660708 43 Q9UQ84,Q8N2A8 2 +Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters 0.310720828997425 0.2987319029042878 0.7651446129378843 1.0 0.9239399086788428 28 Q9UQ84,Q8IV08 2 +Minus end directed microtubule motor activity 0.421038176325174 0.2969055234578137 0.7665386391146554 1.0 0.9239399086788428 2 Q8NCM8 1 +Nucleoside binding 0.446465102598341 0.2838495175196279 0.776525705002685 1.0 0.931961464288336 4 O43707 1 +Ubiquitin conjugating enzyme binding 0.3486716947088809 0.2821260332601205 0.7778468720424907 1.0 0.9319794176361328 11 Q92564,Q9UBW7 2 +Gtpase binding 0.2807765810904031 0.2795635113807787 0.7798124049041344 1.0 0.932768065212238 103 Q9Y496,Q86VI3,Q8TD16,Q96N67,Q92696,Q9Y5S2,Q07960,Q8IUD2,O75116,Q9BZG1,O75592,Q5VSL9,Q14457,O00410,Q8IWJ2,Q13464,Q96F07,Q7L576,Q9NRA0,Q9NUQ9,Q96CN9,Q86YV9,Q01082,Q8TBA6 24 +Oxidoreductase activity acting on nad p h 0.2922996665701657 0.2784512399732682 0.7806659902722957 1.0 0.9330070084745108 36 P03886,O43676,O75251,O95831,O75380,Q7KZN9 6 +Ubiquitin protein transferase inhibitor activity 0.3675378266850199 0.2752909956646294 0.7830926817374699 1.0 0.9351240643007276 8 P62841,P61927,Q92990,P46777,P62081,P60866,P62913 7 +3 5 dna helicase activity 0.3446187723644374 0.2628507786297459 0.7926655955090816 1.0 0.9381964077884488 10 P46063,Q8N3C0,P33993,Q08211,P33992,P49736,Q14566,P19447,P54132 9 +Lamin binding 0.353889805570763 0.2608443830136066 0.7942125161937255 1.0 0.9381964077884488 9 Q9UH99,Q14739 2 +Protein dimerization activity 0.3008109116000156 0.2552650035916682 0.7985184278392181 1.0 0.9401697991143269 257 P22830,Q14108,O15344,Q9HD42,P14373,O75027,O00291,Q8TCT8,P06280,P16278,P35579,Q9UKU0,P19474,Q8WVQ1,Q06481,Q9BY67,P02786,O95831,Q15070,P42892,P67936,Q9BPX6,Q8TCG1,P29372,P20585,P12814,Q8N2A8,P07602,Q8IY95,Q01664,O43707,P31350,Q9Y448,P09493,Q9BX67,Q15075,O75569,Q13555,Q9Y5X1,O95684,Q8TBA6,Q9NWW5,Q9NQH7,Q9UPN4,Q8IYU8,P23246,Q9GZY8 47 +G protein coupled receptor binding 0.2851803244630965 0.2329249267390018 0.8158197019934113 1.0 0.9511231329612728 37 P22466 1 +Histone kinase activity 0.34013138657967 0.215580153709394 0.8293150270928333 1.0 0.9573305425197762 9 O14965,P06493,Q9UIG0 3 +Transcription regulator inhibitor activity 0.4182467710909729 0.215157539119118 0.8296444944890788 1.0 0.9573305425197762 4 Q9UER7,Q96ST3,Q9NX58 3 +Thioredoxin disulfide reductase activity 0.3886294973908236 0.2125517074008561 0.8316766425248439 1.0 0.9586450475629662 2 Q6DKJ4 1 +Spectrin binding 0.35388496283253 0.2071552697370097 0.8358885991153027 1.0 0.961170854905348 7 O43491,P35611,Q9Y496 3 +Microtubule plus end binding 0.3281034214819937 0.2061557685566285 0.8366692372375182 1.0 0.9612938820756348 11 Q9Y448,Q15555 2 +Ubiquitin protein transferase regulator activity 0.3257037685036935 0.2005710680287818 0.8410339826895266 1.0 0.963487147666846 12 P61927,Q12834,Q92990 3 +Ubiquitin like protein conjugating enzyme binding 0.3121664238057035 0.1903580815425855 0.8490285431083553 1.0 0.9692509848124984 15 Q92564,Q9Y4X5,Q9UBW7 3 +Lysophospholipid acyltransferase activity 0.3643475941398292 0.182590943329591 0.855118991054344 1.0 0.9725120909681992 6 Q96N66 1 +Acetyl coa hydrolase activity 0.415934065934068 0.1794813604189753 0.8575597519138811 1.0 0.973876952355854 3 Q9Y305,O14734 2 +Transmembrane transporter binding 0.2862645310315266 0.177739833094028 0.858927301005594 1.0 0.973876952355854 30 P21796,P12814,P16615 3 +Hydrolase activity acting on carbon nitrogen but not peptide bonds 0.2918448349494199 0.1764946290067147 0.8599053678825341 1.0 0.973876952355854 26 P00813 1 +Fatty acid synthase activity 0.3707772589947781 0.1735994149706064 0.8621802918254529 1.0 0.974905924274898 2 Q8IVS2 1 +Heat shock protein binding 0.2638123498118099 0.1599921834697469 0.8728872315889125 1.0 0.981237770171174 53 P23396,P02786,Q8IXB1,P46379 4 +Glucosyltransferase activity 0.3181680646337594 0.1508514507909931 0.8800928987599448 1.0 0.9848696427386656 9 Q16739,P13807 2 +Four way junction dna binding 0.322145804676761 0.145314944286341 0.8844622161291453 1.0 0.9862893293812426 8 P43246,P52701,P25490,Q14191,P09429,P26583,P54132 7 +Phosphatidylinositol 3 4 5 trisphosphate binding 0.3090793675712009 0.143780654207878 0.885673679834807 1.0 0.9862893293812426 11 P46940,Q92538,Q96AC1,P31749 4 +Nucleotidase activity 0.3270269404145436 0.1406599208636701 0.8881386087393341 1.0 0.9862893293812426 7 Q9NX62 1 +Histone methyltransferase binding 0.343414902392098 0.1370467914703462 0.8909938097621586 1.0 0.9862893293812426 6 O00567,P08238,O95785,Q13185,P35222 5 +Abc type glutathione s conjugate transporter activity 0.3391925295248512 0.1181829359739796 0.9059227103161552 1.0 0.9928968568518846 2 O15439 1 +Atpase coupled lipid transmembrane transporter activity 0.3391925295248512 0.1181829359739796 0.9059227103161552 1.0 0.9928968568518846 2 O15439 1 +Tripeptide transmembrane transporter activity 0.3391925295248512 0.1181829359739796 0.9059227103161552 1.0 0.9928968568518846 2 O15439 1 +Glutathione transmembrane transporter activity 0.3391925295248512 0.1181829359739796 0.9059227103161552 1.0 0.9928968568518846 2 O15439 1 +Oligopeptide transmembrane transporter activity 0.3391925295248512 0.1181829359739796 0.9059227103161552 1.0 0.9928968568518846 2 O15439 1 +Nucleoside monophosphate kinase activity 0.2990544184930377 0.1168366518184518 0.9069894986921032 1.0 0.9929047105113448 10 Q14168 1 +Single stranded dna helicase activity 0.2965313325372282 0.1056169408281689 0.9158862830948122 1.0 0.9986209620699152 12 P40938 1 +Ubiquitin ubiquitin ligase activity 0.3033554663025294 0.1029261739561577 0.9180215642051874 1.0 1.0 8 O95155 1 +Tau protein binding 0.2750058700705744 0.100289751954719 0.9201142932286668 1.0 1.0 20 O75116,Q13464,Q14203 3 +Histone acetyltransferase binding 0.3041804180418101 0.0944507135913953 0.924751132203146 1.0 1.0 7 Q9H6U6,O95905,Q15650,P42224,P26367,P04637 6 +Oxidoreduction driven active transmembrane transporter activity 0.262162806181276 0.0910630265502211 0.9274425110764806 1.0 1.0 38 P03886,O43676,O75306,O75251,O75380,Q7KZN9,P00403 7 +Zinc ion transmembrane transporter activity 0.3546492108205418 0.0875837783867113 0.9302074955991212 1.0 1.0 3 Q8N1S5 1 +Peptide transmembrane transporter activity 0.3424555410627101 0.084736426026382 0.932470936315832 1.0 1.0 4 O15439 1 +Rna cap binding 0.2894444461541016 0.0845360286915074 0.9326302585960332 1.0 1.0 13 Q7L576,Q96F07,Q13325 3 +Efflux transmembrane transporter activity 0.3393789502610802 0.0811262618650098 0.935341540571076 1.0 1.0 4 O15439,P08183,Q9NP58 3 +Protein kinase a catalytic subunit binding 0.2959295929593042 0.0801425557671204 0.9361238769692872 1.0 1.0 7 P10644,P49841,P13861,P15311,O43164,P41240 6 +Frizzled binding 0.3467032967032987 0.0792687995461848 0.9368188225431824 1.0 1.0 3 Q15334,O14641 2 +Dna apurinic or apyrimidinic site endonuclease activity 0.3364310209696255 0.0777840928194033 0.9379998001986982 1.0 1.0 4 P23396 1 +Active ion transmembrane transporter activity 0.2533562367555544 0.0767261438860748 0.9388414060280076 1.0 1.0 48 P20674,O00400,P55011,P16615,P51790,Q9HD20,P51798,P41440,Q7KZN9,Q9Y666,Q9Y6M7,P00403 12 +Bubble dna binding 0.3439560439560458 0.0765727710496048 0.9389634208920228 1.0 1.0 3 P09429,P54132 2 +Dna binding bending 0.321880153930739 0.0764007647567338 0.9391002611979689 1.0 1.0 5 P11388,P09429,P26583,Q00059 4 +Macromolecule transmembrane transporter activity 0.2804249349642307 0.0757015586205686 0.939656535954041 1.0 1.0 15 P51991,O96008,Q07820,Q99595,P49755 5 +Abc type xenobiotic transporter activity 0.3392857142857161 0.0721953279867949 0.9424464631998342 1.0 1.0 3 O15439,P08183 2 +Snare binding 0.2585558338667581 0.0714135801156567 0.9430686018358234 1.0 1.0 34 A2RRP1,O60499,P51809,Q08379,Q99747,Q86Y82,P49755,O43752,O15400 9 +17 beta hydroxysteroid dehydrogenase nadpplus activity 0.3365384615384637 0.0697393097871493 0.9444011532478396 1.0 1.0 3 Q53GQ0,P56937 2 +Tumor necrosis factor receptor binding 0.3299450549450568 0.0641950475594791 0.9488149207381388 1.0 1.0 3 Q12931,P42224 2 +Type i transforming growth factor beta receptor binding 0.3164835164835184 0.0543388268411366 0.9566652158880152 1.0 1.0 3 Q96AC1,Q9UNH7 2 +Tpr domain binding 0.3097004671613173 0.052462381133834 0.9581602695418115 1.0 1.0 4 O76094,P07900,P08238 3 +Sulfur compound binding 0.2505589548227896 0.0522161110626063 0.9583564956741776 1.0 1.0 47 P05067,Q06481 2 +Syntaxin 1 binding 0.3003572410002881 0.0455832445012917 0.9636424242403858 1.0 1.0 4 P46459,O00186,O75150 3 +L serine transmembrane transporter activity 0.2983152082701644 0.0438716993932343 0.965006674185252 1.0 1.0 3 Q15758 1 +Dna topoisomerase activity 0.296978021978024 0.0432183565318169 0.9655274723630962 1.0 1.0 3 P11388,P11387 2 +5s rrna binding 0.2782513060214588 0.041253631174122 0.9670936985382071 1.0 1.0 6 Q9H7B2,P39023,P46777,Q9NZM5,P62913 5 +Atp dependent activity acting on dna 0.2492309412769279 0.0403490626263259 0.9678148392827316 1.0 1.0 58 Q9UQE7,Q9UNY4,P28370,Q14527,Q92878,P40937,Q9H2U1,P40938,P12956,Q2NKX8,Q96RR1,P41440,Q14839,Q14566 14 +Phosphoric ester hydrolase activity 0.2486930233941088 0.03976215999702 0.96828274430646 1.0 1.0 72 Q8N2A8,Q8IV08,Q9NX62,Q13555,Q9NPH0,P10586 6 +Identical protein binding 0.3007098055906589 0.0376568035242622 0.9699613173430108 1.0 1.0 544 P22830,P14174,O75027,Q9UM22,Q9UQB8,P05067,P19474,Q06481,P53985,P35790,P42892,O43865,Q8N2A8,P07602,P43490,Q9H773,O75530,Q4G0X4,Q9BRK5,Q9NQE9,P08670,Q13555,Q9Y5X1,Q15165,Q16740,Q9NQX7,P07196,Q9GZY8,P98175,Q8N3R9,Q8TCT8,P06280,Q00796,P16278,P11717,O95563,Q9UHX1,Q9UH99,Q96ED9,P67936,O43805,O75592,P32929,Q13049,Q14457,O15078,P55735,Q96RU3,Q03252,P09493,Q9NWW5,Q14108,O15344,Q9HD42,P35579,P11166,Q9BY67,Q9BPX6,Q96RR1,P33176,P20585,P12814,Q01664,O43707,Q9Y448,Q9H9S5,Q15555,Q15075,O75569,Q9NWH9,O95684,Q8TBA6,Q9NQH7,Q9UPN4,Q8NFF5,Q14566,P23246,P14373,O00291,Q9NY93,Q9Y5X2,Q9UKU0,Q8WVQ1,P49748,Q08379,P02786,P80404,Q15070,Q8TCG1,P29372,Q8IY95,Q8IWJ2,Q7LG56 93 +Tumor necrosis factor receptor superfamily binding 0.2717779609783053 0.0299520711375582 0.9761052776937068 1.0 1.0 4 Q12931,Q9NXR7,P42224 3 +Organic acid binding 0.2534364267454156 0.0281840814282007 0.9775153333616112 1.0 1.0 32 P11717,P41440 2 +Ribosomal small subunit binding 0.2631991940118703 0.0231491061900912 0.9815313350907352 1.0 1.0 12 P46199,Q15056 2 +Protein arginine n methyltransferase activity 0.2559098405717482 0.0221231825011462 0.9823496940384376 1.0 1.0 5 O60678,Q7L592,O14744,Q86X55 4 +Ubiquitin like protein specific protease activity 0.2478282289579284 0.01669056862238 0.9866834712635644 1.0 1.0 35 Q96RU2,Q96K76,Q86UV5,Q8NB14,Q93009,Q9BT78,Q9NUQ7,Q9UPT9 8 +Mrna 3 utr au rich region binding 0.2597458706933209 0.0162496376308944 0.9870352355774156 1.0 1.0 12 Q9H2U1,Q92945,Q13151 3 +Transcription coactivator activity 0.2544858970563048 0.0107568881280438 0.9914174105568254 1.0 1.0 94 P12814,P19474,Q96TA1,Q9NPJ6,O60858,Q13049,Q9P1Z2,Q13573,Q9UPT9 9 diff --git a/msigdb_gomf/selections.json b/msigdb_gomf/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f2f8f3241e23ed5dca26d2091c8561dfad6a75d6 --- /dev/null +++ b/msigdb_gomf/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1 4 alpha oligoglucan phosphorylase activity", "1 acylglycerophosphocholine o acyltransferase activity", "1 alkyl 2 acetylglycerophosphocholine esterase activity", "1 phosphatidylinositol 3 kinase activity", "1 phosphatidylinositol 4 kinase activity", "1 phosphatidylinositol 4 phosphate 3 kinase activity", "1 phosphatidylinositol 4 phosphate 5 kinase activity", "1 phosphatidylinositol binding", "14 3 3 protein binding", "17 beta hydroxysteroid dehydrogenase nadplus activity", "17 beta hydroxysteroid dehydrogenase nadpplus activity", "2 acylglycerol 3 phosphate o acyltransferase activity", "2 acylglycerol o acyltransferase activity", "2 iron 2 sulfur cluster binding", "2 oxoglutarate dependent dioxygenase activity", "3 5 dna helicase activity", "3 5 exodeoxyribonuclease activity", "3 5 exonuclease activity", "3 beta hydroxy delta5 steroid dehydrogenase activity", "3 hydroxyacyl coa dehydratase activity", "3 hydroxyacyl coa dehydrogenase activity", "3 phosphoadenosine 5 phosphosulfate binding", "4 iron 4 sulfur cluster binding", "5 3 dna helicase activity", "5 3 exodeoxyribonuclease activity", "5 3 exonuclease activity", "5 deoxyribose 5 phosphate lyase activity", "5alpha androstane 3beta 17beta diol dehydrogenase activity", "5s rrna binding", "7s rna binding", "7sk snrna binding", "Abc type glutathione s conjugate transporter activity", "Abc type transporter activity", "Abc type xenobiotic transporter activity", "Acetyl coa c acetyltransferase activity", "Acetyl coa c acyltransferase activity", "Acetyl coa hydrolase activity", "Acetylcholine receptor binding", "Acetylgalactosaminyltransferase activity", "Acetylglucosaminyltransferase activity", "Acetyltransferase activity", "Acid amino acid ligase activity", "Acid phosphatase activity", "Acid thiol ligase activity", "Acidic amino acid transmembrane transporter activity", "Actin binding", "Actin filament binding", "Actin monomer binding", "Actinin binding", "Active ion transmembrane transporter activity", "Active transmembrane transporter activity", "Activin binding", "Acyl carnitine transmembrane transporter activity", "Acyl coa binding", "Acyl coa dehydrogenase activity", "Acyl coa oxidase activity", "Acylglycerol lipase activity", "Acylglycerol o acyltransferase activity", "Acyltransferase activity", "Acyltransferase acyl groups converted into alkyl on transfer", "Adenosine deaminase activity", "Adenyl nucleotide binding", "Adenyl nucleotide exchange factor activity", "Adenylate cyclase binding", "Adenylate kinase activity", "Adenylyltransferase activity", "Adp binding", "Adp ribose diphosphatase activity", "Adp transmembrane transporter activity", "Adrenergic receptor binding", "Alanine transmembrane transporter activity", "Alcohol binding", "Alcohol dehydrogenase activity zinc dependent", "Alcohol dehydrogenase nad p plus activity", "Alcohol dehydrogenase nadpplus activity", "Aldehyde dehydrogenase nad p plus activity", "Aldehyde lyase activity", "Alditol nadpplus 1 oxidoreductase activity", "Aldo keto reductase nadp activity", "Alkali metal ion binding", "Alpha actinin binding", "Alpha catenin binding", "Alpha glucosidase activity", "Alpha tubulin binding", "Amide binding", "Amide transmembrane transporter activity", "Amidine lyase activity", "Amino acid binding", "Amino acid cation symporter activity", "Amino acid sodium symporter activity", "Amino acid transmembrane transporter activity", "Aminoacyl trna editing activity", "Aminoacylase activity", "Aminopeptidase activity", "Aminophospholipid flippase activity", "Ammonium transmembrane transporter activity", "Amp activated protein kinase activity", "Amp binding", "Amyloid beta binding", "Anaphase promoting complex binding", "Androgen receptor binding", "Androstan 3 alpha 17 beta diol dehydrogenase activity", "Angiotensin receptor binding", "Anion cation symporter activity", "Anion channel activity", "Anion sodium symporter activity", "Anion transmembrane transporter activity", "Ankyrin binding", "Ankyrin repeat binding", "Annealing activity", "Antigen binding", "Antioxidant activity", "Antiporter activity", "Ap 2 adaptor complex binding", "Apolipoprotein a i binding", "Apolipoprotein binding", "Apolipoprotein receptor binding", "Arachidonate coa ligase activity", "Arginine binding", "Armadillo repeat domain binding", "Aromatic amino acid transmembrane transporter activity", "Arp2 3 complex binding", "Arrestin family protein binding", "Aryl hydrocarbon receptor binding", "Arylesterase activity", "Arylsulfatase activity", "Aspartic endopeptidase activity intramembrane cleaving", "Aspartic type endopeptidase inhibitor activity", "Aspartic type peptidase activity", "Atp dependent activity", "Atp dependent activity acting on dna", "Atp dependent activity acting on rna", "Atp dependent chromatin remodeler activity", "Atp dependent dna dna annealing activity", "Atp dependent peptidase activity", "Atp dependent protein binding", "Atp gated ion channel activity", "Atp hydrolysis activity", "Atp transmembrane transporter activity", "Atpase activator activity", "Atpase binding", "Atpase coupled cation transmembrane transporter activity", "Atpase coupled inorganic anion transmembrane transporter activity", "Atpase coupled intramembrane lipid transporter activity", "Atpase coupled ion transmembrane transporter activity", "Atpase coupled lipid transmembrane transporter activity", "Atpase coupled transmembrane transporter activity", "Atpase inhibitor activity", "Atpase regulator activity", "Axon guidance receptor activity", "Azole transmembrane transporter activity", "Basal transcription machinery binding", "Basic amino acid transmembrane transporter activity", "Benzodiazepine receptor activity", "Beta 1 3 galactosyltransferase activity", "Beta 2 adrenergic receptor binding", "Beta 2 microglobulin binding", "Beta catenin binding", "Beta galactosidase activity", "Beta n acetylhexosaminidase activity", "Beta tubulin binding", "Bh domain binding", "Bh3 domain binding", "Bhlh transcription factor binding", "Bicarbonate transmembrane transporter activity", "Bile acid binding", "Bile acid transmembrane transporter activity", "Bioactive lipid receptor activity", "Biotin binding", "Box h aca snorna binding", "Branched chain amino acid transmembrane transporter activity", "Bubble dna binding", "C acetyltransferase activity", "C acyltransferase activity", "C methyltransferase activity", "C palmitoyltransferase activity", "C x c chemokine binding", "C x3 c chemokine binding", "C2h2 zinc finger domain binding", "C3hc4 type ring finger domain binding", "C4 dicarboxylate transmembrane transporter activity", "Cadherin binding", "Cadherin binding involved in cell cell adhesion", "Calcium activated cation channel activity", "Calcium cation antiporter activity", "Calcium channel inhibitor activity", "Calcium channel regulator activity", "Calcium dependent cysteine type endopeptidase activity", "Calcium dependent phospholipid binding", "Calcium dependent protein binding", "Calcium dependent protein kinase activity", "Calcium dependent protein serine threonine phosphatase activity", "Calcium independent phospholipase a2 activity", "Calcium ion binding", "Calcium ion transmembrane transporter activity", "Calmodulin binding", "Calmodulin dependent protein kinase activity", "Calmodulin dependent protein phosphatase activity", "Camp binding", "Camp dependent protein kinase activity", "Camp dependent protein kinase inhibitor activity", "Camp dependent protein kinase regulator activity", "Camp response element binding", "Carbohydrate binding", "Carbohydrate derivative transmembrane transporter activity", "Carbohydrate kinase activity", "Carbohydrate phosphatase activity", "Carbohydrate transmembrane transporter activity", "Carbon carbon lyase activity", "Carbon nitrogen ligase activity with glutamine as amido n donor", "Carbon nitrogen lyase activity", "Carbon oxygen lyase activity", "Carbon sulfur lyase activity", "Carbonyl reductase nadph activity", "Carboxy lyase activity", "Carboxylic acid binding", "Carboxylic ester hydrolase activity", "Carboxypeptidase activity", "Card domain binding", "Cardiolipin binding", "Cargo adaptor activity", "Cargo receptor activity", "Carnitine o acyltransferase activity", "Catalytic activity acting on a glycoprotein", "Catalytic activity acting on a nucleic acid", "Catalytic activity acting on a rrna", "Catalytic activity acting on a trna", "Catalytic activity acting on dna", "Catalytic activity acting on rna", "Cation cation antiporter activity", "Cation channel activity", "Cation chloride symporter activity", "Cation transmembrane transporter activity", "Ccr chemokine receptor binding", "Ccr3 chemokine receptor binding", "Ccr5 chemokine receptor binding", "Cdp alcohol phosphatidyltransferase activity", "Cell adhesion mediator activity", "Cell adhesion molecule binding", "Cell adhesive protein binding involved in bundle of his cell purkinje myocyte communication", "Cell cell adhesion mediator activity", "Cell matrix adhesion mediator activity", "Centromeric dna binding", "Ceramide 1 phosphate binding", "Ceramide 1 phosphate transfer activity", "Ceramide binding", "Cgmp binding", "Channel activator activity", "Channel inhibitor activity", "Channel regulator activity", "Chaperone binding", "Chemoattractant activity", "Chemokine binding", "Chemokine receptor binding", "Chemorepellent activity", "Chitin binding", "Chloride channel inhibitor activity", "Chloride channel regulator activity", "Chloride ion binding", "Chloride transmembrane transporter activity", "Cholesterol binding", "Chondroitin sulfate binding", "Chromatin binding", "Chromatin dna binding", "Chromo shadow domain binding", "Cis regulatory region sequence specific dna binding", "Cis trans isomerase activity", "Class i dna apurinic or apyrimidinic site endonuclease activity", "Clathrin binding", "Clathrin heavy chain binding", "Clathrin light chain binding", "Co smad binding", "Coa hydrolase activity", "Coa transferase activity", "Cobalamin binding", "Collagen binding", "Collagen binding involved in cell matrix adhesion", "Collagen receptor activity", "Complement binding", "Complement component c1q complex binding", "Complement component c3b binding", "Connexin binding", "Copper chaperone activity", "Copper ion binding", "Core promoter sequence specific dna binding", "Coreceptor activity", "Coreceptor activity involved in wnt signaling pathway", "Coreceptor activity involved in wnt signaling pathway planar cell polarity pathway", "Corticotropin releasing hormone receptor binding", "Crossover junction endodeoxyribonuclease activity", "Cullin family protein binding", "Cuprous ion binding", "Cxcr chemokine receptor binding", "Cyclase activity", "Cyclase regulator activity", "Cyclic nucleotide binding", "Cyclic nucleotide dependent protein kinase activity", "Cyclic nucleotide phosphodiesterase activity", "Cyclin binding", "Cyclin dependent protein kinase activity", "Cyclin dependent protein serine threonine kinase inhibitor activity", "Cyclin dependent protein serine threonine kinase regulator activity", "Cyclohydrolase activity", "Cyclosporin a binding", "Cysteine type endopeptidase activity", "Cysteine type endopeptidase inhibitor activity", "Cysteine type endopeptidase inhibitor activity involved in apoptotic process", "Cysteine type endopeptidase regulator activity involved in apoptotic process", "Cysteine type exopeptidase activity", "Cysteine type peptidase activity", "Cytidine deaminase activity", "Cytidylyltransferase activity", "Cytochrome b5 reductase activity acting on nad p h", "Cytokine activity", "Cytokine binding", "Cytokine receptor binding", "Cytoskeletal anchor activity", "Cytoskeletal motor activity", "Cytoskeletal protein binding", "Cytoskeleton nuclear membrane anchor activity", "D glucose transmembrane transporter activity", "D loop dna binding", "D threo aldose 1 dehydrogenase activity", "D1 dopamine receptor binding", "Damaged dna binding", "Deacetylase activity", "Dead h box rna helicase binding", "Deaminase activity", "Death domain binding", "Death receptor activity", "Death receptor binding", "Dehydroascorbic acid transmembrane transporter activity", "Demethylase activity", "Deoxycytidine deaminase activity", "Deoxynucleoside kinase activity", "Deoxyribonuclease activity", "Deoxyribonuclease i activity", "Diacylglycerol binding", "Diacylglycerol kinase activity", "Dicarboxylic acid transmembrane transporter activity", "Dihydropyrimidinase activity", "Dioxygenase activity", "Dipeptidase activity", "Dipeptidyl peptidase activity", "Diphosphotransferase activity", "Disordered domain specific binding", "Disulfide oxidoreductase activity", "Dna apurinic or apyrimidinic site endonuclease activity", "Dna binding bending", "Dna binding transcription activator activity", "Dna binding transcription factor activity", "Dna binding transcription factor binding", "Dna binding transcription repressor activity", "Dna clamp loader activity", "Dna directed dna polymerase activity", "Dna dna annealing activity", "Dna helicase activity", "Dna insertion or deletion binding", "Dna methyltransferase activity", "Dna n glycosylase activity", "Dna polymerase activity", "Dna polymerase binding", "Dna replication origin binding", "Dna secondary structure binding", "Dna topoisomerase activity", "Dna translocase activity", "Dolichyl diphosphooligosaccharide protein glycotransferase activity", "Dolichyl phosphate mannose protein mannosyltransferase activity", "Dopamine receptor binding", "Double stranded methylated dna binding", "Double stranded rna adenosine deaminase activity", "Double stranded rna binding", "Double stranded telomeric dna binding", "Dttp diphosphatase activity", "Dynactin binding", "Dynein complex binding", "Dynein heavy chain binding", "Dynein intermediate chain binding", "Dynein light chain binding", "Dynein light intermediate chain binding", "Dystroglycan binding", "E box binding", "Efflux transmembrane transporter activity", "Electron transfer activity", "Endodeoxyribonuclease activity", "Endodeoxyribonuclease activity producing 3 phosphomonoesters", "Endodeoxyribonuclease activity producing 5 phosphomonoesters", "Endonuclease activity", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 3 phosphomonoesters", "Endonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Endopeptidase activator activity", "Endopeptidase activity", "Endopeptidase regulator activity", "Endopolyphosphatase activity", "Endoribonuclease activity", "Endoribonuclease activity producing 3 phosphomonoesters", "Endoribonuclease activity producing 5 phosphomonoesters", "Enoyl coa hydratase activity", "Enzyme activator activity", "Enzyme inhibitor activity", "Enzyme regulator activity", "Ephrin receptor activity", "Ephrin receptor binding", "Epidermal growth factor receptor binding", "Epoxide hydrolase activity", "Er retention sequence binding", "Erbb 3 class receptor binding", "Estradiol 17 beta dehydrogenase activity", "Estrogen receptor binding", "Ether hydrolase activity", "Eukaryotic initiation factor 4e binding", "Exodeoxyribonuclease activity", "Exogenous protein binding", "Exonuclease activity", "Exonuclease activity active with either ribo or deoxyribonucleic acids and producing 5 phosphomonoesters", "Exopeptidase activity", "Exoribonuclease activity", "Exoribonuclease activity producing 5 phosphomonoesters", "Extracellular matrix binding", "Extracellular matrix constituent conferring elasticity", "Extracellular matrix protein binding", "Extracellular matrix structural constituent", "Fad binding", "Fatty acid binding", "Fatty acid derivative binding", "Fatty acid ligase activity", "Fatty acid synthase activity", "Fatty acid transmembrane transporter activity", "Ferric iron binding", "Ferrous iron binding", "Fibroblast growth factor binding", "Fibroblast growth factor receptor binding", "Fibronectin binding", "Filamin binding", "Fk506 binding", "Flap endonuclease activity", "Flavin adenine dinucleotide binding", "Flippase activity", "Floppase activity", "Fmn binding", "Folic acid binding", "Folic acid transmembrane transporter activity", "Four way junction dna binding", "Four way junction helicase activity", "Frizzled binding", "Fructose 2 6 bisphosphate 2 phosphatase activity", "Fructose 6 phosphate binding", "Fructose binding", "Fucosyltransferase activity", "G protein activity", "G protein alpha subunit binding", "G protein beta gamma subunit complex binding", "G protein beta subunit binding", "G protein coupled glutamate receptor binding", "G protein coupled opioid receptor activity", "G protein coupled receptor activity", "G protein coupled receptor binding", "G protein coupled serotonin receptor binding", "G quadruplex dna binding", "G quadruplex rna binding", "G rich strand telomeric dna binding", "Gaba receptor binding", "Galactosidase activity", "Galactoside binding", "Galactosyltransferase activity", "Gamma aminobutyric acid transmembrane transporter activity", "Gamma catenin binding", "Gamma tubulin binding", "Ganglioside binding", "Gap junction channel activity", "Gap junction hemi channel activity", "Gated channel activity", "Gdp binding", "Gdp dissociation inhibitor activity", "General transcription initiation factor activity", "General transcription initiation factor binding", "Glucocorticoid receptor binding", "Glucose binding", "Glucosidase activity", "Glucosyltransferase activity", "Glucuronosyl n acetylgalactosaminyl proteoglycan 4 beta n acetylgalactosaminyltransferase activity", "Glucuronosyltransferase activity", "Glutamate binding", "Glutamate receptor binding", "Glutathione disulfide oxidoreductase activity", "Glutathione oxidoreductase activity", "Glutathione peroxidase activity", "Glutathione transferase activity", "Glutathione transmembrane transporter activity", "Glyceraldehyde 3 phosphate dehydrogenase nadplus non phosphorylating activity", "Glycerophosphodiester phosphodiesterase activity", "Glycerophospholipid flippase activity", "Glycine binding", "Glycolipid binding", "Glycolipid mannosyltransferase activity", "Glycosaminoglycan binding", "Glycosphingolipid binding", "Glycosyltransferase activity", "Gpi anchor binding", "Gpi linked ephrin receptor activity", "Growth factor activity", "Growth factor binding", "Growth factor receptor binding", "Gtp dependent protein binding", "Gtpase activating protein binding", "Gtpase activator activity", "Gtpase activity", "Gtpase binding", "Gtpase inhibitor activity", "Guanosine diphosphatase activity", "Guanyl nucleotide binding", "Guanyl nucleotide exchange factor activity", "Guanylate kinase activity", "Guanylyltransferase activity", "H4 histone acetyltransferase activity", "Heat shock protein binding", "Helicase activity", "Heme transmembrane transporter activity", "Heparan sulfate proteoglycan binding", "Heparan sulfate sulfotransferase activity", "Heparin binding", "Hexokinase activity", "Hexosaminidase activity", "Hexosyltransferase activity", "High density lipoprotein particle binding", "Histone acetyltransferase binding", "Histone arginine n methyltransferase activity", "Histone binding", "Histone deacetylase activity h3 k14 specific", "Histone deacetylase binding", "Histone deacetylase regulator activity", "Histone h3 di monomethyl lysine 9 demethylase activity", "Histone h3 methyl lysine 36 demethylase activity", "Histone h3 methyl lysine 4 demethylase activity", "Histone h3 methyl lysine 9 demethylase activity", "Histone h3 tri di methyl lysine 27 demethylase activity", "Histone kinase activity", "Histone lysine n methyltransferase activity", "Histone methyltransferase activity", "Histone methyltransferase activity h3 k36 specific", "Histone methyltransferase activity h3 k4 specific", "Histone methyltransferase activity h3 k9 specific", "Histone methyltransferase activity h4 k20 specific", "Histone methyltransferase binding", "Histone serine kinase activity", "Histone threonine kinase activity", "Hmg box domain binding", "Hormone activity", "Hormone binding", "Hormone receptor binding", "Hsp70 protein binding", "Hsp90 protein binding", "Hyaluronic acid binding", "Hyalurononglucosaminidase activity", "Hydro lyase activity", "Hydrolase activity acting on acid anhydrides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in cyclic amidines", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amides", "Hydrolase activity acting on carbon nitrogen but not peptide bonds in linear amidines", "Hydrolase activity acting on ester bonds", "Hydrolase activity acting on ether bonds", "Hydrolase activity acting on glycosyl bonds", "Hydrolase activity hydrolyzing n glycosyl compounds", "Hydrolase activity hydrolyzing o glycosyl compounds", "Hydroxymethyl formyl and related transferase activity", "I smad binding", "Identical protein binding", "Ige binding", "Immunoglobulin binding", "Immunoglobulin receptor binding", "Importin alpha family protein binding", "Inorganic anion exchanger activity", "Inorganic anion transmembrane transporter activity", "Inorganic diphosphatase activity", "Inorganic molecular entity transmembrane transporter activity", "Inorganic phosphate transmembrane transporter activity", "Inositol 1 4 5 trisphosphate 5 phosphatase activity", "Inositol bisphosphate phosphatase activity", "Inositol phosphate phosphatase activity", "Inositol polyphosphate 5 phosphatase activity", "Inositol tetrakisphosphate phosphatase activity", "Inositol trisphosphate kinase activity", "Inositol trisphosphate phosphatase activity", "Insulin binding", "Insulin like growth factor binding", "Insulin like growth factor i binding", "Insulin like growth factor ii binding", "Insulin like growth factor receptor binding", "Insulin receptor binding", "Insulin receptor substrate binding", "Integrin binding", "Interleukin 1 binding", "Interleukin 1 receptor binding", "Interleukin 2 receptor binding", "Interleukin 6 receptor binding", "Intermediate filament binding", "Intracellular calcium activated chloride channel activity", "Intraciliary transport particle b binding", "Intramembrane lipid transporter activity", "Intramolecular oxidoreductase activity", "Intramolecular oxidoreductase activity interconverting aldoses and ketoses", "Intramolecular oxidoreductase activity transposing c c bonds", "Intramolecular transferase activity", "Intramolecular transferase activity phosphotransferases", "Intronic transcription regulatory region sequence specific dna binding", "Ion gated channel activity", "Ion transmembrane transporter activity", "Ionotropic glutamate receptor binding", "Iron ion binding", "Iron ion transmembrane transporter activity", "Isocitrate dehydrogenase activity", "Isomerase activity", "Isopeptidase activity", "Isoprenoid binding", "Jun kinase binding", "Jun kinase kinase kinase activity", "K48 linked polyubiquitin modification dependent protein binding", "K63 linked polyubiquitin modification dependent protein binding", "Keratin filament binding", "Kinase activator activity", "Kinase activity", "Kinase binding", "Kinase inhibitor activity", "Kinase regulator activity", "Kinesin binding", "Kinetochore binding", "L alanine transmembrane transporter activity", "L amino acid transmembrane transporter activity", "L arginine transmembrane transporter activity", "L ascorbic acid binding", "L aspartate transmembrane transporter activity", "L glutamine transmembrane transporter activity", "L histidine transmembrane transporter activity", "L lactate dehydrogenase activity", "L leucine transmembrane transporter activity", "L lysine transmembrane transporter activity", "L ornithine transmembrane transporter activity", "L serine transmembrane transporter activity", "Lactate dehydrogenase activity", "Lactate transmembrane transporter activity", "Lamin binding", "Laminin 1 binding", "Laminin binding", "Large ribosomal subunit rrna binding", "Lbd domain binding", "Leucine zipper domain binding", "Leukotriene c4 synthase activity", "Ligand gated cation channel activity", "Ligand gated ion channel activity", "Ligase activity", "Ligase activity forming carbon carbon bonds", "Ligase activity forming carbon nitrogen bonds", "Ligase activity forming carbon oxygen bonds", "Ligase activity forming carbon sulfur bonds", "Ligase activity forming phosphoric ester bonds", "Lim domain binding", "Lipase activator activity", "Lipase activity", "Lipase binding", "Lipase inhibitor activity", "Lipid binding", "Lipid kinase activity", "Lipid phosphatase activity", "Lipid transfer activity", "Lipid transporter activity", "Lipopolysaccharide binding", "Lipopolysaccharide immune receptor activity", "Lipoprotein particle receptor activity", "Lipoprotein particle receptor binding", "Long chain acyl coa dehydrogenase activity", "Long chain fatty acid binding", "Long chain fatty acid coa ligase activity", "Long chain fatty acid transporter activity", "Long chain fatty acyl coa binding", "Low density lipoprotein particle binding", "Low density lipoprotein particle receptor activity", "Low density lipoprotein particle receptor binding", "Lrr domain binding", "Lyase activity", "Lys48 specific deubiquitinase activity", "Lys63 specific deubiquitinase activity", "Lysine acetylated histone binding", "Lysine n methyltransferase activity", "Lysophosphatidic acid binding", "Lysophosphatidic acid phosphatase activity", "Lysophospholipase activity", "Lysophospholipid acyltransferase activity", "M7g 5 pppn diphosphatase activity", "Macrolide binding", "Macromolecule transmembrane transporter activity", "Magnesium ion binding", "Magnesium ion transmembrane transporter activity", "Malate dehydrogenase activity", "Manganese ion binding", "Manganese ion transmembrane transporter activity", "Mannose binding", "Mannosidase activity", "Mannosyl oligosaccharide 1 2 alpha mannosidase activity", "Mannosyl oligosaccharide mannosidase activity", "Mannosyltransferase activity", "Map kinase activity", "Map kinase kinase activity", "Map kinase kinase kinase activity", "Map kinase kinase kinase kinase activity", "Map kinase phosphatase activity", "Map kinase scaffold activity", "Map kinase tyrosine serine threonine phosphatase activity", "Mdm2 mdm4 family protein binding", "Medium chain fatty acid coa ligase activity", "Membrane insertase activity", "Metal cluster binding", "Metal dependent deubiquitinase activity", "Metal ion proton antiporter activity", "Metal ion transmembrane transporter activity", "Metalloaminopeptidase activity", "Metallocarboxypeptidase activity", "Metallochaperone activity", "Metallodipeptidase activity", "Metalloendopeptidase activity", "Metalloexopeptidase activity", "Metallopeptidase activity", "Methyl cpg binding", "Methylated histone binding", "Mhc class i protein binding", "Mhc class ib protein binding", "Mhc class ii protein complex binding", "Mhc protein binding", "Mhc protein complex binding", "Microfilament motor activity", "Microtubule binding", "Microtubule minus end binding", "Microtubule motor activity", "Microtubule plus end binding", "Microtubule severing atpase activity", "Minor groove of adenine thymine rich dna binding", "Minus end directed microtubule motor activity", "Mirna binding", "Misfolded protein binding", "Mismatch repair complex binding", "Mismatched dna binding", "Mitochondrial ribosome binding", "Mitochondrion targeting sequence binding", "Mitogen activated protein kinase binding", "Mitogen activated protein kinase kinase binding", "Mitogen activated protein kinase kinase kinase binding", "Mitogen activated protein kinase p38 binding", "Modification dependent protein binding", "Modified amino acid binding", "Modified amino acid transmembrane transporter activity", "Molecular adaptor activity", "Molecular carrier activity", "Molecular function activator activity", "Molecular function inhibitor activity", "Molecular function regulator", "Molecular sequestering activity", "Molecular transducer activity", "Molybdopterin cofactor binding", "Monocarboxylic acid binding", "Monocarboxylic acid transmembrane transporter activity", "Monooxygenase activity", "Monosaccharide binding", "Mrf binding", "Mrna 3 utr au rich region binding", "Mrna 3 utr binding", "Mrna 5 utr binding", "Mrna binding", "Mrna methyltransferase activity", "Muscle alpha actinin binding", "Mutlalpha complex binding", "Myosin binding", "Myosin ii binding", "Myosin light chain binding", "Myosin v binding", "Myristoyltransferase activity", "N acetylgalactosamine 4 o sulfotransferase activity", "N acetyllactosamine synthase activity", "N acetyllactosaminide beta 1 3 n acetylglucosaminyltransferase activity", "N acetyltransferase activity", "N acylsphingosine amidohydrolase activity", "N acyltransferase activity", "N methyltransferase activity", "N6 methyladenosine containing rna binding", "Nad binding", "Nad dependent protein deacetylase activity", "Nad p h oxidase h2o2 forming activity", "Nad p plus nucleosidase activity", "Nad p plus protein arginine adp ribosyltransferase activity", "Nad retinol dehydrogenase activity", "Nadh dehydrogenase activity", "Nadh pyrophosphatase activity", "Nadp binding", "Nadp retinol dehydrogenase activity", "Nadph binding", "Nadplus adp ribosyltransferase activity", "Nadplus binding", "Nadplus kinase activity", "Nadplus nucleosidase activity", "Narrow pore channel activity", "Nedd8 specific protease activity", "Nedd8 transferase activity", "Nerve growth factor binding", "Neuregulin binding", "Neurexin family protein binding", "Neuroligin family protein binding", "Neuropeptide hormone activity", "Neuropeptide receptor activity", "Neuropeptide receptor binding", "Neurotransmitter binding", "Neurotransmitter receptor activity", "Neurotransmitter receptor regulator activity", "Neurotransmitter transmembrane transporter activity", "Neurotrophin binding", "Neurotrophin receptor activity", "Neurotrophin receptor binding", "Neurotrophin trk receptor binding", "Neutral amino acid transmembrane transporter activity", "Nf kappab binding", "Nfat protein binding", "Nitric oxide synthase binding", "Nitric oxide synthase regulator activity", "Nitrite reductase activity", "Non membrane spanning protein tyrosine kinase activity", "Non membrane spanning protein tyrosine phosphatase activity", "Notch binding", "Nuclear export signal receptor activity", "Nuclear import signal receptor activity", "Nuclear localization sequence binding", "Nuclear receptor activity", "Nuclear receptor binding", "Nuclear receptor coactivator activity", "Nuclease activity", "Nucleobase containing compound kinase activity", "Nucleobase containing compound transmembrane transporter activity", "Nucleobase transmembrane transporter activity", "Nucleocytoplasmic carrier activity", "Nucleoside binding", "Nucleoside diphosphatase activity", "Nucleoside diphosphate kinase activity", "Nucleoside kinase activity", "Nucleoside monophosphate kinase activity", "Nucleoside transmembrane transporter activity", "Nucleoside triphosphatase regulator activity", "Nucleoside triphosphate diphosphatase activity", "Nucleosomal dna binding", "Nucleosome binding", "Nucleotidase activity", "Nucleotide diphosphatase activity", "Nucleotide phosphatase activity acting on free nucleotides", "Nucleotide sugar transmembrane transporter activity", "Nucleotide transmembrane transporter activity", "Nucleotidyltransferase activity", "O acetyltransferase activity", "O acyltransferase activity", "O methyltransferase activity", "O palmitoyltransferase activity", "Oleate transmembrane transporter activity", "Oligopeptide binding", "Oligopeptide transmembrane transporter activity", "Oligosaccharide binding", "Oligosaccharyl transferase activity", "Omega peptidase activity", "Opioid receptor binding", "Opsonin binding", "Organic acid binding", "Organic acid sodium symporter activity", "Organic acid transmembrane transporter activity", "Organic anion transmembrane transporter activity", "Organic cation transmembrane transporter activity", "Organic hydroxy compound transmembrane transporter activity", "Organophosphate ester transmembrane transporter activity", "Oxidative phosphorylation uncoupler activity", "Oxidative rna demethylase activity", "Oxidized dna binding", "Oxidoreductase activity", "Oxidoreductase activity acting on a heme group of donors", "Oxidoreductase activity acting on a sulfur group of donors", "Oxidoreductase activity acting on a sulfur group of donors disulfide as acceptor", "Oxidoreductase activity acting on a sulfur group of donors nad p as acceptor", "Oxidoreductase activity acting on a sulfur group of donors oxygen as acceptor", "Oxidoreductase activity acting on ch oh group of donors", "Oxidoreductase activity acting on ch or ch2 groups", "Oxidoreductase activity acting on diphenols and related substances as donors", "Oxidoreductase activity acting on nad p h", "Oxidoreductase activity acting on nad p h heme protein as acceptor", "Oxidoreductase activity acting on nad p h oxygen as acceptor", "Oxidoreductase activity acting on nad p h quinone or similar compound as acceptor", "Oxidoreductase activity acting on other nitrogenous compounds as donors", "Oxidoreductase activity acting on other nitrogenous compounds as donors cytochrome as acceptor", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen nad p h as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced ascorbate as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced flavin or flavoprotein as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with incorporation or reduction of molecular oxygen reduced pteridine as one donor and incorporation of one atom of oxygen", "Oxidoreductase activity acting on paired donors with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water", "Oxidoreductase activity acting on peroxide as acceptor", "Oxidoreductase activity acting on single donors with incorporation of molecular oxygen", "Oxidoreductase activity acting on the aldehyde or oxo group of donors", "Oxidoreductase activity acting on the aldehyde or oxo group of donors disulfide as acceptor", "Oxidoreductase activity acting on the aldehyde or oxo group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors", "Oxidoreductase activity acting on the ch ch group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch ch group of donors oxygen as acceptor", "Oxidoreductase activity acting on the ch nh group of donors", "Oxidoreductase activity acting on the ch nh group of donors nad or nadp as acceptor", "Oxidoreductase activity acting on the ch nh2 group of donors", "Oxidoreductase activity acting on the ch nh2 group of donors oxygen as acceptor", "Oxidoreduction driven active transmembrane transporter activity", "Oxo acid lyase activity", "Oxygen binding", "Oxygen sensor activity", "Oxysterol binding", "P type calcium transporter activity", "P type potassium transmembrane transporter activity", "P type transmembrane transporter activity", "P53 binding", "Palmitoyl coa hydrolase activity", "Palmitoyl protein hydrolase activity", "Palmitoyltransferase activity", "Passive transmembrane transporter activity", "Pattern recognition receptor activity", "Pdz domain binding", "Pentosyltransferase activity", "Peptidase activator activity", "Peptidase activator activity involved in apoptotic process", "Peptidase activity", "Peptidase regulator activity", "Peptide alpha n acetyltransferase activity", "Peptide antigen binding", "Peptide binding", "Peptide hormone binding", "Peptide hormone receptor binding", "Peptide lysine n acetyltransferase activity", "Peptide n acetyltransferase activity", "Peptide receptor activity", "Peptide transmembrane transporter activity", "Peptidoglycan binding", "Peptidyl proline 4 dioxygenase activity", "Peptidyl proline dioxygenase activity", "Peroxiredoxin activity", "Peroxisome proliferator activated receptor binding", "Peroxisome targeting sequence binding", "Phosphatase activator activity", "Phosphatase activity", "Phosphatase binding", "Phosphatase inhibitor activity", "Phosphatase regulator activity", "Phosphate ion binding", "Phosphatidic acid binding", "Phosphatidic acid transfer activity", "Phosphatidyl phospholipase b activity", "Phosphatidylcholine binding", "Phosphatidylcholine floppase activity", "Phosphatidylcholine sterol o acyltransferase activator activity", "Phosphatidylcholine transfer activity", "Phosphatidylcholine transporter activity", "Phosphatidylethanolamine binding", "Phosphatidylethanolamine flippase activity", "Phosphatidylglycerol binding", "Phosphatidylinositol 3 4 5 trisphosphate 3 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 4 5 trisphosphate binding", "Phosphatidylinositol 3 4 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 3 5 bisphosphate binding", "Phosphatidylinositol 3 5 bisphosphate phosphatase activity", "Phosphatidylinositol 3 kinase activity", "Phosphatidylinositol 3 kinase binding", "Phosphatidylinositol 3 kinase regulator activity", "Phosphatidylinositol 3 kinase regulatory subunit binding", "Phosphatidylinositol 3 phosphate binding", "Phosphatidylinositol 4 5 bisphosphate 3 kinase activity", "Phosphatidylinositol 4 5 bisphosphate 5 phosphatase activity", "Phosphatidylinositol 4 5 bisphosphate binding", "Phosphatidylinositol 4 5 bisphosphate phosphatase activity", "Phosphatidylinositol 4 phosphate binding", "Phosphatidylinositol 5 phosphate binding", "Phosphatidylinositol binding", "Phosphatidylinositol bisphosphate binding", "Phosphatidylinositol bisphosphate kinase activity", "Phosphatidylinositol bisphosphate phosphatase activity", "Phosphatidylinositol kinase activity", "Phosphatidylinositol monophosphate phosphatase activity", "Phosphatidylinositol phosphate 4 phosphatase activity", "Phosphatidylinositol phosphate 5 phosphatase activity", "Phosphatidylinositol phosphate binding", "Phosphatidylinositol phosphate kinase activity", "Phosphatidylinositol phosphate phosphatase activity", "Phosphatidylinositol transfer activity", "Phosphatidylinositol trisphosphate phosphatase activity", "Phosphatidylserine 1 acylhydrolase activity", "Phosphatidylserine binding", "Phosphodiesterase i activity", "Phosphofructokinase activity", "Phospholipase a1 activity", "Phospholipase a2 activity", "Phospholipase a2 inhibitor activity", "Phospholipase activity", "Phospholipase binding", "Phospholipase c activity", "Phospholipase d activity", "Phospholipase inhibitor activity", "Phospholipid binding", "Phospholipid scramblase activity", "Phospholipid transfer activity", "Phospholipid transporter activity", "Phosphoprotein binding", "Phosphoprotein phosphatase activity", "Phosphoric diester hydrolase activity", "Phosphoric ester hydrolase activity", "Phosphorus oxygen lyase activity", "Phosphoserine residue binding", "Phosphotransferase activity for other substituted phosphate groups", "Phosphotransferase activity nitrogenous group as acceptor", "Phosphotransferase activity phosphate group as acceptor", "Phosphotyrosine residue binding", "Plus end directed microtubule motor activity", "Poly a binding", "Poly a specific ribonuclease activity", "Poly g binding", "Poly purine tract binding", "Poly pyrimidine tract binding", "Polynucleotide adenylyltransferase activity", "Polypeptide n acetylgalactosaminyltransferase activity", "Polysaccharide binding", "Polysome binding", "Polyubiquitin modification dependent protein binding", "Porin activity", "Potassium channel activity", "Potassium channel inhibitor activity", "Potassium channel regulator activity", "Potassium chloride symporter activity", "Potassium ion binding", "Potassium ion transmembrane transporter activity", "Pre mirna binding", "Pre mrna 3 splice site binding", "Pre mrna 5 splice site binding", "Pre mrna binding", "Pre mrna intronic binding", "Prenyltransferase activity", "Primary active transmembrane transporter activity", "Primary mirna binding", "Procollagen proline 4 dioxygenase activity", "Procollagen proline dioxygenase activity", "Profilin binding", "Proline rich region binding", "Promoter specific chromatin binding", "Protease binding", "Proteasome activating activity", "Proteasome binding", "Protein adp ribosylase activity", "Protein antigen binding", "Protein arginine n methyltransferase activity", "Protein arginine omega n asymmetric methyltransferase activity", "Protein arginine omega n monomethyltransferase activity", "Protein binding involved in heterotypic cell cell adhesion", "Protein c terminus binding", "Protein carboxyl o methyltransferase activity", "Protein carrier chaperone", "Protein containing complex binding", "Protein deacetylase activity", "Protein demethylase activity", "Protein dimerization activity", "Protein disaggregase activity", "Protein disulfide isomerase activity", "Protein disulfide reductase nad p activity", "Protein domain specific binding", "Protein folding chaperone", "Protein geranylgeranyltransferase activity", "Protein heterodimerization activity", "Protein homodimerization activity", "Protein kinase a binding", "Protein kinase a catalytic subunit binding", "Protein kinase a regulatory subunit binding", "Protein kinase activity", "Protein kinase b binding", "Protein kinase c activity", "Protein kinase c binding", "Protein lipid complex binding", "Protein macromolecule adaptor activity", "Protein membrane adaptor activity", "Protein methyltransferase activity", "Protein n terminus binding", "Protein phosphatase 1 binding", "Protein phosphatase 2a binding", "Protein phosphatase 2b binding", "Protein phosphatase activator activity", "Protein phosphatase binding", "Protein phosphatase regulator activity", "Protein phosphorylated amino acid binding", "Protein prenyltransferase activity", "Protein self association", "Protein sequestering activity", "Protein serine kinase activity", "Protein serine threonine kinase activator activity", "Protein serine threonine kinase activity", "Protein serine threonine kinase inhibitor activity", "Protein serine threonine phosphatase activity", "Protein serine threonine phosphatase inhibitor activity", "Protein serine threonine tyrosine kinase activity", "Protein tag", "Protein transmembrane transporter activity", "Protein transporter activity", "Protein tyrosine kinase activator activity", "Protein tyrosine kinase activity", "Protein tyrosine kinase binding", "Protein tyrosine kinase inhibitor activity", "Protein tyrosine phosphatase activity", "Protein tyrosine serine threonine phosphatase activity", "Protein tyrosine threonine phosphatase activity", "Proteoglycan binding", "Proton channel activity", "Proton transmembrane transporter activity", "Proton transporting atp synthase activity rotational mechanism", "Pseudouridine synthase activity", "Purine nucleotide transmembrane transporter activity", "Pyrimidine nucleoside transmembrane transporter activity", "Pyrimidine nucleotide binding", "Pyrimidine nucleotide sugar transmembrane transporter activity", "Pyrophosphate hydrolysis driven proton transmembrane transporter activity", "Pyruvate dehydrogenase acetyl transferring kinase activity", "Pyruvate dehydrogenase activity", "Pyruvate transmembrane transporter activity", "Quaternary ammonium group binding", "Quaternary ammonium group transmembrane transporter activity", "Quinone binding", "R smad binding", "Racemase and epimerase activity", "Racemase and epimerase activity acting on carbohydrates and derivatives", "Rage receptor binding", "Rdna binding", "Receptor antagonist activity", "Receptor tyrosine kinase binding", "Regulatory rna binding", "Retinal binding", "Retinal dehydrogenase activity", "Retinoic acid binding", "Retinoic acid receptor binding", "Retinoid x receptor binding", "Retromer complex binding", "Ribonuclease activity", "Ribonuclease p activity", "Ribonuclease p rna binding", "Ribonucleoprotein complex binding", "Ribonucleotide binding", "Ribose phosphate diphosphokinase activity", "Ribosomal large subunit binding", "Ribosomal protein s6 kinase activity", "Ribosomal small subunit binding", "Ribosome binding", "Rna 2 o methyltransferase activity", "Rna 7 methylguanosine cap binding", "Rna adenylyltransferase activity", "Rna binding", "Rna binding involved in posttranscriptional gene silencing", "Rna cap binding", "Rna directed dna polymerase activity", "Rna dna hybrid ribonuclease activity", "Rna methyltransferase activity", "Rna polymerase activity", "Rna polymerase binding", "Rna polymerase core enzyme binding", "Rna polymerase i general transcription initiation factor activity", "Rna polymerase i transcription regulatory region sequence specific dna binding", "Rna polymerase ii activity", "Rna polymerase ii c terminal domain binding", "Rna polymerase ii c terminal domain phosphoserine binding", "Rna polymerase ii core promoter sequence specific dna binding", "Rna polymerase ii ctd heptapeptide repeat kinase activity", "Rna polymerase ii ctd heptapeptide repeat phosphatase activity", "Rna polymerase ii general transcription initiation factor activity", "Rna polymerase ii general transcription initiation factor binding", "Rna polymerase ii intronic transcription regulatory region sequence specific dna binding", "Rna polymerase ii specific dna binding transcription factor binding", "Rna polymerase iii transcription regulatory region sequence specific dna binding", "Rna stem loop binding", "Rna strand annealing activity", "Roundabout binding", "Rrna adenine methyltransferase activity", "Rrna binding", "Rrna cytosine methyltransferase activity", "S acyltransferase activity", "S adenosyl l methionine binding", "S adenosylmethionine dependent methyltransferase activity", "S methyltransferase activity", "S100 protein binding", "Salt transmembrane transporter activity", "Scaffold protein binding", "Scavenger receptor activity", "Secondary active transmembrane transporter activity", "Selenium binding", "Semaphorin receptor activity", "Sequence specific dna binding", "Sequence specific mrna binding", "Sequence specific single stranded dna binding", "Serine hydrolase activity", "Serine transmembrane transporter activity", "Serine type carboxypeptidase activity", "Serine type endopeptidase inhibitor activity", "Serine type exopeptidase activity", "Sh2 domain binding", "Sh3 domain binding", "Signal recognition particle binding", "Signal sequence binding", "Signaling adaptor activity", "Signaling receptor binding", "Signaling receptor complex adaptor activity", "Signaling receptor inhibitor activity", "Signaling receptor regulator activity", "Single stranded dna 3 5 exodeoxyribonuclease activity", "Single stranded dna binding", "Single stranded dna endodeoxyribonuclease activity", "Single stranded dna exodeoxyribonuclease activity", "Single stranded dna helicase activity", "Single stranded rna binding", "Single stranded telomeric dna binding", "Sirna binding", "Smad binding", "Small molecule sensor activity", "Small protein activating enzyme binding", "Small ribosomal subunit rrna binding", "Snap receptor activity", "Snare binding", "Snorna binding", "Snrna binding", "Snrnp binding", "Sodium channel regulator activity", "Sodium chloride symporter activity", "Sodium ion binding", "Sodium ion transmembrane transporter activity", "Solute anion antiporter activity", "Solute bicarbonate symporter activity", "Solute cation antiporter activity", "Solute cation symporter activity", "Solute proton antiporter activity", "Solute proton symporter activity", "Solute sodium symporter activity", "Spectrin binding", "Sphingolipid binding", "Sphingolipid transfer activity", "Sphingolipid transporter activity", "Sphingomyelin phosphodiesterase activity", "Sphingosine 1 phosphate receptor activity", "Sphingosine n acyltransferase activity", "Steroid binding", "Steroid dehydrogenase activity", "Steroid dehydrogenase activity acting on the ch oh group of donors nad or nadp as acceptor", "Steroid hormone binding", "Steroid hormone receptor activity", "Sterol binding", "Sterol esterase activity", "Sterol transfer activity", "Sterol transporter activity", "Structural constituent of cytoskeleton", "Structural constituent of eye lens", "Structural constituent of muscle", "Structural constituent of nuclear pore", "Structural constituent of postsynapse", "Structural constituent of postsynaptic actin cytoskeleton", "Structural constituent of presynaptic active zone", "Structural constituent of ribosome", "Structural constituent of synapse", "Structural molecule activity", "Structural molecule activity conferring elasticity", "Succinate transmembrane transporter activity", "Sugar transmembrane transporter activity", "Sulfate binding", "Sulfate transmembrane transporter activity", "Sulfatide binding", "Sulfotransferase activity", "Sulfur compound binding", "Sulfur compound transmembrane transporter activity", "Sulfuric ester hydrolase activity", "Sulfurtransferase activity", "Sumo binding", "Sumo ligase activity", "Sumo specific protease activity", "Sumo transferase activity", "Supercoiled dna binding", "Superoxide dismutase activity", "Symporter activity", "Syndecan binding", "Syntaxin 1 binding", "Syntaxin binding", "T cell receptor binding", "Tap binding", "Tap1 binding", "Tat protein binding", "Tau protein binding", "Tau protein kinase activity", "Tbp class protein binding", "Telomerase activity", "Telomerase rna binding", "Telomeric dna binding", "Testosterone dehydrogenase nad p activity", "Testosterone dehydrogenase nadplus activity", "Tetrapyrrole binding", "Tfiib class transcription factor binding", "Tfiid class transcription factor complex binding", "Thiamine pyrophosphate binding", "Thioesterase binding", "Thiol oxidase activity", "Thiolester hydrolase activity", "Thioredoxin disulfide reductase activity", "Threonine type endopeptidase activity", "Threonine type peptidase activity", "Thyroid hormone receptor binding", "Thyroid hormone transmembrane transporter activity", "Titin binding", "Toll like receptor binding", "Toxic substance binding", "Tpr domain binding", "Transcription coactivator activity", "Transcription coactivator binding", "Transcription coregulator activity", "Transcription coregulator binding", "Transcription corepressor activity", "Transcription corepressor binding", "Transcription elongation regulator activity", "Transcription factor binding", "Transcription regulator activity", "Transcription regulator inhibitor activity", "Transferase activity transferring alkyl or aryl other than methyl groups", "Transferase activity transferring nitrogenous groups", "Transferase activity transferring one carbon groups", "Transferase activity transferring phosphorus containing groups", "Transferase activity transferring sulphur containing groups", "Transferrin receptor binding", "Transforming growth factor beta binding", "Transforming growth factor beta receptor binding", "Transition metal ion binding", "Transition metal ion transmembrane transporter activity", "Transketolase or transaldolase activity", "Translation activator activity", "Translation elongation factor activity", "Translation factor activity rna binding", "Translation initiation factor activity", "Translation initiation factor binding", "Translation regulator activity", "Translation regulator activity nucleic acid binding", "Translation repressor activity", "Translation repressor activity mrna regulatory element binding", "Translation termination factor activity", "Transmembrane receptor protein kinase activity", "Transmembrane receptor protein phosphatase activity", "Transmembrane receptor protein tyrosine kinase activity", "Transmembrane transporter binding", "Transporter activity", "Triglyceride lipase activity", "Tripeptide transmembrane transporter activity", "Trna binding", "Trna cytosine methyltransferase activity", "Trna guanine methyltransferase activity", "Trna methyltransferase activity", "Trna specific adenosine deaminase activity", "Trna specific ribonuclease activity", "Tropomyosin binding", "Tubulin binding", "Tumor necrosis factor activated receptor activity", "Tumor necrosis factor receptor binding", "Tumor necrosis factor receptor superfamily binding", "Type 1 fibroblast growth factor receptor binding", "Type 5 metabotropic glutamate receptor binding", "Type i transforming growth factor beta receptor binding", "U1 snrna binding", "U2 snrna binding", "U3 snorna binding", "U4 snrna binding", "U6 snrna binding", "Ubiquinol cytochrome c reductase activity", "Ubiquinone binding", "Ubiquitin binding", "Ubiquitin conjugating enzyme binding", "Ubiquitin ligase substrate adaptor activity", "Ubiquitin like modifier activating enzyme activity", "Ubiquitin like protein binding", "Ubiquitin like protein conjugating enzyme activity", "Ubiquitin like protein conjugating enzyme binding", "Ubiquitin like protein ligase activity", "Ubiquitin like protein ligase binding", "Ubiquitin like protein specific isopeptidase activity", "Ubiquitin like protein specific protease activity", "Ubiquitin like protein transferase activity", "Ubiquitin protein transferase activator activity", "Ubiquitin protein transferase inhibitor activity", "Ubiquitin protein transferase regulator activity", "Ubiquitin specific protease binding", "Ubiquitin ubiquitin ligase activity", "Ubiquitination like modification dependent protein binding", "Udp galactose beta n acetylglucosamine beta 1 3 galactosyltransferase activity", "Udp glucosyltransferase activity", "Udp glycosyltransferase activity", "Udp xylosyltransferase activity", "Unfolded protein binding", "Unmethylated cpg binding", "Uridine transmembrane transporter activity", "Uridylyltransferase activity", "Vascular endothelial growth factor activated receptor activity", "Vascular endothelial growth factor binding", "Vascular endothelial growth factor receptor 2 binding", "Vascular endothelial growth factor receptor binding", "Very long chain fatty acid coa ligase activity", "Vinculin binding", "Virion binding", "Vitamin b6 binding", "Vitamin binding", "Vitamin d binding", "Vitamin d receptor binding", "Vitamin transmembrane transporter activity", "Voltage gated anion channel activity", "Voltage gated calcium channel activity", "Voltage gated calcium channel activity involved in regulation of cytosolic calcium levels", "Voltage gated cation channel activity", "Voltage gated channel activity", "Voltage gated chloride channel activity", "Volume sensitive anion channel activity", "Water channel activity", "Water transmembrane transporter activity", "Wd40 repeat domain binding", "Wide pore channel activity", "Wnt protein binding", "Ww domain binding", "Xenobiotic transmembrane transporter activity", "Y form dna binding", "Zinc ion binding", "Zinc ion transmembrane transporter activity"], "available_proteins": ["AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "ALYREF", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP4M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOC1", "APOL2", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL8B", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C1QBP", "C1orf123", "C1orf35", "C2CD2L", "C2CD5", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC137", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCDC86", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC7", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPH", "CENPV", "CEP131", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT4", "CNOT7", "CNOT9", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMMD6", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS4", "COPS5", "COPS6", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAHD1", "FAM120A", "FAM129B", "FAM173A", "FAM208A", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FMR1", "FN3KRP", "FNBP1", "FNDC3A", "FNTA", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GAL", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GID4", "GID8", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLPH3", "GOLPH3L", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPRASP2", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C4", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS4", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRGQ", "IRS4", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIAA0391", "KIAA1147", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KNOP1", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRPAP1", "LRPPRC", "LRRC40", "LRRC41", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LZIC", "LZTFL1", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCOS", "MOCS1", "MOGS", "MON1A", "MORF4L1", "MOV10", "MPC2", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MPV17", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL49", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS6", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTF2", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFS1", "NFU1", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP35", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAWR", "PAX6", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDRG1", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PET100", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POLA1", "POLD1", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN2", "RMDN3", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "RTCB", "RTF1", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNE2", "TAB1", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TDRKH", "TECR", "TEFM", "TELO2", "TERF2IP", "TES", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFRC", "TGFBRAP1", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TMCO1", "TMED10", "TMED9", "TMEM109", "TMEM115", "TMEM165", "TMEM192", "TMEM201", "TMEM206", "TMEM30A", "TMEM38B", "TMEM43", "TMEM59", "TMEM70", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC26", "TTC4", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBL5", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRC1", "UQCRC2", "UQCRFS1", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMP1", "VPS16", "VPS18", "VPS25", "VPS28", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS4A", "VPS4B", "VPS50", "VPS72", "VRK1", "VRK2", "VTA1", "VWA8", "WARS", "WARS2", "WASF2", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR75", "WDR77", "WDR82", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WRN", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZDHHC13", "ZFPL1", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM1", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF512B", "ZNF598", "ZNF622", "ZNF638", "ZNF644", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC4", "ABCD4", "ABI1", "ACADVL", "ACAT2", "ACOT8", "ACOT9", "ACOX3", "ACP1", "ACP6", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAM17", "ADD1", "ADD3", "ADK", "AGK", "AGPS", "AHCYL1", "AIFM1", "AKT1", "ALDH1A2", "ALDH1B1", "AMOT", "ANXA7", "APLP2", "APP", "ARHGAP1", "ARHGAP10", "ARHGEF1", "ARIH1", "ASCC3", "ASNA1", "ATP13A1", "ATP2A2", "ATP5A1", "ATP5L", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "AURKA", "B3GALT6", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG6", "BAIAP2", "BAZ1B", "BAZ2A", "BBS4", "BCAS3", "BCL2L13", "BCR", "BECN1", "BICD2", "BLM", "BMS1", "C2CD2L", "CADM1", "CALCOCO1", "CAMK1", "CAMK2G", "CANT1", "CAPN2", "CAPN5", "CARM1", "CASK", "CBX3", "CD320", "CDC20", "CDC42BPB", "CDK1", "CDK2", "CDK4", "CDK5RAP3", "CENPH", "CEP131", "CEP290", "CERS2", "CHD4", "CHKA", "CHMP1A", "CHST14", "CHUK", "CIP2A", "CISD1", "CIZ1", "CLCN3", "CLCN7", "CLN5", "CLN6", "CLPP", "CLSTN3", "CNNM4", "COLEC12", "COPS2", "COPS4", "COX15", "COX2", "COX5A", "CPD", "CPT2", "CPVL", "CSK", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTSA", "CTTN", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAXX", "DCTN1", "DCTPP1", "DCUN1D4", "DDX20", "DDX56", "DGCR8", "DHCR24", "DHCR7", "DHX29", "DHX36", "DHX37", "DHX9", "DIEXF", "DNAJB12", "DNAJC10", "DNAJC2", "DNM3", "DOCK1", "DOCK7", "DVL2", "DYNC2H1", "ECD", "ECE1", "EEA1", "EED", "EFCAB14", "EHD4", "EIF2B2", "EIF4B", "EIF4H", "EIF5", "ELMO2", "EML4", "ENAH", "EPB41L2", "EPDR1", "EPHA7", "EPHX1", "ERAP1", "ERC1", "ERCC3", "ERCC6L", "ERGIC3", "EXO1", "EZH2", "EZR", "FAM129B", "FAM49B", "FECH", "FERMT2", "FGFR1OP", "FKBP7", "FKRP", "FLAD1", "FLII", "FLOT1", "FMR1", "FNBP1", "FNTA", "FRG1", "FTSJ3", "FUCA1", "FUCA2", "FXR1", "GAA", "GAK", "GAL", "GALNT1", "GBA", "GBF1", "GCC1", "GCC2", "GID4", "GID8", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLT8D1", "GMPPB", "GNG12", "GNS", "GOLGA2", "GOLGA5", "GPAM", "GPR107", "GSK3B", "GSR", "GUSB", "GYS1", "HAUS4", "HDAC1", "HDAC2", "HDGFL2", "HERC2", "HINT3", "HIP1", "HLA-A", "HLA-C", "HLA-F", "HLTF", "HMGB1", "HMGB2", "HMOX2", "HNRNPA0", "HNRNPA2B1", "HNRNPA3", "HNRNPD", "HOOK1", "HOOK2", "HOOK3", "HPS6", "HS1BP3", "HSD17B12", "HSD17B7", "HSP90AA1", "HSP90AB1", "ICMT", "IDH2", "IFIT5", "IGF2BP1", "IGF2BP2", "IGF2R", "IMPAD1", "INA", "INPP4A", "IPO5", "IQCB1", "IQGAP1", "IQGAP3", "ITGAV", "ITM2C", "ITSN2", "JAM3", "KARS", "KCTD21", "KDELR1", "KDM1B", "KDM2A", "KHDRBS1", "KHSRP", "KIAA1147", "KIF11", "KIF22", "KIF23", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KNSTRN", "LAMB1", "LANCL2", "LBR", "LGALS3", "LGALS3BP", "LGMN", "LLGL1", "LMBRD1", "LMNB2", "LNPEP", "LRPAP1", "LYAR", "M6PR", "MAN1A2", "MAN2B1", "MAPRE1", "MAPRE2", "MATR3", "MBOAT7", "MCAT", 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0.6662607465302498 0.4948187493576657 3.3732974430890796 4.074278380383408 0.9978722835718216 0.3450714604006198 0.0860283086374867 0.058039929090825 0.0444225207932621 0.0499487852123864 0.0006355875237301 +Sensorimotor neuropathy 13 40 2.757459445583457 0.0058252438628378 8.980582524271844 31.118932038834952 1.3016328701661894 0.3009249972125085 3.646997920951252 3.5836645053134393 1.2437208862143418 0.3260038325488978 1.0 0.0427950226871739 5.091578894306532e-05 0.00026590101721 0.000515507866575 +Cone shaped epiphysis 5 16 2.7444654140062914 0.0060609540733069 3.2063106796116503 11.87135922330097 0.0642421494677637 0.5491292316029612 1.8258284409306336 3.3100985667263836 0.8697998682944144 0.2760577132687285 0.0639068253026823 0.0333019544595367 0.1143886596739273 0.0593060830293246 0.0750518175373725 +Slowly progressive 12 58 2.731523251411245 0.0063042292417956 12.696601941747574 56.12378640776699 0.7411325364412068 0.522622208333598 5.310978564028389 4.912508033345017 0.8104226905999934 0.3549765630745758 0.1288517153850862 0.0217241970341978 0.0071683635616653 0.0117044098486948 0.0034326595266602 +Parkinsonism 9 31 2.6993254929572488 0.006948018401623 7.453883495145631 30.097087378640776 0.7249761134976155 0.4663275088289313 3.116711838694066 3.708464636913605 0.8967824567735009 0.3291722600978801 0.0890077655415831 0.061791584068653 0.0484942526286875 0.3438893788635541 0.1245789815791415 +Peripheral demyelination 7 19 2.695275265163081 0.007033050318038 4.524271844660194 16.973300970873787 0.9472740181618832 0.3208012027704231 2.3341893675900383 2.269845761985369 1.1784704386991718 0.3026863353342601 1.0 0.1644315705571846 0.0004434091565531 0.0002680304953179 0.0003978268193634 +Bulbar signs 4 14 2.6945313237335293 0.0070487700889925 4.888349514563107 12.016990291262136 1.527818207801298 0.1656113111527082 2.218011046873564 1.4803576942139227 1.2783367300196684 0.2344360472575242 0.0340030734974357 0.1403531442218371 0.0002256496047817 0.0009276346440678 0.0039537733222705 +Abnormal muscle fiber morphology 22 75 2.676117054543415 0.0074480627116897 17.78640776699029 68.04126213592232 1.263675841483234 0.3649599499596623 6.500784844979595 6.6307423444197315 1.1691802531751734 0.3853191125649093 0.1606841235198424 0.0398412828369274 0.0185751728548963 0.0159979186446051 0.0021200977308462 +Inability to walk 14 91 2.64667492150507 0.0081287452703548 16.66504854368932 84.69902912621359 0.4056115860733718 0.6149200897254583 7.231232270040466 7.352874018977716 0.8216232864046632 0.3415658846811537 0.0183894592899862 0.0137919690299658 0.0113965143675507 0.0505373960818359 0.0319553261960264 +Abnormal gallbladder morphology 4 34 2.637804536315836 0.008344466369385 7.478155339805825 31.075242718446603 0.4272058322069254 0.5481313499841369 3.2037612142007585 2.976716880674025 0.8468189606834012 0.3256570196959197 0.0720066970258468 0.2786952299090933 0.1398356665213448 0.0252514374511772 0.0496567653265115 +Aplasia hypoplasia involving the vertebral column 6 17 2.636260432607297 0.0083825368035175 4.679611650485437 14.847087378640778 0.8883735186508074 0.3527358077962234 2.3127489306396716 2.051146083169333 0.9597872998017484 0.2871451112966173 0.0454466093944714 0.0173338143393145 0.0628860756551618 0.0195417527514502 0.0043384264527958 +Distal muscle weakness 14 70 2.616394253158995 0.0088863885189505 13.99514563106796 64.27912621359224 0.378143548680081 0.6371085023737708 5.834278994576672 7.014703781301811 0.8046554605614199 0.3362876084172668 0.1532907968993005 0.0350541036074757 0.0152193623988927 0.0318747851990895 0.0075116389514392 +Dysphagia 39 144 2.5977718077875656 0.0093830826056704 26.58252427184466 132.13349514563106 0.525484494447878 0.6234130914808526 8.355016250174085 12.686440449515484 0.9112834521434876 0.3703513369566691 0.3259754205989025 0.2384303393600948 0.1267742273665874 0.5016774278544968 0.0026380869965558 +Supranuclear gaze palsy 7 20 2.5433185168738404 0.0109805082050193 5.186893203883495 19.1626213592233 0.8242716574954257 0.3183493558985887 2.2612229396433574 2.139608194404574 1.2188387108542005 0.2935859783151378 0.0412996615361356 0.1683799151698467 0.0528695758908991 0.2421879711614701 0.002448268499096 +Abnormal femoral neck morphology 16 43 2.5355306373984643 0.0112277106746583 9.25242718446602 36.74029126213592 0.6712343390867015 0.4697291762664369 3.621586968033212 4.796644044529848 0.9043918120717824 0.3346762025558714 0.1076735224939214 0.0131234591400192 0.0177198518564191 0.013435076878633 4.369977807645735e-05 +Impaired proprioception 17 48 2.5251039871555307 0.0115664058786728 9.813106796116504 38.25485436893204 1.0894904790984437 0.3853358407663543 4.186376779745541 5.223695147901442 1.052731732437443 0.3596256989246241 1.0 0.3503528550879276 0.0109507350240015 0.0063342661912929 0.0004305757320285 +Clumsiness 7 18 2.515118119845394 0.0118992509472619 6.75 20.57766990291262 0.9027704056640264 0.2559090219975202 2.4698423753801175 2.2221930931993956 1.527926415027724 0.282470536898918 1.0 0.0221752921749746 0.0112094197528849 0.0300192966842153 0.0022946198906289 +Abnormal peripheral myelination 10 35 2.507014162559021 0.0121755833110084 7.635922330097087 32.13592233009709 0.6742900044491671 0.4743014543601314 3.568806451618386 4.873244854452022 0.9969709958674222 0.3457305187498817 1.0 0.3283440482523609 0.0083128917166309 0.0157664629434176 0.0023995157256505 +Dysdiadochokinesis 4 15 2.500658640866905 0.0123962599425084 4.157766990291262 15.45388349514563 0.6684839389883598 0.4186205101687726 2.0089273726107977 1.5439545323865935 0.9784437725207784 0.3063164957116248 1.0 0.0098384095742339 0.003389670482849 0.0069928111010265 0.0181161163925661 +Proximal muscle weakness 20 65 2.4969378761998287 0.0125270900753196 14.951456310679612 61.769417475728154 0.5489884587613049 0.5295429242587456 5.9089016947638 6.961944869050214 0.9537081726509974 0.3546417916471885 0.1514332383712025 0.1585734488003576 0.1736761901802118 0.1580903162722315 0.000378709337631 +Limb muscle weakness 18 89 2.491181346647972 0.0127319116527802 17.839805825242717 80.70388349514563 0.4827776345811875 0.6059822076523635 6.801525240221059 8.816890479868707 0.7698087425405967 0.3425134280672268 0.0196350756368694 0.0154910711890239 0.0456665485201554 0.1230687424699142 0.0052221489664332 +Disproportionate short stature 10 27 2.485357482809853 0.0129421396944147 8.58252427184466 24.70145631067961 1.4449047806081987 0.2464238748623315 3.3320283680556178 3.793287097673045 1.0910515137563812 0.2952991105687103 0.0919783900673582 0.0656244339904668 0.2075521457010754 0.1676128084311925 0.0037949128027229 +Glomerulopathy 4 11 2.483875160846591 0.0129961359670585 2.820388349514563 9.96359223300971 0.665958332940798 0.3017859836474246 1.512655943869742 0.8764085521210618 1.2285906000166364 0.2785070215881056 1.0 1.0 1.0 0.0172025832638257 0.0043329575683166 +Biliary tract abnormality 7 30 2.482149344044698 0.0130592529635451 8.184466019417476 26.4004854368932 1.3038634098573934 0.2674323053300255 3.1080777089644696 2.335313487465734 1.3483489456318312 0.3101233364725878 1.0 0.2613604367755145 0.0228944934741309 0.0043231258251732 0.0035910021710753 +Incoordination 15 76 2.480622376534084 0.0131153234890812 15.859223300970871 69.11650485436893 0.6868183945924522 0.4621230815272417 5.5138472973140855 6.676725217396416 1.1752874861922693 0.3755559385684158 0.1689314300850081 0.0456051806117164 0.0055675441345863 0.0219741093976294 0.008611955136123 +Abnormal femoral neck head morphology 17 51 2.4612142742916325 0.0138467640691206 11.097087378640778 44.88834951456311 0.710356821644891 0.4647128189516342 4.081724752298962 5.521112188696193 0.9531654138623804 0.3489729073692786 0.1288517153850862 0.0217241970341978 0.0327594708813819 0.0339767723532767 0.000134963853031 +Abnormality of the peripheral nervous system 23 108 2.446171461562078 0.0144382318638431 21.851941747572816 100.3252427184466 0.4924736649059071 0.6070149484118681 7.60428603700104 12.016414489110195 0.8367540963076672 0.3602458415795309 0.2761114264321841 0.1612349501074486 0.061944177679841 0.0265878919846384 0.0093373556926212 +Foot dorsiflexor weakness 9 33 2.4336213150208263 0.0149486251516552 6.871359223300971 31.803398058252423 0.5722811231484813 0.5519136473671545 3.234440738423893 3.8012118796735064 0.7842026565791261 0.3226099174033894 0.0770367071136399 0.0473022522201117 0.1563084442837106 0.2645177746775517 0.0267628454277298 +Ectrodactyly 4 15 2.4310854104241635 0.0150536654656581 4.12378640776699 15.87864077669903 0.8198140763126681 0.3757221931635416 2.0209382693093176 2.284355849612238 1.0264971379648948 0.291688305539228 0.0506073598520428 0.0213334360876883 0.0105950719619242 0.0280832529132891 0.0824033164968481 +Lower limb amyotrophy 5 18 2.4301939978419163 0.0150907430095257 4.599514563106796 17.79854368932039 0.4204622424068837 0.5444570422467591 2.3436134570776987 2.274958191343983 0.848761300245189 0.3106630644747082 1.0 0.1916891885455893 0.3502020618548794 0.2961580697833918 0.0209086601360684 +Abnormality of the metaphysis 14 61 2.424187920278857 0.0153426639187423 9.87621359223301 51.49514563106796 0.3562011438392169 0.6166342982450355 4.530020385411355 8.226317920685393 0.7780483709827255 0.3214835918572445 0.1569948284742302 0.0374078266468448 0.0168415796705145 0.1790473090596397 0.0207090421591844 +Coxa vara 6 16 2.422851333877683 0.0153992271697882 4.310679611650485 13.54126213592233 0.853738655548226 0.4218003203060939 1.9720332330132235 1.9928869528934432 0.8140335419312188 0.3116542205645756 0.0433751782957271 0.0009206745696038 0.0068495888428019 0.0756846958642696 0.0135772679757234 +Abnormality of femur morphology 22 76 2.4164860236335226 0.0156711278457775 17.20873786407767 66.68203883495146 0.8363246416857221 0.4265359075043799 5.791282481104246 7.777760660479065 1.2398669594969238 0.3848538433547022 0.1914555591783933 0.0636528989765832 0.0381560843457456 0.0197776675024878 0.0001977388724683 +Abnormality of the pubic bone 2 9 2.404268243366264 0.0162048776348167 2.1529126213592233 7.37621359223301 0.2794853025075929 0.4953026963638984 1.3576165086643517 1.6770053154849467 0.8687687589179643 0.270539146196651 0.0277087127163546 0.1155957163384056 0.0251008323038497 0.0239571113561098 0.1303826157459173 +Shoulder girdle muscle weakness 7 17 2.399970693940266 0.0163963844862384 4.004854368932039 12.42233009708738 0.8387402263996985 0.3756529644451753 2.0785487207705367 2.2836026739757753 0.9187113892871612 0.2934865228782298 1.0 1.0 0.2709026461704186 0.1887844423268079 0.0001399534495659 +Increased connective tissue 4 8 2.399595098713287 0.0164132158113485 2.5145631067961167 7.502427184466019 0.8156544766596637 0.4080201432400869 1.4337409663669696 0.673704389121222 0.9233752682577614 0.3237190879475042 1.0 0.0858288536093336 0.1662183776826317 0.0101015401572799 0.0017585862412997 +Dysostosis multiplex 6 8 2.393414520004096 0.0166923704069839 3.983009708737864 7.990291262135922 0.4150973501220912 0.1595724105588133 1.65382835361071 1.246316090990369 1.8479195153421644 0.2123242141003258 1.0 1.0 0.1820374447866984 0.0014320459890063 3.958628609894661e-05 +Progressive gait ataxia 4 11 2.3730130053726155 0.0176436426641737 3.3810679611650487 11.0873786407767 0.9190295749650902 0.2658532875386696 1.7592835107251577 1.880439920211323 1.2434873962438642 0.2734996669217905 1.0 1.0 0.0199028792923938 0.0172025832638257 0.0043329575683166 +Visual loss 20 58 2.3625383940890603 0.0181502612672996 12.189320388349516 49.779126213592235 0.7709512625515322 0.4025114627500821 4.5744204921606055 5.175300864908489 1.242827263568942 0.3662286004483653 1.0 0.5237470911105582 0.0036659628903284 0.0351743267040848 0.0089298824095212 +Abnormal pyramidal sign 30 130 2.361903316726929 0.0181813831707116 26.563106796116504 122.74271844660194 0.5527646259993448 0.5786409997172964 8.955304229503513 10.063961484693186 0.8713904195746744 0.3609426954901026 0.2825226368009707 0.0535573976827186 0.0252276173278947 0.0633154488806721 0.0067949200114794 +Paresthesia 6 30 2.357576015954117 0.0183946887567525 5.66747572815534 23.635922330097088 0.7476018604198311 0.4719429115693522 2.535880467324221 3.039141242047335 0.8424234714329004 0.3217041155902614 1.0 0.0484553320209439 0.1596470307013262 0.0093312143417945 0.0287358226060079 +Dementia 17 60 2.3552571525257315 0.0185098913836803 17.021844660194176 58.19174757281554 0.9978727756866732 0.3214313161707923 5.814027938449679 5.568168011495494 1.793982160512653 0.3770196158976925 1.0 0.1357968236714454 0.0097820539875486 0.1138666570015389 0.0067512487471941 +Postural instability 2 16 2.3488003878242 0.0188340005859608 3.533980582524272 17.79126213592233 0.4509430795614677 0.5268149729159746 2.1579185133601717 2.125919871541916 0.8315457301240203 0.299833681390129 1.0 0.0303491574999332 0.0176589935056828 0.1641182363781922 0.5410497954439945 +Abnormal sella turcica morphology 4 10 2.3479974196068567 0.0188746520640394 2.1310679611650487 7.259708737864078 0.3527899633564624 0.3302362894597835 1.2627239108344035 1.5017879029535528 1.2692310088213898 0.2695913026312082 0.0192582327414155 0.0814971443263516 0.1581956798045988 0.0086586519898169 0.0013491401517078 +Heterogeneous 17 46 2.345634883694262 0.0189947043700438 10.235436893203884 42.58009708737864 0.5995354724013603 0.4531415918363276 4.134323127398932 5.0637577656341985 1.0306945905630256 0.3367867805298957 1.0 0.1373975853712186 0.0424124192461041 0.0185261544399266 0.000121209241499 +Ventricular arrhythmia 13 42 2.3416491880969423 0.0191987512466562 10.0 36.96601941747573 1.0415384316890377 0.3677574027458479 3.8522468541414527 4.8022861343455805 1.0152201826292362 0.3231502492090489 1.0 0.3805737292783386 0.0155736096963644 0.0352078323408286 0.0003600117972108 +Abnormal pericardium morphology 4 11 2.3369112498781472 0.0194437992697671 3.487864077669903 10.762135922330096 1.0304485268572945 0.2849705132346721 1.7172308655515107 1.695717994097398 1.0794817436655069 0.2735310781030822 1.0 0.1484538203623246 0.277861461810767 0.1975866021584996 0.0231294135439989 +Fibrous tissue neoplasm 4 19 2.328547543151064 0.0198830477954381 4.007281553398058 18.771844660194176 0.7807593365929368 0.4709469482958039 2.629637907140341 2.35787947663891 0.7789231837359674 0.3141870087871546 1.0 0.0284424316807039 0.0991796010672266 0.1524764865133537 0.1352992013633588 +Kinetic tremor 12 35 2.323103406357095 0.0201735980382442 7.529126213592233 33.79611650485437 0.3631432849810554 0.5795361764380887 4.109145165819634 3.278672544846394 0.8609997265928164 0.3286830429081078 1.0 0.3022964060814402 0.0356251920123848 0.1110881847348581 0.0035998655942762 +Babinski sign 17 91 2.320003571743724 0.0203406841204802 19.08009708737864 87.19902912621359 0.4494221734255122 0.5751659127226604 6.9223075443198026 7.569689110667714 0.8530342054419842 0.3513302291959216 0.2055782483369453 0.0170487305613109 0.0039191210477652 0.0318665248083252 0.0145542698581211 +Abnormality of the ribs 19 71 2.318804030462296 0.0204056645675847 15.46359223300971 63.26456310679612 0.6596881680500318 0.4822792711086646 5.162987649103379 7.327989071924885 1.0464354559452582 0.3722680363619953 0.1994274007609256 0.249454442152862 0.1295566607081719 0.1206209998356291 0.0022076316008824 +Limb girdle muscle weakness 10 28 2.31778806641995 0.0204608419862537 6.385922330097087 25.211165048543688 0.7046294396116228 0.4863231890570912 2.9011373520939956 3.1532956410624498 0.797735822235521 0.3186211542147555 1.0 0.2683427616475903 0.1301493724540318 0.2130027955338551 0.0012269776587721 +Hypertriglyceridemia 5 21 2.30787227974504 0.0210062412605409 5.08252427184466 22.097087378640776 0.0435863575346183 0.4916191610884998 2.958939956620716 2.3627964471399987 1.0185182655273417 0.3029865931668792 0.0557427329493798 0.2217755071466549 0.3982623430868609 0.135543868878084 0.0426924060067812 +Periventricular white matter hyperintensities 2 8 2.2936499340071936 0.0218106147075256 2.978155339805826 8.604368932038835 0.7206271937008832 0.2495118997135797 1.313488091366194 1.3113693798075805 1.4898193087366574 0.2872267653893681 1.0 0.0683810764565047 0.0086772133501052 0.0050923434600555 0.0336357980244025 +Muscle stiffness 8 22 2.282029852542516 0.0224875778450048 5.109223300970874 19.216019417475728 1.2530133657268057 0.2695837776665858 2.5817154639007844 2.4582801786037667 1.0397164239726309 0.2961148999712332 1.0 0.0275080115441885 0.0018110621800452 0.0102355224712358 0.0012203555248968 +Oromandibular dystonia 0 6 2.2818788923898228 0.0224964913423617 1.730582524271845 4.956310679611651 1.1882502597012077 0.2382412593757527 1.131086190944388 1.1979083634266432 0.9893427275402558 0.2482274576089271 0.0150080037348002 0.0639684350193291 0.1253337423142017 0.2897526236095206 0.5027345059494577 +Abnormal biliary tract morphology 6 26 2.2736693864256803 0.0229858721427238 7.427184466019417 23.174757281553397 1.329418499193971 0.249884151345828 2.8924137189053876 2.044064029481889 1.3393824039546371 0.2984385007787948 1.0 0.2217755071466549 0.0903561726908364 0.0087768454005906 0.0038055285280442 +Abnormal circulating lipid concentration 21 79 2.268173533011974 0.0233186319409635 21.0995145631068 75.44417475728156 1.321442689138656 0.3287247628796158 8.33534407984455 6.5596064623065375 1.4065018349702674 0.365722219395451 0.1716641165114558 0.0476143305524348 0.0826562920414128 0.0091393313419607 0.0002759800508016 +Amyotrophic lateral sclerosis 2 15 2.252353073414687 0.0242999687058911 4.453883495145631 16.203883495145632 1.0855969203541704 0.3037117925086244 2.3812188822255287 1.5445439412417563 1.0118111691913367 0.2917679915833991 0.0433751782957271 0.1762218760282218 0.3247664853085903 0.0756846958642696 0.1368997099058324 +Joint contracture of the hand 13 57 2.247507388913387 0.0246076188966879 9.33495145631068 47.52427184466019 0.6899528308551226 0.5319748768374064 4.138903957392258 6.987637711020041 0.8046601985034184 0.3400891059680895 1.0 0.2025113624557697 0.0881474282917187 0.1364029671177349 0.0498277241710053 +Demyelinating peripheral neuropathy 4 20 2.2411313802620456 0.0250175660728813 3.6189320388349513 16.41990291262136 0.8004175255851168 0.4261699448763591 1.908827430762096 2.446692237122478 0.9042326115295364 0.3171508979101954 1.0 0.1683799151698467 0.0004905065400264 0.0023124348467711 0.0106880220145335 +Postural tremor 8 21 2.2285650280589806 0.0258428601194995 5.194174757281553 17.851941747572816 1.214872214945056 0.2487017685351703 2.341305968762478 2.2981463861426747 1.2391489410765593 0.2821199379659175 1.0 0.1723099894081314 0.0063919517402272 0.0713646261968556 0.0005743066382168 +Muscle hypertrophy of the lower extremities 4 10 2.227818714426752 0.0258926063733968 2.0558252427184467 8.055825242718447 0.5668750819760063 0.4584615762503552 1.6203469748712638 1.290100488501096 0.8942414668325795 0.296643114491846 1.0 0.1239247827595126 0.23510055646516 0.4957890007184933 0.0103633783340074 +Abnormality of the shoulder girdle musculature 11 38 2.2269735552696504 0.0259490412279244 8.490291262135923 32.35436893203884 0.5120267959990212 0.5782002739476769 3.5822381289151823 3.8162472467536968 0.757059636123963 0.3268018099118617 1.0 0.3410083574355914 0.2040732901381184 0.1629443488297355 0.0034737383152492 +Positive romberg sign 4 11 2.217657367160845 0.0265782031862544 2.466019417475728 8.308252427184467 1.0733671875840938 0.3096488241780741 1.4485716699970723 1.6764009803624336 0.8283755892460324 0.2651507773538893 1.0 1.0 0.0086772133501052 0.0050923434600555 0.0005338561483377 +Premature rupture of membranes 2 6 2.217365613725116 0.0265981175069029 1.5631067961165048 5.800970873786408 0.9509293139272904 0.2937126614282376 1.1899245542912666 0.3992700002908385 1.068670600999266 0.275907562675117 1.0 0.04159641685533 0.0824659877424542 0.1973959389561772 0.00771353919978 +Distal lower limb amyotrophy 4 14 2.2084075353964865 0.0272158769874999 3.592233009708738 12.820388349514564 0.3170388535696535 0.5121622626127764 2.0009070428808444 1.5126559438697422 0.9487336668012136 0.3074093389028988 1.0 0.1239247827595126 0.23510055646516 0.1457934990596532 0.0103633783340074 +Impaired pain sensation 11 21 2.208146525807302 0.0272340606237633 4.41747572815534 18.885922330097088 0.2391400027582448 0.5987828788006049 2.578944887904309 1.8718911764554207 0.7990438621947193 0.2974699433254886 1.0 0.018891152845815 0.0681167311872175 0.0227330174276438 0.0660317196551079 +Abnormality of the calf 20 71 2.202723097386225 0.0276142712859279 12.466019417475728 60.16747572815534 0.3551043744963331 0.641248377140389 4.7230390372297135 7.636690334111997 0.7209068162102564 0.3201433210218154 0.1852054214439213 0.0115795614053247 0.1041310579962676 0.1694313606366218 0.0046192370255235 +Hammertoe 4 19 2.2003854228603026 0.0277795611798246 3.662621359223301 18.046116504854368 0.6966488433366873 0.4834332623162832 2.346296590711119 2.471254047837027 0.8432277041521599 0.3207676556555462 0.0423379310763625 0.0151070197534971 0.0553157666334183 0.0713646261968556 0.0120719478590556 +Beaking of vertebral bodies 4 9 2.200361451976652 0.0277812604977123 2.907766990291262 9.131067961165048 0.3586161575708288 0.4129848752927794 1.656478269216378 1.797329687366794 1.1037549452259698 0.2913355105961067 0.0213770889355645 0.0901405579438761 0.1741653971767485 0.0116756742779249 0.002252196025852 +Vascular skin abnormality 29 135 2.200118950727713 0.0277984566739195 24.946601941747577 116.29611650485435 0.7757412099244599 0.4861695283888829 8.070806982353375 12.284834935174542 1.190653202647226 0.3932244292288712 0.3191574090713369 0.2271437001334307 0.1161462679412713 0.1402175136863679 0.003490654696147 +Abnormality of extrapyramidal motor function 21 80 2.1993777086988984 0.0278510763213213 17.723300970873787 74.23058252427184 0.6611914449106878 0.5008095396366101 5.517064505158221 6.985611887807198 1.1554912414277594 0.3847143245763222 0.2003087356923018 0.2512059527024609 0.3096269152871024 0.3743026550183664 0.0221409656918479 +Gait ataxia 21 77 2.198657338738085 0.0279022965533082 14.351941747572816 68.35194174757281 0.6787136514518399 0.4783255809544575 5.256980668043156 6.678826209042067 1.046898326537344 0.3693668840587258 1.0 0.5438595681423013 0.0048206049280377 0.0184844040018815 0.0065157582264611 +Abnormal enchondral ossification 9 30 2.196065086322696 0.0280872851170053 8.825242718446601 28.097087378640776 0.9354465670440578 0.4238671948965085 3.7994051258084856 4.343870948544361 0.9586864854575652 0.3408490652683477 0.0890077655415831 0.3347057085815983 0.1971367302696896 0.6184885582877617 0.0235212982094472 +Disproportionate short limb short stature 7 22 2.189929446295508 0.0285293540350264 6.587378640776699 19.902912621359224 1.344701363676014 0.2682000023842777 2.8599402401133336 3.1206003999939886 0.9439707190715964 0.2973700803613334 0.0709977095462976 0.0406061543885706 0.1365892396200844 0.4912505524209553 0.0168669379700177 +Aplasia hypoplasia of metatarsal bones 3 11 2.189390117565704 0.0285684973238795 2.628640776699029 7.536407766990291 -0.4299942399234251 0.4878584556923697 1.502572259570389 1.964770968825546 0.8890353581824023 0.2926919915196673 0.0464807950830388 0.1878492321971458 0.3439334989552355 0.6593533907576883 0.1644709145443467 +Abnormality of the odontoid process 2 8 2.187563431334538 0.0287014180198874 1.8883495145631068 6.849514563106796 0.4809480703698225 0.3910181029813887 1.283638712356007 1.328066978835538 1.0241378212028085 0.2619757585976807 0.0213770889355645 0.0039064712270754 0.015225007352257 0.0116756742779249 0.01439805670462 +Abnormality of renal excretion 0 7 2.1866697830315363 0.0287666390227743 0.9854368932038836 6.776699029126213 0.6442154854600826 0.4742848097497059 1.381142608933526 0.6816889196715323 0.849303919889795 0.31439981627391 1.0 0.0987043131013681 0.1898352204968973 0.4160065505344545 0.6665596814409742 +Splenomegaly 24 98 2.1830881080887146 0.0290293221567918 20.660194174757283 86.74029126213593 0.5649049994066069 0.3835571498509289 6.419862077062851 7.868335701486235 1.546158503499524 0.3590721878602594 1.0 0.2967968168404439 0.1775733386534337 0.0533154245316304 0.0001445432079647 +Abnormal acetabulum morphology 7 24 2.180259029435273 0.029238266202936 4.415048543689321 19.133495145631063 0.4726113386657328 0.552884800435678 2.4014693616057 2.89024882482355 0.7710528054805144 0.3062917715013201 0.0598328352560405 0.236404668572991 0.4209558173560673 0.4015263058449369 0.0199020946739293 +Abnormal csf protein level 9 16 2.178790506627709 0.0293472345186915 4.434466019417476 12.20631067961165 1.1239853500963992 0.2260559983233297 2.11400242863219 2.084072511592451 1.241935948510828 0.248039542652958 1.0 0.1683799151698467 0.0059531349747588 0.0140312853386763 0.002448268499096 +Respiratory arrest 4 8 2.1773821157688795 0.0294520689293611 2.0558252427184467 7.070388349514563 1.3186130117670736 0.2232983865916446 1.389730031946098 1.4320861436977392 0.8270726521635177 0.2287950263954721 1.0 0.0814971443263516 0.1581956798045988 0.0688460117016781 0.0013491401517078 +Neck muscle weakness 5 18 2.175462005874245 0.0295955123144209 4.206310679611651 15.46359223300971 0.939049769317174 0.3360301393876674 2.1919222801274123 2.3742417714011115 0.9901989764800458 0.2887083620559018 0.0536916217909721 0.2143583684675494 0.0846123699035222 0.124643595331372 0.0362907856310389 +Hypothermia 4 12 2.158833332842774 0.0308630994768808 2.4174757281553396 9.49271844660194 1.0856169578047503 0.2588610618328691 1.611694349619475 1.8201795996814751 1.0634596616937388 0.2538467530049644 1.0 0.1029565435856987 0.0012875484046766 0.0172025832638257 0.0043329575683166 +Hypoplasia of the odontoid process 2 7 2.1535678377481293 0.0312740787719234 1.7135922330097086 5.849514563106796 0.7084033927132167 0.339821590839337 1.2308769108438145 1.328066978835538 1.0561070911915744 0.2674195088010785 0.0181972414506333 0.0028214739728005 0.0111011801010317 0.0073447144383531 0.0079370796506279 +Clonus 9 38 2.1532443836427366 0.0312994771917196 8.04611650485437 31.93446601941747 0.5828978309354407 0.490454230151838 3.78619227044226 4.424455038167712 0.8696948910263331 0.3203390008180061 0.0850331895047633 0.0568079337981731 0.0431051081708364 0.3173461003371735 0.0062283989950113 +Increased cerebral lipofuscin 4 6 2.145028960086657 0.0319505315868209 3.0970873786407767 5.118932038834951 1.0434065701738664 0.1270836154757583 1.1278862704044743 0.4599818751628888 1.7720117842909846 0.2267161680252343 1.0 0.0461123069087121 9.54357461344528e-05 0.0014684283121974 5.489393781591606e-05 +Abnormality of tibia morphology 1 16 2.138770161372847 0.0324542871647433 3.0776699029126213 13.29126213592233 0.3891104215011284 0.5830096967328335 2.0009188199538785 2.2268488248119382 0.7650623983336935 0.2999186633696579 0.0608528410554385 0.0303491574999332 0.105191413992555 0.410005165463368 0.7809920653374453 +Rhizomelia 6 13 2.137767690750422 0.0325356025021938 4.276699029126213 11.868932038834952 1.3783619481702345 0.228956695884812 2.09278482575067 1.6655579622091714 0.936017394236602 0.2616202806826952 0.048546111259079 0.019691222561341 0.0707844675435839 0.3051232152156647 0.0063580922287898 +Abnormal epiphysis morphology of the phalanges of the hand 1 9 2.133907204051206 0.032850377660456 2.4271844660194173 7.805825242718447 -0.3001983754522488 0.5463176340775688 1.5271137936603878 1.7435498463041632 0.8167686336073587 0.2820589934391418 0.0298109635380268 0.1239247827595126 0.23510055646516 0.4957890007184933 0.3982984602367481 +Short nail 3 6 2.1247278385373325 0.0336093291536219 1.5946601941747574 4.990291262135922 0.8281151844707718 0.3406921792672602 1.016022432607237 0.7372889940840268 0.9280165491339682 0.2589439848544906 1.0 0.04159641685533 0.0824659877424542 0.1973959389561772 0.0005732271800539 +Difficulty walking 15 86 2.1241090673545298 0.0336610244795538 15.580097087378642 75.13106796116504 0.4697839455005359 0.5877808014506588 5.810176207602449 9.191717769736409 0.8615188656802858 0.3499503569147802 0.0209159663585525 0.0775528091516589 0.0514158517497285 0.1409264416521256 0.0539000148297921 +Abnormal vascular physiology 23 56 2.118728670074335 0.0341134039461954 12.74757281553398 50.021844660194176 0.816183607478715 0.4136638745601454 4.907827009322534 5.622165606934028 1.2216480011219424 0.371091913776798 1.0 0.5589253676251454 0.4894004644804887 0.0566742341902793 0.0407877490659717 +Polyneuropathy 7 20 2.1065071962282653 0.0351603186801681 5.689320388349515 18.633495145631063 1.1475655107151586 0.297256939859202 2.871111980426299 2.8359934163787166 1.1251440285742276 0.3008764483611514 1.0 0.2180755491779121 0.0014691652083679 0.0081044088621321 0.039409055534926 +Frequent falls 9 46 2.103179315244564 0.0354500977208487 8.643203883495145 38.75485436893204 0.6268988624161936 0.4831027569691007 4.0086529499315136 3.828305504664436 1.0909180744790496 0.3651237988976172 0.0890077655415831 0.061791584068653 0.0090185147564143 0.0566012047710065 0.0086796345032239 +Abnormal upper motor neuron morphology 0 9 2.096812412735898 0.0360101843465621 2.104368932038835 10.152912621359222 0.6668580581129538 0.4264480473015415 1.810508789672501 1.2708136152843803 0.93546763978058 0.305632736845798 0.0192582327414155 0.0814971443263516 0.1581956798045988 0.3559534457378639 0.5927878722461318 +Abnormal rib cage morphology 22 84 2.095949009281473 0.0360867144975791 17.694174757281555 75.7135922330097 0.5488633555797945 0.5379800174608891 5.594611229067785 9.71314341791714 0.9782995531616954 0.3690468558866111 0.2415899364158828 0.3351389361963762 0.220516353558107 0.1586224886319643 0.0028640342055106 +Proportionate short stature 9 37 2.094555974906338 0.036210482277738 8.20873786407767 34.116504854368934 0.7111768198576495 0.4559300049156646 3.388318218343798 3.7920483254309434 0.966379822462628 0.3393663702605685 0.1096179734379608 0.0901677189318956 0.0817709134109805 0.1164819330840205 0.0351413027881584 +Abnormal epiphyseal ossification 6 17 2.090155947011746 0.0366037933369844 6.451456310679611 16.274271844660195 1.1227269321938518 0.3276999393402902 3.140724178369711 2.4155680760400804 1.043634905787503 0.3148370578580727 0.0464807950830388 0.1878492321971458 0.3439334989552355 0.6593533907576883 0.0049481295197396 +Hyperlipidemia 9 30 2.0876018541621044 0.0368337646146541 7.682038834951456 29.6626213592233 0.5392307404617857 0.3728005101645487 3.9693446328110418 2.956030683250849 1.27614168259521 0.3117729697341341 0.0740216838689131 0.2855170484549717 0.4939128229902693 0.02815445047553 0.0021618403257682 +Contractures of the joints of the upper limbs 16 82 2.0827027078307045 0.0372783304828101 15.5873786407767 70.82038834951456 0.961917368584866 0.453560490665382 5.296970733704175 9.19591360516456 0.9682537043334576 0.378553967263451 0.2142906638899178 0.085412898243946 0.0594071789271723 0.0870972014124965 0.0413146143583579 +Segmental peripheral demyelination remyelination 3 7 2.0826754662974727 0.0372808151891923 1.6601941747572817 4.737864077669903 1.1231406516527276 0.2457358043386077 1.1021021225411718 1.375663406058269 1.1869683790120098 0.2709829643602553 1.0 0.0550816697898294 0.0001725606130307 0.0001405335592956 0.0020033682110678 +Metatarsus adductus 5 15 2.0799706475419173 0.0375282252227002 3.7694174757281553 13.25 0.9957104022100554 0.3572272245833284 1.816252583500775 2.104808410901558 0.7948300017734555 0.2882447196496276 1.0 0.1444128696349771 0.0390718495583504 0.0444854600227105 0.0046379242911556 +Microcytic anemia 1 10 2.076335434422485 0.0378629382272803 2.441747572815534 8.526699029126213 0.6645628317552182 0.3838242289014166 1.6704179043327654 1.438636684975842 1.0496853438983738 0.3012783873714112 0.0245475710798989 0.0051552423978184 0.0199028792923938 0.1053546389470493 0.0986013223955862 +Cone shaped epiphyses of the phalanges of the hand 1 8 2.07011514377205 0.0384415630702816 2.308252427184466 7.257281553398058 -0.3124736202106239 0.5448272053811127 1.4277519346041712 1.5460002852175456 0.8175382706277232 0.2844815837841378 0.023491782758132 0.0987043131013681 0.1898352204968973 0.4160065505344545 0.2906426697670494 +Aplasia hypoplasia involving the pelvis 6 17 2.0692000361874725 0.0385273193339592 4.135922330097087 14.990291262135925 0.5037927429774518 0.5536877520898601 2.135227159600027 2.483909952681547 0.7387647396541343 0.3034231079358344 1.0 0.1955113655682517 0.0707844675435839 0.0989248704147511 0.0230912453221162 +Cognitive impairment 45 185 2.068733897004543 0.0385710644856414 40.38834951456311 166.01456310679612 0.9678903819313606 0.4602309002251459 12.35477425089026 15.27402711863426 1.6121748345734526 0.4202585511538368 0.3915090301507599 0.0592369594216207 0.0103066506978351 0.0126318809826866 0.0069730381280603 +Metaphyseal striations 1 5 2.0624867704274163 0.0391614158092332 1.300970873786408 5.247572815533981 1.010217520882931 0.3307806984352505 1.0528274594376033 0.9460541108309968 0.8938491735917876 0.283997233679671 1.0 0.04159641685533 0.003087611696091 0.0186627473263165 0.0677640175569944 +Disproportionate short trunk short stature 2 6 2.061566535061201 0.0392490228416939 1.5218446601941749 4.983009708737864 0.4124275912660306 0.360786721341216 0.9306060741204804 1.0713400871945435 1.1869525657580595 0.284085703465065 0.0213770889355645 0.0901405579438761 0.1741653971767485 0.0116756742779249 0.0705348016344186 +Ovarian cyst 7 18 2.06011948563364 0.0393871194994777 4.757281553398058 15.936893203883496 0.2524918724982314 0.6315163550900323 2.230486121499843 1.9745708783538596 0.6953142600914907 0.2837789110044018 1.0 1.0 1.0 0.4015263058449369 0.0575078377952935 +Abnormal head movements 4 13 2.058685659314753 0.0395243608892503 2.5364077669902914 11.169902912621358 0.5053434899767821 0.4737619042111583 1.7504880619659493 1.2600150215976438 0.917309643882884 0.3035134891578949 0.0256023215689562 0.1071891284628969 0.2052107238795277 0.4439075633632242 0.0052582215982291 +Hemolytic anemia 3 35 2.048861934262668 0.040475617487379 8.157766990291263 32.49757281553398 -0.1266357351200049 0.6423692300829941 5.179483692835344 2.669950352623546 0.7573670800608302 0.3000804589155379 0.0790417615704134 0.0496186824069471 0.0058546728506797 0.1110881847348581 0.0757419688955735 +Short thorax 2 8 2.0485890020253827 0.0405023209751411 1.4466019417475728 4.388349514563107 -0.1110996207895049 0.4830818941871314 1.0495320764101044 1.8340522787899791 1.0825316163065684 0.3067462572361881 0.0308605386170308 0.1280604643503683 0.2423974925429197 0.5079876539292768 0.1652047572335966 +Lumbar hyperlordosis 4 19 2.038755164017936 0.041474469144578 4.703883495145631 17.733009708737864 0.0631116732140608 0.7020097992276326 3.00883560776955 2.6220827839943066 0.6343496708571328 0.2737052257127178 0.0588118224393481 0.2327728239456267 0.4153631372956372 0.3929907866903629 0.1352992013633588 +Abnormal ovarian morphology 11 35 2.037957368150425 0.0415541965478436 7.20873786407767 27.8495145631068 -0.066971010364278 0.7500485496422341 3.53692331869843 3.523385777510966 0.5298336527091101 0.2459583431786003 1.0 1.0 1.0 0.2583585694619627 0.0761326596447121 +Limb ataxia 13 26 2.0366420228381177 0.04168592838966 6.597087378640777 24.114077669902912 0.989869123864314 0.3154216467413447 2.5039369509835696 2.8496458430585005 1.1323309577692284 0.292147514752726 1.0 0.2436179272361805 0.0184792322064663 0.053649406266927 0.0073872398636599 +Ventricular hypertrophy 15 46 2.035176642982403 0.0418331023510392 10.04126213592233 36.45873786407767 1.1361758135608295 0.3518404639351837 4.440080726024568 4.153106961798495 1.0569836433105884 0.3376234863759063 1.0 0.3626106066392318 0.2285461090114013 0.0271532501248917 0.0006565100691227 +Abnormal social behavior 19 72 2.0351509201419624 0.041835689721694 16.796116504854368 65.80339805825243 0.6678301735588785 0.4940185804874849 5.994105880514205 6.839540104535511 1.1033956384068455 0.3774724921329495 1.0 0.5416665853033574 0.0709513936905264 0.0178380374686823 0.0025804138601819 +Abnormal exteroceptive sensation 10 60 2.0343627460519693 0.0419150350868842 10.759708737864075 52.02427184466019 0.4941713240335635 0.5557419524937993 3.9194595318694754 5.696566262954939 0.9102536370390476 0.3437672640084617 1.0 0.0274501796920896 0.0433617035599321 0.0064629825009123 0.0177368507309666 +Pericarditis 1 6 2.033729088512833 0.041978917618441 1.5412621359223302 4.808252427184466 1.0465356013883245 0.3273693330411259 1.0523881114446327 0.8152847226576512 0.8192491618381674 0.278983410545408 1.0 0.0639684350193291 0.1253337423142017 0.0435926191526008 0.1462762019757018 +Deep palmar crease 2 12 2.0309945523894664 0.0422555472194905 3.866504854368932 11.75728155339806 0.5990239856383347 0.4998099821006278 1.9281120141985588 1.1231545330869228 0.7799394834925686 0.2989134885739745 1.0 0.1029565435856987 0.1975594178204269 0.0172025832638257 0.0986013223955862 +Abnormal lung lobation 6 15 2.029728283841065 0.0423841662541903 3.266990291262136 13.402912621359222 0.8057824047211188 0.4237226990881645 1.8647412350490211 1.7258152040640289 0.8098324555644494 0.3032019531807652 1.0 1.0 1.0 0.5539124029112868 0.0205229364106292 +Bowing of the legs 18 61 2.029697858432604 0.0423872607318904 11.155339805825244 51.15533980582524 0.3696320760225168 0.6089630438985444 4.432902753984072 6.8301264136382995 0.7679030342482581 0.32405716235975 0.1505030705182083 0.0333414242092628 0.1713319848886266 0.1547075519871022 0.0025543221558744 +Slurred speech 3 10 2.0284520863836195 0.0425141287049446 2.45873786407767 8.864077669902912 0.5323927403653204 0.4147809462031548 1.4075891250208603 1.616351781434359 0.9973486618272436 0.2852319096618858 1.0 0.1239247827595126 0.23510055646516 0.1457934990596532 0.0448872219881859 +Abnormal circulating dicarboxylic acid concentration 11 45 2.020924955157642 0.0432875341580361 9.611650485436892 41.19660194174757 0.3636351001240374 0.5903090665886829 4.629439374954948 2.5633125009393525 0.8124485448597606 0.3243501761394795 1.0 0.2956314809635333 0.1563084442837106 0.0087565646797269 0.0002142043583912 +Psychomotor deterioration 2 9 2.01952803611436 0.0434323663475075 3.2645631067961167 8.910194174757281 0.9753014938956188 0.1960965459818884 1.3866235282600423 0.7031088807706056 1.4929387846379636 0.2609606457365817 1.0 0.0595353304203936 0.0002227826640135 0.0033170374819039 0.0027834726260547 +Waddling gait 9 30 2.0190512660934363 0.0434818913462489 6.95873786407767 25.521844660194176 0.2885156831085541 0.6155321868729282 3.188380962854732 3.5529296669914525 0.7790885579761687 0.3131917525797651 0.0860283086374867 0.3251409200136808 0.5491527241905032 0.1403572550086468 0.0190847870201007 +Muscle fiber atrophy 3 22 2.0183783873301104 0.0435518685199822 5.444174757281553 20.281553398058257 0.7686173455615849 0.4552894087545087 2.6272082803045267 1.888480540541262 0.8113647632820095 0.320700919049039 0.048546111259079 0.1955113655682517 0.356411341728891 0.3051232152156647 0.1838658218206393 +Progeroid facial appearance 3 8 2.0177091064512505 0.0436215658662462 1.9514563106796117 7.388349514563107 0.6729672370065056 0.4005004632419714 1.5383678198214228 0.8728149940061183 0.919017314256916 0.2770141329353056 1.0 1.0 1.0 0.0621585272883563 0.0079370796506279 +Abnormal circulating bilirubin concentration 7 29 2.014837644020873 0.0439216633222425 6.611650485436893 26.725728155339805 0.4812850312626911 0.5974382444384296 3.1729530813550246 1.934615238303275 0.7143081068469757 0.3163768833940157 1.0 0.2143583684675494 0.0846123699035222 0.0341229578056568 0.0029760556157756 +Hyporeflexia 33 132 2.014623148925593 0.0439441500720942 24.893203883495147 117.84466019417476 0.3388981696864538 0.6807476655296206 8.619139485081204 12.383050804007432 0.6612068814470962 0.322700334971128 0.2672109652299364 0.148871059656874 0.0184358009193621 0.0202193596714493 0.0006534285487097 +Deformed sella turcica 2 7 2.0106654693989023 0.0443608036946012 1.449029126213592 4.361650485436893 0.6519584745232953 0.4108786670869809 1.0702617541763486 1.191712968868623 0.98030484078304 0.3007326817007539 0.0128766161439974 0.0550816697898294 0.1084298440104649 0.032628233248221 0.0181181417645757 +Short long bone 11 42 2.0100668374763004 0.0444241153587605 8.308252427184467 34.19660194174757 -0.0378013390730227 0.67126826940319 3.594039004165784 6.643683627515725 0.6507460925720548 0.2694429270638558 0.1560702041933742 0.5237470911105582 0.7774765754304399 0.5222016813966184 0.0777917519036925 +Hepatic failure 6 54 1.999769606377478 0.0455251479775484 12.25242718446602 48.050970873786405 0.7424989852941342 0.3814651163177168 5.527018274076851 5.448329576476532 1.3577793424610205 0.3539023729255708 0.1047496072339571 0.0831018560335817 0.0160938652494134 0.1001831762965923 0.2276349613458341 +Abnormal femoral head morphology 6 21 1.9978787842814745 0.0457298032562791 4.766990291262136 19.152912621359224 0.413732217448948 0.5208945987431343 2.434397050586806 3.05426905786014 0.8561972559864264 0.3026636075880872 0.0567667721825774 0.0265864003984115 0.0932703984994284 0.0408612650970917 0.0461426336925489 +Scotoma 8 16 1.9973694196014125 0.0457850672659603 4.189320388349515 12.196601941747574 1.1271039056750725 0.2779036999445621 2.1128553643245884 2.0698220238662226 1.1901076059375446 0.2884356618441315 1.0 1.0 0.0063919517402272 0.0713646261968556 0.1281606076495765 +Aplasia hypoplasia of the uterus 1 17 1.9940565193907496 0.046145878225877 4.155339805825243 16.521844660194176 0.1457063224911927 0.6576107308247001 2.9592943318947555 1.0437090763539998 0.6604266199992537 0.2727046107771668 1.0 1.0 0.2915824887707032 0.2153304097941032 0.5285934799942653 +Abnormal circulating sulfur amino acid concentration 3 10 1.992322881598856 0.0463356426971297 2.3907766990291264 8.308252427184467 0.3736594078798615 0.5346645440831289 1.5657785614622313 1.004663811020244 0.8517228747142751 0.3009438804020233 1.0 1.0 0.1419203898220533 0.0004788146962384 0.00630824692371 +Motor deterioration 1 6 1.9905526090012635 0.0465300947682219 1.3907766990291262 5.179611650485437 0.1463978452048765 0.3866087159912587 1.3016838902501162 0.4944074070400956 1.163792695642709 0.2820064237403191 1.0 0.0595353304203936 0.1169218221283287 0.2721697661507766 0.129364196063302 +Metaphyseal widening 7 24 1.9902425899382663 0.0465642187749548 4.62621359223301 19.76941747572815 0.419010320871322 0.5510828935226119 2.3854519087056207 4.095668639234996 0.7907560478881603 0.2978885709062411 0.0608528410554385 0.0303491574999332 0.0176589935056828 0.0509365284789281 0.0066608970268297 +Abnormal pupil morphology 1 13 1.9893912456857288 0.0466580351699406 2.6966019417475726 11.87135922330097 0.2351614224400204 0.5711344441918288 2.188382411603078 1.6708393033905853 0.8189584503986096 0.2942387104850355 1.0 0.1604648724397155 0.0480988323617951 0.224257489169728 0.5434948789645544 +Short clavicles 2 9 1.9814798020093525 0.0475374922539129 2.2864077669902914 9.33252427184466 0.1078349916904043 0.5887638994693714 1.8487754301179025 1.287961600499927 0.729259204829435 0.2483316410765342 1.0 1.0 1.0 0.4439075633632242 0.1088149775417643 +Adrenal hypoplasia 2 8 1.9813021979330308 0.0475573940560318 1.8519417475728157 8.186893203883495 0.3852327899897437 0.5464880134936936 1.550108394739415 1.256641794723172 0.7382232570467291 0.2693753067389556 1.0 1.0 1.0 1.0 0.0888008652079453 +Anarthria 0 6 1.9812835670949027 0.0475594821800751 1.3131067961165048 6.509708737864078 0.7919989281491029 0.3725746548429688 1.0710321028305447 0.7679267970658434 0.9858894880388938 0.2988917867777952 0.0139428334678447 0.0595353304203936 0.1169218221283287 0.2721697661507766 0.4772731985221821 +Hyperintensity of cerebral white matter on mri 4 21 1.9778160307538992 0.0479494643574121 5.844660194174757 19.76456310679612 0.5239793769920946 0.3497882694217939 2.383223245915457 2.1845455756818453 1.3844482033830876 0.3203944687906004 1.0 0.1916891885455893 0.0681167311872175 0.0940672040532474 0.0660317196551079 +Abnormal bone structure 47 195 1.977507881256764 0.0479842505414755 37.41747572815534 174.03398058252426 0.5052466892255619 0.6451089511590872 11.181012226303604 17.857684720378465 0.8786021869184294 0.373142151762858 0.4301974242082971 0.0891522955474903 0.110059521755185 0.2453020324571511 0.0030331411550109 +Abnormality of the upper respiratory tract 22 110 1.9771095453299767 0.0480292490560243 19.66504854368932 95.80582524271844 0.4534569687157453 0.5959175600884278 6.924659870205313 10.36312380503997 0.9632839800839448 0.3651113920771414 0.276915665834251 0.7576647661380898 0.5381137404977573 0.1787907549220724 0.017853813532958 +Abnormality of epiphysis morphology 18 65 1.972089347393312 0.0485994078148876 14.885922330097088 57.24757281553398 0.6699051414631522 0.4959188251133739 5.664066249559964 8.729587504130462 1.029966158611096 0.3689041276003297 0.1878894102306136 0.2267486508979282 0.273219723871911 0.3141341695699876 0.0117371343252047 +Abnormal form of the vertebral bodies 29 94 1.9702054277668084 0.0488148317451506 19.968446601941743 83.88349514563107 0.6644002102675167 0.5345165392282933 7.187939907318809 8.37593753149639 0.9881357365384656 0.3722270618536288 0.235693007183965 0.3229860752418801 0.2065419644469071 0.2435286120595283 0.0086830373469437 +Abnormal lower limb bone morphology 48 193 1.9699239287459809 0.0488470895559025 36.657766990291265 165.25728155339806 0.5352167715889311 0.634339097616788 11.388414435872194 20.95665476687095 0.8935720216867307 0.3771208726436903 0.453695234124389 0.2536237222580642 0.1467252669413004 0.0228215847116225 8.460653641638623e-05 +Generalized hyperkeratosis 3 6 1.969546044861744 0.0488904205279565 1.730582524271845 4.912621359223301 1.0808782092062823 0.2557560852549371 1.1711485734328595 0.780301113356215 1.0121219678622022 0.243080004206366 1.0 1.0 1.0 0.0229613270793894 0.000918782674844 +Flared iliac wing 2 6 1.96948779855132 0.0488971023515638 1.364077669902913 5.334951456310679 0.5405486604626366 0.4179648529865938 0.9746649281279828 1.0213458413978087 0.9547768473806943 0.2811422579068001 1.0 0.0683810764565047 0.1336663515258769 0.0495157384890535 0.0336357980244025 diff --git a/msigdb_hp/metrics.json b/msigdb_hp/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..37aa0af2d42d8b777d6a0a1b7258c15ece0b1f5a --- /dev/null +++ b/msigdb_hp/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 4647, + "title": "Average number of proteins per term", + "value": 25.901656982999786 +} \ No newline at end of file diff --git a/msigdb_hp/paths.json b/msigdb_hp/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..544fd59c520c696bba31fb0fbfbd3e07ddfc72b6 --- /dev/null +++ b/msigdb_hp/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_hp/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/msigdb_hp/result.tsv b/msigdb_hp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c7d2cc2a35bc4cb2c316f476758e53aabb4aa70d --- /dev/null +++ b/msigdb_hp/result.tsv @@ -0,0 +1,2056 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Action tremor 0.5881309208633313 3.3194545108816413 0.0009019349798529 0.9849018509935846 0.0208521982655547 60 Q99720,Q14108,O75027,O14773,Q9NR77,O75787,Q9H6K4,Q9BUB7,P03886,P20700,P07602,Q15233,P00846,Q9Y4W6,Q9Y448,P41440,O75569,O75306,Q01082,O43681,Q9NQH7 21 +Abnormality of peripheral nerves 0.5955434897432718 3.2247614436621457 0.0012607767889791 0.997155949993146 0.0271242117517881 51 Q9NR77,Q99720,P07602,O95831,P02545,Q71SY5,P39210,O43681,Q9GZY8,P07196,Q00796 11 +Abnormal peripheral nervous system physiology 0.5664006523540751 3.036004101587628 0.002397361031472 0.9999856808397344 0.0443846084193248 55 Q9NR77,Q99720,P07602,Q7Z406,O95831,P02545,Q71SY5,P39210,O43681,Q9GZY8,P07196,Q00796 12 +Juvenile onset 0.59524366693262 3.024299153646645 0.002492098809349 0.9999907901538664 0.0459554887581159 46 P35579,Q9NR77,P16278,O15118,P22466,Q03252,P02545,P06753,Q14566,Q8NHS3,P39210,O75027,P54802,P07196,P41440,P06280 16 +Abnormal nerve conduction velocity 0.6052954480598592 3.0229277223806146 0.0025034202730587 0.9999912633173028 0.0459817945015963 44 Q9NR77,Q99720,P07602,O95831,P02545,Q71SY5,O43681,Q9GZY8,P07196,Q00796 10 +Abnormal metatarsal morphology 0.6748872333121573 3.000973677171612 0.0026911782779082 0.9999963572203228 0.0486611107293364 31 Q8WVQ1,Q96L58,Q7RTS9,Q15392,O43505,Q03252,Q9Y448,Q9H9S5,P08236,Q9Y366,Q9UBM7,O96028 12 +Toe walking 0.718184191804798 2.893916096587788 0.0038046981332888 0.9999999797305728 0.0645799155277755 23 Q99720,P07602,Q8TD16,O95831,P02545,Q01082,Q9H9S5,O43681 8 +Abnormal motor nerve conduction velocity 0.7121536435144517 2.8055840610683376 0.0050225478861976 0.9999999999311154 0.0818939650075798 21 Q9NR77,Q99720,Q71SY5,P07196,Q00796 5 +Abnormality of the gallbladder 0.5856700505452305 2.796019913153011 0.005173621260722 0.9999999999659852 0.0840623006943198 42 P22830,P04066,P07602,Q15056,Q15437,Q71SY5,O43681,O00192,Q9UBM7,O96028,Q9UIG0 11 +Platyspondyly 0.6089129959085731 2.7906103436537486 0.0052608764497323 0.999999999977372 0.0851822050937505 36 P16278,O00754,P04066,Q8WVQ1,Q96L58,Q7RTS9,Q14739,O95831,P08236,Q96HY6,P00813,P48735 12 +Sensorimotor neuropathy 0.5891481353228356 2.757459445583457 0.0058252438628378 0.9999999999983809 0.0899332499355737 40 Q9NR77,P03886,O60313,P07602,P00846,Q7LG56,O95831,Q5KU26,P39210,P41440,Q9Y2R0,P07196,P00403 13 +Cone shaped epiphysis 0.7599801000015216 2.7444654140062914 0.0060609540733069 0.999999999999462 0.0932624290684024 16 Q15051,O15078,Q7RTS9,O95831,Q9Y366 5 +Slowly progressive 0.5270039896169042 2.731523251411245 0.0063042292417956 0.9999999999998276 0.0960516501200797 58 Q9NR77,Q99720,Q8IV08,O00584,O75787,O95831,P02545,O43707,O14773,P41440,Q13049,P07196 12 +Parkinsonism 0.6300570793483123 2.6993254929572488 0.006948018401623 0.9999999999999916 0.1051708192584442 31 Q99720,P07602,O75569,O96008,O75787,Q14203,Q9Y4W6,Q96RR1,P05067 9 +Peripheral demyelination 0.7008718102474187 2.695275265163081 0.007033050318038 0.9999999999999944 0.10565584892734 19 Q9NR77,P20700,P03886,P07602,P00846,O43681,P07196 7 +Bulbar signs 0.7942517889025917 2.6945313237335293 0.0070487700889925 0.9999999999999948 0.10565584892734 14 P03886,Q99720,P00846,P07602 4 +Abnormal muscle fiber morphology 0.4916848665596308 2.676117054543415 0.0074480627116897 0.9999999999999992 0.1105787457547035 75 Q99720,P51114,O96008,P02545,P06753,P05067,P13807,O60313,Q70HW3,O43676,Q7Z406,O95831,Q9BPX6,Q96RR1,Q13049,P00403,P03886,P23786,P00846,Q7LG56,Q9H9S5,P07196 22 +Inability to walk 0.4819631626319056 2.64667492150507 0.0081287452703548 1.0 0.1162285516041206 91 Q9NR77,P11166,Q99720,Q96N66,Q7RTS9,P00846,O75787,Q71SY5,Q9H9S5,O75503,Q96RR1,Q96CU9,P07196,Q9GZY8 14 +Abnormal gallbladder morphology 0.5947932792955122 2.637804536315836 0.008344466369385 1.0 0.1182217537150371 34 P22830,O43681,P07602,Q15437 4 +Aplasia hypoplasia involving the vertebral column 0.7170488833102412 2.636260432607297 0.0083825368035175 1.0 0.1184001474952764 17 P16278,P04066,Q7RTS9,O95831,Q14739,Q96HY6 6 +Distal muscle weakness 0.4891110015657612 2.616394253158995 0.0088863885189505 1.0 0.1243149961033835 70 Q9NR77,Q99720,Q7Z406,Q8TD16,P00846,Q14203,O95831,P02545,Q71SY5,P06753,P39210,P41440,P07196,Q00796 14 +Dysphagia 0.4070389806766942 2.5977718077875656 0.0093830826056704 1.0 0.1290035055282561 144 Q05639,Q99720,Q01105,Q14108,O15344,O15118,Q9HD42,Q8IZA0,Q8N3U4,P06753,P05067,Q9NR77,O60313,Q9UHX1,Q8N0X7,P15586,Q14203,Q14739,Q96RR1,P29372,P03886,P20700,P55011,O95155,P07602,Q15233,P00846,Q7LG56,Q9Y4W6,P48735,P17480,P61916,O75569,O75306,Q14331,P42356,Q8NFF5,Q9UEY8,Q9GZY8 39 +Vitamin b12 deficiency 0.9664927217797308 2.571174918572523 0.010135412032775 1.0 0.1361250280818078 2 P41440 1 +Peripheral hypermyelination 0.9659434221367748 2.568926716510809 0.0102014028313983 1.0 0.1366164811455568 2 Q9NR77 1 +Alveolar ridge overgrowth 0.9634715737434764 2.5588031344292124 0.0105033202736466 1.0 0.1394540837475313 2 Q15392 1 +Supranuclear gaze palsy 0.6712809829601898 2.5433185168738404 0.0109805082050193 1.0 0.1437363989541552 20 Q99720,P07602,O15118,P61916,Q14203,Q96RR1,Q969N2 7 +Abnormal femoral neck morphology 0.5488053684700417 2.5355306373984643 0.0112277106746583 1.0 0.1457946542733582 43 P16278,O00754,P55011,P04066,Q8WVQ1,Q96L58,Q9Y487,Q7RTS9,O75718,O95831,P02545,O75431,O75530,O75844,P11274,Q96HY6 16 +Impaired proprioception 0.5254493393084351 2.5251039871555307 0.0115664058786728 1.0 0.1468554320169201 48 Q9NR77,Q5THJ4,P20700,P41440,Q8IV08,Q8N0X7,P00846,Q9Y448,O75298,Q9H6K4,O14773,P54802,Q5TAQ9,Q96RR1,Q9Y619,P07196,Q00796 17 +Clumsiness 0.6730168323747602 2.515118119845394 0.0118992509472619 1.0 0.1494511232858421 18 Q9NR77,P07602,P06753,O14773,O43681,O75503,Q96RR1 7 +Abnormal peripheral myelination 0.5740072276590379 2.507014162559021 0.0121755833110084 1.0 0.1497217772885583 35 Q9NR77,P20700,P03886,P07602,P00846,P02545,Q01082,P39210,O43681,P07196 10 +Dysdiadochokinesis 0.7350266329341061 2.500658640866905 0.0123962599425084 1.0 0.1504515948912783 15 O75503,P41440,O75027,Q6DKK2 4 +Cystathioninemia 0.9489151332051629 2.498965066046719 0.0124556588881103 1.0 0.1507329345131485 2 Q9NUN5 1 +Proximal muscle weakness 0.4888144490265401 2.4969378761998287 0.0125270900753196 1.0 0.1512036041039226 65 Q99720,P51114,Q8TD16,P02545,P06753,Q13126,P10253,Q00796,O60313,Q7Z406,Q9BPX6,Q96RR1,Q13049,P50336,P00846,Q7LG56,Q9H9S5,Q8NAT1,Q8NFF5,P07196 20 +Limb muscle weakness 0.4691153217154517 2.491181346647972 0.0127319116527802 1.0 0.1532777032395585 89 Q9NR77,Q99720,Q8N0X7,P00846,Q7RTS9,Q7Z406,Q14203,Q14739,P02545,P06753,O75298,Q13126,P39210,Q96RR1,Q13049,P07196,P50336,Q00796 18 +Disproportionate short stature 0.628710456824797 2.4853574828098535 0.0129421396944147 1.0 0.1554060029972743 27 O00116,P16278,Q9UHX1,Q8WVQ1,Q7RTS9,Q15392,O75718,Q96HY6,Q9Y366,Q9UBM7 10 +Glomerulopathy 0.796734373626456 2.483875160846591 0.0129961359670585 1.0 0.1556521748425796 11 Q03252,Q14108,P06280,Q9NZ08 4 +Biliary tract abnormality 0.6064933552527294 2.482149344044698 0.0130592529635451 1.0 0.1560060373305767 30 Q14108,P07602,O15078,P14174,O43681,O96028,Q9NUN5 7 +Incoordination 0.4728812522192879 2.480622376534084 0.0131153234890812 1.0 0.1562741237275916 76 Q9NR77,O00754,P07602,Q7RTS9,P00846,O75787,P06753,Q9H9S5,O14773,O43681,O75530,O75503,Q96RR1,Q9NUN5,Q6DKK2 15 +Abnormal femoral neck head morphology 0.507531890430678 2.4612142742916325 0.0138467640691206 1.0 0.1641477362989891 51 P16278,O00754,P55011,P04066,Q8WVQ1,Q96L58,Q9Y487,Q7RTS9,O75718,Q14739,P02545,O95831,O75431,O75530,O75844,P11274,Q96HY6 17 +Abnormality of the peripheral nervous system 0.4503507133372998 2.446171461562078 0.0144382318638431 1.0 0.1690036863256405 108 Q99720,Q71SY5,P02545,P39210,O00192,Q9UBM7,Q96EK5,P06280,Q00796,Q9NR77,Q7Z406,O95831,P42892,Q96RR1,P50336,P20700,P07602,O15078,Q8WXW3,P41440,O43681,P07196,Q9GZY8 23 +Foot dorsiflexor weakness 0.5756555056369788 2.4336213150208263 0.0149486251516552 1.0 0.1741009049617597 33 Q9NR77,Q99720,Q9BQT8,Q7LG56,Q14739,P02545,P06753,P39210,P07196 9 +Ectrodactyly 0.7217240274034981 2.4310854104241635 0.0150536654656581 1.0 0.1744444844907116 15 Q9NR77,Q99720,O96028,P07196 4 +Fingerprint intracellular accumulation of autofluorescent lipopigment storage material 0.932436143916505 2.4307676761788772 0.0150668721364541 1.0 0.1744444844907116 2 O75503 1 +Lower limb amyotrophy 0.6584794476045523 2.4301939978419163 0.0150907430095257 1.0 0.1744444844907116 18 Q9NR77,Q8TD16,P02545,P06753,P07196 5 +Abnormality of the metaphysis 0.4891249805377451 2.4241879202788574 0.0153426639187423 1.0 0.1753926682794265 61 P16278,Q8WVQ1,Q96L58,Q9HC07,Q7RTS9,P48735,Q14739,O95831,Q13126,P51798,O75530,Q9Y366,P00813,Q96HY6 14 +Coxa vara 0.6997886772629933 2.422851333877683 0.0153992271697882 1.0 0.1753926682794265 16 Q8WVQ1,Q9Y487,Q7RTS9,O75718,O95831,Q96HY6 6 +Abnormality of femur morphology 0.4668633545521973 2.4164860236335226 0.0156711278457775 1.0 0.1780531322721958 76 O00116,Q7RTS9,P02545,P06280,P16278,Q9UHX1,Q8WVQ1,Q96L58,Q9Y487,O75718,Q14739,O95831,O00754,P55011,P07602,O75431,P51798,O75530,P11274,P04066,Q96HY6,O75844 22 +Abnormality of the pubic bone 0.8229873304298378 2.404268243366264 0.0162048776348167 1.0 0.1786066809121084 9 O96028,Q7RTS9 2 +Aplasia hypoplasia of the colon 0.9255698983795658 2.4022095480296892 0.0162963702833514 1.0 0.1786066809121084 2 O75844 1 +Prominent umbilicus 0.9255698983795658 2.4022095480296892 0.0162963702833514 1.0 0.1786066809121084 2 O75844 1 +Epidermal hyperkeratosis 0.9255698983795658 2.4022095480296892 0.0162963702833514 1.0 0.1786066809121084 2 O75844 1 +Stiff skin 0.9255698983795658 2.4022095480296892 0.0162963702833514 1.0 0.1786066809121084 2 O75844 1 +Abnormal shoulder physiology 0.9255698983795658 2.4022095480296892 0.0162963702833514 1.0 0.1786066809121084 2 O75844 1 +Shoulder girdle muscle weakness 0.6747692102688783 2.399970693940266 0.0163963844862384 1.0 0.1788905605223429 17 P07602,Q8TD16,Q7LG56,P06753,Q9H9S5,Q96RR1,Q13049 7 +Increased connective tissue 0.8533340750855407 2.399595098713287 0.0164132158113485 1.0 0.1788905605223429 8 P02545,P07196,O75431,O95831 4 +Dysostosis multiplex 0.851871234797619 2.3934145200040957 0.0166923704069839 1.0 0.1808145577651612 8 P16278,O00754,P04066,P15586,P54802,P10619 6 +Progressive gait ataxia 0.7730956111670677 2.3730130053726155 0.0176436426641737 1.0 0.1864760511244655 11 Q96RR1,P00846,P07602,O43681 4 +Visual loss 0.4876517368058872 2.3625383940890603 0.0181502612672996 1.0 0.1898626687512288 58 O14773,O75503,A2RRP1,O60313,Q96JJ3,Q8NHS3,P00403,P03886,P07602,Q15046,P50897,O15078,P00846,P52732,P51798,P04439,Q15051,O75306,Q01082,Q9NWW5 20 +Abnormal pyramidal sign 0.4153977845875432 2.361903316726929 0.0181813831707116 1.0 0.1898626687512288 130 Q99720,O75298,O75027,O14773,Q9NR77,P11166,O60313,Q8N0X7,O75787,O95831,O75251,Q9H6K4,Q969N2,Q6DKK2,P20700,O00754,P07602,Q15046,P00846,Q7LG56,Q9Y4W6,Q9H9S5,P41440,P04066,O75569,Q9NZ08,O75306,O43681,P07196,Q9UEY8 30 +Paresthesia 0.588509190295992 2.3575760159541175 0.0183946887567525 1.0 0.1912306904980515 30 Q9NR77,Q9NZ08,P07196,P06280,P54802,P05067 6 +Dementia 0.4837245377878754 2.3552571525257315 0.0185098913836803 1.0 0.1919988063838446 60 P03886,P20700,O60313,Q14108,P07602,P27544,O15118,P61916,O96008,Q9Y487,P00846,Q7LG56,Q14203,O43681,Q9NWW5,Q96RR1,P05067 17 +Postural instability 0.6862494607077273 2.3488003878242 0.0188340005859608 1.0 0.1944800623982073 16 Q9NR77,O75503 2 +Abnormal sella turcica morphology 0.7789484230598076 2.3479974196068567 0.0188746520640394 1.0 0.1944800623982073 10 P16278,O00754,Q7RTS9,O75431 4 +Extra axial cerebrospinal fluid accumulation 0.9121120571271618 2.345993530026251 0.0189764368745102 1.0 0.1945946297861036 2 Q03252 1 +Heterogeneous 0.5136194528657565 2.345634883694262 0.0189947043700438 1.0 0.1945946297861036 46 Q9NR77,P11717,P03886,Q9Y3D3,Q15555,O15344,Q15051,P61916,P00846,Q9NWH9,Q14203,P02545,P06753,P07196,O75844,P05067,P29372 17 +Ventricular arrhythmia 0.5290241785075261 2.3416491880969423 0.0191987512466562 1.0 0.1960804330620036 42 P03886,P49748,P23786,P00846,O43772,Q7LG56,P02545,P10253,P42892,P09493,Q96RR1,Q8NFF5,P50336 13 +Abnormal pericardium morphology 0.7654642469563323 2.3369112498781472 0.0194437992697671 1.0 0.1972823912808032 11 P02545,Q14108,P14174,Q9NZ08 4 +Fibrous tissue neoplasm 0.6384591195138458 2.328547543151064 0.0198830477954381 1.0 0.1988286456798429 19 Q96JJ3,Q13126,Q15392,Q15437 4 +Kinetic tremor 0.549691910667509 2.323103406357095 0.0201735980382442 1.0 0.1997487981726107 35 P20700,Q14108,P07602,Q15233,Q9Y4W6,Q01082,Q9Y448,O75027,O43681,Q9BUB7,Q9NQH7,P41440 12 +Babinski sign 0.4528151126875567 2.320003571743724 0.0203406841204802 1.0 0.1997487981726107 91 Q9NR77,P11166,Q99720,P20700,P07602,Q8N0X7,P00846,Q969N2,O75787,O95831,O75298,O75027,O43681,O14773,P41440,P07196,Q6DKK2 17 +Abnormality of the ribs 0.4581293637494057 2.318804030462296 0.0204056645675847 1.0 0.1997487981726107 71 Q7RTS9,P02545,P54802,Q9UBM7,P16278,Q9UHX1,Q96L58,P15586,O75718,Q14739,O95831,P00813,O00754,O95155,O75431,O96028,Q96HY6,O60826,O75844 19 +Limb girdle muscle weakness 0.5967217627718557 2.31778806641995 0.0204608419862537 1.0 0.1997487981726107 28 P07602,Q8TD16,Q7LG56,Q14331,P02545,P06753,Q9H9S5,Q13126,Q96RR1,Q13049 10 +Hypertriglyceridemia 0.6288480564732971 2.3078722797450397 0.0210062412605409 1.0 0.1997487981726107 21 P22830,P28070,P02545,O75431,Q969N2 5 +Periventricular white matter hyperintensities 0.8284038524175813 2.2936499340071936 0.0218106147075256 1.0 0.2039650096309334 8 O75503,P07602 2 +Muscle stiffness 0.6212993015048142 2.282029852542516 0.0224875778450048 1.0 0.2057897544644785 22 P11166,P07602,P23786,P00846,P53985,Q15392,P52732,P06753 8 +Abnormal biliary tract morphology 0.6028147457180346 2.2736693864256803 0.0229858721427238 1.0 0.2077573272661749 26 Q14108,P07602,O15078,P14174,O43681,Q9NUN5 6 +Abnormal circulating lipid concentration 0.452591041729767 2.268173533011974 0.0233186319409635 1.0 0.2095970650476932 79 P22830,O43772,P02545,Q9UBM7,P06280,P49748,P28070,Q15392,Q14739,Q969N2,P07602,Q15056,P23786,Q03252,O43707,O75431,P61916,P31751,O75844,Q9NUN5,Q9UIG0 21 +Amyotrophic lateral sclerosis 0.688038462706402 2.252353073414687 0.0242999687058911 1.0 0.2125919594228555 15 Q99720,Q15165 2 +Joint contracture of the hand 0.4770733137008161 2.247507388913387 0.0246076188966879 1.0 0.2130762001970689 57 Q9NR77,O95155,Q8WVQ1,Q8IZA0,Q15392,P02545,Q71SY5,P06753,P42892,O75530,O75844,P11274,P07196 13 +Demyelinating peripheral neuropathy 0.6211020256478148 2.2411313802620456 0.0250175660728813 1.0 0.2156206130294063 20 Q9NR77,P00846,P03886,P41440 4 +Phalangeal dislocation 0.8846470749794006 2.23028176390657 0.0257287430554236 1.0 0.2197821120929292 2 Q96L58 1 +Advanced ossification of carpal bones 0.8846470749794006 2.23028176390657 0.0257287430554236 1.0 0.2197821120929292 2 Q96L58 1 +Postural tremor 0.6160037721899126 2.2285650280589806 0.0258428601194995 1.0 0.2199688150222581 21 Q9NR77,P03886,P20700,Q14108,O75569,P00846,O75306,O14773 8 +Knee clonus 0.8840977753364467 2.227954188571329 0.0258835700676263 1.0 0.2199688150222581 2 O75298 1 +Muscle hypertrophy of the lower extremities 0.7531739637723833 2.227818714426752 0.0258926063733968 1.0 0.2199688150222581 10 Q9NR77,P02545,Q9H9S5,Q14331 4 +Abnormality of the shoulder girdle musculature 0.5284476878938853 2.2269735552696504 0.0259490412279244 1.0 0.2200459755221984 38 P07602,Q9Y487,Q8TD16,Q7LG56,Q14331,P02545,P06753,Q9H9S5,Q96RR1,Q13049,P07196 11 +Asymmetric septal hypertrophy 0.8824498764075781 2.2209683544657297 0.0263531048500347 1.0 0.2230653519819879 2 P54802 1 +Suicidal ideation 0.8821752265861029 2.2198035959425524 0.0264321027285876 1.0 0.223107314177939 2 Q01082 1 +Giant platelets 0.8819005767646242 2.2186387081461976 0.0265113139249983 1.0 0.223107314177939 2 P35579 1 +Positive romberg sign 0.7404813346284282 2.217657367160845 0.0265782031862544 1.0 0.223107314177939 11 Q96RR1,P41440,P07196,Q8IV08 4 +Premature rupture of membranes 0.8849712510597199 2.217365613725116 0.0265981175069029 1.0 0.223107314177939 6 Q9Y487,O75844 2 +Distal lower limb amyotrophy 0.6982325297911567 2.2084075353964865 0.0272158769874999 1.0 0.2268040855172547 14 Q9NR77,P02545,Q8TD16,P07196 4 +Impaired pain sensation 0.6127148801552342 2.208146525807302 0.0272340606237633 1.0 0.2268040855172547 21 Q9NR77,Q13045,O15269,O95714,O95831,O95140,P39210,P07196,P17480,Q14683,Q00796 11 +Abnormality of the calf 0.447254761354308 2.202723097386225 0.0276142712859279 1.0 0.2295590673805139 71 Q7RTS9,Q13126,Q9NR77,P16278,Q8WVQ1,Q8N0X7,Q96L58,O75718,O95831,O00754,Q15056,P08236,O75431,P51798,Q9NX62,Q9NWH9,Q01082,Q96HY6,Q9NUQ7,Q9UIG0 20 +Hammertoe 0.6172575103568944 2.2003854228603026 0.0277795611798246 1.0 0.2298566337432459 19 Q9NR77,Q99720,P07196,P39210 4 +Beaking of vertebral bodies 0.7772129697787282 2.2003614519766517 0.0277812604977123 1.0 0.2298566337432459 9 P16278,Q96L58,Q7RTS9,P04066 4 +Vascular skin abnormality 0.3959299982688786 2.2001189507277132 0.0277984566739195 1.0 0.2298566337432459 135 P22830,Q14108,Q8IZA0,Q8WVM7,P02545,Q13126,O00192,Q9UBM7,P06280,P16278,P35579,Q8NCH0,Q96L58,Q9Y487,Q96JJ3,Q14739,Q969N2,P10619,P03886,O95155,P00846,P51798,P78536,Q9UQE7,P04066,O75306,Q15437,Q14331,O75844 29 +Abnormality of extrapyramidal motor function 0.4461268322412414 2.1993777086988984 0.0278510763213213 1.0 0.2298826850180821 80 Q99720,P98175,O96008,P06753,P05067,P16278,P11166,O75787,Q14203,O75251,Q9H6K4,Q9BPX6,Q96RR1,Q6DKK2,P07602,Q15056,Q7LG56,Q9Y4W6,O75569,Q9NWW5,Q9UIG0 21 +Gait ataxia 0.446568704436202 2.1986573387380854 0.0279022965533082 1.0 0.2298971136227363 