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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{"0": "Serine/threonine-protein kinase, active site [IPR008271]"}

interpro_active_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:68522436e30e68e808b5ea424d6e29437945efc5e5ccfc01af8058767547d8e9
+size 83885

interpro_active_site/df_merge.tsv

@@ -0,0 +1 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3216,
+    "annotations_size": 53,
+    "title": "Average number of proteins per term",
+    "value": 3.207547169811321
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C030/C030_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,14 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Peptidase S9, serine active site [IPR002471]	0.8615432482887393	2.4040716803602704	0.016213593762562	0.5795219636601721	0.0409200223531327	2	P13798	1
+Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]	0.8556316116988198	2.3781115705981484	0.0174015598111472	0.6056047003745458	0.0419219395450364	2	P18669	1
+L-lactate dehydrogenase, active site [IPR018177]	0.7629122588674613	1.9617833762132308	0.0497877099026005	0.9332434175339532	0.0855597224030302	2	P00338	1
+Peptidase family C14A, cysteine active site [IPR033139]	0.7820672478206716	1.7637802305241002	0.0777689871763769	0.986306789074918	0.1177644662956565	4	P55210,P42575,P55212	3
+Peptidase family C14A, His active site [IPR016129]	0.7820672478206716	1.7637802305241002	0.0777689871763769	0.986306789074918	0.1177644662956565	4	P55210,P42575,P55212	3
+Ubiquitin-activating enzyme E1, Cys active site [IPR033127]	0.7152194211017842	1.336126652324647	0.1815078798910265	0.9999754659841404	0.2346321374201075	3	Q8TBC4,Q9UBT2	2
+Nucleoside diphosphate kinase, active site [IPR023005]	0.6513962873854245	1.1975173792211096	0.231104957765182	0.9999991067886912	0.291632446703682	4	P15531	1
+Serine/threonine-protein kinase, active site [IPR008271]	0.2900840343420464	1.148096739489062	0.2509286300437501	0.9999997762672752	0.3022549407345171	56	Q96GX5,P06493,P28482,Q86UE8,P49760,Q99986,P78362,Q96SB4,P19784,Q7KZI7,Q8TD19,Q00536,Q02750,Q13546,Q96KB5,O14757	16
+Protein-tyrosine phosphatase, active site [IPR016130]	0.4072322870730697	0.7353774838256574	0.4621096307434205	0.9999999999999948	0.5442624539866953	10	Q06124,Q13614	2
+Ubiquitin-conjugating enzyme, active site [IPR023313]	0.4781593820106061	0.5698723981224537	0.5687642470380334	1.0	0.6553153281090385	5	P61088,P61081	2
+Tyrosine-protein kinase, active site [IPR008266]	0.3957390620122394	0.4716179205578639	0.6371995330583564	1.0	0.7185441542998487	8	P07948,P12931	2
+ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]	0.4247044181705056	0.4264151650961025	0.6698053529139296	1.0	0.739576743842464	2	P53396	1
+Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]	0.3243985484352302	0.0693115882551622	0.9447416018286576	1.0	0.962909709556132	3	P00390	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "DNA topoisomerase, type IA, active site [IPR023406]", "DNA/RNA non-specific endonuclease, active site [IPR018524]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ADSS", "AMPD2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CAPN5", "CASP2", "CASP3", "CASP6", "CASP7", "CDK1", "CDK11B", "CDK12", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CHEK1", "CHUK", "CKB", "CKMT1A*", "CLK2", "CLPP", "CPVL", "CS", "CSK", "CSNK2A2", "CTSA", "CTSB", "CTSC", "DLD", "DNMT1", "DNMT3B", "DUSP11", "DUSP3", "EIF2AK2", "ENDOG", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLUD1", "GRK2", "GSK3B", "GSR", "HADHB", "HMGCL", "HMGCS1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAP2K2", "MAP4K4", "MAPK1", "MARK2", "MARK3", "MASTL", "MDH1", "MDH2", "