msigdb_reactome/result.tsv

Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
Tnfr2 non canonical nf kb pathway	0.6789107373183666	4.870472797402803	1.1133152848508132e-06	0.0015374195380121	0.0002167129250018	44	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,O15111,P25787,P61289,Q13616,Q12933,P20618,O00233,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231,Q8TBC4	40
Dectin 1 mediated noncanonical nf kb signaling	0.6779479060127231	4.864835525987275	1.145520258205579e-06	0.0015818574461136	0.0002167129250018	43	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,O15111,P25787,P61289,Q13616,P20618,O00233,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231,Q8TBC4	39
Cross presentation of soluble exogenous antigens endosomes	0.6743132974226157	4.852298028743088	1.2203904340424288e-06	0.0016851591311742	0.0002167129250018	38	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	34
Degradation of axin	0.6743132974226157	4.852298028743088	1.2203904340424288e-06	0.0016851591311742	0.0002167129250018	38	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	34
Scf skp2 mediated degradation of p27 p21	0.6734902029546882	4.829860627925958	1.3662865003816194e-06	0.0018864276878785	0.0002167129250018	42	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,Q13616,P20618,O00233,Q13309,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,P11802,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	38
Regulation of runx3 expression and activity	0.6694603087398577	4.802757760279267	1.5649516766913507e-06	0.0021604278186366	0.0002167129250018	40	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P12931,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P42771,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	36
Nervous system development	0.3811424282449245	4.789448642698659	1.6724019280545122e-06	0.0023085924892064	0.0002167129250018	221	O14786,P61247,P43686,P28070,Q04637,P62847,P62244,P62191,P62750,P59998,P26038,Q16512,P48556,Q14195,Q96S59,P42766,Q16539,P62899,Q9Y490,P08238,P62081,Q00535,O43242,O14818,O14531,P08708,P47914,P18124,P62701,P61353,P25788,P62841,P62269,Q9BUF5,Q06323,Q9UL46,Q15369,P62495,Q13200,P62333,Q06124,Q02750,P25787,P61289,P35998,P25789,Q92530,P49721,Q9Y3U8,P17980,P15311,P11142,O75122,P25786,P15170,P62854,P68371,P62906,Q05397,P51665,P46939,P46782,O00232,P05388,P04350,Q13885,P12931,P19784,P20618,P46781,O00487,P28074,O00401,Q13177,Q15008,P61160,P62277,P62861,Q9BPU6,O15145,P49720,O00231,Q9UNM6,Q96P70,P16333,O75832,P62195,Q99460,Q99436,Q16555,Q12955,P15880,O00233,O15144,O95239,P08865,P28072,P46778,P62910,P55036,P60900,P35579,Q7Z406,Q15370,P28066,P84098,Q13464,P23396	108
Cdt1 association with the cdc6 orc origin complex	0.6671169590481618	4.77896755872236	1.7619761809584134e-06	0.0024320908902001	0.0002167129250018	41	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,O43929,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	35
Cyclin a cdk2 associated events at s phase entry	0.6666222263239222	4.76515807851149	1.8870564590933725e-06	0.0026045168323635	0.0002167129250018	44	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P06400,Q13616,P20618,O00233,Q13309,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,P11802,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	39