77 Q14108,O15118,O14773,Q9P0J1,Q9NR77,Q5THJ4,Q96RR1,Q5H8A4,P03886,P20700,O00754,P07602,Q8IV08,P00846,Q7LG56,Q03252,Q9Y4W6,P41440,P17480,O43681,P07196 21 +Abnormal enchondral ossification 0.5655436399158801 2.196065086322696 0.0280872851170053 1.0 0.2310117060862366 30 O00116,Q8WVQ1,Q96L58,Q7RTS9,Q14739,P08236,Q96HY6,O96028,Q9UBM7 9 +Disproportionate short limb short stature 0.6066014532574966 2.189929446295508 0.0285293540350264 1.0 0.2337285335635005 22 O00116,Q8WVQ1,Q7RTS9,Q15392,O75718,Q9Y366,Q9UBM7 7 +Aplasia hypoplasia of metatarsal bones 0.7346091799213736 2.1893901175657033 0.0285684973238795 1.0 0.2337285335635005 11 Q9Y366,Q9Y448,Q7RTS9 3 +Abnormality of the odontoid process 0.8037418550513105 2.187563431334538 0.0287014180198874 1.0 0.234268612452505 8 Q7RTS9,O95831 2 +Splenomegaly 0.4367997071827492 2.1830881080887146 0.0290293221567918 1.0 0.2346507935209117 98 Q14108,O15118,P14174,P02545,P10253,P54802,O00192,P16278,P11166,P28070,Q15392,P15586,Q14739,P00813,O14936,O00754,P07602,P08236,P11274,P04066,P61916,Q9NZ08,Q15437,Q96HY6 24 +Abnormal acetabulum morphology 0.5981178470339404 2.180259029435273 0.029238266202936 1.0 0.2354769896794517 24 P16278,Q8WVQ1,Q96L58,Q7RTS9,O75718,P08236,Q9Y366 7 +Abnormal csf protein level 0.6555943207340216 2.178790506627709 0.0293472345186915 1.0 0.2359456726788232 16 P03886,P20700,Q9NR77,P55011,P07602,Q7LG56,O43681,Q16625,P00403 9 +Respiratory arrest 0.8013904040434635 2.1773821157688795 0.0294520689293611 1.0 0.235972007439209 8 P23786,Q96L58,O43772,P49748 4 +Neck muscle weakness 0.6157125631556217 2.175462005874245 0.0295955123144209 1.0 0.2360087885905516 18 Q99720,P07602,P02545,P06753,Q13049 5 +Hypothermia 0.7175033401063667 2.158833332842774 0.0308630994768808 1.0 0.2421381302254975 12 P03886,P20700,P00846,O43772 4 +Hypoplasia of the odontoid process 0.8227311796744996 2.1535678377481293 0.0312740787719234 1.0 0.2444515470754979 7 Q7RTS9,O95831 2 +Clonus 0.5192079154867228 2.1532443836427366 0.0312994771917196 1.0 0.2444515470754979 38 P20700,Q99720,P07602,O75787,Q01082,O75298,Q9H9S5,O75027,Q969N2 9 +Increased cerebral lipofuscin 0.8668409919908192 2.145028960086657 0.0319505315868209 1.0 0.2482844820801954 6 O75503,Q9NWW5,P07602,P50897 4 +Abnormality of tibia morphology 0.6484621191330588 2.138770161372847 0.0324542871647433 1.0 0.2513584540909368 16 Q7RTS9 1 +Rhizomelia 0.7020524363291352 2.137767690750422 0.0325356025021938 1.0 0.2515689597798586 13 O00116,Q7RTS9,Q15392,O75718,Q9Y366,Q9UBM7 6 +Abnormal epiphysis morphology of the phalanges of the hand 0.7625227524171256 2.133907204051206 0.032850377660456 1.0 0.2535809052959125 9 Q7RTS9 1 +Short nail 0.8617779389189624 2.1247278385373325 0.0336093291536219 1.0 0.2589781138352432 6 P02545,Q9Y487,O75844 3 +Difficulty walking 0.4377553955950737 2.1241090673545298 0.0336610244795538 1.0 0.2589781138352432 86 Q9NR77,Q99720,P07602,P00846,Q7RTS9,Q8TD16,Q71SY5,Q96F07,P06753,Q9H9S5,O75298,O14773,O43681,Q9BPX6,Q00796 15 +Corticospinal tract hypoplasia 0.8593792914034613 2.1226823343552312 0.0337804803224313 1.0 0.2594675901790715 2 P11177 1 +Abnormal vascular physiology 0.4649642188410736 2.118728670074335 0.0341134039461954 1.0 0.2615923896666175 56 Q14108,Q8IZA0,P02545,Q71SY5,P42224,P06280,P05067,Q14739,O14678,O96000,P00403,P03886,P20674,Q15056,Q9NWM8,P51798,P04062,P35222,P31749,Q9NZ08,P25705,O75844,Q9UIG0 23 +Finger agnosia 0.8571820928316358 2.1132752089501894 0.0345772193364675 1.0 0.2631774129958796 2 P05067 1 +Deposits immunoreactive to beta amyloid protein 0.8571820928316358 2.1132752089501894 0.0345772193364675 1.0 0.2631774129958796 2 P05067 1 +Polyneuropathy 0.5992846681385237 2.1065071962282653 0.0351603186801681 1.0 0.265243507965489 20 P03886,P04066,P07602,P00846,O95831,Q01082,Q9HC21 7 +Frequent falls 0.4857952363048231 2.1031793152445637 0.0354500977208487 1.0 0.2660876360114536 46 Q9NR77,P07602,Q7RTS9,P00846,O75787,P06753,Q9H9S5,O43681,Q96RR1 9 +Abnormal rib cage morphology 0.4358886496416473 2.0959490092814734 0.0360867144975791 1.0 0.2696060486659973 84 Q7RTS9,P02545,P54802,Q9UBM7,P16278,Q9UHX1,Q8WVQ1,Q96L58,P15586,O75718,O95831,Q14739,P00813,O00754,O95155,P08236,O75431,O96028,P04066,Q96HY6,O60826,O75844 22 +Proportionate short stature 0.514754448052696 2.094555974906338 0.036210482277738 1.0 0.2700964865885211 37 P16278,Q8WVQ1,Q96L58,Q13555,Q7RTS9,Q15392,P52732,Q96HY6,P10619 9 +Abnormal epiphyseal ossification 0.6210421462616068 2.090155947011746 0.0366037933369844 1.0 0.2717217693881261 17 O00116,Q96L58,Q7RTS9,Q14739,Q96HY6,Q9UBM7 6 +Hyperlipidemia 0.5503334303414594 2.0876018541621044 0.0368337646146541 1.0 0.2725581276501558 30 P22830,P23786,P28070,O75844,O43707,P02545,O75431,Q969N2,P06280 9 +Monochromacy 0.8505904971161751 2.0850061005354763 0.0370687467787922 1.0 0.2738608366948291 2 Q6P4Q7 1 +Contractures of the joints of the upper limbs 0.4352171973618524 2.0827027078307045 0.0372783304828101 1.0 0.274120171177495 82 Q9NR77,Q99720,O95155,Q8WVQ1,P23786,Q96L58,Q8IZA0,Q15392,Q71SY5,P02545,P06753,P42892,O75530,O75844,P11274,P07196 16 +Segmental peripheral demyelination remyelination 0.805880818274407 2.0826754662974727 0.0372808151891923 1.0 0.274120171177495 7 P03886,Q9NR77,P00846 3 +Metatarsus adductus 0.6561855109710412 2.0799706475419173 0.0375282252227002 1.0 0.2755034164453209 15 Q96L58,Q15392,Q03252,O96028,Q9UBM7 5 +Microcytic anemia 0.7211823470547143 2.076335434422485 0.0378629382272803 1.0 0.2766494873304589 10 P22830 1 +Cone shaped epiphyses of the phalanges of the hand 0.7767748179946635 2.07011514377205 0.0384415630702816 1.0 0.279441658797808 8 Q7RTS9 1 +Aplasia hypoplasia involving the pelvis 0.6174736568868993 2.0692000361874725 0.0385273193339592 1.0 0.279441658797808 17 Q8WVQ1,Q96L58,O95831,O75431,Q96HY6,O96028 6 +Loss of subcutaneous adipose tissue in limbs 0.92607859302006 2.0688824613102352 0.0385571177858139 1.0 0.279441658797808 4 O75844,O75431,Q03252 3 +Cognitive impairment 0.3899223088485514 2.068733897004543 0.0385710644856414 1.0 0.279441658797808 185 Q99720,Q14108,P27544,O15118,O96008,P54802,O75503,P05067,P06280,P16278,P11166,O60313,Q8N0X7,Q9Y487,Q14203,O95831,Q8NHS3,Q9H6K4,Q6PGP7,Q96RR1,Q6DKK2,P00403,P03886,P20700,P07602,Q15046,P50897,P00846,Q7LG56,Q9Y4W6,Q96F07,Q9H9S5,Q9Y2R0,P17480,Q9UQE7,P61916,O75569,Q9NZ08,O75306,Q15437,Q01082,O43681,Q9NWW5,P07196,Q9UEY8 45 +Metaphyseal striations 0.8863378960116925 2.0624867704274163 0.0391614158092332 1.0 0.282775518054809 5 Q13126 1 +Disproportionate short trunk short stature 0.8460943092914646 2.061566535061201 0.0392490228416939 1.0 0.282775518054809 6 P16278,Q7RTS9 2 +Ovarian cyst 0.5967407513992543 2.06011948563364 0.0393871194994777 1.0 0.2833311831487196 18 P20585,Q15056,Q15437,Q03252,P02545,P31751,Q9UIG0 7 +Abnormal head movements 0.686557131632395 2.058685659314753 0.0395243608892503 1.0 0.283878987716146 13 P20700,Q99720,Q969N2,P11166 4 +Hemolytic anemia 0.5142710012173646 2.0488619342626677 0.040475617487379 1.0 0.2873995334618785 35 P22830,P00390,P00813 3 +Short thorax 0.7718690893613928 2.0485890020253827 0.0405023209751411 1.0 0.2873995334618785 8 Q9Y366,Q7RTS9 2 +Hypoplastic iliac wing 0.944259868273593 2.048093271125024 0.0405508611214304 1.0 0.2873995334618785 3 Q7RTS9 1 +Lumbar hyperlordosis 0.590938268262977 2.038755164017936 0.041474469144578 1.0 0.2922456982508828 19 Q9H9S5,Q7RTS9,P04066,Q96HY6 4 +Abnormal ovarian morphology 0.5128820680737547 2.037957368150425 0.0415541965478436 1.0 0.2922456982508828 35 P20585,Q15056,O15078,P51809,Q15437,Q03252,P02545,P31751,Q96RK4,Q13049,Q9UIG0 11 +Limb ataxia 0.5671806771303669 2.0366420228381177 0.04168592838966 1.0 0.2922456982508828 26 P31040,Q9NR77,Q5THJ4,Q14108,O00754,Q8IV08,Q10713,Q9Y4W6,O75298,O14773,P04062,P41440,P07196 13 +Ventricular hypertrophy 0.478104786073765 2.035176642982403 0.0418331023510392 1.0 0.2922456982508828 46 P03886,P23786,O43772,O75787,P00403,P02545,Q7LG56,Q9H9S5,P10253,O75431,P78536,Q96RR1,O75844,P06280,P13807 15 +Abnormal social behavior 0.4318112234471032 2.0351509201419624 0.041835689721694 1.0 0.2922456982508828 72 Q9UIG0,Q96N67,Q5KU26,P05067,P11166,Q9UHX1,O43676,O75251,Q96RR1,P03886,P07602,Q15056,Q96CU9,Q9Y3C6,O75306,Q01082,O43681,O75380,Q9GZY8 19 +Abnormal exteroceptive sensation 0.451103646632931 2.0343627460519693 0.0419150350868842 1.0 0.2922456982508828 60 Q9NR77,P07602,Q9NZ08,O95831,P39210,P54802,P06280,P07196,P05067,Q00796 10 +Pericarditis 0.8392142777933042 2.033729088512833 0.041978917618441 1.0 0.2922456982508828 6 P14174 1 +Deep palmar crease 0.6918591029634396 2.0309945523894664 0.0422555472194905 1.0 0.2922456982508828 12 Q9Y487,P98175 2 +Abnormal lung lobation 0.6470130449013842 2.029728283841065 0.0423841662541903 1.0 0.2922456982508828 15 O60566,Q9UHX1,Q14739,O00192,Q9UBM7,Q969N2 6 +Bowing of the legs 0.4491944634193071 2.029697858432604 0.0423872607318904 1.0 0.2922456982508828 61 Q9NR77,P16278,O00754,Q8WVQ1,Q15056,Q8N0X7,Q96L58,Q9NX62,Q7RTS9,O75718,Q01082,P08236,Q13126,O75431,P51798,Q96HY6,Q9NUQ7,Q9UIG0 18 +Slurred speech 0.711179867961172 2.0284520863836195 0.0425141287049446 1.0 0.2926861571731523 10 P16278,Q9Y487,O75787 3 +Vascular tortuosity 0.9149438252423036 2.026501831106119 0.0427133852739403 1.0 0.292756786678467 4 P03886,P05067 2 +Prominent sternum 0.9145238911826724 2.0249001827053346 0.0428776148532508 1.0 0.2931520226414949 4 Q7RTS9,O95831 2 +Decerebrate rigidity 0.9143333890236952 2.024173519494399 0.0429523011847132 1.0 0.2931520226414949 4 P07602,O43681 2 +Angiokeratoma 0.937912087912088 2.0240802158345415 0.0429618988819078 1.0 0.2931520226414949 3 P16278,P06280 2 +Abnormal circulating dicarboxylic acid concentration 0.4801933633809269 2.020924955157642 0.0432875341580361 1.0 0.2931520226414949 45 P22695,P11166,P55263,P41440,P23786,Q14739,O14678,Q01082,P00390,P48735,Q9NUN5 11 +Psychomotor deterioration 0.737486390599112 2.0195280361143597 0.0434323663475075 1.0 0.2932661089782564 9 Q9Y487,P07602 2 +Waddling gait 0.5408042119304564 2.0190512660934363 0.0434818913462489 1.0 0.2932661089782564 30 Q8WVQ1,Q4J6C6,Q7RTS9,Q8TD16,P02545,P06753,Q9H9S5,Q13049,P07196 9 +Muscle fiber atrophy 0.5796045691013023 2.0183783873301104 0.0435518685199822 1.0 0.2933123666845763 22 P02545,Q99720,P23786 3 +Progeroid facial appearance 0.7648510006687621 2.0177091064512505 0.0436215658662462 1.0 0.2933566086547701 8 O75844,O75431,Q03252 3 +Abnormal circulating bilirubin concentration 0.5465425456249023 2.014837644020873 0.0439216633222425 1.0 0.2942485092003201 29 P11166,P55263,P23786,Q14739,Q01082,P00390,P41440 7 +Hyporeflexia 0.3875309690565162 2.014623148925593 0.0439441500720942 1.0 0.2942485092003201 132 Q13045,Q99720,Q8TD16,Q71SY5,P02545,P06753,P39210,P54802,Q9HC21,Q9NR77,Q7Z406,O75787,O95831,Q96RR1,Q5H8A4,Q13049,P50336,P03886,P07602,Q15046,P00846,O43505,Q7LG56,Q96F07,P11177,Q9H9S5,P41440,Q9NWS8,Q8NAT1,Q5TAQ9,O43681,P23378,P07196 33 +Hemihypertrophy 0.8338368580060412 2.012838639472091 0.0441316075126758 1.0 0.2946545691255814 2 P31751 1 +Deformed sella turcica 0.7888939699311638 2.0106654693989023 0.0443608036946012 1.0 0.2957576849171351 7 Q7RTS9,O75431 2 +Short long bone 0.4892967421987419 2.0100668374763004 0.0444241153587605 1.0 0.2957576849171351 42 O00116,P16278,Q9UHX1,P98175,Q96L58,Q7RTS9,Q9NWH9,Q9Y448,Q96HY6,Q9Y366,Q969N2 11 +Hepatic failure 0.4548134197096559 1.999769606377478 0.0455251479775484 1.0 0.3022219466452396 54 P22830,P03886,O15118,P23786,P00846,O43772 6 +Abnormal femoral head morphology 0.5792578290797784 1.9978787842814745 0.0457298032562791 1.0 0.3030814922862074 21 P16278,Q8WVQ1,Q96L58,Q7RTS9,O95831,O75431 6 +Scotoma 0.6235066810847094 1.9973694196014125 0.0457850672659603 1.0 0.3030814922862074 16 P03886,O60313,O43395,P00846,O75306,Q8NHS3,Q9H6K4,P04439 8 +Aplasia hypoplasia of the uterus 0.6047422411110954 1.9940565193907496 0.046145878225877 1.0 0.305035414104766 17 O96028 1 +Abnormal circulating sulfur amino acid concentration 0.703666332903943 1.992322881598856 0.0463356426971297 1.0 0.3058547324056277 10 Q9NUN5,P41440,P55263 3 +Motor deterioration 0.8285812502559435 1.9905526090012633 0.0465300947682219 1.0 0.3064928111150358 6 O75503 1 +Metaphyseal widening 0.5689560817204933 1.9902425899382663 0.0465642187749548 1.0 0.3064928111150358 24 P16278,Q8WVQ1,Q96L58,Q7RTS9,O95831,O75530,Q96HY6 7 +Abnormal pupil morphology 0.6730865142979998 1.9893912456857288 0.0466580351699406 1.0 0.3066759397945034 13 Q9NR77 1 +Short clavicles 0.7292249896124627 1.9814798020093525 0.0475374922539129 1.0 0.3106929886177903 9 O75844,O75431 2 +Adrenal hypoplasia 0.7566055299969816 1.9813021979330308 0.0475573940560318 1.0 0.3106929886177903 8 O60826,O75844 2 +Hyperintensity of cerebral white matter on mri 0.5761032589274618 1.9778160307538992 0.0479494643574121 1.0 0.3117205591666832 21 O75503,P10253,P07602,O43681 4 +Abnormal bone structure 0.3878844430248081 1.977507881256764 0.0479842505414755 1.0 0.3117205591666832 195 O00116,Q86XL3,Q14108,Q9HC07,Q7RTS9,P02545,Q13126,P54802,Q9Y366,Q9HC21,Q9UBM7,P06280,P16278,O60566,Q8WVQ1,Q96L58,Q9Y487,Q96JJ3,Q15392,O75718,O95831,Q14739,Q96RR1,Q969N2,Q5H8A4,O00754,P07602,O15078,Q15056,Q7LG56,Q9Y448,P08236,O75431,P51798,O75530,O15287,O96028,P48735,P31749,Q15051,P51809,P35606,Q15437,Q96HY6,Q9NUQ7,O75844,Q9UIG0 47 +Abnormality of the upper respiratory tract 0.4105860868320822 1.9771095453299772 0.0480292490560243 1.0 0.3117205591666832 110 O15344,Q7RTS9,P02545,P54802,O00192,Q9UBM7,P16278,Q9UHX1,P28070,P15586,Q14203,Q14739,P00813,P29372,O00754,P07602,P08236,P04066,Q68CQ7,Q15165,Q01082,Q96HY6 22 +Ulnar claw 0.9244505494505496 1.97298730319271 0.0484970089253655 1.0 0.3122200211831344 3 Q9NR77,P07196 2 +Abnormality of epiphysis morphology 0.4372407322536623 1.972089347393312 0.0485994078148876 1.0 0.3122200211831344 65 O00116,P16278,Q15051,Q8WVQ1,O15078,Q96L58,Q9HC07,Q7RTS9,Q9NUQ7,Q14739,O95831,Q9Y448,P08236,P51798,Q96HY6,Q9Y366,Q9UBM7,O96028 18 +Abnormal form of the vertebral bodies 0.421138457545958 1.9702054277668084 0.0488148317451506 1.0 0.3122200211831344 94 Q13045,Q7RTS9,Q8N3U4,P54802,Q9UBM7,Q9Y619,P16278,Q9UHX1,Q8WVQ1,Q96L58,P15586,O95831,Q14739,P00813,Q5H8A4,O00754,Q15056,Q8WXW3,P08236,P51798,O96028,P48735,P31749,O15228,P04066,Q9NUQ7,Q96HY6,O60826,Q9UIG0 29 +Abnormal lower limb bone morphology 0.3866422280054329 1.9699239287459809 0.0488470895559025 1.0 0.3122200211831344 193 O00116,P98175,Q7RTS9,Q71SY5,P02545,Q8N3R9,Q9Y366,Q9UBM7,O00192,P06280,P16278,Q9UHX1,Q8WVQ1,Q8N0X7,Q96L58,Q9Y487,Q15392,O75787,O95831,O75718,Q14739,P00813,O14936,O00754,P55011,O95155,P07602,O15078,Q8WXW3,O43505,Q03252,Q9Y448,Q9H9S5,P08236,O75431,P51798,O75530,O96028,P11274,Q9UQE7,P04066,Q9NX62,Q13555,Q9NWH9,Q8NAT1,Q93009,Q96HY6,O75844 48 +Generalized hyperkeratosis 0.8234243822738831 1.9695460448617437 0.0488904205279565 1.0 0.3122200211831344 6 O75844,P04066,Q15437 3 +Flared iliac wing 0.8234100981823868 1.9694877985513195 0.0488971023515638 1.0 0.3122200211831344 6 P16278,O95831 2 +Bilateral tonic clonic seizure with focal onset 0.8982443495660541 1.9626264287675323 0.0496895974800422 1.0 0.3158790143498715 4 P22466 1 +Short middle phalanx of finger 0.8217522658610235 1.960508798847386 0.0499363505717043 1.0 0.3165814749068348 2 Q9UHX1 1 +Arthritis 0.4538785332584523 1.9582434170430176 0.0502014567660313 1.0 0.3165825930330358 50 Q14108,Q8WVQ1,P28070,Q7Z406,Q9NZ08,P14174,P02545,Q14739,Q9Y448,P51798,Q96HY6,O00192,Q9NUQ7,O75844,P06280 15 +Abnormality of the spleen 0.3820783178835641 1.957378438535837 0.0503029915643822 1.0 0.3165825930330358 133 Q14108,O15118,P14174,P02545,P10253,P54802,O00192,P16278,P11166,P28070,Q15392,P15586,Q14739,P00813,P10619,O14936,O00754,O95155,P07602,O15078,P08236,O96028,P11274,P04066,P61916,Q9NZ08,Q15437,Q96HY6 28 +Median cleft palate 0.8209283163965936 1.956932694432007 0.0503553820364595 1.0 0.3165825930330358 2 Q14739 1 +Pathologic fracture 0.5984641237386621 1.9567861016796433 0.0503726217844613 1.0 0.3165825930330358 17 Q14108,Q13126 2 +Abnormal vertebral morphology 0.397616373670936 1.955360402695619 0.050540546388015 1.0 0.3165825930330358 121 Q13045,Q14108,Q8IWS0,Q7RTS9,Q8N3U4,P54802,Q9UBM7,Q9Y619,P16278,Q9UHX1,Q8NCH0,Q8WVQ1,Q96L58,P15586,O75718,O95831,Q10713,Q14739,P00813,Q5H8A4,P10619,Q96L73,O00754,Q15056,Q8WXW3,P34059,Q9H9S5,P08236,P51798,O96028,P48735,P31749,O15228,P04066,Q9NUQ7,Q96HY6,O60826,Q9UIG0 38 +Hyperhomocystinemia 0.8587664261683288 1.9541638973097384 0.0506818374020596 1.0 0.3165825930330358 5 P41440,Q9NUN5 2 +Pleural effusion 0.6763793548222875 1.952978288366258 0.0508221679368721 1.0 0.3165825930330358 12 Q9NZ08,P52732,P14174 3 +Aplasia hypoplasia of the femur 0.6155760257683066 1.9519927960538288 0.0509390599087233 1.0 0.3168859590305724 16 O00116,Q9UHX1,Q96L58,O95831,O75431,Q96HY6 6 +Osteoarthritis 0.6760298460417006 1.951209549787014 0.0510321234327124 1.0 0.3170404780639235 12 Q14108,Q8WVQ1,P02545,P51798,Q96HY6,O75844 6 +Abnormality of the musculature of the upper limbs 0.4241240511234068 1.950100756080523 0.0511641111649494 1.0 0.3172583229394285 76 Q9NR77,O60313,P07602,Q9Y487,Q8TD16,Q7LG56,Q14203,P46783,P02545,Q14331,P06753,Q9H9S5,Q96RR1,Q13049,P07196,P50336 16 +Aplasia hypoplasia involving the skeletal musculature 0.6851127649703896 1.9475854883099737 0.0514645815430461 1.0 0.3176739720193887 11 Q9NR77,Q9Y487,O43505,P06753,Q9H9S5 5 +Abnormality of the calf musculature 0.576272451123171 1.947490992301378 0.0514758986293522 1.0 0.3176739720193887 19 Q9NR77,Q14331,P02545,Q9H9S5,Q13049 5 +Distal lower limb muscle weakness 0.576079739644897 1.9462861493990145 0.0516203764099763 1.0 0.317948786796964 19 Q9NR77,P00846,P02545,P07196,Q00796 5 +Abnormal iliac wing morphology 0.6314818000683061 1.9440517357893663 0.051889212597123 1.0 0.3181123627161359 15 P16278,Q7RTS9,O75530,O95831 4 +Abnormality of bone mineral density 0.3674137019810518 1.9416514107213976 0.0521793146152484 1.0 0.3190922743278276 152 Q14108,Q9HC07,P02545,Q13126,P54802,Q9Y366,P06280,P16278,Q8WVQ1,Q96L58,Q9Y487,Q15392,O75718,O95831,Q14739,Q96RR1,Q969N2,O00754,P07602,O15078,Q15056,Q7LG56,Q9Y448,O75431,P51798,O75530,O96028,Q15051,P51809,Q96HY6,Q9NUQ7,O75844 32 +Young adult onset 0.6838112019122063 1.941143039919152 0.0522409297904531 1.0 0.3190922743278276 11 P02545,P07602,O15118 3 +Head tremor 0.6307308137647204 1.9398899755588372 0.0523930626155282 1.0 0.3195151731946977 15 P20700,Q99720,P07196 3 +Abnormality of lower limb epiphysis morphology 0.5770094150676917 1.9386569185504687 0.0525431278068693 1.0 0.3199909494098208 18 Q96L58,Q7RTS9,Q8WVQ1,O95831 4 +Severe short stature 0.5472587409302481 1.9381182431923645 0.052608798224468 1.0 0.3199909494098208 27 P16278,Q96L58,Q7RTS9,Q15392,P52732,Q96HY6,P10619 7 +Abnormality of the achilles tendon 0.6469576940394088 1.937431345260341 0.0526926381083494 1.0 0.32008194678366 14 O60313,Q8N2K0,P50402,Q8WXH0,Q8TD16,P02545,Q9H9S5,Q92734 8 +Titubation 0.7191697986074854 1.9349691525940216 0.0529940811854827 1.0 0.3207457755966617 9 P20700,Q99720 2 +Decreased adenosylcobalamin 0.913942516565584 1.932947987861932 0.0532426054444479 1.0 0.3217404258782178 3 Q9NUN5 1 +Hyperventilation 0.7178500392507724 1.92884834208043 0.0537496924261793 1.0 0.3233774411110041 9 P03886,P11166,P00846 3 +Morphological abnormality of the pyramidal tract 0.5561039064380053 1.9273234478818344 0.0539393331984077 1.0 0.3233774411110041 25 Q13045,P11166,O00400,Q15056,O75569,P35637,P00846,Q14203,O95831,P11177,O75298,Q9Y619,Q9UIG0 13 +Pace of progression 0.3771280946103084 1.9272834640787329 0.0539443132178318 1.0 0.3233774411110041 176 Q99720,P07942,P55263,Q14108,P02545,O75298,Q13126,P39210,P54802,O14773,Q9NR77,Q7Z406,O75787,P15586,O95831,O75251,Q14203,Q8NHS3,Q96RR1,Q13049,P20700,Q8IV08,Q7LG56,Q03252,O43707,Q8N1F7,P41440,O00584,O75569,P35606,P07196,Q9GZY8 32 +Nasogastric tube feeding in infancy 0.7169904824424868 1.924859860726482 0.054246892697733 1.0 0.3233774411110041 9 Q969N2,Q9UHX1,P07602 3 +Goiter 0.6804775190272929 1.924622904108581 0.0542765518583647 1.0 0.3233774411110041 11 Q96RR1,P48735,Q7LG56,Q15437 4 +Vegetative state 0.9111338431219884 1.9222232295769597 0.0545776750764392 1.0 0.3233774411110041 3 P07602 1 +Progressive peripheral neuropathy 0.9111338431219884 1.9222232295769597 0.0545776750764392 1.0 0.3233774411110041 3 P07602 1 +Wormian bones 0.5739470487507795 1.9196706447587095 0.0548995144524835 1.0 0.3233774411110041 18 P02545,Q9Y487,O75844,O95831 4 +Increased serum pyruvate 0.490178290638957 1.918180904508562 0.0550880766449717 1.0 0.3233774411110041 38 P03886,Q70HW3,O43676,O75251,O95831,Q9BWD1,O75380,Q96RR1,Q96CU9 9 +Childhood onset 0.4843549437274762 1.9163664965890344 0.055318462209142 1.0 0.3233774411110041 40 P22830,Q9NR77,Q8N0X7,Q14331,O75431,Q14566 6 +Neonatal breathing dysregulation 0.8115902224663514 1.9163323708285929 0.0553228030306107 1.0 0.3233774411110041 2 O15078 1 +Widely patent fontanelles and sutures 0.8859667133067062 1.915429778052536 0.0554377165771233 1.0 0.3236420463993622 4 O75844,P98175 2 +Spondyloepimetaphyseal dysplasia 0.7662562335117774 1.9138715214825857 0.0556365740305602 1.0 0.3240821808654737 7 Q96L58,Q7RTS9,O95831 3 +Sensory axonal neuropathy 0.6260203325756779 1.9137462306966135 0.0556525888380994 1.0 0.3240821808654737 15 Q8IV08,O95831 2 +Abnormal diaphysis morphology 0.420366819471683 1.91142910016641 0.0559494600193981 1.0 0.324485114405476 80 Q9HC07,Q7RTS9,Q13126,Q9Y366,Q9NR77,P16278,Q8WVQ1,Q8N0X7,Q96L58,Q9Y487,O75718,Q14739,O00754,Q15056,O15078,P08236,O75431,P51798,P11274,Q9NX62,Q01082,Q96HY6,Q9NUQ7,Q9UIG0 24 +Enlarged thorax 0.5897622353815529 1.9048946275188656 0.05679376976384 1.0 0.3270392169672428 17 P04066,Q7RTS9,Q14739,P02545,O75844 5 +Abnormal platelet volume 0.7388300694934354 1.9023595475049135 0.0571241657142711 1.0 0.3277234544126148 8 P35579,P12814,Q14739 3 +Abnormality of facial adipose tissue 0.8820793880409618 1.9004459927662036 0.0573746160675263 1.0 0.3287544277013501 4 O75844,Q03252 2 +Abnormality of the biliary system 0.3821323220604519 1.8979037794193887 0.0577087584183713 1.0 0.3295023624038035 130 P22830,P55263,Q14108,O15118,P14174,Q71SY5,P02545,P39210,O00192,Q9UBM7,Q16625,A2RRP1,P11166,P49748,O75787,Q14739,Q6PGP7,O14936,P07602,O15078,Q15056,O96028,P04066,P61916,Q15437,Q01082,O43681,Q9NUN5,Q9UIG0 29 +Abnormal morphology of the musculature of the neck 0.6060434494513731 1.8971749395079291 0.057804853198965 1.0 0.3295023624038035 16 O75569,Q99720,Q96L58 3 +Abnormality of corneal size 0.455207158904098 1.8967867066553936 0.0578560944984325 1.0 0.3295023624038035 48 Q13045,Q9UQE7,Q15555,Q8NCH0,Q15056,O15078,Q96L58,O43505,P52732,Q71SY5,Q8NAT1,Q9H9S5,O96028,Q96EK5,Q9UIG0 15 +Renal dysplasia 0.6050897454118984 1.8916742217938145 0.0585344000004839 1.0 0.3313856967661277 16 O43505,O75306,Q9H9S5,Q969N2,Q9NWS8,O14936 6 +Tachycardia 0.545780948200356 1.891550444782305 0.058550903817554 1.0 0.3313856967661277 26 P23786,O43772,P02545,P42892,P09493,Q8NFF5,P50336 7 +Urinary glycosaminoglycan excretion 0.7361854224814919 1.890561921081003 0.0586828474267306 1.0 0.3313856967661277 8 P16278,P04066,P15586,P34059,P08236,P54802 6 +Abnormal erythrocyte sedimentation rate 0.7361741508559755 1.890511610284124 0.0586895692787869 1.0 0.3313856967661277 8 P14174 1 +Telangiectasia 0.4684231263083952 1.8870892828683845 0.0591483179332834 1.0 0.3328407135511221 44 P03886,O95155,Q96JJ3,Q8IZA0,P00846,O75306,Q15437,Q14739,P02545,P10619,P06280 11 +Sea blue histiocytosis 0.9019230769230772 1.8869865670834869 0.0591621324280668 1.0 0.3328407135511221 3 P16278,O15118 2 +Achilles tendon contracture 0.6630245746681022 1.8851704355719523 0.0594068309467936 1.0 0.3329248030940087 12 O60313,Q8N2K0,P50402,Q8WXH0,Q8TD16,P02545,Q9H9S5 7 +Sensory ataxia 0.8412444811669102 1.8847496096777188 0.0594636510798423 1.0 0.3329248030940087 5 Q9NR77,P54802 2 +Shield chest 0.802457886947761 1.883700417862031 0.0596055098888947 1.0 0.3331793242413279 6 Q7RTS9 1 +Redundant neck skin 0.8023734466339962 1.8833532863081697 0.0596525065136184 1.0 0.3331793242413279 6 Q9Y487 1 +Thickened ribs 0.8774388568287872 1.8825339268525376 0.0597635579282678 1.0 0.3333988639767833 4 P16278,P15586,P54802 3 +Pseudoarthrosis 0.9005494505494509 1.881723091189893 0.0598736228349907 1.0 0.3336123804726643 3 P02545,O75844 2 +Abnormality of pulmonary circulation 0.5155059427316259 1.8806570679909296 0.0600185833038822 1.0 0.3338128590952844 31 P03886,P20674,Q14108,Q8IZA0,Q9NZ08,P02545,Q71SY5,O14678,P25705,P51798,O75844,P00403 12 +Duplication of the distal phalanx of hand 0.8033507278220255 1.8804022953595565 0.0600532709713057 1.0 0.3338128590952844 2 Q8WVQ1 1 +Metaphyseal dysplasia 0.6518070217359038 1.8789143768830807 0.0602561854447794 1.0 0.3343431198562384 13 Q7RTS9 1 +Proximal muscle weakness in lower limbs 0.5606016167408693 1.878648078258563 0.0602925617472622 1.0 0.3343431198562384 21 P02545,Q96RR1,Q13049,P07196,Q00796 5 +Broad foot 0.6510702736325769 1.8750676226918552 0.0607834210940139 1.0 0.3356453419393827 13 Q7RTS9,O95831 2 +Lissencephaly 0.4325000743038351 1.8748286029738663 0.0608163068459135 1.0 0.3356453419393827 62 P20700,P07942,Q86XL3,Q9NWS8,P23786,Q9Y487,P35606,Q15392,O43505,Q8NAT1,P11177,Q6ZXV5,Q9H9S5,Q9BSJ2,Q9HC21,Q96EK5,Q16625,O14936 18 +Abnormality of the glabella 0.7996056801047066 1.8719689883499593 0.0612108940346087 1.0 0.3370655319539358 6 O96028,Q01082 2 +Opsoclonus 0.8000549299642947 1.8660031082536988 0.0620409306271778 1.0 0.3390136080763264 2 P51798 1 +Short stepped shuffling gait 0.8000549299642942 1.8660031082536972 0.062040930627178 1.0 0.3390136080763264 2 Q14203 1 +Spontaneous recurrent epistaxis 0.8000549299642923 1.8660031082536892 0.0620409306271791 1.0 0.3390136080763264 2 P35579 1 +Motor neuron atrophy 0.5556903473437607 1.8638976201511408 0.0623360830090062 1.0 0.3390136080763264 22 Q99720,Q15165 2 +Hypoplasia of the musculature 0.7969619314712146 1.8610838040127315 0.0627323429976915 1.0 0.3390136080763264 6 Q9NR77 1 +Epiretinal membrane 0.7986816808569066 1.859998948960069 0.0628856746636072 1.0 0.3390136080763264 2 P04439 1 +Retinal perforation 0.7986816808569066 1.859998948960069 0.0628856746636072 1.0 0.3390136080763264 2 P04439 1 +Ovarian papillary adenocarcinoma 0.7986816808569066 1.859998948960069 0.0628856746636072 1.0 0.3390136080763264 2 P31749 1 +Dysgerminoma 0.7986816808569066 1.859998948960069 0.0628856746636072 1.0 0.3390136080763264 2 P31749 1 +Progressive visual field defects 0.7986816808569066 1.859998948960069 0.0628856746636072 1.0 0.3390136080763264 2 O43395 1 +Epigastric pain 0.798681680856905 1.8599989489600612 0.0628856746636083 1.0 0.3390136080763264 2 Q9NWH9 1 +Splanchnic vein thrombosis 0.798681680856905 1.8599989489600612 0.0628856746636083 1.0 0.3390136080763264 2 Q9NWH9 1 +Retinal fold 0.7986816808569049 1.8599989489600612 0.0628856746636083 1.0 0.3390136080763264 2 P52732 1 +Portal vein thrombosis 0.798681680856905 1.8599989489600612 0.0628856746636083 1.0 0.3390136080763264 2 Q9NWH9 1 +Vitreoretinopathy 0.7986816808569032 1.8599989489600532 0.0628856746636095 1.0 0.3390136080763264 2 O15484 1 +Retinal neovascularization 0.7986816808569032 1.8599989489600532 0.0628856746636095 1.0 0.3390136080763264 2 O15484 1 +Abnormal astrocyte morphology 0.581892438818286 1.8577362536795443 0.0632064775184906 1.0 0.3395612728652323 17 P20585,P00846,O95831 3 +Abnormality of the musculature of the lower limbs 0.5240361794203922 1.853980040694345 0.0637420155441825 1.0 0.3419494079872846 29 Q9NR77,P00846,Q14331,P02545,Q9H9S5,Q13049,P07196 7 +Epiphyseal dysplasia 0.7522647750216063 1.85358762931968 0.0637981787658652 1.0 0.3419494079872846 7 Q96L58,Q9HC07,Q7RTS9 3 +Prominent ear helix 0.8912087912087916 1.8458739346087265 0.0649105121434749 1.0 0.3467116665870439 3 P02545,O75844 2 +Flaring of rib cage 0.8672053255231869 1.842938769902167 0.0653379508759157 1.0 0.3478296945668105 4 P16278,Q7RTS9 2 +Abnormal circulating carbohydrate concentration 0.4629111193832218 1.8386497258194316 0.065966722371868 1.0 0.3499432910549943 44 P03886,Q70HW3,O43676,O75251,O95831,Q9BWD1,O75380,Q96RR1,Q96CU9,Q00796 10 +Intracellular accumulation of autofluorescent lipopigment storage material 0.8892857142857147 1.8384809576589185 0.0659915653050742 1.0 0.3499432910549943 3 O75503,Q9NWW5 2 +Oligosacchariduria 0.8290670196678206 1.8362559140504036 0.0663198166290701 1.0 0.3510104813572824 5 P16278,P04066,P10253 3 +Talipes calcaneovalgus 0.790139381522729 1.832944027467739 0.0668108953647621 1.0 0.3528070804091474 6 Q9NR77,P07196 2 +Hypoplastic ilia 0.6696962662863944 1.8272967674361391 0.0676551610102857 1.0 0.3561137905658193 10 Q96L58,Q7RTS9,O75530 3 +Abnormal circulating acetylcarnitine concentration 0.7219253588046233 1.8267201192305256 0.0677418616392862 1.0 0.3561137905658193 8 Q9NUN5,O43772 2 +Fever 0.409515981320529 1.8266494824128616 0.0677524883580984 1.0 0.3561137905658193 93 Q9NR77,P03886,P07602,P23786,P28070,Q9HC07,P00846,Q9NZ08,P14174,O43707,Q01082,Q14739,P10253,Q8N1F7,P00813,P11274,P06280 17 +Abnormal ossification involving the femoral head and neck 0.826268908781527 1.8250848071584096 0.0679882324938911 1.0 0.3561908865829902 5 Q96L58,Q7RTS9,Q14739 3 +Abnormality of temperature regulation 0.3947042276839199 1.8196561055963816 0.0688113917745878 1.0 0.3596923932244203 114 Q9HC07,O43772,P14174,P10253,P06280,Q9NR77,P49748,P28070,Q14739,P00813,O14936,P03886,P20700,P07602,P23786,P00846,O43707,Q8N1F7,P11274,Q9NZ08,Q01082 21 +Peripheral axonal degeneration 0.4121670316270953 1.8174263403264097 0.069151857559023 1.0 0.3610659349177306 79 P02545,P39210,Q9HC21,O60313,Q9BQT8,O95831,Q9BPX6,Q96RR1,Q6DKK2,P00403,P03886,P07602,Q15046,Q8IV08,P00846,Q7LG56,Q9Y4W6,P41440,P17480,P07196 20 +Migraine 0.5188353570624489 1.8164738772010347 0.069297711581898 1.0 0.3611957282981927 29 P03886,P11166,O60313,Q9Y6N5,Q9NZ08,Q7LG56,Q96RR1,P05067 8 +Head titubation 0.7433230479129251 1.8148833518629648 0.0695418374916454 1.0 0.3611957282981927 7 P20700,Q99720 2 +Corneal opacity 0.4206273068449862 1.8147304121827017 0.0695653490051393 1.0 0.3611957282981927 66 P02545,Q9Y5Z9,Q9UBM7,P06280,Q16625,P16278,O60566,P10619,O00754,Q15056,O15078,O43505,P52732,Q9H9S5,P08236,O96028,P04066,O75569,Q8NAT1,O75844,Q9UIG0 21 +Abnormality of circulating leptin level 0.8585464114031136 1.8093368985932097 0.0703986798653089 1.0 0.3644562531238495 4 P02545,O75844 2 +Abnormal circulating non proteinogenic amino acid concentration 0.6921968559421867 1.8091442093864707 0.0704286023897604 1.0 0.3644562531238495 9 P03886,P05067 2 +Neurofibrillary tangles 0.857653201428944 1.8058656436373957 0.0709393287596733 1.0 0.3657021353467785 4 P05067,O15118,P61916 3 +Abnormal autonomic nervous system physiology 0.5054734813241722 1.8057202116678177 0.0709620539272648 1.0 0.3657021353467785 31 P07602,P42892,O43681,P41440,P06280,P50336 6 +Gingival fibromatosis 0.8806045449483266 1.805056671367148 0.0710658143451963 1.0 0.3657021353467785 3 Q15392 1 +Supraventricular tachycardia 0.8799217839307361 1.8024244230426665 0.0714786555195696 1.0 0.3658164231271368 3 P02545 1 +Mucosal telangiectasiae 0.6553934047643211 1.7994525101817591 0.071947129648024 1.0 0.3678089235141561 11 Q8IZA0,P10619,Q15437 3 +Skin rash 0.5455052620082718 1.7974129968201693 0.0722700789529842 1.0 0.3679776370701645 22 Q9NUN5,P14174 2 +Enterocolitis 0.7843998901400696 1.7974033933090938 0.0722716024362055 1.0 0.3679776370701645 2 P49748 1 +Wide cranial sutures 0.7392684378595563 1.7972883947308922 0.0722898476407722 1.0 0.3679776370701645 7 P02545,O75844,P98175 3 +Abnormality of the temporomandibular joint 0.8553255747064683 1.7968154816640045 0.0723649177460896 1.0 0.3679776370701645 4 O75844 1 +Mild short stature 0.8553075337525345 1.7967453111274392 0.0723760620361804 1.0 0.3679776370701645 4 Q13555,Q8WVQ1 2 +Delayed fine motor development 0.6628926686314238 1.7939248093498097 0.0728251709726237 1.0 0.369385811880024 10 Q5KU26,Q01082,O75175,P51798 4 +Premature graying of hair 0.6888675198708205 1.7935094708547992 0.0728914976315864 1.0 0.369385811880024 9 Q13126 1 +Thoracic kyphosis 0.5710872206465033 1.7926415130817013 0.0730302640285434 1.0 0.3694426527596677 17 O00754,Q7RTS9,Q9UHX1,O95831 4 +Vacuolated lymphocytes 0.8771978021978026 1.7919176949109148 0.0731461510567414 1.0 0.3694675695224758 3 P16278,P04066 2 +Anterior rib cupping 0.8171833880848768 1.7887408625194283 0.0736565588432505 1.0 0.369921053060386 5 O95831 1 +Neck flexor weakness 0.7794434681385243 1.788688808135538 0.0736649463833458 1.0 0.369921053060386 6 Q99720 1 +Progressive visual loss 0.5204760435673164 1.7884477723957166 0.0737037947334953 1.0 0.369921053060386 28 P03886,Q15051,O60313,Q15046,O15078,P50897,P00846,O75306,O14773,Q9NWW5,O75503 11 +Abdominal distention 0.5354942624392471 1.788387224122963 0.0737135560864896 1.0 0.369921053060386 25 P07602,Q7RTS9,O43681,Q96HY6,Q9Y366 5 +Abnormal sternum morphology 0.3862688381180965 1.7873985715695708 0.0738730923395956 1.0 0.3702512377935252 120 P98175,Q7RTS9,Q71SY5,Q8N201,P02545,P06753,Q9Y366,P16278,O60566,Q9UHX1,Q8NCH0,Q96L58,Q9Y487,Q96JJ3,O75718,O95831,Q14739,Q969N2,O00754,P55011,Q15056,P08236,O75431,O96028,P17480,P31749,P55795,Q9UQE7,Q15555,Q9NWH9,Q15437,Q9UIG0 32 +Abnormal lymphocyte morphology 0.4764286558331542 1.7847369618878717 0.0743039925885469 1.0 0.3703274472751567 37 P16278,Q13432,O00754,Q13043,P04066,P26038,P28070,O75787,Q03252,P42224,Q9Y448,O95470,P00813,Q6PGP7 14 +Decreased number of peripheral myelinated nerve fibers 0.5690980438696012 1.7806151335166258 0.0749753457817552 1.0 0.3719870164039782 17 Q9NR77,O15269,Q7LG56,P02545,Q92734,P39210,P07196 7 +Abnormality of the carpal bones 0.5690246932684822 1.7801714115299816 0.0750479125277567 1.0 0.3719870164039782 17 Q96L58,Q7RTS9,Q8WVQ1 3 +Increased adipose tissue 0.8507397345732509 1.778966728770112 0.0752452168425741 1.0 0.3719870164039782 4 P02545,O75431 2 +Abnormal periventricular white matter morphology 0.4679695126667813 1.7785646731836156 0.0753111601441887 1.0 0.3719870164039782 40 Q9UHX1,P07602,Q93009,P11177,Q9H9S5,O43681,O75503,O96028 8 +Peroneal muscle atrophy 0.849940650088018 1.7758541162080532 0.0757569653554752 1.0 0.3719870164039782 4 Q9NR77 1 +Abnormality of the cerebrospinal fluid 0.3608532117281473 1.7749112274577947 0.0759125461557761 1.0 0.3719870164039782 161 P07942,P39210,O00192,Q9HC21,Q9UBM7,Q7KZN9,Q16625,Q9NR77,P11166,O60566,Q96L58,O43676,Q15392,O95831,O75251,P00403,P03886,P20700,O00754,P55011,P07602,Q15046,O15078,P23786,Q8WXW3,P00846,O43505,Q7LG56,Q03252,Q9H9S5,P08236,P51798,O15287,O96028,Q96CU9,P31749,Q9NWS8,O75306,Q8NAT1,Q01082,P15291,Q93009,O43681,O75380,O60826 45 +Genu valgum 0.4644629990070856 1.7724897479367792 0.0763132956247023 1.0 0.3719870164039782 41 Q9NR77,P16278,O00754,Q15056,Q8N0X7,O95714,Q96L58,Q9NX62,Q7RTS9,Q9UIG0,Q01082,P08236,O75431,P51798,Q9Y619,Q96L73 16 +Bifid scrotum 0.7754508461623626 1.7721262927113852 0.0763735953116848 1.0 0.3719870164039782 6 Q01082,Q96EK5,Q9UBM7 3 +Cold induced muscle cramps 0.8716683720724371 1.770565936178443 0.0766329106792897 1.0 0.3719870164039782 3 Q9NR77 1 +Multiple glomerular cysts 0.8715242051294257 1.7700088132068157 0.0767256725770435 1.0 0.3719870164039782 3 P03886 1 +Leber optic atrophy 0.8715242051294257 1.7700088132068157 0.0767256725770435 1.0 0.3719870164039782 3 P03886 1 +Low plasma citrulline 0.8715242051294257 1.7700088132068157 0.0767256725770435 1.0 0.3719870164039782 3 P03886 1 +Retinal arterial tortuosity 0.8715242051294257 1.7700088132068157 0.0767256725770435 1.0 0.3719870164039782 3 P03886 1 +Diminished ability to concentrate 0.8119402998730598 1.7677189332896035 0.0771079031683719 1.0 0.3726968647911737 5 Q96RR1,Q7RTS9 2 +Type ii lissencephaly 0.811869932908751 1.7674365630809843 0.0771551441661686 1.0 0.3726968647911737 5 P07942,Q9H9S5,O43505 3 +Deviation of the 2nd finger 0.7742076853314839 1.7669646602024207 0.0772341469321928 1.0 0.3726968647911737 6 Q71SY5,Q9Y448,Q8WVQ1 3 +Ascending tubular aorta aneurysm 0.8112699215123649 1.7650285703132016 0.0775589641615273 1.0 0.3731590518359304 5 P02545,O75844 2 +Abnormal peripheral action potential amplitude 0.6568765314473521 1.7643299205433665 0.0776764492998016 1.0 0.3731590518359304 10 O15269,P39210,Q00796 3 +Decreased adipose tissue 0.5990967047170231 1.7630385880189663 0.0778939816657611 1.0 0.3731590518359304 15 O75844,O75431,Q03252 3 +Elevated pulmonary artery pressure 0.5317256752170394 1.7627956941624543 0.0779349539061127 1.0 0.3731590518359304 25 P03886,Q14108,Q8IZA0,P02545,Q71SY5,O14678,P25705,P51798,O75844,P00403 10 +Aplasia hypoplasia involving bones of the lower limbs 0.3982658544534148 1.7625741820262262 0.077972334696081 1.0 0.3731590518359304 104 O00116,Q7RTS9,P02545,Q8N3R9,Q9Y366,Q9UBM7,Q9UHX1,Q8WVQ1,Q8N0X7,Q96L58,O95831,P00813,P55011,O95155,Q9Y448,O75431,O96028,Q9UQE7,Q9NX62,Q13555,Q9NWH9,Q93009,Q96HY6 23 +Central scotoma 0.6294503373929322 1.76155686143305 0.0781441979056603 1.0 0.3735967980119376 13 P03886,O60313,P00846,O75306,Q8NHS3,Q9H6K4 6 +Abnormality of krebs cycle metabolism 0.7727748242508087 1.761012669776999 0.0782362586067786 1.0 0.3736525115577598 6 P03886 1 +Episodic respiratory distress 0.8457308459114927 1.759444096529512 0.0785021076411351 1.0 0.3745372630475926 4 P03886 1 +Weakness of muscles of respiration 0.4752684159711818 1.756247523576704 0.079046153288476 1.0 0.3760375065581236 36 Q7RTS9,Q8TD16,O95831,P02545,P06753,P10253,P50336 7 +Abnormal vitamin b12 level 0.7062192161968621 1.7559712110660526 0.0790933243739564 1.0 0.3760375065581236 8 P41440,Q9NUN5 2 +Postnatal growth retardation 0.4149610170211625 1.7543635854758923 0.0793682267818014 1.0 0.3767355974004406 66 P11166,A2RRP1,O60566,Q9UQE7,Q96L58,Q9Y487,Q7RTS9,P02545,P08236,O75431,O96028,O60826,O14936 13 +Avascular necrosis 0.5361124414903244 1.7530118995443982 0.0795999645416034 1.0 0.3774500359437053 23 O00754,Q14108,Q8IWS0,O75844,Q9NZ08,P02545,P51798,Q9NUQ7,Q9Y619 9 +Cutaneous photosensitivity 0.530116405625069 1.7518505708674257 0.0797995058324296 1.0 0.3776255637508153 25 P22830,Q9UBM7,Q14108 3 +Decreased absent ankle reflexes 0.5807036825313062 1.7500387788501777 0.0801116224842413 1.0 0.3783320220368591 16 O60313,O75787,Q7LG56,Q96RR1,P07196 5 +Peripheral axonal neuropathy 0.4174864719489959 1.7488380956335112 0.0803190096410755 1.0 0.3789263327939877 64 P03886,O60313,P07602,Q8IV08,Q96RR1,Q15046,P00846,Q7LG56,O95831,Q9Y4W6,P39210,Q5TAQ9,Q9BPX6,Q9HC21,P07196,P00403 16 +Abnormal large intestine physiology 0.5349498701012252 1.7452820393306083 0.0809357867560238 1.0 0.3814488854515648 23 P20700,P07602,O75298,O43681,P11274,P06280 6 +Metaphyseal cupping 0.864701055426286 1.743616989793677 0.0812258987349916 1.0 0.3822862212625929 3 O95831 1 +Barrel shaped chest 0.8053528238654064 1.7412577826235698 0.081638402772582 1.0 0.3833602896845655 5 Q7RTS9,P04066 2 +Palmar telangiectasia 0.7714913485306214 1.7405993606724917 0.0817538297993123 1.0 0.3833602896845655 2 Q14739 1 +Aplasia hypoplasia involving the femoral head and neck 0.6513851315932278 1.7372477280771563 0.0823434537111267 1.0 0.3853474616269948 10 Q96L58,Q96HY6,O75431,O95831 4 +Eeg with frontal epileptiform discharges 0.7703927492447114 1.7357555675469387 0.082607063573703 1.0 0.3854302922597431 2 P42356 1 +Abnormal atrioventricular conduction 0.6239537175001129 1.7325098439532924 0.0831828259298192 1.0 0.3877137332957575 13 P02545,O43772,P49748,P06280 4 +Abnormal ilium morphology 0.5352691451737907 1.730197447619105 0.0835950042241417 1.0 0.388155841075173 22 P16278,Q7RTS9,O75530,O95831 4 +Gray matter heterotopia 0.4953847580808364 1.729884160320166 0.0836509738261084 1.0 0.388155841075173 31 P07942,Q86XL3,P35606,O43505,P11177,Q6ZXV5,Q9H9S5,Q9NXR1,Q9BSJ2,Q9UBM7,Q9UEY8 11 +Abnormality of subcutaneous fat tissue 0.5771818230997263 1.7294318176388763 0.083731839572041 1.0 0.388155841075173 16 Q9Y487,O75844,O75431 3 +Cardiac conduction abnormality 0.4827866183284305 1.729169024516485 0.0837788484179897 1.0 0.388155841075173 33 P03886,P49748,P23786,P00846,O43772,Q7LG56,P02545,P06280 8 +Occipital encephalocele 0.7648475652928111 1.7280316059401868 0.0839825580885451 1.0 0.3887120990413041 6 Q6ZXV5,P07942,Q9H9S5,O43505 4 +Neoplasm of the gallbladder 0.8373186714068463 1.7265943645050008 0.084240538750627 1.0 0.388928999413115 4 P07602 1 +Biliary tract neoplasm 0.8373186714068463 1.7265943645050008 0.084240538750627 1.0 0.388928999413115 4 P07602 1 +Anophthalmia 0.6078325038298813 1.7255603772470949 0.0844265328449558 1.0 0.388928999413115 14 O15078,O75569,O43505,P52732,Q96N67,Q9H9S5 6 +Abnormality of long bone morphology 0.3704908461527414 1.7227544701649449 0.0849329354574468 1.0 0.3890306297193693 192 O00116,P98175,Q9HC07,Q7RTS9,Q71SY5,P02545,Q13126,Q8N3R9,Q9Y366,Q9UBM7,Q9NR77,P16278,Q9UHX1,Q8WVQ1,Q8N0X7,Q96L58,Q9Y487,O75718,O95831,Q14739,Q13868,P00813,Q969N2,O14936,O00754,P55011,Q15056,O15078,Q9Y448,P08236,O75431,O75530,O96028,P48735,P11274,Q15051,Q9NX62,Q9NWH9,Q01082,Q96HY6,O75844 41 +Hyporeflexia of upper limbs 0.8591626673190228 1.7221604538893516 0.0850404563890285 1.0 0.3890306297193693 3 Q9NR77 1 +Upper airway obstruction 0.8361068477035749 1.721855863646682 0.0850956319440956 1.0 0.3890306297193693 4 P02545,O75844 2 +Stenosis of the external auditory canal 0.7218733508637336 1.7214972053461328 0.0851606388649779 1.0 0.3890306297193693 7 O96028 1 +Hypoplasia of the brainstem 0.4879678126122292 1.7199824028986055 0.085435640325836 1.0 0.3890306297193693 32 P07942,Q9HD42,O43505,Q10713,P11177,Q6ZXV5,Q9H9S5,Q9NXR1,Q96EK5,Q9Y3C6,O14936 11 +Narrow nasal ridge 0.7213233417662942 1.7190929327324398 0.0855974514545407 1.0 0.3890306297193693 7 O75844,O75431 2 +Hallucinations 0.4493960056058496 1.7190793931789317 0.0855999164632008 1.0 0.3890306297193693 44 O00754,P07602,Q8N0X7,P50897,O96008,O43681,Q9NWW5,O75503,Q6DKK2,P05067,P50336 11 +Shoulder girdle muscle atrophy 0.7997799027511653 1.71883046935204 0.0856452457149516 1.0 0.3890306297193693 5 P06753,Q9H9S5,Q13049 3 +Recurrent respiratory infections 0.3598863903021679 1.716658565956792 0.0860415748913654 1.0 0.3890306297193693 137 P26038,Q7RTS9,P14174,Q71SY5,P06753,P10253,P54802,Q13432,P16278,Q9Y487,P02786,P15586,P00813,P20700,P07602,Q15056,P08236,P51798,O96028,P11274,P04066,Q86YV9,O60826,Q9UIG0 24 +Erythema 0.5249166469759671 1.7164171191305615 0.0860857255055049 1.0 0.3890306297193693 25 P22830,P03886 2 +Skeletal dysplasia 0.4392504627575137 1.7163317559776554 0.0861013392656475 1.0 0.3890306297193693 47 P16278,Q8WVQ1,Q96L58,Q9HC07,Q7RTS9,Q14739,O95831,Q96HY6,P10619 9 +Micromelia 0.527821791468033 1.7161498253634662 0.0861346237980922 1.0 0.3890306297193693 24 Q9UQE7,Q9UHX1,Q15392,O75718,Q14739,Q96HY6,Q9UBM7,P48735 8 +Lagopthalmos 0.8575187230678072 1.7157858343265546 0.0862012478135509 1.0 0.3890306297193693 3 O75844 1 +Leukoencephalopathy 0.3963699114347393 1.7155416186800252 0.0862459717689569 1.0 0.3890306297193693 101 P07942,Q01105,O75503,Q9UHX1,O43676,O95831,O75251,Q9BUB7,P03886,P20700,P07602,Q7LG56,P11177,Q9H9S5,O96028,Q96CU9,O00584,O75306,Q93009,O43681,Q9NWW5,O75380 22 +Metatarsus valgus 0.8342951360263715 1.7147687647742496 0.0863876303869028 1.0 0.3890306297193693 4 Q8NAT1,Q9H9S5,O43505 3 +Autoimmunity 0.4604272020718837 1.7146172204951693 0.0864154293986978 1.0 0.3890306297193693 40 Q8IZA0,Q15437,Q03252,P14174,O00192,P00813 6 +Abnormal lung development 0.4275284552325595 1.713603041223269 0.0866016546417718 1.0 0.3890306297193693 51 O60566,Q9UHX1,P98175,Q96L58,O96028,O75844,O75419,P02545,Q14739,Q5JTZ9,P25705,O00192,Q9UBM7,Q969N2,Q5H8A4,P31749 16 +Short lingual frenulum 0.8558461297070066 1.7092974763684368 0.0873958605520677 1.0 0.3908840846828283 3 O75844 1 +Overtubulated long bones 0.8558461297070066 1.7092974763684368 0.0873958605520677 1.0 0.3908840846828283 3 O75844 1 +Centrally nucleated skeletal muscle fibers 0.6955175031168105 1.7075162428056845 0.0877261413905028 1.0 0.3919840183092948 8 Q9BPX6,P06753,Q13049 3 +Abnormal renal cortex morphology 0.4208044463583378 1.7053031897083697 0.0881378930135003 1.0 0.3930679355410137 58 P03886,Q14108,O15078,P00846,Q9NZ08,O43707,P02545,Q03252,O75431,Q8N1F7,P00813,P06280 12 +Heinz bodies 0.7629772040648152 1.7030232758322483 0.0885637126403304 1.0 0.3939456145404887 2 O14936 1 +Reduced subcutaneous adipose tissue 0.6695648226542964 1.702435327468052 0.0886737922981173 1.0 0.3939456145404887 9 O75844 1 +Central apnea 0.6691302796046308 1.700376908739005 0.0890600523886679 1.0 0.3950604828588226 9 P11166,P07602,O15078,Q8N3U4,O76024,Q10713,Q14683 7 +Somatic sensory dysfunction 0.3777207077767497 1.7001922592576135 0.0890947678149443 1.0 0.3950604828588226 122 Q71SY5,P02545,O75298,P39210,P54802,O14773,P06280,P05067,Q00796,Q9NR77,P11166,Q8NCH0,O95831,Q96RR1,P50336,P20700,P07602,Q8IV08,P00846,Q9Y448,P41440,Q9NZ08,P07196 23 +Abnormal pleura morphology 0.517387860136389 1.6960443075506944 0.0898774894110781 1.0 0.3971397238390057 26 Q8NCH0,Q96L58,Q9NZ08,P52732,Q14739,P14174 6 +Angioid streaks of the fundus 0.7613293051359495 1.695740982443776 0.0899349435998528 1.0 0.3971397238390057 2 P31749 1 +Cupped ribs 0.71597486047486 1.6956886336805113 0.0899448622080139 1.0 0.3971397238390057 7 P00813,O95831 2 +Loss of speech 0.5344215586133674 1.6950625267421664 0.0900635599980663 1.0 0.3971397238390057 20 P07602,O15118,P61916,P50897,O43681 5 +Oval face 0.7157072491694282 1.694516452264306 0.090167188078166 1.0 0.3971397238390057 7 Q96L58,Q01082,Q9UHX1,O14936 4 +Frontotemporal dementia 0.6661238594839324 1.6861260576139043 0.0917715220186283 1.0 0.4003598514291943 9 P05067,Q14203 2 +Impaired vibratory sensation 0.4644359993076076 1.686108069525989 0.0917749860152925 1.0 0.4003598514291943 37 Q9NR77,P20700,P00846,O75298,O14773,Q96RR1,P07196,Q00796 8 +Retinopathy 0.4705492789078963 1.6842519499801725 0.0921329872375633 1.0 0.4008812250430794 34 Q15555,P00846,Q9NZ08,O75306,P52732,Q8NHS3,O96028,Q13049 8 +Cardiorespiratory arrest 0.8257519610603388 1.6813034801567115 0.0927039822658253 1.0 0.4008812250430794 4 O43772 1 +Testicular dysgenesis 0.7577588574567407 1.679952505136781 0.0929665569122661 1.0 0.4008812250430794 2 Q9H0U9 1 +Ovarian gonadoblastoma 0.7577588574567407 1.679952505136781 0.0929665569122661 1.0 0.4008812250430794 2 P51809 1 +Abnormal sex determination 0.7577588574567407 1.679952505136781 0.0929665569122661 1.0 0.4008812250430794 2 P51809 1 +Female external genitalia in individual with 46 xy karyotype 0.7577588574567407 1.679952505136781 0.0929665569122661 1.0 0.4008812250430794 2 P51809 1 +Hypoplasia of the vagina 0.7577588574567407 1.679952505136781 0.0929665569122661 1.0 0.4008812250430794 2 P51809 1 +Toxemia of pregnancy 0.7532923512134136 1.6798039187162273 0.0929954724761006 1.0 0.4008812250430794 6 P02545,Q01082,O43772 3 +Flat face 0.5145278920561334 1.6761737567647168 0.0937041629864579 1.0 0.4014159122152944 26 O00754,Q15555,Q9NX62,Q96L58,Q9Y487,Q13555,P08236,Q9BUB7 8 +Falls 0.6886135761266855 1.6761545384796328 0.0937079263296021 1.0 0.4014159122152944 8 Q01082,O75787 2 +Abnormal muscle fiber protein expression 0.7113745651170094 1.675523614816513 0.0938315417440414 1.0 0.4014159122152944 7 P50402,Q8WXH0,P02545,Q9H9S5,Q13642 5 +Decreased calvarial ossification 0.8242473561886683 1.6754019879316573 0.0938553868474092 1.0 0.4014159122152944 4 P02545,O75844 2 +Increased bone mineral density 0.5096035493773312 1.6749522821066731 0.0939435944443543 1.0 0.4014159122152944 27 Q14108,Q15056,Q15392,Q14739,P02545,Q13126,P54802,P51798 8 +Aplasia hypoplasia involving bones of the feet 0.3995443406866073 1.673404197404671 0.0942477521111875 1.0 0.4014159122152944 79 Q9Y366,Q9UQE7,P55011,Q9UHX1,O95155,Q8WVQ1,Q9NX62,Q8N0X7,Q13555,Q7RTS9,P02545,Q9Y448,Q8N3R9,P00813,Q9UBM7,O96028 16 +Hand muscle weakness 0.6377708838140189 1.6698322412550386 0.0949525594811828 1.0 0.4014159122152944 10 Q9NR77,Q8TD16,P07196 3 +Mitochondrial respiratory chain defects 0.6870082139763862 1.6688508861907454 0.0951469350921407 1.0 0.4014159122152944 8 P03886,P00846 2 +Increased sulfur amino acid level in urine 0.7501680014401759 1.66673391583586 0.0955673257855371 1.0 0.4014159122152944 6 Q9NUN5,Q4J6C6 2 +Distal amyotrophy 0.4110240632289754 1.6662452059347448 0.0956645854155584 1.0 0.4014159122152944 63 Q9NR77,Q99720,Q8N0X7,Q7Z406,Q8TD16,P02545,Q71SY5,P06753,P39210,P07196 10 +Uveitis 0.6369627054572932 1.6658183735636474 0.0957495954295499 1.0 0.4014159122152944 10 P14174 1 +Abnormal circulating arginine concentration 0.7544630595990092 1.6653664814543634 0.0958396623586146 1.0 0.4014159122152944 2 Q9NVS9 1 +Central nervous system cyst 0.4081016502143385 1.664928291148807 0.0959270631254138 1.0 0.4014159122152944 65 Q9UHX1,O60826,O15078,P23786,Q9Y487,P00846,P80404,O43505,Q8NAT1,P11177,Q9H9S5,P15291,Q9BSJ2,O96028,Q9UBM7 15 +Cogwheel rigidity 0.6860952234989685 1.664695356654368 0.0959735498473079 1.0 0.4014159122152944 8 Q96RR1,P00846,O75787 3 +Anomalous trichromacy 0.8442523947290168 1.6642517403037829 0.096062132201816 1.0 0.4014159122152944 3 O60313 1 +Tritanomaly 0.8442523947290168 1.6642517403037829 0.096062132201816 1.0 0.4014159122152944 3 O60313 1 +Large placenta 0.8442307692307698 1.6641676050540444 0.0960789399057784 1.0 0.4014159122152944 3 P02545,O75844 2 +Agnosia 0.6614822124286025 1.6640917567406115 0.0960940941451655 1.0 0.4014159122152944 9 O96008,P05067,O75787 3 +Hypoglycemic seizures 0.7495059070025382 1.6639626000493577 0.0961199036222029 1.0 0.4014159122152944 6 P53985,Q13423 2 +Abnormality of circulating enzyme level 0.3861388987515591 1.6634621450420484 0.0962199623143964 1.0 0.4014159122152944 110 Q86VD7,Q9HC07,O43772,P02545,P06753,P10253,P39210,Q9Y6N5,P49748,Q7Z406,P53985,O95831,Q6ZXV5,Q9BPX6,Q96RR1,Q13049,Q15056,P23786,O43505,Q7LG56,Q9H9S5,P09493,Q14331,Q8NAT1,P15291,Q8NFF5,P07196 27 +Hyperactive deep tendon reflexes 0.6364192887339322 1.663118728735819 0.0962886716135758 1.0 0.4014159122152944 10 Q9NR77,P11166 2 +Abnormality of the calcaneus 0.6362801133239973 1.6624272235125594 0.0964271442038728 1.0 0.4014159122152944 10 Q7RTS9,O75787 2 +Adipose tissue loss 0.6611199056054662 1.6623702300784546 0.096438564132498 1.0 0.4014159122152944 9 O75844,O75431,Q03252 3 +Abnormality of chromosome segregation 0.7857235032185496 1.66210082916499 0.0964925593689827 1.0 0.4014159122152944 5 Q15437,Q14739 2 +Optic disc pallor 0.4163203376591721 1.6599476109027604 0.0969249922498052 1.0 0.4023934767259415 58 O60313,Q96L58,O43676,O95831,O75251,Q6P4Q7,Q9H6K4,Q8NHS3,O14936,P03886,O00754,P00846,Q9Y4W6,P51798,P04439,Q96CU9,O75306,O75380,Q9GZY8 19 +Patchy alopecia 0.8430719650014408 1.659658616173414 0.0969831491140638 1.0 0.4023934767259415 3 O75844 1 +Female hypogonadism 0.7849914734313619 1.659140338506441 0.0970875164225759 1.0 0.4024671621906427 5 O75844 1 +Reduced consciousness confusion 0.3453386864456063 1.6564825555535072 0.097624134884559 1.0 0.4036075630318644 144 O96008,O43772,Q8N3U4,Q9HC21,Q9UBM7,P05067,A2RRP1,P11166,Q9Y6N5,P49748,O43676,P80404,O75251,O14678,Q9NXR1,Q96RR1,Q5H8A4,P50336,P00403,P03886,P20674,Q9Y3D3,O00754,P07602,P23786,Q7LG56,Q9H9S5,Q96CU9,P31749,P49792,Q9NWS8,Q13423,Q9NZ08,P46783,O75306,P31751,O43681,O75380,P23378,Q9NUN5,P49770 41 +Tissue ischemia 0.5216319662800047 1.6563784148211247 0.0976452095336317 1.0 0.4036075630318644 23 Q15056,Q9NZ08,P02545,P06280,O75844,P05067 6 +Angiofibromas 0.7842295227274747 1.6560582170064466 0.0977100297849897 1.0 0.4036075630318644 5 Q15437 1 +Adenoma sebaceum 0.7842295227274747 1.6560582170064466 0.0977100297849897 1.0 0.4036075630318644 5 Q15437 1 +Rigidity 0.4148374600616269 1.6555901903042864 0.0978048381000229 1.0 0.4036403931179455 59 P16278,P07602,P00846,Q15392,O75787,Q14203,Q7LG56,P52732,Q9Y4W6,Q96F07,Q9H6K4,P49792,O43681,Q9BPX6,Q96RR1,Q96CU9,P17480,O14936 18 +Abnormal tongue morphology 0.3977317859054597 1.6530228467001948 0.0983262139183112 1.0 0.4049888439400725 80 P98175,Q71SY5,P02545,P10253,Q9UBM7,P16278,P20700,O00754,Q15056,O15078,Q03252,Q9H9S5,O75431,P11274,P04066,Q15437,Q14331,Q01082,O60826,O75844,Q9NUN5,P07196 22 +Abnormal thoracic spine morphology 0.4962784947742458 1.652437993475288 0.0984452957203982 1.0 0.4049888439400725 29 O00754,Q9UHX1,Q7RTS9,O95831,P02545,P06753,O75844 7 +Abnormality of the intrahepatic bile duct 0.7832638598851638 1.6521511618805784 0.0985037394984451 1.0 0.4049888439400725 5 P02545,Q9NUN5 2 +Memory impairment 0.441790113788875 1.6513149070975148 0.0986742899267514 1.0 0.4049888439400725 44 P03886,P07602,O96008,Q9NZ08,Q7LG56,Q9Y4W6,O43681,Q96RR1,P05067,P31749,P00403 11 +Osteomyelitis 0.5477895512056559 1.650985032435539 0.0987416311995055 1.0 0.4049888439400725 17 Q01082,Q13126,P39210 3 +Ketotic hypoglycemia 0.8406400878877732 1.6501922540200662 0.0989036206179561 1.0 0.4051213264960299 3 P53985 1 +Abnormality of the vertebral endplates 0.7055416771045948 1.649910712420822 0.0989611993876544 1.0 0.4051213264960299 7 Q96L58,Q7RTS9,P51798 3 +Orthostatic hypotension due to autonomic dysfunction 0.6579670847002261 1.6473795873370407 0.0994800483742519 1.0 0.4060871779572539 9 P07602,O43681 2 +Central diabetes insipidus 0.7503433122768448 1.6471182566521134 0.099533741272501 1.0 0.4060871779572539 2 P35222 1 +Upper limb amyotrophy 0.607056863969366 1.642765817016511 0.1004313952283282 1.0 0.4076023525118264 13 Q9NR77,P07196,Q14203 3 +Distal upper limb amyotrophy 0.6156788289701806 1.6412482595892617 0.1007458916249977 1.0 0.4084675100854173 12 Q9NR77,P07196,Q14203 3 +Hamartomatous polyposis 0.8151418325546199 1.6396405060459998 0.1010799357556013 1.0 0.4088063198052912 4 P20585,Q15437 2 +Third degree atrioventricular block 0.8373965017846365 1.637558444769866 0.1015138376728459 1.0 0.4102041771006218 3 P02545 1 +Paralysis 0.4195477332030738 1.636413433958487 0.1017530894873579 1.0 0.4108137331431384 51 P31040,P35637,P02545,P10253,Q92804,P43243,Q9HC21,Q9NR77,P11166,Q14203,O95140,P50336,P20700,Q15233,P51798,P04062,P16930,Q68CQ7,P50402,Q15165,P42356 21 +Abnormality of the pulmonary veins 0.7424008277351872 1.6341886294682575 0.1022192493283169 1.0 0.4119799233553242 6 Q15392 1 +Soft tissue sarcoma 0.4641893070217586 1.6331629566181618 0.1024347285611313 1.0 0.4124906270568261 34 Q96JJ3,Q13126,Q15392,Q15437 4 +Abnormal 2nd finger morphology 0.7016117244579628 1.6326262463876011 0.1025476276745722 1.0 0.4125877279686037 7 Q71SY5,Q9Y448,Q8WVQ1 3 +Airway obstruction 0.5756409360852215 1.630066643754818 0.1030874126101557 1.0 0.4139318240301313 15 P02545,O75844,P06280,Q96HY6 4 +Cyclopia 0.7459489151332028 1.6276350366071073 0.1036022953680806 1.0 0.4150343677374747 2 Q8N3U4 1 +Panhypopituitarism 0.7459489151332028 1.6276350366071073 0.1036022953680806 1.0 0.4150343677374747 2 Q8N3U4 1 +Flattened femoral epiphysis 0.7456742653117251 1.6264167235018625 0.1038610356076352 1.0 0.4151851507382262 2 Q9NUQ7 1 +Premature osteoarthritis 0.7456742653117241 1.626416723501859 0.1038610356076359 1.0 0.4151851507382262 2 Q96HY6 1 +Positional foot deformity 0.3763706450577367 1.6261959914673572 0.10390796864828 1.0 0.4151851507382262 118 P98175,Q9HD42,Q7RTS9,Q8TD16,P02545,P06753,O00192,Q9UBM7,Q9NR77,Q9UHX1,Q8NCH0,Q8WVQ1,Q96L58,Q9Y487,Q15392,Q6ZXV5,P32929,O00754,O15078,P08236,O75530,O96028,Q01082,P07196 24 +Heparan sulfate excretion in urine 0.8111821689384495 1.6240648013241583 0.1043619791869092 1.0 0.416351354494644 4 P15586,P54802 2 +Hypoketotic hypoglycemia 0.6770720226597595 1.6235552403194764 0.1044707647630185 1.0 0.416351354494644 8 P23786,P31751,O43772 3 +Mitral valve calcification 0.8109486825583307 1.623145915689219 0.1045582162029803 1.0 0.416351354494644 4 O75844,O75431 2 +Cardiac valve calcification 0.8109486825583307 1.623145915689219 0.1045582162029803 1.0 0.416351354494644 4 O75844,O75431 2 +Upper limb postural tremor 0.833077731140835 1.620723366072646 0.1050769801108688 1.0 0.4174032511565546 3 Q9NR77 1 +Abnormality of the lymphatic system 0.3496827085917986 1.6205422481175191 0.1051158465762613 1.0 0.4174032511565546 158 Q14108,O15118,P14174,P02545,P10253,P54802,O00192,P16278,P11166,P28070,Q15392,P15586,Q14739,P00813,P10619,O14936,O00754,O95155,P07602,O15078,P08236,O96028,P48735,P11274,P04066,P61916,Q9NZ08,Q15437,P31751,Q96HY6 30 +Tremor by anatomical site 0.4969751788067981 1.6200310485445013 0.1052256074716326 1.0 0.4174032511565546 28 Q9NR77,P20700,Q99720,P07196 4 +Mental deterioration 0.3862754918536041 1.619551214795501 0.1053287164731142 1.0 0.4174032511565546 105 Q14108,P27544,O15118,O96008,P54802,O75503,P05067,P16278,O60313,Q9Y487,Q14203,Q8NHS3,Q96RR1,P00403,P03886,P20700,P07602,Q15046,P50897,P00846,Q7LG56,Q96F07,P61916,O75306,O43681,Q9NWW5 26 +Serositis 0.520649328659603 1.6188612012296852 0.105477130458212 1.0 0.4175061543776077 21 Q9NZ08,O43707,P14174 3 +Dysmetria 0.4148546441284874 1.6175732749386174 0.1057545924402136 1.0 0.4182481626124876 55 P20700,O60313,Q15056,Q8IV08,Q8N0X7,O75787,Q7LG56,Q10713,Q9Y4W6,O75027,O14773,P42356,O75503,P41440,Q6DKK2,Q9UIG0 16 +Venous malformation 0.743477066739904 1.6166676967536278 0.1059500304 1.0 0.4186647884938778 2 P31749 1 +Thin ribs 0.6014484617529484 1.612833758350256 0.1067806297373152 1.0 0.4208732708984767 13 O75844,O75431,O95831 3 +Abnormality of upper limb joint 0.3645645819766708 1.6114166297888888 0.1070889450259859 1.0 0.4213745881082532 128 Q7RTS9,Q8IZA0,Q8WVM7,Q71SY5,P02545,P06753,Q9NR77,P16278,Q8WVQ1,Q96L58,Q15392,O95831,P42892,Q9BUB7,O95155,Q15056,P23786,O75530,O96028,P11274,Q9UQE7,Q9NUQ7,O75844,P07196,Q9UIG0 25 +Papule 0.5233459597631852 1.6114155815293256 0.107089173349655 1.0 0.4213745881082532 19 O75844,Q9NZ08,P16615,Q15437 4 +Limb girdle muscle atrophy 0.6010003739610393 1.6104393414931095 0.1073019777770103 1.0 0.4214906627538581 13 P50402,Q8WXH0,Q13642,Q14331,P02545,P06753,Q9H9S5,Q13049 8 +Abnormal speech prosody 0.6499163817735933 1.6090231618269069 0.1076112771270068 1.0 0.4219996665056545 9 P03886 1 +Type 1 muscle fiber atrophy 0.6955615564314599 1.6059747448782953 0.1082794590790887 1.0 0.4242619277744734 7 P50402,Q8WXH0,P06753,P02545 4 +Premature loss of teeth 0.5999583394602745 1.604869416452512 0.108522545369968 1.0 0.4246863761791218 13 P02545,O75844,Q969N2 3 +Progressive 0.3766168918018815 1.604489352530596 0.1086062295663872 1.0 0.4246863761791218 116 Q99720,P07942,P55263,P27544,P02545,O75298,Q13126,P39210,P54802,Q9NVC6,O60313,O00400,Q8TEQ6,Q7Z406,P57740,P15586,O95831,Q5MNZ6,Q5JTZ9,O75251,Q96RR1,P20700,Q7LG56,Q03252,Q9Y4W6,O95470,Q8N1F7,P04062,P31749,O75569,P35606,Q9NR28,O00764,Q9GZY8 34 +Chorioretinal dysplasia 0.6950733028975415 1.6038217741536271 0.1087533435879395 1.0 0.4246863761791218 7 Q9H9S5,O43505,P52732 3 +Tetraplegia tetraparesis 0.4201730215104311 1.6027484150983784 0.1089902098032817 1.0 0.4252539924062555 49 P20700,Q9UBX3,P07602,Q7RTS9,P00846,O95831,O43681,P50336 8 +Soft skin 0.6483058990852878 1.6013371485591956 0.1093022653089828 1.0 0.425882290700204 9 Q96L58,Q13126 2 +Supraventricular arrhythmia 0.5396648670000769 1.6011914022065707 0.1093345325597898 1.0 0.425882290700204 17 P50402,Q8WXH0,P00846,O95235,Q7LG56,P02545,Q96RR1,Q8NFF5,Q13642 9 +Macrovesicular hepatic steatosis 0.6480235617606248 1.5999892561241889 0.1096009668589472 1.0 0.4262056008314042 9 P23786,O75431,P39210 3 +Long upper lip 0.7393573194177376 1.598376516305792 0.1099592077451263 1.0 0.4272411692237476 2 Q96L58 1 +Shallow orbits 0.6474474904916294 1.597238658147853 0.1102125185350786 1.0 0.4276054216607335 9 O75844,O75431 2 +Abnormality of the tonsils 0.6473380586719177 1.5967160869343382 0.1103290080850483 1.0 0.4276054216607335 9 P00813,P31751 2 +Broad femoral neck 0.8038892663004331 1.5953408757548797 0.1106360296213726 1.0 0.4284305963043753 4 Q7RTS9,Q8WVQ1 2 +Abnormality of the distal phalanges of the toes 0.7330561165276483 1.594937081064665 0.110726306469024 1.0 0.4284305963043753 6 P02545,O75431,O75844,Q71SY5 4 +Subcutaneous nodule 0.5203303587713436 1.5919758531275945 0.1113901302726847 1.0 0.4300017429797584 19 P31749,P35637,Q9NZ08,Q9Y2U8,P52732,Q15437,P48735,P06280,P35222 9 +Joint subluxation 0.6923076044618239 1.5916203376116238 0.1114700375525636 1.0 0.4300017429797584 7 P16278,Q9UHX1 2 +Abnormal greater sciatic notch morphology 0.7322332744093212 1.5914759828351352 0.1115024962966664 1.0 0.4300017429797584 6 Q7RTS9,Q96HY6 2 +Aplasia hypoplasia involving bones of the thorax 0.4478646633454781 1.586515039925918 0.1126225231585211 1.0 0.4322426690598767 39 Q9UHX1,O95155,P98175,Q96L58,Q7RTS9,O75419,P02545,Q14739,O75431,Q96HY6,O60826,O75844 12 +Flat acetabular roof 0.7307891682649779 1.585399843169908 0.1128755167994619 1.0 0.4322426690598767 6 Q9Y366,Q7RTS9 2 +Decreased circulating total igg 0.7363361713814842 1.5849536349716604 0.1129768690084369 1.0 0.4322426690598767 2 Q9Y448 1 +Decreased circulating total iga 0.7363361713814842 1.5849536349716604 0.1129768690084369 1.0 0.4322426690598767 2 Q9Y448 1 +Abnormal pharynx morphology 0.4311317866537135 1.5826731535882803 0.1134959803406006 1.0 0.4322426690598767 45 P16278,O15344,Q7RTS9,P15586,Q86YV9,P08236,P54802,P00813,P29372 9 +Abnormal retinal artery morphology 0.505181625668152 1.581029563843327 0.1138712781816477 1.0 0.4322426690598767 25 P03886,P16278,P07602,Q15056,P00846,O00192,P10619 7 +Kyphosis 0.3494239429088913 1.580604459234481 0.1139685055971078 1.0 0.4322426690598767 163 Q14108,Q9HC07,Q8IWS0,Q7RTS9,Q8TD16,Q71SY5,P02545,Q5KU26,P06753,Q8N3R9,Q9UBM7,Q9NR77,P16278,Q9UHX1,Q8NCH0,Q8WVQ1,Q8N0X7,O95714,Q9Y487,Q96L58,O95831,Q5MNZ6,Q14739,Q5H8A4,Q96L73,O00754,P55011,O95155,Q15056,Q15233,Q9NWM8,P34059,Q9H9S5,P08236,O96028,P17480,P31749,P04066,Q9NUQ7,Q15437,Q01082,Q93009,O60826,O75844,O75175,Q9UIG0 46 +Dilated third ventricle 0.7654636536342494 1.579957687789593 0.114116556701816 1.0 0.4322426690598767 5 Q71SY5,O75787 2 +Breathing dysregulation 0.7992249115621097 1.5769460147945755 0.1148079474203558 1.0 0.4344564590084637 4 O75380 1 +Proximal muscle weakness in upper limbs 0.5802944678907547 1.5740460714132425 0.1154767987233866 1.0 0.4358031284221446 14 P50402,Q8WXH0,O95140,P02545,Q13642,P07196,P50336 7 +Abnormal sweat gland morphology 0.8209765512967013 1.5734747868962558 0.1156089219586116 1.0 0.4358031284221446 3 O75844 1 +Abnormal neuron morphology 0.4905174922844441 1.5733778776739642 0.1156313463243536 1.0 0.4358031284221446 28 Q99720,Q15165 2 +Pericardial effusion 0.7638436923710261 1.5733719346940562 0.1156327216149137 1.0 0.4358031284221446 5 P02545,Q14108,P49748 3 +Abnormality of the neck 0.3586232718037096 1.5719832354514702 0.1159544392218738 1.0 0.4366614903274294 186 Q99720,Q7RTS9,P02545,Q8N201,O00192,Q9UBM7,Q96EK5,P16278,A2RRP1,P11166,O60566,Q9UHX1,Q8WVQ1,Q96L58,Q9Y487,P15586,O95831,Q14739,Q9NXR1,Q13049,O00754,Q9Y3D3,O95155,Q15056,O15078,Q9Y448,P08236,O75431,O96028,P11274,Q9UQE7,Q15555,Q96RK4,O75569,P46783,Q01082,Q96HY6,O60826,O75844,Q9UIG0 40 +Restrictive cardiomyopathy 0.7333150233452301 1.5715232193803903 0.1160611653478 1.0 0.4367095023248801 2 Q969N2 1 +Tongue atrophy 0.7975143070832675 1.570195435097998 0.1163696512427976 1.0 0.4372039264306265 4 P07196,Q14331 2 +Abnormality of the musculature of the thigh 0.6651440865023204 1.5689835588444203 0.116651770027 1.0 0.4374254382280697 8 P50402,Q8WXH0,P02545,Q13642,P07196 5 +Insulin resistant diabetes mellitus 0.6866662695576803 1.5667015474018455 0.1171844689396608 1.0 0.4380983323914754 7 P02545,O75844,O75431 3 +Abnormality of the tarsal bones 0.4792871809402504 1.5661600768433128 0.1173111464559484 1.0 0.4381703352652964 30 Q9UHX1,Q8WVQ1,P98175,Q7RTS9,O75787,P02545,O75844 7 +Abnormality of the wrist 0.4539742461380621 1.5657738082453605 0.117401580012644 1.0 0.4381703352652964 35 P16278,Q8WVQ1,Q96L58,Q7RTS9,O95831,P02545,Q9H6K4,Q9NUQ7,O75844 9 +Macrogyria 0.6863743241645832 1.5654108686234625 0.1174866016226725 1.0 0.4381703352652964 7 O43505,Q9H9S5,Q15392,O14936 4 +Impacted tooth 0.8184693143230749 1.5636721378918392 0.117894584184738 1.0 0.439339320534465 3 O75844 1 +Breast aplasia 0.8175824175824181 1.5602035762753024 0.1187117807841056 1.0 0.4398558518677496 3 P02545,O75419 2 +Cerebral inclusion bodies 0.6000237709399733 1.5594926384538583 0.1188798255810323 1.0 0.4398558518677496 12 P05067,O15118,P61916 3 +Impaired tactile sensation 0.6393958064889849 1.5587381539513068 0.1190583674278911 1.0 0.4398558518677496 9 Q9NR77,Q5TAQ9,P39210 3 +Stroke 0.4530819126539713 1.5584896863829394 0.1191172109823264 1.0 0.4398558518677496 35 P03886,Q15056,Q96L58,Q9UIG0,P02545,P06280,O75844,P05067,P13807 9 +Flattened epiphysis 0.7944316574905177 1.5580244948285475 0.1192274416716778 1.0 0.4398558518677496 4 Q8WVQ1,O95831 2 +Abnormal thyroid morphology 0.4246129982532227 1.5512308720578918 0.120846366267862 1.0 0.4435800709283752 46 P20585,Q15437,P02545,P42892,P00813,Q96RR1,P48735 7 +Abnormality of the larynx 0.4102015698042178 1.5455163922697488 0.1222214070134077 1.0 0.4466409095824902 51 Q9UHX1,P07602,Q68CQ7,Q15165,Q14203,P02545,Q01082,Q96HY6,O00192,Q9UBM7 10 +Abnormality of neutrophil morphology 0.7207896153066078 1.5432642559379872 0.1227666724572458 1.0 0.4477996286568456 6 P35579,P41440 2 +Muscle spasm 0.402772779716866 1.542661336333731 0.1229129675016624 1.0 0.4479816156707651 60 Q9NR77,P49748,Q68CQ7,P23786,P00846,P53985,Q15165,Q14203,O75298,Q9H9S5,P07196,Q96RR1,P06280 13 +Blurred vision 0.6810285449761836 1.5417587873542973 0.1231322203705755 1.0 0.4483254643278156 7 P03886,P00846,O75306 3 +Focal dystonia 0.4906941220209313 1.5406846263496978 0.1233935602326106 1.0 0.4486775230054315 27 Q96L58,Q99720,O75569 3 +Eeg with focal spike waves 0.7258994781653338 1.5385279224589912 0.1239195867009554 1.0 0.4494891021858985 2 P11166 1 +Generalized myoclonic atonic seizure 0.7258994781653338 1.5385279224589912 0.1239195867009554 1.0 0.4494891021858985 2 P11166 1 +Abnormality of the cheek 0.3975894948503858 1.5381092988443394 0.1240218927503649 1.0 0.4494891021858985 64 Q9UHX1,O15078,Q96JJ3,Q9Y487,P52732,P02545,O75431,Q9Y366,O60826,O96028 10 +Progressive neurologic deterioration 0.5062551583910514 1.5376722523524475 0.124128771415207 1.0 0.4494891021858985 22 P16278,P20700,P07602,Q15046,Q7LG56,Q10713,P54802,O43681,P04062 9 +Muscle abnormality related to mitochondrial dysfunction 0.4343058453243061 1.534692693307406 0.1248593314803783 1.0 0.4515340960228155 42 P03886,O60313,Q9UBX3,O43676,P00846,Q7LG56,O75306,O75251,O75380,Q96RR1,Q9Y2R0,Q96CU9 12 +Fractures of the long bones 0.8108710923105267 1.5339396639253655 0.125044496950496 1.0 0.4518520819043196 3 Q13126 1 +Upper limb asymmetry 0.8106365369927158 1.533021249804387 0.1252706192362038 1.0 0.4520875566764902 3 Q15555 1 +Abnormal peripheral nervous system morphology 0.3509394116818442 1.5284611648633413 0.1263980785878369 1.0 0.4547934534114798 174 Q99720,Q71SY5,P02545,P06753,P39210,Q9HC21,Q00796,Q9NR77,O60313,Q9UHX1,Q7Z406,Q9BQT8,Q14203,O95831,Q9BPX6,Q96RR1,Q13049,Q6DKK2,P00403,P03886,P20700,P07602,Q15046,Q8IV08,P00846,Q7LG56,Q9Y4W6,Q9H9S5,P51798,P41440,P17480,P31749,Q14331,Q01082,Q5TAQ9,O43681,P07196,Q9GZY8 38 +Abnormality of skull ossification 0.572065000034663 1.5284288713578589 0.126406091086874 1.0 0.4547934534114798 14 O75718,Q14739,P02545,P54802,O75844 5 +Abnormality of upper limb epiphysis morphology 0.5431108025644041 1.5282692779784164 0.1264456943851155 1.0 0.4547934534114798 16 O96028,Q7RTS9 2 +Areflexia of lower limbs 0.5023850085592523 1.52682109024255 0.1268055057240282 1.0 0.4554597791060084 23 Q9NR77,O60313,O75787,Q7LG56,Q96RR1,P07196 6 +Symptomatic seizures 0.6776055801122913 1.526596045804309 0.1268614909038865 1.0 0.4554597791060084 7 P53985,Q13423 2 +Palpebral edema 0.7161302987615873 1.5235957984584203 0.1276097133874638 1.0 0.456659307708111 6 Q01082,Q9Y448 2 +Conjunctival hamartoma 0.8076586625647904 1.5213583579865972 0.1281699328141941 1.0 0.457103359775564 3 Q15437 1 +Bone cyst 0.8076586625647904 1.5213583579865972 0.1281699328141941 1.0 0.457103359775564 3 Q15437 1 +Follicular thyroid carcinoma 0.8076586625647904 1.5213583579865972 0.1281699328141941 1.0 0.457103359775564 3 Q15437 1 +Spastic diplegia 0.4922626928998725 1.5204788065258117 0.1283906813257151 1.0 0.4573562247698162 26 Q99720 1 +Calf muscle pseudohypertrophy 0.8073863849771379 1.5202917185369096 0.1284376744834539 1.0 0.4573562247698162 3 Q13049 1 +Cupped ear 0.5702071991127698 1.5181111379553558 0.1289863838195406 1.0 0.4579136545287676 14 Q15392 1 +Abnormal 3rd finger morphology 0.7843330342540765 1.5181032422437135 0.1289883739569952 1.0 0.4579136545287676 4 Q71SY5 1 +Abnormal delivery 0.4958233069418871 1.5163672840572529 0.1294265068170144 1.0 0.4584184277276417 25 Q9Y487,O75718,P02545,Q01082,P06753,Q9UBM7,O75844 7 +Decreased cervical spine mobility 0.720406481735782 1.5140622396349863 0.1300100545624753 1.0 0.4590856561943944 2 Q9H9S5 1 +Abnormality of the tongue muscle 0.720406481735782 1.5140622396349863 0.1300100545624753 1.0 0.4590856561943944 2 Q9H9S5 1 +Abnormal muscle fiber alpha dystroglycan 0.720406481735782 1.5140622396349863 0.1300100545624753 1.0 0.4590856561943944 2 Q9H9S5 1 +Fusion of the cerebellar hemispheres 0.720406481735782 1.5140622396349863 0.1300100545624753 1.0 0.4590856561943944 2 Q9H9S5 1 +Generalized osteosclerosis 0.8035714285714293 1.5053423307226153 0.1322360873836241 1.0 0.465884077385672 3 Q15392,P51798 2 +Microcornea 0.4482772564040311 1.504565193911875 0.1324359004330044 1.0 0.4662345676607361 34 Q9UQE7,Q15555,Q8NCH0,O15078,Q96L58,O43505,P52732,Q71SY5,Q8NAT1,Q9H9S5 10 +Fatty replacement of skeletal muscle 0.6276679885482574 1.5024833935417738 0.1329723135393101 1.0 0.4674147814048217 9 Q8NFF5,Q9H9S5,Q7Z406 3 +Hyporeflexia of lower limbs 0.5965218580815157 1.500219852187595 0.1335574624740108 1.0 0.468762483471849 11 Q9NR77,P02545 2 +Hypochromic anemia 0.5885133212722046 1.499079258592246 0.1338530717072323 1.0 0.4694454522441576 12 O75027 1 +Recurrent sinopulmonary infections 0.7092000826353979 1.4943026010658669 0.1350965456088624 1.0 0.4719741998236061 6 Q9Y487 1 +Acute phase response 0.4950942257746984 1.4935626232072972 0.135289974820761 1.0 0.4719741998236061 24 P41440,P14174 2 +Saccadic oscillation 0.8002747252747258 1.492417433661677 0.1355897475284084 1.0 0.4719741998236061 3 Q5THJ4,P51798 2 +Aortic valve calcification 0.800274725274726 1.492417433661677 0.1355897475284084 1.0 0.4719741998236061 3 P02545,O75844 2 +Centrocecal scotoma 0.7085694980270671 1.4916350112004997 0.1357948546487219 1.0 0.4723343484675232 6 P03886,P00846,O75306 3 +Pseudobulbar paralysis 0.6480015756796963 1.4902141809952982 0.1361679288406709 1.0 0.4732777601515318 8 P20700,Q14203,Q15233 3 +Abnormal circulating methionine concentration 0.7078825737062234 1.4887286842533158 0.136558828416146 1.0 0.4737991909712797 6 Q99707,Q6PGP7,P16930,P55263 4 +Pancreatic islet cell hyperplasia 0.7992712133365876 1.488482001595314 0.1366238252424176 1.0 0.4737991909712797 3 P53985 1 +Abnormality of limb epiphysis morphology 0.4575565059015888 1.4841974149567814 0.1377565554011441 1.0 0.4758059915088489 32 Q8WVQ1,Q96L58,Q7RTS9,O95831,Q9Y366,O96028 6 +Abnormal morphology of the conjunctival vasculature 0.6680263197518548 1.4840922321012149 0.1377844537089936 1.0 0.4758059915088489 7 P10619,P06280 2 +Talipes equinovarus 0.3810680725782028 1.483659391005513 0.1378993047072363 1.0 0.4758059915088489 93 Q9NR77,O00754,Q8NCH0,O00192,P98175,Q8WVQ1,Q9HD42,Q9Y487,Q96L58,Q7RTS9,Q8TD16,Q15392,Q01082,P06753,Q6ZXV5,O75530,O96028,P32929 18 +Abnormal left ventricle morphology 0.4439284927429863 1.4835843193776288 0.1379192318834559 1.0 0.4758059915088489 35 P03886,O60566,O75787,P00403,Q7LG56,Q9H9S5,P10253,O75431,P78536,Q96RR1,P06280,P13807 12 +Anemia of inadequate production 0.3820585324147649 1.4827830453650734 0.1381320620991177 1.0 0.4758604651826785 71 P22830,P41440,O75027,Q15437 4 +Progressive psychomotor deterioration 0.6462149542526943 1.4819837138300005 0.13834462846176 1.0 0.4758604651826785 8 P07602,O43681 2 +Abnormality of visual evoked potentials 0.4956861605308717 1.4814605505004597 0.1384838897766436 1.0 0.4759871566509341 23 O75503,P07602,O43681 3 +Abnormality of the thymus 0.5200076406521824 1.479963746790936 0.1388829218421599 1.0 0.4766535729693626 17 O00192,Q6PGP7,P00813 3 +Xerostomia 0.5491866068309346 1.478442588787913 0.1392893531474284 1.0 0.4773433805870942 15 P55011,Q68CQ7,P35637,Q15165,Q14203,Q14739,Q92804 7 +Adult onset 0.3819830777119132 1.4775600320349622 0.1395255788807596 1.0 0.4777962332440457 73 P20700,P07602,O15118,Q8IV08,P02545,Q71SY5,Q9Y4G8,P31751,Q9Y6M1,Q9NWW5,Q96RR1,P41440,Q14566 13 +Broad ribs 0.7402215097785965 1.477081113277515 0.1396538956024433 1.0 0.4777962332440457 5 Q7RTS9 1 +Pruritus 0.4925019465071575 1.4757874762776286 0.1400009538153255 1.0 0.4783709061616306 24 P22830,P00813 2 +Abnormality of the auditory canal 0.4968152875296786 1.4744617933311108 0.1403572974126228 1.0 0.4789650067550127 22 Q9UQE7,P55011,O75419,Q9H9S5,P78536,O96028 6 +Intestinal hypoplasia 0.7730483412896225 1.4734120207271455 0.1406399709207997 1.0 0.4789650067550127 4 O75844 1 +Widow s peak 0.795406404458205 1.4733209512922616 0.1406645139159348 1.0 0.4789650067550127 3 O15344 1 +Onion bulb formation 0.6440760144397646 1.4721253971822996 0.140987018383883 1.0 0.4789650067550127 8 Q9NR77,P07196 2 +Megalocornea 0.5479250033617032 1.4711731518493014 0.1412442959696145 1.0 0.4790965280078822 15 Q15056,Q9H9S5,O96028,Q96EK5,Q9UIG0 5 +Homocystinuria 0.771696470960701 1.4680530294570309 0.1420898189165163 1.0 0.480561418125947 4 Q9NUN5 1 +Intestinal malrotation 0.4608132987998487 1.4667477003002412 0.1424447016224952 1.0 0.4814112934107166 31 P55011,Q8NCH0,O60826,Q15392,Q14739,O00192,Q9UBM7,O96028 8 +Abnormal circulating ige level 0.663755290372022 1.4651100110509596 0.1428909057818632 1.0 0.4820396165728663 7 P00813 1 +Abnormal sternal ossification 0.7708978778060533 1.4648868256699354 0.1429517977450112 1.0 0.4820396165728663 4 O96028 1 +Calvarial skull defect 0.6424726468580408 1.4647321554747232 0.1429940082998246 1.0 0.4820396165728663 8 O96028,Q14739 2 +Left ventricular systolic dysfunction 0.6422191701285254 1.463563097025805 0.1433133617667223 1.0 0.4824235220739828 8 P02545,Q96RR1,O75844,P49748 4 +Progressive spastic quadriplegia 0.6421618486543896 1.463298715281322 0.1433856591331339 1.0 0.4824235220739828 8 P07602,O43681 2 +Congenital muscular dystrophy 0.7925750876312886 1.4622097622823869 0.1436837372783179 1.0 0.4824235220739828 3 P02545 1 +Spinal muscular atrophy 0.5732096658642707 1.461143950525853 0.1439759409559913 1.0 0.482724529309157 13 Q99720 1 +Retinal telangiectasia 0.6412853491918307 1.4592556241588217 0.1444947642243343 1.0 0.4834176885172656 8 P03886,P00846,O75306 3 +Nephrotic syndrome 0.4425249168414131 1.4578297324084908 0.1448874807556917 1.0 0.4840345960256644 34 Q14108,Q8NCH0,O15078,P51809,Q03252,Q8N1F7,P00813,Q13049,P06280 9 +Abnormality of glycolipid metabolism 0.6615799607125273 1.455434992403498 0.1455488748968969 1.0 0.4849386407395245 7 P07602,O43681 2 +Limb undergrowth 0.3979024599376518 1.4553387212805589 0.1455755119069586 1.0 0.4849386407395245 56 O00116,A2RRP1,Q9UQE7,Q9UHX1,P98175,Q7RTS9,O15287,Q15392,O75718,Q14739,P48735,Q96HY6,Q9Y366,Q9UBM7,Q969N2 15 +Nemaline bodies 0.7683107784257901 1.4546273299284036 0.1457724606627191 1.0 0.4852468658306989 4 O43676,P07196 2 +Ragged red muscle fibers 0.4953314850622465 1.4514788460361532 0.1466465685248175 1.0 0.4871097955216775 21 P31040,P03886,Q70HW3,Q9H2D1,P00846,Q7LG56,O95831,Q96RR1,P00403 9 +Patchy changes of bone mineral density 0.7893507810930702 1.449552172147282 0.1471834415522639 1.0 0.4879941797126899 3 Q13126 1 +Abnormal circulating citrulline concentration 0.6985946470163933 1.4493930283359584 0.147227854520592 1.0 0.4879941797126899 6 P03886 1 +Slow saccadic eye movements 0.5935405430994769 1.448410828776587 0.1475021880967761 1.0 0.4884674935901517 10 Q9Y4W6,Q8IV08 2 +Vocal cord paralysis 0.4995236328411631 1.4481293360622982 0.1475808825049651 1.0 0.4884674935901517 18 Q9NR77,P31040,P50402,Q8WXH0,Q14203,O95140,P02545,P43243 8 +Proximal upper limb amyotrophy 0.6979251875653563 1.4465551025024863 0.1480215685979367 1.0 0.4889283370268882 6 P50402,Q8WXH0,Q13642,P02545 4 +Abnormality of the musculature of the upper arm 0.6979251875653563 1.4465551025024863 0.1480215685979367 1.0 0.4889283370268882 6 P50402,Q8WXH0,Q13642,P02545 4 +Scapular winging 0.4857372492898065 1.4463831393653217 0.1480697682751794 1.0 0.4889283370268882 25 Q9Y487,Q8TD16,Q14331,P02545,P06753,P07196 6 +Abnormal scapula morphology 0.3983545170961217 1.4457540937207047 0.1482461861138122 1.0 0.4889283370268882 54 Q9Y487,Q7RTS9,Q8TD16,P46783,Q14331,Q14739,P02545,P06753,P07196 9 +Bradycardia 0.5858547493236494 1.445309713716176 0.1483709106352038 1.0 0.4889926395190014 11 P02545,O43772 2 +Rhabdomyolysis 0.5570350825345883 1.4447639842643945 0.1485241906263974 1.0 0.4891508957057894 14 P23786,Q86VD7,O43772 3 +Prominent superficial blood vessels 0.5779536299198416 1.443454639703749 0.1488924416474346 1.0 0.4900164138354311 12 Q9Y487,O75844 2 +Abnormal brainstem morphology 0.375482673322659 1.44261464776779 0.1491290547856918 1.0 0.4901009318169094 99 P07942,Q9HD42,Q96N67,Q5KU26,Q96EK5,O60313,O43676,O95831,O75251,Q6ZXV5,Q9NXR1,Q96RR1,Q13813,O14936,P03886,P20700,O15078,O43505,P11177,Q9H9S5,Q96CU9,Q9Y3C6,P31749,O75306,O75380 25 +Neurodegeneration 0.4675226764645904 1.4404713879567843 0.1497340792794101 1.0 0.4916917792074691 29 Q68CQ7,P35637,Q15165,Q14203,Q5JTZ9,Q01082,P08236,Q8NHS3,Q92804,P17480,Q6DKK2 11 +Echolalia 0.5919026275073926 1.440150803438108 0.1498247384027924 1.0 0.4916917792074691 10 Q9UHX1,O95714,O75787,Q01082,Q9UJS0 5 +Mitral stenosis 0.7641085434045999 1.437955520421829 0.1504466749758468 1.0 0.4926498533985542 4 P02545,O75844 2 +Persistence of primary teeth 0.6957565011135969 1.4373594448525429 0.1506158859996567 1.0 0.4926498533985542 6 O75844 1 +Cyanosis 0.4960346502640437 1.4343926468092416 0.1514602448459581 1.0 0.4932275807982952 19 P04066,P98175,O43772,P02545,O75844 5 +Acquired abnormal hair pattern 0.6939132518177525 1.4295409997372448 0.1528487995653349 1.0 0.4965662751532375 6 P02545,O75844 2 +Fragile nails 0.5897229085631222 1.4291528567902292 0.1529603041853495 1.0 0.4965662751532375 10 Q9Y487,Q13555 2 +Abnormality of the radioulnar joints 0.7841038638494349 1.4289459206873771 0.1530197774950368 1.0 0.4965662751532375 3 Q96L58 1 +Radioulnar dislocation 0.7841038638494349 1.4289459206873771 0.1530197774950368 1.0 0.4965662751532375 3 Q96L58 1 +Vertebral fusion 0.566942594384224 1.4272825116504848 0.1534984793982523 1.0 0.4974249886776001 13 O96028,Q9UHX1 2 +Abnormal arterial physiology 0.4548230574404308 1.4207149036270408 0.155399658028275 1.0 0.5028845479508315 31 Q15056,Q9NZ08,Q14739,P02545,P06280,O75844,P05067 7 +Diffuse cerebral atrophy 0.4949056599051662 1.4183200921084442 0.1560973332774331 1.0 0.5040891645171868 18 Q06787,Q9NVC6,P16278,P07602,O75787,Q10713,Q96T60,O14936 8 +Ventricular preexcitation 0.6100511128657398 1.4176333179766218 0.1562978474965899 1.0 0.5043861786921204 9 P03886,P00846,P10253,O75306 4 +Retinal vascular tortuosity 0.4914697171147908 1.4144929470780303 0.1572172167633021 1.0 0.5057527991620466 20 P03886,Q15056,P00846,O75306,O00192 5 +Absence of pubertal development 0.7248802938689547 1.4143283949915888 0.1572655035053061 1.0 0.5057527991620466 5 O75844 1 +Poor speech 0.3746001891830093 1.41239794708027 0.1578328206066417 1.0 0.5068756858044672 95 Q05639,Q01105,P55263,Q9HD42,Q7RTS9,Q8N3U4,Q96N67,Q71SY5,Q9BRT2,Q9Y487,Q10713,P55011,O95155,Q15233,Q9UBB6,Q9H9S5,P08236,Q96CU9,P35222,Q96N66,Q14139,Q9UQE7,O00584,Q6PJT7,Q9NUQ7,O60826 26 +Perseveration 0.6518216602262707 1.4119804997044594 0.1579557030242344 1.0 0.506919994443106 7 Q93009,Q15233,P61916 3 +Tinnitus 0.5231965656600054 1.4093635473876762 0.1587276970664395 1.0 0.5083443199639864 16 Q9NR77 1 +Intestinal polyp 0.4870526129744393 1.4088396858219563 0.1588825773473916 1.0 0.5084899014692348 22 P20585,O60566,P35222,Q15437,P42892,P31749 6 +Broad palm 0.6508453892325237 1.4076286121934087 0.1592410704928215 1.0 0.5092864794082187 7 Q7RTS9 1 +Subacute progressive viral hepatitis 0.755812409468624 1.4050182152190922 0.1600158618210363 1.0 0.5103594439823994 4 P11717,Q9NWH9 2 +Viral hepatitis 0.755812409468624 1.4050182152190922 0.1600158618210363 1.0 0.5103594439823994 4 P11717,Q9NWH9 2 +Spastic tetraparesis 0.4672805064291809 1.404364348397252 0.1602103815438362 1.0 0.5106293847971242 28 Q7RTS9,P07602 2 +Abnormality of the pharynx 0.3924502858543987 1.4001183725547326 0.1614778741594074 1.0 0.5134320975873938 56 P16278,O15344,Q7RTS9,P15586,Q86YV9,P08236,P54802,O00192,P00813,P29372 10 +Cutaneous syndactyly 0.6063103930641799 1.3995698463915032 0.1616421688767715 1.0 0.5134320975873938 9 P27635,P98175,Q9H4L7,Q9Y2U8,Q9Y619 5 +Abnormality of the musculature of the limbs 0.3422163893637176 1.3960754470544252 0.1626917766596405 1.0 0.5164130369790639 173 Q99720,Q7RTS9,Q8TD16,P02545,P06753,O75298,Q13126,P39210,Q9HC21,Q00796,Q9NR77,O60313,Q8N0X7,Q9Y487,Q7Z406,Q9BQT8,Q14203,Q14739,Q96RR1,Q13049,P50336,P07602,Q15046,P00846,Q7LG56,Q9Y4W6,Q96F07,Q9H9S5,P17480,P31749,P46783,Q14331,Q8NAT1,P42356,P07196 35 +Difficulty running 0.5480461585112767 1.394533939468697 0.1631564279987181 1.0 0.5169982305913028 14 Q9BPX6,Q9H9S5,Q8TD16,P07196 4 +Lipodystrophy 0.4294249799439401 1.3943567562507773 0.1632098997799529 1.0 0.5169982305913028 37 P04066,Q9Y487,P28070,Q03252,P02545,O75431,P09493,O75844 8 +Mitochondrial inheritance 0.6467617069837357 1.389416887413232 0.1647060180257891 1.0 0.520871920707802 7 P03886 1 +Abnormal conjunctiva morphology 0.4606212478156852 1.3892095490945322 0.1647690388294531 1.0 0.520871920707802 29 P04066,P02786,P28070,Q9NZ08,Q15437,P10619,P06280 7 +Encephalocele 0.490235506371917 1.3881246653470267 0.1650990870084037 1.0 0.5213865842268639 18 Q15051,P07942,O15078,O43505,Q9H9S5,Q6ZXV5 6 +Decreased methylcobalamin 0.7515126845085107 1.3879369633541372 0.1651562410118234 1.0 0.5213865842268639 4 Q9NUN5 1 +Mitochondrial myopathy 0.4320349430417114 1.385801693631441 0.1658074651017407 1.0 0.5228669492016701 35 P03886,O60313,O43676,P00846,Q7LG56,O75306,O75251,O75380,Q96RR1,Q96CU9 10 +Functional motor deficit 0.3389602902184045 1.3856617902283606 0.1658502008012183 1.0 0.5228669492016701 167 Q99720,Q7RTS9,Q8TD16,Q71SY5,P06753,O75298,O14773,Q00796,Q9NR77,O75787,Q9BPX6,Q96RR1,P03886,P20700,P07602,P23786,P00846,Q96F07,Q9H9S5,Q9Y2R0,O43681,Q8NFF5,P07196,Q9GZY8 24 +Vascular neoplasm 0.4283424978534853 1.3852619014051608 0.1659723988350498 1.0 0.5228974490755776 37 Q9UHX1,O60826,Q15437,O96028,Q9UBM7,P10619 6 +Exaggerated cupid s bow 0.6456845245330697 1.3846109753580182 0.1661714536485021 1.0 0.5231698815071745 7 Q71SY5,Q969N2,Q96KP1 3 +Eeg with spike wave complexes 0.5188926820013151 1.3835605771479056 0.1664930465904617 1.0 0.5234451273738947 16 O75503,P11166,Q969N2,Q14108 4 +Abdominal pain 0.3737706914813628 1.3832252054378935 0.1665958234478111 1.0 0.5234451273738947 89 Q14108,Q70HW3,Q15056,Q13423,P23786,Q9NZ08,Q9NWH9,P14174,O43707,Q01082,Q14566,P42892,Q8N1F7,Q969N2,P06280,P50336,O14936 17 +Abnormality of pelvic girdle bone morphology 0.3378719017358936 1.3824058917435198 0.1668471080786071 1.0 0.5234451273738947 165 Q8IWS0,Q7RTS9,Q8IZA0,Q8N3U4,Q8TD16,P02545,P06753,Q8N3R9,Q9Y366,Q9UBM7,Q9Y619,P16278,Q9UHX1,Q8WVQ1,Q96L58,Q9Y487,O75718,O95831,Q14739,P00813,Q5H8A4,O00754,P55011,O95155,Q15056,Q03252,Q9H9S5,P08236,O75431,P51798,O75530,O96028,O15287,P31749,Q9UQE7,O15228,Q9NQT5,Q9NUQ7,Q93009,Q96HY6,O60826,O75844,O75175,Q9UIG0 44 +Focal white matter lesions 0.6026996366836616 1.3821204265993638 0.1669347275162711 1.0 0.5234451273738947 9 O00584,Q9H2P0,Q7LG56,Q9P0J1,Q96RR1,O00443 6 +Thyroiditis 0.5731003814077297 1.3794417571644562 0.1677585921008035 1.0 0.5256737542093285 11 P00813 1 +Skin tags 0.4839596091591023 1.3757398054167405 0.1689022035118497 1.0 0.5267708320265541 21 O96028,O60826,Q9UHX1,P31749 4 +Distal sensory impairment 0.4052312707548973 1.371928328636722 0.1700857505368189 1.0 0.5293242340923042 46 Q9NR77,O95831,P02545,Q71SY5,P39210,P54802,Q96RR1,P07196 8 +Furrowed tongue 0.5783426591849382 1.3716367569266126 0.1701765452407795 1.0 0.5293242340923042 10 Q71SY5,Q15437 2 +Aplasia hypoplasia of the nipples 0.4874695567027615 1.370219216352359 0.1706184814761115 1.0 0.5296123670534723 18 O96028,Q9UQE7,O60826,P10586 4 +Confusion 0.4861773815147944 1.370031306940752 0.1706771290979487 1.0 0.5296123670534723 19 O00754,P11166,O96008,Q9NZ08,P05067 5 +Abnormal brainstem mri signal intensity 0.4746887844013464 1.3694168514396003 0.1708690096677578 1.0 0.5296123670534723 25 P03886,O43676,O95831,O75380,Q96CU9 5 +Corpus callosum atrophy 0.5435532451403282 1.369380443989624 0.1708803839600019 1.0 0.5296123670534723 14 O75503,P20700,O00754 3 +Ventricular escape rhythm 0.713869970265042 1.3692132127789762 0.1709326370535653 1.0 0.5296123670534723 5 P50402,Q8WXH0,P02545 3 +Clonic seizure 0.6422199512290804 1.3691480812445973 0.17095299130196 1.0 0.5296123670534723 7 Q01082,P07602 2 +Severe muscular hypotonia 0.431512398327373 1.3680498368874636 0.1712964769333056 1.0 0.5296790155979504 34 Q01105,P80404,Q8TD16,O43505,O95831,P02545,P06753,Q9H9S5,O75380,Q5H8A4,Q9NWS8,Q9GZY8 12 +Abnormality of the umbilical cord 0.599776727649235 1.367986014828427 0.1713164537214804 1.0 0.5296790155979504 9 O60826,O75844 2 +Delayed menarche 0.6792268873319636 1.3671677850364612 0.1715727203959518 1.0 0.5301186380850985 6 O75844 1 +Prenatal maternal abnormality 0.5541639270453441 1.3580566764753066 0.174445700787575 1.0 0.5375657636338602 13 P02545,Q01082,O43772 3 +Hypotension 0.4649869962688798 1.3563353407475287 0.1749924958652475 1.0 0.5388933918394999 27 P20700,P07602,Q13423,O43772,O43681 5 +Abnormality of carpal bone ossification 0.710456001081369 1.3552143292415966 0.175349280621629 1.0 0.5389118711167737 5 Q96L58,Q8WVQ1 2 +Skin pit 0.5606774489998009 1.3520965255092865 0.1763444386802599 1.0 0.5405492127619842 12 O96028 1 +Slow pupillary light response 0.7091381660523551 1.349809543824892 0.1770770827191201 1.0 0.5420798441342235 5 Q9NR77 1 +Abnormal pupillary light reflex 0.7091381660523551 1.349809543824892 0.1770770827191201 1.0 0.5420798441342235 5 Q9NR77 1 +Multifactorial inheritance 0.5522259572957823 1.347539245097103 0.1778066227289805 1.0 0.5429937303349498 13 P11274,P42892 2 +Iris coloboma 0.4176312207670543 1.346583243138295 0.1781144939686934 1.0 0.5429937303349498 40 Q9UHX1,O60826,O15078,Q8WXW3,O43505,Q8NAT1,Q01082,Q9H9S5,O96028,Q9UBM7,Q96EK5 11 +Aplasia hypoplasia involving the metacarpal bones 0.4592979495595609 1.3459587371116493 0.1783158242703193 1.0 0.5429937303349498 28 Q8WVQ1,Q9NX62,Q96L58,Q7RTS9,Q14739,Q9Y448,Q9Y366 7 +Hypoplastic pubic rami 0.7080784346402256 1.345462923791619 0.1784757867556465 1.0 0.5429937303349498 5 O96028 1 +Rib segmentation abnormalities 0.7080784346402256 1.345462923791619 0.1784757867556465 1.0 0.5429937303349498 5 O96028 1 +Abnormality of abdominal situs 0.7080784346402256 1.345462923791619 0.1784757867556465 1.0 0.5429937303349498 5 O96028 1 +Edema of the dorsum of hands 0.6825048063718716 1.344889425887825 0.1786609454878713 1.0 0.5429937303349498 2 Q9Y5S9 1 +Edema of the dorsum of feet 0.6825048063718716 1.344889425887825 0.1786609454878713 1.0 0.5429937303349498 2 Q9Y5S9 1 +Teratoma 0.7625803391263763 1.344339746195324 0.1788385483944576 1.0 0.5431782577706175 3 P20585 1 +Urinary incontinence 0.4075975876911236 1.343146710069623 0.1792244731692791 1.0 0.5434286296246463 44 Q99720,P07602,O43681 3 +Atrophy degeneration involving the spinal cord 0.6161498342624477 1.343001526636448 0.1792714795147989 1.0 0.5434286296246463 8 Q96RR1,P07196 2 +Heart block 0.4772902806145089 1.343000513881467 0.179271807448802 1.0 0.5434286296246463 22 P49748,P23786,O43772,P02545,P06280 5 +Abnormality of the autonomic nervous system 0.3833298328015955 1.340427377966507 0.1801064398135754 1.0 0.5451583742062931 60 P20700,P07602,O15078,Q96RR1,P42892,O43681,O00192,Q9UBM7,P41440,Q96EK5,P06280,P50336 12 +Enlarged ovaries 0.7067508077839504 1.3400170421134752 0.1802398044287738 1.0 0.5451583742062931 5 Q15437 1 +Vertical supranuclear gaze palsy 0.5582886806720211 1.3394353015983425 0.1804290035569784 1.0 0.5451583742062931 12 Q96RR1,Q969N2,O15118,P61916 4 +Bilateral sensorineural hearing impairment 0.4538274854658028 1.3386318480566464 0.1806905527998443 1.0 0.5455938913975807 29 P03886,P07602,Q7Z406,Q01082,O43681,Q96RR1 6 +Periodic paralysis 0.6797583081570953 1.3326211631292952 0.1826561565553537 1.0 0.5506313137096684 2 P16930 1 +Progressive external ophthalmoplegia 0.5369801097724705 1.332530878549857 0.1826858016271035 1.0 0.5506313137096684 14 P03886,Q96RR1,O60313,Q7LG56 4 +Impaired social interactions 0.3880456533825768 1.3323568580633052 0.1827429515675582 1.0 0.5506313137096684 52 P03886,P11166,Q9UHX1,O43676,Q96N67,O75251,Q01082,O75380,Q96RR1,Q96CU9,Q9GZY8 11 +Wide intermamillary distance 0.471547069513524 1.331482564208075 0.1830302783410031 1.0 0.5506313137096684 24 Q15555,P23786,O14678,Q9Y448,O75530,Q9UBM7 6 +Elevated serum acid phosphatase 0.7371901454593522 1.331002173111826 0.1831882958887771 1.0 0.5506313137096684 4 P07602 1 +Osteopenia 0.3696013434746842 1.3302451692814317 0.1834375062345441 1.0 0.5507172347651056 76 O00754,Q14108,P07602,Q96L58,Q9Y487,O75844,O75718,P02545,Q9Y448,Q13126,O75431,O75530,Q969N2 13 +Osteolytic defects of the distal phalanges of the hand 0.7369872621028775 1.3301953941374625 0.1834539013162004 1.0 0.5507172347651056 4 O75844,O75431 2 +Hypoplasia of the frontal lobes 0.5906096104271652 1.3236094142484451 0.1856327969475879 1.0 0.5543750595790421 9 Q9UBM7,P35606 2 +Left ventricular hypertrophy 0.4418885284035558 1.32098406728357 0.1865066767762311 1.0 0.5561491353456541 31 P03886,O75787,P00403,Q7LG56,Q9H9S5,P10253,O75431,P78536,Q96RR1,P06280,P13807 11 +Urogenital sinus anomaly 0.7564076574464805 1.3200649861029778 0.1868133217419711 1.0 0.5561491353456541 3 P51809 1 +Decreased number of large peripheral myelinated nerve fibers 0.6681226130266733 1.3199342748456224 0.1868569628645318 1.0 0.5561491353456541 6 P07196,Q7LG56 2 +Hypermethioninemia 0.7018525222620334 1.319920616176666 0.1868615235768664 1.0 0.5561491353456541 5 Q6PGP7,P16930,P55263 3 +Abnormality of the endometrium 0.5679465176138698 1.3189727199224774 0.1871782327696585 1.0 0.5561491353456541 10 P20585,Q15437 2 +Abnormality of the synovia 0.3672555481419935 1.3181669521469987 0.1874477658263933 1.0 0.5562386767530331 94 Q7RTS9,Q8TD16,P02545,P06753,Q9Y366,Q9UBM7,P16278,Q9UHX1,Q8WVQ1,Q96L58,Q9Y487,O75718,P55011,Q03252,Q9H9S5,P08236,O96028,Q9UQE7,O75844 19 +Erlenmeyer flask deformity of the femurs 0.7336330685769409 1.3168565936079983 0.1878866985432674 1.0 0.5567065131415984 4 P07602,P51798 2 +Lacticaciduria 0.6102301946483952 1.315552701967453 0.1883242174862476 1.0 0.5567065131415984 8 P03886 1 +Abnormal circulating tyrosine concentration 0.7546703296703305 1.313232814989555 0.1891045096323176 1.0 0.5583028311698729 3 Q9NVS9,P16930 2 +Abnormal nephron morphology 0.3698215198959731 1.3096899767818244 0.1903007357352431 1.0 0.5607657063802629 69 P03886,Q14108,Q15056,P23786,P00846,Q9NZ08,O75306,O43707,P02545,Q03252,O75431,Q8N1F7,P00813,Q9NQH7,P06280 15 +Progressive hearing impairment 0.5064802776226686 1.3089745491993647 0.1905429720014488 1.0 0.5611236951145329 16 P03886,Q96RR1,O60313,Q7Z406 4 +Hemangiomatosis 0.7529183199647174 1.3063430795494382 0.1914359132933367 1.0 0.5626835478014774 3 P48735 1 +Lymphangioma 0.7529183199647174 1.3063430795494382 0.1914359132933367 1.0 0.5626835478014774 3 P48735 1 +Visceral angiomatosis 0.7529183199647174 1.3063430795494382 0.1914359132933367 1.0 0.5626835478014774 3 P48735 1 +Posterior pituitary dysgenesis 0.752205066697752 1.303538296878996 0.1923910506064197 1.0 0.5647765080025473 3 Q9UHX1 1 +Hip pain 0.6977674201381512 1.303156858361499 0.192521215345953 1.0 0.5648018230509114 5 O75844 1 +Hypoplastic vertebral bodies 0.6638113448892226 1.301583928908906 0.1930586565956347 1.0 0.5656914404318263 6 P16278 1 +Agitation 0.4231784682150615 1.2998854362961747 0.19364023733647 1.0 0.5656914404318263 34 Q68CQ7,Q15165,P52732,Q14203,Q01082,P42892,P05067 7 +Axillary pterygium 0.6723427629771995 1.2995025624598888 0.1937715146432244 1.0 0.5656914404318263 2 O15111 1 +Aplasia cutis congenita over the scalp vertex 0.6723427629771995 1.2995025624598888 0.1937715146432244 1.0 0.5656914404318263 2 Q14692 1 +Congenital localized absence of skin 0.6723427629771995 1.2995025624598888 0.1937715146432244 1.0 0.5656914404318263 2 Q14692 1 +Acral blistering 0.6723427629771994 1.2995025624598875 0.1937715146432248 1.0 0.5656914404318263 2 Q9H4L7 1 +Blistering by anatomical location 0.6723427629771994 1.2995025624598875 0.1937715146432248 1.0 0.5656914404318263 2 Q9H4L7 1 +Pelvic girdle muscle weakness 0.5640923290134665 1.2994244197918594 0.193798315723578 1.0 0.5656914404318263 10 Q9H9S5,Q13049 2 +Episodic vomiting 0.5429795597337361 1.2973013886027511 0.194527506805872 1.0 0.5667519273522805 13 P03886,P22695,P49748,P00846,P00403 5 +Papilloma 0.5571043374361059 1.2965695969213316 0.1947793190411324 1.0 0.5667748876544412 11 P20585,P16615,Q15437 3 +Temperature instability 0.6059800300640936 1.2958335635818092 0.1950328319667476 1.0 0.5671574281285833 8 P20700,P07602,Q8N3U4,Q9HC21 4 +Recurrent hand flapping 0.7282220390217113 1.2953368110138486 0.1952040658253735 1.0 0.5673003714137028 4 P55795,Q9UNW9,O95714 3 +Cholecystitis 0.6056546052786165 1.2943233758600523 0.195553745378386 1.0 0.5675984412543312 8 P07602 1 +Optic nerve hypoplasia 0.4732434485855926 1.29401747997851 0.1956593830334112 1.0 0.5675984412543312 20 Q9UHX1,Q9Y448,Q9H9S5,Q9NXR1,P07196,O14936 6 +Jerky head movements 0.7495788020448367 1.2932112817877326 0.1959379947704016 1.0 0.5675984412543312 3 P11166 1 +Hypolipidemia 0.6706948640483337 1.2921446623360793 0.1963070513795135 1.0 0.5675984412543312 2 Q9Y6B6 1 +Hypotriglyceridemia 0.6706948640483337 1.2921446623360793 0.1963070513795135 1.0 0.5675984412543312 2 Q9Y6B6 1 +Mixed demyelinating and axonal polyneuropathy 0.6943148338994203 1.2889870124407072 0.1974026017741195 1.0 0.5697701182884058 5 P03886 1 +Dysgenesis of the cerebellar vermis 0.6698709145839009 1.288466033523344 0.1975837852514119 1.0 0.5699390751479275 2 Q10713 1 +Abnormality of the foot musculature 0.6695962647624233 1.2872398747688676 0.1980106928831686 1.0 0.5706781628924155 2 O14979 1 +Tremor 0.3391299430304965 1.2860257819532055 0.1984340639805486 1.0 0.5706938493968332 182 Q99720,Q14108,O75027,O14773,O75503,Q9NR77,P11166,Q7Z406,O75787,Q14203,O95831,Q9BPX6,Q96RR1,Q9BUB7,P32929,Q6DKK2,O14936,P03886,P20700,P07602,Q15056,Q8WXW3,P00846,Q7LG56,Q96F07,Q9Y448,P41440,O75569,Q01082,O43681,Q9NQH7,P07196 32 +Aplasia hypoplasia of the thymus 0.5024695382796422 1.2848280616335352 0.1988523739854204 1.0 0.5711167996973108 16 O00192,P00813 2 +Melanocytic nevus 0.5478754064725467 1.2841760440734196 0.1990803652673864 1.0 0.5713888727138008 12 Q01082,Q15437,O75530 3 +Cherry red spot of the macula 0.5823584143922178 1.2836165946775364 0.1992761404267735 1.0 0.5713888727138008 9 P10619,P07602 2 +Resting tremor 0.4701636182440116 1.2835027956117504 0.1993159807766453 1.0 0.5713888727138008 21 P07602,O75787,Q7LG56,Q9BPX6,Q96RR1 5 +Decreased cervical spine flexion due to contractures of posterior cervical muscles 0.6587631853465443 1.2800914888974653 0.2005129616178236 1.0 0.5735147261445348 6 P50402,Q8WXH0,Q13642,P02545 4 +Abnormal dura mater morphology 0.7461538461538471 1.2797450851561674 0.2006348027763289 1.0 0.5735147261445348 3 Q9NXR1,Q8N3U4 2 +Generalized lipodystrophy 0.7240529054749062 1.278756167780457 0.2009829336126296 1.0 0.5736902288070578 4 O75844,O75431 2 +Unusual fungal infection 0.5465868527928848 1.2773317664734716 0.2014851431204682 1.0 0.5741706800548657 12 P00813,P02786,Q9Y448,P42224 4 +Hypokinesia 0.5392891512161867 1.2772275488294889 0.2015219236431 1.0 0.5741706800548657 13 Q96RR1,Q9Y3D3,P06753,O95831 4 +Orofacial dyskinesia 0.6018541184216804 1.2766834785220744 0.2017140166072746 1.0 0.5743658303762287 8 Q9BPX6 1 +Proximal amyotrophy 0.5265148181621326 1.273758319012547 0.2027490810752206 1.0 0.5766768513162985 14 P50402,Q8WXH0,P35637,P02545,Q16637,Q9H9S5,Q92734,Q13642,P07196 9 +Exercise induced muscle cramps 0.6571772680051267 1.2733385752705788 0.2028979238007635 1.0 0.5766768513162985 6 P53985 1 +Pedal edema 0.6205732639147084 1.2723878932769597 0.2032353334873433 1.0 0.5772827596061642 7 P04062,Q14108,Q96L73,Q9Y5S9 4 +Early onset of sexual maturation 0.3971280715268865 1.2714695218326717 0.2035616635341388 1.0 0.5773319748756016 45 P55011,Q15056,Q13423,Q9UIG0,P48735,P02545,Q93009,Q8N3R9,O96028,Q9UBM7,Q969N2,O14936 12 +Abnormal meningeal morphology 0.4570022275051608 1.270983051622423 0.2037346781688038 1.0 0.5773319748756016 26 Q15904,Q9UHX1,Q8TAA9,O15078,Q8N3U4,Q10713,Q9H9S5,Q9NXR1,O00192,Q9NQH7,Q14683,Q14738 12 +Amelogenesis imperfecta 0.7220969930814651 1.2709778954951785 0.2037365125344576 1.0 0.5773319748756016 4 Q6P4Q7 1 +Increased circulating antibody level 0.486435935783949 1.270941080781106 0.2037496102423039 1.0 0.5773319748756016 17 P00813,P28070,P78536 3 +Abnormal light and dark adapted electroretinogram 0.6004234081853967 1.270041535082069 0.2040698354247081 1.0 0.5775350336288786 8 P00846,P50897 2 +Abnormal full field electroretinogram 0.6004234081853967 1.270041535082069 0.2040698354247081 1.0 0.5775350336288786 8 P00846,P50897 2 +Abnormal thalamic size 0.7208024182467433 1.2658298520635778 0.2055740050013925 1.0 0.5804757616042568 4 P11166,Q9H9S5,Q9UPT5 3 +Auditory hallucinations 0.7425242910394708 1.265476879454495 0.2057004313467691 1.0 0.5804757616042568 3 Q9NWW5 1 +Depletion of mitochondrial dna in muscle tissue 0.6551238948496985 1.264594773950892 0.2060166274221422 1.0 0.5804757616042568 6 Q96RR1,Q9UBX3 2 +Morphological abnormality of the corticospinal tract 0.4711252646174536 1.264133043903618 0.2061822780655069 1.0 0.5804757616042568 18 Q13045,O00400,Q15056,P35637,P00846,Q14203,P11177,O75298,Q9UIG0 9 +Photoreceptor layer loss on macular oct 0.6643779181543483 1.263948414205618 0.2062485430322564 1.0 0.5804757616042568 2 P04439 1 +Abnormal optical coherence tomography 0.6643779181543483 1.263948414205618 0.2062485430322564 1.0 0.5804757616042568 2 P04439 1 +Abnormal heart rate variability 0.719703215168963 1.2614588996975131 0.2071435589756829 1.0 0.5812507273633145 4 Q14683,P07602,Q8N3U4 3 +Hip subluxation 0.6179866371454328 1.260814218930957 0.2073757896597823 1.0 0.5812507273633145 7 Q9UBM7,Q03252 2 +Abnormal mitochondrial shape 0.6874451727591875 1.2607912822805596 0.2073840555128847 1.0 0.5812507273633145 5 Q9GZY8 1 +Combined immunodeficiency 0.5774481775451936 1.259800288364793 0.2077414157472978 1.0 0.5814121291443836 9 P00813,Q9Y448 2 +Abnormality of the ankles 0.3903808182098388 1.2595908757919776 0.2078169887042869 1.0 0.5814121291443836 47 O00754,P07602,Q15056,Q8N0X7,Q9HD42,O75844,Q7RTS9,O75787,P02545,P06753,O75298,Q969N2 12 +Abnormal pupillary function 0.597766573828491 1.257705829959305 0.2084981630650588 1.0 0.5829506091888723 8 Q9NR77 1 +Abnormal auditory evoked potentials 0.6168879222232833 1.2558977073679105 0.2091530599050748 1.0 0.5840951138094247 7 P20700,P07196,P07602 3 +External ophthalmoplegia 0.4642573117593638 1.254834390764881 0.209538885287152 1.0 0.5844701080008377 22 P03886,O60313,Q7LG56,Q14331,Q96RR1,Q9GZY8 6 +Abnormalities of placenta or umbilical cord 0.4837923819910492 1.2544061338080723 0.2096944242137763 1.0 0.5845530829762561 17 P16278,P02545,Q01082,O60826,O75844 5 +Bone pain 0.4640527720167532 1.253448790724339 0.2100424245532612 1.0 0.5851721504190678 22 Q14108,P07602,Q9Y2U8,P51798,P48735 5 +Abnormality of pain sensation 0.4377205138857332 1.2520716623850454 0.2105437524122533 1.0 0.5862173861352553 30 P31040,Q13045,Q9NR77,O15269,Q8NCH0,O95714,O95831,P39210,P07196,P17480,Q00796 11 +Abnormality of salivation 0.3922680202689725 1.2512499774125392 0.2108432895280474 1.0 0.5866998601418182 46 Q9NR77,P55795,P55011,Q15233,Q8N0X7,Q68CQ7,P15586,O75787,Q14739,Q14203,Q03252,Q15165,Q01082 13 +Abnormal duodenum morphology 0.4964362213362943 1.248471258070309 0.2118585276619109 1.0 0.5882019774355025 16 O60566,Q8NCH0,P98175,O75419,O15287,P78536 6 +Brachydactyly 0.3628567211606821 1.246055722523311 0.2127439386897505 1.0 0.5899943839064447 82 Q13045,Q7RTS9,P02545,Q9Y366,Q9UBM7,P11166,Q9UHX1,Q8WVQ1,Q8N0X7,O95831,Q14739,Q13868,Q9Y3D3,O95155,Q9UQE7,Q9NX62,Q13555,Q15437,Q96RK4,O60826 20 +Fatigable weakness of bulbar muscles 0.4959417593232921 1.2454900836678136 0.2129516583538167 1.0 0.5899943839064447 16 Q68CQ7,P35637,Q15165,Q14203,P06753,Q92804,P43243,Q9Y5P6 8 +Diffuse white matter abnormalities 0.5472427558800232 1.2453745036648936 0.2129941208313657 1.0 0.5899943839064447 11 P16278,Q9H9S5,O14936 3 +Prematurely aged appearance 0.3965912101293682 1.2430499591638269 0.2138494241097972 1.0 0.5915227820465642 44 Q9Y487,Q03252,P02545,Q13126,O75431,O75844 6 +Skeletal muscle hypertrophy 0.3796450098541536 1.2423653266510886 0.2141018025560102 1.0 0.591868576131933 50 Q9NR77,O00754,P16278,P04066,Q15056,Q14331,Q15437,P02545,Q8NAT1,Q9H9S5,P10253 11 +Abnormal visual electrophysiology 0.3761686247506042 1.2412098524563913 0.2145282361119198 1.0 0.5923661808410894 57 P07602,O15078,P50897,P00846,O15484,O43681,O75503,Q13049,Q9GZY8 9 +Abnormal saccadic eye movements 0.4528140002448336 1.241186796924126 0.2145367510986773 1.0 0.5923661808410894 26 Q5THJ4,Q8IV08,O75306,Q10713,Q9Y4W6,O14773,P51798,P04062 8 +Progressive pes cavus 0.6821998904796833 1.2392639206510123 0.2152477754388533 1.0 0.5938635630210296 5 Q12768,O00400,O75298 3 +Capillary malformation 0.5077788574490644 1.2384886987572703 0.2155349099276999 1.0 0.5940633015622905 15 Q71SY5,Q9UQE7,Q9UHX1,Q15056 4 +Limitation of movement at ankles 0.7129267430743931 1.2345172659972612 0.2170102169348402 1.0 0.5964418602876077 4 O75844 1 +Abnormal foot bone ossification 0.7342115931464934 1.232812308809756 0.2176457979634192 1.0 0.5974010768671052 3 Q8WVQ1 1 +Malar prominence 0.6566877231529751 1.2296488107540948 0.2188286433871384 1.0 0.5999390594808451 2 Q9Y4W2 1 +Areflexia 0.3590558819104062 1.227804287883198 0.2195204456514641 1.0 0.6014808437160104 97 P51114,Q8TD16,Q71SY5,P02545,P06753,P10253,P39210,Q9NR77,O60313,Q7Z406,Q9BQT8,O75787,O95831,Q9H6K4,Q96RR1,Q13049,Q15046,O43505,Q7LG56,Q9H9S5,P41440,Q9NWS8,Q8NAT1,Q5TAQ9,P07196 25 +Recurrent gastroenteritis 0.7105459445019984 1.2250543995794063 0.2205547247208175 1.0 0.6032476785036133 4 P78536 1 +Gaze evoked nystagmus 0.5701879386838254 1.224570411146582 0.2207371219607139 1.0 0.6033914151479045 9 Q9Y4W6,P41440,Q10713 3 +Poor gross motor coordination 0.678253943749087 1.223071727662037 0.2213026059675582 1.0 0.6038870648910463 5 O75503 1 +Lymphedema 0.5293392562653604 1.2230566501206754 0.2213083003033036 1.0 0.6038870648910463 13 Q9Y2U8,P52732,Q14739,P08236,P06280,P31749 6 +Thin clavicles 0.7310879930807131 1.2205446243303917 0.2222584838497623 1.0 0.6050666628483227 3 O75844 1 +Transient ischemic attack 0.5896641728715691 1.220077844003123 0.2224353667005323 1.0 0.6050666628483227 8 O75844,P06280 2 +Ovoid vertebral bodies 0.5691953856516313 1.2197531817058032 0.2225584544211805 1.0 0.6050666628483227 9 P16278,Q96L58,P54802 3 +Chorea 0.3594322022433759 1.2187794245502006 0.2229279229089331 1.0 0.6050666628483227 93 P03886,P11166,Q99720,Q86VD7,Q96N66,P07602,P55011,Q9HD42,P00846,O75306,Q9BWD1,Q71SY5,O43681,Q9BPX6,Q9NUQ7,O14936 16 +Cachexia 0.4604901034659476 1.2186604234564868 0.2229731050637977 1.0 0.6050666628483227 21 Q99720 1 +Horizontal nystagmus 0.4550710668007554 1.217442005519224 0.2234360892137652 1.0 0.6054271175372403 24 P20700,P00846,P07602,O95831 4 +Atrioventricular canal defect 0.5682737192995593 1.2152798690801905 0.2242593671706609 1.0 0.6070003154717272 9 Q12768,Q9UHX1,Q9UBM7,O75419,O60826 5 +Nephronophthisis 0.6071376050864011 1.2122622716732778 0.2254120010753284 1.0 0.6090055633703786 7 Q15051,O15078 2 +Abnormality of malar bones 0.3660657993798324 1.211402799243028 0.2257410670832391 1.0 0.6094595527704435 65 O00754,O60566,Q8WVQ1,Q15233,Q96L58,Q9HC07,Q9Y487,Q14739,P02545,O95831,O00192,Q969N2,P11274,O75175 14 +Aplasia hypoplasia of the pubic bone 0.6425705804015915 1.211138471465575 0.2258423391157098 1.0 0.6094595527704435 6 O96028 1 +Abnormality of the spinal cord 0.3597998280099559 1.210400754017537 0.2261251527147245 1.0 0.6097452438152307 81 O75298,O00192,Q9HC21,P05067,P16278,O00400,Q9UHX1,Q96L58,Q10713,Q96RR1,Q5H8A4,P20700,O00754,Q15056,O15078,Q9Y2U8,Q7LG56,P34059,Q9H9S5,O15287,O96028,P31749,P07196,Q9UIG0 24 +Preaxial hand polydactyly 0.5269751718374956 1.2101779151315024 0.2262106305869287 1.0 0.6097452438152307 13 O96028,Q9UHX1 2 +Basal ganglia cysts 0.6062394158420104 1.2082426170796454 0.2269539535400111 1.0 0.6112668780167301 7 P00846 1 +Hyperlordosis 0.3744534403431837 1.205906454503642 0.2278535616374726 1.0 0.612303141781975 54 P16278,P04066,Q8WVQ1,Q15056,Q7RTS9,Q8TD16,Q14331,P02545,P06753,Q9Y448,Q9H9S5,Q96HY6,P11274 13 +Abnormal placenta morphology 0.5662797109835273 1.205601645649193 0.2279711243726958 1.0 0.612303141781975 9 P16278,P02545,O75844,Q01082 4 +Retinal detachment 0.458530040457587 1.2055105099367251 0.2280062831979392 1.0 0.612303141781975 21 Q13045,Q8NCH0,P31749,O43505,P52732,Q14331,Q8NAT1,Q9H9S5,O15484,P04439,P35222 11 +Cellulitis 0.6738544210426334 1.205022428077642 0.228194643787813 1.0 0.612303141781975 5 P02545 1 +Opisthotonus 0.4532508148474492 1.204823781524717 0.2282713372091596 1.0 0.612303141781975 24 Q99720,P07602 2 +Aplasia hypoplasia of the breasts 0.565935572372152 1.2039312887779496 0.2286161371700865 1.0 0.6126754264298686 9 P02545,Q9Y619,O75419 3 +Noncompaction cardiomyopathy 0.7263665926106198 1.2020101612159002 0.2293595912471175 1.0 0.6136062294331349 3 Q15233 1 +Protuberant abdomen 0.6400358711065857 1.2003468559643096 0.2300046592943243 1.0 0.6149688507244196 6 Q7RTS9 1 +Ankle clonus 0.5251098396328104 1.2000147852294474 0.2301335983235992 1.0 0.6149688507244196 13 Q969N2,O75787,O75298,P07602 4 +Abnormal heart valve morphology 0.3586372839374303 1.1977244742628743 0.2310242981085142 1.0 0.6169637999892427 87 P02545,P06753,O00192,P06280,P16278,Q9UHX1,Q8NCH0,Q96L58,Q6ZXV5,Q9BUB7,Q6PGP7,Q5H8A4,O95155,Q15056,Q15233,P08236,O75431,P51798,O15287,O96028,Q9UQE7,Q01082,O60826,O75844,Q9UIG0 25 +Abnormal circulating protein concentration 0.328545544368668 1.1974128432438684 0.2311456801767315 1.0 0.6169637999892427 170 Q86VD7,Q9HC07,O43772,P14174,P02545,P06753,P10253,P39210,Q9Y6N5,P49748,Q9Y487,Q7Z406,P53985,O95831,Q6ZXV5,Q9BPX6,Q96RR1,Q13049,Q15056,P23786,O43505,Q7LG56,O43707,Q9H9S5,P09493,Q8N1F7,P41440,Q9NWH9,Q14331,Q8NAT1,P15291,Q8NFF5,P07196 33 +Slow decrease in visual acuity 0.5313936653291864 1.1965601018717755 0.2314780594333736 1.0 0.6172350768283031 12 P03886,P00846,O75306,P35222,O95140,P31749 6 +Dyschromatopsia 0.6033518453613411 1.195320505897883 0.2319618310107163 1.0 0.6180771953594029 7 Q9Y4W6,O60313,Q9H6K4 3 +Quadriceps muscle weakness 0.6030755040424663 1.194083918652277 0.2324451431178771 1.0 0.6186069162450758 7 Q96RR1,Q13049 2 +Abnormality of vitamin b12 metabolism 0.5239675025260245 1.1937903383480757 0.2325599919690439 1.0 0.6186069162450758 13 P41440,Q9NUN5 2 +Abnormal hand bone ossification 0.6381710461151424 1.1924082345918037 0.2331012130272665 1.0 0.6192404973876068 6 Q96L58,Q8WVQ1 2 +Abnormality of skin physiology 0.3539311860171851 1.192373194937267 0.2331149458837629 1.0 0.6192404973876068 103 P22830,Q8NCH0,O00192,P49748,P28070,P02786,Q9NZ08,P16615,P52732,P14174,Q92542,Q9Y448,P00813,Q9UBM7,Q9NUN5,P78536 16 +Abnormality of skeletal muscle fiber size 0.4532826871799338 1.1919996565653364 0.2332613799325722 1.0 0.6192404973876068 23 Q7Z406,O95831,P02545,Q9BPX6,Q96RR1,Q13049 6 +Pain 0.3372945749237435 1.1918215977571258 0.2333312052777489 1.0 0.6192404973876068 192 Q14108,P14174,P02545,O00192,P06280,Q9NR77,Q70HW3,P49748,P28070,Q14203,Q14739,P42892,Q96RR1,Q969N2,Q13049,P50336,O14936,P20700,P07602,Q15056,P23786,P00846,Q7LG56,Q03252,O43707,Q9H9S5,P51798,Q8N1F7,P48735,Q68CQ7,Q13423,O75569,Q9NZ08,Q9NWH9,Q15165,Q01082,Q96HY6,Q9NUQ7,O75844,Q14566 40 +Abnormal aldolase level 0.701055564179791 1.1873532308710513 0.2350883196048001 1.0 0.6196854893908355 4 Q9H9S5,O43505 2 +Polyphagia 0.601458627972735 1.1868489141042258 0.2352872209103704 1.0 0.6196854893908355 7 O95714,O95155,Q4J6C6 3 +Immunodeficiency 0.3588171185756991 1.1861339415210586 0.2355694084541182 1.0 0.6196854893908355 69 Q13432,O00754,O60566,P02786,Q15437,P14174,Q03252,Q9Y448,P11274,O00192,Q6PGP7,P00813,O96028 13 +Abnormal morphology of the abdominal musculature 0.5621591366402215 1.1856014230497842 0.2357797400171168 1.0 0.6196854893908355 9 Q96JJ3,Q8NCH0 2 +Abnormality of the vasculature of the eye 0.3575271300548888 1.18553207469494 0.2358071406692445 1.0 0.6196854893908355 79 P03886,P16278,Q15555,P04066,P07602,Q15056,P28070,P02786,P00846,Q9NZ08,O75306,Q14331,Q14739,O15484,O00192,P10619,P06280 17 +Abnormal circulating aspartate family amino acid concentration 0.5621245528289909 1.185433564291947 0.2358460675894189 1.0 0.6196854893908355 9 Q9NVS9,P55263,P16930,Q6PGP7,Q99707 5 +Atrophy degeneration affecting the brainstem 0.5292132951846692 1.184961771412429 0.2360325621307895 1.0 0.6196854893908355 12 P20700,Q13813,Q96RR1 3 +Dysgraphia 0.4856913836651066 1.1836505996736246 0.2365514016268259 1.0 0.6202176344107607 16 P05067,Q15056,Q9UIG0 3 +Cavernous hemangioma 0.6685912206551765 1.1834378854135108 0.23663565005601 1.0 0.6202176344107607 5 Q15437 1 +Expressive language delay 0.5615055625390897 1.1824291998646137 0.2370354427335654 1.0 0.620716765650886 9 P31040,Q9UHX1,Q96L73 3 +Small placenta 0.7212522886013566 1.181946807182263 0.2372268077891055 1.0 0.620716765650886 3 O75844 1 +Short umbilical cord 0.7212522886013566 1.181946807182263 0.2372268077891055 1.0 0.620716765650886 3 O75844 1 +Sclerocornea 0.5100577315290443 1.1811644790285651 0.2375373892046846 1.0 0.6211796553934549 14 O75569,Q9UBM7,O96028,O15078 4 +Dilatation of the ventricular cavity 0.7206043956043965 1.1794062576116269 0.2382364445669305 1.0 0.6223073400239044 3 P27635,Q9NXR1 2 +Aplasia cutis congenita of scalp 0.5995687009188675 1.1783928099913497 0.2386400427921839 1.0 0.6230113926153252 7 O96028 1 +Neuronal loss in central nervous system 0.5277865199329507 1.1773717967620192 0.2390471416619453 1.0 0.6237237884913306 12 P04062,P07602,O15118 3 +Small earlobe 0.5803835247004941 1.1769762074330576 0.2392050028293328 1.0 0.6237854366711054 8 P98175,P10586 2 +Ankyloglossia 0.5802619211905529 1.1764115281883043 0.2394304672315081 1.0 0.6240232087632185 8 P02545,O75844,P11274 3 +Delayed social development 0.7191519142345665 1.1737117098151524 0.2405105183374334 1.0 0.6261357863944276 3 Q9Y3C6 1 +Heterotaxy 0.6332503928958336 1.171465844344638 0.241411579143129 1.0 0.6274090080420016 6 O96028 1 +Atlantoaxial abnormality 0.6329652831321396 1.170252674456364 0.2418993008268239 1.0 0.6274090080420016 6 Q96L58,Q7RTS9 2 +Acanthosis nigricans 0.5327461784837522 1.1700438559781785 0.2419833204613495 1.0 0.6274090080420016 11 P02545,P28070,O75431 3 +Supernumerary tooth 0.5976722581082247 1.1699084986085626 0.2420377934513817 1.0 0.6274090080420016 7 Q9UHX1 1 +Abnormality of primary teeth 0.5077121733148131 1.1679586867548613 0.2428234297767375 1.0 0.627935714063717 14 P02545,O75844,P51798 3 +Reduced visual acuity 0.3249311097125438 1.166817510994484 0.2432840737991213 1.0 0.6283292909345531 136 Q71SY5,P16278,A2RRP1,O60313,O43395,Q9UHX1,O43676,Q10713,O75251,Q8NHS3,Q9NXR1,Q9H6K4,Q9H061,P03886,P07602,O15078,P50897,P00846,O43505,P52732,Q9Y4W6,P30533,Q9H9S5,O15484,P51798,Q96CU9,O43172,P31749,Q15051,Q15555,Q8WWY3,Q9NZ08,O75306,Q86YV9,O43681,O75380,P49770 37 +Cystic renal dysplasia 0.7172118876824676 1.1661079399129732 0.2435708068615611 1.0 0.6283292909345531 3 P23786 1 +Aortic regurgitation 0.4385367533914878 1.165239380730365 0.2439221090694929 1.0 0.6283292909345531 27 O00754,O60566,Q9UHX1,Q9NZ08,P02545,Q01082,Q6ZXV5,O75844,P11274 9 +Myoclonus 0.3480838412662847 1.16415180047321 0.2443624993414359 1.0 0.6287666303652563 110 Q05639,Q01105,Q14108,P27544,O96008,Q96N67,O14773,O75503,P05067,Q5THJ4,P11166,Q9UBX3,Q96RR1,Q13813,P00403,P03886,O14936,P07602,P50897,P00846,Q03252,Q9Y4W6,Q9Y4G8,Q96F07,Q96CU9,P31749,Q9NWS8,Q9NWW5,P23378 29 +Aplasia hypoplasia of the lungs 0.405147895195311 1.1634691202131189 0.2446392198133389 1.0 0.6291303013129972 35 P98175,Q96L58,O75419,P02545,Q14739,P25705,O96028,Q9UBM7,O75844 9 +Arthralgia 0.4002557247764073 1.1628429363065385 0.24489323315415 1.0 0.6294352071168888 38 Q15056,P28070,Q9NZ08,P14174,P02545,Q03252,Q96HY6,Q9NUQ7,Q969N2,P06280 10 +Abnormality of the upper arm 0.4505545230133695 1.161926349714183 0.2452653828475248 1.0 0.6300432471489487 22 P02545,Q7RTS9 2 +Blindness 0.3545759046152201 1.1590488062252478 0.2464362914521978 1.0 0.6324316666031939 93 P03886,P16278,P07602,O15078,P50897,O43676,P00846,Q9NZ08,O43505,P52732,O75251,Q9H9S5,Q8NHS3,O15484,O75380,Q96CU9 16 +Abnormal retinal vascular morphology 0.3686338251191887 1.1576595671626824 0.2470029902281112 1.0 0.6334117683907595 56 P16278,P03886,O43395,Q15555,P07602,Q15056,Q8WWY3,P00846,O75306,Q14331,O15484,P04439,O00192,Q8WYQ5,P10619,O43172,P35222,Q9UIG0 18 +Sepsis 0.4498826797311482 1.1573683129508134 0.2471219143732401 1.0 0.6334117683907595 22 P42892 1 +Impairment of activities of daily living 0.3665871382904114 1.1569565116830365 0.2472901283934936 1.0 0.6334935097268825 59 P20700,P11166,Q99720,P07602,O75298,O43681,P11274,P07196 8 +Diastasis recti 0.693047540533086 1.155574426628964 0.2478552733753118 1.0 0.6342419908453053 4 Q96JJ3,Q15910,Q8NCH0 3 +Fasciculations 0.402578110139879 1.1545283790350245 0.2482836106608199 1.0 0.634290235701391 36 Q5THJ4,P07602,P51114,P35637,Q8TD16,Q9BQT8,Q14203,O95831,Q9NQT5,Q92734,P07196,P06280,Q9NWS8 13 +Telangiectasia of the skin 0.4493193177374217 1.1535461739670458 0.2486862767905326 1.0 0.6349698506843986 22 P02545,Q96JJ3,Q8IZA0,P06280 4 +Cutaneous finger syndactyly 0.7126373626373635 1.1481893800588858 0.2508903924343948 1.0 0.6391927925672328 3 Q9Y619,Q9Y2U8 2 +Steppage gait 0.449920443001172 1.147723072155302 0.2510829033881907 1.0 0.6393327408465327 21 Q9NR77,O15269,Q15046,P02545,Q5TAQ9,P07196 6 +Hypoplastic labia minora 0.6270887135768025 1.145255299354231 0.2521034170030178 1.0 0.640877778344105 6 O95714,Q9Y619,O75419 3 +Clitoral hypoplasia 0.6270887135768025 1.145255299354231 0.2521034170030178 1.0 0.640877778344105 6 O95714,Q9Y619,O75419 3 +Impaired distal tactile sensation 0.659048168803341 1.1443334198148294 0.2524853885643638 1.0 0.641465934793311 5 P39210,Q5TAQ9 2 +Abnormal corneal epithelium morphology 0.4514447308986493 1.1420073635186172 0.2534509589308964 1.0 0.6426236470212588 19 Q9NZ08,P02545,P39210,O75844,Q96EK5 5 +Abnormality of the tongue 0.3498803854800251 1.1404560554794885 0.2540963506962408 1.0 0.6438308297085229 103 P98175,P51114,Q71SY5,P02545,P10253,Q9UBM7,P16278,Q9BQT8,O95831,P20700,O00754,Q15056,O15078,Q03252,Q9H9S5,O75431,P11274,P31749,Q9NWS8,P04066,Q9NQT5,Q15437,Q14331,Q01082,O60826,O75844,Q9NUN5,P07196,Q9UIG0 29 +Paroxysmal involuntary eye movements 0.4437087932448115 1.1386488299242223 0.2548496532229509 1.0 0.6450361320953447 24 P03886,P11166,O43676,O75380,Q96CU9 5 +Abnormal cellular phenotype 0.3399737110535252 1.1377970427194457 0.2552052401236877 1.0 0.6452332703236001 208 Q14108,P26038,Q4J6C6,O43772,P14174,P02545,O14773,O75503,O00192,Q7KZN9,P11166,O60566,Q70HW3,Q9UBX3,P49748,P28070,O43676,Q7Z406,P02786,O75787,P15586,O75251,Q14739,P00813,Q6PGP7,Q96RR1,Q969N2,Q9BUB7,P00403,P03886,P20674,O00754,P07602,Q15046,P23786,P00846,Q7LG56,Q9Y4W6,Q9Y448,P11177,P51798,O15287,P78536,Q9Y2R0,Q96CU9,O75306,Q15437,Q9NWW5,O75380,O75844,Q9GZY8 51 +Polyarticular arthropathy 0.6358143367206756 1.136788127758622 0.255626867607214 1.0 0.6459478269552601 2 Q9UBC1 1 +Abnormality of humoral immunity 0.3612159249629715 1.136353173108415 0.2558087852370292 1.0 0.6460562092372146 63 Q14108,P02786,P28070,O75787,P14174,P02545,Q03252,Q9Y448,P00813,Q969N2,P78536 11 +Coxa valga 0.4411450991100117 1.1344787570231512 0.2565937795330457 1.0 0.6473351213301105 25 P16278,O00754,P04066,Q8WVQ1,Q96L58,P02545,O75530,O75844,P11274 9 +Abnormal urine carbohydrate level 0.5257699045620334 1.1337877081914929 0.2568836082298495 1.0 0.6475551533878912 11 P16278,O00754,P04066,P10253 4 +Gynecomastia 0.447817717885444 1.1336063814212536 0.2569596950392234 1.0 0.6475551533878912 21 P51809,Q15437,Q01082,P31751,P31749 5 +Abnormality of thalamus morphology 0.4445575102928485 1.1321599020163855 0.2575672146477337 1.0 0.648445943080692 23 P11166,Q9UPT5,P31749,O75306,Q9H9S5,Q9NXR1,Q96RR1,O00443,Q9GZY8,Q96KP1,P49792 11 +Limited elbow extension 0.519110690000734 1.1312204955266538 0.2579622975360114 1.0 0.6490258779912533 12 Q96L58,Q7RTS9,Q8WVM7 3 +Insulin resistance 0.4496210586475144 1.130008617940935 0.2584725931464358 1.0 0.6499578681555666 19 Q03252,P02545,Q9Y6M1,O75431,O75844 5 +Ureteral duplication 0.5304697552037484 1.128622896785318 0.2590569475198316 1.0 0.6510749784341037 10 P23786,O75844,O15078 3 +Increased circulating androgen concentration 0.6336171381488547 1.12704114526228 0.2597250851682369 1.0 0.6524013355550253 2 O14802 1 +Talipes valgus 0.6226889986886284 1.1265520373093167 0.2599319274540932 1.0 0.6525681614690282 6 Q9HD42,O00754 2 +Decreased circulating total igm 0.5298794717004338 1.1256241111790026 0.2603246579478724 1.0 0.6532012340625071 10 P00813,Q969N2 2 +Upper limb muscle weakness 0.4292430141651943 1.1251502428914826 0.2605253737342665 1.0 0.6533286005854732 28 Q12824,Q8N0X7,P50402,Q8WXH0,P31749,P00846,O95140,P02545,Q92734,P55265,Q13642,P07196,P50336 13 +Limb joint contracture 0.3438941055893179 1.1248405657110565 0.2606566011373934 1.0 0.6533286005854732 112 Q99720,Q86XL3,Q8IZA0,Q8TD16,O75419,Q71SY5,P02545,P06753,Q9HC21,Q9NR77,Q8WVQ1,Q96L58,Q15392,P42892,Q9BUB7,O95155,P23786,Q9H9S5,O75530,P11274,O75844,P07196 22 +Eruption failure 0.5875173432079602 1.1245013048009371 0.2608004172877245 1.0 0.6533366787795449 7 O75844 1 +Impaired vibration sensation in the lower limbs 0.449089435703526 1.1206319189684455 0.2624445725031024 1.0 0.6562371435840515 18 Q9NR77 1 +Adrenocorticotropic hormone deficiency 0.6319692392199888 1.1197352035346704 0.2628266187322525 1.0 0.6562371435840515 2 P04637 1 +Sudden loss of visual acuity 0.6319692392199887 1.1197352035346693 0.262826618732253 1.0 0.6562371435840515 2 P35222 1 +Abnormally large globe 0.5485027702319542 1.1193385125585835 0.2629957516397203 1.0 0.6562371435840515 9 P30533,Q9H9S5,O75431,O14936 4 +2 3 toe cutaneous syndactyly 0.6308706399340782 1.1148667033004371 0.2649075470732489 1.0 0.6583023375665176 2 P27635 1 +Tongue thrusting 0.6308706399340782 1.1148667033004371 0.2649075470732489 1.0 0.6583023375665176 2 Q14683 1 +Hand apraxia 0.6308706399340782 1.1148667033004371 0.2649075470732489 1.0 0.6583023375665176 2 Q14683 1 +Submucous cleft of soft and hard palate 0.4381275369821064 1.1133061935054744 0.2655769473505778 1.0 0.6584366620511509 25 P62266,O75844,Q15392,Q8N3U4,O75419,P02545,O43505,Q8NAT1,Q9H9S5,Q9Y619,Q8WYQ5 11 +Limb tremor 0.6514488151468205 1.1132338805702249 0.2656079951080816 1.0 0.6584366620511509 5 Q9NR77 1 +Increased intracranial pressure 0.4433563487998747 1.113089357237648 0.2656700540877788 1.0 0.6584366620511509 22 Q9NZ08,P07602,Q15437 3 +Cirrhosis 0.3885795355272198 1.110726530497045 0.266686078867389 1.0 0.6598989395616384 41 P22830,P11717,Q14108,Q9NWH9,O75787,Q14739,P39210 7 +Cataplexy 0.68132268121825 1.1091243717564392 0.2673765323689721 1.0 0.6607609622295939 4 O15118 1 +Aortic valve stenosis 0.5463559312837287 1.108928513380166 0.2674610221549098 1.0 0.6607609622295939 9 P16278,O60826,O75844 3 +Focal t2 hyperintense brainstem lesion 0.442579091897495 1.107816287298007 0.2679411645592713 1.0 0.6610857392036705 22 P03886,O43676,Q96CU9,O75380 4 +Flat forehead 0.6182162012584327 1.107551102122358 0.2680557310571883 1.0 0.6610857392036705 6 Q13555,Q9Y448 2 +Narrow nasal bridge 0.7021326507198309 1.107109523917183 0.2682465783468428 1.0 0.6610857392036705 3 Q15233 1 +Aplasia hypoplasia of the phalanges of the hand 0.3631032958423574 1.1070170559097905 0.2682865542480273 1.0 0.6610857392036705 57 Q9UHX1,Q8WVQ1,Q7RTS9,Q14739,P02545,Q9Y448,P51798,Q9Y366,O60826,O75844,P11274 11 +Abnormal oral mucosa morphology 0.3574621669971711 1.106518018745686 0.2685023693494122 1.0 0.6610857392036705 64 P16278,P20700,O00754,Q14108,Q15056,Q96JJ3,Q9NZ08,Q15392,Q14739,P08236,O75431,Q9UBM7,Q9NUN5 13 +Dysplasia of the femoral head 0.70027024186324 1.0998375937866078 0.2714028893077556 1.0 0.6634451481394741 3 O75431 1 +Thick hair 0.6152651078484723 1.0950228632491306 0.273506620175346 1.0 0.6642712374207219 6 Q9Y487 1 +Abnormality of hepatobiliary system physiology 0.3499363885768768 1.0937751518273282 0.2740536046153692 1.0 0.6650272066045017 88 P22830,P03886,P55263,O15118,P23786,P00846,O43772,O75787,P39210 9 +Abnormality of the pubic hair 0.6144319629928932 1.0914872420928046 0.2750585426116787 1.0 0.6664218183089005 6 P57740,P51809 2 +Adenomatous colonic polyposis 0.6767369420957005 1.0909892082367934 0.275277631225209 1.0 0.6665902081730436 4 P20585 1 +Bradykinesia 0.4347376895758631 1.0895252530358197 0.275922324940081 1.0 0.6674706111382388 25 O75569,O75787,Q14203,P06753,Q96RR1,Q6DKK2 6 +Ventricular tachycardia 0.4934896601433018 1.0878947038183402 0.2766415944587579 1.0 0.6685145550961249 14 P23786,O43772 2 +Abnormality of the nasal tip 0.3442775738163643 1.085852504614958 0.2775442527891263 1.0 0.6690393636248837 106 Q96N67,Q71SY5,P02545,O00192,Q96EK5,P16278,Q9UHX1,Q9Y487,O95831,Q13868,P42892,O14936,P23786,P52732,Q9Y448,O75431,Q9UQE7,Q01082,Q9BSJ2,P10586,O75844 21 +Headache 0.3485779729775077 1.0842914303685578 0.2782356037244922 1.0 0.6693564976372982 77 P31040,Q02241,P06753,P05067,P11166,O60313,Q9Y6N5,P57740,P55265,Q96RR1,Q969N2,P00403,P03886,P23786,P00846,Q7LG56,O43707,Q8N1F7,P04062,P35222,P31749,P54277,Q9NZ08 23 +Abnormal placental size 0.675013796754892 1.0841801186169746 0.2782849449464846 1.0 0.6693564976372982 4 P02545,O75844 2 +Fatigable weakness of swallowing muscles 0.5038497381083644 1.084176907816408 0.2782863682881988 1.0 0.6693564976372982 13 Q68CQ7,P35637,Q15165,Q14203,Q92804 5 +Abnormality of endocrine pancreas physiology 0.6125801177168286 1.0836307664258065 0.2785285438160247 1.0 0.6694247738928983 6 P53985 1 +Streak ovary 0.5783107941037817 1.083387752198716 0.2786363497259039 1.0 0.6694247738928983 7 P57740,P51809 2 +Slender long bone 0.5036200945137798 1.0829264825648282 0.2788410561222443 1.0 0.6694247738928983 13 Q96L58,Q9Y487,Q969N2,O75419 4 +Abnormal circulating proteinogenic amino acid derivative concentration 0.4233848498046081 1.082061820099148 0.2792250593954657 1.0 0.6694247738928983 28 P03886,P20674,P22695,P00846,Q9NUN5,Q7LG56,P25705,Q9BUB7,P32929 9 +Respiratory tract infection 0.3234462276111945 1.080541158994804 0.2799012687095681 1.0 0.6694247738928983 175 P26038,Q7RTS9,P14174,Q71SY5,P06753,P10253,P54802,Q13432,P16278,P49748,Q9Y487,P02786,P15586,Q9NXR1,P00813,P20700,O00754,P07602,Q15056,O43707,Q9Y448,P08236,P51798,Q8N1F7,O96028,P11274,P04066,Q86YV9,O60826,Q9UIG0 30 +Premature skin wrinkling 0.4397653398929946 1.0795537712361143 0.2803409368512517 1.0 0.6694247738928983 21 P02545,Q9Y487,O75844 3 +Retinal arteriolar tortuosity 0.5028152800760007 1.0785444963017257 0.280790835621779 1.0 0.6694247738928983 13 O00192,P00846,Q15056 3 +Abnormal larynx morphology 0.4103972977603699 1.0771235504391936 0.2814250731910688 1.0 0.6694247738928983 31 Q9UHX1,P07602,P02545,Q01082,Q96HY6,O00192 6 +Tics 0.5588410791789123 1.0770440387156834 0.281460591857507 1.0 0.6694247738928983 8 P11274,Q9UHX1 2 +Calcinosis 0.6425780979368023 1.0769917085547929 0.2814839699132179 1.0 0.6694247738928983 5 P02545,O75844 2 +Abnormality of the metacarpal bones 0.3759446035259222 1.076145441992828 0.2818622152781103 1.0 0.6699814395894519 45 P16278,Q8WVQ1,Q9NX62,Q96L58,Q7RTS9,Q14739,Q9Y448,P08236,P51798,Q9Y366,Q9UBM7,O96028 12 +Lower limb pain 0.6102862074628165 1.073903276997301 0.2828660344608353 1.0 0.6713373146779887 6 P00846 1 +J shaped sella turcica 0.640728522501317 1.0694448066399709 0.2848692865055606 1.0 0.6750574066248548 5 O75431 1 +Emphysema 0.5187152349683007 1.0689429657126237 0.2850953699280949 1.0 0.6751500279367734 10 P06280 1 +Pes cavus 0.3389615100861148 1.067242986839067 0.2858621258021743 1.0 0.676031195217661 113 Q99720,O75175,Q9HD42,Q71SY5,P02545,P06753,O75298,Q8N3R9,P39210,Q00796,Q9NR77,Q5THJ4,O60313,O00400,Q8N0X7,O95831,Q10713,Q14739,Q9H6K4,Q96RR1,P55011,Q15046,Q9Y448,O75530,Q5TAQ9,O00764,P07196 27 +Neoplasm of the ear 0.6698675456906205 1.0638636965846906 0.2873904509379446 1.0 0.6789544613668675 4 Q15046 1 +Posteriorly rotated ears 0.3303349484502545 1.0631698671864485 0.2877049247435745 1.0 0.6793520250423735 124 P98175,Q4J6C6,Q9HC07,O75419,Q9UBM7,O60566,Q9UHX1,Q8WVQ1,Q8NCH0,Q96L58,Q15392,Q13868,P42892,Q13049,O95155,Q15056,O15078,P23786,O43505,Q9H9S5,O75530,O96028,Q9UQE7,Q15555,Q8NAT1,Q96RK4,Q9UIG0 27 +Global brain atrophy 0.4368590685594005 1.0600534335446237 0.2891202909987309 1.0 0.6820010113051282 21 Q9NVS9,Q9UHX1,P07602,P35637,O75306,Q969N2 6 +Emg myopathic abnormalities 0.3987178627500437 1.0584210048059477 0.2898635474385167 1.0 0.6834073591815257 33 Q7Z406,Q7LG56,P02545,P06753,Q9H9S5,Q96RR1,Q13049,P07196 8 +Extramedullary hematopoiesis 0.6682182377405013 1.0573590342931505 0.2903477602203099 1.0 0.6840414878466077 4 P98175 1 +Abnormal cardiac ventricular function 0.4319104090246898 1.0568360556471312 0.2905864158594113 1.0 0.6840414878466077 24 P03886,P49748,Q7LG56,P02545,Q9H9S5,P10253,Q96RR1,O75844,P00403 9 +Chronic pulmonary obstruction 0.5544141255903469 1.0565498880055155 0.2907170612130605 1.0 0.6840414878466077 8 O00192,P06280 2 +Sensory neuropathy 0.3861125087110932 1.0565405776985382 0.2907213123514203 1.0 0.6840414878466077 39 P03886,Q8IV08,O95831 3 +Anotia 0.6663747633935108 1.050092569211338 0.2936755548032252 1.0 0.688828849852471 4 Q9Y619,O75419 2 +Meningocele 0.4975402005145115 1.0498358641745864 0.2937935830444582 1.0 0.688828849852471 13 Q8TAA9,O15078,Q10713,Q9H9S5,O00192 5 +Limb pain 0.5092055415455292 1.0477882020826077 0.2947361993405648 1.0 0.6892410909229162 11 O75569,P00846,O15269 3 +Ileus 0.6655917526128858 1.0470074619553054 0.2950961366556401 1.0 0.6892410909229162 4 P50336,Q01844 2 +Verrucae 0.6857142857142868 1.0431441344503676 0.2968815426777387 1.0 0.6892410909229162 3 Q13043,P16615 2 +Hypermetric saccades 0.6638568523867613 1.040174709294698 0.2982587391443099 1.0 0.6919662310552211 4 O14773 1 +Chorioretinal coloboma 0.5075936254239632 1.0394313415987888 0.2986041740729397 1.0 0.6924219545493767 11 O15078,Q10713,Q01082,O60826,P31749,O14936 6 +Meningitis 0.5313156643452426 1.0360994402668398 0.3001557533354262 1.0 0.6946270363403121 9 P02786,Q9NZ08 2 +Abnormal thyroid stimulating hormone level 0.6127437517165553 1.0348243790193694 0.3007509354673354 1.0 0.6946270363403121 2 O14654 1 +Elevated circulating growth hormone concentration 0.6127437517165553 1.0348243790193694 0.3007509354673354 1.0 0.6946270363403121 2 O00170 1 +Abnormal urine hormone level 0.6127437517165553 1.0348243790193694 0.3007509354673354 1.0 0.6946270363403121 2 P04637 1 +Increased urinary cortisol level 0.6127437517165553 1.0348243790193694 0.3007509354673354 1.0 0.6946270363403121 2 P04637 1 +Dilated fourth ventricle 0.3580362799123623 1.0317939361191055 0.3021686605695168 1.0 0.697208423866209 51 O60826,O15078,P23786,Q9Y487,O43505,Q8NAT1,P15291,Q9H9S5,Q9UBM7,O14936 10 +Progressive leukoencephalopathy 0.6826923076923088 1.0314096359052216 0.3023487640503868 1.0 0.697277769996103 3 P31040,Q5JTZ9 2 +Fatigable weakness of respiratory muscles 0.4716137623641604 1.0279211733317517 0.3039869088322584 1.0 0.7002586748787564 15 Q68CQ7,P35637,Q7LG56,Q14203,Q15165,Q92804 6 +Hypergonadotropic hypogonadism 0.4826781380199759 1.0271075299114658 0.304369833388586 1.0 0.700548100919643 14 P02545,Q96RR1,Q16740,Q7LG56 4 +Infantile axial hypotonia 0.5038156494052397 1.0198565900548706 0.3077964798804267 1.0 0.7063359219774532 11 O00754,P07602,Q8N3U4,Q15043,Q14683,Q9GZY8 6 +Hypopigmentation of the skin 0.3562558255156041 1.01922601762802 0.3080956775429908 1.0 0.7066735506131681 53 P07602,O95714,P31749,Q8IZA0,O15287,Q9Y2U8,Q15437,Q86YV9,P02545,Q01082,P51798,O00192,Q6PGP7,P50336,Q96L73 15 +Osteolysis involving bones of the feet 0.627861400537609 1.0170555052534886 0.3091270254625562 1.0 0.7066982885282916 5 O75844,O75431 2 +Foot acroosteolysis 0.627861400537609 1.0170555052534886 0.3091270254625562 1.0 0.7066982885282916 5 O75844,O75431 2 +Laryngomalacia 0.4579973388189168 1.016564233175935 0.3093607762639039 1.0 0.7066982885282916 16 P02545,P07602 2 +Corneal ulceration 0.6276334343462924 1.0161293190261804 0.3095678089982487 1.0 0.7066982885282916 5 P02545,O75844 2 +Generalized clonic seizure 0.5965608287188796 1.0158222996643456 0.3097140149181592 1.0 0.7066982885282916 6 P07602 1 +Cerebellar atrophy 0.3078247312876038 1.0154080153485894 0.3099113738509247 1.0 0.7066982885282916 142 Q14108,O14773,O75503,O60313,O00400,Q8N0X7,O75787,Q10713,Q13868,Q8NHS3,Q9NXR1,Q9H6K4,Q96RR1,Q969N2,Q5H8A4,Q13813,Q6DKK2,O14936,O00754,Q8IV08,Q7LG56,Q9Y4W6,Q96F07,Q9H9S5,P51798,P41440,Q96CU9,P17480,Q9NQT5,Q9GZY8 30 +Delayed ability to walk 0.3416735089609325 1.0151197552908626 0.3100487456785927 1.0 0.7066982885282916 73 Q99720,Q01105,Q86VD7,Q8N3U4,O95714,Q10713,Q6ZXV5,Q5H8A4,O14936,P20700,P55011,Q15046,Q15233,Q03252,Q9UBB6,Q96N66,O75175,Q15042,Q14738 19 +Papillary renal cell carcinoma 0.6272696424335916 1.014651454842694 0.3102720023997216 1.0 0.7066982885282916 5 P02545 1 +Megaloblastic anemia 0.5268308581462879 1.0144298326047834 0.3103776951803492 1.0 0.7066982885282916 9 P41440 1 +Abnormal renal tubule morphology 0.4141753838739425 1.0143894808431162 0.3103969416995751 1.0 0.7066982885282916 28 P03886,Q15056,P23786,P00846,O75306,Q9NQH7,P06280 7 +Tonic seizure 0.4208965993109506 1.013911269418931 0.310625093477618 1.0 0.7066982885282916 26 Q05639,Q01105,Q96JM3,Q9Y6N5,P07602,Q15046,Q00610,P27635,Q96N67,Q96T60,Q969N2,Q9NZJ7,O14936 13 +Large earlobe 0.5264430717924989 1.0125574177327454 0.3112716079875817 1.0 0.7069790627166628 9 Q15392,Q96N67 2 +Profound sensorineural hearing impairment 0.6263881591721554 1.0110713402795042 0.3119822862595498 1.0 0.7075775187228335 5 Q9NR77,P55011 2 +Coarse facial features 0.3413081535252378 1.010918377126643 0.3120554976053795 1.0 0.7075775187228335 73 P16278,O00754,P04066,Q15056,Q7RTS9,P15586,O95831,Q01082,P08236,P54802,P10619,P06280 12 +Abnormal conus terminalis morphology 0.5260652164096892 1.010733162355325 0.3121441604006474 1.0 0.7075775187228335 9 O96028,Q5H8A4 2 +Aplasia hypoplasia of the earlobes 0.5017477227063124 1.0091499119313043 0.3129027439461675 1.0 0.7083906454002378 11 P98175,P10586 2 +Proptosis 0.3523825403280448 1.0090301220383768 0.3129601882949619 1.0 0.7083906454002378 59 O75419,P02545,Q5KU26,Q9UBM7,A2RRP1,Q8WVQ1,Q96L58,Q96JJ3,O75718,Q9NXR1,Q6PGP7,Q5H8A4,O00754,O75431,O15287,O96028,P31749,Q9NX62,Q01082,O75844 20 +Delayed epiphyseal ossification 0.6552772865405241 1.0064470360802935 0.314200577148181 1.0 0.7094703994206013 4 Q96L58 1 +T lymphocytopenia 0.5008648470863326 1.004580669495642 0.3150988091706077 1.0 0.7108078476775797 11 P00813,Q9Y448 2 +Subcortical heterotopia 0.5931602558965053 1.0014706016395851 0.3165993460769356 1.0 0.7132254739218148 6 P07942,Q9BSJ2 2 +Abnormal upper limb bone morphology 0.3352334483260165 1.0014051453199924 0.3166309775555636 1.0 0.7132254739218148 111 O00116,P98175,Q7RTS9,P02545,Q8N3R9,Q9Y366,Q9UBM7,P16278,Q9UHX1,Q8WVQ1,Q96L58,Q14739,Q13868,Q969N2,P55011,Q15056,Q15233,Q9Y448,P08236,O75431,P51798,O75530,O15287,O96028,P31749,Q9UQE7,Q9NX62,O75844,Q9UIG0 29 +Neoplasm of the thyroid gland 0.4086437243098969 1.000973671105634 0.3168395374539485 1.0 0.7133494818548929 29 P02545,P42892,Q15437 3 +Progressive sensorineural hearing impairment 0.4882104311951587 0.999133113372468 0.3177302120727376 1.0 0.7136911387820934 13 P03886,O60313,Q7Z406 3 +Short nose 0.338993488071469 0.9960894859096742 0.3192066679542977 1.0 0.7163756764314184 102 Q13045,Q5KU26,Q8N201,Q9UHX1,Q8NCH0,Q8WVQ1,Q96L58,Q9Y487,Q15392,P42892,Q969N2,O14936,P20700,Q15056,Q9UQE7,Q9NX62,Q01082,O60826,O75844,Q9UIG0 20 +Vertebral hypoplasia 0.4992012506479117 0.995974046139266 0.3192627557326162 1.0 0.7163756764314184 11 P16278,Q96HY6 2 +Poor eye contact 0.3671510414054078 0.9951276986924896 0.31967416061554 1.0 0.7166067652582799 45 P03886,Q9UHX1,O43676,Q96N67,O75251,Q01082,O75380,Q96RR1,Q96CU9 9 +Increased muscle fatiguability 0.6518574727172706 0.993034622860854 0.3206930820411715 1.0 0.7167618352127381 4 P53985 1 +Pulmonary fibrosis 0.4268036957508253 0.9926586565006584 0.3208763292472469 1.0 0.7167618352127381 21 P14174 1 +Cervical subluxation 0.672625547050687 0.992424249703892 0.3209906144877474 1.0 0.7167618352127381 3 P16278 1 +Abnormal circulating fatty acid concentration 0.4267674412531118 0.9924159486483396 0.3209946621621817 1.0 0.7167618352127381 21 P23786,Q9NUN5,O43772 3 +Milia 0.6725274725274736 0.9920452878983416 0.3211754338914612 1.0 0.7167618352127381 3 Q9H4L7,P50336 2 +Abnormality of hair pigmentation 0.4238523731823239 0.9902870007586708 0.3220338585184479 1.0 0.7167618352127381 23 Q86YV9,P02545,Q6PGP7,Q13126,Q9UBM7 5 +Shuffling gait 0.4980576774708416 0.9900602744254212 0.3221446589246963 1.0 0.7167618352127381 11 P02545,O75844,Q14203 3 +Secondary microcephaly 0.3412869716045271 0.9899831804831478 0.3221823401453587 1.0 0.7167618352127381 83 Q9HD42,Q9HC07,O75419,Q5KU26,Q9HC21,P11166,Q9UHX1,Q9Y487,Q13813,O14936,P50897,Q9BX67,Q96CU9,P55795,Q9UQE7,Q9NQT5,Q9BSJ2,P49770,Q9GZY8 19 +Abnormal metabolic brain imaging by mrs 0.4251516241535935 0.9897158694518404 0.3223130160827381 1.0 0.7167618352127381 22 P03886,Q9Y6N5,P07602,O75306,P00403 5 +Multiple joint contractures 0.4222003144214235 0.9896086350214206 0.3223654477285609 1.0 0.7167618352127381 24 P02545,Q96L58,O75844,P41440 4 +Abnormality of lysosomal metabolism 0.5902506455293434 0.989205046145332 0.3225628300222776 1.0 0.7168577097625652 6 P07602,Q9NWW5 2 +Abnormal circulating fatty acid anion concentration 0.4648084832736781 0.988392816016229 0.3229603044876299 1.0 0.71739796125909 15 Q9NUN5,O43772 2 +Abnormal circulating amino acid concentration 0.3488815200348849 0.9869354079948282 0.3236743046967651 1.0 0.7185161337844456 61 P03886,P20674,P22695,P55263,Q15046,P00846,Q9NUN5,Q7LG56,O14678,P25705,P23378,Q9P0J1,Q9BUB7,Q6PGP7,P41440,P32929,P05067 17 +Abnormality of the ovary 0.3397461224369094 0.9867342695098276 0.3237729253592918 1.0 0.7185161337844456 75 Q92878,Q9UIG0,P02545,Q5JTZ9,Q96RR1,Q13049,P20585,Q15056,O15078,Q03252,P48735,P35222,P31749,Q15051,P51809,Q15437,P31751,Q96RK4,O75844,P49770,Q01844 21 +Abnormal corpus striatum morphology 0.4274240868930237 0.9841146274132004 0.3250591556324873 1.0 0.7206822023970271 19 O75306,P00846,Q9NXR1,O95831 4 +Genu varum 0.4748064360908224 0.9829358852084468 0.3256389948774942 1.0 0.7210996940477843 14 Q7RTS9,Q8WVQ1,Q96HY6 3 +Sleep wake cycle disturbance 0.6490024351452679 0.9818522323857392 0.3261726514229401 1.0 0.7214136494977313 4 Q9UBM7,Q8N3U4 2 +Thin skin 0.4192802661843307 0.9812372266075856 0.3264757703666299 1.0 0.7214136494977313 25 Q96L58,P02545,Q13126,O75431,O75844 5 +Psoriasiform dermatitis 0.6187103648765195 0.979939929977344 0.3271157712315415 1.0 0.7224012110385278 5 P78536,Q9Y448 2 +Lethargy 0.3398988012516397 0.9766845848876088 0.3287253290273504 1.0 0.7242191675418543 92 O43772,Q8N3U4,Q9HC21,A2RRP1,P11166,P49748,O43676,P80404,O75251,O14678,Q9NXR1,Q96RR1,P03886,P20674,Q9Y3D3,P23786,Q7LG56,Q96CU9,Q9NWS8,P46783,O75306,O75380,P23378,Q9NUN5,P49770 25 +Moderately reduced visual acuity 0.6681891936974912 0.9752998238919384 0.3294115578202565 1.0 0.7242191675418543 3 O60313 1 +Narrow vertebral interpedicular distance 0.6681719840708477 0.9752334665536916 0.3294444649875996 1.0 0.7242191675418543 3 Q96HY6 1 +Vertebral arch anomaly 0.6681719840708477 0.9752334665536916 0.3294444649875996 1.0 0.7242191675418543 3 Q96HY6 1 +Abnormality of macular pigmentation 0.6466998911671724 0.9728442399867546 0.3306307214192192 1.0 0.7242191675418543 4 Q8NHS3,P35221 2 +Bell shaped thorax 0.6466979833704785 0.9728367802970268 0.3306344294952061 1.0 0.7242191675418543 4 Q96HY6 1 +Congenital hip dislocation 0.411892611691304 0.9726024526469944 0.3307509232041288 1.0 0.7242191675418543 27 Q9Y487,Q9UHX1,Q8TD16 3 +Rib fusion 0.4945903773959892 0.9721432172498772 0.3309793046200615 1.0 0.7242191675418543 11 O96028,O95155 2 +Lower limb spasticity 0.3396283954905375 0.971929180822359 0.331085781479973 1.0 0.7242191675418543 91 P31040,Q99720,P07942,P35637,O75298,Q92734,Q9Y619,Q7KZN9,P11166,O60313,O00400,Q8N0X7,O75787,O95831,Q5MNZ6,O75251,Q9H6K4,P55265,Q6DKK2,O00754,P07602,P00846,Q9Y4W6,P04062,Q96CU9,O75306,P42356 27 +Abnormality of exocrine pancreas physiology 0.4246801774081201 0.971661001663756 0.3312192240311444 1.0 0.7242191675418543 20 P14174 1 +Orthostatic hypotension 0.4727646480246744 0.9714948166941434 0.331301933018745 1.0 0.7242191675418543 14 P07602,O43681 2 +Micronodular cirrhosis 0.5529539816284321 0.970624932852716 0.3317350854461924 1.0 0.7242191675418543 7 P11717,O75787 2 +Abnormal endocardium morphology 0.4503482952709123 0.970540178858021 0.3317773076516643 1.0 0.7242191675418543 16 Q9NZ08,Q15056,P06280,Q9UIG0 4 +Corneal erosion 0.5858069957952624 0.9704998104584214 0.3317974193450845 1.0 0.7242191675418543 6 P39210 