MKNK1", "MTMR14", "MTMR2", "MTMR6", "NEK9", "NME1", "NME2", "NME3", "NME6", "OXCT1", "OXSM", "PAK2", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCB", "PRKCD", "PRPF4B", "PTK2", "PTK7", "PTPMT1", "PTPN1", "PTPN11", "PTPRA", "PTPRF", "RIPK1", "ROCK1", "ROCK2", "RPS6KA1", "RRM2", "SCP2", "SCPEP1", "SLK", "SND1", "SRC", "SRPK1", "SRPK2", "STK10", "STK38", "SUCLG1", "TALDO1", "TIGAR", "TLK2", "TOP1", "TOP3B", "TP53RK", "TPI1", "TPP2", "TTK", "TXNRD1", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2N", "UMPS", "UNG", "VRK1", "YES1"], "leading_proteins": ["ACLY", "APEH", "CASP2", "CASP6", "CASP7", "CDK1", "CDK16", "CHEK1", "CLK2", "CSNK2A2", "GSR", "LDHA", "LYN", "MAP2K1", "MAPK1", "MARK2", "MASTL", "MTMR2", "NEK9", "NME1", "PBK", "PGAM1", "PTPN11", "RIPK1", "SRC", "SRPK1", "SRPK2", "TLK2", "UBA2", "UBA3", "UBE2M", "UBE2N", "VRK1"]}

interpro_binding_site/advanced/idx2term.json

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+{}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Protein kinase, ATP binding site [IPR017441]", "1": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:70ef05dd116f6869c6a0a3d62b789928ac455a9344a623ecb1169d6634aeda7d
+size 78464

interpro_binding_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500
+Beta tubulin, autoregulation binding site [IPR013838]	4	5	2.295043063655607	0.0217306564990087	3.5533980582524274	5.54126213592233	0.5823511994709325	0.3808337519133083	1.5578062452886454	0.9632803779920796	1.1906256051626651	0.3058955364405814	1.0	1.0	0.0189506401306209	2.915330495677531e-05

interpro_binding_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 3216,
+    "annotations_size": 32,
+    "title": "Average number of proteins per term",
+    "value": 4.78125
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C030/C030_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,8 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]	0.8839452395768546	2.5017953845296947	0.0123565316471336	0.3282521736225082	0.0359462738825707	2	Q9Y617	1
+Beta tubulin, autoregulation binding site [IPR013838]	0.8657739022111425	2.295043063655607	0.0217306564990087	0.5049258968807768	0.0496700719977342	5	Q9BUF5,P68371,Q13885,P04350	4
+PPM-type phosphatase, divalent cation binding [IPR000222]	0.894491129785247	2.0703084049453944	0.0384234730076613	0.7145807216449874	0.0768469460153227	3	P49593,Q9H0C8	2
+Inositol monophosphatase, metal-binding site [IPR020583]	0.7790914747977689	2.0356343140123547	0.0417870894601177	0.7448564594839922	0.078658050748457	2	O95861	1
+Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]	0.7389545737398846	1.8515636790324972	0.0640885026825319	0.8799082873397248	0.0976586707543344	2	Q9UQ80	1
+Protein kinase, ATP binding site [IPR017441]	0.2750991942017082	0.9870847277119924	0.323601104070959	0.9999963145333874	0.3835272344544699	58	P06493,P28482,O95747,Q86UE8,P49760,Q99986,P78362,P24941,P07948,Q00535,Q96SB4,P19784,Q7KZI7,P12931,P41240,Q00536,Q02750,O14757	18
+EF-Hand 1, calcium-binding site [IPR018247]	0.2822793198400467	0.6666980013281213	0.5049650557127392	0.9999999998308208	0.5386293927602551	31	P42566,Q9UBV8,Q9Y680,P13797,P17655	5

