| Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size |
| Metabolism of porphyrins 0.7774181193536526 2.307884439192395 0.0210055647695752 0.9999999999998624 1.0 9 Q7KZN9,P50336,P09601,P22830,P30519 5 |
| Sphingolipid de novo biosynthesis 0.7649268729422535 2.2480036987519822 0.0245759540666383 0.9999999999999992 1.0 9 Q96G23,P51648,O95470 3 |
| Class i peroxisomal membrane protein import 0.7629319370757176 2.2184456659111538 0.026524460390443 1.0 1.0 10 P28288,O75381,Q9NR77,Q9Y3D6,P51648,P40855,Q8TB36,O43808 8 |
| Transport of inorganic cations anions and amino acids oligopeptides 0.7722243108976502 2.203873331976798 0.0275332535137031 1.0 1.0 13 Q15758,P30626,P04920,P30825,Q9Y6M7,Q70HW3,Q9UPY5,P08195,Q9UBX3 9 |
| Alpha oxidation of phytanate 0.862818259395383 2.1754278711310646 0.0295980678045446 1.0 1.0 5 O14975,P51648 2 |
| Heparan sulfate heparin hs gag metabolism 0.8462103048150009 2.1063581312641286 0.0351732552940819 1.0 1.0 5 Q96L58,P54802 2 |
| Mitochondrial fatty acid beta oxidation of unsaturated fatty acids 0.8839568801521867 2.0988249368082244 0.0358323357520333 1.0 1.0 4 P55084,P40939,P42126 3 |
| Synthesis of very long chain fatty acyl coas 0.7300454582808583 2.078537319438537 0.0376598973215023 1.0 1.0 9 Q9P035,O60488,Q9UKU0,Q53GQ0 4 |
| Metabolism of steroid hormones 0.8355941628161352 2.061943357115414 0.039213129026246 1.0 1.0 5 P30536,Q8NBQ5 2 |
| Synthesis of pips at the golgi membrane 0.7210942395796924 2.054651701690136 0.0399126580872135 1.0 1.0 8 Q8NEB9 1 |
| Platelet calcium homeostasis 0.8271487472248571 2.0264648230173345 0.0427171739923621 1.0 1.0 5 P30626,P20020,Q13586,P16615 4 |
| Cobalamin cbl vitamin b12 transport and metabolism 0.8605668695598594 2.00384387426336 0.0450867873316038 1.0 1.0 4 Q96EY8,P22033 2 |
| Defects in cobalamin b12 metabolism 0.8605668695598594 2.00384387426336 0.0450867873316038 1.0 1.0 4 Q96EY8,P22033 2 |
| Ion transport by p type atpases 0.7253090211002136 1.995477827568378 0.0459907900489962 1.0 1.0 12 P30626,P05023,P98194,P23634,P35670,P05026,Q9HD20,P16615,P20020,P54709 10 |
| Heme degradation 0.9368368479778846 1.9735437305285937 0.0484336473967288 1.0 1.0 3 P09601 1 |
| Cardiac conduction 0.7136916141488248 1.938111423801808 0.0526096300223484 1.0 1.0 12 P30626,P23634,P05026,P16615,O43865,Q13586,P20020,P54709 8 |
| Ion homeostasis 0.7136916141488248 1.938111423801808 0.0526096300223484 1.0 1.0 12 P30626,P23634,P05026,P16615,O43865,Q13586,P20020,P54709 8 |
| Post translational modification synthesis of gpi anchored proteins 0.6973849292321932 1.9168703984803264 0.0552543985586602 1.0 1.0 9 Q9Y2B2,Q92643 2 |
| Formation of fibrin clot clotting cascade 0.9201845929344106 1.9095212556305885 0.0561948823966764 1.0 1.0 3 P42785 1 |
| Amino acid transport across the plasma membrane 0.7543441709002968 1.908319410637263 0.0563499457146927 1.0 1.0 6 Q15758,Q9UPY5,P30825 3 |
| O linked glycosylation of mucins 0.8354300887395436 1.9007925162142283 0.0573291947123602 1.0 1.0 4 Q8N4A0,Q10472 2 |
| Synaptic adhesion like molecules 0.75047517406017 1.890928459617205 0.0586338947702544 1.0 1.0 6 O95197,P41440 2 |
| Basigin interactions 0.7450540292952872 1.8665107218089971 0.0619699454077902 1.0 1.0 6 Q9UPY5,P35613,P08195,P05026 4 |
| Reduction of cytosolic ca levels 0.8268864933417982 1.865544239843963 0.0621051571624735 1.0 1.0 4 P30626,P20020,P16615 3 |
| Pink1 prkn mediated mitophagy 0.7425562410962073 1.8552408005957064 0.0635618477120483 1.0 1.0 6 P21796 1 |
| Transport of vitamins nucleosides and related molecules 0.6747042692290716 1.8231055244179368 0.068287410054731 1.0 1.0 8 P12235,P12236,Q99808 3 |
| Attachment of gpi anchor to upar 0.7745718609434871 1.8027927966703192 0.0714207618829525 1.0 1.0 5 Q92643 1 |
| Heme biosynthesis 0.7297016929779475 1.7970503296444598 0.0723276300603203 1.0 1.0 6 Q7KZN9,P22830,P50336 3 |
| Incretin synthesis secretion and inactivation 0.772432930245337 1.7935954316129596 0.0728777662431077 1.0 1.0 5 P67812 1 |
| Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.772432930245337 1.7935954316129596 0.0728777662431077 1.0 1.0 5 P67812 1 |
| Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane 0.7694167901403615 1.7806137137357885 0.0749755778827463 1.0 1.0 5 P12235,P12236,Q99808 3 |
| Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.672752978859414 1.7332092048921732 0.0830584915439869 1.0 1.0 12 P09601,P50402,O43681 3 |