Adaptive immune system	0.3743262921499335	4.751595419330548	2.0181788014106417e-06	0.0027852399200214	0.0002167129250018	199	Q08209,Q8TDB6,P43686,P28070,P62191,P61163,Q16512,P48556,P61086,P47755,Q92990,Q9BXS5,Q9NXK8,Q9UNE7,Q14204,Q13309,O43747,O43242,O14818,O95376,P25788,P50570,Q9BUF5,Q9C0C9,Q06323,P62942,Q9UL46,Q9Y496,Q15369,A0AVT1,Q13200,P62333,Q9NZ32,Q9Y6G9,Q06124,P22314,O15111,P25787,O43237,P61289,Q5T447,P35998,P30153,P31946,P30154,P25789,Q92530,Q7Z6Z7,P49721,Q15386,P17980,P25786,Q13561,P55786,P68371,P51665,Q9NZ08,P52888,O00161,Q7Z7E8,O00232,Q5VTB9,P09429,P04350,Q9H0H5,Q9UII4,P61088,Q13885,P52907,P12931,P20618,P41240,O00487,P28074,P68036,O95352,Q13177,O95486,Q15436,Q15008,Q93034,P49720,O00231,Q8TBC4,Q9UNM6,Q96ME1,P16333,Q14203,O75832,P62195,Q99460,Q99436,Q07866,Q8IWV7,Q13616,O00233,O95239,O43865,P63208,P28072,Q05086,P60900,P55036,P61081,Q15370,Q8NEZ5,O75935,P28066	108
Degradation of dvl	0.6633214685843721	4.750473333658731	2.0294105635976223e-06	0.0028007188932385	0.0002167129250018	40	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	34
Negative regulation of notch4 signaling	0.6640976935692071	4.749565250305836	2.0385441570347496e-06	0.0028133061131012	0.0002167129250018	42	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,Q13616,P20618,O00233,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,Q9Y6A5,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	37
Interleukin 1 signaling	0.6626440714105333	4.724042244030804	2.312023575479216e-06	0.0031901209912818	0.000218944503382	47	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,P09429,O75832,P62195,Q99460,P48556,Q99436,P61088,O15111,Q02750,P25787,P61289,Q13616,P20618,O00233,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	40
Tcr signaling	0.6600391282789699	4.698383480648955	2.622287221143438e-06	0.0036174469080053	0.000218944503382	49	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,P16333,O75832,P62195,Q16512,Q99460,P48556,Q99436,P61088,O15111,P25787,P61289,Q13616,P20618,O00233,P41240,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q13177,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	42
Fceri mediated nf kb activation	0.6586330083690111	4.693411398873051	2.6868638864918637e-06	0.0037063652888662	0.000218944503382	45	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P61088,O15111,P25787,P61289,Q13616,P20618,O00233,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	38
Stabilization of p53	0.6556322243571449	4.684610809015603	2.8049239033656193e-06	0.0038689066914607	0.000218944503382	40	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P42771,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	35
Asymmetric localization of pcp proteins	0.6547145712945941	4.68122445497764	2.85166502234091e-06	0.0039332511048714	0.000218944503382	39	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	34
Regulation of ras by gaps	0.6541871745895949	4.664168075818043	3.098680455337899e-06	0.0042732266969303	0.0002253882310146	42	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P21359,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	35
G1 s dna damage checkpoints	0.6498998450212762	4.627007460380143	3.7098715566230567e-06	0.0051139311039179	0.0002517658866713	42	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P42771,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,O14757,P49720,O00231	36