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "APEX1", "APOBEC3C", "ARAF", "ARG2", "AURKA", "BPNT1", "BUB1", "CALM3", "CAMK2D", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK12", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK9", "CEP97", "CHEK1", "CHUK", "CLK2", "COX2", "COX5B", "CSK", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "EHD1", "EHD4", "EIF2AK2", "EPHA7", "EPS15", "FKBP10", "FKBP7", "GCAT", "GOT1", "GOT2", "GPD2", "GRK2", "GSK3B", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IMPA1", "IQGAP1", "IQGAP3", "LETM1", "LYN", "MACF1", "MAP2K1", "MAP2K2", "MAP4K4", "MAPK1", "MAPK14", "MARK2", "MARK3", "MCCC1", "METAP2", "MICU1", "MKNK1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "NFS1", "NRDC", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PC", "PCCA", "PDCD6", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1F", "PPM1G", "PRKAA1", "PRKAA2", "PRKACA", "PRKCB", "PRKCD", "PRKCSH", "PSAT1", "PTK2", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "S100A11", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRC", "SRI", "SRPK1", "SRPK2", "STK10", "STK38", "TBK1", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "UBE3C", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["BPNT1", "CAPN2", "CDK1", "CDK16", "CDK2", "CDK5", "CHEK1", "CLK2", "CSK", "CSNK2A2", "EPS15", "FKBP7", "ILKAP", "LYN", "MAP2K1", "MAPK1", "MARK2", "OXSR1", "PA2G4", "PEF1", "PLS3", "PPM1F", "PSAT1", "SRC", "SRPK1", "SRPK2", "TLK2", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "VRK1"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Chaperonin TCP-1, conserved site [IPR002194]", "1": "Proteasome beta-type subunit, conserved site [IPR016050]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Chaperonin TCP-1, conserved site [IPR002194]", "1": "Proteasome beta-type subunit, conserved site [IPR016050]", "2": "Ubiquitin specific protease, conserved site [IPR018200]", "3": "ATPase, AAA-type, conserved site [IPR003960]", "4": "Heat shock protein 70, conserved site [IPR018181]"}

interpro_conserved_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:f780cfcf03a424895783838270e7511d49c4fba7c62e8b6ea616b9b5f5cca755
+size 143693

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_50	pval_100	pval_250	pval_500
+Tubulin, conserved site [IPR017975]	4	5	2.295043063655607	0.0217306564990087	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.0	1.0	0.0698282842903305	0.0013736729067174
+Chaperonin TCP-1, conserved site [IPR002194]	7	8	2.0744204094608363	0.03804028346521	5.461165048543689	8.0	-0.4692686565402914	0.4573595711033881	2.1043059418798453	0.0	0.968912135079772	0.3098429291835972	1.0	1.0	1.0	0.0078003581692789
+Proteasome beta-type subunit, conserved site [IPR016050]	6	8	1.9860234199401217	0.0470307234862799	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	1.0	1.0	0.0015031185668187	0.0009328306623149

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3216,
+    "annotations_size": 278,
+    "title": "Average number of proteins per term",
+    "value": 2.6906474820143886
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C030/C030_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,49 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Polyamine biosynthesis domain, conserved site [IPR030373]	0.9259489732420684	2.6822460386914373	0.0073129653475578	0.8700329670181379	0.018151824701974	2	P52788	1
+F-actin capping protein, alpha subunit, conserved site [IPR017865]	0.9019912881145042	2.57976637832876	0.0098867174971863	0.9368463444399826	0.0227149377208084	2	P47755	1
+Fructose-bisphosphate aldolase class-I active site [IPR029768]	0.880833851897951	2.4882843765757134	0.0128361047906013	0.97244406774851	0.0278784150920873	2	P04075	1
+DNA methylase, N-6 adenine-specific, conserved site [IPR002052]	0.86963285625389	2.4394798190381173	0.0147084241842028	0.9837442896371016	0.0309768327515786	2	Q9Y5N5	1
+Macrophage migration inhibitory factor, conserved site [IPR019829]	0.847542003733667	2.342471253196077	0.0191565096548695	0.9953791643587234	0.0385906498844474	2	P14174	1
+Tubulin, conserved site [IPR017975]	0.8657739022111421	2.295043063655607	0.0217306564990087	0.9977743983023492	0.0424695347748719	5	Q9BUF5,P68371,Q13885,P04350	4