| Diseases associated with n glycosylation of proteins 0.6556934424397053 1.726579584080437 0.0842431951218729 1.0 1.0 8 O75340,Q9BV10,Q9BT22,Q9Y672 4 |
| Hs gag degradation 0.8728618992019552 1.7257866132346378 0.0843858090406997 1.0 1.0 3 P54802 1 |
| Wax and plasmalogen biosynthesis 0.7926442612555544 1.7232013605684342 0.0848521177900507 1.0 1.0 4 O00116,O15228,Q6IAN0 3 |
| Ra biosynthesis pathway 0.7091905514607617 1.7035573451161865 0.0884638160749169 1.0 1.0 6 O75911,Q9HBH5,Q9BTZ2,Q8TC12 4 |
| Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.708213694634886 1.6990856805312051 0.089303041026675 1.0 1.0 6 P55084,P49748,P40939,P11310 4 |
| Plasma lipoprotein assembly 0.8637243431042962 1.6900300017511092 0.0910222150458281 1.0 1.0 3 P07237 1 |
| Synthesis of bile acids and bile salts via 7alpha hydroxycholesterol 0.7841789375665585 1.6877627102693429 0.0914567884247228 1.0 1.0 4 P51659,O14975 2 |
| Alpha linolenic omega3 and linoleic omega6 acid metabolism 0.7016558018657514 1.680939599688136 0.0927746471860648 1.0 1.0 7 Q15067,P33121,P51659,O95864 4 |
| Metabolism of folate and pterines 0.6466101414414307 1.680138953981607 0.0929302833655767 1.0 1.0 8 Q9H2D1,P34896,P00374 3 |
| Cristae formation 0.6903107049442495 1.6664293881768637 0.0956279214513931 1.0 1.0 20 Q5XKP0,Q13505,Q6UXV4,P24539,Q9Y512,Q9NX63,Q9BUR5,P36542,O75964 9 |
| Beta oxidation of pristanoyl coa 0.7780536027497597 1.6620627584739345 0.0965001917161787 1.0 1.0 4 P51659,O15254 2 |
| Acyl chain remodelling of pc 0.7759830452779193 1.6533648017176137 0.0982566418655443 1.0 1.0 4 Q6P1A2 1 |
| Sulfide oxidation to sulfate 0.8296290673685669 1.555936351463232 0.119723228223616 1.0 1.0 3 Q9UBX3 1 |
| Downregulation of erbb4 signaling 0.8294770206022236 1.5553362458729938 0.1198660092460937 1.0 1.0 3 P46934,Q96J02 2 |
| Integrin cell surface interactions 0.7520337164720048 1.5523963961360594 0.1205674052455954 1.0 1.0 4 Q08722 1 |
| Depolymerisation of the nuclear lamina 0.6218955568172233 1.5326997669621714 0.125349846633022 1.0 1.0 9 Q9Y2U8,P06493,P42167,Q8NC56,P50402,P02545 6 |
| Mitochondrial calcium ion transport 0.6557724451014608 1.5303284904635834 0.1259354395665481 1.0 1.0 18 Q9NWR8,P45880,O95202,Q9Y4W6,Q9Y277,P21796,Q8NE86,Q10713,Q8WWC4,Q96TA2 10 |
| Slc mediated transmembrane transport 0.6884034879888571 1.5263584925164442 0.1269206088297259 1.0 1.0 27 Q15758,P30626,Q9H936,P04920,P30825,Q70HW3,Q9UPY5,Q9Y6M7,P11166,P08195,P12236,Q99808,P35613,Q9UBX3,P12235 15 |
| Peptide ligand binding receptors 0.668483092425908 1.5253218106968278 0.1271788502683883 1.0 1.0 7 Q9NRV9,Q9NZJ7 2 |
| Class a 1 rhodopsin like receptors 0.668483092425908 1.5253218106968278 0.1271788502683883 1.0 1.0 7 Q9NRV9,Q9NZJ7 2 |
| Synthesis secretion and inactivation of glucose dependent insulinotropic polypeptide gip 0.8170940486386775 1.5064088905142077 0.1319622398157847 1.0 1.0 3 P67812 1 |
| Synthesis secretion and deacylation of ghrelin 0.8170940486386775 1.5064088905142077 0.1319622398157847 1.0 1.0 3 P67812 1 |
| Peroxisomal lipid metabolism 0.6326827508985716 1.489570528558391 0.1363371959405883 1.0 1.0 14 P51659,A8MXV4,P51648,Q15067,O14975,O43808,O15254 7 |
| Long term potentiation 0.7004381574095359 1.480175372743178 0.1388264509095429 1.0 1.0 5 Q14168 1 |
| Vitamin b5 pantothenate metabolism 0.6586661286061162 1.4702439811548005 0.141495686922199 1.0 1.0 6 P22413 1 |
| Protein protein interactions at synapses 0.6221369605358587 1.4352774507420791 0.1512080507661801 1.0 1.0 14 Q9Y2J2,P41440,Q14168,O95197,O75955 5 |
| Mucopolysaccharidoses 0.7192447733560858 1.4132430334966268 0.1575842774005211 1.0 1.0 4 P54802 1 |
| Tysnd1 cleaves peroxisomal proteins 0.6834137749127853 1.4051667459617283 0.1599717001091534 1.0 1.0 5 O00116,P51659,Q15067 3 |
| Rho gtpases activate nadph oxidases 0.6420894132681777 1.4002255991867971 0.1614457723465443 1.0 1.0 7 Q8NEB9 1 |
| Formation of atp by chemiosmotic coupling 0.5994585580237987 1.396144607098026 0.1626709534058084 1.0 1.0 10 P24539,P36542,O75964 3 |
| Signaling by retinoic acid 0.6096565989437077 1.390216805101722 0.1644630518906384 1.0 1.0 13 O75911,P50416,Q8NBN7,Q9HBH5,Q9BTZ2,Q8TC12 6 |
| Adp signalling through p2y purinoceptor 1 0.7133798351299958 1.3882662042208658 0.165055999213691 1.0 1.0 4 P29992,Q16539,P12931 3 |
| Phase i functionalization of compounds 0.6156483349990185 1.3824208173839965 0.1668425278180931 1.0 1.0 15 Q16850,P07099,O43169 3 |
| P38mapk events 0.7857369255150544 1.3821323554412774 0.1669310654368829 1.0 1.0 3 Q16539,P12931 2 |