1 +Entropion 0.5175659576194084 0.9697591496559712 0.332166559282371 1.0 0.7243638283610397 9 O75844 1 +Multiple mitochondrial dna deletions 0.6458241137268305 0.9694205606088896 0.3323353979323453 1.0 0.7243638283610397 4 Q96RR1 1 +Nocturia 0.6458241137268305 0.9694205606088896 0.3323353979323453 1.0 0.7243638283610397 4 Q96RR1 1 +Tetraparesis 0.3774349722910209 0.9682531252706856 0.3329179687963159 1.0 0.7243638283610397 38 P07602,Q9UBX3,P00846,Q7RTS9,P50336 5 +Tracheal stenosis 0.6453139253508858 0.9674267354137503 0.3333307502248366 1.0 0.7248423005591089 4 Q9UBM7 1 +Abnormal urine ph 0.3513375107749887 0.9656940632920692 0.3341972910397137 1.0 0.7249064947606949 51 P03886,P49748,P23786,P00846,Q9NUN5,O43772,O14678,Q9NPF0,Q9HC21,P48735,Q8NFF5,P50336 12 +Abnormal systemic blood pressure 0.3362437460755152 0.9656321145615864 0.3342282995955754 1.0 0.7249064947606949 103 O43772,P02545,O00192,P06280,Q14203,P42892,Q9BUB7,Q13049,P50336,P03886,P20700,P07602,O15078,Q15056,O43707,Q15051,Q13423,O43681,Q96RK4,Q9NQH7,O75844 21 +Focal non motor seizure 0.4981221682516295 0.9647283868953812 0.3346808731257837 1.0 0.7249064947606949 10 Q05639,Q01105,Q96JM3,Q00610,P22466,P42356 6 +Abnormal t cell morphology 0.4373860801708362 0.963919951057424 0.3350860604181589 1.0 0.7249278038934751 17 P00813,Q9Y448,O75787 3 +Hypermetropia 0.3485679709248339 0.9632679017938888 0.3354130970325384 1.0 0.7249603078652122 58 A2RRP1,O00754,Q9UHX1,O95155,Q15056,Q9HD42,Q92878,O95714,Q9UIG0,P52732,Q71SY5,Q9Y366,Q969N2,Q5H8A4,O75175,Q96L73 16 +Hypocholesterolemia 0.515979535597434 0.9621251877637944 0.3359867231178897 1.0 0.725624440235946 9 P07602 1 +Abnormality of head blood vessel 0.4034208853119762 0.9620337213116128 0.3360326652437606 1.0 0.725624440235946 29 P03886,P00846,P10619,P07602 4 +Chronic oral candidiasis 0.6438093533101965 0.9615496972305636 0.3362758500467242 1.0 0.725664222089704 4 Q9Y448 1 +Generalized hirsutism 0.3953419442920421 0.960688108409526 0.3367090121469753 1.0 0.7260727514835241 31 Q9UQE7,Q15555,O95155,O15078,Q96JJ3,Q03252,P02545,Q96RK4,Q13049 9 +Nephropathy 0.4101510944181444 0.9600500227688687 0.3370300396447492 1.0 0.7260911424335418 27 P03886,Q14108,P06280,O15078 4 +Ureteral stenosis 0.5500233851220133 0.957655954198251 0.3382362739359743 1.0 0.7276345895652225 7 Q9UBM7,Q969N2 2 +Retinal coloboma 0.48043207703335 0.9569613159134328 0.3385867806952243 1.0 0.7276345895652225 13 Q9UHX1,O15078,Q10713,Q8N201,O14936 5 +Limb girdle muscular dystrophy 0.5328106016322667 0.9569082213429856 0.3386135812139614 1.0 0.7276345895652225 8 P50402,Q8WXH0,Q13642,P02545 4 +Abnormality of the voice 0.3044941800185313 0.9567648616154488 0.3386859516310687 1.0 0.7276345895652225 150 Q4J6C6,P02545,P06753,Q8N3R9,O00192,Q9NR77,Q8N0X7,Q9Y487,Q7Z406,P80404,O75787,Q14203,Q96RR1,Q6DKK2,P03886,P20700,P55011,Q15056,P00846,Q9H9S5,O75431,O75530,Q9UQE7,O75569,P25705,Q01082,Q96HY6,O75844,Q9UIG0 29 +Unilateral renal agenesis 0.4157084249950888 0.9562762369523214 0.3389326922108955 1.0 0.7278281981072233 25 Q9UHX1,P35606,Q9Y448,Q9UBM7,Q9NUN5 5 +Periventricular cysts 0.549423409104266 0.9550028637822738 0.3395762487365941 1.0 0.7288733616069065 7 O96028 1 +Joint stiffness 0.3423949557198119 0.9537711174289404 0.3401995123835875 1.0 0.7298740231055083 65 Q13045,O76024,P02545,P54802,Q14683,P16278,Q8TAA9,P15586,O95140,Q9NXR1,Q96L73,O00754,O95155,Q15056,Q9Y2U8,P08236,O75431,O75530,P48735,P31749,Q9UQE7,P50402,O75844,Q15042,Q9UIG0 25 +Generalized tonic seizure 0.4355538978448176 0.9524930991160055 0.3408469640843796 1.0 0.7306294889723285 17 Q05639,Q01105,Q96JM3,P27635,Q15046,Q00610,Q96N67,Q96T60,Q969N2,O14936 10 +Polydactyly 0.3469399074545806 0.9524553646972288 0.3408660925526163 1.0 0.7306294889723285 59 Q13045,Q9Y366,Q9UHX1,O95155,P98175,O15078,Q8WXW3,O60826,O75419,Q14739,Q9BRT2,Q96RK4,O00192,Q9UBM7,O96028,Q13049 16 +Spastic paraparesis 0.4195600039315149 0.9519248975059328 0.3411350716669346 1.0 0.7308689156460327 22 P31040,Q8N0X7,O75787,Q9Y4W6,Q9H6K4,P04062,Q9Y619,Q6DKK2 8 +High hypermetropia 0.4792799059794782 0.9507242565867764 0.3417443713326986 1.0 0.7314998127973517 13 Q71SY5,Q9Y366,O95155,Q15056 4 +Dilated cardiomyopathy 0.359950118537464 0.9497949112498628 0.3422164720773715 1.0 0.7319080808269035 46 P16278,P03886,O95155,P49748,P23786,P00846,Q7LG56,P02545,P06753,Q9H9S5,P09493,Q96RR1 12 +Cytochrome c oxidase negative muscle fibers 0.5131791643245955 0.948661693642445 0.3427927025821766 1.0 0.7319525359356849 9 Q96RR1,Q9Y2R0 2 +Hydrocephalus 0.3377888015498463 0.9485116944878976 0.3428690221944546 1.0 0.7319525359356849 83 P07942,Q8N3U4,O00192,Q9UBM7,P11166,O60566,Q9Y2V7,Q96L58,Q15392,Q10713,O95140,Q12768,O00754,O15078,P23786,Q8WXW3,O43505,Q9H9S5,P08236,P51798,O15287,O96028,P04062,P35222,P31749,Q8NAT1,Q01082,P15291,Q93009,O60826,Q14738 31 +Optic neuropathy 0.4051806534068691 0.948448968236076 0.3429009405491685 1.0 0.7319525359356849 28 P03886,O43676,P00846,O75380,Q96CU9 5 +Tetraplegia 0.4786385113622169 0.9472533872455444 0.3435096768951187 1.0 0.7326799596911464 13 O43681,O95831 2 +Spastic paraparetic gait 0.6104302400490984 0.946481996805377 0.3439028005023177 1.0 0.7330808779515001 5 Q15043,O75787,Q01433 3 +Abnormality of the chin 0.337541489480729 0.9454128955766298 0.3444481211457399 1.0 0.7335703111660191 90 P16278,P20700,O00754,P55011,Q9UHX1,O95155,Q15056,Q7RTS9,P52732,Q71SY5,P02545,Q9Y448,Q01082,Q96EK5,O75530,O75844,P11274,Q9UIG0 18 +Simplified gyral pattern 0.3844819583775686 0.9441655838466462 0.3450850393152707 1.0 0.7340597120810716 33 P20700,Q86XL3,P35606,P52732,Q03252,Q5KU26,Q9Y3C6,O14936 8 +Sarcoma 0.3440760860867012 0.9441217666509742 0.3451074274550203 1.0 0.7340597120810716 62 P31040,O60566,Q96JJ3,P46783,Q15392,P35222,Q15437,P02545,Q01082,Q13126,P48735,P31749,Q01844 13 +Hypopigmented macule 0.6391865897224565 0.9435202900640672 0.3454148420132039 1.0 0.7340597120810716 4 Q15149,Q15233,Q9NP58 3 +Narrow mouth 0.3364593338283728 0.9432735950885742 0.3455409782299017 1.0 0.7340597120810716 77 O75419,P02545,Q8N3R9,O00192,Q8NCH0,Q8WVQ1,Q9Y487,Q15392,Q6PGP7,P55011,O95155,Q15046,Q15233,O75431,P11274,P31749,Q15555,Q9NX62,O75844,O75175 20 +Raynaud phenomenon 0.5466532617110781 0.9427626358403188 0.3458023272879869 1.0 0.7340993215656807 7 P02545,O75844 2 +Horizontal eyebrow 0.5789895792166915 0.941872576613916 0.3462578818139106 1.0 0.7347307656571884 6 P78536,O95155 2 +Skin vesicle 0.4831061163293857 0.9402800063189078 0.3470739524131137 1.0 0.7357595206590012 12 P16615 1 +Methylmalonic acidemia 0.5291229315690953 0.9399803212356674 0.3472276548469315 1.0 0.7357595206590012 8 Q9NUN5 1 +Stereotypy 0.3355798028205671 0.9383087538344368 0.3480857623883413 1.0 0.7357595206590012 70 Q05639,Q13045,Q9UNW9,Q01105,Q9H2P0,Q96N67,Q71SY5,O14646,Q14683,P67870,P11166,Q9UHX1,Q96JM3,O95714,P20700,P55011,O95155,Q8NB90,P15311,Q9UBB6,O96028,P55795,Q96N66,Q14139,Q00610,Q06787,P61916,Q6PJT7,Q01082,Q9NUQ7,Q14738 31 +Abnormality of the zygomatic bone 0.3358007106863549 0.9382647924004888 0.3481083483909641 1.0 0.7357595206590012 76 O00754,O60566,Q8WVQ1,Q15056,Q15233,Q96L58,Q9HC07,Q9Y487,Q14739,P02545,O95831,O00192,Q969N2,P11274,O75175,Q9UIG0 16 +Aplasia hypoplasia of toe 0.3738923153479562 0.938149327538182 0.3481676750439302 1.0 0.7357595206590012 38 Q9UHX1,Q9NX62,P02545,Q8N3R9,P00813,O96028 6 +X linked recessive inheritance 0.3459111537773358 0.9358750528933172 0.3493375230872797 1.0 0.7370659839565817 58 P26038,O15344,P98175,Q15233,O14936,Q8IWS0,O75787,O95831,O75027,O60826,O95239,P06280,P29372 13 +Hemoglobinuria 0.6371633508625192 0.9356430904044684 0.3494569807234624 1.0 0.7370659839565817 4 Q969N2,O14936 2 +Abnormality of the lymph nodes 0.3667699861603845 0.9351519868386866 0.3497099781716075 1.0 0.7370659839565817 42 P00813,P28070,P14174 3 +Abnormality of the posterior pituitary 0.5102904583126169 0.9347906819115788 0.3498961826142068 1.0 0.7370659839565817 9 Q9UHX1,P31749,O76024,P42356,P35222 5 +Nevus 0.3782716426590087 0.9317967318001718 0.3514415839649567 1.0 0.7386472368544341 34 Q9UQE7,Q9UHX1,Q15056,Q15437,Q71SY5,Q01082,O75530,Q9UIG0 8 +Preauricular skin tag 0.4193773148230552 0.9314070994951352 0.3516430198351581 1.0 0.7387364887766635 19 O96028 1 +Profound hearing impairment 0.5761571930592837 0.9300063967875942 0.3523677724926279 1.0 0.7397340841170076 6 Q9NR77,P55011 2 +Renal tubular atrophy 0.6356801916232491 0.9298741436491208 0.352436251825921 1.0 0.7397340841170076 4 Q9NQH7 1 +Recurrent infection of the gastrointestinal tract 0.5759427536721995 0.929108706474794 0.3528327528523163 1.0 0.740042900489832 6 P78536 1 +Abnormal elasticity of skin 0.333489350869001 0.9286933673571534 0.3530480190553007 1.0 0.740042900489832 71 O00754,Q9Y3D3,Q15555,Q9UHX1,Q8NCH0,Q15056,Q96L58,Q9Y487,O75787,P02545,Q13126,O75530,O75844,Q9UIG0 14 +Aplasia hypoplasia involving bones of the upper limbs 0.3036954643229803 0.9286680596981408 0.3530611384518953 1.0 0.740042900489832 152 O00116,P98175,Q7RTS9,P02545,Q9Y366,Q9UBM7,Q96EK5,Q9UHX1,Q8WVQ1,Q96L58,O95831,Q14739,Q969N2,O14936,Q03252,Q9Y448,P51798,O96028,P11274,Q9UQE7,Q15555,Q9NX62,Q13555,P46783,O60826,O75844 26 +Color vision defect 0.4542444653268404 0.9271972673196952 0.3538241214044126 1.0 0.7408184630543381 15 Q13432,A2RRP1,O60313,Q9Y4W6,Q6P4Q7,Q9H6K4,Q9H061 7 +Abnormal leukocyte physiology 0.3333122541997509 0.9266734490649006 0.354096106929632 1.0 0.7408755555614588 71 Q14108,P02786,P28070,Q969N2,O75787,P14174,P02545,Q9Y448,O00192,P00813,P78536 11 +Cerebral calcification 0.3707999725150309 0.9248664367160538 0.3550353870559348 1.0 0.7416805703784184 39 P03886,P11166,O60313,O00584,P23786,P05067,Q16625,P00403 8 +Hypopigmentation of the fundus 0.6547581064640371 0.923697773756519 0.3556436915314647 1.0 0.7424421538844189 3 Q9Y619 1 +Abnormality of pancreas physiology 0.3496699215967728 0.9222102595084726 0.3564189126409154 1.0 0.7435955872527229 49 P03886,Q9UHX1,Q9NZ08,P53985,P14174,P02545,Q9NQH7 7 +Periorbital edema 0.4015673063550393 0.922023648963443 0.3565162402408148 1.0 0.7435955872527229 28 Q15056,P28070,Q14331,O43707,Q01082,Q9Y448,Q8N1F7 7 +Unexplained fevers 0.5418229448199265 0.9214582464231126 0.35681123081274 1.0 0.7438769805234647 7 P07602 1 +Breech presentation 0.5073910231525844 0.9208869626491244 0.3571094459684565 1.0 0.7441648409934607 9 Q9UBM7,O60313,O75718,P06753 4 +Absent septum pellucidum 0.3717981583978442 0.92037772867494 0.3573754028704128 1.0 0.7443852519671933 38 Q96N66,Q14139,P55011,O43505,Q15392,Q8N3U4,Q71SY5,Q9UBB6,Q8NAT1,Q9H9S5,O96028,Q9NUQ7 12 +Osteolysis 0.4010191463002538 0.9180187305524534 0.3586090598633586 1.0 0.7459517910407465 28 O00754,O60566,Q14108,Q96JJ3,O75844,P02545,O75431,P04062,P48735 9 +Incomplete penetrance 0.3809011464787834 0.915523948951286 0.3599166357464562 1.0 0.747417290358339 33 P03886,P11166,O60313,Q8WWY3,P00846,Q9NWH9,P52732,O43707,P42224,P35222,P49792 11 +Abnormality of vitamin b metabolism 0.441165998836933 0.9154471430108344 0.3599569390621826 1.0 0.747417290358339 16 O14678,P41440,Q9NUN5 3 +B lymphocytopenia 0.506101040377787 0.9147074866155304 0.3603452130114506 1.0 0.7478893277642746 9 P00813,Q9Y448 2 +Cerebellar cyst 0.3511786910706613 0.9124075000338572 0.3615542428515366 1.0 0.749331931045955 48 O60826,O15078,P23786,Q9Y487,O43505,P15291,Q9UBM7 7 +Abnormal venous morphology 0.3925643939315824 0.9089341674925916 0.3633848769293384 1.0 0.7505108991513936 30 P02545,Q9Y487,Q71SY5,P98175 4 +Middle age onset 0.4868399280826397 0.9079483661954564 0.3639055022780513 1.0 0.7510140107798584 10 P07602 1 +Bulbous nose 0.3507008536876693 0.9078609327101812 0.3639517005113495 1.0 0.7510140107798584 48 Q9UQE7,P23786,Q96N67,Q01082,Q9BSJ2,P42892,O75431,O00192,Q96EK5 9 +Thoracic hypoplasia 0.3797754597951791 0.906531002109428 0.364654863289334 1.0 0.7517074076571768 33 Q9UHX1,Q8WVQ1,O75718,Q14739,P02545,P06753,Q96HY6,Q9Y366 8 +Abnormal brain lactate level by mrs 0.4505649908460576 0.9059440698540824 0.3649654567367253 1.0 0.7517074076571768 15 P03886,Q9Y6N5,O75306,P00403 4 +Muscle fiber inclusion bodies 0.5041935829912629 0.9055776590742168 0.3651594381463803 1.0 0.7517074076571768 9 O43676,P07196 2 +Mottled pigmentation 0.6497316797636947 0.9044909759877338 0.3657351172400167 1.0 0.7523555067792641 3 O75844 1 +Hand polydactyly 0.3627957033139315 0.8999641769617467 0.3681393149650078 1.0 0.7556287087643072 42 Q13045,Q9UHX1,O60826,P98175,O15078,Q8WXW3,Q14739,Q96RK4,O00192,Q9UBM7,O96028,Q13049 12 +Schwannoma 0.6484021264560018 0.8994209733205808 0.3684284718974406 1.0 0.7557211216876244 3 Q15046 1 +Cervical myelopathy 0.6481218715869621 0.8983528478441309 0.3689974661306692 1.0 0.7557211216876244 3 P16278 1 +Abnormal sensory nerve conduction velocity 0.5361799978965257 0.8966382559876471 0.369911977442706 1.0 0.756347456089789 7 Q9NR77,O15269,Q7LG56 3 +Accessory spleen 0.5021798372208818 0.8959492851239196 0.3702798499256015 1.0 0.756347456089789 9 O96028 1 +Corneal dystrophy 0.5678490723261279 0.8953033555423563 0.3706249470447007 1.0 0.7563874083955751 6 Q13868,P06280 2 +Pulmonary embolism 0.597182231813725 0.893246986124686 0.3717249210860933 1.0 0.757140897271489 5 Q9NZ08 1 +Ectopic calcification 0.3382336366963493 0.8902808628538494 0.3733150942651464 1.0 0.7588780590770496 63 O00116,P11166,O60313,P03886,Q15046,O00584,P23786,Q14739,P02545,P08236,O75431,Q9UBM7,O75844,P05067,Q16625,P00403 16 +Facial edema 0.3935639048548641 0.8887747073192982 0.3741241715687633 1.0 0.7598410014860504 29 Q15056,P28070,Q14331,O43707,Q01082,Q9Y448,Q8N1F7 7 +Long toe 0.4829585125000277 0.8884860967546816 0.3742793312678221 1.0 0.7598410014860504 10 Q9UHX1 1 +Lower limb muscle weakness 0.3553899307797682 0.8871612604938314 0.3749920859833771 1.0 0.7606234061827818 45 Q9NR77,Q8N0X7,Q7Z406,P00846,P02545,P06753,O75298,P07196,Q00796 9 +High pitched voice 0.4822568504844531 0.8849722596993175 0.3761715930773959 1.0 0.7616860100351455 10 O75844,O75431 2 +Abnormal esophagus physiology 0.3352720174029616 0.8831307983688659 0.3771656055954773 1.0 0.7630337697876287 241 Q13045,Q99720,Q14108,O15344,O15118,Q9HD42,Q8IZA0,Q9UIG0,Q8WVM7,P06753,O00192,Q9UBM7,P06280,P05067,Q9NR77,Q9UHX1,P49748,Q8N0X7,P15586,Q14203,Q14739,O14678,Q6ZXV5,Q96RR1,Q969N2,P29372,P03886,P20700,P55011,O95155,P07602,Q15056,P00846,Q7LG56,Q96F07,Q9Y448,O96028,P48735,Q9UQE7,P61916,O75569,O75306,Q14331,Q93009,O60826,Q8NFF5,Q9UEY8,Q9GZY8 48 +Stomatitis 0.4356358253716921 0.882375270023913 0.3775739044862234 1.0 0.7633653966269228 16 Q9NUN5 1 +Supernumerary bones of the axial skeleton 0.5941174839420804 0.8809912223033891 0.3783225709473083 1.0 0.7636913320787878 5 Q9UHX1 1 +Abnormal nipple morphology 0.3388122950051228 0.8809481799913932 0.3783458682705574 1.0 0.7636913320787878 61 Q9UQE7,Q15555,O60826,P23786,O14678,Q9Y448,P10586,O75530,O96028,Q9UBM7,Q969N2,Q96EK5,Q5H8A4 13 +Decreased muscle mass 0.4076003464284097 0.8794946467744015 0.3791331343873869 1.0 0.7639027565024252 23 Q8NCH0,P04066,Q9Y487,Q7LG56,O96028,P31749 6 +Diminished movement 0.4098362112842512 0.8794267303787872 0.3791699440568727 1.0 0.7639027565024252 21 Q9Y3D3,P51114,Q7LG56,Q14203,O95831,P06753,Q96RR1 7 +Abnormal basal ganglia mri signal intensity 0.3717847254815863 0.8789589820014363 0.3794235163854569 1.0 0.763943275841949 34 P16278,P03886,P00846,O75251,Q7KZN9,Q96CU9,Q9GZY8 7 +Sound sensitivity 0.4807547256201809 0.8774546042244857 0.380239765580562 1.0 0.7640763489606686 10 Q9UIG0,Q15056,Q9GZY8 3 +Scaling skin 0.4982632089521208 0.8772543426559477 0.3803485053472037 1.0 0.7640763489606686 9 P02545,O75844,P78536 3 +Posterior pharyngeal cleft 0.6421998954294235 0.8758309426584768 0.38112194587405 1.0 0.7640763489606686 3 O15344 1 +Broad long bones 0.3616084551819307 0.8738612509150882 0.3821938191232397 1.0 0.7655408092524546 41 Q9UHX1,Q96L58,Q71SY5,Q13868,Q9Y448,Q8N3R9,O75530,O14936 8 +Gingival overgrowth 0.3914060473767048 0.8727888376341427 0.3827781848960709 1.0 0.7656747280887446 29 P16278,O00754,P20700,Q15056,Q14739,P08236,Q9UBM7 7 +Generalized muscle weakness 0.3699542455063473 0.8727035080362872 0.3828247051174256 1.0 0.7656747280887446 35 P31040,Q68CQ7,P35637,Q15165,Q14203,O95831,Q5JTZ9,P06753,Q9H9S5,P10253,P49792 11 +Irregular menstruation 0.5920382660804103 0.8726905001008838 0.3828317971232096 1.0 0.7656747280887446 5 Q06787,P02545,O00170 3 +Venous thrombosis 0.4339134941483551 0.8720951687501785 0.3831564615634999 1.0 0.7656871150501672 16 Q9NZ08,Q9NWH9,P52732,P48735,P31749 5 +Generalized joint laxity 0.4546472673112067 0.8703899682517273 0.3840873270544307 1.0 0.7670192560472451 14 Q9Y487,Q9UHX1 2 +Aplasia hypoplasia of the vagina 0.639935445247404 0.8672442946935321 0.385808171242568 1.0 0.7684757272897562 3 P51809 1 +Osteolysis involving bones of the upper limbs 0.4960968366347078 0.8669328203045443 0.3859788195026699 1.0 0.7684848218632848 9 O75844,O75431 2 +Elevated hemoglobin a1c 0.6397531777584726 0.8665537787980924 0.3861865480958131 1.0 0.7685691173452863 3 O75431 1 +Tongue fasciculations 0.468127494894941 0.8615372827911607 0.3889421963761166 1.0 0.7724745103683782 12 P51114,Q9BQT8,Q9NWS8,O95831 4 +Abnormal platelet morphology 0.5595657982950093 0.8608761221061292 0.3893062739844555 1.0 0.7724879006100521 6 P12814 1 +Abnormal tissue metabolite concentration 0.4527131785111071 0.8596517811986919 0.3899810221554847 1.0 0.7727023975012073 14 P07602,O43681 2 +Abnormal metacarpal morphology 0.3671930007565511 0.8594586349514881 0.3900875321396269 1.0 0.7727023975012073 36 P16278,Q8WVQ1,Q9NX62,Q96L58,Q7RTS9,Q14739,Q9Y448,P08236,Q9Y366 9 +Abnormal anterior chamber morphology 0.5592216017346223 0.8594496359272735 0.3900924950587114 1.0 0.7727023975012073 6 Q96JJ3 1 +Narrow forehead 0.3405079011413371 0.8585763042818763 0.3905743159128039 1.0 0.7733271606505325 50 A2RRP1,P20700,P55011,Q9UHX1,O95714,Q13555,O75787,Q96N67,Q01082,Q9BSJ2,Q9UBM7,Q969N2,Q15042,Q14738 14 +Cough 0.392449924824657 0.8555702506269722 0.3922355311188701 1.0 0.7762855677637944 28 Q9NR77 1 +Aganglionic megacolon 0.4037248843459582 0.8532097554640523 0.3935429944320905 1.0 0.7778793258723626 23 O15078,Q8WXW3,O15287,Q10713,P42892,O00192,Q9UBM7,Q96EK5 8 +Brittle hair 0.4413463606802304 0.8528742235637744 0.3937290574389351 1.0 0.777916211700141 15 Q9Y487 1 +Methylmalonic aciduria 0.4930314863938694 0.8523528625057469 0.39401827422415 1.0 0.7781567872161604 9 O14678,Q9NUN5 2 +Gastroesophageal reflux 0.3042853562178016 0.8517147011818909 0.3943724590805624 1.0 0.7782272528119542 136 Q05639,Q13045,Q01105,O15344,Q9HD42,Q8IZA0,Q8N3U4,Q8WVM7,O00192,Q9UBM7,Q9UHX1,P49748,Q14739,O14678,Q6ZXV5,Q96RR1,Q969N2,P29372,P55011,O95155,P07602,Q15233,Q15056,P00846,Q7LG56,Q96F07,Q9Y448,O96028,P55795,Q9UQE7,Q93009,P42356,O60826,Q9UIG0 34 +Elevated urinary delta aminolevulinic acid 0.6154430310360576 0.8516851014745641 0.3943888918382079 1.0 0.7782272528119542 4 P50336 1 +Broad nasal tip 0.3384909012940078 0.8508229166153201 0.3948677295081957 1.0 0.7787147579717466 56 P16278,Q9UHX1,Q9Y487,Q96N67,O95831,P52732,Q13868,Q9Y448,P10586 9 +Atrophy degeneration involving the corticospinal tracts 0.4303126771496917 0.8506368795648057 0.3949710963071673 1.0 0.7787147579717466 16 O00400,Q15056,P35637,P00846,Q14203,O75298,Q9UIG0 7 +Somatic mutation 0.3532651084987593 0.8491326355719678 0.3958074923959009 1.0 0.7797021692088816 44 P11717,P20585,O60566,O75330,O75533,Q9NWH9,P35222,P11274,P00813,Q969N2,Q9Y6D9,P31749,Q01844 13 +Transposition of the great arteries 0.5557072481793361 0.844904603347888 0.3981641040688948 1.0 0.7830724056065708 6 O75844 1 +Axial muscle weakness 0.5553285301477078 0.8433393878530762 0.3990386601625975 1.0 0.7843084191778144 6 P02545,Q8TD16 2 +Supernumerary spleens 0.4693118456252683 0.8423481951885033 0.3995930813903738 1.0 0.7843084191778144 11 O96028 1 +Abnormal circulating carboxylic acid concentration 0.3269030506234736 0.8421495917525077 0.3997042254395331 1.0 0.7843084191778144 102 P03886,P11166,P22695,P55263,P23786,P00846,P32929,P48735,Q14739,O14678,P25705,Q01082,Q9BUB7,P00390,P41440,Q9NUN5,P05067,O14936 18 +Abnormal bleeding 0.3203006069392879 0.8405518206648976 0.4005990592170867 1.0 0.7844853890357362 116 Q14108,P02545,Q13126,O00192,P05067,Q16625,P35579,Q9UHX1,Q8NCH0,Q96L58,Q9Y487,Q96JJ3,Q14739,Q6ZXV5,Q9NXR1,P12814,P23786,O15484,P51798,P31749,Q9NZ08,Q86YV9,P11117,O75844,Q9NUN5 25 +Cerebral white matter atrophy 0.4046687227825339 0.8397599600261743 0.4010429875312247 1.0 0.7850239103022751 20 O75503,P20700,O00754,Q93009 4 +Aplasia hypoplasia of the extremities 0.3177803018435239 0.8387256128161293 0.4016233020316411 1.0 0.7854841639942372 198 O00116,P98175,Q7RTS9,P02545,Q8N3R9,Q9Y366,Q9UBM7,Q96EK5,Q9UHX1,Q8WVQ1,Q8N0X7,Q96L58,Q15392,O75718,O95831,Q14739,P00813,Q969N2,O14936,P55011,O95155,Q03252,Q9Y448,O75431,P51798,O96028,P48735,P11274,Q9UQE7,Q15555,Q9NX62,Q13555,Q9NWH9,P46783,Q96HY6,O60826,O75844 37 +Central hypothyroidism 0.4684522769765638 0.8379676331256318 0.402048881928404 1.0 0.7854841639942372 11 P27635,P31749,Q8N3U4,P35222,O14654,Q14683 6 +Periventricular heterotopia 0.4684251050277966 0.8378292013766433 0.4021266358653224 1.0 0.7854841639942372 11 Q9UBM7,P11177,Q6ZXV5,Q9NXR1,P19022 5 +Long penis 0.6321428571428584 0.8378097356305092 0.4021375700515124 1.0 0.7854841639942372 3 O14802,P31749 2 +Delayed puberty 0.3367864480105802 0.8375343123671756 0.4022922983228501 1.0 0.7854841639942372 57 Q13045,Q14108,Q8IWS0,O76024,P02545,P42224,P06280,O95714,P57740,Q15233,P04062,P35222,Q9UQE7,P27635,P51809,Q01082,Q8IY37,O75844,Q15042,Q9UJS0 20 +Gangrene 0.4631218857635347 0.8353742031142672 0.4035070498200053 1.0 0.7865363295700112 12 Q9NZ08 1 +Cutaneous syndactyly of toes 0.6310439560439574 0.833673847052803 0.4044647994455412 1.0 0.7877401186183697 3 P27635,Q9H4L7 2 +Vertebral segmentation defect 0.3658591661982923 0.830890558992043 0.4060354575398708 1.0 0.7889748318394088 34 Q9UHX1,Q15056,Q8N3U4,Q9H9S5,O96028,O60826,Q9UIG0 7 +Myoclonic spasms 0.5051151504211866 0.8306105089140369 0.4061936961142671 1.0 0.7889748318394088 8 P00846,P31749 2 +Undetectable light and dark adapted electroretinogram 0.5814184016912395 0.8304837377039435 0.4062653386055501 1.0 0.7889748318394088 5 P00846 1 +Medial flaring of the eyebrow 0.5210329825922775 0.8304449979699451 0.4062872331809135 1.0 0.7889748318394088 7 Q13049,O15078 2 +Specific learning disability 0.3247403320602325 0.8291437687060416 0.407023059381514 1.0 0.7892388074668546 71 Q8N3U4,O75419,O00192,Q9Y619,Q96EK5,P11166,Q5THJ4,Q8N0X7,O95714,Q10713,Q9H6K4,Q9BPX6,Q96RR1,Q8WYQ5,P00403,P03886,O00754,Q96L73,Q9Y2U8,P52732,O43505,Q9H9S5,P62266,Q8NAT1,Q01082,P42356 26 +Depression 0.3194266588268273 0.8287032244841664 0.4072723607285382 1.0 0.7892388074668546 116 P31040,P35637,Q8N3U4,Q71SY5,O00192,P06280,P11166,Q14203,Q5JTZ9,Q96RR1,Q6DKK2,P00403,P03886,P20700,O00754,P55011,P07602,Q15056,P50897,Q7LG56,Q9Y4W6,Q9UBB6,P04062,P11274,Q96N66,Q14139,Q68CQ7,P54277,Q6PJT7,Q15165,Q01082,O43681,Q9NWW5,Q9NUQ7,Q9UIG0 35 +Aplasia hypoplasia of the clavicles 0.4561796080131734 0.8264086140496634 0.4085723386258415 1.0 0.7900469447604133 13 O75419,P02545,O75431,Q9Y619,O75844 5 +Germinoma 0.6087748728715802 0.8261668348209003 0.4087094588345241 1.0 0.7900469447604133 4 P31749 1 +Paranoia 0.5506959981595074 0.8242296865139888 0.4098090621137698 1.0 0.790834960322066 6 P50336 1 +Increased circulating gonadotropin level 0.4869468149310816 0.8235041736724301 0.410221344720767 1.0 0.790834960322066 9 Q8IY37,P57740,P51809 3 +Vertebral wedging 0.6282967032967045 0.8233510510901693 0.4103083902165916 1.0 0.790834960322066 3 Q96AY3,Q8WVQ1 2 +Weak voice 0.5501949199942666 0.8221668108009895 0.4109819651443991 1.0 0.7913346018446393 6 P04062,O75787,Q14203 3 +Recurrent pneumonia 0.4002142195312477 0.8219350508555754 0.4111138628808037 1.0 0.7913346018446393 22 Q71SY5,P00813 2 +Decreased circulating level of specific antibody 0.4695367030629594 0.8215407656815866 0.4113383136718607 1.0 0.7913346018446393 10 P00813 1 +Abnormality of earlobe 0.3732281159699033 0.8212250605735834 0.4115180843945947 1.0 0.7913346018446393 32 P98175,Q15392,Q96N67,P10586,P11274 5 +Abnormal middle phalanx morphology of the hand 0.5030090976523688 0.821099921067081 0.4115893549942959 1.0 0.7913346018446393 8 P02545,Q9Y448,Q9UHX1,Q15233 4 +Muscle fibrillation 0.4355834515577419 0.8198523826489069 0.4123002648891156 1.0 0.7923735859965758 15 P51114,Q9NQT5,Q9BQT8,O95831,Q92734,Q9NWS8 6 +Hemivertebrae 0.4546079955371592 0.8180143721667146 0.4133489807117909 1.0 0.7930770905729531 13 O60826,Q9Y619,Q9UHX1,Q8N3U4 4 +Red green dyschromatopsia 0.6266072875176116 0.8170153478640043 0.4139196571927224 1.0 0.7933446407847858 3 O60313 1 +Mask like facies 0.4347654943105929 0.8151764148622437 0.4149713361242637 1.0 0.7933446407847858 15 Q9H9S5,Q13049,O75787,Q14203 4 +Aplasia hypoplasia of the 5th finger 0.4347554120959293 0.8151187964197177 0.4150043133942884 1.0 0.7933446407847858 15 Q12824,Q9UQE7,Q9UHX1,P51532,Q68CP9,O75147,Q8TAQ2,O00443 8 +Buphthalmos 0.6058197629208988 0.8149021601270965 0.4151283166081296 1.0 0.7933446407847858 4 Q9H9S5,P31749 2 +Abnormal vena cava morphology 0.463309358698426 0.8118150220570137 0.4168977809780494 1.0 0.795288993516008 11 P98175 1 +Mandibular aplasia 0.575767082765319 0.8081649801053008 0.4189956146272804 1.0 0.797754819572115 5 P53701,Q9Y619,O75419 3 +Abnormal oral physiology 0.3324157456496693 0.8077744861351694 0.4192204151915439 1.0 0.797754819572115 60 Q9NR77,P55795,P55011,Q15233,Q8N0X7,Q68CQ7,P35637,Q02241,O75787,P15586,Q14739,Q14203,P06753,Q03252,Q15165,Q01082,P42356,Q14738 18 +Unusual infection by anatomical site 0.4120827383032874 0.8070072566748394 0.4196623023499852 1.0 0.798268816627254 17 Q9BUB7,P02786,Q9NZ08,Q14739 4 +Short chin 0.4658360375841279 0.8031948851275791 0.4218621014014778 1.0 0.800368326797775 10 O75844 1 +Abnormal shoulder morphology 0.3623498839928049 0.8025312233206285 0.4222457345646511 1.0 0.800368326797775 34 P55011,Q15056,Q7RTS9,P02545,Q6ZXV5,Q8N3R9,O75175,Q9UIG0 8 +Pectus excavatum 0.3254217739871866 0.8024618974143851 0.4222858205566426 1.0 0.800368326797775 83 O00754,Q9UQE7,Q15555,Q9UHX1,Q8NCH0,P98175,Q15056,Q96L58,Q9Y487,Q9NWH9,Q15437,O75718,P02545,P06753,O75431,Q9Y366,Q969N2,Q9UIG0 18 +Full cheeks 0.3549494601973124 0.8022098510337814 0.422431578939584 1.0 0.800368326797775 40 Q9UHX1,O15078,Q96JJ3,P52732,P02545,O75431,Q9Y366 7 +Inflammatory abnormality of the eye 0.34801388553942 0.8018936554158792 0.4226144764977206 1.0 0.800368326797775 44 P02786,P28070,Q9NZ08,Q14739,P14174,O15484,P78536 7 +Radioulnar synostosis 0.397178386011307 0.8016842430203243 0.4227356327894656 1.0 0.800368326797775 22 Q9UQE7,Q15056,Q8WVQ1,Q96L58,O96028 5 +Hemorrhage of the eye 0.4565960558614889 0.8014046919743448 0.4228973997506902 1.0 0.800368326797775 12 Q9Y487,O15484,P35222,P49792 4 +Emg neuropathic changes 0.3907854860130215 0.8012186419784393 0.4230050808296397 1.0 0.800368326797775 26 Q9NR77,P07602,P39210,O43681 4 +Exostoses 0.5449190013609468 0.8004979616472155 0.4234223440723665 1.0 0.8005450068444153 6 P48735 1 +Colorectal polyposis 0.4610174805234372 0.8001936827158904 0.4235985893673852 1.0 0.8005450068444153 11 P20585,Q15437 2 +Stillbirth 0.4650850688242607 0.7994786535718881 0.4240129194654543 1.0 0.8009707466487668 10 P02545,O75844,Q14739 3 +Severely reduced visual acuity 0.6011399872379739 0.7971221031373062 0.425380120604395 1.0 0.8028790750310253 4 O15078 1 +Abnormal circulating free fatty acid concentration 0.6010667141884698 0.7968443066175822 0.4255414593934614 1.0 0.8028790750310253 4 O75431 1 +Thoracic kyphoscoliosis 0.5438162801077051 0.7959812186175915 0.4260429518911368 1.0 0.8031730618410194 6 O75844 1 +Gastroparesis 0.4803862993440698 0.7925512011639685 0.4280393495980394 1.0 0.8049772794747428 9 Q9BUB7,Q96RR1 2 +Bilateral talipes equinovarus 0.5716171376441151 0.7918441499218319 0.4284515555890444 1.0 0.8054265286497936 5 Q15392 1 +Hypopigmented skin patches 0.3803758248618054 0.7914592737383557 0.4286760327815979 1.0 0.8055226544019756 29 P07602,O15287,Q8IZA0,Q15437,O00192 5 +Multiple prenatal fractures 0.4957352528413972 0.7883783739181691 0.430475416681082 1.0 0.8075798951240115 8 P06753,O75718 2 +Myopia 0.3175953052360248 0.788335919155393 0.4305002427497202 1.0 0.8075798951240115 114 Q13045,P98175,Q9HD42,O75419,Q9Y366,A2RRP1,Q9UHX1,Q8NCH0,Q8WVQ1,Q96L58,Q9Y487,Q13868,Q969N2,O14936,O00754,Q15056,Q15233,P52732,P30533,Q9H9S5,O75530,Q9UQE7,Q15555,Q13555,Q15437,Q93009,Q9UIG0 27 +Abnormal adipose tissue morphology 0.3286173787897957 0.7880973531351465 0.4306397633133851 1.0 0.8075798951240115 63 P04066,Q9Y487,P28070,P52732,Q03252,P02545,Q15437,O75431,P09493,O75844 10 +Severe global developmental delay 0.3231719688291282 0.7866459885878783 0.4314891300023136 1.0 0.8086174131505867 78 P03886,P07942,P55263,O00584,P00846,Q7RTS9,Q71SY5 7 +Abnormal mitochondria in muscle tissue 0.3858638772969822 0.7862089863046638 0.4317450623051959 1.0 0.8086174131505867 27 P03886,O43676,O75306,O75251,O75380,Q96CU9,P00403 7 +Loss of eyelashes 0.6181292857465537 0.7853693123817512 0.4322370678429217 1.0 0.8086174131505867 3 O75844 1 +Pelvic kidney 0.4786780153394515 0.7845195513113729 0.4327353143613957 1.0 0.8092237448037849 9 Q9UHX1,Q15056 2 +Abnormality of secondary sexual hair 0.494616806752931 0.7833653720329532 0.4334125847078547 1.0 0.8101642321550285 8 P57740,P51809 2 +Impaired smooth pursuit 0.4290083358881632 0.7823500282822422 0.4340088931455832 1.0 0.8104338519757445 15 O00754,P41440,P11177 3 +Progressive microcephaly 0.3350851864751313 0.7822289716163444 0.4340800209958313 1.0 0.8104338519757445 49 P11166,P50897,Q9Y487,O75419,Q5KU26,Q9BSJ2,Q13813,O14936 8 +Female reproductive system neoplasm 0.3946651211417692 0.7791068638241856 0.4359167671982948 1.0 0.8131633956035824 21 Q15437,P20585,O60566,P31749 4 +Subcortical band heterotopia 0.5679768963467543 0.7775785394299246 0.4368175166811552 1.0 0.8132803447468182 5 P07942 1 +Capillary hemangioma 0.4931387802458616 0.7767485976390692 0.437307108781765 1.0 0.8132803447468182 8 Q9UBM7,Q9UHX1 2 +Patellar aplasia 0.5957400330044407 0.7767004917519797 0.437335496673318 1.0 0.8132803447468182 4 Q9Y619,O75419 2 +Abnormal visual field test 0.5390894337220888 0.7766707019895253 0.4373530765201896 1.0 0.8132803447468182 6 P00846,P35222,P31749 3 +Meningioma 0.4604649210081823 0.7766678449972932 0.4373547625397673 1.0 0.8132803447468182 10 P02545,Q15437 2 +Cerebral hemorrhage 0.4375208279342906 0.7758032745485222 0.4378651502256949 1.0 0.8139037412395217 14 P05067 1 +Abnormality of the gingiva 0.3343615977887944 0.7753306677339512 0.4381442921562821 1.0 0.8140969714715087 49 P16278,P20700,O00754,Q14108,Q15056,Q96JJ3,Q15392,Q14739,P08236,Q9UBM7 10 +Ascites 0.386902533871801 0.7740995993218042 0.4388718944158438 1.0 0.8143368770865682 26 Q13043,O60566,Q14108,O15118,P61916,O75787,Q14739,P08236,P04062,Q01844 10 +Personality changes 0.4173502174276826 0.7738399300172145 0.4390254561962008 1.0 0.8143368770865682 16 P03886,P20700,Q14203,P49770,P00403 5 +Aplasia hypoplasia of the ovary 0.3954663608112497 0.7736300356582723 0.4391496049018593 1.0 0.8143368770865682 18 Q13049,O15078,P51809 3 +Focal segmental glomerulosclerosis 0.3904035404151856 0.7714440713516342 0.4404437610750091 1.0 0.8160853898387431 24 P03886,Q14108,O75431,O43707 4 +Wide nasal bridge 0.3006073387606156 0.768934448128327 0.4419322261296892 1.0 0.8172474673716671 167 Q13045,Q01105,O15344,P98175,P02545,Q8N201,Q5KU26,Q8N3R9,Q9Y366,Q9UBM7,O00192,Q96EK5,P11166,Q9UHX1,Q9Y487,Q9BUB7,Q6PGP7,Q969N2,Q5H8A4,P29372,O14936,P20700,P55011,O95155,Q15056,P52732,Q9Y448,O75530,O96028,O15228,Q15555,Q8WWY3,Q9NX62,P46783,Q01082,O60826,O75175,Q9UIG0 38 +Pain insensitivity 0.5656744777233395 0.7685811885314378 0.4421419763807328 1.0 0.8172474673716671 5 P39210 1 +Dermal translucency 0.4751189084348101 0.7678260842335596 0.4425905155926655 1.0 0.8174452025845419 9 P02545,O75844 2 +Large intestinal polyposis 0.4498739526865373 0.7666010216628145 0.4433187678558594 1.0 0.8178078033232531 12 P20585,Q15437 2 +Pituitary prolactin cell adenoma 0.6129120879120891 0.7660254263749048 0.4436611732683282 1.0 0.8178078033232531 3 O00170,P25490 2 +Short femur 0.5357832446134646 0.7632148660615754 0.4453352643662169 1.0 0.8199179768263908 6 Q9UHX1 1 +Punctate cataract 0.5915217499299452 0.7608223952876384 0.4467631560069085 1.0 0.8199823223915497 4 P08670 1 +Abnormal renal pelvis morphology 0.3278386586405646 0.7604406152159326 0.4469912535175315 1.0 0.8199823223915497 60 P20700,Q8NCH0,O95155,P98175,O60826,P23786,O43505,O75718,Q71SY5,Q9UBM7 10 +Thickened calvaria 0.4570415619333938 0.7598272400546137 0.447357858015291 1.0 0.8199823223915497 10 Q7RTS9 1 +Autoimmune thrombocytopenia 0.4570323013653043 0.7597817586760303 0.4473850483124884 1.0 0.8199823223915497 10 P00813 1 +Submucous cleft soft palate 0.6111755364621596 0.7596101287435296 0.4474876629190811 1.0 0.8199823223915497 3 Q15233 1 +Acute coronary syndrome 0.3907285006380401 0.7588353866198266 0.4479510344937205 1.0 0.8205078664928337 22 P35579,Q15056,Q9NZ08,P02545,O75844,P06280 6 +Thick corpus callosum 0.6104025764822405 0.7567584582437248 0.4491945849295433 1.0 0.8214178898793459 3 Q15233 1 +Hypoparathyroidism 0.4141489595121127 0.7550016488195705 0.4502479929071892 1.0 0.8214178898793459 16 P03886,Q969N2,O00192,P00403 4 +Spinal cord lesion 0.4723226134052319 0.7547501369078398 0.4503989174794518 1.0 0.8214178898793459 9 O00400,O75298,Q9Y2U8,P35222 4 +Abnormality of lower limb joint 0.3073811381534492 0.7544667350742621 0.4505690125462562 1.0 0.8214178898793459 185 Q86XL3,Q9HD42,Q7RTS9,Q8TD16,P02545,P06753,O75298,Q9Y366,Q9UBM7,O00192,Q9NR77,P16278,Q9UHX1,Q8WVQ1,Q8N0X7,Q96L58,Q9Y487,O75787,O75718,O95831,Q6ZXV5,Q969N2,O00754,P55011,P07602,Q15056,P23786,Q03252,Q9H9S5,P08236,O75431,P51798,O96028,Q9UQE7,Q9NX62,Q01082,Q96HY6,Q9NUQ7,O75844,Q9UIG0 40 +Dicarboxylic aciduria 0.3783733279863323 0.7538420893360375 0.4509440473650636 1.0 0.821640337424506 28 P49748,P23786,O43772,O14678,P48735,Q9NUN5 6 +Bloody diarrhea 0.4870530173561171 0.7496033362358792 0.4534936409019132 1.0 0.8244855044096991 8 P78536,Q6PGP7,Q02241 3 +Abnormality of the thyroid gland 0.3115754627825162 0.7474661609396411 0.4547822216672896 1.0 0.8247390253740803 119 Q13045,Q8N3U4,O76024,P02545,P42224,O00192,Q14683,O60313,O60566,Q13868,P42892,P55265,O14654,P00813,Q6PGP7,Q96RR1,Q96L73,P03886,P00403,Q13043,P20585,O95155,Q15046,Q15056,Q7LG56,O95470,P48735,O00443,P35222,P31749,P04066,P27635,Q13423,P54277,Q15437,Q9UIG0 36 +Infantile muscular hypotonia 0.3189006471427413 0.7470474291154858 0.4550349317623692 1.0 0.8247390253740803 75 P16278,P03886,O00754,P07602,P49748,Q9Y487,P00846,Q9H9S5,P10253,Q9GZY8,O14936 11 +Agenesis of corpus callosum 0.3207027679105074 0.7460370855750462 0.4556450127094988 1.0 0.8247390253740803 95 Q86XL3,O15344,Q71SY5,Q9HC21,O60566,Q9UHX1,P80404,Q15392,Q9NXR1,Q5H8A4,P29372,P03886,Q9Y3D3,P55011,O95155,P23786,O43505,P11177,Q9H9S5,O96028,Q9Y3C6,P35606,Q8NAT1 23 +Generalized myoclonic seizure 0.3398694841740979 0.7460265474496702 0.4556513784246401 1.0 0.8247390253740803 45 Q05639,P11166,P16278,Q01105,O60566,P03886,P07602,Q96N66,P00846,Q969N2,Q9Y4W6,Q9Y448,Q8NHS3,Q9NXR1,P04062,Q9Y619,Q96L73 17 +Extrapyramidal muscular rigidity 0.5012951938475958 0.7453737053003714 0.456045835240479 1.0 0.8247390253740803 7 Q9BPX6,Q9H6K4,O75787 3 +Decreased activity of mitochondrial complex i 0.3521941654468665 0.745209107056483 0.4561453182256278 1.0 0.8247390253740803 37 P03886,Q70HW3,Q9UBX3,O43676,O75380,Q96CU9 6 +Lymphopenia 0.3738636495172442 0.7438152598869799 0.4569882469179354 1.0 0.8256704445675139 29 Q13432,Q13043,P26038,P28070,P42224,Q9Y448,O95470,P00813,Q6PGP7 9 +Aplasia hypoplasia of the optic nerve 0.3819590010762266 0.7397217133953093 0.459468870062623 1.0 0.8285416527671747 26 Q9UHX1,Q8N3U4,Q9Y448,Q9H9S5,Q9NXR1,P07196,O14936 7 +Short digit 0.2965206364751517 0.7393970407716869 0.4596659386784862 1.0 0.8285754914813521 162 Q7RTS9,P02545,Q8N3R9,Q9Y366,Q9UBM7,P11166,Q9UHX1,Q8WVQ1,Q8N0X7,O95831,Q14739,Q13868,P00813,O14936,Q9Y3D3,P55011,O95155,Q03252,Q9Y448,P51798,O96028,P11274,Q9UQE7,Q9NX62,Q13555,P46783,Q15437,Q96RK4,O60826,O75844 30 +Focal impaired awareness seizure 0.3884812483077002 0.7385820071488686 0.4601608532891172 1.0 0.8287054885183968 21 Q05639,Q01105,Q96JM3,Q00610,P22466,Q96CW1,Q96N67,Q96L73,P19022,P67870 10 +Abnormality of the cervical spine 0.3095563746871796 0.7380340247307485 0.460493773375775 1.0 0.8287054885183968 121 Q7RTS9,Q8N201,O00192,Q9UBM7,Q96EK5,P16278,A2RRP1,P11166,Q9UHX1,Q8NCH0,Q8WVQ1,Q96L58,P15586,O95831,Q13049,O00754,O15078,Q9Y448,Q9H9S5,P08236,Q9UQE7,Q15555,P04066,Q96RK4,P46783,Q96HY6,O60826 27 +Aggressive behavior 0.3189219419852397 0.7376598613530749 0.4607211691799269 1.0 0.8287054885183968 78 Q05639,Q71SY5,Q9BRT2,P54802,O75503,Q9UBM7,P11166,O95714,Q10713,Q8WYQ5,Q6DKK2,Q96L73,Q15233,P52732,P17480,P35222,P55795,Q01082,Q93009,P23378 20 +Oral cavity bleeding 0.4994532154394292 0.7375169417112682 0.4608080444010194 1.0 0.8287054885183968 7 Q6UN15,Q14980,Q02241,P40763,Q9BZK7 5 +Delayed cranial suture closure 0.3729097371592627 0.73686394309977 0.4612050930314562 1.0 0.8290986720762773 29 Q9UQE7,Q8NCH0,O95155,Q9Y487,O75718,P02545,O75431,O75844 8 +Abnormality of the alveolar ridges 0.4975245239372041 0.7293071298378323 0.4658138119195096 1.0 0.833829141555585 7 Q15392,P98175 2 +Tented upper lip vermilion 0.3828431260331065 0.7290195053245045 0.4659897311426413 1.0 0.833829141555585 25 Q13045,Q4J6C6,Q71SY5,Q96F07,Q969N2 5 +Recurrent acute respiratory tract infection 0.6022562322730428 0.726854317634625 0.4673152043488766 1.0 0.8352012551596362 3 Q03518 1 +Hemiparesis 0.3877161935020229 0.7263715600942752 0.4676110210477886 1.0 0.8352012551596362 19 P03886,P11166,O60313,Q9NZ08,P00403 5 +Abnormal aortic valve physiology 0.3430019891493176 0.7262994938800389 0.4676551895686192 1.0 0.8352012551596362 42 P16278,O00754,O60566,Q9UHX1,Q15056,Q9NZ08,P02545,Q01082,Q6ZXV5,O60826,O75844,P11274,Q9UIG0 13 +Hepatitis 0.387067588714765 0.7252326324994285 0.4683093265384066 1.0 0.8352676763029563 20 P11717,Q9Y2V7,Q9NWH9,P42224,P08236,Q9Y619,P35222 7 +Myoclonic seizure 0.3243786557779528 0.7248167104717984 0.4685644827790454 1.0 0.8352676763029563 60 Q05639,Q01105,O75503,Q9Y619,P16278,P11166,O60566,Q8NHS3,Q9NXR1,Q969N2,Q96L73,P03886,P07602,P00846,Q9UBB6,Q9Y4W6,Q9Y448,Q9Y3C6,Q96N66 19 +Unsteady gait 0.326150824691289 0.7241875762487824 0.4689505847803772 1.0 0.8352676763029563 55 Q05639,P31040,Q9NR77,P11166,Q5THJ4,O95714,O75569,Q8N3U4,O75787,Q10713,O95831,Q96F07,Q9H6K4,O75503,P07196,P49770,Q14738 17 +Acetabular dysplasia 0.445677810989624 0.723024251640463 0.4696649848218626 1.0 0.8358993429594774 11 P16278,Q96L58 2 +Aphasia 0.3408485346360289 0.7220989395302737 0.4702336501568478 1.0 0.8362917882834733 43 P03886,P55011,P17480,O96008,Q8N3R9,O00192,P05067,P00403 8 +Ulnar deviation of finger 0.4808271276928735 0.7220103394308353 0.4702881207061558 1.0 0.8362917882834733 8 Q96L58,Q9UBM7 2 +Infectious encephalitis 0.4449718533144641 0.7195014838176539 0.4718319883073989 1.0 0.8371910078902187 11 Q9NZ08,Q14739 2 +Retinal dystrophy 0.3219996399117649 0.7183143862108298 0.4725634617618071 1.0 0.8377134474572109 63 P03886,Q15051,O15078,P00846,O43505,P52732,Q13868,Q6P4Q7,Q8NHS3,Q9H9S5 10 +Status epilepticus 0.3259685008892933 0.7181200709790917 0.4726832556178282 1.0 0.8377134474572109 52 P11166,P07602,Q9Y487,Q15392,P52732,Q03252,P42892,Q96RR1 8 +Holoprosencephaly 0.4078061554597771 0.7178536834756452 0.4728475086464954 1.0 0.8377134474572109 16 Q9UBM7,Q9H9S5,O60566,O15078 4 +Aplasia hypoplasia of the skin 0.3241045140342444 0.7171609733814722 0.4732747768091172 1.0 0.8381508718871828 59 Q8NCH0,Q96L58,Q15392,P02545,Q13126,O75431,O96028,O75844 8 +Severe postnatal growth retardation 0.439640252535556 0.714042155076081 0.4752011129614146 1.0 0.8396424227877164 12 O96028,Q9UQE7,P27635,O76024 4 +Short palm 0.3817049682914522 0.7127007143726568 0.4760309743422373 1.0 0.8400227757733639 24 P02545,Q13555,P11274,Q9UHX1 4 +Mandibular prognathia 0.3380113943139378 0.7126090558387282 0.4760877064451152 1.0 0.8400227757733639 44 P16278,Q13045,O00754,P55011,Q9UHX1,O95714,Q7RTS9,Q8N3U4,P52732,Q71SY5,O75175,Q96L73 12 +Basal ganglia calcification 0.4473038155008136 0.712241568855183 0.4763151999369925 1.0 0.8400227757733639 10 P03886,O60313 2 +Loss of ability to walk 0.3965697858128415 0.7122334774075281 0.4763202096326262 1.0 0.8400227757733639 17 Q96RR1,Q9H9S5,P00846 3 +Obstructive sleep apnea 0.4433718515908648 0.7115277302638813 0.4767572732053811 1.0 0.8401776368268753 11 P51114,Q969N2,Q15233 3 +Urethral stricture 0.5980449478747599 0.7115077970113146 0.4767696208978846 1.0 0.8401776368268753 3 O75419 1 +Sloping forehead 0.3243992623561462 0.7092822427186257 0.4781493456273993 1.0 0.8416515186100472 56 Q86XL3,O60566,P98175,O15078,P23786,P35606,Q8N3U4,P52732,Q9H9S5,Q9BSJ2,Q9NXR1,Q15021,O15287,Q9HC21,Q96EK5,Q16625,O14936 17 +Generalized hypopigmentation 0.4465327241296301 0.7084951739232178 0.4786378081227791 1.0 0.8418735406307928 10 O95714,Q6PGP7,Q9Y2U8,Q86YV9 4 +Peters anomaly 0.5769525305744267 0.7065348780570201 0.4798555707042435 1.0 0.8433770185562102 4 P19022,Q9H9S5 2 +Pulmonary hypoplasia 0.3715330727414624 0.7049236962846166 0.4808577226258503 1.0 0.8444995604846284 28 P98175,Q96L58,Q14739,P02545,P25705,Q9UBM7,O75844 7 +Limb dysmetria 0.5961503368232764 0.7046298294466131 0.4810406300664072 1.0 0.8445016274720794 3 Q7LG56 1 +Abnormality of the brainstem white matter 0.5761004821777116 0.703388507836193 0.4818136664117864 1.0 0.8455007479040554 4 P20700,O15078 2 +Abnormality of the phalanges of the toes 0.3839793098613984 0.7025479237821748 0.4823375258647839 1.0 0.8455007479040554 19 Q8WVQ1,P02545,Q71SY5,O75431,O75844 5 +Endocarditis 0.5204426855514847 0.7013886922716608 0.4830604768598259 1.0 0.845652264858182 6 Q9NZ08 1 +Dolichocephaly 0.3401016072085506 0.7011597937300645 0.4832032982342975 1.0 0.845652264858182 42 Q4J6C6,O95714,O96028,Q7RTS9,O15287,Q8N201,Q01082,P42356,Q9Y366,Q5H8A4,O75175,P31749 12 +Aplasia hypoplasia of the cerebral white matter 0.4408558095515739 0.6990186384967413 0.4845403828805925 1.0 0.8456896556205606 11 P03886,P11166 2 +Thoracic scoliosis 0.4366661856733421 0.6988766406617779 0.4846291269458904 1.0 0.8456896556205606 12 P02545,O75844,Q9UHX1 3 +Carious teeth 0.3239184817027049 0.6983643976423527 0.4849493354908778 1.0 0.8458543035450447 50 P16278,Q9Y366,Q15555,Q15056,O95714,Q9Y487,Q96L58,Q6P4Q7,P51798,O00192,P31749,Q9UIG0 12 +Patellar dislocation 0.381031952720727 0.694949354119441 0.4870870413669319 1.0 0.8475508293316526 22 Q15056,Q8WVQ1,Q9NX62,Q6ZXV5,O00192 5 +Hyperreflexia 0.3285938554424262 0.6890764542355203 0.4907751564067879 1.0 0.8513150033686848 259 Q99720,Q86XL3,Q9HD42,Q7RTS9,Q8TD16,Q5KU26,O75298,O75027,O14773,O75503,Q9Y619,Q7KZN9,Q16625,Q9NR77,Q5THJ4,O60313,O00400,P11166,Q8N0X7,Q9BQT8,O75787,P80404,O95831,O75251,Q14203,Q14739,Q9H6K4,Q9NXR1,Q969N2,Q13813,Q6DKK2,P50336,P03886,P20674,P20700,O14936,O00754,P07602,Q15233,Q15056,P55011,P00846,Q9Y4W6,Q96F07,Q9H9S5,O15287,Q9BX67,Q96CU9,Q9Y3C6,Q96N66,Q15555,Q8WWY3,O75569,Q9NZ08,Q9NQT5,P35606,O75306,Q01082,Q9BSJ2,O43681,P42356,P23378,Q9GZY8,Q9UIG0 64 +Pectus carinatum 0.3453582928415196 0.689062521483201 0.4907839238271372 1.0 0.8513150033686848 37 P16278,O00754,P55795,P55011,Q96L58,Q7RTS9,Q71SY5,P08236,P17480 9 +Absence of subcutaneous fat 0.5171006335483085 0.6880651131319295 0.4914117785623921 1.0 0.8513474180118783 6 O75844 1 +Elevated circulating follicle stimulating hormone level 0.5910294911534855 0.6861244286206402 0.4926346475218293 1.0 0.8513474180118783 3 P51809 1 +Abnormality of the plantar skin of foot 0.3348361258592251 0.6845003691256901 0.4936592563645887 1.0 0.8524840447143233 44 Q9Y487,P16615,Q15437,O75431,P09493 5 +Mania 0.3810104691090988 0.6836971562743104 0.4941664195535518 1.0 0.8529587060738328 19 P03886,P16615,Q7LG56,O00192,Q96RR1 5 +Abnormal ovarian physiology 0.3684577263815707 0.6830650956937332 0.4945657099655296 1.0 0.8529587060738328 28 P02545,Q15051,O75844,O15078 4 +Abnormal tongue physiology 0.3808951811358099 0.6829665653867838 0.4946279698631344 1.0 0.8529587060738328 19 P51114,Q9BQT8,O95831,P10253,Q9NWS8 5 +Osteopetrosis 0.5897120733004391 0.6813841799355476 0.4956284304289371 1.0 0.8530315985938041 3 Q15392 1 +Metrorrhagia 0.4853757446942295 0.6780191668461287 0.4977595406278443 1.0 0.8545796395278957 7 Q6UN15,P40818,Q14980,P40763,Q9BZK7 5 +Abnormality of fibula morphology 0.4280472043478751 0.6779314348900269 0.4978151676785052 1.0 0.8545796395278957 13 Q9NWH9,O75431,Q96HY6 3 +Skin nodule 0.3774894721641362 0.6775161861592366 0.4980785038813962 1.0 0.8546866699571123 23 Q9NZ08,P16615,Q15437,P52732,P06280 5 +Mild postnatal growth retardation 0.5287009063444024 0.6772531347459544 0.4982453602138621 1.0 0.8546866699571123 2 P10644 1 +Abnormal paranasal sinus morphology 0.3702028321331478 0.6760331389408727 0.4990196052020224 1.0 0.8552941234494585 27 P00813,P28070,O00754,P04066 4 +Low frustration tolerance 0.4703142023524866 0.6758722034590013 0.4991217872688347 1.0 0.8552941234494585 8 P04062,Q9UHX1 2 +Decreased plasma carnitine 0.4318482007612397 0.6744239597385214 0.5000418142599543 1.0 0.8558726743521208 12 O43772 1 +Aplasia hypoplasia affecting the fundus 0.3670354057360671 0.6729866927447218 0.5009557569209169 1.0 0.856503573902547 28 Q9UHX1,Q8N3U4,Q86YV9,Q9Y448,Q9H9S5,Q9NXR1,P07196,O14936 8 +Lipoma 0.4838174870035817 0.6714976619983607 0.5019035483870962 1.0 0.8571649354483042 7 P31749,P27635,Q15437 3 +Sleep disturbance 0.2898414128146747 0.669400624383775 0.5032399534350551 1.0 0.8585007575670709 157 Q05639,Q13045,Q01105,O75175,P51114,Q8N3U4,Q71SY5,P06753,Q8N3R9,P54802,O75503,Q9UBM7,P11166,Q9UHX1,Q8N0X7,O95714,P15586,Q14203,O95831,Q8NHS3,Q96RR1,Q969N2,Q96KP1,O14936,P55011,Q15056,Q15233,P50897,P52732,Q9UBB6,Q9H9S5,P04062,P31749,P35222,Q96N66,Q14139,Q9UQE7,Q01082,Q93009,Q9NUQ7,P07196,Q9UIG0 42 +Fatigue 0.3143014443069556 0.6679701351638647 0.5041526562358665 1.0 0.8591116221225051 86 Q70HW3,P07602,Q68CQ7,Q4J6C6,Q13423,Q9NZ08,Q9NWH9,Q15165,Q14203,Q14739,Q01082,P06753,Q96RR1,Q969N2,P11274,P06280 16 +Abnormal circulating cholesterol concentration 0.3532278895240722 0.6673454858585006 0.5045514783719249 1.0 0.8594760703791551 32 P07602,P61916,Q15392,Q14739,P02545,O75431,Q9UBM7 7 +Neoplasm of the rectum 0.378349405357379 0.6654895714581549 0.5057374115054052 1.0 0.8605498906135547 18 P31040,P20585,P54277,Q15437,P31749 5 +Abnormal umbilicus morphology 0.3118123966698149 0.6610033196402224 0.50861018466972 1.0 0.8635409310048188 69 O00754,Q15555,Q8NCH0,Q15056,Q9BUB7,Q9Y487,Q96JJ3,Q14739,P02545,Q9Y448,P08236,O75530,O00192,O75844,O14936 15 +Reduced tendon reflexes 0.3014671119986584 0.6599267343243955 0.5093008470861213 1.0 0.864397748871149 185 Q13045,Q99720,P51114,Q8TD16,Q71SY5,P02545,P06753,P10253,P39210,P54802,Q9HC21,Q9NR77,O60313,Q7Z406,Q9BQT8,O75787,O95831,Q9H6K4,Q96RR1,Q5H8A4,Q13049,P50336,P03886,P07602,Q15046,P00846,O43505,Q7LG56,Q96F07,P11177,Q9H9S5,P41440,Q9NWS8,Q8NAT1,Q5TAQ9,O43681,O00764,P23378,P07196 39 +Genital neoplasm 0.3283302602083004 0.6594251783902869 0.509622778200622 1.0 0.8646283498715919 46 P20585,O60566,Q13423,P51809,Q92878,P35222,Q15437,Q01844,P02545,P48735,Q9Y6D9,P31749,Q96L73 13 +Increased circulating lactate dehydrogenase concentration 0.4159390137768642 0.6587280081715797 0.5100704441274337 1.0 0.8650720269562718 14 P23786,P41440 2 +Infection related seizure 0.3757604259238576 0.6561066810802088 0.5117554860026226 1.0 0.867185468091994 21 P20700,P11166,Q96N66,Q01082,P05067 5 +Abnormal echocardiogram 0.5087863860958708 0.6551712086492987 0.5123575291336313 1.0 0.867185468091994 6 Q96RR1,P49748 2 +Abnormal larynx physiology 0.4061337867231551 0.6537616510401114 0.5132653768287916 1.0 0.867185468091994 15 Q68CQ7,P35637,Q15165,Q14203,Q92804,Q9H0U9 6 +Decreased circulating antibody level 0.3214726467565182 0.6535049759452771 0.5134307825635731 1.0 0.867185468091994 49 O00754,P26038,P02786,O75787,P14174,Q9Y448,P00813,Q969N2 8 +Generalized onset motor seizure 0.3181052585941694 0.6525612530734832 0.5140391719144728 1.0 0.8673711081650526 58 Q05639,Q01105,Q96N67,Q9Y619,P16278,P11166,O60566,Q8NHS3,Q9NXR1,Q969N2,O14936,P03886,Q96L73,P07602,Q15046,P00846,Q9Y4W6,Q9Y448,Q96N66 19 +Facial diplegia 0.4228715092802604 0.6511183732601737 0.5149700769712986 1.0 0.868311301772723 13 Q96RR1,P06753,Q9H9S5,Q7LG56 4 +Cerebellar malformation 0.3096809282541954 0.6506517044345134 0.5152713457529425 1.0 0.8685041507848835 73 O00754,O60566,Q15056,Q15233,O15078,P23786,Q9Y487,O60826,O43505,O75419,Q8NAT1,P15291,Q9H9S5,Q9UBM7,Q9UIG0 15 +Protruding ear 0.3232884736766527 0.650282418125539 0.5155098118604715 1.0 0.8685910426815123 48 P20700,Q8NCH0,Q15056,Q13555,O43505,P52732,Q8NAT1,Q01082,Q9Y448,Q9H9S5,Q9BSJ2,Q9UIG0 12 +Diaphragmatic weakness 0.5338799879565096 0.6466961691977043 0.517828602895311 1.0 0.8710633270631294 5 Q9NR77 1 +Variable expressivity 0.3125094196691867 0.6458958055186124 0.5183468362349264 1.0 0.8710633270631294 87 Q8TD16,P02545,P06753,Q9NR77,Q5THJ4,P11166,Q70HW3,Q8WVQ1,Q13868,Q9H061,Q13813,P00403,P03886,P07602,P52732,O43707,Q9Y4W6,Q6P4A7,Q9H9S5,Q9NWS8,Q9NQT5,P07196,Q9UEY8 23 +Renal cyst 0.309976240933369 0.6458771522841785 0.5183589173504712 1.0 0.8710633270631294 75 O00192,Q9UBM7,O60566,Q9UHX1,Q6PGP7,Q969N2,Q13049,P20585,O95155,Q15056,O15078,P23786,O43505,Q9BX67,Q9NWS8,Q9UQE7,Q96RK4,Q9NQH7,Q9UIG0 19 +Abnormality of the palm 0.3012998104964604 0.6427452032785428 0.5203894445381012 1.0 0.8722290290892138 123 Q15555,Q9UHX1,Q8NCH0,P98175,Q9Y487,Q13555,Q7RTS9,P16615,Q8WVM7,Q15437,O95831,Q71SY5,P02545,Q01082,O75431,P09493,O96028,P11274 18 +Increased arm span 0.5785052262600039 0.6414206255974606 0.5212494358839574 1.0 0.8722290290892138 3 Q96L73 1 +Abnormal arm span 0.5785052262600039 0.6414206255974606 0.5212494358839574 1.0 0.8722290290892138 3 Q96L73 1 +Hepatomegaly 0.3039013719436219 0.6409945800447832 0.5215262043571038 1.0 0.8722290290892138 194 Q14108,O15118,Q9HC07,O43772,P14174,P02545,P10253,P39210,P54802,P16278,P11166,P49748,P28070,O43676,O75787,P15586,O75251,Q14739,P00813,Q9BUB7,P03886,O00754,P07602,P23786,P00846,P08236,O75431,P51798,Q9BX67,Q96CU9,Q9NWS8,P04066,P61916,Q9NWH9,P31751,Q96HY6,O75380 37 +Abnormal circulating pyruvate family amino acid concentration 0.3697908699724882 0.6407654470992895 0.5216750853726093 1.0 0.8722290290892138 25 P03886,P20674,P22695,Q15046,P00846,Q7LG56,P25705,Q9BUB7 8 +Limited wrist movement 0.5050249796334665 0.640415258118813 0.5219026657759884 1.0 0.8722290290892138 6 P02545,O75844 2 +Limitation of neck motion 0.558356888812758 0.6386712798448964 0.5230368000931995 1.0 0.8725886518391721 4 P02545 1 +Flared metaphysis 0.4309810058077861 0.6337191711950042 0.5262641112533184 1.0 0.8755432532475173 10 Q96L58,Q96HY6,O75530 3 +Fluctuations in consciousness 0.4275265756085934 0.6334189378300794 0.5264601012904611 1.0 0.8755432532475173 11 P03886,P04062,O75306,P00403 4 +Hyperconvex nail 0.4599465319810321 0.6310056142172902 0.5280368535673052 1.0 0.8766656872194597 8 P42892 1 +Severe failure to thrive 0.5750412269969722 0.6292051917613567 0.5292147303624344 1.0 0.8778295256417558 3 O75844 1 +Abnormality of dental color 0.5556588682768525 0.6289751448684398 0.5293653284469819 1.0 0.8778295256417558 4 P16278 1 +Olivopontocerebellar hypoplasia 0.5550791294979441 0.6268970105530771 0.5307267469960739 1.0 0.8786203039867316 4 Q9H9S5,Q9Y5P6 2 +Lipoatrophy 0.3704992508722593 0.6264475198095083 0.5310214490440979 1.0 0.8787951117193458 22 P09493,P04066,O75431,Q03252 4 +Impaired antigen specific response 0.4220104822045222 0.6249834463055942 0.531981922706382 1.0 0.8797580052727962 12 P00813 1 +Dermal atrophy 0.3571553866054547 0.623311287506932 0.5330799817263134 1.0 0.8806337273665761 29 P02545,Q96L58,O75844,Q15392 4 +Constitutional symptom 0.323374797556521 0.6221286482341766 0.5338572786543585 1.0 0.8816043972660995 255 Q99720,Q14108,Q4J6C6,P14174,P02545,P06753,O75298,O00192,P06280,Q9NR77,P11166,Q70HW3,P49748,P28070,Q14203,Q14739,P42892,Q96RR1,Q969N2,Q13049,P50336,O14936,P20700,O00754,P07602,Q15056,P23786,P00846,Q7LG56,P52732,Q03252,O43707,Q9H9S5,Q8N1F7,P48735,P11274,Q68CQ7,Q13423,O75569,Q9NZ08,Q9NWH9,Q15165,Q01082,Q14566,O43681,Q96HY6,O75844,P07196 48 +Mesomelia 0.4997061500368682 0.6196919140316232 0.5354606402266349 1.0 0.8832541282821759 6 Q9UBM7 1 +Gowers sign 0.3999174734171504 0.6194551557049867 0.5356165555195118 1.0 0.8832541282821759 15 P06753,Q13049,Q8TD16,P07196 4 +Absence of secondary sex characteristics 0.526093056469311 0.6176308821388276 0.5368186827631798 1.0 0.8843113525851586 5 P51809 1 +Prolonged bleeding time 0.4707637085781366 0.6174351436896124 0.5369477475447 1.0 0.8843113525851586 7 P35579 1 +Blue nevus 0.513595166163134 0.6169393730233372 0.5372747154569792 1.0 0.8843113525851586 2 P10644 1 +Abnormal blood sodium concentration 0.4271669519512572 0.615632771207862 0.5381369172602335 1.0 0.8843113525851586 10 P50336 1 +Pseudobulbar signs 0.4200518674434854 0.6152257031074025 0.5384056755876059 1.0 0.8843113525851586 12 P20700,Q14203,Q15233 3 +Excessive salivation 0.3497498220328073 0.6150681823247982 0.5385096935051885 1.0 0.8843113525851586 31 Q9NR77,P55795,Q15233,Q8N0X7,P15586,O75787,Q03252,Q01082 8 +Hypoplastic heart 0.5512153451740199 0.6130961197378205 0.539812785757809 1.0 0.8854606478702924 4 O60826,Q8N3U4 2 +Chronic fatigue 0.4412855707174464 0.6124807981279783 0.540219698538229 1.0 0.8858154337004764 9 P07602 1 +Atrial arrhythmia 0.4224075686609831 0.6085597901562987 0.5428162637185483 1.0 0.8881926681338359 11 P02545,Q96RR1 2 +Ureteropelvic junction obstruction 0.5231439952867958 0.6067168275650939 0.544038852767752 1.0 0.8895666955706345 5 Q9UBM7 1 +Pediatric onset 0.3206687835661315 0.6063152766798654 0.5443054161495 1.0 0.8896895071567803 249 P22830,P55263,O15118,Q96N67,P02545,P06753,O75027,P54802,P39210,O14773,P06280,Q9NR77,P16278,P35579,P11166,Q70HW3,P22466,P49748,Q8N0X7,O75787,O95831,Q6ZXV5,Q8NHS3,Q969N2,Q13813,P20700,P07602,P23786,Q03252,O75431,P51798,P41440,Q96CU9,Q969M3,O00584,O75306,Q14331,Q14566,Q9BSJ2,Q9NUQ7,Q9NUN5,P07196,Q9GZY8 43 +Joint laxity 0.3088939802780744 0.6048306978802789 0.545291494330072 1.0 0.8903268613392911 86 Q9HC07,Q8WVM7,O75419,Q9Y619,P16278,Q9UHX1,Q8NCH0,Q8WVQ1,Q96L58,Q9Y487,Q5H8A4,Q96L73,O00754,Q15056,Q15233,O75530,P55795,Q01082,Q96HY6,Q9UIG0 20 +Hyperglycemia 0.4676084772621041 0.6045316707347986 0.5454902196033258 1.0 0.8903268613392911 7 O75844 1 +Abnormal mitochondrial morphology 0.4247622536367549 0.6042863145709693 0.5456533034418551 1.0 0.8903268613392911 10 Q9GZY8 1 +Parietal bossing 0.5097500686624463 0.6018619839548224 0.5472660114013206 1.0 0.8923316333269953 2 O14802 1 +Abnormality of dental structure 0.307822163623617 0.5998588917770523 0.5486002809440675 1.0 0.8932221558810586 82 P16278,Q15555,P55011,O00192,Q15056,Q96L58,Q9Y487,Q96JJ3,Q9HC07,P02545,Q6P4Q7,O75431,P51798,Q9Y366,Q9UBM7,O75844,Q9UIG0 17 +Mildly elevated creatine kinase 0.3646374272718208 0.5993458973278836 0.5489422472287264 1.0 0.8932221558810586 24 Q7Z406,P02545,Q9H9S5,P39210,Q9BPX6,Q96RR1 6 +Abnormal circulating metabolite concentration 0.3428951099068522 0.5975054496277428 0.5501699696596702 1.0 0.8936175634423235 379 P22830,Q86VD7,P55263,Q4J6C6,Q9HC07,O43772,P14174,P02545,P06753,P10253,P39210,O00192,P00390,Q9UBM7,P05067,P06280,Q00796,P11166,Q70HW3,Q9Y6N5,P49748,Q9Y487,P28070,O43676,P53985,Q15392,Q7Z406,O95831,O14678,O75251,Q14739,Q6ZXV5,Q9BPX6,Q96RR1,Q969N2,P32929,Q13049,Q9BUB7,P50336,O14936,P03886,P22695,P07602,Q15056,P23786,P00846,O43505,Q7LG56,Q9BWD1,Q03252,O43707,P11177,Q9H9S5,O75431,P51798,P09493,Q8N1F7,P41440,P48735,Q96CU9,Q13423,P61916,Q9NWH9,O75306,Q14331,P25705,Q01082,P15291,P31751,Q8NFF5,Q8NAT1,O75380,O75844,Q9NUN5,P07196,Q9UIG0 76 +Myopathy 0.3045411117290333 0.592008184917284 0.5538451075050823 1.0 0.8970784993294241 110 P51114,P02545,P06753,Q13126,O60313,Q8NCH0,O43676,Q7Z406,Q96RR1,Q13049,P03886,O00754,O95155,Q15056,P23786,P00846,Q7LG56,Q03252,Q9H9S5,P09493,Q9NWS8,O75306,P15291,Q8NFF5,P07196,Q9UIG0 26 +Abnormal shape of the frontal region 0.3036684165172838 0.591415942448343 0.5542417610360368 1.0 0.8974081754475481 112 Q13045,P55263,O15344,Q4J6C6,Q8N201,Q9Y366,P16278,O60566,Q96L58,Q9Y487,Q15392,P15586,Q14739,Q6PGP7,Q5H8A4,P29372,P20674,O00754,O95155,Q15233,Q9Y448,O75431,P51798,O96028,Q9UQE7,P04066,O60826 27 +Abnormal labia morphology 0.3661209484164189 0.5903491481737682 0.5549565954669298 1.0 0.8979398673867767 19 Q9UQE7,P51809,O95714,O75419,P02545,Q8IY37,Q9Y619,Q15042 8 +Abnormal uvea morphology 0.3030169664734624 0.5887272678932296 0.5560442429263626 1.0 0.8987609032621937 113 P14174,Q9UBM7,Q9Y619,Q96EK5,Q9NR77,Q9UHX1,O95714,Q9NXR1,Q5H8A4,O14936,O95155,Q15056,O15078,Q8WXW3,O43505,P52732,Q9H9S5,O15484,P04439,O15287,O96028,P31749,Q86YV9,Q8NAT1,Q01082,O60826,Q9UIG0 27 +Morphological abnormality of the vestibule of the inner ear 0.5053556715188043 0.5847781618522836 0.5586968901179394 1.0 0.9015024564267016 2 Q06124 1 +Aplasia hypoplasia of the tongue 0.4626533310072274 0.5844072436013573 0.5589463544681266 1.0 0.9015024564267016 7 O15078,Q03252 2 +Secundum atrial septal defect 0.5620879120879134 0.5841510601452954 0.5591186844942642 1.0 0.9015024564267016 3 P34897,Q15650 2 +Mixed hearing impairment 0.4343534537852202 0.5815786878267557 0.5608505017411551 1.0 0.9015024564267016 9 Q96L58,O00754 2 +Unusual infection 0.3114985377899513 0.5809804189423832 0.5612536506401824 1.0 0.9015024564267016 225 P26038,Q7RTS9,P14174,Q71SY5,P06753,P10253,P54802,Q9UBM7,Q13432,P16278,P11166,Q9Y487,P28070,P02786,O75787,P15586,Q14739,Q9NXR1,P00813,Q6PGP7,Q9BUB7,P20700,O00754,P07602,Q15056,Q03252,Q9Y448,P08236,P51798,O96028,P78536,P11274,P04066,Q13423,Q9NZ08,Q86YV9,Q01082,O60826,Q9NUN5,Q9UIG0 40 +Infantile spasms 0.3416642771339556 0.5803572285178983 0.5616737421737366 1.0 0.9015024564267016 32 P03886,Q9UBX3,P00846,Q96N67,Q01082,Q13813,O14936 7 +Abnormal proportion of cd4 positive t cells 0.4196394364038859 0.5802687515770132 0.561733396640405 1.0 0.9015024564267016 10 Q9Y448,O75787 2 +Increased urinary non proteinogenic amino acid level 0.4615991599598651 0.5801487467541936 0.5618143132799069 1.0 0.9015024564267016 7 Q9NUN5 1 +Abnormal temper tantrums 0.447484809974313 0.5780392125950142 0.5632376454921766 1.0 0.9034196552637372 8 Q06787,Q93009,P04062,P35222,Q14738 5 +Abnormality of corneal stroma 0.3640713558747802 0.5771901512661437 0.5638110094458295 1.0 0.9034585382395758 18 P16278,P10619,O43505 3 +Misalignment of incisors 0.4882572732167085 0.5756944094610702 0.564821754774905 1.0 0.9045837513990552 6 Q8WVM7,Q96N67 2 +Underdeveloped supraorbital ridges 0.4077046443722887 0.5737264141118003 0.5661529509875662 1.0 0.9054423843928942 13 P52732,Q9Y448,P98175 3 +Abnormal nervous system electrophysiology 0.3027518889701814 0.5734495813709135 0.5663403275977825 1.0 0.9054423843928942 202 Q99720,Q14108,Q96N67,Q71SY5,P02545,P39210,O14773,O75503,Q00796,Q9NR77,P11166,Q9UBX3,Q7Z406,O95831,Q8NHS3,Q969N2,Q13813,O14936,P03886,P20700,P55011,O95155,P07602,P50897,Q96F07,Q9H9S5,O96028,Q96N66,Q01082,O43681,Q9NWW5,P07196,Q9GZY8 33 +Abnormal chorioretinal morphology 0.3332143600788383 0.5717997566177823 0.5674576422086277 1.0 0.9058796644873626 34 O15078,O43505,P52732,Q10713,Q8NAT1,Q01082,Q9H9S5,Q9NXR1,P04439,O60826,Q9Y619,P31749,O14936 13 +Abnormal choroid morphology 0.3332143600788383 0.5717997566177823 0.5674576422086277 1.0 0.9058796644873626 34 O15078,O43505,P52732,Q10713,Q8NAT1,Q01082,Q9H9S5,Q9NXR1,P04439,O60826,Q9Y619,P31749,O14936 13 +Thick eyebrow 0.3146982715921185 0.571603635298908 0.5675905320697505 1.0 0.9058796644873626 48 O00754,Q9UQE7,Q9UHX1,P04066,P98175,P15586,Q96N67,O95831,Q01082,P08236,Q9BSJ2,Q96EK5 12 +Bilateral coxa valga 0.5583954416514744 0.5714993554717952 0.5676611971136647 1.0 0.9058796644873626 3 O00754 1 +Angina pectoris 0.5388481056789192 0.5695289751254272 0.5689972129454395 1.0 0.9061446362431314 4 O75844,P06280 2 +Bird like facies 0.4857521639287053 0.5661861995138678 0.5712672103666658 1.0 0.9088253086524808 6 P02545,O75844 2 +Abnormal enzyme coenzyme activity 0.3033845725088777 0.5654984561686733 0.5717347740626435 1.0 0.9090873158337908 205 P55263,O15118,Q9HC07,O43772,P10253,P39210,P16278,P35579,P49748,P28070,Q96JJ3,O75787,Q14739,O14678,P00813,Q96RR1,Q969N2,P10619,P50336,P03886,P22695,Q9Y3D3,O00754,P07602,P23786,P00846,O43505,Q7LG56,Q9H9S5,O75431,P51798,P41440,P11274,P61916,P46783,Q15437,Q01082,Q9NUN5,Q14566 39 +Abnormality of the parathyroid gland 0.3583441526587047 0.5648237703517475 0.572193637304933 1.0 0.9093651958125936 25 P03886,P48735,O00192,Q969N2,P00403 5 +Hoarse voice 0.3456680322444032 0.5625328463375967 0.5737530310430587 1.0 0.9102556748077408 30 Q13045,Q15056,Q8N0X7,Q7Z406,Q9UIG0,Q9Y2U8,O95140,Q01082,P06753,O75530,Q96HY6,Q96L73 12 +Anal stenosis 0.5366657607120164 0.5619425329522293 0.5741551735759143 1.0 0.9102556748077408 4 O60934,O75419 2 +Abnormality of the female genitalia 0.2768527091853739 0.5615368538903276 0.5744316139797743 1.0 0.9102556748077408 144 Q92878,Q9UIG0,O75419,P02545,O00192,Q9UBM7,Q9Y619,O60566,O95714,Q15392,Q96RR1,Q13049,P20585,O95155,Q15056,O15078,Q03252,O15287,O96028,P48735,P31749,Q15051,Q9UQE7,P51809,Q15437,P31751,Q16740,Q96RK4,O75844,P49770,Q01844 31 +Nonketotic hypoglycemia 0.4844921399885555 0.5614207218753073 0.5745107609919615 1.0 0.9102556748077408 6 P23786,P31751 2 +Cerebral palsy 0.4046001724576588 0.5581302207832664 0.5767554655425182 1.0 0.9125579327123194 13 P48735,P98175 2 +Bruising susceptibility 0.3312698062653691 0.5568064586754667 0.5776596705976753 1.0 0.912809742411956 34 P35579,Q14108,Q8NCH0,Q96L58,Q13126,P51798 6 +Abnormal b cell morphology 0.4043104017830503 0.5566791248026364 0.577746682066508 1.0 0.912809742411956 13 P00813,Q9Y448 2 +Spinal cord compression 0.5350827485200204 0.5564595139262438 0.5778967639715891 1.0 0.912809742411956 4 Q96L58 1 +Malignant neoplasm of the central nervous system 0.3548750602970288 0.5553795820112002 0.5786350553869168 1.0 0.913414924381708 26 P20585,Q15555,O95155,P48735,P35222,Q96L73 6 +Ulnar deviation of the hand or of fingers of the hand 0.4040396624474963 0.5553240627591666 0.5786730228921344 1.0 0.913414924381708 13 Q96L58,Q9UBM7,P11274 3 +Abnormality of ocular smooth pursuit 0.3596430021393386 0.5538354287898276 0.5796914792807568 1.0 0.9145880585668628 21 O00754,P41440,O14773 3 +Limitation of joint mobility 0.3019180013359259 0.5536624760802842 0.5798098602405806 1.0 0.9145880585668628 109 Q13045,Q7RTS9,Q8TD16,Q8WVM7,P02545,P06753,P54802,Q9HC21,P16278,Q96L58,P15586,Q9H6K4,O00754,O95155,Q15056,P23786,P08236,O75431,O75530,P48735,Q9UQE7,O75844,Q9UIG0 23 +Skin ulcer 0.3302759833143407 0.5491686550490256 0.5828897131767032 1.0 0.9168690873857388 34 Q8IZA0,P52732,P02545,P39210,P48735 5 +Tube feeding 0.3013139980171049 0.5490876472374462 0.582945302067376 1.0 0.9168690873857388 75 Q05639,Q99720,Q01105,P35637,Q8N3U4,Q71SY5,P06753,Q9UHX1,Q969N2,P55011,P07602,Q15233,Q9UBB6,Q9Y448,P17480,Q96N66,Q14139,Q6PJT7,Q9NUQ7,Q9GZY8 20 +Hirsutism 0.3044268015460258 0.5483306065646566 0.5834649153037348 1.0 0.9171027739507704 65 P16278,Q9UQE7,Q15555,O95155,O15078,Q96JJ3,P15586,Q03252,P02545,P08236,P54802,Q13049 12 +Iris hypopigmentation 0.4808561196419573 0.5477343969726131 0.5838742900944844 1.0 0.9171027739507704 6 O95155,Q86YV9 2 +Reticular hyperpigmentation 0.4949189783026544 0.5448725470662776 0.5858411786924607 1.0 0.9187998506189216 2 Q9H488 1 +Cavum septum pellucidum 0.401711649047813 0.543701758636567 0.5866467220493059 1.0 0.9191326086861512 13 O96028 1 +Decreased circulating iga level 0.4085664696711129 0.5424306969349727 0.5875218376141373 1.0 0.9195375415318452 11 P00813,Q969N2 2 +Abnormality of the breast 0.2984616059906868 0.5413904009999982 0.5882385220300108 1.0 0.9195375415318452 115 Q92878,Q8IWS0,O75419,P02545,P28340,Q9UBM7,Q9Y619,Q96EK5,Q14683,O75330,P57740,O14678,Q9BZK7,Q969N2,Q5H8A4,Q96KP1,Q12768,Q15067,Q15233,P23786,Q9Y448,O75530,O96028,P19022,P48735,P35222,P31749,Q06787,P11802,Q9UQE7,Q15555,P51809,Q96A33,Q15437,Q01082,P31751,Q8IY37,P10586,O60826,Q14738 40 +Congenital malformation of the left heart 0.5051408577470897 0.5413152387921688 0.5882903186946795 1.0 0.9195375415318452 5 O60826,Q8N3U4 2 +Contractures involving the joints of the feet 0.3575684732345566 0.5408928859807229 0.5885814146190187 1.0 0.9196831989692602 21 O60313,Q8N2K0,P50402,Q8WXH0,Q8IWS0,Q8IZA0,Q8TD16,P02545,Q9H9S5,Q14738 10 +Dyslexia 0.4249471357780751 0.5402728170180653 0.5890089018540245 1.0 0.920016762124668 9 P11166,Q9H6K4,Q01082 3 +Long philtrum 0.2816921294447376 0.5400089635067443 0.5891908508893935 1.0 0.920016762124668 138 Q8N201,P06753,Q8N3R9,O00192,Q9UBM7,Q16625,P16278,A2RRP1,P11166,O60566,Q9UHX1,Q8NCH0,Q8WVQ1,Q96L58,Q9Y487,O75718,Q13868,Q9BUB7,Q6PGP7,Q969N2,O14936,P20700,P55011,O95155,Q15056,P52732,O75431,O75530,Q9UQE7,Q15555,Q13555,Q9UIG0 32 +Eversion of lateral third of lower eyelids 0.4932710793737887 0.5386620519829745 0.5901200626793808 1.0 0.9208488687948564 2 P60953 1 +Acne 0.3761089346885285 0.5369135873220247 0.5913273050831593 1.0 0.9211212017745286 16 Q92542,Q9NZ08 2 +Abnormality of the mitochondrion 0.3024424306063024 0.5359076494325848 0.5920223775091573 1.0 0.9211212017745286 102 Q4J6C6,O43772,Q7KZN9,Q70HW3,Q9UBX3,P49748,O43676,Q7Z406,O75251,Q9BUB7,Q96RR1,P00403,P03886,P20674,Q15046,P23786,P00846,Q7LG56,P11177,Q9Y2R0,Q96CU9,O75306,O75380,Q9GZY8 24 +Unconjugated hyperbilirubinemia 0.5477215773311258 0.5354427128181511 0.5923437612213531 1.0 0.9211212017745286 3 O14936 1 +Juvenile aseptic necrosis 0.5034100750886715 0.5351468532749819 0.5925483134250609 1.0 0.9211212017745286 5 Q9NUQ7,Q8IWS0 2 +Abnormal cortical gyration 0.2761388707887102 0.5351464429262613 0.5925485971556097 1.0 0.9211212017745286 146 Q86XL3,Q01105,P07942,Q8TD16,Q71SY5,Q5KU26,Q9HC21,Q96EK5,Q16625,Q9Y487,Q15392,Q6ZXV5,O14936,P20700,P55011,P23786,Q8WXW3,O43505,P52732,Q03252,P11177,Q9H9S5,Q9Y3C6,Q9NWS8,Q96N66,P35606,Q8NAT1,Q9BSJ2,Q9NUQ7 29 +Allergy 0.4370775319191052 0.5347254009779995 0.5928397542282524 1.0 0.9211212017745286 8 P00813 1 +Gonadoblastoma 0.5470791161345923 0.5332979315591524 0.5938273592825691 1.0 0.9211212017745286 3 P51809 1 +Delusions 0.3567425423740489 0.5327774889994962 0.5941876184078114 1.0 0.9211212017745286 19 O00754,P07602,P49770,O43681,Q8WYQ5,P50336 6 +Swan neck like deformities of the fingers 0.4916231804449229 0.5324772213516386 0.5943955141950732 1.0 0.9211212017745286 2 Q9UBC1 1 +Ambiguous genitalia 0.3491784607985109 0.5320933827404825 0.5946613202702902 1.0 0.9211212017745286 27 O60566,Q8TAA9,Q14839,O15078,P51809,Q15392,Q8IY37,Q9UBM7,Q9H0U9 9 +Poor motor coordination 0.3917686089182218 0.5317636453749987 0.5948897048925708 1.0 0.9211212017745286 14 O75503 1 +Abnormal aortic valve morphology 0.3156384687927629 0.5315064537341949 0.5950678702731809 1.0 0.9211212017745286 45 Q9UQE7,Q9UHX1,Q15056,Q9BUB7,Q96L58,P02545,Q01082,O00192,Q6PGP7,O75844,P06280,Q9UIG0 12 +Gastrointestinal obstruction 0.3751086200728651 0.5313643515587573 0.5951663197211006 1.0 0.9211212017745286 16 P31040,P50336,P42892,P35222,Q01844 5 +Phenotypic variability 0.2989678453819656 0.5306338707020544 0.5956725196099244 1.0 0.9214681087307984 112 Q8TD16,P02545,P06753,Q9NR77,Q5THJ4,O60313,P11166,Q70HW3,Q8WVQ1,Q13868,Q9H061,Q13813,P00403,P03886,P07602,P00846,P52732,O43707,Q9Y4W6,Q6P4A7,Q9H9S5,O95470,Q9NWS8,P49792,Q8WWY3,Q9NQT5,Q9NWH9,P07196,Q9UEY8 29 +Abnormal talus morphology 0.3561543895167234 0.5301620664082456 0.5959995692310698 1.0 0.9216672207044196 20 O75844,Q9UHX1,P98175 3 +Abnormality of complement system 0.5272835361186823 0.5296991860021112 0.5963205124197861 1.0 0.9218567602178132 4 Q03252 1 +Abnormality of thyroid physiology 0.3022088167393643 0.5276533008029716 0.5977399912632206 1.0 0.9228887104457144 86 Q13045,Q8N3U4,O76024,P42224,O00192,Q14683,O60313,O60566,Q13868,P55265,O14654,P00813,Q96RR1,Q6PGP7,Q96L73,P03886,P00403,O95155,Q15046,Q15056,Q7LG56,O95470,O00443,P35222,P31749,P04066,P27635,Q13423,Q9UIG0 29 +Short palpebral fissure 0.3485067960983272 0.5275921476420176 0.5977824442525501 1.0 0.9228887104457144 27 P55795,Q15555,Q9UHX1,P98175,P02545,Q13868,O15287,O75844 8 +Abnormality of the knee 0.3018933484498816 0.526893424459554 0.5982676004032759 1.0 0.9230244153632212 101 Q86XL3,Q7RTS9,Q8TD16,P06753,O00192,Q9NR77,P16278,Q8WVQ1,Q8N0X7,Q96L58,O95831,Q6ZXV5,O00754,Q15056,P23786,P08236,O75431,P51798,Q9NX62,Q01082,Q96HY6,Q9NUQ7,Q9UIG0 23 +Multiple cafe au lait spots 0.3819472538668896 0.522297474423112 0.601463227380219 1.0 0.9261098799323648 15 O15287,O60566,Q15437 3 +Proximal tubulopathy 0.3369324944651627 0.5218207152124535 0.601795165098308 1.0 0.9261188187359424 31 P03886,O43676,Q7LG56,O75306,O75251,O75380,Q96CU9 7 +Gait imbalance 0.3534075481317438 0.5216662376797359 0.601902735892935 1.0 0.9261188187359424 23 Q9NR77,Q7LG56,Q15056,Q9UIG0 4 +Intestinal pseudo obstruction 0.3897529353891037 0.5214304923200198 0.6020669144396991 1.0 0.9261188187359424 14 P03886,Q96RR1 2 +Intractable diarrhea 0.5243051942936456 0.5195951671281033 0.6033457672373026 1.0 0.9274719749757676 4 Q6PGP7 1 +Recurrent viral infections 0.3728164422305071 0.5186932497549638 0.6039746697015111 1.0 0.9280967516316158 16 Q13432,P00813,Q9Y448,P42224 4 +Generalized abnormality of skin 0.3139809187441338 0.5179612124037177 0.6044853320526062 1.0 0.9280967516316158 245 P22830,Q14108,P98175,O15118,Q8IZA0,O43772,Q8WVM7,P02545,Q13126,P39210,O00192,Q9UBM7,P06280,P16278,P11166,P35579,Q8NCH0,P49748,Q96L58,Q9Y487,Q96JJ3,O75787,Q14739,P00813,Q969N2,P10619,P50336,O14936,P03886,O95155,Q15056,P00846,Q03252,O75431,P51798,P78536,Q9UQE7,P04066,P61916,O75306,Q15437,Q14331,Q01082,O75844 44 +Macular atrophy 0.4459283290054713 0.5178669830098961 0.6045510796619111 1.0 0.9280967516316158 7 Q8WWY3,P04439 2 +Uplifted earlobe 0.4875034331227587 0.5171298479168178 0.6050655189273406 1.0 0.9282731813982674 2 Q9BZK7 1 +Exercise induced myalgia 0.3995604801260474 0.5151391428509627 0.6064557917427935 1.0 0.9292256541918036 12 P23786,P02545,Q13049,P49748 4 +Abnormality of toe 0.2959097244661355 0.5145140453691183 0.6068926431171997 1.0 0.9293095846833715 194 Q13045,Q99720,O75175,Q8WVM7,O75419,Q71SY5,Q8N201,P02545,Q8N3R9,P39210,Q9Y366,Q9UBM7,O00192,Q9NR77,A2RRP1,Q9UHX1,Q8WVQ1,Q8N0X7,Q96L58,Q14739,P00813,Q5H8A4,O14936,P55011,O95155,Q15056,Q15233,O15078,P23786,Q8WXW3,O75431,O75530,O96028,O15287,P11274,P31749,Q9UQE7,Q9NX62,Q93009,Q5TAQ9,O00764,O60826,O75844,P07196,Q9UIG0 45 +Cephalohematoma 0.4864048338368482 0.5130654330870927 0.6079055503923936 1.0 0.9302364934938476 2 P17301 1 +Myalgia 0.3081631005680713 0.5127204795969388 0.608146861896774 1.0 0.9302364934938476 48 P20700,P49748,P23786,Q9NZ08,Q14739,P02545,Q9H9S5,O00192,Q96RR1,Q13049,P06280 11 +Weakness due to upper motor neuron dysfunction 0.2811794924250775 0.5110914579422832 0.6092870170221949 1.0 0.9310610878336532 160 P07942,Q7RTS9,O75298,Q7KZN9,P11166,O60313,Q9UBX3,Q8N0X7,Q96L58,O75787,O95831,O75251,Q9H6K4,Q6DKK2,P00403,P03886,P50336,P20700,O00754,O95155,P07602,O15078,P00846,Q7LG56,Q9Y4W6,Q9H9S5,Q96CU9,P31749,Q15051,Q13423,Q9NZ08,O75306,O43681 33 +Gonadal neoplasm 0.3321617624135111 0.5103683976064952 0.609793392665714 1.0 0.9311555309239226 32 P20585,Q13423,P51809,Q92878,P35222,Q01844,P02545,P48735,P31749,Q96L73 10 +Colpocephaly 0.4175858597809961 0.5085006519343191 0.6111022820154133 1.0 0.9311555309239226 9 Q8IY37,Q8N3U4,P53701 3 +Laryngeal stenosis 0.539562483205883 0.5084303676034534 0.6111515605678397 1.0 0.9311555309239226 3 Q96HY6 1 +Abnormality of the distal phalanx of the thumb 0.4699594177009272 0.5073298539606086 0.611923394801928 1.0 0.9318340571648356 6 Q9Y448 1 +Irritability 0.2996599159819478 0.5072226412937412 0.6119986103867179 1.0 0.9318340571648356 82 P11166,P07602,P50897,P00846,Q9NZ08,O43772,O95831,P25705,O43707,Q01082,Q8N1F7 11 +Restrictive behavior 0.4949299379014003 0.5052531398655472 0.6133810510792841 1.0 0.9330218475827932 5 Q01082 1 +Hepatocellular carcinoma 0.3511439115288908 0.5037720495540746 0.6144215711057157 1.0 0.9336877177659454 22 P50336,Q13043,P11717,P16930,P54277,Q9NWH9,P35222 7 +Brain imaging abnormality 0.3138764254813556 0.5029349378314578 0.6150100163015328 1.0 0.9338755887560544 44 P03886,P11166,Q9Y6N5,P07602,Q15046,O75306,Q93009,Q9P0J1,P31749,P00403 10 +Facial hemangioma 0.494226738046001 0.5027995778069178 0.6151051905098872 1.0 0.9338755887560544 5 O60826 1 +Emg abnormality 0.2993324003924591 0.5010245158279588 0.6163538693167245 1.0 0.9338755887560544 83 Q9NR77,P07602,P51114,Q7Z406,Q7LG56,Q14331,P02545,P06753,Q9H9S5,P39210,O43681,P09493,O14773,Q96RR1,Q13049,P07196 16 +Hypersplenism 0.4155881348714555 0.4999683569148907 0.6170973584944275 1.0 0.9340884120272328 9 P07602 1 +Cerebral hypoplasia 0.3691602226811827 0.498615378747768 0.618050368971004 1.0 0.9346210821321338 16 Q9UBM7,Q86XL3,O60566,P35606 4 +Emg chronic denervation signs 0.377377757534147 0.498147984338686 0.6183797416756835 1.0 0.934779154193266 15 P07602,O43681 2 +Abnormal lactate dehydrogenase level 0.3509478678102218 0.4977730424071874 0.6186440185899662 1.0 0.934779154193266 19 P23786,O43505,Q9H9S5,P10253,P41440 5 +Weight loss 0.298238035399096 0.4970251518411129 0.6191713147499711 1.0 0.9350955799945128 80 Q99720,P07602,Q13423,Q9NZ08,Q14203,P02545,P06753,P42892,O75844 9 +Lower extremity joint dislocation 0.2992464110627274 0.4956776385447564 0.620121866311065 1.0 0.9360193435953672 85 Q8TD16,P02545,P06753,O00192,Q9UBM7,Q9UHX1,Q8WVQ1,Q96L58,Q9Y487,Q6ZXV5,P55011,Q15056,Q9H9S5,O15287,O96028,P31749,Q9UQE7,Q9NX62,Q9NQT5,O75844,Q9UIG0 21 +Aplasia hypoplasia of the sternum 0.5164135507431182 0.4931466165770279 0.6219089944338307 1.0 0.9360193435953672 4 O60566,P98175 2 +Branchial anomaly 0.4138115188641769 0.4924141243486762 0.6224266163658152 1.0 0.9360193435953672 9 Q9UHX1 1 +Epiphyseal stippling 0.3947151516954586 0.4920790846998732 0.6226634372668065 1.0 0.9360193435953672 12 O00116,Q9UBM7,Q14739 3 +Abnormal cranial nerve physiology 0.2968587032941825 0.4920527801490122 0.6226820321448197 1.0 0.9360193435953672 77 Q9NR77,Q9UHX1,P07602,O95155,Q9NZ08,Q7LG56,Q14203,P02545,P06753,Q9H9S5,P51798,Q96RR1,P48735,Q13049,P07196 15 +Abnormality of the spinocerebellar tracts 0.5341058535903934 0.4906479472522619 0.6236754681386845 1.0 0.936039562022765 3 O00754 1 +Diffuse mesangial sclerosis 0.3493758740579185 0.4887522274071827 0.625017123341445 1.0 0.936039562022765 18 P00813,O43707 2 +Pigmentary retinopathy 0.3013497900892828 0.4874883860582029 0.6259122712195127 1.0 0.936039562022765 58 P03886,Q15555,O15078,P00846,Q7LG56,O75306,O75251,Q96CU9,Q9H9S5,Q8NHS3,Q7KZN9,Q13049 12 +Absent toe 0.3444844399104809 0.4870951132014594 0.6261909293469392 1.0 0.936039562022765 26 P55011,Q9UHX1,P02545,Q8N3R9,O96028,Q5H8A4 6 +Posterior fossa cyst 0.4892832380429465 0.4856649489049047 0.627204738976362 1.0 0.936039562022765 5 Q9H9S5,Q9UHX1 2 +Polymicrogyria 0.2978103163933458 0.4839071730675197 0.6284517494522319 1.0 0.936039562022765 83 Q05639,Q01105,Q8TD16,Q71SY5,Q96EK5,Q16625,Q9Y487,Q15392,Q10713,Q6ZXV5,Q9NXR1,P55011,P23786,Q8WXW3,O43505,Q9UBB6,Q9H9S5,Q96N66,Q14139,Q6PJT7,Q8NAT1,P42356,Q9NUQ7 23 +Bilateral polymicrogyria 0.4243475360022659 0.4830473809542323 0.6290620942967711 1.0 0.936039562022765 8 Q05639,Q01105,Q96JM3,Q00610,P42356 5 +Broad phalanx of the toes 0.4624164867288763 0.479936927869332 0.6312722420994956 1.0 0.9366835441017262 6 Q71SY5 1 +Germ cell neoplasia 0.3887229405543158 0.4799008610910116 0.6312978889236209 1.0 0.9366835441017262 13 P20585,P51809,P31749,P35222,Q96L73 5 +Arterial thrombosis 0.4233334359163243 0.4789977307826549 0.6319402429897518 1.0 0.9369948395232924 8 Q9NZ08 1 +Hepatic encephalopathy 0.5115532822910323 0.4771015517309695 0.6332898097706936 1.0 0.9381248791853404 4 A2RRP1 1 +Rimmed vacuoles 0.3806159568516514 0.4751736184272458 0.6346632292902972 1.0 0.9393647908265094 14 P22626,Q8WXH0,P50402,P02545,P43243,Q13642 6 +Complete atrioventricular canal defect 0.529032035094399 0.4743261848837116 0.6352673217777214 1.0 0.9397618376152284 3 Q9UHX1 1 +Carcinoma 0.4859220819517434 0.474131688710425 0.6354060025364854 1.0 0.9397618376152284 5 P28340 1 +Otitis media 0.2976336775554539 0.4728337311268049 0.6363318068363502 1.0 0.9403483473290528 64 Q13432,Q13045,O00754,Q15056,Q14739,Q01082,P51798,O00192,Q9UBM7,P00813,O96028,Q9UIG0 12 +Psychosis 0.3202005404407674 0.4727840311666023 0.6363672680193131 1.0 0.9403483473290528 34 P03886,O15118,P61916,Q96RR1,Q6DKK2,P50336 6 +Abnormal arachnoid mater morphology 0.4089613125097961 0.4719576592289057 0.6369570108003493 1.0 0.9405590178548532 9 Q9UHX1 1 +Abnormal phalangeal joint morphology of the hand 0.3069172239352116 0.4705966568310403 0.6379287954946153 1.0 0.941658105824854 46 O95155,Q8WVQ1,P27635,O75844,P57740,Q9H4L7,O76024,O75419,P02545,Q71SY5,O75530,Q9BUB7,Q9Y619,P11274,Q15042,Q96L73 16 +Myositis 0.392930128229398 0.4699583427222495 0.6383847799256444 1.0 0.941658105824854 11 P28070 1 +Macroorchidism 0.4846670566510426 0.469850160656438 0.6384620741508407 1.0 0.941658105824854 5 Q06787,P38159,P31749 3 +Chondrosarcoma 0.5090704575753942 0.4689797038177566 0.6390841435179477 1.0 0.9421033681812392 4 P48735 1 +Abnormality of female external genitalia 0.3184346717928118 0.4686408489580079 0.63932637383075 1.0 0.9421033681812392 36 Q9UQE7,O95155,P51809,Q15392,O75419,P02545,Q9UBM7,Q9Y619 8 +Synostosis of joints 0.3167395719954485 0.4678180800671073 0.6399146900303929 1.0 0.9422318011949417 38 Q9UQE7,Q9UHX1,Q15056,Q8WVQ1,Q96L58,Q9H9S5,O96028,Q9UIG0 8 +Recurrent fever 0.3547505645427173 0.466936518976444 0.6405452965933316 1.0 0.942563012434836 17 Q9NR77,P28070 2 +Abnormality of the fetal cardiovascular system 0.458542117756024 0.4660626719325782 0.6411706413069636 1.0 0.9431845426253432 6 O60826 1 +Abnormal gastrointestinal motility 0.3191411842629664 0.4648732506936181 0.642022227315834 1.0 0.9441383830179368 34 P03886,P11802,P16930,Q96RR1,P35637,Q7LG56,Q01844,Q9UBM7,P06280,P50336,P00403 11 +Increased csf lactate 0.2984032779292207 0.4639918447807592 0.6426535884928828 1.0 0.9447678664113972 60 P03886,O43676,P00846,O95831,P39210,O75380,Q7KZN9,Q96CU9 8 +Central hypoventilation 0.4193367773962161 0.4631401407760301 0.6432639192060403 1.0 0.9453660444498638 8 P06753,Q14203 2 +Microglossia 0.5070594501250272 0.4624391443669849 0.6437664335923694 1.0 0.945805443219646 4 Q03252 1 +Obsessive compulsive behavior 0.3116918743602941 0.46182258401751 0.6442085540508127 1.0 0.9458679923576272 42 Q9UQE7,Q15056,Q93009,Q01082,O75503,P11274,Q6DKK2 7 +Abnormal glial cell morphology 0.2974085532010314 0.4612445213980319 0.6446231830851314 1.0 0.9458679923576272 62 P20700,P20585,O00754,P54277,P35637,P00846,O75306,P49792,O95831,Q10713,Q92734,P04062,P48735,Q7KZN9,P49770,Q96L73 16 +Intracranial hemorrhage 0.3311496285221024 0.4607235221526953 0.6449969768062873 1.0 0.9461177245008892 30 P23786,O75844,Q9NUN5,P05067 4 +Increased nuchal translucency 0.3535117280425639 0.4599903921039502 0.645523116877154 1.0 0.9464964152290354 17 Q9UQE7,Q15056,Q9UBM7,Q9UIG0 4 +Chronic infection 0.392845814638359 0.4586398519154652 0.6464928135631547 1.0 0.9471205243705412 10 Q6UN15,O75533,Q14980,P40763,P51798,Q9BZK7 6 +Osteosarcoma 0.3418196941705591 0.4583518447861744 0.6466996823386544 1.0 0.9471205243705412 25 Q13126 1 +Abnormality of the septum pellucidum 0.3035856029802207 0.4564488486738047 0.6480672456273906 1.0 0.948226854669548 47 Q96N66,Q14139,P55011,Q6PJT7,Q15392,Q8N3U4,O43505,Q71SY5,Q9UBB6,Q8NAT1,Q9H9S5,O96028,Q9NUQ7,Q96L73 14 +Hyperthyroidism 0.3835978997035126 0.4552599154224205 0.6489222604015841 1.0 0.9487333040310312 13 O00192,Q96RR1,Q7LG56 3 +Cerebellar dysplasia 0.4803166130968031 0.4551158990236852 0.6490258604507528 1.0 0.9487333040310312 5 Q9H9S5 1 +Abnormal systemic arterial morphology 0.2747777881816539 0.4547681987508402 0.6492760110999507 1.0 0.9487464129356744 154 P55263,O15118,P02545,P06753,P10253,Q8N3R9,O00192,Q9UBM7,P05067,P16278,Q9UHX1,Q96L58,O14678,Q6ZXV5,P10619,P03886,P55011,O95155,P07602,P00846,Q9Y448,P11274,P61916,Q01082,O75844 25 +Coarse hair 0.3435509868965761 0.4545359059888478 0.6494431546262924 1.0 0.9487464129356744 18 Q9Y487 1 +Abnormally lax or hyperextensible skin 0.2977210891389582 0.4541739391639559 0.6497036387747444 1.0 0.9488286641691503 50 Q9Y3D3,Q15555,Q8NCH0,Q9UHX1,Q15056,Q96L58,Q9Y487,O75787,O75530,Q9UIG0 10 +Abnormal morphology of the olfactory bulb 0.5220854357538327 0.4523273666140015 0.6510331637305673 1.0 0.9498747603943316 3 Q8N3U4 1 +Single naris 0.5220854357538327 0.4523273666140015 0.6510331637305673 1.0 0.9498747603943316 3 Q8N3U4 1 +Chronic mucocutaneous candidiasis 0.4163833046872587 0.451529418036468 0.6516080275325029 1.0 0.9502608066310648 8 P02786,Q9Y448 2 +Respiratory distress 0.297324411510837 0.448848250122708 0.6535411294109617 1.0 0.9502608066310648 58 P03886,Q9UHX1,P07602,P23786,P00846,O95831,P10253,Q9Y366 8 +Duplication involving bones of the feet 0.3384959567989873 0.4485425574821162 0.6537616795410088 1.0 0.9502608066310648 26 O95155,O15078,Q14739,O00192,Q9UBM7,O96028 6 +Addictive behavior 0.4533409472905942 0.4476564828212355 0.6544011326191785 1.0 0.9502608066310648 6 Q6UN15,Q14980,Q9BZK7,P40763 4 +Diffuse alveolar hemorrhage 0.4533409472905942 0.4476564828212355 0.6544011326191785 1.0 0.9502608066310648 6 Q6UN15,Q14980,Q9BZK7,P40763 4 +Decreased facial expression 0.3168041781428236 0.447510133210817 0.6545067730947238 1.0 0.9502608066310648 34 O75787,Q14203,Q7LG56,P06753,Q9Y448,Q9H9S5,Q96RR1,Q13049 8 +Impaired visuospatial constructive cognition 0.4028956533892903 0.4467344999337528 0.6550667688879976 1.0 0.9506855949476968 9 P03886,P11166,P00403 3 +Abnormal csf metabolite level 0.2923581145557659 0.4442609040758286 0.6568539637003474 1.0 0.951648850259164 68 P03886,P11166,O43676,P00846,O75306,O95831,O75251,Q01082,P39210,O75380,Q9HC21,Q7KZN9,Q96CU9,Q9NWS8,P00403 15 +Abnormal pulmonary interstitial morphology 0.3197208508291553 0.4438904223981667 0.6571218093916416 1.0 0.951648850259164 33 Q8IZA0,P14174 2 +Dysmetric saccades 0.4265430103050354 0.4438320546754435 0.6571640112936641 1.0 0.951648850259164 7 Q9Y4W6,O14773 2 +Esophageal atresia 0.4140302613480094 0.442346696739719 0.658238344561727 1.0 0.9516576996207452 8 Q9Y2W2,Q15029,Q8NCM8,Q9P2D1,Q15149,Q96GM5,P25490 7 +Nail dysplasia 0.3194633417124081 0.4420267348082107 0.658469859898942 1.0 0.9516576996207452 33 O96028,P42892,O75530 3 +Dystrophic toenail 0.4763222970858741 0.4417382125902926 0.6586786544332779 1.0 0.9516576996207452 5 O75844 1 +Malrotation of small bowel 0.4761105300978189 0.4410330763232685 0.6591890515371597 1.0 0.9516576996207452 5 O96028 1 +Coma 0.313228102150841 0.4406132038780654 0.6594930422296916 1.0 0.9516576996207452 38 Q13423,P23786,O43772,P31751,P05067,P50336 6 +Increased head circumference 0.280095131333177 0.4392294977049663 0.6604952533882638 1.0 0.9526033700582632 132 P07942,P55263,Q8TD16,P02545,Q8N3R9,P11166,P49748,Q15392,Q14739,Q969N2,O00754,P55011,P07602,O43505,Q9H9S5,P08236,P51798,O75530,Q13555,Q15437,Q8NAT1,Q01082,P15291,O60826,O75844 25 +Foam cells 0.4507615322857202 0.4386247017235195 0.6609334954087802 1.0 0.9526033700582632 6 P16278,O15118 2 +Rapidly progressive 0.3857293548794088 0.4375121979817342 0.6617399317801953 1.0 0.9529301093841238 11 Q14108,Q8NHS3 2 +Abnormality of the musculature of the hand 0.3140432914617299 0.4353834526512719 0.6632841193107328 1.0 0.9542883454403976 36 Q9NR77,Q8TD16,P46783,Q14203,P07196 5 +Duodenal adenocarcinoma 0.4644328481186383 0.4344650466137775 0.6639507716415509 1.0 0.9542883454403976 2 P43246 1 +Flexion contracture of digit 0.29244183882434 0.4329917094032611 0.6650207928400604 1.0 0.9542883454403976 80 O95155,Q8WVQ1,Q8N0X7,Q7RTS9,Q71SY5,P02545,P06753,P42892,O75530,O60826,O75844,P11274,P07196 13 +Developmental regression 0.278005941380885 0.4327305757890779 0.6652105141999249 1.0 0.9542883454403976 134 Q86VD7,Q9UIG0,O14773,O75503,P06280,P16278,O95831,O75251,Q969N2,Q13813,O14936,P03886,Q15046,P07602,Q15056,P00846,Q96F07,P17480,P49792,P55795,Q9NZ08,O75306,Q01082,O43681,P49770,Q9GZY8 26 +Abnormal cornea morphology 0.283649911717456 0.4326309118316979 0.665282928691183 1.0 0.9542883454403976 177 Q13045,Q9HD42,Q71SY5,Q8N201,P02545,Q8N3R9,P39210,Q9Y5Z9,O00192,Q9UBM7,Q96EK5,P06280,Q16625,P16278,O60566,O43395,Q8NCH0,Q96L58,Q14739,Q13868,Q969N2,Q8WYQ5,Q5H8A4,P10619,Q96L73,O00754,P55011,Q15056,O15078,Q9NWM8,O43505,P52732,P34059,Q9H9S5,P08236,O15287,O96028,P04062,P31749,Q15051,Q9UQE7,Q15555,P04066,Q8WWY3,O75569,Q9NZ08,Q8NAT1,O75844,O75175,Q9UIG0 50 +Overlapping toe 0.3389814026680914 0.4321079925575825 0.6656629259606388 1.0 0.9542883454403976 23 Q71SY5,O60826,Q9UHX1 3 +Thoracolumbar kyphosis 0.4487541975199186 0.4316414826914323 0.6660020038743222 1.0 0.9542883454403976 6 O00754,P08236,P04062 3 +Abnormality of coordination 0.3313216426250223 0.430742686619796 0.6666554770484234 1.0 0.9542883454403976 355 Q99720,Q86VD7,Q14108,O15118,Q7RTS9,P06753,O75298,O75027,P39210,O14773,O75503,Q7KZN9,P05067,Q9NR77,P16278,P11166,Q8N0X7,Q9Y487,O43676,O75787,O95831,O75251,Q8NHS3,Q9BPX6,Q96RR1,Q969N2,Q9BUB7,Q6DKK2,O14936,P03886,P20700,O00754,P07602,Q8IV08,P50897,O15078,Q15056,Q8WXW3,P00846,Q7LG56,Q03252,Q96F07,Q9Y448,Q9H9S5,O75530,O96028,P41440,Q96CU9,Q15051,O00584,P61916,Q9NZ08,Q15437,Q01082,O43681,Q9NWW5,O75380,Q9NUN5,P07196 59 +Microretrognathia 0.3393897050488572 0.4304240235252216 0.6668872230719649 1.0 0.9542883454403976 18 Q9UHX1,Q8NCH0,Q8WVQ1,Q8N201,Q9BUB7 5 +Low set posteriorly rotated ears 0.2929801571097425 0.4300683648065435 0.6671459115020526 1.0 0.9542883454403976 83 Q9UQE7,O60566,O95155,Q15555,P98175,Q4J6C6,O15078,Q96L58,Q8WVQ1,Q8NCH0,Q15056,Q15392,Q96RK4,O75530,O96028,Q9UBM7,Q13049,Q9UIG0 18 +Ocular albinism 0.4725082565075725 0.4291029797183532 0.6678482839160584 1.0 0.9542883454403976 5 O95155 1 +Ventriculomegaly 0.2968882713906866 0.4283400223179735 0.668403584612725 1.0 0.9542883454403976 211 Q13045,Q86XL3,Q01105,Q8TD16,Q71SY5,Q5KU26,Q9HC21,Q9UBM7,Q96EK5,Q16625,P16278,Q9UHX1,Q8NCH0,Q9Y487,Q15392,O75787,Q6ZXV5,O14936,P20700,Q9Y3D3,O95155,P07602,O15078,P23786,P00846,O43505,Q03252,Q96F07,Q9Y448,Q9H9S5,P11177,O96028,Q9BX67,Q96CU9,Q969M3,Q9UQE7,O00584,P35606,O75306,Q8NAT1,Q01082,P15291,Q93009,O60826 44 +Abnormality of fluid regulation 0.2788628512851058 0.426138894529306 0.6700066402241838 1.0 0.9542883454403976 167 P22830,Q14108,P14174,Q9UBM7,P06280,P16278,P28070,Q14739,P00813,Q96RR1,P10619,Q9Y3D3,Q15056,P23786,Q7LG56,P52732,O43707,Q9Y448,P08236,Q8N1F7,Q9UQE7,Q15555,Q9NZ08,P46783,Q14331,Q01082 26 +Abnormal liver morphology 0.3150162811992016 0.4256864825989556 0.6703363131227358 1.0 0.9542883454403976 269 P22830,P55263,Q14108,O15118,Q9HC07,O43772,P14174,P02545,P10253,P39210,P54802,Q7KZN9,P16278,P11717,P11166,P49748,P28070,O43676,O75787,P15586,O75251,Q14739,P00813,Q9BUB7,Q13049,P10619,P03886,O00754,O95155,P07602,O15078,P23786,P00846,Q7LG56,Q03252,P08236,O75431,P51798,Q9BX67,Q96CU9,Q9NWS8,Q15051,P04066,P61916,Q9NWH9,O75306,Q01082,P31751,Q96HY6,O75380 50 +Abnormality of periauricular region 0.3378124111119454 0.4250067338651979 0.6708317658691312 1.0 0.9542883454403976 23 O96028 1 +Hypoventilation 0.3554570289792751 0.4249780993966222 0.6708526399983823 1.0 0.9542883454403976 16 O75380,P06753,Q9H9S5,Q14203 4 +Protruding tongue 0.3800246519602883 0.4238454171603048 0.6716785532062066 1.0 0.9545230081801964 12 P20700,Q9NRZ9,Q10713,P42356,O15111,O60826 6 +Abnormal aortic valve cusp morphology 0.3324877147263712 0.4224969690909922 0.6726623125400273 1.0 0.9553895167191844 27 Q9UQE7,Q9UHX1,Q15056,Q96L58,Q01082,Q9UIG0 6 +Schizophrenia 0.3380691402938046 0.4223280966847205 0.6727855528155895 1.0 0.9553895167191844 21 P07602,O43681 2 +Abnormality of fundus pigmentation 0.4702769229769435 0.4217753902636347 0.6731889702229696 1.0 0.9553895167191844 5 Q9Y619,O15484 2 +Abnormal thalamic mri signal intensity 0.3967104165407562 0.4214509677732198 0.6734258082450872 1.0 0.9553895167191844 9 Q96RR1,Q9GZY8 2 +High frequency sensorineural hearing impairment 0.4699607977581511 0.420741157309551 0.6739441038083356 1.0 0.9554613508550214 5 Q9NWM8,P02545,O75844 3 +Calvarial hyperostosis 0.4454995612922045 0.4204054055685315 0.6741893198738143 1.0 0.9554613508550214 6 P22626,P10644,Q15043,P31749 4 +Motor seizure 0.2890263815669454 0.4192810232126783 0.6750107637270344 1.0 0.95593048264771 115 Q05639,Q01105,Q96N67,Q71SY5,O75503,Q9Y619,P16278,P11166,O60566,Q9Y6N5,Q9UBX3,O75787,Q8NHS3,Q9NXR1,Q969N2,Q13813,Q96L73,P03886,O14936,P55011,P07602,Q15046,P00846,Q9Y4W6,Q9UBB6,Q9Y448,P04062,Q9Y3C6,Q96N66,Q14139,Q01082,P42356,Q9NUQ7,Q9GZY8 34 +Duodenal atresia 0.4195520487186898 0.4180669375973203 0.6758981773037522 1.0 0.95593048264771 7 O60566 1 +Contractures of the joints of the lower limbs 0.2943245262549128 0.4180302184694154 0.6759250235003207 1.0 0.95593048264771 55 Q99720,Q86XL3,P23786,Q8IZA0,Q8TD16,P02545,P06753,Q9H9S5,Q9HC21 9 +Abnormal endocrine physiology 0.4690296852192224 0.4177006181129762 0.6761660203277431 1.0 0.95593048264771 5 P50336 1 +Increased muscle lipid content 0.3949670923085807 0.4144082658539969 0.6785751364022969 1.0 0.9575884175103172 9 P23786,P06753,Q9Y4W6 3 +Absent brainstem auditory responses 0.5094318349183794 0.4133477841219929 0.679351825117966 1.0 0.9583934217738884 3 P07196 1 +Delayed eruption of permanent teeth 0.4675444434041258 0.4128682503586165 0.6797031438317738 1.0 0.9585980301627474 5 Q12824,Q96L73 2 +Hamartoma of the eye 0.3944079434827205 0.4121574083736853 0.680224052838017 1.0 0.9590416181851532 9 P31749,Q15437 2 +Abnormal abdomen morphology 0.3070980909107048 0.408720012264845 0.6827451457687164 1.0 0.9599747934605825 245 Q14108,O15118,Q9HC07,O43772,P14174,P02545,P10253,P39210,P54802,O00192,P16278,P11166,P49748,P28070,O43676,Q15392,O75787,O75251,P15586,Q14739,P00813,Q9BUB7,P10619,O14936,P03886,O00754,P07602,P23786,P00846,P08236,O75431,P51798,Q9BX67,P11274,Q96CU9,Q9NWS8,P04066,P61916,Q9NZ08,Q9NWH9,Q15437,Q01082,P31751,Q96HY6,O75380 45 +Focal t2 hyperintense basal ganglia lesion 0.3336885354093247 0.4076560633192643 0.6835261984148762 1.0 0.9601050363758604 25 P03886,P00846,Q7KZN9,Q96CU9 4 +Abnormal glomerular mesangium morphology 0.3355908982800436 0.4074938672442389 0.6836452975141194 1.0 0.9601050363758604 19 P00813,O43707 2 +Ankylosis 0.4657097993526646 0.4069293768555504 0.6840598590165317 1.0 0.9601050363758604 5 O75844 1 +Short sternum 0.5071888268137027 0.4065925817238387 0.6843072465884679 1.0 0.9601050363758604 3 P98175 1 +Agenesis of permanent teeth 0.4559187036528374 0.40549940119857 0.6851104584941581 1.0 0.9601050363758604 2 Q14696 1 +Abnormal number of permanent teeth 0.4559187036528374 0.40549940119857 0.6851104584941581 1.0 0.9601050363758604 2 Q14696 1 +Astrocytoma 0.3925235176358884 0.404600636420782 0.685771090665432 1.0 0.9601312035944938 9 P20585,P48735 2 +Abnormal insulin level 0.3330419946096956 0.403680040429193 0.6864480188500834 1.0 0.9605311483277138 25 O43395,Q15555,Q8WWY3,O95714,P53985,P02545,P31751,O75431,O75844 9 +Multifocal seizures 0.4642660802638682 0.402279773856589 0.687478138338457 1.0 0.961201895461374 5 Q10471,Q14683,Q9UGM6,Q6PJG6 4 +Multifocal epileptiform discharges 0.3198604569938169 0.4021881094453789 0.6875455923988139 1.0 0.961201895461374 31 Q96N66,P55011,Q9UBX3,Q96N67,Q71SY5,Q01082,O75503,Q969N2,O14936 9 +Dimple chin 0.5054945054945069 0.4015217681751513 0.6880360147166193 1.0 0.961482402212418 3 Q15910,Q2VPK5 2 +Fetal akinesia sequence 0.4639738932239887 0.4013413381613877 0.6881688324772091 1.0 0.961482402212418 5 P06753 1 +Muscular dystrophy 0.3223447380917484 0.4009556017122129 0.688452812234023 1.0 0.961482402212418 30 O60566,P22626,Q8WXH0,P50402,Q13642,O43505,Q14331,P02545,Q8NAT1,Q9H9S5,Q96T60,Q9Y5P6,Q13049 13 +Organic aciduria 0.3015641807803342 0.4006669408984027 0.6886653534975979 1.0 0.961482402212418 44 P49748,P23786,Q9NUN5,O43772,O14678,Q9NPF0,P48735,Q8NFF5,P50336 9 +Apraxia 0.2873254755483591 0.3996910185044393 0.6893841081571881 1.0 0.961482402212418 69 O96008,Q8N3U4,O14773,Q8N3R9,Q9Y619,P05067,P11166,Q8N0X7,O75787,Q10713,Q6DKK2,P55011,Q15233,O15078,Q8WXW3,Q9Y4W6,P11274,Q9NQT5,Q93009,P42356,O75175 21 +Abnormality of the skull base 0.2872956429643603 0.3993834541898663 0.6896106835752076 1.0 0.961482402212418 69 O00754,Q9UHX1,O60826,P49748,O15078,Q96L58,Q9Y487,P23786,P80404,O43505,Q14739,P15291,Q9H9S5,Q9UBM7 14 +Duplication of hand bones 0.2890915803085382 0.397896758196508 0.6907062897631737 1.0 0.9618799304034844 66 Q13045,Q9UHX1,Q8WVQ1,P98175,O15078,Q8WXW3,O60826,P46783,Q14739,Q96RK4,O00192,Q9UBM7,O96028,Q13049 14 +Hip dysplasia 0.2920670572125243 0.397653305602349 0.6908857616175794 1.0 0.9618799304034844 54 Q9UQE7,P55011,Q9UHX1,O95155,Q96L58,Q8TD16,P02545,Q93009,Q8N3R9,O96028 10 +Neoplasm of fatty tissue 0.3740802453676461 0.3970308225258048 0.6913447315574861 1.0 0.9618799304034844 12 P27635,Q9Y2U8,Q15437,O95140,P31749 5 +Nausea and vomiting 0.2704668231935849 0.395694626699558 0.6923303199344004 1.0 0.9620813223553848 153 Q8IZA0,P39210,Q9UBM7,P06280,A2RRP1,P49748,O43676,Q14203,O75251,P42892,P50336,P00403,P03886,P22695,P07602,Q15046,Q15056,P23786,P00846,Q7LG56,Q96CU9,P31749,Q68CQ7,Q13423,Q9NZ08,Q9NWH9,Q15165,O75306,Q01082,P11117,O75380,Q9UIG0 32 +Athetosis 0.3333625472431079 0.3947329654974997 0.6930399713250357 1.0 0.9620813223553848 19 Q96CU9,O00584 2 +Abnormality of blood circulation 0.2882329071430273 0.3943944994235521 0.6932898042105728 1.0 0.9620813223553848 78 P31040,O75533,Q02241,O76024,P02545,O00192,P05067,Q12824,Q9UHX1,Q9Y487,Q14739,P49257,Q9NXR1,Q9BZK7,Q9UGP8,P23786,O15484,P04062,P35222,P31749,P49792,P16930,P38435,P54277,Q9NZ08,O75844,Q9NUN5,Q9UJS0 28 +Abnormality of facial soft tissue 0.2791449160242713 0.3942575390723757 0.6933909086077512 1.0 0.9620813223553848 129 Q86VD7,P02545,P06753,P10253,Q9UBM7,O60313,Q9UHX1,P28070,O75787,Q14203,Q96RR1,Q13049,O00754,Q15056,Q7LG56,Q03252,O43707,Q9Y448,Q9H9S5,P51798,Q8N1F7,Q13555,Q15437,Q14331,Q01082,O60826,O75844,P07196,Q9UIG0 29 +Hypocalcemia 0.333248834540256 0.3940842874594666 0.6935188111057942 1.0 0.9620813223553848 19 O00192,P49748,Q4J6C6 3 +Reticulocytosis 0.3566177071665659 0.3919310472886498 0.6951091620866761 1.0 0.9633655548431552 15 P11166,Q15437,O14936 3 +Glomerular sclerosis 0.3089708563325468 0.3902661848040207 0.6963397253644912 1.0 0.9633655548431552 34 P31040,P03886,Q14108,Q8NFH4,O95470,P57740,O43707,O75431,Q8N1F7,P00403 10 +Short phalanx of the thumb 0.3764308635239523 0.3881493600634784 0.6979055057457633 1.0 0.9633655548431552 10 Q9Y448,Q8WVQ1 2 +Abnormality of the axillary hair 0.435798735221319 0.3875739089387494 0.6983313802065321 1.0 0.9633655548431552 6 Q9H7N4,P51809,Q14574,P62304,Q8IY37 5 +Kyphoscoliosis 0.2901635490389073 0.3873397130774081 0.6985047288825972 1.0 0.9633655548431552 61 Q9NR77,Q8NCH0,Q96L58,Q9HC07,Q9Y487,P02545,Q5KU26,P06753,Q9H9S5,O75844 10 +Abnormal protein o linked glycosylation 0.4998270222068623 0.3847635725675227 0.7004125900922353 1.0 0.9633655548431552 3 Q15904 1 +Chronic otitis media 0.3172694693273348 0.3845882356034316 0.7005425116026756 1.0 0.9633655548431552 31 Q13045,Q15056,O96028,O00192,Q5H8A4,Q9UIG0 6 +Degeneration of the lateral corticospinal tracts 0.3987027983398962 0.3840966734914328 0.7009067969134872 1.0 0.9633655548431552 8 O00400,P35637,O75298,Q14203 4 +Aplasia hypoplasia of the hallux 0.3309294156817066 0.3837275075092781 0.7011804225152154 1.0 0.9633655548431552 23 P55011,Q9UHX1,Q8N3R9,O96028,Q5H8A4 5 +Sandal gap 0.3141354338750763 0.3824488747336734 0.7021284437960356 1.0 0.9637572460712645 32 A2RRP1,Q8WVQ1,Q96L58,O95714,Q14739,O75431,O75530,Q9Y366,P11274 9 +Lower limb asymmetry 0.3977100428160982 0.3804227940571589 0.7036315970620104 1.0 0.9645357025212868 8 Q15555,O95155 2 +Microdontia 0.3165710859586759 0.3798724516780033 0.7040400975549794 1.0 0.9645649774708012 31 Q9UQE7,Q15555,Q15056,Q96L58,Q9Y487,Q9Y366 6 +Solitary median maxillary central incisor 0.4979651357051135 0.3793278358849589 0.7044444314790799 1.0 0.9645649774708012 3 Q8N3U4 1 +Abnormal clavicle morphology 0.3305285795334245 0.3782311157531486 0.7052589123687312 1.0 0.964843387492566 21 Q14739,P02545,O75419,O75431,O75844 5 +Abnormal circulating igm level 0.3298625373160775 0.3763705434737268 0.7066414417177656 1.0 0.9651557051997762 18 P00813,Q969N2 2 +Exercise intolerance 0.3054030735884266 0.3758318326477712 0.7070419207900109 1.0 0.9651557051997762 37 P03886,P23786,Q7LG56,P06753,Q8NFF5,Q96RR1,Q9Y2R0,P13807 8 +Abnormality of the bladder 0.2763125688213015 0.3752626026151833 0.7074651760324338 1.0 0.9651557051997762 131 Q99720,Q86XL3,O75298,O00192,Q9NR77,P11166,Q9UHX1,Q8NCH0,Q8N0X7,Q96RR1,P50336,P20700,P07602,Q15056,Q7LG56,Q9UQE7,P35606,O43681,P07196,Q9UIG0 20 +Epidermoid cyst 0.4465806097225991 0.3747822860409635 0.7078223893524378 1.0 0.9651557051997762 2 Q9H488 1 +Non midline cleft palate 0.4465806097225935 0.3747822860409465 0.7078223893524505 1.0 0.9651557051997762 2 O15111 1 +Bilateral cleft lip and palate 0.4465806097225935 0.3747822860409465 0.7078223893524505 1.0 0.9651557051997762 2 O15111 1 +Bilateral cleft palate 0.4465806097225935 0.3747822860409465 0.7078223893524505 1.0 0.9651557051997762 2 O15111 1 +Cerebral visual impairment 0.2841560574836365 0.3727743385124724 0.7093164033557886 1.0 0.9660590053910756 73 Q05639,Q01105,Q9HD42,Q8N3U4,Q96N67,Q71SY5,Q96RR1,Q969N2,P00403,P03886,P20700,P55011,Q7LG56,Q9UBB6,Q96CU9,Q96N66,Q14139,Q6PJT7,P35606,Q9BSJ2,Q9NUQ7 21 +Stage 5 chronic kidney disease 0.3152652150502645 0.3710875329934741 0.7105723363894489 1.0 0.9672025914475012 31 Q15051,O15078,P23786,O43707,Q8N1F7 5 +Abnormality of t cell physiology 0.3369612738878327 0.369580195720085 0.7116953094416774 1.0 0.9681639645712748 17 P00813 1 +Abnormal anatomic location of the heart 0.3587143212415785 0.3688065325631871 0.712271935130705 1.0 0.9683437873136946 14 P02545,O75844,O15078 3 +Premature ovarian insufficiency 0.3278244988825059 0.3681757802643169 0.7127421684516313 1.0 0.9683437873136946 24 P02545,Q15051,O15078 3 +Finger syndactyly 0.2974725441965845 0.3676224397680365 0.7131547802916864 1.0 0.9683437873136946 44 Q96RK4,O60826,P98175,O15078,O15287,Q71SY5,O75530,Q9Y366,Q9UBM7,Q9Y619,Q96EK5,Q13049,P31749,Q96L73 14 +Abnormal macrophage morphology 0.4289609308956308 0.3650554162636112 0.7150700402516976 1.0 0.9697337203355274 6 P16278,O15118 2 +Occipital meningocele 0.4288019595949688 0.3645382705284832 0.7154561010980707 1.0 0.969872958518884 6 O00192 1 +Patent ductus arteriosus 0.2885419511487621 0.3636816374153638 0.7160957569577191 1.0 0.9699891074676408 97 Q9UQE7,Q9Y3D3,Q9UHX1,O60826,Q15233,Q9UBM7,O95155,Q15056,Q969N2,Q15392,P02545,Q6ZXV5,P42892,O75530,O00192,Q6PGP7,O75844,Q9UIG0 18 +Abnormal labia minora morphology 0.3930676692330722 0.3634124256771996 0.7162968210297045 1.0 0.9699891074676408 8 O95714,Q9Y619,O75419 3 +Abnormal erythrocyte morphology 0.2919453644418786 0.3633054537481434 0.716376719782428 1.0 0.9699891074676408 209 P22830,Q14108,O75027,P00390,Q7KZN9,P06280,P11166,Q9UBX3,P28070,Q96JJ3,O75251,O14678,P00813,Q969N2,P50336,P03886,P07602,O43707,O75431,P41440,P48735,Q96CU9,Q15437,Q9NUN5 24 +Aortic arch aneurysm 0.3697668540703803 0.3605757534245732 0.7184166175830788 1.0 0.9711609744269544 10 O95155,Q15056 2 +Abnormal superior cerebellar peduncle morphology 0.4913107303251259 0.3601899388241799 0.7187050981395084 1.0 0.9711609744269544 3 O15078 1 +Prominent eyelashes 0.3810394713533784 0.359558486907757 0.7191773326494959 1.0 0.9712881446579998 9 Q12824,P20700,Q8TAQ2,P51532 4 +Abnormality of iron homeostasis 0.4505601515950284 0.3592256999906368 0.719426252186967 1.0 0.9712881446579998 5 Q6PGP7 1 +Vitreous hemorrhage 0.4495496517631162 0.3561321316473063 0.7217416150614846 1.0 0.9718728731355314 5 O15484,P35222 2 +Scleroderma 0.4259657975833618 0.3553619081389392 0.7223184818657415 1.0 0.9721816651471248 6 P02545,Q9Y2U8,Q14739 3 +Vitritis 0.4893528007580539 0.3546468212074319 0.7228541949338791 1.0 0.9721816651471248 3 P04439 1 +Truncus arteriosus 0.3661880442337078 0.3529294282109412 0.7241413481396437 1.0 0.9731367583770496 11 P11274,Q9UHX1 2 +Episodic ataxia 0.4484974562979136 0.3529230945991189 0.7241460965069588 1.0 0.9731367583770496 5 P11166 1 +Abnormal circulating androgen level 0.35522443049471 0.3525348121384316 0.7244372157202101 1.0 0.973246528317958 14 P31749,Q8IY37,Q13423,P51809 4 +Absent thumbnail 0.4707493634144741 0.3507740079187312 0.7257578983804929 1.0 0.974587872203312 4 O14936 1 +Macroglossia 0.3012107123038245 0.3499437716270308 0.7263808963723313 1.0 0.974587872203312 38 P16278,O00754,P04066,Q15056,Q15437,Q9H9S5,P10253,P31749,Q9UIG0 9 +Hyperphenylalaninemia 0.4383411150782698 0.3486446653965739 0.7273560910807881 1.0 0.974587872203312 2 P09417 1 +Distal sensory impairment of all modalities 0.4466735354433759 0.347390087631806 0.7282982791420713 1.0 0.974587872203312 5 O15269 1 +Hypohidrosis 0.3639824856842104 0.3437351146401907 0.7310455008289156 1.0 0.9750539951195598 11 P20700,P06280,O14936,Q9Y2V7 4 +Myotonia 0.3768226941562043 0.3434791280288637 0.7312380402392222 1.0 0.9750539951195598 9 P50402,Q8WXH0,P02545 3 +Skeletal muscle atrophy 0.2811816576599381 0.3431844008550627 0.731459739190838 1.0 0.9750698244463064 185 Q99720,P55263,Q8TD16,Q71SY5,P02545,P06753,O75298,Q13126,P39210,Q9HC21,Q9NR77,P16278,O60313,Q8N0X7,Q7Z406,Q9BQT8,Q14203,O95831,Q13049,Q6DKK2,O15078,O43505,Q7LG56,Q03252,Q9H9S5,Q68CQ7,Q15165,Q14331,Q8NAT1,Q96RK4,P07196 31 +Broad neck 0.3636675815203747 0.3424286368483529 0.7320283405779182 1.0 0.9755479491441312 11 P11166,O60826 2 +Cerebellar hypoplasia 0.2708036506264065 0.3418219520425891 0.7324848882690451 1.0 0.975876512553398 135 P07942,P98175,Q9HD42,Q8TD16,Q8N3U4,Q8N201,Q9HC21,Q9UBM7,Q16625,O60566,Q9Y487,P80404,Q10713,Q9NXR1,Q969N2,Q5H8A4,Q96KP1,O14936,Q15233,O15078,P23786,Q8WXW3,O43505,Q9Y4W6,P11177,Q9H9S5,Q9BX67,Q9Y3C6,P55795,P25705,Q8NAT1,P15291,P42356,O60826 34 +Axonal degeneration 0.3977311487906754 0.3413109191775249 0.7328695286129898 1.0 0.9760710218009064 7 Q9BQT8,Q6DKK2 2 +Subcutaneous hemorrhage 0.2899327993584968 0.3410423797125699 0.7330716777602766 1.0 0.9760710218009064 47 P35579,Q14108,Q8NCH0,Q96L58,Q86YV9,Q13126,P51798,O00192 8 +Abnormal pulmonary valve physiology 0.2991257112198854 0.3400780002486543 0.7337977887223901 1.0 0.9760710218009064 39 Q9UQE7,P55263,Q15056,O75306,P00813,O60826,Q9UIG0 7 +Cutis laxa 0.3009781012088747 0.3393791974533193 0.7343240876987394 1.0 0.9760710218009064 36 Q9Y3D3,Q8NCH0,Q15056,Q96L58,Q9Y487,O75787,O75530,Q9UIG0 8 +Type ii transferrin isoform profile 0.4439227651633245 0.3391174216914633 0.7345212746369205 1.0 0.9760710218009064 5 O75787,Q9Y2V7 2 +Abnormality of corneal thickness 0.3310669924810623 0.3385777707684171 0.7349278308811489 1.0 0.9760947763954202 17 Q15051,O43395,Q15555,Q8WWY3,O15078 5 +Abnormal renal medulla morphology 0.3605463210748553 0.3379212801960834 0.7354225106362708 1.0 0.9764309734076432 12 Q15051,O15078 2 +Downturned corners of mouth 0.2936073379656718 0.336899715408291 0.7361924998627991 1.0 0.9764650426905724 44 Q05639,Q9UQE7,Q9UNW9,O95714,Q96A33,Q9Y2U8,Q8N201,Q8IY37,O96028,Q969N2,Q5H8A4,O75175,Q14683 13 +Overlapping fingers 0.3637413651188803 0.3362147390963038 0.7367089390301587 1.0 0.9764650426905724 10 Q71SY5 1 +Red eye 0.3229297221793307 0.3352268885330829 0.7374539402184281 1.0 0.977173783916463 20 P02786,P28070,Q9NZ08 3 +Aplasia hypoplasia of the cerebellum 0.2653954831875003 0.3330714881586177 0.7390803209407286 1.0 0.9782131163234308 151 P07942,P98175,Q9HD42,Q8TD16,Q8N3U4,Q8N201,Q9HC21,Q9UBM7,Q16625,O60566,Q9Y487,P80404,Q10713,Q9NXR1,Q969N2,Q5H8A4,Q96KP1,O14936,P20700,Q15233,O15078,P23786,Q8WXW3,O43505,Q9Y4W6,P11177,Q9H9S5,O96028,Q9BX67,Q9Y3C6,P55795,Q15051,Q9UQE7,P25705,Q8NAT1,P15291,P42356,O60826 38 +Erythroderma 0.3606458085057499 0.3299728372481363 0.7414204864227383 1.0 0.9797292347064052 11 P00813 1 +Preaxial polydactyly 0.3215092525739169 0.3285169204066396 0.7425208529240024 1.0 0.9797292347064052 19 O96028,Q9UHX1 2 +Fine hair 0.3290969071003096 0.3283710753309471 0.7426311101274536 1.0 0.9797292347064052 17 A2RRP1,O75530,Q6PGP7 3 +Overweight 0.3825365867301132 0.3259073923989802 0.7444944224816965 1.0 0.9797292347064052 8 Q01082,P49748 2 +Pollakisuria 0.4619400934322802 0.3257155830993051 0.7446395530387524 1.0 0.9797292347064052 4 Q06787,O60934,P54886 3 +Eeg with polyspike wave complexes 0.3824690608170135 0.3256719516629571 0.744672567587648 1.0 0.9797292347064052 8 P11166,Q14108 2 +Irregular vertebral endplates 0.4392459642607716 0.325254904845198 0.7449881575891688 1.0 0.9797292347064052 5 Q96L58,O15228 2 +Broad thumb 0.3027643043667588 0.3247288716137259 0.7453862814487235 1.0 0.9797292347064052 33 Q9UHX1,Q8N3R9,O75530 3 +Abnormal pulmonary valve morphology 0.3358105719828508 0.3246811911058875 0.7454223714062671 1.0 0.9797292347064052 16 Q9BUB7,O00192 2 +Depressed nasal tip 0.4390170968643865 0.3245831616836845 0.7454965728258767 1.0 0.9797292347064052 5 Q01082 1 +Congenital hepatic fibrosis 0.3816921712916493 0.3229679487678673 0.7467195155573862 1.0 0.980781681400558 8 O15078 1 +Facial asymmetry 0.2983767716918682 0.3208570202394565 0.7483187460455167 1.0 0.9815450424746188 36 A2RRP1,Q9UQE7,Q01105,Q8NCH0,Q9UHX1,Q96JJ3,O15287,O96028,P11274 9 +Coloboma 0.2835337506076818 0.3200247901013338 0.7489495382175964 1.0 0.9815450424746188 57 Q9UHX1,O60826,O15078,Q8WXW3,O43505,Q8NAT1,Q8N201,Q01082,Q9H9S5,O96028,Q9UBM7,Q96EK5,Q5H8A4,O14936 14 +Abnormal inflammatory response 0.3074873601735123 0.3193277373616231 0.7494780014573132 1.0 0.9815450424746188 266 P22830,Q13045,P26038,P14174,Q71SY5,P02545,P06753,Q13126,P39210,O00192,Q9UBM7,Q13432,P16278,P11717,P35579,P10321,Q8NCH0,P49748,P28070,P02786,Q14739,Q9NXR1,P00813,Q6PGP7,Q5H8A4,Q92542,P00403,P03886,P20700,O00754,Q15056,P52732,Q03252,O43707,Q9Y448,P08236,O15484,P51798,P04439,O96028,P78536,Q8N1F7,P31749,Q9UQE7,Q9NZ08,Q9NWH9,Q15437,Q01082,Q9NQH7,Q9NUN5,Q9UIG0 51 +Celiac disease 0.4594668865073031 0.3188367795452849 0.7498502866117589 1.0 0.9815450424746188 4 Q13043,Q9Y5L0,P40763 3 +Lateral clavicle hook 0.4593639795958469 0.3185520768823855 0.7500661986129167 1.0 0.9815450424746188 4 Q9Y619 1 +Hyperammonemia 0.296476574035083 0.3153971727194345 0.7524601132206192 1.0 0.9823677309579728 38 P22695,Q86VD7,P49748,P23786,O43772,P11177,Q9BUB7 7 +Hemianopia 0.357024257414214 0.3152421319972178 0.7525778184227208 1.0 0.9823677309579728 11 P03886,P31749,P00403 3 +Underdeveloped tragus 0.4268058225762039 0.3136611517967895 0.7537784091046922 1.0 0.9833824444439936 2 Q5SRE5 1 +Aplasia hypoplasia of the cerebellar vermis 0.2811334986153909 0.3115910683545235 0.7553513229641688 1.0 0.9846052167782589 80 Q15051,P07942,O60826,P98175,O15078,P23786,Q9Y487,Q9UBM7,Q8WXW3,O43505,Q8NAT1,Q8N201,P15291,Q9H9S5,Q9HC21 15 +Acidemia 0.3460267335693263 0.3106647560449747 0.7560554929409486 1.0 0.98524674024021 14 O14678,Q9NUN5 2 +Varicose veins 0.4112912620597326 0.3094526979730828 0.756977188953236 1.0 0.985342576208876 6 O00192 1 +Venous insufficiency 0.4112912620597326 0.3094526979730828 0.756977188953236 1.0 0.985342576208876 6 O00192 1 +Abnormality of the hallux 0.2819690623366085 0.3071695079712857 0.7587143534273539 1.0 0.9867745872871296 59 P55011,Q9UHX1,Q8WVQ1,Q15056,Q15233,Q96L58,Q93009,Q8N3R9,O96028,O60826,Q5H8A4,P31749,Q9UIG0 13 +Ureteral obstruction 0.3668891712032002 0.3066501538727958 0.7591096742862775 1.0 0.9870124947980784 9 Q9UBM7 1 +Multifocal cerebral white matter abnormalities 0.4101508532646587 0.3059995924011798 0.7596049561191767 1.0 0.9871348018411924 6 Q9Y619,P10253 2 +Motor polyneuropathy 0.3527975144993771 0.3054106167390059 0.7600534368383445 1.0 0.9871348018411924 12 P07196 1 +Epistaxis 0.331698886701552 0.3046102904978131 0.7606629815967008 1.0 0.9873745462234268 16 P35579,P12814,P38435,Q86YV9,P49257,P04062 6 +Hemiplegia hemiparesis 0.2867923125520938 0.3038197882132182 0.7612651901234937 1.0 0.9876677286463522 46 P03886,P11166,O60313,Q15051,O95155,O15078,Q9NZ08,Q7LG56,Q9H9S5,P00403 10 +Adducted thumb 0.3022646327746399 0.3026110137144995 0.762186320067801 1.0 0.9879720583975092 32 Q8NCH0,Q15056,Q96L58,Q71SY5,P42892,Q9UIG0 6 +Broad philtrum 0.3439697065003548 0.3015125566879126 0.7630236764052429 1.0 0.9887816576283224 14 Q12824,P11166,Q96CW1,P51532,Q01082,Q9BZK7,Q8TAQ2 7 +Abnormal nasal mucosa morphology 0.4526474550396043 0.3002360497513907 0.7639971090007902 1.0 0.9889801621553896 4 Q13432 1 +Abnormality of globe size 0.2767984618527115 0.2998966413162163 0.764255996329513 1.0 0.9889801621553896 70 P11166,O60566,Q9UHX1,Q15555,O15078,O75569,O15287,O43505,Q96N67,P52732,Q71SY5,Q8N201,P30533,Q9H9S5,Q8NAT1,O75431,O00192,O14936 18 +Leukodystrophy 0.2799101543610954 0.299358390245945 0.7646666069774726 1.0 0.9889801621553896 64 P03886,P20700,P07602,O43676,O75251,Q01082,O43681,O75380,Q7KZN9,Q96CU9 10 +Oculomotor apraxia 0.3106873776577488 0.29852971050202 0.765298903593393 1.0 0.9894781631044932 28 O15078,Q8WXW3,O96008,Q9NQT5,Q10713,Q9Y4W6,O14773,P11274,P05067 9 +Vocal cord paresis 0.4518232939669656 0.2980250905544548 0.7656840137832361 1.0 0.9894781631044932 4 O95140 1 +Abnormal size of pituitary gland 0.4069672266174287 0.2964506358567915 0.7668859603339377 1.0 0.9900130429440344 6 P35222,Q9NXR1,P31749 3 +Abnormal serum iron concentration 0.45118751280159 0.2963250222922626 0.7669818785603424 1.0 0.9900130429440344 4 Q6PGP7 1 +Broad forehead 0.2894981499474285 0.2960442365567079 0.7671962988048096 1.0 0.9900130429440344 43 Q13045,O00754,Q8NCH0,Q15056,Q9UIG0,Q01082,O75530,O60826,O14936 9 +Abnormality of alkaline phosphatase level 0.3148956881307608 0.2958729772176043 0.7673270886641856 1.0 0.9900130429440344 25 Q13043,Q9Y2V7,P22626,Q96JJ3,Q96A33,Q14739,P51798,Q969N2,P11274,Q9UJS0 10 +Shyness 0.4508522170289174 0.2954303915904165 0.7676651196732802 1.0 0.9900130429440344 4 Q15233 1 +Dilatation of the cerebral artery 0.353032603991787 0.2943553549884227 0.7684863779832058 1.0 0.99061198293702 10 Q01082,P42224,P10253 3 +Increased serum iron 0.4667379980074033 0.2936781742166775 0.7690038337036198 1.0 0.9906253045927615 3 Q6PGP7 1 +Ovarian neoplasm 0.3121606033881027 0.2878339681838684 0.7734738343212175 1.0 0.99395725111158 26 P20585,P51809,Q92878,P31749,P02545,P48735,P35222,Q01844 8 +Vestibular dysfunction 0.3024484474605458 0.28732676138944 0.7738621335316755 1.0 0.99395725111158 31 P41440,Q9NZ08,P06280 3 +Short fourth metatarsal 0.4640109890109908 0.2867231700221058 0.774324295029682 1.0 0.994048106351692 3 Q9NQ48,Q15910 2 +Abnormality of the nasal alae 0.2744467149042943 0.2861716470627225 0.7747466584146889 1.0 0.994048106351692 178 Q13045,O15344,P98175,Q96N67,Q71SY5,Q5KU26,Q9Y366,Q9UBM7,Q16625,P16278,P11166,O60566,Q9UHX1,Q8WVQ1,Q96L58,Q9Y487,Q15392,P15586,O95831,Q13868,Q9BUB7,Q6PGP7,Q969N2,P29372,O14936,O15078,Q8WXW3,P52732,Q9Y448,O75431,P11274,P31749,P55795,Q9UQE7,O15228,Q15555,Q01082,P10586 38 +Left atrial enlargement 0.4635926929210348 0.2856641862215135 0.775135337355445 1.0 0.994048106351692 3 P13807 1 +Abnormal left atrium morphology 0.4635926929210348 0.2856641862215135 0.775135337355445 1.0 0.994048106351692 3 P13807 1 +Neoplasm of the male external genitalia 0.3477969381598986 0.2849899914572348 0.7756518097774197 1.0 0.994048106351692 12 P31749,Q13423,P51809 3 +Anhidrosis 0.4249008225178862 0.2843921096925658 0.7761099050370683 1.0 0.994048106351692 5 P04066 1 +Ectopic kidney 0.3274312125812727 0.2841522387430264 0.7762937153612544 1.0 0.994048106351692 16 Q9BX67,Q9Y448,Q9UHX1,Q15056 4 +Cardiovascular calcification 0.3501300196781269 0.2833442980804068 0.7769129230261496 1.0 0.994048106351692 10 P02545,P42224,O75431,P04062,O75844 5 +Large basal ganglia 0.3130616473195096 0.2832157090235602 0.7770114870751177 1.0 0.994048106351692 19 Q96N66,Q14139,P55011,Q71SY5,Q9UBB6,Q9NUQ7 6 +Aplasia hypoplasia of the phalanges of the thumb 0.3489080305622798 0.2830460364349089 0.7771415473156222 1.0 0.994048106351692 11 Q9Y448,Q8WVQ1 2 +Nasal regurgitation 0.4155451798956253 0.2814207051344184 0.7783877391647014 1.0 0.994474301063562 2 Q9BUF5 1 +Abnormal circulating estrogen level 0.3465429375351208 0.279940855373454 0.7795228817658901 1.0 0.9949032770024968 12 Q8IY37,P57740,P31749,P51809 4 +Hypoplastic nipples 0.3479722986793935 0.2794093920191288 0.7799306642058768 1.0 0.9951504109183716 11 P10586 1 +Abnormality of muscle size 0.2900642657043075 0.2790620004409442 0.7801972443606573 1.0 0.9952172919417992 219 Q99720,P55263,Q8TD16,Q71SY5,P02545,P06753,O75298,Q13126,P10253,P39210,Q9HC21,Q9NR77,P16278,O60313,Q8N0X7,Q9Y487,Q7Z406,Q9BQT8,Q14203,O95831,Q13049,Q6DKK2,O00754,Q15056,O15078,O43505,Q7LG56,Q03252,Q9H9S5,P04066,Q68CQ7,Q15165,Q15437,Q14331,Q8NAT1,Q96RK4,P07196,Q9UIG0 38 +Limited hip movement 0.3192455991772907 0.2785877212325407 0.780561236831433 1.0 0.9954083610196676 17 P02545,O75844,Q8TD16 3 +Abnormal electroretinogram 0.2905720565434193 0.2778569306841953 0.7811221867818592 1.0 0.9958504257819752 39 Q15051,Q15555,O15078,P50897,P00846,O15484,Q13049 7 +Puberty and gonadal disorders 0.2707451519598699 0.2762970069436914 0.7823199545918378 1.0 0.9971039026298052 171 Q13045,Q14108,Q4J6C6,Q8IWS0,P02545,Q8N3R9,Q9UBM7,P06280,O60313,O43395,O95714,Q96RR1,Q969N2,Q13049,P00403,P03886,O14936,P55011,O95155,Q15056,Q15233,O15078,Q7LG56,O95470,O15287,O96028,P04062,P48735,O43172,P31749,Q9UQE7,Q15555,Q8WWY3,Q13423,P51809,Q01082,Q93009,Q16740,Q96RK4,O75844,O75175,P49770,Q9UIG0 43 +Urethrovaginal fistula 0.4133479813238001 0.2753584828228558 0.783040837482766 1.0 0.99747554051053 2 Q8NCM8 1 +Bifid epiglottis 0.4133479813238001 0.2753584828228558 0.783040837482766 1.0 0.99747554051053 2 Q8NCM8 1 +Abnormal circulating iga level 0.3254944409936374 0.2749983782229581 0.7833174842828357 1.0 0.9975544942346772 16 P00813,Q969N2 2 +Poor coordination 0.3466169367125538 0.2741702918734988 0.7839537573220436 1.0 0.9978178883252636 11 Q96L73,Q9Y619,O75530 3 +Poor wound healing 0.3763131204075929 0.2721128474137437 0.785535251345566 1.0 0.9982917851135248 7 P40818,O15269,P04062 3 +Saccadic smooth pursuit 0.4202079061724195 0.2715899966357205 0.7859372919715057 1.0 0.9982917851135248 5 O14773,Q10713 2 +Neoplasm of the endocrine system 0.2835986857495702 0.2687212478475151 0.788144199598356 1.0 0.9983285763598814 45 P02545,P20585,P42892,Q15437 4 +Prominent nasal bridge 0.277478832874371 0.2664682216060677 0.78987863039537 1.0 0.9983285763598814 57 P20700,Q9UQE7,O15078,Q8WXW3,Q8WVM7,Q96N67,P11274,Q9NXR1,P42892,Q96RK4,O00192,Q96EK5,Q13049,O14936 14 +Muscle weakness 0.3150449300137621 0.266270004226924 0.7900312726069734 1.0 0.9983285763598814 313 Q99720,Q4J6C6,Q9HC07,Q7RTS9,Q8TD16,O43772,Q71SY5,P02545,Q5KU26,P06753,Q13126,P10253,P39210,O75298,Q00796,Q9NR77,Q70HW3,Q9UHX1,Q8NCH0,P49748,Q8N0X7,O43676,Q7Z406,Q14203,O95831,O75251,Q14739,Q9BPX6,Q96RR1,Q13049,Q6DKK2,P50336,P03886,P20700,O14936,P07602,P23786,P00846,O43505,Q7LG56,Q96F07,Q9H9S5,P51798,P41440,Q96CU9,Q68CQ7,Q15165,O75306,Q14331,O43681,O75380,Q8NFF5,P07196,Q9GZY8 54 +Abnormal cerebral artery morphology 0.3092724399281426 0.2659713299395856 0.7902612893676557 1.0 0.9983285763598814 18 P10253,P05067 2 +Dysphonia 0.2910544857889559 0.2658791077933674 0.7903323157105797 1.0 0.9983285763598814 34 P20700,Q15056,Q15233,O75569,Q14203,Q96RR1,Q6DKK2,Q9UIG0 8 +Recurrent fractures 0.2908878198275634 0.264771116399772 0.791185788782891 1.0 0.9983285763598814 34 Q96L58,P48735,Q13126,O75718 4 +Facial hypotonia 0.3294794942075767 0.2639172839318614 0.7918436570387097 1.0 0.9983285763598814 15 O00754,P10253,Q8N3U4,Q13555 4 +Abnormally low pitched voice 0.3546561398265008 0.263465409478926 0.7921918812154924 1.0 0.9983285763598814 9 Q9UQE7,Q96L73,Q14683,O75530 4 +Arthropathy 0.3729372937293843 0.2618219126106073 0.7934587443913361 1.0 0.9983285763598814 7 O15269,Q9Y3Z3,P40763,Q6DD88,O95163,Q9UBC1 6 +Thyroid adenoma 0.3948620814080981 0.2614029311040096 0.7937817969055962 1.0 0.9983285763598814 6 P20585 1 +Agammaglobulinemia 0.4533730430909011 0.2604511592023426 0.7945157848160651 1.0 0.998408559232086 3 Q9NRZ9 1 +Reduced forced vital capacity 0.4153043163801606 0.2585229503966864 0.7960033389183778 1.0 1.0 5 P06753,Q9H9S5 2 +Dyspareunia 0.4355592195658316 0.2560881302817919 0.7978827871222272 1.0 1.0 4 Q9P2D1,P01889,O00170 3 +Recurrent ear infections 0.4142431474860412 0.2557374912000126 0.7981535437585925 1.0 1.0 5 Q9Y448 1 +Visual hallucinations 0.3924300187426584 0.2546098407623399 0.7990244578033341 1.0 1.0 6 Q9NWW5 1 +Hypoplasia of penis 0.2741842103691012 0.2539932130161735 0.7995008014365697 1.0 1.0 119 Q8IWS0,O75419,Q9UBM7,Q9Y619,Q9H0U9,O60566,O43395,O95714,Q10713,P42892,P55265,Q13049,Q14839,Q96L73,O14936,O95155,Q15056,O15078,O43505,Q03252,Q9H9S5,O95470,O75530,O43172,Q9UQE7,Q15555,Q8WWY3,P51809,Q8NAT1,Q01082,Q93009,Q96RK4,O60826,Q15042,Q9UIG0 35 +Hip dislocation 0.2733048283622738 0.2537674242101952 0.7996752414836421 1.0 1.0 68 Q9UQE7,P55011,Q9UHX1,Q96L58,Q9Y487,O15287,Q8TD16,Q9NQT5,P02545,P06753,Q9H9S5,O96028,Q9UBM7,O75844,P31749 15 +Congenital diaphragmatic hernia 0.3076991391928314 0.2533994881152617 0.7999595231772498 1.0 1.0 24 O96028,Q9UBM7,Q5H8A4,Q9UQE7 4 +Syringomyelia 0.4130573315252746 0.2526428507342304 0.8005442138170575 1.0 1.0 5 Q9Y2U8 1 +Semilobar holoprosencephaly 0.4337652378211835 0.2516651302339998 0.8012999116728952 1.0 1.0 4 Q8N3U4 1 +Anisopoikilocytosis 0.449175824175826 0.2504700389991416 0.8022238718147465 1.0 1.0 3 O75845,Q05682 2 +Axonal degeneration regeneration 0.4322682792805068 0.2480060591805602 0.8041297186879801 1.0 1.0 4 P02545 1 +Hypogonadotropic hypogonadism 0.2936547101778238 0.2473837945925212 0.8046112145459228 1.0 1.0 32 P03886,Q15056,O95714,Q9UIG0,Q7LG56,P35222,Q15042,Q8IY37,P31749,P00403 10 +Bulbar palsy 0.3380267833472277 0.2464449210727154 0.8053378362835553 1.0 1.0 12 O43681 1 +Limited elbow movement 0.2860005432331634 0.24568344598034 0.8059272876969867 1.0 1.0 39 Q96L58,P23786,Q7RTS9,Q8WVM7,P02545,P06753 6 +Myoglobinuria 0.3390445064484804 0.2455339595357215 0.8060430168468902 1.0 1.0 11 P23786,Q9H9S5 2 +Bone marrow foam cells 0.4468944388559906 0.2451379106406285 0.8063496498052003 1.0 1.0 3 O15118 1 +Bilateral cleft lip 0.4467032967032984 0.2446941642689575 0.8066932469468284 1.0 1.0 3 O15111,Q9NXE4 2 +Cutaneous cyst 0.4467032967032984 0.2446941642689575 0.8066932469468284 1.0 1.0 3 Q9H488,Q8TAA9 2 +Squamous cell carcinoma of the skin 0.4305574346731188 0.2438596245305374 0.8073395402179984 1.0 1.0 4 P02545 1 +Increased proteinogenic amino acid level in urine 0.3354373582152642 0.2429834603061456 0.8080182103110842 1.0 1.0 13 Q9NUN5,Q4J6C6 2 +Decreased cd4 cd8 ratio 0.4299746433871429 0.2424558326005808 0.8084269764295375 1.0 1.0 4 Q13432 1 +Postaxial polydactyly 0.2989282526902676 0.2396238807052851 0.8106218499340019 1.0 1.0 29 P98175,O15078,Q14739,Q96RK4,Q9Y366,Q9UBM7,Q13049 7 +Short foot 0.2868217562779824 0.2380526483487853 0.8118402601946288 1.0 1.0 34 Q9UQE7,O95155,Q9NX62,Q8N0X7,Q13555 5 +Panniculitis 0.3468109023535871 0.2371243188667453 0.8125603465802027 1.0 1.0 9 P28070 1 +Optic disc hypoplasia 0.3859581260131501 0.2369518149050736 0.8126941718946583 1.0 1.0 6 O14802,Q96KP1,Q00839,Q9H3H1 4 +Epileptic encephalopathy 0.3001325938916075 0.2363705187270958 0.8131451707402584 1.0 1.0 28 P11166,Q8WVM7,Q96F07,Q96RR1,Q13813 5 +Recurrent bacterial infections 0.3046818154108672 0.2361864481541042 0.8132879948852367 1.0 1.0 23 P00813,Q9Y448,P78536 3 +Bowel diverticulosis 0.336963235112875 0.2353195794006977 0.8139606995915754 1.0 1.0 10 Q15056,Q9UIG0 2 +Congestive heart failure 0.2713652753938838 0.2352993829672765 0.8139763740008015 1.0 1.0 68 P16278,P03886,Q70HW3,Q15555,Q15056,O75306,P02545,Q01082,P25705,P10253,P09493,Q9BUB7,P06280 13 +Arterial rupture 0.4417582417582437 0.2333762485745056 0.8154692549065672 1.0 1.0 3 Q9NWM8,O60568 2 +Abnormal central sensory function 0.4051375259583562 0.2324684707386658 0.816174173183287 1.0 1.0 5 O75787,P31749 2 +Gonadal dysgenesis 0.3352472920908544 0.2315926732273401 0.8168543987348937 1.0 1.0 11 Q96RR1,P57740,P51809 3 +Dysarthria 0.2667109756856297 0.2298174270715471 0.8182336422971375 1.0 1.0 169 Q14108,O15118,Q9UEY8,O75027,O14773,O75503,Q7KZN9,Q5THJ4,P11166,Q8N0X7,P15586,Q14203,Q10713,O75251,Q9H6K4,Q96RR1,Q6DKK2,P20700,O00754,P07602,Q8IV08,Q15233,Q15056,P00846,Q7LG56,Q9Y4W6,P41440,Q96CU9,P17480,P49792,P61916,O75569,O75306,O43681,P42356,P07196,P49770,Q9UIG0 38 +Decreased fertility in females 0.3613861386138736 0.2279690576318768 0.819670295610476 1.0 1.0 7 P51809,Q96RD7,Q15645,Q8IY37,O00170,P54132 6 +Productive cough 0.3613861386138728 0.2279690576318745 0.8196702956104778 1.0 1.0 7 Q6UN15,P10644,Q14980,P40763,P06748,Q9BZK7 6 +Restrictive ventilatory defect 0.3211730404348604 0.2277470215535093 0.8198429149613138 1.0 1.0 15 P16278,Q96L58,Q9H9S5 3 +Paraparesis 0.2966069354446557 0.2261158731034405 0.8211112993283147 1.0 1.0 29 P31040,Q8N0X7,P35637,O75787,Q9Y4W6,Q9H6K4,P42356,P04062,Q9Y619,Q6DKK2 10 +Spotty hypopigmentation 0.3941224938203754 0.2256335690735176 0.8214864297009905 1.0 1.0 2 Q9NP58 1 +Abnormality of the abdominal wall 0.2645297858279805 0.2244558656485217 0.8224026048903401 1.0 1.0 132 Q71SY5,P02545,O00192,Q9UBM7,P16278,Q9UHX1,Q8NCH0,Q8WVQ1,Q9Y487,Q96JJ3,Q14739,O14678,Q9BUB7,O14936,O00754,Q15056,Q9Y448,O75530,P11274,Q15555,P04066,Q96HY6,O60826,O75844 24 +Abnormality of vitamin metabolism 0.2962612384865029 0.2241195564969615 0.8226642756275151 1.0 1.0 29 O14678,Q01082,P41440,Q9NUN5 4 +Abnormal thorax morphology 0.295436075467854 0.2239577278696785 0.8227901960209003 1.0 1.0 246 P98175,Q7RTS9,Q8TD16,O75419,Q71SY5,Q8N201,P02545,P06753,Q8N3R9,P54802,Q9Y366,Q9UBM7,O00192,P16278,P11166,O60313,Q9UHX1,Q8NCH0,Q8WVQ1,Q96L58,Q9Y487,Q96JJ3,P15586,O75718,O95831,Q14739,Q6ZXV5,P00813,Q969N2,O00754,P55011,O95155,Q15056,P08236,O75431,P51798,O96028,Q9UQE7,Q15555,P04066,Q9NWH9,P46783,Q15437,Q14331,Q96HY6,O60826,O75844,P07196,Q9UIG0 49 +Abnormal circulating follicle stimulating hormone concentration 0.3598131174925596 0.2235264512753327 0.8231257987186551 1.0 1.0 7 Q8IY37,P31749,P51809 3 +Abnormal odontoid tissue morphology 0.270657963803614 0.223019048292275 0.823520681436126 1.0 1.0 50 P16278,Q9Y366,Q15056,Q96L58,Q9HC07,Q96JJ3,Q6P4Q7,O00192,Q9UBM7 9 +Oligomenorrhea 0.3590359853669577 0.2213467753334042 0.8248224316374109 1.0 1.0 7 P31751 1 +Spinal canal stenosis 0.3501781656124619 0.2212269762505884 0.8249157055756369 1.0 1.0 8 O95155,P31749 2 +Bimanual synkinesia 0.4354395604395623 0.2193741074129019 0.826358638085404 1.0 1.0 3 P19022,Q9P2D1 2 +Abnormal libido 0.4354395604395622 0.2193741074129016 0.8263586380854042 1.0 1.0 3 Q9P2D1,O00170 2 +Emotional lability 0.2717836164621489 0.2172037378711437 0.8280495718205398 1.0 1.0 59 P07602,Q68CQ7,Q8N0X7,Q15165,Q14203,O75251,Q01082,O43681,Q7KZN9,Q96CU9 10 +Leukocytosis 0.2993379350868403 0.2160610412510435 0.8289401670209671 1.0 1.0 26 P00813,P11274,Q03252 3 +Aplasia hypoplasia of the ribs 0.3000070526830247 0.2137921694039983 0.8307091316926767 1.0 1.0 25 Q9UHX1,O95155,Q96L58,Q96HY6,O60826 5 +Poor appetite 0.3054463365900106 0.2127223367686057 0.8315435432657616 1.0 1.0 17 P11274,Q70HW3,P06753 3 +Exercise induced myoglobinuria 0.3764982845927376 0.2122665522816714 0.8318990882488826 1.0 1.0 6 Q9H9S5 1 +Abnormal joint morphology 0.3095363735539455 0.2111813593683411 0.8327457558154558 1.0 1.0 303 Q14108,Q9HD42,Q7RTS9,Q8IZA0,Q8TD16,Q8WVM7,P14174,Q71SY5,P02545,P06753,O75298,Q9Y366,Q9UBM7,O00192,P06280,Q9NR77,P16278,Q9UHX1,Q8NCH0,Q8WVQ1,Q8N0X7,Q96L58,Q9Y487,P28070,Q7Z406,Q15392,O75787,O95831,O75718,Q14739,Q6ZXV5,P42892,Q9BUB7,Q969N2,O00754,P55011,O95155,P07602,Q15056,P23786,Q03252,Q9Y448,Q9H9S5,P08236,O75431,P51798,O75530,O96028,P11274,Q9UQE7,Q9NX62,Q9NZ08,Q01082,Q96HY6,Q9NUQ7,O75844,P07196,Q9UIG0 58 +Recurrent herpes 0.4163866700066643 0.2109967770540228 0.8328897862834794 1.0 1.0 4 Q13432 1 +Limb fasciculations 0.4313607635469878 0.2106130197286727 0.8331892519204982 1.0 1.0 3 Q92734 1 +Abnormal connection of the cardiac segments 0.2707524305647931 0.2084607600434041 0.8348692185256323 1.0 1.0 58 Q9UHX1,Q15056,P98175,O95155,O60826,O15287,Q8N3U4,P02545,O00192,Q6PGP7,O75844,Q9UIG0 12 +Abnormal aortic arch morphology 0.3276706107696633 0.2076774027810832 0.8354808629558064 1.0 1.0 12 O00192,Q9UHX1 2 +Nasogastric tube feeding 0.293303427828136 0.2072050583049298 0.8358497170835626 1.0 1.0 29 Q96N66,Q14139,P55011,Q15233,Q71SY5,Q9UBB6,Q9Y448,Q9NUQ7,Q9GZY8 9 +Gastric ulcer 0.4292433915461834 0.2061516560715901 0.8366724495351325 1.0 1.0 3 P04062 1 +Cerebral cortical atrophy 0.272640732510397 0.2056634169275146 0.8370538366909552 1.0 1.0 112 O96008,Q8TD16,Q96N67,Q5KU26,Q8N3R9,O75503,P05067,Q16625,Q9NXR1,Q9BUB7,Q96RR1,O14936,P03886,O00754,P00403,P55011,O95155,Q15056,P00846,Q9H9S5,Q9NWS8,Q9UQE7,Q9UIG0 23 +Renal cell carcinoma 0.2983453838701123 0.2033400556289173 0.8388692495719803 1.0 1.0 23 O60566,Q9NWH9,P35222,Q15437,P02545,P31749 6 +Abnormality of the epiphyses of the distal phalanx of finger 0.3839604504257022 0.2018349856151435 0.8400457297996542 1.0 1.0 2 P82673 1 +Atresia of the external auditory canal 0.3141941386860961 0.198602496022242 0.8425737009634293 1.0 1.0 15 Q9UQE7,Q9H9S5,O75419 3 +Smooth philtrum 0.2673089577052464 0.1977725667318836 0.8432230107785135 1.0 1.0 74 Q9UQE7,P55011,Q9UHX1,O15344,Q8WVQ1,Q9Y487,Q01082,Q8N3R9,P10586,P11274,P29372,O14936 12 +Dystrophic fingernails 0.3418977537042984 0.1972836315198669 0.8436055877833142 1.0 1.0 8 O75844 1 +Convex nasal ridge 0.2967144905573017 0.1965566868252275 0.8441744682027565 1.0 1.0 21 O96028,O75844 2 +Neurofibromas 0.3700740402533696 0.1962869104236302 0.8443856060778665 1.0 1.0 6 Q01082,P31749 2 +Focal onset seizure 0.2725897047774462 0.1951721303039723 0.8452581962844217 1.0 1.0 90 Q05639,Q01105,Q96N67,Q71SY5,O75503,P11166,Q9UBX3,P22466,Q6ZXV5,Q96L73,P03886,P00403,O14936,P55011,P07602,Q9UBB6,Q9Y3C6,P31749,Q96N66,Q14139,Q6PJT7,Q01082,P42356,Q9NUQ7 24 +Progressive inability to walk 0.296563682531978 0.194658277928103 0.8456604764141653 1.0 1.0 24 Q96RR1,Q9H9S5,P00846 3 +Abnormal patella morphology 0.2871585415948944 0.1941528135709538 0.8460562290681235 1.0 1.0 31 Q15056,Q8WVQ1,Q9NX62,Q6ZXV5,O00192,Q9UIG0 6 +Visual field defect 0.2673925676142096 0.1938470157141579 0.8462956719609533 1.0 1.0 51 P03886,O60313,O43395,Q15555,Q8WWY3,P54277,P00846,P35222,O75306,Q9H6K4,Q8NHS3,P04439,Q9H061,P31749,P00403 15 +Abnormality of the pulmonary vasculature 0.2724003336443403 0.1938051313492293 0.8463284689587012 1.0 1.0 46 P55011,Q15056,Q15392,O75718,P02545,Q8N3R9,P51798,Q6PGP7,O75175,Q9UIG0 10 +Abnormal circulating proline concentration 0.408154312135513 0.1931482387286755 0.846842874827725 1.0 1.0 4 P20674,Q9P0J1 2 +Lipid accumulation in hepatocytes 0.2667561723531094 0.1924424232023241 0.8473956644596852 1.0 1.0 74 P55263,O95155,P49748,P23786,O43772,O75787,Q7LG56,P02545,Q03252,Q01082,P31751,P39210,O75431,Q7KZN9 14 +Abnormality of retinal pigmentation 0.2718196773751599 0.1915051520701777 0.848129844471949 1.0 1.0 88 P02545,Q7KZN9,Q13432,Q96JJ3,O75251,Q6P4Q7,Q8NHS3,Q13049,P00403,P03886,O15078,P00846,Q7LG56,P52732,Q9H9S5,Q96CU9,P31749,Q15051,Q15555,O75306,Q96RK4 21 +Abnormal heart valve physiology 0.2727995251006773 0.1902613060518866 0.8491043730728254 1.0 1.0 95 P55263,P02545,P06280,P16278,O60566,Q9UHX1,Q96L58,Q6ZXV5,P00813,Q6PGP7,O00754,Q15056,O75431,P09493,P11274,Q9UQE7,Q9NZ08,O75306,Q01082,O60826,O75844,Q9UIG0 22 +Embryonal renal neoplasm 0.3214681303179689 0.1895607206274375 0.8496533694471329 1.0 1.0 13 Q96L73,O60566,P51809 3 +Nephritis 0.295328860593556 0.1881350573807928 0.8507707799359192 1.0 1.0 23 P35579,Q03252,O43707 3 +Respiratory insufficiency 0.2752309731459867 0.1879872056528875 0.850886680786008 1.0 1.0 196 Q7RTS9,Q8TD16,O43772,P02545,P06753,P10253,P06280,Q9NR77,Q70HW3,Q8WVQ1,P49748,Q96L58,O43676,Q14203,O95831,O75251,Q14739,Q96RR1,P03886,P07602,P23786,Q9Y448,Q9H9S5,Q96CU9,Q68CQ7,P61916,Q15165,O75380,Q8NFF5 29 +Aspiration 0.322247013836099 0.1856523388158819 0.8527174065395329 1.0 1.0 10 O15344,Q9H2P0,P43243,P42356,P29372 5 +Delirium 0.3765449052458044 0.1855829437455821 0.8527718301200118 1.0 1.0 2 Q9UJS0 1 +Gingival bleeding 0.3201206309325056 0.184637227621982 0.8535135845138122 1.0 1.0 13 Q14108,Q96JJ3,Q02241,P49257,P04062 5 +Increased susceptibility to fractures 0.267729154675724 0.1838869456474185 0.8541021460398 1.0 1.0 57 Q14108,Q96L58,O75718,Q14739,P06753,Q13126,P39210,P48735 8 +Difficulty climbing stairs 0.2920865645652388 0.1819777622915424 0.8556001776189661 1.0 1.0 18 Q96RR1,P06753,Q9H9S5 3 +Facial shape deformation 0.4027058075226689 0.1818489742770324 0.8557012493187872 1.0 1.0 4 O75431 1 +Disinhibition 0.2675758286443944 0.1815596792000892 0.855928294176155 1.0 1.0 59 Q05639,Q96N66,Q14139,P55011,P17480,Q15233,O96008,Q6PJT7,Q9NUQ7,Q14203,Q71SY5,Q9UBB6,Q96F07,Q93009,Q01082,P04062,P23378,P05067 18 +Hepatoblastoma 0.3207906987665934 0.1809816640008794 0.8563819683539047 1.0 1.0 10 Q12824,P51532,Q8TAQ2,Q6PGP7 4 +Alkalosis 0.3829026937877837 0.1805951587784751 0.8566853561360968 1.0 1.0 5 P01889,Q9Y619,P40818,O00170 4 +Abnormal location of ears 0.2981489170629025 0.1801303628224462 0.8570502263751572 1.0 1.0 265 P98175,Q4J6C6,Q9HC07,Q8WVM7,O75419,Q71SY5,Q8N201,P02545,P06753,Q9Y366,Q9UBM7,O00192,Q96EK5,Q16625,P16278,O60566,Q9UHX1,Q8WVQ1,Q8NCH0,Q8N0X7,Q96L58,Q9Y487,Q15392,O75787,O95831,P15586,Q13868,Q14739,P42892,Q9BUB7,Q6PGP7,Q969N2,Q13049,Q9Y3D3,P55011,O95155,Q15056,O15078,P23786,Q8WXW3,O43505,Q9H9S5,O75530,O96028,Q9UQE7,Q15555,Q13555,P46783,Q8NAT1,Q93009,Q96RK4,O60826,O75844,Q9NUN5,Q9UIG0 55 +Chronic kidney disease 0.2766996943517441 0.1798503546180748 0.8572700508274373 1.0 1.0 38 Q15051,O15078,P23786,O43707,Q8N1F7,P50336 6 +Spastic tetraplegia 0.2702846395786877 0.1784315142809855 0.8583841015839984 1.0 1.0 46 P16278,Q86XL3,P04066,Q15046,Q01082,Q9NXR1,O43681,Q13813,Q9Y3C6,Q9UEY8,P49792 11 +Abnormal cerebellar vermis morphology 0.2702097156727231 0.177604364054934 0.8590336970159711 1.0 1.0 87 Q15051,P07942,O60826,P98175,O15078,P23786,Q9Y487,Q9UBM7,Q8WXW3,O43505,Q8NAT1,Q8N201,P15291,Q9H9S5,Q9HC21 15 +Increased hepatic glycogen content 0.4005749199513101 0.1775422843431994 0.8590824546478659 1.0 1.0 4 P31040,P31751 2 +Pancreatic cysts 0.3422132615881463 0.1766833478904608 0.8597571215453264 1.0 1.0 7 O15078 1 +Spontaneous hematomas 0.414010989010991 0.1758253225246706 0.860431175045721 1.0 1.0 3 P17301,Q6YHK3 2 +Male infertility 0.3612867748144155 0.175485337256931 0.8606982911821484 1.0 1.0 6 Q02750,P51809,Q8IY37,Q06124,P54132 5 +Long fingers 0.2684582652463549 0.1753541744926425 0.860801346058734 1.0 1.0 82 Q15555,Q9UHX1,O00192,P23786,Q96L58,Q03252,Q96EK5,P42892,O75530,O96028,P11274 11 +Widely spaced incisors 0.3804252026608405 0.1752645354126958 0.8608717770474597 1.0 1.0 5 Q8WVM7 1 +Uterus didelphys 0.4134615384615404 0.1747899614421392 0.8612446765178345 1.0 1.0 3 Q8NCM8,O14974 2 +Horizontal ribs 0.4134615384615403 0.1747899614421389 0.8612446765178348 1.0 1.0 3 Q8NCM8,O75147 2 +Primary gonadal insufficiency 0.3336292335268791 0.1746281798928617 0.8613718044577909 1.0 1.0 8 Q8IY37,P49770,P51809 3 +Abnormality of hindbrain morphology 0.3069625535575886 0.1745290828402324 0.8614496766948427 1.0 1.0 302 Q99720,P07942,Q14108,P98175,Q9HD42,Q9UIG0,Q8TD16,Q96N67,O75419,Q8N201,O14773,O75503,Q9HC21,Q9UBM7,Q16625,O60313,O60566,Q8N0X7,Q9Y487,P80404,O75787,Q13868,Q8NHS3,Q9NXR1,Q9H6K4,Q96RR1,Q969N2,Q5H8A4,Q13813,Q6DKK2,O14936,P20700,O00754,Q15056,Q8IV08,Q15233,O15078,P23786,Q8WXW3,P00846,O43505,Q7LG56,Q9Y4W6,Q96F07,P11177,Q9H9S5,P51798,O96028,Q9BX67,P41440,Q96CU9,P17480,P31749,Q9Y3C6,P55795,Q15051,Q9UQE7,Q9NQT5,Q15437,P25705,Q8NAT1,P15291,O60826,Q9GZY8 64 +Abnormality of skin pigmentation 0.2529942978604219 0.1740380960027959 0.8618355227899492 1.0 1.0 142 Q8IZA0,P02545,Q8N3R9,O00192,O60566,O95714,P16615,Q14739,Q6PGP7,P50336,Q96L73,P03886,P00403,P55011,P07602,Q9Y2U8,Q9Y448,O75431,P51798,O75530,O15287,P04062,P31749,Q15555,Q13423,Q15437,Q86YV9,Q01082,O75844,O75175 30 +Gait disturbance 0.3155120713601381 0.1736975397392824 0.8621031711376568 1.0 1.0 352 Q13045,Q99720,Q7RTS9,Q8N201,O75503,Q9HC21,P05067,Q9NR77,O60313,Q9BQT8,O95831,Q9H6K4,Q5H8A4,P00403,P03886,P07602,Q8IV08,Q15046,P00846,Q9Y4W6,O75530,P41440,Q96CU9,P17480,P31749,P49792,P55795,Q5TAQ9,O43681,O75175,P07196,P49770,Q05639,Q9GZY8,P98175,Q4J6C6,Q8N3U4,Q71SY5,Q8N3R9,Q9P0J1,Q9Y619,Q00796,P16278,Q5THJ4,O00400,O95714,Q10713,Q13049,Q03252,Q9NZ08,O75844,Q14108,O15118,Q8TD16,P02545,P39210,P11166,O75787,Q9BPX6,Q96RR1,P20700,O95155,Q96F07,Q9H9S5,Q96N66,O75569,Q01082,Q96N67,P06753,O75298,O14773,Q8WVQ1,Q8N0X7,Q14203,O14936,O00754,P55011,Q15056,Q8WXW3,Q7LG56,Q93009,Q9NUQ7,Q9UIG0 83 +Restlessness 0.2746254681472907 0.1727674637994944 0.8628342125436261 1.0 1.0 40 Q68CQ7,Q15165,P52732,Q01082,P42892,P05067 6 +Rotary nystagmus 0.3979872898281424 0.1723979150261809 0.8631247112082063 1.0 1.0 4 Q14738 1 +Communicating hydrocephalus 0.379000765270221 0.172241304712842 0.863247826624792 1.0 1.0 5 P11166 1 +Hyperacusis 0.3256273320839994 0.1717486414216326 0.8636351436187484 1.0 1.0 9 Q15056,Q9UIG0 2 +Abnormality of the diencephalon 0.2744635808355749 0.1717032475683368 0.8636708325450553 1.0 1.0 40 P11166,Q15056,Q9UPT5,P31749,Q96KP1,Q8N3U4,P35222,P49792,O75306,Q9H9S5,Q9NXR1,P19022,Q96RR1,O00443,Q9GZY8,Q14683,Q9UIG0 17 +Hyperaldosteronism 0.369404009887385 0.1708312487607428 0.8643564572755331 1.0 1.0 2 P04637 1 +Abnormality of the liver 0.3132806216984208 0.1694611435865627 0.8654339332160235 1.0 1.0 338 P22830,P55263,Q14108,O15118,Q9HC07,O43772,P14174,Q71SY5,P02545,P10253,P39210,P54802,O00192,Q9UBM7,Q7KZN9,P16278,P11717,P11166,P49748,P28070,O43676,O75787,P15586,O75251,Q14739,P00813,Q96RR1,Q9BUB7,P10619,Q13049,P50336,O14936,P03886,O00754,O95155,P07602,O15078,Q15056,P23786,P00846,Q7LG56,Q03252,P08236,O75431,P51798,O96028,Q9BX67,Q96CU9,Q9NWS8,Q15051,Q96RK4,P04066,P61916,Q9NWH9,O75306,Q15437,Q01082,P31751,O43681,Q96HY6,O75380,Q9NUN5 62 +Renal tubular dysfunction 0.2637527837778856 0.1691853763744424 0.8656508319403817 1.0 1.0 50 P03886,O43676,Q7LG56,O75306,O75251,Q9BRT2,O75380,Q96CU9,Q9NWS8 9 +Embryonal neoplasm 0.2902401917461768 0.1682676985294827 0.8663726843424011 1.0 1.0 26 Q12824,P20585,O60566,P51809,P51532,Q8IY37,Q8TAQ2,Q6PGP7,Q96L73 9 +Increased vertebral height 0.3940126245192032 0.1646792417489819 0.8691964565729617 1.0 1.0 4 O00754 1 +Recurrent skin infections 0.2881901466662946 0.1641257710858469 0.8696321345088154 1.0 1.0 18 P78536,Q9Y448,Q8NCH0 3 +Broad finger 0.272624105197006 0.163624612207012 0.8700266680947801 1.0 1.0 41 Q9UHX1,Q96L58,Q13868,Q9Y448,Q8N3R9,O75530,O14936 7 +Plagiocephaly 0.2743793689063425 0.1629272229121604 0.8705757364262183 1.0 1.0 37 Q9UQE7,Q01105,Q15233,O95714,Q96L58,Q10713,Q96F07,Q93009,Q01082,Q14738,P55265,O75175,O14936 13 +Acute encephalopathy 0.3555198290219783 0.1625093900059612 0.8709047344102934 1.0 1.0 6 Q9Y6N5,P49792 2 +Hyperkalemia 0.3551199554941753 0.1616297369665438 0.8715974384941632 1.0 1.0 6 P11166 1 +Encephalopathy 0.2672355568724158 0.1605314798366034 0.87246242585245 1.0 1.0 117 P03886,P11166,Q9Y6N5,P07602,P23786,O43676,O43772,Q8WVM7,O75251,P25705,Q96F07,Q96N67,Q5KU26,Q13813,O75380,Q96RR1,Q7KZN9,Q96CU9 18 +Facial erythema 0.4054945054945075 0.1602390359255225 0.8726927804429854 1.0 1.0 3 P40818,O00170 2 +Macular degeneration 0.3127586884365001 0.158488316726033 0.8740720262137975 1.0 1.0 13 Q8WWY3,P04439,P50897 3 +Anosmia 0.3721825178669667 0.1581936561971153 0.8743042024342187 1.0 1.0 5 Q8WWQ0,Q9P2D1,Q9NQ48,O95140 4 +Abnormal hypothalamus physiology 0.3271198517263043 0.1577001207801004 0.8746931053159026 1.0 1.0 8 Q14683,Q8N3U4,P31749 3 +Colitis 0.3135407535120941 0.1576802230181968 0.8747087852656563 1.0 1.0 11 Q13043,P42224,P49748,Q6PGP7 4 +Peripheral neuropathy 0.2677591476088988 0.1572012557422261 0.8750862386676013 1.0 1.0 183 P39210,P54802,Q7KZN9,Q9NR77,Q7Z406,O95831,O75251,Q9BPX6,Q96RR1,P03886,P07602,Q8IV08,P00846,P41440,Q9Y2R0,Q96CU9,P04066,O43681,P07196,Q9GZY8 20 +Increased blood pressure 0.2672777299912605 0.1570627949452858 0.8751953589345924 1.0 1.0 84 P03886,Q15051,Q15056,O15078,Q9BUB7,O43707,P02545,P42892,Q96RK4,O00192,Q9NQH7,O75844,Q13049,P06280,P50336 15 +Abnormality of upper limb metaphysis 0.4035714285714304 0.1568564492442687 0.8753579833605007 1.0 1.0 3 Q15910,Q9H1A4 2 +Abnormality of the 1st metacarpal 0.3201471319888461 0.1562839795195404 0.8758091836624866 1.0 1.0 9 Q9UQE7,Q8WVQ1 2 +Patellar subluxation 0.3617138148860152 0.1559349387776978 0.8760843049965066 1.0 1.0 2 P25490 1 +Dermatological manifestations of systemic disorders 0.2652777241486684 0.1558284631374896 0.8761682343422748 1.0 1.0 79 A2RRP1,P11166,P04066,P98175,O15118,P61916,P49748,O43772,Q15437,O75787,P02545,Q01082,Q14739,P39210,O75844,Q16625,O14936 17 +Abnormal cardiac atrium morphology 0.2583805447437829 0.1551730614745693 0.8766848848574849 1.0 1.0 162 P55263,P98175,O75419,Q71SY5,P02545,O00192,Q9UBM7,P13807,O60566,Q8NCH0,P49748,Q96L58,O14678,P42892,Q6PGP7,Q969N2,Q5H8A4,P22695,P20700,Q15056,Q15233,O15078,P52732,O75431,O15287,O96028,P11274,Q9UQE7,P46783,O60826,O75844,Q9UIG0 32 +Interrupted aortic arch 0.3887876729349059 0.154871609376498 0.8769225359989685 1.0 1.0 4 Q8WYQ5 1 +Tall stature 0.2640457805233521 0.1543240827187175 0.8773542095089923 1.0 1.0 63 O00754,P55011,Q8NCH0,Q15233,Q13423,P80404,P06753,Q8N3R9,O75530,O96028,Q5H8A4,Q13049,O75175,P31749,Q96L73 15 +Progressive spasticity 0.2977992564553465 0.1540553740485333 0.8775660744901623 1.0 1.0 16 P07602 1 +Cleft upper lip 0.2732449013557261 0.1537564672213001 0.877801759695219 1.0 1.0 35 Q13045,O15344,Q96L58,Q9H9S5,O96028,Q5H8A4,P29372 7 +Dyspnea 