+Chaperonin TCP-1, conserved site [IPR002194]	0.7060473815461386	2.0744204094608363	0.03804028346521	0.999979221498415	0.0673579541613273	8	P40227,P17987,Q99832,P78371,P50990,P49368,P48643	7
+Inositol monophosphatase, conserved site [IPR020550]	0.7790914747977689	2.0356343140123547	0.0417870894601177	0.99999297832023	0.0708342126214191	2	O95861	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.6887538980596281	1.9860234199401217	0.0470307234862799	0.99999847266603	0.0778246495784869	8	P28070,P28072,P49721,P25789,P28074,P49720	6
+Purine phosphorylase, family 2, conserved site [IPR018099]	0.7626011200995761	1.9603584532388207	0.049953908319984	0.999999349840608	0.082172701260092	2	Q13126	1
+Ubiquitin interacting motif [IPR003903]	0.853096794273248	1.90409074088494	0.0568983673822329	0.999999915421092	0.090745527958233	3	P42566,P55036	2
+GTP1/OBG, conserved site [IPR006074]	0.747666459240819	1.8917590263638535	0.0585230948073611	0.9999999476292786	0.0924398883889	2	P55039	1
+Aldo/keto reductase, conserved site [IPR018170]	0.7392657125077788	1.8530014347474304	0.0638821530104718	0.9999999892876198	0.0985239073055142	2	P15121	1
+Ubiquitin-activating enzyme E1, conserved site [IPR018074]	0.7149968886123192	1.7403886255384302	0.0817908014357988	0.9999999999501372	0.1209459723359153	2	Q9UBT2	1
+Ubiquitin specific protease, conserved site [IPR018200]	0.5001817332573159	1.730447877779726	0.0835502860286947	0.9999999999707448	0.1228940715131065	15	O94782,P54578,Q8NB14,Q9UPT9,Q96RU2,P45974,Q86UV5	7
+tRNA-dihydrouridine synthase, conserved site [IPR018517]	0.7927170868347231	1.6575637785961452	0.0974055457279852	0.9999999999995764	0.1417735168187429	3	Q96G46,Q6P1R4	2
+S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]	0.6894835096453065	1.6210711769754254	0.1050023746562753	0.9999999999999596	0.1512469438054122	2	P23526	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.7790227201991771	1.601081666358836	0.1093588322995553	0.9999999999999896	0.155906437842443	3	P09429,O15347	2
+Fork head domain conserved site 2 [IPR030456]	0.6729931549471191	1.5435269160085168	0.1227029820236287	1.0	0.172017639653778	2	P85037	1
+Fork head domain conserved site1 [IPR018122]	0.6729931549471191	1.5435269160085168	0.1227029820236287	1.0	0.172017639653778	2	P85037	1
+Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]	0.6714374611076537	1.536196882649976	0.1244901003505221	1.0	0.1730412394872257	2	P60891	1
+Phosphorylase pyridoxal-phosphate attachment site [IPR035090]	0.6705040448039822	1.5317977682852792	0.1255723469671501	1.0	0.173677176402327	2	P11216	1
+Alpha-D-phosphohexomutase, conserved site [IPR016066]	0.7491441020852752	1.4772935701680798	0.1395969608152718	1.0	0.1906180308293518	3	P36871,O95394	2
+Histidine triad, conserved site [IPR019808]	0.748277843785694	1.4736952742281542	0.1405636558273997	1.0	0.1906180308293518	3	P49773	1
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.7356483481235299	1.4211887230495002	0.1552619021786281	1.0	0.2065206162950173	3	P10644	1
+Tr-type G domain, conserved site [IPR031157]	0.6099481252801191	1.2951189674628156	0.1952791926856905	1.0	0.2456453193059816	6	Q05639	1
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]	0.6706194530419972	1.281267728305412	0.2000996440444624	1.0	0.2494840420689738	4	O43175,Q9UBQ7	2
+IMP dehydrogenase / GMP reductase, conserved site [IPR015875]	0.698723934018054	1.2674017219337377	0.2050116844162812	1.0	0.2533033256343386	3	P12268,P20839	2
+Phosphofructokinase, conserved site [IPR015912]	0.6657329598506003	1.1301901097412432	0.2583961263328802	1.0	0.3150619435111434	3	P08237,P17858	2
+Clathrin adaptor complex, small chain [IPR000804]	0.6647992530345465	1.1263170740785284	0.2600313332360962	1.0	0.3156712255005883	3	P61923,P53680	2
+Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]	0.5830740510267638	1.1184309114299398	0.2633829984154088	1.0	0.3183498850412332	2	Q08257	1
+D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]	0.6514161220043619	1.0709029598866149	0.2842130648611216	1.0	0.3405656553077233	3	Q13363,O43175	2
+Ribosomal protein L30, conserved site [IPR018038]	0.5625388923459933	1.0220476518464816	0.3067583475092061	1.0	0.364439404305809	2	P18124	1
+Actin/actin-like conserved site [IPR020902]	0.6346407577099622	1.0017788790630728	0.3164504002458179	1.0	0.3743540905035634	3	P61160	1
+Enolase, conserved site [IPR020809]	0.5544492843808413	0.9843128569744528	0.3249617098582602	1.0	0.3827938785618489	2	P09104	1
+Zinc finger, RING-type, conserved site [IPR017907]	0.3776143663680864	0.9786596232189704	0.3277481886203646	1.0	0.3844472423479382	17	Q8TDB6	1
+ATPase, AAA-type, conserved site [IPR003960]	0.3600801129439109	0.9670581692879588	0.3335149553242491	1.0	0.3895678889921901	19	P35998,P43686,Q9UN37,P17980,P55072,Q15645,P62333,P62195	8
+Dynamin, GTPase region, conserved site [IPR019762]	0.5429371499688914	0.9309136768545327	0.3518982191589397	1.0	0.4076154371924385	2	O00429	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.52535533933505	0.8889648961521934	0.3740219460520633	1.0	0.4314444024998904	6	P33991,P49736,P33993,P33992	4
+4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]	0.5255133789670283	0.8509326259184494	0.3948067799671872	1.0	0.4516719540365352	2	P61221	1
+Adenylate kinase, conserved site [IPR033690]	0.539697982104644	0.6256318951622722	0.5315564133521928	1.0	0.587758821322709	3	P00568	1
+ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]	0.4247044181705056	0.4264151650961025	0.6698053529139296	1.0	0.7134325214945304	2	P53396	1
+DNA ligase, ATP-dependent, conserved site [IPR016059]	0.4200373366521485	0.4092249138835256	0.6823746125882888	1.0	0.7240463446547492	2	P18858	1
+DnaJ domain, conserved site [IPR018253]	0.3540207101056419	0.3667027449423556	0.7138407588259319	1.0	0.7545541100897684	9	Q8WXX5,Q5F1R6,P31689,Q96KC8	4
+Heat shock protein 70, conserved site [IPR018181]	0.3522528387330115	0.3590799889193491	0.7195352512145501	1.0	0.7576924236274429	9	P11142,Q92598,P34932,P54652,O95757,Q0VDF9	6
+Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]	0.3472308649657739	0.1858473152242973	0.8525644986493022	1.0	0.8763831878752523	2	P11586	1
+Ribosomal S11, conserved site [IPR018102]	0.3024268823895414	0.0976836472222525	0.9221835010740772	1.0	0.9332452507806828	2	P62263	1
+Ras GTPase-activating protein, conserved site [IPR023152]	0.3401805166511028	0.0882053862006013	0.9297134364366204	1.0	0.9364504903238424	3	P46940,P21359	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AF4 interaction motif [IPR043639]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Argininosuccinate synthase, conserved site [IPR018223]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Bromodomain, conserved site [IPR018359]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Deoxyribonuclease, TatD-related, conserved site [IPR018228]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Endonuclease III-like, conserved site-2 [IPR004036]", "Endonuclease III-like, iron-sulphur cluster loop motif [IPR003651]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Folylpolyglutamate synthetase, conserved site [IPR018109]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamine synthetase, N-terminal conserved site [IPR027302]", "Glutamine synthetase, glycine-rich site [IPR027303]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "GoLoco motif [IPR003109]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif [IPR000445]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H4, conserved site [IPR019809]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M22, conserved site [IPR017860]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidyl-prolyl cis-trans isomerase, PpiC-type, conserved site [IPR023058]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosyl pyrophosphate synthetase, conserved site [IPR000842]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S14, conserved site [IPR018271]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor, T-box, conserved site [IPR018186]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB10", "ABCB7", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSS1", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFF4", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA6", "ANXA7", "AP1M1", "AP1S2", "AP2M1", "AP2S1", "AP3M1", "APAF1", "APEX1", "ARIH2", "ARRB2", "ARSA", "ASS1", "ATAD1", "ATAD2", "ATAD2B", "ATP5C1", "ATP5O", "BAG6", "BARD1", "BAZ1A", "BAZ1B", "BAZ2A", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BRD3", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBR4", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CECR2", "CHAF1B", "CHD1", "CHD1L", "CHD4", "CIAO1", "CLGN", "CMPK1", "CNDP2", "COPA", "COPZ1", "CORO1A", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4A", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX31", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHRS11", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DIS3L", "DLG3", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC2", "DNAJC21", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DRG1", "DRG2", "DSC1", "DSC2", "DSG2", "DTL", "DTX3L", "DTYMK", "DUS1L", "DUS2", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FARP2", "FBL", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXC1", "FOXK1", "FPGS", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GLUL", "GMPPA", "GMPR2", "GNB1", "GNB2", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPSM1", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF3C2", "GUF1", "H4C1*", "HADH", "HADHA", "HADHB", "HIBADH", "HINT1", "HINT2", "HLA-A", "HLTF", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "IDH3G", "ILVBL", "IMPA1", "IMPDH1", "IMPDH2", "ING2", "IQGAP1", "IQGAP3", "ISCA2", "IVD", "KDM2A", "KDM5A", "KIF11", "KIF13B", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "LAMP1", "LARS", "LARS2", "LBR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRWD1", "LSS", "MACF1", "MAPK1", "MAPK14", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGA", "MGST2", "MID1", "MIF", "MOCS1", "MPI", "MPP2", "MPP6", "MPST", "MRPL13", "MRPL24", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTF2", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "MVK", "N6AMT1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFV1", "NF1", "NKTR", "NLE1", "NMT1", "NNT", "NOP2", "NSD1", "NSD2", "NSF", "NTHL1", "NUBP2", "NUBPL", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OSBP", "OSBPL11", "OSBPL8", "OSBPL9", "OSGEP", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA5", "PDIA6", "PDSS1", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PIN1", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIG", "PPIH", "PPIL1", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKAR2B", "PRKDC", "PRPF19", "PRPF4", "PRPS1", "PRPS2", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAD18", "RAE1", "RANBP2", "RARS", "RBBP4", "RCL1", "RDH13", "RDX", "RECQL5", "RIDA", "RIOK2", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS29", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RSL24D1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SEC61A1