| Gpcr ligand binding 0.5929393552455404 1.3819331620675055 0.1669922244629216 1.0 1.0 9 P42892,Q9NRV9,Q9NZJ7 3 |
| Signalling to ras 0.7118080253418209 1.3815689082602851 0.1671041061097735 1.0 1.0 4 P12931,Q16539 2 |
| Endosomal vacuolar pathway 0.7727416798732187 1.3305283740470548 0.1833442440833019 1.0 1.0 3 P10321,Q9UIQ6 2 |
| Ca2 pathway 0.6943563728598583 1.3071306140418957 0.1911683555938907 1.0 1.0 4 Q08209,Q9UBI6,Q9HCE1 3 |
| Signal amplification 0.5742446526499446 1.3036614876968189 0.1923490259364584 1.0 1.0 8 P29992,Q16539,P12931 3 |
| Beta oxidation of decanoyl coa to octanoyl coa coa 0.6574864901007762 1.290527455428366 0.1968675855028192 1.0 1.0 5 P55084,P40939,P11310 3 |
| Beta oxidation of octanoyl coa to hexanoyl coa 0.6574864901007762 1.290527455428366 0.1968675855028192 1.0 1.0 5 P55084,P40939,P11310 3 |
| Rab geranylgeranylation 0.6195598439428459 1.2887900296037895 0.1974710931913361 1.0 1.0 21 Q9UL25,P20338,P61020,Q9H0U4,P62820,P61106,Q13636,Q969Q5,P51148,P51149,Q14964,Q6IQ22,Q9NP72,P61026,P51153 15 |
| Free fatty acids regulate insulin secretion 0.7572107765451881 1.2688341300209625 0.2045002294974467 1.0 1.0 3 O60488,O95573 2 |
| Antigen activates b cell receptor bcr leading to generation of second messengers 0.6794770932927348 1.2435936616321608 0.2136491501444362 1.0 1.0 4 Q13586 1 |
| Synthesis of pg 0.7483359746434458 1.2335897155534912 0.2173558272338527 1.0 1.0 3 Q8WUK0,Q8IV08 2 |
| Processing of smdt1 0.576398371911033 1.217047635043946 0.2235860924598323 1.0 1.0 13 Q9NWR8,Q9Y4W6,Q10713,Q8NE86,Q8WWC4,Q96TA2 6 |
| Pi metabolism 0.5896641432599851 1.2097899178346607 0.2263595159275815 1.0 1.0 17 Q8IY17,Q8NEB9,Q10713,Q8TBX8 4 |
| Vitamin d calciferol metabolism 0.7342900455112381 1.1778570270165762 0.2388536093801483 1.0 1.0 3 P38435 1 |
| Mitochondrial protein import 0.636563220723019 1.1589037000163438 0.2464954405666741 1.0 1.0 33 O60830,Q5JRX3,Q3ZCQ8,O43615,O14925,Q13505,Q9NS69,Q10713,P21796,Q9Y512,Q9NX63,P12235 12 |
| Translation of sars cov 2 structural proteins 0.5719050656890832 1.155367109263864 0.2479401249104649 1.0 1.0 15 Q16706,P61803,P46977,P27824,Q10472 5 |
| Cell surface interactions at the vascular wall 0.5761572900927109 1.1210796977833073 0.2622539396826999 1.0 1.0 18 P05026,P14174,Q9UPY5,P08195,Q08722,P35613,Q9UNN8 7 |
| Downregulation of smad2 3 smad4 transcriptional activity 0.5834802803838486 1.1197723894284404 0.2628107680292211 1.0 1.0 7 Q13547,Q13573,P09874,Q96PU5,O75376 5 |
| Arachidonate production from dag 0.7136870415608634 1.0963083229103163 0.2729438683285141 1.0 1.0 3 Q8NCG7 1 |
| Neurotransmitter clearance 0.9600760456273756 1.070400688751925 0.2844389894050867 1.0 1.0 2 P21964 1 |
| Maturation of sars cov 2 spike protein 0.5379444397987272 1.053684998800805 0.2920271592264838 1.0 1.0 11 P46977,P61803,P27824 3 |
| Regulation of tp53 activity through acetylation 0.5386018882615925 1.0380901995211251 0.2992280637235502 1.0 1.0 12 Q8WXI9,Q9NPI1 2 |
| Regulation of innate immune responses to cytosolic dna 0.6311902748984574 1.0377527853632873 0.2993851632084261 1.0 1.0 4 P19474 1 |
| Notch hlh transcription pathway 0.6307631433830503 1.0359395701361946 0.3002303355629609 1.0 1.0 4 Q13573,O75376 2 |
| Sulfur amino acid metabolism 0.5320901146422974 1.0228746762072376 0.3063671043003895 1.0 1.0 11 Q13126 1 |
| Sphingolipid metabolism 0.5816044116922787 1.0216614944922595 0.3069411415763599 1.0 1.0 25 O95470,Q9NXE4,P51648,O43681,Q16880,Q96G23,Q9NZJ7 7 |
| Inla mediated entry of listeria monocytogenes into host cells 0.6941362916006251 1.0192956250901728 0.3080626403458479 1.0 1.0 3 O60716,P12931 2 |
| Chylomicron assembly 0.94423320659062 1.0160836039647096 0.3095895761121263 1.0 1.0 2 P07237 1 |
| Peroxisomal protein import 0.5680126432684659 1.0058501608859087 0.314487653778102 1.0 1.0 22 O00116,O75874,P34913,P51659,A8MXV4,O75381,Q9BTZ2,O15228,Q15067,O14975,O15254 11 |
| Mitophagy 0.5242354688648316 1.0005541795661983 0.3170423917134539 1.0 1.0 10 P21796 1 |
| Intra golgi traffic 0.5411766594739806 0.9952004836930436 0.3196387665997353 1.0 1.0 15 Q16706,Q8TBA6,O95249,Q14746,O00461,Q13190,O15498 7 |
| Regulation of insulin secretion 0.5322612944234518 0.9859901897860258 0.3241379269119502 1.0 1.0 13 O60488 1 |
| Detoxification of reactive oxygen species 0.5156347288156224 0.9742376430245742 0.3299385581101917 1.0 1.0 9 P07237 1 |
| Syndecan interactions 0.6144578313253053 0.96690467344592 0.333591690144996 1.0 1.0 4 Q9Y296,P12814,O14936 3 |