Auf1 hnrnp d0 binds and destabilizes mrna	0.6495823287463598	4.620634867068436	3.8256755572341206e-06	0.0052731416528671	0.0002517658866713	43	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,Q04637,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q15008,P25788,P28066,P17980,Q06323,P11142,P25786,Q9UL46,P49720,O00231	37
Downstream signaling events of b cell receptor bcr	0.6483034614312778	4.603215842890434	4.160166788391706e-06	0.0057328665052511	0.0002571617422048	45	P51665,Q08209,Q13200,P62333,Q9UNM6,P43686,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,O15111,P25787,P61289,Q13616,P20618,O00233,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q15008,P25788,P28066,P17980,Q06323,P62942,P25786,Q9UL46,P49720,O00231	40
Metabolism of polyamines	0.6451779442463353	4.58998880059735	4.432697926048945e-06	0.0061072764176283	0.0002571617422048	41	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,P62191,O00232,P19623,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	37
Clec7a dectin 1 signaling	0.6477287745170606	4.588430666970155	4.465905798056724e-06	0.0061528885700904	0.0002571617422048	50	P51665,Q08209,Q13200,P62333,Q9UNM6,P43686,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P61088,O15111,P25787,P12931,P61289,Q13616,P20618,O00233,O43865,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P61081,P60900,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231,Q8TBC4	44
Regulation of runx2 expression and activity	0.640665427190612	4.530730656747154	5.87800394313831e-06	0.0080905194677474	0.0003143337503073	47	P51665,P11474,Q13200,P62333,Q9UNM6,P43686,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,Q13616,P20618,O00233,Q13309,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231,P42224	39
Signaling by the b cell receptor bcr	0.6378918320517187	4.502026535908854	6.730857539549717e-06	0.0092589459501877	0.0003286846397047	49	P51665,Q08209,Q13200,P62333,Q9UNM6,P43686,P28070,O00232,P16333,O75832,P62195,Q99460,P48556,Q99436,O15111,P25787,P61289,Q13616,P20618,O00233,O43865,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q15008,P25788,P28066,P17980,Q06323,P62942,P25786,Q9UL46,P49720,O00231	42
Interleukin 1 family signaling	0.6376119419356505	4.496838145141204	6.897145116813164e-06	0.0094866029802451	0.0003286846397047	51	P51665,Q13200,P62333,P43686,Q9UNM6,P40763,P28070,O00232,P09429,O75832,P62195,Q99460,P48556,Q99436,P61088,Q06124,O15111,Q02750,P25787,P61289,Q13616,P20618,O00233,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	42
Orc1 removal from chromatin	0.6355495278425619	4.477385335141629	7.556278898590563e-06	0.0103884799879306	0.0003408722234059	52	P51665,Q13200,P62333,Q9UNM6,P43686,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,Q13616,P20618,O00233,Q13309,P35998,O43929,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P63208,P49721,P60900,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P33991,P33992,P49720,O00231,P49736	42
Regulation of pten stability and activity	0.6320133876221548	4.470530233486858	7.802591250438695e-06	0.0107252926386157	0.0003408722234059	42	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,P62191,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P19784,P61289,Q9UNE7,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	38
Runx1 regulates transcription of genes involved in differentiation of hscs	0.6312343699519971	4.468070094147367	7.89284453617256e-06	0.0108486781865034	0.0003408722234059	41	P51665,P62805,Q13200,P62333,Q9UNM6,P43686,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	35