", "SERPINB6", "SERPINH1", "SLC1A5", "SLC27A4", "SLIT2", "SMARCA4", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SRCAP", "SRM", "STMN1", "STRN", "STX12", "STX18", "STX4", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SYNE1", "SYNE2", "TATDN1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM25", "TRIM27", "TRIM28", "TRIM33", "TRIM56", "TRIP13", "TRMT11", "TSFM", "TTF2", "TUBB", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UBA5", "UHRF1", "USP1", "USP10", "USP14", "USP19", "USP22", "USP24", "USP28", "USP36", "USP38", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VCL", "VCP", "VIM", "VPS4A", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR48", "WDR5", "WDR61", "WDR77", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZMYND8"], "leading_proteins": ["ABCE1", "ACLY", "ACTR2", "AHCY", "AK1", "AKR1B1", "ALDOA", "AP2S1", "BPNT1", "CAPZA2", "CCT2", "CCT3", "CCT5", "CCT6A", "CCT7", "CCT8", "COPZ1", "CRYZ", "CTBP1", "DNAJA1", "DNAJC1", "DNAJC21", "DNAJC9", "DNM1L", "DRG2", "DTX3L", "DUS1L", "DUS3L", "EEF1A2", "ENO2", "EPS15", "FOXK1", "GRHPR", "HINT1", "HMGB1", "HMGB3", "HSPA14", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPH1", "IMPDH1", "IMPDH2", "IQGAP1", "LIG1", "MCM2", "MCM4", "MCM5", "MCM7", "MIF", "MTAP", "MTHFD1", "N6AMT1", "NF1", "PFKL", "PFKM", "PGM1", "PGM3", "PHGDH", "PRKAR1A", "PRPS1", "PSMA4", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PYGB", "RPL7", "RPS14", "SMS", "TCP1", "TRIP13", "TUBB2A", "TUBB4A", "TUBB4B", "TUBB6", "UBA2", "USP1", "USP14", "USP22", "USP28", "USP38", "USP48", "USP5", "VCP", "VPS4A"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Glutathione S-transferase, C-terminal-like [IPR010987]", "1": "Glutathione S-transferase, N-terminal [IPR004045]", "2": "Glutathione S-transferase, C-terminal [IPR004046]", "3": "SH2 domain [IPR000980]", "4": "Proteasome alpha-subunit, N-terminal domain [IPR000426]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Glutathione S-transferase, C-terminal-like [IPR010987]", "1": "Glutathione S-transferase, N-terminal [IPR004045]", "2": "Glutathione S-transferase, C-terminal [IPR004046]", "3": "SH2 domain [IPR000980]", "4": "Proteasome alpha-subunit, N-terminal domain [IPR000426]", "5": "Phosphoribosyltransferase domain [IPR000836]", "6": "Actin-depolymerising factor homology domain [IPR002108]", "7": "Serine-threonine/tyrosine-protein kinase, catalytic domain [IPR001245]", "8": "THIF-type NAD/FAD binding fold [IPR000594]", "9": "Protein kinase domain [IPR000719]", "10": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "11": "Ubiquitin specific protease domain [IPR028889]", "12": "SH3 domain [IPR001452]", "13": "ATPase, AAA-type, core [IPR003959]", "14": "Ubiquitin-like domain [IPR000626]", "15": "Calponin homology domain [IPR001715]", "16": "Proteasome component (PCI) domain [IPR000717]", "17": "K Homology domain [IPR004087]", "18": "Small GTP-binding protein domain [IPR005225]", "19": "K Homology domain, type 1 [IPR004088]", "20": "AAA ATPase, AAA+ lid domain [IPR041569]", "21": "TOG domain [IPR034085]", "22": "GOLD domain [IPR009038]", "23": "AAA+ ATPase domain [IPR003593]", "24": "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "25": "MPN domain [IPR037518]", "26": "Importin-beta, N-terminal domain [IPR001494]", "27": "Zinc finger, LIM-type [IPR001781]", "28": "EF-hand domain [IPR002048]", "29": "Serine/threonine-specific protein phosphatase/bis(5-nucleosyl)-tetraphosphatase [IPR006186]", "30": "Protein kinase C-like, phorbol ester/diacylglycerol-binding domain [IPR002219]", "31": "GTP binding domain [IPR006073]", "32": "BTB/POZ domain [IPR000210]", "33": "Calcineurin-like phosphoesterase domain, ApaH type [IPR004843]"}