| Beta oxidation of lauroyl coa to decanoyl coa coa 0.6134547567336279 0.9626710562988005 0.3357126262045504 1.0 1.0 4 P55084,P40939 2 |
| Beta oxidation of hexanoyl coa to butanoyl coa 0.6134547567336279 0.9626710562988005 0.3357126262045504 1.0 1.0 4 P55084,P40939 2 |
| Transcriptional activity of smad2 smad3 smad4 heterotrimer 0.5169911765344813 0.9623716494265724 0.3358629495175904 1.0 1.0 10 P24863,Q13547,Q13573,P09874,Q96PU5,O75376 6 |
| Signaling by ntrk3 trkc 0.6130851860896561 0.9611116700872366 0.336496022514706 1.0 1.0 4 Q07812 1 |
| Cholesterol biosynthesis 0.5328015600902771 0.9516049522812572 0.3412973690286978 1.0 1.0 15 P37268,Q16850,Q14534,Q15392,Q15738 5 |
| Signaling by notch3 0.5806591898524398 0.9510554245004198 0.3415762411727188 1.0 1.0 5 P67809 1 |
| Negative regulators of ddx58 ifih1 signaling 0.5420360380038765 0.9238347369865286 0.3555723663746513 1.0 1.0 6 Q7Z434 1 |
| Complex i biogenesis 0.5726048327176851 0.9233903651724268 0.355803810898043 1.0 1.0 28 O95168,Q9H845,P51970,O75251,Q9P032,Q9NPL8,O95182,O43676,O75306,O75489,P03886,P03905 12 |
| Acyl chain remodeling of cl 0.9138149556400508 0.9130525082159588 0.361214926244227 1.0 1.0 2 P40939 1 |
| Rhog gtpase cycle 0.5999750171805189 0.9080731772727848 0.3638395607718692 1.0 1.0 37 Q14739,Q86XL3,O95202,Q6IAA8,P84095,P42167,O15173,Q13190,Q96JJ3,O75489,O15498,P50402 12 |
| Ethanol oxidation 0.6613492355776446 0.8914763452569675 0.372673676259672 1.0 1.0 3 P05091 1 |
| Initiation of nuclear envelope ne reformation 0.524565784447029 0.8724696476300492 0.3829522195253718 1.0 1.0 17 P50402,Q14739,Q86XL3,P42167 4 |
| Platelet homeostasis 0.5100743532096639 0.8701640472114187 0.3842107606311198 1.0 1.0 13 P30626,Q16539,P23634,P16615,Q13586,P20020 6 |
| Pre notch processing in golgi 0.6553213600290886 0.8682245891154409 0.3852713956782021 1.0 1.0 3 P16615 1 |
| Degradation of cysteine and homocysteine 0.5613689378522074 0.8669150977121196 0.3859885306099015 1.0 1.0 5 Q9UBX3 1 |
| Neurexins and neuroligins 0.4892024956977522 0.8350257477623765 0.4037032115070853 1.0 1.0 9 Q9Y2J2,Q14168 2 |
| Aflatoxin activation and detoxification 0.580266940793118 0.8238101481386215 0.4100474404914611 1.0 1.0 4 O14880,Q9UJ14 2 |
| O linked glycosylation 0.5505452304085623 0.8201135769835224 0.4121513630471407 1.0 1.0 5 Q8N4A0,Q10472 2 |
| Fatty acyl coa biosynthesis 0.5124174358377932 0.8100021917142268 0.4179389160833215 1.0 1.0 17 P50897,Q9P035,Q9UKU0,O60488,O00767,Q53GQ0,P53007 7 |
| Golgi cisternae pericentriolar stack reorganization 0.4894103125445607 0.7992756880981744 0.4241305728167956 1.0 1.0 11 Q9H8Y8,Q9H0U4,P62820 3 |
| Abc transporters in lipid homeostasis 0.8719898605830168 0.7750093926777575 0.4383341094479827 1.0 1.0 2 P28288 1 |
| Carnitine metabolism 0.5377665842777137 0.7653408183822042 0.4440686238764817 1.0 1.0 5 P50416,P23786 2 |
| Linoleic acid la metabolism 0.8602661596958137 0.7372763827995401 0.4609542913672628 1.0 1.0 2 O95864 1 |
| Fgfr1 mutant receptor activation 0.4730692099902256 0.7326650903244669 0.4637627208642239 1.0 1.0 10 O94905,O15164,Q92614 3 |
| Ire1alpha activates chaperones 0.5184319003569774 0.7026645559815043 0.482264821147403 1.0 1.0 25 P49748,P43307,O14773,O95070,Q9Y5M8 5 |
| Thromboxane signalling through tp receptor 0.6113466748714605 0.7019820762971315 0.4826903413291084 1.0 1.0 3 P29992 1 |
| Reactions specific to the complex n glycan synthesis pathway 0.8475918884664084 0.6970474564124316 0.4857730952282284 1.0 1.0 2 P04066 1 |
| N glycan antennae elongation in the medial trans golgi 0.8475918884664084 0.6970474564124316 0.4857730952282284 1.0 1.0 2 P04066 1 |
| Suppression of phagosomal maturation 0.5468605592293303 0.6874833813484797 0.4917781696911745 1.0 1.0 4 P51149 1 |
| Regulation of pten localization 0.844423320659061 0.6870882533582128 0.4920271160594873 1.0 1.0 2 P46934 1 |
| Bile acid and bile salt metabolism 0.4885643195775954 0.6696106564672933 0.5031060190464496 1.0 1.0 7 P51659,O14975 2 |
| Synthesis of bile acids and bile salts 0.4885643195775954 0.6696106564672933 0.5031060190464496 1.0 1.0 7 P51659,O14975 2 |
| Signaling by notch1 0.4565933133971394 0.6656687123612182 0.5056228761548662 1.0 1.0 9 Q13573,P24863,O75376,Q96J02 4 |
| Mitochondrial fatty acid beta oxidation 0.4747945218174798 0.6535191589308166 0.5134216420855799 1.0 1.0 15 P49748,P40939,P42126,P55084,P22033 5 |
| Bmal1 clock npas2 activates circadian gene expression 0.5980982567353487 0.6533896090063682 0.5135051359922191 1.0 1.0 3 P43490,Q15648 2 |
| Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.4568951501411539 0.6495700896621823 0.5159699587195361 1.0 1.0 10 P09601,Q16539 2 |
| Bicarbonate transporters 0.8149556400506937 0.5965628072877619 0.5507993090484724 1.0 1.0 2 P04920 1 |
| Glycosaminoglycan metabolism 0.4556751516101573 0.5916833624248591 0.5540626396844193 1.0 1.0 13 Q96L58,Q8NCH0,P54802 3 |
| Clec7a dectin 1 induces nfat activation 0.8127376425855495 0.5899148456257265 0.5552477406815111 1.0 1.0 2 Q08209 1 |
| Organic anion transporters 0.8067173637515792 0.5719973288846768 0.5673237842670136 1.0 1.0 2 Q9UBX3 1 |
| Signaling by cytosolic fgfr1 fusion mutants 0.4328296361495098 0.5623819887204854 0.5738557879356572 1.0 1.0 8 O15164,Q92614 2 |
| Ksrp khsrp binds and destabilizes mrna 0.4565011382260615 0.5622766137402254 0.5739275694336352 1.0 1.0 15 Q13868,Q92945,Q16539,Q5RKV6 4 |
| Translation of sars cov 1 structural proteins 0.4861700801914889 0.5518881958918355 0.5810249562372465 1.0 1.0 5 Q10472 1 |
| Fceri mediated ca 2 mobilization 0.4848664652395939 0.546704860952335 0.5845815141099302 1.0 1.0 5 Q08209 1 |
| Acyl chain remodelling of ps 0.7965779467680556 0.5422563447963127 0.5876419247292497 1.0 1.0 2 Q6P1A2 1 |
| Ptk6 regulates proteins involved in rna processing 0.7937262357414423 0.5339941430170075 0.5933455862967612 1.0 1.0 2 Q07666 1 |
| Mitochondrial biogenesis 0.5219784193419921 0.5305567068305765 0.5957260031705363 1.0 1.0 37 Q16539,Q5XKP0,Q13505,Q6UXV4,P56134,P24539,Q9Y512,Q9NX63,Q9BUR5,P48735,P36542,O75964 12 |
| Rab gefs exchange gtp for gdp on rabs 0.4742183748573687 0.5192545203006552 0.6035832639551137 1.0 1.0 23 Q9UL25,P61020,P51151,Q9H0U4,P62820,P61106,Q13636,P51148,P51149,Q14964,Q6IQ22,Q9NP72,P61026,P51153 14 |
| Respiratory electron transport 0.5620824985864419 0.4987937906037845 0.6179246624250307 1.0 1.0 52 O95168,Q9H845,P00403,O95182,O43676,O75306,O75489,P03886,P13073,Q12931,Q9UDW1,Q9P032,P10606,P03905,Q16134,O96000,P15954,O75251,O14949,Q9NPL8,O14548,P51970,P22695 23 |
| Activation of ppargc1a pgc 1alpha by phosphorylation 0.5506507504200736 0.4874229132878815 0.6259586590187851 1.0 1.0 3 Q16539 1 |
| Effects of pip2 hydrolysis 0.4679427866449949 0.4806202286537159 0.6307864357795983 1.0 1.0 5 Q8NCG7 1 |
| Aspartate and asparagine metabolism 0.4671766412580179 0.4776850307729589 0.6328744001827271 1.0 1.0 5 O75746 1 |
| Atf4 activates genes in response to endoplasmic reticulum stress 0.4341915195290801 0.4699415908538975 0.6383967485903168 1.0 1.0 14 Q13868,Q92945,Q5RKV6 3 |
| Thrombin signalling through proteinase activated receptors pars 0.4401105186026053 0.469698815685214 0.638570214122353 1.0 1.0 6 P29992,P12931 2 |
| Stat3 nuclear events downstream of alk signaling 0.486683576410906 0.4570522178400296 0.6476335134087654 1.0 1.0 4 Q96ST3,Q13547,Q92769 3 |
| Glutamate and glutamine metabolism 0.410793650793639 0.4535691996938867 0.6501389262483963 1.0 1.0 8 P00367,P32322,Q96C36,O94925,P04181,P54886,P00505 7 |
| Prevention of phagosomal lysosomal fusion 0.7582382762991088 0.4353093202346148 0.6633379206476957 1.0 1.0 2 P51149 1 |
| Metabolism of fat soluble vitamins 0.4517481140938639 0.4197346504918624 0.6746793090373442 1.0 1.0 5 Q6NUM9,Q8TC12,Q8N0U8 3 |
| Visual phototransduction 0.4034303408777727 0.4181877135435596 0.6758098781466435 1.0 1.0 8 O75911,Q6NUM9,Q8TC12 3 |
| Glycosphingolipid metabolism 0.4264653862601458 0.4024186233220306 0.6873759664504275 1.0 1.0 16 O43681,Q9NZJ7,Q9NXE4,Q16880 4 |
| Beta oxidation of butanoyl coa to acetyl coa 0.5197586144189056 0.3881789603829879 0.697883601990503 1.0 1.0 3 P40939 1 |
| Gamma carboxylation hypusine formation and arylsulfatase activation 0.4036131617366597 0.3877906082545658 0.6981709962562035 1.0 1.0 10 O43681,O60725 2 |
| Signaling by flt3 fusion proteins 0.4414843006660456 0.3825074830985709 0.7020849794356567 1.0 1.0 5 Q14789,Q9UBW7,Q92614,Q01082 4 |
| Diseases associated with glycosaminoglycan metabolism 0.4651875808160986 0.3817081363251361 0.702677864343995 1.0 1.0 4 Q8NCH0 1 |
| Chondroitin sulfate dermatan sulfate metabolism 0.4651875808160986 0.3817081363251361 0.702677864343995 1.0 1.0 4 Q8NCH0 1 |
| Non integrin membrane ecm interactions 0.4404021801191765 0.378649133804616 0.704948430721023 1.0 1.0 5 P12814,O14936 2 |
| Cyclin a b1 b2 associated events during g2 m transition 0.4008848194623365 0.3750917713122872 0.7075922165691522 1.0 1.0 10 P30154,P24941,Q99640 3 |