Fc epsilon receptor fceri signaling	0.6290573551009387	4.4174840836521545	9.985642115850624e-06	0.0137054397097	0.0003967225552961	54	P51665,Q08209,Q13200,P62333,Q9UNM6,P43686,P28070,O00232,O75832,P62195,Q16512,Q99460,P48556,Q99436,P61088,O15111,P25787,P61289,Q13616,P20618,O00233,O43865,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q13177,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	43
Cellular response to hypoxia	0.6256547896850517	4.4101185096144615	1.0331406311570037e-05	0.0141766289366665	0.0003967225552961	43	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,Q15369,P49720,O00231	36
Regulation of hmox1 expression and activity	0.6276578889724578	4.410057724065094	1.0334306794979042e-05	0.0141805806110853	0.0003967225552961	49	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P19784,P61289,Q13616,P20618,O00233,Q13309,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	38
Degradation of gli1 by the proteasome	0.6227868899997588	4.384599122095584	1.1619956379771423e-05	0.0159306167853843	0.0004225994662327	43	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,Q13616,P20618,O00233,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	36
Hedgehog on state	0.6222488623498617	4.372218840282551	1.2299015145433856e-05	0.0168537035976538	0.0004249309732747	45	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,Q9Y496,P49720,O00231	35
The role of gtse1 in g2 m progression after g2 checkpoint	0.6223794467616255	4.360398521929793	1.2982577967557418e-05	0.0177820391707929	0.0004327345077472	50	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,P04350,Q99460,P48556,Q99436,Q15691,Q13885,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,Q9BUF5,P28066,P17980,P14635,Q06323,P25786,Q9UL46,P68371,P49720,O00231	40
Mapk6 mapk4 signaling	0.6220689855584668	4.357575381239105	1.3151121074805872e-05	0.0180108001814358	0.0004327345077472	50	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,P62191,O00232,O75832,P62195,Q16512,Q99460,P48556,Q99436,P25787,Q9HCE1,P61289,P20618,O00233,P25685,P35998,O14980,P28072,O00487,P25789,O14818,P28074,Q92530,P55036,O43242,P49721,P60900,Q13177,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	42
C type lectin receptors clrs	0.6216445097411705	4.34929082289756	1.36578488860728e-05	0.018698253568034	0.0004389569107105	55	P51665,Q08209,Q13200,P62333,Q9UNM6,P43686,P28070,O00232,O75832,P62195,Q16512,Q99460,P48556,Q99436,P61088,O15111,P25787,P12931,P61289,Q13616,P20618,O00233,O43865,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P61081,P60900,Q13177,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231,Q8TBC4	46
Hedgehog ligand biogenesis	0.6087692570229668	4.273877069710044	1.9210297657501485e-05	0.0261995628960931	0.0005638684139656	40	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	34
Degradation of beta catenin by the destruction complex	0.612631441341154	4.269576680815831	1.9584431165231564e-05	0.0267029484688325	0.0005638684139656	51	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,Q13616,P20618,O00233,P35998,P30153,P63208,P28072,O00487,P25789,P28074,Q92530,P30154,P55036,O43242,P49721,P60900,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,Q04726,P49720,O00231	40
Signaling by notch4	0.6053925730093074	4.22407498936339	2.3992415872697848e-05	0.0326142186571892	0.0006766840558381	44	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,Q13616,P20618,O00233,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,Q9Y6A5,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	37