0.2690008381271209 0.1527941993563583 0.8785605722652352 1.0 1.0 107 P03886,Q9UHX1,P07602,Q68CQ7,P23786,Q96L58,P00846,Q15165,O95831,P02545,P10253,Q9Y366,Q96RR1,O75844,P06280 15 +Infertility 0.3104683195592339 0.1506174606838149 0.880277486894687 1.0 1.0 13 Q02750,Q9H7N4,P51809,O95714,Q8WWQ0,P40818,Q96RD7,Q15645,Q8IY37,Q86Y56,Q06124,P54132 12 +Absent distal phalanges 0.3586926668497625 0.1503637633283268 0.8804776288668155 1.0 1.0 2 O15111 1 +Apnea 0.2688416610223549 0.1501633484749048 0.8806357416447721 1.0 1.0 94 P98175,P51114,O43772,Q8N3U4,Q7KZN9,P11166,O60313,O60566,O95714,Q14203,Q10713,O75251,Q969N2,Q96KP1,P03886,P07602,Q15233,O15078,P23786,Q8WXW3,P00846,P51798,P04062,Q96CU9,O75306,P25705,Q93009,P42356 28 +Cortical dysplasia 0.2750286427316729 0.1496588923951249 0.8810337419388015 1.0 1.0 33 Q96N66,Q14139,P55011,O43505,Q71SY5,Q9UBB6,Q9NUQ7 7 +Hypoplasia of teeth 0.2863401192407534 0.1495358973720126 0.881130785780097 1.0 1.0 20 P02545,O75844,O75431 3 +Joint dislocation 0.2691661637721088 0.149464466594328 0.8811871459291347 1.0 1.0 100 Q8TD16,Q8N3U4,O75419,P02545,P06753,O00192,Q9UBM7,Q9UHX1,Q8NCH0,Q8WVQ1,Q96L58,Q9Y487,Q6ZXV5,P55011,Q15056,Q9H9S5,P51798,O15287,O96028,P31749,Q9UQE7,Q9NX62,Q9NQT5,O75844,Q9UIG0 25 +Aspiration pneumonia 0.2841678233743394 0.1492686355098709 0.8813416632093547 1.0 1.0 28 Q12824,P16278,P20700,Q4G0N4,P51532,Q8N3U4,P06753,Q9Y448,Q92734,Q8TAQ2,P04062,Q14683 12 +Gonosomal inheritance 0.2610184162447356 0.1484230572865553 0.882008904513963 1.0 1.0 72 P55795,P26038,O15344,P98175,Q15233,O14936,Q8IWS0,O75787,O95831,O75027,O60826,O95239,P06280,P29372 14 +Ovotestis 0.3575940675638517 0.1483771063973171 0.8820451665210354 1.0 1.0 2 P53701 1 +Glioma 0.3055706263237377 0.1472506986140675 0.8829341449901322 1.0 1.0 14 P20585,P48735,Q96L73 3 +Neoplasm of the small intestine 0.3293286514802587 0.1458505780200643 0.8840393472890073 1.0 1.0 7 P02545 1 +Paraplegia 0.2629851036847547 0.1453435771064981 0.8844396104318293 1.0 1.0 63 P11166,P07942,O00754,Q8N0X7,Q96L58,P00846,O75306,O95831,O75251,O75298,Q7KZN9,Q96CU9 12 +Abnormal circulating sex hormone concentration 0.2861329061981597 0.14465021640656 0.8849870471829901 1.0 1.0 22 Q13423,P51809,P49770,P57740,Q8IY37,P31749 6 +Respiratory failure 0.2604710413695312 0.1437218917157114 0.8857200835811452 1.0 1.0 70 Q70HW3,P07602,Q68CQ7,P61916,P23786,Q8TD16,O75306,Q14203,Q15165,P06753,Q9H9S5,P10253,Q9BUB7 13 +Dyscalculia 0.3089893767261799 0.1435050179147085 0.8858913485453261 1.0 1.0 11 Q06787,Q96L73,P35637,P22626 4 +Abnormality of the ulna 0.2703608275303035 0.1421837025882972 0.8869349044500368 1.0 1.0 39 Q9UQE7,Q15056,Q8WVQ1,Q96L58,O96028,Q969N2,Q9UIG0 7 +Upper extremity joint dislocation 0.2852072654625646 0.1420997960216808 0.8870011792932326 1.0 1.0 21 Q9UQE7,Q8WVQ1,Q96L58,O75419,Q6ZXV5 5 +Central sleep apnea 0.3275874553887039 0.141915007406116 0.8871471401013491 1.0 1.0 7 Q969N2 1 +Abnormal thumb morphology 0.2606345474535824 0.1416134090132331 0.8873853748212523 1.0 1.0 128 Q86XL3,Q71SY5,Q8N3R9,Q9UBM7,Q9UHX1,Q8NCH0,Q8WVQ1,Q8N0X7,Q96L58,Q13868,Q9H6K4,P42892,Q5H8A4,P55011,Q15056,Q15233,O15078,Q03252,Q9Y448,O75530,O96028,Q9UQE7,P46783,Q9UIG0 24 +Depressed nasal ridge 0.2856947499179478 0.141407400689441 0.887548108114508 1.0 1.0 25 P16278,O00754,O60566,O95155,O15078,Q6PGP7,O75175 7 +Decreased pulmonary function 0.3635285827471974 0.1413803273125277 0.8875694946892836 1.0 1.0 5 P08236,P31749 2 +Retinal degeneration 0.2617847608054057 0.1408911831035006 0.8879559075320929 1.0 1.0 66 Q05639,P02545,O14773,Q8N3R9,O75503,O60313,Q10713,O00754,P55011,P50897,Q96F07,Q9H9S5,P04439,P04062,Q9NWW5,O43172,Q8WWY3,Q96RK4,O75175 19 +Decreased proportion of cd4 positive helper t cells 0.320025341838199 0.140181715052241 0.8885164185197796 1.0 1.0 8 Q9Y448 1 +Breast hypoplasia 0.3620120945574588 0.138551731471925 0.889804388008306 1.0 1.0 5 Q8WWQ0,Q9P2D1,P25490,Q9Y619 4 +Abnormal ureter morphology 0.2790213015349126 0.1382481007820926 0.8900443411117693 1.0 1.0 30 O15078,P23786,O75844,P02545,Q969N2,O14936 6 +Abnormal morphology of the limbic system 0.3065085254529493 0.1359807520265837 0.8918364972724797 1.0 1.0 11 Q05639,Q01105,Q96JM3,Q00610,Q9NXR1 5 +Abnormal vertebral segmentation and fusion 0.3504531722054337 0.1359720346544586 0.891843388723689 1.0 1.0 2 Q8TAA9 1 +Hallux valgus 0.2841542980500851 0.1355606882788017 0.8921685847019767 1.0 1.0 22 Q15056,Q15233,Q96L58,Q93009,P04062,P31749,Q9UIG0 7 +Abnormal foveal morphology 0.3775924893045068 0.1351597510552603 0.8924855690227989 1.0 1.0 4 Q86YV9 1 +Abnormal respiratory system morphology 0.3104353463322679 0.1344646723775913 0.8930351447117284 1.0 1.0 334 Q13045,Q14108,O15344,P98175,P26038,Q7RTS9,Q8IZA0,P14174,Q71SY5,P02545,P06753,O75419,P10253,Q8N3R9,P54802,O00192,Q9UBM7,Q92888,P06280,P16278,Q13432,O60566,Q9UHX1,Q8NCH0,P49748,Q96L58,Q9Y487,P28070,P02786,Q15392,O75718,P15586,Q14203,Q14739,Q9NXR1,P00813,Q6PGP7,Q969N2,P29372,P20700,O00754,P55011,P07602,Q15056,P52732,O43707,Q9Y448,P08236,P51798,Q8N1F7,O96028,P11274,P04066,Q68CQ7,Q9NZ08,Q15165,Q86YV9,P25705,Q01082,Q96HY6,O60826,O75844,Q9UIG0 63 +Abnormal facial expression 0.2685278546927951 0.1335435437573554 0.893763529702186 1.0 1.0 40 Q9NR77,O75787,Q14203,Q7LG56,P06753,Q9Y448,Q9H9S5,Q96RR1,Q13049 9 +Abnormal macroscopic urine appearance 0.2816568809079131 0.1316880487482971 0.8952310389044713 1.0 1.0 19 P23786,O43707 2 +Constipation 0.2674188106868579 0.1316196825976755 0.8952851165073441 1.0 1.0 103 Q71SY5,O00192,Q9UBM7,Q8NCH0,Q8N0X7,P42892,Q96RR1,P50336,P03886,P20700,P55011,O95155,Q15056,Q7LG56,Q03252,Q13423,Q01082,Q93009,Q9UIG0 19 +Decreased circulating androgen concentration 0.3041126078636101 0.1288513260478983 0.8974752916861444 1.0 1.0 11 Q8IY37,P31749,P51809 3 +Asymmetric growth 0.304211167223233 0.1286393309744906 0.8976430432337483 1.0 1.0 12 P31751,Q15555,O95155 3 +Neuropathic arthropathy 0.3726298433635843 0.1269905202681032 0.8989479015335362 1.0 1.0 4 O15269,Q6DD88,O95163 3 +Distal sensory loss of all modalities 0.3726298433635802 0.1269905202680968 0.8989479015335413 1.0 1.0 4 P48643,P19367,O15269 3 +Abnormality of mouth size 0.2563419814730656 0.1261448670900882 0.8996172523071371 1.0 1.0 133 Q01105,Q8WVM7,O75419,P02545,Q8N3R9,O00192,Q9UBM7,P16278,P11166,Q8NCH0,Q8WVQ1,Q9Y487,Q15392,P15586,Q9BUB7,Q6PGP7,P55011,O95155,Q15046,Q15233,Q15056,O75431,P11274,P31749,Q15555,Q9NX62,O75844,Q9UIG0 28 +Abnormal internal genitalia 0.2563264107411749 0.1259451169094013 0.8997753688643484 1.0 1.0 133 Q92878,Q9UIG0,P02545,O00192,Q9UBM7,Q9Y6D9,O60566,Q96RR1,Q13049,P20585,Q15056,O15078,Q03252,O15287,O96028,P48735,P31749,Q15051,Q9UQE7,P51809,Q15437,P31751,Q16740,Q96RK4,O75844,P49770,Q01844 27 +Involuntary movements 0.3139475104360129 0.1254237965473671 0.9001880499463 1.0 1.0 364 Q13045,Q99720,Q01105,P27544,P51114,O96008,O75027,O75503,P05067,Q9NR77,O60313,Q9BQT8,O95831,Q9H6K4,Q9NXR1,P00403,P03886,P07602,Q15233,P50897,P00846,Q9BWD1,Q9Y4W6,Q9Y4G8,O96028,P41440,Q96CU9,P17480,P31749,O00584,O43681,P07196,Q71SY5,P06280,Q9UHX1,P32929,Q6DKK2,Q03252,Q9NWW5,Q86VD7,Q14108,Q9HD42,Q8TD16,P11166,Q9UBX3,Q7Z406,O75787,Q9BPX6,Q96RR1,Q969N2,Q13813,P20700,O95155,Q96F07,Q9Y448,Q9H9S5,P11274,Q96N66,P61916,O75569,Q01082,Q9NQH7,Q96N67,O75298,O14773,Q8N0X7,Q14203,Q9BUB7,O14936,P55011,Q15056,Q8WXW3,Q7LG56,P51798,Q9NWS8,O75306,Q9NUQ7,Q9UIG0 78 +Pneumonia 0.2607346556752345 0.1253219224131003 0.900268697425135 1.0 1.0 60 Q13432,P16278,P20700,O00754,P49748,Q71SY5,P06753,Q9Y448,Q9NXR1,P00813,P49792 11 +Impaired glucose tolerance 0.3545762390291482 0.125191633508538 0.90037184062823 1.0 1.0 5 P02545,O76024 2 +Abnormal activity of mitochondrial respiratory chain 0.2603737625094069 0.1237628753061324 0.9015030269759738 1.0 1.0 58 P03886,Q70HW3,Q9UBX3,O43676,Q9Y2R0,O75380,Q7KZN9,Q96CU9 8 +Rod cone dystrophy 0.2624047896034889 0.1232042285010469 0.9019453772222792 1.0 1.0 46 P03886,Q13868,P00846,O15078 4 +Coarctation of aorta 0.2678337114222906 0.1221831031342317 0.9027540079322204 1.0 1.0 36 P55263,Q9UHX1,P46783,O14678,Q9UBM7 5 +Craniofacial osteosclerosis 0.381460885878195 0.1215876777575318 0.9032255728035136 1.0 1.0 3 P51798 1 +Hereditary nonpolyposis colorectal carcinoma 0.3117806777851887 0.1210649467867377 0.9036395933222008 1.0 1.0 8 O60566,P31749 2 +Pes planus 0.2640518845461372 0.1195793843145281 0.9048163514575448 1.0 1.0 86 Q13045,Q7RTS9,Q8N3U4,P02545,P06753,Q9UHX1,Q8WVQ1,Q96L58,Q9Y487,O75787,Q10713,Q5H8A4,Q96L73,Q15056,Q15233,O15287,P11274,P55795,Q15555,O75175,Q9UIG0 21 +Abnormal t cell subset distribution 0.297223535642665 0.1184301354158852 0.9057268491848108 1.0 1.0 14 Q9Y448,O75787 2 +Microtia third degree 0.3786113349745232 0.1175241168954269 0.9064447339487932 1.0 1.0 3 O75419 1 +Hypoplastic fifth toenail 0.3050676405522179 0.1169725201262925 0.9068818297253464 1.0 1.0 9 Q12824,P51532,Q8TAQ2,Q14738 4 +Back pain 0.2788413445900671 0.1167929370335856 0.9070241408774996 1.0 1.0 27 Q12824,Q8TAA9,P50402,Q8WXH0,P31749,P02545,Q01082,P51798,Q9UGP8,P50336 10 +Large for gestational age 0.3049241411652922 0.1166217092265268 0.907159833638722 1.0 1.0 9 Q969N2 1 +Aplasia hypoplasia involving the nose 0.2731375289071788 0.1164191605125814 0.9073203507517492 1.0 1.0 31 P55795,Q8N3U4,P02545,Q5KU26,P11274,O75431,O75844,Q8WYQ5 8 +Urinary tract neoplasm 0.2651823702041056 0.1158416773152438 0.9077780191236402 1.0 1.0 41 O60566,P54277,Q96L58,P51809,Q9NWH9,P35222,Q15437,P02545,P31749,Q96L73 10 +High narrow palate 0.2655195378575803 0.1106427676258421 0.91189963200831 1.0 1.0 38 Q15233,P23786,Q969N2,O75419,Q71SY5,Q01082,P06753,O60826,Q9Y619,P11274 10 +Macular purpura 0.2767008523437256 0.1105800518431518 0.9119493667809282 1.0 1.0 19 Q6UN15,Q8NCH0,P38435,P17301,P40818,Q14980,P40763,Q9BZK7,P51798,P04062,Q16625 11 +Abnormal pons morphology 0.2789552551566726 0.1098092598530899 0.912560647158234 1.0 1.0 25 Q9H9S5,O15078,Q96N67,O14936 4 +Trophic changes related to pain 0.3725274725274747 0.1092112952151128 0.913034901612298 1.0 1.0 3 O15269,Q6DD88 2 +Penetrating foot ulcers 0.3725274725274747 0.1092112952151128 0.913034901612298 1.0 1.0 3 O15269,Q6DD88 2 +Emg slow motor conduction 0.3725274725274747 0.1092112952151128 0.913034901612298 1.0 1.0 3 O15269,Q6DD88 2 +Abnormality of the inner ear 0.2969346232416857 0.1083110268730246 0.9137489758959588 1.0 1.0 11 Q15046,P31749 2 +Long palpebral fissure 0.2785544073419188 0.1082287384395635 0.9138142488662888 1.0 1.0 24 P20700,Q13555,Q01082 3 +Arnold chiari malformation 0.2769080422180039 0.1075591922032679 0.9143453690332132 1.0 1.0 27 O00754,Q9UNW9,Q8TAA9,Q15056,Q15233,Q9Y2U8,O75419,Q9BZK7,Q14839,Q9UIG0 10 +Abnormality of the urethra 0.2469024557958927 0.1068082850143177 0.9149410745872026 1.0 1.0 145 O15344,O75419,Q71SY5,P02545,O00192,Q9UBM7,Q96EK5,O60566,Q9UHX1,Q9UBX3,O75787,Q9BUB7,Q6PGP7,Q5H8A4,P29372,O95155,Q15046,O15078,Q15056,O96028,Q9UQE7,Q15555,P51809,P46783,Q01082,O60826,O75844,Q9UIG0 28 +Abnormality of the nasal bone 0.3588898048914749 0.1061851397632354 0.9154354610357648 1.0 1.0 4 P10644,P35222,O14974 3 +Hypoplastic female external genitalia 0.28511199549689 0.1056309775389214 0.9158751457202372 1.0 1.0 16 Q9UQE7,O95714,O75419,Q9Y619,Q15042 5 +Corneal scarring 0.3697802197802218 0.1056182600208851 0.9158852363856832 1.0 1.0 3 P09884,Q86XI2 2 +Plantar hyperkeratosis 0.2649380344384625 0.1054541652793433 0.9160154379381626 1.0 1.0 36 P16615,O75431,Q15437,P09493 4 +Immunologic hypersensitivity 0.264670223025772 0.1043406010054012 0.9168990587928632 1.0 1.0 34 O00192,Q01082,P00813,Q9NZ08 4 +Vertebral compression fracture 0.2742226758886398 0.104132037617055 0.9170645667141296 1.0 1.0 18 Q14108,O75718 2 +Persistent head lag 0.3090468196538961 0.1034809671896089 0.9175812543752008 1.0 1.0 7 Q01082 1 +Congenital nystagmus 0.2762848936254395 0.1029264619011007 0.9180213356720948 1.0 1.0 21 P00846 1 +Synovitis 0.3673076923076942 0.1024692729208639 0.9183842010993312 1.0 1.0 3 O14802,Q06124 2 +Abnormality of neuronal migration 0.2563304432776787 0.1008816766004565 0.9196443888477625 1.0 1.0 166 Q86XL3,Q01105,P07942,Q8TD16,Q71SY5,Q5KU26,Q9UBM7,Q9HC21,Q96EK5,Q16625,Q9Y487,Q15392,Q6ZXV5,O14936,P20700,P55011,O15078,P23786,Q8WXW3,O43505,P52732,Q03252,P11177,Q9H9S5,Q9Y3C6,Q9NWS8,Q15051,Q96N66,P35606,Q9NUQ7,Q8NAT1,Q9BSJ2,O60826,Q9UEY8 34 +Glomerulonephritis 0.2742726182479751 0.1005466243145089 0.9199103694998904 1.0 1.0 19 Q03252,O43707 2 +Carpal synostosis 0.3017881705639748 0.0997085396902625 0.9205757206396528 1.0 1.0 8 Q96L58,O75367,O75369,Q6DKJ4,Q9Y5S9,P21333,P16435 7 +Synostosis of carpals tarsals 0.3017881705639748 0.0997085396902625 0.9205757206396528 1.0 1.0 8 Q96L58,O75367,O75369,Q6DKJ4,Q9Y5S9,P21333,P16435 7 +Decreased circulating igg level 0.2913024207153946 0.0991175785513099 0.9210449151493492 1.0 1.0 14 P00813 1 +Bladder neoplasm 0.3008056665934895 0.0977165644774848 0.922157361955524 1.0 1.0 8 O60566,P31749 2 +Vomiting 0.2641990848841067 0.0975907069030905 0.9222573040972776 1.0 1.0 102 P39210,Q9UBM7,P06280,A2RRP1,P49748,O43676,O75251,P50336,P00403,P03886,P22695,Q15046,P07602,P23786,P00846,Q7LG56,Q96CU9,Q13423,Q9NWH9,O75306,Q01082,P11117,O75380 23 +Pointed chin 0.2634488607252568 0.0974809532009166 0.9223444593299206 1.0 1.0 37 P20700,O95155,Q15056,P52732,Q01082,P11274,Q96EK5 7 +Abnormality of circulating fibrinogen 0.3006877579092293 0.0974788103969167 0.9223461609363024 1.0 1.0 8 Q6UN15,P10644,Q14980,P40763,P06748,Q9BZK7,P23526 7 +Short thumb 0.2610193780278075 0.097475097752628 0.9223491091578936 1.0 1.0 43 Q9UQE7,Q8WVQ1,P46783,Q03252,Q9Y448,O96028,Q9UBM7 7 +Abnormality of the choanae 0.2629252254771696 0.0969960180382069 0.9227295566851216 1.0 1.0 39 Q9UQE7,P55011,O15287,O75419,P02545,O00192,Q9UBM7,O75844,P11274 9 +Spina bifida 0.2628997225255107 0.0968458936781494 0.9228487773172812 1.0 1.0 39 Q9UHX1,Q15056,O15078,O15287,Q9H9S5,O00192,Q9HC21,Q9UIG0 8 +Abnormality of the nail 0.2564248037117739 0.0965038301198664 0.923120432130363 1.0 1.0 129 P02545,Q9Y366,Q96L58,Q9Y487,P16615,Q14739,P42892,O14936,P23786,P52732,O75431,O75530,O96028,P78536,P11274,P04066,Q13555,O60826,O75844 19 +Fatiguable weakness of proximal limb muscles 0.3517727490058311 0.0964436596412301 0.9231682183305794 1.0 1.0 4 P06753 1 +Delayed eruption of teeth 0.2551068196218862 0.0964314739374578 0.9231778960084962 1.0 1.0 49 Q9UQE7,Q9Y487,Q96JJ3,P02545,P51798,O75844 6 +Abnormal circulating proteinogenic amino acid concentration 0.2630703423004072 0.0953199653800012 0.9240606847771884 1.0 1.0 37 Q9NUN5,P41440,P55263 3 +Myelomeningocele 0.3506457818082014 0.0949650182573211 0.9243426126938148 1.0 1.0 4 Q96ST3,O75845,Q8TAA9 3 +Anteverted ears 0.3216149409502835 0.0946262273420045 0.9246117168993302 1.0 1.0 2 P27635 1 +Cerebellar vermis atrophy 0.2949917446340058 0.0934244686385581 0.925566352362582 1.0 1.0 9 Q96S52,P07437,P47897,Q8WVX9,Q15334,Q13620,Q10713,Q9UHD1 8 +Bladder diverticulum 0.2942801406712153 0.0918449363811713 0.9268212408497876 1.0 1.0 9 Q15056,Q9UIG0 2 +Synostosis involving bones of the upper limbs 0.2664525441233459 0.0912291604742111 0.9273105048521956 1.0 1.0 32 Q9UQE7,Q15056,Q8WVQ1,Q96L58,O96028,Q9UIG0 6 +Macular thickening 0.3158959624309018 0.0882238919052694 0.9296987283598794 1.0 1.0 6 Q8WWY3,P04439 2 +Recurrent lower respiratory tract infections 0.2705176725826565 0.0878592175434425 0.9299885708912324 1.0 1.0 29 Q71SY5,P00813 2 +Generalized osteoporosis 0.3438527845144034 0.0864175464308271 0.931134499073569 1.0 1.0 4 P02545 1 +Platybasia 0.2995049504950571 0.0861884341579926 0.931316624699242 1.0 1.0 7 Q92890,Q92766,O00192,O75369,P53992,Q04721 6 +Scarring 0.2653568308101722 0.0856067038258901 0.9317790691441544 1.0 1.0 32 O43395,Q8NCH0,Q15555,Q8WWY3,Q96L58,Q9NWM8,Q9Y2U8,P04439,Q92542,P50336 10 +Impaired distal vibration sensation 0.2867413417852342 0.0853295347532073 0.9319994118162872 1.0 1.0 10 P20700,Q96RR1 2 +Male hypogonadism 0.2911392405063199 0.0850053166798659 0.9322571639118448 1.0 1.0 9 P51608,P41091,Q9P2D1,Q8WWQ0,O76024,P09884,Q9H1A4,O00170 8 +Aplasia hypoplasia of the thyroid gland 0.3284771852666358 0.0849598104119039 0.93229334178536 1.0 1.0 5 O15160,Q13428,Q15738,O14654 4 +Inflammation of the large intestine 0.2832094254014913 0.0846127290956291 0.932569279006428 1.0 1.0 15 Q6PGP7,P42224,P49748,Q9Y2V7 4 +Abnormal macular morphology 0.2717419842669883 0.0836194252595756 0.9333590219024815 1.0 1.0 27 Q8NHS3 1 +Hemifacial spasm 0.3271833545170536 0.0832310124189127 0.933667853937719 1.0 1.0 5 P31749,Q10713 2 +Chromosomal breakage induced by ionizing radiation 0.3271833545170528 0.0832310124189116 0.93366785393772 1.0 1.0 5 Q92878,P31749 2 +Tricuspid valve prolapse 0.3505494505494525 0.0831966626342104 0.9336951663736428 1.0 1.0 3 Q9NX14,P53701 2 +Abnormality of the uterus 0.2551475176624237 0.0823550591585512 0.934364372195144 1.0 1.0 59 Q9UQE7,P20585,O60566,O15287,Q15437,Q16740,O00192,Q9UBM7,O96028 9 +Pulmonary hemorrhage 0.2964796479648094 0.0810573820218809 0.9353963183319453 1.0 1.0 7 Q6UN15,P10644,Q14980,P40763,P06748,Q9BZK7 6 +Dyskinesia 0.2567552142680214 0.0808790194336555 0.9355381653603488 1.0 1.0 78 Q05639,Q01105,Q71SY5,P11166,Q9UBX3,Q9BPX6,O14936,P03886,P55011,P00846,Q9UBB6,Q96F07,Q9Y448,P04062,Q96N66,Q14139,P54277,O75569,O75306,Q9NUQ7 20 +Hypoplastic fifth fingernail 0.2918844566712651 0.0805136207403452 0.9358287636198166 1.0 1.0 8 Q12824,O14497,Q969G3,P51532,Q96GM5,Q68CP9,Q8TAQ2 7 +Abnormal mitral valve physiology 0.2565418335543151 0.0787729339981941 0.9372132326727396 1.0 1.0 45 O00754,Q15056,Q96L58,Q9NZ08,O75306,P02545,O75431,P09493,O75844,P06280 10 +Anorexia 0.265654380275891 0.0783590101994834 0.9375424783561191 1.0 1.0 31 Q14108,P06280,Q9NZ08 3 +Hydrocele testis 0.2905911319722188 0.0781516412835524 0.9377074289680004 1.0 1.0 8 Q9UBX3,P31749 2 +Chorioretinal hypopigmentation 0.345054945054947 0.0776403179606004 0.9381141700662352 1.0 1.0 3 Q9Y619,Q96AX1 2 +Peripheral edema 0.3045866520186707 0.0764178621559652 0.939086659211908 1.0 1.0 2 O95235 1 +Abnormal right atrium morphology 0.3045866520186707 0.0764178621559652 0.939086659211908 1.0 1.0 2 O95235 1 +Pulmonary venous hypertension 0.3045866520186707 0.0764178621559652 0.939086659211908 1.0 1.0 2 O95235 1 +Orthopnea 0.3045866520186707 0.0764178621559652 0.939086659211908 1.0 1.0 2 O95235 1 +Interstitial cardiac fibrosis 0.3045866520186707 0.0764178621559652 0.939086659211908 1.0 1.0 2 O95235 1 +Zonular cataract 0.2863756825259586 0.0758533270263123 0.93953578946106 1.0 1.0 13 P08670 1 +Type ii diabetes mellitus 0.2575074608838369 0.0758151797012777 0.9395661392289144 1.0 1.0 43 P03886,O43395,Q15555,Q15056,Q8WWY3,O95714,Q9UIG0,P02545,P31751,Q9Y6M1,O43172,P00403 12 +Congenital malformation of the great arteries 0.2597860681128399 0.0752650475694255 0.9400038305736318 1.0 1.0 117 P98175,Q8N3U4,P02545,O00192,Q9UBM7,Q9UHX1,Q15392,Q6ZXV5,P42892,Q6PGP7,Q969N2,Q8WYQ5,Q96L73,Q9Y3D3,O95155,Q15056,Q15233,O75530,O15287,P11274,Q9UQE7,O60826,O75844,Q9UIG0 24 +Spastic paraplegia 0.2541205288863029 0.0746020899532017 0.940531311217274 1.0 1.0 59 P31040,P11166,P07942,O00400,O60313,O00754,Q8N0X7,P00846,O75306,O95831,Q5MNZ6,O75251,O75298,P04062,Q9Y619,Q7KZN9,Q96CU9 17 +Abnormality of the anus 0.2512225217999947 0.0743394930913648 0.9407402530093883 1.0 1.0 51 O95155,O15344,P49748,P16615,O75419,Q9H9S5,O00192,O60826,P29372,P78536 10 +Thoracic aortic aneurysm 0.258912581106076 0.0737999866783336 0.9411695376272002 1.0 1.0 39 P55011,O95155,Q15056,Q96L58,P02545,P06753,Q8N3R9,O75844 8 +Abnormal tracheal morphology 0.2591794544259997 0.0735361081673887 0.941379511680061 1.0 1.0 37 P55011,Q15056,Q96L58,Q14739,Q96HY6,Q9UBM7,Q9UIG0 7 +Renovascular hypertension 0.2879041500158878 0.0733508449302177 0.9415269322307324 1.0 1.0 8 Q15056,Q9UIG0 2 +Abnormality of the abdominal organs 0.3133395041752937 0.0729749922564088 0.941826017728074 1.0 1.0 395 P22830,P55263,Q14108,O15118,Q9HC07,O43772,P14174,Q71SY5,P02545,P10253,P39210,P54802,O00192,Q9UBM7,Q7KZN9,P16278,P11717,P11166,Q9UHX1,Q8NCH0,P49748,P28070,O43676,P53985,Q15392,O75787,O75251,P15586,Q14739,P00813,Q96RR1,Q9BUB7,P10619,Q13049,P50336,O14936,P03886,O00754,O95155,P07602,O15078,Q15056,P23786,P00846,Q7LG56,Q03252,O43707,P08236,O75431,P51798,Q8N1F7,O96028,Q9BX67,P11274,Q96CU9,Q15051,P04066,P61916,Q9NZ08,Q9NWH9,Q15437,Q01082,P31751,O43681,Q96HY6,O75380,Q9NQH7,Q9NUN5 68 +Abnormality of fontanelles 0.2535702560808937 0.0713383250438878 0.9431284939402644 1.0 1.0 47 P20674,Q9UQE7,Q8NCH0,P98175,Q9Y487,O75718,O75419,P02545,Q93009,Q01082,Q9NXR1,O75844 12 +Pituitary hypothyroidism 0.2902153557997706 0.0709664091243315 0.9434244896967364 1.0 1.0 7 P35222,P31749 2 +Ecchymosis 0.2749566088240165 0.0703904217777066 0.94388291465353 1.0 1.0 16 Q6UN15,Q8NCH0,P38435,P17301,P40818,Q14980,P40763,Q9BZK7,P04062,O00170 10 +Enlarged posterior fossa 0.2535344820359735 0.0702103609363802 0.944026227843442 1.0 1.0 59 O00754,O60826,O15078,P49748,P23786,Q9Y487,O43505,Q8NAT1,P15291,Q9H9S5,Q9UBM7 11 +Abnormal cartilage morphology 0.2817111509754005 0.0698930868724756 0.9442787555512124 1.0 1.0 14 Q9UHX1 1 +Abnormal atrioventricular valve morphology 0.2575815085874229 0.0678626768606137 0.9458949497801284 1.0 1.0 40 Q15056,Q15233,Q96L58,P02545,P06753,O75431,O00192,O60826,O75844,Q9UIG0 10 +Abnormal vitreous humor morphology 0.2790557978530152 0.0674910160140442 0.9461908139014984 1.0 1.0 10 O15484,P35222,P04439 3 +Polycystic kidney dysplasia 0.2739320231131296 0.0670153560849939 0.9465694782946474 1.0 1.0 16 P23786,O00192 2 +Hypogonadism 0.2608636519785999 0.0642216737335273 0.9487937198725752 1.0 1.0 100 Q4J6C6,Q8IWS0,P02545,O60313,O43395,O95714,Q96RR1,Q13049,P00403,P03886,O95155,Q15056,O15078,Q7LG56,O95470,O15287,O43172,P31749,Q15555,Q8WWY3,P51809,Q93009,Q16740,Q96RK4,O75844,Q9UIG0 26 +Periventricular leukomalacia 0.2795599704974167 0.0636946299087829 0.9492133807780354 1.0 1.0 14 Q93009,P11177,Q9UHX1 3 +Right ventricular dilatation 0.2892062620159237 0.0635168199076778 0.9493549659379076 1.0 1.0 2 P19022 1 +Abnormal proximal phalanx morphology of the hand 0.3204176971695662 0.0615701918467227 0.95090511535017 1.0 1.0 4 P42345,Q9ULC3,Q14807 3 +Broad face 0.3204176971695647 0.0615701918467213 0.9509051153501712 1.0 1.0 4 P21333,Q9BZK7,Q6PJG6 3 +Abnormal urine protein level 0.2526212093663246 0.0613638796283512 0.9510694180064064 1.0 1.0 62 P31040,P35579,P03886,Q14108,Q15056,Q15046,P09601,O95470,Q9UIG0,P57740,O43707,Q03252,O75431,Q8N1F7,P04062,P06280,P00403 17 +Spina bifida occulta 0.2648684219531352 0.0601044902995443 0.9520724136892252 1.0 1.0 20 Q9UHX1,Q15056 2 +Deviation of the hand or of fingers of the hand 0.256856962606182 0.0575747916704315 0.9540873296882056 1.0 1.0 121 Q13045,Q7RTS9,Q8TD16,Q8N3U4,Q8WVM7,O75419,Q71SY5,P02545,Q9Y366,Q9UBM7,Q9Y619,O60566,Q9UHX1,Q8WVQ1,Q96L58,Q14739,Q9H6K4,O95155,Q15056,Q15233,Q03252,Q9Y448,O15287,P11274,P31749,Q9UQE7,Q93009,P42356,O75175,Q9UIG0 30 +Granulocytopenia 0.3157460840890465 0.0574347923862403 0.9541988484178496 1.0 1.0 4 P54819,Q9Y4L1,O75533 3 +Simple ear 0.3045629466740023 0.0568823107097259 0.9546389455039644 1.0 1.0 5 P16435,O60231,Q96KP1,Q92925 4 +Poikilocytosis 0.2664216220377103 0.0560435249767233 0.9553071337088213 1.0 1.0 17 P11166,P41440 2 +Generalized onset seizure 0.2596706910129019 0.0555533886174152 0.9556975976169256 1.0 1.0 109 Q05639,Q01105,Q14108,Q96N67,Q71SY5,O75503,Q9Y619,P16278,P11166,O60566,Q8NHS3,Q9NXR1,Q969N2,Q96L73,P03886,O14936,P55011,P07602,Q15046,P00846,Q9Y4W6,Q9UBB6,Q9Y448,P04062,O95239,Q96N66,Q14139,Q6PJT7,Q9NUQ7 29 +Inverted nipples 0.2770241984783254 0.0553680805128756 0.9558452248748086 1.0 1.0 8 Q969N2,Q15067 2 +Heteronymous hemianopia 0.2905735200304794 0.0542301924653481 0.9567517659619696 1.0 1.0 6 P35222,P31749 2 +Abnormal dental root morphology 0.2750624035206901 0.0533685447783526 0.9574382671129592 1.0 1.0 9 Q9Y366 1 +Abnormal dental pulp morphology 0.2750624035206901 0.0533685447783526 0.9574382671129592 1.0 1.0 9 Q9Y366 1 +Optic atrophy 0.2726592002234407 0.0528396659250349 0.9578596567914196 1.0 1.0 214 P07942,P98175,Q5KU26,O00192,Q9HC21,Q9UBM7,Q7KZN9,P06280,P16278,A2RRP1,O60313,O75251,Q6P4Q7,Q8NHS3,Q9H6K4,Q6ZXV5,Q9BPX6,Q96RR1,Q5H8A4,P00403,P03886,O14936,O95155,P07602,O15078,P50897,P00846,O43505,P52732,Q9Y4W6,Q96F07,Q9Y448,Q9H9S5,P51798,O96028,P41440,Q96CU9,Q15555,Q8WWY3,O75306,Q8NAT1,Q9BSJ2,O43681,O60826,O75175,P49770,Q9GZY8 47 +Aplasia hypoplasia of the patella 0.2890058952940721 0.0524547658591897 0.9581663372971962 1.0 1.0 6 Q9Y619,Q9Y5S9,O75419 3 +Pulmonic stenosis 0.2546328553454609 0.0512889159363162 0.9590953002825432 1.0 1.0 34 Q9UQE7,P55263,Q15056,O75306,O60826,Q9UIG0 6 +Renal cortical cysts 0.2878350449249394 0.0511527928324172 0.9592037684248595 1.0 1.0 6 O15078 1 +Hypoplasia of the pons 0.2618596729450063 0.0489120283583129 0.9609894030928614 1.0 1.0 20 Q9H9S5,Q96N67,O14936 3 +Chronic hepatic failure 0.3027856171489083 0.0472799634960104 0.9622900970354344 1.0 1.0 4 Q10713 1 +Leiomyosarcoma 0.2713849778648403 0.0469528419329275 0.9625508127296888 1.0 1.0 8 O60566,P31749 2 +Large fleshy ears 0.3016483516483537 0.0455668754116791 0.963655471327262 1.0 1.0 3 Q9BZK7,P21281 2 +Gastrointestinal hemorrhage 0.2536093698347121 0.0449237989571181 0.9641680471669556 1.0 1.0 35 P31040,P16930,Q9UHX1,P54277,Q9NZ08,Q02241,O76024,Q14739,P49257,O00192,Q9UGP8,P35222,Q9UJS0 13 +Aplasia hypoplasia of the ear 0.2503389771673233 0.0445964808476301 0.9644289477476172 1.0 1.0 61 Q15555,O95155,P98175,Q9NUN5,P46783,Q8N3U4,O75419,Q9H9S5,O96028,Q6PGP7,Q5H8A4 11 +Focal emotional seizure 0.269310367026475 0.0440096127575954 0.9648967414204916 1.0 1.0 8 Q05639,Q01105,Q96JM3,Q00610 4 +Tetralogy of fallot 0.2479093302315434 0.041675545005445 0.9667573492776872 1.0 1.0 48 Q9UHX1,Q15056,P98175,O95155,O60826,O00192,Q6PGP7,Q9UIG0 8 +Abnormality of the diaphragm 0.2602659649028098 0.0412086985934595 0.9671295190900184 1.0 1.0 29 O96028,Q9UBM7,Q5H8A4,Q9UQE7 4 +Arnold chiari type i malformation 0.2681665778261921 0.0410197525769186 0.967280148834682 1.0 1.0 7 Q9UNW9,Q15233,O75419 3 +Abnormal circulating aromatic amino acid concentration 0.2780008764817283 0.0410126995399403 0.967285771612318 1.0 1.0 6 Q9NVS9,P16930 2 +Short ribs 0.2686777479787692 0.0397412903629132 0.9682993827141056 1.0 1.0 11 Q96HY6,Q14739 2 +Abnormal drinking behavior 0.2907392140698137 0.0394622069058127 0.9685218845519064 1.0 1.0 4 Q9NQ48,Q6P1J9,O76024 3 +Upper motor neuron dysfunction 0.3119460977831883 0.0389853385528983 0.96890207786758 1.0 1.0 409 Q99720,P07942,Q86XL3,O15118,Q9HD42,Q7RTS9,Q8TD16,Q9UIG0,Q71SY5,Q5KU26,O75298,O75027,O14773,O75503,Q7KZN9,Q9NR77,P16278,P11166,Q9UBX3,Q8N0X7,Q96L58,Q9Y487,Q15392,O75787,O95831,O75251,Q14203,Q6ZXV5,Q969N2,Q13813,Q6DKK2,P50336,P03886,P20700,O14936,O00754,O95155,P07602,O15078,P50897,P55011,Q15056,P00846,O43505,P52732,Q7LG56,Q96F07,Q9H9S5,O75530,Q9BX67,P41440,Q96CU9,Q9Y3C6,Q15051,Q96N66,P04066,Q68CQ7,O00584,Q13423,P61916,O75569,Q9NZ08,P35606,Q15165,O75306,Q01082,P11117,Q9BSJ2,O43681,Q9NUQ7,P07196,Q9UEY8,Q9GZY8 73 +Abnormality of refraction 0.2530877493446115 0.0382707795179257 0.9694717882785348 1.0 1.0 169 Q13045,P98175,Q9HD42,O75419,Q71SY5,Q8N201,Q8N3R9,Q9Y366,A2RRP1,Q9UHX1,Q8WVQ1,Q8NCH0,Q96L58,Q9Y487,Q13868,Q969N2,Q5H8A4,O14936,O00754,P55011,O95155,Q15056,Q15233,P52732,P30533,Q9H9S5,O75530,O15287,Q9UQE7,Q15555,Q13555,Q15437,Q93009,Q9UIG0 34 +Anencephaly 0.2588989862510339 0.0382343075691598 0.9695008674004556 1.0 1.0 20 O00192,O43505,O15078 3 +Ischemic stroke 0.2835164835164857 0.0374419453102104 0.970132628581242 1.0 1.0 3 O00443,P18583 2 +Subarachnoid hemorrhage 0.2835164835164857 0.0374419453102101 0.9701326285812422 1.0 1.0 3 P17301,Q6YHK3 2 +Abnormal fear anxiety related behavior 0.254960581622944 0.0363291597292314 0.971019899179356 1.0 1.0 121 Q13045,Q8N3R9,O00192,O75503,P06280,P11166,Q8N0X7,Q14203,Q96RR1,P50336,Q6DKK2,P03886,P00403,O00754,P55011,Q15056,Q15233,Q7LG56,P55795,Q9UQE7,Q68CQ7,Q15165,Q01082,O75175,Q9UIG0 25 +Congenital onset 0.2528150166488598 0.0353375275772338 0.971810599327294 1.0 1.0 126 Q4J6C6,Q9HD42,Q8TD16,Q71SY5,Q5KU26,P06753,Q9HC21,Q96EK5,Q9UHX1,O14678,Q9NXR1,Q9BUB7,Q5H8A4,P20674,Q9Y3D3,P55011,P07602,Q15046,O43505,Q03252,Q9H9S5,O75530,Q9BX67,Q9NWS8,Q96N66,P08670,Q9NQT5,P25705 28 +Hyperpituitarism 0.25698880803079 0.0352758598721106 0.9718597723789067 1.0 1.0 19 Q12824,P51809,P57740,P35222,Q8IY37,P31749 6 +Aplasia hypoplasia of fingers 0.2574318166964269 0.0323559300164122 0.9741882068224648 1.0 1.0 98 Q9Y366,Q9UQE7,Q9UHX1,Q8WVQ1,Q9UBM7,Q03252,O95831,P02545,Q9Y448,P51798,O96028,O60826,O75844,P11274,O14936 15 +Impaired mastication 0.2599176584631532 0.031944487949044 0.9745163204745112 1.0 1.0 7 P06753,Q14738 2 +Lower limb hypertonia 0.2672024634298804 0.0315322550885198 0.9748450690871266 1.0 1.0 12 O00400,Q14739 2 +Erythrocyte inclusion bodies 0.2753793892163641 0.0315181143342211 0.9748563461714737 1.0 1.0 4 O14936 1 +Aplasia hypoplasia of the humerus 0.2611235501158059 0.0313583864316504 0.9749837276335728 1.0 1.0 10 O00116,O15228,Q9Y5S9 3 +Increased megakaryocyte count 0.2598901098901122 0.0303426447259727 0.975793786643175 1.0 1.0 3 O75533,P04637 2 +Abnormal cd4 cd8 ratio 0.2642287599670092 0.0290858970885666 0.9767960835333168 1.0 1.0 6 Q13432,Q9H0U3,O75083,P17812,O00203 5 +Abnormal number of granulocyte precursors 0.2513736263736288 0.0285570354864035 0.9772178788113834 1.0 1.0 3 Q01130,O75533 2 +Abnormality of the pancreas 0.2539158258214478 0.0257599999176019 0.9794487666942596 1.0 1.0 86 P03886,Q9UHX1,O95155,O15078,Q9NZ08,P53985,P14174,P02545,Q9NQH7 9 +Neuronal loss in the cerebral cortex 0.2609603567394208 0.0245504694659201 0.980413527017062 1.0 1.0 5 Q9NXR1 1 +Abnormal granulocytopoietic cell morphology 0.2514427040395784 0.0229296761803436 0.9817063684461352 1.0 1.0 4 Q01130,Q14980,O75533 3 +Abnormal cardiac ventricle morphology 0.2707797912272408 0.0219740728168342 0.982468637438102 1.0 1.0 215 O43772,O75419,Q71SY5,P02545,P06753,P10253,O00192,Q9UBM7,Q7KZN9,P06280,P13807,O60566,Q9UHX1,Q8WVQ1,P49748,Q96L58,O75787,O75251,Q14739,Q9NXR1,P42892,Q6PGP7,Q96RR1,P00403,P03886,O14936,P55011,Q15056,O15078,P23786,Q7LG56,Q9H9S5,O75431,P78536,O96028,P11274,Q96CU9,Q9UQE7,P46783,O75306,Q01082,O60826,O75844,Q9UIG0 44 +Abnormal neural tube morphology 0.2462978973192306 0.0214295028482827 0.9829030390963224 1.0 1.0 46 Q9UHX1,Q8TAA9,Q15056,O15078,Q9Y5P6,O15287,Q9UIG0,Q8N3U4,Q10713,Q9H9S5,Q9Y5S9,O00192,Q9HC21,Q99707,Q14683,Q14807 16 +Abnormal metabolism 0.2449469863500222 0.0213474769612904 0.9829684713168524 1.0 1.0 54 Q9Y487,O75787,O14678,P41440,Q9NUN5 5 +Primary microcephaly 0.2549764944903882 0.0195917179574889 0.9843690706792124 1.0 1.0 17 Q9UQE7,Q8NB90,Q03252,Q9NXR1,P35222 5 +Glucose intolerance 0.2530356557632486 0.019056737184305 0.984795843881878 1.0 1.0 122 P02545,O60313,O43395,O95714,Q96JJ3,O43676,O75251,Q9Y6M1,Q96RR1,Q96L73,P03886,P00403,Q15056,P00846,Q9Y2U8,Q7LG56,Q03252,O75431,Q96CU9,O43172,Q969M3,Q15555,Q8WWY3,O75306,P31751,O75380,O75844,Q9UIG0 28 +Abnormality of urine calcium concentration 0.2623633240802166 0.0189229937033163 0.984902536501174 1.0 1.0 14 Q969N2,Q15056 2 +Abnormality of cardiovascular system electrophysiology 0.2551047192129418 0.0188672154817616 0.9849470331390612 1.0 1.0 115 O43772,P02545,P06753,P10253,P06280,P49748,P42892,Q9BUB7,Q96RR1,P50336,P03886,P07602,Q15056,P23786,P00846,Q7LG56,P09493,O75306,Q8NFF5 19 +Lewy bodies 0.247388675096213 0.0185377106469033 0.9852098939822832 1.0 1.0 5 P04062,Q6Y7W6,Q96QK1,O75165 4 +Flat occiput 0.262045444983147 0.0181757846878685 0.9854986204653688 1.0 1.0 14 Q9BUB7,O00754,Q9Y2U8,P52732 4 +Abnormality iris morphology 0.2547574268289348 0.0172791374891331 0.98621392899148 1.0 1.0 92 Q9NR77,Q9UHX1,O95155,O15078,Q9UBM7,Q15056,Q8WXW3,O15287,O43505,Q86YV9,Q8NAT1,Q01082,Q9H9S5,Q96EK5,O96028,O60826,Q5H8A4,Q9UIG0 18 +Phimosis 0.2214894201703879 0.0169999948572927 0.9864366198751986 1.0 1.0 4 Q9UJX6,O60832,Q96L73 3 +Photophobia 0.247840772906216 0.0149966704338268 0.988034836693534 1.0 1.0 40 Q13432,O43395,Q15555,P07602,Q8WWY3,Q9NZ08,Q86YV9,Q9Y4W6,Q6P4Q7,P04439 10 +Oral cleft 0.2548708605577036 0.0148710442775164 0.9881350606874156 1.0 1.0 177 Q13045,O15344,P98175,Q8IWS0,Q8N3U4,Q8WVM7,O75419,Q71SY5,Q8N201,P02545,O00192,Q9HC21,Q9Y619,Q9UBM7,Q96EK5,O60566,Q9UHX1,Q8NCH0,Q96L58,Q15392,Q10713,Q14739,Q6PGP7,Q5H8A4,Q8WYQ5,P29372,O14936,Q15233,O15078,Q8WXW3,O43505,Q9H9S5,O15287,O96028,P11274,Q9UQE7,Q15555,Q9NX62,P46783,Q8NAT1,O60826,O75844,Q9NUN5 43 +Wide anterior fontanel 0.2537067865538142 0.013859335396544 0.9889422042643132 1.0 1.0 22 Q9Y487,O75718,O75419 3 +Aplasia hypoplasia of the distal phalanges of the hand 0.2473836002015457 0.0124929729114748 0.9900323090795972 1.0 1.0 37 P02545,Q9Y448,Q9Y366,O60826,O75844,P11274 6 +Abnormal number of incisors 0.2350838603244494 0.0114814235326287 0.9908393506918964 1.0 1.0 6 Q8N3U4,A5YKK6,P41227,Q14683,P54132 5 +Abnormal blistering of the skin 0.2536292470268761 0.0109679775205476 0.991248995526054 1.0 1.0 23 Q9NZ08,O95155,P50336 3 +Hypomimic face 0.2584489807991394 0.0099249967315601 0.9920811283508972 1.0 1.0 14 Q96RR1,O75787 2 +Decreased lacrimation 0.2332233223322416 0.009668908763056 0.9922854471810908 1.0 1.0 7 Q9NRG9,P55011,Q10567,O95163,Q03001,Q7Z392 6 +Pain in head and neck region 0.2379577856235081 0.0089322568312042 0.9928731849504572 1.0 1.0 8 Q12824,O75533,P31749 3 +Aplasia hypoplasia of the thumb 0.2430861638790464 0.007302188966724 0.9941737479412986 1.0 1.0 47 Q9UQE7,Q8WVQ1,P46783,Q03252,Q9Y448,O96028,Q9UBM7 7 +Mediastinal lymphadenopathy 0.1932380428807117 0.0068094089159971 0.9945669197446544 1.0 1.0 5 P01889,O15460,Q9H0U3,Q01844 4 +Displacement of the urethral meatus 0.2488510876355023 0.0064515670631886 0.9948524299566311 1.0 1.0 129 O15344,O75419,Q71SY5,P02545,O00192,Q9UBM7,Q96EK5,O60566,Q9UHX1,Q9UBX3,O75787,Q9BUB7,Q6PGP7,Q5H8A4,P29372,O95155,Q15046,O96028,Q9UQE7,Q15555,P51809,P46783,Q01082,O60826,O75844 25 +Hypophosphatemia 0.2213362661534319 0.0061429075963601 0.9950986996957958 1.0 1.0 6 P16930,P53680,Q6P1J9,P51798,Q01968 5 +Abnormal involuntary eye movements 0.2992754593803127 0.0056987454940284 0.995453083565099 1.0 1.0 319 Q05639,Q99720,O75175,Q9HD42,Q8IWS0,O43772,Q5KU26,O75027,Q8N3R9,P39210,O75503,Q9Y366,Q9UBM7,Q7KZN9,O14773,Q9P0J1,Q16625,Q9NR77,P11166,O60313,O60566,Q5THJ4,O00400,O43395,O43676,Q15392,O95831,O75251,Q13868,Q10713,Q6P4Q7,Q9H6K4,Q5JTZ9,Q96RR1,Q969N2,Q5H8A4,Q13049,Q9H061,Q6DKK2,O14936,P03886,P20700,O00754,P55011,O95155,P07602,Q8IV08,O15078,Q15056,Q8WXW3,Q15046,P00846,P52732,Q9Y4W6,Q96F07,P51798,O96028,O15287,P41440,Q96CU9,Q15051,Q9UQE7,Q15555,Q8WWY3,O00584,Q9NQT5,O75306,Q86YV9,P25705,Q93009,P42356,Q96RK4,O75380,P07196,Q9UEY8,Q9UIG0 76 +Hyperextensible skin 0.2462630755039188 0.0047030665442787 0.996247509649349 1.0 1.0 18 Q9NWM8,Q9UHX1,Q96L58,Q8NCH0 4 +Abnormal vascular morphology 0.2818336913710715 0.0042512069323934 0.996608037840888 1.0 1.0 251 P55263,P98175,O15118,Q71SY5,P02545,P06753,P10253,Q8N3R9,O00192,Q9UBM7,P05067,P16278,Q9UHX1,Q96L58,Q9Y487,Q15392,O75718,O14678,Q6ZXV5,P42892,Q969N2,P10619,P03886,Q9Y3D3,P55011,O95155,P07602,Q15056,P00846,Q9Y448,P08236,P51798,O75530,P11274,Q9UQE7,P61916,Q9NZ08,Q01082,O60826,O75844 40 +Progressive cerebellar ataxia 0.245629901237686 0.0037750582657011 0.9969879464478292 1.0 1.0 40 Q9Y487,P41440,Q7KZN9,Q96CU9 4 +Abnormal cns myelination 0.2406068344209705 0.0028671810506611 0.9977123236410452 1.0 1.0 148 P03886,Q99720,P07602,O00584,O43676,O75787,O95831,O75251,P10253,O43681,Q13813,O75380,Q7KZN9,Q96CU9 14 +Azoospermia 0.2553066527001713 0.0022743197357318 0.9981853569609132 1.0 1.0 13 O15287,P04062,Q13423,P51809 4 +Abnormality of the gastric mucosa 0.2486212800528651 0.0013413280831916 0.9989297753523678 1.0 1.0 17 Q15056,P50851,O76024,Q14739,P04062,Q6PGP7,Q9UIG0 7 +Abnormality of bladder morphology 0.2467642072306302 0.0001414075927622 0.9998871730653308 1.0 1.0 11 Q15056,Q9UIG0 2 diff --git a/msigdb_hp/selections.json b/msigdb_hp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..a59a4a9d559874cb742d234d993b0b2b84acac77 --- /dev/null +++ b/msigdb_hp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["11 pairs of ribs", "2 3 finger syndactyly", "2 3 toe cutaneous syndactyly", "2 3 toe syndactyly", "3 4 finger syndactyly", "3 methylglutaconic aciduria", "4 5 toe syndactyly", "Abdominal aortic aneurysm", "Abdominal distention", "Abdominal obesity", "Abdominal pain", "Abdominal wall muscle weakness", "Abducens palsy", "Abnormal 2nd finger morphology", "Abnormal 3rd finger morphology", "Abnormal 4th finger morphology", "Abnormal 5th finger morphology", "Abnormal 5th finger phalanx morphology", "Abnormal abdomen morphology", "Abnormal acetabulum morphology", "Abnormal activity of mitochondrial respiratory chain", "Abnormal adipose tissue morphology", "Abnormal aggressive impulsive or violent behavior", "Abnormal aldolase level", "Abnormal anatomic location of the heart", "Abnormal anterior chamber morphology", "Abnormal anterior eye segment morphology", "Abnormal anterior horn cell morphology", "Abnormal aortic arch morphology", "Abnormal aortic morphology", "Abnormal aortic valve cusp morphology", "Abnormal aortic valve morphology", "Abnormal aortic valve physiology", "Abnormal arachnoid mater morphology", "Abnormal arm span", "Abnormal arterial physiology", "Abnormal astrocyte morphology", "Abnormal atrial arrangement", "Abnormal atrioventricular conduction", "Abnormal atrioventricular valve morphology", "Abnormal atrioventricular valve physiology", "Abnormal auditory evoked potentials", "Abnormal autonomic nervous system physiology", "Abnormal b cell morphology", "Abnormal b cell subset distribution", "Abnormal basal ganglia mri signal intensity", "Abnormal basophil count", "Abnormal basophil morphology", "Abnormal biliary tract morphology", "Abnormal bleeding", "Abnormal blistering of the skin", "Abnormal blood carbon dioxide level", "Abnormal blood chloride concentration", "Abnormal blood gas level", "Abnormal blood glucose concentration", "Abnormal blood inorganic cation concentration", "Abnormal blood ion concentration", "Abnormal blood monovalent inorganic cation concentration", "Abnormal blood phosphate concentration", "Abnormal blood potassium concentration", "Abnormal blood sodium concentration", "Abnormal blood transition element cation concentration", "Abnormal blood zinc concentration", "Abnormal bone structure", "Abnormal bowel sounds", "Abnormal brain choline level by mrs", "Abnormal brain lactate level by mrs", "Abnormal brain n acetyl aspartate level by mrs", "Abnormal brain positron emission tomography", "Abnormal brainstem morphology", "Abnormal brainstem mri signal intensity", "Abnormal branching pattern of the aortic arch", "Abnormal breath sound", "Abnormal bronchoalveolar lavage fluid morphology", "Abnormal bronchus morphology", "Abnormal bronchus physiology", "Abnormal c peptide level", "Abnormal c reactive protein level", "Abnormal calcium phosphate regulating hormone level", "Abnormal cardiac atrium morphology", "Abnormal cardiac exercise stress test", "Abnormal cardiac septum morphology", "Abnormal cardiac test", "Abnormal cardiac ventricle morphology", "Abnormal cardiac ventricular function", "Abnormal cardiomyocyte morphology", "Abnormal carotid artery morphology", "Abnormal cartilage morphology", "Abnormal caudate nucleus morphology", "Abnormal cd4 cd8 ratio", "Abnormal cell morphology", "Abnormal cell proliferation", "Abnormal cellular composition of bronchoalveolar fluid", "Abnormal cellular phenotype", "Abnormal central sensory function", "Abnormal cerebellar vermis morphology", "Abnormal cerebral artery morphology", "Abnormal cerebral cortex morphology", "Abnormal cerebral vascular morphology", "Abnormal cerebral vein morphology", "Abnormal cerebral ventricle morphology", "Abnormal cerebrospinal fluid metabolite concentration", "Abnormal cervical curvature", "Abnormal cervical spine morphology", "Abnormal chorioretinal morphology", "Abnormal choroid morphology", "Abnormal choroid plexus morphology", "Abnormal chromosome morphology", "Abnormal ciliary body morphology", "Abnormal circulating acetylcarnitine concentration", "Abnormal circulating albumin concentration", "Abnormal circulating amino acid concentration", "Abnormal circulating amylase level", "Abnormal circulating androgen level", "Abnormal circulating apolipoprotein concentration", "Abnormal circulating arginine concentration", "Abnormal circulating aromatic amino acid concentration", "Abnormal circulating aspartate family amino acid concentration", "Abnormal circulating bilirubin concentration", "Abnormal circulating branched chain amino acid concentration", "Abnormal circulating carbohydrate concentration", "Abnormal circulating carboxylic acid concentration", "Abnormal circulating ceruloplasmin concentration", "Abnormal circulating cholesterol concentration", "Abnormal circulating citrulline concentration", "Abnormal circulating copper concentration", "Abnormal circulating creatinine concentration", "Abnormal circulating dehydroepiandrosterone concentration", "Abnormal circulating dicarboxylic acid concentration", "Abnormal circulating estrogen level", "Abnormal circulating fatty acid anion concentration", "Abnormal circulating fatty acid concentration", "Abnormal circulating ferritin concentration", "Abnormal circulating follicle stimulating hormone concentration", "Abnormal circulating free fatty acid concentration", "Abnormal circulating gaba concentration", "Abnormal circulating glutamine concentration", "Abnormal circulating glutamine family amino acid concentration", "Abnormal circulating glycine concentration", "Abnormal circulating gonadotropin concentration", "Abnormal circulating hormone concentration", "Abnormal circulating iga level", "Abnormal circulating ige level", "Abnormal circulating igg level", "Abnormal circulating igm level", "Abnormal circulating inhibin level", "Abnormal circulating lipid concentration", "Abnormal circulating long chain fatty acid concentration", "Abnormal circulating metabolite concentration", "Abnormal circulating methionine concentration", "Abnormal circulating monocarboxylic acid cocentration", "Abnormal circulating nitrogen compound concentration", "Abnormal circulating non proteinogenic amino acid concentration", "Abnormal circulating nucleobase concentration", "Abnormal circulating phenylalanine concentration", "Abnormal circulating porphyrin concentration", "Abnormal circulating progesterone level", "Abnormal circulating proline concentration", "Abnormal circulating protein concentration", "Abnormal circulating proteinogenic amino acid concentration", "Abnormal circulating proteinogenic amino acid derivative concentration", "Abnormal circulating pyruvate family amino acid concentration", "Abnormal circulating renin", "Abnormal circulating serine concentration", "Abnormal circulating serine family amino acid concentration", "Abnormal circulating sex hormone concentration", "Abnormal circulating sulfur amino acid concentration", "Abnormal circulating tyrosine concentration", "Abnormal clavicle morphology", "Abnormal cns myelination", "Abnormal cochlea morphology", "Abnormal conjugate eye movement", "Abnormal conjunctiva morphology", "Abnormal connection of the cardiac segments", "Abnormal consumption behavior", "Abnormal conus terminalis morphology", "Abnormal cornea morphology", "Abnormal corneal endothelium morphology", "Abnormal corneal epithelium morphology", "Abnormal coronary artery morphology", "Abnormal coronary sinus morphology", "Abnormal corpus callosum morphology", "Abnormal corpus striatum morphology", "Abnormal cortical bone morphology", "Abnormal cortical gyration", "Abnormal cranial nerve morphology", "Abnormal cranial nerve physiology", "Abnormal cry", "Abnormal csf carboxylic acid concentration", "Abnormal csf metabolite level", "Abnormal csf protein level", "Abnormal csf pyruvate family amino acid concentration", "Abnormal cutaneous elastic fiber morphology", "Abnormal delayed hypersensitivity skin test", "Abnormal delivery", "Abnormal dense granules", "Abnormal dental pulp morphology", "Abnormal dental root morphology", "Abnormal dentate nucleus morphology", "Abnormal dentin morphology", "Abnormal dermatoglyphics", "Abnormal dermoepidermal junction morphology", "Abnormal descemet membrane morphology", "Abnormal diaphysis morphology", "Abnormal distal phalanx morphology of finger", "Abnormal dlco", "Abnormal drinking behavior", "Abnormal duodenum morphology", "Abnormal dura mater morphology", "Abnormal eating behavior", "Abnormal echocardiogram", "Abnormal elasticity of skin", "Abnormal electrophysiology of sinoatrial node origin", "Abnormal electroretinogram", "Abnormal emotion affect behavior", "Abnormal enchondral ossification", "Abnormal endocardium morphology", "Abnormal endocrine physiology", "Abnormal enzyme coenzyme activity", "Abnormal eosinophil morphology", "Abnormal epidermal morphology", "Abnormal epiglottis morphology", "Abnormal epiphyseal ossification", "Abnormal epiphysis morphology of the phalanges of the hand", "Abnormal erythrocyte enzyme level", "Abnormal erythrocyte morphology", "Abnormal erythrocyte physiology", "Abnormal erythrocyte sedimentation rate", "Abnormal esophagus morphology", "Abnormal esophagus physiology", "Abnormal external genitalia", "Abnormal exteroceptive sensation", "Abnormal eyebrow morphology", "Abnormal eyelash morphology", "Abnormal eyelid morphology", "Abnormal eyelid physiology", "Abnormal facial expression", "Abnormal facial shape", "Abnormal factor ix activity", "Abnormal fallopian tube morphology", "Abnormal fear anxiety related behavior", "Abnormal female reproductive system physiology", "Abnormal femoral head morphology", "Abnormal femoral neck head morphology", "Abnormal femoral neck morphology", "Abnormal finger phalanx morphology", "Abnormal fingernail morphology", "Abnormal fingertip morphology", "Abnormal foot bone ossification", "Abnormal foramen magnum morphology", "Abnormal forearm bone morphology", "Abnormal form of the vertebral bodies", "Abnormal foveal morphology", "Abnormal full field electroretinogram", "Abnormal fundus autofluorescence imaging", "Abnormal gallbladder morphology", "Abnormal gastrointestinal motility", "Abnormal glial cell morphology", "Abnormal globus pallidus morphology", "Abnormal glomerular basement membrane morphology", "Abnormal glomerular filtration rate", "Abnormal glomerular mesangial cellularity", "Abnormal glomerular mesangium morphology", "Abnormal glucose homeostasis", "Abnormal glycosylation", "Abnormal granulocyte count", "Abnormal granulocytopoietic cell morphology", "Abnormal greater sciatic notch morphology", "Abnormal growth hormone level", "Abnormal hair laboratory examination", "Abnormal hair morphology", "Abnormal hair pattern", "Abnormal hair quantity", "Abnormal hair whorl", "Abnormal hand bone ossification", "Abnormal hand morphology", "Abnormal hdl cholesterol concentration", "Abnormal head movements", "Abnormal heart rate variability", "Abnormal heart sound", "Abnormal heart valve morphology", "Abnormal heart valve physiology", "Abnormal hemoglobin", "Abnormal hemoglobin concentration", "Abnormal hepatic iron concentration", "Abnormal humerus morphology", "Abnormal hypothalamus morphology", "Abnormal hypothalamus physiology", "Abnormal ileum morphology", "Abnormal iliac wing morphology", "Abnormal ilium morphology", "Abnormal immune system morphology", "Abnormal incisor morphology", "Abnormal inflammatory response", "Abnormal insulin level", "Abnormal internal carotid artery morphology", "Abnormal internal genitalia", "Abnormal intestine morphology", "Abnormal intraocular pressure", "Abnormal involuntary eye movements", "Abnormal iris pigmentation", "Abnormal jaw morphology", "Abnormal jejunum morphology", "Abnormal joint morphology", "Abnormal labia majora morphology", "Abnormal labia minora morphology", "Abnormal labia morphology", "Abnormal lacrimal duct morphology", "Abnormal lacrimal gland morphology", "Abnormal lactate dehydrogenase level", "Abnormal large intestine morphology", "Abnormal large intestine physiology", "Abnormal larynx morphology", "Abnormal larynx physiology", "Abnormal lateral ventricle morphology", "Abnormal ldl cholesterol concentration", "Abnormal left atrium morphology", "Abnormal left ventricle morphology", "Abnormal left ventricular outflow tract morphology", "Abnormal length of corpus callosum", "Abnormal leukocyte count", "Abnormal leukocyte physiology", "Abnormal levels of alpha fetoprotein", "Abnormal libido", "Abnormal light and dark adapted electroretinogram", "Abnormal lip morphology", "Abnormal liver morphology", "Abnormal liver parenchyma morphology", "Abnormal liver physiology", "Abnormal localization of kidney", "Abnormal location of ears", "Abnormal lower limb bone morphology", "Abnormal lower motor neuron morphology", "Abnormal lumbar spine morphology", "Abnormal lung development", "Abnormal lung lobation", "Abnormal lymphatic vessel morphology", "Abnormal lymphocyte morphology", "Abnormal macrophage morphology", "Abnormal macroscopic urine appearance", "Abnormal macular morphology", "Abnormal magnesium concentration", "Abnormal male reproductive system physiology", "Abnormal mandibular ramus morphology", "Abnormal mast cell morphology", "Abnormal mean corpuscular hemoglobin concentration", "Abnormal mean corpuscular volume", "Abnormal megakaryocyte morphology", "Abnormal meningeal morphology", "Abnormal metabolic brain imaging by mrs", "Abnormal metabolism", "Abnormal metacarpal morphology", "Abnormal metaphyseal trabeculation", "Abnormal metatarsal morphology", "Abnormal midbrain morphology", "Abnormal middle phalanx morphology of the hand", "Abnormal mitochondria in muscle tissue", "Abnormal mitochondrial morphology", "Abnormal mitochondrial number", "Abnormal mitochondrial shape", "Abnormal mitral valve physiology", "Abnormal monocyte morphology", "Abnormal morphology of myocardial trabeculae", "Abnormal morphology of the abdominal musculature", "Abnormal morphology of the choroidal vasculature", "Abnormal morphology of the conjunctival vasculature", "Abnormal morphology of the great vessels", "Abnormal morphology of the limbic system", "Abnormal morphology of the musculature of the neck", "Abnormal morphology of the olfactory bulb", "Abnormal morphology of the radius", "Abnormal motor evoked potentials", "Abnormal motor nerve conduction velocity", "Abnormal muscle fiber alpha dystroglycan", "Abnormal muscle fiber morphology", "Abnormal muscle fiber protein expression", "Abnormal muscle fiber type distribution", "Abnormal muscle glycogen content", "Abnormal myelination", "Abnormal myeloid cell morphology", "Abnormal myeloid leukocyte morphology", "Abnormal myocardium morphology", "Abnormal nasal base", "Abnormal nasal bridge morphology", "Abnormal nasal mucosa morphology", "Abnormal nasolacrimal system morphology", "Abnormal natural killer cell morphology", "Abnormal natural killer cell physiology", "Abnormal nephron morphology", "Abnormal nerve conduction velocity", "Abnormal nervous system electrophysiology", "Abnormal neural tube morphology", "Abnormal neuron morphology", "Abnormal neutrophil count", "Abnormal nipple morphology", "Abnormal number of erythroid precursors", "Abnormal number of granulocyte precursors", "Abnormal number of incisors", "Abnormal number of permanent teeth", "Abnormal number of teeth", "Abnormal odontoid tissue morphology", "Abnormal optical coherence tomography", "Abnormal oral frenulum morphology", "Abnormal oral glucose tolerance", "Abnormal oral mucosa morphology", "Abnormal oral physiology", "Abnormal ossification involving the femoral head and neck", "Abnormal ovarian morphology", "Abnormal ovarian physiology", "Abnormal palate morphology", "Abnormal palmar dermatoglyphics", "Abnormal pancreas morphology", "Abnormal pancreas size", "Abnormal paranasal sinus morphology", "Abnormal parietal bone morphology", "Abnormal parotid gland morphology", "Abnormal patella morphology", "Abnormal pattern of respiration", "Abnormal pelvis bone morphology", "Abnormal pelvis bone ossification", "Abnormal penis morphology", "Abnormal pericardium morphology", "Abnormal peripheral action potential amplitude", "Abnormal peripheral myelination", "Abnormal peripheral nervous system morphology", "Abnormal peripheral nervous system physiology", "Abnormal peristalsis", "Abnormal periventricular white matter morphology", "Abnormal phalangeal joint morphology of the hand", "Abnormal pharynx morphology", "Abnormal pigmentation of the oral mucosa", "Abnormal pineal morphology", "Abnormal placenta morphology", "Abnormal placental membrane morphology", "Abnormal placental size", "Abnormal platelet aggregation", "Abnormal platelet function", "Abnormal platelet granules", "Abnormal platelet morphology", "Abnormal platelet volume", "Abnormal pleura morphology", "Abnormal pons morphology", "Abnormal posterior segment imaging", "Abnormal posturing", "Abnormal pr interval", "Abnormal preputium morphology", "Abnormal prolactin level", "Abnormal proportion of cd4 positive t cells", "Abnormal proportion of cd8 positive t cells", "Abnormal proportion of class switched memory b cells", "Abnormal proportion of double negative alpha beta regulatory t cell", "Abnormal prostate morphology", "Abnormal protein glycosylation", "Abnormal protein o linked glycosylation", "Abnormal proximal phalanx morphology of the hand", "Abnormal pulmonary interstitial morphology", "Abnormal pulmonary thoracic imaging finding", "Abnormal pulmonary valve morphology", "Abnormal pulmonary valve physiology", "Abnormal pupil morphology", "Abnormal pupillary function", "Abnormal pupillary light reflex", "Abnormal pyramidal sign", "Abnormal qrs complex", "Abnormal qt interval", "Abnormal rapid eye movement sleep", "Abnormal rectum morphology", "Abnormal reflex", "Abnormal renal collecting system morphology", "Abnormal renal cortex morphology", "Abnormal renal corticomedullary differentiation", "Abnormal renal echogenicity", "Abnormal renal insterstitial morphology", "Abnormal renal medulla morphology", "Abnormal renal morphology", "Abnormal renal pelvis morphology", "Abnormal renal physiology", "Abnormal renal resorption", "Abnormal renal tubule morphology", "Abnormal renal vascular morphology", "Abnormal respiratory motile cilium morphology", "Abnormal respiratory motile cilium physiology", "Abnormal respiratory system morphology", "Abnormal response to acth stimulation test", "Abnormal response to endocrine stimulation test", "Abnormal response to insulin tolerance test", "Abnormal reticulocyte morphology", "Abnormal retinal artery morphology", "Abnormal retinal morphology", "Abnormal retinal vascular morphology", "Abnormal rib cage morphology", "Abnormal rib ossification", "Abnormal right atrium morphology", "Abnormal right ventricle morphology", "Abnormal right ventricular function", "Abnormal saccadic eye movements", "Abnormal sacroiliac joint morphology", "Abnormal sacrum morphology", "Abnormal salivary gland morphology", "Abnormal sarcomere morphology", "Abnormal scalp morphology", "Abnormal scapula morphology", "Abnormal sclera morphology", "Abnormal scrotal rugation", "Abnormal sella turcica morphology", "Abnormal sensory nerve conduction velocity", "Abnormal serum insulin like growth factor 1 level", "Abnormal serum interferon level", "Abnormal serum interleukin level", "Abnormal serum iron concentration", "Abnormal sex determination", "Abnormal shape of the frontal region", "Abnormal shape of the occiput", "Abnormal shape of the palpebral fissure", "Abnormal sharpey fiber morphology", "Abnormal shoulder morphology", "Abnormal shoulder physiology", "Abnormal size of pituitary gland", "Abnormal size of the clitoris", "Abnormal size of the palpebral fissures", "Abnormal skin morphology of the palm", "Abnormal social behavior", "Abnormal soft palate morphology", "Abnormal speech prosody", "Abnormal sperm motility", "Abnormal spermatogenesis", "Abnormal spinal meningeal morphology", "Abnormal sputum", "Abnormal st segment", "Abnormal sternal ossification", "Abnormal sternum morphology", "Abnormal stomach morphology", "Abnormal stool composition", "Abnormal subarachnoid space morphology", "Abnormal subclavian artery morphology", "Abnormal subcutaneous fat tissue distribution", "Abnormal substantia nigra morphology", "Abnormal superior cerebellar peduncle morphology", "Abnormal sweat gland morphology", "Abnormal sweat homeostasis", "Abnormal synaptic transmission at the neuromuscular junction", "Abnormal systemic arterial morphology", "Abnormal systemic blood pressure", "Abnormal t cell activation", "Abnormal t cell morphology", "Abnormal t cell proliferation", "Abnormal t cell subset distribution", "Abnormal t wave", "Abnormal talus morphology", "Abnormal tarsal ossification", "Abnormal temper tantrums", "Abnormal temporal bone morphology", "Abnormal tendon morphology", "Abnormal testis morphology", "Abnormal thalamic mri signal intensity", "Abnormal thalamic size", "Abnormal thoracic spine morphology", "Abnormal thorax morphology", "Abnormal thrombocyte morphology", "Abnormal thrombosis", "Abnormal thumb morphology", "Abnormal thyroid hormone level", "Abnormal thyroid morphology", "Abnormal thyroid stimulating hormone level", "Abnormal tissue metabolite concentration", "Abnormal toenail morphology", "Abnormal tongue morphology", "Abnormal tongue physiology", "Abnormal trabecular bone morphology", "Abnormal tracheal morphology", "Abnormal tracheobronchial morphology", "Abnormal transferrin saturation", "Abnormal tricuspid valve morphology", "Abnormal tricuspid valve physiology", "Abnormal umbilicus morphology", "Abnormal upper limb bone morphology", "Abnormal upper motor neuron morphology", "Abnormal ureter morphology", "Abnormal ureter physiology", "Abnormal urinary color", "Abnormal urinary electrolyte concentration", "Abnormal urine alpha ketoglutarate concentration", "Abnormal urine carbohydrate level", "Abnormal urine carboxylic acid level", "Abnormal urine cytology", "Abnormal urine hormone level", "Abnormal urine magnesium concentration", "Abnormal urine metabolite level", "Abnormal urine ph", "Abnormal urine phosphate concentration", "Abnormal urine potassium concentration", "Abnormal urine protein level", "Abnormal urine sodium concentration", "Abnormal uterus morphology", "Abnormal uvea morphology", "Abnormal uvula morphology", "Abnormal vagina morphology", "Abnormal vascular morphology", "Abnormal vascular physiology", "Abnormal vena cava morphology", "Abnormal venous morphology", "Abnormal ventricular septum morphology", "Abnormal vertebral morphology", "Abnormal vertebral segmentation and fusion", "Abnormal vestibulo ocular reflex", "Abnormal visual electrophysiology", "Abnormal visual field test", "Abnormal visual fixation", "Abnormal vitamin b12 level", "Abnormal vitreous humor morphology", "Abnormal waist to hip ratio", "Abnormal z disc morphology", "Abnormalities of placenta or umbilical cord", "Abnormality iris morphology", "Abnormality of abdominal situs", "Abnormality of acid base homeostasis", "Abnormality of adrenal morphology", "Abnormality of adrenal physiology", "Abnormality of alkaline phosphatase level", "Abnormality of amino acid metabolism", "Abnormality of bladder morphology", "Abnormality of blood circulation", "Abnormality of blood volume homeostasis", "Abnormality of body mass index", "Abnormality of bone marrow cell morphology", "Abnormality of bone mineral density", "Abnormality of canine", "Abnormality of cardiovascular system electrophysiology", "Abnormality of carpal bone ossification", "Abnormality of cartilage of external ear", "Abnormality of central nervous system electrophysiology", "Abnormality of chorioretinal pigmentation", "Abnormality of chromosome segregation", "Abnormality of chromosome stability", "Abnormality of circulating adrenocorticotropin level", "Abnormality of circulating enzyme level", "Abnormality of circulating fibrinogen", "Abnormality of circulating glucocorticoid level", "Abnormality of circulating leptin level", "Abnormality of coagulation", "Abnormality of complement system", "Abnormality of coordination", "Abnormality of corneal size", "Abnormality of corneal stroma", "Abnormality of corneal thickness", "Abnormality of cranial sutures", "Abnormality of cytokine secretion", "Abnormality of dental color", "Abnormality of dental eruption", "Abnormality of dental morphology", "Abnormality of dental structure", "Abnormality of dermal melanosomes", "Abnormality of digestive system morphology", "Abnormality of dna repair", "Abnormality of earlobe", "Abnormality of endocrine pancreas physiology", "Abnormality of epiphysis morphology", "Abnormality of exocrine pancreas physiology", "Abnormality of extrapyramidal motor function", "Abnormality of facial adipose tissue", "Abnormality of facial musculature", "Abnormality of facial skeleton", "Abnormality of facial soft tissue", "Abnormality of female external genitalia", "Abnormality of femur morphology", "Abnormality of fibula morphology", "Abnormality of finger", "Abnormality of fluid regulation", "Abnormality of folate metabolism", "Abnormality of fontanelles", "Abnormality of foveal pigmentation", "Abnormality of frontal sinus", "Abnormality of frontalis muscle belly", "Abnormality of fundus pigmentation", "Abnormality of globe location", "Abnormality of globe size", "Abnormality of glycolipid metabolism", "Abnormality of hair growth", "Abnormality of hair pigmentation", "Abnormality of hair texture", "Abnormality of hand joint mobility", "Abnormality of head blood vessel", "Abnormality of hepatobiliary system physiology", "Abnormality of hindbrain morphology", "Abnormality of humoral immunity", "Abnormality of immune serum protein physiology", "Abnormality of iron homeostasis", "Abnormality of krebs cycle metabolism", "Abnormality of lens shape", "Abnormality of limb epiphysis morphology", "Abnormality of lipoprotein cholesterol concentration", "Abnormality of long bone morphology", "Abnormality of lower limb epiphysis morphology", "Abnormality of lower limb joint", "Abnormality of lower limb metaphyses", "Abnormality of lower lip", "Abnormality of lysosomal metabolism", "Abnormality of macular pigmentation", "Abnormality of malar bones", "Abnormality of male internal genitalia", "Abnormality of masticatory muscle", "Abnormality of metacarpal epiphyses", "Abnormality of metacarpophalangeal joint", "Abnormality of mouth shape", "Abnormality of mouth size", "Abnormality of muscle size", "Abnormality of nail color", "Abnormality of neuronal migration", "Abnormality of neutrophil morphology", "Abnormality of neutrophil physiology", "Abnormality of neutrophils", "Abnormality of ocular smooth pursuit", "Abnormality of pain sensation", "Abnormality of pancreas physiology", "Abnormality of pelvic girdle bone morphology", "Abnormality of periauricular region", "Abnormality of peripheral nerves", "Abnormality of prenatal development or birth", "Abnormality of primary teeth", "Abnormality of prothrombin", "Abnormality of pulmonary circulation", "Abnormality of refraction", "Abnormality of renal excretion", "Abnormality of renin angiotensin system", "Abnormality of reproductive system physiology", "Abnormality of retinal pigmentation", "Abnormality of salivation", "Abnormality of secondary sexual hair", "Abnormality of skeletal maturation", "Abnormality of skeletal muscle fiber size", "Abnormality of skin adnexa physiology", "Abnormality of skin physiology", "Abnormality of skin pigmentation", "Abnormality of skull ossification", "Abnormality of small intestinal villus morphology", "Abnormality of somatosensory evoked potentials", "Abnormality of subcutaneous fat tissue", "Abnormality of t cell physiology", "Abnormality of taste sensation", "Abnormality of temperature regulation", "Abnormality of thalamus morphology", "Abnormality of the 1st metacarpal", "Abnormality of the 2nd toe", "Abnormality of the 3rd toe", "Abnormality of the 4th metacarpal", "Abnormality of the 5th metacarpal", "Abnormality of the 5th toe", "Abnormality of the abdominal organs", "Abnormality of the abdominal wall", "Abnormality of the achilles tendon", "Abnormality of the adrenal glands", "Abnormality of the alveolar ridges", "Abnormality of the amniotic fluid", "Abnormality of the ankles", "Abnormality of the anterior fontanelle", "Abnormality of the antihelix", "Abnormality of the antitragus", "Abnormality of the anus", "Abnormality of the auditory canal", "Abnormality of the autonomic nervous system", "Abnormality of the axillary hair", "Abnormality of the basal ganglia", "Abnormality of the biliary system", "Abnormality of the bladder", "Abnormality of the brainstem white matter", "Abnormality of the breast", "Abnormality of the calcaneus", "Abnormality of the calf", "Abnormality of the calf musculature", "Abnormality of the calvaria", "Abnormality of the carpal bones", "Abnormality of the cerebral subcortex", "Abnormality of the cerebrospinal fluid", "Abnormality of the cervical spine", "Abnormality of the cheek", "Abnormality of the chin", "Abnormality of the choanae", "Abnormality of the clitoris", "Abnormality of the coagulation cascade", "Abnormality of the columella", "Abnormality of the common coagulation pathway", "Abnormality of the costochondral junction", "Abnormality of the crus of the helix", "Abnormality of the curvature of the cornea", "Abnormality of the curvature of the vertebral column", "Abnormality of the dentition", "Abnormality of the diaphragm", "Abnormality of the diencephalon", "Abnormality of the distal phalanges of the toes", "Abnormality of the distal phalanx of the hallux", "Abnormality of the distal phalanx of the thumb", "Abnormality of the dorsal column of the spinal cord", "Abnormality of the elbow", "Abnormality of the endometrium", "Abnormality of the epididymis", "Abnormality of the epiphyses of the distal phalanx of finger", "Abnormality of the external nose", "Abnormality of the extraocular muscles", "Abnormality of the extrinsic pathway", "Abnormality of the female genitalia", "Abnormality of the fetal cardiovascular system", "Abnormality of the fifth metatarsal bone", "Abnormality of the first metatarsal bone", "Abnormality of the fontanelles or cranial sutures", "Abnormality of the foot musculature", "Abnormality of the forearm", "Abnormality of the forehead", "Abnormality of the frontal hairline", "Abnormality of the gallbladder", "Abnormality of the gastric mucosa", "Abnormality of the gingiva", "Abnormality of the glabella", "Abnormality of the glenoid fossa", "Abnormality of the hairline", "Abnormality of the hallux", "Abnormality of the helix", "Abnormality of the hepatic vasculature", "Abnormality of the humeroradial joint", "Abnormality of the humerus", "Abnormality of the hypothalamus pituitary axis", "Abnormality of the hypothenar eminence", "Abnormality of the incisor", "Abnormality of the inner ear", "Abnormality of the internal auditory canal", "Abnormality of the intervertebral disk", "Abnormality of the intrahepatic bile duct", "Abnormality of the intrinsic pathway", "Abnormality of the ischium", "Abnormality of the kidney", "Abnormality of the knee", "Abnormality of the larynx", "Abnormality of the lens", "Abnormality of the leydig cells", "Abnormality of the liver", "Abnormality of the lower urinary tract", "Abnormality of the lymph nodes", "Abnormality of the lymphatic system", "Abnormality of the mastoid", "Abnormality of the maxilla", "Abnormality of the menstrual cycle", "Abnormality of the metacarpal bones", "Abnormality of the metaphysis", "Abnormality of the metopic suture", "Abnormality of the middle ear", "Abnormality of the middle ear ossicles", "Abnormality of the middle phalanges of the toes", "Abnormality of the middle phalanx of the 5th finger", "Abnormality of the midface", "Abnormality of the mitochondrion", "Abnormality of the musculature of the hand", "Abnormality of the musculature of the limbs", "Abnormality of the musculature of the lower limbs", "Abnormality of the musculature of the thigh", "Abnormality of the musculature of the upper arm", "Abnormality of the musculature of the upper limbs", "Abnormality of the nail", "Abnormality of the nasal alae", "Abnormality of the nasal bone", "Abnormality of the nasal cavity", "Abnormality of the nasal dorsum", "Abnormality of the nasal septum", "Abnormality of the nasal skeleton", "Abnormality of the nasal tip", "Abnormality of the nasolabial region", "Abnormality of the neck", "Abnormality of the odontoid process", "Abnormality of the optic nerve", "Abnormality of the outer ear", "Abnormality of the ovary", "Abnormality of the palm", "Abnormality of the palpebral fissures", "Abnormality of the pancreas", "Abnormality of the parathyroid gland", "Abnormality of the parathyroid morphology", "Abnormality of the periorbital region", "Abnormality of the peripheral nervous system", "Abnormality of the peritoneum", "Abnormality of the periungual region", "Abnormality of the phalanges of the hallux", "Abnormality of the phalanges of the toes", "Abnormality of the pharynx", "Abnormality of the philtrum", "Abnormality of the pineal gland", "Abnormality of the pinna", "Abnormality of the pituitary gland", "Abnormality of the plantar skin of foot", "Abnormality of the posterior pituitary", "Abnormality of the protein c anticoagulant pathway", "Abnormality of the proximal phalanx of the thumb", "Abnormality of the pubic bone", "Abnormality of the pubic hair", "Abnormality of the pulmonary artery", "Abnormality of the pulmonary vasculature", "Abnormality of the pulmonary veins", "Abnormality of the pylorus", "Abnormality of the radial head", "Abnormality of the radioulnar joints", "Abnormality of the ribs", "Abnormality of the scrotum", "Abnormality of the sense of smell", "Abnormality of the septum pellucidum", "Abnormality of the shoulder girdle musculature", "Abnormality of the skull base", "Abnormality of the small intestine", "Abnormality of the spinal cord", "Abnormality of the spinocerebellar tracts", "Abnormality of the spleen", "Abnormality of the stapes", "Abnormality of the subungual region", "Abnormality of the supraorbital ridges", "Abnormality of the synovia", "Abnormality of the tarsal bones", "Abnormality of the temporomandibular joint", "Abnormality of the testis size", "Abnormality of the thenar eminence", "Abnormality of the thoracic cavity", "Abnormality of the thymus", "Abnormality of the thyroid gland", "Abnormality of the tongue", "Abnormality of the tongue muscle", "Abnormality of the tonsils", "Abnormality of the tragus", "Abnormality of the ulna", "Abnormality of the umbilical cord", "Abnormality of the upper arm", "Abnormality of the upper respiratory tract", "Abnormality of the ureter", "Abnormality of the urethra", "Abnormality of the urinary system physiology", "Abnormality of the uterus", "Abnormality of the vasculature of the eye", "Abnormality of the vertebral endplates", "Abnormality of the vestibulocochlear nerve", "Abnormality of the voice", "Abnormality of the wrist", "Abnormality of the zygomatic bone", "Abnormality of thyroid physiology", "Abnormality of tibia morphology", "Abnormality of toe", "Abnormality of tumor necrosis factor secretion", "Abnormality of ulnar metaphysis", "Abnormality of upper limb epiphysis morphology", "Abnormality of upper limb joint", "Abnormality of upper limb metaphysis", "Abnormality of upper lip", "Abnormality of upper lip vermillion", "Abnormality of urinary uric acid concentration", "Abnormality of urine calcium concentration", "Abnormality of urine catecholamine concentration", "Abnormality of urine homeostasis", "Abnormality of visual evoked potentials", "Abnormality of vitamin a metabolism", "Abnormality of vitamin b metabolism", "Abnormality of vitamin b12 metabolism", "Abnormality of vitamin d metabolism", "Abnormality of vitamin e metabolism", "Abnormality of vitamin k metabolism", "Abnormality of vitamin metabolism", "Abnormality on pulmonary function testing", "Abnormally folded helix", "Abnormally large globe", "Abnormally lax or hyperextensible skin", "Abnormally low pitched voice", "Abnormally ossified vertebrae", "Abnormally shaped carpal bones", "Abscess", "Absence of pubertal development", "Absence of secondary sex characteristics", "Absence of subcutaneous fat", "Absence of the sacrum", "Absent axillary hair", "Absent brainstem auditory responses", "Absent distal phalanges", "Absent earlobe", "Absent epiphyses", "Absent eyebrow", "Absent facial hair", "Absent fingernail", "Absent forearm bone", "Absent foveal reflex", "Absent frontal sinuses", "Absent hair", "Absent hand", "Absent hypoplastic paranasal sinuses", "Absent nares", "Absent nipple", "Absent or minimally ossified vertebral bodies", "Absent outer dynein arms", "Absent palmar crease", "Absent septum pellucidum", "Absent shortened dynein arms", "Absent speech", "Absent sternal ossification", "Absent testis", "Absent thumb", "Absent thumbnail", "Absent tibia", "Absent toe", "Absent toenail", "Acanthocytosis", "Acantholysis", "Acanthosis nigricans", "Accelerated atherosclerosis", "Accelerated skeletal maturation", "Accessory oral frenulum", "Accessory spleen", "Acetabular dysplasia", "Acetabular spurs", "Achilles tendon contracture", "Achromatopsia", "Acidemia", "Acne", "Acne inversa", "Acquired abnormal hair pattern", "Acral blistering", "Acral ulceration", "Acromesomelia", "Acromicria", "Acroparesthesia", "Action tremor", "Acute coronary syndrome", "Acute encephalopathy", "Acute hepatic failure", "Acute kidney injury", "Acute leukemia", "Acute lymphoblastic leukemia", "Acute myeloid leukemia", "Acute pancreatitis", "Acute phase response", "Addictive behavior", "Adducted thumb", "Adenocarcinoma of the colon", "Adenocarcinoma of the intestines", "Adenocarcinoma of the small intestine", "Adenoma sebaceum", "Adenomatous colonic polyposis", "Adipose tissue loss", "Adrenal hyperplasia", "Adrenal hypoplasia", "Adrenal insufficiency", "Adrenal overactivity", "Adrenocortical abnormality", "Adrenocortical carcinoma", "Adrenocorticotropic hormone deficiency", "Adrenocorticotropic hormone excess", "Adrenocorticotropin deficient adrenal insufficiency", "Adult onset", "Advanced eruption of teeth", "Advanced ossification of carpal bones", "Agammaglobulinemia", "Aganglionic megacolon", "Agenesis of central incisor", "Agenesis of cerebellar vermis", "Agenesis of corpus callosum", "Agenesis of incisor", "Agenesis of lateral incisor", "Agenesis of maxillary incisor", "Agenesis of permanent teeth", "Aggressive behavior", "Agitation", "Agnosia", "Agyria", "Airway obstruction", "Akinesia", "Alacrima", "Albinism", "Albuminuria", "Alexia", "Alkalosis", "Allergic rhinitis", "Allergy", "Alopecia", "Alopecia of scalp", "Alopecia totalis", "Alopecia universalis", "Alternating esotropia", "Alveolar cell carcinoma", "Alveolar rhabdomyosarcoma", "Alveolar ridge overgrowth", "Alzheimer disease", "Amaurosis fugax", "Ambiguous genitalia", "Ambiguous genitalia female", "Ambiguous genitalia male", "Amblyopia", "Amegakaryocytic thrombocytopenia", "Amelogenesis imperfecta", "Amenorrhea", "Aminoaciduria", "Amniotic constriction ring", "Amyloidosis", "Amyotrophic lateral sclerosis", "Anal atresia", "Anal fissure", "Anal stenosis", "Anaphylactic shock", "Anarthria", "Anasarca", "Anemia of inadequate production", "Anencephaly", "Angina pectoris", "Angioedema", "Angiofibromas", "Angioid streaks of the fundus", "Angiokeratoma", "Angular cheilitis", "Anhidrosis", "Aniridia", "Anisocoria", "Anisocytosis", "Anisopoikilocytosis", "Anisospondyly", "Ankle clonus", "Ankle flexion contracture", "Ankle weakness", "Ankyloblepharon", "Ankyloglossia", "Ankylosis", "Annular pancreas", "Anodontia", "Anomalous trichromacy", "Anomic aphasia", "Anonychia", "Anophthalmia", "Anorectal anomaly", "Anorexia", "Anosmia", "Anotia", "Antenatal onset", "Anterior chamber synechiae", "Anterior open bite malocclusion", "Anterior pituitary dysgenesis", "Anterior plagiocephaly", "Anterior rib cupping", "Anterior synechiae of the anterior chamber", "Anterior uveitis", "Anteriorly placed anus", "Anteverted ears", "Anti thyroid peroxidase antibody positivity", "Antineutrophil antibody positivity", "Antinuclear antibody positivity", "Antiphospholipid antibody positivity", "Aortic aneurysm", "Aortic arch aneurysm", "Aortic atherosclerotic lesion", "Aortic dissection", "Aortic regurgitation", "Aortic root aneurysm", "Aortic valve calcification", "Aortic valve stenosis", "Aphasia", "Aphthous ulcer", "Aplasia cutis congenita", "Aplasia cutis congenita of scalp", "Aplasia cutis congenita on trunk or limbs", "Aplasia cutis congenita over the scalp vertex", "Aplasia hypoplasia affecting bones of the axial skeleton", "Aplasia hypoplasia affecting the anterior segment of the eye", "Aplasia hypoplasia affecting the eye", "Aplasia hypoplasia affecting the fundus", "Aplasia hypoplasia involving bones of the feet", "Aplasia hypoplasia involving bones of the lower limbs", "Aplasia hypoplasia involving bones of the thorax", "Aplasia hypoplasia involving bones of the upper limbs", "Aplasia hypoplasia involving forearm bones", "Aplasia hypoplasia involving the carpal bones", "Aplasia hypoplasia involving the femoral head and neck", "Aplasia hypoplasia involving the metacarpal bones", "Aplasia hypoplasia involving the musculature of the upper limbs", "Aplasia hypoplasia involving the nose", "Aplasia hypoplasia involving the pelvis", "Aplasia hypoplasia involving the sinuses", "Aplasia hypoplasia involving the skeletal musculature", "Aplasia hypoplasia involving the skeleton", "Aplasia hypoplasia involving the vertebral column", "Aplasia hypoplasia of fingers", "Aplasia hypoplasia of metatarsal bones", "Aplasia hypoplasia of the 4th metacarpal", "Aplasia hypoplasia of the 5th finger", "Aplasia hypoplasia of the 5th metacarpal", "Aplasia hypoplasia of the abdominal wall musculature", "Aplasia hypoplasia of the bladder", "Aplasia hypoplasia of the breasts", "Aplasia hypoplasia of the capital femoral epiphysis", "Aplasia hypoplasia of the cerebellar vermis", "Aplasia hypoplasia of the cerebellum", "Aplasia hypoplasia of the cerebral white matter", "Aplasia hypoplasia of the clavicles", "Aplasia hypoplasia of the colon", "Aplasia hypoplasia of the distal phalanges of the hand", "Aplasia hypoplasia of the distal phalanx of the thumb", "Aplasia hypoplasia of the ear", "Aplasia hypoplasia of the earlobes", "Aplasia hypoplasia of the epiglottis", "Aplasia hypoplasia of the extremities", "Aplasia hypoplasia of the eyebrow", "Aplasia hypoplasia of the eyelid", "Aplasia hypoplasia of the femur", "Aplasia hypoplasia of the fibula", "Aplasia hypoplasia of the gallbladder", "Aplasia hypoplasia of the hallux", "Aplasia hypoplasia of the humerus", "Aplasia hypoplasia of the lungs", "Aplasia hypoplasia of the middle phalanges of the toes", "Aplasia hypoplasia of the nails", "Aplasia hypoplasia of the nasal bone", "Aplasia hypoplasia of the nasal septum", "Aplasia hypoplasia of the nipples", "Aplasia hypoplasia of the optic nerve", "Aplasia hypoplasia of the ovary", "Aplasia hypoplasia of the palmar creases", "Aplasia hypoplasia of the patella", "Aplasia hypoplasia of the phalanges of the hand", "Aplasia hypoplasia of the phalanges of the thumb", "Aplasia hypoplasia of the phalanges of the toes", "Aplasia hypoplasia of the proximal phalanges of the hand", "Aplasia hypoplasia of the pubic bone", "Aplasia hypoplasia of the radius", "Aplasia hypoplasia of the retina", "Aplasia hypoplasia of the ribs", "Aplasia hypoplasia of the sacrum", "Aplasia hypoplasia of the scapulae", "Aplasia hypoplasia of the skin", "Aplasia hypoplasia of the spleen", "Aplasia hypoplasia of the sternum", "Aplasia hypoplasia of the thumb", "Aplasia hypoplasia of the thymus", "Aplasia hypoplasia of the thyroid gland", "Aplasia hypoplasia of the tibia", "Aplasia hypoplasia of the tongue", "Aplasia hypoplasia of the tragus", "Aplasia hypoplasia of the ulna", "Aplasia hypoplasia of the uterus", "Aplasia hypoplasia of the uvula", "Aplasia hypoplasia of the vagina", "Aplasia hypoplasia of toe", "Aplasia involving bones of the extremities", "Aplasia involving bones of the lower limbs", "Aplasia of the fingers", "Aplasia of the middle phalanx of the hand", "Aplasia of the phalanges of the hand", "Aplasia of the phalanges of the toes", "Aplasia of the semicircular canal", "Aplasia of the uterus", "Aplastic anemia", "Aplastic clavicle", "Aplastic hypoplastic lacrimal glands", "Aplastic hypoplastic toenail", "Apnea", "Apneic episodes in infancy", "Apneic episodes precipitated by illness fatigue stress", "Appendicular hypotonia", "Apraxia", "Aqueductal stenosis", "Arachnodactyly", "Arachnoid hemangiomatosis", "Areflexia", "Areflexia of lower limbs", "Arm dystonia", "Arnold chiari malformation", "Arnold chiari type i malformation", "Arrhinencephaly", "Arteria lusoria", "Arterial dissection", "Arterial rupture", "Arterial stenosis", "Arterial thrombosis", "Arteriosclerosis", "Arteriovenous malformation", "Arthralgia", "Arthritis", "Arthrogryposis multiplex congenita", "Arthropathy", "Ascending aortic dissection", "Ascending tubular aorta aneurysm", "Ascites", "Aspiration", "Aspiration pneumonia", "Asterixis", "Asthenia", "Asthma", "Astigmatism", "Astrocytoma", "Astrocytosis", "Asymmetric growth", "Asymmetric septal hypertrophy", "Asymmetry of spinal facet joints", "Asymmetry of the ears", "Asymmetry of the thorax", "Atelectasis", "Athetosis", "Atlantoaxial abnormality", "Atlantoaxial dislocation", "Atlantoaxial instability", "Atonic seizure", "Atopic dermatitis", "Atresia of the external auditory canal", "Atrial arrhythmia", "Atrial flutter", "Atrioventricular canal defect", "Atrophic scars", "Atrophy degeneration affecting the brainstem", "Atrophy degeneration affecting the central nervous system", "Atrophy degeneration affecting the cerebrum", "Atrophy degeneration involving the caudate nucleus", "Atrophy degeneration involving the corticospinal tracts", "Atrophy degeneration involving the spinal cord", "Atrophy of alveolar ridges", "Attention deficit hyperactivity disorder", "Attenuation of retinal blood vessels", "Atypical absence seizure", "Auditory hallucinations", "Autism", "Autistic behavior", "Autoamputation", "Autoamputation of digits", "Autoimmune antibody positivity", "Autoimmune hemolytic anemia", "Autoimmune thrombocytopenia", "Autoimmunity", "Autophagic vacuoles", "Autosomal dominant germline de novo mutation", "Avascular necrosis", "Avascular necrosis of the capital femoral epiphysis", "Axial dystonia", "Axial muscle weakness", "Axillary pterygium", "Axonal degeneration", "Axonal degeneration regeneration", "Axonal loss", "Axonal regeneration", "Azoospermia", "B cell lymphoma", "B lymphocytopenia", "Babinski sign", "Back pain", "Bacterial endocarditis", "Barrel shaped chest", "Barrett esophagus", "Basal cell carcinoma", "Basal ganglia calcification", "Basal ganglia cysts", "Basal ganglia gliosis", "Basilar impression", "Basilar invagination", "Beaded ribs", "Beaking of vertebral bodies", "Bell shaped thorax", "Benign neoplasm of the central nervous system", "Bicarbonaturia", "Biconcave vertebral bodies", "Bicornuate uterus", "Bifid epiglottis", "Bifid nasal tip", "Bifid ribs", "Bifid scrotum", "Bifid tongue", "Bifid uterus", "Bifid uvula", "Bilateral camptodactyly", "Bilateral cleft lip", "Bilateral cleft lip and palate", "Bilateral cleft palate", "Bilateral coxa valga", "Bilateral cryptorchidism", "Bilateral external ear deformity", "Bilateral microphthalmos", "Bilateral polymicrogyria", "Bilateral ptosis", "Bilateral sensorineural hearing impairment", "Bilateral single transverse palmar creases", "Bilateral talipes equinovarus", "Bilateral tonic clonic seizure", "Bilateral tonic clonic seizure with focal onset", "Bilateral tonic clonic seizure with generalized onset", "Bile duct proliferation", "Biliary atresia", "Biliary cirrhosis", "Biliary tract abnormality", "Biliary tract neoplasm", "Bimanual synkinesia", "Biparietal narrowing", "Bird like facies", "Birth length greater than 97th percentile", "Birth length less than 3rd percentile", "Biventricular hypertrophy", "Bladder diverticulum", "Bladder neoplasm", "Bleeding with minor or no trauma", "Blepharitis", "Blepharophimosis", "Blindness", "Blistering by anatomical location", "Blistering by histological location", "Bloodstream infectious agent", "Bloody diarrhea", "Blue irides", "Blue nevus", "Blue sclerae", "Blurred vision", "Bone cyst", "Bone fracture", "Bone marrow foam cells", "Bone marrow hypercellularity", "Bone marrow hypocellularity", "Bone pain", "Bone spicule pigmentation of the retina", "Bowel diverticulosis", "Bowing of the arm", "Bowing of the legs", "Brachycephaly", "Brachydactyly", "Brachyturricephaly", "Bradycardia", "Bradykinesia", "Brain imaging abnormality", "Brain neoplasm", "Brain stem compression", "Branchial anomaly", "Branchial cyst", "Branchial fistula", "Breast aplasia", "Breast carcinoma", "Breast hypoplasia", "Breathing dysregulation", "Breech presentation", "Brisk reflexes", "Brittle hair", "Broad alveolar ridges", "Broad based gait", "Broad chin", "Broad clavicles", "Broad columella", "Broad distal phalanx of finger", "Broad eyebrow", "Broad face", "Broad femoral neck", "Broad finger", "Broad foot", "Broad forehead", "Broad hallux phalanx", "Broad jaw", "Broad long bones", "Broad metacarpals", "Broad metatarsal", "Broad nail", "Broad nasal tip", "Broad neck", "Broad palm", "Broad phalanx of the toes", "Broad philtrum", "Broad ribs", "Broad thumb", "Broad toe", "Bronchiectasis", "Bronchitis", "Bronchomalacia", "Bronchospasm", "Bruising susceptibility", "Brushfield spots", "Bruxism", "Bulbar palsy", "Bulbar signs", "Bulbous nose", "Bull s eye maculopathy", "Bundle branch block", "Buphthalmos", "Burkitt lymphoma", "Butterfly vertebrae", "Cachexia", "Caesarian section", "Cafe au lait spot", "Calcific stippling", "Calcification of cartilage", "Calcification of the aorta", "Calcinosis", "Calcium nephrolithiasis", "Calcium oxalate nephrolithiasis", "Calf muscle pseudohypertrophy", "Calvarial hyperostosis", "Calvarial osteosclerosis", "Calvarial skull defect", "Camptodactyly of toe", "Capillary hemangioma", "Capillary malformation", "Capitate hamate fusion", "Carcinoid tumor", "Carcinoma", "Cardiac arrest", "Cardiac conduction abnormality", "Cardiac diverticulum", "Cardiac shunt", "Cardiac valve calcification", "Cardiomegaly", "Cardiorespiratory arrest", "Cardiovascular calcification", "Carious teeth", "Carpal bone hypoplasia", "Carpal synostosis", "Cataplexy", "Caudate atrophy", "Cavernous hemangioma", "Cavum septum pellucidum", "Celiac disease", "Cellular immunodeficiency", "Cellulitis", "Central adrenal insufficiency", "Central apnea", "Central diabetes insipidus", "Central heterochromia", "Central hypothyroidism", "Central hypoventilation", "Central nervous system cyst", "Central opacification of the cornea", "Central primitive neuroectodermal tumor", "Central scotoma", "Central sleep apnea", "Central y shaped metacarpal", "Centrally nucleated skeletal muscle fibers", "Centrocecal scotoma", "Cephalohematoma", "Cerebellar atrophy", "Cerebellar cortical atrophy", "Cerebellar cyst", "Cerebellar dysplasia", "Cerebellar hemorrhage", "Cerebellar hypoplasia", "Cerebellar malformation", "Cerebellar vermis atrophy", "Cerebral amyloid angiopathy", "Cerebral calcification", "Cerebral cortical atrophy", "Cerebral cortical hemiatrophy", "Cerebral dysmyelination", "Cerebral edema", "Cerebral hamartoma", "Cerebral hemorrhage", "Cerebral hypomyelination", "Cerebral hypoplasia", "Cerebral inclusion bodies", "Cerebral palsy", "Cerebral venous thrombosis", "Cerebral visual impairment", "Cerebral white matter atrophy", "Cerebral white matter hypoplasia", "Cervical kyphosis", "Cervical myelopathy", "Cervical ribs", "Cervical spinal canal stenosis", "Cervical spine instability", "Cervical subluxation", "Cessation of head growth", "Cheilitis", "Cherry red spot of the macula", "Chest pain", "Chilblains", "Childhood onset", "Childhood onset sensorineural hearing impairment", "Childhood onset truncal obesity", "Chills", "Chin with horizontal crease", "Choanal stenosis", "Choking episodes", "Cholangiocarcinoma", "Cholangitis", "Cholecystitis", "Cholestasis", "Cholestatic liver disease", "Chondrocalcinosis", "Chondrosarcoma", "Chordee", "Chorea", "Choreoathetosis", "Choriocarcinoma", "Chorioretinal atrophy", "Chorioretinal coloboma", "Chorioretinal degeneration", "Chorioretinal dysplasia", "Chorioretinal dystrophy", "Chorioretinal hypopigmentation", "Choroid plexus carcinoma", "Choroid plexus cyst", "Choroidal melanoma", "Choroidal neovascularization", "Chromosomal breakage induced by crosslinking agents", "Chromosomal breakage induced by ionizing radiation", "Chromosome breakage", "Chronic atrophic gastritis", "Chronic axonal neuropathy", "Chronic bronchitis", "Chronic constipation", "Chronic diarrhea", "Chronic fatigue", "Chronic hemolytic anemia", "Chronic hepatic failure", "Chronic infection", "Chronic kidney disease", "Chronic leukemia", "Chronic lung disease", "Chronic lymphatic leukemia", "Chronic mucocutaneous candidiasis", "Chronic myelogenous leukemia", "Chronic neutropenia", "Chronic noninfectious lymphadenopathy", "Chronic oral candidiasis", "Chronic otitis media", "Chronic pulmonary obstruction", "Chronic rhinitis", "Chronic sinusitis", "Chylothorax", "Cigarette paper scars", "Cirrhosis", "Cleft hard palate", "Cleft lip", "Cleft soft palate", "Cleft upper lip", "Clinodactyly", "Clinodactyly of the 2nd finger", "Clinodactyly of the 3rd finger", "Clinodactyly of the 4th finger", "Clitoral hypoplasia", "Clonic seizure", "Clonus", "Cloverleaf skull", "Clubbing", "Clubbing of fingers", "Clubbing of toes", "Clumsiness", "Cns demyelination", "Cns hypomyelination", "Coarctation of aorta", "Coarse facial features", "Coarse hair", "Cochlear malformation", "Cognitive impairment", "Cogwheel rigidity", "Cold induced muscle cramps", "Colitis", "Collectionism", "Coloboma", "Colon cancer", "Color vision defect", "Color vision test abnormality", "Colorectal polyposis", "Colpocephaly", "Coma", "Combined immunodeficiency", "Communicating hydrocephalus", "Complete atrioventricular canal defect", "Complete duplication of phalanx of hand", "Complex febrile seizure", "Concave nail", "Concave nasal ridge", "Concentric hypertrophic cardiomyopathy", "Cone cone rod dystrophy", "Cone shaped epiphyses of the phalanges of the hand", "Cone shaped epiphysis", "Confetti like hypopigmented macules", "Confusion", "Congenital adrenal hyperplasia", "Congenital bilateral hip dislocation", "Congenital blindness", "Congenital contracture", "Congenital craniofacial dysostosis", "Congenital diaphragmatic hernia", "Congenital hemolytic anemia", "Congenital hepatic fibrosis", "Congenital hip dislocation", "Congenital hypothyroidism", "Congenital ichthyosiform erythroderma", "Congenital localized absence of skin", "Congenital malformation of the great arteries", "Congenital malformation of the left heart", "Congenital malformation of the right heart", "Congenital muscular dystrophy", "Congenital muscular torticollis", "Congenital nonbullous ichthyosiform erythroderma", "Congenital nystagmus", "Congenital onset", "Congenital posterior urethral valve", "Congenital sensorineural hearing impairment", "Congenital stationary night blindness", "Congenital thrombocytopenia", "Congestive heart failure", "Conical tooth", "Conjugated hyperbilirubinemia", "Conjunctival hamartoma", "Connective tissue nevi", "Conspicuously happy disposition", "Constipation", "Constitutional symptom", "Constriction of peripheral visual field", "Contiguous gene syndrome", "Contractures involving the joints of the feet", "Contractures of the joints of the lower limbs", "Contractures of the joints of the upper limbs", "Contractures of the large joints", "Convex nasal ridge", "Coombs positive hemolytic anemia", "Cor pulmonale", "Corneal dystrophy", "Corneal erosion", "Corneal neovascularization", "Corneal opacity", "Corneal scarring", "Corneal ulceration", "Coronal cleft vertebrae", "Coronal craniosynostosis", "Coronary artery aneurysm", "Coronary artery atherosclerosis", "Corpus callosum atrophy", "Cortical cataract", "Cortical dysplasia", "Cortical myoclonus", "Cortical thickening of long bone diaphyses", "Corticospinal tract hypoplasia", "Cough", "Coxa valga", "Coxa vara", "Crackles", "Cranial asymmetry", "Cranial hyperostosis", "Cranial nerve compression", "Craniofacial asymmetry", "Craniofacial dysostosis", "Craniofacial hyperostosis", "Craniofacial osteosclerosis", "Craniosynostosis", "Crumpled long bones", "Cryptorchidism", "Csf lymphocytic pleiocytosis", "Csf pleocytosis", "Cubitus valgus", "Cupped ear", "Cupped ribs", "Curly eyelashes", "Curly hair", "Cutaneous abscess", "Cutaneous amyloidosis", "Cutaneous cyst", "Cutaneous finger syndactyly", "Cutaneous melanoma", "Cutaneous photosensitivity", "Cutaneous syndactyly", "Cutaneous syndactyly of toes", "Cutis laxa", "Cutis marmorata", "Cyanosis", "Cyanotic episode", "Cyclopia", "Cystathioninemia", "Cystic hygroma", "Cystic liver disease", "Cystic renal dysplasia", "Cystinuria", "Cystoid macular edema", "Cytochrome c oxidase negative muscle fibers", "Dark urine", "Death in adolescence", "Death in adulthood", "Death in childhood", "Death in infancy", "Decerebrate rigidity", "Decreased absent ankle reflexes", "Decreased achilles reflex", "Decreased activity of mitochondrial complex i", "Decreased activity of mitochondrial complex ii", "Decreased activity of mitochondrial complex iii", "Decreased activity of mitochondrial complex iv", "Decreased activity of nadph oxidase", "Decreased activity of the pyruvate dehydrogenase complex", "Decreased adenosylcobalamin", "Decreased adipose tissue", "Decreased calvarial ossification", "Decreased cd4 cd8 ratio", "Decreased cervical spine flexion due to contractures of posterior cervical muscles", "Decreased cervical spine mobility", "Decreased circulating acth level", "Decreased circulating aldosterone level", "Decreased circulating androgen concentration", "Decreased circulating antibody level", "Decreased circulating copper concentration", "Decreased circulating cortisol level", "Decreased circulating follicle stimulating hormone concentration", "Decreased circulating gaba concentration", "Decreased circulating gonadotropin concentration", "Decreased circulating iga level", "Decreased circulating igg level", "Decreased circulating igg subclass level", "Decreased circulating level of specific antibody", "Decreased circulating progesterone", "Decreased circulating total iga", "Decreased circulating total igg", "Decreased circulating total igm", "Decreased corneal reflex", "Decreased csf homovanillic acid", "Decreased facial expression", "Decreased fertility", "Decreased fertility in females", "Decreased fertility in males", "Decreased head circumference", "Decreased lacrimation", "Decreased ldl cholesterol concentration", "Decreased libido", "Decreased light and dark adapted electroretinogram amplitude", "Decreased lymphocyte apoptosis", "Decreased lymphocyte proliferation in response to anti cd3", "Decreased lymphocyte proliferation in response to mitogen", "Decreased mean corpuscular volume", "Decreased methylcobalamin", "Decreased methylmalonyl coa mutase activity", "Decreased muscle mass", "Decreased number of large peripheral myelinated nerve fibers", "Decreased number of peripheral myelinated nerve fibers", "Decreased palmar creases", "Decreased patellar reflex", "Decreased plasma carnitine", "Decreased proportion of cd3 positive t cells", "Decreased proportion of cd4 positive helper t cells", "Decreased proportion of cd8 positive t cells", "Decreased pulmonary function", "Decreased serum complement c3", "Decreased serum complement c4", "Decreased serum insulin like growth factor 1", "Decreased serum iron", "Decreased size of nerve terminals", "Decreased specific anti polysaccharide antibody level", "Decreased specific antibody response to protein vaccine", "Decreased specific antibody response to vaccination", "Decreased specific pneumococcal antibody level", "Decreased testicular size", "Decreased urine output", "Deep palmar crease", "Deep philtrum", "Deep plantar creases", "Deep set nails", "Deep venous thrombosis", "Deeply set eye", "Defective dna repair after ultraviolet radiation damage", "Defective t cell proliferation", "Deformed rib cage", "Deformed sella turcica", "Deformed tarsal bones", "Degeneration of the lateral corticospinal tracts", "Degeneration of the striatum", "Dehydration", "Delayed ability to roll over", "Delayed ability to sit", "Delayed ability to stand", "Delayed ability to walk", "Delayed closure of the anterior fontanelle", "Delayed cns myelination", "Delayed cranial suture closure", "Delayed epiphyseal ossification", "Delayed eruption of permanent teeth", "Delayed eruption of primary teeth", "Delayed eruption of teeth", "Delayed fine motor development", "Delayed gross motor development", "Delayed menarche", "Delayed myelination", "Delayed ossification of carpal bones", "Delayed proximal femoral epiphyseal ossification", "Delayed puberty", "Delayed social development", "Delirium", "Delusions", "Dementia", "Demyelinating peripheral neuropathy", "Dental crowding", "Dental malocclusion", "Depletion of mitochondrial dna in muscle tissue", "Deposits immunoreactive to beta amyloid protein", "Depressed nasal bridge", "Depressed nasal ridge", "Depressed nasal tip", "Depression", "Dermal atrophy", "Dermal translucency", "Dermatochalasis", "Dermatological manifestations of systemic disorders", "Dermoid cyst", "Descending aortic dissection", "Desquamation of skin soon after birth", "Developmental cataract", "Developmental glaucoma", "Developmental regression", "Developmental stagnation", "Deviated nasal septum", "Deviation of the 2nd finger", "Deviation of the 3rd finger", "Deviation of the 4th finger", "Deviation of the hallux", "Deviation of the hand or of fingers of the hand", "Deviation of the thumb", "Deviation of toes", "Diabetes insipidus", "Dialeptic seizure", "Diaphragmatic eventration", "Diaphragmatic paralysis", "Diaphragmatic weakness", "Diaphyseal sclerosis", "Diaphyseal thickening", "Diarrhea", "Diastasis recti", "Diastema", "Dicarboxylic aciduria", "Difficulty climbing stairs", "Difficulty in tongue movements", "Difficulty running", "Difficulty standing", "Difficulty walking", "Diffuse alveolar hemorrhage", "Diffuse cerebellar atrophy", "Diffuse cerebral atrophy", "Diffuse mesangial sclerosis", "Diffuse optic disc pallor", "Diffuse palmoplantar hyperkeratosis", "Diffuse white matter abnormalities", "Digenic inheritance", "Digital flexor tenosynovitis", "Dilatation of the cerebral artery", "Dilatation of the ventricular cavity", "Dilated cardiomyopathy", "Dilated fourth ventricle", "Dilated third ventricle", "Dilation of lateral ventricles", "Dilation of virchow robin spaces", "Diminished ability to concentrate", "Diminished motivation", "Diminished movement", "Dimple chin", "Diplopia", "Disinhibition", "Displacement of the urethral meatus", "Disproportionate short limb short stature", "Disproportionate short stature", "Disproportionate short trunk short stature", "Disproportionate tall stature", "Disseminated intravascular coagulation", "Distal amyotrophy", "Distal arthrogryposis", "Distal joint laxity", "Distal lower limb amyotrophy", "Distal lower limb muscle weakness", "Distal muscle weakness", "Distal peripheral sensory neuropathy", "Distal sensory impairment", "Distal sensory impairment of all modalities", "Distal sensory loss of all modalities", "Distal upper limb amyotrophy", "Distal upper limb muscle weakness", "Disturbance of facial expression", "Dolichocephaly", "Double aortic arch", "Down sloping shoulders", "Downslanted palpebral fissures", "Downturned corners of mouth", "Drowsiness", "Drusen", "Dry hair", "Dry skin", "Duodenal adenocarcinoma", "Duodenal atresia", "Duodenal stenosis", "Duplicated collecting system", "Duplication involving bones of the feet", "Duplication of hand bones", "Duplication of phalanx of hallux", "Duplication of the distal phalanx of hand", "Duplication of the distal phalanx of the thumb", "Duplication of thumb phalanx", "Dysarthria", "Dyscalculia", "Dyschromatopsia", "Dysdiadochokinesis", "Dysesthesia", "Dysgammaglobulinemia", "Dysgenesis of the cerebellar vermis", "Dysgenesis of the hippocampus", "Dysgerminoma", "Dysgraphia", "Dyskinesia", "Dyslexia", "Dysmenorrhea", "Dysmetria", "Dysmetric saccades", "Dysostosis multiplex", "Dyspareunia", "Dysphagia", "Dysphasia", "Dysphonia", "Dysplasia of the femoral head", "Dysplastic corpus callosum", "Dyspnea", "Dystonia", "Dystrophic fingernails", "Dystrophic toenail", "Dysuria", "Ear pain", "Early onset absence seizures", "Early onset of sexual maturation", "Easy fatigability", "Ecchymosis", "Echolalia", "Eclabion", "Eclampsia", "Ectodermal dysplasia", "Ectopia lentis", "Ectopia pupillae", "Ectopic anus", "Ectopic calcification", "Ectopic kidney", "Ectrodactyly", "Ectropion", "Ectropion of lower eyelids", "Eczema", "Eczematoid dermatitis", "Edema of the dorsum of feet", "Edema of the dorsum of hands", "Eeg with abnormally slow frequencies", "Eeg with burst suppression", "Eeg with continuous slow activity", "Eeg with focal epileptiform discharges", "Eeg with focal sharp slow waves", "Eeg with focal sharp waves", "Eeg with focal spike waves", "Eeg with focal spikes", "Eeg with frontal epileptiform discharges", "Eeg with generalized sharp slow waves", "Eeg with generalized slow activity", "Eeg with irregular generalized spike and wave complexes", "Eeg with multifocal slow activity", "Eeg with polyspike wave complexes", "Eeg with spike wave complexes", "Eeg with spike wave complexes 2 5 3 5 hz", "Elbow ankylosis", "Elbow flexion contracture", "Elevated alkaline phosphatase of bone origin", "Elevated calcitonin", "Elevated circulating alanine aminotransferase concentration", "Elevated circulating aspartate aminotransferase concentration", "Elevated circulating follicle stimulating hormone level", "Elevated circulating glutaric acid concentration", "Elevated circulating growth hormone concentration", "Elevated circulating long chain fatty acid concentration", "Elevated circulating parathyroid hormone level", "Elevated circulating thyroid stimulating hormone concentration", "Elevated creatine kinase after exercise", "Elevated diastolic blood pressure", "Elevated gamma glutamyltransferase level", "Elevated hemoglobin a1c", "Elevated hepatic transaminase", "Elevated lactate pyruvate ratio", "Elevated mean arterial pressure", "Elevated proportion of cd4 negative cd8 negative alpha beta regulatory t cells", "Elevated pulmonary artery pressure", "Elevated serum acid phosphatase", "Elevated systolic blood pressure", "Elevated tissue non specific alkaline phosphatase", "Elevated total serum tryptase", "Elevated urinary carboxylic acid", "Elevated urinary delta aminolevulinic acid", "Elevated urinary dicarboxylic acid level", "Elevated urinary monocarboxylic acid level", "Elfin facies", "Elliptocytosis", "Elongated superior cerebellar peduncle", "Embryonal neoplasm", "Embryonal renal neoplasm", "Emg abnormality", "Emg axonal abnormality", "Emg chronic denervation signs", "Emg decremental response of compound muscle action potential to repetitive nerve stimulation", "Emg impaired neuromuscular transmission", "Emg myopathic abnormalities", "Emg neuropathic changes", "Emg slow motor conduction", "Emotional lability", "Emphysema", "Enamel hypoplasia", "Encephalocele", "Encephalopathy", "Enchondroma", "Endocardial fibrosis", "Endocarditis", "Enlarged cerebellum", "Enlarged cisterna magna", "Enlarged joints", "Enlarged kidney", "Enlarged metaphyses", "Enlarged ovaries", "Enlarged posterior fossa", "Enlarged thorax", "Enlarged tonsils", "Enlargement of the costochondral junction", "Enlargement of the wrists", "Enterocolitis", "Enthesitis", "Entropion", "Enuresis", "Ependymoma", "Epicanthus", "Epicanthus inversus", "Epidermal acanthosis", "Epidermal hyperkeratosis", "Epidermal nevus", "Epidermoid cyst", "Epigastric pain", "Epileptic aura", "Epileptic encephalopathy", "Epileptic spasm", "Epiphora", "Epiphyseal dysplasia", "Epiphyseal stippling", "Epiretinal membrane", "Episodic ataxia", "Episodic hyperhidrosis", "Episodic hypertension", "Episodic pain", "Episodic respiratory distress", "Episodic tachypnea", "Episodic vomiting", "Epispadias", "Epistaxis", "Equinovarus deformity", "Equinus calcaneus", "Erectile dysfunction", "Erlenmeyer flask deformity of the femurs", "Eruption failure", "Erysipelas", "Erythema", "Erythema nodosum", "Erythematous papule", "Erythematous plaque", "Erythrocyte inclusion bodies", "Erythroderma", "Erythroid hyperplasia", "Erythroid hypoplasia", "Esodeviation", "Esophageal atresia", "Esophageal carcinoma", "Esophageal neoplasm", "Esophageal stenosis", "Esophageal stricture", "Esophageal ulceration", "Esophageal varix", "Esophagitis", "Ethylmalonic aciduria", "Eunuchoid habitus", "Euryblepharon", "Eversion of lateral third of lower eyelids", "Everted upper lip vermilion", "Exaggerated cupid s bow", "Exaggerated startle response", "Exanthem", "Excessive daytime somnolence", "Excessive salivation", "Excessive wrinkled skin", "Excessive wrinkling of palmar skin", "Exercise induced muscle cramps", "Exercise induced muscle fatigue", "Exercise induced muscle stiffness", "Exercise induced myalgia", "Exercise induced myoglobinuria", "Exercise induced rhabdomyolysis", "Exercise intolerance", "Exertional dyspnea", "Exodeviation", "Exostoses", "Expressive aphasia", "Expressive language delay", "External ear malformation", "External genital hypoplasia", "External ophthalmoplegia", "Extra axial cerebrospinal fluid accumulation", "Extrahepatic cholestasis", "Extramedullary hematopoiesis", "Extrapyramidal dyskinesia", "Extrapyramidal muscular rigidity", "Exudative retinal detachment", "Eyelid coloboma", "Eyelid myoclonus", "Facial asymmetry", "Facial capillary hemangioma", "Facial cleft", "Facial diplegia", "Facial edema", "Facial erythema", "Facial grimacing", "Facial hemangioma", "Facial hyperostosis", "Facial hypertrichosis", "Facial hypotonia", "Facial myokymia", "Facial paralysis", "Facial shape deformation", "Facial telangiectasia", "Failure of eruption of permanent teeth", "Failure to thrive", "Failure to thrive in infancy", "Fair hair", "Falls", "Fasciculations", "Fasting hyperinsulinemia", "Fasting hypoglycemia", "Fat malabsorption", "Fatigable weakness of bulbar muscles", "Fatigable weakness of distal limb muscles", "Fatigable weakness of respiratory muscles", "Fatigable weakness of skeletal muscles", "Fatigable weakness of swallowing muscles", "Fatiguable weakness of proximal limb muscles", "Fatigue", "Fatty replacement of skeletal muscle", "Feeding difficulties", "Feeding difficulties in infancy", "Female external genitalia in individual with 46 xy karyotype", "Female hypogonadism", "Female infertility", "Female reproductive system neoplasm", "Female sexual dysfunction", "Femoral bowing", "Femoral hernia", "Fetal akinesia sequence", "Fetal distress", "Fetal onset", "Fetal polyuria", "Fetal ultrasound soft marker", "Fever", "Fibroadenoma of the breast", "Fibrosarcoma", "Fibrous tissue neoplasm", "Fibular aplasia", "Fibular hypoplasia", "Fine hair", "Finger agnosia", "Finger clinodactyly", "Finger swelling", "Finger syndactyly", "Fingernail dysplasia", "Fingerprint intracellular accumulation of autofluorescent lipopigment storage material", "First degree atrioventricular block", "First dorsal interossei muscle weakness", "Flank pain", "Flared iliac wing", "Flared metaphysis", "Flared nostrils", "Flaring of rib cage", "Flat acetabular roof", "Flat cornea", "Flat face", "Flat forehead", "Flat nasal alae", "Flat occiput", "Flattened epiphysis", "Flattened femoral epiphysis", "Flattened femoral head", "Flexion contracture of digit", "Flexion contracture of thumb", "Fluctuations in consciousness", "Flushing", "Foam cells", "Focal autonomic seizure", "Focal aware seizure", "Focal cognitive seizure with deja vu jamais vu", "Focal cortical dysplasia", "Focal cortical dysplasia type ii", "Focal dystonia", "Focal emotional seizure", "Focal impaired awareness seizure", "Focal motor seizure", "Focal motor status epilepticus", "Focal myoclonic seizure", "Focal non motor seizure", "Focal onset seizure", "Focal segmental glomerulosclerosis", "Focal sensory seizure", "Focal t2 hyperintense basal ganglia lesion", "Focal t2 hyperintense brainstem lesion", "Focal tonic seizure", "Focal white matter lesions", "Follicular hyperkeratosis", "Follicular hyperplasia", "Follicular thyroid carcinoma", "Food allergy", "Food intolerance", "Foot acroosteolysis", "Foot dorsiflexor weakness", "Foot oligodactyly", "Fractures of the long bones", "Fragile nails", "Fragile skin", "Fragmented epiphyses", "Freckling", "Frequent falls", "Frontal balding", "Frontal cortical atrophy", "Frontal hirsutism", "Frontal lobe dementia", "Frontotemporal cerebral atrophy", "Frontotemporal dementia", "Full cheeks", "Fulminant hepatic failure", "Functional abnormality of male internal genitalia", "Functional abnormality of the gastrointestinal tract", "Functional abnormality of the inner ear", "Functional abnormality of the middle ear", "Functional intestinal obstruction", "Functional motor deficit", "Furrowed tongue", "Fused cervical vertebrae", "Fusion of the cerebellar hemispheres", "Gait ataxia", "Gait disturbance", "Gait imbalance", "Galactorrhea", "Gangrene", "Gastric ulcer", "Gastritis", "Gastroesophageal reflux", "Gastrointestinal atresia", "Gastrointestinal carcinoma", "Gastrointestinal hemorrhage", "Gastrointestinal infarctions", "Gastrointestinal inflammation", "Gastrointestinal obstruction", "Gastrointestinal stroma tumor", "Gastroparesis", "Gastrostomy tube feeding in infancy", "Gaze evoked nystagmus", "Generalized abnormality of skin", "Generalized aminoaciduria", "Generalized amyotrophy", "Generalized clonic seizure", "Generalized dystonia", "Generalized edema", "Generalized hirsutism", "Generalized hyperkeratosis", "Generalized hyperpigmentation", "Generalized hyperreflexia", "Generalized hypertrichosis", "Generalized hypopigmentation", "Generalized hypopigmentation of hair", "Generalized hypotonia", "Generalized joint laxity", "Generalized limb muscle atrophy", "Generalized lipodystrophy", "Generalized lymphadenopathy", "Generalized muscle weakness", "Generalized myoclonic atonic seizure", "Generalized myoclonic seizure", "Generalized neonatal hypotonia", "Generalized onset motor seizure", "Generalized onset seizure", "Generalized osteoporosis", "Generalized osteosclerosis", "Generalized tonic seizure", "Genetic anticipation", "Genital neoplasm", "Genu recurvatum", "Genu valgum", "Genu varum", "Geographic atrophy", "Germ cell neoplasia", "Germinoma", "Giant platelets", "Giant somatosensory evoked potentials", "Gingival bleeding", "Gingival fibromatosis", "Gingival overgrowth", "Gingival recession", "Gingivitis", "Glaucoma", "Glioblastoma multiforme", "Glioma", "Gliosis", "Global brain atrophy", "Glomerular deposits", "Glomerular sclerosis", "Glomerulonephritis", "Glomerulopathy", "Glomus jugular tumor", "Glossitis", "Glossoptosis", "Glucose intolerance", "Glutaric aciduria", "Glycosuria", "Goiter", "Gonadal dysgenesis", "Gonadal neoplasm", "Gonadoblastoma", "Gonadotropin deficiency", "Gonosomal inheritance", "Gout", "Gowers sign", "Grammar specific speech disorder", "Granulocytopenia", "Granulomatosis", "Gray matter heterotopia", "Gynecomastia", "Halitosis", "Hallucinations", "Hallux valgus", "Hamartoma", "Hamartoma of the eye", "Hamartoma of tongue", "Hamartomatous polyposis", "Hammertoe", "Hamstring contractures", "Hand apraxia", "Hand clenching", "Hand muscle weakness", "Hand oligodactyly", "Hand polydactyly", "Hand tremor", "Handgrip myotonia", "Happy demeanor", "Hashimoto thyroiditis", "Head banging", "Head titubation", "Head tremor", "Headache", "Heart block", "Heat intolerance", "Heinz bodies", "Hemangioblastoma", "Hemangiomatosis", "Hematemesis", "Hematological neoplasm", "Hemianopia", "Hemiatrophy", "Hemifacial spasm", "Hemihypertrophy", "Hemimegalencephaly", "Hemiparesis", "Hemiplegia hemiparesis", "Hemivertebrae", "Hemoglobinuria", "Hemolytic anemia", "Hemophagocytosis", "Hemoptysis", "Hemorrhage of the eye", "Hemothorax", "Heparan sulfate excretion in urine", "Hepatic cysts", "Hepatic encephalopathy", "Hepatic failure", "Hepatic fibrosis", "Hepatic necrosis", "Hepatitis", "Hepatoblastoma", "Hepatocellular adenoma", "Hepatocellular carcinoma", "Hepatomegaly", "Hepatosplenomegaly", "Hereditary nonpolyposis colorectal carcinoma", "Hernia", "Herpes simplex encephalitis", "Heterochromia iridis", "Heterogeneous", "Heteronymous hemianopia", "Heterophoria", "Heterotaxy", "Heterotropia", "Hiatus hernia", "High anterior hairline", "High forehead", "High frequency hearing impairment", "High frequency sensorineural hearing impairment", "High hypermetropia", "High myopia", "High narrow palate", "High palate", "High pitched voice", "Highly arched eyebrow", "Hip contracture", "Hip dislocation", "Hip dysplasia", "Hip flexor weakness", "Hip osteoarthritis", "Hip pain", "Hip subluxation", "Hirsutism", "Hoarse cry", "Hoarse voice", "Hodgkin lymphoma", "Holoprosencephaly", "Homocystinuria", "Honeycomb lung", "Horizontal eyebrow", "Horizontal nystagmus", "Horizontal pendular nystagmus", "Horizontal ribs", "Horseshoe kidney", "Humeroradial synostosis", "Hydranencephaly", "Hydrocele testis", "Hydrocephalus", "Hydrops fetalis", "Hydroureter", "Hydroxyprolinuria", "Hyperactive deep tendon reflexes", "Hyperactive patellar reflex", "Hyperactivity", "Hyperacusis", "Hyperaldosteronism", "Hyperammonemia", "Hyperautofluorescent macular lesion", "Hyperautofluorescent retinal lesion", "Hypercalcemia", "Hyperchloremic acidosis", "Hypercholesterolemia", "Hypercoagulability", "Hyperconvex fingernails", "Hyperconvex nail", "Hyperesthesia", "Hyperextensibility at wrists", "Hyperextensibility of the finger joints", "Hyperextensibility of the knee", "Hyperextensible skin", "Hypergalactosemia", "Hyperglycemia", "Hypergonadotropic hypogonadism", "Hypergranulosis", "Hyperhidrosis", "Hyperhomocystinemia", "Hyperinsulinemic hypoglycemia", "Hyperintensity of cerebral white matter on mri", "Hyperkalemia", "Hyperkeratosis", "Hyperkeratotic papule", "Hyperketonemia", "Hyperkinetic movements", "Hyperlipidemia", "Hyperlipoproteinemia", "Hyperlordosis", "Hypermagnesemia", "Hypermagnesiuria", "Hypermethioninemia", "Hypermetric saccades", "Hypermetropia", "Hypernatriuria", "Hyperorality", "Hyperostosis", "Hyperoxaluria", "Hyperparathyroidism", "Hyperphenylalaninemia", "Hyperphosphatemia", "Hyperphosphaturia", "Hyperpigmentation in sun exposed areas", "Hyperpigmentation of the fundus", "Hyperpigmentation of the skin", "Hyperpituitarism", "Hyperplasia of the maxilla", "Hyperreflexia", "Hyperreflexia in upper limbs", "Hypersomnia", "Hypersplenism", "Hypertelorism", "Hypertension associated with pheochromocytoma", "Hypertensive crisis", "Hyperthyroidism", "Hypertonia", "Hypertrichosis", "Hypertriglyceridemia", "Hypertrophic cardiomyopathy", "Hypertrophic nerve changes", "Hyperuricemia", "Hyperuricosuria", "Hyperventilation", "Hypoamylasemia", "Hypoautofluorescent retinal lesion", "Hypocalcemia", "Hypocalcemic seizures", "Hypocalcemic tetany", "Hypocalciuria", "Hypochloremia", "Hypocholesterolemia", "Hypochromia", "Hypochromic anemia", "Hypochromic microcytic anemia", "Hypodontia", "Hypoglycemic coma", "Hypoglycemic seizures", "Hypoglycorrhachia", "Hypogonadism", "Hypogonadotropic hypogonadism", "Hypohidrosis", "Hypoinsulinemia", "Hypointensity of cerebral white matter on mri", "Hypokalemia", "Hypokalemic alkalosis", "Hypokalemic metabolic alkalosis", "Hypoketotic hypoglycemia", "Hypokinesia", "Hypolipidemia", "Hypolipoproteinemia", "Hypomelanotic macule", "Hypomethioninemia", "Hypometric saccades", "Hypomimic face", "Hypoparathyroidism", "Hypophosphatemia", "Hypophosphatemic rickets", "Hypopigmentation of the fundus", "Hypopigmentation of the skin", "Hypopigmented macule", "Hypopigmented skin patches", "Hypopituitarism", "Hypoplasia of olfactory tract", "Hypoplasia of penis", "Hypoplasia of teeth", "Hypoplasia of the brainstem", "Hypoplasia of the corpus callosum", "Hypoplasia of the ear cartilage", "Hypoplasia of the epiglottis", "Hypoplasia of the femoral head", "Hypoplasia of the fovea", "Hypoplasia of the frontal lobes", "Hypoplasia of the iris", "Hypoplasia of the musculature", "Hypoplasia of the odontoid process", "Hypoplasia of the olfactory bulb", "Hypoplasia of the pons", "Hypoplasia of the radius", "Hypoplasia of the uterus", "Hypoplasia of the vagina", "Hypoplasia of the ventral pons", "Hypoplastic anemia", "Hypoplastic aortic arch", "Hypoplastic cervical vertebrae", "Hypoplastic dermoepidermal hemidesmosomes", "Hypoplastic facial bones", "Hypoplastic female external genitalia", "Hypoplastic fifth fingernail", "Hypoplastic fifth toenail", "Hypoplastic fingernail", "Hypoplastic frontal sinuses", "Hypoplastic heart", "Hypoplastic helices", "Hypoplastic hippocampus", "Hypoplastic ilia", "Hypoplastic iliac wing", "Hypoplastic iris stroma", "Hypoplastic ischia", "Hypoplastic labia majora", "Hypoplastic labia minora", "Hypoplastic nipples", "Hypoplastic pelvis", "Hypoplastic pubic rami", "Hypoplastic toenails", "Hypoplastic vertebral bodies", "Hypoproteinemia", "Hyporeflexia", "Hyporeflexia of lower limbs", "Hyporeflexia of upper limbs", "Hyposmia", "Hypotelorism", "Hypotension", "Hypothalamic gonadotropin releasing hormone deficiency", "Hypothalamic hamartoma", "Hypothalamic hypothyroidism", "Hypothermia", "Hypotriglyceridemia", "Hypouricemia", "Hypoventilation", "Hypovolemic shock", "Hypsarrhythmia", "Ichthyosis", "Ileus", "Imbalanced hemoglobin synthesis", "Immotile sperm", "Immune dysregulation", "Immunodeficiency", "Immunologic hypersensitivity", "Impacted tooth", "Impaired adp induced platelet aggregation", "Impaired antigen specific response", "Impaired collagen induced platelet aggregation", "Impaired distal proprioception", "Impaired distal tactile sensation", "Impaired distal vibration sensation", "Impaired epinephrine induced platelet aggregation", "Impaired glucose tolerance", "Impaired horizontal smooth pursuit", "Impaired mastication", "Impaired neutrophil bactericidal activity", "Impaired oropharyngeal swallow response", "Impaired pain sensation", "Impaired proprioception", "Impaired renal concentrating ability", "Impaired smooth pursuit", "Impaired social interactions", "Impaired t cell function", "Impaired tactile sensation", "Impaired tandem gait", "Impaired temperature sensation", "Impaired use of nonverbal behaviors", "Impaired vibration sensation at ankles", "Impaired vibration sensation in the lower limbs", "Impaired vibratory sensation", "Impaired visuospatial constructive cognition", "Impairment in personality functioning", "Impairment of activities of daily living", "Impotence", "Inability to walk", "Inappropriate antidiuretic hormone secretion", "Inappropriate behavior", "Inappropriate crying", "Inappropriate laughter", "Incisor macrodontia", "Incomitant strabismus", "Incomplete partition of the cochlea type ii", "Incomplete penetrance", "Incomprehensible speech", "Incoordination", "Increased adipose tissue", "Increased arm span", "Increased aspartate family amino acid level in urine", "Increased b cell count", "Increased blood pressure", "Increased blood urea nitrogen", "Increased body mass index", "Increased body weight", "Increased bone mineral density", "Increased c peptide level", "Increased cerebral lipofuscin", "Increased circulating acth level", "Increased circulating androgen concentration", "Increased circulating antibody level", "Increased circulating cortisol level", "Increased circulating gonadotropin level", "Increased circulating iga level", "Increased circulating igg level", "Increased circulating igm level", "Increased circulating interleukin 6", "Increased circulating lactate dehydrogenase concentration", "Increased circulating prolactin concentration", "Increased circulating renin level", "Increased connective tissue", "Increased csf lactate", "Increased density of long bones", "Increased endomysial connective tissue", "Increased fecal porphyrin", "Increased female libido", "Increased head circumference", "Increased hepatic glycogen content", "Increased hepatocellular lipid droplets", "Increased intracranial pressure", "Increased intramyocellular lipid droplets", "Increased laxity of ankles", "Increased ldl cholesterol concentration", "Increased level of hippuric acid in urine", "Increased level of l fucose in urine", "Increased mean corpuscular hemoglobin concentration", "Increased mean corpuscular volume", "Increased megakaryocyte count", "Increased muscle fatiguability", "Increased muscle glycogen content", "Increased muscle lipid content", "Increased nuchal translucency", "Increased overbite", "Increased proportion of cd25 mast cells", "Increased proteinogenic amino acid level in urine", "Increased sensitivity to ionizing radiation", "Increased serine family amino acid in urine", "Increased serum iron", "Increased serum lactate", "Increased serum pyruvate", "Increased serum serotonin", "Increased serum testosterone level", "Increased skull ossification", "Increased sulfur amino acid level in urine", "Increased susceptibility to fractures", "Increased theta frequency activity in eeg", "Increased total bilirubin", "Increased urinary cortisol level", "Increased urinary non proteinogenic amino acid level", "Increased urine alpha ketoglutarate concentration", "Increased urine proteinogenic amino acid derivative level", "Increased vertebral height", "Ineffective esophageal peristalsis", "Infantile axial hypotonia", "Infantile encephalopathy", "Infantile muscular hypotonia", "Infantile onset", "Infantile spasms", "Infection related seizure", "Infectious encephalitis", "Inferior lens subluxation", "Inferior vermis hypoplasia", "Infertility", "Inflammation of the large intestine", "Inflammatory abnormality of the eye", "Inflexible adherence to routines or rituals", "Inguinal freckling", "Inguinal hernia", "Insidious onset", "Insomnia", "Inspiratory stridor", "Insulin resistance", "Insulin resistant diabetes mellitus", "Intellectual disability borderline", "Intellectual disability mild", "Intellectual disability moderate", "Intellectual disability profound", "Intellectual disability progressive", "Intellectual disability severe", "Intercostal muscle weakness", "Interictal eeg abnormality", "Intermittent diarrhea", "Intermittent episodes of respiratory insufficiency due to muscle weakness", "Interphalangeal joint erosions", "Interrupted aortic arch", "Interstitial cardiac fibrosis", "Interstitial pneumonitis", "Intervertebral space narrowing", "Intestinal atresia", "Intestinal fistula", "Intestinal hypoplasia", "Intestinal malrotation", "Intestinal perforation", "Intestinal polyp", "Intestinal pseudo obstruction", "Intraalveolar phospholipid accumulation", "Intracellular accumulation of autofluorescent lipopigment storage material", "Intracranial hemorrhage", "Intracranial meningioma", "Intractable diarrhea", "Intrauterine growth retardation", "Intraventricular hemorrhage", "Intrinsic hand muscle atrophy", "Intussusception", "Inverted nipples", "Involuntary movements", "Iridocyclitis", "Iris atrophy", "Iris coloboma", "Iris hypopigmentation", "Iron accumulation in brain", "Iron accumulation in globus pallidus", "Iron deficiency anemia", "Irregular acetabular roof", "Irregular capital femoral epiphysis", "Irregular epiphyses", "Irregular femoral epiphysis", "Irregular hyperpigmentation", "Irregular iliac crest", "Irregular menstruation", "Irregular vertebral endplates", "Irritability", "Ischemic stroke", "J shaped sella turcica", "Jaundice", "Jerky head movements", "Jerky ocular pursuit movements", "Joint contracture of the 5th finger", "Joint contracture of the hand", "Joint contractures involving the joints of the feet", "Joint dislocation", "Joint hemorrhage", "Joint hyperflexibility", "Joint hypermobility", "Joint laxity", "Joint stiffness", "Joint subluxation", "Joint swelling", "Juvenile aseptic necrosis", "Juvenile cataract", "Juvenile myelomonocytic leukemia", "Juvenile onset", "Juvenile rheumatoid arthritis", "Keloids", "Keratitis", "Keratoconjunctivitis", "Keratosis pilaris", "Ketoacidosis", "Ketonuria", "Ketosis", "Ketotic hypoglycemia", "Kinetic tremor", "Kinked brainstem", "Knee clonus", "Knee dislocation", "Knee flexion contracture", "Kyphoscoliosis", "Kyphosis", "Labial hypertrophy", "Lack of insight", "Lack of peer relationships", "Lack of skin elasticity", "Lack of t cell function", "Lacrimal duct atresia", "Lacrimal duct stenosis", "Lacrimation abnormality", "Lactic acidosis", "Lacticaciduria", "Lactose intolerance", "Lagopthalmos", "Lambdoidal craniosynostosis", "Language impairment", "Large basal ganglia", "Large beaked nose", "Large earlobe", "Large face", "Large fleshy ears", "Large for gestational age", "Large foramen magnum", "Large forehead", "Large hands", "Large iliac wing", "Large intestinal polyposis", "Large placenta", "Large sella turcica", "Laryngeal cleft", "Laryngeal dystonia", "Laryngeal hypoplasia", "Laryngeal stenosis", "Laryngeal stridor", "Laryngomalacia", "Laryngotracheomalacia", "Late onset", "Lateral clavicle hook", "Leber optic atrophy", "Left atrial enlargement", "Left bundle branch block", "Left to right shunt", "Left ventricular hypertrophy", "Left ventricular noncompaction cardiomyopathy", "Left ventricular outflow tract obstruction", "Left ventricular systolic dysfunction", "Leg muscle stiffness", "Leiomyosarcoma", "Lens luxation", "Lens subluxation", "Lenticonus", "Lethal skeletal dysplasia", "Lethargy", "Leukemia", "Leukocytosis", "Leukodystrophy", "Leukoencephalopathy", "Leukonychia", "Leukopenia", "Lewy bodies", "Leydig cell neoplasia", "Lichenification", "Limb ataxia", "Limb dysmetria", "Limb dystonia", "Limb fasciculations", "Limb girdle muscle atrophy", "Limb girdle muscle weakness", "Limb girdle muscular dystrophy", "Limb hypertonia", "Limb joint contracture", "Limb muscle weakness", "Limb myoclonus", "Limb pain", "Limb tremor", "Limb undergrowth", "Limbal dermoid", "Limbal stem cell deficiency", "Limitation of joint mobility", "Limitation of knee mobility", "Limitation of movement at ankles", "Limitation of neck motion", "Limited elbow extension", "Limited elbow movement", "Limited extraocular movements", "Limited hip extension", "Limited hip movement", "Limited knee extension", "Limited wrist extension", "Limited wrist movement", "Lingual dystonia", "Lipid accumulation in hepatocytes", "Lipoatrophy", "Lipodystrophy", "Lipoma", "Lissencephaly", "Liver abscess", "Lobar holoprosencephaly", "Lobulated tongue", "Localized hirsutism", "Localized osteoporosis", "Localized skin lesion", "Long clavicles", "Long ear", "Long eyelashes", "Long fingers", "Long foot", "Long hallux", "Long neck", "Long nose", "Long palm", "Long palpebral fissure", "Long penis", "Long philtrum", "Long thorax", "Long toe", "Long tract signs", "Long upper lip", "Lop ear", "Loss of ability to walk", "Loss of consciousness", "Loss of eyelashes", "Loss of purkinje cells in the cerebellar vermis", "Loss of speech", "Loss of subcutaneous adipose tissue in limbs", "Loss of voice", "Low alkaline phosphatase", "Low anterior hairline", "Low apgar score", "Low back pain", "Low frustration tolerance", "Low grade fever", "Low hanging columella", "Low levels of vitamin d", "Low molecular weight proteinuria", "Low plasma citrulline", "Low posterior hairline", "Low self esteem", "Low set nipples", "Low set posteriorly rotated ears", "Lower extremity joint dislocation", "Lower eyelid coloboma", "Lower limb amyotrophy", "Lower limb asymmetry", "Lower limb hyperreflexia", "Lower limb hypertonia", "Lower limb metaphyseal irregularity", "Lower limb muscle weakness", "Lower limb pain", "Lower limb spasticity", "Lower limb undergrowth", "Lumbar hyperlordosis", "Lumbar kyphosis", "Lumbar scoliosis", "Lung adenocarcinoma", "Lymphangiectasis", "Lymphangioma", "Lymphedema", "Lymphocytosis", "Lymphoma", "Lymphopenia", "Lymphoproliferative disorder", "Macrocephaly at birth", "Macrocytic anemia", "Macrodactyly", "Macrodontia", "Macrodontia of permanent maxillary central incisor", "Macroglossia", "Macrogyria", "Macroorchidism", "Macroscopic hematuria", "Macrotia", "Macrovesicular hepatic steatosis", "Macular atrophy", "Macular coloboma", "Macular degeneration", "Macular dystrophy", "Macular hyperpigmentation", "Macular hypoplasia", "Macular purpura", "Macular thickening", "Macule", "Malabsorption", "Malar prominence", "Malar rash", "Male hypogonadism", "Male infertility", "Male pseudohermaphroditism", "Male reproductive system neoplasm", "Male sexual dysfunction", "Malignant genitourinary tract tumor", "Malignant hyperthermia", "Malignant neoplasm of the central nervous system", "Malnutrition", "Malrotation of small bowel", "Mandibular aplasia", "Mandibular prognathia", "Mania", "Mask like facies", "Mastoiditis", "Maternal diabetes", "Maternal hypertension", "Maturity onset diabetes of the young", "Meconium stained amniotic fluid", "Medial flaring of the eyebrow", "Median cleft lip", "Median cleft palate", "Mediastinal lymphadenopathy", "Medullary nephrocalcinosis", "Medulloblastoma", "Megalencephaly", "Megaloblastic anemia", "Megalocornea", "Melanocytic nevus", "Melanoma", "Melena", "Membranoproliferative glomerulonephritis", "Memory impairment", "Meningioma", "Meningitis", "Meningocele", "Meningoencephalocele", "Menorrhagia", "Mental deterioration", "Mesoaxial hand polydactyly", "Mesoaxial polydactyly", "Mesomelia", "Metabolic acidosis", "Metabolic alkalosis", "Metacarpophalangeal joint contracture", "Metamorphopsia", "Metaphyseal chondrodysplasia", "Metaphyseal cupping", "Metaphyseal dysplasia", "Metaphyseal irregularity", "Metaphyseal sclerosis", "Metaphyseal spurs", "Metaphyseal striations", "Metaphyseal widening", "Metatarsal synostosis", "Metatarsus adductus", "Metatarsus valgus", "Methemoglobinemia", "Methylmalonic acidemia", "Methylmalonic aciduria", "Metopic synostosis", "Metrorrhagia", "Microcornea", "Microcytic anemia", "Microdontia", "Microglossia", "Micrographia", "Micromelia", "Micronodular cirrhosis", "Micropenis", "Microphallus", "Microretrognathia", "Microscopic hematuria", "Microtia third degree", "Microvesicular hepatic steatosis", "Middle age onset", "Midface retrusion", "Midline defect of the nose", "Migraine", "Mild global developmental delay", "Mild hearing impairment", "Mild microcephaly", "Mild postnatal growth retardation", "Mild short stature", "Mildly elevated creatine kinase", "Milia", "Minicore myopathy", "Minimal change glomerulonephritis", "Misalignment of incisors", "Missing ribs", "Mitochondrial inheritance", "Mitochondrial myopathy", "Mitochondrial respiratory chain defects", "Mitral stenosis", "Mitral valve calcification", "Mitral valve prolapse", "Mitten deformity", "Mixed demyelinating and axonal polyneuropathy", "Mixed hearing impairment", "Mixed hypo and hyperpigmentation of the skin", "Moderate albuminuria", "Moderate global developmental delay", "Moderate sensorineural hearing impairment", "Moderately reduced visual acuity", "Molar tooth sign on mri", "Molluscoid pseudotumors", "Molluscum contagiosum", "Monochromacy", "Monocytosis", "Monotonic speech", "Mood swings", "Morning glory anomaly", "Morning myoclonic jerks", "Morphological abnormality of the corticospinal tract", "Morphological abnormality of the middle ear", "Morphological abnormality of the pyramidal tract", "Morphological abnormality of the vestibule of the inner ear", "Mortality aging", "Motor axonal neuropathy", "Motor delay", "Motor deterioration", "Motor neuron atrophy", "Motor polyneuropathy", "Motor regression", "Motor seizure", "Motor tics", "Mottled pigmentation", "Movement abnormality of the tongue", "Moyamoya phenomenon", "Mucosal telangiectasiae", "Multicystic kidney dysplasia", "Multifactorial inheritance", "Multifocal cerebral white matter abnormalities", "Multifocal epileptiform discharges", "Multifocal seizures", "Multiple cafe au lait spots", "Multiple enchondromatosis", "Multiple exostoses", "Multiple gastric polyps", "Multiple glomerular cysts", "Multiple impacted teeth", "Multiple joint contractures", "Multiple joint dislocation", "Multiple lentigines", "Multiple lipomas", "Multiple mitochondrial dna deletions", "Multiple myeloma", "Multiple prenatal fractures", "Multiple renal cysts", "Multiple rib fractures", "Multiple rows of eyelashes", "Multiple suture craniosynostosis", "Muscle abnormality related to mitochondrial dysfunction", "Muscle fiber atrophy", "Muscle fiber inclusion bodies", "Muscle fiber necrosis", "Muscle fiber splitting", "Muscle fiber tubular inclusions", "Muscle fibrillation", "Muscle flaccidity", "Muscle hypertrophy of the lower extremities", "Muscle spasm", "Muscle stiffness", "Muscle weakness", "Muscular dystrophy", "Muscular hypotonia of the trunk", "Muscular ventricular septal defect", "Mutism", "Myalgia", "Mydriasis", "Myelodysplasia", "Myelofibrosis", "Myeloid leukemia", "Myelomeningocele", "Myelopathy", "Myeloproliferative disorder", "Myocardial fibrosis", "Myoclonic absence seizure", "Myoclonic seizure", "Myoclonic spasms", "Myoclonus", "Myofibrillar myopathy", "Myoglobinuria", "Myokymia", "Myopathic facies", "Myopathy", "Myopia", "Myositis", "Myotonia", "Naevus flammeus of the eyelid", "Nail dysplasia", "Nail dystrophy", "Nail pits", "Narrow face", "Narrow foot", "Narrow foramen obturatorium", "Narrow forehead", "Narrow iliac wing", "Narrow internal auditory canal", "Narrow jaw", "Narrow mouth", "Narrow nasal bridge", "Narrow nasal ridge", "Narrow nose", "Narrow palate", "Narrow palm", "Narrow palpebral fissure", "Narrow pelvis bone", "Narrow vertebral interpedicular distance", "Nasal congestion", "Nasal regurgitation", "Nasal speech", "Nasogastric tube feeding", "Nasogastric tube feeding in infancy", "Nasolacrimal duct obstruction", "Natal tooth", "Nausea", "Nausea and vomiting", "Neck flexor weakness", "Neck muscle weakness", "Negativism", "Nemaline bodies", "Neonatal alloimmune thrombocytopenia", "Neonatal asphyxia", "Neonatal breathing dysregulation", "Neonatal death", "Neonatal hyperbilirubinemia", "Neonatal hypoglycemia", "Neonatal hypotonia", "Neonatal insulin dependent diabetes mellitus", "Neonatal onset", "Neonatal respiratory distress", "Neoplasm", "Neoplasm by histology", "Neoplasm of fatty tissue", "Neoplasm of head and neck", "Neoplasm of striated muscle", "Neoplasm of the adrenal cortex", "Neoplasm of the adrenal gland", "Neoplasm of the breast", "Neoplasm of the colon", "Neoplasm of the ear", "Neoplasm of the endocrine system", "Neoplasm of the eye", "Neoplasm of the gallbladder", "Neoplasm of the gastrointestinal tract", "Neoplasm of the genitourinary tract", "Neoplasm of the heart", "Neoplasm of the inner ear", "Neoplasm of the large intestine", "Neoplasm of the larynx", "Neoplasm of the liver", "Neoplasm of the male external genitalia", "Neoplasm of the middle ear", "Neoplasm of the nervous system", "Neoplasm of the oral cavity", "Neoplasm of the pancreas", "Neoplasm of the parathyroid gland", "Neoplasm of the peripheral nervous system", "Neoplasm of the pituitary gland", "Neoplasm of the rectum", "Neoplasm of the respiratory system", "Neoplasm of the skeletal system", "Neoplasm of the skin", "Neoplasm of the small intestine", "Neoplasm of the stomach", "Neoplasm of the thymus", "Neoplasm of the thyroid gland", "Neoplasm of the tongue", "Neoplasm of the tracheobronchial system", "Nephritis", "Nephrocalcinosis", "Nephrogenic diabetes insipidus", "Nephrolithiasis", "Nephronophthisis", "Nephropathy", "Nephrotic syndrome", "Neuralgia", "Neurodegeneration", "Neuroendocrine neoplasm", "Neurofibrillary tangles", "Neurofibromas", "Neurogenic bladder", "Neuroinflammation", "Neuromuscular dysphagia", "Neuronal loss in basal ganglia", "Neuronal loss in central nervous system", "Neuronal loss in the cerebral cortex", "Neuropathic arthropathy", "Neutropenia in presence of anti neutropil antibodies", "Neutrophilia", "Nevus", "Night sweats", "No social interaction", "Nocturia", "Nocturnal hypoventilation", "Nocturnal seizures", "Nodular goiter", "Non hodgkin lymphoma", "Non midline cleft lip", "Non midline cleft palate", "Non motor seizure", "Non obstructive azoospermia", "Noncompaction cardiomyopathy", "Nonimmune hydrops fetalis", "Nonketotic hypoglycemia", "Nonprogressive", "Nonprogressive cerebellar ataxia", "Nonprogressive encephalopathy", "Nonspherocytic hemolytic anemia", "Normochromic anemia", "Normocytic anemia", "Nuclear cataract", "Numerous nevi", "Numerous pigmented freckles", "Nyctalopia", "Nystagmus induced head nodding", "Obsessive compulsive behavior", "Obsessive compulsive trait", "Obstructive sleep apnea", "Occipital cortical atrophy", "Occipital encephalocele", "Occipital meningocele", "Ocular