| Protein localization 0.6009364557472516 0.3705808598311293 0.7109497402201117 1.0 1.0 75 O60830,O75874,P34913,P28288,O43615,A8MXV4,P09601,Q10713,P40855,Q8TB36,P12235,Q3ZCQ8,Q13505,Q9NS69,O43681,Q9NX63,P50402,O14975,O43808,O15254,O14925,P51648,O00116,Q5JRX3,O75381,O15228,P21796,Q13190,Q9Y512 29 |
| Diseases of carbohydrate metabolism 0.3932604301839133 0.3702830728425045 0.7111715848232634 1.0 1.0 8 P54802 1 |
| Signaling by fgfr1 in disease 0.4014197929595633 0.3624025791367357 0.7170512124368702 1.0 1.0 11 O94905,O15164,Q92614 3 |
| Respiratory electron transport atp synthesis by chemiosmotic coupling and heat production by uncoupling proteins 0.5563485284416035 0.3434132360662381 0.7312876033824831 1.0 1.0 62 O95168,Q9H845,P00403,P24539,O95182,O43676,O75306,O75489,P03886,O75964,P13073,Q12931,Q9UDW1,Q9P032,P10606,P03905,Q16134,P36542,O96000,P15954,O75251,O14949,Q9NPL8,O14548,P51970,P56134,P22695 27 |
| Notch1 intracellular domain regulates transcription 0.4126755396099784 0.3394036038755452 0.7343057040486121 1.0 1.0 7 Q13573,P24863,O75376 3 |
| Class b 2 secretin family receptors 0.7129277566539869 0.322152662146354 0.7473370444033154 1.0 1.0 2 Q9Y3E5 1 |
| G protein activation 0.7129277566539867 0.3221526621463537 0.7473370444033156 1.0 1.0 2 P29992 1 |
| G0 and early g1 0.4025610995972913 0.3221349572681014 0.7473504565469691 1.0 1.0 6 P24941 1 |
| Cargo concentration in the er 0.4074913465740314 0.3165691280917759 0.7515705640261108 1.0 1.0 16 P49755,Q9Y6B6,Q13190,Q96PC5 4 |
| Antigen presentation folding assembly and peptide loading of class i mhc 0.3941741770486989 0.3149001972775151 0.7528374318131108 1.0 1.0 12 P04439,Q9Y6B6,P27824,P10321,P51572 5 |
| Iron uptake and transport 0.4163251048983928 0.3129974650146929 0.7542825880864297 1.0 1.0 19 P09601 1 |
| Rnd2 gtpase cycle 0.4130991481586674 0.312926186815647 0.7543367418033271 1.0 1.0 18 Q9Y2I1,Q07065,Q8TAA9,P51648,P38159 5 |
| Metabolism of steroids 0.4907985754197473 0.3093075855262102 0.7570875612920314 1.0 1.0 43 P37268,Q16850,P30536,O00767,P38435,Q53GQ0,Q9Y6B6,Q14534,Q15392,Q15738,O14975,Q8NBQ5 12 |
| Metabolism of cofactors 0.4046955571473384 0.3079048381647491 0.7581547442112835 1.0 1.0 7 P00374,O75874 2 |
| Pyruvate metabolism 0.4044814832051343 0.303362536932705 0.761613592452627 1.0 1.0 16 Q9P0J1,P21796,P35613,P48163,O95563 5 |
| Vegfr2 mediated cell proliferation 0.4393341221290674 0.2976188209094377 0.765994108184668 1.0 1.0 4 P12931 1 |
| Pi5p regulates tp53 acetylation 0.6951837769328196 0.2823535430946952 0.7776724335043377 1.0 1.0 2 Q8TBX8 1 |
| Diseases of mismatch repair mmr 0.483042789223448 0.2820870187813697 0.7778767867254441 1.0 1.0 3 P20585,P43246 2 |
| Signaling by notch1 pest domain mutants in cancer 0.3726430873446905 0.2771839935138304 0.7816388296167838 1.0 1.0 8 Q13573,P24863,O75376 3 |
| Gaba receptor activation 0.4311984781230206 0.2728327883730844 0.7849817539111985 1.0 1.0 4 Q9UBI6,P04899,P08754 3 |
| Gaba b receptor activation 0.4311984781230206 0.2728327883730844 0.7849817539111985 1.0 1.0 4 Q9UBI6,P04899,P08754 3 |
| Adp signalling through p2y purinoceptor 12 0.4311984781230206 0.2728327883730844 0.7849817539111985 1.0 1.0 4 Q9UBI6,P04899,P08754 3 |
| Glycerophospholipid biosynthesis 0.4557023999254345 0.2663055548447413 0.7900038953784665 1.0 1.0 35 Q6P1A2,Q8IV08,Q9BZF1,P40939,P48651,Q9UG56,Q9HCL2,Q92604,Q9Y6K0,Q8WUK0,P55084,Q7L5N7,O15228,Q53H12,Q9BVG9,O95674,Q9NQZ5 17 |
| Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.6840937896070909 0.2588808439968567 0.7957271787431068 1.0 1.0 2 P06493 1 |
| Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.3950547090229793 0.2494077093712496 0.8030454223246659 1.0 1.0 17 Q07065,O76024,P07237 3 |
| Phospholipid metabolism 0.4970205191206165 0.2366059099281201 0.8129625349189229 1.0 1.0 51 Q6P1A2,Q8IV08,P40939,P48651,Q92604,Q8NEB9,Q9Y6K0,Q8TBX8,P55084,Q7L5N7,Q10713,O15228,Q8IY17 13 |
| Interleukin 12 signaling 0.4177111867108158 0.2259167405739342 0.8212661773020731 1.0 1.0 26 P14174,P52597,Q13126,P51809,P07237,O14979 6 |
| Nef mediated downregulation of mhc class i complex cell surface expression 0.4139189660881103 0.223132124085562 0.8234326771412062 1.0 1.0 4 Q9BXS5 1 |
| E3 ubiquitin ligases ubiquitinate target proteins 0.3776056311752376 0.2167917864865262 0.8283706131830844 1.0 1.0 14 O75381,Q9BUN8 2 |
| Interleukin 12 family signaling 0.421823112592786 0.2051939741944536 0.8374205771790342 1.0 1.0 29 P14174,P52597,P22626,Q13126,P51809,P07237,O14979 7 |