Neddylation	0.5883449584280871	4.179285182176533	2.924267962334248e-05	0.0396082205218245	0.0007625166648954	85	P51665,Q13200,P62333,P43686,P61201,P28070,Q86VX2,Q9UNM6,Q96ME1,Q7L5N1,O00232,Q13619,O75832,P62195,Q99460,P48556,Q9P000,Q99436,Q92905,P25787,P61289,Q13616,P20618,O00233,Q9NZJ0,Q9BW61,Q13309,P35998,Q9BTE7,P63208,O43242,O00487,P25789,Q92530,Q9UBI1,P28074,P49721,P28072,P60900,P55036,P61081,Q15008,Q13564,P25788,Q86VP6,Q93034,Q15370,Q96GG9,Q99627,Q9NXF7,Q9UNS2,Q9BT78,P17980,Q06323,P28066,P25786,Q9UL46,Q15369,P49720,O00231,Q8TBC4	61
Mitotic g1 phase and g1 s transition	0.5911367749447687	4.150570717690652	3.316472775072299e-05	0.0447998829448463	0.0008266173597963	79	P51665,O00231,Q13200,P62333,P43686,Q9UNM6,P28070,P12004,O00232,O75832,P31350,P62195,Q99460,P48556,Q99436,P63151,P35244,P25787,P12931,P04183,P06400,P61289,P09884,Q13616,P49643,P20618,O00233,P49642,Q13309,P35998,P30153,O43929,O43242,Q00534,P30154,P25789,Q92530,P42771,P11802,P49721,O00487,P28074,P55036,P63208,Q15008,P25788,P28072,P27694,P17980,Q06323,P14635,P28066,P25786,Q9UL46,P49720,P33991,P49736	57
Uch proteinases	0.598698656068562	4.148299861337561	3.349534887742145e-05	0.0452362462964319	0.0008266173597963	48	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,Q9Y265,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P85037,Q15008,P25788,Q9Y5K5,P28066,P17980,Q06323,Q16186,P25786,Q9UL46,P49720,O00231	38
Dna replication pre initiation	0.5956873312663313	4.112769937115678	3.909399350709997e-05	0.0525953261279629	0.0009157271021493	63	P51665,P62805,Q13200,P62333,Q9UNM6,P43686,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P35244,P25787,P09884,P61289,P49643,P20618,O00233,P49642,P35998,O43929,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q15008,P25788,Q14974,P27694,P28066,P17980,Q06323,P25786,Q9UL46,P33991,P33992,P49720,O00231,P49736	46
Transcriptional regulation by runx2	0.595419456202421	4.103945019688344	4.06164027557665e-05	0.0545866205606876	0.0009355311434745	56	P51665,P11474,Q13200,P62333,Q9UNM6,P43686,P28070,P62191,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P12931,P61289,P06400,Q13616,Q9UNE7,P20618,O00233,Q13309,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,P11802,O43242,P49721,P60900,Q15008,P25788,P28066,P17980,P14635,Q06323,P25786,Q9UL46,Q13485,P49720,O00231,P42224	47
Hedgehog off state	0.5906198622743649	4.061473796607193	4.8763892306347145e-05	0.0651725782158679	0.001061569562311	53	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,P04350,Q99460,P48556,Q99436,Q13885,P25787,P61289,Q13616,P20618,O00233,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,Q8NCM8,Q9BUF5,P28066,P17980,Q06323,P25786,Q9UL46,Q9Y496,P68371,P49720,O00231	42
Defective cftr causes cystic fibrosis	0.5832763462965527	4.031797427350736	5.535188846828021e-05	0.0736456286021942	0.0011417359681069	42	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	34
Abc transporter disorders	0.5832763462965527	4.031797427350736	5.535188846828021e-05	0.0736456286021942	0.0011417359681069	42	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	34
Pcp ce pathway	0.5725724060950373	3.892231056299155	9.932658006106544e-05	0.1282705363715515	0.0018804018307451	52	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	34