albinism", "Ocular anterior segment dysgenesis", "Ocular pain", "Oculogyric crisis", "Oculomotor apraxia", "Oculomotor nerve palsy", "Odontogenic neoplasm", "Oligoarthritis", "Oligodactyly", "Oligodontia", "Oligohydramnios", "Oligomenorrhea", "Oligosacchariduria", "Oligospermia", "Oliguria", "Olivopontocerebellar atrophy", "Olivopontocerebellar hypoplasia", "Omphalocele", "Onion bulb formation", "Onset", "Onychogryposis", "Onychogryposis of toenails", "Onycholysis", "Onychomycosis", "Open angle glaucoma", "Open bite", "Open mouth", "Open operculum", "Ophthalmoparesis", "Opisthotonus", "Opportunistic infection", "Opsoclonus", "Optic atrophy", "Optic disc coloboma", "Optic disc hypoplasia", "Optic disc pallor", "Optic nerve compression", "Optic nerve dysplasia", "Optic nerve hypoplasia", "Optic neuropathy", "Oral aversion", "Oral cavity bleeding", "Oral cleft", "Oral leukoplakia", "Oral mucosal blisters", "Oral pharyngeal dysphagia", "Oral ulcer", "Orchitis", "Organic aciduria", "Orofacial dyskinesia", "Oromandibular dystonia", "Oromotor apraxia", "Oroticaciduria", "Orthokeratosis", "Orthopnea", "Orthostatic hypotension", "Orthostatic hypotension due to autonomic dysfunction", "Osteoarthritis", "Osteochondroma", "Osteochondrosis", "Osteolysis", "Osteolysis involving bones of the feet", "Osteolysis involving bones of the upper limbs", "Osteolytic defects of the distal phalanges of the hand", "Osteomalacia", "Osteomyelitis", "Osteopenia", "Osteopetrosis", "Osteoporosis", "Osteosarcoma", "Otitis media", "Otosclerosis", "Oval face", "Ovarian carcinoma", "Ovarian cyst", "Ovarian gonadoblastoma", "Ovarian neoplasm", "Ovarian papillary adenocarcinoma", "Overfolding of the superior helices", "Overfriendliness", "Overgrowth", "Overhanging nasal tip", "Overlapping fingers", "Overlapping toe", "Overriding aorta", "Overtubulated long bones", "Overweight", "Ovoid vertebral bodies", "Ovotestis", "Oxycephaly", "Pace of progression", "Pain", "Pain in head and neck region", "Pain insensitivity", "Painless fractures due to injury", "Pallor", "Palmar hyperhidrosis", "Palmar pits", "Palmar telangiectasia", "Palmoplantar blistering", "Palmoplantar cutis laxa", "Palmoplantar hyperhidrosis", "Palpebral edema", "Palpitations", "Pancreatic adenocarcinoma", "Pancreatic cysts", "Pancreatic fibrosis", "Pancreatic hypoplasia", "Pancreatic islet cell hyperplasia", "Pancreatitis", "Pancytopenia", "Panhypogammaglobulinemia", "Panhypopituitarism", "Panniculitis", "Papillary renal cell carcinoma", "Papillary thyroid carcinoma", "Papilledema", "Papilloma", "Papule", "Paracentral scotoma", "Paraganglioma", "Parakeratosis", "Paralysis", "Paranoia", "Paraparesis", "Paraplegia", "Paraplegia paraparesis", "Parasomnia", "Parathyroid adenoma", "Parathyroid carcinoma", "Parathyroid dysgenesis", "Paresthesia", "Parietal bossing", "Parietal cortical atrophy", "Parietal foramina", "Parkinsonism", "Parkinsonism with favorable response to dopaminergic medication", "Paronychia", "Paroxysmal bursts of laughter", "Paroxysmal dyskinesia", "Paroxysmal dystonia", "Paroxysmal involuntary eye movements", "Paroxysmal ventricular tachycardia", "Partial agenesis of the corpus callosum", "Partial albinism", "Partial anomalous pulmonary venous return", "Partial duplication of the distal phalanges of the hand", "Partial duplication of the phalanx of hand", "Patchy alopecia", "Patchy changes of bone mineral density", "Patchy hypopigmentation of hair", "Patchy palmoplantar hyperkeratosis", "Patellar aplasia", "Patellar dislocation", "Patellar hypoplasia", "Patellar subluxation", "Patent ductus arteriosus", "Patent foramen ovale", "Pathologic fracture", "Pectus carinatum", "Pectus excavatum", "Pectus excavatum of inferior sternum", "Pedal edema", "Pediatric onset", "Pelvic girdle muscle weakness", "Pelvic kidney", "Pendular nystagmus", "Penetrating foot ulcers", "Peptic ulcer", "Percussion myotonia", "Perianal abscess", "Periauricular skin pits", "Pericardial effusion", "Pericarditis", "Perifoveal ring of hyperautofluorescence", "Perimembranous ventricular septal defect", "Perineal fistula", "Periodic paralysis", "Periodontitis", "Periorbital edema", "Periorbital fullness", "Peripheral arterial stenosis", "Peripheral axonal degeneration", "Peripheral axonal neuropathy", "Peripheral cyanosis", "Peripheral demyelination", "Peripheral edema", "Peripheral hypermyelination", "Peripheral hypomyelination", "Peripheral neuropathy", "Peripheral opacification of the cornea", "Peripheral pulmonary artery stenosis", "Peripheral retinal avascularization", "Peripheral visual field loss", "Periportal fibrosis", "Perisylvian polymicrogyria", "Peritoneal abscess", "Peritonitis", "Periventricular cysts", "Periventricular heterotopia", "Periventricular leukomalacia", "Periventricular nodular heterotopia", "Periventricular white matter hyperintensities", "Peroneal muscle atrophy", "Perseveration", "Persistence of hemoglobin f", "Persistence of primary teeth", "Persistent bleeding after trauma", "Persistent ebv viremia", "Persistent head lag", "Personality changes", "Personality disorder", "Pes cavus", "Pes planus", "Pes valgus", "Petechiae", "Peters anomaly", "Phalangeal dislocation", "Pharyngitis", "Phenotypic variability", "Pheochromocytoma", "Phimosis", "Phocomelia", "Phonophobia", "Photophobia", "Photopsia", "Photoreceptor layer loss on macular oct", "Phthisis bulbi", "Physical urticaria", "Pierre robin sequence", "Pigmentary retinopathy", "Pili canaliculi", "Pili torti", "Pilomatrixoma", "Pineal cyst", "Pituitary adenoma", "Pituitary growth hormone cell adenoma", "Pituitary hypothyroidism", "Pituitary prolactin cell adenoma", "Plagiocephaly", "Plantar hyperkeratosis", "Platybasia", "Platyspondyly", "Pleural effusion", "Pleuritis", "Pneumonia", "Pneumothorax", "Poikilocytosis", "Poikiloderma", "Pointed chin", "Polar cataract", "Pollakisuria", "Polyarticular arthropathy", "Polyclonal elevation of igm", "Polycystic kidney dysplasia", "Polycystic liver disease", "Polycythemia", "Polydactyly", "Polygenic inheritance", "Polyhydramnios", "Polymicrogyria", "Polyneuropathy", "Polyphagia", "Polysplenia", "Polyuria", "Pontocerebellar atrophy", "Poor appetite", "Poor coordination", "Poor eye contact", "Poor fine motor coordination", "Poor gross motor coordination", "Poor head control", "Poor motor coordination", "Poor speech", "Poor suck", "Poor wound healing", "Popliteal pterygium", "Porencephalic cyst", "Porokeratosis", "Porphyrinuria", "Portal fibrosis", "Portal vein thrombosis", "Positional foot deformity", "Positive romberg sign", "Post partum hemorrhage", "Postaxial foot polydactyly", "Postaxial hand polydactyly", "Postaxial polydactyly", "Posterior blepharitis", "Posterior embryotoxon", "Posterior fossa cyst", "Posterior pharyngeal cleft", "Posterior pituitary dysgenesis", "Posterior polar cataract", "Posterior subcapsular cataract", "Posteriorly rotated ears", "Postexertional malaise", "Postnatal growth retardation", "Postural instability", "Postural tremor", "Potter facies", "Preauricular skin tag", "Preaxial foot polydactyly", "Preaxial hand polydactyly", "Preaxial polydactyly", "Precocious atherosclerosis", "Predominantly lower limb lymphedema", "Prelingual sensorineural hearing impairment", "Premature adrenarche", "Premature arteriosclerosis", "Premature birth", "Premature coronary artery atherosclerosis", "Premature graying of hair", "Premature loss of primary teeth", "Premature loss of teeth", "Premature osteoarthritis", "Premature ovarian insufficiency", "Premature pubarche", "Premature rupture of membranes", "Premature skin wrinkling", "Premature thelarche", "Premature ventricular contraction", "Prematurely aged appearance", "Prenatal maternal abnormality", "Prenatal movement abnormality", "Primary adrenal insufficiency", "Primary amenorrhea", "Primary congenital glaucoma", "Primary gonadal insufficiency", "Primary hypercortisolism", "Primary hyperparathyroidism", "Primary microcephaly", "Primary peritoneal carcinoma", "Primitive neuroectodermal tumor", "Primitive reflex", "Productive cough", "Profound global developmental delay", "Profound hearing impairment", "Profound sensorineural hearing impairment", "Progeroid facial appearance", "Progressive", "Progressive cerebellar ataxia", "Progressive distal muscle weakness", "Progressive encephalopathy", "Progressive external ophthalmoplegia", "Progressive extrapyramidal movement disorder", "Progressive flexion contractures", "Progressive gait ataxia", "Progressive hearing impairment", "Progressive inability to walk", "Progressive leukoencephalopathy", "Progressive macrocephaly", "Progressive microcephaly", "Progressive muscle weakness", "Progressive neurologic deterioration", "Progressive night blindness", "Progressive peripheral neuropathy", "Progressive pes cavus", "Progressive proximal muscle weakness", "Progressive psychomotor deterioration", "Progressive pulmonary function impairment", "Progressive sensorineural hearing impairment", "Progressive spastic paraparesis", "Progressive spastic paraplegia", "Progressive spastic quadriplegia", "Progressive spasticity", "Progressive visual field defects", "Progressive visual loss", "Prolinuria", "Prolonged bleeding after dental extraction", "Prolonged bleeding after surgery", "Prolonged bleeding following circumcision", "Prolonged bleeding following procedure", "Prolonged bleeding time", "Prolonged neonatal jaundice", "Prolonged partial thromboplastin time", "Prolonged qtc interval", "Prominent antihelix", "Prominent antitragus", "Prominent calcaneus", "Prominent crus of helix", "Prominent digit pad", "Prominent ear helix", "Prominent eyelashes", "Prominent forehead", "Prominent metopic ridge", "Prominent nasal bridge", "Prominent nasal tip", "Prominent nasolabial fold", "Prominent nose", "Prominent occiput", "Prominent sternum", "Prominent superficial blood vessels", "Prominent supraorbital ridges", "Prominent umbilicus", "Prominent veins on trunk", "Proportionate short stature", "Proportionate tall stature", "Proptosis", "Prostate neoplasm", "Protein avoidance", "Protein losing enteropathy", "Protracted diarrhea", "Protruding ear", "Protruding tongue", "Protrusio acetabuli", "Protuberant abdomen", "Proximal amyotrophy", "Proximal femoral epiphysiolysis", "Proximal femoral metaphyseal abnormality", "Proximal femoral metaphyseal irregularity", "Proximal muscle weakness", "Proximal muscle weakness in lower limbs", "Proximal muscle weakness in upper limbs", "Proximal renal tubular acidosis", "Proximal symphalangism", "Proximal tubulopathy", "Proximal upper limb amyotrophy", "Pruritus", "Pseudoarthrosis", "Pseudobulbar paralysis", "Pseudobulbar signs", "Pseudoepiphyses", "Pseudoepiphyses of hand bones", "Pseudoepiphyses of the metacarpals", "Pseudohypoaldosteronism", "Pseudohypoparathyroidism", "Psoriasiform dermatitis", "Psychic epileptic aura", "Psychogenic non epileptic seizure", "Psychomotor deterioration", "Psychomotor retardation", "Psychosis", "Psychotic episodes", "Psychotic mentation", "Pterygium", "Ptosis", "Puberty and gonadal disorders", "Pulmonary artery atresia", "Pulmonary artery dilatation", "Pulmonary artery hypoplasia", "Pulmonary artery stenosis", "Pulmonary carcinoid tumor", "Pulmonary cyst", "Pulmonary edema", "Pulmonary embolism", "Pulmonary fibrosis", "Pulmonary hemorrhage", "Pulmonary hypoplasia", "Pulmonary infiltrates", "Pulmonary insufficiency", "Pulmonary interstitial high resolution computed tomography abnormality", "Pulmonary venous hypertension", "Pulmonic stenosis", "Pulverulent cataract", "Punctate cataract", "Punctate opacification of the cornea", "Pure red cell aplasia", "Purpura", "Pustule", "Pyelonephritis", "Pyoderma gangrenosum", "Pyridoxine responsive sideroblastic anemia", "Quadriceps muscle weakness", "Radial bowing", "Radial deviation of the 2nd finger", "Radial deviation of the hand", "Radial deviation of the hand or of fingers of the hand", "Radioulnar dislocation", "Radioulnar synostosis", "Ragged red muscle fibers", "Rapidly progressive", "Raynaud phenomenon", "Reactive hypoglycemia", "Receptive language delay", "Rectal abscess", "Rectal fistula", "Rectal prolapse", "Recurrent", "Recurrent abscess formation", "Recurrent acute respiratory tract infection", "Recurrent aspergillus infections", "Recurrent aspiration pneumonia", "Recurrent bacterial infections", "Recurrent bacterial skin infections", "Recurrent bronchitis", "Recurrent bronchopulmonary infections", "Recurrent corneal erosions", "Recurrent cutaneous abscess formation", "Recurrent ear infections", "Recurrent fever", "Recurrent fractures", "Recurrent gastroenteritis", "Recurrent hand flapping", "Recurrent herpes", "Recurrent hypoglycemia", "Recurrent infection of the gastrointestinal tract", "Recurrent joint dislocation", "Recurrent lower respiratory tract infections", "Recurrent mycobacterial infections", "Recurrent opportunistic infections", "Recurrent otitis media", "Recurrent pancreatitis", "Recurrent paroxysmal headache", "Recurrent pharyngitis", "Recurrent pneumonia", "Recurrent respiratory infections", "Recurrent sinopulmonary infections", "Recurrent sinusitis", "Recurrent skin infections", "Recurrent staphylococcal infections", "Recurrent staphylococcus aureus infections", "Recurrent tonsillitis", "Recurrent upper and lower respiratory tract infections", "Recurrent urinary tract infections", "Recurrent viral infections", "Red eye", "Red green dyschromatopsia", "Red hair", "Reduced antigen specific t cell proliferation", "Reduced antithrombin iii activity", "Reduced brain n acetyl aspartate level by mrs", "Reduced c peptide level", "Reduced circulating prolactin concentration", "Reduced consciousness confusion", "Reduced delayed hypersensitivity", "Reduced factor viii activity", "Reduced factor xi activity", "Reduced factor xii activity", "Reduced factor xiii activity", "Reduced forced expiratory volume in one second", "Reduced forced vital capacity", "Reduced natural killer cell count", "Reduced pancreatic beta cells", "Reduced protein c activity", "Reduced protein s activity", "Reduced renal corticomedullary differentiation", "Reduced sperm motility", "Reduced subcutaneous adipose tissue", "Reduced systolic function", "Reduced tendon reflexes", "Reduced visual acuity", "Reduced vital capacity", "Reduction of neutrophil motility", "Redundant neck skin", "Redundant skin", "Refractory anemia", "Regional abnormality of skin", "Relative macrocephaly", "Remnants of the hyaloid vascular system", "Renal agenesis", "Renal cell carcinoma", "Renal cortical cysts", "Renal cortical microcysts", "Renal corticomedullary cysts", "Renal cyst", "Renal duplication", "Renal dysplasia", "Renal fanconi syndrome", "Renal fibrosis", "Renal hamartoma", "Renal hypoplasia", "Renal hypoplasia aplasia", "Renal insufficiency", "Renal magnesium wasting", "Renal malrotation", "Renal phosphate wasting", "Renal potassium wasting", "Renal salt wasting", "Renal steatosis", "Renal tubular acidosis", "Renal tubular atrophy", "Renal tubular dysfunction", "Renal tubular epithelial necrosis", "Renovascular hypertension", "Repetitive compulsive behavior", "Respiratory alkalosis", "Respiratory arrest", "Respiratory distress", "Respiratory failure", "Respiratory failure requiring assisted ventilation", "Respiratory insufficiency", "Respiratory insufficiency due to defective ciliary clearance", "Respiratory paralysis", "Respiratory tract infection", "Response to drugs acting on neuromuscular transmission", "Resting tremor", "Restless legs", "Restlessness", "Restrictive behavior", "Restrictive cardiomyopathy", "Restrictive ventilatory defect", "Reticular hyperpigmentation", "Reticulated skin pigmentation", "Reticulocytopenia", "Reticulocytosis", "Retinal arterial tortuosity", "Retinal arteriolar tortuosity", "Retinal atrophy", "Retinal coloboma", "Retinal degeneration", "Retinal detachment", "Retinal dysplasia", "Retinal dystrophy", "Retinal fold", "Retinal hamartoma", "Retinal hemorrhage", "Retinal neovascularization", "Retinal nonattachment", "Retinal perforation", "Retinal pigment epithelial atrophy", "Retinal pigment epithelial mottling", "Retinal telangiectasia", "Retinal thinning", "Retinal vascular tortuosity", "Retinopathy", "Retrocollis", "Retrognathia", "Rhabdomyolysis", "Rhabdomyosarcoma", "Rhegmatogenous retinal detachment", "Rheumatoid arthritis", "Rheumatoid factor positive", "Rhinitis", "Rhizomelia", "Rhizomelic arm shortening", "Rib fusion", "Rib segmentation abnormalities", "Rickets", "Ridged nail", "Rieger anomaly", "Right aortic arch with mirror image branching", "Right bundle branch block", "Right ventricular cardiomyopathy", "Right ventricular dilatation", "Right ventricular hypertrophy", "Rigidity", "Rimmed vacuoles", "Rod cone dystrophy", "Rotary nystagmus", "Round ear", "Round face", "Saccadic oscillation", "Saccadic smooth pursuit", "Sacrococcygeal teratoma", "Sagittal craniosynostosis", "Sandal gap", "Sarcoma", "Scaling skin", "Scanning speech", "Scaphocephaly", "Scapular winging", "Scarring", "Scarring alopecia of scalp", "Schistocytosis", "Schizencephaly", "Schizophrenia", "Schwannoma", "Scleral staphyloma", "Sclerocornea", "Scleroderma", "Sclerosis of hand bone", "Sclerosis of skull base", "Sclerotic vertebral endplates", "Scotoma", "Scrotal hypoplasia", "Sea blue histiocytosis", "Seborrheic dermatitis", "Second degree atrioventricular block", "Secondary amenorrhea", "Secondary growth hormone deficiency", "Secondary microcephaly", "Secretory diarrhea", "Secundum atrial septal defect", "Segmental peripheral demyelination remyelination", "Selective tooth agenesis", "Self injurious behavior", "Self mutilation", "Semilobar holoprosencephaly", "Senile plaques", "Sensorimotor neuropathy", "Sensory ataxia", "Sensory axonal neuropathy", "Sensory neuropathy", "Sepsis", "Septate vagina", "Septic arthritis", "Septo optic dysplasia", "Serositis", "Severe b lymphocytopenia", "Severe combined immunodeficiency", "Severe cytomegalovirus infection", "Severe demyelination of the white matter", "Severe expressive language delay", "Severe failure to thrive", "Severe global developmental delay", "Severe hearing impairment", "Severe infection", "Severe intrauterine growth retardation", "Severe lactic acidosis", "Severe muscular hypotonia", "Severe photosensitivity", "Severe postnatal growth retardation", "Severe short limb dwarfism", "Severe short stature", "Severe varicella zoster infection", "Severe viral infection", "Severely reduced visual acuity", "Shagreen patch", "Shallow acetabular fossae", "Shallow anterior chamber", "Shallow orbits", "Shawl scrotum", "Shield chest", "Shock", "Short 1st metacarpal", "Short attention span", "Short chin", "Short clavicles", "Short columella", "Short digit", "Short face", "Short femur", "Short foot", "Short fourth metatarsal", "Short lingual frenulum", "Short long bone", "Short lower limbs", "Short middle phalanx of finger", "Short nail", "Short nose", "Short palm", "Short palpebral fissure", "Short phalanx of the thumb", "Short philtrum", "Short proximal phalanx of finger", "Short ribs", "Short stepped shuffling gait", "Short sternum", "Short term memory impairment", "Short thorax", "Short thumb", "Short tibia", "Short umbilical cord", "Short upper lip", "Shortened pr interval", "Shortened qt interval", "Shortening of all distal phalanges of the fingers", "Shortening of all middle phalanges of the fingers", "Shoulder dislocation", "Shoulder girdle muscle atrophy", "Shoulder girdle muscle weakness", "Shoulder pain", "Shuffling gait", "Shyness", "Sideroblastic anemia", "Simple ear", "Simple febrile seizure", "Simplified gyral pattern", "Single fiber emg abnormality", "Single naris", "Single transverse palmar crease", "Single ventricle", "Sinus bradycardia", "Sinus tachycardia", "Sirenomelia", "Skeletal dysplasia", "Skeletal muscle atrophy", "Skeletal muscle hypertrophy", "Skeletal myopathy", "Skin appendage neoplasm", "Skin dimple", "Skin erosion", "Skin nodule", "Skin picking", "Skin pit", "Skin plaque", "Skin rash", "Skin tags", "Skin ulcer", "Skin vesicle", "Skull asymmetry", "Slanting of the palpebral fissure", "Sleep apnea", "Sleep disturbance", "Sleep wake cycle disturbance", "Slender build", "Slender finger", "Slender long bone", "Slender toe", "Sloping forehead", "Slow decrease in visual acuity", "Slow pupillary light response", "Slow saccadic eye movements", "Slowly progressive", "Slurred speech", "Small anterior fontanelle", "Small basal ganglia", "Small cerebral cortex", "Small earlobe", "Small epiphyses", "Small face", "Small for gestational age", "Small hand", "Small intestinal dysmotility", "Small nail", "Small pituitary gland", "Small placenta", "Smooth muscle antibody positivity", "Smooth philtrum", "Snoring", "Social and occupational deterioration", "Soft doughy skin", "Soft skin", "Soft tissue sarcoma", "Solitary median maxillary central incisor", "Somatic mosaicism", "Somatic mutation", "Somatic sensory dysfunction", "Sound sensitivity", "Sparse and thin eyebrow", "Sparse body hair", "Sparse eyebrow", "Sparse eyelashes", "Sparse hair", "Sparse lateral eyebrow", "Sparse or absent eyelashes", "Sparse scalp hair", "Spastic ataxia", "Spastic diplegia", "Spastic dysarthria", "Spastic gait", "Spastic hyperactive bladder", "Spastic paraparesis", "Spastic paraparetic gait", "Spastic paraplegia", "Spastic tetraparesis", "Spastic tetraplegia", "Spasticity", "Specific learning disability", "Speech apraxia", "Speech articulation difficulties", "Spider hemangioma", "Spina bifida", "Spina bifida occulta", "Spinal canal stenosis", "Spinal cord compression", "Spinal cord lesion", "Spinal cord tumor", "Spinal deformities", "Spinal muscular atrophy", "Spinal rigidity", "Spinocerebellar tract degeneration", "Splanchnic vein thrombosis", "Splenomegaly", "Split nail", "Spoken word recognition deficit", "Spondyloepimetaphyseal dysplasia", "Spondyloepiphyseal dysplasia", "Spondylolisthesis", "Spondylolysis", "Spontaneous abortion", "Spontaneous hematomas", "Spontaneous hemolytic crises", "Spontaneous pain sensation", "Spontaneous recurrent epistaxis", "Sporadic", "Spotty hyperpigmentation", "Spotty hypopigmentation", "Sprengel anomaly", "Squamous cell carcinoma", "Squamous cell carcinoma of the skin", "Square face", "Squared iliac bones", "St segment elevation", "Stage 5 chronic kidney disease", "Staring gaze", "Status epilepticus", "Status epilepticus with prominent motor symptoms", "Stenosis of the external auditory canal", "Steppage gait", "Stereotypical hand wringing", "Stereotypy", "Steroid resistant nephrotic syndrome", "Stiff skin", "Stillbirth", "Stomach cancer", "Stomatitis", "Stomatocytosis", "Stooped posture", "Streak ovary", "Striae distensae", "Stridor", "Stroke", "Stroke like episode", "Stuttering", "Subacute progressive viral hepatitis", "Subarachnoid hemorrhage", "Subcapsular cataract", "Subcortical band heterotopia", "Subcortical cerebral atrophy", "Subcortical heterotopia", "Subcutaneous hemorrhage", "Subcutaneous lipoma", "Subcutaneous nodule", "Subdural hemorrhage", "Subependymal cysts", "Subglottic stenosis", "Submucous cleft of soft and hard palate", "Submucous cleft soft palate", "Subretinal fluid", "Subsarcolemmal accumulations of abnormally shaped mitochondria", "Substantia nigra gliosis", "Subvalvular aortic stenosis", "Sudden death", "Sudden episodic apnea", "Sudden loss of visual acuity", "Suicidal ideation", "Sunken cheeks", "Supernumerary bones of the axial skeleton", "Supernumerary nipple", "Supernumerary spleens", "Supernumerary tooth", "Supranuclear gaze palsy", "Supranuclear ophthalmoplegia", "Supravalvular aortic stenosis", "Supraventricular arrhythmia", "Supraventricular tachycardia", "Swan neck like deformities of the fingers", "Symphalangism affecting the phalanges of the hand", "Symphalangism of middle phalanx of finger", "Symptomatic seizures", "Syncope", "Syndactyly", "Synostosis involving bones of the hand", "Synostosis involving bones of the lower limbs", "Synostosis involving bones of the upper limbs", "Synostosis involving digits", "Synostosis of carpal bones", "Synostosis of carpals tarsals", "Synostosis of joints", "Synostosis of metacarpals metatarsals", "Synovitis", "Syringomyelia", "Systemic lupus erythematosus", "T cell lymphoma", "T lymphocytopenia", "Tachycardia", "Tachypnea", "Talipes calcaneovalgus", "Talipes equinovalgus", "Talipes equinovarus", "Talipes valgus", "Tall chin", "Tall stature", "Tapered distal phalanges of finger", "Tapered finger", "Tarsal synostosis", "Telangiectasia", "Telangiectasia of the skin", "Telecanthus", "Temperature instability", "Temporal cortical atrophy", "Temporal optic disc pallor", "Temporal pattern", "Tendon xanthomatosis", "Tented upper lip vermilion", "Teratoma", "Testicular adrenal rest tumor", "Testicular atrophy", "Testicular dysgenesis", "Tetany", "Tetralogy of fallot", "Tetraparesis", "Tetraplegia", "Tetraplegia tetraparesis", "Thenar muscle atrophy", "Thick cerebral cortex", "Thick corpus callosum", "Thick eyebrow", "Thick hair", "Thick lower lip vermilion", "Thick nasal alae", "Thick upper lip vermilion", "Thick vermilion border", "Thickened calvaria", "Thickened cortex of long bones", "Thickened ears", "Thickened helices", "Thickened nuchal skin fold", "Thickened ribs", "Thickened skin", "Thin bony cortex", "Thin clavicles", "Thin eyebrow", "Thin lower lip vermilion", "Thin nail", "Thin ribs", "Thin skin", "Thin upper lip vermilion", "Thin vermilion border", "Thinning of descemet membrane", "Third degree atrioventricular block", "Thoracic aortic aneurysm", "Thoracic dysplasia", "Thoracic hypoplasia", "Thoracic kyphoscoliosis", "Thoracic kyphosis", "Thoracic scoliosis", "Thoracolumbar kyphoscoliosis", "Thoracolumbar kyphosis", "Thoracolumbar scoliosis", "Thrombocytosis", "Thromboembolism", "Thrombophlebitis", "Thymus hyperplasia", "Thyroid adenoma", "Thyroid carcinoma", "Thyroiditis", "Tibial bowing", "Tibial torsion", "Tibialis muscle weakness", "Tics", "Tiger tail banding", "Tinnitus", "Tip toe gait", "Tissue ischemia", "Titubation", "Toe clinodactyly", "Toe syndactyly", "Toe walking", "Toenail dysplasia", "Tongue atrophy", "Tongue fasciculations", "Tongue nodules", "Tongue thrusting", "Tonic seizure", "Tooth malposition", "Torsade de pointes", "Torsion dystonia", "Total anomalous pulmonary venous return", "Toxemia of pregnancy", "Tracheal stenosis", "Tracheobronchomalacia", "Tracheoesophageal fistula", "Tracheomalacia", "Tractional retinal detachment", "Transient global amnesia", "Transient ischemic attack", "Transient neonatal diabetes mellitus", "Transient neutropenia", "Transposition of the great arteries", "Tremor", "Tremor by anatomical site", "Triangular face", "Triangular mouth", "Triangular shaped phalanges of the hand", "Triceps weakness", "Trichorrhexis nodosa", "Tricuspid atresia", "Tricuspid stenosis", "Tricuspid valve prolapse", "Trigonocephaly", "Triphalangeal thumb", "Trismus", "Tritanomaly", "Trophic changes related to pain", "True hermaphroditism", "Truncal ataxia", "Truncal obesity", "Truncal titubation", "Truncus arteriosus", "Tube feeding", "Tubulointerstitial nephritis", "Turricephaly", "Type 1 fibers relatively smaller than type 2 fibers", "Type 1 muscle fiber atrophy", "Type 2 muscle fiber atrophy", "Type 2 muscle fiber predominance", "Type i diabetes mellitus", "Type i transferrin isoform profile", "Type ii diabetes mellitus", "Type ii lissencephaly", "Type ii transferrin isoform profile", "Typical absence seizure", "U shaped upper lip vermilion", "Ulcerative colitis", "Ulnar bowing", "Ulnar claw", "Ulnar deviation of finger", "Ulnar deviation of the 2nd finger", "Ulnar deviation of the hand", "Ulnar deviation of the hand or of fingers of the hand", "Ulnar deviation of the wrist", "Uncombable hair", "Unconjugated hyperbilirubinemia", "Uncontrolled eye movements", "Underdeveloped nasal alae", "Underdeveloped supraorbital ridges", "Underdeveloped tragus", "Undetectable electroretinogram", "Undetectable light and dark adapted electroretinogram", "Undetectable visual evoked potentials", "Unexplained fevers", "Unilateral primary pulmonary dysgenesis", "Unilateral ptosis", "Unilateral renal agenesis", "Unsteady gait", "Unusual fungal infection", "Unusual infection", "Unusual infection by anatomical site", "Unusual skin infection", "Upgaze palsy", "Uplifted earlobe", "Upper airway obstruction", "Upper extremity joint dislocation", "Upper eyelid coloboma", "Upper limb amyotrophy", "Upper limb asymmetry", "Upper limb hypertonia", "Upper limb muscle weakness", "Upper limb pain", "Upper limb postural tremor", "Upper limb spasticity", "Upper limb undergrowth", "Upper motor neuron dysfunction", "Upslanted palpebral fissure", "Ureteral duplication", "Ureteral obstruction", "Ureteral stenosis", "Ureterocele", "Ureteropelvic junction obstruction", "Urethral atresia", "Urethral obstruction", "Urethral stenosis", "Urethral stricture", "Urethral valve", "Urethrovaginal fistula", "Uric acid nephrolithiasis", "Urinary bladder sphincter dysfunction", "Urinary glycosaminoglycan excretion", "Urinary incontinence", "Urinary retention", "Urinary tract neoplasm", "Urinary urgency", "Urogenital fistula", "Urogenital sinus anomaly", "Urticaria", "Uterine prolapse", "Uterus didelphys", "Uveal melanoma", "Uveitis", "Vacuolated lymphocytes", "Vaginal atresia", "Vaginal fistula", "Vaginal neoplasm", "Variable expressivity", "Varicose veins", "Vascular calcification", "Vascular dilatation", "Vascular neoplasm", "Vascular skin abnormality", "Vascular tortuosity", "Vasculitis", "Vegetative state", "Vein of galen aneurysmal malformation", "Velopharyngeal insufficiency", "Venous insufficiency", "Venous malformation", "Venous thrombosis", "Ventilator dependence with inability to wean", "Ventricular arrhythmia", "Ventricular escape rhythm", "Ventricular fibrillation", "Ventricular hypertrophy", "Ventricular preexcitation", "Ventricular septal hypertrophy", "Ventricular tachycardia", "Ventriculomegaly", "Verrucae", "Vertebral arch anomaly", "Vertebral clefting", "Vertebral compression fracture", "Vertebral fusion", "Vertebral hypoplasia", "Vertebral segmentation defect", "Vertebral wedging", "Vertical nystagmus", "Vertical supranuclear gaze palsy", "Vertigo", "Very long chain fatty acid accumulation", "Vestibular dysfunction", "Viral encephalitis", "Viral hepatitis", "Viral infection induced rhabdomyolysis", "Visceral angiomatosis", "Visual acuity test abnormality", "Visual agnosia", "Visual field defect", "Visual fixation instability", "Visual hallucinations", "Visual impairment", "Visual loss", "Vitamin b12 deficiency", "Vitiligo", "Vitreoretinopathy", "Vitreous floaters", "Vitreous hemorrhage", "Vitritis", "Vocal cord paralysis", "Vocal cord paresis", "Volvulus", "Vomiting", "Waddling gait", "Weak cry", "Weak voice", "Weakness due to upper motor neuron dysfunction", "Weakness of facial musculature", "Weakness of muscles of respiration", "Weakness of the intrinsic hand muscles", "Webbed neck", "Weight loss", "Wheezing", "White forelock", "White hair", "Wide anterior fontanel", "Wide cranial sutures", "Wide intermamillary distance", "Wide mouth", "Wide nasal bridge", "Wide nasal ridge", "Wide nose", "Wide pubic symphysis", "Widely patent fontanelles and sutures", "Widely spaced incisors", "Widely spaced teeth", "Widened cerebral subarachnoid space", "Widened subarachnoid space", "Widow s peak", "Woolly hair", "Wormian bones", "Wrist flexion contracture", "Writer s cramp", "X linked dominant inheritance", "X linked recessive inheritance", "Xanthelasma", "Xanthomatosis", "Xerostomia", "Y shaped metacarpals", "Yellow white lesions of the retina", "Young adult onset", "Zollinger ellison syndrome", "Zonular cataract"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "AASS", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD3", "ABCD4", "ABHD11", "ABHD12", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACO2", "ACOX1", "ACP2", "ACSF3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADK", "ADNP", "ADSL", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKT1", "AKT2", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALG1", "ALG12", "AMPD2", "ANAPC1", "ANAPC2", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANXA11", "AP1B1", "AP1S1", "AP1S2", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP4M1", "APOL2", "APP", "APRT", "ARCN1", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARID1A", "ARID2", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP6", "ARV1", "ARVCF", "ASAH1", "ASCC1", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG5", "ATG7", "ATIC", "ATL3", "ATP1A1", "ATP2A2", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATPAF2", "ATRX", "ATXN10", "AURKA", "B3GALT6", "B3GAT3", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BBS4", "BCAP31", "BCAT2", "BCKDK", "BCR", "BCS1L", "BICD2", "BLM", "BLVRA", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD4", "BRIP1", "BUB1B", "BUB3", "BUD23", "C12orf57", "C19orf70", "C1QBP", "CAD", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CAPN1", "CAPN5", "CARS", "CASK", "CAST", "CC2D1A", "CCDC22", "CCDC47", "CCT5", "CD109", "CD2AP", "CD320", "CDC42", "CDC45", "CDC73", "CDH2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKN2A", "CELF2", "CENPE", "CEP250", "CEP290", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHORDC1", "CHST14", "CHUK", "CISD2", "CIZ1", "CLASP1", "CLCC1", "CLCN6", "CLCN7", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CNNM4", "CNOT1", "CNOT3", "CNP", "COA3", "COA7", "COASY", "COG5", "COG6", "COG7", "COG8", "COLEC12", "COLGALT1", "COMT", "COPA", "COPB1", "COPB2", "COQ8A", "COX1", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "CPNE1", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRKL", "CRTAP", "CSNK2A1", "CSNK2B", "CSTB", "CTBP1", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTSA", "CTSC", "CTU2", "CUL3", "CUL4B", "CWC27", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "DARS", "DARS2", "DAXX", "DBT", "DCAF8", "DCPS", "DCTN1", "DCTN4", "DCXR", "DDB1", "DDOST", "DDRGK1", "DDX3X", "DDX41", "DDX6", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIP2B", "DKC1", "DLAT", "DLD", "DLG3", "DLST", "DNAAF5", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC21", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DPP9", "DPYSL5", "DSC3", "DSE", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S3", "EIF3F", "EIF4A3", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELMO2", "ELP1", "ELP2", "ELP4", "EMC1", "EMD", "EMG1", "EPB41", "EPHX2", "EPRS", "EPS15L1", "ERAL1", "ERAP1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ESS2", "ETFA", "ETFB", "ETFDH", "EWSR1", "EXOC2", "EXOC7", "EXOC8", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "FAH", "FAM50A", "FANCG", "FANCI", "FAR1", "FARSA", "FARSB", "FASN", "FASTKD2", "FDFT1", "FDPS", "FDXR", "FECH", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FOXRED1", "FRG1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "G6PD", "GAA", "GAL", "GALK1", "GALM", "GALNS", "GALNT2", "GAMT", "GANAB", "GAPVD1", "GARS", "GATAD2B", "GATB", "GBA", "GCDH", "GCLC", "GDAP2", "GDI1", "GEMIN4", "GEMIN5", "GFM1", "GFPT1", "GGCX", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLRX5", "GLS", "GLT8D1", "GM2A", "GMPPA", "GMPPB", "GNA11", "GNAI2", "GNAI3", "GNAO1", "GNPAT", "GNS", "GOSR2", "GOT2", "GPAA1", "GPD2", "GPHN", "GPI", "GPKOW", "GPRASP2", "GPT2", "GRHPR", "GSR", "GSS", "GSTM3", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H2AFY", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBCH", "HIST1H1E", "HK1", "HLA-A", "HLA-B", "HLA-C", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HPRT1", "HPS6", "HS2ST1", "HSD17B10", "HSD17B4", "HSPA9", "HSPD1", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT52", "IGBP1", "IGF2BP2", "IGF2R", "IGHMBP2", "IKBKB", "IMPAD1", "IMPDH1", "INF2", "INTS1", "IQCB1", "IRF2BPL", "IRS4", "ITCH", "ITGA2", "ITPA", "IVD", "JAGN1", "JAM3", "JUP", "KARS", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIAA0319L", "KIDINS220", "KIF11", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF4A", "KIFBP", "KLC2", "KNSTRN", "L2HGDH", "LAMB1", "LAMC1", "LAMP2", "LAMTOR2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDLR", "LEMD2", "LEMD3", "LETM1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2L", "LMBRD1", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRPAP1", "LRPPRC", "LRRC8A", "LRSAM1", "LSS", "LZTFL1", "MACF1", "MAD1L1", "MAGED2", "MAGT1", "MAN2B1", "MAP1B", "MAP2K1", "MAP3K7", "MAPK1", "MAPRE2", "MARS", "MARS2", "MAT2A", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCFD2", "MCM2", "MCM4", "MCM5", "MCM6", "MCM7", "MDH1", "MDH2", "MECP2", "MECR", "MED17", "MED23", "MED25", "MESD", "MFF", "MFN2", "MFSD8", "MIA3", "MICU1", "MID1", "MIF", "MIPEP", "MMAB", "MOCOS", "MOCS1", "MOGS", "MPDU1", "MPG", "MPI", "MPP5", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS28", "MRPS34", "MRPS35", "MRPS7", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MSTO1", "MTAP", "MTCH1", "MTHFD1", "MTOR", "MTPAP", "MTR", "MTX2", "MUT", "MVD", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NADK2", "NADSYN1", "NAGLU", "NANS", "NARS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCDN", "NCSTN", "ND1", "ND5", "NDE1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA6", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEFL", "NEK9", "NELFA", "NEMF", "NFKBIL1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NNT", "NONO", "NOP10", "NOP56", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPM1", "NSD1", "NSD2", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NXN", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSBPL2", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPN1", "PAFAH1B1", "PALLD", "PANX1", "PARK7", "PARN", "PAX6", "PBRM1", "PC", "PCBD1", "PCCA", "PCCB", "PCK2", "PCNA", "PDCD6", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDK3", "PDP1", "PDSS1", "PDSS2", "PDXK", "PEPD", "PET100", "PEX14", "PEX19", "PEX5", "PEX6", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PISD", "PITRM1", "PKN1", "PLAA", "PLD3", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLD1", "POLE", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR3A", "POMGNT2", "PON2", "POP1", "POR", "PPA2", "PPIB", "PPIL1", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R5D", "PPP3CA", "PPT1", "PQBP1", "PRCC", "PREPL", "PRKACA", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSMB4", "PSMC3", "PSMD12", "PSMG2", "PTCD3", "PTDSS1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUF60", "PURA", "PUS1", "PUS7", "PXMP2", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QRSL1", "RAB11B", "RAB18", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB7A", "RABL3", "RAC1", "RAD21", "RAD50", "RALA", "RANBP2", "RAPGEF2", "RARS", "RARS2", "RBM10", "RBM12", "RBM28", "RBM8A", "RBMX", "RDH11", "RDX", "REEP2", "REPS1", "RFC1", "RFC2", "RFT1", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF2", "RNF213", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL26", "RPL27", "RPL31", "RPL35", "RPL35A", "RPL5", "RPS10", "RPS14", "RPS15A", "RPS17", "RPS19", "RPS20", "RPS23", "RPS24", "RPS28", "RPS29", "RPS6KA3", "RPS7", "RPSA", "RREB1", "RRM2B", "RRP7A", "RTN2", "RTN4IP1", "SALL2", "SAMHD1", "SAR1B", "SARS", "SARS2", "SBDS", "SC5D", "SCAF1", "SCARB2", "SCO1", "SCO2", "SCP2", "SCYL1", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SF3B1", "SF3B4", "SFXN4", "SGPL1", "SH3GL1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SLC12A2", "SLC16A1", "SLC19A1", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC27A4", "SLC2A1", "SLC33A1", "SLC39A14", "SLC9A3R1", "SLTM", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMG8", "SMN1*", "SMPD4", "SMS", "SNAP29", "SNRNP200", "SNRPE", "SOAT1", "SON", "SORD", "SPART", "SPAST", "SPATA5", "SPEN", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQOR", "SRCAP", "SRP54", "SRP72", "SRSF2", "SSBP1", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD7", "STAT1", "STAT3", "STK4", "STT3A", "STT3B", "STUB1", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SYNE2", "TAF15", "TALDO1", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCOF1", "TCTN3", "TECR", "TELO2", "TERF2IP", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIMM22", "TIMM50", "TIMMDC1", "TJP2", "TKFC", "TKT", "TMCO1", "TMEM126A", "TMEM126B", "TMEM165", "TMEM199", "TMEM38B", "TMEM43", "TMEM70", "TMPO", "TMPO", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOMM40", "TOP2A", "TOR1A", "TOR1AIP1", "TP53", "TPI1", "TPM1", "TPM3", "TPP1", "TPP2", "TPRKB", "TRAPPC11", "TRAPPC4", "TRIM28", "TRIM32", "TRIP12", "TRIP13", "TRIP4", "TRIT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSPYL1", "TTC19", "TTC37", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWNK", "TXNDC15", "UBA1", "UBA5", "UBAC2", "UBE4A", "UBE4B", "UBIAD1", "UBR7", "UBTF", "UFC1", "UFD1", "UFSP2", "UGDH", "UGP2", "UMPS", "UNC119", "UNC45A", "UNG", "UPF3B", "UQCC2", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP7", "USP8", "USP9X", "VAMP7", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VIPAS39", "VMA21", "VPS13A", "VPS13D", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP11", "WDR1", "WDR34", "WDR36", "WDR4", "WDR45B", "WDR73", "WFS1", "WNK1", "WRN", "XPNPEP3", "XRCC1", "YARS", "YARS2", "YIF1B", "YIPF5", "YME1L1", "YWHAE", "YWHAG", "YY1", "ZC3H14", "ZCCHC8", "ZFR", "ZMPSTE24", "ZNF644", "ZNF687", "ZPR1"], "leading_proteins": ["AAAS", "AARS2", "ABAT", "ABCB6", "ABCB7", "ABCD4", "ABHD12", "ACADVL", "ACAT2", "ACOX1", "ACP2", "ACTN1", "ACTN4", "ADA", "ADAM17", "ADAR", "ADD3", "ADK", "ADNP", "AFG3L2", "AGPS", "AHCY", "AIFM1", "AIP", "AK2", "AKT1", "AKT2", "ALDH18A1", "AMPD2", "ANAPC1", "ANAPC2", "ANKLE2", "AP1B1", "AP2M1", "AP2S1", "AP3B1", "APP", "ARHGEF1", "ARID1A", "ARID2", "ARVCF", "ASNA1", "ATL3", "ATP2A2", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A2", "ATP6V1B2", "B3GALT6", "B4GALT1", "B4GAT1", "BAZ1B", "BBS4", "BCR", "BICD2", "BLM", "BMS1", "BRAT1", "BUB1B", "CALD1", "CAMK2G", "CANT1", "CAPN5", "CASK", "CCDC22", "CCDC47", "CCT5", "CD109", "CD320", "CDC42", "CDC45", "CDC73", "CDH2", "CDK4", "CEP290", "CERS1", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHMP1A", "CHORDC1", "CHST14", "CHUK", "CLCN7", "CLN5", "CLN6", "CLPP", "CLTC", "CNNM4", "CNOT1", "CNOT3", "COA3", "COG6", "COLEC12", "COPB2", "COX15", "COX2", "COX5A", "CPT2", "CRTAP", "CSNK2B", "CTH", "CTNNA1", "CTNNB1", "CTPS1", "CTSA", "CTU2", "CUL4B", "CYFIP2", "DCAF8", "DCTN1", "DDRGK1", "DGCR8", "DHCR24", "DHCR7", "DHX16", "DHX37", "DIABLO", "DKC1", "DNAAF5", "DNAJC13", "DOCK7", "DSC3", "DST", "DYM", "DYNC2H1", "ECE1", "EED", "EEF1A2", "EFTUD2", "EIF2B2", "EIF2S3", "EIF4H", "ELMO2", "ELP1", "EMD", "ERAP1", "EWSR1", "EXOC2", "EXOC7", "EXOSC2", "EXOSC3", "EZH2", "EZR", "FAH", "FANCG", "FAR1", "FECH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FMR1", "FOXRED1", "FRG1", "FUCA1", "FUS", "FXR1", "GAA", "GAL", "GALNS", "GALNT2", "GBA", "GEMIN5", "GGCX", "GIGYF2", "GLA", "GLB1", "GLDC", "GLT8D1", "GMPPB", "GNPAT", "GNS", "GSR", "GUSB", "GYS1", "H2AFY", "HCCS", "HELLS", "HERC2", "HK1", "HLA-A", "HLA-B", "HLA-C", "HMMR", "HMOX1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPU", "HPS6", "HYOU1", "IDH2", "IFT52", "IGF2BP2", "IGF2R", "IMPAD1", "INTS1", "IQCB1", "IRS4", "ITGA2", "JAM3", "KARS", "KIAA0319L", "KIF11", "KIF20A", "KIF22", "KIF23", "KIF4A", "KIFBP", "KNSTRN", "LAMB1", "LAS1L", "LBR", "LEMD3", "LLGL1", "LMAN1", "LMBRD1", "LMNA", "LMNB1", "LMNB2", "LRBA", "LRPAP1", "LZTFL1", "MAD1L1", "MAGT1", "MAN2B1", "MAP2K1", "MAPRE2", "MATR3", "MBOAT7", "MCM6", "MECP2", "MED17", "MED25", "MESD", "MFF", "MFN2", "MFSD8", "MICU1", "MID1", "MIF", "MPG", "MPP5", "MPV17", "MRPS16", "MRPS35", "MSH2", "MSH3", "MSN", "MTAP", "MTCH1", "MTOR", "MTR", "MTX2", "MYH14", "MYH9", "NAA10", "NADK2", "NAGLU", "NBAS", "NBN", "NCAPD2", "NCAPG2", "NCDN", "NCSTN", "ND1", "NDE1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFS2", "NDUFS6", "NDUFS7", "NEFL", "NFKBIL1", "NNT", "NONO", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPM1", "NSD1", "NSD2", "NSDHL", "NUMA1", "NUP107", "NUP188", "NUP37", "NUP93", "NXN", "OBSL1", "OCLN", "OCRL", "OPA1", "OPA3", "P4HA2", "PANX1", "PDHB", "PDP1", "PDXK", "PHF6", "PHIP", "PI4KA", "PIBF1", "PIGG", "PIGS", "PIGT", "PIK3C2A", "PLD3", "PLEC", "PLOD3", "PMPCA", "PMS1", "PNKP", "PNPO", "POFUT1", "POLA1", 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0.1302152537326229 7.142313942893836 4.247239237941681 3.086075071395461 0.2389623217115766 1.0 0.0011728813459652 2.936982989091669e-08 1.8189921011446102e-11 9.426242151866604e-14 +Porphyrin and chlorophyll metabolism 3 14 2.4435864292965466 0.0145420859372011 3.728155339805826 13.315533980582524 1.2215621624941897 0.2689555702886888 1.770547470360957 1.4201912411596824 1.0389071586082248 0.2908939383930566 0.0213770889355645 0.0039064712270754 0.015225007352257 0.0828772873031817 0.002252196025852 +Tight junction 13 40 2.244057805941626 0.0248286822970242 12.03883495145631 37.570388349514566 -0.1404427951014139 0.6900835645690857 6.39466150238154 4.18647809958572 0.6778277794028751 0.2861793267138341 1.0 1.0 1.0 0.3703488858590576 0.0041393793420635 +Viral myocarditis 5 12 2.0362731703285117 0.0417229323800434 4.031553398058253 11.228155339805824 0.0319814940949768 0.5543700591424958 2.250452924114055 1.5125313108034515 0.956572263574295 0.3192370987906132 1.0 1.0 1.0 0.2332121755087385 0.1114244714574529 +Abc transporters 1 10 2.029672406444673 0.042389849524596 2.3762135922330097 6.366504854368932 0.6645221155900782 0.3307647417699358 1.8079428939478197 2.1798157082242287 1.1702884010083077 0.2791394174824396 1.0 0.0901405579438761 0.1741653971767485 0.0828772873031817 0.2539261987860491 +Cell adhesion molecules cams 7 14 1.9948115962624056 0.046063432131902 4.043689320388349 9.91019417475728 0.3640395302172229 0.4325707543794381 2.3114392567097153 2.512916721209252 1.1817978240178808 0.3174557953274378 1.0 1.0 1.0 0.1411134338084059 0.1208874805839759 +Glycerophospholipid metabolism 2 18 1.985344318725688 0.0471061763900022 5.553398058252427 16.104368932038835 0.8448777148315795 0.3373638196000335 3.045697762577092 2.514285464673758 1.2272389207362138 0.3056726473181033 0.0567667721825774 0.0265864003984115 0.0145863017156454 0.1411134338084059 0.2675058784158126 diff --git a/msigdb_kegg/metrics.json b/msigdb_kegg/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..3de0aacc27b55108166317ea9902fa08edc11b80 --- /dev/null +++ b/msigdb_kegg/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 181, + "title": "Average number of proteins per term", + "value": 17.96132596685083 +} \ No newline at end of file diff --git a/msigdb_kegg/paths.json b/msigdb_kegg/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..d52b658dcda7e1aea4203390fe43d0cbc9eb8218 --- /dev/null +++ b/msigdb_kegg/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_kegg/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/msigdb_kegg/result.tsv b/msigdb_kegg/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..10cea2ac48d7a598f39482868b270d932badea4f --- /dev/null +++ b/msigdb_kegg/result.tsv @@ -0,0 +1,60 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Lysosome 0.6676972948231756 3.9030371457612434 9.499311704441736e-05 0.0170475878892379 0.0057312513950132 56 Q14108,O15118,P10253,O14773,P54802,O75503,Q8NCC3,P06280,P16278,P11717,P20645,Q9Y487,P15586,Q8NHS3,P10619,O00754,P07602,P50897,Q9UMR5,Q93050,P08236,P04066,Q15012,P61916,Q99523,P11117,O43681 27 +Porphyrin and chlorophyll metabolism 0.7440007481942749 2.4435864292965466 0.0145420859372011 0.9294506900585072 0.4458987067725546 14 P22830,Q7KZN9,P30519 3 +Tight junction 0.5241388838477137 2.244057805941626 0.0248286822970242 0.98944042708155 0.5015422309759063 40 P35579,P12814,P35580,P35221,Q7Z406,O43707,Q92797,P31751,Q8N3R9,Q9BX67,Q13813,Q16625,O14936 13 +Renin angiotensin system 0.9606738604780972 2.1994536053447415 0.0278456845901051 0.993973395215316 0.5015422309759063 4 Q9UIQ6,P10619 2 +Glycosaminoglycan biosynthesis keratan sulfate 0.9442307692307694 2.0479833103329694 0.0405616347580397 0.9994439784740844 0.5015422309759063 3 P15291,O60512 2 +Glycosphingolipid biosynthesis lacto and neolacto series 0.9442307692307694 2.0479833103329694 0.0405616347580397 0.9994439784740844 0.5015422309759063 3 P15291,O60512 2 +Viral myocarditis 0.6929110282779646 2.0362731703285113 0.0417229323800434 0.9995534313430928 0.5015422309759063 12 P35579,P35580,P10321,Q7Z406,P30511 5 +Abc transporters 0.7114341493304953 2.029672406444673 0.042389849524596 0.9996063030093484 0.5015422309759063 10 O75027 1 +Cell adhesion molecules cams 0.6576933058306192 1.9948115962624056 0.046063432131902 0.9998036508647792 0.5015422309759063 14 P10321,Q9BY67,Q92896,P30511,P10586,Q9BX67,Q16625 7 +Glycerophospholipid metabolism 0.5845646398251612 1.9853443187256876 0.0471061763900022 0.999838914418646 0.5015422309759063 18 Q8NCC3,Q9HCL2 2 +Hypertrophic cardiomyopathy hcm 0.670933011186546 1.8771739502260367 0.0604942565983366 0.9999875606259292 0.5041377017898019 11 P54619,P16615,P02545,P09493,P67936 5 +Calcium signaling pathway 0.5576993723332518 1.8307158456727 0.0671429667194989 0.9999965602147116 0.5041377017898019 19 Q13555,P21796,P16615,P45880 4 +Riboflavin metabolism 0.8257882014371387 1.82316459468647 0.0682784656724928 0.9999972407559898 0.5041377017898019 5 P11117,Q9NPH0 2 +Notch signaling pathway 0.6932947884010959 1.814295270903971 0.069632279252735 0.9999978792534648 0.5041377017898019 9 P78536,Q13573 2 +Adherens junction 0.5297680043673588 1.7107670166826645 0.0871241306412926 0.9999999316839684 0.5159515187421125 23 P12814,P35221,Q9NWH9,O43707,P10586,Q9Y6W5,Q9UQB8,P35222 8 +Sphingolipid metabolism 0.6172551010672577 1.6970117535969804 0.0896944384301086 0.9999999589906872 0.5159515187421125 13 P16278,Q16739,O43681,O95470,Q9NRA0,P04062,P06280 7 +Epithelial cell signaling in helicobacter pylori infection 0.5208890929370266 1.6693047588989187 0.0950569975858959 0.9999999859252096 0.5159515187421125 24 P78536,Q9Y487,Q93050,Q9NWH9 4 +Hematopoietic cell lineage 0.7338643229881869 1.5739656580109704 0.1154953890667873 0.9999999997747222 0.5159515187421125 2 P02786 1 +Ecm receptor interaction 0.6573848859647381 1.5333771705553148 0.1251829503692301 0.9999999999693084 0.5159515187421125 8 Q7L0J3 1 +Leukocyte transendothelial migration 0.4996522666284858 1.5247701422669218 0.1273164395798729 0.999999999980272 0.5159515187421125 24 P12814,P26038,Q13464,O43707,O75116,Q9BX67,Q16625 7 +Cysteine and methionine metabolism 0.5317622106860652 1.4606117382785264 0.1441220230853681 0.9999999999994158 0.5159515187421125 16 Q13126,O43865 2 +Proteasome 0.4380163516289561 1.450119405052421 0.1470252246735321 0.999999999999684 0.5159515187421125 36 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Allograft rejection 0.7301079974634257 1.4357280984856835 0.151079726482497 0.9999999999998668 0.5159515187421125 5 P30511,P10321 2 +Autoimmune thyroid disease 0.7301079974634257 1.4357280984856835 0.151079726482497 0.9999999999998668 0.5159515187421125 5 P30511,P10321 2 +Graft versus host disease 0.7301079974634257 1.4357280984856835 0.151079726482497 0.9999999999998668 0.5159515187421125 5 P30511,P10321 2 +Dilated cardiomyopathy 0.5776685188785001 1.3682249712005232 0.1712416675255803 0.9999999999999984 0.526805861566675 10 P02545,P16615,P67936,P09493 4 +Regulation of actin cytoskeleton 0.3905541953745389 1.3676987178970967 0.171406401437248 0.9999999999999984 0.526805861566675 54 P35579,P12814,P35580,Q86VI3,Q7Z406,Q13464,Q92888,O75116,O43707,Q96F07,Q7L576,Q9UQB8,Q14185 13 +Other glycan degradation 0.594857148231327 1.1573163909697184 0.2471431192293223 1.0 0.6042303076365733 7 P16278,Q9BTY2,P04066 3 +Mismatch repair 0.4510785785310091 1.1395982986848257 0.2544536944726285 1.0 0.6060015618361285 19 Q9UQ84,P41440,P40938 3 +Steroid biosynthesis 0.4989041579736856 1.057256618719256 0.2903944860690268 1.0 0.6408016049128642 13 Q16850,Q15392 2 +Glycosaminoglycan degradation 0.558034034139804 0.993142565228232 0.3206404832247058 1.0 0.6725298347950741 7 P16278,P15586,P54802 3 +Glycerolipid metabolism 0.4592857854486852 0.8430269157087985 0.3992133907102015 1.0 0.7373226910055765 13 Q9HCL2,P30837 2 +Type i diabetes mellitus 0.5407054384917435 0.783263124727135 0.4334726127899073 1.0 0.7544090664901272 6 P30511,P10321 2 +Galactose metabolism 0.4354808616414108 0.764622685061674 0.4444962568688297 1.0 0.7662268808881733 14 P16278,P15291,P06280 3 +Nicotinate and nicotinamide metabolism 0.4907795990461901 0.7007381667076812 0.4834664326524271 1.0 0.7883551739647686 7 P43490 1 +Amyotrophic lateral sclerosis als 0.432219279948231 0.6563777992405458 0.5115810711889619 1.0 0.8025526130356009 11 P07197,P07196 2 +Glycosylphosphatidylinositol gpi anchor biosynthesis 0.5053094692166757 0.6415284520358977 0.5211794014707833 1.0 0.8062689886001007 6 Q969N2 1 +Selenoamino acid metabolism 0.4176919843565907 0.6244798692962028 0.5323124867661668 1.0 0.8165132212260695 13 O43865 1 +Focal adhesion 0.3280627004287318 0.5862507011894427 0.5577070547414482 1.0 0.8273310140087867 41 P07942,P12814,Q13464,Q9NWH9,O43707,O75116,Q14185 7 +Vibrio cholerae infection 0.3611823541436229 0.5634747269768527 0.5731116648698706 1.0 0.8273310140087867 21 Q9Y487 1 +O glycan biosynthesis 0.5098109287411687 0.5580676457810289 0.5767981928104919 1.0 0.8273310140087867 5 Q10472,O43505 2 +Cytosolic dna sensing pathway 0.4243531147344 0.537690214058804 0.5907909363776853 1.0 0.8273310140087867 9 Q9BUI4,Q7Z434,Q9NZI8,P55265 4 +Lysine degradation 0.3532543114728807 0.5255754795200742 0.599183197286663 1.0 0.8273310140087867 24 P30837,Q9BWD1 2 +Snare interactions in vesicular transport 0.3722008347461826 0.5153010138001913 0.6063426906336224 1.0 0.8273310140087867 16 O15400,O43752,O60499,P51809 4 +Systemic lupus erythematosus 0.3953884791189739 0.512412335672525 0.6083624594400632 1.0 0.8273310140087867 13 P12814,P19474 2 +Arrhythmogenic right ventricular cardiomyopathy arvc 0.3871636116825017 0.5082227182603042 0.6112971603319604 1.0 0.8273310140087867 14 P12814,P35221,P50402,P17301,Q14126,P16615,O43707,P02545,P19022,P35222 10 +Basal cell carcinoma 0.4898295766904696 0.4875486637338792 0.6258695654808801 1.0 0.8273310140087867 5 Q9UJX6,O14641,P35222,P04637 4 +Antigen processing and presentation 0.3377047727171844 0.4196838970601247 0.6747163902315398 1.0 0.8419618590299791 19 Q99538,Q9UL46,P30511,P10321 4 +Ether lipid metabolism 0.4677763026266077 0.4136211863628372 0.6791515547976628 1.0 0.8419618590299791 5 O00116 1 +Oxidative phosphorylation 0.2872698631291361 0.3991176986749808 0.6898064818468019 1.0 0.8463106923453148 69 P03886,Q9Y487,O43676,P00846,O75251,P25705,Q93050,O75964,O75380,Q7KZN9 10 +N glycan biosynthesis 0.3325855349915522 0.3897969456001902 0.6966867025384083 1.0 0.8463106923453148 20 O60476,O60512,P15291 3 +Apoptosis 0.3297013487334639 0.375470739338129 0.7073104039246603 1.0 0.8478356497375067 18 P17655,P31751,O95831 3 +Small cell lung cancer 0.3388549658610438 0.3065393748770955 0.7591940049596877 1.0 0.8717053477354988 15 P11802,P07942,P17301,P06756,P31751,O15111,P31749 7 +Colorectal cancer 0.3366586235499015 0.2478524243511451 0.8042485913366699 1.0 0.8985740434070201 13 P20585,P31749,P31751 3 +Parkinsons disease 0.2698611705689588 0.2069454699060122 0.8360524452211349 1.0 0.9150844464748144 64 P03886,P21796,O43676,P00846,P45880,O75251,P25705,O75380 8 +Adipocytokine signaling pathway 0.2818789851819342 0.136222912253668 0.8916450626424 1.0 0.9354826952877956 18 P11166,P31751,Q9UKU0,P54619 4 +Endometrial cancer 0.304253479808966 0.128770207730355 0.8975394800110776 1.0 0.9354826952877956 12 P31749,P31751,P35221 3 +Jak stat signaling pathway 0.3113688548689339 0.1201453970583215 0.9043679711687148 1.0 0.9354826952877956 8 P31751,P31749 2 +Thyroid cancer 0.2952291014960685 0.093953783206843 0.9251458699254996 1.0 0.9354826952877956 9 P12270,Q92734,P35222,P06753 4 diff --git a/msigdb_kegg/selections.json b/msigdb_kegg/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..2465efde9d9edc4bf6fc9f868f85c07e36bb5929 --- /dev/null +++ b/msigdb_kegg/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Abc transporters", "Acute myeloid leukemia", "Adherens junction", "Adipocytokine signaling pathway", "Alanine aspartate and glutamate metabolism", "Aldosterone regulated sodium reabsorption", "Allograft rejection", "Alpha linolenic acid metabolism", "Alzheimers disease", "Amino sugar and nucleotide sugar metabolism", "Aminoacyl trna biosynthesis", "Amyotrophic lateral sclerosis als", "Antigen processing and presentation", "Apoptosis", "Arachidonic acid metabolism", "Arginine and proline metabolism", "Arrhythmogenic right ventricular cardiomyopathy arvc", "Ascorbate and aldarate metabolism", "Autoimmune thyroid disease", "Axon guidance", "B cell receptor signaling pathway", "Basal cell carcinoma", "Basal transcription factors", "Base excision repair", "Beta alanine metabolism", "Biosynthesis of unsaturated fatty acids", "Bladder cancer", "Butanoate metabolism", "Calcium signaling pathway", "Cardiac muscle contraction", "Cell adhesion molecules cams", "Cell cycle", "Chemokine signaling pathway", "Chronic myeloid leukemia", "Citrate cycle tca cycle", "Colorectal cancer", "Cysteine and methionine metabolism", "Cytokine cytokine receptor interaction", "Cytosolic dna sensing pathway", "Dilated cardiomyopathy", "Dna replication", "Dorso ventral axis formation", "Drug metabolism cytochrome p450", "Drug metabolism other enzymes", "Ecm receptor interaction", "Endocytosis", "Endometrial cancer", "Epithelial cell signaling in helicobacter pylori infection", "Erbb signaling pathway", "Ether lipid metabolism", "Fatty acid metabolism", "Fc epsilon ri signaling pathway", "Fc gamma r mediated phagocytosis", "Focal adhesion", "Folate biosynthesis", "Fructose and mannose metabolism", "Galactose metabolism", "Gap junction", "Glioma", "Glutathione metabolism", "Glycerolipid metabolism", "Glycerophospholipid metabolism", "Glycine serine and threonine metabolism", "Glycolysis gluconeogenesis", "Glycosaminoglycan biosynthesis chondroitin sulfate", "Glycosaminoglycan biosynthesis heparan sulfate", "Glycosaminoglycan biosynthesis keratan sulfate", "Glycosaminoglycan degradation", "Glycosphingolipid biosynthesis ganglio series", "Glycosphingolipid biosynthesis globo series", "Glycosphingolipid biosynthesis lacto and neolacto series", "Glycosylphosphatidylinositol gpi anchor biosynthesis", "Glyoxylate and dicarboxylate metabolism", "Gnrh signaling pathway", "Graft versus host disease", "Hedgehog signaling pathway", "Hematopoietic cell lineage", "Histidine metabolism", "Homologous recombination", "Huntingtons disease", "Hypertrophic cardiomyopathy hcm", "Inositol phosphate metabolism", "Insulin signaling pathway", "Jak stat signaling pathway", "Leishmania infection", "Leukocyte transendothelial migration", "Limonene and pinene degradation", "Long term depression", "Long term potentiation", "Lysine degradation", "Lysosome", "Mapk signaling pathway", "Maturity onset diabetes of the young", "Melanogenesis", "Melanoma", "Metabolism of xenobiotics by cytochrome p450", "Mismatch repair", "Mtor signaling pathway", "N glycan biosynthesis", "Natural killer cell mediated cytotoxicity", "Neuroactive ligand receptor interaction", "Neurotrophin signaling pathway", "Nicotinate and nicotinamide metabolism", "Nitrogen metabolism", "Nod like receptor signaling pathway", "Non homologous end joining", "Non small cell lung cancer", "Notch signaling pathway", "Nucleotide excision repair", "O glycan biosynthesis", "Olfactory transduction", "One carbon pool by folate", "Oocyte meiosis", "Other glycan degradation", "Oxidative phosphorylation", "P53 signaling pathway", "Pancreatic cancer", "Pantothenate and coa biosynthesis", "Parkinsons disease", "Pathogenic escherichia coli infection", "Pathways in cancer", "Pentose and glucuronate interconversions", "Pentose phosphate pathway", "Peroxisome", "Phenylalanine metabolism", "Phosphatidylinositol signaling system", "Porphyrin and chlorophyll metabolism", "Ppar signaling pathway", "Primary bile acid biosynthesis", "Primary immunodeficiency", "Prion diseases", "Progesterone mediated oocyte maturation", "Propanoate metabolism", "Prostate cancer", "Proteasome", "Protein export", "Proximal tubule bicarbonate reclamation", "Purine metabolism", "Pyrimidine metabolism", "Pyruvate metabolism", "Regulation of actin cytoskeleton", "Regulation of autophagy", "Renal cell carcinoma", "Renin angiotensin system", "Retinol metabolism", "Riboflavin metabolism", "Ribosome", "Rig i like receptor signaling pathway", "Rna degradation", "Rna polymerase", "Selenoamino acid metabolism", "Small cell lung cancer", "Snare interactions in vesicular transport", "Sphingolipid metabolism", "Spliceosome", "Starch and sucrose metabolism", "Steroid biosynthesis", "Steroid hormone biosynthesis", "Sulfur metabolism", "Systemic lupus erythematosus", "T cell receptor signaling pathway", "Taste transduction", "Taurine and hypotaurine metabolism", "Terpenoid backbone biosynthesis", "Tgf beta signaling pathway", "Thyroid cancer", "Tight junction", "Toll like receptor signaling pathway", "Tryptophan metabolism", "Type i diabetes mellitus", "Type ii diabetes mellitus", "Tyrosine metabolism", "Ubiquitin mediated proteolysis", "Valine leucine and isoleucine biosynthesis", "Valine leucine and isoleucine degradation", "Vascular smooth muscle contraction", "Vasopressin regulated water reabsorption", "Vegf signaling pathway", "Vibrio cholerae infection", "Viral myocarditis", "Wnt signaling pathway"], "available_proteins": ["AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAM17", "ADAR", "ADH5", "ADI1", "ADK", "ADO", "ADSL", "ADSS", "AFDN", "AGK", "AGL", "AGPAT1", "AGPS", "AHCY", "AHCYL1", "AIFM1", "AK1", "AK2", "AK3", "AK4", "AKR1A1", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALYREF", "AMPD2", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEX1", "APP", "APRT", "AQR", "ARF6", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ASAH1", "ASNA1", "ASNS", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKA", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BAIAP2", "BCAS2", "BCAT2", "BCR", "BECN1", "BIRC6", "BLM", "BLVRA", "BNIP1", "BPNT1", "BRCA1", "BUB1B", "BUB3", "BUD23", "BUD31", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN2", "CARS", "CASK", "CBR1", "CCDC12", "CCDC6", "CD47", "CDC20", "CDC23", "CDC27", "CDC42", "CDC45", "CDC5L", "CDC7", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDKN2A", "CDS2", "CETN2", "CFL1", "CFL2", "CHD8", "CHEK2", "CHERP", "CHKA", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHORDC1", "CHPF2", "CHST14", "CHUK", "CKB", "CKMT1A*", "CLN5", "CLTA", "CLTB", "CLTC", "CMAS", "CMPK1", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "COASY", "COMT", "COX1", "COX15", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPT1A", 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b/msigdb_reactome/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 1409, + "title": "Average number of proteins per term", + "value": 20.888573456352024 +} \ No newline at end of file diff --git a/msigdb_reactome/paths.json b/msigdb_reactome/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a321575de4a21e3fd07ad8e336e4b5438f407bba --- /dev/null +++ b/msigdb_reactome/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/msigdb_reactome/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/msigdb_reactome/result.tsv b/msigdb_reactome/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..707ec77d9d33f8d19998b6140719976accbae5da --- /dev/null +++ b/msigdb_reactome/result.tsv @@ -0,0 +1,500 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Transport of small molecules 0.4323012665594853 2.788968201314301 0.0052876256423384 0.9994300895674788 0.0856352244833889 171 O15118,Q8WTV0,P20618,P30519,Q01650,O75027,P28072,P60900,P11166,P21796,Q8N4V1,O00231,Q70HW3,Q9UBX3,Q9NWR8,Q9Y487,P28074,P28070,P53985,P16615,P02786,Q6PIU2,Q9HD20,Q9UBI6,P30825,Q9BPX6,P49721,P55011,P45880,P51790,Q93050,P51798,Q9Y6M7,P61916,Q13555,Q9UNS2,Q9H4I9,Q99436,Q8IYU8 39 +Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.7054526336307289 2.743230242451003 0.0060838011633934 0.9998155731195572 0.0941986355958395 20 Q02818,P07942,Q06481,Q8NBJ4,Q07065,O43493,Q9BTY2,P05067 8 +Gpcr ligand binding 0.8594122578774266 2.7124911455369056 0.0066779565455972 0.9999205830388664 0.1000983060930476 10 P05067,P42892,P22466 3 +Peptide ligand binding receptors 0.9103939791503914 2.6371915943172937 0.0083595601236099 0.9999927035918128 0.1152078367249948 8 P05067,P42892,P22466 3 +Class a 1 rhodopsin like receptors 0.9103939791503914 2.6371915943172937 0.0083595601236099 0.9999927035918128 0.1152078367249948 8 P05067,P42892,P22466 3 +N glycan antennae elongation 0.9689645701730294 2.5812851549829428 0.0098433238508726 0.9999991152443226 0.1320880314845667 2 O60512 1 +Phase i functionalization of compounds 0.7543707537081208 2.495990938453758 0.0125605810144089 0.9999999815821572 0.149981852960188 14 P30837,P07099 2 +Sema4d in semaphorin signaling 0.8703032120418729 2.470963015871251 0.0134749753795639 0.9999999950074586 0.1564865310122269 8 P35579,P35580,Q7Z406,Q13464,O75116 5 +Metabolism of porphyrins 0.8017744117264131 2.4530339444912244 0.0141656970518169 0.9999999981390644 0.1609634447258874 10 P22830,Q7KZN9,P30519 3 +Receptor type tyrosine protein phosphatases 0.9258445482010424 2.4033534788683393 0.0162454757701895 0.9999999999050664 0.1802352390566697 2 P10586 1 +Epha mediated growth cone collapse 0.8820757727708988 2.3988798877239352 0.0164453081093425 0.9999999999286971 0.181026868172372 7 P35579,P35580,Q7Z406,Q13464,O75116 5 +Rho gtpase cycle 0.404245519094672 2.3677562608438825 0.0178963215645293 0.999999999991094 0.1926237478717264 172 P78371,P84095,Q86VI3,P30519,Q96N67,P06753,Q13505,Q9Y5S2,Q9UQB8,Q92888,Q96JJ3,Q86UP2,P02786,Q07960,Q07065,Q14739,O75116,Q9BXS4,P67936,Q13813,P20700,P12814,Q9NZM3,O15173,Q96RU3,Q13464,O75976,P61201,Q96F07,Q7L576,P41440,P11274,Q14185,Q8NBN3,Q9Y6M7,P08670,Q01082,Q9BT78,O75955,Q96HY6,Q96DH6,Q9UEY8 42 +Regulated proteolysis of p75ntr 0.9137599560560276 2.352894295592957 0.018627928624777 0.9999999999968836 0.1988390260023547 2 P78536 1 +Glycerophospholipid biosynthesis 0.5531033864784949 2.3491205701987092 0.0188178122374707 0.9999999999976272 0.1993556198691445 35 Q8N2A8,Q9HCL2,Q8IV08,Q9NPH0,P35790,Q8NCC3 6 +Sema4d induced cell migration and growth cone collapse 0.9095723660351348 2.3146130077827265 0.0206341203596873 0.9999999999998256 0.2053134252029987 6 P35579,Q7Z406,O75116,P35580 4 +Sting mediated induction of host immune responses 0.907799790710515 2.307641176536473 0.0210191022994279 0.9999999999998996 0.2053134252029987 6 P19474 1 +Trans golgi network vesicle budding 0.5235469312080557 2.296564553952842 0.0216436226521594 0.9999999999999593 0.2053134252029987 42 P11717,P20645,P51809,P02786,Q9Y5X1,P15586,O43493,O75976,Q99523,O14976,Q9H3P7,P05067 12 +Rhoa gtpase cycle 0.483322104535842 2.249598224187769 0.0244744612896241 0.9999999999999992 0.2239254282927301 52 P41440,O15173,P02786,Q86VI3,Q86UP2,Q07960,Q13464,P30519,O75116,O75955,Q96HY6,Q92888,P11274,Q8NBN3 14 +Interferon gamma signaling 0.7028863558819243 2.2326114312100387 0.0255745796157034 1.0 0.2295211812077193 14 P19474,O15344,P10321,Q13555,P30511,P29372 6 +Sulfide oxidation to sulfate 0.8851963746223558 2.232608820691713 0.0255747519159772 1.0 0.2295211812077193 2 Q9UBX3 1 +Cell surface interactions at the vascular wall 0.6215968879431166 2.22676535173719 0.0259629601747886 1.0 0.2315304486473237 19 Q92896,P53985,P14174 3 +Neutrophil degranulation 0.3984419012949047 2.2055259083939607 0.0274172118039781 1.0 0.2412346160792687 184 P42785,P78371,P84095,P20618,P30519,P14174,Q8N2G8,P10253,P06280,P16278,P11717,O00231,Q8WVQ1,Q07065,O75787,P15586,Q92542,P10619,Q13813,O00754,P07602,O15078,Q13464,Q93050,P12956,Q7L576,P04066,O00584,P61916,O15260,Q9BTY2,P15291,O43681,Q99436,Q9NQX7 35 +Dopamine neurotransmitter release cycle 0.877506179620982 2.1999829566830233 0.0278081042591282 1.0 0.2412346160792687 2 Q13136 1 +Iron uptake and transport 0.6182737263675876 2.19092325910838 0.0284573462763764 1.0 0.2417160153361064 18 Q9Y487,P30519 2 +Synthesis of pa 0.7421836129140272 2.176066427081571 0.0295502938703011 1.0 0.2449197886073785 10 Q8N2A8,Q9HCL2 2 +Mitochondrial calcium ion transport 0.6096223989015555 2.15378469784025 0.0312570602831141 1.0 0.2463338937730985 19 P21796,Q9NWR8,Q9H4I9,P45880,Q9Y4W6,Q8IYU8,Q9BPX6,Q9H300 8 +Egr2 and sox10 mediated initiation of schwann cell myelination 0.7921620588810574 2.1373143376178345 0.032572433478855 1.0 0.2463338937730985 8 Q9NR77,P07942,Q16850 3 +G alpha i signalling events 0.5876553193783202 2.1365145357425654 0.0326374974611436 1.0 0.2463338937730985 25 P07602,P05067,P22466,O43865 4 +Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.7033632514196295 2.088562473645937 0.0367471261755241 1.0 0.2601844260367511 12 P46379,P05067 2 +Keratan sulfate biosynthesis 0.9442307692307694 2.0479833103329694 0.0405616347580397 1.0 0.278787040849161 3 P15291,O60512 2 +Recruitment of mitotic centrosome proteins and complexes 0.5006947966400525 2.02733700739767 0.0426279592826801 1.0 0.2887636234866795 39 Q96CW5,O15078,O94927,Q14203,Q96CS2,Q9H6D7,O75935,O95684,Q9BSJ2,O43805,Q9UPN4 11 +Akt phosphorylates targets in the nucleus 0.8338368580060412 2.012838639472091 0.0441316075126758 1.0 0.2933086555913221 2 P31751 1 +Runx2 regulates genes involved in cell migration 0.8338368580060412 2.012838639472091 0.0441316075126758 1.0 0.2933086555913221 2 P31751 1 +Interferon alpha beta signaling 0.6923349325110644 1.9832568378561 0.0473387479774429 1.0 0.3102339344196146 11 Q13325,P10321,P30511,P42224,P04439 5 +Ptk6 regulates proteins involved in rna processing 0.8242241142543245 1.971230920819456 0.048697468648974 1.0 0.3147464831486443 2 P23246 1 +Heme biosynthesis 0.8207927258683532 1.9588093666949096 0.0501351162381054 1.0 0.3181999044121194 6 P22830,Q7KZN9 2 +Cation coupled chloride cotransporters 0.8170832188959074 1.94023066607398 0.052351663226561 1.0 0.324915137100924 2 P55011 1 +Rhobtb1 gtpase cycle 0.5676692265264504 1.9079948812547851 0.0563918778670116 1.0 0.3381113017643377 20 P78371,P08670,Q13464,O75116,Q9BT78 5 +Rac2 gtpase cycle 0.4806868487017958 1.8856555375987565 0.0593413881230964 1.0 0.3498410705667065 40 Q86XL3,Q13505,Q8TAA9,P02786,Q07960,Q14739,P42166,P49257,Q9Y6W5,Q9NSV4,O15173,Q96RT1,Q9Y2U8,Q7L576,P11274,Q14185,P46940,P50402,Q8IZP0,Q9Y512 20 +Negative regulation of nmda receptor mediated neuronal transmission 0.7574882645266247 1.8761338420005471 0.0606369037182854 1.0 0.353047096442414 7 Q13555,Q14168,P07196 3 +Rho gtpases activate ktn1 0.7558428377608186 1.8690367878234857 0.0616176963957766 1.0 0.3543646294761195 7 P84095,Q86UP2 2 +Recruitment of numa to mitotic centrosomes 0.4716206297006283 1.8592067564136032 0.0629978375102615 1.0 0.3574814032111283 42 Q96CW5,O15078,O94927,Q14203,Q96CS2,Q9H6D7,O75935,O95684,Q9BSJ2,O43805,Q9UPN4 11 +Regulation of innate immune responses to cytosolic dna 0.8689941366240787 1.849869225975036 0.0643324002987268 1.0 0.3619018049254475 4 P19474 1 +Protein localization 0.4132753398318184 1.835698137465017 0.0664023135818063 1.0 0.3683498418770282 83 Q9NR77,P21796,P46379,P25705,Q13505,O75431,O43681,O15254,P05067 9 +Mitotic prometaphase 0.3998058499234651 1.818806151931006 0.0689410095076343 1.0 0.3773159471879463 108 Q8NBT2,P06493,Q96EE3,Q6P1K2,Q8N3U4,Q8WVM7,Q9H6D7,O95347,Q9NTJ3,Q12834,P50748,Q9Y6D9,Q9NTI5,O60566,Q96CW5,Q9H3R5,P57740,Q14203,O75935,Q9NXR1,Q15021,O43805,O15078,Q13362,Q8NFH4,P55735,Q96EA4,Q29RF7,P49792,Q15691,Q9UQE7,O94927,Q96CS2,Q96IY1,Q9HC35,O95684,Q9BSJ2,Q2NKX8,Q9UPN4,Q9BV73,Q9BS16,Q14738 42 +Aurka activation by tpx2 0.475172745102103 1.8163357064500785 0.0693188911238049 1.0 0.3773159471879463 39 O75330,O15078,O94927,Q14203,Q96CS2,Q9H6D7,O75935,O95684,O43805,Q9UPN4 10 +Cytosolic sensors of pathogen associated dna 0.5532392135153372 1.8160833976077024 0.0693575800721633 1.0 0.3773159471879463 20 P12956,P19474 2 +Endosomal vacuolar pathway 0.8200549189438319 1.800239209847666 0.0718228750461065 1.0 0.3847849085169736 5 Q9UIQ6,P30511,P10321 3 +Synthesis of pe 0.8553112521690822 1.7967597739902184 0.0723737649694507 1.0 0.3854510941714627 4 P35790 1 +Transport of inorganic cations anions and amino acids oligopeptides 0.644884852028397 1.7923462739663747 0.0730775151819647 1.0 0.3869804347150528 12 Q70HW3,P55011,Q9UBX3,Q01650,Q15758,P30825,Q9Y666,Q9Y6M7 8 +Sphingolipid metabolism 0.5152798728166976 1.7907633318689682 0.073331281809027 1.0 0.3869804347150528 29 P16278,P07602,P10619,O43681,Q9NRA0,Q96G23,P06280 7 +Response to elevated platelet cytosolic ca2 0.4732351449231141 1.778684228419079 0.0752915463193564 1.0 0.3914604751438125 38 Q9NUQ9,P12814,Q08380,P07602,Q06481,Q8NBX0,P05067 7 +Hs gag degradation 0.8722527472527477 1.7728239929048424 0.076257876395632 1.0 0.3950270141229617 3 P16278,P54802 2 +Constitutive signaling by aberrant pi3k in cancer 0.7751678798434339 1.7709516032061 0.0765687500529983 1.0 0.3951845011892845 6 P84095 1 +Retrograde transport at the trans golgi network 0.5347903580773788 1.763057043348102 0.0778908692692306 1.0 0.3976385318853113 24 P11717,O60499,P20645,Q96CN9,Q8IWJ2,Q96JB2,O43493,O43752 8 +Synthesis of pg 0.8449424120295955 1.7563685397907145 0.0790255010392619 1.0 0.3997945906855631 4 Q8N2A8 1 +Mucopolysaccharidoses 0.8026388125343465 1.730340372010402 0.0835694804801168 1.0 0.4117111818058901 5 P16278,P08236,P15586,P54802 4 +Glycosphingolipid metabolism 0.5433974932333315 1.728357751741559 0.0839241049865733 1.0 0.4120176443417485 18 P16278,P07602,O43681,P10619,P06280 5 +Role of phospholipids in phagocytosis 0.8373377148272607 1.7266688160384007 0.084227159183809 1.0 0.4120696780902326 4 O43865 1 +Rho gtpases activate rocks 0.6486497895824906 1.7237337012482574 0.0847559281013783 1.0 0.4132218086326715 10 P35579,Q7Z406,O75116,P35580 4 +Transcriptional regulation by runx3 0.4556236092947974 1.72102697603961 0.0852459288923239 1.0 0.4141776338251188 42 P28070,P28074,P20618,P49721,Q13573,P28072,Q99436,P60900 8 +Insulin receptor recycling 0.6463603989602489 1.712410802546923 0.0868209896906204 1.0 0.4179623405506146 10 Q9Y487 1 +Extracellular matrix organization 0.4740185318419082 1.712039437594212 0.0868894008873888 1.0 0.4179623405506146 34 P07942,P12814,O75718,P05067,O15484,P78536,Q9BX67,Q92542,P55081,O14936 10 +Signaling by notch4 0.4454278658926001 1.711901572091906 0.0869148089292619 1.0 0.4179623405506146 45 O00231,P28070,P28074,P20618,P49721,Q13573,P28072,Q99436,P60900 9 +Ros and rns production in phagocytes 0.6707466879574591 1.7080320209773714 0.0876304011018394 1.0 0.4199701875935092 9 Q9Y487 1 +Depolymerisation of the nuclear lamina 0.6937474284208482 1.699483021824801 0.0892282108975501 1.0 0.4233082463119468 8 P20700,P06493,Q9Y2U8,P02545,P42166 5 +Establishment of sister chromatid cohesion 0.6916775510112076 1.690082597282644 0.0910121537631019 1.0 0.4260336367183076 8 Q9UQE7,Q8WVM7,Q8N3U4,Q29RF7,Q9NTI5 5 +Diseases of carbohydrate metabolism 0.6397561372889564 1.6796865657797515 0.0930183149696657 1.0 0.4325505141658713 10 P16278,P15586,P08236,P10253,P54802,P13807 6 +Anchoring of the basal body to the plasma membrane 0.4553240590172369 1.6711755590446122 0.0946870063503093 1.0 0.4333810450532794 40 Q15051,O15078,O94927,Q14203,Q96CS2,Q9H6D7,O75935,O95684,O43805,Q9UPN4 10 +Traf6 mediated nf kb activation 0.750608305640588 1.6685765812671745 0.0952013232387958 1.0 0.4333810450532794 6 P05067 1 +Ras activation upon ca2 influx through nmda receptor 0.7867572398725655 1.6662804832953022 0.0956575621089921 1.0 0.4333810450532794 5 Q13555,P07196 2 +Long term potentiation 0.7867572398725655 1.6662804832953022 0.0956575621089921 1.0 0.4333810450532794 5 Q13555,P07196 2 +Unblocking of nmda receptors glutamate binding and activation 0.7867572398725655 1.6662804832953022 0.0956575621089921 1.0 0.4333810450532794 5 Q13555,P07196 2 +Ub specific processing proteases 0.3983319017778551 1.6599333914390728 0.0969278531007735 1.0 0.4349405892324521 80 P21796,P28070,P28074,P20618,P45880,Q14457,Q12834,P28072,Q99436,P60900,Q9UPT9,P49721 12 +Striated muscle contraction 0.7465241823401433 1.651475229108511 0.098641574714533 1.0 0.4370628263294876 6 P08670,P67936,P09493 3 +Lysosome vesicle biogenesis 0.529379951710361 1.639472221585634 0.1011149512926363 1.0 0.4398289345675676 18 P05067 1 +Abc family proteins mediated transport 0.4145790090007246 1.6324014832070133 0.1025949368948637 1.0 0.4447885110303478 57 P28070,P28074,P20618,P49721,O75027,P28072,Q99436,P60900 8 +Abc transporter disorders 0.4295990889714939 1.6270676406823188 0.1037227327324308 1.0 0.4464821840667416 47 P28070,P28074,P20618,O14678,P49721,P28072,Q99436,Q9NUN5,P60900 9 +G beta gamma signalling through pi3kgamma 0.8340659340659343 1.6245768234870177 0.1042527588233526 1.0 0.4464821840667416 3 P31751,Q9UBI6 2 +G protein beta gamma signalling 0.7764310312598505 1.6244771415482366 0.1042740150356162 1.0 0.4464821840667416 5 P31751,Q9UBI6 2 +Uch proteinases 0.4220344431969196 1.620483852556671 0.105128380229033 1.0 0.4464821840667416 49 Q8NB78,Q99436,P28070,P28074,P20618,P49721,P28072,Q9H981,P60900 9 +Muscle contraction 0.5018612430932673 1.6201328091172744 0.1052037509653358 1.0 0.4464821840667416 27 P08670,Q13555,P16615,O43865,P67936 5 +N glycan antennae elongation in the medial trans golgi 0.8098073465729148 1.6186534844156086 0.1055218404346867 1.0 0.4464873068242449 4 P15291,O60512 2 +Cd163 mediating an anti inflammatory response 0.8317624028361741 1.615593097128763 0.1061823173414779 1.0 0.4479367818387499 3 P78536 1 +Antigen processing cross presentation 0.4121212034298975 1.598607608670995 0.1099078180486934 1.0 0.4588775282970145 56 Q9UIQ6,P28070,P28074,P30511,P20618,P49721,P28072,Q99436,P60900 9 +Mrna editing 0.7388080197747844 1.5959365681429654 0.1105029561208377 1.0 0.459288097859175 2 P55265 1 +Phospholipid metabolism 0.4145860684567736 1.5938665625186357 0.1109659250872918 1.0 0.4598558483764536 52 Q8N2A8,Q9HCL2,Q8IV08,Q9NPH0,P35790,Q8NCC3 6 +Leishmania infection 0.4451023081201664 1.5837605710340084 0.1132482150837037 1.0 0.4679376394514328 40 P35579,Q96JJ3,Q96F07,O43865,P78536,Q9UQB8,P05067,Q14185 8 +Keratan sulfate keratin metabolism 0.6676259809207372 1.580355398988831 0.1140254995439056 1.0 0.469771721805155 8 P16278,P15291,O60512,O43505 4 +Rho gtpases activate cit 0.6403565751297481 1.5633375921457962 0.117973210665834 1.0 0.4813530025262612 9 P35579,Q7Z406,P35580 3 +Synthesis of pc 0.6834359408160388 1.5524144933718829 0.1205630777606701 1.0 0.4830424991779874 7 P35790 1 +Organelle biogenesis and maintenance 0.3762151984699837 1.534334403178277 0.1249474062241029 1.0 0.4960999896701757 110 P54619,P78371,Q9Y496,Q9H6D7,Q13505,Q9Y366,A6NIH7,Q14203,O00411,O75935,Q96RR1,O43805,O15078,P00846,O75431,O75964,P48735,Q9NX63,Q15051,O94927,Q96CS2,P25705,O95684,Q96RK4,Q9UPN4,A0AVF1 26 +Sialic acid metabolism 0.7883895292179743 1.5341479670984184 0.1249932550269072 1.0 0.4960999896701757 4 P10619 1 +Cdc42 gtpase cycle 0.4435320383350818 1.5304698240145735 0.1259004772586214 1.0 0.4965971011371589 38 P02786,Q86VI3,Q86UP2,Q07960,Q96RU3,Q96N67,Q9Y5S2,Q9UQB8,P11274 9 +Signaling by notch1 pest domain mutants in cancer 0.6555150146691382 1.5247845838181242 0.1273128362975168 1.0 0.4965971011371589 8 P78536,Q13573 2 +Anti inflammatory response favouring leishmania parasite infection 0.5847739868683602 1.523449844066754 0.1276461998733427 1.0 0.4965971011371589 13 P35579,P78536,O43865 3 +Interleukin 1 signaling 0.4083002959660308 1.5223302987353666 0.1279263398960344 1.0 0.4965971011371589 50 P28070,P28074,P20618,P49721,P28072,Q99436,P60900,P05067 8 +Signaling by vegf 0.4621169737824291 1.5197876130759944 0.1285643633058548 1.0 0.4965971011371589 32 P35221,Q96JJ3,Q13464,O75116,Q96F07,P31751,O43865,Q9Y6W5,Q7L576,Q9UQB8,Q14185 11 +Nuclear signaling by erbb4 0.7815277201981253 1.5070007709145627 0.1318104595992677 1.0 0.5019484799334277 4 P78536,Q92542 2 +Semaphorin interactions 0.5050379492601332 1.503699874732771 0.1326586615066369 1.0 0.5026757803609405 20 P35579,P35580,Q7Z406,Q13464,O75116 5 +Deubiquitination 0.3801064986591763 1.4947549509485356 0.1349784072484066 1.0 0.5050165315266305 98 Q99436,P21796,Q8NB78,P28070,P28074,P20618,P45880,Q14457,Q12834,P28072,Q9H981,P60900,Q9UPT9,P49721 14 +Protein protein interactions at synapses 0.5347532947235073 1.478471766351771 0.139281548722375 1.0 0.508687261711124 16 Q13136,Q14168,O75955,P10586,P41440 5 +Slc mediated transmembrane transport 0.4812563951202303 1.47322049497986 0.1406915904720787 1.0 0.508687261711124 27 P11166,O00400,Q70HW3,P55011,Q9UBX3,P53985,Q8TB61,Q01650,Q15758,P30825,Q9Y666,Q9Y6M7 12 +Ptk6 regulates cell cycle 0.7107937379840668 1.471204442464751 0.1412358361433638 1.0 0.508687261711124 2 P11802 1 +Runx1 regulates expression of components of tight junctions 0.7096951386981564 1.4663034167091515 0.1425656450780796 1.0 0.508687261711124 2 Q16625 1 +Transferrin endocytosis and recycling 0.5896181643036278 1.4647022691928713 0.1430021655731801 1.0 0.508687261711124 11 Q9Y487 1 +Rac3 gtpase cycle 0.43570762121149 1.4644156864257838 0.1430804046742544 1.0 0.508687261711124 38 Q8TAA9,O15173,Q96RT1,P02786,Q7L576,Q96AC1,Q07960,Q9Y2U8,P50402,Q14739,Q8IZP0,P42166,P49257,Q15758,Q9Y6W5,Q9NSV4,Q9UQB8,P11274 18 +Bile acid and bile salt metabolism 0.6630989287022068 1.4621912534852473 0.1436888077792955 1.0 0.508687261711124 7 Q9H4L5 1 +Synthesis of bile acids and bile salts 0.6630989287022068 1.4621912534852473 0.1436888077792955 1.0 0.508687261711124 7 Q9H4L5 1 +Signaling by notch 0.3889877961812142 1.4599059284750031 0.1443159296740999 1.0 0.5096269296010194 65 O00231,P28070,P28074,P16615,P20618,P15291,P49721,Q13573,P28072,P78536,Q99436,P60900 12 +Defects in cobalamin b12 metabolism 0.6997986488424472 1.454496081970679 0.1458088189480872 1.0 0.5110939195826233 6 O14678,Q9NUN5 2 +Rac1 gtpase cycle 0.4025952610446692 1.4343441081449102 0.1514740889994001 1.0 0.5151115390747943 49 Q86VI3,Q96N67,Q9UQB8,Q8TAA9,P02786,Q86UP2,Q07960,A1A4S6,Q14739,P42166,Q15758,Q9Y6W5,Q9NSV4,Q96RT1,Q9Y2U8,Q96F07,Q16513,Q7L576,P11274,Q14185,P46940,Q96AC1,P50402 23 +Pyruvate metabolism 0.4972549461433415 1.4334911366819336 0.1517175300685638 1.0 0.5151115390747943 18 P21796,P53985 2 +Interleukin 1 family signaling 0.3976497455412544 1.4327082048049409 0.1519412437509828 1.0 0.5151115390747943 53 P28070,P28074,P20618,P49721,P28072,Q99436,P60900,P05067 8 +Cobalamin cbl vitamin b12 transport and metabolism 0.655969918465476 1.4304632579957646 0.1525841038476008 1.0 0.5151115390747943 7 O14678,Q9NUN5 2 +Regulation of runx3 expression and activity 0.43168539375335 1.430369180991426 0.152611088735699 1.0 0.5151115390747943 38 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Vitamin d calciferol metabolism 0.761747732893653 1.4285856309837053 0.1531233665080429 1.0 0.5151115390747943 4 Q99538,P04062,P61956 3 +Synthesis of pips at the er membrane 0.7006316945893947 1.4258514283420645 0.1539112322824471 1.0 0.5163355387761145 2 P42356 1 +Sphingolipid de novo biosynthesis 0.5815293257623171 1.4229959595544683 0.1547373265351646 1.0 0.5166466660854192 11 Q96G23,Q9NRA0,P27544,O95470 4 +Signaling by ptk6 0.5720276768120638 1.4121630810316927 0.1579019483309243 1.0 0.5234914004665231 12 Q96JJ3,Q14185,P23246,P31749 4 +Fcgamma receptor fcgr dependent phagocytosis 0.452515526834454 1.40295424345143 0.1606304839175389 1.0 0.5306070792387101 31 P35579,Q8IV08,Q96JJ3,Q96F07,O43865,Q9UQB8,Q14185 7 +Hedgehog ligand biogenesis 0.4163533305838872 1.3986059266142614 0.1619311881282081 1.0 0.5306070792387101 43 P28070,P28074,P20618,P49721,P28072,P78536,Q99436,P60900 8 +P38mapk events 0.6912936006591556 1.3841487243057615 0.1663129201595241 1.0 0.5387009298960219 2 P11233 1 +Apoptotic cleavage of cellular proteins 0.4874453546782576 1.378322051647293 0.1681038777488823 1.0 0.5420099856937649 19 P20700,P49354,P08670,P02545,Q13813 5 +Ptk6 regulates rho gtpases ras gtpase and map kinases 0.7481473453302415 1.3745635390460291 0.1692667989121492 1.0 0.543273165528971 4 Q14185 1 +Rho gtpases activate paks 0.5637130486144935 1.3681768831969845 0.1712567156671252 1.0 0.5471671482425836 12 P35579,P35580 2 +Flt3 signaling 0.7118926763273399 1.3611058680081356 0.1734802355260993 1.0 0.5500030935634845 5 P31751 1 +Scf skp2 mediated degradation of p27 p21 0.4141937487992558 1.3570102248163545 0.1747779616859388 1.0 0.5500030935634845 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Degradation of axin 0.4229284073509924 1.356058835164719 0.1750804490244601 1.0 0.5500030935634845 38 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Cross presentation of soluble exogenous antigens endosomes 0.4229284073509924 1.356058835164719 0.1750804490244601 1.0 0.5500030935634845 38 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Ecm proteoglycans 0.6764449758842264 1.3553394645904489 0.1753094268575656 1.0 0.5500030935634845 6 P05067 1 +Degradation of dvl 0.4183754061395408 1.353043323720051 0.1760417902106423 1.0 0.5500030935634845 40 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Amino acid transport across the plasma membrane 0.7098254234071115 1.3526282336772435 0.1761744279699977 1.0 0.5500030935634845 5 P30825 1 +Synaptic adhesion like molecules 0.6380992795989883 1.3507467649276974 0.1767765663114737 1.0 0.5500030935634845 7 P41440,P10586 2 +Cristae formation 0.4801444817708108 1.3502671116171472 0.1769303178223298 1.0 0.5500030935634845 21 P00846,Q13505,O75431,O75964 4 +Asymmetric localization of pcp proteins 0.4178120172000624 1.3481528321259333 0.1776092317752913 1.0 0.5500030935634845 40 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Regulation of ras by gaps 0.4194880012154608 1.3441067667422866 0.1789138642616921 1.0 0.5528281463700091 39 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Miscellaneous transport and binding events 0.6124389028637427 1.3257966473907836 0.1849070638183945 1.0 0.5607944737673562 8 Q9UNS2,Q8N4V1,Q9HD23,Q9UEY8 4 +Rhobtb gtpase cycle 0.4462305734244962 1.3167175597412364 0.1879333153947016 1.0 0.5648036813435443 30 P12814,P78371,P08670,Q13464,P61201,O75116,Q9BT78 7 +Sulfur amino acid metabolism 0.5536492599861192 1.314827988450201 0.1885677187833467 1.0 0.5653019484377354 12 P32929,Q13126,Q9UBX3 3 +Signaling by erbb4 0.628704702716328 1.3087593464295686 0.1906158817973287 1.0 0.5696772966939541 7 P78536,Q92542 2 +Glycosaminoglycan metabolism 0.4727373110966191 1.300734329801189 0.1933494071588457 1.0 0.5728352077329196 21 P16278,Q8NCH0,O75330,Q96L58,P15586,O43505,P15291,P08236,O60512,P54802 10 +Mitotic g2 g2 m phases 0.3648623281963331 1.3002365299104115 0.1935199140389423 1.0 0.5728352077329196 97 P20618,Q9H6D7,P28072,Q9UL46,P60900,O00231,O75330,Q96CW5,P28070,P28074,Q14203,O75935,O43805,P49721,O15078,O94927,Q96CS2,O95684,Q9BSJ2,Q99436,Q9UPN4 21 +Assembly and cell surface presentation of nmda receptors 0.5568140736122038 1.2950636584836963 0.1952982702530188 1.0 0.5768873433679319 11 Q13555,Q14168,P07196 3 +Regulation of tp53 activity through association with co factors 0.7496464839756442 1.293477410685889 0.1958459919142847 1.0 0.5772949845339481 3 P31751 1 +Clec7a dectin 1 signaling 0.384303995056532 1.2913500802924702 0.1965823122517709 1.0 0.5782556951205537 51 P28070,P28074,P20618,P49721,O43865,P28072,Q99436,P60900 8 +Biological oxidations 0.3904435705410201 1.2877862112060592 0.1978203934665106 1.0 0.580685279988153 48 Q16850,P30837,Q9NX62,P07099,Q6N069 5 +Auf1 hnrnp d0 binds and destabilizes mrna 0.4057952849669197 1.2824168856323062 0.1996964439196507 1.0 0.5825513239809271 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Myogenesis 0.6576103249257903 1.275182586015459 0.2022446234667754 1.0 0.5851389619398081 6 P19022,P35222,Q16539,P35221 4 +Negative regulation of notch4 signaling 0.4046948643687307 1.272630765799501 0.2031490959665411 1.0 0.5865513856902798 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Purine salvage 0.6193052684406963 1.2667145154979325 0.2052573878505827 1.0 0.588764983910554 7 P00813 1 +Cdt1 association with the cdc6 orc origin complex 0.4037435536908513 1.2641687440226592 0.206169466812456 1.0 0.588764983910554 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Dag and ip3 signaling 0.5990064340884997 1.2634627495805208 0.2064229255158365 1.0 0.588764983910554 8 O43865 1 +Class i mhc mediated antigen processing presentation 0.3423097744820485 1.2611885963846992 0.2072409062331697 1.0 0.5899039128940124 126 P19474,P52888,Q9UIQ6,P28070,P28074,P55735,P30511,P20618,Q9NZ08,Q12834,P28072,Q99436,P60900,Q13049,P49721,P55786 16 +Transcriptional regulation by runx1 0.3624831549962155 1.257191137192634 0.2086844318037126 1.0 0.5902104267109028 72 Q9HCL2,P28070,P28074,P20618,P49721,P28072,Q99436,P60900 8 +Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.4564200643956041 1.2416195215936383 0.2143769756460807 1.0 0.5981329874956984 25 P14174 1 +Rhog gtpase cycle 0.4048954083785452 1.2358238580295011 0.2165240446530254 1.0 0.6018243895728522 40 Q86XL3,Q8TAA9,O15173,Q96RT1,P84095,P02786,Q86UP2,Q96JJ3,Q07960,Q9Y2U8,Q14739,P50402,P42166,P49257,Q7L576,Q14185 16 +Signaling by cytosolic fgfr1 fusion mutants 0.5707883067141906 1.2274841426805767 0.2196406782443656 1.0 0.6018243895728522 9 P11274,Q9UBW7 2 +Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.6779462699441419 1.2218093183327672 0.2217797438945545 1.0 0.6018243895728522 5 Q8NB78,Q9HCE1 2 +Processing of smdt1 0.5172706916899845 1.22176498937454 0.2217965117698459 1.0 0.6018243895728522 14 Q9NWR8,Q9H4I9,Q9Y4W6,Q9BPX6,Q9H300,Q8IYU8 6 +Cilium assembly 0.3598231001580724 1.22135556273089 0.2219514244567089 1.0 0.6018243895728522 74 Q15051,P78371,Q9Y496,O15078,O94927,A6NIH7,Q14203,Q9H6D7,Q96CS2,O75935,O95684,Q96RK4,Q9Y366,O43805,Q9UPN4,A0AVF1 16 +Initiation of nuclear envelope ne reformation 0.4917673432017568 1.2203142247166936 0.2223457794366521 1.0 0.6018243895728522 16 P20700,Q86XL3,P06493,Q9Y2U8,Q14739,P02545,P42166 7 +Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3764994170929603 1.217730203688732 0.223326515334302 1.0 0.6018243895728522 52 P28070,P28074,P20618,P49721,Q12834,P28072,Q99436,P60900 8 +Cardiac conduction 0.5416437287889481 1.2162856531661144 0.2238761248394396 1.0 0.6018243895728522 11 Q13555,O43865 2 +Ion homeostasis 0.5416437287889481 1.2162856531661144 0.2238761248394396 1.0 0.6018243895728522 11 Q13555,O43865 2 +Rhob gtpase cycle 0.441144324092714 1.2126920160675714 0.2252475934541902 1.0 0.6018243895728522 28 P41440,Q86VI3,Q07960,Q13464,O75116,O75955,Q92888,P11274 8 +Diseases of signal transduction by growth factor receptors and second messengers 0.3217615829092076 1.211969717327694 0.2255239728136735 1.0 0.6018243895728522 153 P26038,Q9P2E9,P51114,P84095,P20618,P02545,P06753,O00291,P28072,P60900,P35579,O00231,P28070,P28074,Q14203,P67936,Q92542,P49721,P33176,P48729,Q9NRY5,Q8IWJ2,Q13573,P78536,P11274,Q96PU8,Q13555,Q9NWH9,Q6WCQ1,Q01082,P31751,O95684,Q99436,Q9UBW7 34 +Golgi associated vesicle biogenesis 0.4171875388706277 1.2070287426309845 0.2274210749743566 1.0 0.6056420085340792 33 P11717,P51809,P02786,Q9Y5X1,O75976,O43493,Q99523,O14976,Q9H3P7 9 +Regulation of plk1 activity at g2 m transition 0.3971955326802331 1.2058827019571765 0.2278627212834099 1.0 0.6056420085340792 42 O15078,O94927,Q14203,Q96CS2,Q9H6D7,O75935,O95684,O43805,Q9UPN4 9 +Stabilization of p53 0.3991151587712179 1.2035532492190502 0.2287622983183517 1.0 0.6056420085340792 41 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Mitochondrial biogenesis 0.408241187411757 1.2019048075434453 0.2294004115978549 1.0 0.6056420085340792 36 P00846,P25705,O00411,Q13505,O75431,O75964,Q96RR1,P48735 8 +Rhoh gtpase cycle 0.4497642665207832 1.1949507113843394 0.2321062879652737 1.0 0.6096380748705109 25 P27105,P02786,Q13464,O75116,Q9BXS4,Q15758,Q9Y6M7 7 +Metabolism of polyamines 0.399956227231313 1.192794681044436 0.2329497937218505 1.0 0.6099951145601871 40 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +G1 s dna damage checkpoints 0.3950691743662881 1.1869437558337588 0.2352498064717278 1.0 0.6119891329199174 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Immunoregulatory interactions between a lymphoid and a non lymphoid cell 0.6010456875373341 1.1850012226397733 0.2360169634985816 1.0 0.6119891329199174 7 Q5KU26,P30511,P10321 3 +Antigen processing ubiquitination proteasome degradation 0.35493549666787 1.1803318576698496 0.2378682522494368 1.0 0.6138395007682353 98 P19474,P52888,Q9UIQ6,P28070,P28074,P20618,Q12834,P28072,Q99436,P60900,Q13049,P49721,P55786 13 +Cyclin a cdk2 associated events at s phase entry 0.3869932485982776 1.178056240216128 0.2387741859560623 1.0 0.6150508738795099 45 O00231,P28070,P28074,P20618,P49721,P28072,Q99436,P60900 8 +Interaction between l1 and ankyrins 0.6983487726092241 1.1766076625837092 0.2393521379617231 1.0 0.6151096101550397 4 Q13813 1 +N glycan trimming and elongation in the cis golgi 0.6981482489335331 1.1758117659535792 0.2396701036019282 1.0 0.6151096101550397 4 O60476 1 +Regulation of runx2 expression and activity 0.3885732158414541 1.1699946308999845 0.2420031295200937 1.0 0.6181396808981735 44 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Regulation of pten stability and activity 0.3860069741387525 1.1689593351885448 0.2424200155326585 1.0 0.6181396808981735 45 O00231,P28070,P28074,P20618,P31751,P49721,P28072,Q99436,P60900 9 +Tnfr2 non canonical nf kb pathway 0.3899805348719883 1.161508442131581 0.2454351920230606 1.0 0.6181396808981735 43 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Dectin 1 mediated noncanonical nf kb signaling 0.3899805348719883 1.161508442131581 0.2454351920230606 1.0 0.6181396808981735 43 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Fc epsilon receptor fceri signaling 0.3693824471326972 1.1597391906103025 0.2461550088249797 1.0 0.6181396808981735 55 P28070,P28074,P20618,P49721,O43865,P28072,Q99436,P60900 8 +Signaling by the b cell receptor bcr 0.3770289725021871 1.159470222970194 0.2462645672737706 1.0 0.6181396808981735 48 P28070,P28074,P20618,P49721,O43865,P28072,Q99436,P60900 8 +C type lectin receptors clrs 0.3696538598559272 1.157570881213454 0.2470391979936257 1.0 0.6181396808981735 54 P28070,P28074,P20618,P49721,O43865,P28072,Q99436,P60900 8 +Ion transport by p type atpases 0.5299552462229105 1.1555382860021393 0.247870063667472 1.0 0.6181396808981735 11 Q13555,P16615 2 +Mitochondrial protein import 0.3985240542874841 1.1480613211523996 0.2509432501188089 1.0 0.6232135980452779 38 P21796,Q13505,O75431 3 +Mapk6 mapk4 signaling 0.3729216435130343 1.147363065119281 0.2512315994958962 1.0 0.6232135980452779 49 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Rhoc gtpase cycle 0.4005929274354854 1.137918169929306 0.2551546533579243 1.0 0.6262054432761311 36 P46940,P27105,Q8TAA9,P41440,Q96RT1,P02786,Q86VI3,Q07960,Q13464,Q14739,O75116,P42166,P49257,O75955,Q16513,Q92888,P11274 17 +Basigin interactions 0.5717596419884149 1.136941593345658 0.2555627028475391 1.0 0.6262054432761311 8 P53985 1 +Interleukin 9 signaling 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.6262054432761311 2 P42224 1 +Interleukin 21 signaling 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.6262054432761311 2 P42224 1 +Interleukin 7 signaling 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.6262054432761311 2 P51532 1 +Cytoprotection by hmox1 0.351799456984125 1.1347070183366792 0.2564980957122733 1.0 0.6263532354568339 72 P28070,P28074,P20618,P30519,P49721,P28072,Q99436,P60900 8 +Disorders of transmembrane transporters 0.3532801908744138 1.1328128865438434 0.2572928386637203 1.0 0.6272069371577542 82 P11166,O00231,P28070,P28074,P55735,P53985,P20618,O14678,P28072,Q99436,P60900,Q9NUN5,P49721 13 +Downregulation of erbb2 erbb3 signaling 0.7074175824175832 1.1277641274166883 0.2594195469595324 1.0 0.6278641790604144 3 P31751,P31749 2 +Tp53 regulates transcription of genes involved in g1 cell cycle arrest 0.6336171381488547 1.12704114526228 0.2597250851682369 1.0 0.6278641790604144 2 P24941 1 +Cd28 co stimulation 0.5696101271412796 1.1269677449445454 0.2597561186724582 1.0 0.6278641790604144 8 P42345,P62993,P31751,P63000,Q16512,P31749 6 +Cellular response to chemical stress 0.3526499709983194 1.1253550368871654 0.2604386162689356 1.0 0.6283527574022779 82 Q99436,P28070,P28074,P20618,P30519,P28072,P00390,P60900,P49721 9 +G protein mediated events 0.516282433456632 1.1161788670886896 0.2643455785032487 1.0 0.6308242069956337 12 O43865 1 +Loss of mecp2 binding ability to the ncor smrt complex 0.6308706399340782 1.1148667033004371 0.2649075470732489 1.0 0.6308242069956337 2 Q9BZK7 1 +Degradation of cysteine and homocysteine 0.6193533654117018 1.112380528377981 0.2659745730140819 1.0 0.6308242069956337 6 P32929,Q9UBX3 2 +Nr1h2 and nr1h3 mediated signaling 0.5845838763055293 1.1113946813919733 0.2663985006581688 1.0 0.6308242069956337 7 Q8NB78,Q9HCE1 2 +Ctla4 inhibitory signaling 0.5647898614649776 1.104611279920095 0.2693280612685365 1.0 0.6356503154562276 8 P31751,P31749,Q13362 3 +Defective cftr causes cystic fibrosis 0.3812741075461728 1.103457208955422 0.269828664479272 1.0 0.635766869985442 44 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Glycogen storage diseases 0.7004968725163168 1.10072229430335 0.2710175401351231 1.0 0.6364395234173141 3 P10253 1 +Intra golgi and retrograde golgi to er traffic 0.3438748094092652 1.093811976805795 0.2740374502091349 1.0 0.6418468769461703 108 Q92538,Q9Y496,Q15102,Q8TD16,O43493,O60476,A2RRP1,P11717,P20645,Q10472,Q14203,O75935,P24390,P33176,O60499,O00461,Q8IWJ2,Q96JB2,P52732,Q9Y678,O43752,Q96CN9,P35606,O15260,Q8TBA6 25 +Fgfr1 mutant receptor activation 0.5179894259215363 1.093370314188644 0.2742312419599677 1.0 0.6418468769461703 11 P11274,Q9UBW7 2 +Interleukin 12 family signaling 0.4157372454828029 1.0847774220483355 0.2780202476772224 1.0 0.6423489094413377 30 P14174 1 +Interleukin 12 signaling 0.4268562203827433 1.0807062887596106 0.2798277848011308 1.0 0.6423489094413377 27 P14174 1 +Cd28 dependent pi3k akt signaling 0.695138958330602 1.07982195862421 0.2802214708705524 1.0 0.6423489094413377 3 P31751 1 +Pcp ce pathway 0.3627067658404216 1.0779435485049866 0.2810589494530746 1.0 0.6423489094413377 51 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Notch3 activation and transmission of signal to the nucleus 0.6940954752433972 1.0757554117467747 0.2820366583194875 1.0 0.6423489094413377 3 Q92542 1 +Degradation of gli1 by the proteasome 0.3821772886422747 1.072095011018507 0.2836773594730706 1.0 0.6423489094413377 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Plasma lipoprotein clearance 0.4671957024489656 1.0720146470637972 0.2837134533638421 1.0 0.6423489094413377 16 Q8WTV0,O15118,P61916 3 +Antigen presentation folding assembly and peptide loading of class i mhc 0.4406532585408431 1.0710154877841065 0.2841624658017574 1.0 0.6423489094413377 19 P55735,Q9NZ08,P30511,P10321 4 +The role of gtse1 in g2 m progression after g2 checkpoint 0.3650185270625462 1.0707192438233686 0.2842956873471025 1.0 0.6423489094413377 49 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Downstream signaling events of b cell receptor bcr 0.3752070213317738 1.0693445231961236 0.2849144553148086 1.0 0.6423489094413377 45 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Signaling by notch3 0.6087670035931815 1.067463855748814 0.2857624267329037 1.0 0.6423489094413377 6 Q9Y6A5,Q92542,Q13573 3 +Metabolism of steroids 0.3600101965403084 1.060432833334936 0.2889477316199744 1.0 0.6452097525396894 54 Q16850,Q15392,Q9HCL2,Q9BWD1 4 +Tnf signaling 0.5356589876247528 1.0571088993946662 0.2904618901100653 1.0 0.6467102067552618 9 Q8TCT8 1 +Runx1 regulates transcription of genes involved in differentiation of hscs 0.3797078316229652 1.0501082082430817 0.2936683652929437 1.0 0.6485559979588679 42 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Tryptophan catabolism 0.686158819504952 1.0448714099516765 0.2960824050861368 1.0 0.6493795008570775 3 Q01650 1 +Innate immune system 0.359912243877256 1.0446659556923947 0.2961773846046542 1.0 0.6493795008570775 303 P42785,P84095,P20618,P30519,P14174,P10253,P28072,Q9UQB8,P05067,P06280,P60900,P16278,P11717,P35579,O00231,P19474,Q9Y487,P28074,P28070,Q96JJ3,Q07065,O75787,O43865,Q92542,P10619,P49721,Q13049,Q13813,P07602,Q8IV08,O15078,Q13464,Q96F07,Q93050,P12956,Q7L576,Q14185,P04066,Q15075,O00584,O15260,Q9BTY2,P15291,O43681,Q99436,Q9NQX7 46 +Orc1 removal from chromatin 0.3588101907645629 1.041802677792336 0.297503172399836 1.0 0.6493795008570775 52 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Rhoj gtpase cycle 0.421018091122652 1.0384871930235398 0.299043294639095 1.0 0.6512395705509815 27 P27105,P02786,Q86VI3,Q07960,Q96RU3,Q9Y5S2,Q9Y6M7 7 +Disassembly of the destruction complex and recruitment of axin to the membrane 0.53103767566377 1.0347555044831882 0.3007831075818612 1.0 0.6530098591415139 9 P48729,P35222,Q13362 3 +Fceri mediated nf kb activation 0.3682031232672719 1.02665119083368 0.3045847401276598 1.0 0.6588965941891733 46 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Beta catenin phosphorylation cascade 0.5475888543326376 1.024995871760869 0.3053651355610576 1.0 0.6588965941891733 8 P48729,P35222,Q13362 3 +Signaling by ctnnb1 phospho site mutants 0.5475888543326376 1.024995871760869 0.3053651355610576 1.0 0.6588965941891733 8 P48729,P35222,Q13362 3 +Caspase mediated cleavage of cytoskeletal proteins 0.6274837902592818 1.0155213830046124 0.3098573589203706 1.0 0.6655320407298814 5 P08670 1 +Cytosolic iron sulfur cluster assembly 0.559479247161421 0.9995564167533284 0.3175252237937109 1.0 0.6739308347990902 7 O75027 1 +Interleukin 15 signaling 0.6045042570722265 0.9986578302669502 0.3179604753190546 1.0 0.6739308347990902 2 P40763 1 +Ripk1 mediated regulated necrosis 0.4976688300353443 0.9880499069628412 0.3231282069415129 1.0 0.6812403109903161 11 P41440 1 +Hedgehog on state 0.3685080186711754 0.9872098334904158 0.3235397820888575 1.0 0.6812403109903161 44 O00231,Q9Y496,P28070,P28074,P20618,P49721,P28072,Q99436,P60900 9 +Sensory processing of sound by outer hair cells of the cochlea 0.4744250800649578 0.9807984051408428 0.3266921649071925 1.0 0.6834652013167629 14 P35579,Q01082,Q13813,O14936 4 +Hemostasis 0.3052081786378821 0.9738349892682824 0.3301384771135969 1.0 0.689133502597123 142 Q9NUQ9,P12814,P42785,P07602,Q08380,Q06481,Q92896,P84095,Q8NBX0,P53985,P16615,P52732,P14174,Q01650,P05067,Q14185,P33176 17 +Heparan sulfate heparin hs gag metabolism 0.551993155191936 0.9663711422529844 0.3338584988021575 1.0 0.6948399184818906 7 P16278,Q96L58,P54802 3 +Nucleotide salvage 0.4981584273874748 0.9649113052185764 0.3345892384541398 1.0 0.6953336828641342 10 P00813 1 +Pi3k akt signaling in cancer 0.478914266890346 0.9487455153395687 0.3427500588086931 1.0 0.7023742093337724 13 P84095,P31751,Q9NWH9 3 +Meiotic synapsis 0.4466522356774517 0.9483403678604309 0.3429562065159732 1.0 0.7023742093337724 16 P20700,Q9UQE7,Q9UH99,Q8N3U4,Q8WVM7,P02545,Q9BTC0,Q14683 8 +Signaling by insulin receptor 0.4466503395602457 0.9483289867825794 0.3429619985959087 1.0 0.7023742093337724 16 Q9Y487 1 +Signaling by notch1 0.489757555458453 0.947207227633361 0.3435331931349767 1.0 0.7023868151820889 11 P78536,Q13573 2 +Killing mechanisms 0.592419664927211 0.945921466219917 0.344188643756083 1.0 0.7023868151820889 2 P63000 1 +Regulation of beta cell development 0.6078783569745554 0.9361975153760898 0.3491715022209578 1.0 0.70850675159907 5 P31751,Q13573 2 +Hedgehog off state 0.3475421259129688 0.935088042005999 0.3497429286127476 1.0 0.70850675159907 54 P28070,P28074,P20618,P49721,P28072,Q9Y366,Q99436,P60900 8 +Degradation of beta catenin by the destruction complex 0.3480233375728669 0.934752326154662 0.3499159535782057 1.0 0.70850675159907 52 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Signaling by fgfr1 in disease 0.4806398970331463 0.927274832896192 0.3537838577563805 1.0 0.7128635304296219 12 P11274,Q9UBW7 2 +Potential therapeutics for sars 0.3675299678105562 0.925646605285352 0.354629664794774 1.0 0.7128635304296219 41 O75116,Q99720,P49354 3 +Smooth muscle contraction 0.4733825394127425 0.9188457774078048 0.3581762445578857 1.0 0.7168612621904277 13 P67936,P09493 2 +Signaling by pdgfr in disease 0.6031428884814354 0.9171497211607692 0.3590641894432067 1.0 0.7169142779184623 5 P42224,Q6UN15,P40763 3 +Nonhomologous end joining nhej 0.4413934754994149 0.9168094410202368 0.3592425045220955 1.0 0.7169142779184623 16 P12956 1 +Nef and signal transduction 0.5850041197473151 0.9137713128997303 0.3608370232039166 1.0 0.7169142779184623 2 P63000 1 +Degradation of the extracellular matrix 0.4868691888367816 0.9080952387213512 0.363827905811648 1.0 0.7169142779184623 10 P78536,P07942,Q92542,O15484 4 +Metabolism of lipids 0.3256381979942419 0.9052629804734942 0.365326083424738 1.0 0.7169142779184623 208 Q9HCL2,O43772,Q71SY5,Q8NCC3,Q96G23,Q8N8N7,P06280,P16278,Q15392,P35790,Q9Y6K0,P10619,Q16850,Q8N2A8,P07602,Q8IV08,P50897,P23786,Q9UMR5,Q9BWD1,O15254,Q9H4L5,Q15165,Q9NPH0,O43681 25 +Cell cell junction organization 0.5031240049247572 0.9004623262530352 0.3678742654891227 1.0 0.7199095001030192 9 P35222,Q8N3R9,P35221,Q9BY67 4 +Ion channel transport 0.3908095587369786 0.895683260787061 0.3704219530533663 1.0 0.7211037425403297 30 Q9Y487,Q93050,P16615,Q13555 4 +Vitamin b5 pantothenate metabolism 0.5975480161877234 0.8947113313975757 0.3709414197476224 1.0 0.7211037425403297 5 Q9NVE7 1 +Rhod gtpase cycle 0.3858405998611602 0.8875368962091347 0.3747899108569816 1.0 0.7263809964202024 31 P20700,P12814,Q8TAA9,Q9UEY8,O15173,P50402,Q8NHP6,Q07960,Q9Y2U8,Q14739,P42166,P49257,Q9BX68,Q02952,Q9Y6M7 15 +Regulation of mecp2 expression and activity 0.4822790261801587 0.8850832912555512 0.3761117104751155 1.0 0.7271791186469797 10 Q13555,Q14739 2 +O linked glycosylation 0.5334949945173424 0.884856728353719 0.3762339087960598 1.0 0.7271791186469797 7 Q8NAT1,Q10472,O43505 3 +Downregulation of erbb2 signaling 0.5153224528766659 0.8769124706241818 0.380534182139439 1.0 0.7325043788921449 8 Q96RT1,P31751,Q16543,P31749 4 +Cellular response to hypoxia 0.3583123972943056 0.876885630620516 0.380548761780731 1.0 0.7325043788921449 43 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Fatty acyl coa biosynthesis 0.4330402127738565 0.8668867132920101 0.3860040841841017 1.0 0.7373603888792019 16 P50897 1 +Transcriptional regulation of white adipocyte differentiation 0.4632799938728178 0.8644468652146658 0.3873424574076389 1.0 0.7376584195218688 13 P11802,Q9NVC6,Q9NPJ6,Q71SY5,Q9BZK7,Q9Y2W1 6 +Apc c mediated degradation of cell cycle proteins 0.3382757924732812 0.8626822083834199 0.3883122170799846 1.0 0.7383696543396738 59 P28070,P28074,P20618,P49721,Q12834,P28072,Q99436,P60900 8 +Rnd2 gtpase cycle 0.4067691622153528 0.8492051751525951 0.3957671340954463 1.0 0.7471627262989831 19 Q86UP2,Q96RU3,Q07960,Q07065 4 +Resolution of sister chromatid cohesion 0.3258992467794483 0.8381607748655181 0.4019404137151343 1.0 0.7518583951874754 72 Q8NBT2,P06493,Q96EE3,Q6P1K2,Q8N3U4,Q8WVM7,Q12834,P50748,Q9Y6D9,Q9NTI5,O60566,Q9H3R5,P57740,Q9NXR1,Q8NFH4,Q13362,P55735,Q96EA4,Q29RF7,P49792,Q9UQE7,Q15691,Q96IY1,Q2NKX8,Q9BS16,Q14738 26 +G alpha 12 13 signalling events 0.489890351173375 0.8374441469600443 0.4023429595254482 1.0 0.7518583951874754 9 O75116,Q92888,Q13464 3 +Gap junction degradation 0.5513910622114284 0.8270925374030876 0.4081846136593967 1.0 0.7557478123528032 6 Q00610,Q96CW1 2 +Hdms demethylate histones 0.5039200844112183 0.8252118688131606 0.4092513162676188 1.0 0.7557478123528032 8 Q8NB78 1 +Signaling by nuclear receptors 0.3294375974307611 0.8135265575793494 0.4159162261119173 1.0 0.76152681223333 65 Q8NB78,Q9HCL2,O94788,Q8WVM7,P11177,P31751,Q9UBI6 7 +Transcriptional regulation by mecp2 0.4333291842156635 0.8069725900761175 0.4196822751016857 1.0 0.7649836036458929 15 Q13555,Q9HCE1,Q9NWH9,Q14739 4 +Carnitine metabolism 0.5455688671610739 0.8031618404180144 0.4218811982321124 1.0 0.7675788448972239 6 O43772 1 +Transcriptional regulation by runx2 0.3345120289794788 0.8015223047208181 0.4228293367201523 1.0 0.7675788448972239 52 O00231,P28070,P28074,P20618,P49721,P28072,Q99436,P60900 8 +Intra golgi traffic 0.3976084885281818 0.798478483069554 0.4245928747603167 1.0 0.7689606176571803 21 Q9Y2V7,O00461,Q96JB2,O60476,O43752,Q8TBA6 6 +Signaling by hedgehog 0.328874690303414 0.7835740360207363 0.4332900956745003 1.0 0.7788792035712603 62 P28070,P28074,P20618,P49721,P28072,Q9Y366,Q99436,P60900,P78536 9 +Inactivation of cdc42 and rac1 0.6171294649722465 0.7816542871834326 0.4344177734908305 1.0 0.7788792035712603 3 O94813 1 +Intracellular signaling by second messengers 0.3235976343823825 0.7815282357379332 0.4344918765131373 1.0 0.7788792035712603 95 P84095,P20618,P14373,P28072,Q9UL46,P60900,O00231,P28070,P28074,O43865,P49721,Q13362,Q16576,Q13330,O75530,P31749,Q13555,Q9NWH9,Q93009,P31751,Q99436 21 +Dscam interactions 0.6148351648351661 0.7731435673157813 0.4394374196100037 1.0 0.7833229727421473 3 P63000,Q16539 2 +Mapk family signaling cascades 0.3231719179184109 0.7719868696645132 0.4401222043140687 1.0 0.7833229727421473 91 O00231,P49354,Q13555,P28074,P28070,Q9NWH9,P20618,Q9Y4G8,Q14168,P07196,P28072,Q99436,P60900,Q13813,P49721 15 +Separation of sister chromatids 0.3133675109532995 0.763225303504504 0.4453290407207644 1.0 0.7838254628917545 118 Q8NBT2,Q96EE3,P20618,Q16763,Q8WVM7,Q12834,P28072,Q9UL46,Q9Y6D9,P60900,O00231,O60566,Q9H3R5,P28070,P28074,Q9NXR1,P49721,Q13362,P55735,Q9UJX3,Q96EA4,Q29RF7,P49792,Q9UQE7,Q2NKX8,Q99436,Q9BS16 27 +Amyloid fiber formation 0.5053630589755571 0.762778346862159 0.4455955967184495 1.0 0.7838254628917545 7 P05067 1 +Dna damage recognition in gg ner 0.3925987127375761 0.7576467691900277 0.4486624736813254 1.0 0.7854081215815911 19 Q9H9Q2,Q9UNS2,P61201,Q9BT78,Q9H981 5 +Rnd1 gtpase cycle 0.4229941123671071 0.7482333479989411 0.4543194195062008 1.0 0.7898014593518617 15 Q9BXS4,O75976 2 +Cholesterol biosynthesis 0.3892493966411445 0.7436021677651644 0.457117191393535 1.0 0.7898014593518617 21 Q16850,Q15392 2 +Non integrin membrane ecm interactions 0.4853630564642358 0.7420950489698773 0.4580297493541954 1.0 0.7898014593518617 8 P07942,P12814 2 +Regulation of hmox1 expression and activity 0.3281963515495325 0.7393889253287433 0.4596708651668679 1.0 0.7898014593518617 50 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Plasma lipoprotein assembly remodeling and clearance 0.3888951724275025 0.7370351717914218 0.4611009608192704 1.0 0.7898014593518617 20 Q8WTV0,O15118,P61916 3 +Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants 0.6046703296703311 0.7356869070020817 0.4619212595059272 1.0 0.7898014593518617 3 P42224,P40763 2 +Signaling by kit in disease 0.6046703296703311 0.7356869070020817 0.4619212595059272 1.0 0.7898014593518617 3 P42224,P40763 2 +Interleukin 2 family signaling 0.6046703296703311 0.7356869070020817 0.4619212595059272 1.0 0.7898014593518617 3 P42224,P40763 2 +Signalling to ras 0.6046703296703309 0.7356869070020803 0.4619212595059281 1.0 0.7898014593518617 3 P11233,Q16539 2 +Parasite infection 0.3861448024009777 0.7349581916609935 0.4623649566352708 1.0 0.7898014593518617 23 P35579,Q96JJ3,Q96F07,Q9UQB8,Q14185 5 +Eph ephrin signaling 0.375362254006979 0.7322601597252306 0.4640097913314052 1.0 0.7898014593518617 28 P35579,P35580,Q7Z406,Q13464,O75116,Q92542 6 +Switching of origins to a post replicative state 0.3241331664078855 0.727780852781915 0.4667477472350276 1.0 0.7898014593518617 61 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Signaling by alk in cancer 0.3516534486581194 0.7237644510005472 0.4692103572783019 1.0 0.7898654640443578 35 P35579,P26038,Q9P2E9,P12270,Q8IWJ2,Q14203,P49792,P06753,Q9HC35,O00291,P67936,P33176 12 +Tcr signaling 0.3264810583605956 0.7227405293258942 0.4698393104828424 1.0 0.7899495812813853 51 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Beta catenin independent wnt signaling 0.3252435093559921 0.7207852327760332 0.4710416624517644 1.0 0.7901163123744476 57 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Defective intrinsic pathway for apoptosis 0.4174187491034355 0.7167875337224592 0.4735052049453436 1.0 0.7933042018644343 15 Q08379,P20700,P05067,P02545 4 +Constitutive signaling by overexpressed erbb2 0.5786010113092636 0.7126316094526576 0.4760737465289195 1.0 0.7947724038616677 4 Q96RT1 1 +Pre notch expression and processing 0.438514518443593 0.7082955952820112 0.4787617118643181 1.0 0.796434167875251 12 P15291,Q13573 2 +Formation of atp by chemiosmotic coupling 0.442505696674358 0.7072172651362827 0.4794314709024636 1.0 0.796434167875251 11 P00846,O75964 2 +Clathrin mediated endocytosis 0.3184648325899777 0.7043971676124444 0.4811854693958497 1.0 0.796434167875251 66 P11717,Q14108,P20645,Q9NZM3,P02786,Q9H9Q2,Q9UNS2,Q96RU3,Q9Y5X1,O43493,P61201,O14976,Q9BT78,O00291 14 +Mismatch repair 0.4376761767308507 0.7040209390893959 0.4814197337466055 1.0 0.796434167875251 12 Q9UQ84 1 +Costimulation by the cd28 family 0.414524597698347 0.7005400098276932 0.4835901278085863 1.0 0.796434167875251 15 P31751,P31749,Q13362 3 +Diseases of dna repair 0.431100449981964 0.6938335291653693 0.4877866129775181 1.0 0.8003228192618786 13 Q9UQ84 1 +Pten regulation 0.3116400918842991 0.6814903692648943 0.4955612586035665 1.0 0.8099662408503155 71 O00231,P28070,P28074,Q16576,P20618,P14373,Q93009,P49721,Q13330,P31751,O75530,P28072,Q99436,Q9UL46,P60900,P31749 16 +Wax and plasmalogen biosynthesis 0.5425124404783761 0.6793092612505275 0.4969419295826753 1.0 0.8099662408503155 5 O00116 1 +Sensing of dna double strand breaks 0.5659310363261801 0.6661019090999706 0.5053459643652851 1.0 0.815729661942294 4 Q92878,P52292 2 +Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.5827060693286021 0.65632326232386 0.5116161531995558 1.0 0.8229077167330754 3 Q96T60 1 +Rhoq gtpase cycle 0.3671063959518231 0.6545080827970483 0.5127845214209821 1.0 0.8238465116102209 27 P27105,P02786,Q86VI3,Q07960,Q96RU3,Q15758,Q9Y5S2,Q9Y6M7 8 +Interconversion of nucleotide di and triphosphates 0.3748593957038478 0.6448771620941212 0.5190067926601649 1.0 0.825631587014969 19 P00390 1 +Interleukin 27 signaling 0.5772000977254611 0.6368103227952654 0.5242484012986761 1.0 0.8280910882281999 3 P42224 1 +Interleukin 35 signalling 0.5772000977254611 0.6368103227952654 0.5242484012986761 1.0 0.8280910882281999 3 P42224 1 +Regulation of mrna stability by proteins that bind au rich elements 0.312017026246561 0.6354703261702075 0.5251217140327993 1.0 0.8280910882281999 66 P28070,P28074,P20618,Q13868,P49721,P28072,Q99436,P60900 8 +Signaling by scf kit 0.5308415303360118 0.6353133874051619 0.5252240440382758 1.0 0.8280910882281999 5 P42224,P63000,P40763 3 +Disinhibition of snare formation 0.517989563306775 0.6343122782257967 0.5258770451290851 1.0 0.8280910882281999 2 O00186 1 +Activation of gene expression by srebf srebp 0.3709280063606646 0.6292151010475432 0.5292082438289296 1.0 0.8294069125029739 22 Q9HCL2 1 +Cargo recognition for clathrin mediated endocytosis 0.3309375105514359 0.6224423636000329 0.533651031523104 1.0 0.8299274872141872 42 P11717,Q14108,P20645,Q9NZM3,P02786,Q9H9Q2,Q9UNS2,O43493,P61201,Q9BT78 10 +Pi 3k cascade fgfr3 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1 +Frs mediated fgfr3 signaling 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1 +Frs mediated fgfr2 signaling 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1 +Tie2 signaling 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1 +Activated ntrk2 signals through frs2 and frs3 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1 +Frs mediated fgfr1 signaling 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1 +Pi 3k cascade fgfr1 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1 +Signaling by flt3 itd and tkd mutants 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1 +Stat5 activation downstream of flt3 itd mutants 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1 +Pi 3k cascade fgfr4 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1 +Stat5 activation 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1 +Frs mediated fgfr4 signaling 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1 +Pi 3k cascade fgfr2 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8344975424212672 2 P62993 1 +Pd 1 signaling 0.5097500686624465 0.6018619839548237 0.5472660114013197 1.0 0.8344975424212672 2 P41240 1 +Signaling by leptin 0.5097500686624461 0.6018619839548227 0.5472660114013204 1.0 0.8344975424212672 2 P40763 1 +Post translational modification synthesis of gpi anchored proteins 0.4386762990311638 0.6008058149982239 0.5479693305969509 1.0 0.8344975424212672 9 Q969N2 1 +Signaling by interleukins 0.3045998168741096 0.5927633424022101 0.5533395435735982 1.0 0.8374386862461867 110 P08670,P28074,P20618,P14174,P05067,Q13126,P28072,Q99436,P49721 9 +Apc c cdc20 mediated degradation of cyclin b 0.4181505095410202 0.5880442802905045 0.5565025715443119 1.0 0.8403703735528966 11 Q9UJX3,Q12834,P06493,Q16763 4 +Cd28 dependent vav1 pathway 0.5175920835623862 0.5863171858389425 0.5576623841532706 1.0 0.8403703735528966 5 Q13177,P62993,P63000,Q16512 4 +Piwi interacting rna pirna biogenesis 0.4182398798405971 0.573745159107034 0.5661402643526967 1.0 0.8485097063520015 10 Q8N2A8 1 +P75ntr negatively regulates cell cycle via sc1 0.5020598736610726 0.5720723475786397 0.5672729620269941 1.0 0.8485097063520015 2 Q92769 1 +Death receptor signalling 0.3597785250709099 0.5676507979784131 0.5702721069253847 1.0 0.8511794477307913 24 Q8TCT8,Q92542,P78536 3 +Diseases of metabolism 0.3096032783439201 0.5631514080228013 0.5733317880167323 1.0 0.853937092299763 50 P16278,Q8NCH0,Q96L58,P15586,O43505,O14678,P15291,P08236,P10253,P54802,Q9NUN5,P10619 12 +O linked glycosylation of mucins 0.5098109287411687 0.5580676457810289 0.5767981928104919 1.0 0.8554827933368243 5 Q10472,O43505 2 +G2 m checkpoints 0.3047055517659821 0.5563497090298103 0.5779718114323367 1.0 0.8563220634155231 86 Q9UQ84,P28070,P28074,P20618,P40938,P28072,O96028,Q99436,P60900,P49721 10 +P75 ntr receptor mediated signalling 0.3784642435281019 0.5500251210710894 0.5823021434618023 1.0 0.8584816253730735 16 P78536,Q92542 2 +Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.4125060021529267 0.5471984040556763 0.5842424325075894 1.0 0.8584816253730735 10 Q16763,Q12834 2 +Pre notch processing in golgi 0.5058484383324006 0.5438433490644985 0.5865492756056521 1.0 0.8584816253730735 5 P15291 1 +Slc transporter disorders 0.3289154967833096 0.5437874864205832 0.5865877209241699 1.0 0.8584816253730735 35 P11166,O00400,Q9BTX1,Q96EE3,P55735,P12270,P57740,P53985,Q8N1F7,Q7Z3B4,P08195,P49792 12 +Regulation of cholesterol biosynthesis by srebp srebf 0.3440568735542521 0.5311745890229412 0.5952978002143423 1.0 0.863825541196713 29 Q9HCL2 1 +Diseases associated with glycosylation precursor biosynthesis 0.4480350719287994 0.5261224901969421 0.5988031033659007 1.0 0.8662357008650452 7 P10619 1 +Vitamin c ascorbate metabolism 0.5420534162258892 0.5166244383641295 0.6054183525934371 1.0 0.8708236952215923 3 P11166 1 +Alk mutants bind tkis 0.4434803762611705 0.508323177439658 0.6112267183498874 1.0 0.8755028790198734 7 Q9HC35,O00291 2 +Diseases associated with glycosaminoglycan metabolism 0.4425358529271619 0.5046550521906275 0.6138011359119777 1.0 0.8771255583164064 7 Q96L58,P15291 2 +Nephrin family interactions 0.4281115341166191 0.498167638438505 0.6183658898920914 1.0 0.879190251118019 8 Q01082,P12814,Q13813,O43707 4 +Deposition of new cenpa containing nucleosomes at the centromere 0.3951060457550945 0.4939298659202039 0.6213557113802801 1.0 0.8798896455626278 12 Q9BS16 1 +Interferon signaling 0.2972885104297937 0.4881113469463375 0.6254709742641129 1.0 0.8831504528747453 67 O15344,Q96EE3,P30511,P42224,Q9Y4X5,P19474,P10321,P12270,P57740,P55265,Q7Z3B4,P29372,Q8NFH4,Q9BTX1,P55735,P04439,Q8N1F7,P49792,Q13325,Q13555 20 +Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.5327439982021527 0.4862465473655187 0.626792372515788 1.0 0.8831504528747453 3 P11802 1 +Interleukin 20 family signaling 0.5269066376839309 0.4675520146614727 0.6401049870585744 1.0 0.8906154404916529 3 P42224 1 +Interleukin 6 signaling 0.5269066376839309 0.4675520146614727 0.6401049870585744 1.0 0.8906154404916529 3 P42224 1 +Interleukin 6 family signaling 0.5269066376839309 0.4675520146614727 0.6401049870585744 1.0 0.8906154404916529 3 P42224 1 +Apc cdc20 mediated degradation of nek2a 0.3851424281014114 0.4626518484846421 0.6436139378679973 1.0 0.8920897151714327 13 O60566,Q16763,Q12834 3 +Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.3851424281014114 0.4626518484846421 0.6436139378679973 1.0 0.8920897151714327 13 O60566,Q16763,Q12834 3 +Met promotes cell motility 0.392975455681698 0.4592099831807193 0.6460833822233272 1.0 0.8942352510340551 10 P07942,Q9NWH9 2 +Mitotic metaphase and anaphase 0.2745116726514146 0.4579106110388231 0.6470166631703851 1.0 0.8946481633042911 153 Q86XL3,Q8NBT2,Q96EE3,P20618,Q16763,Q8WVM7,P02545,Q12834,P28072,Q9UL46,Q9Y6D9,P60900,O00231,O60566,Q9H3R5,P28070,P28074,Q14739,Q9NXR1,P49721,P20700,Q13362,Q9BTX1,P55735,Q9UJX3,Q96EA4,Q8N1F7,Q29RF7,P49792,Q9UQE7,Q2NKX8,Q99436,Q9BS16 33 +Small interfering rna sirna biogenesis 0.5035807128189961 0.4512066000849135 0.6518406532154877 1.0 0.8985019724445508 4 O75569 1 +Pyruvate metabolism and citric acid tca cycle 0.3152504405670104 0.4499306141522501 0.652760472294736 1.0 0.8985019724445508 37 O95563,P21796,P53985,P48735 4 +Stat3 nuclear events downstream of alk signaling 0.5023358065402752 0.4472124559834572 0.6547216686993402 1.0 0.899125566469172 4 Q96ST3,Q92769,P40763 3 +Regulation of insulin secretion 0.3806560031868828 0.4412644506796819 0.6590215588788855 1.0 0.899803920708942 13 P46940,P11166,Q9UBI6,O43865 4 +Pre notch processing in the endoplasmic reticulum 0.4663553968689855 0.4411266967927643 0.6591212773118722 1.0 0.899803920708942 2 Q9H488 1 +Opioid signalling 0.341256955734167 0.440346852025481 0.6596859120598559 1.0 0.899803920708942 19 O43865 1 +Neddylation 0.2932037033959241 0.4382020209789456 0.6612398436986138 1.0 0.9010511990051708 81 O00231,P60900,O60826,Q16576,P28074,Q9UNS2,P28070,P20618,Q9H9Q2,Q9UBW8,Q7Z4G1,P61201,Q92564,Q9BT78,P28072,Q99436,Q9UL46,P49721 18 +Interleukin 4 and interleukin 13 signaling 0.3791906079242515 0.4343353024513988 0.6640449717582761 1.0 0.903126800393254 13 P08670,P09601,Q07820,P31749 4 +Met activates ptk2 signaling 0.4726407822311689 0.4295396974142842 0.6675305109398249 1.0 0.9052458998211868 5 P07942 1 +Sensory processing of sound 0.338074633914437 0.4218250501645936 0.6731527198844374 1.0 0.91024201757886 19 P35579,Q01082,Q13813,O14936 4 +Syndecan interactions 0.4451661652226334 0.4192605323147208 0.6750257374287023 1.0 0.9118995820105864 6 P17301,P12814,O14936 3 +Gab1 signalosome 0.5098901098901115 0.4147338279729401 0.6783367656242727 1.0 0.9128715403673356 3 P62993,P41240 2 +Signal regulatory protein family interactions 0.5098901098901114 0.4147338279729401 0.6783367656242727 1.0 0.9128715403673356 3 P62993,Q08722 2 +Deactivation of the beta catenin transactivating complex 0.3813027623845995 0.408704066553077 0.6827568491268452 1.0 0.9170680652237606 10 P31751,P31749 2 +Listeria monocytogenes entry into host cells 0.4026300560270959 0.3987521878581186 0.6900758098478708 1.0 0.9198834589173605 8 P42566,Q9NWH9 2 +Negative regulation of the pi3k akt network 0.3492492635705874 0.3925557626868922 0.6946476180950965 1.0 0.9215547517862458 16 Q13362,P84095,Q9NWH9,P31751,P31749 5 +Mecp2 regulates transcription of neuronal ligands 0.5021978021978037 0.3917352133537207 0.6952538688067986 1.0 0.9215547517862458 3 P51608,Q96ST3 2 +Adherens junctions interactions 0.4115594131781473 0.3892816864050446 0.6970677821334641 1.0 0.9222296333295056 7 P35222,P35221,Q9BY67 3 +Rho gtpases activate iqgaps 0.3712779299995678 0.3845634386649921 0.7005608863915573 1.0 0.92310583730407 12 Q86VI3,P35222,P35221 3 +Activated notch1 transmits signal to the nucleus 0.4820730995965838 0.3842103170304916 0.7008225721996104 1.0 0.92310583730407 4 P78536 1 +Mitotic spindle checkpoint 0.2869405704430443 0.3821886966672906 0.7023214053728648 1.0 0.92310583730407 67 Q8NBT2,Q96EE3,Q6P1K2,Q16763,Q12834,Q9Y6D9,O60566,Q9H3R5,P57740,Q9NXR1,Q8NFH4,Q13362,P55735,Q9UJX3,Q96EA4,P49792,Q15691,Q96IY1,Q2NKX8,Q9BS16,Q14738 21 +Reproduction 0.3255317726194815 0.3784086872027071 0.7051270157092906 1.0 0.92310583730407 27 P20700,Q9UQE7,P11802,Q9UH99,Q92878,Q8N3U4,Q8WVM7,P02545,P15291,Q9BTC0,Q14683 11 +Pkmts methylate histone lysines 0.3534469925487228 0.3762807350245141 0.7067081999229474 1.0 0.92310583730407 15 O75530 1 +Polymerase switching 0.3596743602506363 0.3733180827108707 0.7089117196405985 1.0 0.924867234234818 14 P41440 1 +Programmed cell death 0.2877068461951152 0.3669192577801668 0.7136792461976924 1.0 0.9270231033240206 106 P20700,O00231,P60900,P49354,P08670,P28070,P28074,Q13464,P20618,P02545,O75955,P28072,Q99436,P41440,Q13813,P49721 16 +Met activates rap1 and rac1 0.4278767477718062 0.361534351242581 0.717700030450036 1.0 0.928735611632204 6 Q9NWH9 1 +Cohesin loading onto chromatin 0.3697631021498927 0.3605604122886637 0.7184280876620739 1.0 0.928735611632204 10 Q9UQE7,Q8WVM7,Q8N3U4,Q29RF7,Q9NTI5 5 +Apoptotic execution phase 0.3152048365635996 0.3537954869470252 0.7234921559287042 1.0 0.9326628066821082 30 P20700,P49354,P08670,P02545,Q13813 5 +Phenylalanine metabolism 0.4383411150782698 0.3486446653965739 0.7273560910807881 1.0 0.9359312624044114 2 P09417 1 +Metabolism of water soluble vitamins and cofactors 0.2932292822036218 0.3442706635300925 0.7306427444636827 1.0 0.936738514057624 45 P11166,Q9NVS9,Q9NPF0,Q9H2D1,Q96EN8,P43490,Q9NUN5,O14678,Q8NFF5,Q9NRN7,P78417,O00764,Q9HC21,P41440,Q99707,Q9NVE7 16 +Tcf dependent signaling in response to wnt 0.282015069174541 0.3389731059742884 0.7346299903329179 1.0 0.9390658827208512 68 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Polymerase switching on the c strand of the telomere 0.3372231831126751 0.3316555337043869 0.7401493808266801 1.0 0.9412188425855528 16 P41440 1 +Neuronal system 0.2843939681168571 0.3282750090476694 0.7427037380198636 1.0 0.9427653755585476 58 Q14012,P54619,Q13555,P80404,Q13136,Q14168,Q9UBI6,O75955,P10586,P41440,P07196 11 +Rnd3 gtpase cycle 0.3203479053490922 0.3241720031598482 0.7458078167964566 1.0 0.9439970311709984 18 Q86UP2,Q07065,O75976 3 +Nuclear receptor transcription pathway 0.4295523207909837 0.3218150182862841 0.7475928361229027 1.0 0.9439970311709984 2 Q15648 1 +Dna replication pre initiation 0.2791156337255669 0.3102212752769938 0.7563926927445142 1.0 0.949872820032995 68 P28070,P28074,P20618,P49721,P28072,Q99436,P60900 7 +Vegfr2 mediated vascular permeability 0.353931840153442 0.3028390873650514 0.7620124938550514 1.0 0.9514108698395848 11 P31749,P31751,P35221 3 +Signaling by wnt in cancer 0.355206252760706 0.3026968836641108 0.762120872922257 1.0 0.9514108698395848 10 P48729,P35222,Q13362 3 +Ikba variant leads to eda id 0.4218621257896104 0.2992683328564875 0.7647353146950711 1.0 0.9518657759764622 2 O15111 1 +Signaling by rho gtpases miro gtpases and rhobtb3 0.3099201057668907 0.2924709275157063 0.7699265850838894 1.0 0.9532746558727594 282 P78371,Q8NBT2,P84095,Q86VI3,P30519,Q96N67,P06753,Q13505,Q12834,Q9Y5S2,Q9UQB8,Q92888,P35579,Q9H3R5,Q96JJ3,Q86UP2,Q7Z406,Q07960,Q07065,P02786,O75116,Q9BXS4,P67936,Q13813,P33176,P20700,P12814,Q9NZM3,O15173,P55735,Q96RU3,Q13464,O75976,Q96F07,Q96EA4,Q7L576,P41440,P11274,Q14185,Q8NBN3,Q9Y6M7,P35580,P08670,Q01082,O43663,Q9BT78,O75955,Q96HY6,Q9BS16 49 +Keratan sulfate degradation 0.4268516516183419 0.2897977017859582 0.7719710061699891 1.0 0.9536687208582376 5 P16278,P15586 2 +Translesion synthesis by polk 0.3509106113295766 0.2862909664003602 0.774655276473877 1.0 0.9540990249577732 10 P41440 1 +Esr mediated signaling 0.2811694204792111 0.270386611930112 0.7868628387866026 1.0 0.9607363430245434 47 Q9UQE7,Q9HCL2,Q9HCE1,Q8WVM7,P31751,Q9UBI6,P31749 7 +Platelet homeostasis 0.3435795331076976 0.2681263418047017 0.7886020701238385 1.0 0.9618105391624924 12 Q9UBI6,P16615,Q13362 3 +Regulation of tp53 expression and degradation 0.3403439201006695 0.2627292063320163 0.7927593039702285 1.0 0.9618105391624924 13 Q93009,P31751,P31749,Q13362 4 +Grb2 sos provides linkage to mapk signaling for integrins 0.4081296347157281 0.2612675346474137 0.7938862008843 1.0 0.9618105391624924 2 P62993 1 +Apoptosis 0.2788557949159255 0.2581729558102715 0.7962734287186044 1.0 0.9638510676348392 92 P20700,O00231,P49354,P08670,P28070,P28074,Q13464,P20618,P02545,P28072,Q99436,P60900,Q13813,P49721 14 +Dna double strand break repair 0.2762133587517754 0.2560324576059755 0.7979257748501101 1.0 0.96421733856244 56 O96028,Q9UQ84,P12956 3 +Diseases of programmed cell death 0.3007966063757459 0.2506238615090529 0.8021049315769013 1.0 0.9676077470820668 29 P20700,Q08379,P02545,O75530,P05067 5 +Neurotransmitter release cycle 0.3581140970496762 0.2453106188184973 0.806215930279679 1.0 0.9690232433745896 8 P80404,Q13136 2 +Linoleic acid la metabolism 0.4015380390002708 0.2440962186134425 0.8071563010965563 1.0 0.9690232433745896 2 P33121 1 +Eph ephrin mediated repulsion of cells 0.3385697801678712 0.2437754350812522 0.8074047464313472 1.0 0.9690232433745896 11 Q92542 1 +Bbsome mediated cargo targeting to cilium 0.3468234453564495 0.2371655510169016 0.8125283602675131 1.0 0.9711407665569102 9 P78371 1 +Diseases of immune system 0.4390450754412024 0.2273002879332384 0.8201902492283719 1.0 0.9711407665569102 3 O15111 1 +Cytokine signaling in immune system 0.2714628985987332 0.2231021151311809 0.8234560322053235 1.0 0.9725106791489349 181 O15344,P30511,P20618,P14174,Q13126,P28072,P60900,P05067,O00231,P19474,P28070,P28074,P49721,P20700,P55735,P78536,P08670,Q13555,Q99436 19 +Inlb mediated entry of listeria monocytogenes into host cell 0.3752892981578248 0.2092102425961602 0.8342841169121398 1.0 0.9761511443523126 6 Q9NWH9 1 +Synthesis of substrates in n glycan biosythesis 0.3102117493699463 0.2058386398492171 0.8369169572007933 1.0 0.9761511443523126 16 P10619 1 +S phase 0.2742324948059929 0.2042730869185779 0.8381401000692013 1.0 0.9761511443523126 101 Q9UQE7,O00231,P60900,Q29RF7,P28070,P28074,P20618,Q16763,O75419,Q8WVM7,P31751,P40938,Q14566,Q9BRT9,P28072,Q99436,P41440,P49721 18 +Energy dependent regulation of mtor by lkb1 ampk 0.3517752960088014 0.2014727804657463 0.8403289110802903 1.0 0.9761511443523126 7 Q15382,P54619 2 +Mitotic telophase cytokinesis 0.3245177534734972 0.2008564813309674 0.8408107970370771 1.0 0.9761511443523126 13 Q9UQE7,Q02241,Q8WVM7,Q8N3U4,Q29RF7,Q14683,Q9NTI5 7 +Signaling by braf and raf1 fusions 0.2976000824736072 0.1999649375592678 0.8415080030404987 1.0 0.9761511443523126 24 Q9NRY5,Q96PU8,Q13555,Q6WCQ1,P02545 5 +Hdr through homologous recombination hrr 0.2955348228178907 0.195746711353542 0.8448084212171374 1.0 0.9761511443523126 26 Q9UQ84,P41440 2 +Adenylate cyclase inhibitory pathway 0.4239010989011006 0.1951605695459501 0.8452672464235349 1.0 0.9761511443523126 3 P63096,P04899 2 +Regulation of gene expression in beta cells 0.408655524971702 0.1942083240657538 0.8460127652989298 1.0 0.9761511443523126 4 P31751 1 +Phosphorylation of emi1 0.4222296108088759 0.1918001580211615 0.8478987471791652 1.0 0.9761511443523126 3 Q12834 1 +Cell cell communication 0.289710481383548 0.1870693876584185 0.8516062295438562 1.0 0.9779243499814942 29 P12814,P35221,Q9BY67,O43707,Q01082,Q8N3R9,Q13813,P35222,O14936 9 +Cell cycle checkpoints 0.2565033882476371 0.181355890044553 0.8560882393495055 1.0 0.981471382622826 154 Q8NBT2,Q96EE3,Q92878,P20618,Q16763,O75419,P40938,Q12834,P28072,Q9UL46,Q9Y6D9,Q9Y619,P60900,Q9UQ84,O00231,O60566,Q9H3R5,P28070,P28074,Q9NXR1,P49721,Q13362,P55735,Q9UJX3,Q96EA4,O96028,P49792,Q2NKX8,Q99436,Q14566,Q9BS16 31 +Ncam signaling for neurite out growth 0.3605584428137088 0.1738167749509753 0.8620094605682826 1.0 0.9841847260227016 6 Q13813 1 +Tp53 regulates transcription of death receptors and ligands 0.3707772589947731 0.1735994149705959 0.8621802918254611 1.0 0.9841847260227016 2 P04637 1 +Type i hemidesmosome assembly 0.3696786597088676 0.1713822620664341 0.863923201252135 1.0 0.9841847260227016 2 Q15149 1 +Assembly of collagen fibrils and other multimeric structures 0.3696786597088676 0.1713822620664341 0.863923201252135 1.0 0.9841847260227016 2 Q15149 1 +Condensation of prometaphase chromosomes 0.3244242808238441 0.16830107277467 0.8663464299493218 1.0 0.9848478520417562 9 P06493,O95347,Q9NTJ3,Q15021,Q15003,P67870 6 +Ca2 pathway 0.3577013083994919 0.1673542469518957 0.8670913230360631 1.0 0.9848478520417562 6 Q9HCE1,Q9UBI6 2 +Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.40824175824176 0.1651588727011975 0.8688189354775748 1.0 0.9848478520417562 3 P63000,O14786 2 +Homologous dna pairing and strand exchange 0.2985528292593037 0.157078667033664 0.8751828501000409 1.0 0.9877957181119394 16 Q9UQ84 1 +Hdr through single strand annealing ssa 0.2985528292593037 0.157078667033664 0.8751828501000409 1.0 0.9877957181119394 16 Q9UQ84 1 +Signaling by erbb2 in cancer 0.3713449565403116 0.1565165553531337 0.8756258707748845 1.0 0.9877957181119394 5 Q96RT1 1 +Signaling by erbb2 ecd mutants 0.3713449565403116 0.1565165553531337 0.8756258707748845 1.0 0.9877957181119394 5 Q96RT1 1 +Glucagon like peptide 1 glp1 regulates insulin secretion 0.3701071880895624 0.1540576100321204 0.8775643114791303 1.0 0.9883997720816105 5 P46940,Q9UBI6 2 +Signaling by erbb2 0.3106619034908053 0.1490928692870219 0.8814803524886972 1.0 0.9906613141197892 12 Q96RT1,P31751,Q16543,P31749 4 +Intraflagellar transport 0.3056996864341485 0.1477106267971159 0.8825711446688702 1.0 0.9908416769628876 14 Q9Y366,A0AVF1 2 +Unwinding of dna 0.3094106356498832 0.1460734194144907 0.8838634295532231 1.0 0.9908416769628876 10 Q14566,Q9BRT9 2 +Platelet sensitization by ldl 0.3278939409882084 0.1426037178561819 0.8866031610699394 1.0 0.991447503132972 7 Q14738,Q13362 2 +E2f enabled inhibition of pre replication complex formation 0.3628637351292202 0.1401359049316304 0.8885526124503871 1.0 0.9920599930545916 5 Q9Y619 1 +Tp53 regulates metabolic genes 0.269139125753199 0.1373941773762004 0.8907192331842564 1.0 0.9920599930545916 40 P20674,P54619,Q7LG56,P31751,P00390,P31749,P00403 7 +Synthesis of dna 0.2659784528666107 0.1329076530802033 0.8942664143211674 1.0 0.9921428171484448 88 O00231,P60900,P28070,P28074,P20618,P40938,Q9BRT9,P28072,Q99436,P41440,P49721 11 +Regulated necrosis 0.2816163466674679 0.1315120387504301 0.8953702637416256 1.0 0.9924183808938744 19 P41440 1 +Processing of dna double strand break ends 0.2805484471413052 0.130812697708152 0.8959234779964573 1.0 0.9924183808938744 28 O96028,Q9UQ84 2 +Integrin cell surface interactions 0.3211231797742668 0.1277917496213718 0.8983137793780409 1.0 0.9928424105727596 7 Q9BX67,P17301,P35613 3 +Translesion synthesis by polh 0.3033681105859644 0.1270390935778116 0.8989094570019749 1.0 0.9928424105727596 13 P41440 1 +Mitotic g1 phase and g1 s transition 0.2615422007862957 0.1125599809348174 0.9103794139364472 1.0 0.9995749705444285 81 O00231,P28070,P28074,P20618,O75419,P31350,P31751,Q14566,P28072,Q99436,P60900,P49721 12 +Negative regulation of met activity 0.3076110447635577 0.1119108285445725 0.910894110604926 1.0 0.9995749705444285 8 Q9NWH9 1 +Transcriptional activation of mitochondrial biogenesis 0.2982824346418836 0.1109318577570206 0.9116703826661344 1.0 0.9995749705444285 13 O00411,Q96RR1 2 +Sars cov infections 0.2568191784457093 0.1071183381008263 0.914695099170704 1.0 0.9995749705444285 69 Q99720,P49354,Q13464,O75116,Q14457 5 +Homology directed repair 0.2622467376295883 0.1052077170179513 0.9162109874138132 1.0 0.9995749705444285 43 O96028,Q9UQ84 2 +Signaling by hippo 0.30770878584314 0.1009542108688868 0.9195868088325344 1.0 0.9995749705444285 7 Q13043,Q4VCS5 2 +Signaling by receptor tyrosine kinases 0.2593482819881195 0.1009290467794472 0.919606784841406 1.0 0.9995749705444285 124 P07942,Q9Y487,Q96JJ3,Q13464,Q9NWH9,O75116,Q96F07,Q93050,P31751,Q8WX92,O43865,P78536,Q7L576,Q9UQB8,Q92542,Q14185 16 +Rhof gtpase cycle 0.2780024432173055 0.0975064255796248 0.9223242316731556 1.0 0.9995749705444285 17 P20700,P12814,Q8TAA9,Q9UEY8,Q07960,P42166,Q02952,Q9Y6M7 8 +Signaling by type 1 insulin like growth factor 1 receptor igf1r 0.3362144257601666 0.0958158054360232 0.923666864193645 1.0 0.9995749705444285 5 P31751 1 +Inositol phosphate metabolism 0.3178443772339894 0.0912672010678067 0.9272802789461084 1.0 1.0 6 Q96PE3,Q9NPH2,Q9BW91,P19174,Q01968 5 +Adaptive immune system 0.2722811688349957 0.0897969721357841 0.9284485543567712 1.0 1.0 206 Q9Y496,P30511,P20618,Q16763,Q5KU26,Q12834,P28072,Q9UL46,P60900,P55786,O00231,P19474,P10321,Q9UIQ6,P28070,P28074,Q14203,O75935,O43865,P10619,P49721,O94874,Q13049,P33176,Q13362,P55735,Q9UJX3,P52732,P04439,O95239,P31749,P52888,Q9NZ08,P31751,Q99538,Q99436 36 +Translocation of slc2a4 glut4 to the plasma membrane 0.2608013095693706 0.0865198007608968 