| Mecp2 regulates transcription of neuronal ligands 0.4522979397781297 0.2051078207511363 0.8374878862581525 1.0 1.0 3 Q96ST3,Q13547 2 |
| Ampk inhibits chrebp transcriptional activation activity 0.6517743979721087 0.1969356938121307 0.843877860989295 1.0 1.0 2 P54646 1 |
| Rac2 gtpase cycle 0.4356808076133247 0.1872847100888409 0.8514374104648947 1.0 1.0 35 Q14739,Q86XL3,Q13505,Q6IAA8,P42167,O15173,Q9Y512,P50402 8 |
| Growth hormone receptor signaling 0.3623096446700439 0.1850316414823094 0.8532042177466037 1.0 1.0 6 P18031,P40763,P07948,P42224,P27361 5 |
| Activated ntrk2 signals through fyn 0.6441698352344659 0.1837999504217048 0.8541703950328869 1.0 1.0 2 P12931 1 |
| Energy dependent regulation of mtor by lkb1 ampk 0.3691865356459269 0.1786258909988324 0.858231463368351 1.0 1.0 7 Q9Y376,Q6IAA8,Q13131 3 |
| Fatty acid metabolism 0.5049717347376386 0.1770651915966956 0.859457182951421 1.0 1.0 59 P49748,P40939,P34913,A8MXV4,P55084,P22033,O14975,O43808,P50897,O15254,P50416,O60488,Q9UKU0,Q9P035,O00767,P42126,Q53GQ0,P51648,Q9H7Z7,P53007,P23786,O43772,O95864 23 |
| Sialic acid metabolism 0.3963221306277755 0.17692909836309 0.8595640819921035 1.0 1.0 4 P10619,P16278,Q9NR45 3 |
| Rac3 gtpase cycle 0.432748016863179 0.176212345169211 0.8601271225010705 1.0 1.0 35 Q15758,Q14739,Q9UQB8,Q9H0H5,O00161,Q6IAA8,P51149,Q8TAA9,O15173,P42167,P50402,O15498 12 |
| G2 m dna replication checkpoint 0.4382696414274503 0.173988315777651 0.8618746448369139 1.0 1.0 3 Q99640 1 |
| Signal regulatory protein family interactions 0.3933640038149556 0.1696220485112922 0.8653073816159349 1.0 1.0 4 Q08722 1 |
| Synthesis of pips at the plasma membrane 0.346036779580483 0.1668634581754307 0.8674774861279355 1.0 1.0 8 Q9BTU6,Q8TBX8,P61106 3 |
| Activated ntrk2 signals through cdk5 0.6305449936628557 0.1616617782649781 0.871572205066284 1.0 1.0 2 P63000 1 |
| Adrenaline noradrenaline inhibits insulin secretion 0.4310618066561039 0.1590227082875757 0.8736509828581347 1.0 1.0 3 Q9UBI6,P04899 2 |
| Adenylate cyclase inhibitory pathway 0.4310618066560893 0.1590227082875462 0.873650982858158 1.0 1.0 3 P04899,P08754 2 |
| Mrna decay by 3 to 5 exoribonuclease 0.363645282882103 0.1380076168141788 0.8902343978059635 1.0 1.0 16 Q9GZS3,Q13868,Q5RKV6 3 |
| Plasma lipoprotein assembly remodeling and clearance 0.3594647761146595 0.1341334039410349 0.893297085783175 1.0 1.0 15 Q8WTV0,Q6PIU2,Q9Y6B6,P35610,P07237 5 |
| G beta gamma signalling through pi3kgamma 0.6108998732572781 0.1329054889184255 0.8942681258887848 1.0 1.0 2 Q9UBI6 1 |
| Miro gtpase cycle 0.4148969889064892 0.1280407231870232 0.8981167458136521 1.0 1.0 3 Q8IXI2,Q8IXI1 2 |
| Tgf beta receptor signaling in emt epithelial to mesenchymal transition 0.6064638783269866 0.1269268484319068 0.8989982965215675 1.0 1.0 2 P61586 1 |
| Ngf stimulated transcription 0.4044374009508609 0.1099146129084107 0.9124770933390114 1.0 1.0 3 P50570,Q00535 2 |
| Loss of function of mecp2 in rett syndrome 0.3469711385981565 0.106638515517657 0.9150757618230504 1.0 1.0 5 P51608,O75376,Q96ST3,Q13547 4 |
| Sumoylation of transcription factors 0.346019663812245 0.1045939472015387 0.9166980177950296 1.0 1.0 5 Q13330,P04637,P42771,Q12888 4 |
| Adora2b mediated anti inflammatory cytokines production 0.3324865036519587 0.1045456227820779 0.9167363648694686 1.0 1.0 9 P31323,P63096,P04899,P08754,Q9UBI6,P13861,P17612,Q9Y3E5 8 |
| Signaling by erbb4 0.3324746647831215 0.1045035929779985 0.9167697171095184 1.0 1.0 9 P46934,Q96J02 2 |
| Rhobtb3 atpase cycle 0.3633563910302845 0.1033500299161623 0.9176851700388646 1.0 1.0 4 Q15345 1 |
| Smad2 smad3 smad4 heterotrimer regulates transcription 0.3620798985415286 0.1008545423183626 0.9196659290144432 1.0 1.0 4 P24863,P27361,Q13547 3 |
| Regulation of mecp2 expression and activity 0.3328325770137426 0.0947574060432857 0.92450751963217 1.0 1.0 10 Q14739,O75376,Q9HCE1 3 |
| Sars cov 2 infection 0.3785661459988778 0.0921482337664868 0.9265802664382664 1.0 1.0 25 Q16706,P61803,Q8NEB9,P46977,P27824,Q10472 6 |
| Ecm proteoglycans 0.3892234548335807 0.0862424701517547 0.9312736701539304 1.0 1.0 3 P05556,P05067 2 |
| G alpha s signalling events 0.33786824570786 0.0823096312255725 0.9344004957997708 1.0 1.0 7 Q9Y3E5,P12931 2 |
| G alpha z signalling events 0.3346019663812258 0.08131732531416 0.9351895960101824 1.0 1.0 5 Q9UBI6,P63096,P04899,P08754 4 |
| The phototransduction cascade 0.3832012678288448 0.0777450838523216 0.9380308308828584 1.0 1.0 3 P49354,P30419 2 |