Transcriptional regulation by runx3	0.5680154327917978	3.869754274451378	0.0001089451032276	0.1397827752923501	0.002034623414333	46	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P12931,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P42771,P60900,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,Q13485,P49720,O00231	38
Signaling by robo receptors	0.4520353183971543	3.862658763650659	0.0001121596264963	0.1435962102765572	0.0020667280509061	142	P51665,P62495,O14786,Q13200,P61247,P43686,P28070,Q04637,P62847,P62244,P62191,P62750,P62333,P46782,O00232,P05388,P16333,Q16512,O75832,P62195,Q99460,P48556,Q99436,P23396,P42766,P25787,P12931,P61289,P62899,P20618,Q9UNM6,P15880,O00233,P35998,P62081,P46781,P08865,O43242,O00487,P25789,O14818,Q92530,P08708,P49721,P28074,P28072,P46778,P47914,P18124,P62701,Q13177,P55036,Q15008,P25788,P62277,Q9Y3U8,P62861,P62841,P62269,Q15370,P17980,Q06323,P62910,P28066,P84098,O75122,P25786,Q9UL46,P15170,P49720,Q15369,P60900,P62854,P62906,O00231	75
Metabolism of amino acids and derivatives	0.3280515137772821	3.782721049004597	0.0001551232280234	0.1929720126079653	0.0027841597549147	195	Q13126,Q9Y617,P61247,P43686,P28070,P62847,P62244,P62191,P62750,P52788,P48556,P42766,P62899,P62081,O43242,O14818,P08708,P47914,P18124,P62701,P61457,P61353,P25788,P62841,P62269,Q06323,Q9UL46,O95340,O43175,P12277,Q9BV20,Q13200,P62333,P25787,P61289,P11182,P54136,P35998,P25789,Q92530,P49721,Q9Y3U8,Q13155,P17980,P00966,P25786,P25325,P62854,P62906,Q99707,P51665,P46782,P34896,O00232,P05388,P19623,P20618,P49591,P46781,O00487,P28074,Q15008,P62277,P62861,P23526,P49720,O00231,Q9UNM6,O75832,P62195,Q99460,Q99436,Q14353,P17174,P15880,O00233,O43252,O43324,P16930,P08865,P28072,P46778,P62910,P55036,P60900,P28066,P84098,Q7L266,P41252,P23396	90
Membrane trafficking	0.3347937279443636	3.733288244029944	0.0001889960950476	0.2298864355087734	0.0033062354855168	234	Q9Y5X3,Q9UJY4,P61163,P59998,P27348,Q99816,P40616,P50395,P47755,Q5H9R7,Q9BXS5,Q86SZ2,Q9BXI6,P42566,Q14247,Q9NVG8,Q14204,O43747,O43264,P53618,Q96JB2,P54646,P61020,Q8WUX9,P50570,P48444,P47756,Q99627,O15027,Q9BUF5,Q9NP79,Q15363,P84085,Q9Y496,Q96KP1,O15260,P60520,P61201,P62258,Q9NQT8,Q92538,Q9NZ32,Q9BZE9,Q9Y6G9,O43237,Q96D71,P51148,P31946,Q13492,Q9Y5X1,O00471,Q99961,Q9UNS2,P11142,O60664,Q4KMP7,Q13561,P68371,Q8N6T3,O00161,Q7L5N1,P33908,P04350,Q9H0H5,Q9Y6I3,Q13885,P22681,P52594,P52907,O14976,O15498,P12931,P68402,Q9NVZ3,O00401,Q8IUR0,Q15642,O95486,Q15436,P61160,Q8TC07,Q9UN37,Q9BT78,Q7Z6M1,O00743,O15145,P35606,O00443,Q15102,Q14203,P62330,Q07866,Q9Y678,Q9UID3,Q92905,Q9H0V9,Q12955,P20336,O15144,O95239,O60343,P18085,Q04917,P35579,Q86VN1,Q14C86,Q7Z392,O75935,O60645,Q9UBF2,Q10471	111
Signaling by hedgehog	0.5386381517823948	3.548447948848835	0.0003875085800078	0.4147057969365113	0.0063754387806045	59	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,P04350,Q99460,P48556,Q99436,Q13885,P25787,P61289,Q13616,P20618,O00233,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,Q8NCM8,Q9BUF5,P28066,P17980,Q06323,P25786,Q9UL46,Q9Y496,P68371,P49720,O00231	42
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1	0.5352526921164723	3.533512581741266	0.0004100765710894	0.4326858393708133	0.0065898351307636	51	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P06400,P20618,O00233,Q13309,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	36