0.931053216359647 1.0 1.0 40 P35579,Q9UIQ6,P54619,P31751 4 +Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.2904599380962877 0.0835544300076131 0.9334106997640574 1.0 1.0 9 Q93009,Q16763 2 +Dap12 interactions 0.3262781748213254 0.08203614217945 0.9346179730009618 1.0 1.0 5 P62993,P01889,P10321,P63000 4 +Akt phosphorylates targets in the cytosol 0.3059935382417012 0.07371471312729 0.9412373912589028 1.0 1.0 6 P31751 1 +Cell junction organization 0.2669056744214946 0.0713863234358335 0.943090294156086 1.0 1.0 19 Q8N3R9,Q9BY67 2 +Transcriptional regulation by e2f6 0.2829610529756042 0.0685757798341913 0.945327298363242 1.0 1.0 12 P31350,O75530 2 +Constitutive signaling by egfrviii 0.3261885133278484 0.0670429580386523 0.9465475045404904 1.0 1.0 4 P62993,P07900,Q16543 3 +Constitutive signaling by ligand responsive egfr cancer variants 0.3261885133278484 0.0670429580386523 0.9465475045404904 1.0 1.0 4 P62993,P07900,Q16543 3 +Signaling by egfr in cancer 0.3261885133278484 0.0670429580386523 0.9465475045404904 1.0 1.0 4 P62993,P07900,Q16543 3 +Meiosis 0.2686466778487039 0.0668290375378563 0.9467178064645988 1.0 1.0 26 P20700,Q9UQE7,P11802,Q9UH99,Q92878,Q8N3U4,Q8WVM7,P02545,Q9BTC0,Q14683 10 +Signal amplification 0.2836313617606746 0.0660113543996318 0.9473687856694974 1.0 1.0 8 Q16539,Q14344,P08754,Q13685,P04899,Q9UBI6,P63096 7 +Synthesis of pips at the early endosome membrane 0.3234349453993151 0.0643806643470927 0.9486671256982284 1.0 1.0 4 Q96PE3 1 +Pecam1 interactions 0.326098901098903 0.0611831800045689 0.9512133250468822 1.0 1.0 3 Q06124,P06756 2 +Constitutive signaling by akt1 e17k in cancer 0.2831489140842055 0.0604369487170864 0.9518076316073332 1.0 1.0 7 O15111,P31751,P31749 3 +Pp2a mediated dephosphorylation of key metabolic factors 0.3233516483516502 0.059129294061128 0.9528491261681332 1.0 1.0 3 P30153,Q14738 2 +G1 s specific transcription 0.2766838147121669 0.0571543789413046 0.9544222190484488 1.0 1.0 11 P31350,Q9Y619,O75419 3 +Neurexins and neuroligins 0.2734213819597552 0.0553117757352158 0.9558900808491002 1.0 1.0 10 Q14168 1 +Extra nuclear estrogen signaling 0.2774304120887577 0.0548396427955911 0.9562662175219244 1.0 1.0 12 P31751,Q9UBI6 2 +Defects in vitamin and cofactor metabolism 0.2775603692615556 0.0523179098960324 0.9582753828260931 1.0 1.0 13 Q9NUN5 1 +Response of eif2ak1 hri to heme deficiency 0.3042044517724773 0.0483005608907998 0.9614767075510012 1.0 1.0 4 P05198,P41091,P08243 3 +Kinesins 0.2619438896753199 0.0460179450121506 0.963295947009254 1.0 1.0 21 Q9Y496,Q07866,O95235,Q02241,P52732,Q14807,O95239,P33176 8 +M phase 0.2734802797700281 0.0437462827081837 0.9651066462412412 1.0 1.0 218 Q86XL3,Q01105,Q8NBT2,Q96EE3,Q8N3U4,Q16763,P20618,Q9H6D7,P02545,Q8WVM7,Q9NTJ3,P28072,Q12834,Q9UL46,Q9Y6D9,P60900,O00231,O60566,Q96CW5,Q9H3R5,Q08379,P28070,P28074,P12270,Q14203,Q14739,O75935,Q9NXR1,Q15021,O43805,P49721,P20700,O15078,Q13362,Q9BTX1,P55735,Q9UJX3,Q96EA4,Q8N1F7,Q29RF7,P49792,Q9UQE7,O94927,Q96CS2,O95684,Q9BSJ2,Q2NKX8,Q99436,Q9UPN4,Q9BS16 50 +Nuclear envelope breakdown 0.2520319799121704 0.0386081904423536 0.9692027721343192 1.0 1.0 41 P20700,P06493,Q8NFH4,Q96EE3,Q9BTX1,P12270,P55735,P57740,Q9Y2U8,P02545,P42166,Q8N1F7,Q7Z3B4,P49792 14 +Cdc6 association with the orc origin complex 0.2767243748282619 0.0321304390137074 0.9743680291137532 1.0 1.0 4 O43913,Q9Y619,Q9UBD5 3 +Zbp1 dai mediated induction of type i ifns 0.271852666300172 0.0306242961265443 0.975569165727712 1.0 1.0 5 O15111,O14920,Q9NZI8,Q08211 4 +Rip mediated nfkb activation via zbp1 0.2718526663001722 0.0306242961265443 0.975569165727712 1.0 1.0 5 O15111,O14920,Q9NZI8,Q08211 4 +Rho gtpase effectors 0.250653715264051 0.027358154599011 0.9781740735375362 1.0 1.0 129 Q8NBT2,P84095,Q86VI3,Q12834,Q9UQB8,Q9Y6D9,P35579,O60566,P35221,Q9H3R5,Q86UP2,Q7Z406,O75116,Q9NXR1,Q9Y6W5,P33176,Q13362,P55735,Q13464,Q96F07,Q96EA4,Q7L576,P49792,P35580,O43663,Q2NKX8,Q9BS16 27 +Platelet aggregation plug formation 0.2452570800110045 0.0165648657077538 0.9867837538142594 1.0 1.0 6 P62993,P31749,Q9Y490,P18031,P41240 5 +Integrin signaling 0.2452570800110045 0.0165648657077538 0.9867837538142594 1.0 1.0 6 P62993,P31749,Q9Y490,P18031,P41240 5 +Processing of intronless pre mrnas 0.2531782646540392 0.0059936373920085 0.9952177978942732 1.0 1.0 16 Q5KU26,Q92797 2 +Metabolism of vitamins and cofactors 0.2437824577408127 0.005065355670708 0.995958448198281 1.0 1.0 57 Q96EN8,Q9Y5Z9,Q9HC21,Q99707,Q9NVE7,P11166,Q9NVS9,O14678,Q9NRN7,P78417,Q9H2D1,P43490,Q9BQG2,Q8N0U8,Q9NPF0,P41440,P31749,Q9NUN5,O00764,Q8NFF5 20 +Mtor signalling 0.2508499987912997 3.137203293250283e-05 0.9999749687392864 1.0 1.0 16 P31751,P54619,P31749 3 diff --git a/msigdb_reactome/selections.json b/msigdb_reactome/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..70d024d29ed72cf916c8948b9ea9681a925d851a --- /dev/null +++ b/msigdb_reactome/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["2 ltr circle formation", "A tetrasaccharide linker sequence is required for gag synthesis", "Abacavir metabolism", "Abacavir transmembrane transport", "Abacavir transport and metabolism", "Abc family proteins mediated transport", "Abc transporter disorders", "Abc transporters in lipid homeostasis", "Aberrant regulation of mitotic exit in cancer due to rb1 defects", "Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects", "Abortive elongation of hiv 1 transcript in the absence of tat", "Acetylcholine neurotransmitter release cycle", "Acetylcholine regulates insulin secretion", "Activated notch1 transmits signal to the nucleus", "Activated ntrk2 signals through cdk5", "Activated ntrk2 signals through frs2 and frs3", "Activated ntrk2 signals through fyn", "Activated ntrk2 signals through pi3k", "Activated ntrk2 signals through ras", "Activated ntrk3 signals through ras", "Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3", "Activated tak1 mediates p38 mapk activation", "Activation of ampk downstream of nmdars", "Activation of anterior hox genes in hindbrain development during early embryogenesis", "Activation of atr in response to replication stress", "Activation of bad and translocation to mitochondria", "Activation of bh3 only proteins", "Activation of gene expression by srebf srebp", "Activation of irf3 irf7 mediated by tbk1 ikk epsilon", "Activation of kainate receptors upon glutamate binding", "Activation of nima kinases nek9 nek6 nek7", "Activation of nmda receptors and postsynaptic events", "Activation of noxa and translocation to mitochondria", "Activation of ppargc1a pgc 1alpha by phosphorylation", "Activation of puma and translocation to mitochondria", "Activation of rac1", "Activation of rac1 downstream of nmdars", "Activation of smo", "Activation of the ap 1 family of transcription factors", "Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s", "Activation of the pre replicative complex", "Acyl chain remodeling of cl", "Acyl chain remodelling of pc", "Acyl chain remodelling of pg", "Acyl chain remodelling of pi", "Acyl chain remodelling of ps", "Adaptive immune system", "Adenylate cyclase inhibitory pathway", "Adherens junctions interactions", "Adora2b mediated anti inflammatory cytokines production", "Adp signalling through p2y purinoceptor 1", "Adp signalling through p2y purinoceptor 12", "Adrenaline noradrenaline inhibits insulin secretion", "Advanced glycosylation endproduct receptor signaling", "Aflatoxin activation and detoxification", "Aggrephagy", "Akt phosphorylates targets in the cytosol", "Akt phosphorylates targets in the nucleus", "Alk mutants bind tkis", "Alpha linolenic omega3 and linoleic omega6 acid metabolism", "Alpha oxidation of phytanate", "Alpha protein kinase 1 signaling pathway", "Amino acid transport across the plasma membrane", "Amino acids regulate mtorc1", "Ampk inhibits chrebp transcriptional activation activity", "Amyloid fiber formation", "Anchoring of the basal body to the plasma membrane", "Androgen biosynthesis", "Anti inflammatory response favouring leishmania parasite infection", "Antigen activates b cell receptor bcr leading to generation of second messengers", "Antigen presentation folding assembly and peptide loading of class i mhc", "Antigen processing cross presentation", "Antigen processing ubiquitination proteasome degradation", "Antimicrobial peptides", "Antiviral mechanism by ifn stimulated genes", "Apc c cdc20 mediated degradation of cyclin b", "Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1", "Apc c mediated degradation of cell cycle proteins", "Apc cdc20 mediated degradation of nek2a", "Apex1 independent resolution of ap sites via the single nucleotide replacement pathway", "Apobec3g mediated resistance to hiv 1 infection", "Apoptosis", "Apoptosis induced dna fragmentation", "Apoptotic cleavage of cell adhesion proteins", "Apoptotic cleavage of cellular proteins", "Apoptotic execution phase", "Apoptotic factor mediated response", "Aquaporin mediated transport", "Arachidonate production from dag", "Arachidonic acid metabolism", "Arms mediated activation", "Aryl hydrocarbon receptor signalling", "Asparagine n linked glycosylation", "Aspartate and asparagine metabolism", "Assembly and cell surface presentation of nmda receptors", "Assembly of active lpl and lipc lipase complexes", "Assembly of collagen fibrils and other multimeric structures", "Assembly of the hiv virion", "Assembly of the orc complex at the origin of replication", "Association of tric cct with target proteins during biosynthesis", "Asymmetric localization of pcp proteins", "Atf4 activates genes in response to endoplasmic reticulum stress", "Atf6 atf6 alpha activates chaperone genes", "Atf6 atf6 alpha activates chaperones", "Attachment and entry", "Attachment of gpi anchor to upar", "Attenuation phase", "Auf1 hnrnp d0 binds and destabilizes mrna", "Aurka activation by tpx2", "Autophagy", "B wich complex positively regulates rrna expression", "Base excision repair", "Base excision repair ap site formation", "Basigin interactions", "Bbsome mediated cargo targeting to cilium", "Beta catenin independent wnt signaling", "Beta catenin phosphorylation cascade", "Beta oxidation of butanoyl coa to acetyl coa", "Beta oxidation of decanoyl coa to octanoyl coa coa", "Beta oxidation of hexanoyl coa to butanoyl coa", "Beta oxidation of lauroyl coa to decanoyl coa coa", "Beta oxidation of octanoyl coa to hexanoyl coa", "Beta oxidation of pristanoyl coa", "Beta oxidation of very long chain fatty acids", "Bh3 only proteins associate with and inactivate anti apoptotic bcl 2 members", "Bicarbonate transporters", "Bile acid and bile salt metabolism", "Binding and uptake of ligands by scavenger receptors", "Binding of tcf lef ctnnb1 to target gene promoters", "Biological oxidations", "Biosynthesis of epa derived spms", "Biosynthesis of maresins", "Biosynthesis of specialized proresolving mediators spms", "Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein", "Biotin transport and metabolism", "Bmal1 clock npas2 activates circadian gene expression", "Branched chain amino acid catabolism", "Budding and maturation of hiv virion", "Butyrate response factor 1 brf1 binds and destabilizes mrna", "C type lectin receptors clrs", "Ca dependent events", "Ca2 pathway", "Calcineurin activates nfat", "Calnexin calreticulin cycle", "Camk iv mediated phosphorylation of creb", "Carboxyterminal post translational modifications of tubulin", "Cardiac conduction", "Cargo concentration in the er", "Cargo recognition for clathrin mediated endocytosis", "Cargo trafficking to the periciliary membrane", "Carnitine metabolism", "Caspase activation via death receptors in the presence of ligand", "Caspase activation via extrinsic apoptotic signalling pathway", "Caspase mediated cleavage of cytoskeletal proteins", "Cation coupled chloride cotransporters", "Cd163 mediating an anti inflammatory response", "Cd209 dc sign signaling", "Cd28 co stimulation", "Cd28 dependent pi3k akt signaling", "Cd28 dependent vav1 pathway", "Cdc42 gtpase cycle", "Cdc6 association with the orc origin complex", "Cdt1 association with the cdc6 orc origin complex", "Cell cell communication", "Cell cell junction organization", "Cell cycle", "Cell cycle checkpoints", "Cell cycle mitotic", "Cell death signalling via nrage nrif and nade", "Cell extracellular matrix interactions", "Cell junction organization", "Cell surface interactions at the vascular wall", "Cellular hexose transport", "Cellular response to chemical stress", "Cellular response to heat stress", "Cellular response to hypoxia", "Cellular response to starvation", "Cellular responses to stimuli", "Cellular senescence", "Chaperone mediated autophagy", "Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex", "Chl1 interactions", "Cholesterol biosynthesis", "Choline catabolism", "Chondroitin sulfate biosynthesis", "Chondroitin sulfate dermatan sulfate metabolism", "Chrebp activates metabolic gene expression", "Chromatin modifying enzymes", "Chromosome maintenance", "Chylomicron assembly", "Chylomicron clearance", "Cilium assembly", "Circadian clock", "Citric acid cycle tca cycle", "Class a 1 rhodopsin like receptors", "Class b 2 secretin family receptors", "Class i mhc mediated antigen processing presentation", "Class i peroxisomal membrane protein import", "Clathrin mediated endocytosis", "Clec7a dectin 1 induces nfat activation", "Clec7a dectin 1 signaling", "Cobalamin cbl vitamin b12 transport and metabolism", "Coenzyme a biosynthesis", "Cohesin loading onto chromatin", "Collagen biosynthesis and modifying enzymes", "Collagen degradation", "Collagen formation", "Common pathway of fibrin clot formation", "Competing endogenous rnas cernas regulate pten translation", "Complement cascade", "Complex i biogenesis", "Condensation of prometaphase chromosomes", "Condensation of prophase chromosomes", "Constitutive signaling by aberrant pi3k in cancer", "Constitutive signaling by akt1 e17k in cancer", "Constitutive signaling by egfrviii", "Constitutive signaling by ligand responsive egfr cancer variants", "Constitutive signaling by overexpressed erbb2", "Conversion from apc c cdc20 to apc c cdh1 in late anaphase", "Cooperation of pdcl phlp1 and tric cct in g protein beta folding", "Cooperation of prefoldin and tric cct in actin and tubulin folding", "Copi dependent golgi to er retrograde traffic", "Copi independent golgi to er retrograde traffic", "Copi mediated anterograde transport", "Copii mediated vesicle transport", "Costimulation by the cd28 family", "Creatine metabolism", "Creb phosphorylation", "Creb1 phosphorylation through nmda receptor mediated activation of ras signaling", "Creb1 phosphorylation through the activation of adenylate cyclase", "Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde", "Cristae formation", "Crmps in sema3a signaling", "Cross presentation of particulate exogenous antigens phagosomes", "Cross presentation of soluble exogenous antigens endosomes", "Cs ds degradation", "Ctla4 inhibitory signaling", "Cyclin a b1 b2 associated events during g2 m transition", "Cyclin a cdk2 associated events at s phase entry", "Cyclin d associated events in g1", "Cytochrome c mediated apoptotic response", "Cytochrome p450 arranged by substrate type", "Cytokine signaling in immune system", "Cytoprotection by hmox1", "Cytosolic iron sulfur cluster assembly", "Cytosolic sensors of pathogen associated dna", "Cytosolic sulfonation of small molecules", "Cytosolic trna aminoacylation", "Dag and ip3 signaling", "Dap12 interactions", "Dap12 signaling", "Darpp 32 events", "Dcc mediated attractive signaling", "Ddx58 ifih1 mediated induction of interferon alpha beta", "Deactivation of the beta catenin transactivating complex", "Deadenylation dependent mrna decay", "Deadenylation of mrna", "Death receptor signalling", "Dectin 1 mediated noncanonical nf kb signaling", "Defective b4galt1 causes b4galt1 cdg cdg 2d", "Defective cftr causes cystic fibrosis", "Defective chst14 causes eds musculocontractural type", "Defective ext2 causes exostoses 2", "Defective factor ix causes hemophilia b", "Defective intrinsic pathway for apoptosis", "Defective lfng causes scdo3", "Defective ripk1 mediated regulated necrosis", "Defects in biotin btn metabolism", "Defects in cobalamin b12 metabolism", "Defects in vitamin and cofactor metabolism", "Defects of contact activation system cas and kallikrein kinin system kks", "Degradation of axin", "Degradation of beta catenin by the destruction complex", "Degradation of cysteine and homocysteine", "Degradation of dvl", "Degradation of gli1 by the proteasome", "Degradation of the extracellular matrix", "Depolymerisation of the nuclear lamina", "Deposition of new cenpa containing nucleosomes at the centromere", "Dermatan sulfate biosynthesis", "Detoxification of reactive oxygen species", "Deubiquitination", "Developmental biology", "Dex h box helicases activate type i ifn and inflammatory cytokines production", "Digestion", "Digestion and absorption", "Disassembly of the destruction complex and recruitment of axin to the membrane", "Diseases associated with glycosaminoglycan metabolism", "Diseases associated with glycosylation precursor biosynthesis", "Diseases associated with n glycosylation of proteins", "Diseases associated with o glycosylation of proteins", "Diseases of base excision repair", "Diseases of carbohydrate metabolism", "Diseases of dna repair", "Diseases of glycosylation", "Diseases of immune system", "Diseases of metabolism", "Diseases of mismatch repair mmr", "Diseases of mitotic cell cycle", "Diseases of programmed cell death", "Diseases of signal transduction by growth factor receptors and second messengers", "Disinhibition of snare formation", "Disorders of transmembrane transporters", "Displacement of dna glycosylase by apex1", "Dissolution of fibrin clot", "Dna damage bypass", "Dna damage recognition in gg ner", "Dna damage reversal", "Dna damage telomere stress induced senescence", "Dna double strand break repair", "Dna double strand break response", "Dna methylation", "Dna repair", "Dna replication", "Dna replication initiation", "Dna replication pre initiation", "Dna strand elongation", "Dopamine clearance from the synaptic cleft", "Dopamine neurotransmitter release cycle", "Downregulation of erbb2 erbb3 signaling", "Downregulation of erbb2 signaling", "Downregulation of erbb4 signaling", "Downregulation of smad2 3 smad4 transcriptional activity", "Downregulation of tgf beta receptor signaling", "Downstream signal transduction", "Downstream signaling events of b cell receptor bcr", "Downstream signaling of activated fgfr1", "Downstream signaling of activated fgfr2", "Downstream signaling of activated fgfr3", "Downstream signaling of activated fgfr4", "Dscam interactions", "Dual incision in gg ner", "Dual incision in tc ner", "E2f enabled inhibition of pre replication complex formation", "E2f mediated regulation of dna replication", "E3 ubiquitin ligases ubiquitinate target proteins", "Early phase of hiv life cycle", "Ecm proteoglycans", "Effects of pip2 hydrolysis", "Egfr downregulation", "Egfr interacts with phospholipase c gamma", "Egfr transactivation by gastrin", "Egr2 and sox10 mediated initiation of schwann cell myelination", "Elastic fibre formation", "Electric transmission across gap junctions", "Endogenous sterols", "Endosomal sorting complex required for transport escrt", "Endosomal vacuolar pathway", "Energy dependent regulation of mtor by lkb1 ampk", "Enos activation", "Eph ephrin mediated repulsion of cells", "Eph ephrin signaling", "Epha mediated growth cone collapse", "Ephb mediated forward signaling", "Ephrin signaling", "Epigenetic regulation of gene expression", "Er quality control compartment erqc", "Er to golgi anterograde transport", "Erbb2 regulates cell motility", "Ercc6 csb and ehmt2 g9a positively regulate rrna expression", "Erk mapk targets", "Erks are inactivated", "Erythropoietin activates phospholipase c gamma plcg", "Erythropoietin activates ras", "Esr mediated signaling", "Establishment of sister chromatid cohesion", "Estrogen biosynthesis", "Estrogen dependent gene expression", "Estrogen dependent nuclear events downstream of esr membrane signaling", "Estrogen stimulated signaling through prkcz", "Ethanol oxidation", "Eukaryotic translation elongation", "Eukaryotic translation initiation", "Export of viral ribonucleoproteins from nucleus", "Extension of telomeres", "Extra nuclear estrogen signaling", "Extracellular matrix organization", "Factors involved in megakaryocyte development and platelet production", "Fanconi anemia pathway", "Fasl cd95l signaling", "Fatty acid metabolism", "Fatty acids bound to gpr40 ffar1 regulate insulin secretion", "Fatty acyl coa biosynthesis", "Fbxw7 mutants and notch1 in cancer", "Fc epsilon receptor fceri signaling", "Fceri mediated ca 2 mobilization", "Fceri mediated mapk activation", "Fceri mediated nf kb activation", "Fcgamma receptor fcgr dependent phagocytosis", "Fcgr3a mediated il10 synthesis", "Fertilization", "Fgfr1 mutant receptor activation", "Fgfr2 alternative splicing", "Fgfr2 mutant receptor activation", "Fibronectin matrix formation", "Flt3 signaling", "Flt3 signaling in disease", "Folding of actin by cct tric", "Formation of apoptosome", "Formation of atp by chemiosmotic coupling", "Formation of fibrin clot clotting cascade", "Formation of incision complex in gg ner", "Formation of rna pol ii elongation complex", "Formation of senescence associated heterochromatin foci sahf", "Formation of tc ner pre incision complex", "Formation of the beta catenin tcf transactivating complex", "Formation of the cornified envelope", "Formation of the early elongation complex", "Formation of tubulin folding intermediates by cct tric", "Formation of xylulose 5 phosphate", "Formyl peptide receptors bind formyl peptides and many other ligands", "Foxo mediated transcription", "Foxo mediated transcription of oxidative stress metabolic and neuronal genes", "Free fatty acids regulate insulin secretion", "Frs mediated fgfr1 signaling", "Frs mediated fgfr2 signaling", "Frs mediated fgfr3 signaling", "Frs mediated fgfr4 signaling", "Fructose catabolism", "Fructose metabolism", "G alpha 12 13 signalling events", "G alpha i signalling events", "G alpha q signalling events", "G alpha s signalling events", "G alpha z signalling events", "G beta gamma signalling through cdc42", "G beta gamma signalling through pi3kgamma", "G protein activation", "G protein beta gamma signalling", "G protein mediated events", "G0 and early g1", "G1 s dna damage checkpoints", "G1 s specific transcription", "G2 m checkpoints", "G2 m dna damage checkpoint", "G2 m dna replication checkpoint", "G2 phase", "Gab1 signalosome", "Gaba b receptor activation", "Gaba receptor activation", "Gaba synthesis release reuptake and degradation", "Galactose catabolism", "Gamma carboxylation hypusine formation and arylsulfatase activation", "Gamma carboxylation transport and amino terminal cleavage of proteins", "Gap filling dna repair synthesis and ligation in gg ner", "Gap junction assembly", "Gap junction degradation", "Gap junction trafficking and regulation", "Gastrin creb signalling pathway via pkc and mapk", "Gdp fucose biosynthesis", "Gene and protein expression by jak stat signaling after interleukin 12 stimulation", "Gene silencing by rna", "Generation of second messenger molecules", "Global genome nucleotide excision repair gg ner", "Glucagon like peptide 1 glp1 regulates insulin secretion", "Glucagon signaling in metabolic regulation", "Glucagon type ligand receptors", "Gluconeogenesis", "Glucose metabolism", "Glucuronidation", "Glutamate and glutamine metabolism", "Glutamate neurotransmitter release cycle", "Glutathione conjugation", "Glutathione synthesis and recycling", "Glycerophospholipid biosynthesis", "Glycerophospholipid catabolism", "Glycogen breakdown glycogenolysis", "Glycogen metabolism", "Glycogen storage diseases", "Glycogen synthesis", "Glycolysis", "Glycosaminoglycan metabolism", "Glycosphingolipid metabolism", "Glyoxylate metabolism and glycine degradation", "Golgi associated vesicle biogenesis", "Golgi cisternae pericentriolar stack reorganization", "Golgi to er retrograde transport", "Gp1b ix v activation signalling", "Gpcr ligand binding", "Gpvi mediated activation cascade", "Grb2 events in erbb2 signaling", "Grb2 sos provides linkage to mapk signaling for integrins", "Growth hormone receptor signaling", "Hats acetylate histones", "Hcmv early events", "Hcmv infection", "Hcmv late events", "Hdacs deacetylate histones", "Hdl assembly", "Hdl clearance", "Hdms demethylate histones", "Hdr through homologous recombination hrr", "Hdr through mmej alt nhej", "Hdr through single strand annealing ssa", "Hedgehog ligand biogenesis", "Hedgehog off state", "Hedgehog on state", "Heme biosynthesis", "Heme degradation", "Heme signaling", "Hemostasis", "Heparan sulfate heparin hs gag metabolism", "Hiv elongation arrest and recovery", "Hiv infection", "Hiv life cycle", "Hiv transcription elongation", "Hiv transcription initiation", "Homologous dna pairing and strand exchange", "Homology directed repair", "Host interactions of hiv factors", "Hs gag biosynthesis", "Hs gag degradation", "Hsf1 activation", "Hsf1 dependent transactivation", "Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand", "Hur elavl1 binds and stabilizes mrna", "Hyaluronan metabolism", "Hyaluronan uptake and degradation", "Hydrolysis of lpc", "Ikba variant leads to eda id", "Ikk complex recruitment mediated by rip1", "Immunoregulatory interactions between a lymphoid and a non lymphoid cell", "Inactivation of cdc42 and rac1", "Inactivation of csf3 g csf signaling", "Incretin synthesis secretion and inactivation", "Infection with mycobacterium tuberculosis", "Infectious disease", "Inflammasomes", "Influenza infection", "Inhibition of dna recombination at telomere", "Inhibition of replication initiation of damaged dna by rb1 e2f1", "Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components", "Initiation of nuclear envelope ne reformation", "Inla mediated entry of listeria monocytogenes into host cells", "Inlb mediated entry of listeria monocytogenes into host cell", "Innate immune system", "Inositol phosphate metabolism", "Insertion of tail anchored proteins into the endoplasmic reticulum membrane", "Insulin processing", "Insulin receptor recycling", "Insulin receptor signalling cascade", "Integration of energy metabolism", "Integration of provirus", "Integrin cell surface interactions", "Integrin signaling", "Interaction between l1 and ankyrins", "Interaction with cumulus cells and the zona pellucida", "Interactions of rev with host cellular proteins", "Interactions of vpr with host cellular proteins", "Interconversion of nucleotide di and triphosphates", "Interferon alpha beta signaling", "Interferon gamma signaling", "Interferon signaling", "Interleukin 1 family signaling", "Interleukin 1 signaling", "Interleukin 10 signaling", "Interleukin 12 family signaling", "Interleukin 12 signaling", "Interleukin 15 signaling", "Interleukin 17 signaling", "Interleukin 2 family signaling", "Interleukin 20 family signaling", "Interleukin 21 signaling", "Interleukin 23 signaling", "Interleukin 27 signaling", "Interleukin 3 interleukin 5 and gm csf signaling", "Interleukin 35 signalling", "Interleukin 37 signaling", "Interleukin 4 and interleukin 13 signaling", "Interleukin 6 family signaling", "Interleukin 6 signaling", "Interleukin 7 signaling", "Interleukin 9 signaling", "Interleukin receptor shc signaling", "Intra golgi and retrograde golgi to er traffic", "Intra golgi traffic", "Intracellular signaling by second messengers", "Intraflagellar transport", "Intrinsic pathway for apoptosis", "Intrinsic pathway of fibrin clot formation", "Inwardly rectifying k channels", "Ion channel transport", "Ion homeostasis", "Ion transport by p type atpases", "Ionotropic activity of kainate receptors", "Irak1 recruits ikk complex", "Irak2 mediated activation of tak1 complex", "Irak4 deficiency tlr2 4", "Ire1alpha activates chaperones", "Irf3 mediated activation of type 1 ifn", "Irf3 mediated induction of type i ifn", "Iron uptake and transport", "Irs mediated signalling", "Jnk c jun kinases phosphorylation and activation mediated by activated human tak1", "Josephin domain dubs", "Keratan sulfate biosynthesis", "Keratan sulfate degradation", "Keratan sulfate keratin metabolism", "Keratinization", "Ketone body metabolism", "Killing mechanisms", "Kinesins", "Ksrp khsrp binds and destabilizes mrna", "L1cam interactions", "Lagging strand synthesis", "Laminin interactions", "Late endosomal microautophagy", "Ldl clearance", "Ldl remodeling", "Leishmania infection", "Lgi adam interactions", "Linoleic acid la metabolism", "Lipophagy", "Listeria monocytogenes entry into host cells", "Long term potentiation", "Loss of function of mecp2 in rett syndrome", "Loss of mecp2 binding ability to the ncor smrt complex", "Lrr flii interacting protein 1 lrrfip1 activates type i ifn production", "Lysine catabolism", "Lysosome vesicle biogenesis", "M phase", "Map2k and mapk activation", "Map3k8 tpl2 dependent mapk1 3 activation", "Mapk family signaling cascades", "Mapk targets nuclear events mediated by map kinases", "Mapk1 erk2 activation", "Mapk3 erk1 activation", "Mapk6 mapk4 signaling", "Mastl facilitates mitotic progression", "Maturation of protein 3a", "Maturation of sars cov 1 nucleoprotein", "Maturation of sars cov 1 spike protein", "Maturation of sars cov 2 nucleoprotein", "Maturation of sars cov 2 spike protein", "Mecp2 regulates neuronal receptors and channels", "Mecp2 regulates transcription factors", "Mecp2 regulates transcription of neuronal ligands", "Meiosis", "Meiotic recombination", "Meiotic synapsis", "Membrane trafficking", "Met activates pi3k akt signaling", "Met activates ptk2 signaling", "Met activates ptpn11", "Met activates rap1 and rac1", "Met activates ras signaling", "Met interacts with tns proteins", "Met promotes cell motility", "Met receptor activation", "Met receptor recycling", "Metabolic disorders of biological oxidation enzymes", "Metabolism of amino acids and derivatives", "Metabolism of angiotensinogen to angiotensins", "Metabolism of carbohydrates", "Metabolism of cofactors", "Metabolism of fat soluble vitamins", "Metabolism of folate and pterines", "Metabolism of ingested semet sec mesec into h2se", "Metabolism of lipids", "Metabolism of nitric oxide nos3 activation and regulation", "Metabolism of nucleotides", "Metabolism of polyamines", "Metabolism of porphyrins", "Metabolism of rna", "Metabolism of steroid hormones", "Metabolism of steroids", "Metabolism of vitamins and cofactors", "Metabolism of water soluble vitamins and cofactors", "Metal ion slc transporters", "Metalloprotease dubs", "Methionine salvage pathway", "Methylation", "Mhc class ii antigen presentation", "Microrna mirna biogenesis", "Miro gtpase cycle", "Miscellaneous transport and binding events", "Mismatch repair", "Mitochondrial biogenesis", "Mitochondrial calcium ion transport", "Mitochondrial fatty acid beta oxidation", "Mitochondrial fatty acid beta oxidation of saturated fatty acids", "Mitochondrial fatty acid beta oxidation of unsaturated fatty acids", "Mitochondrial iron sulfur cluster biogenesis", "Mitochondrial protein import", "Mitochondrial translation", "Mitochondrial trna aminoacylation", "Mitophagy", "Mitotic g1 phase and g1 s transition", "Mitotic g2 g2 m phases", "Mitotic metaphase and anaphase", "Mitotic prometaphase", "Mitotic prophase", "Mitotic spindle checkpoint", "Mitotic telophase cytokinesis", "Molecules associated with elastic fibres", "Molybdenum cofactor biosynthesis", "Mrna capping", "Mrna decay by 3 to 5 exoribonuclease", "Mrna decay by 5 to 3 exoribonuclease", "Mrna editing", "Mrna editing c to u conversion", "Mrna splicing", "Mrna splicing minor pathway", "Mtor signalling", "Mtorc1 mediated signalling", "Mucopolysaccharidoses", "Muscle contraction", "Myd88 independent tlr4 cascade", "Myoclonic epilepsy of lafora", "Myogenesis", "N glycan antennae elongation", "N glycan antennae elongation in the medial trans golgi", "N glycan trimming and elongation in the cis golgi", "N glycan trimming in the er and calnexin calreticulin cycle", "Nade modulates death signalling", "Ncam signaling for neurite out growth", "Nectin necl trans heterodimerization", "Neddylation", "Nef and signal transduction", "Nef mediated cd4 down regulation", "Nef mediated cd8 down regulation", "Nef mediated downregulation of mhc class i complex cell surface expression", "Nef mediates down modulation of cell surface receptors by recruiting them to clathrin adapters", "Negative epigenetic regulation of rrna expression", "Negative feedback regulation of mapk pathway", "Negative regulation of fgfr1 signaling", "Negative regulation of fgfr2 signaling", "Negative regulation of fgfr3 signaling", "Negative regulation of fgfr4 signaling", "Negative regulation of flt3", "Negative regulation of mapk pathway", "Negative regulation of met activity", "Negative regulation of nmda receptor mediated neuronal transmission", "Negative regulation of notch4 signaling", "Negative regulation of tcf dependent signaling by dvl interacting proteins", "Negative regulation of the pi3k akt network", "Negative regulators of ddx58 ifih1 signaling", "Nephrin family interactions", "Nervous system development", "Netrin 1 signaling", "Netrin mediated repulsion signals", "Neurexins and neuroligins", "Neurofascin interactions", "Neuronal system", "Neurotoxicity of clostridium toxins", "Neurotransmitter clearance", "Neurotransmitter receptors and postsynaptic signal transmission", "Neurotransmitter release cycle", "Neutrophil degranulation", "Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10", "Nf kb is activated and signals survival", "Ngf stimulated transcription", "Nicotinamide salvaging", "Nicotinate metabolism", "Nod1 2 signaling pathway", "Non integrin membrane ecm interactions", "Noncanonical activation of notch3", "Nonhomologous end joining nhej", "Nonsense mediated decay nmd", "Norepinephrine neurotransmitter release cycle", "Nostrin mediated enos trafficking", "Notch hlh transcription pathway", "Notch1 intracellular domain regulates transcription", "Notch2 activation and transmission of signal to the nucleus", "Notch2 intracellular domain regulates transcription", "Notch3 activation and transmission of signal to the nucleus", "Notch3 intracellular domain regulates transcription", "Notch4 activation and transmission of signal to the nucleus", "Notch4 intracellular domain regulates transcription", "Nr1h2 and nr1h3 mediated signaling", "Nr1h2 nr1h3 regulate gene expression linked to lipogenesis", "Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux", "Nrage signals death through jnk", "Nrcam interactions", "Nrif signals cell death from the nucleus", "Ns1 mediated effects on host pathways", "Ntrk2 activates rac1", "Nuclear envelope breakdown", "Nuclear envelope ne reassembly", "Nuclear events kinase and transcription factor activation", "Nuclear events stimulated by alk signaling in cancer", "Nuclear import of rev protein", "Nuclear pore complex npc disassembly", "Nuclear receptor transcription pathway", "Nuclear signaling by erbb4", "Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways", "Nucleotide biosynthesis", "Nucleotide catabolism", "Nucleotide excision repair", "Nucleotide salvage", "O glycosylation of tsr domain containing proteins", "O linked glycosylation", "O linked glycosylation of mucins", "Oas antiviral response", "Oncogene induced senescence", "Oncogenic mapk signaling", "Opioid signalling", "Orc1 removal from chromatin", "Organelle biogenesis and maintenance", "Organic anion transporters", "Other interleukin signaling", "Other semaphorin interactions", "Ovarian tumor domain proteases", "Oxidative stress induced senescence", "P130cas linkage to mapk signaling for integrins", "P38mapk events", "P75 ntr receptor mediated signalling", "P75ntr negatively regulates cell cycle via sc1", "P75ntr recruits signalling complexes", "P75ntr regulates axonogenesis", "P75ntr signals via nf kb", "Parasite infection", "Passive transport by aquaporins", "Pcna dependent long patch base excision repair", "Pcp ce pathway", "Pd 1 signaling", "Pecam1 interactions", "Pentose phosphate pathway", "Peptide hormone metabolism", "Peptide ligand binding receptors", "Perk regulates gene expression", "Peroxisomal lipid metabolism", "Peroxisomal protein import", "Pexophagy", "Phase 0 rapid depolarisation", "Phase i functionalization of compounds", "Phase ii conjugation of compounds", "Phenylalanine and tyrosine metabolism", "Phenylalanine metabolism", "Phosphate bond hydrolysis by nudt proteins", "Phospholipase c mediated cascade fgfr2", "Phospholipase c mediated cascade fgfr4", "Phospholipid metabolism", "Phosphorylation of emi1", "Phosphorylation of the apc c", "Pi 3k cascade fgfr1", "Pi 3k cascade fgfr2", "Pi 3k cascade fgfr3", "Pi 3k cascade fgfr4", "Pi metabolism", "Pi3k akt signaling in cancer", "Pi3k events in erbb2 signaling", "Pi5p regulates tp53 acetylation", "Pink1 prkn mediated mitophagy", "Piwi interacting rna pirna biogenesis", "Pka activation in glucagon signalling", "Pka mediated phosphorylation of creb", "Pka mediated phosphorylation of key metabolic factors", "Pkmts methylate histone lysines", "Plasma lipoprotein assembly", "Plasma lipoprotein assembly remodeling and clearance", "Plasma lipoprotein clearance", "Plasma lipoprotein remodeling", "Platelet activation signaling and aggregation", "Platelet adhesion to exposed collagen", "Platelet aggregation plug formation", "Platelet calcium homeostasis", "Platelet homeostasis", "Platelet sensitization by ldl", "Polb dependent long patch base excision repair", "Polo like kinase mediated events", "Polymerase switching", "Polymerase switching on the c strand of the telomere", "Positive epigenetic regulation of rrna expression", "Post chaperonin tubulin folding pathway", "Post translational modification synthesis of gpi anchored proteins", "Post translational protein modification", "Postmitotic nuclear pore complex npc reformation", "Potassium channels", "Potential therapeutics for sars", "Pou5f1 oct4 sox2 nanog activate genes related to proliferation", "Pp2a mediated dephosphorylation of key metabolic factors", "Prc2 methylates histones and dna", "Pre notch expression and processing", "Pre notch processing in golgi", "Pre notch processing in the endoplasmic reticulum", "Pregnenolone biosynthesis", "Presynaptic function of kainate receptors", "Prevention of phagosomal lysosomal fusion", "Processing and activation of sumo", "Processing of capped intron containing pre mrna", "Processing of capped intronless pre mrna", "Processing of dna double strand break ends", "Processing of intronless pre mrnas", "Processing of smdt1", "Processive synthesis on the c strand of the telomere", "Processive synthesis on the lagging strand", "Programmed cell death", "Prolactin receptor signaling", "Prolonged erk activation events", "Propionyl coa catabolism", "Prostacyclin signalling through prostacyclin receptor", "Protein folding", "Protein localization", "Protein methylation", "Protein protein interactions at synapses", "Protein repair", "Protein ubiquitination", "Proton coupled monocarboxylate transport", "Pten regulation", "Ptk6 expression", "Ptk6 regulates cell cycle", "Ptk6 regulates proteins involved in rna processing", "Ptk6 regulates rho gtpases ras gtpase and map kinases", "Ptk6 regulates rtks and their effectors akt1 and dok1", "Purine catabolism", "Purine ribonucleoside monophosphate biosynthesis", "Purine salvage", "Purinergic signaling in leishmaniasis infection", "Pyrimidine catabolism", "Pyrimidine salvage", "Pyroptosis", "Pyruvate metabolism", "Pyruvate metabolism and citric acid tca cycle", "Ra biosynthesis pathway", "Rab gefs exchange gtp for gdp on rabs", "Rab geranylgeranylation", "Rab regulation of trafficking", "Rac1 gtpase cycle", "Rac2 gtpase cycle", "Rac3 gtpase cycle", "Raf activation", "Raf independent mapk1 3 activation", "Rap1 signalling", "Ras activation upon ca2 influx through nmda receptor", "Ras processing", "Reactions specific to the complex n glycan synthesis pathway", "Receptor mediated mitophagy", "Receptor type tyrosine protein phosphatases", "Recognition and association of dna glycosylase with site containing an affected purine", "Recognition of dna damage by pcna containing replication complex", "Recruitment of mitotic centrosome proteins and complexes", "Recruitment of numa to mitotic centrosomes", "Recycling of eif2 gdp", "Recycling pathway of l1", "Reduction of cytosolic ca levels", "Regulated necrosis", "Regulated proteolysis of p75ntr", "Regulation by c flip", "Regulation of bach1 activity", "Regulation of beta cell development", "Regulation of cholesterol biosynthesis by srebp srebf", "Regulation of commissural axon pathfinding by slit and robo", "Regulation of cytoskeletal remodeling and cell spreading by ipp complex components", "Regulation of expression of slits and robos", "Regulation of foxo transcriptional activity by acetylation", "Regulation of fzd by ubiquitination", "Regulation of gene expression by hypoxia inducible factor", "Regulation of gene expression in beta cells", "Regulation of gene expression in early pancreatic precursor cells", "Regulation of gene expression in late stage branching morphogenesis pancreatic bud precursor cells", "Regulation of glucokinase by glucokinase regulatory protein", "Regulation of glycolysis by fructose 2 6 bisphosphate metabolism", "Regulation of hmox1 expression and activity", "Regulation of hsf1 mediated heat shock response", "Regulation of ifna signaling", "Regulation of ifng signaling", "Regulation of innate immune responses to cytosolic dna", "Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps", "Regulation of insulin secretion", "Regulation of kit signaling", "Regulation of lipid metabolism by pparalpha", "Regulation of localization of foxo transcription factors", "Regulation of mecp2 expression and activity", "Regulation of mrna stability by proteins that bind au rich elements", "Regulation of plk1 activity at g2 m transition", "Regulation of pten gene transcription", "Regulation of pten localization", "Regulation of pten mrna translation", "Regulation of pten stability and activity", "Regulation of pyruvate dehydrogenase pdh complex", "Regulation of ras by gaps", "Regulation of runx1 expression and activity", "Regulation of runx2 expression and activity", "Regulation of runx3 expression and activity", "Regulation of signaling by cbl", "Regulation of tlr by endogenous ligand", "Regulation of tnfr1 signaling", "Regulation of tp53 activity", "Regulation of tp53 activity through acetylation", "Regulation of tp53 activity through association with co factors", "Regulation of tp53 activity through methylation", "Regulation of tp53 activity through phosphorylation", "Regulation of tp53 expression and degradation", "Release of apoptotic factors from the mitochondria", "Release of hh np from the secreting cell", "Repression of wnt target genes", "Reproduction", "Resolution of abasic sites ap sites", "Resolution of ap sites via the multiple nucleotide patch replacement pathway", "Resolution of d loop structures", "Resolution of d loop structures through synthesis dependent strand annealing sdsa", "Resolution of sister chromatid cohesion", "Respiratory electron transport", "Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins", "Response of eif2ak1 hri to heme deficiency", "Response of eif2ak4 gcn2 to amino acid deficiency", "Response of mtb to phagocytosis", "Response to elevated platelet cytosolic ca2", "Ret signaling", "Retrograde neurotrophin signalling", "Retrograde transport at the trans golgi network", "Rho gtpase cycle", "Rho gtpase effectors", "Rho gtpases activate cit", "Rho gtpases activate formins", "Rho gtpases activate iqgaps", "Rho gtpases activate ktn1", "Rho gtpases activate nadph oxidases", "Rho gtpases activate paks", "Rho gtpases activate pkns", "Rho gtpases activate rocks", "Rho gtpases activate wasps and waves", "Rhoa gtpase cycle", "Rhob gtpase cycle", "Rhobtb gtpase cycle", "Rhobtb1 gtpase cycle", "Rhobtb2 gtpase cycle", "Rhobtb3 atpase cycle", "Rhoc gtpase cycle", "Rhod gtpase cycle", "Rhof gtpase cycle", "Rhog gtpase cycle", "Rhoh gtpase cycle", "Rhoj gtpase cycle", "Rhoq gtpase cycle", "Rhot1 gtpase cycle", "Rhou gtpase cycle", "Rhov gtpase cycle", "Rip mediated nfkb activation via zbp1", "Ripk1 mediated regulated necrosis", "Rmts methylate histone arginines", "Rna polymerase i promoter escape", "Rna polymerase i transcription", "Rna polymerase i transcription initiation", "Rna polymerase i transcription termination", "Rna polymerase ii transcribes snrna genes", "Rna polymerase ii transcription", "Rna polymerase ii transcription termination", "Rna polymerase iii chain elongation", "Rna polymerase iii transcription", "Rna polymerase iii transcription initiation from type 1 promoter", "Rna polymerase iii transcription initiation from type 3 promoter", "Rna polymerase iii transcription termination", "Rnd1 gtpase cycle", "Rnd2 gtpase cycle", "Rnd3 gtpase cycle", "Robo receptors bind akap5", "Role of abl in robo slit signaling", "Role of lat2 ntal lab on calcium mobilization", "Role of phospholipids in phagocytosis", "Role of second messengers in netrin 1 signaling", "Rora activates gene expression", "Ros and rns production in phagocytes", "Rrna modification in the mitochondrion", "Rrna modification in the nucleus and cytosol", "Rrna processing", "Rrna processing in the mitochondrion", "Rsk activation", "Runx1 interacts with co factors whose precise effect on runx1 targets is not known", "Runx1 regulates estrogen receptor mediated transcription", "Runx1 regulates expression of components of tight junctions", "Runx1 regulates genes involved in megakaryocyte differentiation and platelet function", "Runx1 regulates transcription of genes involved in differentiation of hscs", "Runx1 regulates transcription of genes involved in differentiation of myeloid cells", "Runx2 regulates bone development", "Runx2 regulates genes involved in cell migration", "Runx2 regulates osteoblast differentiation", "Runx3 regulates cdkn1a transcription", "Runx3 regulates notch signaling", "Runx3 regulates p14 arf", "Runx3 regulates wnt signaling", "S phase", "Sars cov 1 infection", "Sars cov 2 infection", "Sars cov infections", "Scavenging by class a receptors", "Scavenging by class b receptors", "Scavenging by class f receptors", "Scf skp2 mediated degradation of p27 p21", "Sealing of the nuclear envelope ne by escrt iii", "Selective autophagy", "Selenoamino acid metabolism", "Sema3a pak dependent axon repulsion", "Sema3a plexin repulsion signaling by inhibiting integrin adhesion", "Sema4d in semaphorin signaling", "Sema4d induced cell migration and growth cone collapse", "Sema4d mediated inhibition of cell attachment and migration", "Semaphorin interactions", "Senescence associated secretory phenotype sasp", "Sensing of dna double strand breaks", "Sensory perception", "Sensory processing of sound", "Sensory processing of sound by outer hair cells of the cochlea", "Separation of sister chromatids", "Serine biosynthesis", "Serotonin neurotransmitter release cycle", "Shc mediated cascade fgfr1", "Shc mediated cascade fgfr3", "Shc mediated cascade fgfr4", "Shc related events triggered by igf1r", "Shc1 events in egfr signaling", "Shc1 events in erbb2 signaling", "Shc1 events in erbb4 signaling", "Sialic acid metabolism", "Signal amplification", "Signal attenuation", "Signal regulatory protein family interactions", "Signal transduction by l1", "Signaling by activin", "Signaling by alk", "Signaling by alk in cancer", "Signaling by bmp", "Signaling by braf and raf1 fusions", "Signaling by csf3 g csf", "Signaling by ctnnb1 phospho site mutants", "Signaling by cytosolic fgfr1 fusion mutants", "Signaling by egfr", "Signaling by egfr in cancer", "Signaling by erbb2", "Signaling by erbb2 ecd mutants", "Signaling by erbb2 in cancer", "Signaling by erbb4", "Signaling by erythropoietin", "Signaling by fgfr", "Signaling by fgfr in disease", "Signaling by fgfr1", "Signaling by fgfr1 in disease", "Signaling by fgfr2", "Signaling by fgfr2 iiia tm", "Signaling by fgfr2 in disease", "Signaling by fgfr3", "Signaling by fgfr3 fusions in cancer", "Signaling by fgfr4", "Signaling by fgfr4 in disease", "Signaling by flt3 fusion proteins", "Signaling by flt3 itd and tkd mutants", "Signaling by gpcr", "Signaling by hedgehog", "Signaling by hippo", "Signaling by insulin receptor", "Signaling by interleukins", "Signaling by kit in disease", "Signaling by leptin", "Signaling by mapk mutants", "Signaling by met", "Signaling by moderate kinase activity braf mutants", "Signaling by mras complex mutants", "Signaling by mst1", "Signaling by nodal", "Signaling by notch", "Signaling by notch1", "Signaling by notch1 hd domain mutants in cancer", "Signaling by notch1 pest domain mutants in cancer", "Signaling by notch1 t 7 9 notch1 m1580 k2555 translocation mutant", "Signaling by notch2", "Signaling by notch3", "Signaling by notch4", "Signaling by ntrk2 trkb", "Signaling by ntrk3 trkc", "Signaling by ntrks", "Signaling by nuclear receptors", "Signaling by pdgf", "Signaling by pdgfr in disease", "Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants", "Signaling by ptk6", "Signaling by receptor tyrosine kinases", "Signaling by retinoic acid", "Signaling by rho gtpases miro gtpases and rhobtb3", "Signaling by robo receptors", "Signaling by scf kit", "Signaling by tgf beta receptor complex", "Signaling by tgf beta receptor complex in cancer", "Signaling by tgfb family members", "Signaling by the b cell receptor bcr", "Signaling by type 1 insulin like growth factor 1 receptor igf1r", "Signaling by vegf", "Signaling by wnt", "Signaling by wnt in cancer", "Signalling to erks", "Signalling to ras", "Sirt1 negatively regulates rrna expression", "Slbp dependent processing of replication dependent histone pre mrnas", "Slc mediated transmembrane transport", "Slc transporter disorders", "Smac xiap regulated apoptotic response", "Smad2 smad3 smad4 heterotrimer regulates transcription", "Small interfering rna sirna biogenesis", "Smooth muscle contraction", "Snrnp assembly", "Sodium calcium exchangers", "Sos mediated signalling", "Sphingolipid de novo biosynthesis", "Sphingolipid metabolism", "Spry regulation of fgf signaling", "Srp dependent cotranslational protein targeting to membrane", "Stabilization of p53", "Stat3 nuclear events downstream of alk signaling", "Stat5 activation", "Stat5 activation downstream of flt3 itd mutants", "Stimuli sensing channels", "Sting mediated induction of host immune responses", "Striated muscle contraction", "Sulfide oxidation to sulfate", "Sulfur amino acid metabolism", "Sumo is conjugated to e1 uba2 sae1", "Sumo is proteolytically processed", "Sumo is transferred from e1 to e2 ube2i ubc9", "Sumoylation", "Sumoylation of chromatin organization proteins", "Sumoylation of dna damage response and repair proteins", "Sumoylation of dna methylation proteins", "Sumoylation of dna replication proteins", "Sumoylation of intracellular receptors", "Sumoylation of rna binding proteins", "Sumoylation of sumoylation proteins", "Sumoylation of transcription cofactors", "Sumoylation of transcription factors", "Sumoylation of ubiquitinylation proteins", "Suppression of apoptosis", "Suppression of phagosomal maturation", "Surfactant metabolism", "Switching of origins to a post replicative state", "Synaptic adhesion like molecules", "Syndecan interactions", "Synthesis of 5 eicosatetraenoic acids", "Synthesis of active ubiquitin roles of e1 and e2 enzymes", "Synthesis of bile acids and bile salts", "Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol", "Synthesis of diphthamide eef2", "Synthesis of dna", "Synthesis of dolichyl phosphate", "Synthesis of epoxy eet and dihydroxyeicosatrienoic acids dhet", "Synthesis of gdp mannose", "Synthesis of glycosylphosphatidylinositol gpi", "Synthesis of ip2 ip and ins in the cytosol", "Synthesis of ip3 and ip4 in the cytosol", "Synthesis of ketone bodies", "Synthesis of leukotrienes lt and eoxins ex", "Synthesis of lipoxins lx", "Synthesis of pa", "Synthesis of pc", "Synthesis of pe", "Synthesis of pg", "Synthesis of pi", "Synthesis of pips at the early endosome membrane", "Synthesis of pips at the er membrane", "Synthesis of pips at the golgi membrane", "Synthesis of pips at the late endosome membrane", "Synthesis of pips at the plasma membrane", "Synthesis of prostaglandins pg and thromboxanes tx", "Synthesis of pyrophosphates in the cytosol", "Synthesis of substrates in n glycan biosythesis", "Synthesis of udp n acetyl glucosamine", "Synthesis of very long chain fatty acyl coas", "Synthesis of wybutosine at g37 of trna phe", "Synthesis secretion and deacylation of ghrelin", "Synthesis secretion and inactivation of glucagon like peptide 1 glp 1", "Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip", "Tak1 activates nfkb by phosphorylation and activation of ikks complex", "Tbc rabgaps", "Tcf dependent signaling in response to wnt", "Tcr signaling", "Telomere c strand lagging strand synthesis", "Telomere c strand synthesis initiation", "Telomere extension by telomerase", "Telomere maintenance", "Terminal pathway of complement", "Termination of translesion dna synthesis", "Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation", "Tfap2 ap 2 family regulates transcription of growth factors and their receptors", "Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation", "Tgf beta receptor signaling activates smads", "Tgf beta receptor signaling in emt epithelial to mesenchymal transition", "The activation of arylsulfatases", "The canonical retinoid cycle in rods twilight vision", "The citric acid tca cycle and respiratory electron transport", "The nlrp3 inflammasome", "The phototransduction cascade", "The role of gtse1 in g2 m progression after g2 checkpoint", "The role of nef in hiv 1 replication and disease pathogenesis", "Thrombin signalling through proteinase activated receptors pars", "Thromboxane signalling through tp receptor", "Ticam1 rip1 mediated ikk complex recruitment", "Ticam1 traf6 dependent induction of tak1 complex", "Tie2 signaling", "Tight junction interactions", "Tlr3 mediated ticam1 dependent programmed cell death", "Tnf signaling", "Tnfr1 induced nfkappab signaling pathway", "Tnfr1 induced proapoptotic signaling", "Tnfr1 mediated ceramide production", "Tnfr2 non canonical nf kb pathway", "Toll like receptor 9 tlr9 cascade", "Toll like receptor cascades", "Toll like receptor tlr1 tlr2 cascade", "Toxicity of botulinum toxin type d botd", "Tp53 regulates metabolic genes", "Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain", "Tp53 regulates transcription of caspase activators and caspases", "Tp53 regulates transcription of cell cycle genes", "Tp53 regulates transcription of cell death genes", "Tp53 regulates transcription of death receptors and ligands", "Tp53 regulates transcription of dna repair genes", "Tp53 regulates transcription of genes involved in cytochrome c release", "Tp53 regulates transcription of genes involved in g1 cell cycle arrest", "Tp53 regulates transcription of genes involved in g2 cell cycle arrest", "Tp53 regulates transcription of several additional cell death genes whose specific roles in p53 dependent apoptosis remain uncertain", "Traf3 dependent irf activation pathway", "Traf6 mediated induction of tak1 complex within tlr4 complex", "Traf6 mediated irf7 activation", "Traf6 mediated irf7 activation in tlr7 8 or 9 signaling", "Traf6 mediated nf kb activation", "Trafficking and processing of endosomal tlr", "Trafficking of ampa receptors", "Trafficking of glur2 containing ampa receptors", "Trafficking of myristoylated proteins to the cilium", "Trans golgi network vesicle budding", "Transcription coupled nucleotide excision repair tc ner", "Transcription of e2f targets under negative control by dream complex", "Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1", "Transcription of the hiv genome", "Transcriptional activation of mitochondrial biogenesis", "Transcriptional activity of smad2 smad3 smad4 heterotrimer", "Transcriptional regulation by e2f6", "Transcriptional regulation by mecp2", "Transcriptional regulation by runx1", "Transcriptional regulation by runx2", "Transcriptional regulation by runx3", "Transcriptional regulation by small rnas", "Transcriptional regulation by the ap 2 tfap2 family of transcription factors", "Transcriptional regulation by tp53", "Transcriptional regulation by ventx", "Transcriptional regulation of granulopoiesis", "Transcriptional regulation of pluripotent stem cells", "Transcriptional regulation of white adipocyte differentiation", "Transferrin endocytosis and recycling", "Translation", "Translation of replicase and assembly of the replication transcription complex", "Translation of sars cov 1 structural proteins", "Translation of sars cov 2 structural proteins", "Translesion synthesis by polh", "Translesion synthesis by polk", "Translesion synthesis by y family dna polymerases bypasses lesions on dna template", "Translocation of slc2a4 glut4 to the plasma membrane", "Transmission across chemical synapses", "Transport and synthesis of paps", "Transport of bile salts and organic acids metal ions and amine compounds", "Transport of connexons to the plasma membrane", "Transport of fatty acids", "Transport of inorganic cations anions and amino acids oligopeptides", "Transport of mature mrnas derived from intronless transcripts", "Transport of mature transcript to cytoplasm", "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane", "Transport of nucleotide sugars", "Transport of small molecules", "Transport of the slbp dependant mature mrna", "Transport of vitamins nucleosides and related molecules", "Transport to the golgi and subsequent modification", "Trif mediated programmed cell death", "Triglyceride biosynthesis", "Triglyceride catabolism", "Triglyceride metabolism", "Tristetraprolin ttp zfp36 binds and destabilizes mrna", "Trna aminoacylation", "Trna modification in the mitochondrion", "Trna modification in the nucleus and cytosol", "Trna processing", "Trna processing in the mitochondrion", "Trna processing in the nucleus", "Trp channels", "Tryptophan catabolism", "Type i hemidesmosome assembly", "Tyrosine catabolism", "Tysnd1 cleaves peroxisomal proteins", "Ub specific processing proteases", "Ubiquinol biosynthesis", "Uch proteinases", "Unblocking of nmda receptors glutamate binding and activation", "Unfolded protein response upr", "Unwinding of dna", "Uptake and actions of bacterial toxins", "Uptake and function of anthrax toxins", "Uptake and function of diphtheria toxin", "Urea cycle", "Vasopressin regulates renal water homeostasis via aquaporins", "Vegfr2 mediated cell proliferation", "Vegfr2 mediated vascular permeability", "Vesicle mediated transport", "Viral messenger rna synthesis", "Visual phototransduction", "Vitamin b1 thiamin metabolism", "Vitamin b2 riboflavin metabolism", "Vitamin b5 pantothenate metabolism", "Vitamin c ascorbate metabolism", "Vitamin d calciferol metabolism", "Vldl assembly", "Vldl clearance", "Vldlr internalisation and degradation", "Vxpx cargo targeting to cilium", "Wax and plasmalogen biosynthesis", "Wnt ligand biogenesis and trafficking", "Wnt mediated activation of dvl", "Wnt5a dependent internalization of fzd2 fzd5 and ror2", "Wnt5a dependent internalization of fzd4", "Zbp1 dai mediated induction of type i ifns", "Zinc efflux and compartmentalization by the slc30 family", "Zinc influx into cells by the slc39 gene family", "Zinc transporters"], "available_proteins": ["AAAS", "AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABHD10", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "ALYREF", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANKFY1", "ANKLE2", "ANLN", "ANO6", "ANP32A", "ANXA1", "ANXA2", "ANXA6", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "APLP2", "APOBEC3C", "APOC1", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP5", "ARMCX3", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3B", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BASP1", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAT2", "BCKDK", "BCR", "BCS1L", "BECN1", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD4", "BRIP1", "BSG", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "C19orf70", "C1QBP", "C1orf35", "C2CD5", "C2orf49", "CAB39", "CABIN1", "CAD", "CADM1", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCAR1", "CCAR2", "CCDC22", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CENPE", "CENPH", "CENPK", "CENPP", "CENPU", "CEP131", "CEP250", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCN3", "CLCN6", "CLCN7", "CLINT1", "CLNS1A", "CLTA", "CLTB", "CLTC", "CLU", "CMAS", "CMPK1", "CNDP2", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COLEC12", "COLGALT1", "COMMD2", "COMMD6", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ3", "COTL1", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CWC27", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDOST", "DDRGK1", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX52", "DDX56", "DDX6", "DEK", "DENND4C", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS4", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX36", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPH1", "DPH2", "DPH5", "DPM1", "DPY30", "DPYSL2", "DPYSL5", "DSC3", "DSE", "DSG2", "DSP", "DST", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECE1", "ECH1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFHD2", "EFTUD2", "EHD1", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC3", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERCC2", "ERCC3", "ERCC6L", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESD", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM3C", "FAM49B", "FAM91A1", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FIP1L1", "FIS1", "FKBP14", "FKBP1A", "FKBP4", "FKBP5", "FKBP8", "FLAD1", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FN3KRP", "FNBP1", "FNTA", "FSCN1", "FTO", "FTSJ3", "FUCA1", "FUCA2", "FUNDC1", "FUS", "FXR1", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GINS2", "GINS3", "GINS4", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLTP", "GM2A", "GMDS", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL3", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP3", "GUSB", "GYG1", "GYS1", "H1F0", "H2AFX", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HINT2", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HUWE1", "HYOU1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IKBKB", "ILF2", "ILK", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INCENP", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS9", "IPO5", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRS4", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITSN2", "IVD", "IWS1", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0391", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LNPEP", "LONP2", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC1", "LRRC41", "LRRC8A", "LRRC8C", "LRSAM1", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LYPLA1", "LZTFL1", "M6PR", "MAD1L1", "MAD2L1", "MAGED2", "MAGT1", "MAIP1", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP2K1", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MARC1", "MARC2", "MARCKS", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "METAP1", "METAP2", "METTL1", "MFAP1", "MFN2", "MGAT1", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIGA1", "MIPEP", "MLEC", "MMAB", "MMGT1", "MMS19", "MOCOS", "MOCS1", "MOGS", "MON1A", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MPV17", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS6", "MRPS7", "MRPS9", "MRRF", "MRS2", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTERF3", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MYBBP1A", "MYDGF", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1C", "MYO6", "NAA16", "NADK2", "NADSYN1", "NAE1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAPA", "NAPG", "NARS", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFS1", "NHLRC2", "NHP2", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOC4L", "NOL11", "NOL6", "NOL9", "NOP10", "NOP14", "NOP2", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUDC", "NUDT1", "NUDT12", "NUDT16", "NUDT21", "NUDT5", "NUDT9", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NXF1", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAX6", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCK2", "PCM1", "PCMT1", "PCNA", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXK", "PDZD11", "PEBP1", "PECR", "PELP1", "PES1", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF5A", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PMF1", "PMPCA", "PMPCB", "PMVK", "PNKP", "PNO1", "PNP", "PNPLA6", "PNPO", "POFUT1", "POFUT2", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPIB", "PPID", "PPIE", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R12A", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R2", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PUS1", "PUS7", "PWP2", "PXMP2", "PXMP4", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM14", "RBM17", "RBM22", "RBM28", "RBM4", "RBM5", "RBM8A", "RBMX", "RCC1", "RCC2", "RCL1", "RCN1", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "REPS1", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFT1", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMI1", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP36", "RRP7A", "RRP8", "RRP9", "RSF1", "RSU1", "RTCB", "RTF1", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SC5D", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCO1", "SCO2", "SCOC", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEH1L", "SEL1L", "SENP3", "SEPT2", "SEPT7", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A4", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A10", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLIT2", "SLK", "SLTM", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMDT1", "SMG1", "SMG8", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMYD3", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX2", "SNX3", "SNX5", "SNX9", "SOAT1", "SOD2", "SORBS3", "SORD", "SORT1", "SPAG9", "SPAST", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRN", "STT3A", "STUB1", "STX10", "STX18", "STX4", "STX5", "STX6", "STXBP2", "STXBP3", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SURF4", "SUZ12", "SV2A", "SYMPK", "SYNE2", "SYS1", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAP1", "TAPBP", "TARS", "TARS2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL3", "TCEA1", "TCP1", "TCTN3", "TDRKH", "TECR", "TERF2IP", "TEX10", "TEX264", "TFAM", "TFB1M", "TFG", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM126B", "TMEM30A", "TMEM59", "TMEM87A", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMX3", "TNFAIP8", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPX2", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT6", "TRMT61A", "TRMU", "TRRAP", "TSFM", "TSG101", "TSN", "TSNAX", "TSPO", "TSR1", "TSTA3", "TTC26", "TTC37", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXNDC5", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBIAD1", "UBQLN1", "UBR4", "UBTF", "UBXN1", "UCHL5", "UCK2", "UFD1", "UFL1", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119B", "UNG", "UPF1", "UPF2", "UPF3B", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIM", "VKORC1L1", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "WAPL", "WARS", "WARS2", "WASF2", "WBP11", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR75", "WDR77", "WDR91", "WFS1", "WLS", "WNK1", "WRN", "WTAP", "XAB2", "XPO1", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YKT6", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZC3H11A", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCRB1", "ZFYVE16", "ZMYM2", "ZNF512B", "ZNF638", "ZW10", "ZWILCH"], "leading_proteins": ["AAMP", "AASDHPPT", "ABAT", "ABCB7", "ABCD4", "ABI1", "ACAT2", "ACBD3", "ACOX3", "ACP6", "ACSL1", "ACTN1", "ACTN4", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD3", "AFG3L2", "AGPS", "AHCYL1", "AKAP12", "AKT1", "AKT2", "ALDH1A2", "ALDH1B1", "AMOT", "ANAPC7", "ANKLE2", "AP2M1", "APLP2", "APP", "ARHGAP1", "ARHGAP10", "ARHGEF1", "ARIH1", "ASNA1", "ASNS", "ATP13A1", "ATP2A2", "ATP5A1", "ATP5L", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "B3GALT6", "B4GALT1", "B4GALT3", "B4GAT1", "BAG6", "BAIAP2", "BBS4", "BCR", "BECN1", "BICD2", "BSG", "BUB1B", "CADM1", "CAMK1", "CAMK2G", "CANT1", "CAPN5", "CASK", "CCDC22", "CCT2", "CD320", "CD47", "CDC20", "CDC37", "CDC42BPB", "CDC45", "CDH2", "CDK1", "CDK2", "CDK4", "CENPH", "CENPK", "CEP131", "CEP250", "CEP290", "CEPT1", "CERS1", "CERS2", "CHCHD3", "CHKA", "CHST14", "CHUK", "CKAP4", "CLCN3", "CLCN7", "CLTC", "COG3", "COG6", "COLEC12", "COMMD6", "COPB2", "COPG1", "COPS2", "COPS3", "COPS4", "COPS7A", "COPS7B", "COX15", "COX2", "COX5A", "CPD", "CPT2", "CRTAP", "CSK", "CSNK1A1", "CSNK2B", "CTH", "CTNNA1", "CTNNB1", "CTSA", "CYFIP1", "CYFIP2", "CYP51A1", "DCTN1", "DCTN3", "DCUN1D4", "DDRGK1", "DHCR24", "DHX9", "DIAPH3", "DIDO1", "DOCK1", "DOCK7", "ECE1", "EEA1", "EED", "EIF2S1", "EIF2S3", "ELMO2", "EMD", "EML4", "EPHX1", "EPS15", "ERAP1", "ERBIN", "ERCC6L", 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"results/proteins/hek293t_core/msigdb_wp/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/msigdb_wp/result.tsv b/msigdb_wp/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..37fb6b535703831711325ab5e774a94ced07c5e4 --- /dev/null +++ b/msigdb_wp/result.tsv @@ -0,0 +1,170 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Overlap between signal transduction pathways contributing to lmna laminopathies 0.6846272837315815 2.234048856353487 0.0254798585973479 0.9999998546550564 0.2506889313610037 15 P11802,P48729,P49354,Q9Y2U8,P02545,P42166,O75844,O60725,P35222 9 +Cholesterol biosynthesis with skeletal dysplasias 0.8697236484380141 2.1565679200130976 0.0310393463531952 0.9999999955665002 0.2861373873205559 6 Q9UBM7,Q16850,Q15392 3 +Onecarbon metabolism and related pathways 0.6507466903106454 2.1516084653079184 0.0314282048368479 0.9999999965293636 0.2861373873205559 16 P00390,P35790,Q9Y6K0,O43865 4 +Ethanol effects on histone modifications 0.7139849084129284 2.089398629532423 0.0366718544979904 0.9999999998734412 0.3082862638162871 11 O94788 1 +Vitamin a and carotenoid metabolism 0.9115617894867968 2.0135957958730444 0.0440519881927614 0.9999999999988388 0.3237555758745119 4 Q8WTV0 1 +Splicing factor nova regulated synaptic proteins 0.5869461251187409 2.000014898908887 0.0454986551073461 0.999999999999539 0.3251248009817419 18 Q06481,Q9BY67,Q13555,Q9UNS2,Q13573 5 +Striated muscle contraction pathway 0.8183294969726217 1.9487497430180771 0.05132531819908 0.999999999999989 0.3557777738799866 6 P08670,P09493,P67936,O43707 4 +Mammary gland development pathway pregnancy and lactation stage 3 of 4 0.7649427652124379 1.9082269755872967 0.0563618865205017 0.9999999999999996 0.3778104481044624 7 P06753,P22466 2 +Familial partial lipodystrophy fpld 0.7335457206943092 1.878773013660477 0.060275493347099 1.0 0.3781340666767559 8 P20700,P49354,Q03252,P02545,P31751,O75844 6 +Ketogenesis and ketolysis 0.7554695904740663 1.8674262405185016 0.0618420882252466 1.0 0.3781340666767559 7 P23786,P53985,O43772 3 +Acquired partial lipodystrophy barraquersimons syndrome 0.8350742166025205 1.8602033539516272 0.0628567607250061 1.0 0.3781340666767559 5 P02545,P20700,P49354,Q03252 4 +Copper homeostasis 0.7285545879401001 1.8564464784805104 0.0633899450779098 1.0 0.3781340666767559 8 P05067 1 +Inclusion body myositis 0.89286111879801 1.8522227417575112 0.0639938444197558 1.0 0.3781340666767559 3 P05067 1 +Ccl18 signaling pathway 0.6616764504822406 1.8309460836233755 0.0671085909828936 1.0 0.3788793145005858 11 P11166,P33176,P08670,Q96GC9,P42224,P07196,P00403 7 +Metabolism of spingolipids in er and golgi apparatus 0.7461164565178457 1.8269892501435137 0.0677013857058423 1.0 0.3788793145005858 7 Q10472,P15291,Q16739,Q9NRA0 4 +Sars coronavirus and innate immunity 0.7843998901400696 1.7974033933090938 0.0722716024362055 1.0 0.393554949205465 2 Q7Z434 1 +Progeriaassociated lipodystrophy 0.6496144050960718 1.7704045585864652 0.0766597709039436 1.0 0.408146034195416 11 P02545,O75844,P49354,Q03252 4 +Fas ligand pathway and stress induction of heat shock proteins 0.6258225882026609 1.7423942538885633 0.0814394806952036 1.0 0.4175908558022475 13 P02545,Q13813,Q03252 3 +Vitamin dsensitive calcium signaling in depression 0.7266256821451111 1.7422515019407303 0.0814644456401105 1.0 0.4175908558022475 7 P00390 1 +Folate metabolism 0.5681379269434842 1.6763470008660943 0.0936702436309144 1.0 0.4603322365256293 16 Q8WTV0,P41440,P32929 3 +Influence of laminopathies on wnt signaling 0.6293844891708678 1.6681315201905516 0.0952896212484266 1.0 0.4603322365256293 11 P48729,P49354,P02545,O75844,O60725,P35222 6 +Urea cycle and related diseases 0.7544630595990092 1.6653664814543634 0.0958396623586146 1.0 0.4603322365256293 2 Q9Y619 1 +Intracellular trafficking proteins involved in cmt neuropathy 0.6823690143039363 1.647721568754612 0.0994098199169823 1.0 0.4698633358099804 8 Q9NR77 1 +Metapathway biotransformation phase i and ii 0.5098907183087059 1.6438906299552638 0.1001987959968342 1.0 0.4698633358099804 26 P00390,Q16850,P07099 3 +Sterol regulatory elementbinding proteins srebp signaling 0.4579539885507916 1.6324964520147054 0.1025749452919784 1.0 0.4704565160008032 37 Q8WTV0,Q16850,Q9HCL2,Q15437 4 +Ovarian infertility 0.7429277670969487 1.614229748193119 0.1064776016721404 1.0 0.4807898354303015 2 P11802 1 +Oxidation by cytochrome p450 0.7622527305762148 1.5669016946875771 0.1171376714990275 1.0 0.5067658128681333 5 Q16850 1 +Adipogenesis 0.5743396166046636 1.5410517985304035 0.1233041797693719 1.0 0.5223302059674783 14 P43490,O75844,P14174 3 +Endothelin pathways 0.6568323310849582 1.5308384931225356 0.1258093135310709 1.0 0.5284703764729957 8 P42892 1 +Alzheimers disease 0.3851896289745172 1.5178354748777954 0.1290558796361804 1.0 0.5284703764729957 88 P21796,P28070,P28074,P16615,P20618,P45880,P05067,Q14457,P28072,P78536,Q99436,P60900,Q92542,P49721 14 +15q112 copy number variation syndrome 0.7775380839856232 1.4912023809690818 0.1359083687633946 1.0 0.5300358898560017 4 Q7L576,Q96CW5 2 +Proteasome degradation 0.4244471717838863 1.4709743974869494 0.1412980408990378 1.0 0.5300358898560017 43 O00231,P28070,P28074,P30511,P20618,P49721,P28072,Q99436,P60900 9 +Regulation of actin cytoskeleton 0.4311964392861783 1.444489343637907 0.1486013751512718 1.0 0.5427954421693162 39 Q9UQB8,P12814,P26038,P35580,Q13464,O75116,Q96F07,Q9UBI6,Q92888,Q14185 10 +Methionine metabolism leading to sulfur amino acids and related disorders 0.7280115545390916 1.4271480910851604 0.1535372131098706 1.0 0.5567688400771718 5 P55263 1 +Selenium micronutrient network 0.5534364770093658 1.4246709135352635 0.1542523507754787 1.0 0.5567688400771718 14 Q8WTV0,P00390 2 +Hair follicle development cytodifferentiation part 3 of 3 0.7586338547757181 1.4162231269652092 0.1567101867249278 1.0 0.5600371277904485 4 P78536,Q9BZE4 2 +Spinal cord injury 0.4881702944860816 1.3830606471534916 0.1666462708519343 1.0 0.5741205167160771 19 P08670,P14174 2 +Alzheimers disease and mirna effects 0.3716212226700897 1.3622050561952928 0.1731331805964002 1.0 0.575400913161594 91 P21796,P28070,P28074,P16615,P20618,P45880,P05067,Q14457,P28072,P78536,Q99436,P60900,Q92542,P49721 14 +Ebola virus infection in host 0.410443276161502 1.3456167327597492 0.178426152496737 1.0 0.575400913161594 43 P46940,P12814,P10321,O15118,P61916,O75569,P42566,P30511,O43707,P04439,P78536,P41440,P31749 13 +Tryptophan metabolism 0.5258983002225895 1.3437881486443213 0.1790169029432433 1.0 0.575400913161594 15 O94788 1 +Vitamin d metabolism 0.7615384615384623 1.340242509548608 0.1801665154325646 1.0 0.575400913161594 3 Q9UBM7,P04062 2 +Caloric restriction and aging 0.701447683560211 1.318259433035335 0.1874168159920213 1.0 0.590419788968786 5 P43490 1 +Glycerophospholipid biosynthetic pathway 0.5670562361010738 1.3144582753915932 0.1886920305375024 1.0 0.590419788968786 10 O00116,Q8WUK0,Q9HCL2,Q9Y6K0 4 +Proteoglycan biosynthesis 0.6242426751513511 1.2888035835956468 0.1974663798779063 1.0 0.5966639059572355 7 Q96L58,Q8NCH0,Q8WVQ1,Q9NX62 4 +Robo4 and vegf signaling pathways crosstalk 0.6698709145839009 1.288466033523344 0.1975837852514119 1.0 0.5966639059572355 2 O94813 1 +Microglia pathogen phagocytosis pathway 0.6698709145839008 1.2884660335233429 0.1975837852514124 1.0 0.5966639059572355 2 O00443 1 +Mrna protein and metabolite inducation pathway by cyclosporin a 0.716625839071958 1.2492228216782706 0.2115835870705349 1.0 0.6158436044238204 4 Q15758,Q01650 2 +Vitamin b12 metabolism 0.5935820027666673 1.2382735850187654 0.215614634801236 1.0 0.6158436044238204 8 Q8WTV0 1 +Degradation pathway of sphingolipids including diseases 0.6486673654774504 1.23709975322825 0.2160500513880288 1.0 0.6158436044238204 6 P06280,O43681 2 +Regulation of sister chromatid separation at the metaphaseanaphase transition 0.5385734149772027 1.200330133178842 0.2300111513198748 1.0 0.634872408620469 11 Q9UQE7,Q9Y6D9,Q8WVM7,Q12834 4 +Sphingolipid metabolism integrated pathway 0.541906766762211 1.186742331099859 0.2353292722308255 1.0 0.6351807790301044 10 P27544,Q16739,O95470,Q96G23,Q9NRA0 5 +Sphingolipid metabolism overview 0.541906766762211 1.186742331099859 0.2353292722308255 1.0 0.6351807790301044 10 P27544,Q16739,O95470,Q96G23,Q9NRA0 5 +Regulation of wnt bcatenin signaling by small molecule compounds 0.6990914277083029 1.1795555165341522 0.2381770440101855 1.0 0.6372280563430404 4 P48729 1 +H19 action rbe2f1 signaling and cdkbetacatenin activity 0.6638379142097807 1.1639543481640335 0.2444425128878626 1.0 0.6427152278517079 5 P11802,P35222,Q16527 3 +Extracellular vesiclemediated signaling in recipient cells 0.6930475405331007 1.155574426629023 0.2478552733752876 1.0 0.6462261179969534 4 Q9NWH9,P35222,P31749 3 +Cell differentiation expanded index 0.6358143367206757 1.136788127758623 0.2556268676072135 1.0 0.64971828850167 2 Q15910 1 +Extracellular vesicles in the crosstalk of cardiac cells 0.6358143367206754 1.136788127758621 0.2556268676072144 1.0 0.64971828850167 2 Q96HC4 1 +Mammary gland development pathway involution stage 4 of 4 0.6336171381488546 1.1270411452622795 0.2597250851682371 1.0 0.652928473725992 2 P40763 1 +Pi3kaktmtor signaling pathway and therapeutic opportunities 0.6530577131370914 1.1198145618103197 0.262792792605389 1.0 0.652928473725992 5 Q15382,Q15118,P31749 3 +Apoptosisrelated network due to altered notch3 in ovarian cancer 0.4970119694609805 1.107717456149269 0.2679838581048797 1.0 0.652928473725992 14 P05067 1 +Cell migration and invasion through p75ntr 0.6153423150948436 1.095350538363771 0.2733630944475651 1.0 0.6565019197362785 6 Q9ULH0,P40763,P31751,P63000,P31749 5 +Transcription factors regulate mirnas related to cardiac hypertrophy 0.6766664633449033 1.090710648012416 0.2754002237619322 1.0 0.6587275210451158 4 P31751 1 +Neural crest cell migration in cancer 0.5225355738806372 1.088329702306538 0.2764495826025404 1.0 0.6587275210451158 10 Q99523,P31751 2 +Notch signaling 0.5569260175381067 1.0681760421146471 0.2854411096105453 1.0 0.6709232609980866 8 P78536 1 +Hostpathogen interaction of human coronaviruses apoptosis 0.6914835164835176 1.065582307340161 0.286612500613757 1.0 0.6709232609980866 3 Q07820,P31749 2 +Folatealcohol and cancer pathway hypotheses 0.6130184015380329 1.0360325272947295 0.3001869679105557 1.0 0.6756976030459004 2 Q99707 1 +Lncrnamediated mechanisms of therapeutic resistance 0.6121944520736 1.0324085618144156 0.3018807627536011 1.0 0.6770120047047672 2 P04637 1 +Notch signaling pathway 0.4708033656894322 1.0232105868710375 0.3062082883832502 1.0 0.6817045836269439 15 P78536,Q13573 2 +Complement and coagulation cascades 0.6790670007268627 1.017350766469477 0.3089865942216887 1.0 0.6829051538957613 3 P49257 1 +Glycosaminoglycan degradation 0.558034034139804 0.993142565228232 0.3206404832247058 1.0 0.6983721226566795 7 P16278,P15586,P54802 3 +Insulin signaling in adipocytes normal condition 0.6507282220390178 0.9886099876805864 0.3228539976871862 1.0 0.6983721226566795 4 P42345,P31751,O60343 3 +Insulin signaling in adipocytes diabetic condition 0.6507282220390178 0.9886099876805864 0.3228539976871862 1.0 0.6983721226566795 4 P42345,P31751,O60343 3 +Kennedy pathway from sphingolipids 0.5488689161765445 0.9525515301406396 0.3408173453742706 1.0 0.7075964629899392 7 P35790 1 +Burn wound healing 0.5268945582120804 0.9297653259204064 0.3524926028574788 1.0 0.7167349591435404 8 P08670 1 +Leptininsulin signaling overlap 0.6528391242309778 0.9163578106334322 0.3594792557672535 1.0 0.7237041122707083 3 P31749 1 +Interactions between loxl4 and oxidative stress pathway 0.6272657858137275 0.8972391892964451 0.3695912976580517 1.0 0.7278295381571471 4 Q16543 1 +Ciliary landscape 0.3244852221485244 0.8888905012507007 0.3740619308700492 1.0 0.7278295381571471 115 Q86VI3,Q9Y366,Q8IVV7,P06280,P16278,Q13868,O43805,P10619,P55081,O15078,O15173,P07197,Q15051,Q15555,P08670,Q9UNS2,Q14566,Q9BT78,Q9NQH7,P07196,A0AVF1 21 +P53 transcriptional gene network 0.5125626691318523 0.8643616093700711 0.3873892754185148 1.0 0.7397528563652268 8 P11166,P04066 2 +Nephrotic syndrome 0.4531098850952523 0.8618532920959656 0.3887682545482307 1.0 0.7397528563652268 14 P35579,P02545,O75844,Q14108 4 +Exrna mechanism of action and biogenesis 0.6368086189322681 0.8554117074066718 0.3923232645897809 1.0 0.7432210913036223 3 Q8WYQ5 1 +Tgfbeta signaling pathway 0.3610325145626986 0.8086096688645258 0.4187397014511291 1.0 0.7647641254047569 36 Q9NWH9,Q13464,P05067,Q13573 4 +Type i interferon induction and signaling during sarscov2 infection 0.6205032637394273 0.7942050065194202 0.4270760943951788 1.0 0.7753464808960091 3 Q7Z434 1 +Integrinmediated cell adhesion 0.3841688676589166 0.7741932451459419 0.438816522244597 1.0 0.7919469780153969 27 P17655,Q13464,O75116,P31751,O15484,Q14185 6 +Disruption of postsynaptic signaling by cnv 0.4903196622793134 0.7641537549233586 0.4447756214766312 1.0 0.7998291948775021 8 Q13555,Q14168 2 +Allograft rejection 0.4511347730029853 0.7503449957964906 0.4530469493405273 1.0 0.8033016430321233 11 P08670,P30511,P10321,P04439 4 +Pathways of nucleic acid metabolism and innate immune sensing 0.5290656014524043 0.7360126029793177 0.4617230279988304 1.0 0.8076563079685687 6 O00584 1 +Eicosanoid metabolism via lipooxygenases lox 0.5265578334616212 0.7259077084893897 0.4678953505949832 1.0 0.8076563079685687 6 Q8N8N7 1 +Amyotrophic lateral sclerosis als 0.4473265401243938 0.7123520288070758 0.4762468132404138 1.0 0.8156658776897459 10 P07197,P07196 2 +Sphingolipid pathway 0.4406355215900697 0.6979252039750188 0.4852239713394759 1.0 0.8244517053238565 11 Q16739,O95470,P04062,Q96G23,Q9NRA0 5 +Cholesterol metabolism with bloch and kandutschrussell pathways 0.3733228553540256 0.6978172095471825 0.4852915151321708 1.0 0.8244517053238565 27 Q16850,Q15392 2 +Dna mismatch repair 0.379775559556243 0.6819943100760968 0.4952425487445877 1.0 0.8345247368348025 21 Q9UQ84,P41440 2 +1q211 copy number variation syndrome 0.4373485049161615 0.6641456764866367 0.5065970781922013 1.0 0.8466416923212132 10 P54619,Q16625,Q9NPH0 3 +Sphingolipid metabolism in senescence 0.4296992604374143 0.6440292285670048 0.5195564806984778 1.0 0.8605953513491492 11 P16278,O15269,Q16739,P04062,Q96G23 5 +Somatroph axis gh and its relationship to dietary restriction and aging 0.5781186064737089 0.6400539234454627 0.5221375430361199 1.0 0.8608213547352247 3 P31749 1 +3q29 copy number variation syndrome 0.4224674759947752 0.6272644551330788 0.5304858989968839 1.0 0.8676897988727095 12 P02786,O75592,O95684 3 +Mitochondrial long chain fatty acid betaoxidation 0.4062401204957888 0.6071584248800497 0.5437457801513552 1.0 0.8751581158108883 14 O43772 1 +Pilocytic astrocytoma 0.5097500686624475 0.6018619839548287 0.5472660114013164 1.0 0.8782317302965905 2 P62993 1 +Airway smooth muscle cell contraction 0.5469033285345111 0.5977981510340086 0.5499746245463895 1.0 0.8782317302965905 4 O75116 1 +Focal adhesion 0.3280627004287318 0.5862507011894427 0.5577070547414482 1.0 0.885940894250738 41 P07942,P12814,Q13464,Q9NWH9,O43707,O75116,Q14185 7 +Eicosanoid metabolism via cyclooxygenases cox 0.4837211666002639 0.5585105484655498 0.57649580348152 1.0 0.8902846585410814 6 Q8N8N7 1 +Fibrin complement receptor 3 signaling pathway 0.5414315195999679 0.5145742663304183 0.6068505513869973 1.0 0.903766708818501 3 P31749 1 +Nocgmppkg mediated neuroprotection 0.4972571744555433 0.5134013337366192 0.607670612821924 1.0 0.903766708818501 5 Q13555 1 +Genes related to primary cilium development based on crispr 0.3530886518472968 0.5114121402481502 0.6090624957682964 1.0 0.903766708818501 20 Q9Y496,Q8WXW3,Q86SX3,O95684,Q9Y366,A0AVF1 6 +Arrhythmogenic right ventricular cardiomyopathy 0.3871636116825017 0.5082227182603042 0.6112971603319604 1.0 0.903766708818501 14 P12814,P35221,P50402,P17301,Q14126,P16615,O43707,P02545,P19022,P35222 10 +Il10 antiinflammatory signaling pathway 0.5173844192025179 0.4963744027025137 0.6196302813863825 1.0 0.908592479917532 4 P09601 1 +Transsulfuration and onecarbon metabolism 0.3473167614332012 0.4760840497408087 0.634014499887513 1.0 0.9149361479604148 19 O43865 1 +Reninangiotensinaldosterone system raas 0.5270957915543073 0.468153363399004 0.6396749202374266 1.0 0.91678245900295 3 Q13555 1 +G13 signaling pathway 0.3704894000291222 0.4622352159745796 0.643912651748495 1.0 0.91678245900295 15 O75116,Q7L576,Q13464 3 +Oxidative phosphorylation 0.315871140286959 0.4610627783353901 0.6447535654299434 1.0 0.91678245900295 38 P03886,P00846,O75787,P25705,O75964,O75380 6 +Ddx1 as a regulatory component of the drosha microprocessor 0.4777686246416758 0.4465652939230274 0.6551889589297599 1.0 0.92682855438214 5 Q92878 1 +Interactome of polycomb repressive complex 2 prc2 0.4109144610279972 0.4302820654347717 0.6669904715665647 1.0 0.9279018442828888 8 Q16576,Q9NYF8,O75530 3 +Vitamin b12 disorders 0.4940036143302177 0.4208372525036671 0.6738739271204075 1.0 0.9279018442828888 4 Q9NPF0 1 +Mirna biogenesis 0.4904433477453289 0.40976305515487 0.6819797700344878 1.0 0.9279018442828888 4 Q8WYQ5 1 +Praderwilli and angelman syndrome 0.4052142349797658 0.4084996181358842 0.6829069108381396 1.0 0.9279018442828888 8 O95714,Q7L576,Q96RK4 3 +Smc1smc3 role in dna damage cornelia de lange syndrome 0.4040866388870044 0.4042363790149204 0.6860389045435784 1.0 0.9279018442828888 8 Q9UQE7,Q92878,O60934,Q14683 4 +Circadian rhythm genes 0.2994225853671879 0.3731243793164253 0.7090558747252602 1.0 0.9506023814997994 43 O75116,P00813,P43490,P54802 4 +Ciliopathies 0.3263313688435545 0.3629297744905976 0.7166573441997992 1.0 0.956013196413028 25 Q15051,Q15555,O15078,Q8WXW3,Q96RK4,Q9Y366,Q9NQH7,Q13049 8 +Primary focal segmental glomerulosclerosis fsgs 0.3274444381913523 0.3614092760509715 0.7177935146838801 1.0 0.956013196413028 22 P35579,Q14108,P08670,P46939 4 +Mitochondrial complex i assembly model oxphos system 0.2993678949403701 0.3278889010654645 0.7429956659140871 1.0 0.9638193015784986 36 P03886,Q96CU9,O75380 3 +Gastric cancer network 2 0.3356234846343942 0.3237604805424688 0.7461193779255271 1.0 0.9638193015784986 16 P40938,Q03252 2 +Photodynamic therapyinduced nfkb survival signaling 0.4218621257896104 0.2992683328564875 0.7647353146950711 1.0 0.9638193015784986 2 O15111 1 +Canonical nfkb pathway 0.4218621257896104 0.2992683328564875 0.7647353146950711 1.0 0.9638193015784986 2 O15111 1 +Altered glycosylation of muc1 in tumor microenvironment 0.4218621257896104 0.2992683328564875 0.7647353146950711 1.0 0.9638193015784986 2 O15111 1 +Sting pathway in kawasakilike disease and covid19 0.4218621257896104 0.2992683328564875 0.7647353146950711 1.0 0.9638193015784986 2 O15111 1 +Fatty acid betaoxidation 0.3150919654944232 0.291710085808595 0.7705082971089956 1.0 0.9670988914331016 21 P23786,Q9UKU0,O43772 3 +Leukocyteintrinsic hippo pathway functions 0.3815317044513351 0.2883621930126205 0.7730695047200655 1.0 0.9673827864873484 7 Q13043,Q9Y448,Q16539,Q96GC9 4 +Purinergic signaling 0.4241341396371562 0.2822810783866628 0.77772799312958 1.0 0.9701719341698236 5 P09471,P63096,P04899,Q96RD7 4 +Wnt signaling 0.3163499842252664 0.2329378559636677 0.8158096620612456 1.0 0.9848741181679268 16 O75116,Q13555 2 +Metastatic brain tumor 0.4414835164835181 0.2327566858835176 0.815950348838254 1.0 0.9848741181679268 3 P60953,P04637 2 +Map3k1 role in promoting and blocking gonadal determination 0.4239288436827568 0.2281555041859995 0.819525351667292 1.0 0.9848741181679268 4 Q13464 1 +Supression of hmgb1 mediated inflammation by thbd 0.4390450754412024 0.2273002879332384 0.8201902492283719 1.0 0.9848741181679268 3 O15111 1 +Photodynamic therapyinduced hif1 survival signaling 0.3316798683805315 0.2224202813187727 0.823986724995666 1.0 0.9874890024506018 12 P53985 1 +Fragile x syndrome 0.2733110870676292 0.2004906002748182 0.8410969086542148 1.0 0.9935152640603166 46 Q14012,P53985,Q96F07,Q7L576,P05067 5 +Omega9 fatty acid synthesis 0.371185042617547 0.1990042538232621 0.8422594170777495 1.0 0.9935152640603166 6 O60488,O95864,P33121,O00767,O95573 5 +Neural crest cell migration during development 0.341971650484664 0.1974918175798498 0.8434426839759519 1.0 0.9935152640603166 8 P31751 1 +Chromosomal and microsatellite instability in colorectal cancer 0.2988413141972691 0.1829640732020564 0.85482620815527 1.0 0.9935152640603166 17 P48729,P20585,P31749,P31751,Q96KP1 5 +T cell receptor and costimulatory signaling 0.3435914442202485 0.18015742978885 0.857028977652823 1.0 0.9935152640603166 7 P48729,P31749 2 +Histone modifications 0.3251681216782178 0.1704292147153746 0.8646725982000478 1.0 0.9935152640603166 9 Q01105,O75530 2 +Wntbetacatenin signaling pathway in leukemia 0.3773057316366057 0.1686834879950148 0.866045607326017 1.0 0.9935152640603166 5 P48729,P31749 2 +Embryonic stem cell pluripotency pathways 0.3134941552570143 0.1583873289958341 0.874151597746647 1.0 0.9935152640603166 12 P31751,P61160,P35222,P31749 4 +Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence 0.3096395262600249 0.1478008248967242 0.8824999583159223 1.0 0.9935152640603166 13 P43490 1 +Mitochondrial complex iii assembly 0.3099018797098319 0.1463086748177959 0.8836777180372066 1.0 0.9935152640603166 11 P22695,Q9BRT2,Q6DKK2 3 +Regulation of apoptosis by parathyroid hormonerelated protein 0.3271837702089661 0.1410105078343717 0.8878616412388665 1.0 0.9935152640603166 7 Q07820,Q9BXK5 2 +Pi3kakt signaling pathway 0.2667002553758819 0.1394095439362194 0.8891265310356016 1.0 0.9935152640603166 44 P11802,P07942,Q13362,Q07820,P17301,Q9NWH9,P06756,P31751,Q16513,Q9UBI6,Q16543,Q14738,O15111,Q15382,P23588,P31749,P13807 17 +Ferroptosis 0.282004151648633 0.1381748577174759 0.8901022251114901 1.0 0.9935152640603166 28 Q9NZ45,Q9UKU0,P02786,P09601,Q9NZZ3,P45880,Q15758,P32929 8 +Hair follicle development organogenesis part 2 of 3 0.380014224376457 0.1195110700638687 0.9048704702510078 1.0 0.995704169499915 3 Q9BZE4 1 +Cardiac progenitor differentiation 0.3618300439978438 0.1104146008231459 0.9120805741466432 1.0 0.9988674151336666 4 Q6ZN17 1 +Hippo signaling regulation pathways 0.2835174534338243 0.0998855707646246 0.9204351719184936 1.0 1.0 16 Q13043,P54619,P13861,Q9NWH9,P35222 5 +Energy metabolism 0.289822003965682 0.0944391544261562 0.9247603140408852 1.0 1.0 14 Q13555 1 +Sarscov2 innate immunity evasion and cellspecific immune response 0.287175055948413 0.0863782849520701 0.931165708500714 1.0 1.0 10 Q7Z434,P42224,P35613 3 +Synaptic signaling pathways associated with autism spectrum disorder 0.2830033365561968 0.0764769403098178 0.9390396592047718 1.0 1.0 10 P31751,P54619,P31749 3 +Hostpathogen interaction of human coronaviruses interferon induction 0.2878210574721219 0.0732046702294365 0.941643250056136 1.0 1.0 8 O15111,Q7Z434,P42224 3 +Male infertility 0.2684681462486646 0.0664600303948697 0.947011578446979 1.0 1.0 23 P41440 1 +Mecp2 and associated rett syndrome 0.2656960376992643 0.0601593191765294 0.9520287455947594 1.0 1.0 21 P42345,Q9UQE7,Q03518,P35637,P52597,O75475,Q15910,Q00013,P62753,P31943,P31749 11 +Immune response to tuberculosis 0.3193901178174869 0.0563071151074841 0.9550971507932686 1.0 1.0 3 P42224 1 +Il18 signaling pathway 0.2516832886469304 0.0546067086322374 0.9564517940198995 1.0 1.0 61 Q9NQX7,Q9HC07,Q9UMR5,P61201,Q03252,Q8TCT8,Q969N2,Q9Y6M7,Q9UIG0 9 +Mirnas involvement in the immune response in sepsis 0.301539307311713 0.0538960287339584 0.9570180006802788 1.0 1.0 5 O15111,O14920,Q16539,Q15750 4 +Rett syndrome causing genes 0.272816476878407 0.0525392171960595 0.9580990476661976 1.0 1.0 15 P28370,Q8WXH0,P49770,Q9BZK7,Q14839,Q9HCS7,Q14683 7 +Nodlike receptor nlr signaling pathway 0.3014564440780556 0.0463434891538126 0.963036477193746 1.0 1.0 4 Q96RT1,O15111,O14920 3 +Complement system in neuronal development and plasticity 0.2693318905806566 0.0411041719578617 0.967212848674824 1.0 1.0 11 Q8N3R9 1 +Insulin signaling 0.2487309965052137 0.0408900964184118 0.9673835127588784 1.0 1.0 47 P11166,Q9Y496,P31751,O75955,P10586,P41440,P33176 7 +Rala downstream regulated genes 0.2861445633944739 0.0405146631872334 0.9676828171068588 1.0 1.0 5 P11233,Q96KP1 2 +Nrp1triggered signaling pathways in pancreatic cancer 0.2669672954743101 0.0362278330675177 0.9711006929732632 1.0 1.0 11 P31751,Q9NWH9 2 +Tlr4 signaling and tolerance 0.2719274127027815 0.0354373598686715 0.9717309945423158 1.0 1.0 6 Q15629,O43318,Q15750,O15111,O14920 5 +Ectoderm differentiation 0.2589103477698482 0.0321199077736317 0.9743764274928216 1.0 1.0 22 P16278,Q9P2E9,A1A4S6,P42356,P26583,P17480,P35222 7 +Neuroinflammation 0.2627160582453466 0.0279284562939137 0.9777192124511214 1.0 1.0 6 P42345,O15111,P00403 3 +Glucocorticoid receptor pathway 0.2553549720828076 0.0273930790772447 0.9781462182752232 1.0 1.0 7 Q86UP2 1 +Cohesin complex cornelia de lange syndrome 0.2517662209926196 0.0219754212870099 0.9824675617743128 1.0 1.0 18 Q9UQE7,P06493,Q13362,Q8N3U4,Q14738,Q29RF7,Q9NTI5 7 +Hematopoietic stem cell gene regulation by gabp alphabeta complex 0.2474212161518695 0.021865252362197 0.9825554427424664 1.0 1.0 4 Q07820 1 diff --git a/msigdb_wp/selections.json b/msigdb_wp/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..1455227e0b4384a753ff6a4fdc6ded6bb4e4190b --- /dev/null +++ b/msigdb_wp/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["15q112 copy number variation syndrome", "15q133 copy number variation syndrome", "16p112 distal deletion syndrome", "16p112 proximal deletion syndrome", "1q211 copy number variation syndrome", "22q112 copy number variation syndrome", "3q29 copy number variation syndrome", "4hydroxytamoxifen dexamethasone and retinoic acids regulation of p27 expression", "7oxoc and 7betahc pathways", "7q1123 copy number variation syndrome", "Ace inhibitor pathway", "Acetylcholine synthesis", "Acquired partial lipodystrophy barraquersimons syndrome", "Acute viral myocarditis", "Adipogenesis", "Aerobic glycolysis", "Aflatoxin b1 metabolism", "Agerage pathway", "Airway smooth muscle cell contraction", "Alanine and aspartate metabolism", "Allograft rejection", "Alpha 6 beta 4 signaling pathway", "Altered glycosylation of muc1 in tumor microenvironment", "Alternative pathway of fetal androgen synthesis", "Alzheimers disease", "Alzheimers disease and mirna effects", "Amino acid metabolism", "Amino acid metabolism pathway excerpt histidine catabolism extension", "Ampactivated protein kinase ampk signaling", "Amyotrophic lateral sclerosis als", "Androgen receptor signaling pathway", "Angiogenesis", "Angiopoietinlike protein 8 regulatory pathway", "Angiotensin ii receptor type 1 pathway", "Antiviral and antiinflammatory effects of nrf2 on sarscov2 pathway", "Apoptosis", "Apoptosis modulation and signaling", "Apoptosis modulation by hsp70", "Apoptosisrelated network due to altered notch3 in ovarian cancer", "Arachidonate epoxygenase epoxide hydrolase", "Arrhythmogenic right ventricular cardiomyopathy", "Aryl hydrocarbon receptor pathway wp2586", "Aryl hydrocarbon receptor pathway wp2873", "Arylamine metabolism", "Aspirin and mirnas", "Atm signaling in development and disease", "Atm signaling pathway", "Atr signaling", "Autophagy", "Autosomal recessive osteopetrosis pathways", "B cell receptor signaling pathway", "Base excision repair", "Bdnftrkb signaling", "Benzene metabolism", "Benzoapyrene metabolism", "Bile acids synthesis and enterohepatic circulation", "Biogenic amine synthesis", "Biomarkers for pyrimidine metabolism disorders", "Biomarkers for urea cycle disorders", "Biotin metabolism including iems", "Bladder cancer", "Bmp signaling in eyelid development", "Bmp2wnt4foxo1 pathway in primary endometrial stromal cell differentiation", "Brainderived neurotrophic factor bdnf signaling pathway", "Breast cancer pathway", "Burn wound healing", "Calcium regulation in cardiac cells", "Caloric restriction and aging", "Camkk2 pathway", "Cancer immunotherapy by ctla4 blockade", "Cancer immunotherapy by pd1 blockade", "Cannabinoid receptor signaling", "Canonical and noncanonical notch signaling", "Canonical and noncanonical tgfb signaling", "Canonical nfkb pathway", "Cardiac hypertrophic response", "Cardiac progenitor differentiation", "Ccl18 signaling pathway", "Cell cycle", "Cell differentiation expanded index", "Cell differentiation index", "Cell migration and invasion through p75ntr", "Cells and molecules involved in local acute inflammatory response", "Celltype dependent selectivity of cck2r signaling", "Cellular proteostasis", "Cerebral organic acidurias including diseases", "Chemokine signaling pathway", "Cholesterol biosynthesis pathway", "Cholesterol biosynthesis with skeletal dysplasias", "Cholesterol metabolism with bloch and kandutschrussell pathways", "Chromosomal and microsatellite instability in colorectal cancer", "Ciliary landscape", "Ciliopathies", "Circadian rhythm genes", "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism", "Clear cell renal cell carcinoma pathways", "Codeine and morphine metabolism", "Cohesin complex cornelia de lange syndrome", "Common pathways underlying drug addiction", "Complement and coagulation cascades", "Complement system", "Complement system in neuronal development and plasticity", "Congenital generalized lipodystrophy cgl", "Constitutive androstane receptor pathway", "Control of immune tolerance by vasoactive intestinal peptide", "Copper homeostasis", "Cori cycle", "Corticotropinreleasing hormone signaling pathway", "Cysteine and methionine catabolism", "Cytoplasmic ribosomal proteins", "Cytosine methylation", "Cytosolic dnasensing pathway", "Ddx1 as a regulatory component of the drosha microprocessor", "Degradation pathway of sphingolipids including diseases", "Deregulation of rab and rab effector genes in bladder cancer", "Development of pulmonary dendritic cells and macrophage subsets", "Development of ureteric collection system", "Disorders of folate metabolism and transport", "Disruption of postsynaptic signaling by cnv", "Dna damage response", "Dna damage response only atm dependent", "Dna irdamage and cellular response via atr", "Dna irdouble strand breaks and cellular response via atm", "Dna mismatch repair", "Dna repair pathways full network", "Dna replication", "Dopamine metabolism", "Dopaminergic neurogenesis", "Drug induction of bile acid pathway", "Dual hijack model of vif in hiv infection", "Ebola virus infection in host", "Ebsteinbarr virus lmp1 signaling", "Ectoderm differentiation", "Effect of progerin on genes involved in hutchinsongilford progeria syndrome", "Effects of nitric oxide", "Egfegfr signaling pathway", "Egfr tyrosine kinase inhibitor resistance", "Eicosanoid metabolism via cyclooxygenases cox", "Eicosanoid metabolism via cytochrome p450 monooxygenases pathway", "Eicosanoid metabolism via lipooxygenases lox", "Eicosanoid synthesis", "Electron transport chain oxphos system in mitochondria", "Embryonic stem cell pluripotency pathways", "Endochondral ossification", "Endochondral ossification with skeletal dysplasias", "Endoderm differentiation", "Endometrial cancer", "Endoplasmic reticulum stress response in coronavirus infection", "Endothelin pathways", "Energy metabolism", "Envelope proteins and their potential roles in edmd physiopathology", "Epithelial to mesenchymal transition in colorectal cancer", "Epo receptor signaling", "Erbb signaling pathway", "Erk pathway in huntingtons disease", "Estrogen metabolism", "Estrogen receptor pathway", "Estrogen signaling pathway", "Ethanol effects on histone modifications", "Ethanol metabolism production of ros by cyp2e1", "Eukaryotic transcription initiation", "Exerciseinduced circadian regulation", "Exrna mechanism of action and biogenesis", "Extracellular vesiclemediated signaling in recipient cells", "Extracellular vesicles in the crosstalk of cardiac cells", "Factors and pathways affecting insulinlike growth factor igf1akt signaling", "Familial hyperlipidemia type 1", "Familial hyperlipidemia type 2", "Familial hyperlipidemia type 3", "Familial hyperlipidemia type 4", "Familial hyperlipidemia type 5", "Familial partial lipodystrophy fpld", "Farnesoid x receptor pathway", "Fas ligand pathway and stress induction of heat shock proteins", "Fatty acid betaoxidation", "Fatty acid biosynthesis", "Fatty acid omegaoxidation", "Fatty acid transporters", "Fbxl10 enhancement of maperk signaling in diffuse large bcell lymphoma", "Ferroptosis", "Fgfr3 signaling in chondrocyte proliferation and terminal differentiation", "Fibrin complement receptor 3 signaling pathway", "Fluoroacetic acid toxicity", "Fluoropyrimidine activity", "Focal adhesion", "Focal adhesion pi3kaktmtorsignaling pathway", "Folate metabolism", "Folatealcohol and cancer pathway hypotheses", "Follicle stimulating hormone fsh signaling pathway", "Foxa2 pathway", "Foxp3 in covid19", "Fragile x syndrome", "Fto obesity variant mechanism", "G protein signaling pathways", "G1 to s cell cycle control", "G13 signaling pathway", "Gaba metabolism aka ghb", "Gaba receptor signaling", "Galanin receptor pathway", "Gammaglutamyl cycle for the biosynthesis and degradation of glutathione including diseases", "Ganglio sphingolipid metabolism", "Gastric cancer network 1", "Gastric cancer network 2", "Gastrin signaling pathway", "Gdnfret signaling axis", "Genes associated with the development of rheumatoid arthritis", "Genes controlling nephrogenesis", "Genes related to primary cilium development based on crispr", "Glial cell differentiation", "Glioblastoma signaling pathways", "Glucocorticoid receptor pathway", "Glucuronidation", "Glutathione metabolism", "Glycerolipids and glycerophospholipids", "Glycerophospholipid biosynthetic pathway", "Glycogen synthesis and degradation", "Glycolysis and gluconeogenesis", "Glycolysis in senescence", "Glycosaminoglycan degradation", "Glycosylation and related congenital defects", "Gpcrs class a rhodopsinlike", "Gpr143 in melanocytes and retinal pigment epithelium cells", "Gpr40 pathway", "H19 action rbe2f1 signaling and cdkbetacatenin activity", "Hair follicle development cytodifferentiation part 3 of 3", "Hair follicle development organogenesis part 2 of 3", "Head and neck squamous cell carcinoma", "Heart development", "Hedgehog signaling pathway wp4249", "Hedgehog signaling pathway wp47", "Hematopoietic stem cell gene regulation by gabp alphabeta complex", "Heme biosynthesis", "Hepatitis b infection", "Hepatitis c and hepatocellular carcinoma", "Hepatocyte growth factor receptor signaling", "Hereditary leiomyomatosis and renal cell carcinoma pathway", "Hif1a and pparg regulation of glycolysis", "Hijack of ubiquitination by sarscov2", "Hippo signaling regulation pathways", "Hippomerlin signaling dysregulation", "Hippoyap signaling pathway", "Histone modifications", "Homologous recombination", "Hostpathogen interaction of human coronaviruses apoptosis", "Hostpathogen interaction of human coronaviruses autophagy", "Hostpathogen interaction of human coronaviruses interferon induction", "Hostpathogen interaction of human coronaviruses mapk signaling", "Hypertrophy model", "Hypothesized pathways in pathogenesis of cardiovascular disease", "Id signaling pathway", "Il1 and megakaryocytes in obesity", "Il1 signaling pathway", "Il10 antiinflammatory signaling pathway", "Il17 signaling pathway", "Il18 signaling pathway", "Il2 signaling pathway", "Il3 signaling pathway", "Il4 signaling pathway", "Il5 signaling pathway", "Il6 signaling pathway", "Il7 signaling pathway", "Il9 signaling pathway", "Imatinib and chronic myeloid leukemia", "Immune response to tuberculosis", "Inclusion body myositis", "Inflammatory response pathway", "Influence of laminopathies on wnt signaling", "Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells", "Initiation of transcription and translation elongation at the hiv1 ltr", "Insulin signaling", "Insulin signaling in adipocytes diabetic condition", "Insulin signaling in adipocytes normal condition", "Integrated cancer pathway", "Integrinmediated cell adhesion", "Interactions between immune cells and micrornas in tumor microenvironment", "Interactions between loxl4 and oxidative stress pathway", "Interactions of natural killer cells in pancreatic cancer", "Interactome of polycomb repressive complex 2 prc2", "Interferon type i signaling pathways", "Interleukin1 il1 structural pathway", "Interleukin1 induced activation of nfkb", "Interleukin11 signaling pathway", "Intracellular trafficking proteins involved in cmt neuropathy", "Intraflagellar transport proteins binding to dynein", "Irinotecan pathway", "Iron metabolism in placenta", "Joubert syndrome", "Kallmann syndrome", "Kennedy pathway from sphingolipids", "Ketogenesis and ketolysis", "Ketone bodies synthesis and degradation", "Kininkallikrein pathway", "Kisspeptinkisspeptin receptor system in the ovary", "Kit receptor signaling pathway", "Krebs cycle disorders", "Kynurenine pathway and links to cell senescence", "Leptin and adiponectin", "Leptin signaling pathway", "Leptininsulin signaling overlap", "Leukocyteintrinsic hippo pathway functions", "Linoleic acid metabolism affected by coronavirus infection", "Lipid metabolism pathway", "Lipid particles composition", "Liver x receptor pathway", "Lncrna in canonical wnt signaling and colorectal cancer", "Lncrnamediated mechanisms of therapeutic resistance", "Ltf danger signal response pathway", "Lung fibrosis", "Male infertility", "Malignant pleural mesothelioma", "Mammalian disorder of sexual development", "Mammary gland development pathway embryonic development stage 1 of 4", "Mammary gland development pathway involution stage 4 of 4", "Mammary gland development pathway pregnancy and lactation stage 3 of 4", "Mammary gland development pathway puberty stage 2 of 4", "Map3k1 role in promoting and blocking gonadal determination", "Mapk and nfkb signaling pathways inhibited by yersinia yopj", "Mapk cascade", "Mapk pathway in congenital thyroid cancer", "Mapk signaling pathway", "Matrix metalloproteinases", "Mbdnf and probdnf regulation of gaba neurotransmission", "Measles virus infection", "Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms", "Mecp2 and associated rett syndrome", "Melanoma", "Melatonin metabolism and effects", "Mesodermal commitment pathway", "Met in type 1 papillary renal cell carcinoma", "Metabolic pathway of ldl hdl and tg including diseases", "Metabolic reprogramming in colon cancer", "Metabolism of alphalinolenic acid", "Metabolism of spingolipids in er and golgi apparatus", "Metapathway biotransformation phase i and ii", "Metastatic brain tumor", "Methionine de novo and salvage pathway", "Methionine metabolism leading to sulfur amino acids and related disorders", "Methylation pathways", "Mevalonate arm of cholesterol biosynthesis pathway", "Mevalonate pathway", "Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement", "Mfap5mediated ovarian cancer cell motility and invasiveness", "Microglia pathogen phagocytosis pathway", "Microrna for targeting cancer growth and vascularization in glioblastoma", "Microrna network associated with chronic lymphocytic leukemia", "Micrornas in cardiomyocyte hypertrophy", "Microtubule cytoskeleton regulation", "Mir124 predicted interactions with cell cycle and differentiation", "Mir517 relationship with arcn1 and usp1", "Mirna biogenesis", "Mirna regulation of dna damage response", "Mirna regulation of p53 pathway in prostate cancer", "Mirna regulation of prostate cancer signaling pathways", "Mirna targets in ecm and membrane receptors", "Mirnas involved in dna damage response", "Mirnas involvement in the immune response in sepsis", "Mitochondrial complex i assembly model oxphos system", "Mitochondrial complex ii assembly", "Mitochondrial complex iii assembly", "Mitochondrial complex iv assembly", "Mitochondrial fatty acid synthesis pathway", "Mitochondrial gene expression", "Mitochondrial immune response to sarscov2", "Mitochondrial long chain fatty acid betaoxidation", "Modulators of tcr signaling and t cell activation", "Molybdenum cofactor moco biosynthesis", "Monoamine transport", "Mrna processing", "Mrna protein and metabolite inducation pathway by cyclosporin a", "Mthfr deficiency", "Myd88 distinct inputoutput pathway", "Myometrial relaxation and contraction pathways", "Nad biosynthesis ii from tryptophan", "Nad biosynthetic pathways", "Nad metabolism", "Nad metabolism in oncogeneinduced senescence and mitochondrial dysfunctionassociated senescence", "Nad metabolism sirtuins and aging", "Nanomaterial induced apoptosis", "Nanoparticle triggered autophagic cell death", "Nanoparticle triggered regulated necrosis", "Nanoparticlemediated activation of receptor signaling", "Ncrnas involved in stat3 signaling in hepatocellular carcinoma", "Ncrnas involved in wnt signaling in hepatocellular carcinoma", "Neovascularisation processes", "Nephrogenesis", "Nephrotic syndrome", "Netrinunc5b signaling pathway", "Network map of sarscov2 signaling pathway", "Neural crest cell migration during development", "Neural crest cell migration in cancer", "Neural crest differentiation", "Neurodegeneration with brain iron accumulation nbia subtypes pathway", "Neuroinflammation", "Neuroinflammation and glutamatergic signaling", "Nicotine effect on dopaminergic neurons", "Nipbl role in dna damage cornelia de lange syndrome", "Nitric oxide metabolism in cystic fibrosis", "Nocgmppkg mediated neuroprotection", "Nodlike receptor nlr signaling pathway", "Nonalcoholic fatty liver disease", "Nongenomic actions of 125 dihydroxyvitamin d3", "Nonhomologous end joining", "Nonsmall cell lung cancer", "Notch signaling", "Notch signaling pathway", "Notch1 regulation of endothelial cell calcification", "Novel intracellular components of rigilike receptor rlr pathway", "Nrf2 pathway", "Nrf2are regulation", "Nrp1triggered signaling pathways in pancreatic cancer", "Nsp1 from sarscov2 inhibits translation initiation in the host cell", "Nuclear receptors in lipid metabolism and toxicity", "Nuclear receptors metapathway", "Nucleotide excision repair", "Nucleotide excision repair in xeroderma pigmentosum", "Nucleotide metabolism", "Nucleotidebinding oligomerization domain nod pathway", "Oligodendrocyte specification and differentiation leading to myelin components for cns", "Omega3 omega6 fatty acid synthesis", "Omega9 fatty acid synthesis", "Oncostatin m signaling pathway", "Onecarbon metabolism", "Onecarbon metabolism and related pathways", "Orexin receptor pathway", "Osteoblast differentiation and related diseases", "Osteoblast signaling", "Osteoclast signaling", "Osteopontin signaling", "Osx and mirnas in tooth development", "Ovarian infertility", "Overlap between signal transduction pathways contributing to lmna laminopathies", "Overview of interferonsmediated signaling pathway", "Overview of nanoparticle effects", "Oxidation by cytochrome p450", "Oxidative damage response", "Oxidative phosphorylation", "Oxidative stress response", "Oxysterols derived from cholesterol", "P38 mapk signaling pathway", "P53 transcriptional gene network", "Pancreatic adenocarcinoma pathway", "Parkinsons disease pathway", "Parkinubiquitin proteasomal system pathway", "Pathogenesis of sarscov2 mediated by nsp9nsp10 complex", "Pathogenic escherichia coli infection", "Pathways affected in adenoid cystic carcinoma", "Pathways of nucleic acid metabolism and innate immune sensing", "Pdgf pathway", "Pdgfrbeta pathway", "Pentose phosphate metabolism", "Pentose phosphate pathway in senescent cells", "Peroxiredoxin 2 induced ovarian failure", "Phase i biotransformations non p450", "Phosphodiesterases in neuronal function", "Phosphoinositides metabolism", "Photodynamic therapyinduced ap1 survival signaling", "Photodynamic therapyinduced hif1 survival signaling", "Photodynamic therapyinduced nfe2l2 nrf2 survival signaling", "Photodynamic therapyinduced nfkb survival signaling", "Photodynamic therapyinduced unfolded protein response", "Physicochemical features and toxicityassociated pathways", "Physiological and pathological hypertrophy of the heart", "Pi3kakt signaling pathway", "Pi3kaktmtor signaling pathway and therapeutic opportunities", "Pi3kaktmtor vitd3 signaling", "Pilocytic astrocytoma", "Pkcgamma calcium signaling pathway in ataxia", "Ppar signaling pathway", "Pparalpha pathway", "Praderwilli and angelman syndrome", "Pregnane x receptor pathway", "Preimplantation embryo", "Primary focal segmental glomerulosclerosis fsgs", "Prion disease pathway", "Progeriaassociated lipodystrophy", "Prolactin signaling pathway", "Prostaglandin and leukotriene metabolism in senescence", "Prostaglandin synthesis and regulation", "Proteasome degradation", "Proteoglycan biosynthesis", "Proximal tubule transport", "Ptf1a related regulatory pathway", "Purine metabolism", "Purine metabolism and related disorders", "Purinergic signaling", "Pyrimidine metabolism", "Pyrimidine metabolism and related diseases", "Quercetin and nfkb ap1 induced apoptosis", "Rac1pak1p38mmp2 pathway", "Rala downstream regulated genes", "Ranklrank signaling pathway", "Ras and bradykinin pathways in covid19", "Ras signaling", "Regucalcin in proximal tubule epithelial kidney cells", "Regulation of actin cytoskeleton", "Regulation of apoptosis by parathyroid hormonerelated protein", "Regulation of sister chromatid separation at the metaphaseanaphase transition", "Regulation of wnt bcatenin signaling by small molecule compounds", "Regulatory circuits of the stat3 signaling pathway", "Relationship between inflammation cox2 and egfr", "Reninangiotensinaldosterone system raas", "Resistin as a regulator of inflammation", "Retinoblastoma gene in cancer", "Rett syndrome causing genes", "Riboflavin and coq disorders", "Robo4 and vegf signaling pathways crosstalk", "S1p receptor signal transduction", "Sars coronavirus and innate immunity", "Sarscov2 altering angiogenesis via nrp1", "Sarscov2 and covid19 pathway", "Sarscov2 b117 variant antagonises innate immune activation", "Sarscov2 innate immunity evasion and cellspecific immune response", "Sarscov2 replication organelle formation", "Selenium micronutrient network", "Serine metabolism", "Serotonin and anxiety", "Serotonin and anxietyrelated events", "Serotonin htr1 group and fos pathway", "Serotonin receptor 2 and elksrfgata4 signaling", "Serotonin receptor 467 and nr3c signaling", "Serotonin transporter activity", "Signal transduction through il1r", "Sleep regulation", "Small cell lung cancer", "Smc1smc3 role in dna damage cornelia de lange syndrome", "Somatroph axis gh and its relationship to dietary restriction and aging", "Sphingolipid metabolism in senescence", "Sphingolipid metabolism integrated pathway", "Sphingolipid metabolism overview", "Sphingolipid pathway", "Spinal cord injury", "Splicing factor nova regulated synaptic proteins", "Srebf and mir33 in cholesterol and lipid homeostasis", "Statin inhibition of cholesterol production", "Steroid biosynthesis", "Sterol regulatory elementbinding proteins srebp signaling", "Sting pathway in kawasakilike disease and covid19", "Striated muscle contraction pathway", "Sudden infant death syndrome sids susceptibility pathways", "Sulfation biotransformation reaction", "Supression of hmgb1 mediated inflammation by thbd", "Synaptic signaling pathways associated with autism spectrum disorder", "Synaptic vesicle pathway", "T cell receptor and costimulatory signaling", "Tamoxifen metabolism", "Target of rapamycin tor signaling", "Tca cycle aka krebs or citric acid cycle", "Tca cycle and deficiency of pyruvate dehydrogenase complex pdhc", "Tca cycle in senescence", "Tca cycle nutrient use and invasiveness of ovarian cancer", "Tcell activation sarscov2", "Tcell antigen receptor tcr pathway during staphylococcus aureus infection", "Tcell receptor tcr signaling pathway", "Tgfbeta receptor signaling", "Tgfbeta receptor signaling in skeletal dysplasias", "Tgfbeta signaling in thyroid cells for epithelialmesenchymal transition", "Tgfbeta signaling pathway", "Thermogenesis", "Thiamine metabolic pathways", "Thymic stromal lymphopoietin tslp signaling pathway", "Thyroid hormones production and peripheral downstream signaling effects", "Thyroid stimulating hormone tsh signaling pathway", "Tlr4 signaling and tolerance", "Tnfalpha signaling pathway", "Tnfrelated weak inducer of apoptosis tweak signaling pathway", "Tolllike receptor signaling pathway", "Tolllike receptor signaling related to myd88", "Tp53 network", "Transcription cofactors ski and skil protein partners", "Transcription factor regulation in adipogenesis", "Transcription factors regulate mirnas related to cardiac hypertrophy", "Transcriptional activation by nrf2 in response to phytochemicals", "Translation factors", "Translation inhibitors in chronically activated pdgfra cells", "Transsulfuration and onecarbon metabolism", "Transsulfuration pathway", "Triacylglyceride synthesis", "Tryptophan catabolism leading to nad production", "Tryptophan metabolism", "Tumor suppressor activity of smarcb1", "Type 2 papillary renal cell carcinoma", "Type i collagen synthesis in the context of osteogenesis imperfecta", "Type i interferon induction and signaling during sarscov2 infection", "Type ii diabetes mellitus", "Type ii interferon signaling ifng", "Type iii interferon signaling", "Tyrobp causal network in microglia", "Ultraconserved region 339 modulation of tumor suppressor micrornas in cancer", "Unfolded protein response", "Urea cycle and associated pathways", "Urea cycle and metabolism of amino groups", "Urea cycle and related diseases", "Valproic acid pathway", "Vasopressinregulated water reabsorption", "Vegfavegfr2 signaling pathway", "Vitamin a and carotenoid metabolism", "Vitamin b12 disorders", "Vitamin b12 metabolism", "Vitamin b6dependent and responsive disorders", "Vitamin d in inflammatory diseases", "Vitamin d metabolism", "Vitamin d receptor pathway", "Vitamin dsensitive calcium signaling in depression", "White fat cell differentiation", "Wnt signaling", "Wnt signaling in kidney disease", "Wnt signaling pathway", "Wnt signaling pathway and pluripotency", "Wntbetacatenin signaling pathway in leukemia", "Zinc homeostasis"], "available_proteins": ["AAMP", "AARS", "AASS", "ABAT", "ABCB1", "ABCC1", "ABCC4", "ABCD3", "ABCF1", "ABCF2", "ABHD11", "ABI1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAR", "ADH5", "ADI1", "ADK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "AMFR", "AMOT", "ANAPC1", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANK3", "ANLN", "ANP32A", "ANXA1", "ANXA2", "ANXA3", "ANXA6", "AP1G1", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "APBB1", "APEX1", "APLP2", "APMAP", "APOC1", "APP", "APRT", "ARCN1", "ARF4", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGAP10", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARIH2", "ARL2", "ARL3", "ARL6", "ARL8B", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARVCF", "ASAH1", "ASCC1", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATG3", "ATG5", "ATG7", "ATIC", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0D1", "ATP6V1A", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "BAG2", "BAG3", "BAG4", "BAIAP2", "BAK1", "BANF1", "BAZ1A", "BAZ1B", "BBS4", "BCAS3", "BCAT2", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BECN1", "BLM", "BLVRA", "BPTF", "BRCA1", "BRD4", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "C1QBP", "CAB39", "CACYBP", "CAD", "CADM1", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CANT1", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPZB", "CARM1", "CASK", "CBR1", "CBX1", "CBX3", "CBX5", "CC2D1A", "CCAR2", "CCDC124", "CCDC6", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC7", "CDC73", "CDH2", "CDIPT", "CDK1", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CEP170", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAMP1", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHKA", "CHMP5", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHUK", "CIP2A", "CISD1", "CKB", "CLASP1", "CLASP2", "CLCN7", "CLIC1", "CLPTM1L", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMPK1", "CNOT1", "CNOT9", "CNP", "COA3", "COASY", "COLEC12", "COLGALT1", "COMT", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ8A", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPT1A", "CPT2", "CRK", "CRKL", "CRTAP", "CS", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTTN", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CXADR", "CYB5B", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAGLB", "DARS", "DAXX", "DBNL", "DCAF1", "DCAF7", "DCK", "DCP1A", "DCTN1", "DCTN2", "DCTN4", "DCTPP1", "DDB1", "DDOST", "DDX1", "DDX17", "DDX20", "DDX21", "DDX3X", "DDX5", "DDX52", "DDX56", "DEK", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DLAT", "DLD", "DLGAP5", "DLST", "DMAC2", "DNAAF5", "DNAJA1", "DNAJB1", "DNAJB11", "DNAJC3", "DNAJC7", "DNAJC8", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK1", "DPF2", "DPM1", "DPP9", "DPYSL2", "DSC3", "DSG2", "DSP", "DSTN", "DTYMK", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECSIT", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFTUD2", "EHBP1", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF4A1", "EIF4A2", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAVL1", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP3", "ELP4", "EMD", "EML4", "ENAH", "ENDOG", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERBIN", "ERCC2", "ERCC3", "ESD", "ESS2", "ETF1", "ETFA", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC2", "EXOSC4", "EXOSC7", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAH", "FAM120A", "FAM91A1", "FANCG", "FANCI", "FARSB", "FASN", "FAU", "FDFT1", "FDPS", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIS1", "FKBP10", "FKBP15", "FKBP1A", "FKBP2", "FKBP4", "FKBP5", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMR1", "FNTA", "FOXRED1", "FSCN1", "FTO", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G6PD", "GABARAPL2", "GABPA", "GAL", "GALNS", "GALNT1", "GAMT", "GAPDH", "GART", "GBA", "GCC1", "GCC2", "GCDH", "GCLC", "GCLM", "GDI1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GID4", "GID8", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLRX", "GLS", "GM2A", "GMPPB", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPAT", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPS1", "GPT2", "GRB2", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTPBP4", "GUSB", "GYG1", "GYS1", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HADH", "HADHA", "HADHB", "HAT1", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HEBP1", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HYOU1", "IARS", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP3", "IKBKB", "ILF2", "ILK", "IMP3", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INPP4A", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRS4", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "IVD", "JUP", "KAT7", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIDINS220", "KIF20B", "KIF22", "KIF23", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KLC1", "KLC2", "KNSTRN", "KPNA1", "KPNB1", "KTN1", "L2HGDH", "LAMB1", "LAMC1", "LARP1", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMNA", "LMNB1", "LMNB2", "LONP2", "LPGAT1", "LRPPRC", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM2", "LSM7", "LSS", "LTA4H", "LZTFL1", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGT1", "MANF", "MAP1B", "MAP2K1", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC2", "MARCKS", "MARK2", "MARS", "MARS2", "MAT2A", "MAT2B", "MAU2", "MAVS", "MBD3", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCU", "MDC1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MEPCE", "MFAP1", "MFN2", "MGST1", "MGST2", "MGST3", "MIA3", "MIF", "MKI67", "MMAB", "MOCS1", "MOGS", "MORF4L1", "MOV10", "MPC2", "MPDU1", "MPG", "MPI", "MPP1", "MPP2", "MPP5", "MPST", "MRE11", "MRI1", "MRPL19", "MRPL40", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTDH", "MTERF3", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTOR", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYEF2", "MYH10", "MYH9", "MYL6", "MYO1C", "MYO6", "NAA15", "NAA16", "NAA40", "NAA50", "NADSYN1", "NAE1", "NAGLU", "NAMPT", "NAP1L1", "NAPA", "NARS", "NAT10", "NBN", "NCAPG", "NCAPG2", "NCBP1", "NCDN", "NCK1", "NCKAP1", "NCL", "NCSTN", "ND1", "ND5", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NFATC2IP", "NIPBL", "NKRF", "NME1", "NME2", "NONO", "NOP2", "NOTCH2", "NPC1", "NPC2", "NRP1", "NSD1", "NSDHL", "NSF", "NT5C3A", "NTHL1", "NUBPL", "NUDC", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP214", "NUP62", "NUP88", "NUP98", "NXF1", "OAT", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "ORC2", "ORC3", "ORC5", "OSBPL3", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAICS", "PAK2", "PAK4", "PANX1", "PAPOLA", "PAPSS1", "PARK7", "PARN", "PARP1", "PARP2", "PARVA", "PAX6", "PBK", "PBRM1", "PC", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCM1", "PCNA", "PDCD4", "PDCD6", "PDCD6IP", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA6", "PDK1", "PDLIM5", "PDLIM7", "PDP1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PEBP1", "PECR", "PELO", "PET100", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGRMC2", "PHB", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PIAS2", "PIBF1", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PISD", "PKM", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PMPCA", "PMVK", "PNKP", "PNP", "PNPO", "PNPT1", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "PON2", "POR", "PPAT", "PPIB", "PPID", "PPIF", "PPM1G", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPT2", "PRCC", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PRPF3", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRRC2C", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSPC1", "PTBP1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPRF", "PTRH2", "PURA", "PUS1", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QKI", "RAB10", "RAB11B", "RAB13", "RAB14", "RAB21", "RAB23", "RAB2A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABGAP1", "RABGEF1", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RALA", "RAN", "RANBP1", "RANBP9", "RANGAP1", "RAPGEF2", "RARS", "RBBP4", "RBBP7", "RBM14", "RBM17", "RBM39", "RBM4", "RBM5", "RBMX", "RCC1", "RCN1", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RHBDD2", "RHEB", "RHOG", "RIF1", "RIPK1", "RMI1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF40", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPRD1B", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RTCB", "RTF1", "RTN3", "RTN4", "RUVBL1", "S100A10", "S100A11", "SACM1L", "SAFB", "SAMHD1", "SAP18", "SAP30", "SAR1A", "SAR1B", "SARS", "SC5D", "SCAF11", "SCAMP2", "SCARB1", "SCARB2", "SCD", "SCO1", "SCO2", "SCP2", "SCRIB", "SDCBP", "SDHA", "SDHB", "SEC13", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEL1L", "SELENBP1", "SEPT11", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SFPQ", "SFSWAP", "SGPL1", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SKP1", "SKP2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A25", "SLC25A4", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLIT2", "SLTM", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMS", "SMYD3", "SNAP29", "SND1", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SOAT1", "SOD2", "SORT1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPTAN1", "SPTBN1", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRM", "SRP54", "SRPK1", "SRRM1", "SRSF1", "SRSF10", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSNA1", "SSR3", "SSR4", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STIP1", "STK4", "STMN1", "STOM", "STRAP", "STRN", "STUB1", "STX4", "STXBP2", "STXBP3", "STXBP4", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUN1", "SUPT5H", "SUZ12", "SYNE2", "TAB1", "TALDO1", "TAP1", "TARDBP", "TBC1D4", "TBCA", "TBL1XR1", "TBL2", "TCP1", "TCTN3", "TECR", "TEDC1", "TELO2", "TERF2IP", "TFAM", "TFB1M", "TFCP2", "TFRC", "THRAP3", "TIGAR", "TIMELESS", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TMED10", "TMEM126B", "TMEM165", "TMEM38B", "TMEM43", "TMEM70", "TMOD1", "TMOD3", "TMPO", "TMPO", "TNKS1BP1", "TNPO1", "TOLLIP", "TOMM40", "TOMM70", "TOP1", "TOP2A", "TOR1AIP1", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPX2", "TRA2A", "TRA2B", "TRAM1", "TRAP1", "TRAPPC11", "TRIM25", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRIP4", "TRMT2A", "TRRAP", "TSG101", "TSPO", "TSPYL1", "TTC19", "TTC26", "TTF2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUBGCP3", "TUFM", "TWISTNB", "TXNDC15", "TXNDC5", "TXNRD1", "TYMS", "U2AF1", "U2AF2", "UBA1", "UBA3", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2L3", "UBE2N", "UBE2V1", "UBIAD1", "UBR5", "UBTF", "UCHL5", "UCK2", "UFD1", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UNG", "UPF1", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP1", "USP10", "USP5", "USP7", "USP8", "USP9X", "UTRN", "VANGL1", "VAPA", "VAPB", "VARS1", "VBP1", "VCL", "VDAC1", "VDAC2", "VDAC3", "VIM", "VMP1", "VPS16", "VPS18", "VPS28", "VPS33A", "VPS36", "VPS37B", "VPS4A", "WAPL", "WARS", "WASF2", "WDHD1", "WDR1", "WDR34", "WDR5", "WDR73", "WDR74", "WFS1", "WNK1", "WRN", "XAB2", "XPNPEP3", "XPO1", "XPO5", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZC3H15", "ZFR", "ZFYVE16", "ZMPSTE24", "ZNF281", "ZNF318", "ZYX"], "leading_proteins": ["ACP6", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTN1", "ACTN4", "ACTR2", "ADA", "ADAM17", "ADK", "AGPS", "AHCYL1", "AKT1", "AKT2", "ALDH1A2", "APLP2", "APP", "ARHGAP10", "ARHGEF1", "ASNA1", "ATP2A2", "ATP5A1", "ATP5L", "ATP6", "ATP6AP2", "B3GALT6", "B4GALT1", "BAIAP2", "BAZ1B", "BBS4", "BCL2L13", "BCLAF1", "BECN1", "BSG", "CADM1", "CAMK1", "CAMK2G", "CANT1", "CAPN2", "CAPN5", "CD320", "CDC20", "CDC37", "CDC42", "CDH2", "CDK1", "CDK4", "CEP290", "CEPT1", "CERS1", "CERS2", "CHD4", "CHKA", "CHMP5", "CHST14", "CHUK", "CISD1", "COPS2", "COPS3", "COPS4", "COX2", "CPT2", "CSNK1A1", "CSRP2", "CTH", "CTNNA1", "CTNNB1", "CTSA", "CYFIP1", "CYFIP2", "CYP51A1", "DGCR8", "DHCR24", "DHCR7", "DOCK1", "DSG2", "ECE1", "EED", "EIF2B2", "EIF4B", "EMD", "EPHX1", 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b/opencell_localization/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +mitochondria 1 10 2.327737409194809 0.0199260514320995 4.441747572815534 10.567961165048544 1.1937677940164793 0.2159787381789819 2.254231157409949 0.7391563798220593 1.4011905974754153 0.2980089661914649 1.0 0.0595353304203936 0.0065261066260236 0.0379575415698398 0.0227185425065092 +membrane 22 90 2.115819429719065 0.0343601679560425 16.393203883495147 79.79611650485437 0.0361236836555693 0.7658828087328957 7.7114687271171185 8.840670825600329 0.5889166851077953 0.2834223929246602 1.0 0.2042324090251818 0.0895474274455174 0.00125083348107 1.6722376706818463e-05 +vesicles 50 200 2.114373563837708 0.0344833737404701 42.101941747572816 169.6626213592233 0.6789633151163722 0.6006686966705359 14.133870910307197 18.74575061031192 1.1351302778834993 0.3922666308151308 1.0 0.0053152378990195 0.0054633777773489 3.035163569035868e-05 2.532277653914674e-07 diff --git a/opencell_localization/metrics.json b/opencell_localization/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..dec673513b9ab58b4a3f04332b7871df8f6149d5 --- /dev/null +++ b/opencell_localization/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 17, + "title": "Average number of proteins per term", + "value": 105.47058823529412 +} \ No newline at end of file diff --git a/opencell_localization/paths.json b/opencell_localization/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..767081e3bf173d0cafd7521d35b8256db354b61c --- /dev/null +++ b/opencell_localization/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/opencell_localization/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/opencell_localization/result.tsv b/opencell_localization/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..e5d067119ef4e557688b5dc3a36ca3a4abb41567 --- /dev/null +++ b/opencell_localization/result.tsv @@ -0,0 +1,10 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +mitochondria 0.7745780712712114 2.327737409194809 0.0199260514320995 0.2897677796542989 0.1465543383969982 10 P21796 1 +membrane 0.4354694179935424 2.115819429719065 0.0343601679560425 0.4481031424695239 0.1465543383969982 90 P84095,Q96N67,Q01650,O00291,Q9Y5S2,Q9UQB8,P46939,P35579,P02786,P53985,P30825,P12814,O60499,O15127,Q9NZM3,Q96RU3,Q13464,O43707,P41440,P08670,Q9Y5X1,P31751 22 +vesicles 0.3985630909488541 2.114373563837708 0.0344833737404701 0.4492990002490554 0.1465543383969982 200 Q92538,Q8WUH2,Q9HD42,Q6NT16,Q8IZA0,Q8IXU6,Q96PE3,Q01650,O60476,O14976,O00291,Q5VW38,Q8IZD4,Q9Y5X2,P11166,Q06481,P02786,P53985,Q15392,Q07960,O75787,Q96L92,Q9Y6K0,P30825,Q14457,O60499,O15127,Q9NZM3,O15173,P55735,Q8IY95,Q9Y678,Q93050,O43752,P61020,P04439,P51798,O15400,O60749,P41440,Q567U6,Q969M3,P31749,Q8NBN3,Q15075,Q15437,Q7Z4G1,P31751,O95219,O60826 50 +golgi 0.4258333149735369 1.9273565715722156 0.0539352079029686 0.6103676858055332 0.1833797068700935 69 O15127,Q08379,Q9Y487,P55735,Q8IZA0,Q8IXU6,Q07960,O75787,P35606,Q15437,O14976,Q5VW38,Q969M3,Q8NBN3 14 +cytoskeleton 0.410600140265865 1.1967598775771726 0.2314001609606735 0.9885999983018852 0.6556337893885749 34 P35579,P12814,P35580,P08670,P52732 5 +cell_contact 0.3976610615205572 1.0905583741245075 0.2754672542540897 0.9958218280011176 0.6689919031885035 34 Q9NZM3,Q96RU3,Q13464,Q96N67,Q9UQB8 5 +nuclear_membrane 0.3119101635064494 0.3880634401145713 0.6979690865366284 0.9999999985516492 0.858688314331677 33 P20700,P55735,P12270,P57740,Q9Y2U8,Q9C0E2,P02545,Q14739,P42166,P49792 10 +nucleolus_fc_dfc 0.254733027003367 0.0114427981991827 0.9908701672247028 1.0 1.0 26 Q15233,Q8IXT5,P17480,P55769 4 +er 0.254547987403015 0.0031738544459584 0.9974676347909026 1.0 1.0 100 Q8N4V1,Q16850,O60499,O15173,Q9Y487,P84095,Q07960,Q15392,Q07065,Q9Y6K0,P04843,Q969M3 12 diff --git a/opencell_localization/selections.json b/opencell_localization/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..f0b3c25be9264a59f6f7ca209f53c2b3b9536e42 --- /dev/null +++ b/opencell_localization/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["big_aggregates", "cell_contact", "centrosome", "chromatin", "cytoplasmic", "cytoskeleton", "er", "focal_adhesions", "golgi", "membrane", "mitochondria", "nuclear_membrane", "nuclear_punctae", "nucleolus_fc_dfc", "nucleolus_gc", "nucleoplasm", "vesicles"], "available_proteins": ["AAMP", "AATF", "ABCE1", "ABR", "ACLY", "ACTN1", "ACTN4", "ACTR2", "AGAP3", 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b/panther_protein_class/df_merge.tsv @@ -0,0 +1,8 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +transporter 15 66 3.0657334659068307 0.0021713678276242 16.281553398058254 57.34708737864078 1.7781248355514696 0.2510912048406951 6.627271511266295 3.5084386843827997 1.4364723564792363 0.3433005081320681 1.0 0.0021714502363067 0.0050877311387192 0.000517121164567 0.0001639539701712 +serine protease 7 19 2.3768624652921644 0.0174605971147387 5.662621359223301 17.516990291262136 1.1445634795625386 0.1820139001244477 2.0809494011218104 1.6626107291843584 1.568325484830445 0.2384821649427795 0.0516364610574793 0.0221752921749746 0.0112094197528849 0.0063027604866002 0.0022946198906289 +metalloprotease 8 27 2.3561426244973567 0.0184658262602459 8.58495145631068 26.398058252427184 1.4262736372921438 0.246779453311036 3.321022586051017 1.6463540525991265 1.1083706824215755 0.2918245458017476 1.0 0.0265864003984115 0.0145863017156454 0.0094868932073139 0.0010655904765625 +transmembrane signal receptor 