| Regulation of cholesterol biosynthesis by srebp srebf 0.3705451547716998 0.0756380582020546 0.9397070571102752 1.0 1.0 24 Q16850,Q9Y6B6,Q14534,O00767 4 |
| Regulation of lipid metabolism by pparalpha 0.3640790676193305 0.074582902128279 0.940546578353916 1.0 1.0 22 P24863,P50416,P37268,P23786,P11310,P33121,P48163 7 |
| Nr1h3 nr1h2 regulate gene expression linked to cholesterol transport and efflux 0.3475471159128847 0.0743285995332797 0.9407489208308436 1.0 1.0 4 Q9HCE1 1 |
| Butyrate response factor 1 brf1 binds and destabilizes mrna 0.332047872681207 0.0709153985310273 0.9434650879752406 1.0 1.0 12 Q13868,Q5RKV6 2 |
| Slc transporter disorders 0.3872318424560456 0.0702460330442069 0.9439978357207264 1.0 1.0 30 Q8N1F7,Q9BTX1,Q12769,Q8TEM1,Q9NRG9,Q8NFH5,P08195,P35613,Q7Z3B4,P11166,P57740 11 |
| Peptide hormone metabolism 0.3469499277621105 0.0689646358479581 0.9450177689566348 1.0 1.0 17 P67812 1 |
| G protein mediated events 0.3329093799682088 0.0635491643093715 0.9493292108710624 1.0 1.0 13 P29992,P31323,P63096,P04899,P08754,P13861,P17612,O43865,P52292,Q05655,Q13555,P28482 12 |
| Signaling by ptk6 0.3296473612020944 0.06302697949185 0.949745020497928 1.0 1.0 12 Q96JJ3,P24941,Q07666 3 |
| Platelet adhesion to exposed collagen 0.5361216730037901 0.0561044277408585 0.9552586166694456 1.0 1.0 2 P05556 1 |
| Suppression of apoptosis 0.3619651347068134 0.0516181532410478 0.9588329544272876 1.0 1.0 3 P23246,P27361 2 |
| P75ntr negatively regulates cell cycle via sc1 0.5164765525982127 0.0435771249371495 0.9652414860281208 1.0 1.0 2 Q13547 1 |
| Apex1 independent resolution of ap sites via the single nucleotide replacement pathway 0.3540412044374045 0.0433454654759868 0.9654261490492212 1.0 1.0 3 P18887,P49916 2 |
| Beta oxidation of very long chain fatty acids 0.3118738472128406 0.0418983887273418 0.9665797008810352 1.0 1.0 5 P51659 1 |
| Ncam signaling for neurite out growth 0.3055203045685281 0.0407320616923247 0.967509501263354 1.0 1.0 6 P62993,Q01082,P12931,P27361,P28482 5 |
| Perk regulates gene expression 0.3329889278457116 0.0346395518124905 0.9723671626264092 1.0 1.0 16 Q13868,Q92945,Q5RKV6 3 |
| Camk iv mediated phosphorylation of creb 0.4949302915082245 0.0328318170248431 0.9738087055664676 1.0 1.0 2 P52292 1 |
| Creb1 phosphorylation through the activation of camkii camkk camkiv cascasde 0.4949302915082245 0.0328318170248431 0.9738087055664676 1.0 1.0 2 P52292 1 |
| Caspase mediated cleavage of cytoskeletal proteins 0.3054234062797318 0.0323642872760862 0.9741815421844406 1.0 1.0 5 Q15149,Q9UJU6,P35611,P08670 4 |
| Repression of wnt target genes 0.3413629160063389 0.0316812412428104 0.9747262546967664 1.0 1.0 3 Q13547,P56545 2 |
| Transcriptional regulation of pluripotent stem cells 0.4863751584283761 0.0293357466800106 0.9765968174345392 1.0 1.0 2 Q99626 1 |
| Anti inflammatory response favouring leishmania parasite infection 0.3272982364972894 0.0267906599633188 0.9786267028152618 1.0 1.0 15 Q9Y3E5,Q16539,P12931 3 |
| Activation of ampk downstream of nmdars 0.3157727705490267 0.0259906836466926 0.9792647693152964 1.0 1.0 7 P54646,Q13885,P68371,P04350,Q13131,Q9BUF5 6 |
| Fcgr3a mediated il10 synthesis 0.3031746031745968 0.0193484815494033 0.9845631084714976 1.0 1.0 8 P31323,P13861,P17612,O43865,P07948,P12931,P10644 7 |
| Loss of mecp2 binding ability to the ncor smrt complex 0.4521546261089832 0.0189902971363212 0.984848845778966 1.0 1.0 2 O75376 1 |
| Gene and protein expression by jak stat signaling after interleukin 12 stimulation 0.3509683260763031 0.0153483005733164 0.9877543087268 1.0 1.0 24 P52597,O14979,P14174,Q13126 4 |
| Dag and ip3 signaling 0.3032708796443403 0.0106651775228503 0.9914905808353502 1.0 1.0 9 P31323,P13861,P17612,O43865,P52292,Q05655,Q13555,P10644 8 |
| Laminin interactions 0.3891001267426948 0.0104292422212 0.991678819498981 1.0 1.0 2 P05556 1 |
| Tp53 regulates transcription of death receptors and ligands 0.3856147021546185 0.0102049439937312 0.9918577740668876 1.0 1.0 2 P04637 1 |
| Response to elevated platelet cytosolic ca2 0.3664411594946493 0.007505411179178 0.994011604519957 1.0 1.0 30 Q6UXV4,Q9NZJ7,Q8NBM8,Q96JJ7 4 |
| Dna damage recognition in gg ner 0.3227769957976555 0.0048660578165519 0.9961174629183264 1.0 1.0 16 Q99627 1 |
| Cargo trafficking to the periciliary membrane 0.3376280774108808 0.0035575326381172 0.9971615056208444 1.0 1.0 21 Q10713 1 |
| Regulation of tp53 expression and degradation 0.3030533650668315 0.001355840260933 0.9989181963203336 1.0 1.0 10 P30154,Q93009,P24941 3 |
|
|