Synthesis of dna	0.5267917391235574	3.5294574058729498	0.0004164127298618	0.4376339153830726	0.006614740145621	86	P51665,O00231,Q13200,P62333,P43686,Q9UNM6,P28070,P12004,O00232,O75832,P62195,Q99460,P48556,Q99436,Q15054,P35244,P25787,Q9BRT9,P61289,P09884,Q13616,P49643,P20618,O00233,P49642,Q13309,P35998,P35250,O43929,O43242,O00487,Q9BRX5,P25789,P39748,Q92530,P49721,P28340,P28074,P28072,P55036,P40937,P63208,Q15008,P25788,P27694,P17980,Q06323,P28066,P25786,Q9UL46,P49720,P33991,P49736	53
Tcf dependent signaling in response to wnt	0.5361635907816771	3.52219010868292	0.0004279971018192	0.4465692288002173	0.0067214999399347	62	P51665,P62805,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,Q9Y265,Q9HCK8,P25787,P19784,P61289,P20618,O00233,P35998,P30153,O14980,P28072,O00487,P25789,P28074,Q92530,P30154,P55036,P49721,P60900,O43242,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,Q04726,P49720,O00231	43
Trna modification in the nucleus and cytosol	0.6337848947182669	3.476002781276065	0.0005089470078649	0.5051713872910946	0.0078151640541043	22	Q9UI30,Q9UBP6,Q96BT7,Q9Y3C4,Q6YHU6,Q96S44,Q9NPF4,O60294,Q08J23,Q2VPK5	10
Antigen processing ubiquitination proteasome degradation	0.5033801278261981	3.4583102724357313	0.0005435749798916	0.5283060282424307	0.0082551716726403	102	P51665,P52888,Q13200,P62333,Q8TDB6,P43686,P28070,Q9UNM6,Q7Z7E8,Q96ME1,O00232,Q5VTB9,O75832,P62195,Q99460,P48556,Q99436,P61086,Q9UII4,P61088,Q92990,Q8IWV7,P22314,P25787,P61289,Q13616,Q5T447,P20618,O00233,Q13309,P35998,P63208,O43242,O00487,P25789,Q92530,P28074,P28072,Q7Z6Z7,P49721,O95376,P68036,O95352,Q15386,Q05086,P60900,P55036,P61081,Q15008,P25788,Q93034,Q15370,Q9C0C9,P17980,Q06323,P28066,P25786,Q9UL46,Q15369,P55786,P49720,O00231,Q8TBC4,A0AVT1	64
Apc c mediated degradation of cell cycle proteins	0.5287131261254149	3.4483795871717193	0.0005639608639445	0.5414169045602193	0.0084716729779489	59	P51665,O43684,Q13200,P62333,Q9UNM6,P43686,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P06400,Q13616,P20618,O00233,Q13309,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q15008,P25788,P28066,P17980,P14635,Q06323,P25786,Q9UL46,O60566,P49720,O00231	42
Dna strand elongation	0.5847137483828793	3.4383454861921225	0.0005852804478272	0.5547388769583307	0.0086973933214757	27	Q15054,Q9BRX5,P39748,P27694,P35244,P40937,P09884,Q9BRT9,P12004,P49643,P49642,P33991,P49736,P35250	14
Dna replication	0.5146700158068532	3.433178245831055	0.0005965497782414	0.5616237848888888	0.008740726317446	90	P51665,O00231,P62805,Q13200,P62333,P43686,Q9UNM6,P28070,P12004,O00232,O75832,P62195,Q99460,P48556,Q99436,Q15054,P35244,P25787,Q9BRT9,P61289,P09884,Q13616,P49643,P20618,O00233,P49642,Q13309,P35998,P35250,O43929,O43242,O00487,Q9BRX5,P25789,P39748,Q92530,P49721,P28340,P28074,P28072,P60900,P55036,P40937,P63208,Q15008,P25788,Q14974,P27694,P17980,Q06323,P28066,P25786,Q9UL46,P33992,P49720,P33991,P49736	57
Regulation of expression of slits and robos	0.4625892451853363	3.431232281039899	0.0006008458756565	0.5642203538036948	0.008740726317446	125	P51665,P62495,Q13200,P62333,P61247,P43686,P28070,Q04637,P62847,P62244,P62191,P62750,P46782,O00232,P05388,O75832,P62195,Q99460,P48556,Q99436,P23396,P42766,P25787,P61289,P62899,P20618,Q9UNM6,P15880,O00233,P35998,P62081,P46781,P08865,O43242,O00487,P25789,O14818,Q92530,P08708,P49721,P28074,P28072,P46778,P47914,P18124,P62701,P62910,P55036,Q15008,P25788,P62277,Q9Y3U8,P62861,P62841,P62269,Q15370,P17980,Q06323,P28066,P84098,P25786,Q9UL46,P15170,P49720,Q15369,P60900,P62854,P62906,O00231	69