5 8 2.330772204753784 0.0197653745013302 3.266990291262136 7.169902912621359 1.6693846681257831 0.1085289610325799 1.5770125590990791 1.7927217985188668 1.0928815816574815 0.16461969248918 0.094940205790926 0.0695355637495909 0.0571659879107951 0.1818956974368412 0.2901381975294353 +acyltransferase 4 20 2.091306540865336 0.0365005938637601 5.550970873786408 17.609223300970875 0.8395368249042097 0.3495065414698917 3.0409541216574527 2.8086572783837886 1.152491475155923 0.3107783941454108 0.0444114041010999 0.0165768393094286 0.0073262411490521 0.0032221742646108 0.0516637732040453 +phospholipase 2 7 2.0703834545586264 0.0384164499975403 2.0266990291262137 7.405339805825243 0.812358854363279 0.2972812642592555 1.2910317153343125 1.5290934655146406 1.1524828353366978 0.2736190413418742 1.0 1.0 0.0028129637769054 0.0348798008289802 0.1773693871336699 +oxygenase 1 7 1.9782742814623395 0.0478977728352991 3.138349514563106 6.771844660194175 1.5409868347565758 0.1477866581414416 1.2914149665013366 1.041089559555361 1.2379399582807478 0.2357869798067575 1.0 0.1071891284628969 0.0215793786244467 0.1131762501747812 0.3271248077551284 diff --git a/panther_protein_class/metrics.json b/panther_protein_class/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..db76ea8f97fe5cceadeecbeeda01b9115a13aafe --- /dev/null +++ b/panther_protein_class/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 162, + "title": "Average number of proteins per term", + "value": 15.08641975308642 +} \ No newline at end of file diff --git a/panther_protein_class/paths.json b/panther_protein_class/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..3bf2f3d84581d86482936821306ae06f686b2226 --- /dev/null +++ b/panther_protein_class/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/panther_protein_class/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/panther_protein_class/result.tsv b/panther_protein_class/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..732d2bbc9c566e409228a5deed33701dcc1fb9c5 --- /dev/null +++ b/panther_protein_class/result.tsv @@ -0,0 +1,48 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +transporter 0.5451110843219305 3.0657334659068307 0.0021713678276242 0.2968211738042737 0.0319783261886485 66 Q9NR77,Q15012,P55735,P53985,O43772,Q9HD45,Q01650,Q9C0E2,Q567V2,P39210,O43681,Q8N1F7,P41440,Q9NUN5,Q99805 15 +galactosidase 0.9563306783850588 2.529495901616648 0.0114226508042212 0.844501507258852 0.0973931279096757 2 P06280 1 +serine protease 0.6465312405941414 2.3768624652921644 0.0174605971147387 0.9423636984563014 0.1346960348851278 19 Q9H3G5,Q9HB40,P42785,Q4J6C6,Q16740,O14773,P10619 7 +metalloprotease 0.6090516498015713 2.3561426244973567 0.0184658262602459 0.9511708874926738 0.1359756297345384 27 P22695,P52888,Q9UIQ6,Q9NZ08,P42892,Q9NQH7,O75844,P55786 8 +transmembrane signal receptor 0.8371043326347164 2.330772204753784 0.0197653745013302 0.9606027080045332 0.1392169856180649 8 Q99720,O15173,O75787,Q8WUJ1,Q9UMX5 5 +acyltransferase 0.5968409177803342 2.091306540865336 0.0365005938637601 0.9975793326519978 0.2044110458137712 20 P23786,Q8NCC3,Q9HCL2,Q9BWD1 4 +phospholipase 0.8029721131933231 2.0703834545586264 0.0384164499975403 0.998246531064968 0.2074488299867178 7 Q8NHP8,Q8N2A8 2 +voltage-gated ion channel 0.9462990317780916 2.055796231707351 0.0398021614140833 0.9986118471361206 0.2079983919058548 3 P21796 1 +G-protein coupled receptor 0.9173688725345496 2.0357463845287636 0.0417758287539675 0.9990053421266752 0.2108971873398757 4 Q9NPR9,Q5VW38 2 +oxygenase 0.7812940607575125 1.9782742814623393 0.0478977728352991 0.9996478399132314 0.2220614092695385 7 P30519 1 +membrane trafficking regulatory protein 0.5660247875732716 1.9309398865558016 0.0534904868303238 0.9998644038687564 0.2407071907364574 22 Q8WTV0,Q96EA4,Q14108 3 +protease 0.4711210235982453 1.8051904558401537 0.0710448839335555 0.9999934664923787 0.279196649809958 40 P28070,P28074,Q9UNS2,P20618,O75976,P49721,P28072,P78536,Q99436,P60900 10 +lyase 0.5779589427586332 1.733982058305363 0.0829212666437722 0.9999991874074432 0.2864951190141034 16 P22830 1 +protease inhibitor 0.6203712409909724 1.6656541194102013 0.0957823251966374 0.9999999175435376 0.3021795057912069 12 P05067,Q06481 2 +actin binding motor protein 0.7077458511972526 1.6595953185954218 0.0969958907477948 0.999999933666072 0.3021795057912069 7 P67936,P09493 2 +major histocompatibility complex protein 0.801596951340724 1.586302900798722 0.1126706146014386 0.9999999961118056 0.3192639864203692 4 P30511,P10321 2 +secondary carrier transporter 0.5116300837171678 1.535735399102515 0.1246032893597721 0.999999999566294 0.3364288812713848 19 P55011,Q9UBX3,Q96H78,Q6NT16,Q9BQT8,Q8TB61,Q9Y666,Q8N1S5,Q9Y6M7 9 +hydrolase 0.5021741130307121 1.5253950146997453 0.1271606014632103 0.9999999997300004 0.3377052038859027 23 O60502,O43865,P07099 3 +guanyl-nucleotide exchange factor 0.5920208836938724 1.477072101040181 0.1396563111218838 0.9999999999738868 0.3573274827365841 11 Q92538,Q96N67,Q9Y4G8,Q9HCU5,Q92888,Q14185 6 +ATP synthase 0.4963681058851899 1.4714612746240918 0.1411664129329715 0.9999999999803546 0.3573274827365841 22 Q9Y487,P00846,P25705,Q93050,O75964 5 +ATP-binding cassette (ABC) transporter 0.5672655289659867 1.38698122314878 0.1654474885170918 0.9999999999998114 0.4000372110413264 12 O75027 1 +mitochondrial carrier protein 0.593172153746047 1.3360208742704562 0.1815424505448861 0.999999999999992 0.4201410998324508 9 Q9BSK2,Q86VD7,Q70HW3,Q9HC21 4 +calmodulin-related 0.5019951545834748 1.2048173552411232 0.2282738185739767 1.0 0.4801964274292735 15 Q9BRK5,Q02818,Q14257,Q8IYU8,P80303 5 +extracellular matrix protein 0.6393105008915431 1.1972588265714974 0.2312056872807613 1.0 0.4801964274292735 6 P07942,P55081 2 +membrane traffic protein 0.3540920626286006 1.141960752046305 0.2534703340854285 1.0 0.4888356443076121 85 Q9HD42,Q9BQT9,Q8N2H4,O43493,Q92734,O14976,Q13432,P11717,O60313,Q5THJ4,P20645,Q9UPT5,Q08379,P42566,Q8IUD2,A6NIH7,P49257,Q96ED9,Q12768,Q9NZM3,Q9NZZ3,Q99747,Q9UQ16,Q9H223,O60763,Q86VS8,Q96PC5,Q99523,Q9UJC3,Q8TAG9 30 +microtubule binding motor protein 0.4332043156358431 1.0220558224730878 0.3067544805851536 1.0 0.5711979983309757 19 Q9Y496,Q07866,Q02241,P52732,O75935,Q14807,O95239,P33176 8 +translation factor 0.5413816279285836 0.919514399275198 0.3578265775460878 1.0 0.6233108124996368 7 Q05639,Q06787,P51116,P51114 4 +GTPase-activating protein 0.4198614500782248 0.8550012991896401 0.3925504285116146 1.0 0.6555996847307378 17 P46940,Q8TC07,Q86VI3,A1A4S6,Q07960,Q4KMP7,Q15042 7 +cadherin 0.5989263330922214 0.7887378743115694 0.4302652266651807 1.0 0.707310108975825 4 P19022,O60245 2 +glycosidase 0.5137389516773081 0.5722770985508319 0.5671342623275684 1.0 0.8124294798416778 5 Q9BTY2 1 +SNARE protein 0.3951353468499036 0.5491196745014861 0.5829233241372569 1.0 0.8211615522629183 14 O15400,O43752,O60499,P51809 4 +scaffold/adaptor protein 0.2994133112723956 0.4909324561782036 0.6234742205849324 1.0 0.8507102830676716 97 Q9P2E9,Q8N3R9,Q9UQB8,Q5BKZ1,Q9Y5X2,Q96JJ3,Q96L92,Q9Y2W6,O14936,P07602,Q14168,Q96F07,Q7L576,O60749,Q4G0X4,P49792,Q9Y221,Q9NZW5,Q9Y5X1,P57105,O95219 21 +glycosyltransferase 0.3323069398286514 0.4888328380974233 0.6249600475047952 1.0 0.8507102830676716 31 Q68CQ7,Q96L58,Q16739,Q10472,Q8NAT1,P15291,O60512,P04843 8 +tight junction 0.4550947541883995 0.402743899135714 0.6871366357480122 1.0 0.8954762039570485 2 Q07157 1 +cysteine protease 0.3213720387765758 0.3646272590971479 0.7153896639558834 1.0 0.910346149541484 28 Q96K76,P17655,Q86UV5,Q8NB14,Q93009,O15484,Q99538,Q9UPT9 8 +DNA helicase 0.3612331207502868 0.3519106562600744 0.7249052672274781 1.0 0.910346149541484 13 Q96RR1,P12956 2 +transcription cofactor 0.3513590459068839 0.3087720787028065 0.7574949099448449 1.0 0.9248817219113344 13 O00625,Q7Z4V5 2 +zinc finger transcription factor 0.3693034412794858 0.2509425151505888 0.8018585534913185 1.0 0.9383126918084508 7 Q5SVZ6,Q9UBW7 2 +nucleic acid metabolism protein 0.4049197226122021 0.2319259430871348 0.816595534170875 1.0 0.9383126918084508 5 Q9NYF8,Q96FV9 2 +acetyltransferase 0.316844078727831 0.1685534783103297 0.8661478758043204 1.0 0.962489108091832 10 Q6N069 1 +chaperone 0.2640923882056001 0.1405028636584427 0.888262690062908 1.0 0.9684138197622564 80 P46379,Q9Y680,O15260,P49321,Q14203,Q7KZN9,P30533,Q13427,Q9BRT2,Q9H2H8,O95456,Q96KC8,Q8IXB1,Q9Y2R0,Q9Y3C6 15 +nucleotide phosphatase 0.3435993022548939 0.1374164873417267 0.8907015996578778 1.0 0.9684138197622564 6 Q8WVQ1,Q9H857 2 +kinase modulator 0.3351569650094487 0.0942794431369579 0.9248871791704738 1.0 0.9904011734019736 5 P54619,P13861 2 +heterotrimeric G-protein 0.2837094111172148 0.069684504852099 0.9444447751347512 1.0 0.9941591677459424 9 Q14344,P09471,P08754,Q9UBI6,P04899,Q6DD88,P63096,Q8NHH9 8 +translation elongation factor 0.2811897548884574 0.0640901237699205 0.9488984657694934 1.0 0.9941591677459424 12 Q8NE71,P29692,P43897,Q15029,Q9NUQ8,P49411,O43324,Q9UG63,Q7Z2Z2,P13639,P24534 11 +cytoskeletal protein 0.2836804268399411 0.0611978112420761 0.95120167284334 1.0 0.9941591677459424 7 P27105 1 +nucleotidyltransferase 0.2589334799340378 0.0235481006435817 0.9812130703425566 1.0 1.0 5 P31153,Q8NFW8,Q5TAX3,Q9NVV4 4 diff --git a/panther_protein_class/selections.json b/panther_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..5b68cb99df552d7a804446fb1be2aa8863b6b251 --- /dev/null +++ b/panther_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthase", "ATP-binding cassette (ABC) transporter", "C2H2 zinc finger transcription factor", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA metabolism protein", "DNA methyltransferase", "DNA polymerase processivity factor", "DNA topoisomerase", "DNA-binding transcription factor", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "G-protein", "G-protein coupled receptor", "G-protein modulator", "GTPase-activating protein", "Hsp90 family chaperone", "P53-like transcription factor", "RNA helicase", "RNA metabolism protein", "RNA methyltransferase", "RNA processing factor", "RNA splicing factor", "SNARE protein", "acetyltransferase", "actin and actin related protein", "actin binding motor protein", "actin or actin-binding cytoskeletal protein", "acyltransferase", "aldolase", "amino acid kinase", "amino acid transporter", "aminoacyl-tRNA synthetase", "antimicrobial response protein", "apolipoprotein", "aspartic protease", "basic helix-loop-helix transcription factor", "basic leucine zipper transcription factor", "cadherin", "calcium-binding protein", "calmodulin-related", "carbohydrate kinase", "cell adhesion molecule", "cell junction protein", "centromere DNA-binding protein", "chaperone", "chaperonin", "chromatin/chromatin-binding, or -regulatory protein", "cyclase", "cysteine protease", "cytokine", "cytoskeletal protein", "damaged DNA-binding protein", "deacetylase", "deaminase", "decarboxylase", "defense/immunity protein", "dehydratase", "dehydrogenase", "endodeoxyribonuclease", "endoribonuclease", "epimerase/racemase", "esterase", "exodeoxyribonuclease", "exoribonuclease", "extracellular matrix glycoprotein", "extracellular matrix protein", "extracellular matrix structural protein", "galactosidase", "general transcription factor", "glucosidase", "glycosidase", "glycosyltransferase", "growth factor", "guanyl-nucleotide exchange factor", "heterotrimeric G-protein", "histone", "histone modifying enzyme", "homeodomain transcription factor", "hydratase", "hydrolase", "immunoglobulin receptor superfamily", "immunoglobulin superfamily cell adhesion molecule", "integrin", "intercellular signal molecule", "intermediate filament binding protein", "ion channel", "isomerase", "kinase", "kinase activator", "kinase inhibitor", "kinase modulator", "ligase", "lipase", "lyase", "mRNA capping factor", "mRNA polyadenylation factor", "major histocompatibility complex protein", "membrane traffic protein", "membrane trafficking regulatory protein", "metalloprotease", "methyltransferase", "microtubule binding motor protein", "microtubule or microtubule-binding cytoskeletal protein", "mitochondrial carrier protein", "mutase", "non-motor actin binding protein", "non-motor microtubule binding protein", "non-receptor serine/threonine protein kinase", "nucleic acid metabolism protein", "nucleotide kinase", "nucleotide phosphatase", "nucleotidyltransferase", "oxidase", "oxidoreductase", "oxygenase", "peptide hormone", "peroxidase", "phosphatase", "phosphatase activator", "phosphatase inhibitor", "phosphatase modulator", "phosphodiesterase", "phospholipase", "primary active transporter", "primase", "protease", "protease inhibitor", "protein modifying enzyme", "protein phosphatase", "protein-binding activity modulator", "pyrophosphatase", "reductase", "replication origin binding protein", "ribosomal protein", "scaffold/adaptor protein", "secondary carrier transporter", "serine protease", "small GTPase", "structural protein", "tight junction", "transaminase", "transcription cofactor", "transfer/carrier protein", "transferase", "transketolase", "translation elongation factor", "translation factor", "translation initiation factor", "translation release factor", "translational protein", "transmembrane signal receptor", "transporter", "tubulin", "tyrosine protein kinase receptor", "ubiquitin-protein ligase", "vesicle coat protein", "viral or transposable element protein", "voltage-gated ion channel", "winged helix/forkhead transcription factor", "zinc finger transcription factor"], "available_proteins": ["AAK1", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD12", "ABHD6", "ABI1", "ABR", "ACAA1", "ACAA2", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGPAT1", "AGPAT5", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "ALYREF", "AMFR", "AMPD2", "ANAPC1", "ANAPC7", "ANGEL1", "ANKFY1", "ANKHD1", "ANKRD17", "ANLN", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APEH", "APLP2", "APOBEC3C", "APOC1", "APOL2", "APP", "APRT", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF7", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL6", "ARL6IP5", "ARPC3", "ARPC4", "ARRB2", "ARVCF", "AS3MT", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD2", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATL2", "ATL3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BAG2", "BAG6", "BAIAP2", "BAP18", "BAZ2A", "BCAP31", "BCAS2", "BCAT2", "BCKDK", "BCLAF1", "BCR", "BECN1", "BLM", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CABIN1", "CACYBP", "CAD", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX8", "CCAR1", "CCAR2", "CCDC12", "CCDC94", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2BP2", "CD320", "CD47", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC7", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CEBPZ", "CENPB", "CEP170", "CEP250", "CEPT1", "CETN2", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CKAP2", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPB", "CLPP", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNP", "COA3", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ3", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSE1L", "CSNK1A1", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC22", "CWC27", "CYB5B", "CYB5D2", "CYB5R3", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCAKD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDOST", "DDT", "DEK", "DENR", "DERL1", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC4", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENAH", "ENO1", "ENO2", "ENY2", "EPHA7", "EPHX1", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERH", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "FAHD1", "FAM3C", "FAM98A", "FAM98B", "FARSA", "FARSB", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FIGNL1", "FKBP14", "FKBP1A", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FLAD1", "FLII", "FMR1", "FN3KRP", "FNDC3A", "FNTA", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GFPT1", "GGH", "GID8", "GINS2", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLT1B", "GOPC", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAM", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACL1", "HADHB", "HAT1", "HBS1L", "HCCS", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HERC2", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HM13", "HMBS", "HMGA1", "HMGCL", "HMGCR", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATIP2", "HTATSF1", "HUWE1", "IAH1", "IARS", "IARS2", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "ISOC1", "ISOC2", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0368", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KLC1", "KLC2", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L1RE1", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRPAP1", "LRRC40", "LRRC47", "LRRC59", "LRRC8A", "LRRC8C", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTN1", "LYAR", "LYPLA1", "LZTFL1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MBOAT7", "MCCC1", "MCCC2", "MCFD2", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "MFAP1", "MFSD3", "MFSD5", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIF", "MIPEP", "MMAB", "MMS19", "MOB4", "MOGS", "MON2", "MORF4L1", "MORF4L2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS6", "MRPS7", "MRPS9", "MRRF", "MRS2", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTF2", "MTIF2", "MTOR", "MTPAP", "MUT", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA50", "NADSYN1", "NAE1", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCDN", "NCEH1", "NCK1", "NCKIPSD", "NCOA5", "ND1", "ND5", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK3", "NENF", "NFKBIL1", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOL9", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUMA1", "NUP107", "NUP153", "NUP155", "NUP160", "NUP210", "NUP214", "NUP37", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "NXN", "OAT", "OCIAD1", "OCLN", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OTUB1", "OXA1L", "OXCT1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPN1", "PACSIN2", "PACSIN3", "PAFAH1B2", "PAFAH1B3", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PAPOLA", "PARG", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDXP", "PDZD11", "PDZD8", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PUDP", "PUF60", "PURA", "PUS1", "PWP1", "PWWP2A", "PXMP2", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "RAB3GAP1", "RAB3GAP2", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL6", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM34", "RBM4", "RBM7", "RCL1", "RCN1", "RCN2", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIDA", "RIF1", "RIOK2", "RIPK1", "RNASEH2A", "RNF14", "RNF2", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RRM1", "RRM2", "RRM2B", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTN4IP1", "S100A10", "S100A11", "SACM1L", "SAE1", "SALL2", "SAMHD1", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC63", "SEH1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SKIV2L2", "SKP1", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC33A1", "SLC35B2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC6", "SMG1", "SMN1*", "SMNDC1", "SMPD4", "SMYD3", "SNAP29", "SNAP47", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAG9", "SPAST", "SPCS2", "SPCS3", "SPDL1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAM", "STAMBP", "STAT1", "STAT3", "STK4", "STOM", "STOML2", "STRAP", "STRBP", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SULT2A1", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAP1", "TAPBP", "TARS", "TARS2", "TARSL2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL3", "TBPL1", "TCEA1", "TCERG1", "TCOF1", "TCP1", "TCP11L1", "TDRKH", "TECR", "TERF2IP", "TES", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "THUMPD3", "TIAL1", "TIGAR", "TIMM10B", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM9", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLE3", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM259", "TMEM38B", "TMEM87A", "TMOD1", "TMOD3", "TMPO", "TMX2", "TMX3", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM22", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPT1", "TPX2", "TRAP1", "TRAPPC4", "TRIM13", "TRIM21", "TRIM24", "TRIM26", "TRIM27", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UGCG", "UGDH", "UGGT1", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNG", "UPF2", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRQ", "UROD", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP6", "UXS1", "UXT", "VAMP7", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VDAC1", "VDAC2", "VDAC3", "VKORC1L1", "VMP1", "VPS13A", "VPS13D", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS45", "VPS4A", "VPS4B", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "WARS", "WARS2", "WASF2", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR34", "WDR4", "WDR74", "WDR82", "WIZ", "WNK1", "WRN", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H15", "ZC3H4", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZFPL1", "ZFR", "ZMPSTE24", "ZMYM1", "ZMYM2", "ZMYM4", "ZNF281", "ZNF326", "ZNF598", "ZNF622", "ZNF644", "ZW10", "ZYX"], "leading_proteins": ["ABCB7", "ABCF1", "ABCF2", "ABCF3", "ACAT2", "ADAM17", "AHCYL1", "APLP2", "APP", "ARHGAP1", "ARHGAP10", "ARHGEF1", "ASNA1", "ATL2", "ATL3", "ATP5A1", "ATP5L", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "B3GALT6", "B4GALT1", "B4GALT3", "BAG6", "BAIAP2", "BCLAF1", "CANT1", "CAPN2", "CAPN5", "CASK", "CDH2", "CHMP1A", "CHMP5", "CLPP", "CLSTN3", "CMAS", "COA3", "COPS3", "COX15", "CPD", "CPT2", "CPVL", "CTSA", "CYB5D2", "CYFIP1", "CYFIP2", "DCTN1", "DCTN3", "DNAJC1", "DNAJC10", "DNM3", "DOCK1", "DOCK7", "ECE1", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF2", "EFL1", "EFTUD2", "EHD4", "ELMO2", "EPHX1", "EPS15", "ERAP1", "ERC1", "EXOC6", "EXOC7", "FECH", "FKBP7", "FMR1", "FUCA2", "FXR1", "FXR2", "GAK", "GALNT1", "GBF1", "GLA", "GLT8D1", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GOLGA2", "GPAM", "GPR107", "GPR108", "HDGFL2", "HLA-C", "HLA-F", "HMOX2", "HOOK1", "HOOK2", "HOOK3", "IGF2R", "IQGAP1", "IQGAP3", "ITSN2", "KCTD21", "KIF11", "KIF22", "KIF23", "KIF3A", "KIF4A", "KIF5B", "KLC1", "LAMB1", "LAPTM4A", "LGMN", "LMAN1", "LMBRD1", "LNPEP", "LRPAP1", "M6PR", "MAT2A", "MFAP1", "MGEA5", "MIA2", "MICU2", "MPP2", "MPP5", "MPP6", "MPV17", "MPV17L2", "MTPAP", "NAA16", "NAPG", "NASP", "NENF", "NIP7", "NPEPPS", "NT5DC2", "NUCB1", "NUCB2", "NUP93", "OPA1", "PCDH7", "PGRMC2", "PIR", "PLA2G15", "PLBD2", "PLD6", "POMGNT2", "PPIG", "PPIL1", "PPIL3", "PRCP", "PREB", "PREPL", "PRKAG1", "PRKAR2A", "PSAP", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMG1", "PXMP2", "RAB3GAP1", "RANBP2", "RAPGEF2", "RCN2", "RPN1", "RRBP1", "SCARB1", "SCARB2", "SCPEP1", "SDF4", "SEC13", "SIGMAR1", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC25A10", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A26", 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0000000000000000000000000000000000000000..d015e73227d9ff34ec4af61f600d6f0574166063 --- /dev/null +++ b/pharos_dto/df_merge.tsv @@ -0,0 +1,4 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +SLC superfamily of solute carriers 28 55 3.72324084081255 0.0001966817388834 18.888349514563107 44.33009708737864 2.1618907004737498 0.1690913715307362 9.633686860107934 5.825351940723624 1.7350998035598977 0.2760301582542676 1.0 0.0015773796188137 0.0017112034939487 0.0322368813739424 0.0032733486841773 +Receptor 12 33 3.0653468013613643 0.0021741773038059 8.25242718446602 27.344660194174757 1.739519175745715 0.1905542238199536 2.855648283399814 4.245230977176689 1.1861053756197322 0.2707159726336181 0.1086462299828856 9.429073712323974e-06 0.0005033540590971 0.0040448950832466 0.001841579682392 +SLC25 family of mitochondrial transporters 10 24 2.2244726492984945 0.0261166606973624 9.148058252427184 20.71359223300971 2.0411027534642088 0.1411881998864352 5.368907349966936 1.8276489510009888 1.309103123363054 0.2428184236965967 1.0 0.1604648724397155 0.2983459236646945 0.5955662992954859 0.0082637154660588 diff --git a/pharos_dto/metrics.json b/pharos_dto/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..a9428f48ba1f245e2c73f60d86a91a0cf852707f --- /dev/null +++ b/pharos_dto/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 2244, + "title": "Average number of proteins per term", + "value": 3.142602495543672 +} \ No newline at end of file diff --git a/pharos_dto/paths.json b/pharos_dto/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..7e89dd683ce99ca52148e38b2663abc5f619b612 --- /dev/null +++ b/pharos_dto/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_dto/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/pharos_dto/result.tsv b/pharos_dto/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..b9686da9de8fdbfa8137b9b3f2ad48a2c5456f4b --- /dev/null +++ b/pharos_dto/result.tsv @@ -0,0 +1,81 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +SLC superfamily of solute carriers 0.6479682737927891 3.72324084081255 0.0001966817388834 0.3568628181138528 0.0010360418358084 55 Q9BSK2,Q86VD7,Q9HC07,Q96H78,Q6NT16,Q8IXU6,O43772,Q01650,Q7L0J3,Q9HC21,Q9Y619,Q9Y666,Q9Y6C9,Q8N1S5,P11166,O00400,Q70HW3,O95563,Q9UBX3,Q9BQT8,P53985,Q8TB61,Q15758,P30825,P55011,Q9H2D1,P41440,Q9Y6M7 28 +Receptor 0.6649467847663753 3.0653468013613643 0.0021741773038059 0.992434564128123 0.0053146556315257 33 Q9NR77,P11717,Q14108,P20645,Q8WTV0,O75787,A6NIH7,Q13641,Q567V2,P57105,P39210,Q9UQB8 12 +SLC7 family 0.960999725350178 2.548668633664815 0.0108134992869404 0.9999999999746348 0.0187813408667912 2 P30825 1 +ROCK subfamily 0.9090909090909094 2.3333297202576393 0.0196308467414296 1.0 0.0306126616315275 2 O75116 1 +SLC25 family of mitochondrial transporters 0.6049861491068858 2.2244726492984945 0.0261166606973624 1.0 0.0385564385558429 24 Q9BSK2,Q86VD7,Q70HW3,Q9UBX3,Q96H78,Q9BQT8,O43772,Q9HC21,Q9Y619,Q9Y6C9 10 +AKT family 0.8338368580060412 2.012838639472091 0.0441316075126758 1.0 0.0595137690806439 2 P31751 1 +Phospholipase 0.8964190377039192 1.955622143958762 0.0505096823383306 1.0 0.0665944342933102 4 Q8NCC3 1 +SLC12 family of cation-coupled chloride transporters 0.8170832188959074 1.94023066607398 0.052351663226561 1.0 0.0686198202572447 2 P55011 1 +Enzyme modulator 0.372594411086981 1.9290426086913088 0.0537255728252474 1.0 0.0700176984571219 138 P07942,Q01105,P46379,P84095,Q86VI3,Q96N67,Q12834,P05067,O60313,O60518,Q06481,P42566,A1A4S6,Q8IUD2,Q5SVZ6,Q96ED9,Q9UBI6,O00410,Q14457,P27105,O95155,Q9NZM3,Q9UQ16,Q5T3I0,Q9Y4G8,Q96F07,Q99733,Q7L576,Q4G0X4,P11274,Q9H223,P49792,P46940,Q14139,Q9UNS2,Q15437,Q86VS8,Q6WCQ1,Q9UJC3,Q5TAQ9,Q9UBW7 41 +Protease inhibitor 0.6431843691372978 1.9171842397365728 0.0552145295581665 1.0 0.0714129131576516 14 P07942,P05067,Q06481 3 +DMPK family 0.9093406593406596 1.915371114556429 0.0554451921957417 1.0 0.0715836842676917 3 O75116,Q9Y5S2 2 +Mitochondrial amino acid transporter subfamily 0.8000224979650522 1.8736841865631504 0.0609739667754829 1.0 0.0769931625114581 6 O43772 1 +Signaling 0.5540228485641406 1.836276516806047 0.0663167710328762 1.0 0.0823090897111583 21 O15173,P43490,Q96JJ3,Q07820,Q8WUJ1,Q7Z4V5 6 +Dehydrogenase 0.4301761310892468 1.81125375475332 0.0701015806570768 1.0 0.086054675598731 59 P03886,P30837,O94788,O95831,P00390,Q96CU9,Q8N8N7 7 +Metalloprotease 0.4723796933934384 1.7715985014335518 0.0764612286406767 1.0 0.0924954162100693 38 P52888,Q9UIQ6,Q9NZ08,P42892,O75844,P55786 6 +Transporter 0.384385316713783 1.7598905196125842 0.0784263710611836 1.0 0.0941116452734203 225 Q9BSK2,Q86VD7,Q96EE3,O96008,Q6NT16,Q96H78,Q8IXU6,O43772,Q8N2H4,O43493,Q01650,Q7L0J3,Q9HD45,O75027,Q9HC21,Q9Y619,Q9Y666,Q9Y6C9,Q8N1S5,Q99805,P11166,O00400,O95563,Q70HW3,Q9UBX3,Q08379,Q9Y487,Q9BQT8,P53985,Q8TB61,P16615,Q9C0E2,O14678,Q15070,Q15758,P30825,Q7Z3B4,Q9HC07,P24390,P55011,O60499,Q9H2D1,P55735,P00846,Q9Y678,Q93050,O43752,Q8N1F7,O15400,O60749,P41440,Q9Y6M7,Q15075,Q15012,P51809,P35606,Q9NWU2,Q99523,P25705 59 +SLC3 and SLC7 families of heteromeric amino acid transporters (HATs) 0.8676155329672454 1.7548959067633427 0.0792771144528159 1.0 0.0947777543058705 3 P30825 1 +Lyase 0.5298603419763701 1.694525020496643 0.0901655613514698 1.0 0.105719288162682 22 P22830 1 +Actin binding motor protein 0.707745851197253 1.659595318595424 0.0969958907477943 1.0 0.1120316454910858 7 P67936,P09493 2 +CAMK group 0.6971585763292101 1.6130146152902234 0.1067413325571355 1.0 0.1213412108704216 7 Q14012,P54619,Q13555 3 +F-type and V-type ATPases 0.5413497307201004 1.6115332067788437 0.1070635555475132 1.0 0.1215843211784512 17 Q9Y487,Q93050,P00846 3 +V-type ATPase 0.670864085012224 1.5951789922718569 0.1106722151166779 1.0 0.1249237679687249 8 Q9Y487 1 +Guanyl-nucleotide exchange factor 0.7185050240813056 1.533622961687931 0.1251224360786405 1.0 0.1382445822552778 6 Q9Y4G8,P11274 2 +Miscellaneous SLC25 mitochondrial transporters 0.7193078824498732 1.5091668142372618 0.131256158542806 1.0 0.1440992268933741 2 Q9Y6C9 1 +Intracellular calcium-sensing protein 0.5356643341234165 1.483907803429095 0.1378333813949113 1.0 0.1497857433821877 16 Q9BRK5,Q02818,Q14257,Q8IYU8,P80303 5 +Calmodulin 0.5356643341234165 1.483907803429095 0.1378333813949113 1.0 0.1497857433821877 16 Q9BRK5,Q02818,Q14257,Q8IYU8,P80303 5 +CDK1 subfamily 0.710793737984067 1.471204442464752 0.1412358361433636 1.0 0.1528862596747265 2 P06493 1 +SET domain 0.7259189574814211 1.286177359897535 0.1983811705048102 1.0 0.2116820478425078 4 O96028,Q96L73 2 +Lipase 0.6585269708038393 1.279085697931218 0.2008668794352646 1.0 0.2142325463178392 6 Q8NCC3 1 +G-protein modulator 0.4166223451395282 1.2719640006536606 0.2033859102504756 1.0 0.2168161437539511 36 O60518,Q9NZM3,Q86VI3,P42566,A1A4S6,Q8IUD2,Q96N67,Q15437,Q6WCQ1,Q9Y4G8,Q96F07,P11274,Q7L576,Q9H223,O00410,P49792 16 +Antibacterial response protein 0.6608074704751393 1.2480193991007638 0.2120239531001062 1.0 0.2257029178162421 2 P40222 1 +Mitochondrial nucleotide transporter subfamily 0.5453915433958104 1.235758181097301 0.2165484637791108 1.0 0.2301917350641046 11 Q9BSK2,Q86VD7,Q70HW3,Q9HC21 4 +Epigenetic regulator 0.4369674748986923 1.2127450150512906 0.2252273235286577 1.0 0.2393040312491988 29 O96028,Q8NB78 2 +Esterase 0.5297305300387509 1.187713234587698 0.2349464078505374 1.0 0.2495124179917681 12 P50897 1 +Calcium-binding protein 0.4510838307638724 1.1655172852367452 0.2438096675936603 1.0 0.2588026935100159 22 Q9BRK5,Q02818,Q14257,Q9BQT9,Q8IYU8,P80303 6 +Kinase modulator 0.4621126388720807 1.1186182374783618 0.2633030396788225 1.0 0.2790987345485488 17 Q86VS8,Q9UJC3,Q5SVZ6,Q96ED9,Q16543,Q9UBW7 6 +Extracellular structure 0.5238954507739946 1.0952331666634327 0.2734144987745435 1.0 0.2891338997408462 10 P55081,O75718 2 +PKN family 0.6146663004668984 1.043284721187825 0.2968164452443369 1.0 0.3134381661780198 2 Q16513 1 +DNA helicase 0.4550198499183531 0.8724599989280344 0.3829574811224805 1.0 0.4026975574690001 14 Q96RR1,P12956,Q14566 3 +Cell-cell junction 0.6043283047199245 0.8092276182087522 0.4183842315985584 1.0 0.4393328103449532 4 Q5EBL8,Q16625 2 +Oxidoreductase 0.3093152867616796 0.7874508946202159 0.4310179634937277 1.0 0.4521759280411055 126 P03886,O15254,Q16850,P30837,O94788,O15260,Q15392,O95831,O75380,P00390,Q96CU9,Q8N8N7 12 +Protease 0.3134161471373508 0.7554700011212777 0.4499670254471897 1.0 0.4711740574444674 117 P42785,O14773,Q8TCT8,P55786,Q9HB40,Q9UIQ6,P02786,Q9Y6M1,P42892,Q8NHP8,P10619,P22695,O15484,Q9H300,Q9H3G5,Q96K76,P52888,P17655,Q9NZ08,Q93009,O75844,Q9UPT9 22 +SNARE protein 0.4394220881924378 0.737464340184065 0.4608400211031163 1.0 0.481660459876755 13 O15400,O43752,O60499,P51809 4 +Mitochondrial di- and tri-carboxylic acid transporter subfamily 0.563156423786508 0.6560181507983451 0.5118124457232174 1.0 0.5327027496302874 4 Q9UBX3 1 +Kinase inhibitor 0.5078737869910097 0.651583661276635 0.514669790725502 1.0 0.5351802643132653 6 Q9UBW7 1 +Tight junction 0.5768771148499028 0.635670868149179 0.5249909679359313 1.0 0.545154896829352 3 Q16625 1 +F-type ATPase 0.4430267010215251 0.6202993742583206 0.5350607068234834 1.0 0.5550976542357359 9 P00846 1 +Hydrolase 0.3053041327562451 0.5879926476607452 0.5565372278476151 1.0 0.5771116170471572 107 P16278,Q8N2A8,P50897,Q9NX62,Q9UMR5,Q9NPH0,P11117,P10586,O43681,O43865,P00813,Q8NCC3 12 +HDAC class I 0.5020598736610726 0.5720723475786397 0.5672729620269941 1.0 0.5877010742329524 2 Q92769 1 +Acetyltransferase 0.3526393996693098 0.5216405782119866 0.6019206047635097 1.0 0.6213016729941655 24 P23786,Q96N66,Q6N069,Q9BWD1 4 +AUR family 0.4877780829442363 0.518147828170268 0.6043551322541287 1.0 0.6235277778290873 2 O14965 1 +Nucleotide phosphatase 0.4390617057122312 0.4912329240106445 0.6232617150060242 1.0 0.6418537349580167 7 O43681,Q9BX68,Q9H857 3 +Small GTPase 0.3396366133443799 0.4446193518960206 0.6565948600364184 1.0 0.6754899547326431 25 O60313,P84095,Q9UQ16,P11233,Q9NVA2,Q15382,O15397 7 +Translation elongation factor 0.4910689749931492 0.4117003628697844 0.6805590589892547 1.0 0.6986159782122084 4 P29692,Q53EL6,P43897 3 +Microtubule binding motor protein 0.3675667961731974 0.4109590330880363 0.6811025744452195 1.0 0.6988542190466724 14 Q9Y496,Q02241,P52732,Q14807,O95239,P33176 6 +Cadherin 0.4432848118648622 0.3642158074846429 0.7156968638139953 1.0 0.731340511110476 2 Q14126 1 +Helicase 0.326222007994437 0.358678170805004 0.7198358604135162 1.0 0.7352351710368368 24 Q96RR1,P12956,Q14566 3 +Histone deacetylase 0.4884615384615401 0.3521370157736499 0.7247355094201806 1.0 0.7392302196085843 3 Q92769,Q13547 2 +G-protein 0.3020752273634965 0.3472541299058501 0.728400408101405 1.0 0.7422936038962548 36 O60313,P84095,Q9UQ16,P11233,Q9UBI6,Q5TAQ9,Q9NVA2,Q15382,O15397 9 +IKK family 0.4218621257896104 0.2992683328564875 0.7647353146950711 1.0 0.7779084524822029 2 O15111 1 +Non-motor microtubule binding protein 0.3143478535027738 0.2876808138693639 0.7735910777654522 1.0 0.7865602077506456 21 Q15555,O43663,Q9UH99,Q96CW5 4 +Phosphatase 0.2971030317265516 0.2867700613091991 0.7742883881569418 1.0 0.7869126553551528 33 Q9NPH0,P10586,O43681,Q9NX62 4 +Glycosyltransferase 0.3104171604500254 0.2705199543818303 0.7867602676266161 1.0 0.7992259124283054 25 Q16739,Q10472,Q8NAT1,P15291,O60512,P04843 6 +Cysteine protease 0.2853344374542668 0.2647659156437678 0.7911897954568652 1.0 0.8033619461562016 43 Q96RU2,Q96K76,Q8TC07,P17655,Q8NB14,Q93009,Q4KMP7,O15484,Q99538,Q8NHP8,Q9UPT9 11 +Cell adhesion 0.4076415612974187 0.2387533694622411 0.8112968303608186 1.0 0.8215478733437169 5 Q96MG7,Q13740,Q14126,Q14574 4 +Immune response 0.3832829254880433 0.2298337179082777 0.8182209828779685 1.0 0.8274393355467153 6 Q6AI08,Q6P2E9,P40222,Q9NUQ3,P78318 5 +STE group 0.352310231023108 0.2029064496514434 0.8392081530521851 1.0 0.8475171446665631 7 Q13043,Q02750,Q13177,O95747,O96013,Q9P289 6 +STE20 family 0.3522133626615418 0.1553144688466068 0.876573409537454 1.0 0.8840587555065378 6 Q13043,Q13177,O95747,O96013,Q9P289 5 +Non-protein kinase 0.2877299798130641 0.1520843467554826 0.8791204100686096 1.0 0.886229200446523 22 P35790,P55263 2 +Translation initiation factor 0.2847512208011001 0.1382887222369843 0.890012238225433 1.0 0.8964037085178956 22 O75153 1 +Kinase activator 0.3846153846153867 0.1262134933349524 0.8995629306443267 1.0 0.9056165169878282 3 Q16543,O95163 2 +ABCC subfamily 0.3391925295248512 0.1181829359739796 0.9059227103161552 1.0 0.9116101174661222 2 O15439 1 +SLC39 family of metal ion transporters 0.3546492108205418 0.0875837783867113 0.9302074955991212 1.0 0.934371360843522 3 Q8N1S5 1 +Chromodomain 0.3431318681318701 0.075781562071961 0.9395928852725844 1.0 0.9433764807837492 3 Q13185,P45973 2 +Membrane trafficking regulatory protein 0.2698296581387586 0.0706006701697329 0.9437155770273038 1.0 0.9469767986605816 24 Q15075,P55735,O60749,P24390 4 +Tudor domain 0.2974457566602525 0.0700331611651575 0.9441672656325696 1.0 0.9469767986605816 2 Q16637 1 +Heterotrimeric G-protein 0.2837094111172148 0.069684504852099 0.9444447751347512 1.0 0.9469767986605816 9 Q14344,P09471,P08754,Q9UBI6,P04899,Q6DD88,P63096,Q8NHH9 8 +Translation factor 0.26532904876753 0.0554344193288365 0.9557923753255682 1.0 0.9579267933142362 27 O75153 1 +Methyl-lysine/arginine binding protein 0.2976910390324399 0.0502693355190516 0.9599077595742004 1.0 0.9616218805734402 5 P83916,Q13185,P45973,Q16637 4 +RNA helicase 0.2433250756950215 0.002923119013016 0.9976676917915754 1.0 0.9985576718913004 10 Q6P158,Q7Z478,Q92900,Q9BQ75,Q8IY37,O43143,Q08211,Q14562,Q92620 9 diff --git a/pharos_dto/selections.json b/pharos_dto/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..fed3e17bc232c60da43eedc4474f881f62ca429a --- /dev/null +++ b/pharos_dto/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase", "1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1", "10 kDa heat shock protein, mitochondrial", "116 kDa U5 small nuclear ribonucleoprotein component", "14-3-3 protein beta/alpha", "14-3-3 protein epsilon", "14-3-3 protein eta", "14-3-3 protein gamma", "14-3-3 protein theta", "14-3-3 protein zeta/delta", "2',3'-cyclic-nucleotide 3'-phosphodiesterase", "2',5'-phosphodiesterase 12", "2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial", "2-hydroxyacyl-CoA lyase 1", "26S proteasome non-ATPase regulatory subunit 1", "26S proteasome non-ATPase regulatory subunit 12", "26S proteasome non-ATPase regulatory subunit 13", "26S proteasome non-ATPase regulatory subunit 14", "26S proteasome non-ATPase regulatory subunit 2", "26S proteasome non-ATPase regulatory subunit 3", "26S proteasome non-ATPase regulatory subunit 4", "26S proteasome non-ATPase regulatory subunit 7", "26S proteasome non-ATPase regulatory subunit 8", "26S proteasome non-ATPase regulatory subunit 9", "26S proteasome regulatory subunit 10B", "26S proteasome regulatory subunit 4", "26S proteasome regulatory subunit 6A", "26S proteasome regulatory subunit 6B", "26S proteasome regulatory subunit 7", "26S proteasome regulatory subunit 8", "28S ribosomal protein S11, mitochondrial", "28S ribosomal protein S16, mitochondrial", "28S ribosomal protein S2, mitochondrial", "28S ribosomal protein S24, mitochondrial", "28S ribosomal protein S27, mitochondrial", "28S ribosomal protein S29, mitochondrial", "28S ribosomal protein S35, mitochondrial", "28S ribosomal protein S5, mitochondrial", "28S ribosomal protein S7, mitochondrial", "3'(2'),5'-bisphosphate nucleotidase 1", "3-hydroxyacyl-CoA dehydrogenase type-2", "3-hydroxyisobutyrate dehydrogenase, mitochondrial", "3-hydroxyisobutyryl-CoA hydrolase, mitochondrial", "3-ketoacyl-CoA thiolase, mitochondrial", "3-ketoacyl-CoA thiolase, peroxisomal", "3-mercaptopyruvate sulfurtransferase", "39S ribosomal protein L1, mitochondrial", "39S ribosomal protein L11, mitochondrial", "39S ribosomal protein L12, mitochondrial", "39S ribosomal protein L13, mitochondrial", "39S ribosomal protein L14, mitochondrial", "39S ribosomal protein L16, mitochondrial", "39S ribosomal protein L17, mitochondrial", "39S ribosomal protein L19, mitochondrial", "39S ribosomal protein L2, mitochondrial", "39S ribosomal protein L20, mitochondrial", "39S ribosomal protein L21, mitochondrial", "39S ribosomal protein L22, mitochondrial", "39S ribosomal protein L24, mitochondrial", "39S ribosomal protein L38, mitochondrial", "39S ribosomal protein L39, mitochondrial", "39S ribosomal protein L41, mitochondrial", "39S ribosomal protein L43, mitochondrial", "39S ribosomal protein L44, mitochondrial", "39S ribosomal protein L47, mitochondrial", "39S ribosomal protein L48, mitochondrial", "39S ribosomal protein L49, mitochondrial", "39S ribosomal protein L9, mitochondrial", "39S ribosomal protein S18a, mitochondrial", "4-aminobutyrate aminotransferase, mitochondrial", "4-trimethylaminobutyraldehyde dehydrogenase", "40S ribosomal protein S10", "40S ribosomal protein S11", "40S ribosomal protein S12", "40S ribosomal protein S13", "40S ribosomal protein S14", "40S ribosomal protein S15", "40S ribosomal protein S15a", "40S ribosomal protein S17", "40S ribosomal protein S18", "40S ribosomal protein S19", "40S ribosomal protein S2", "40S ribosomal protein S20", "40S ribosomal protein S21", "40S ribosomal protein S23", "40S ribosomal protein S24", "40S ribosomal protein S28", "40S ribosomal protein S3", "40S ribosomal protein S3a", "40S ribosomal protein S4, X isoform", "40S ribosomal protein S5", "40S ribosomal protein S6", "40S ribosomal protein S7", "40S ribosomal protein S8", "40S ribosomal protein S9", "40S ribosomal protein SA", "45 kDa calcium-binding protein", "4F2 cell-surface antigen heavy chain", "5'-AMP-activated protein kinase catalytic subunit alpha-2", "5'-AMP-activated protein kinase subunit gamma-1", "5'-nucleotidase domain-containing protein 1", "5'-nucleotidase domain-containing protein 2", "5-methylcytosine rRNA methyltransferase NSUN4", "55 kDa erythrocyte membrane protein", "6-phosphogluconate dehydrogenase, decarboxylating", "6-phosphogluconolactonase", "60 kDa SS-A/Ro ribonucleoprotein", "60S ribosomal protein L10", "60S ribosomal protein L10a", "60S ribosomal protein L11", "60S ribosomal protein L12", "60S ribosomal protein L13", "60S ribosomal protein L13a", "60S ribosomal protein L14", "60S ribosomal protein L15", "60S ribosomal protein L18", "60S ribosomal protein L19", "60S ribosomal protein L21", "60S ribosomal protein L22", "60S ribosomal protein L23", "60S ribosomal protein L23a", "60S ribosomal protein L24", "60S ribosomal protein L26", "60S ribosomal protein L27", "60S ribosomal protein L27a", "60S ribosomal protein L28", "60S ribosomal protein L29", "60S ribosomal protein L3", "60S ribosomal protein L30", "60S ribosomal protein L31", "60S ribosomal protein L32", "60S ribosomal protein L35", "60S ribosomal protein L35a", "60S ribosomal protein L36", "60S ribosomal protein L36a", "60S ribosomal protein L37", "60S ribosomal protein L38", "60S ribosomal protein L5", "60S ribosomal protein L6", "60S ribosomal protein L7", "60S ribosomal protein L7-like 1", "60S ribosomal protein L7a", "60S ribosomal protein L8", "60S ribosomal protein L9", "7,8-dihydro-8-oxoguanine triphosphatase", "7-dehydrocholesterol reductase", "7-methylguanosine phosphate-specific 5'-nucleotidase", "A-kinase anchor protein 1, mitochondrial", "ABCB subfamily", "ABCC subfamily", "ABCD subfamily of peroxisomal ABC transporters", "ADP-dependent glucokinase", "ADP-ribose pyrophosphatase, mitochondrial", "ADP-sugar pyrophosphatase", "ADP/ATP translocase 1", "ADP/ATP translocase 2", "ADP/ATP translocase 3", "AFG3-like protein 2", "AGC group", "AH receptor-interacting protein", "AK1 subfamily", "AK2 subfamily", "AK3 subfamily", "AKT family", "AMP deaminase 2", "AMPK subfamily", "AP-1 complex subunit beta-1", "AP-1 complex subunit gamma-1", "AP-1 complex subunit mu-1", "AP-1 complex subunit sigma-1A", "AP-1 complex subunit sigma-2", "AP-2 complex subunit alpha-1", "AP-2 complex subunit alpha-2", "AP-2 complex subunit beta", "AP-2 complex subunit mu", "AP-2 complex subunit sigma", "AP-3 complex subunit beta-1", "AP-3 complex subunit delta-1", "AP-3 complex subunit mu-1", "AP-3 complex subunit sigma-1", "AP-4 complex subunit mu-1", "AT-rich interactive domain-containing protein 3B", "ATP synthase F(0) complex subunit B1, mitochondrial", "ATP synthase mitochondrial F1 complex assembly factor 1", "ATP synthase subunit a", "ATP synthase subunit alpha, mitochondrial", "ATP synthase subunit beta, mitochondrial", "ATP synthase subunit d, mitochondrial", "ATP synthase subunit e, mitochondrial", "ATP synthase subunit f, mitochondrial", "ATP synthase subunit gamma, mitochondrial", "ATP synthase-coupling factor 6, mitochondrial", "ATP-binding cassette sub-family B member 10, mitochondrial", "ATP-binding cassette sub-family B member 6, mitochondrial", "ATP-binding cassette sub-family B member 7, mitochondrial", "ATP-binding cassette sub-family B member 8, mitochondrial", "ATP-binding cassette sub-family D member 3", "ATP-binding cassette sub-family D member 4", "ATP-binding cassette sub-family F member 1", "ATP-binding cassette sub-family F member 2", "ATP-binding cassette sub-family F member 3", "ATP-binding cassette transporter family", "ATP-citrate synthase", "ATP-dependent 6-phosphofructokinase, muscle type", "ATP-dependent 6-phosphofructokinase, platelet type", "ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial", "ATP-dependent DNA helicase Q1", "ATP-dependent PFK group I subfamily", "ATP-dependent RNA helicase A", "ATP-dependent RNA helicase DHX29", "ATP-dependent RNA helicase DHX8", "ATP-dependent zinc metalloprotease YME1L1", "ATPase ASNA1", "ATPase family AAA domain-containing protein 2", "ATPase family AAA domain-containing protein 3A", "ATPase family AAA domain-containing protein 3B", "ATPase inhibitor, mitochondrial", "AUR family", "Abl interactor 1", "Acetolactate synthase-like protein", "Acetyl-CoA acetyltransferase, cytosolic", "Acetyl-CoA acetyltransferase, mitochondrial", "Acetyl-coenzyme A transporter 1", "Acetyltransferase", "Acid ceramidase", "Acidic leucine-rich nuclear phosphoprotein 32 family member A", "Acidic leucine-rich nuclear phosphoprotein 32 family member B", "Acidic leucine-rich nuclear phosphoprotein 32 family member E", "Aconitate hydratase, mitochondrial", "Actin and actin related protein", "Actin binding motor protein", "Actin family cytoskeletal protein", "Actin-like protein 6A", "Actin-related protein 10", "Actin-related protein 2", "Actin-related protein 2/3 complex subunit 3", "Actin-related protein 2/3 complex subunit 4", "Actin-related protein 3", "Actin-related protein 6", "Actin-related protein 8", "Activating signal cointegrator 1", "Active breakpoint cluster region-related protein", "Acyl-CoA dehydrogenase family member 10", "Acyl-CoA dehydrogenase family member 9, mitochondrial", "Acyl-CoA synthetase family member 3, mitochondrial", "Acyl-coenzyme A thioesterase 8", "Acyl-coenzyme A thioesterase 9, mitochondrial", "Acylamino-acid-releasing enzyme", "Acylpyruvase FAHD1, mitochondrial", "Acyltransferase", "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "Adenosine deaminase", "Adenosine kinase", "Adenosylhomocysteinase", "Adenylate kinase 2, mitochondrial", "Adenylate kinase 4, mitochondrial", "Adenylate kinase family", "Adenylate kinase isoenzyme 1", "Adenylosuccinate lyase", "Adenylosuccinate synthetase isozyme 2", "Adenylyl cyclase-associated protein 1", "Afadin", "Aflatoxin B1 aldehyde reductase member 2", "Alanine aminotransferase 2", "Alanine--tRNA ligase, cytoplasmic", "Alanine--tRNA ligase, mitochondrial", "Alanine/serine/cysteine transporter subfamily", "Alanyl-tRNA editing protein Aarsd1", "Alcohol dehydrogenase [NADP(+)]", "Alcohol dehydrogenase class-3", "Aldehyde dehydrogenase X, mitochondrial", "Aldehyde dehydrogenase family 16 member A1", "Aldehyde dehydrogenase, mitochondrial", "Aldose 1-epimerase", "Aldose reductase", "Alpha-adducin", "Alpha-aminoadipic semialdehyde dehydrogenase", "Alpha-centractin", "Alpha-enolase", "Alpha-globin transcription factor CP2", "Alpha-parvin", "Alpha-soluble NSF attachment protein", "Alpha-taxilin", "Amidophosphoribosyltransferase", "Aminoacyl tRNA synthase complex-interacting multifunctional protein 1", "Aminoacyl-tRNA synthetase", "Amyloid-beta A4 protein", "Amyloid-like protein 2", "Anaphase-promoting complex subunit 1", "Ancient ubiquitous protein 1", "Anion channel tweety (tweety) family", "Anion exchange protein 2", "Anion exchangers", "Annexin", "Anoctamin-6", "Antibacterial response protein", "Antigen peptide transporter 1", "Ap2-associated protein kinase 1", "Apolipoprotein", "Apolipoprotein L2", "Apoptosis-inducing factor 1, mitochondrial", "Arfaptin-1", "Arfaptin-2", "Arginase-2, mitochondrial", "Armadillo repeat protein deleted in velo-cardio-facial syndrome", "Arsenite methyltransferase", "Asparagine synthetase [glutamine-hydrolyzing]", "Asparagine--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, cytoplasmic", "Aspartate--tRNA ligase, mitochondrial", "Aspartic protease", "Ataxin-2-like protein", "Atlastin-2", "Atlastin-3", "Atp-dependent 6-phosphofructokinase, liver type", "Atypical SLC22B subfamily", "Atypical group", "Aurora kinase a", "Aurora kinase b", "Autophagy protein 5", "B-cell receptor-associated protein 31", "BTB/POZ domain-containing protein KCTD12", "BTB/POZ domain-containing protein KCTD21", "BUB family", "Basic leucine zipper and W2 domain-containing protein 1", "Basic leucine zipper and W2 domain-containing protein 2", "Basic leucine zipper transcription factor", "Bcl-2 homologous antagonist/killer", "Bcl-2-associated transcription factor 1", "Beclin-1", "Beta-1,4-galactosyltransferase 1", "Beta-1,4-galactosyltransferase 3", "Beta-arrestin-2", "Beta-galactosidase", "Beta-hexosaminidase subunit alpha", "Beta-hexosaminidase subunit beta", "Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1", "Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6", "Bifunctional coenzyme A synthase", "Bifunctional epoxide hydrolase 2", "Bifunctional glutamate/proline--tRNA ligase", "Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial", "Bifunctional purine biosynthesis protein PURH", "Biliverdin reductase A", "Biotin--protein ligase", "Bleomycin hydrolase", "Brain-specific angiogenesis inhibitor 1-associated protein 2", "Branched-chain-amino-acid aminotransferase, mitochondrial", "Breakpoint cluster region protein", "Breast cancer type 1 susceptibility protein", "Bromodomain", "Bromodomain-containing protein 2", "Bromodomain-containing protein 3", "Bromodomain-containing protein 4", "C-1-tetrahydrofolate synthase, cytoplasmic", "C-Jun-amino-terminal kinase-interacting protein 4", "C-terminal-binding protein 1", "C-terminal-binding protein 2", "C2H2 zinc finger transcription factor", "CAAX prenyl protease 1 homolog", "CAD protein", "CAMK group", "CAMK1 family", "CAMK2 family", "CAMKL family", "CASK family", "CCAAT/enhancer-binding protein zeta", "CCK4 family", "CCR4-NOT transcription complex subunit 1", "CCR4-NOT transcription complex subunit 3", "CCR4-NOT transcription complex subunit 4", "CCR4-NOT transcription complex subunit 7", "CD166 antigen", "CD2 antigen cytoplasmic tail-binding protein 2", "CDC7 family", "CDK family", "CDK1 subfamily", "CDK4 subfamily", "CDK5 subfamily", "CDK9 subfamily", "CDKN2A-interacting protein", "CK1 family", "CK1 group", "CK2 family", "CLIP-associating protein 1", "CLIP-associating protein 2", "CMGC group", "COP9 signalosome complex subunit 3", "COP9 signalosome complex subunit 5", "COP9 signalosome complex subunit 6", "COP9 signalosome complex subunit 8", "CSK family", "CTP synthase 1", "CTP synthase 2", "Ca2+-ATPases", "Cadherin", "Calcineurin-binding protein cabin-1", "Calcium homeostasis endoplasmic reticulum protein", "Calcium uniporter protein, mitochondrial", "Calcium uptake protein 1, mitochondrial", "Calcium uptake protein 2, mitochondrial", "Calcium-binding mitochondrial carrier protein Aralar1", "Calcium-binding mitochondrial carrier protein Aralar2", "Calcium-binding mitochondrial carrier protein SCaMC-1", "Calcium-binding mitochondrial carrier protein SCaMC-2", "Calcium-binding protein", "Calcium-binding protein 39", "Calcium-dependent chloride channel (ca-clc) family", "Calcium-transporting ATPase type 2C member 1", "Calcium/calmodulin-dependent protein kinase type 1", "Calcium/calmodulin-dependent protein kinase type ii subunit gamma", "Calcyclin-binding protein", "Calmegin", "Calmodulin", "Calmodulin-3", "Calnexin", "Calpain-1 catalytic subunit", "Calpain-2 catalytic subunit", "Calpain-5", "Calponin-3", "Calreticulin", "Calsyntenin-3", "Calumenin", "Camp-dependent protein kinase catalytic subunit alpha", "Cancer-related nucleoside-triphosphatase", "Caprin-1", "Carbohydrate kinase", "Carbohydrate sulfotransferase 14", "Carnitine O-palmitoyltransferase 1, liver isoform", "Carnitine O-palmitoyltransferase 2, mitochondrial", "Cartilage-associated protein", "Casein kinase II subunit alpha", "Casein kinase II subunit alpha'", "Casein kinase i isoform alpha", "Casein kinase ii subunit beta", "Catechol O-methyltransferase", "Catechol O-methyltransferase domain-containing protein 1", "Catenin alpha-1", "Catenin delta-1", "Cation-dependent mannose-6-phosphate receptor", "Cation-independent mannose-6-phosphate receptor", "Cell adhesion", "Cell cycle and apoptosis regulator protein 2", "Cell division control protein 42 homolog", "Cell division control protein 45 homolog", "Cell division cycle 7-related protein kinase", "Cell division cycle and apoptosis regulator protein 1", "Cell division cycle protein 20 homolog", "Cell-cell junction", "Cellular structure", "Cellular tumor antigen p53", "Centrin-2", "Centromere-associated protein E", "Centromere/kinetochore protein zw10 homolog", "Centrosomal protein of 170 kDa", "Centrosome-associated protein CEP250", "Ceramide glucosyltransferase", "Chaperone", "Chaperonin", "Charged multivesicular body protein 3", "Charged multivesicular body protein 4b", "Charged multivesicular body protein 5", "Charged multivesicular body protein 7", "Chitobiosyldiphosphodolichol beta-mannosyltransferase", "Chloride channel CLIC-like protein 1", "Chloride channel family", "Chloride intracellular channel protein 1", "Chloride intracellular channel protein 4", "Chloride transport protein 6", "Choline kinase alpha", "Choline/ethanolamine kinase family", "Choline/ethanolaminephosphotransferase 1", "Chondroitin sulfate glucuronyltransferase", "Chromatin assembly factor 1 subunit A", "Chromatin assembly factor 1 subunit B", "Chromatin target of PRMT1 protein", "Chromatin/chromatin-binding protein", "Chromobox protein homolog 1", "Chromobox protein homolog 3", "Chromobox protein homolog 5", "Chromodomain", "Chromosome-associated kinesin KIF4A", "Cilia- and flagella-associated protein 20", "Citrate synthase, mitochondrial", "ClC-3/CLCN3 subfamily", "ClC-6/CLCN6 subfamily", "ClC-7/CLCN7 subfamily", "Class I transporters", "Clathrin heavy chain 1", "Clathrin light chain A", "Clathrin light chain B", "Cleavage and polyadenylation specificity factor subunit 1", "Cleavage and polyadenylation specificity factor subunit 3", "Cleavage and polyadenylation specificity factor subunit 5", "Cleavage and polyadenylation specificity factor subunit 6", "Cleavage and polyadenylation specificity factor subunit 7", "Cleavage stimulation factor subunit 2", "Cleavage stimulation factor subunit 3", "Cleft lip and palate transmembrane protein 1", "Cleft lip and palate transmembrane protein 1-like protein", "Clustered mitochondria protein homolog", "Coactosin-like protein", "Coatomer subunit alpha", "Coatomer subunit beta", "Coatomer subunit beta'", "Coatomer subunit delta", "Coatomer subunit epsilon", "Coatomer subunit gamma-1", "Coatomer subunit gamma-2", "Coatomer subunit zeta-1", "Cohesin subunit SA-1", "Cohesin subunit SA-2", "Coilin", "Cold-inducible RNA-binding protein", "Collectin-12", "Condensin complex subunit 1", "Condensin-2 complex subunit D3", "Core histone macro-H2A.1", "Core histone macro-H2A.2", "Coronin-1B", "Coronin-1C", "Coronin-7", "Creatine kinase B-type", "Creatine kinase U-type, mitochondrial", "Crooked neck-like protein 1", "Cullin-1", "Cullin-2", "Cullin-4B", "Cullin-5", "Cullin-associated NEDD8-dissociated protein 1", "Cullin-associated NEDD8-dissociated protein 2", "Cyclase", "Cyclic AMP-dependent transcription factor ATF-7", "Cyclin-dependent kinase 1", "Cyclin-dependent kinase 11b", "Cyclin-dependent kinase 16", "Cyclin-dependent kinase 2", "Cyclin-dependent kinase 4", "Cyclin-dependent kinase 6", "Cyclin-dependent kinase 9", "Cyclin-dependent-like kinase 5", "Cyclin-g-associated kinase", "Cystathionine gamma-lyase", "Cystatin-B", "Cysteine and glycine-rich protein 2", "Cysteine and histidine-rich domain-containing protein 1", "Cysteine desulfurase, mitochondrial", "Cysteine protease", "Cysteine protease ATG4B", "Cysteine protease inhibitor", "Cysteine--tRNA ligase, cytoplasmic", "Cytochrome b-c1 complex subunit 1, mitochondrial", "Cytochrome b-c1 complex subunit 2, mitochondrial", "Cytochrome b-c1 complex subunit 7", "Cytochrome b-c1 complex subunit 9", "Cytochrome b5 type B", "Cytochrome c oxidase subunit 1", "Cytochrome c oxidase subunit 2", "Cytochrome c oxidase subunit 5A, mitochondrial", "Cytochrome c oxidase subunit 5B, mitochondrial", "Cytochrome c oxidase subunit 7A-related protein, mitochondrial", "Cytochrome c oxidase subunit 7A2, mitochondrial", "Cytochrome c oxidase subunit 7C, mitochondrial", "Cytochrome c oxidase subunit NDUFA4", "Cytochrome c-type heme lyase", "Cytokine", "Cytokine receptor", "Cytoplasmic FMR1-interacting protein 1", "Cytoplasmic FMR1-interacting protein 2", "Cytoplasmic aconitate hydratase", "Cytoplasmic dynein 1 heavy chain 1", "Cytoplasmic dynein 1 intermediate chain 2", "Cytoplasmic dynein 1 light intermediate chain 1", "Cytoplasmic dynein 1 light intermediate chain 2", "Cytoplasmic dynein 2 heavy chain 1", "Cytoskeleton-associated protein 5", "Cytosol aminopeptidase", "Cytosolic 5'-nucleotidase 3A", "Cytosolic acyl coenzyme A thioester hydrolase", "Cytosolic non-specific dipeptidase", "Cytosolic purine 5'-nucleotidase", "D-3-phosphoglycerate dehydrogenase", "D-dopachrome decarboxylase", "DCK/DGK family", "DDB1- and CUL4-associated factor 13", "DDB1- and CUL4-associated factor 8", "DMPK family", "DNA (cytosine-5)-methyltransferase 1", "DNA binding protein", "DNA dC->dU-editing enzyme APOBEC-3C", "DNA damage-binding protein 1", "DNA glycosylase", "DNA helicase", "DNA ligase", "DNA ligase 1", "DNA ligase 3", "DNA methyltransferase", "DNA mismatch repair protein Msh2", "DNA mismatch repair protein Msh3", "DNA mismatch repair protein Msh6", "DNA polymerase alpha subunit B", "DNA polymerase delta subunit 2", "DNA polymerase epsilon subunit 2", "DNA polymerase epsilon subunit 4", "DNA polymerase processivity factor", "DNA polymerase subunit gamma-1", "DNA primase small subunit", "DNA replication complex GINS protein PSF2", "DNA replication licensing factor MCM2", "DNA replication licensing factor MCM3", "DNA replication licensing factor MCM4", "DNA replication licensing factor MCM5", "DNA replication licensing factor MCM6", "DNA replication licensing factor MCM7", "DNA topoisomerase", "DNA topoisomerase 1", "DNA-3-methyladenine glycosylase", "DNA-directed DNA polymerase", "DNA-directed RNA polymerase", "DNA-directed RNA polymerase I subunit RPA1", "DNA-directed RNA polymerase I subunit RPA2", "DNA-directed RNA polymerase I subunit RPA43", "DNA-directed RNA polymerase II subunit RPB1", "DNA-directed RNA polymerase II subunit RPB2", "DNA-directed RNA polymerase II subunit RPB3", "DNA-directed RNA polymerase II subunit RPB4", "DNA-directed RNA polymerase II subunit RPB7", "DNA-directed RNA polymerase III subunit RPC1", "DNA-directed RNA polymerase III subunit RPC3", "DNA-directed RNA polymerase III subunit RPC5", "DNA-directed RNA polymerase, mitochondrial", "DNA-directed RNA polymerases I and III subunit RPAC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC1", "DNA-directed RNA polymerases I, II, and III subunit RPABC5", "DNAPK subfamily", "DYRK family", "Damaged DNA-binding protein", "Deacetylase", "Deaminase", "Death-inducer obliterator 1", "Decarboxylase", "Dedicator of cytokinesis protein 7", "Dehydratase", "Dehydrogenase", "Delta(14)-sterol reductase", "Delta(24)-sterol reductase", "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial", "Delta-1-pyrroline-5-carboxylate synthase", "Density-regulated protein", "Deoxycytidine kinase", "Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial", "Derlin-1", "Desmocollin-3", "Desmoglein-2", "Desmoplakin", "Digestive organ expansion factor homolog", "Dihydrofolate reductase", "Dihydrolipoyl dehydrogenase, mitochondrial", "Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial", "Dihydropteridine reductase", "Dihydropyrimidinase-related protein 2", "Dihydropyrimidinase-related protein 5", "Dipeptidyl peptidase 1", "Dipeptidyl peptidase 3", "Dipeptidyl peptidase 9", "Diphthine methyl ester synthase", "Disks large-associated protein 5", "Dna-dependent protein kinase catalytic subunit", "Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase", "Dolichol-phosphate mannosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3A", "Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B", "Dolichyldiphosphatase 1", "Double-stranded RNA-specific adenosine deaminase", "Drebrin", "Drebrin-like protein", "Dual specificity mitogen-activated protein kinase kinase 1", "Dual specificity protein kinase ttk", "Dynactin subunit 1", "Dynactin subunit 2", "Dynamin-1-like protein", "Dynamin-2", "Dynamin-3", "Dynamin-like 120 kDa protein, mitochondrial", "Dynein light chain 1, cytoplasmic", "Dynein light chain 2, cytoplasmic", "Dystonin", "E3 SUMO-protein ligase RanBP2", "E3 ubiquitin-protein ligase ARIH1", "E3 ubiquitin-protein ligase ARIH2", "E3 ubiquitin-protein ligase HUWE1", "E3 ubiquitin-protein ligase Itchy homolog", "E3 ubiquitin-protein ligase MARCH5", "E3 ubiquitin-protein ligase RBBP6", "E3 ubiquitin-protein ligase RNF14", "E3 ubiquitin-protein ligase ZNF598", "E3 ubiquitin-protein ligase listerin", "EF-hand domain-containing protein D1", "EF-hand domain-containing protein D2", "EH domain-containing protein 1", "EH domain-containing protein 4", "ELKS/Rab6-interacting/CAST family member 1", "ELMO domain-containing protein 2", "ER lumen protein-retaining receptor 1", "ER membrane protein complex subunit 2", "ERK subfamily", "ERO1-like protein alpha", "ERO1-like protein beta", "Early endosome antigen 1", "Electron transfer flavoprotein subunit alpha, mitochondrial", "Electron transfer flavoprotein subunit beta", "Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial", "Elongation factor 1-alpha 2", "Elongation factor 1-beta", "Elongation factor 1-delta", "Elongation factor 2", "Elongation factor Ts, mitochondrial", "Elongation factor Tu, mitochondrial", "Elongation factor-like GTPase 1", "Elongator complex protein 1", "Elongator complex protein 3", "Elongin-B", "Elongin-C", "Endodeoxyribonuclease", "Endonuclease III-like protein 1", "Endoplasmic reticulum aminopeptidase 1", "Endoplasmic reticulum aminopeptidase 2", "Endoplasmic reticulum metallopeptidase 1", "Endoplasmic reticulum protein SC65", "Endoplasmic reticulum resident protein 29", "Endoplasmin", "Endoribonuclease", "Endoribonuclease Dicer", "Endothelial protein C receptor", "Endothelin-converting enzyme 1", "Engulfment and cell motility protein 2", "Enhancer of mRNA-decapping protein 4", "Enhancer of rudimentary homolog", "Enoyl-CoA delta isomerase 1, mitochondrial", "Enoyl-CoA delta isomerase 2, mitochondrial", "Enoyl-CoA hydratase, mitochondrial", "Enzyme", "Enzyme modulator", "Eph family", "Ephrin type-a receptor 7", "Epidermal growth factor receptor substrate 15", "Epidermal growth factor receptor substrate 15-like 1", "Epigenetic regulator", "Epimerase family protein SDR39U1", "Epimerase/racemase", "Epiplakin", "Equilibrative nucleoside transporter 1", "Eraser", "Erythrocyte band 7 integral membrane protein", "Esterase", "Ethanolamine kinase 1", "Ethylmalonyl-CoA decarboxylase", "Eukaryotic peptide chain release factor GTP-binding subunit ERF3A", "Eukaryotic peptide chain release factor subunit 1", "Eukaryotic translation initiation factor 2 subunit 1", "Eukaryotic translation initiation factor 2 subunit 2", "Eukaryotic translation initiation factor 2 subunit 3", "Eukaryotic translation initiation factor 2A", "Eukaryotic translation initiation factor 2D", "Eukaryotic translation initiation factor 3 subunit A", "Eukaryotic translation initiation factor 3 subunit B", "Eukaryotic translation initiation factor 3 subunit D", "Eukaryotic translation initiation factor 3 subunit E", "Eukaryotic translation initiation factor 3 subunit F", "Eukaryotic translation initiation factor 3 subunit H", "Eukaryotic translation initiation factor 3 subunit I", "Eukaryotic translation initiation factor 3 subunit J", "Eukaryotic translation initiation factor 3 subunit L", "Eukaryotic translation initiation factor 4 gamma 1", "Eukaryotic translation initiation factor 4 gamma 2", "Eukaryotic translation initiation factor 4 gamma 3", "Eukaryotic translation initiation factor 4B", "Eukaryotic translation initiation factor 4E", "Eukaryotic translation initiation factor 4E type 2", "Eukaryotic translation initiation factor 4H", "Eukaryotic translation initiation factor 5", "Eukaryotic translation initiation factor 5A-1", "Eukaryotic translation initiation factor 5B", "Eukaryotic translation initiation factor 6", "Exocyst complex component 1", "Exocyst complex component 3", "Exocyst complex component 4", "Exocyst complex component 5", "Exocyst complex component 6", "Exocyst complex component 7", "Exodeoxyribonuclease", "Exonuclease 1", "Exoribonuclease", "Exosome complex component CSL4", "Exosome complex component MTR3", "Exosome complex component RRP4", "Exosome complex component RRP40", "Exosome complex component RRP41", "Exosome complex component RRP42", "Exosome complex component RRP43", "Exosome complex component RRP45", "Exosome complex component RRP46", "Exosome complex exonuclease RRP44", "Exostosin-2", "Exportin-1", "Exportin-2", "Exportin-4", "Exportin-5", "Exportin-7", "Exportin-T", "Extracellular matrix glycoprotein", "Extracellular matrix structural protein", "Extracellular structure", "Ezrin", "F-actin-capping protein subunit alpha-1", "F-actin-capping protein subunit alpha-2", "F-actin-capping protein subunit beta", "F-type ATPase", "F-type and V-type ATPases", "FACT complex subunit SPT16", "FAD-dependent oxidoreductase domain-containing protein 1", "FRAP subfamily", "FRAY subfamily", "Fanconi anemia group J protein", "Far upstream element-binding protein 1", "Far upstream element-binding protein 2", "Far upstream element-binding protein 3", "Farnesyl pyrophosphate synthase", "Fascin", "Fatty acid synthase", "Ferrochelatase, mitochondrial", "Fidgetin-like protein 1", "Flap endonuclease 1", "Folate transporter 1", "Fragile X mental retardation syndrome-related protein 1", "Fragile X mental retardation syndrome-related protein 2", "Fumarate hydratase, mitochondrial", "G patch domain-containing protein 4", "G-patch domain and KOW motifs-containing protein", "G-protein", "G-protein coupled receptor", "G-protein modulator", "G-rich sequence factor 1", "GA-binding protein alpha chain", "GC-rich sequence DNA-binding factor 2", "GDP-L-fucose synthase", "GDP-fucose protein O-fucosyltransferase 2", "GDP-mannose 4,6 dehydratase", "GEK subfamily", "GMP synthase [glutamine-hydrolyzing]", "GPI-anchor transamidase", "GPN-loop GTPase 1", "GSK family", "GSK subfamily", "GTP-binding nuclear protein Ran", "GTP-binding protein 1", "GTP-binding protein Rheb", "GTPase Era, mitochondrial", "GTPase-activating protein and VPS9 domain-containing protein 1", "Galactokinase", "Galactosidase", "Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 3", "Galectin-3", "Gamma-adducin", "Gamma-aminobutyric acid receptor-associated protein-like 2", "Gamma-enolase", "Gamma-glutamyl hydrolase", "Gamma-taxilin", "Gamma-tubulin complex component 2", "Gamma-tubulin complex component 3", "Ganglioside GM2 activator", "Gap junction-forming innexin (innexin) family", "General transcription factor 3C polypeptide 3", "General transcription factor 3C polypeptide 5", "General transcription factor IIF subunit 1", "General transcription factor IIF subunit 2", "General transcription factor IIH subunit 1", "General transcription factor IIH subunit 4", "General vesicular transport factor p115", "Geranylgeranyl transferase type-2 subunit alpha", "Geranylgeranyl transferase type-2 subunit beta", "Glia maturation factor beta", "Glucosamine-6-phosphate isomerase 1", "Glucose-6-phosphate 1-dehydrogenase", "Glucose-6-phosphate isomerase", "Glucose-induced degradation protein 8 homolog", "Glucosidase", "Glucosidase 2 subunit beta", "Glutamate--cysteine ligase catalytic subunit", "Glutamate--cysteine ligase regulatory subunit", "Glutaminase kidney isoform, mitochondrial", "Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1", "Glutamine--tRNA ligase", "Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial", "Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial", "Glutaredoxin-3", "Glutaredoxin-related protein 5, mitochondrial", "Glutathione reductase, mitochondrial", "Glutathione synthetase", "Glyceraldehyde-3-phosphate dehydrogenase", "Glycerol-3-phosphate acyltransferase 4", "Glycerol-3-phosphate dehydrogenase, mitochondrial", "Glycerol-3-phosphate phosphatase", "Glycine dehydrogenase (decarboxylating), mitochondrial", "Glycine--tRNA ligase", "Glycogen debranching enzyme", "Glycogen phosphorylase, brain form", "Glycogen phosphorylase, liver form", "Glycogen synthase kinase-3 alpha", "Glycogen synthase kinase-3 beta", "Glycogenin-1", "Glycolipid transfer protein", "Glycosidase", "Glycosylase", "Glycosyltransferase", "Glycylpeptide N-tetradecanoyltransferase 1", "Glyoxylate reductase/hydroxypyruvate reductase", "Golgi SNAP receptor complex member 1", "Golgi SNAP receptor complex member 2", "Golgi pH regulator family", "Golgi ph regulator b", "Golgin subfamily A member 2", "Group XV phospholipase A2", "Growth factor", "GrpE protein homolog 1, mitochondrial", "Gtp:amp phosphotransferase ak3, mitochondrial", "Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-12", "Guanine nucleotide-binding protein G(i) subunit alpha-1", "Guanine nucleotide-binding protein G(i) subunit alpha-2", "Guanine nucleotide-binding protein G(k) subunit alpha", "Guanine nucleotide-binding protein G(o) subunit alpha", "Guanine nucleotide-binding protein subunit alpha-11", "Guanine nucleotide-binding protein subunit alpha-13", "Guanyl-nucleotide exchange factor", "H(+)/Cl(-) exchange transporter 3", "H(+)/Cl(-) exchange transporter 7", "H/ACA ribonucleoprotein complex subunit 1", "H/ACA ribonucleoprotein complex subunit 2", "H/ACA ribonucleoprotein complex subunit 3", "HBS1-like protein", "HDAC class I", "HDAC class III", "HEAT repeat-containing protein 1", "HEAT repeat-containing protein 6", "HIV Tat-specific factor 1", "Haloacid dehalogenase-like hydrolase domain-containing 5", "Haloacid dehalogenase-like hydrolase domain-containing protein 2", "Heat shock protein 75 kDa, mitochondrial", "Heat shock protein HSP 90-alpha", "Heat shock protein HSP 90-beta", "Helicase", "Helix-turn-helix transcription factor", "Hepatoma-derived growth factor", "Hepatoma-derived growth factor-related protein 2", "Hepatoma-derived growth factor-related protein 3", "Heterogeneous nuclear ribonucleoprotein F", "Heterogeneous nuclear ribonucleoprotein H", "Heterogeneous nuclear ribonucleoprotein H2", "Heterogeneous nuclear ribonucleoprotein H3", "Heterogeneous nuclear ribonucleoprotein K", "Heterogeneous nuclear ribonucleoprotein M", "Heterogeneous nuclear ribonucleoprotein Q", "Heterogeneous nuclear ribonucleoprotein R", "Heterotrimeric G-protein", "Hexokinase family", "Hexokinase-1", "Hexokinase-2", "High affinity cationic amino acid transporter 1", "High mobility group protein B1", "High mobility group protein B2", "High mobility group protein B3", "High mobility group protein HMG-I/HMG-Y", "Histidine triad nucleotide-binding protein 2, mitochondrial", "Histidine triad nucleotide-binding protein 3", "Histone", "Histone H1.0", "Histone H1.2", "Histone H1.3", "Histone H1.4", "Histone H1x", "Histone H2AX", "Histone H4", "Histone acetyltransferase KAT7", "Histone acetyltransferase type B catalytic subunit", "Histone deacetylase", "Histone deacetylase 1", "Histone deacetylase 2", "Histone deacetylase complex subunit SAP18", "Histone deacetylase complex subunit SAP30", "Histone-arginine methyltransferase CARM1", "Histone-lysine N-methyltransferase EZH2", "Histone-lysine N-methyltransferase NSD2", "Histone-lysine N-methyltransferase NSD3", "Histone-lysine N-methyltransferase SMYD3", "Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific", "Hormone", "Hsp90 co-chaperone Cdc37", "Hsp90 family chaperone", "Huntingtin-interacting protein 1", "Huntingtin-interacting protein 1-related protein", "Hydrolase", "Hydroxylase", "Hydroxymethylglutaryl-CoA lyase, mitochondrial", "Hypoxanthine-guanine phosphoribosyltransferase", "IKK family", "ILK subfamily", "ITPK1 family", "Immune response", "Immunoglobulin fold transcription factor", "Immunoglobulin receptor superfamily", "Immunoglobulin superfamily cell adhesion molecule", "Immunoglobulin-binding protein 1", "Importin subunit alpha-1", "Importin subunit alpha-4", "Importin subunit alpha-5", "Importin subunit alpha-7", "Importin subunit beta-1", "Importin-11", "Importin-4", "Importin-5", "Importin-7", "Importin-8", "Importin-9", "Inactive tyrosine-protein kinase 7", "Induced myeloid leukemia cell differentiation protein Mcl-1", "Inhibitor of nuclear factor kappa-b kinase subunit alpha", "Inhibitor of nuclear factor kappa-b kinase subunit beta", "Inorganic pyrophosphatase", "Inorganic pyrophosphatase 2, mitochondrial", "Inosine triphosphate pyrophosphatase", "Inosine-5'-monophosphate dehydrogenase 1", "Inosine-5'-monophosphate dehydrogenase 2", "Inositol monophosphatase 3", "Inositol polyphosphate 5-phosphatase OCRL-1", "Inositol-tetrakisphosphate 1-kinase", "Insulin-degrading enzyme", "Insulin-like growth factor 2 mRNA-binding protein 1", "Insulin-like growth factor 2 mRNA-binding protein 2", "Insulin-like growth factor 2 mRNA-binding protein 3", "Integrator complex subunit 11", "Integrin beta-1", "Integrin-linked kinase-associated serine/threonine phosphatase 2C", "Integrin-linked protein kinase", "Interferon-induced, double-stranded rna-activated protein kinase", "Interferon-inducible double-stranded rna-dependent protein kinase activator a", "Interleukin enhancer-binding factor 3", "Intermediate filament", "Intermediate filament binding protein", "Intersectin-2", "Intracellular calcium-sensing protein", "Intracellular chloride channel (clic) family", "Intracellular chloride channel (icc) family", "Ion channel", "Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial", "Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial", "Isoleucine--tRNA ligase, cytoplasmic", "Isoleucine--tRNA ligase, mitochondrial", "Isomerase", "Isopentenyl-diphosphate Delta-isomerase 1", "Isovaleryl-CoA dehydrogenase, mitochondrial", "Jumonji domain-containing", "KH domain-containing, RNA-binding, signal transduction-associated protein 1", "KRAB box transcription factor", "KRR1 small subunit processome component homolog", "Katanin p60 ATPase-containing subunit A1", "Ketosamine-3-kinase", "Kinase", "Kinase activator", "Kinase inhibitor", "Kinase modulator", "Kinesin-1 heavy chain", "Kinesin-like protein KIF11", "Kinesin-like protein KIF18B", "Kinesin-like protein KIF20A", "Kinesin-like protein KIF20B", "Kinesin-like protein KIF22", "Kinesin-like protein KIF23", "Kinesin-like protein KIF2A", "Kinesin-like protein KIF2C", "Kinesin-like protein KIF3A", "Kinesin-like protein KIFC1", "Kynurenine--oxoglutarate transaminase 3", "L-2-hydroxyglutarate dehydrogenase, mitochondrial", "L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase", "L-lactate dehydrogenase A chain", "L-lactate dehydrogenase B chain", "LIM domain and actin-binding protein 1", "LU7TM family", "La-related protein 1", "La-related protein 4", "La-related protein 4B", "La-related protein 7", "Lamin-B receptor", "Lamina-associated polypeptide 2, isoform alpha", "Laminin subunit beta-1", "Laminin subunit gamma-1", "Lanosterol 14-alpha demethylase", "Large neutral amino acids transporter small subunit 1", "Large proline-rich protein BAG6", "Lathosterol oxidase", "Legumain", "Lethal(2) giant larvae protein homolog 1", "Leucine-rich repeat and WD repeat-containing protein 1", "Leucine-rich repeat-containing protein 47", "Leucyl-cystinyl aminopeptidase", "Leukocyte elastase inhibitor", "Ligase", "Lipase", "Lipid kinase", "Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial", "Lon protease homolog, mitochondrial", "Long-chain fatty acid transport protein 4", "Long-chain-fatty-acid--CoA ligase 1", "Long-chain-fatty-acid--CoA ligase 3", "Long-chain-fatty-acid--CoA ligase 4", "Long-chain-fatty-acid--CoA ligase 6", "Lupus La protein", "Lyase", "Lymphokine-activated killer t-cell-originated protein kinase", "Lysine demethylase", "Lysine--tRNA ligase", "Lysine-specific demethylase", "Lysine-specific demethylase 3B", "Lysine-specific histone demethylase 1A", "Lysine-specific histone demethylase 1B", "Lysophosphatidic acid phosphatase type 6", "Lysophosphatidylcholine acyltransferase 1", "Lysophospholipid acyltransferase 7", "Lysosomal Pro-X carboxypeptidase", "Lysosomal acid lipase/cholesteryl ester hydrolase", "Lysosomal acid phosphatase", "Lysosomal alpha-glucosidase", "Lysosomal protective protein", "Lysosomal thioesterase PPT2", "Lysosomal-associated transmembrane protein 4A", "Lysosome membrane protein 2", "Lysosome-associated membrane glycoprotein 1", "Lysosome-associated membrane glycoprotein 2", "MAGUK p55 subfamily member 2", "MAGUK p55 subfamily member 5", "MAGUK p55 subfamily member 6", "MAGUK p55 subfamily member 7", "MAP7 domain-containing protein 1", "MAPK family", "MARK subfamily", "MAST family", "MCU family", "MFS-type transporter SLC18B1", "MHC class II regulatory factor RFX1", "MLK family", "MMS19 nucleotide excision repair protein homolog", "MOB-like protein phocein", "MST subfamily", "Magnesium transporter protein 1", "Major facilitator superfamily domain-containing protein 3", "Major histocompatibility complex antigen", "Malate dehydrogenase, cytoplasmic", "Malate dehydrogenase, mitochondrial", "Malignant T-cell-amplified sequence 1", "Mannose-6-phosphate isomerase", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA", "Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB", "Mediator of RNA polymerase II transcription subunit 14", "Mediator of RNA polymerase II transcription subunit 21", "Mediator of RNA polymerase II transcription subunit 25", "Medium-chain specific acyl-CoA dehydrogenase, mitochondrial", "Melanoma inhibitory activity protein 2", "Melanoma-associated antigen D2", "Membralin", "Membrane trafficking regulatory protein", "Membrane-associated progesterone receptor component 1", "Membrane-associated progesterone receptor component 2", "Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase", "Metal-response element-binding transcription factor 2", "Metalloprotease", "Metastasis-associated protein MTA1", "Metastasis-associated protein MTA2", "Methionine aminopeptidase 1", "Methionine--tRNA ligase, mitochondrial", "Methyl-CpG-binding domain", "Methyl-CpG-binding protein 2", "Methyl-lysine/arginine binding protein", "Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial", "Methylcrotonoyl-CoA carboxylase subunit alpha, mitochondrial", "Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial", "Methylmalonyl-CoA mutase, mitochondrial", "Methylosome subunit pICln", "Methylsterol monooxygenase 1", "Methyltransferase", "Methyltransferase-like protein 7B", "Microfibrillar-associated protein 1", "Microsomal glutathione S-transferase 2", "Microsomal glutathione S-transferase 3", "Microtubule binding motor protein", "Microtubule family cytoskeletal protein", "Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5", "Microtubule-associated protein 1A", "Microtubule-associated protein 1B", "Microtubule-associated protein 1S", "Microtubule-associated protein RP/EB family member 1", "Microtubule-associated protein RP/EB family member 2", "Minor histocompatibility antigen H13", "Miscellaneous SLC25 mitochondrial transporters", "Mitochondrial 2-oxodicarboxylate carrier", "Mitochondrial 2-oxoglutarate/malate carrier protein", "Mitochondrial Rho GTPase 1", "Mitochondrial Rho GTPase 2", "Mitochondrial amino acid transporter subfamily", "Mitochondrial cardiolipin hydrolase", "Mitochondrial carnitine/acylcarnitine carrier protein", "Mitochondrial carrier homolog 1", "Mitochondrial carrier homolog 2", "Mitochondrial coenzyme A transporter SLC25A42", "Mitochondrial di- and tri-carboxylic acid transporter subfamily", "Mitochondrial dicarboxylate carrier", "Mitochondrial folate transporter/carrier", "Mitochondrial import inner membrane translocase subunit Tim10 B", "Mitochondrial import inner membrane translocase subunit Tim22", "Mitochondrial import receptor subunit TOM20 homolog", "Mitochondrial import receptor subunit TOM40 homolog", "Mitochondrial inner membrane protein OXA1L", "Mitochondrial intermediate peptidase", "Mitochondrial nucleotide transporter subfamily", "Mitochondrial ornithine transporter 1", "Mitochondrial phosphate transporters", "Mitochondrial proton/calcium exchanger protein", "Mitochondrial pyruvate carrier 2", "Mitochondrial thiamine pyrophosphate carrier", "Mitochondrial-processing peptidase subunit alpha", "Mitochondrial-processing peptidase subunit beta", "Mitofusin-2", "Mitogen-activated protein kinase 1", "Mitogen-activated protein kinase 14", "Mitogen-activated protein kinase 3", "Mitogen-activated protein kinase kinase kinase 7", "Mitotic checkpoint protein BUB3", "Mitotic checkpoint serine/threonine-protein kinase bub1 beta", "Moesin", "Molybdate-anion transporter", "Monoacylglycerol lipase ABHD12", "Monoacylglycerol lipase ABHD6", "Monocarboxylate transporter 1", "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "Mortality factor 4-like protein 1", "Mortality factor 4-like protein 2", "Mpv17-like protein 2", "Multidrug resistance protein 1", "Multidrug resistance-associated protein 1", "Multidrug resistance-associated protein 4", "Multifunctional protein ADE2", "Multiple coagulation factor deficiency protein 2", "Mutase", "Myb-binding protein 1A", "Myelin expression factor 2", "Myosin light polypeptide 6", "Myosin phosphatase Rho-interacting protein", "N-acetyl-D-glucosamine kinase", "N-acetylgalactosamine-6-sulfatase", "N-acetylgalactosaminyltransferase 7", "N-acetylglucosamine-6-sulfatase", "N-acylneuraminate cytidylyltransferase", "N-alpha-acetyltransferase 10", "N-alpha-acetyltransferase 15, NatA auxiliary subunit", "N-alpha-acetyltransferase 16, NatA auxiliary subunit", "N-alpha-acetyltransferase 50", "N-terminal Xaa-Pro-Lys N-methyltransferase 1", "N-terminal kinase-like protein", "NAD kinase 2, mitochondrial", "NAD(P) transhydrogenase, mitochondrial", "NAD-dependent malic enzyme, mitochondrial", "NAD-dependent protein deacetylase sirtuin-1", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6", "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial", "NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial", "NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial", "NADH-ubiquinone oxidoreductase chain 1", "NADH-ubiquinone oxidoreductase chain 5", "NADP-dependent malic enzyme", "NADPH:adrenodoxin oxidoreductase, mitochondrial", "NAK family", "NEDD8-activating enzyme E1 catalytic subunit", "NEDD8-activating enzyme E1 regulatory subunit", "NEK family", "NF-kappa-B-repressing factor", "NHP2-like protein 1", "NRBP family", "NSFL1 cofactor p47", "Na+/K+-ATPases", "Nardilysin", "Neuferricin", "Neurolysin, mitochondrial", "Neuronal-specific septin-3", "Neuropathy target esterase", "Neuroplastin", "Neutral alpha-glucosidase AB", "Neutral amino acid transporter B(0)", "Neutral cholesterol ester hydrolase 1", "Nibrin", "Nicotinamide phosphoribosyltransferase", "Nipped-B-like protein", "Nischarin", "Non-POU domain-containing octamer-binding protein", "Non-histone chromosomal protein HMG-14", "Non-histone chromosomal protein HMG-17", "Non-motor actin binding protein", "Non-motor microtubule binding protein", "Non-protein kinase", "Non-structural maintenance of chromosomes element 3 homolog", "Nuclear RNA export factor 1", "Nuclear cap-binding protein subunit 1", "Nuclear migration protein nudC", "Nuclear pore complex protein Nup107", "Nuclear pore complex protein Nup153", "Nuclear pore complex protein Nup160", "Nuclear pore complex protein Nup214", "Nuclear pore complex protein Nup85", "Nuclear pore complex protein Nup88", "Nuclear pore complex protein Nup93", "Nuclear pore complex protein Nup98-Nup96", "Nuclear pore glycoprotein p62", "Nuclear pore membrane glycoprotein 210", "Nuclear receptor coactivator 5", "Nuclear receptor-binding protein", "Nuclease", "Nucleic acid binding", "Nucleobindin-1", "Nucleobindin-2", "Nucleolar MIF4G domain-containing protein 1", "Nucleolar complex protein 4 homolog", "Nucleolar protein 14", "Nucleolar protein 56", "Nucleolar protein 58", "Nucleolar protein 6", "Nucleolar protein 9", "Nucleolin", "Nucleophosmin", "Nucleoporin Nup37", "Nucleoporin SEH1", "Nucleoporin p54", "Nucleoside diphosphate kinase A", "Nucleoside diphosphate kinase B", "Nucleoside kinase", "Nucleosome assembly protein 1-like 1", "Nucleosome assembly protein 1-like 4", "Nucleotide kinase", "Nucleotide phosphatase", "Nucleotidyltransferase", "NudC domain-containing protein 2", "NudC domain-containing protein 3", "OCIA domain-containing protein 1", "Obg-like ATPase 1", "Occludin", "Origin recognition complex subunit 2", "Origin recognition complex subunit 3", "Origin recognition complex subunit 5", "Ornithine aminotransferase, mitochondrial", "Other 7TM proteins", "Other group", "Other small molecule kinase", "Oxidase", "Oxidoreductase", "Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial", "Oxygenase", "P-type ATPases", "P38 subfamily", "P53-like transcription factor", "PAKA subfamily", "PAKB subfamily", "PAX3- and PAX7-binding protein 1", "PC4 and SFRS1-interacting protein", "PDHK family", "PDZ and LIM domain protein 1", "PDZ and LIM domain protein 5", "PDZ and LIM domain protein 7", "PDZ domain-containing protein 11", "PDZ domain-containing protein GIPC1", "PEK family", "PH-interacting protein", "PHD finger protein 10", "PHD finger protein 14", "PHD finger protein 3", "PHD finger protein 6", "PI3/PI4 kinase family", "PIKK family", "PITSLRE subfamily", "PKA family", "PKC delta subfamily", "PKC family", "PKN family", "PLK family", "PMS1 protein homolog 1", "Paired amphipathic helix protein Sin3a", "Palmitoyl-protein thioesterase 1", "Pannexin-1", "Pantothenate kinase 4", "Paraspeckle component 1", "Pentatricopeptide repeat-containing protein 1, mitochondrial", "Peptidyl-prolyl cis-trans isomerase FKBP1A", "Peptidyl-prolyl cis-trans isomerase FKBP4", "Peptidyl-prolyl cis-trans isomerase FKBP5", "Peptidyl-prolyl cis-trans isomerase-like 1", "Peptidyl-prolyl cis-trans isomerase-like 3", "Peptidylprolyl isomerase domain and WD repeat-containing protein 1", "Perilipin-3", "Periodic tryptophan protein 1 homolog", "Peripheral plasma membrane protein cask", "Peroxidase", "Peroxiredoxin-2", "Peroxiredoxin-4", "Peroxiredoxin-6", "Peroxisomal NADH pyrophosphatase NUDT12", "Peroxisomal acyl-coenzyme A oxidase 1", "Peroxisomal acyl-coenzyme A oxidase 3", "Peroxisomal biogenesis factor 19", "Peroxisomal carnitine O-octanoyltransferase", "Peroxisomal leader peptide-processing protease", "Peroxisomal membrane protein 2", "Peroxisomal membrane protein PEX14", "Peroxisomal membrane protein PMP34", "Peroxisomal targeting signal 1 receptor", "Peroxisomal trans-2-enoyl-CoA reductase", "Pescadillo homolog", "Phenylalanine--tRNA ligase beta subunit", "Phosphatase", "Phosphatase activator", "Phosphatase inhibitor", "Phosphatase modulator", "Phosphate carrier protein, mitochondrial", "Phosphatidylethanolamine-binding protein 1", "Phosphatidylinositol 4-kinase alpha", "Phosphatidylinositol 4-kinase beta", "Phosphatidylinositol 4-kinase type 2-alpha", "Phosphatidylinositol 4-phosphate 3-kinase c2 domain-containing subunit alpha", "Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma", "Phosphatidylinositol transfer protein alpha isoform", "Phosphatidylinositol transfer protein beta isoform", "Phosphatidylinositol-binding clathrin assembly protein", "Phosphatidylserine synthase 1", "Phosphatidylserine synthase 2", "Phosphodiesterase", "Phosphoenolpyruvate carboxykinase [GTP] family", "Phosphoenolpyruvate carboxykinase [gtp], mitochondrial", "Phosphofructokinase type A (PFKA) family", "Phosphoglycerate kinase 1", "Phosphoglycerate kinase family", "Phosphoinositide 3-kinase (PI3K) family", "Phosphoinositide 3-kinase regulatory subunit 4", "Phospholipase", "Phospholipase A-2-activating protein", "Phosphoribosyl pyrophosphate synthase-associated protein 1", "Phosphoribosyl pyrophosphate synthase-associated protein 2", "Phosphorylase", "Phosphorylase b kinase regulatory chain family", "Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform", "Phosphorylated adapter RNA export protein", "Pirin", "Plasma membrane calcium-transporting ATPase 1", "Plasma membrane calcium-transporting ATPase 4", "Plasminogen activator inhibitor 1 RNA-binding protein", "Plastin-1", "Plastin-3", "Plectin", "Pogo transposable element with ZNF domain", "Poly(A) RNA polymerase, mitochondrial", "Poly(A) polymerase alpha", "Poly(A)-specific ribonuclease PARN", "Poly(ADP-ribose) glycohydrolase", "Poly(rC)-binding protein 1", "Poly(rC)-binding protein 2", "Polycomb protein SUZ12", "Polyglutamine-binding protein 1", "Polymerase", "Polymerase delta-interacting protein 3", "Polypeptide N-acetylgalactosaminyltransferase 1", "Polypeptide N-acetylgalactosaminyltransferase 2", "Polypeptide N-acetylgalactosaminyltransferase 4", "Polyribonucleotide nucleotidyltransferase 1, mitochondrial", "Porphobilinogen deaminase", "Pre-mRNA-processing factor 6", "Pre-mRNA-processing-splicing factor 8", "Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15", "Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16", "Pre-mRNA-splicing factor CWC22 homolog", "Pre-mRNA-splicing factor RBM22", "Pre-mRNA-splicing factor SPF27", "Pre-mRNA-splicing factor SYF1", "Prefoldin subunit 2", "Prefoldin subunit 3", "Prefoldin subunit 5", "Presenilins-associated rhomboid-like protein, mitochondrial", "Presequence protease, mitochondrial", "Primase", "Probable 18S rRNA (guanine-N(7))-methyltransferase", "Probable ATP-dependent RNA helicase DHX37", "Probable ATP-dependent RNA helicase DHX40", "Probable RNA-binding protein 19", "Probable U3 small nucleolar RNA-associated protein 11", "Probable global transcription activator SNF2L1", "Probable glutamate--tRNA ligase, mitochondrial", "Probable glutathione peroxidase 8", "Probable leucine--tRNA ligase, mitochondrial", "Probable ribosome biogenesis protein RLP24", "Probable serine carboxypeptidase CPVL", "Probable tRNA pseudouridine synthase 1", "Procollagen galactosyltransferase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1", "Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2", "Programmed cell death 6-interacting protein", "Programmed cell death protein 4", "Programmed cell death protein 5", "Prolactin regulatory element-binding protein", "Proliferating cell nuclear antigen", "Prolyl 3-hydroxylase 1", "Prolyl endopeptidase", "Propionyl-CoA carboxylase alpha chain, mitochondrial", "Propionyl-CoA carboxylase beta chain, mitochondrial", "Prostaglandin E synthase 2", "Prostaglandin E synthase 3", "Prostaglandin reductase 1", "Prostaglandin reductase 2", "Prostaglandin reductase 3", "Protease", "Protease inhibitor", "Proteasome inhibitor PI31 subunit", "Protein AATF", "Protein BUD31 homolog", "Protein CMSS1", "Protein DDI1 homolog 2", "Protein ERGIC-53", "Protein FAM177A1", "Protein FRG1", "Protein Hook homolog 1", "Protein Hook homolog 2", "Protein Hook homolog 3", "Protein LSM14 homolog B", "Protein Mpv17", "Protein NDRG3", "Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2", "Protein PAT1 homolog 1", "Protein PRRC2A", "Protein PRRC2C", "Protein RRP5 homolog", "Protein Red", "Protein S100-A10", "Protein S100-A11", "Protein SCAF8", "Protein SCO1 homolog, mitochondrial", "Protein SCO2 homolog, mitochondrial", "Protein SEC13 homolog", "Protein SET", "Protein SYS1 homolog", "Protein Wiz", "Protein angel homolog 1", "Protein arginine N-methyltransferase 1", "Protein arginine N-methyltransferase 3", "Protein arginine N-methyltransferase 5", "Protein arginine methyltransferase", "Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha", "Protein gpr107", "Protein kinase", "Protein kinase C and casein kinase substrate in neurons protein 2", "Protein kinase C and casein kinase substrate in neurons protein 3", "Protein kinase c delta type", "Protein lin-28 homolog B", "Protein methyltransferase", "Protein pelota homolog", "Protein phosphatase", "Protein phosphatase 1F", "Protein phosphatase 1G", "Protein phosphatase methylesterase 1", "Protein polybromo-1", "Protein quaking", "Protein regulator of cytokinesis 1", "Protein spinster homolog 1", "Protein transport protein Sec23A", "Protein transport protein Sec23B", "Protein transport protein Sec24A", "Protein transport protein Sec24B", "Protein transport protein Sec24C", "Protein transport protein Sec31A", "Protein transport protein Sec61 subunit alpha isoform 1", "Protein tweety homolog 3", "Protein unc-119 homolog A", "Protein unc-119 homolog B", "Protein-L-isoaspartate(D-aspartate) O-methyltransferase", "Protein/nucleic acid deglycase DJ-1", "Pseudouridine-5'-phosphatase", "Pterin-4-alpha-carbinolamine dehydratase", "Purine nucleoside phosphorylase", "Puromycin-sensitive aminopeptidase", "Putative ATP-dependent RNA helicase DHX57", "Putative oxidoreductase GLYR1", "Putative phospholipase B-like 2", "Pyridoxal kinase", "Pyridoxal phosphate phosphatase", "Pyridoxine kinase family", "Pyridoxine-5'-phosphate oxidase", "Pyrophosphatase", "Pyruvate carboxylase, mitochondrial", "Pyruvate dehydrogenase phosphatase regulatory subunit, mitochondrial", "Pyruvate dehydrogenase protein X component, mitochondrial", "Pyruvate kinase pkm", "RAD53 family", "RIO family", "RIO2 subfamily", "RIPK family", "RNA 3'-terminal phosphate cyclase", "RNA 3'-terminal phosphate cyclase-like protein", "RNA binding motif protein, X-linked-like-1", "RNA binding protein", "RNA helicase", "RNA-binding motif protein, X chromosome", "RNA-binding protein 12", "RNA-binding protein 12B", "RNA-binding protein 14", "RNA-binding protein 26", "RNA-binding protein 27", "RNA-binding protein 3", "RNA-binding protein 4", "RNA-binding protein 7", "RNA-binding protein EWS", "RNA-binding protein FUS", "RNA-binding protein Nova-2", "RNA-binding protein with serine-rich domain 1", "ROCK subfamily", "RSK family", "RSK subfamily", "Rab GDP dissociation inhibitor alpha", "Rab GDP dissociation inhibitor beta", "Rab GTPase-activating protein 1", "Rab3 GTPase-activating protein non-catalytic subunit", "Rab5 GDP/GTP exchange factor", "Rac GTPase-activating protein 1", "Rac-alpha serine/threonine-protein kinase", "Rac-beta serine/threonine-protein kinase", "Radixin", "RalBP1-associated Eps domain-containing protein 1", "Ran GTPase-activating protein 1", "Ran-binding protein 3", "Ran-binding protein 6", "Ran-binding protein 9", "Ran-specific GTPase-activating protein", "Rap guanine nucleotide exchange factor 2", "Ras GTPase-activating protein-binding protein 1", "Ras GTPase-activating protein-binding protein 2", "Ras GTPase-activating-like protein IQGAP1", "Ras GTPase-activating-like protein IQGAP2", "Ras GTPase-activating-like protein IQGAP3", "Ras-related C3 botulinum toxin substrate 1", "Ras-related protein Ral-A", "Ras-related protein Rap-2b", "Reader", "Receptor", "Receptor expression-enhancing protein 2", "Receptor expression-enhancing protein 3", "Receptor expression-enhancing protein 4", "Receptor expression-enhancing protein 5", "Receptor-interacting serine/threonine-protein kinase 1", "Receptor-type tyrosine-protein phosphatase F", "Reductase", "Regulation of nuclear pre-mRNA domain-containing protein 1A", "Regulation of nuclear pre-mRNA domain-containing protein 1B", "Regulation of nuclear pre-mRNA domain-containing protein 2", "Regulator of nonsense transcripts 1", "Regulator of nonsense transcripts 2", "Remodeling and spacing factor 1", "Renin receptor", "Replication factor C subunit 2", "Replication factor C subunit 3", "Replication factor C subunit 4", "Replication factor C subunit 5", "Replication origin binding protein", "Replication protein A 70 kDa DNA-binding subunit", "Reticulocalbin-1", "Reticulocalbin-2", "Retinal dehydrogenase 2", "Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta", "Retinoid-inducible serine carboxypeptidase", "Retinol dehydrogenase 11", "Retinol dehydrogenase 14", "Rho GDP-dissociation inhibitor 1", "Rho GTPase-activating protein 10", "Rho-associated protein kinase 1", "Rho-associated protein kinase 2", "Rho-related GTP-binding protein RhoG", "Rhomboid domain-containing protein 2", "Riboflavin kinase", "Ribonuclease H2 subunit A", "Ribonuclease P protein subunit p25-like protein", "Ribonuclease P protein subunit p30", "Ribonuclease inhibitor", "Ribonucleoprotein", "Ribonucleoprotein PTB-binding 1", "Ribonucleoside-diphosphate reductase large subunit", "Ribonucleoside-diphosphate reductase subunit M2", "Ribonucleoside-diphosphate reductase subunit M2 B", "Ribose-phosphate pyrophosphokinase 1", "Ribosomal L1 domain-containing protein 1", "Ribosomal RNA small subunit methyltransferase NEP1", "Ribosomal RNA-processing protein 7 homolog A", "Ribosomal protein", "Ribosomal protein s6 kinase alpha-1", "Ribosomal protein s6 kinase alpha-3", "Ribosome biogenesis protein BOP1", "Ribosome biogenesis protein BRX1 homolog", "Ribosome biogenesis regulatory protein homolog", "Ribosome maturation protein SBDS", "Ribosome production factor 1", "Ribosome production factor 2 homolog", "Ribosome-recycling factor, mitochondrial", "S-adenosylhomocysteine hydrolase-like protein 1", "S-adenosylmethionine mitochondrial carrier protein", "S-adenosylmethionine synthase isoform type-2", "S-formylglutathione hydrolase", "S-methyl-5'-thioadenosine phosphorylase", "S-phase kinase-associated protein 1", "SAP30-binding protein", "SCY1 family", "SEC23-interacting protein", "SET domain", "SLC superfamily of solute carriers", "SLC1 family of amino acid transporters", "SLC12 family of cation-coupled chloride transporters", "SLC16 family of monocarboxylate transporters", "SLC18 family of vesicular amine transporters", "SLC19 family of vitamin transporters", "SLC2 family of hexose and sugar alcohol transporters", "SLC22 family of organic cation and anion transporters", "SLC25 family of mitochondrial transporters", "SLC27 family of fatty acid transporters", "SLC28 and SLC29 families of nucleoside transporters", "SLC29 family", "SLC3 and SLC7 families of heteromeric amino acid transporters (HATs)", "SLC3 family", "SLC30 zinc transporter family", "SLC33 acetylCoA transporter", "SLC35 family of nucleotide sugar transporters", "SLC38 family of sodium-dependent neutral amino acid transporters", "SLC39 family of metal ion transporters", "SLC4 family of bicarbonate transporters", "SLC54 Mitochondrial pyruvate carriers", "SLC55 Mitochondrial cation/proton exchangers", "SLC56 Sideroflexins", "SLC58 MagT-like magnesium transporter family", "SLC61 Molybdate transporter family", "SLC63 Sphingosine-phosphate transporters", "SLC64 Golgi Ca2+/H+ exchangers", "SLC7 family", "SLK subfamily", "SNARE protein", "SNW domain-containing protein 1", "SRPK family", "STAM-binding protein", "STE group", "STE20 family", "STE7 family", "SUMO-activating enzyme subunit 1", "SUMO-activating enzyme subunit 2", "SUN domain-containing protein 1", "SUN domain-containing protein 2", "SURP and G-patch domain-containing protein 1", "SURP and G-patch domain-containing protein 2", "SWI/SNF complex subunit SMARCC1", "SWI/SNF complex subunit SMARCC2", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1", "SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2", "Sal-like protein 2", "Sarcoplasmic/endoplasmic reticulum calcium ATPase 2", "Scavenger receptor class B member 1", "Sec1 family domain-containing protein 1", "Secretory carrier-associated membrane protein 2", "Secretory carrier-associated membrane protein 3", "Segment polarity protein dishevelled homolog DVL-2", "Selenide, water dikinase 1", "Selenocysteine lyase", "Sentrin-specific protease 3", "Septin-11", "Septin-2", "Septin-6", "Septin-7", "Septin-9", "Serine hydroxymethyltransferase, cytosolic", "Serine hydroxymethyltransferase, mitochondrial", "Serine palmitoyltransferase 1", "Serine palmitoyltransferase 2", "Serine protease", "Serine protease inhibitor", "Serine--tRNA ligase, cytoplasmic", "Serine--tRNA ligase, mitochondrial", "Serine/arginine repetitive matrix protein 1", "Serine/arginine-rich splicing factor 1", "Serine/arginine-rich splicing factor 10", "Serine/arginine-rich splicing factor 11", "Serine/arginine-rich splicing factor 2", "Serine/arginine-rich splicing factor 3", "Serine/arginine-rich splicing factor 4", "Serine/arginine-rich splicing factor 5", "Serine/arginine-rich splicing factor 6", "Serine/arginine-rich splicing factor 7", "Serine/arginine-rich splicing factor 9", "Serine/threonine-protein kinase 26", "Serine/threonine-protein kinase 4", "Serine/threonine-protein kinase chk2", "Serine/threonine-protein kinase greatwall", "Serine/threonine-protein kinase mark2", "Serine/threonine-protein kinase mrck beta", "Serine/threonine-protein kinase mtor", "Serine/threonine-protein kinase n1", "Serine/threonine-protein kinase n2", "Serine/threonine-protein kinase nek3", "Serine/threonine-protein kinase nek9", "Serine/threonine-protein kinase osr1", "Serine/threonine-protein kinase pak 2", "Serine/threonine-protein kinase pak 4", "Serine/threonine-protein kinase plk1", "Serine/threonine-protein kinase prp4 homolog", "Serine/threonine-protein kinase rio2", "Serine/threonine-protein kinase smg1", "Serine/threonine-protein kinase vrk1", "Serine/threonine-protein kinase vrk2", "Serine/threonine-protein kinase wnk1", "Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform", "Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform", "Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform", "Serine/threonine-protein phosphatase 2A activator", "Serine/threonine-protein phosphatase 4 regulatory subunit 1", "Serine/threonine-protein phosphatase 6 regulatory subunit 3", "Serine/threonine-protein phosphatase PP1-alpha catalytic subunit", "Serine/threonine-protein phosphatase PP1-beta catalytic subunit", "Serine/threonine-protein phosphatase PP1-gamma catalytic subunit", "Serpin B6", "Serpin H1", "Sex comb on midleg-like protein 2", "Sialic acid synthase", "Sideroflexin-1", "Sideroflexin-2", "Sigma intracellular receptor 2", "Signal peptidase complex catalytic subunit SEC11A", "Signal peptidase complex subunit 2", "Signal peptidase complex subunit 3", "Signal peptide peptidase-like 2A", "Signal recognition particle 14 kDa protein", "Signal recognition particle 19 kDa protein", "Signal recognition particle 54 kDa protein", "Signal recognition particle 9 kDa protein", "Signal recognition particle receptor subunit alpha", "Signal recognition particle subunit SRP68", "Signal transducer and activator of transcription 1-alpha/beta", "Signal transducer and activator of transcription 3", "Signaling", "Single-stranded DNA-binding protein, mitochondrial", "Sister chromatid cohesion protein PDS5 homolog A", "Sister chromatid cohesion protein PDS5 homolog B", "Small GTPase", "Small nuclear ribonucleoprotein E", "Small nuclear ribonucleoprotein Sm D1", "Small nuclear ribonucleoprotein Sm D2", "Small nuclear ribonucleoprotein Sm D3", "Sodium bicarbonate cotransporter 3", "Sodium-coupled neutral amino acid transporter 2", "Sodium-dependent HCO3- transporters", "Sodium/potassium-transporting ATPase subunit alpha-1", "Sodium/potassium-transporting ATPase subunit beta-1", "Sodium/potassium-transporting ATPase subunit beta-3", "Solute carrier family 12 member 2", "Solute carrier family 12 member 7", "Solute carrier family 2, facilitated glucose transporter member 1", "Solute carrier family 25 member 33", "Solute carrier family 25 member 40", "Solute carrier family 25 member 44", "Solute carrier family 35 member F2", "Sorbitol dehydrogenase", "Sortilin", "Sorting nexin-1", "Sorting nexin-2", "Spastin", "Spermatid perinuclear RNA-binding protein", "Spermidine synthase", "Sphingosine kinase 2", "Splicing factor 1", "Splicing factor 3A subunit 1", "Splicing factor 3A subunit 2", "Splicing factor 3A subunit 3", "Splicing factor 3B subunit 1", "Splicing factor 3B subunit 3", "Splicing factor 45", "Splicing factor U2AF 35 kDa subunit", "Splicing factor, arginine/serine-rich 15", "Splicing factor, proline- and glutamine-rich", "Splicing factor, suppressor of white-apricot homolog", "Squalene monooxygenase", "Squamous cell carcinoma antigen recognized by T-cells 3", "Src substrate cortactin", "Srsf protein kinase 1", "Staphylococcal nuclease domain-containing protein 1", "Ste20-like serine/threonine-protein kinase", "Sterol O-acyltransferase 1", "Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating", "Stomatin-like protein 2, mitochondrial", "Storage", "Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial", "Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial", "Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial", "Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial", "Succinate-semialdehyde dehydrogenase, mitochondrial", "Succinyl-CoA:3-ketoacid coenzyme A transferase 1, mitochondrial", "Sulfhydryl oxidase 2", "Superoxide dismutase [Mn], mitochondrial", "Surfeit locus protein 4", "Surfeit locus protein 6", "Survival motor neuron protein", "Synaptic functional regulator FMR1", "Synaptic vesicle glycoprotein 2A", "Synaptogyrin-2", "Synaptojanin-2-binding protein", "Synaptosomal-associated protein 29", "Synaptosomal-associated protein 47", "Syntaxin-10", "Syntaxin-12", "Syntaxin-18", "Syntaxin-4", "Syntaxin-5", "Syntaxin-6", "Syntaxin-7", "Syntaxin-8", "Syntaxin-binding protein 2", "Syntaxin-binding protein 3", "Syntenin-1", "System A-like transporters", "T-complex protein 1 subunit alpha", "T-complex protein 1 subunit beta", "T-complex protein 1 subunit delta", "T-complex protein 1 subunit epsilon", "T-complex protein 1 subunit eta", "T-complex protein 1 subunit gamma", "T-complex protein 1 subunit theta", "T-complex protein 1 subunit zeta", "T-complex protein 11-like protein 1", "TAIRE subfamily", "TAK1 subfamily", "TATA box-binding protein-like protein 1", "TATA-binding protein-associated factor 2N", "TATA-binding transcription factor", "TBC1 domain family member 10B", "TBC1 domain family member 13", "TBC1 domain family member 15", "TBC1 domain family member 4", "TBC1 domain family member 9B", "THO complex subunit 1", "THO complex subunit 2", "THO complex subunit 3", "THO complex subunit 4", "TK group", "TKL group", "TOPK family", "TP53-binding protein 1", "TTK family", "Tapasin", "Target of EGR1 protein 1", "Targeting protein for Xklp2", "Terminal uridylyltransferase 4", "Testin", "Testis-specific Y-encoded-like protein 1", "Tgf-beta-activated kinase 1 and map3k7-binding protein 1", "Thimet oligopeptidase", "Thioredoxin domain-containing protein 12", "Thioredoxin domain-containing protein 17", "Thioredoxin domain-containing protein 9", "Thioredoxin reductase 1, cytoplasmic", "Thioredoxin-dependent peroxide reductase, mitochondrial", "Threonine--tRNA ligase, cytoplasmic", "Threonine--tRNA ligase, mitochondrial", "Thymidine kinase family", "Thymidine kinase, cytosolic", "Thymidylate kinase", "Thymidylate kinase family", "Thymidylate synthase", "Thyroid adenoma-associated protein", "Thyroid hormone receptor-associated protein 3", "Tight junction", "Tight junction protein ZO-1", "Tight junction protein ZO-2", "Tmem38 family", "Torsin-1A", "Torsin-1B", "Trafficking protein particle complex subunit 4", "Trans-Golgi network integral membrane protein 2", "Transaminase", "Transcription activator BRG1", "Transcription cofactor", "Transcription elongation factor A protein 1", "Transcription elongation factor SPT6", "Transcription elongation regulator 1", "Transcription factor", "Transcription initiation factor IIB", "Transcription initiation factor TFIID subunit 10", "Transcriptional activator protein Pur-alpha", "Transcriptional repressor p66-alpha", "Transcriptional repressor p66-beta", "Transcriptional repressor protein YY1", "Transducin-like enhancer protein 3", "Transferase", "Transferrin receptor protein 1", "Transformer-2 protein homolog alpha", "Transformer-2 protein homolog beta", "Transgelin-2", "Transketolase", "Translation elongation factor", "Translation factor", "Translation factor GUF1, mitochondrial", "Translation initiation factor", "Translation initiation factor IF-2, mitochondrial", "Translation release factor", "Translationally-controlled tumor protein", "Translocation protein SEC63 homolog", "Translocon-associated protein subunit alpha", "Transmembrane 9 superfamily member 2", "Transmembrane 9 superfamily member 3", "Transmembrane 9 superfamily member 4", "Transmembrane emp24 domain-containing protein 10", "Transmembrane emp24 domain-containing protein 2", "Transmembrane emp24 domain-containing protein 5", "Transmembrane emp24 domain-containing protein 7", "Transmembrane emp24 domain-containing protein 9", "Transmembrane protein 115", "Transmembrane protein 165", "Transport and Golgi organization protein 1 homolog", "Transporter", "Transportin-1", "Transportin-2", "Transportin-3", "Tricarboxylate transport protein, mitochondrial", "Trifunctional enzyme subunit alpha, mitochondrial", "Trifunctional enzyme subunit beta, mitochondrial", "Trifunctional purine biosynthetic protein adenosine-3", "Trimeric intracellular cation channel type B", "Triosephosphate isomerase", "Tripeptidyl-peptidase 1", "Tripeptidyl-peptidase 2", "Trophoblast glycoprotein", "Tropomodulin-1", "Tropomodulin-3", "Tropomyosin alpha-1 chain", "Tropomyosin alpha-3 chain", "Tropomyosin alpha-4 chain", "Tryptophan--tRNA ligase, cytoplasmic", "Tubulin", "Tubulin beta chain", "Tubulin beta-2A chain", "Tubulin beta-2B chain", "Tubulin beta-4A chain", "Tubulin beta-4B chain", "Tubulin beta-6 chain", "Tubulin gamma-1 chain", "Tubulin-folding cofactor B", "Tubulin-specific chaperone A", "Tubulin-specific chaperone D", "Tubulin-specific chaperone E", "Tudor and KH domain-containing protein", "Tudor domain", "Tuftelin-interacting protein 11", "Tumor susceptibility gene 101 protein", "Twinfilin-1", "Twinfilin-2", "Twinkle protein, mitochondrial", "Type II PI4K subfamily", "Type III PI4K subfamily", "Tyrosine--tRNA ligase, cytoplasmic", "Tyrosine--tRNA ligase, mitochondrial", "Tyrosine-protein kinase csk", "U1 small nuclear ribonucleoprotein 70 kDa", "U1 small nuclear ribonucleoprotein A", "U2 small nuclear ribonucleoprotein A'", "U2 small nuclear ribonucleoprotein B''", "U2 snRNP-associated SURP motif-containing protein", "U3 small nucleolar RNA-associated protein 14 homolog A", "U3 small nucleolar RNA-associated protein 6 homolog", "U3 small nucleolar ribonucleoprotein protein IMP3", "U3 small nucleolar ribonucleoprotein protein IMP4", "U3 small nucleolar ribonucleoprotein protein MPP10", "U4/U6 small nuclear ribonucleoprotein Prp3", "U4/U6 small nuclear ribonucleoprotein Prp31", "U4/U6 small nuclear ribonucleoprotein Prp4", "U4/U6.U5 tri-snRNP-associated protein 1", "U4/U6.U5 tri-snRNP-associated protein 2", "U6 snRNA-associated Sm-like protein LSm2", "U6 snRNA-associated Sm-like protein LSm3", "U6 snRNA-associated Sm-like protein LSm5", "U6 snRNA-associated Sm-like protein LSm6", "U6 snRNA-associated Sm-like protein LSm7", "U6 snRNA-associated Sm-like protein LSm8", "UDP-glucose:glycoprotein glucosyltransferase 1", "UDP-glucuronic acid decarboxylase 1", "UMP-CMP kinase", "UV excision repair protein RAD23 homolog B", "UbiA prenyltransferase domain-containing protein 1", "Ubiquinone biosynthesis O-methyltransferase, mitochondrial", "Ubiquitin carboxyl-terminal hydrolase 1", "Ubiquitin carboxyl-terminal hydrolase 10", "Ubiquitin carboxyl-terminal hydrolase 11", "Ubiquitin carboxyl-terminal hydrolase 14", "Ubiquitin carboxyl-terminal hydrolase 15", "Ubiquitin carboxyl-terminal hydrolase 19", "Ubiquitin carboxyl-terminal hydrolase 22", "Ubiquitin carboxyl-terminal hydrolase 28", "Ubiquitin carboxyl-terminal hydrolase 38", "Ubiquitin carboxyl-terminal hydrolase 47", "Ubiquitin carboxyl-terminal hydrolase 5", "Ubiquitin carboxyl-terminal hydrolase 7", "Ubiquitin carboxyl-terminal hydrolase 8", "Ubiquitin carboxyl-terminal hydrolase isozyme L5", "Ubiquitin conjugation factor E4 A", "Ubiquitin conjugation factor E4 B", "Ubiquitin thioesterase OTUB1", "Ubiquitin-conjugating enzyme E2 L3", "Ubiquitin-like modifier-activating enzyme 1", "Ubiquitin-like modifier-activating enzyme 5", "Ubiquitin-like modifier-activating enzyme 6", "Ubiquitin-like modifier-activating enzyme ATG7", "Ubiquitin-like-conjugating enzyme ATG3", "Ubiquitin-protein ligase", "Unclassified protein", "Unconventional myosin-Ib", "Unconventional myosin-Ic", "Unconventional myosin-Id", "Unconventional myosin-VI", "Uridine kinase family", "Uridine-cytidine kinase 2", "V-type ATPase", "V-type proton ATPase 116 kDa subunit a isoform 1", "V-type proton ATPase 116 kDa subunit a isoform 2", "V-type proton ATPase catalytic subunit A", "V-type proton ATPase subunit B, brain isoform", "V-type proton ATPase subunit C 1", "V-type proton ATPase subunit D", "V-type proton ATPase subunit H", "V-type proton ATPase subunit d 1", "VIP36-like protein", "VPS15 family", "VRK family", "Vacuolar protein sorting-associated protein 18 homolog", "Vacuolar protein sorting-associated protein 26A", "Vacuolar protein sorting-associated protein 29", "Vacuolar protein sorting-associated protein 33A", "Vacuolar protein sorting-associated protein 33B", "Vacuolar protein sorting-associated protein 35", "Vacuolar protein sorting-associated protein 45", "Vacuolar protein sorting-associated protein 4A", "Vacuolar protein sorting-associated protein 4B", "Vacuolar protein sorting-associated protein 72 homolog", "Vacuole membrane protein 1", "Very long-chain specific acyl-CoA dehydrogenase, mitochondrial", "Very-long-chain enoyl-CoA reductase", "Vesicle coat protein", "Vesicle-associated membrane protein 7", "Vesicle-associated membrane protein-associated protein A", "Vesicle-associated membrane protein-associated protein B/C", "Vesicle-fusing ATPase", "Vesicular integral-membrane protein VIP36", "Vitamin K epoxide reductase complex subunit 1-like protein 1", "WASH complex subunit 5", "WD repeat and HMG-box DNA-binding protein 1", "WD repeat-containing protein 1", "WD repeat-containing protein 34", "WD repeat-containing protein 74", "WD repeat-containing protein 82", "WEE family", "WNK family", "Werner syndrome ATP-dependent helicase", "Winged helix/forkhead transcription factor", "Wiskott-Aldrich syndrome protein family member 2", "Writer", "X-ray repair cross-complementing protein 5", "X-ray repair cross-complementing protein 6", "Xaa-Pro dipeptidase", "YLP motif-containing protein 1", "YSK subfamily", "Zinc finger CCCH domain-containing protein 11A", "Zinc finger CCCH domain-containing protein 15", "Zinc finger CCHC domain-containing protein 8", "Zinc finger HIT domain-containing protein 2", "Zinc finger MYM-type protein 1", "Zinc finger MYM-type protein 2", "Zinc finger MYM-type protein 4", "Zinc finger RNA-binding protein", "Zinc finger protein 281", "Zinc finger protein 622", "Zinc finger protein 644", "Zinc finger protein ubi-d4", "Zinc finger protein-like 1", "Zinc finger transcription factor", "Zinc transporter 7", "Zinc transporter ZIP10", "Zinc transporter ZIP11", "Zinc transporter ZIP14", "Zyxin", "[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial", "[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial", "[pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial", "c-Myc-binding protein", "eIF-2-alpha kinase activator GCN1", "eukaryotic two domain clade \"e\" sub-subfamily", "m7GpppX diphosphatase", "mRNA export factor", "mRNA polyadenylation factor", "mRNA processing factor", "mRNA splicing factor", "mRNA-capping enzyme", "mRNA-decapping enzyme 1A", "mRNA-decapping enzyme 1B", "pre-mRNA 3' end processing protein WDR33", "rRNA 2'-O-methyltransferase fibrillarin", "tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A", "tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6", "tRNA (cytosine(34)-C(5))-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase", "tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4", "tRNA dimethylallyltransferase", "tRNA pseudouridine synthase A"], "available_proteins": ["AAK1", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCF1", "ABCF2", "ABCF3", "ABHD12", "ABHD6", "ABI1", "ABR", "ACAA1", "ACAA2", "ACAD10", "ACAD9", "ACADM", "ACADVL", "ACAT1", "ACAT2", "ACLY", "ACO1", "ACO2", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADPGK", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGL", "AHCY", "AHCYL1", "AIFM1", "AIMP1", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALG1", "ALG12", "ALYREF", "AMPD2", "ANAPC1", "ANGEL1", "ANO6", "ANP32A", "ANP32B", "ANP32E", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APEH", "APLP2", "APOBEC3C", "APOL2", "APP", "ARCN1", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP10", "ARHGDIA", "ARID3B", "ARIH1", "ARIH2", "ARPC3", "ARPC4", "ARRB2", "ARVCF", "AS3MT", "ASAH1", "ASNA1", "ASNS", "ATAD2", "ATAD3A", "ATAD3B", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1H", "ATPAF1", "ATPIF1", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GAT3", "B4GALT1", "B4GALT3", "BAG6", "BAIAP2", "BAK1", "BCAP31", "BCAS2", "BCAT2", "BCKDK", "BCLAF1", "BCR", "BECN1", "BLMH", "BLVRA", "BOP1", "BPNT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BUB1B", "BUB3", "BUD23", "BUD31", "BZW1", "BZW2", "CAB39", "CABIN1", "CACYBP", "CAD", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAND1", "CAND2", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CBX1", "CBX3", "CBX5", "CCAR1", "CCAR2", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD2BP2", "CDC20", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC7", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CDKN2AIP", "CEBPZ", "CENPE", "CEP170", "CEP250", "CEPT1", "CETN2", "CFAP20", "CHAF1A", "CHAF1B", "CHEK2", "CHERP", "CHKA", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTOP", "CHUK", "CIRBP", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLNS1A", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLUH", "CMAS", "CMPK1", "CMSS1", "CNDP2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNP", "COASY", "COIL", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS3", "COPS5", "COPS6", "COPS8", "COPZ1", "COQ3", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX2", "COX5A", "COX5B", "COX7A2", "COX7A2L", "COX7C", "CPOX", "CPSF1", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRNKL1", "CROT", "CRTAP", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNND1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CTTN", "CUL1", "CUL2", "CUL4B", "CUL5", "CWC22", "CYB5B", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAP3", "DARS", "DARS2", "DBN1", "DBNL", "DBT", "DCAF13", "DCAF8", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DDB1", "DDI2", "DDOST", "DDT", "DENR", "DERL1", "DHCR24", "DHCR7", "DHFR", "DHX15", "DHX29", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DICER1", "DIDO1", "DIEXF", "DIS3", "DLD", "DLGAP5", "DLST", "DNM1L", "DNM2", "DNM3", "DNMT1", "DOCK7", "DOLPP1", "DPF2", "DPH5", "DPM1", "DPP3", "DPP9", "DPYSL2", "DPYSL5", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC4", "EEA1", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHD1", "EHD4", "EIF2A", "EIF2AK2", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3H", "EIF3I", "EIF3J", "EIF3L", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELMO2", "ELMOD2", "ELOB", "ELOC", "ELP1", "ELP3", "EMC2", "EMG1", "ENO1", "ENO2", "EPHA7", "EPHX2", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERH", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ESD", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXO1", "EXOC1", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOSC1", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "FAHD1", "FAM177A1", "FARSB", "FASN", "FBL", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FIGNL1", "FKBP1A", "FKBP4", "FKBP5", "FMR1", "FN3KRP", "FNTA", "FOXRED1", "FRG1", "FSCN1", "FUBP1", "FUBP3", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GAK", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GCAT", "GCFC2", "GCLC", "GCLM", "GCN1", "GDI1", "GDI2", "GFPT1", "GGH", "GID8", "GINS2", "GIPC1", "GLB1", "GLDC", "GLRX3", "GLRX5", "GLS", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPDA1", "GNS", "GOLGA2", "GOSR1", "GOSR2", "GPAT4", "GPATCH4", "GPD2", "GPI", "GPKOW", "GPN1", "GPR107", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GTF2B", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF3C3", "GTF3C5", "GTPBP1", "GUF1", "GYG1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H4C1*", "HACL1", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HDAC1", "HDAC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD5", "HEATR1", "HEATR6", "HEXA", "HEXB", "HIBADH", "HIBCH", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HM13", "HMBS", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGN1", "HMGN2", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HOOK1", "HOOK2", "HOOK3", "HPRT1", "HSD17B10", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPE1", "HTATSF1", "HUWE1", "IARS", "IARS2", "IDE", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IK", "IKBKB", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPAD1", "IMPDH1", "IMPDH2", "INTS11", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQGAP1", "IQGAP2", "IQGAP3", "ITCH", "ITGB1", "ITPA", "ITPK1", "ITSN2", "IVD", "JMJD6", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELR1", "KDM1A", "KDM1B", "KDM3B", "KHDRBS1", "KHSRP", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "KYAT3", "L2HGDH", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS2", "LBR", "LDHA", "LDHB", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMAN2L", "LNPEP", "LONP1", "LPCAT1", "LRRC47", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LTN1", "M6PR", "MACF1", "MAGED2", "MAGT1", "MAN1A1", "MAN1A2", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS2", "MASTL", "MAT2A", "MBOAT7", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "ME1", "ME2", "MECP2", "MED14", "MED21", "MED25", "METAP1", "METTL1", "METTL7B", "MFAP1", "MFN2", "MFSD3", "MFSD5", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MIPEP", "MMS19", "MOB4", "MORF4L1", "MORF4L2", "MPC2", "MPG", "MPHOSPH10", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRPL1", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL38", "MRPL39", "MRPL41", "MRPL43", "MRPL44", "MRPL47", "MRPL48", "MRPL49", "MRPL9", "MRPS11", "MRPS16", "MRPS18A", "MRPS2", "MRPS24", "MRPS27", "MRPS35", "MRPS5", "MRPS7", "MRRF", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTA2", "MTAP", "MTCH1", "MTCH2", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MUT", "MYBBP1A", "MYCBP", "MYEF2", "MYL6", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA50", "NADK2", "NAE1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NARS", "NBN", "NCAPD2", "NCAPD3", "NCBP1", "NCEH1", "NCL", "NCOA5", "ND1", "ND5", "NDRG3", "NDUFA10", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA9", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS6", "NDUFS7", "NDUFS8", "NEK3", "NEK9", "NFS1", "NHP2", "NIPBL", "NISCH", "NKRF", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOC4L", "NOL6", "NOM1", "NONO", "NOP10", "NOP14", "NOP56", "NOP58", "NOP9", "NOVA2", "NPEPPS", "NPM1", "NPTN", "NRBP1", "NRDC", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSMCE3", "NSUN2", "NSUN4", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT21", "NUDT5", "NUDT9", "NUP107", "NUP153", "NUP160", "NUP210", "NUP214", "NUP37", "NUP54", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXF1", "OAT", "OCIAD1", "OCLN", "OCRL", "OLA1", "OPA1", "ORC2", "ORC3", "ORC5", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "PACSIN2", "PACSIN3", "PAICS", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARVA", "PATL1", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PDCD11", "PDCD4", "PDCD5", "PDCD6IP", "PDE12", "PDE6D", "PDHX", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDS5A", "PDS5B", "PDXK", "PDXP", "PDZD11", "PEBP1", "PECR", "PELO", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PFDN2", "PFDN5", "PFKL", "PFKM", "PFKP", "PGD", "PGK1", "PGLS", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHF10", "PHF14", "PHF3", "PHF6", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PICALM", "PIGK", "PIK3C2A", "PIK3R4", "PIP4K2C", "PIR", "PITPNA", "PITPNB", "PITRM1", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT2", "POGZ", "POLA2", "POLD2", "POLDIP3", "POLE2", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PPA1", "PPA2", "PPAT", "PPIL1", "PPIL3", "PPM1F", "PPM1G", "PPME1", "PPP1CA", "PPP1CB", "PPP1CC", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP4R1", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRC1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX6", "PREB", "PREP", "PRIM1", "PRKAA2", "PRKACA", "PRKAG1", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC2A", "PRRC2C", "PSIP1", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSMF1", "PSPC1", "PTCD1", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPRF", "PUDP", "PURA", "PUS1", "PWP1", "PXMP2", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "RAB3GAP2", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RAD23B", "RAE1", "RALA", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP2B", "RAPGEF2", "RAVER1", "RBBP6", "RBM12", "RBM12B", "RBM14", "RBM17", "RBM19", "RBM22", "RBM26", "RBM27", "RBM3", "RBM4", "RBM7", "RBMX", "RBMXL1", "RCL1", "RCN1", "RCN2", "RDH11", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIOK2", "RIPK1", "RNASEH2A", "RNF14", "RNGTT", "RNH1", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL18", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL38", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPN1", "RPN2", "RPP25L", "RPP30", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRM1", "RRM2", "RRM2B", "RRP7A", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RTCA", "S100A10", "S100A11", "SAE1", "SALL2", "SAP18", "SAP30", "SAP30BP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCPEP1", "SCYL1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC63", "SEH1L", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B3", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SHMT1", "SHMT2", "SIN3A", "SIRT1", "SKP1", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLK", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMG1", "SMN1*", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX2", "SOAT1", "SOD2", "SORD", "SORT1", "SPAG9", "SPAST", "SPCS2", "SPCS3", "SPHK2", "SPNS1", "SPPL2A", "SPTLC1", "SPTLC2", "SQLE", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP9", "SRPK1", "SRPRA", "SRRM1", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "STAG1", "STAG2", "STAMBP", "STAT1", "STAT3", "STK26", "STK4", "STOM", "STOML2", "STRBP", "STT3A", "STT3B", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "SUCLA2", "SUCLG2", "SUGP1", "SUGP2", "SUN1", "SUN2", "SUPT16H", "SUPT6H", "SURF4", "SURF6", "SUZ12", "SV2A", "SYNCRIP", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TAF10", "TAF15", "TAGLN2", "TAP1", "TAPBP", "TARS", "TARS2", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBPL1", "TCEA1", "TCERG1", "TCP1", "TCP11L1", "TDRKH", "TECR", "TES", "TFCP2", "TFIP11", "TFRC", "TGOLN2", "THADA", "THOC1", "THOC2", "THOC3", "THOP1", "THRAP3", "TIMM10B", "TIMM22", "TJP1", "TJP2", "TK1", "TKT", "TLE3", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM115", "TMEM165", "TMEM259", "TMEM38B", "TMEM97", "TMOD1", "TMOD3", "TMPO", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOMM20", "TOMM40", "TOP1", "TOR1A", "TOR1B", "TP53", "TP53BP1", "TPBG", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRAP1", "TRAPPC4", "TRIP4", "TRIT1", "TRMT6", "TRMT61A", "TROVE2", "TRUB1", "TSFM", "TSG101", "TSPYL1", "TSTA3", "TTK", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC17", "TXNDC9", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2SURP", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBE2L3", "UBE4A", "UBE4B", "UBIAD1", "UCHL5", "UCK2", "UGCG", "UGGT1", "UNC119", "UNC119B", "UPF1", "UPF2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP28", "USP38", "USP39", "USP47", "USP5", "USP7", "USP8", "UTP11", "UTP14A", "UTP6", "UXS1", "VAMP7", "VAPA", "VAPB", "VBP1", "VKORC1L1", "VMP1", "VPS18", "VPS26A", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS4B", "VPS72", "VRK1", "VRK2", "WARS", "WASF2", "WASHC5", "WDHD1", "WDR1", "WDR33", "WDR34", "WDR4", "WDR74", "WDR82", "WIZ", "WNK1", "WRN", "XAB2", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC5", "XRCC6", "YARS", "YARS2", "YLPM1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H15", "ZCCHC11", "ZCCHC8", "ZFPL1", "ZFR", "ZMPSTE24", "ZMYM1", "ZMYM2", "ZMYM4", "ZNF281", "ZNF598", "ZNF622", "ZNF644", "ZNHIT2", "ZW10", "ZYX"], "leading_proteins": ["ABCB7", "ABCC4", "ABCD4", "ACAT2", "ACOX3", "ACP2", "ACP6", "ADA", "ADK", "AHCYL1", "AIFM1", "AKT2", "ALCAM", "ALDH1A2", "ALDH1B1", "APLP2", "APP", "ARHGAP10", "ASNA1", "ATL2", "ATL3", "ATP2A2", "ATP5A1", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "AURKA", "B4GALT1", "B4GALT3", "BAG6", "BAIAP2", "BCR", "BECN1", "CAMK1", "CAMK2G", "CAPN2", "CAPN5", "CBX1", "CBX3", "CBX5", "CDC20", "CDC37", "CDC42BPB", "CDK1", "CHKA", "CHUK", "CLSTN3", "CLUH", "CMSS1", "COPB2", "COPG1", "COPS3", "CPT2", "CPVL", "CRTAP", "CTSA", "CYB5D2", "CYFIP1", "CYFIP2", "CYP51A1", "DCAF8", "DHCR24", "DHX15", "DHX29", "DHX37", "DHX38", "DHX57", "DHX8", "DHX9", "DNM3", "DOCK7", "DSC3", "DSG2", "ECE1", "EDC4", "EEA1", "EEF1D", "EHD4", "ELMO2", "ELP1", "EPS15", "ERAP1", "ERC1", "FECH", "FOXRED1", "GALNT1", "GID8", "GLB1", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GOLGA2", "GPATCH4", "GSR", "HDAC1", "HDAC2", "HDGFL2", "HEATR6", "HINT2", "HOOK1", "HOOK2", "HOOK3", "IGBP1", "IGF2BP2", "IGF2R", "IMPAD1", "IPO5", "IPO8", "IQGAP1", "IQGAP3", "ITSN2", "KCTD21", "KDELR1", "KDM1B", "KIF11", "KIF22", "KIF23", "KIF3A", "KIF4A", "KIF5B", "LAMB1", "LAPTM4A", "LGMN", "LNPEP", "M6PR", "MAP2K1", "MAPRE2", "MBOAT7", "MCL1", "MCM6", "MFAP1", "MICU2", "MPC2", "MPRIP", "MPV17", "MPV17L2", "MTCH2", "NAA16", "NAMPT", "NAP1L4", "ND1", "NDUFS6", "NPEPPS", "NSD1", "NSD2", "NSMCE3", "NT5DC2", "NUCB1", "NUCB2", "NUP54", "NUP93", "OCLN", "OPA1", "OXA1L", "OXSR1", "PAK2", "PAK4", "PARL", "PDCD4", "PDZD11", "PGRMC2", "PKN2", "PLA2G15", "PLBD2", "PLD6", "POMGNT2", "PPT1", "PPT2", "PRC1", "PRCP", "PRKAG1", "PTGR2", "PTPRF", "PXMP2", "RALA", "RANBP2", "RANBP6", "RAPGEF2", "RCN2", "RHEB", "RHOG", "ROCK2", "RPN1", "SCARB1", "SCARB2", "SCPEP1", "SDF4", "SEC13", "SEC23B", "SEH1L", "SEPT11", "SET", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A32", "SLC25A33", "SLC25A42", "SLC25A44", "SLC2A1", "SLC33A1", "SLC35B2", "SLC35F2", "SLC39A11", "SLC4A7", "SLC7A1", "SLC7A5", "SMN1*", "SNX2", "SORT1", "SPPL2A", "STK26", "STK4", "STOM", "STX10", "STX6", "STX7", "SUN2", "SURF4", "SV2A", "SYNJ2BP", "SYS1", "TBC1D10B", "TBC1D15", "TFRC", "TGOLN2", "THOP1", "TM9SF2", "TM9SF3", "TMEM165", "TOMM40", "TPBG", "TPM1", "TPM4", "TPP1", "TSFM", "TUBGCP3", "TWNK", "TXLNA", "TXLNG", "UBE4A", "UBE4B", "UGCG", "UNC119B", "UPF1", "UQCRC2", "USP22", "USP28", "USP38", "USP47", "USP7", "VAMP7", "XPO4", "XRCC6", "ZMPSTE24", "ZMYM1", "ZMYM2"]} \ No newline at end of file diff --git a/pharos_protein_category/advanced/idx2term.json b/pharos_protein_category/advanced/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..9e26dfeeb6e641a33dae4961196235bdb965b21b --- /dev/null +++ b/pharos_protein_category/advanced/idx2term.json @@ -0,0 +1 @@ +{} \ No newline at end of file diff --git a/pharos_protein_category/basic/idx2term.json b/pharos_protein_category/basic/idx2term.json new file mode 100644 index 0000000000000000000000000000000000000000..c4c8ea0916980a7727ada1e41a5e12e075ffc500 --- /dev/null +++ b/pharos_protein_category/basic/idx2term.json @@ -0,0 +1 @@ +{"0": "Tclin", "1": "Tbio"} \ No newline at end of file diff --git a/pharos_protein_category/basic/plot_0.png b/pharos_protein_category/basic/plot_0.png new file mode 100644 index 0000000000000000000000000000000000000000..7660084cfcf06300c8e1e9747c24496eca5b850e --- /dev/null +++ b/pharos_protein_category/basic/plot_0.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:9fc808cfcd6dc801efaf16811f20a17ef1174a526eecf9c648c14636a335444e +size 121505 diff --git a/pharos_protein_category/basic/plot_1.png b/pharos_protein_category/basic/plot_1.png new file mode 100644 index 0000000000000000000000000000000000000000..ca38d945c7e14aa2465fe775356984897e91fd75 --- /dev/null +++ b/pharos_protein_category/basic/plot_1.png @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:4107e7159a4b3672f96d6430c54fbbc2b5d8c006166776af087f28090d7d3fd4 +size 133111 diff --git a/pharos_protein_category/consensus.joblib b/pharos_protein_category/consensus.joblib new file mode 100644 index 0000000000000000000000000000000000000000..ee37f58fc64875513f44e3fdb4175d0500c319f9 --- /dev/null +++ b/pharos_protein_category/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:93ede5484fbdb01e9a37b1773ce16dadfab9d7454924f85a0a2282b304acb4a8 +size 80226 diff --git a/pharos_protein_category/df_merge.tsv b/pharos_protein_category/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..c57981107d970e936c6c67aa07afef8fff633223 --- /dev/null +++ b/pharos_protein_category/df_merge.tsv @@ -0,0 +1 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 diff --git a/pharos_protein_category/metrics.json b/pharos_protein_category/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..75977b94363e3a46d81b18452d0c8cdf26369dac --- /dev/null +++ b/pharos_protein_category/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 4, + "title": "Average number of proteins per term", + "value": 910.25 +} \ No newline at end of file diff --git a/pharos_protein_category/paths.json b/pharos_protein_category/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..66aef1cab1077cfe7a9e2034a64886874ea52687 --- /dev/null +++ b/pharos_protein_category/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/pharos_protein_category/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/pharos_protein_category/result.tsv b/pharos_protein_category/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..2a4c4b641e72410b0e5ecf82e85c65cd846634e3 --- /dev/null +++ b/pharos_protein_category/result.tsv @@ -0,0 +1,3 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Tclin 0.4046141715634615 1.8101070567738533 0.0702791868633689 0.2528458492230174 0.2811167474534759 100 P03886,Q99720,P28074,O43676,Q16739,P20618,Q13464,O75251,O75116,Q7L0J3,P10253,P06280,P00813,P00390,P48735,O75380,P49721 17 +Tbio 0.1864260526482342 0.2298175884770863 0.8182335168705435 0.9989084208850642 1.0 2776 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493 diff --git a/pharos_protein_category/selections.json b/pharos_protein_category/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..b5b47ef3ffc74aad606a6b5ea8816cd643497f58 --- /dev/null +++ b/pharos_protein_category/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Tbio", "Tchem", "Tclin", "Tdark"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "ALYREF", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOC1", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BAIAP2", "BAK1", "BANF1", "BAP18", "BASP1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCR", "BCS1L", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIP1", "BRIX1", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf76", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf198", "C1orf35", "C2CD2", "C2CD2L", "C2CD5", "C2orf49", "C3orf33", "C3orf58", "C5orf24", "C5orf51", "C8orf33", "C9orf64", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALM3", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCDC94", "CCDC97", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2A", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPH", "CENPK", "CENPP", "CENPU", "CENPV", "CEP131", "CEP170", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD2", "COMMD6", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX14", "COX15", "COX18", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX27", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERICH1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM160B2", "FAM162A", "FAM173A", "FAM177A1", "FAM207A", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FAU", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FN3KRP", "FNBP1", "FNBP4", "FNDC3A", "FNTA", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC1", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH11", "GPATCH4", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KNOP1", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L1RE1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC45", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYRM2", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRFAP1", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL45", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS6", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTF2", "MTFP1", "MTFR1", "MTG1", "MTHFD1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYEF2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFB", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKBIL1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAWR", "PAX6", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD11", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PET100", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2A", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PXMP4", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "R3HCC1", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB34", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN2", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCOC", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLAIN2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35A4", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG1", "SMG8", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TCP11L1", "TCTN3", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THADA", "THAP11", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM131", "TMEM14C", "TMEM160", "TMEM161A", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM30A", "TMEM33", "TMEM35B", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMPO", "TMPO", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1AIP2", "TOR1AIP2", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPO", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBL5", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", 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Q92538,Q99720,P46379,O96008,Q6NT16,Q8IXU6,O43772,Q15629,Q9H1P3,Q7L0J3,Q13505,Q99442,O75027,Q9HC21,Q13432,A2RRP1,P21796,P20645,Q9Y487,P53985,Q9BQT8,A6NIH7,Q8IUD2,Q8TB61,Q96L92,Q8NHS3,P30825,P24390,O00410,P00403,P03886,O00461,P00846,Q96JB2,P45880,Q93050,Q9Y678,P61020,P41440,O60749,Q96CU9,P31749,P49792,Q9H4L5,Q9H814,Q9Y5X1,Q15437,Q99523,Q9UJC3,O43681,O75380,Q9NUN5,Q14728,Q8WUH2,Q96FV9,Q96EE3,Q8N2H4,Q01650,Q99595,Q9H813,Q9HCU5,Q9Y619,Q9Y666,Q9Y6C9,Q8N1S5,P11717,O95563,Q8N4V1,O00400,O60518,O95168,O43676,P12270,P16615,P42566,Q9C0E2,O14678,Q96ED9,Q9HD20,Q15758,Q13769,Q6DKK2,Q96D46,Q9Y282,O60499,O15127,O15078,P23786,P55735,O75431,O75964,Q567U6,Q9H4I9,P25705,O95219,O60826,Q9BSK2,Q86VD7,O15118,Q9HD42,Q96H78,Q96C92,Q8TD16,O43169,P11166,Q70HW3,Q9UBX3,Q9NWR8,O75251,Q6P4Q7,Q9Y6M1,Q9BPX6,P22695,O43707,Q8N1F7,Q969M3,Q9Y6M7,Q15012,P61916,P31751,Q6ZVM7,Q9UPN4,A0AVF1,Q9P2E9,P14373,Q9Y5X2,Q08379,P49321,Q14203,P55011,Q9BTX1,Q8IWJ2,P51790,O43752,O14523,P51798,Q96PU8,P51809,P35606,O75306,Q969Q5,Q96RK4,Q9H2U1 143 +Cell division 0.3073358600510349 0.8840775336849718 0.3766543600292371 1.0 0.6138071052328309 166 Q86XL3,Q8NBT2,P06493,Q6NUK4,Q96EE3,Q9HD42,Q6P1K2,Q96C92,Q8N3U4,Q16763,Q02241,Q9H6D7,Q8WVM7,O95347,P11233,Q9NTJ3,Q12834,Q9H7Z3,P50748,Q9Y6D9,Q9NTI5,O60566,Q8IY18,Q08379,P12270,Q14203,O75935,Q9NXR1,Q15021,Q9H981,Q14457,Q6DKK2,P23396,P48729,Q8NFH4,Q9UJX3,P52732,Q9NRZ9,Q96EA4,Q9Y448,Q16513,Q29RF7,Q15691,P11802,Q15555,O75400,Q9UQE7,O94927,Q9Y5X1,Q96CS2,Q96IY1,Q9Y6A5,Q9HC35,O43663,Q9NVA2,Q2NKX8 56 +Lipid biosynthesis 0.3355819857452257 0.8705869379685001 0.3839797310440902 1.0 0.6182736144838309 64 O00116,Q96N66,P54619,Q16850,Q9HCL2,P27544,Q8WUK0,Q16739,Q15392,Q14739,P35790,Q9Y6K0,Q9UBM7,Q9H3P7,Q96G23 15 +Hearing 0.5674265311727474 0.8383349455609375 0.4018426146775931 1.0 0.6371558575068142 2 Q9UM54 1 +Neurogenesis 0.325905906155609 0.7243079998145479 0.4688766667737383 1.0 0.7161868413627898 56 Q14012,Q9P2X3,Q7L576,O94813,Q13555,Q16352,Q96N67,P35222,P48681,Q8WUJ1,Q15375,Q9Y4G8,Q9NXR1,Q12834,Q8WUB8,Q96EK5,P31749 17 +RNA-mediated gene silencing 0.3852453711779485 0.7134887871082832 0.4755433491985168 1.0 0.7161868413627898 20 Q5TAX3,O75569,Q9HCE1,Q6ZN17,Q9Y2W6,Q9UKZ1,O75175 7 +Myogenesis 0.5223325440767245 0.7089472508225594 0.4783572115197967 1.0 0.7161868413627898 6 Q9Y5B6,Q14331 2 +Sphingolipid metabolism 0.4383716400378152 0.6867051216065514 0.4922685688678836 1.0 0.7219939010062294 11 P04062,Q16739,P07602,O95470 4 +Complement pathway 0.5229332600933723 0.6540296704073337 0.5130926902752795 1.0 0.7397385053133698 2 Q07021 1 +Transcription termination 0.5810439560439574 0.6504154350023293 0.5154239098015845 1.0 0.7397385053133698 3 Q08211,Q9UNY4 2 +DNA condensation 0.4773603724598747 0.6446240604869592 0.5191708388425114 1.0 0.7397385053133698 7 O95347,Q15003,Q15021,Q9NTJ3 4 +GPI-anchor biosynthesis 0.5053094692166757 0.6415284520358977 0.5211794014707833 1.0 0.7397385053133698 6 Q969N2 1 +Sterol biosynthesis 0.3754322871061334 0.5859347168704839 0.557919386277332 1.0 0.7685437439318707 17 Q9UBM7,Q16850,Q15392 3 +Sensory transduction 0.4342442420228783 0.5810948520308948 0.5611765280256056 1.0 0.7685437439318707 9 Q13432,O60313,P50897,Q6P4Q7,Q96RK4 5 +Vision 0.4342442420228783 0.5810948520308948 0.5611765280256056 1.0 0.7685437439318707 9 Q13432,O60313,P50897,Q6P4Q7,Q96RK4 5 +Cholesterol biosynthesis 0.3775579034811605 0.5449722474972317 0.5857726050365053 1.0 0.7930459883571148 16 Q9UBM7,Q16850,Q15392 3 +Antiport 0.4210684096599653 0.5234680019055123 0.6006486127192601 1.0 0.8069782888441968 9 P41440,P51790 2 +Apoptosis 0.2804746596493479 0.4939767930337188 0.6213225691163706 1.0 0.816065463914039 136 P46379,Q07820,Q96KA5,O00291,P05067,O60313,P21796,Q9UHX1,Q9BY67,Q96JJ3,O95831,Q15375,Q9H2J4,Q14457,P23396,Q13464,Q96F07,P52756,Q9BXK5,Q14185,Q9NWH9,Q96A26,P31751 23 +DNA recombination 0.3431657890578004 0.4785520714002336 0.6322573219667729 1.0 0.8182390008539264 26 Q9H981,P12956 2 +Lipid transport 0.3318431006500589 0.4654995458957347 0.6415737620331923 1.0 0.8182390008539264 30 Q99720 1 +Respiratory chain 0.3104899381012032 0.4520577056556225 0.6512274116076315 1.0 0.8219461775341149 42 P03886,O43676,O75251,O75380,Q96CU9,Q6DKK2 6 +Antiviral defense 0.3313609683264614 0.4444906385911095 0.6566878955757425 1.0 0.8219461775341149 29 Q13325,Q7Z434,Q9NUQ8,P42224,Q9BUI4,P55265,Q9NRW3,Q9H2U1,Q14457 9 +Biological rhythms 0.2952640366561834 0.3606616912425673 0.7183523657853379 1.0 0.8596353664157964 45 Q15233,Q9Y2K7,P43490,O75116,Q93009,O75592,P23246 7 +Exocytosis 0.3338329664443671 0.35304097057643 0.7240577255370351 1.0 0.8596353664157964 17 Q9BRK5,Q9UPT5,P51809,Q8TAG9,O00443,Q96KP1 6 +Tetrahydrobiopterin biosynthesis 0.4383411150782698 0.3486446653965739 0.7273560910807881 1.0 0.8596353664157964 2 P09417 1 +Sterol metabolism 0.3116495609945558 0.3043579498136973 0.7608552002322171 1.0 0.8778055237141689 28 Q16850,O15118,P61916,Q15392,Q9UBM7 5 +Cholesterol metabolism 0.3129320229589945 0.3014225488911466 0.7630923018651581 1.0 0.8778055237141689 27 Q16850,O15118,P61916,Q15392,Q9UBM7 5 +Wnt signaling pathway 0.2998758973296697 0.2870469575853267 0.7740763654494649 1.0 0.884658703370817 32 P48729,Q9UPN3,Q96AC1,Q5T9L3,P35222,Q9NWU2,Q9P1Z2,Q92541,Q6DKJ4,Q6PD62,Q8N7H5,P67870 12 +Steroid biosynthesis 0.3041713824151679 0.2334963569457774 0.8153759981211044 1.0 0.925846294640738 23 Q9UBM7,Q16850,Q15392,Q14739 4 +Leukotriene biosynthesis 0.3781928041746739 0.1891125924141767 0.8500045722478096 1.0 0.9528713676153788 2 Q99735 1 +Steroid metabolism 0.286978504578313 0.181742664469294 0.8557846821033779 1.0 0.9532791395581932 30 Q16850,O15118,P61916,Q15392,Q9UBM7 5 +Electron transport 0.2609995169122672 0.1298968493915733 0.8966480369915999 1.0 0.98631284069076 57 P03886,O43676,O75251,O43169,O75380,Q96CU9,Q6DKK2 7 +Sodium transport 0.311402180359982 0.081442077797458 0.9350903869880144 1.0 1.0 6 Q9Y6M7 1 +Glucose metabolism 0.2711191671050887 0.0448821431884039 0.964201250171576 1.0 1.0 11 P11177,P31751,Q15118,P31749 4 +Necrosis 0.2718526663001709 0.0306242961265437 0.9755691657277124 1.0 1.0 5 Q96HS1,O00429,P30405,P04637 4 diff --git a/protein_atlas_biological_process/selections.json b/protein_atlas_biological_process/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..29d4c33464cb1d612ba0d7681065f870b5ef9017 --- /dev/null +++ b/protein_atlas_biological_process/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["ATP synthesis", "Adaptive immunity", "Amino-acid biosynthesis", "Amino-acid transport", "Angiogenesis", "Anion exchange", "Antiport", "Antiviral defense", "Apoptosis", "Arginine metabolism", "Aromatic hydrocarbons catabolism", "Asparagine biosynthesis", "Autophagy", "B-cell activation", "Behavior", "Bile acid catabolism", "Biological rhythms", "Biomineralization", "Blood coagulation", "Branched-chain amino acid biosynthesis", "Branched-chain amino acid catabolism", "Calcium transport", "Carbohydrate metabolism", "Catecholamine metabolism", "Cell adhesion", "Cell cycle", "Cell division", "Cell shape", "Chemotaxis", "Cholesterol biosynthesis", "Cholesterol metabolism", "Chromosome partition", "Cilium biogenesis/degradation", "Coenzyme A biosynthesis", "Collagen degradation", "Complement pathway", "Cysteine biosynthesis", "DNA condensation", "DNA damage", "DNA excision", "DNA recombination", "DNA repair", "DNA replication", "DNA synthesis", "Detoxification", "Differentiation", "ER-Golgi transport", "Electron transport", "Endocytosis", "Erythrocyte maturation", "Exocytosis", "Fatty acid biosynthesis", "Fatty acid metabolism", "Fertilization", "Fucose metabolism", "GMP biosynthesis", "GPI-anchor biosynthesis", "Galactose metabolism", "Gastrulation", "Gluconate utilization", "Gluconeogenesis", "Glucose metabolism", "Glutathione biosynthesis", "Glycogen biosynthesis", "Glycogen metabolism", "Glycolysis", "Glyoxylate bypass", "Growth arrest", "Growth regulation", "Hearing", "Heme biosynthesis", "Hemostasis", "Host-virus interaction", "Hydrogen ion transport", "Hypusine biosynthesis", "Immunity", "Inflammatory response", "Inhibition of host STAT1 by virus", "Inhibition of host STAT2 by virus", "Inhibition of host innate immune response by virus", "Inhibition of host interferon signaling pathway by virus", "Innate immunity", "Inositol biosynthesis", "Ion transport", "Isoprene biosynthesis", "Keratinization", "Leukotriene biosynthesis", "Lipid biosynthesis", "Lipid degradation", "Lipid metabolism", "Lipid transport", "Meiosis", "Melanin biosynthesis", "Menaquinone biosynthesis", "Methionine biosynthesis", "Methotrexate resistance", "Mitosis", "Molybdenum cofactor biosynthesis", "Myogenesis", "Necrosis", "Neurogenesis", "Neurotransmitter degradation", "Neurotransmitter transport", "Nonsense-mediated mRNA decay", "Notch signaling pathway", "Nucleotide biosynthesis", "Nucleotide metabolism", "One-carbon metabolism", "Oogenesis", "Osteogenesis", "Pentose shunt", "Peptide transport", "Peroxisome biogenesis", "Phagocytosis", "Phenylalanine catabolism", "Phospholipid biosynthesis", "Phospholipid metabolism", "Plasminogen activation", "Polyamine biosynthesis", "Porphyrin biosynthesis", "Potassium transport", "Proline biosynthesis", "Proline metabolism", "Prostaglandin biosynthesis", "Prostaglandin metabolism", "Protein biosynthesis", "Protein transport", "Purine biosynthesis", "Purine salvage", "Pyridine nucleotide biosynthesis", "Pyridoxine biosynthesis", "Pyrimidine biosynthesis", "RNA-mediated gene silencing", "Respiratory chain", "Ribosome biogenesis", "Sensory transduction", "Serine biosynthesis", "Sodium transport", "Sodium/potassium transport", "Spermatogenesis", "Spermidine biosynthesis", "Sphingolipid metabolism", "Steroid biosynthesis", "Steroid metabolism", "Sterol biosynthesis", "Sterol metabolism", "Stress response", "Sugar transport", "Symport", "Tetrahydrobiopterin biosynthesis", "Transcription", "Transcription regulation", "Transcription termination", "Translation regulation", "Translocation", "Transport", "Tricarboxylic acid cycle", "Tyrosine catabolism", "Ubiquinone biosynthesis", "Ubl conjugation pathway", "Unfolded protein response", "Urea cycle", "Viral RNA replication", "Viral immunoevasion", "Viral penetration into host nucleus", "Virus entry into host cell", "Vision", "Wnt signaling pathway", "Xylose metabolism", "Zinc transport", "mRNA capping", "mRNA processing", "mRNA splicing", "mRNA transport", "rRNA processing", "tRNA processing"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF3", "ABHD12", "ABHD6", "ABI1", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT7", "ACOT8", "ACOX1", "ACOX3", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN4", "ACTR3", "ACTR8", "ADA", "ADAM17", "ADAR", "ADI1", "ADK", "ADNP", "ADPGK", "ADSL", "ADSS", "AFDN", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AKAP17A", "AKAP8", "AKAP8L", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH3A2", "ALDH4A1", "ALDOA", "ALDOC", "ALKBH5", "AMFR", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANXA1", "ANXA11", "ANXA2", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEX1", "API5", "APOBEC3C", "APOC1", "APOL2", "APOO", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP2", "ARG2", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL8B", "ARMC10", "ARMT1", "ARRB2", "ARV1", "ARVCF", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ATAD2", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATRX", "AUP1", "AURKA", "AURKB", "BABAM2", "BAG3", "BAG6", "BAK1", "BANF1", "BAZ1A", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCL2L12", "BCL2L13", "BCLAF1", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BMS1", "BNIP1", "BOP1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BRIX1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C12orf43", "C1QBP", "C2CD2L", "C2CD5", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANX", "CAPRIN1", "CARM1", "CARS", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC124", "CCDC22", "CCDC51", "CCDC86", "CCDC93", "CCDC94", "CD2AP", "CD2BP2", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC42", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPE", "CENPU", "CENPV", "CEP131", "CEP250", "CEP290", "CEPT1", "CERS1", "CERS2", "CETN2", "CFL1", "CHAF1A", "CHAF1B", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHST14", "CHTF18", "CHTOP", "CIAPIN1", "CIRBP", "CISD2", "CKAP2", "CKAP5", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLIC1", "CLIC4", "CLINT1", "CLPTM1", "CLPTM1L", "CLSTN3", "CLTA", "CLTC", "CLU", "CMPK1", "CMTR1", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COMMD2", "COMMD6", "COMMD8", "COMT", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS6", "COPS7A", "COPS7B", "COPZ1", "COQ3", "COQ8A", "CORO7", "COX1", "COX2", "CPNE1", "CPOX", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CRNKL1", "CROT", "CS", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTH", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC15", "CWC22", "CXADR", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN3", "DCUN1D1", "DCXR", "DDA1", "DDB1", "DDRGK1", "DDT", "DDX1", "DDX17", "DDX20", "DDX21", "DDX23", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX46", "DDX47", "DDX5", "DDX51", "DDX54", "DDX56", "DENND4C", "DENR", "DERL1", "DFFA", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DICER1", "DIDO1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLGAP5", "DLST", "DMAP1", "DNAAF5", "DNAJA3", "DNAJB1", "DNAJB12", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DPF2", "DPY30", "DPYSL2", "DSC3", "DSG2", "DST", "DTYMK", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHS1", "ECI1", "ECSIT", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC4", "EMG1", "EML4", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERLIN1", "ERLIN2", "ERO1A", "ERO1B", "ERP44", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAM162A", "FAM208A", "FAM50A", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FIS1", "FKBP15", "FKBP8", "FLII", "FLNA", "FLNB", "FLOT2", "FMR1", "FNBP1", "FOXRED1", "FRG1", "FRYL", "FTSJ3", "FUBP1", "FUBP3", "FUNDC1", "FXR1", "G3BP1", "G3BP2", "G6PD", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GALK1", "GALM", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCC2", "GCFC2", "GCLC", "GCLM", "GCN1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGPS1", "GHITM", "GID8", "GINS2", "GINS3", "GINS4", "GLRX", "GLTP", "GM2A", "GMPS", "GNAI1", "GNAI2", "GNAI3", "GNL2", "GNL3L", "GNPDA1", "GOLGA2", "GOLIM4", "GOLPH3", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPHN", "GPI", "GPKOW", "GPR89B", "GRB2", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSS", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP10", "GTPBP3", "GTPBP4", "GUF1", "GYG1", "GYS1", "H2AFX", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HBS1L", "HCFC1", "HDAC1", "HDAC2", "HDGF", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXIM1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HIP1", "HIP1R", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLTF", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCR", "HMGCS1", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH3", "HNRNPK", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK1", "HOOK2", "HOOK3", "HPF1", "HPRT1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSP90AA1", "HSP90AB1", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBKB", "ILF2", "ILF3", "ILVBL", "IMP3", "IMP4", "IMPACT", "IMPDH1", "IMPDH2", "INA", "INCENP", "INTS3", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITSN2", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JUP", "KARS", "KAT7", "KATNA1", "KCTD21", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0391", "KIAA1468", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIFBP", "KIFC1", "KIN", "KLC1", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRR1", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDLR", "LETM1", "LGALS3", "LGALS3BP", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LMAN1", "LMAN2", "LMBRD1", "LPCAT1", "LPGAT1", "LRPPRC", "LRRC41", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGT1", "MANF", "MAP1S", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARCH5", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MESD", "METTL1", "MFAP1", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGEA5", "MGST2", "MIA3", "MICU1", "MID1", "MIF", "MINDY3", "MKI67", "MLEC", "MMGT1", "MMS19", "MOB4", "MOCOS", "MOCS1", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPP5", "MRE11", "MRI1", "MRM3", "MRPL41", "MRPL58", "MRPS27", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSMO1", "MSN", "MTA1", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTERF3", "MTFP1", "MTG1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTR", "MTX1", "MTX2", "MVD", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYH10", "MYH14", "MYH9", "MYO1C", "MYO1D", "MYO6", "NAA15", "NAE1", "NAF1", "NAMPT", "NAP1L1", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCEH1", "NCK1", "NCKAP1", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF4", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEK3", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIP7", "NIPBL", "NISCH", "NKRF", "NLE1", "NMD3", "NME1", "NME2", "NOA1", "NOC2L", "NOL11", "NOL8", "NOL9", "NONO", "NOP10", "NOP14", "NOP2", "NOP53", "NOP56", "NOP58", "NOSIP", "NOTCH2", "NPC1", "NPC2", "NPLOC4", "NPM1", "NPTN", "NRDE2", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NTHL1", "NUBP2", "NUCKS1", "NUDC", "NUDT16", "NUDT21", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "PA2G4", "PABPC1", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PANK4", "PANX1", "PAPOLA", "PARG", "PARK7", "PARN", "PARP1", "PARP2", "PARVA", "PAWR", "PAX6", "PAXBP1", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH7", "PCID2", "PCK2", "PCM1", "PCNA", "PCNP", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDLIM7", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDZD8", "PECR", "PELO", "PELP1", "PEPD", "PES1", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFKL", "PFKM", "PFKP", "PGAM1", "PGAM5", "PGD", "PGK1", "PGM1", "PGM2", "PGM3", "PGP", "PHAX", "PHB", "PHB2", "PHF10", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIN1", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLIN3", "PLK1", "PLRG1", "PMF1", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "PPAT", "PPHLN1", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPM1F", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R8", "PPP2R1A", "PPP4R2", "PPP5C", "PPP6C", "PPT1", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRDX6", "PREB", "PRIM1", "PRIM2", "PRKAA2", "PRKAG1", "PRKCD", "PRKDC", "PRKRA", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA3", "PSMA4", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC3", "PSMD10", "PSMD14", "PSME3", "PSME4", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTK7", "PTPMT1", "PTPN23", "PTPRF", "PTRH2", "PUDP", "PUF60", "PURA", "PUS1", "PUS7", "PWP1", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QTRT1", "QTRT2", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB35", "RAB39A", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP2", "RANBP3", "RANBP6", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM14", "RBM15", "RBM17", "RBM22", "RBM25", "RBM28", "RBM3", "RBM39", "RBM4", "RBM45", "RBM5", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCOR1", "REEP3", "REEP4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFT1", "RFX1", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN3", "RMI1", "RMND1", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNMT", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPF1", "RPF2", "RPL10", "RPL13A", "RPP14", "RPP30", "RPP40", "RPRD1B", "RPS3", "RPS3A", "RPS6KA1", "RPS6KA3", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP1B", "RRP36", "RRP8", "RRP9", "RRS1", "RSF1", "RSL24D1", "RTCB", "RTF1", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCD", "SCFD1", "SCML2", "SCP2", "SCRIB", "SCRN1", "SCYL1", "SDAD1", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3GL1", "SH3GLB1", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L2", "SKP1", "SKP2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMARCA1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG1", "SMG8", "SMN1*", "SMNDC1", "SMS", "SMU1", "SNAP29", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SON", "SORBS3", "SORT1", "SPAST", "SPATA5", "SPC24", "SPDL1", "SPEN", "SPNS1", "SPTLC1", "SPTLC2", "SRCAP", "SRFBP1", "SRM", "SRPK1", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSBP1", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STAT1", "STAT3", "STAU1", "STK26", "STK4", "STMN1", "STRAP", "STRBP", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX8", "STXBP2", "STXBP3", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNGR2", "SYS1", "TACC3", "TADA3", "TAF10", "TALDO1", "TAMM41", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TBCB", "TBL1XR1", "TBPL1", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCTN3", "TDRKH", "TECR", "TEFM", "TERF2IP", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THRAP3", "TIAL1", 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0000000000000000000000000000000000000000..6d892656824d1e3193d03e5cbe631bd3d5f5bc65 --- /dev/null +++ b/protein_atlas_disease_involvement/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Alzheimer disease 1 6 2.3123300321732096 0.0207595028914764 1.2354368932038835 4.759708737864078 0.431847000352495 0.4019540870993141 1.112770771411099 1.1095472323418396 1.1278893369824603 0.2998522373047794 1.0 0.0727733471903131 0.0098557770733155 0.0557098434243155 0.1812716861639223 +Neuronal ceroid lipofuscinosis 4 5 2.075909286762208 0.0379023416447719 2.1941747572815533 3.616504854368932 0.8145003765175237 0.1716854616439567 0.950812145720796 0.8293870806734848 1.6764073513361384 0.2241811956153294 1.0 0.0550816697898294 0.0001725606130307 0.0025975272437437 0.0001590313802548 +FDA approved drug targets 28 136 2.0577182254610342 0.039617189807475 24.04854368932039 119.4247572815534 0.6623112070438231 0.5745671660823485 8.39802177443113 10.190737689187452 0.8635117376862006 0.3683507047501689 0.2817240684487549 0.0027670616369496 0.0005769894192108 0.006471971429424 0.000352967388882 +Amyotrophic lateral sclerosis 0 13 2.021708149281105 0.0432065114864177 3.0533980582524274 13.87864077669903 0.4936496443371127 0.508408134121438 2.1804655926597256 1.4762949218233254 0.8513354672584855 0.3027847309213633 0.0340030734974357 0.1403531442218371 0.2638774705145789 0.5428479192551358 0.465786591734874 diff --git a/protein_atlas_disease_involvement/metrics.json b/protein_atlas_disease_involvement/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..cd390c92f97a2d0f55264dbc39ce127c0e8f021a --- /dev/null +++ b/protein_atlas_disease_involvement/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 119, + "title": "Average number of proteins per term", + "value": 23.613445378151262 +} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/paths.json b/protein_atlas_disease_involvement/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..a5e3cf714702a03211f4dc58656a5f55f772bf7a --- /dev/null +++ b/protein_atlas_disease_involvement/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_disease_involvement/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_disease_involvement/result.tsv b/protein_atlas_disease_involvement/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..ae7375e8ba45c5635c8dbaeef9c8b0360a3714ba --- /dev/null +++ b/protein_atlas_disease_involvement/result.tsv @@ -0,0 +1,44 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Senior-Loken syndrome 0.9384784399890138 2.4558295401628176 0.0140559812746594 0.8144681203414117 0.128666290129575 2 O15078 1 +Alzheimer disease 0.908991770710667 2.3123300321732096 0.0207595028914764 0.9176175852299588 0.1409828669104992 6 P05067 1 +Niemann-Pick disease 0.9016753639110128 2.302177939284575 0.0213251395326805 0.9230916525629044 0.1409828669104992 2 O15118 1 +Hirschsprung disease 0.8873935731941747 2.241911856066315 0.0249670696294685 0.9506491369082376 0.1556145775468346 2 P42892 1 +Amyloidosis 0.9672074051908356 2.2239217339157773 0.026153710512073 0.9573067467117724 0.1556145775468346 4 P05067 1 +Neuronal ceroid lipofuscinosis 0.8897746014293483 2.075909286762208 0.0379023416447719 0.9899288339381436 0.181273071324155 5 O75503,Q9NWW5,Q8NHS3,P50897 4 +FDA approved drug targets 0.3844726974973508 2.0577182254610342 0.039617189807475 0.991855189418864 0.181273071324155 136 Q99720,P54619,P20618,Q7L0J3,P10253,P00390,P05067,P20645,P02786,P28074,P16615,P80404,O75116,P00813,P49721,P03886,Q16850,P12814,P55011,P23786,Q8N0U8,Q16739,Q13464,Q7LG56,P48735,P11274,P49354,Q13423 28 +Neurodegeneration 0.3652588505985157 1.937653575891102 0.0526655013561274 0.9984008138556162 0.2021675697219086 148 Q99720,Q14108,Q9HD42,Q8TD16,Q71SY5,P02545,O75298,P39210,P54802,O14773,O75503,O00291,P05067,Q8N0X7,O75787,O95831,Q8NHS3,Q96RR1,P03886,Q8IV08,P50897,Q03252,Q9NWW5,P07196 24 +Nephronophthisis 0.8969780219780223 1.86802783701074 0.0617581909211084 0.9994924731537496 0.2157718317482461 3 Q15051,O15078 2 +Congenital muscular dystrophy 0.7119637151195906 1.78189888839931 0.0747657218568007 0.999903627308965 0.2224280225239822 8 P02545,Q9H9S5,O43505 3 +Mucopolysaccharidosis 0.7648433178491962 1.7280139113671538 0.0839857303201117 0.9999707337916156 0.2437634611730071 6 P16278,P08236,P15586,P54802 4 +Neuropathy 0.4222096131757378 1.699504330823472 0.0892241992632045 0.9999852100581328 0.2528018979124129 56 Q15046,Q96RR1,Q7Z406,P00846,Q7LG56,Q14203,O95831,P02545,Q71SY5,P39210,P54802,Q5TAQ9,Q9HC21,P07196,Q00796 15 +Charcot-Marie-Tooth disease 0.5191626310073838 1.6770876179071117 0.0935253497094015 0.9999915797699926 0.2588259678004367 25 O95831,P02545,Q71SY5,P54802,P07196 5 +Leber hereditary optic neuropathy 0.8071972282371774 1.6083754122717475 0.1077529833567061 0.999998718473958 0.2914228413510916 4 P03886 1 +Lissencephaly 0.5893713771159348 1.5481503921545503 0.1215860919003168 0.9999998003794682 0.3130985615716598 13 P07942,O43505,Q8NAT1,Q9H9S5,Q9BSJ2,Q6ZXV5 6 +Premature ovarian failure 0.7278220269156795 1.5470861190181409 0.1218424806701785 0.9999998071949072 0.3130985615716598 2 Q5JTZ9 1 +Dystroglycanopathy 0.7199183817276432 1.5395881474253037 0.1236607764190589 0.9999998493400544 0.3130985615716598 6 Q9H9S5,O43505 2 +Hereditary hemolytic anemia 0.5427519291319538 1.441332905532012 0.1494906553134738 0.9999999957163728 0.3513487889722559 15 P00813,P00390,Q15437 3 +Rhizomelic chondrodysplasia punctata 0.7862797953452549 1.4374926759690367 0.1505780524166811 0.999999996321304 0.3513487889722559 3 O00116 1 +Emery-Dreifuss muscular dystrophy 0.713869970265042 1.3692132127789762 0.1709326370535653 0.9999999997947948 0.3698360692613504 5 P50402,Q8WXH0,P02545 3 +Diabetes mellitus 0.5638141315155148 1.3313617831869784 0.1830699979624483 0.9999999999645188 0.3792167402031319 11 P03886,P31751,O60343,P13807 4 +Spinocerebellar ataxia 0.5683616962370011 1.3210777885303575 0.1864754282501939 0.999999999978417 0.3792167402031319 10 O14773,Q8IV08 2 +Cone-rod dystrophy 0.7554945054945063 1.3164739313863418 0.1880150224536536 0.9999999999827728 0.3792167402031319 3 Q13432,Q6P4Q7 2 +Limb-girdle muscular dystrophy 0.5416565221257691 1.2163521314037162 0.2238508105898118 0.99999999999992 0.4181509762606449 11 P02545,Q9H9S5,Q13049 3 +Dwarfism 0.3543792415147805 0.9941823962378934 0.3201340767926912 1.0 0.5365627484271868 50 O00116,Q8WVQ1,Q96L58,Q7RTS9,O75718,O75419,Q14739,Q13868,O95831,Q96HY6,Q9NUQ7 11 +Leber congenital amaurosis 0.6463803900920908 0.9715950496129652 0.3312520462638471 1.0 0.5417522240266999 4 O15078 1 +Progressive external ophthalmoplegia 0.6458241137268305 0.9694205606088896 0.3323353979323453 1.0 0.5417522240266999 4 Q96RR1 1 +Gangliosidosis 0.6029118619948475 0.9162217251699524 0.3595506129689894 1.0 0.559996199773426 5 P07602 1 +Primary mitochondrial disease 0.3288626518931417 0.9098683806745076 0.3628919268249619 1.0 0.559996199773426 110 Q9BRT2,P39210,Q7KZN9,O60313,Q70HW3,Q9UBX3,O43676,Q9BQT8,O95831,O75251,Q9BUB7,Q96RR1,Q6DKK2,P00403,P03886,P22695,Q9Y3D3,P00846,Q7LG56,Q9Y2R0,Q96CU9,Q9NWS8,O75306,P25705,O75380,Q8NFF5 26 +Leigh syndrome 0.4617057787607065 0.8036815576971914 0.4215809077139509 1.0 0.619359605160002 11 Q7KZN9,P00846 2 +Bardet-Biedl syndrome 0.5292725514243506 0.7368477431534431 0.4612149456603234 1.0 0.665333784586284 6 Q13049,O15078 2 +Epilepsy 0.3090273815462724 0.6314571743678824 0.5277416424673302 1.0 0.7292850980513733 76 P03886,P11166,Q14108,P22466,P16615,O75787,Q96N67,Q03252,Q9Y4G8,Q96F07,O75503,Q969N2,Q13813 13 +Disease variant 0.2563258310986825 0.5370635289880855 0.591223732089547 1.0 0.7817291568739566 888 P22830,Q99720,Q86XL3,Q01105,P26038,P27544,Q7RTS9,O43772,O75419,Q8N201,O75027,O75503,P00390,Q9HC21,Q9Y6D9,P05067,Q16625,P13807,Q13432,A2RRP1,O60313,P22466,P53985,Q15392,O95831,Q8NHS3,P42892,P00813,P10619,P03886,P07602,Q8IV08,P50897,P00846,O75530,Q96CU9,O00584,P08670,Q15437,Q16740,O75380,P07196,P55263,Q4J6C6,Q71SY5,P54802,P06280,Q00796,P16278,Q9UHX1,P28070,O43676,P16615,O14678,Q13868,P32929,Q13049,O15078,P23786,O43505,Q03252,O15484,P09493,P35580,P04066,Q9NX62,P25705,Q9NWW5,O60826,O75844,Q86VD7,Q14108,O15344,O15118,Q8TD16,P02545,P10253,P39210,Q9Y5Z9,Q9Y366,Q9UBM7,Q7KZN9,P35579,P11166,Q70HW3,Q9UBX3,Q96L58,Q7Z406,O75787,O75718,O75251,Q6P4Q7,Q96RR1,Q969N2,Q92542,Q13813,P50336,P22695,P12814,P52732,O43707,Q96F07,Q9Y448,Q9H9S5,Q8N1F7,P48735,Q96N66,Q13423,P61916,O75569,P31751,Q9NQH7,Q8NFF5,O00116,Q9HC07,Q8WVM7,P06753,O75298,O14773,Q9Y4X5,Q8NCH0,Q8WVQ1,P49748,Q8N0X7,P02786,P80404,P15586,Q14739,Q6ZXV5,O14936,O00754,Q8WXW3,Q7LG56,P11177,P08236,P51798,Q9NPF0,Q9BX67,Q9NWS8,Q9UQE7,P35606,O75306,Q8NAT1,Q9BSJ2,Q96RK4,Q9NUQ7,Q9UEY8 147 +Primary microcephaly 0.3968069674785336 0.5020030817385844 0.615665353207326 1.0 0.7971536103365124 12 Q86XL3,Q8NFH4,P35606,Q15021,Q15003 5 +Obesity 0.3977550553937432 0.4803651540686402 0.6309677674930412 1.0 0.7987783439539564 10 Q13049,O15078 2 +Leukodystrophy 0.3562017532919258 0.4289092539423259 0.6679892654836317 1.0 0.8081687941956847 16 P07602 1 +Deafness 0.2905994643051936 0.3854060005303895 0.6999366375363638 1.0 0.8246778204636366 58 O76024,Q9H1P3,P35579,O00400,O60313,Q7Z406,O95831,Q13868,Q96RR1,Q9NSV4,Q969T9,Q8N2K0,Q8NB90,Q15046,Q15067,Q9NWM8,P62266,Q16740,Q9NR28,Q9BV73 20 +Parkinsonism 0.3670414993088068 0.3565076091211175 0.7214604546975345 1.0 0.8392151406208358 11 O75569,O75787 2 +Non-syndromic deafness 0.3222051492308682 0.3312125415227183 0.7404839476066198 1.0 0.8392151406208358 20 P35579,Q15046,Q7Z406,O76024,Q9H1P3,Q9NR28,Q9NSV4,Q969T9 8 +Cardiomyopathy 0.31793788708612 0.3133971826178996 0.7539789244391872 1.0 0.8464480378138045 25 P31040,O60313,P49748,P50402,P00846,P02545,Q5JTZ9,Q9H9S5,P09493,P19022 10 +Retinitis pigmentosa 0.2968593062128244 0.2044681626731639 0.8379876689315202 1.0 0.8983831766022604 18 P00846 1 +Microphthalmia 0.3220572057205815 0.1297847666668152 0.8967367154092918 1.0 0.9295707045687392 7 O60493,Q9NP58,A6NHR9,Q5SRE5,P41227,P53701 6 +Proto-oncogene 0.2523248806879512 0.0527426483403972 0.957936957833835 1.0 0.966055067645986 45 Q01105,P35637,P12270,P42566,Q9BZ95,Q01844,P14373,P06753,Q5M775,Q92734,Q92804,P31751,O96028,P11274,P31749,Q96L73 16 diff --git a/protein_atlas_disease_involvement/selections.json b/protein_atlas_disease_involvement/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..24140f70dd8e5b78784242719864f1f51f87960c --- /dev/null +++ b/protein_atlas_disease_involvement/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Aicardi-Goutieres syndrome", "Albinism", "Allergen", "Alport syndrome", "Alzheimer disease", "Amelogenesis imperfecta", "Amyloidosis", "Amyotrophic lateral sclerosis", "Atrial fibrillation", "Autism", "Autism spectrum disorder", "Bardet-Biedl syndrome", "Bartter syndrome", "Cancer-related genes", "Cardiomyopathy", "Cataract", "Charcot-Marie-Tooth disease", "Ciliopathy", "Cockayne syndrome", "Cone-rod dystrophy", "Congenital adrenal hyperplasia", "Congenital disorder of glycosylation", "Congenital dyserythropoietic anemia", "Congenital hypothyroidism", "Congenital muscular dystrophy", "Congenital myasthenic syndrome", "Corneal dystrophy", "Craniosynostosis", "Cushing syndrome", "Deafness", "Diabetes insipidus", "Diabetes mellitus", "Diamond-Blackfan anemia", "Disease variant", "Dwarfism", "Dyskeratosis congenita", "Dystonia", "Dystroglycanopathy", "Ectodermal dysplasia", "Ehlers-Danlos syndrome", "Elliptocytosis", "Emery-Dreifuss muscular dystrophy", "Epidermolysis bullosa", "Epilepsy", "FDA approved drug targets", "Fanconi anemia", "Gangliosidosis", "Gaucher disease", "Glaucoma", "Glutaricaciduria", "Glycogen storage disease", "Gout", "Hereditary hemolytic anemia", "Hereditary multiple exostoses", "Hereditary nonpolyposis colorectal cancer", "Hereditary spastic paraplegia", "Hermansky-Pudlak syndrome", "Hirschsprung disease", "Holoprosencephaly", "Hypogonadotropic hypogonadism", "Hypotrichosis", "Ichthyosis", "Intrahepatic cholestasis", "Joubert syndrome", "Kallmann syndrome", "Kartagener syndrome", "Leber congenital amaurosis", "Leber hereditary optic neuropathy", "Leigh syndrome", "Leukodystrophy", "Li-Fraumeni syndrome", "Limb-girdle muscular dystrophy", "Lissencephaly", "Long QT syndrome", "MELAS syndrome", "Maple syrup urine disease", "Meckel syndrome", "Mental retardation", "Metachromatic leukodystrophy", "Microphthalmia", "Mucopolysaccharidosis", "Myofibrillar myopathy", "Nemaline myopathy", "Nephronophthisis", "Neurodegeneration", "Neuronal ceroid lipofuscinosis", "Neuropathy", "Niemann-Pick disease", "Non-syndromic deafness", "Obesity", "Oncogene", "Osteogenesis imperfecta", "Osteopetrosis", "Palmoplantar keratoderma", "Parkinson disease", "Parkinsonism", "Peroxisome biogenesis disorder", "Peters anomaly", "Phenylketonuria", "Pontocerebellar hypoplasia", "Premature ovarian failure", "Primary ciliary dyskinesia", "Primary hypomagnesemia", "Primary microcephaly", "Primary mitochondrial disease", "Progressive external ophthalmoplegia", "Proto-oncogene", "Pyropoikilocytosis", "Retinitis pigmentosa", "Rhizomelic chondrodysplasia punctata", "SCID", "Schizophrenia", "Senior-Loken syndrome", "Spinocerebellar ataxia", "Systemic lupus erythematosus", "Tumor suppressor", "Williams-Beuren syndrome", "Xeroderma pigmentosum", "Zellweger syndrome"], "available_proteins": ["AAAS", "AAGAB", "AARS", "AARS2", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCC1", "ABCD4", "ABHD11", "ABHD12", "ABI1", "ACAA1", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACLY", "ACO1", "ACO2", "ACOX1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ADA", "ADAR", "ADD3", "ADK", "ADNP", "ADSL", "AFDN", "AFG3L2", "AGK", "AGL", "AGPS", "AHCY", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AKAP12", "AKAP13", "AKR1B1", "AKT1", "AKT2", "ALCAM", "ALDH18A1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "AMPD2", "ANAPC1", "ANK3", "ANKLE2", "ANLN", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA7", "AP1B1", "AP1S1", "AP1S2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP4M1", "APEX1", "APOC1", "APOL2", "APP", "APRT", "ARCN1", "ARG2", "ARHGDIA", "ARHGEF2", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARV1", "ASAH1", "ASCC1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD3A", "ATG5", "ATIC", "ATL3", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1E1", "ATPAF2", "ATRX", "ATXN10", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GAT1", "BAG3", "BANF1", "BAZ1B", "BBS4", "BCAP31", "BCAS3", "BCAT2", "BCKDK", "BCLAF1", "BCR", "BCS1L", "BICD2", "BIRC6", "BLM", "BLMH", "BMS1", "BPTF", "BRAT1", "BRCA1", "BRD3", "BRD4", "BRI3BP", "BRIP1", "BUB1B", "BUD23", "C12orf57", "C19orf70", "C1QBP", "C3orf58", "CAD", "CADM1", "CALM3", "CALR", "CAMK2G", "CANT1", "CANX", "CAPN1", "CAPN5", "CARM1", "CARS", "CASK", "CAST", "CC2D1A", "CCAR1", "CCAR2", "CCDC22", "CCDC47", "CCDC51", "CCDC6", "CCT5", "CD320", "CDC20", "CDC27", "CDC37", "CDC42", "CDC45", "CDC73", "CDH2", "CDK1", "CDK2", "CDK4", "CDK5", "CDK5RAP2", "CDK6", "CDKAL1", "CENPE", "CEP250", "CEP290", "CERS1", "CFL2", "CHAMP1", "CHD1", "CHD4", "CHD7", "CHD8", "CHEK2", "CHMP1A", "CHMP2B", "CHMP4B", "CHST14", "CISD2", "CIZ1", "CKB", "CKMT1A*", "CLCC1", "CLCN7", "CLIC1", "CLN5", "CLN6", "CLPB", "CLPP", "CLPX", "CLTC", "CLU", "CNNM4", "CNOT1", "CNOT3", "COA3", "COA7", "COASY", "COG5", "COG6", "COG7", "COG8", "COLGALT1", "COMT", "COPA", "COPB2", "COQ8A", "COX1", "COX14", "COX15", "COX2", "COX4I1", "COX5A", "CPOX", "CPSF1", "CPT1A", "CPT2", "CRK", "CRTAP", "CSDE1", "CSE1L", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSTB", "CTBP1", "CTH", "CTNNB1", "CTNNBL1", "CTNND1", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CWC27", "CWF19L1", "CYB5R3", "CYC1", "CYFIP2", "CYP51A1", "DAD1", "DARS", "DARS2", "DAXX", "DBN1", "DBT", "DCAF8", "DCK", "DCPS", "DCTN1", "DCUN1D1", "DDOST", "DDRGK1", "DDX10", "DDX3X", "DDX41", "DDX5", "DDX6", "DEK", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHTKD1", "DHX16", "DHX30", "DHX37", "DHX38", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIS3", "DKC1", "DLD", "DLG3", "DLST", "DNAAF5", "DNAJB1", "DNAJB11", "DNAJB6", "DNAJC13", "DNAJC2", "DNAJC3", "DNM1L", "DNM2", "DNMT1", "DOCK7", "DPF2", "DPH1", "DPM1", "DSC3", "DSE", "DSG2", "DSP", "DST", "DYM", "DYNC1H1", "DYNC1I2", "DYNC2H1", "DYNLL1", "EARS2", "ECE1", "ECHS1", "EDC3", "EED", "EEF1A2", "EEF2", "EFL1", "EFTUD2", "EI24", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2S2", "EIF2S3", "EIF3E", "EIF3F", "EIF3H", "EIF4A2", "EIF4A3", "EIF4E", "EIF4G1", "EIF4H", "EIF5A", "ELAC2", "ELP1", "ELP2", "ELP3", "EMC1", "EMD", "EMG1", "EML4", "ENO1", "ENO2", "EPB41", "EPB41L3", "EPHA7", "EPHX1", "EPPK1", "EPRS", "EPS15", "ERAL1", "ERC1", "ERCC2", "ERCC3", "ERGIC1", "ERLIN1", "ERLIN2", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXOC8", "EXOSC2", "EXOSC3", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "FADS2", "FAF1", "FAH", "FAM120A", "FAM3C", "FAM50A", "FANCG", "FANCI", "FAR1", "FARSB", "FASN", "FASTKD2", "FDPS", "FDXR", "FECH", "FEN1", "FGFR1OP", "FH", "FHL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP1A", "FKBP5", "FKBP8", "FKRP", "FLAD1", "FLNA", "FLNB", "FLNC", "FMR1", "FNTA", "FOXRED1", "FSCN1", "FTO", "FUBP1", "FUCA1", "FUS", "G6PD", "GAA", "GAL", "GALK1", "GALM", "GALNS", "GALNT2", "GAMT", "GANAB", "GAPDH", "GARS", "GART", "GATAD2B", "GATB", "GBA", "GCDH", "GCLC", "GCLM", "GDAP2", "GDI1", "GEMIN4", "GFM1", "GFPT1", "GGCX", "GGPS1", "GIGYF2", "GIPC1", "GLA", "GLB1", "GLDC", "GLMN", "GLO1", "GLRX5", "GLS", "GM2A", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI3", "GNAO1", "GNPAT", "GNS", "GOLGA5", "GOPC", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPHN", "GPI", "GPRASP2", "GPT2", "GRB2", "GSK3A", "GSK3B", "GSR", "GSS", "GSTM3", "GSTZ1", "GTF2H1", "GTF2I", "GTPBP3", "GUF1", "GUSB", "GYG1", "GYS1", "H3-3A*", "H4C1*", "HADH", "HADHA", "HADHB", "HAX1", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HELLS", "HERC2", "HEXA", "HEXB", "HIBCH", "HIP1", "HIP1R", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLCS", "HMBS", "HMGA1", "HMGB3", "HMGCL", "HMGCR", "HMMR", "HMOX1", "HNRNPA1", "HNRNPA2B1", "HNRNPDL", "HNRNPH2", "HNRNPK", "HNRNPU", "HOOK3", "HPRT1", "HPS6", "HSD17B10", "HSD17B4", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA2", "HSPA4", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HUWE1", "HYOU1", "IARS", "IARS2", "IBA57", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IFT27", "IFT52", "IGBP1", "IGF2R", "IGHMBP2", "IKBKB", "ILF3", "ILK", "IMPAD1", "IMPDH1", "IMPDH2", "INF2", "INTS1", "IPO7", "IQCB1", "IRF2BPL", "IRS4", "ITGA2", "ITGAV", "ITGB1", "ITPA", "IVD", "JAGN1", "JAM3", "JUP", "KARS", "KCTD21", "KDM1A", "KDM3B", "KDSR", "KEAP1", "KIDINS220", "KIF11", "KIF20B", "KIF22", "KIF2A", "KIF2C", "KIF4A", "KIF5B", "KIFBP", "KLC2", "KNSTRN", "KTN1", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP2", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LGALS3", "LGALS3BP", "LGMN", "LIPA", "LMAN2L", "LMNA", "LMNB1", "LMNB2", "LONP1", "LRBA", "LRPPRC", "LRSAM1", "LSS", "LTA4H", "LZTFL1", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAGED2", "MAGT1", "MAN2B1", "MAP1A", "MAP1B", "MAP2K1", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MARS", "MARS2", "MASTL", "MATR3", "MBOAT7", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM5", "MCM7", "MCTS1", "MDC1", "MDH1", "MDH2", "MECP2", "MECR", "MED1", "MED17", "MED23", "MED25", "MESD", "MFN2", "MFSD8", "MICU1", "MID1", "MIF", "MIPEP", "MKI67", "MMAB", "MOCOS", "MOCS1", "MOGS", "MPDU1", "MPI", "MPV17", "MRE11", "MRPL12", "MRPL3", "MRPL44", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS28", "MRPS34", "MRPS7", "MSH2", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MYH10", "MYH14", "MYH9", "MYO6", "NAA10", "NAA15", "NADSYN1", "NAGLU", "NAMPT", "NANS", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCKIPSD", "NCSTN", "ND1", "ND5", "NDE1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA4", "NDUFA6", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFB11", "NDUFB3", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NEFL", "NEK9", "NFU1", "NHLRC2", "NHP2", "NIPBL", "NISCH", "NME1", "NME2", "NNT", "NONO", "NOP10", "NOP56", "NOTCH2", "NPC1", "NPC2", "NPM1", "NRP1", "NSD1", "NSD2", "NSD3", "NSDHL", "NSMCE3", "NSUN2", "NSUN5", "NT5C2", "NT5C3A", "NTHL1", "NUBPL", "NUCB2", "NUDT1", "NUMA1", "NUP107", "NUP133", "NUP155", "NUP160", "NUP188", "NUP205", "NUP214", "NUP37", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NXN", "OAT", "OBSL1", "OCLN", "OCRL", "OGDH", "OGT", "OPA1", "OPA3", "OSBPL2", "OXCT1", "P3H1", "P4HA2", "P4HB", "PABPC1", "PABPN1", "PAF1", "PAFAH1B1", "PAFAH1B2", "PANX1", "PARK7", "PARN", "PARP1", "PARP2", "PAX6", "PBRM1", "PC", "PCBD1", "PCBP1", "PCCA", "PCCB", "PCM1", "PCNA", "PDAP1", "PDCD4", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDK1", "PDK3", "PDP1", "PDSS1", "PDSS2", "PDXK", "PEPD", "PET100", "PEX14", "PEX19", "PEX5", "PEX6", "PFKM", "PFN1", "PGK1", "PGM1", "PGM3", "PHB", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4KA", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIN1", "PISD", "PKM", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLS1", "PLS3", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNP", "PNPLA6", "PNPO", "PNPT1", "POGZ", "POLA1", "POLD1", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR3A", "POMGNT2", "POP1", "POR", "PPA2", "PPIB", "PPIF", "PPOX", "PPP1CB", "PPP1R12A", "PPP2R1A", "PPP2R5D", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PQBP1", "PRC1", "PRCC", "PRDX2", "PRDX4", "PRDX5", "PREPL", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PROCR", "PRPF3", "PRPF31", "PRPF4", "PRPF6", "PRPF8", "PRPS1", "PSAP", "PSAT1", "PSIP1", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMD12", "PSMD4", "PTDSS1", "PTPN11", "PTPN23", "PTRH2", "PUF60", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "RAB10", "RAB11B", "RAB18", "RAB23", "RAB3GAP2", "RAB7A", "RAB8A", "RABEP1", "RABL3", "RAC1", "RAD21", "RAD23B", "RANBP2", "RANBP3", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RBBP4", "RBM10", "RBM12", "RBM15", "RBM28", "RBM6", "RBM7", "RBMX", "RDH11", "RDX", "REEP2", "REPS1", "RFC1", "RFC2", "RFK", "RFT1", "RHEB", "RINT1", "RIPK1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF213", "ROCK1", "ROCK2", "RPA2", "RPL10", "RPL11", "RPL13", "RPL15", "RPL18", "RPL21", "RPL22", "RPL26", "RPL27", "RPL3", "RPL35", "RPL35A", "RPL5", "RPN1", "RPS10", "RPS15", "RPS15A", "RPS17", "RPS19", "RPS2", "RPS23", "RPS24", "RPS28", "RPS29", "RPS3", "RPS6KA1", "RPS6KA3", "RPS7", "RPSA", "RRM1", "RRM2", "RRM2B", "RTN2", "RTN4IP1", "SAMHD1", "SAR1B", "SARS", "SART1", "SBDS", "SC5D", "SCARB2", "SCO1", "SCO2", "SCRIB", "SCYL1", "SDHA", "SDHB", "SEC23A", "SEC23B", "SEC31A", "SEC61A1", "SEC63", "SELENBP1", "SEPT2", "SEPT9", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF3B1", "SFPQ", "SFXN4", "SGPL1", "SH3GL1", "SHOC2", "SIGMAR1", "SIN3A", "SKIV2L", "SKP2", "SLC12A2", "SLC16A1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC33A1", "SLC38A2", "SLC39A14", "SLC3A2", "SLC9A3R1", "SMARCA4", "SMARCAD1", "SMARCB1", "SMARCC2", "SMARCD1", "SMARCE1", "SMC1A", "SMC3", "SMCHD1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SNAP29", "SND1", "SNRNP200", "SNRPE", "SNX3", "SOAT1", "SOD2", "SON", "SORD", "SPART", "SPAST", "SPATA5", "SPECC1", "SPEN", "SPR", "SPTAN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SRP54", "SRP72", "SRSF2", "SRSF3", "SSB", "SSR4", "STAG1", "STAG2", "STAMBP", "STARD3", "STAT1", "STAT3", "STMN1", "STRAP", "STRN", "STT3A", "STT3B", "STUB1", "STX5", "STXBP2", "SUCLA2", "SUCLG1", "SUZ12", "SV2A", "SYNE2", "TAF15", "TALDO1", "TAP1", "TARDBP", "TARS", "TARS2", "TBC1D4", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TCEA1", "TCOF1", "TCTN3", "TECR", "TELO2", "TFAM", "TFG", "TFRC", "THOC2", "THOC6", "TIMM17A", "TIMM22", "TIMM50", "TIMMDC1", "TJP2", "TK1", "TKFC", "TKT", "TMCO1", "TMEM126B", "TMEM165", "TMEM199", "TMEM230", "TMEM38B", "TMEM43", "TMEM70", "TMF1", "TMTC3", "TMX2", "TNPO3", "TOE1", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TP53", "TP53BP1", "TPD52", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPR", "TPRKB", "TPX2", "TRAPPC11", "TRIM24", "TRIM25", "TRIM27", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIT1", "TRMT10C", "TRMU", "TRRAP", "TSFM", "TSG101", "TTC19", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUFM", "TWF1", "TWNK", "TXLNA", "TXNDC15", "TXNRD1", "TYMS", "U2AF1", "UBA1", "UBA5", "UBE2N", "UBIAD1", "UBQLN4", "UBR5", "UBTF", "UFC1", "UFSP2", "UGCG", "UGDH", "UGP2", "UMPS", "UNC119", "UNG", "UPF3B", "UQCC2", "UQCRB", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USP8", "USP9X", "UTP4", "VANGL1", "VAPB", "VARS1", "VARS2", "VCL", "VCP", "VIM", "VKORC1L1", "VPS13A", "VPS13D", "VPS16", "VPS33A", "VPS33B", "VPS35", "VPS45", "VPS4A", "VPS51", "VPS53", "VRK1", "WARS", "WARS2", "WASHC4", "WASHC5", "WBP2", "WDR1", "WDR34", "WDR36", "WDR4", "WDR45B", "WDR5", "WDR73", "WFS1", "WNK1", "WRN", "XPNPEP3", "XPO1", "XRCC1", "XRCC5", "XRCC6", "YARS", "YARS2", "YBX1", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAZ", "YY1", "ZC3H14", "ZCCHC8", "ZMPSTE24", "ZMYM2", "ZNF644"], "leading_proteins": ["AARS2", "ABAT", "ABCB6", "ABCB7", "ABCD4", "ABHD12", "ACADVL", "ACOX1", "ACTN1", "ACTN4", "ADA", "ADD3", "ADK", "AGPS", "AIFM1", "AKT1", "AKT2", "ANKLE2", "APP", "ARIH1", "ATP2A2", "ATP5A1", "ATP6", "ATP6AP2", "B3GALT6", "B4GAT1", "BBS4", "BCR", "BICD2", "CANT1", "CAPN5", "CASK", "CCDC22", "CD320", "CDC45", "CDH2", "CEP250", "CEP290", "CERS1", "CHMP1A", "CHST14", "CLCN7", "CLN5", "CLN6", "CLPP", "CNNM4", "COA3", "COPB2", "COX15", "COX2", "CPT2", "CRTAP", "CTH", "CTSA", "CYFIP2", "CYP51A1", "DCAF8", "DCTN1", "DDRGK1", "DHCR24", "DHCR7", "DIABLO", "DIAPH3", "DOCK7", "DYM", "ECE1", "EED", "EMD", "EPS15", "EWSR1", "EXOSC2", "FECH", "FKBP14", "FKRP", "FLAD1", "FNTA", "FOXRED1", "FUCA1", "FUS", "GAA", "GAL", "GLA", "GLB1", "GNS", "GSR", "GUSB", "GYS1", "HCCS", "HIP1", "IDH2", "IFT52", "IMPAD1", "INTS1", "IQCB1", "JAM3", "KARS", "KIF11", "KNSTRN", "LAMB1", "LBR", "LMNA", "LMNB2", "M6PR", "MAD1L1", "MAN2B1", "MBOAT7", "MED25", "MFSD8", "MID1", "MPV17", "MRPS16", "MSN", "MYH10", "MYH14", "MYH9", "NAA10", "NAGLU", "NBAS", "NCAPD2", "NCAPH", "NCSTN", "ND1", "NDUFB3", "NDUFS2", "NDUFS6", "NDUFS7", "NEFL", "NNT", "NPC1", "NPC2", "NSD1", "NSD2", "NSD3", "NUP188", "NUP37", "NUP93", "OCLN", "OPA1", "OSBPL2", "PDHB", "PIBF1", "PIGT", "PLD3", "POMGNT2", "PPOX", "PPT1", "PREPL", "PRKAG1", "PRKRA", "PSAP", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PUF60", "RAPGEF2", "RMND1", "RNASET2", "ROCK1", "ROCK2", "RPS23", "RRM2B", "RTN2", "SCARB2", "SDHA", "SEC23B", "SET", "SIGMAR1", "SLC12A2", "SLC16A1", "SLC25A10", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A26", "SLC25A42", "SLC2A1", "SLC33A1", "SMC3", "SMCHD1", "SNX3", "SORD", "SPART", "SPATA5", "SPECC1", "SPTAN1", "STAG1", "SV2A", "SYNE2", "TAF15", "TBC1D4", "TFG", "TFRC", "TMEM165", "TMEM70", "TMTC3", "TPM1", "TPM3", "TPP1", "TPR", "TRIM27", "TRIM32", "TTC19", "TUBGCP2", "TWNK", "UBIAD1", "UFSP2", "UGCG", "UNC119", "UQCC2", "UQCRC2", "VIM", "VKORC1L1", "WBP2", "WFS1", "XPNPEP3", "ZMPSTE24"]} \ No newline at end of file diff --git a/protein_atlas_molecular_function/advanced/idx2term.json 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100644 index 0000000000000000000000000000000000000000..f7df4b53999ac3fc9cd3508dcb47e862b10ae2d9 --- /dev/null +++ b/protein_atlas_molecular_function/df_merge.tsv @@ -0,0 +1,8 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Protease 27 89 3.0778847922832253 0.0020847549511222 20.788834951456312 82.44417475728156 1.1215350835872162 0.3507517256058336 6.07090559629836 8.079357013764625 1.4678877461728397 0.3691345771929886 0.2220574737531545 0.0043476415853434 0.0062484223330755 1.1054172873833022e-05 5.143057210875849e-05 +Receptor 14 43 2.891009415115238 0.0038400661583655 13.475728155339803 38.71116504854369 1.6655960679271569 0.1791616261110447 5.431559450288914 6.105192092581698 1.9169648296245776 0.2753083483896962 0.0284635326709435 0.1129146346736405 0.2144950360506774 0.257017205453369 0.2362547174538379 +Carboxypeptidase 4 6 2.242262867479974 0.0249443881311615 3.1359223300970873 6.150485436893204 0.9957728306848488 0.1212034427500092 1.2071674596015187 0.4479454254223922 1.8250051834990677 0.2074401112551974 0.0160721278711563 0.0021914548918381 0.0003495610743441 0.000366006536683 0.0005338561483377 +Glycosidase 9 20 2.241446603636668 0.024997160623237 7.798543689320389 18.135922330097088 0.5112745472223946 0.1951515073440806 2.9064203812520417 1.9684331341643595 1.9501681029822375 0.2619382904734375 1.0 1.0 0.3376050929703735 0.0005352167677164 3.042567652627972e-05 +Metalloprotease 7 28 2.1957792202924544 0.0281077496826214 8.160194174757281 26.429611650485437 1.390302281711237 0.2661274848815638 3.192614043118206 1.543038499308978 1.1108461579919544 0.309446154241223 1.0 0.0303491574999332 0.0176589935056828 0.0004601600061541 0.0017963005545976 +Guanine-nucleotide releasing factor 9 20 2.051919905469365 0.0401774470071132 3.1990291262135924 16.21359223300971 0.5547832364838432 0.4500807259710942 2.2927066780931713 4.394171968646284 0.9520620002287806 0.2997519109124153 1.0 1.0 0.0311592891852558 0.1843027980199457 0.154794926175166 +Muscle protein 2 7 2.0396153520438154 0.0413886517700317 2.395631067961165 5.79126213592233 0.1338245975855889 0.4297267356278353 1.4112173151187923 1.0428309859537837 1.1380106971522683 0.3003044609278026 1.0 1.0 1.0 0.0757571260003459 0.0621142898948071 diff --git a/protein_atlas_molecular_function/metrics.json b/protein_atlas_molecular_function/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..ecef0291487071474d1fc1335dfc14203e05ab75 --- /dev/null +++ b/protein_atlas_molecular_function/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 97, + "title": "Average number of proteins per term", + "value": 42.55670103092783 +} \ No newline at end of file diff --git a/protein_atlas_molecular_function/paths.json b/protein_atlas_molecular_function/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..8effa564ff62150ad0137c537d7288e9699f1989 --- /dev/null +++ b/protein_atlas_molecular_function/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_molecular_function/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_molecular_function/result.tsv b/protein_atlas_molecular_function/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..3cca0bbba3903bba3aa82fdf928e5c1298400137 --- /dev/null +++ b/protein_atlas_molecular_function/result.tsv @@ -0,0 +1,37 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Protease 0.5233669574085239 3.0778847922832253 0.0020847549511222 0.1832582377292518 0.0224690255843176 89 P42785,Q4J6C6,O14773,P28072,Q8TCT8,P55786,Q9HB40,Q9UIQ6,P28074,P42892,P10619,O75976,O15484,P78536,Q9H300,Q9H3G5,Q96K76,P52888,Q9NQH7,P17655,Q9NZ08,Q93009,Q16740,Q99538,Q99436,O75844,Q9UPT9 27 +Receptor 0.5932749174526566 2.891009415115238 0.0038400661583655 0.3114748548244845 0.0310405347801212 43 P11717,Q99720,Q14108,P20645,O15118,O15173,Q8WTV0,P02786,O75787,Q14739,Q5KU26,Q99523,P30825,P10586 14 +Carboxypeptidase 0.8912444379499007 2.242262867479974 0.0249443881311615 0.913731854645769 0.1303127668797557 6 Q9HB40,P42785,O75976,P10619 4 +Glycosidase 0.6211534863850386 2.241446603636668 0.024997160623237 0.9141835780944492 0.1303127668797557 20 P16278,O00754,P04066,Q9BTY2,O60476,P10253,O60502,P54802,P06280 9 +Metalloprotease 0.5787889183667845 2.1957792202924544 0.0281077496826214 0.9370555332944356 0.1363225859607139 28 P52888,Q9UIQ6,Q9NZ08,O75976,P42892,P78536,P55786 7 +Threonine protease 0.9590659340659342 2.1039002557374764 0.0353871486810655 0.9696439519028772 0.1560251555483343 3 Q99436,P28074 2 +Guanine-nucleotide releasing factor 0.5905269552168387 2.0519199054693655 0.0401774470071132 0.98127067247997 0.1602010846572525 20 Q02818,Q96N67,Q92888,A4D1U4,Q9Y4G8,O75592,P11274,P80303,Q14185 9 +Muscle protein 0.7957078076798371 2.0396153520438154 0.0413886517700317 0.983429756244278 0.1602010846572525 7 P67936,P09493 2 +Cytokine 0.9181472664735412 2.038712010786999 0.0414787783288363 0.9835801924458272 0.1602010846572525 4 P14174 1 +Serine protease inhibitor 0.8119039801776062 1.9224628342038612 0.0545475457961903 0.9956643893762412 0.1824521359389815 6 P05067 1 +Porin 0.8545283315463459 1.7937142338709169 0.0728587922315089 0.9993496445775384 0.2139149936125392 4 P21796 1 +Glycosyltransferase 0.4621140007351098 1.7523798269919149 0.0797085178607608 0.9996832154216048 0.2147701731248278 41 Q68CQ7,Q96L58,P43490,Q16739,O43505,Q8NAT1,P15291,Q13126,O60512,P13807 10 +Myosin 0.6769196525830136 1.7372213745927252 0.0823481034785738 0.9997602477171714 0.2158855685789637 9 P35579,P35580 2 +Heparin-binding 0.6919522064298038 1.691330361694449 0.0907737243447885 0.9999020099782988 0.2257705451652434 8 P05067 1 +Acyltransferase 0.4654539156650817 1.676215574569728 0.0936959746023733 0.9999282917428676 0.2272127384107553 36 Q8NCC3,Q9HCL2,Q9BWD1 3 +Protease inhibitor 0.6560668312671665 1.6383361001312515 0.1013516009530617 0.9999685072141684 0.2397830559133411 9 P05067 1 +Endonuclease 0.5020252651909616 1.4839334222440348 0.1378265840947725 0.9999994341792192 0.292649841057741 20 Q9UQ84,Q8N2A8 2 +Serine protease 0.5682404765414518 1.3542908021179214 0.175643619452491 0.9999999927028148 0.3407486217378327 11 Q16740,O14773,Q4J6C6 3 +Calmodulin-binding 0.4171121242445543 1.2760548999789576 0.2019361127788721 0.9999999996854766 0.3766885180682807 36 P35579,Q14012,Q15051,P35580,Q13555,Q86VI3,Q7Z406,Q01082,P32929,Q13813,O14936 11 +Aminopeptidase 0.5031538385869717 1.0803877965582576 0.2799695278185448 0.9999999999999856 0.4937644399708881 13 Q9UIQ6,Q9NZ08,P55786 3 +Host cell receptor for virus entry 0.4481641761835676 1.031266512858157 0.3024158573555398 0.9999999999999992 0.514637511640129 17 Q8WTV0,Q14108,O15118 3 +Translocase 0.4034803390782904 0.9360087528590468 0.3492686811403933 1.0 0.5700548746574399 28 P03886,Q13423,P16615,O75306,O75251,Q9HD20 6 +Exonuclease 0.4156011473507178 0.906730889596608 0.3645491243251144 1.0 0.5766790489191689 19 Q9UQ84 1 +Thiol protease 0.3893114099597481 0.8843812323572113 0.3764904506276696 1.0 0.5766790489191689 30 Q96RU2,Q96K76,Q86UV5,P17655,Q8NB14,Q93009,O15484,Q99538,Q9NUQ7,Q9UPT9 10 +Tyrosine-protein kinase 0.5634495912394798 0.8769951555289113 0.3804892693899671 1.0 0.5766790489191689 6 Q15375 1 +Nuclease 0.3631871753952451 0.8364191103871648 0.4029191653496196 1.0 0.5921690763471682 37 Q9UQ84,Q8N2A8,Q8IV08 3 +Lyase 0.3368818601062207 0.7770574513242792 0.4371248755891284 1.0 0.6235457784139038 48 P22830,P12956,O00584 3 +Chromatin regulator 0.3182030441412015 0.7187940883215541 0.4722678006649392 1.0 0.653297150514072 97 Q8NB78,P46379,O75530,O96028,Q9Y2K7,Q9UPT9 6 +Actin capping 0.4868459046763889 0.6841843886389257 0.4938587389338345 1.0 0.6653374677303048 7 Q13813 1 +Motor protein 0.3433082320631916 0.5926121424666381 0.5534407510168791 1.0 0.7157833713151636 32 P35579,P35580,P33176,Q9Y496,O94832,Q7Z406,Q9UQ16,Q02241,P52732,Q07866,O95239,Q14807 12 +Prenyltransferase 0.4661856803172957 0.3376851008061726 0.7356005037371716 1.0 0.9032056818038688 4 P49354,Q9Y5Z9 2 +Transducer 0.3568289742544366 0.3089766677727604 0.757339275432771 1.0 0.9096883140542578 10 P02786,Q9UBI6 2 +Developmental protein 0.2802266086379764 0.2730044212960767 0.7848498169302713 1.0 0.9172341234004376 92 Q13045,Q8NB78,Q14012,Q92520,P51114,O94813,Q07820,Q16352,Q96N67,P48681,Q99426,Q96EK5,Q9BY67,Q16527,Q15375,Q9NXR1,Q8NB90,Q9NRZ9,Q9Y4G8,Q7L576,P31749,Q96PU8,Q13555,Q5T9L3,Q99523,Q9UJC3,P31751,Q93009,Q9H2U1,Q9UPN4,Q9NUN5,O75175 32 +Oxidoreductase 0.2670017458473902 0.1524227213104569 0.8788535374378759 1.0 0.9798711854192408 182 Q8NB78,P30837,O94788,P30519,Q9UBM7,P00390,Q9Y2K7,Q8N8N7,Q00796,Q9UHG3,Q9Y6N5,P49748,Q15392,O95831,O75251,Q14739,P50336,Q16850,Q8NBX0,Q8N0U8,Q7LG56,P31350,O15254,Q8IXB1,P48735,Q96CU9,O00625 27 +DNA-directed DNA polymerase 0.365759824127521 0.1162562420991712 0.9074494641352472 1.0 1.0 4 P09884,Q07864,P28340 3 +Topoisomerase 0.296978021978024 0.0432183565318169 0.9655274723630962 1.0 1.0 3 P11388,P11387 2 diff --git a/protein_atlas_molecular_function/selections.json b/protein_atlas_molecular_function/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..8509ab15031820fe801ce5524a472d3987624569 --- /dev/null +++ b/protein_atlas_molecular_function/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin capping", "Actin-binding", "Activator", "Acyltransferase", "Allosteric enzyme", "Aminoacyl-tRNA synthetase", "Aminopeptidase", "Aminotransferase", "Antibiotic", "Antimicrobial", "Antioxidant", "Aspartyl protease", "Blood group antigen", "Calcium channel", "Calmodulin-binding", "Carboxypeptidase", "Chaperone", "Chloride channel", "Chromatin regulator", "Cytokine", "DNA-binding", "DNA-directed DNA polymerase", "Decarboxylase", "Developmental protein", "Dioxygenase", "Dipeptidase", "Elongation factor", "Endonuclease", "Excision nuclease", "Exonuclease", "Fungicide", "GTPase activation", "Glycosidase", "Glycosyltransferase", "Growth factor", "Guanine-nucleotide releasing factor", "Helicase", "Heparin-binding", "Hormone", "Host cell receptor for virus entry", "Hydrolase", "IgE-binding protein", "Initiation factor", "Integrin", "Ion channel", "Isomerase", "Kinase", "Ligase", "Lyase", "Metalloenzyme inhibitor", "Metalloprotease", "Methyltransferase", "Mitogen", "Monooxygenase", "Motor protein", "Multifunctional enzyme", "Muscle protein", "Myosin", "Neuropeptide", "Nuclease", "Nucleotidyltransferase", "Oxidoreductase", "Peroxidase", "Phospholipase A2 inhibitor", "Porin", "Potassium channel", "Prenyltransferase", "Protease", "Protease inhibitor", "Protein kinase inhibitor", "Protein phosphatase", "Protein phosphatase inhibitor", "Protein synthesis inhibitor", "RNA-binding", "Receptor", "Repressor", "Ribonucleoprotein", "Ribosomal protein", "Rotamase", "Serine esterase", "Serine protease", "Serine protease inhibitor", "Serine/threonine-protein kinase", "Signal transduction inhibitor", "Thiol protease", "Thiol protease inhibitor", "Threonine protease", "Topoisomerase", "Transducer", "Transferase", "Translational shunt", "Translocase", "Tumor antigen", "Tyrosine-protein kinase", "Voltage-gated channel", "rRNA-binding", "tRNA-binding"], "available_proteins": ["AAK1", "AAMP", "AARS", "AARS2", "AASDHPPT", "AASS", "ABAT", "ABCB1", "ABCB6", "ABCC1", "ABCC4", "ABCE1", "ABCF1", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABR", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR2", "ACTR3", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADSL", "ADSS", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT2", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "AMFR", "AMPD2", "ANKHD1", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA2", "ANXA3", "APBB1", "APEH", "APEX1", "APLP2", "APOBEC3C", "APP", "APRT", "AQR", "ARFGAP1", "ARFGAP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL8B", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "AS3MT", "ASAH1", "ASCC3", "ASNA1", "ASNS", "ASPH", "ATAD1", "ATAD2", "ATF7", "ATG3", "ATG4B", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5B", "ATP6AP2", "ATP6V1A", "ATP6V1B2", "ATP6V1E1", "ATPAF2", "ATRX", "AURKA", "AURKB", "B3GALT6", "B3GAT3", "B4GALT1", "B4GALT3", "B4GAT1", "BABAM2", "BAG2", "BAG3", "BAG4", "BAG5", "BAG6", "BANF1", "BAP18", "BAZ1B", "BAZ2A", "BCAT2", "BCKDK", "BCLAF1", "BCR", "BCS1L", "BEND3", "BIRC6", "BLM", "BLMH", "BLVRA", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BRD4", "BRIP1", "BSG", "BTF3", "BUB1B", "BUD23", "BZW1", "BZW2", "C12orf43", "CABIN1", "CAD", "CADM1", "CALCOCO1", "CALD1", "CALR", "CAMK1", "CAMK2G", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX3", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC47", "CCDC51", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD320", "CDC37", "CDC42", "CDC42BPB", "CDC5L", "CDC7", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPU", "CEP131", "CEP290", "CEPT1", "CERS1", "CERS2", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHKA", "CHMP1A", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIRBP", "CKB", "CKMT1A*", "CLCC1", "CLGN", "CLIC1", "CLIC4", "CLPB", "CLPP", "CLPTM1", "CLPX", "CLU", "CLUH", "CMAS", "CMPK1", "CMTR1", "CNDP2", "CNN3", "CNOT1", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "COASY", "COLEC12", "COLGALT1", "COMT", "COMTD1", "COPA", "COPS5", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX2", "COX4I1", "CPD", "CPNE1", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CROT", "CRYZ", "CS", "CSDE1", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSRP2", "CSTB", "CSTF2", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNB1", "CTPS1", "CTPS2", "CTSA", "CTSC", "CUL5", "CXADR", "CXorf57", "CYB5R3", "CYC1", "CYFIP1", "CYP20A1", "CYP51A1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTPP1", "DCXR", "DDB1", "DDI2", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIAPH1", "DICER1", "DIEXF", "DIS3", "DKC1", "DLAT", "DLD", "DLST", "DMAP1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DRG1", "DRG2", "DSE", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EDC3", "EDF1", "EDRF1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1G", "EEF2", "EFL1", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMOD2", "ELP3", "EMD", "EMG1", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPHA7", "EPHX1", "EPHX2", "EPRS", "ERAL1", "ERAP1", "ERAP2", "ERCC2", "ERCC3", "ERCC6L", "ERMP1", "ERO1A", "ERO1B", "ERP44", "ESD", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "F11R", "FADS2", "FAH", "FAHD1", "FAM120A", "FAM173A", "FAM208A", "FAM213A", "FAM3C", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEN1", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FMR1", "FN3KRP", "FNTA", "FOXRED1", "FRG1", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCDH", "GCLC", "GCN1", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN5", "GFM1", "GFPT1", "GGCT", "GGCX", "GGH", "GGPS1", "GLA", "GLB1", "GLDC", "GLO1", "GLS", "GLT8D1", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNPAT", "GNPDA1", "GNS", "GOT1", "GOT2", "GPAM", "GPAT4", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR89B", "GPT2", "GPX8", "GRHPR", "GRPEL1", "GRSF1", "GSK3A", "GSK3B", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2F1", "GTF2F2", "GTF2I", "GTF3C1", "GTF3C3", "GTF3C4", "GTF3C5", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL3", "HDLBP", "HEATR1", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HIBADH", "HIBCH", "HIF1AN", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HOOK1", "HP1BP3", "HPRT1", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDI1", "IFIT5", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INF2", "INPP4A", "INTS11", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRS4", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITPK1", "IVD", "JMJD6", "KARS", "KAT7", "KATNA1", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KHDRBS1", "KHSRP", "KIAA0391", "KIAA1147", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KRR1", "KYAT3", "L2HGDH", "LACTB", "LAMP1", "LANCL1", "LAP3", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD3", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LMBRD1", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRPAP1", "LRPPRC", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LUC7L3", "LYAR", "LYPLA1", "M6PR", "MACF1", "MAEA", "MAGED2", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1S", "MAP2K1", "MAP3K7", "MAPK1", "MAPK14", "MAPK3", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MATR3", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCTS1", "MCU", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFN2", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MID1", "MIF", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOCOS", "MOCS1", "MOGS", "MON1A", "MORF4L1", "MORF4L2", "MOV10", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPRIP", "MPST", "MRE11", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS6", "MRPS7", "MRPS9", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MTA1", "MTA2", "MTAP", "MTERF3", "MTF2", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTR", "MUT", "MVD", "MYBBP1A", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L4", "NARS", "NAT10", "NAXE", "NCBP3", "NCEH1", "NCL", "NCOA5", "ND1", "ND5", "NDE1", "NDUFAF2", "NDUFAF4", "NDUFAF7", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NEK3", "NEK9", "NELFA", "NELFCD", "NELFE", "NES", "NFS1", "NHP2", "NIFK", "NIP7", "NIPBL", "NISCH", "NIT2", "NKRF", "NKTR", "NLN", "NME1", "NME2", "NMT1", "NNT", "NOB1", "NOC2L", "NOL11", "NOL6", "NOL8", "NOL9", "NONO", "NOP10", "NOP2", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NRDC", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUCB1", "NUCB2", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUP153", "NUP98", "NXF1", "NXN", "OAT", "OCRL", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "ORC3", "OTUB1", "OXCT1", "OXSR1", "P3H1", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAX6", "PAXBP1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCK2", "PCMT1", "PCNA", "PCYOX1", "PCYOX1L", "PDCD4", "PDCL3", "PDE12", "PDHA1", "PDHB", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM7", "PDP1", "PDRG1", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PEBP1", "PECR", "PELO", "PELP1", "PEPD", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB2", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIGG", "PIGK", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLD1", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR2B", "POLR2G", "POLR3A", "POLR3C", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R14B", "PPP1R8", "PPP3CA", "PPP5C", "PPP6C", "PPT1", "PPT2", "PPWD1", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKCD", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF31", "PRPF4B", "PRPF8", "PRPS1", "PSAT1", "PSIP1", "PSMB5", "PSMB6", "PSMB7", "PSMD10", "PSMD14", "PSMD9", "PSME4", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "RAB10", "RAB11B", "RAB18", "RAB1A", "RAB1B", "RAB23", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RABGAP1", "RABGGTA", "RABGGTB", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD50", "RALA", "RALY", "RANBP1", "RANBP2", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC3", "RFK", "RFX1", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIOK2", "RIOX2", "RIPK1", "RNASEH2A", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPF1", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPP14", "RPP30", "RPP40", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1B", "RRP7A", "RRP8", "RRP9", "RSF1", "RTCA", "RTCB", "RTF1", "RTRAF", "RUVBL1", "RUVBL2", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAP18", "SAP30", "SAP30BP", "SARM1", "SARNP", "SARS", "SARS2", "SART3", "SC5D", "SCAF1", "SCAF4", "SCAF8", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCLY", "SCML2", "SCO1", "SCO2", "SCP2", "SCPEP1", "SCRIB", "SCYL1", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC61A1", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3B1", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SGF29", "SGPL1", "SGTA", "SHMT1", "SHMT2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SLC1A5", "SLC27A4", "SLC7A1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMCHD1", "SMG1", "SMN1*", "SMPD4", "SMS", "SMYD3", "SND1", "SNRNP200", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SOAT1", "SOD2", "SON", "SORD", "SORT1", "SPAST", "SPATA5", "SPCS2", "SPCS3", "SPEN", "SPHK2", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSRP1", "STAMBP", "STAT1", "STAT3", "STAU1", "STK26", "STK4", "STMN1", "STRBP", "STRN", "STT3A", "STT3B", "STUB1", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SULT2A1", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF6", "SUZ12", "SYNCRIP", "SYNE2", "TAF15", "TALDO1", "TAMM41", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBPL1", "TCEA1", "TCERG1", "TCF25", "TCP1", "TDRKH", "TECR", "TERF2IP", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFRC", "THAP11", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD3", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TK1", "TKFC", "TKT", "TLE3", "TM7SF2", "TMCO1", "TMEM109", "TMEM126B", "TMEM206", "TMEM38B", "TMF1", "TMOD1", "TMOD3", "TMTC3", "TMX3", "TOMM22", "TOMM34", "TOMM40", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TRA2A", "TRA2B", "TRAP1", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT1L", "TRMT2A", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSN", "TSNAX", "TSTA3", "TTF2", "TTK", "TTYH3", "TUFM", "TWF1", "TWF2", "TWNK", "TXNDC12", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA6", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE3C", "UBE4A", "UBE4B", "UBIAD1", "UBLCP1", "UBR4", "UBR5", "UBR7", "UBTF", "UCHL5", "UCK2", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCRFS1", "UROD", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTRN", "UXS1", "UXT", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VIRMA", "VKORC1L1", "VPS4A", "VPS4B", "VPS72", "VRK1", "VRK2", "WARS", "WARS2", "WASF2", "WDHD1", "WDR1", "WDR18", "WDR43", "WDR5", "WLS", "WNK1", "WRN", "WTAP", "XPNPEP1", "XPNPEP3", "XPO1", "XPO5", "XPOT", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF2", "YTHDF3", "YY1", "ZADH2", "ZC3H14", "ZC3HAV1", "ZCCHC11", "ZCCHC3", "ZCRB1", "ZDHHC13", "ZFR", "ZMAT2", "ZMPSTE24", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF638", "ZNF644", "ZNF687"], "leading_proteins": ["ACADVL", "ACAT2", "ACOX3", "ADAM17", "AIFM1", "AKT1", "AKT2", "ALDH1A2", "ALDH1B1", "APP", "ARHGEF1", "ATP13A1", "ATP2A2", "ATP6AP2", "B3GALT6", "B4GALT1", "B4GALT3", "B4GAT1", "BAG6", "BCR", "CADM1", "CAMK1", "CAMK2G", "CAPN2", "CAPN5", "CASK", "CEP131", "CLPP", "CNOT3", "COLEC12", "CPD", "CPVL", "CSRP2", "CTH", "CTSA", "CYFIP1", "CYP51A1", "DHCR24", "DHCR7", "DHX36", "DNAJC10", "DNM3", "DOCK1", "DOCK7", "ECE1", "EED", "EPHA7", "ERAP1", "EXO1", "FAM3C", "FECH", "FLII", "FNTA", "FOXRED1", "FUCA1", "FUCA2", "FXR1", "GAA", "GLA", "GLB1", "GLT8D1", "GNG12", "GPAM", "GSR", "GYS1", "HELLS", "HMOX2", "HOOK1", "IDH2", "IGF2R", "INA", "IQCB1", "IQGAP3", "KDM1B", "KDM2A", "KIAA1147", "KIF11", "KIF22", "KIF23", 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0000000000000000000000000000000000000000..3f8d002e03696e21fa5918ad585bf49016583cdd --- /dev/null +++ b/protein_atlas_protein_class/consensus.joblib @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1da9e2936419b20223757f75c702341cf988b5d6ba622bcba1a663341351ddc9 +size 102380 diff --git a/protein_atlas_protein_class/df_merge.tsv b/protein_atlas_protein_class/df_merge.tsv new file mode 100644 index 0000000000000000000000000000000000000000..6cfcc2bb919085c14cdb2d6ca589ad25f1b01f62 --- /dev/null +++ b/protein_atlas_protein_class/df_merge.tsv @@ -0,0 +1,5 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Predicted membrane proteins 203 706 5.357223586237925 8.451051537578027e-08 204.61650485436897 563.8058252427185 3.080866334016093 0.3028099075873978 81.17076282318972 73.52280648113661 4.068861305085399 0.4187410497068249 0.1669001598507077 3.992971285407914e-06 1.8050524301710747e-06 6.218475667588133e-10 4.484840354621092e-16 +Predicted secreted proteins 19 64 3.256048239647522 0.0011297455528587 15.29368932038835 51.737864077669904 1.393291060716792 0.256881456821794 5.463351773637434 6.9884942404294375 1.5049506819867255 0.3173597508227758 1.0 0.0015436632014479 4.68422461524682e-05 0.0008046975933989 0.0060773586951327 +Disease related genes 205 1147 2.296085814416671 0.0216709752277544 188.59708737864077 1017.8567961165048 0.1605786021463577 0.548804652764235 48.10710937168394 99.21246387321192 1.121307604609006 0.3723919943404348 0.3719307469115097 0.2494267458572102 0.293607658873303 0.0490876252424668 2.352880383694784e-05 +FDA approved drug targets 28 136 2.0577182254610342 0.039617189807475 24.04854368932039 119.4247572815534 0.6623112070438231 0.5745671660823485 8.39802177443113 10.190737689187452 0.8635117376862006 0.3683507047501689 0.2817240684487549 0.0027670616369496 0.0005769894192108 0.006471971429424 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mode 100644 index 0000000000000000000000000000000000000000..8b0ffd3e8f86c07d55385e97f602e5c82cd7d83f --- /dev/null +++ b/protein_atlas_protein_class/result.tsv @@ -0,0 +1,9 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Predicted membrane proteins 0.434319743852517 5.357223586237925 8.451051537578027e-08 1.6902089505511237e-06 8.451051537678026e-07 706 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203 +Predicted secreted proteins 0.5708819054869962 3.256048239647522 0.0011297455528587 0.0223540452320563 0.0075316370190581 64 P07942,Q08380,P14174,Q9UM22,Q9UMX5,P05067,Q9HB40,P22466,O75718,Q8WUJ1,Q8NDZ4,Q02818,P43490,Q9H9S5,P80303,O00584,Q9NZ08,Q15165,Q9BTY2 19 +Disease related genes 0.2846947326382968 2.296085814416671 0.0216709752277544 0.3547934543077864 0.0866839009110176 1147 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205 +FDA approved drug targets 0.3844726974973508 2.0577182254610342 0.039617189807475 0.5544591171140032 0.1320572993582502 136 Q99720,P54619,P20618,Q7L0J3,P10253,P00390,P05067,P20645,P02786,P28074,P16615,P80404,O75116,P00813,P49721,P03886,Q16850,P12814,P55011,P23786,Q8N0U8,Q16739,Q13464,Q7LG56,P48735,P11274,P49354,Q13423 28 +Transporters 0.3941628997490648 1.562922610982591 0.1180707986067735 0.9189646609210004 0.236141597213547 437 Q99720,Q8WTV0,O96008,Q6NT16,Q8IXU6,O43772,Q15629,Q99442,O75027,Q5VW38,Q9HC21,P05067,Q16625,Q9NR77,O60313,P20645,P53985,Q9BQT8,Q8TB61,Q96GC9,Q96L92,Q9BXS4,Q8NHS3,P30825,O43865,P24390,O00410,P00403,P20674,Q16891,P07602,P45880,Q93050,P41440,Q9BRK5,Q13555,O15260,Q99523,O43681,Q9NUN5,Q01650,Q9H813,Q8TCT8,P11717,O95563,Q8N4V1,Q9UH99,P16615,Q07065,Q9C0E2,O14678,Q9HD20,Q9Y6K0,O15127,P55735,P78536,Q567U6,O60637,Q6UW68,Q9H4I9,P57105,O75955,Q9NWW5,O60826,O75844,Q8IYU8,Q9BSK2,Q86VD7,Q14108,O15118,Q96H78,P39210,Q12834,P11166,Q70HW3,Q9UBX3,Q9NWR8,O75787,Q6P4Q7,Q9BPX6,P33176,Q16739,Q8N1F7,P04843,Q9Y6M7,Q96N66,P61916,Q8TBA6,Q9HC07,Q99805,P02786,Q15070,Q6ZXV5,Q9BUB7,P55011,Q9BTX1,Q8IY95,O43752,O14523,P51798,Q9H300 101 +Human disease related genes 0.2676016800482361 1.369843838256935 0.1707356542132825 0.9763484359216348 0.3104284622059682 1028 P22830,Q99720,Q86XL3,Q01105,P27544,P07099,Q7RTS9,O43772,P14174,O75419,Q9H1P3,Q8N201,O75027,Q9BRT2,O75503,Q9HC21,P05067,Q16625,P13807,Q9NR77,A2RRP1,O60313,O60566,P10321,P22466,Q9Y487,P53985,Q15392,O95831,Q8NHS3,P42892,P00813,P10619,P03886,P07602,Q8IV08,P50897,P00846,Q9Y4G8,O75530,O96028,Q96CU9,O00584,P08670,Q13555,Q15437,P15291,Q16740,O75380,Q9NUN5,P07196,Q9GZY8,P07942,P55263,P98175,Q4J6C6,Q71SY5,P54802,P06280,P16278,Q9UHX1,O43676,P16615,O14678,P32929,Q13049,Q6DKK2,Q9Y3D3,O15078,P23786,O43505,Q03252,O15484,P09493,P78536,Q15051,P04066,Q9NX62,P25705,P11117,Q9NWW5,O60826,O75844,Q14108,O15344,O15118,Q9HD42,Q8TD16,P02545,P10253,P39210,Q9Y5Z9,Q9Y366,Q9UBM7,Q7KZN9,P35579,P11166,Q70HW3,Q9UBX3,Q9BY67,Q96L58,Q96JJ3,Q7Z406,O75787,O75718,O75251,Q6P4Q7,Q9Y6M1,Q9BPX6,Q96RR1,Q969N2,Q92542,Q13813,P50336,P22695,P20700,P20585,P12814,P52732,O43707,Q96F07,Q9H9S5,Q8N1F7,P48735,Q96N66,Q15555,Q13423,P61916,O75569,P31751,Q96HY6,Q9NQH7,O00116,Q9HC07,Q8WVM7,Q96N67,P06753,O75298,O14773,Q96EK5,Q8NCH0,Q8WVQ1,P49748,Q8N0X7,P80404,P15586,Q14203,Q14739,Q6ZXV5,Q9BUB7,O14936,O00754,Q15056,Q8WXW3,Q7LG56,P30533,P11177,P08236,P51798,Q9BX67,Q9NWS8,Q9UQE7,P35606,P46783,O75306,Q14331,Q86YV9,Q8NAT1,Q96RK4,Q9NUQ7,Q9UEY8,Q9UIG0 172 +CD markers 0.3803354929212588 0.6856157159908294 0.4929554684280044 0.9999987383988824 0.7042220977542921 21 P11717,Q13740,O75330,P02786,P17301,P06756,P35613,Q9NPF0,P78536,P19022,P08195 11 +Candidate cardiovascular disease genes 0.3643368161894142 0.3541892445315427 0.7231970634493865 0.9999999999930272 0.8508200746463371 12 Q15165 1 diff --git a/protein_atlas_protein_class/selections.json b/protein_atlas_protein_class/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..00036c553f75e044ec1e25fd45488b66e5655332 --- /dev/null +++ b/protein_atlas_protein_class/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Blood group antigen proteins", "CD markers", "Cancer-related genes", "Candidate cardiovascular disease genes", "Citric acid cycle related proteins", "Disease related genes", "Enzymes", "FDA approved drug targets", "Human disease related genes", "Metabolic proteins", "Plasma proteins", "Potential drug targets", "Predicted intracellular proteins", "Predicted membrane proteins", "Predicted secreted proteins", "RAS pathway related proteins", "RNA polymerase related proteins", "Ribosomal proteins", "Transcription factors", "Transporters"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASDHPPT", "AASS", "AATF", "ABAT", "ABCB1", "ABCB10", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCD4", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD12", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACACB", "ACAD10", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACP2", "ACP6", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR3", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADH5", "ADI1", "ADK", "ADNP", "ADO", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGAP3", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH16A1", "ALDH18A1", "ALDH1A2", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKHD1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1M1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP2S1", "AP3B1", "AP3D1", "AP3M1", "AP3S1", "AP4M1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOC1", "APOL2", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF4", "ARF5", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARHGEF2", "ARHGEF7", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL10", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL6IP6", "ARL8B", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC2", "ARPC3", "ARPC4", "ARRB2", "ARV1", "ARVCF", "AS3MT", "ASAH1", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1A1", "ATP1B1", "ATP1B3", "ATP2A2", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5C1", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6", "ATP6AP1", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "ATP6V0D1", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B3GALT6", "B3GAT3", 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"CAPNS1", "CAPRIN1", "CAPZA1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC127", "CCDC134", "CCDC137", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCDC94", "CCDC97", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC123", "CDC20", "CDC23", "CDC27", "CDC37", "CDC42", "CDC42BPB", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKAL1", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPH", "CENPK", "CENPP", "CENPU", "CENPV", "CEP131", "CEP170", "CEP250", "CEP290", "CEP44", "CEPT1", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHERP", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP3", "CHMP4B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP4", "CKAP5", "CKB", "CKMT1A*", "CLASP1", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLCN7", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN5", "CLN6", "CLNS1A", "CLPB", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLSTN3", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT4", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COASY", "COG3", "COG5", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD2", "COMMD6", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPG2", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COPZ1", "COQ3", "COQ8A", "CORO1B", "CORO1C", "CORO7", "COTL1", "COX1", "COX14", "COX15", "COX18", "COX2", "COX4I1", "COX5A", "COX5B", "COX6C", "COX7A2L", "COX7C", "CPD", "CPNE1", "CPNE3", "CPNE8", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF3", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CRNKL1", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSNK2A2", "CSNK2B", "CSRP2", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTH", "CTNNA1", "CTNNAL1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR24", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIEXF", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOCK7", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPM1", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSE", "DSG2", "DSP", "DST", "DSTN", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECE1", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF2S3", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3F", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOB", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC1", "EMC2", "EMC3", "EMC4", "EMC7", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENDOG", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA7", "EPHX1", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERGIC3", "ERH", "ERICH1", "ERLIN1", "ERLIN2", "ERMP1", "ERO1A", "ERO1B", "ERP29", "ERP44", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETF1", "ETFA", "ETFB", "ETFDH", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC5", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC6", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FADS2", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM160B2", "FAM162A", "FAM173A", "FAM177A1", "FAM207A", "FAM208A", "FAM208B", "FAM213A", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FECH", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIGNL1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP1A", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FN3KRP", "FNBP1", "FNBP4", "FNDC3A", "FNTA", "FOXRED1", "FRG1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUCA2", "FUNDC1", "FUNDC2", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNS", "GALNT1", "GALNT2", "GALNT4", "GALNT7", "GAMT", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBA", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP2", "GDE1", "GDI1", "GDI2", "GDPD1", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGCT", "GGCX", "GGH", "GGPS1", "GHDC", "GHITM", "GID4", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLA", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX3", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLYR1", "GM2A", "GMDS", "GMFB", "GMPPA", "GMPPB", "GMPS", "GNA11", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNAO1", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPAT", "GNPDA1", "GNS", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR1", "GOSR2", "GOT1", "GOT2", "GPAA1", "GPAM", "GPAT4", "GPATCH11", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTA4", "GSTK1", "GSTM2", "GSTM3", "GSTO1", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP10", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD2", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS4", "HAUS5", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HEBP2", "HECTD1", "HECTD3", "HELLS", "HERC2", "HEXA", "HEXB", "HEXIM1", "HGH1", "HGS", "HIBADH", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1D", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLA-B", "HLA-C", "HLA-F", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCL", "HMGCR", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK1", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HPS6", "HS1BP3", "HS2ST1", "HSD17B10", "HSD17B11", "HSD17B12", "HSD17B4", "HSD17B7", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA13", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPE1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "HYOU1", "IAH1", "IARS", "IARS2", "IBA57", "ICMT", "IDE", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IDI1", "IFIT5", "IFT27", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS2", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRGQ", "IRS4", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITM2C", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KDSR", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFBP", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KNOP1", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMB1", "LAMC1", "LAMP1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDAH", "LDHA", "LDHB", "LDLR", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGALS3BP", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLGL1", "LLPH", "LMAN1", "LMAN2", "LMAN2L", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LONP1", "LONP2", "LPCAT1", "LPGAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC45", "LRRC47", "LRRC57", "LRRC59", "LRRC8A", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM5", "LSM6", "LSM7", "LSM8", "LSS", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYRM2", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "M6PR", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED2", "MAGT1", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP4", "MAP7D1", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARC2", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MARS2", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCFD2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED24", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD3", "MFSD5", "MFSD8", "MGAT1", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MLEC", "MMAB", "MMGT1", "MMS19", "MOB4", "MOCOS", "MOCS1", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPC2", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP6", "MPP7", "MPRIP", "MPST", "MPV17", "MPV17L2", "MRE11", "MRFAP1", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL13", "MRPL14", "MRPL15", "MRPL16", "MRPL17", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL24", "MRPL28", "MRPL3", "MRPL37", "MRPL38", "MRPL39", "MRPL4", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL49", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS17", "MRPS18A", "MRPS2", "MRPS22", "MRPS23", "MRPS24", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS30", "MRPS31", "MRPS33", "MRPS34", "MRPS35", "MRPS5", "MRPS6", "MRPS7", "MRPS9", "MRRF", "MRS2", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH1", "MTCH2", "MTDH", "MTERF3", "MTF2", "MTFP1", "MTFR1", "MTG1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYDGF", "MYG1", "MYH10", "MYH14", "MYH9", "MYL6", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAGLU", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG", "NCAPG2", "NCAPH", "NCBP1", "NCBP2AS2", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "ND1", "ND5", "NDC1", "NDE1", "NDRG3", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA2", "NDUFA3", "NDUFA4", "NDUFA5", "NDUFA6", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF3", "NDUFAF4", "NDUFAF7", "NDUFB1", "NDUFB10", "NDUFB11", "NDUFB3", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS6", "NDUFS7", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK3", "NEK9", "NELFA", "NELFCD", "NELFE", "NEMF", "NENF", "NES", "NFATC2IP", "NFKBIL1", "NFS1", "NFU1", "NHLRC2", "NHP2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP1", "NIPSNAP2", "NIPSNAP3A", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPC2", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRM", "NRP1", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSMCE3", "NSUN2", "NSUN4", "NSUN5", "NT5C2", "NT5C3A", "NT5C3B", "NT5DC1", "NT5DC2", "NTHL1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT12", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP160", "NUP188", "NUP205", "NUP210", "NUP214", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP58", "NUP62", "NUP85", "NUP88", "NUP93", "NUP98", "NUPL2", "NUTF2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAWR", "PAX6", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCCB", "PCDH7", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE12", "PDE4DIP", "PDE6D", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK1", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDXP", "PDZD11", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PET100", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN4", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGAM1", "PGAM5", "PGD", "PGK1", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGG", "PIGK", "PIGL", "PIGS", "PIGT", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITHD1", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLBD2", "PLCG1", "PLD3", "PLD6", "PLEC", "PLIN3", "PLK1", "PLOD1", "PLOD2", "PLOD3", "PLPBP", "PLRG1", "PLS1", "PLS3", "PLXNB2", "PMF1", "PMPCA", "PMPCB", "PMS1", "PMVK", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POFUT2", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POMGNT2", "PON2", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAN", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1CC", "PPP1R10", "PPP1R12A", "PPP1R14B", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX2", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREP", "PREPL", "PRIM1", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKAR2A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT3", "PRMT5", "PROCR", "PRPF19", "PRPF3", "PRPF31", "PRPF38B", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA2", "PSMA3", "PSMA4", "PSMA5", "PSMA6", "PSMA7", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD2", "PSMD3", "PSMD4", "PSMD6", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSMG3", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTDSS2", "PTGES2", "PTGES3", "PTGR1", "PTGR2", "PTK7", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PURA", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PXMP2", "PXMP4", "PYCR1", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "R3HCC1", "RAB10", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB18", "RAB1A", "RAB1B", "RAB21", "RAB23", "RAB24", "RAB2A", "RAB31", "RAB35", "RAB39A", "RAB3GAP1", "RAB3GAP2", "RAB4A", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTA", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAP2B", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCC2", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH11", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP3", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RFX1", "RHBDD2", "RHEB", "RHOG", "RHOT1", "RHOT2", "RIC8A", "RIDA", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN2", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2C", "RNASET2", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK1", "ROCK2", "RPA1", "RPA2", "RPA3", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL15", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL36", "RPL36A", "RPL37", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS15A", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPS9", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN2", "RTN3", "RTN4", "RTN4IP1", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCFD1", "SCLY", "SCML2", "SCO1", "SCO2", "SCOC", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SDAD1", "SDCBP", "SDCCAG3", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC22B", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC61G", "SEC62", "SEC63", "SEH1L", "SEL1L", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIGMAR1", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLAIN2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A1", "SLC25A10", "SLC25A11", "SLC25A12", "SLC25A13", "SLC25A15", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A21", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A33", "SLC25A4", "SLC25A40", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC29A1", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A1", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLIT2", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG1", "SMG8", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD1", "SNRPD2", "SNRPD3", "SNRPE", "SNU13", "SNW1", "SNX1", "SNX12", "SNX17", "SNX2", "SNX27", "SNX3", "SNX4", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPCS3", "SPDL1", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SPTLC2", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRP72", "SRP9", "SRPK1", "SRPRA", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSNA1", "SSR1", "SSR3", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRBP", "STRIP1", "STRN", "STT3A", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "SYS1", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TAPBP", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D10B", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBCD", "TBCE", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCF25", "TCOF1", "TCP1", "TCP11L1", "TCTN3", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFB1M", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THADA", "THAP11", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM10B", "TIMM13", "TIMM17A", "TIMM17B", "TIMM22", "TIMM23", "TIMM44", "TIMM50", "TIMM8B", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TK1", "TKFC", "TKT", "TLCD1", "TLE3", "TLN1", "TM7SF2", "TM9SF2", "TM9SF3", "TM9SF4", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMED5", "TMED7", "TMED9", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM131", "TMEM14C", "TMEM160", "TMEM161A", "TMEM165", "TMEM167A", "TMEM192", "TMEM199", "TMEM201", "TMEM205", "TMEM206", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM30A", "TMEM33", "TMEM35B", "TMEM38B", "TMEM43", "TMEM59", "TMEM65", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMOD1", "TMOD3", "TMTC3", "TMX1", "TMX2", "TMX3", "TMX4", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP1", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAM1", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM13", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC26", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TTYH3", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBG1", "TUBGCP2", "TUBGCP3", "TUFM", "TWF1", "TWF2", "TWISTNB", "TWNK", "TXLNA", "TXLNG", "TXNDC12", "TXNDC15", "TXNDC17", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYMS", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2G2", "UBE2J1", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBE4B", "UBFD1", "UBIAD1", "UBL5", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGCG", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC119", "UNC119B", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCR10", "UQCRB", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP19", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXS1", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VAT1", "VBP1", "VCL", "VCP", "VDAC1", "VDAC2", "VDAC3", "VEZT", "VIM", "VIPAS39", "VIRMA", "VKORC1L1", "VMA21", "VMP1", "VPS13A", "VPS13D", "VPS16", "VPS18", "VPS25", "VPS26A", "VPS28", "VPS29", "VPS33A", "VPS33B", "VPS35", "VPS36", "VPS37B", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "VWA8", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR43", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR73", "WDR74", "WDR75", "WDR77", "WDR82", "WDR89", "WDR91", "WFS1", "WIZ", "WLS", "WNK1", "WRAP73", "WRN", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPO7", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF2", "YTHDF3", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZCRB1", "ZDHHC13", "ZFPL1", "ZFR", "ZFYVE16", "ZMAT2", "ZMPSTE24", "ZMYM1", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZNF687", "ZNHIT2", "ZPR1", "ZW10", "ZWILCH", "ZYX"], "leading_proteins": ["ABAT", "ABCB7", "ABCD4", "ACADVL", "ACP2", "ACSL6", "ACTN1", "ACTN4", "ADA", "ADAM17", "ADD3", "ADK", "AGPS", "AHCYL1", "AIFM1", "AKT2", "ALCAM", "ANKLE2", "APLP2", "APP", "ARHGAP1", "ARHGEF1", "ARIH1", "ARL10", "ARMC10", "ASNA1", "ATP13A1", "ATP2A2", "ATP5A1", "ATP5L", "ATP6", "ATP6AP2", "ATP6V0A1", "ATP6V0A2", "B3GALT6", "B4GALT1", "B4GAT1", "BAZ1B", "BBS4", "BCL2L13", "BCR", "BICD2", "BRD3", "BSG", "BUB1B", "C2CD2L", "C3orf58", "CADM1", "CAMK1", "CAMK2G", "CANT1", "CAPN5", "CASK", "CCDC22", "CCDC93", "CD320", "CDC20", "CDC45", "CDH2", "CENPK", "CEP290", "CEPT1", "CERS1", "CERS2", "CHMP1A", "CHST14", "CIP2A", "CISD1", "CKAP4", "CLCN3", "CLCN7", "CLN5", "CLN6", "CLPP", "CLPTM1L", "CLSTN3", "CNNM4", "COA3", "COLEC12", "COPB2", "COX15", "COX2", "COX5A", "CPD", "CPT2", "CRTAP", "CTH", "CTSA", "CYB5B", "CYB5D2", "CYFIP2", "CYP51A1", "DCP1B", "DCTN1", "DDRGK1", "DHCR24", "DHCR7", "DHX36", "DNAJC1", "DNAJC10", "DOCK7", "DYM", "ECE1", "EED", "EFCAB14", "EIF4H", "ELMO2", "EPDR1", "EPHA7", "EPHX1", "ERAP1", "ERGIC3", "EXOSC2", "FAM162A", "FECH", "FGFR1OP", "FKRP", "FLAD1", "FLOT1", "FNBP1", "FNTA", "FOXRED1", "FRG1", "FUCA1", "FUCA2", "FXR1", "GAA", "GAL", "GALNT1", "GLA", "GLB1", "GLG1", "GLT8D1", "GNS", "GOLGA5", "GOLIM4", "GPAM", "GPR107", "GPR108", "GSR", "GUSB", "GYS1", "HIP1", "HLA-C", "HLA-F", "HMMR", "HMOX2", "HPS6", "IDH2", "IFT52", "IGF2BP2", "IGF2R", "IKBIP", "IMMT", "IMPAD1", "INPP4A", "INTS1", "IPO5", "IQCB1", "ITGA2", "ITGAV", "ITM2C", "JAM3", "KDELR1", "KIAA0319L", "KIAA2013", "KIF11", "KIF5B", "KIFBP", "KNSTRN", "KTN1", "LAMB1", "LAPTM4A", "LBR", "LGALS3BP", "LMBRD1", "LMNA", "LMNB1", "LMNB2", "LNPEP", "LRPAP1", "M6PR", "MAD1L1", "MAN1A2", "MAN2B1", "MANEA", "MAPRE2", "MAVS", "MBOAT7", "MCL1", "MCUB", "MED25", "MFF", "MFSD8", "MICU1", "MICU2", "MID1", "MIF", "MMGT1", "MPC2", "MPG", "MPV17", "MPV17L2", "MRPS16", "MSH3", "MSI2", "MSN", "MTAP", "MTX1", "MYH10", "MYH14", "MYH9", "NAGLU", "NAMPT", "NBAS", "NCEH1", "NCSTN", "ND1", "NDC1", "NDUFB3", "NDUFS2", "NDUFS6", "NDUFS7", "NEFL", "NENF", "NNT", "NPC1", "NPC2", "NRDE2", "NSD2", "NUCB1", "NUCB2", "NUP93", "OCLN", "ODR4", "OPA1", "OPA3", "OSBPL2", "OXA1L", "PARL", "PDE4DIP", "PDHB", "PGRMC2", "PIBF1", "PIGG", "PIGT", "PLA2G15", "PLD3", "PLD6", "POMGNT2", "PON2", "PPFIA1", "PPIL3", "PPOX", "PPT1", "PREPL", "PRKAG1", "PRKRA", "PSAP", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PTPMT1", "PTPRF", "PUF60", "PXMP2", "RAPGEF2", "RBM10", "RMND1", "RNASET2", "ROCK1", 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index 0000000000000000000000000000000000000000..ddd2c83070fd5d3d3bbd6ce2a64fd204cbeb5e79 --- /dev/null +++ b/protein_atlas_subcellular_location_all/df_merge.tsv @@ -0,0 +1,2 @@ +term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500 +Golgi apparatus 61 235 2.4718043766885907 0.0134433056692797 46.45873786407767 176.03155339805826 1.3643789213018729 0.3972771337532677 14.511319530749702 26.453870355965975 1.6568954592349954 0.4161874156663988 0.5201111350704553 0.0109440159670694 0.000138385341709 4.6929308840705225e-05 1.390691756850523e-06 diff --git a/protein_atlas_subcellular_location_all/metrics.json b/protein_atlas_subcellular_location_all/metrics.json new file mode 100644 index 0000000000000000000000000000000000000000..7ca891175cd2e7aaa4983ff8b5de697fe6c42607 --- /dev/null +++ b/protein_atlas_subcellular_location_all/metrics.json @@ -0,0 +1,7 @@ +{ + "type_of_task": "ranksum", + "signature_size": 3643, + "annotations_size": 33, + "title": "Average number of proteins per term", + "value": 167.78787878787878 +} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/paths.json b/protein_atlas_subcellular_location_all/paths.json new file mode 100644 index 0000000000000000000000000000000000000000..ca4befd2daf0d43d2ec55866d771c7e2058089f9 --- /dev/null +++ b/protein_atlas_subcellular_location_all/paths.json @@ -0,0 +1 @@ +{"results_path": "results/proteins/hek293t_core/protein_atlas_subcellular_location_all/fragment/C024/C024_val_log2fc"} \ No newline at end of file diff --git a/protein_atlas_subcellular_location_all/result.tsv b/protein_atlas_subcellular_location_all/result.tsv new file mode 100644 index 0000000000000000000000000000000000000000..5482199cb18f1eb739c18cca1f23048d1248d7d2 --- /dev/null +++ b/protein_atlas_subcellular_location_all/result.tsv @@ -0,0 +1,12 @@ +Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size +Golgi apparatus 0.4330759739689326 2.4718043766885907 0.0134433056692797 0.3602245379656846 0.221814543543116 235 O15344,Q92896,Q9HC07,Q6NT16,Q7RTS9,Q8IXU6,Q8IZA0,O43493,Q8TD16,Q9HD45,Q86SX3,O60476,Q5KU26,O14976,Q5VW38,P05067,Q8IYS2,P16278,P11717,O00231,Q9HB40,Q8NCH0,Q8WVQ1,P22466,Q08379,O75071,Q9NPR9,Q02818,O60499,O15127,P50897,O00461,Q8NBJ4,Q8IWJ2,Q5VU43,Q93050,Q9H9S5,O43752,O60512,Q9H3P7,Q9BX67,P80303,Q969M3,Q8NBN3,Q9BRK5,O60637,Q6ZVM7,Q15012,Q5SRI9,Q9NX62,Q96CN9,P35606,O15260,Q99523,Q01082,P15291,O75955,P10586,O95456,Q8TBA6,A4D1U4 61 +Lysosomes 0.6196730604621998 1.7901210543658876 0.0734344527795305 0.919292689935215 0.5839412792024258 14 Q8WTV0,P02786,Q8IY95,O15400 4 +Intermediate filaments 0.4480198344077472 1.6310817926043817 0.1028730619852 0.972191432671011 0.5839412792024258 41 P07197,Q96K76,Q9Y496,P08670,Q15102,Q16352,O75718,Q6ZVM7,Q13049,P07196,Q92545 11 +Centriolar satellite 0.3765247534933931 0.9267123156046432 0.3540759214701441 0.999999455511574 1.0 35 Q13045,Q9Y5K6,O15344,O43169,O60271,Q03518,Q14498,Q5SVZ6,P33176,Q71F23,Q8WXW3,Q9Y4W2,Q9Y448,Q9P260,Q15154,P11413,Q15691,Q86VS8,Q9Y6A5,Q9UPN4 20 +Lipid droplets 0.4424595357090345 0.6887625725831321 0.4909726921623667 0.9999999997898856 1.0 10 Q01105,A3KMH1 2 +Actin filaments 0.3205420757011345 0.6661630403052036 0.5053068939761061 0.9999999999181378 1.0 50 P35579,P12814,P35580,Q9BTX1,O75718,O43707,Q6WCQ1,P06753,Q6P4Q7,Q9NUG6,P09493,P67936 12 +Focal adhesion sites 0.3226514727874103 0.4213246284059967 0.6735180484857963 1.0 1.0 31 P12814,O60888,Q9Y487,P49770,Q13136,Q969Q5,Q9Y6M7 7 +Mitotic chromosome 0.3022065026348318 0.3697274935483249 0.7115855442740833 1.0 1.0 40 Q9Y3B9,Q9H3R5,Q9BYG3,Q86VI3,Q5QJE6,Q8TBB5,O75683,Q9Y3T9,O76021,Q9NY93,Q13601,Q76FK4 12 +Vesicles 0.3267201710568499 0.3402534707722995 0.7336656538244584 1.0 1.0 362 P42785,Q8WUH2,O15118,Q8WTV0,P30519,Q01650,Q9HD45,Q96CN7,Q9P1Z2,P40938,P10253,Q9Y5Z9,Q8TCT8,Q8NCC3,P05067,Q8N8N7,P16278,P11717,P22466,Q06481,Q9NWR8,Q9Y487,Q07960,Q9NPR9,Q92564,Q96ED9,Q8NHS3,Q9HD20,O75592,P10619,Q13813,P50336,Q9NRY5,O60499,P07602,O15127,P50897,Q9NZM3,P55735,Q8NBX0,Q96RU3,Q9UMR5,Q93050,Q8IXH7,Q567U6,Q969M3,Q92545,Q9UFC0,P04066,Q15075,O75153,Q15437,Q8NCA5,Q5M775,A3KMH1,O75955,Q9NWW5,O60826,Q9NUN5 59 +Endosomes 0.3037196483264004 0.1271222271000892 0.8988436594971303 1.0 1.0 12 P02786,Q8IY95,Q00610,O60749 4 +Nuclear membrane 0.257528800441466 0.1172980304010218 0.9066238857700516 1.0 1.0 70 Q14728,Q96PE3,Q9Y6D9,Q96G23,A2RRP1,Q9UH99,O95168,P12270,P57740,A1A4S6,Q14739,Q5SNT2,P20700,Q9BTX1,Q9Y2U8,O75976,Q03252,Q9BZE4,P49792,P11802,P56134,P50402,Q6UW68,O15260,Q9NXW2 25 diff --git a/protein_atlas_subcellular_location_all/selections.json b/protein_atlas_subcellular_location_all/selections.json new file mode 100644 index 0000000000000000000000000000000000000000..ec852c8a766f3e8ccf18b0b8de6f698628d7a3ec --- /dev/null +++ b/protein_atlas_subcellular_location_all/selections.json @@ -0,0 +1 @@ +{"all_annotations": ["Actin filaments", "Cell Junctions", "Centriolar satellite", "Centrosome", "Cytokinetic bridge", "Cytoplasmic bodies", "Cytosol", "Endoplasmic reticulum", "Endosomes", "Focal adhesion sites", "Golgi apparatus", "Intermediate filaments", "Kinetochore", "Lipid droplets", "Lysosomes", "Microtubule ends", "Microtubules", "Midbody", "Midbody ring", "Mitochondria", "Mitotic chromosome", "Mitotic spindle", "Nuclear bodies", "Nuclear membrane", "Nuclear speckles", "Nucleoli", "Nucleoli fibrillar center", "Nucleoli rim", "Nucleoplasm", "Peroxisomes", "Plasma membrane", "Rods & Rings", "Vesicles"], "available_proteins": ["AAAS", "AAGAB", "AAK1", "AAMP", "AARS", "AARS2", "AARSD1", "AASS", "AATF", "ABAT", "ABCB1", "ABCB6", "ABCB7", "ABCB8", "ABCC1", "ABCC4", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABHD10", "ABHD11", "ABHD14B", "ABHD6", "ABI1", "ABR", "ABRAXAS2", "ABT1", "ACAA1", "ACAA2", "ACACA", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACO1", "ACO2", "ACOT1", "ACOT13", "ACOT7", "ACOT8", "ACOT9", "ACOX1", "ACOX3", "ACP1", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACTL6A", "ACTN1", "ACTN4", "ACTR10", "ACTR1A", "ACTR2", "ACTR6", "ACTR8", "ADA", "ADAM17", "ADAR", "ADD1", "ADD3", "ADI1", "ADK", "ADNP", "ADPGK", "ADRM1", "ADSL", "ADSS", "AFDN", "AFG3L2", "AGK", "AGL", "AGPAT1", "AGPAT5", "AGPS", "AHCTF1", "AHCY", "AHCYL1", "AHNAK", "AHSA1", "AIFM1", "AIMP1", "AIMP2", "AIP", "AK1", "AK2", "AK3", "AK4", "AKAP1", "AKAP12", "AKAP13", "AKAP17A", "AKAP8", "AKAP8L", "AKR1A1", "AKR1B1", "AKR7A2", "AKT1", "AKT1S1", "AKT2", "ALCAM", "ALDH18A1", "ALDH1B1", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ALG1", "ALG12", "ALKBH5", "AMFR", "AMOT", "AMPD2", "ANAPC1", "ANAPC16", "ANAPC2", "ANAPC4", "ANAPC5", "ANAPC7", "ANGEL1", "ANK3", "ANKFY1", "ANKLE2", "ANKRD17", "ANLN", "ANO6", "ANP32A", "ANP32B", "ANP32E", "ANXA1", "ANXA11", "ANXA2", "ANXA3", "ANXA6", "ANXA7", "AP1B1", "AP1G1", "AP1S1", "AP1S2", "AP2A1", "AP2A2", "AP2B1", "AP2M1", "AP3B1", "AP3D1", "AP3S1", "APBB1", "APEH", "APEX1", "API5", "APLP2", "APMAP", "APOBEC3C", "APOO", "APOOL", "APP", "APRT", "AQR", "ARCN1", "ARF6", "ARFGAP1", "ARFGAP2", "ARFIP1", "ARFIP2", "ARG2", "ARHGAP1", "ARHGAP10", "ARHGAP17", "ARHGAP5", "ARHGDIA", "ARHGEF1", "ARID1A", "ARID2", "ARID3B", "ARIH1", "ARIH2", "ARL1", "ARL2", "ARL3", "ARL6", "ARL6IP1", "ARL6IP4", "ARL6IP5", "ARL6IP6", "ARMC10", "ARMC6", "ARMCX3", "ARMT1", "ARPC2", "ARPC3", "ARRB2", "ARV1", "ARVCF", "AS3MT", "ASCC1", "ASCC2", "ASCC3", "ASNA1", "ASNS", "ASPH", "ASPSCR1", "ATAD1", "ATAD2", "ATAD3A", "ATAD3B", "ATAD5", "ATF7", "ATG3", "ATG4B", "ATG5", "ATG7", "ATIC", "ATL2", "ATL3", "ATP13A1", "ATP1B3", "ATP2B1", "ATP2B4", "ATP2C1", "ATP5A1", "ATP5B", "ATP5F1", "ATP5H", "ATP5I", "ATP5J", "ATP5J2", "ATP5L", "ATP5O", "ATP6V0A1", "ATP6V0A2", "ATP6V1A", "ATP6V1B2", "ATP6V1C1", "ATP6V1D", "ATP6V1E1", "ATP6V1H", "ATPAF1", "ATPAF2", "ATPIF1", "ATRX", "ATXN10", "ATXN2L", "AUP1", "AURKA", "AURKB", "B4GALT1", "B4GALT3", "BABAM2", "BAG2", "BAG3", "BAG5", "BAG6", "BAIAP2", "BANF1", "BAP18", "BASP1", "BAZ1B", "BAZ2A", "BBS4", "BCAP31", "BCAS2", "BCAS3", "BCAT2", "BCCIP", "BCKDK", "BCL2L12", "BCL2L13", "BCLAF1", "BCR", "BECN1", "BEND3", "BICD2", "BIRC6", "BLM", "BLMH", "BLVRA", "BMS1", "BNIP1", "BOLA2*", "BOP1", "BPNT1", "BPTF", "BRAT1", "BRCA1", "BRD2", "BRD3", "BRD4", "BRI3BP", "BRIP1", "BRIX1", "BROX", "BSDC1", "BSG", "BTF3", "BUB1B", "BUB3", "BUD23", "BUD31", "BYSL", "BZW1", "BZW2", "C10orf76", "C12orf43", "C12orf57", "C12orf73", "C14orf2", "C16orf58", "C17orf75", "C19orf25", "C19orf70", "C1QBP", "C1orf123", "C1orf198", "C1orf35", "C2CD2", "C2CD2L", "C2CD5", "C2orf49", "C5orf24", "C5orf51", "C8orf33", "C9orf64", "CAB39", "CABIN1", "CACYBP", "CAD", "CADM1", "CALCOCO1", "CALCOCO2", "CALD1", "CALR", "CALU", "CAMK1", "CAMK2G", "CAMSAP3", "CAND1", "CAND2", "CANT1", "CANX", "CAP1", "CAPN1", "CAPN2", "CAPN5", "CAPNS1", "CAPRIN1", "CAPZA2", "CAPZB", "CARM1", "CARS", "CASK", "CAST", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CC2D1A", "CCAR1", "CCAR2", "CCDC12", "CCDC124", "CCDC127", "CCDC137", "CCDC138", "CCDC22", "CCDC43", "CCDC47", "CCDC51", "CCDC58", "CCDC6", "CCDC86", "CCDC93", "CCDC94", "CCDC97", "CCT2", "CCT3", "CCT4", "CCT6A", "CCT7", "CCT8", "CD109", "CD2AP", "CD2BP2", "CD320", "CD47", "CDC123", "CDC20", "CDC27", "CDC37", "CDC42", "CDC45", "CDC5L", "CDC7", "CDC73", "CDCA8", "CDH2", "CDIPT", "CDK1", "CDK11B", "CDK16", "CDK2", "CDK4", "CDK5", "CDK5RAP1", "CDK5RAP2", "CDK5RAP3", "CDK6", "CDK9", "CDKN2AIP", "CDS2", "CDV3", "CEBPZ", "CELF1", "CELF2", "CENPB", "CENPE", "CENPH", "CENPP", "CENPU", "CENPV", "CEP131", "CEP170", "CEP250", "CEP290", "CERS1", "CERS2", "CETN2", "CFAP20", "CFDP1", "CFL1", "CFL2", "CHAF1A", "CHAF1B", "CHAMP1", "CHCHD3", "CHD1", "CHD1L", "CHD4", "CHD7", "CHD8", "CHEK2", "CHID1", "CHKA", "CHMP1A", "CHMP2A", "CHMP2B", "CHMP5", "CHMP7", "CHORDC1", "CHPF2", "CHST14", "CHTF18", "CHTOP", "CHUK", "CIAPIN1", "CIP2A", "CIRBP", "CISD1", "CISD2", "CIZ1", "CKAP2", "CKAP5", "CKB", "CLASP2", "CLCC1", "CLCN3", "CLCN6", "CLGN", "CLIC1", "CLIC4", "CLINT1", "CLN6", "CLNS1A", "CLPP", "CLPTM1", "CLPTM1L", "CLPX", "CLTA", "CLTB", "CLTC", "CLU", "CLUH", "CMAS", "CMPK1", "CMSS1", "CMTR1", "CNDP2", "CNN3", "CNNM3", "CNNM4", "CNOT1", "CNOT11", "CNOT3", "CNOT7", "CNOT9", "CNP", "CNPY2", "COA3", "COA7", "COG3", "COG5", "COG6", "COG7", "COG8", "COIL", "COLEC12", "COLGALT1", "COMMD8", "COMT", "COMTD1", "COPA", "COPB1", "COPB2", "COPE", "COPG1", "COPS2", "COPS3", "COPS4", "COPS5", "COPS6", "COPS7A", "COPS7B", "COPS8", "COQ3", "COQ8A", "CORO1B", "COTL1", "COX1", "COX14", "COX15", "COX4I1", "COX5B", "COX6C", "COX7A2L", "CPD", "CPNE1", "CPNE3", "CPOX", "CPPED1", "CPSF1", "CPSF2", "CPSF6", "CPSF7", "CPT1A", "CPT2", "CPVL", "CRK", "CRKL", "CROT", "CRTAP", "CRYZ", "CS", "CSDE1", "CSE1L", "CSK", "CSNK1A1", "CSNK2A1", "CSTB", "CSTF1", "CSTF2", "CSTF3", "CTBP1", "CTBP2", "CTDSPL2", "CTNNA1", "CTNNB1", "CTNNBL1", "CTNND1", "CTPS1", "CTPS2", "CTR9", "CTSA", "CTSC", "CTTN", "CTU2", "CUL1", "CUL2", "CUL4B", "CUL5", "CUTA", "CWC15", "CWC22", "CWC27", "CWF19L1", "CXADR", "CXorf57", "CYB5B", "CYB5D2", "CYB5R3", "CYC1", "CYFIP2", "CYP20A1", "CYP51A1", "DAD1", "DAGLB", "DAP3", "DARS", "DARS2", "DAXX", "DAZAP1", "DBN1", "DBNL", "DBT", "DCAF1", "DCAF13", "DCAF7", "DCAF8", "DCAKD", "DCK", "DCP1A", "DCP1B", "DCPS", "DCTN1", "DCTN2", "DCTN3", "DCTN4", "DCTPP1", "DCUN1D1", "DCUN1D3", "DCUN1D4", "DCUN1D5", "DCXR", "DDA1", "DDB1", "DDI2", "DDOST", "DDRGK1", "DDT", "DDX1", "DDX10", "DDX17", "DDX18", "DDX20", "DDX21", "DDX23", "DDX24", "DDX28", "DDX39A", "DDX39B", "DDX3X", "DDX41", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX50", "DDX51", "DDX52", "DDX54", "DDX56", "DDX6", "DEK", "DENND4C", "DENR", "DERL1", "DFFA", "DGCR8", "DHCR7", "DHFR", "DHPS", "DHRS1", "DHRS13", "DHRS4", "DHRS7", "DHRS7B", "DHTKD1", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX37", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIABLO", "DIAPH1", "DIAPH3", "DICER1", "DIDO1", "DIP2B", "DIS3", "DKC1", "DLAT", "DLD", "DLG3", "DLGAP5", "DLST", "DMAC2", "DMAP1", "DNAAF5", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB12", "DNAJB6", "DNAJC1", "DNAJC11", "DNAJC13", "DNAJC16", "DNAJC2", "DNAJC21", "DNAJC3", "DNAJC7", "DNAJC8", "DNAJC9", "DNM1L", "DNM2", "DNM3", "DNMT1", "DNPH1", "DNTTIP2", "DOCK1", "DOHH", "DOLPP1", "DPF2", "DPH1", "DPH2", "DPH5", "DPP3", "DPP9", "DPY30", "DPYSL2", "DPYSL5", "DRG1", "DRG2", "DSC3", "DSG2", "DSP", "DST", "DTYMK", "DUSP12", "DUSP3", "DUSP9", "DUT", "DVL2", "DYM", "DYNC1H1", "DYNC1I2", "DYNC1LI1", "DYNC1LI2", "DYNC2H1", "DYNLL1", "DYNLL2", "EARS2", "EBNA1BP2", "ECD", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "ECSIT", "EDC3", "EDC4", "EDF1", "EDRF1", "EEA1", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF1E1", "EEF1G", "EEF2", "EFCAB14", "EFHD1", "EFHD2", "EFL1", "EFTUD2", "EHBP1", "EHD1", "EHD4", "EI24", "EIF2A", "EIF2AK2", "EIF2B1", "EIF2B2", "EIF2B3", "EIF2B4", "EIF2B5", "EIF2D", "EIF2S1", "EIF2S2", "EIF3A", "EIF3B", "EIF3D", "EIF3E", "EIF3G", "EIF3H", "EIF3I", "EIF3J", "EIF3K", "EIF3L", "EIF3M", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4B", "EIF4E", "EIF4E2", "EIF4G1", "EIF4G2", "EIF4G3", "EIF4H", "EIF5", "EIF5A", "EIF5B", "EIF6", "ELAC2", "ELAVL1", "ELMO2", "ELMOD2", "ELOA", "ELOC", "ELP1", "ELP2", "ELP3", "ELP4", "EMC8", "EMD", "EMG1", "EML4", "ENAH", "ENDOD1", "ENO1", "ENO2", "ENY2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHX2", "EPN1", "EPPK1", "EPRS", "EPS15", "EPS15L1", "ERAL1", "ERAP1", "ERAP2", "ERBIN", "ERC1", "ERCC2", "ERCC3", "ERCC6L", "ERGIC1", "ERGIC2", "ERH", "ERICH1", "ERLIN1", "ERLIN2", "ERP29", "ESD", "ESF1", "ESS2", "ESYT1", "ESYT2", "ETFA", "ETFB", "ETNK1", "EWSR1", "EXD2", "EXO1", "EXOC1", "EXOC2", "EXOC3", "EXOC4", "EXOC6", "EXOC7", "EXOC8", "EXOSC1", "EXOSC10", "EXOSC2", "EXOSC3", "EXOSC4", "EXOSC5", "EXOSC7", "EXOSC8", "EXOSC9", "EXT2", "EZH2", "EZR", "F11R", "FAF1", "FAF2", "FAH", "FAHD1", "FAM114A2", "FAM120A", "FAM129B", "FAM160B2", "FAM162A", "FAM173A", "FAM177A1", "FAM207A", "FAM208A", "FAM208B", "FAM3C", "FAM49B", "FAM50A", "FAM8A1", "FAM91A1", "FAM98A", "FAM98B", "FANCG", "FANCI", "FAR1", "FAR2", "FARSA", "FARSB", "FASN", "FASTKD2", "FBL", "FDFT1", "FDPS", "FDXR", "FEM1A", "FEN1", "FERMT2", "FGFR1OP", "FH", "FHL1", "FHOD1", "FIP1L1", "FIS1", "FKBP10", "FKBP14", "FKBP15", "FKBP2", "FKBP3", "FKBP4", "FKBP5", "FKBP7", "FKBP8", "FKRP", "FLAD1", "FLII", "FLNA", "FLNB", "FLNC", "FLOT1", "FLOT2", "FMC1", "FMR1", "FN3KRP", "FNBP1", "FNBP4", "FNDC3A", "FNTA", "FOXRED1", "FRYL", "FSCN1", "FTO", "FTSJ3", "FUBP1", "FUBP3", "FUCA1", "FUS", "FXR1", "FXR2", "G3BP1", "G3BP2", "G6PD", "GAA", "GABARAPL2", "GABPA", "GADD45GIP1", "GAK", "GAL", "GALK1", "GALM", "GALNS", "GALNT2", "GALNT4", "GALNT7", "GANAB", "GAPDH", "GAPVD1", "GAR1", "GARS", "GART", "GATAD2A", "GATAD2B", "GATB", "GBF1", "GCAT", "GCC1", "GCC2", "GCDH", "GCFC2", "GCLC", "GCLM", "GCN1", "GDAP2", "GDE1", "GDI1", "GDI2", "GEMIN4", "GEMIN5", "GEMIN8", "GET4", "GFM1", "GFPT1", "GGA1", "GGPS1", "GHITM", "GID4", "GID8", "GIGYF2", "GINS2", "GINS3", "GINS4", "GIPC1", "GLB1", "GLDC", "GLG1", "GLMN", "GLO1", "GLOD4", "GLRX", "GLRX5", "GLS", "GLT8D1", "GLTP", "GLYR1", "GM2A", "GMFB", "GMPPA", "GMPS", "GNA13", "GNAI1", "GNAI2", "GNAI3", "GNG12", "GNL1", "GNL2", "GNL3", "GNL3L", "GNPDA1", "GOLGA2", "GOLGA3", "GOLGA5", "GOLGB1", "GOLIM4", "GOLM1", "GOLPH3", "GOLPH3L", "GOLT1B", "GOPC", "GORASP2", "GOSR2", "GOT1", "GPAA1", "GPAM", "GPATCH11", "GPATCH8", "GPD2", "GPHN", "GPI", "GPKOW", "GPN1", "GPR107", "GPR108", "GPR89B", "GPRASP2", "GPS1", "GPT2", "GPX8", "GRB2", "GRHPR", "GRPEL1", "GRSF1", "GRWD1", "GSK3A", "GSK3B", "GSPT1", "GSR", "GSS", "GSTK1", "GSTM2", "GSTM3", "GSTZ1", "GTF2B", "GTF2E1", "GTF2F1", "GTF2F2", "GTF2H1", "GTF2H4", "GTF2I", "GTF3C1", "GTF3C2", "GTF3C3", "GTF3C4", "GTF3C5", "GTPBP1", "GTPBP3", "GTPBP4", "GTPBP8", "GUF1", "GUSB", "GYG1", "GYS1", "H1F0", "H1FX", "H2AFX", "H2AFY", "H2AFY2", "H3-3A*", "H4C1*", "HACD3", "HACL1", "HADH", "HADHA", "HADHB", "HAT1", "HAUS1", "HAUS3", "HAUS6", "HAX1", "HBS1L", "HCCS", "HCFC1", "HDAC1", "HDAC2", "HDDC2", "HDGF", "HDGFL2", "HDGFL3", "HDHD2", "HDHD3", "HDHD5", "HDLBP", "HEATR1", "HEATR3", "HEATR6", "HEBP1", "HECTD1", "HELLS", "HERC2", "HEXA", "HEXIM1", "HGH1", "HGS", "HIBCH", "HIF1AN", "HIGD1A", "HIGD2A", "HINT2", "HINT3", "HIP1", "HIP1R", "HIST1H1C", "HIST1H1E", "HK1", "HK2", "HLA-A", "HLCS", "HLTF", "HM13", "HMBS", "HMCES", "HMG20A", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMGCS1", "HMGN1", "HMGN2", "HMMR", "HMOX1", "HMOX2", "HNRNPA0", "HNRNPA1", "HNRNPA2B1", "HNRNPA3", "HNRNPAB", "HNRNPC", "HNRNPD", "HNRNPDL", "HNRNPF", "HNRNPH1", "HNRNPH2", "HNRNPH3", "HNRNPK", "HNRNPL", "HNRNPM", "HNRNPR", "HNRNPU", "HNRNPUL1", "HNRNPUL2", "HOOK2", "HOOK3", "HP1BP3", "HPF1", "HPRT1", "HS1BP3", "HS2ST1", "HSD17B11", "HSD17B4", "HSDL1", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA12A", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPBP1", "HSPD1", "HSPH1", "HTATIP2", "HTATSF1", "HUWE1", "IAH1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "IFIT5", "IFT52", "IGBP1", "IGF2BP1", "IGF2BP2", "IGF2BP3", "IGF2R", "IGHMBP2", "IK", "IKBIP", "IKBKB", "ILF2", "ILF3", "ILK", "ILKAP", "ILVBL", "IMMT", "IMP3", "IMP4", "IMPACT", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "INCENP", "INF2", "INPP4A", "INTS1", "INTS11", "INTS14", "INTS3", "INTS4", "INTS5", "INTS9", "IPO11", "IPO4", "IPO5", "IPO7", "IPO8", "IPO9", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "IRF2BPL", "IRGQ", "ISOC1", "ISOC2", "IST1", "ISY1", "ISYNA1", "ITCH", "ITGA2", "ITGAV", "ITGB1", "ITPA", "ITPK1", "ITPRIP", "ITSN2", "IVD", "IWS1", "JAGN1", "JAM3", "JMJD6", "JPT2", "JUP", "KARS", "KAT7", "KATNA1", "KCTD12", "KCTD21", "KDELC2", "KDELR1", "KDM1A", "KDM1B", "KDM2A", "KDM3B", "KEAP1", "KHDRBS1", "KHSRP", "KIAA0319L", "KIAA0368", "KIAA0391", "KIAA1147", "KIAA1468", "KIAA2013", "KIDINS220", "KIF11", "KIF18B", "KIF20A", "KIF20B", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIFC1", "KIN", "KLC1", "KLC2", "KLHDC4", "KNOP1", "KNSTRN", "KNTC1", "KPNA1", "KPNA2", "KPNA3", "KPNA6", "KPNB1", "KRI1", "KRR1", "KTN1", "KYAT3", "L2HGDH", "LACTB", "LAMC1", "LAMP2", "LAMTOR1", "LAMTOR2", "LANCL1", "LANCL2", "LAP3", "LAPTM4A", "LARP1", "LARP4", "LARP4B", "LARP7", "LARS", "LARS2", "LAS1L", "LBR", "LCMT2", "LDHA", "LDHB", "LEMD2", "LEMD3", "LENG8", "LETM1", "LGALS3", "LGMN", "LIG1", "LIG3", "LIMA1", "LIN28B", "LIPA", "LLPH", "LMAN1", "LMBRD1", "LMF2", "LMNA", "LMNB1", "LMNB2", "LONP1", "LPCAT1", "LRBA", "LRCH2", "LRPAP1", "LRPPRC", "LRRC1", "LRRC40", "LRRC41", "LRRC45", "LRRC47", "LRRC57", "LRRC59", "LRRC8C", "LRSAM1", "LRWD1", "LSM12", "LSM14B", "LSM2", "LSM3", "LSM6", "LSM7", "LSM8", "LTA4H", "LTN1", "LTV1", "LUC7L2", "LUC7L3", "LYAR", "LYPLA1", "LYRM2", "LYSMD3", "LZIC", "LZTFL1", "LZTS2", "MACF1", "MAD1L1", "MAD2L1", "MAEA", "MAGED2", "MAIP1", "MAK16", "MAN1A1", "MAN1A2", "MAN2A1", "MAN2B1", "MANEA", "MANF", "MAP1A", "MAP1B", "MAP1S", "MAP2K1", "MAP3K7", "MAP4", "MAPK1", "MAPK14", "MAPK3", "MAPRE1", "MAPRE2", "MARC1", "MARCH5", "MARCKS", "MARCKSL1", "MARK2", "MARS", "MASTL", "MAT2A", "MAT2B", "MATR3", "MAU2", "MAVS", "MBD3", "MBOAT7", "MCAT", "MCCC1", "MCCC2", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "MCMBP", "MCTS1", "MCU", "MCUB", "MDC1", "MDH1", "MDH2", "MDN1", "ME1", "ME2", "MEAF6", "MECP2", "MECR", "MED1", "MED14", "MED17", "MED21", "MED23", "MED25", "MED4", "MEPCE", "MESD", "METAP1", "METAP2", "METTL1", "METTL13", "METTL7B", "METTL9", "MFAP1", "MFF", "MFN2", "MFSD10", "MFSD3", "MFSD8", "MGEA5", "MGST1", "MGST2", "MGST3", "MIA2", "MIA3", "MICU1", "MICU2", "MID1", "MIEF1", "MIF", "MIGA1", "MINDY3", "MIPEP", "MKI67", "MMAB", "MMS19", "MOCOS", "MOCS1", "MOGS", "MON1A", "MON2", "MORF4L1", "MORF4L2", "MOSPD2", "MOV10", "MPDU1", "MPG", "MPHOSPH10", "MPHOSPH6", "MPI", "MPP1", "MPP2", "MPP5", "MPP7", "MPRIP", "MPST", "MRE11", "MRFAP1", "MRI1", "MRM3", "MRPL1", "MRPL10", "MRPL11", "MRPL12", "MRPL14", "MRPL15", "MRPL19", "MRPL2", "MRPL20", "MRPL21", "MRPL22", "MRPL28", "MRPL37", "MRPL38", "MRPL39", "MRPL40", "MRPL41", "MRPL43", "MRPL44", "MRPL46", "MRPL47", "MRPL48", "MRPL50", "MRPL53", "MRPL58", "MRPL9", "MRPS11", "MRPS15", "MRPS16", "MRPS2", "MRPS22", "MRPS23", "MRPS25", "MRPS26", "MRPS27", "MRPS28", "MRPS31", "MRPS34", "MRPS35", "MRPS5", "MRPS6", "MRPS7", "MRPS9", "MRRF", "MRTO4", "MSH2", "MSH3", "MSH6", "MSI2", "MSMO1", "MSN", "MSTO1", "MTA1", "MTA2", "MTAP", "MTBP", "MTCH2", "MTDH", "MTERF3", "MTF2", "MTFP1", "MTFR1", "MTG1", "MTHFD1L", "MTHFD2", "MTIF2", "MTOR", "MTPAP", "MTPN", "MTR", "MTX1", "MTX2", "MUT", "MVD", "MXRA7", "MYBBP1A", "MYCBP", "MYCBP2", "MYG1", "MYH10", "MYH14", "MYH9", "MYO1B", "MYO1C", "MYO1D", "MYO6", "NAA10", "NAA15", "NAA16", "NAA40", "NAA50", "NADK2", "NADSYN1", "NAE1", "NAF1", "NAGK", "NAMPT", "NANS", "NAP1L1", "NAP1L4", "NAPA", "NAPG", "NARS", "NASP", "NAT10", "NAXE", "NBAS", "NBN", "NCAPD2", "NCAPD3", "NCAPG2", "NCAPH", "NCBP1", "NCBP3", "NCDN", "NCEH1", "NCK1", "NCKAP1", "NCKIPSD", "NCL", "NCLN", "NCOA5", "NCSTN", "NDC1", "NDUFA10", "NDUFA11", "NDUFA13", "NDUFA4", "NDUFA7", "NDUFA9", "NDUFAF2", "NDUFAF4", "NDUFB1", "NDUFB11", "NDUFB4", "NDUFB5", "NDUFB6", "NDUFB8", "NDUFB9", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NDUFV2", "NECAP1", "NECAP2", "NEFL", "NEFM", "NEK3", "NELFA", "NELFCD", "NELFE", "NEMF", "NES", "NFATC2IP", "NFKBIL1", "NFS1", "NFU1", "NHLRC2", "NIF3L1", "NIFK", "NIP7", "NIPBL", "NIPSNAP2", "NISCH", "NIT2", "NKRF", "NKTR", "NLE1", "NLN", "NMD3", "NME1", "NME2", "NMT1", "NNT", "NOA1", "NOB1", "NOC2L", "NOC3L", "NOC4L", "NOL10", "NOL11", "NOL6", "NOL7", "NOL8", "NOL9", "NOLC1", "NOM1", "NONO", "NOP10", "NOP14", "NOP16", "NOP2", "NOP53", "NOP56", "NOP58", "NOP9", "NOSIP", "NOTCH2", "NOVA2", "NPC1", "NPEPPS", "NPLOC4", "NPM1", "NPTN", "NRBP1", "NRDC", "NRDE2", "NRM", "NSA2", "NSD1", "NSD2", "NSD3", "NSDHL", "NSF", "NSFL1C", "NSL1", "NSUN2", "NSUN5", "NT5C3A", "NT5DC1", "NTMT1", "NTPCR", "NUB1", "NUBP2", "NUBPL", "NUCB1", "NUCB2", "NUCKS1", "NUDC", "NUDCD2", "NUDCD3", "NUDT1", "NUDT16", "NUDT16L1", "NUDT21", "NUDT5", "NUDT9", "NUFIP2", "NUMA1", "NUP107", "NUP133", "NUP153", "NUP155", "NUP188", "NUP35", "NUP37", "NUP43", "NUP50", "NUP54", "NUP62", "NUP85", "NUP88", "NUPL2", "NVL", "NXF1", "NXN", "OAT", "OBSL1", "OCIAD1", "OCLN", "OCRL", "ODR4", "OGDH", "OGFOD3", "OGT", "OLA1", "OPA1", "OPA3", "ORC2", "ORC3", "ORC5", "OS9", "OSBP", "OSBPL11", "OSBPL2", "OSBPL3", "OSBPL8", "OSBPL9", "OTUB1", "OXA1L", "OXCT1", "OXSR1", "P3H1", "P3H4", "P4HA1", "P4HA2", "P4HB", "PA2G4", "PABPC1", "PABPC4", "PABPN1", "PACSIN2", "PACSIN3", "PAF1", "PAFAH1B1", "PAFAH1B2", "PAFAH1B3", "PAICS", "PAIP2", "PAK1IP1", "PAK2", "PAK4", "PALLD", "PANK4", "PANX1", "PAPOLA", "PAPSS1", "PARG", "PARK7", "PARL", "PARN", "PARP1", "PARP2", "PARVA", "PATL1", "PAWR", "PAX6", "PAXBP1", "PBDC1", "PBK", "PBRM1", "PC", "PCBD1", "PCBP1", "PCBP2", "PCCA", "PCDH7", "PCID2", "PCK2", "PCM1", "PCMT1", "PCNA", "PCNP", "PCYOX1L", "PDAP1", "PDCD11", "PDCD4", "PDCD5", "PDCD6", "PDCD6IP", "PDCL3", "PDE4DIP", "PDHA1", "PDHB", "PDHX", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDK3", "PDLIM1", "PDLIM5", "PDLIM7", "PDP1", "PDPR", "PDRG1", "PDS5A", "PDS5B", "PDSS1", "PDSS2", "PDXDC1", "PDXK", "PDZD8", "PEBP1", "PECR", "PEF1", "PELO", "PELP1", "PEPD", "PES1", "PET100", "PEX14", "PEX19", "PEX5", "PEX6", "PFAS", "PFDN2", "PFDN5", "PFDN6", "PFKL", "PFKM", "PFKP", "PFN1", "PGAM1", "PGAM5", "PGD", "PGLS", "PGM1", "PGM2", "PGM3", "PGP", "PGRMC1", "PGRMC2", "PHAX", "PHB", "PHB2", "PHF10", "PHF14", "PHF3", "PHF5A", "PHF6", "PHF8", "PHGDH", "PHIP", "PHKA1", "PI4K2A", "PI4KA", "PI4KB", "PIAS2", "PIBF1", "PICALM", "PIGL", "PIK3C2A", "PIK3R4", "PIN1", "PIN4", "PIP4K2C", "PIR", "PISD", "PITPNA", "PITPNB", "PITRM1", "PJA2", "PKM", "PKMYT1", "PKN1", "PKN2", "PLA2G15", "PLAA", "PLCG1", "PLD3", "PLEC", "PLIN3", "PLOD1", "PLOD2", "PLPBP", "PLRG1", "PLS3", "PMF1", "PMPCA", "PMPCB", "PMS1", "PNKP", "PNN", "PNO1", "PNP", "PNPLA6", "PNPO", "PNPT1", "POFUT1", "POGZ", "POLA1", "POLA2", "POLD1", "POLD2", "POLDIP2", "POLDIP3", "POLE", "POLE2", "POLE3", "POLE4", "POLG", "POLR1A", "POLR1B", "POLR1C", "POLR1E", "POLR2B", "POLR2C", "POLR2D", "POLR2E", "POLR2G", "POLR2L", "POLR3A", "POLR3C", "POLR3E", "POLRMT", "POP1", "POP4", "POR", "PPA1", "PPA2", "PPAT", "PPFIA1", "PPHLN1", "PPIB", "PPID", "PPIE", "PPIF", "PPIG", "PPIL1", "PPIL2", "PPIL3", "PPIL4", "PPM1F", "PPM1G", "PPME1", "PPOX", "PPP1CA", "PPP1CB", "PPP1R10", "PPP1R12A", "PPP1R7", "PPP1R8", "PPP2R1A", "PPP2R1B", "PPP2R2A", "PPP2R5C", "PPP2R5D", "PPP2R5E", "PPP3CA", "PPP4R1", "PPP4R2", "PPP4R3A", "PPP5C", "PPP6R3", "PPT1", "PPT2", "PPWD1", "PQBP1", "PRAF2", "PRC1", "PRCC", "PRCP", "PRDX3", "PRDX4", "PRDX5", "PRDX6", "PREB", "PRELID3B", "PREP", "PRIM2", "PRKAA2", "PRKACA", "PRKAG1", "PRKAR1A", "PRKCD", "PRKCSH", "PRKDC", "PRKRA", "PRMT1", "PRMT5", "PRPF19", "PRPF3", "PRPF31", "PRPF4", "PRPF40A", "PRPF4B", "PRPF6", "PRPF8", "PRPS1", "PRPSAP1", "PRPSAP2", "PRRC1", "PRRC2A", "PRRC2C", "PSAP", "PSAT1", "PSIP1", "PSMA1", "PSMA4", "PSMA5", "PSMA6", "PSMB1", "PSMB2", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD1", "PSMD10", "PSMD11", "PSMD12", "PSMD13", "PSMD14", "PSMD3", "PSMD4", "PSMD7", "PSMD8", "PSMD9", "PSME1", "PSME2", "PSME3", "PSME4", "PSMF1", "PSMG1", "PSMG2", "PSPC1", "PTBP1", "PTCD1", "PTCD3", "PTDSS1", "PTGES2", "PTGES3", "PTGR2", "PTPA", "PTPMT1", "PTPN1", "PTPN11", "PTPN23", "PTPRF", "PTRH2", "PTRHD1", "PUDP", "PUF60", "PUM3", "PUS1", "PUS7", "PWP1", "PWP2", "PWWP2A", "PXMP4", "PYCR2", "PYCR3", "PYGB", "PYGL", "QARS", "QDPR", "QKI", "QRSL1", "QSOX2", "QTRT1", "QTRT2", "R3HCC1", "RAB11B", "RAB11FIP1", "RAB12", "RAB13", "RAB14", "RAB1A", "RAB1B", "RAB23", "RAB24", "RAB3GAP1", "RAB3GAP2", "RAB5A", "RAB5B", "RAB5C", "RAB7A", "RAB8A", "RAB9A", "RABEP1", "RABGAP1", "RABGEF1", "RABGGTB", "RABL3", "RABL6", "RAC1", "RACGAP1", "RACK1", "RAD21", "RAD23B", "RAD50", "RAE1", "RAI14", "RALA", "RALY", "RAN", "RANBP1", "RANBP2", "RANBP3", "RANBP6", "RANBP9", "RANGAP1", "RAP1GDS1", "RAPGEF2", "RARS", "RARS2", "RAVER1", "RBBP4", "RBBP5", "RBBP6", "RBBP7", "RBM10", "RBM12", "RBM12B", "RBM14", "RBM15", "RBM17", "RBM19", "RBM22", "RBM25", "RBM26", "RBM27", "RBM28", "RBM3", "RBM34", "RBM39", "RBM4", "RBM42", "RBM45", "RBM5", "RBM6", "RBM7", "RBM8A", "RBMX", "RBMXL1", "RCC1", "RCL1", "RCN1", "RCN2", "RCOR1", "RDH13", "RDH14", "RDX", "RECQL", "REEP2", "REEP4", "REEP5", "REPS1", "RER1", "RETSAT", "REXO2", "REXO4", "RFC1", "RFC2", "RFC3", "RFC4", "RFC5", "RFK", "RFLNB", "RFT1", "RFX1", "RHBDD2", "RHOT2", "RIC8A", "RIF1", "RINT1", "RIOK2", "RIOX2", "RIPK1", "RMDN1", "RMDN2", "RMDN3", "RMI1", "RMND1", "RNASEH2A", "RNASEH2C", "RNF14", "RNF2", "RNF20", "RNF213", "RNF40", "RNGTT", "RNH1", "RNMT", "RNPEP", "RNPS1", "ROCK2", "RPA1", "RPA2", "RPAP1", "RPAP3", "RPF1", "RPF2", "RPL10", "RPL10A", "RPL12", "RPL13", "RPL13A", "RPL14", "RPL17", "RPL18", "RPL18A", "RPL19", "RPL21", "RPL22", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL28", "RPL29", "RPL3", "RPL30", "RPL32", "RPL34", "RPL35", "RPL36", "RPL36A", "RPL37A", "RPL38", "RPL4", "RPL5", "RPL6", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPLP0", "RPLP1", "RPLP2", "RPN1", "RPN2", "RPP14", "RPP25L", "RPP30", "RPP40", "RPRD1A", "RPRD1B", "RPRD2", "RPS10", "RPS11", "RPS12", "RPS13", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS23", "RPS24", "RPS25", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS5", "RPS6", "RPS6KA1", "RPS6KA3", "RPS7", "RPS8", "RPSA", "RRBP1", "RREB1", "RRM1", "RRM2", "RRM2B", "RRP1", "RRP12", "RRP15", "RRP1B", "RRP36", "RRP7A", "RRP8", "RRP9", "RRS1", "RSF1", "RSL1D1", "RSL24D1", "RSU1", "RTCA", "RTCB", "RTF1", "RTN2", "RTN3", "RTN4", "RTRAF", "RUVBL1", "RUVBL2", "S100A10", "S100A11", "SACM1L", "SAE1", "SAFB", "SAFB2", "SALL2", "SAMHD1", "SAMM50", "SAP18", "SAP30", "SAP30BP", "SAR1A", "SAR1B", "SARM1", "SARNP", "SARS", "SARS2", "SART1", "SART3", "SBDS", "SC5D", "SCAF1", "SCAF11", "SCAF4", "SCAF8", "SCAMP2", "SCAMP3", "SCARB1", "SCARB2", "SCCPDH", "SCD", "SCLY", "SCML2", "SCO2", "SCOC", "SCP2", "SCPEP1", "SCRIB", "SCRN1", "SCRN3", "SCYL1", "SDAD1", "SDCBP", "SDF4", "SDHA", "SDHB", "SDR39U1", "SEC11A", "SEC13", "SEC16A", "SEC23A", "SEC23B", "SEC23IP", "SEC24A", "SEC24B", "SEC24C", "SEC31A", "SEC61A1", "SEC61B", "SEC62", "SEC63", "SELENBP1", "SENP3", "SEPHS1", "SEPT11", "SEPT2", "SEPT3", "SEPT6", "SEPT7", "SEPT9", "SERBP1", "SERPINB1", "SERPINB6", "SERPINH1", "SET", "SETD1A", "SETDB1", "SF1", "SF3A1", "SF3A2", "SF3A3", "SF3B1", "SF3B2", "SF3B3", "SF3B4", "SF3B6", "SFPQ", "SFSWAP", "SFXN1", "SFXN2", "SFXN4", "SGF29", "SGPL1", "SGTA", "SH3BGRL2", "SH3BGRL3", "SH3GL1", "SH3GLB1", "SH3GLB2", "SHCBP1", "SHMT1", "SHMT2", "SHOC2", "SIN3A", "SIRT1", "SKIV2L", "SKIV2L2", "SKP1", "SKP2", "SLAIN2", "SLC12A2", "SLC12A7", "SLC16A1", "SLC18B1", "SLC19A1", "SLC1A5", "SLC25A10", "SLC25A12", "SLC25A13", "SLC25A17", "SLC25A19", "SLC25A20", "SLC25A24", "SLC25A25", "SLC25A26", "SLC25A3", "SLC25A32", "SLC25A4", "SLC25A42", "SLC25A44", "SLC25A5", "SLC25A6", "SLC27A4", "SLC2A1", "SLC30A7", "SLC33A1", "SLC35B2", "SLC35F2", "SLC38A2", "SLC39A10", "SLC39A11", "SLC39A14", "SLC3A2", "SLC4A1AP", "SLC4A2", "SLC4A7", "SLC7A5", "SLC9A3R1", "SLFN11", "SLIRP", "SLK", "SLTM", "SMAP1", "SMARCA1", "SMARCA4", "SMARCA5", "SMARCAD1", "SMARCB1", "SMARCC1", "SMARCC2", "SMARCD1", "SMARCD2", "SMARCE1", "SMC1A", "SMC2", "SMC3", "SMC4", "SMC5", "SMC6", "SMCHD1", "SMDT1", "SMG1", "SMG8", "SMIM12", "SMIM4", "SMN1*", "SMNDC1", "SMPD4", "SMS", "SMU1", "SMYD3", "SNAP29", "SNAP47", "SND1", "SNRNP200", "SNRNP40", "SNRNP70", "SNRPA", "SNRPA1", "SNRPB2", "SNRPC", "SNRPD2", "SNRPD3", "SNW1", "SNX1", "SNX17", "SNX2", "SNX27", "SNX5", "SNX6", "SNX8", "SNX9", "SOAT1", "SOD2", "SON", "SORBS3", "SORD", "SORT1", "SPAG9", "SPART", "SPAST", "SPATA5", "SPATA5L1", "SPATS2L", "SPC24", "SPCS2", "SPDL1", "SPECC1", "SPEN", "SPHK2", "SPNS1", "SPPL2A", "SPR", "SPTAN1", "SPTBN1", "SPTBN2", "SPTLC1", "SQLE", "SQOR", "SRCAP", "SRFBP1", "SRI", "SRM", "SRP14", "SRP19", "SRP54", "SRP68", "SRPK1", "SRPRB", "SRRM1", "SRRM2", "SRRT", "SRSF1", "SRSF10", "SRSF11", "SRSF2", "SRSF3", "SRSF4", "SRSF5", "SRSF6", "SRSF7", "SRSF9", "SSB", "SSBP1", "SSR1", "SSR4", "SSRP1", "STAG1", "STAG2", "STAM", "STAMBP", "STARD3", "STARD3NL", "STARD7", "STAT1", "STAT3", "STAU1", "STIP1", "STK26", "STK4", "STMN1", "STOM", "STOML2", "STRAP", "STRIP1", "STRN", "STT3B", "STUB1", "STX10", "STX12", "STX18", "STX4", "STX5", "STX6", "STX7", "STX8", "STXBP2", "STXBP3", "STXBP4", "SUB1", "SUCLA2", "SUCLG1", "SUCLG2", "SUGP1", "SUGP2", "SUGT1", "SULT2A1", "SUMF2", "SUMO2", "SUN1", "SUN2", "SUPT16H", "SUPT5H", "SUPT6H", "SUPV3L1", "SURF4", "SURF6", "SUZ12", "SV2A", "SYAP1", "SYMPK", "SYNCRIP", "SYNE2", "SYNGR2", "SYNJ2BP", "TAB1", "TACC3", "TADA3", "TAF10", "TAF15", "TAGLN2", "TALDO1", "TAMM41", "TAP1", "TARDBP", "TARS", "TARS2", "TARSL2", "TATDN1", "TBC1D13", "TBC1D15", "TBC1D4", "TBC1D9B", "TBCA", "TBCB", "TBL1XR1", "TBL2", "TBL3", "TBPL1", "TBRG4", "TCAF1", "TCEA1", "TCERG1", "TCOF1", "TCP11L1", "TCTN3", "TDRKH", "TECR", "TEDC1", "TEFM", "TELO2", "TERF2IP", "TES", "TEX10", "TEX264", "TFAM", "TFAP4", "TFCP2", "TFG", "TFIP11", "TFRC", "TGFBRAP1", "TGOLN2", "THADA", "THAP11", "THEM6", "THOC1", "THOC2", "THOC3", "THOC5", "THOC6", "THOP1", "THRAP3", "THUMPD1", "THUMPD3", "THYN1", "TIAL1", "TIGAR", "TIMELESS", "TIMM13", "TIMM17A", "TIMM17B", "TIMM23", "TIMM44", "TIMM50", "TIMM9", "TIMMDC1", "TJP1", "TJP2", "TKFC", "TKT", "TLE3", "TLN1", "TM7SF2", "TM9SF3", "TMA16", "TMA7", "TMCO1", "TMED10", "TMED2", "TMEM109", "TMEM115", "TMEM126A", "TMEM126B", "TMEM131", "TMEM161A", "TMEM165", "TMEM167A", "TMEM192", "TMEM201", "TMEM205", "TMEM209", "TMEM214", "TMEM230", "TMEM245", "TMEM259", "TMEM35B", "TMEM70", "TMEM87A", "TMEM97", "TMF1", "TMOD3", "TMX1", "TMX2", "TMX4", "TNFAIP8", "TNKS1BP1", "TNPO1", "TNPO2", "TNPO3", "TOE1", "TOLLIP", "TOM1L2", "TOMM20", "TOMM22", "TOMM34", "TOMM40", "TOMM5", "TOMM70", "TOP1", "TOP2A", "TOP2B", "TOR1A", "TOR1AIP1", "TOR1B", "TOX4", "TP53", "TP53BP1", "TPBG", "TPD52", "TPD52L2", "TPI1", "TPM1", "TPM3", "TPM4", "TPP2", "TPR", "TPRKB", "TPT1", "TPX2", "TRA2A", "TRA2B", "TRABD", "TRAP1", "TRAPPC11", "TRAPPC3", "TRAPPC4", "TRAPPC5", "TRIM21", "TRIM24", "TRIM25", "TRIM26", "TRIM27", "TRIM28", "TRIM32", "TRIM33", "TRIP12", "TRIP13", "TRIP4", "TRIR", "TRIT1", "TRMT10C", "TRMT11", "TRMT112", "TRMT1L", "TRMT2A", "TRMT6", "TRMT61A", "TRMU", "TROVE2", "TRRAP", "TRUB1", "TSFM", "TSG101", "TSN", "TSNAX", "TSPAN3", "TSPAN6", "TSPYL1", "TSR1", "TSTA3", "TTC1", "TTC19", "TTC27", "TTC37", "TTC38", "TTC4", "TTC7B", "TTF2", "TTK", "TTLL12", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUBGCP2", "TUFM", "TWF1", "TWF2", "TWISTNB", "TXLNA", "TXLNG", "TXNDC15", "TXNDC5", "TXNDC9", "TXNL1", "TXNRD1", "TYSND1", "U2AF1", "U2AF2", "U2SURP", "UAP1", "UBA1", "UBA2", "UBA3", "UBA5", "UBA6", "UBAC1", "UBAC2", "UBAP2", "UBAP2L", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UBE2O", "UBE2S", "UBE2V1", "UBE3C", "UBE4A", "UBFD1", "UBIAD1", "UBLCP1", "UBQLN1", "UBQLN4", "UBR4", "UBR5", "UBR7", "UBTF", "UBXN1", "UBXN4", "UBXN6", "UCHL5", "UCK2", "UFC1", "UFD1", "UFL1", "UFSP2", "UGDH", "UGGT1", "UGP2", "UGT8", "UHRF1", "UMPS", "UNC45A", "UNG", "UPF1", "UPF2", "UPF3B", "UQCC1", "UQCC2", "UQCRC1", "UQCRC2", "UQCRFS1", "UQCRQ", "UROD", "USMG5", "USO1", "USP1", "USP10", "USP11", "USP14", "USP15", "USP22", "USP24", "USP28", "USP38", "USP39", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP11", "UTP14A", "UTP15", "UTP18", "UTP20", "UTP4", "UTP6", "UTRN", "UXT", "VAMP7", "VANGL1", "VAPA", "VAPB", "VARS1", "VARS2", "VBP1", "VCL", "VCP", "VDAC2", "VDAC3", "VEZT", "VIM", "VIRMA", "VKORC1L1", "VMP1", "VPS13D", "VPS25", "VPS26A", "VPS29", "VPS33A", "VPS35", "VPS36", "VPS45", "VPS4A", "VPS4B", "VPS50", "VPS51", "VPS53", "VPS72", "VRK1", "VRK2", "VTA1", "VWA8", "WAPL", "WARS", "WARS2", "WASF2", "WASHC3", "WASHC4", "WASHC5", "WBP11", "WBP2", "WDHD1", "WDR1", "WDR12", "WDR18", "WDR3", "WDR33", "WDR34", "WDR36", "WDR4", "WDR45B", "WDR46", "WDR5", "WDR6", "WDR61", "WDR7", "WDR74", "WDR77", "WDR82", "WDR89", "WIZ", "WLS", "WNK1", "WRN", "WTAP", "XAB2", "XPNPEP1", "XPNPEP3", "XPO1", "XPO4", "XPO5", "XPOT", "XRCC1", "XRCC5", "XRCC6", "XRN2", "YARS", "YARS2", "YBX1", "YIF1A", "YIF1B", "YIPF3", "YIPF4", "YIPF5", "YKT6", "YLPM1", "YME1L1", "YTHDC1", "YTHDF2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "YY1", "ZADH2", "ZC3H11A", "ZC3H14", "ZC3H15", "ZC3H18", "ZC3H4", "ZC3HAV1", "ZC3HC1", "ZCCHC11", "ZCCHC3", "ZCCHC8", "ZDHHC13", "ZFPL1", "ZFR", "ZFYVE16", "ZMAT2", "ZMYM1", "ZMYM2", "ZMYM4", "ZMYND8", "ZNF281", "ZNF318", "ZNF326", "ZNF512", "ZNF512B", "ZNF622", "ZNF638", "ZNF644", "ZNF687", "ZPR1", "ZW10", "ZYX"], "leading_proteins": ["ACBD3", "ACTN1", "ACTN4", "APLP2", "APP", "ARHGAP1", "ARHGAP10", "ATP13A1", "ATP5J2", "ATP6V0A1", "ATP6V0A2", "B4GALT1", "B4GALT3", "BICD2", "CALCOCO1", "CANT1", "CCDC22", "CCDC93", "CD2AP", "CDK4", "CENPH", "CENPU", "CEP131", "CERS2", "CHST14", "CLN6", "CLTC", "CLUH", "CNNM4", "COLEC12", "COPB2", "CPD", "CRTAP", "CTSA", "CUTA", "CYB5B", "DCUN1D4", "DDX56", "DNAJB12", "DNTTIP2", "DYM", "EEA1", "EFCAB14", "EIF2B2", "EMD", "FAM114A2", "FAM98A", "FKRP", "FLII", "FLOT1", "FNBP1", "FUCA1", "G6PD", "GAA", "GAK", "GAL", "GCC1", "GCC2", "GLB1", "GLG1", "GOLGA2", "GOLGA5", "GOLIM4", "GOLM1", "GPR107", "GPR108", "GTPBP4", "HMOX2", "HOOK2", "HOOK3", "IGF2R", "IMPAD1", "INA", "INPP4A", "IQGAP3", "ISOC1", "ITSN2", "JAM3", "KIAA0319L", "KIAA1147", "KIAA1468", "KIAA2013", "KIF3A", "KIF5B", "KLHDC4", "KNSTRN", "KRR1", "LAPTM4A", "LAS1L", "LBR", "LEMD3", "LMBRD1", "LMNB1", "LMNB2", "LRWD1", "MAD1L1", "MAN1A2", "MANEA", "MAPRE1", "MCUB", "MFSD10", "MFSD8", "MID1", "MPRIP", "MYCBP2", "MYH10", "MYH9", "NBAS", "NDC1", "NDUFB4", "NEFL", "NEFM", "NELFCD", "NIFK", "NOC2L", "NOL8", "NPC1", "NUCB1", "NUCB2", "NUP107", "PAFAH1B3", "PCM1", "PDE4DIP", "PDRG1", "PIBF1", "PLA2G15", "PPFIA1", "PPOX", "PPT1", "PPT2", "PRCP", "PSAP", "PSMD11", "PSMG1", "PTGR2", "PTPRF", "RAB24", "RANBP2", "RBM39", "RFC3", "RRP15", "RSL1D1", "SCAMP2", "SCARB1", "SCCPDH", "SCPEP1", "SDF4", "SEC13", "SEC23B", "SET", "SLC18B1", "SLC35F2", "SLC4A7", "SLC7A5", "SNX2", "SORT1", "SPAG9", "SPECC1", "SPPL2A", "SPTAN1", "SPTBN1", "STX10", "STX6", "STX7", "SUN2", "SURF4", "SURF6", "TACC3", "TAP1", "TEDC1", "TFRC", "TGFBRAP1", "TGOLN2", "TM9SF3", "TMEM131", "TMEM165", "TMEM192", "TMEM201", "TMEM205", "TMEM87A", "TOM1L2", "TPM1", "TPM3", "TPM4", "TPR", "TRIM32", "TSPAN3", "UBIAD1", "USP47", "VIM", "VWA8", "YIPF5", "ZMYM1"]} \ No newline at end of file