Switching of origins to a post replicative state	0.5263376102080356	3.422443795182466	0.0006206092702716	0.5759688096816158	0.0089307490977954	61	P51665,Q13200,P62333,Q9UNM6,P43686,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,Q13616,P20618,O00233,Q13309,P35998,O43929,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,P63208,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P33991,P33992,P49720,O00231,P49736	42
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand	0.5544563170807508	3.4197302467542365	0.0006268326067193	0.5796023723649905	0.0089307490977954	31	O60884,P54652,P0DMV9,P31689,P61163,Q14203,P04350,Q9NZ32,P47755,Q9Y6G9,Q13885,Q9UJW0,P52907,Q13451,O43237,P25685,Q14204,P08238,P31948,Q15185,P47756,O75935,Q9BUF5,P11142,Q13561,P68371,Q02790	27
Mitotic g2 g2 m phases	0.5108619688298836	3.4005781218628774	0.0006724351850839	0.6052955471447754	0.0094827084263883	91	P51665,Q13200,P62333,P43686,O94927,P28070,P62258,Q9UNM6,Q96ME1,O00232,Q14203,P04350,O75832,P62195,P48556,Q99460,Q99436,P63151,Q15691,Q13885,P25787,P07437,P61289,Q13616,P20618,P21127,O00233,Q9Y570,P35998,P30153,O14980,O43242,P30154,P25789,Q92530,O00487,P28074,P49721,P63208,P28072,P55036,Q96CS2,Q15008,P25788,Q96CW5,Q9H6D7,O75935,Q9BUF5,P17980,Q06323,P14635,P28066,P25786,Q9UL46,Q13561,P68371,P49720,O00231	58
Innate immune system	0.3285122908011684	3.372952279241975	0.000743668401804	0.6423255534059342	0.0102774973129321	287	Q9UJU6,P43686,P28070,P04075,P06744,O00764,P42575,Q16512,Q9P000,P48556,P50395,P61086,P47755,Q16539,Q9Y6W5,Q14258,O14727,O43242,Q6SZW1,P13639,P13798,P53618,P50990,P25788,Q92820,Q99439,Q06323,P07741,Q9UL46,O15260,P09960,P18669,P53990,Q13200,P62333,Q96G03,Q15366,Q9NZ32,Q9UQB8,Q9Y6G9,Q06124,O15111,Q02750,P25787,Q9Y315,O75874,P61289,P12268,P51148,P35998,P30153,P30154,P25789,Q92530,Q7Z6Z7,P49721,P17858,O75575,P20839,P17980,P11142,P25786,P78371,P68371,Q05397,P51665,Q9NQR4,P36543,O00161,O00232,P09429,Q9UII4,P61088,P52907,P07437,P12931,P15924,P20618,P68402,O00487,Q9UBI1,P28074,P30041,O00401,O95352,P04080,Q13177,Q15008,P61160,Q9UI12,Q9BRF8,P35237,P21283,P13010,P09972,P14174,P36871,O15145,P49720,O00231,Q8TBC4,P51452,P46940,Q9UNM6,Q9Y2Z0,P16333,P31949,O75832,P62195,Q99460,Q99436,Q9BUI4,Q08554,Q13616,P20336,Q12933,P12956,O15144,O00233,O43865,P63208,P28072,P60900,P55036,P61081,P35579,Q86VP6,O60610,Q14974,P28066,Q13464	131
Abc family proteins mediated transport	0.5157503961158819	3.344325747995858	0.0008248282669938	0.6803034581228581	0.0111756143626024	50	P51665,P41091,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P40855,P49720,O00231	37
Myd88 independent tlr4 cascade	0.6482165961492752	3.279565584612354	0.0010396704164024	0.7624962688529819	0.0139497525773604	19	P63208,P30154,P61088,Q06124,Q6SZW1,O15111,Q02750,Q16539,Q13616,P09429	10
Antigen processing cross presentation	0.5080638059003476	3.2722728561029863	0.0010668655998755	0.7712659528728926	0.0141770024906541	49	P51665,Q13200,P62333,P43686,Q9UNM6,O00161,P28070,O00232,P09429,O75832,P62195,Q99460,P48556,Q99436,O15111,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	37
Ub specific processing proteases	0.5067996288656578	3.236293796609111	0.0012109268012947	0.8126009355809497	0.015787743767824	74	P51665,P54578,Q13200,P62333,Q9UNM6,P43686,P28070,P62191,O00232,O75832,P62195,Q99460,P48556,Q99436,Q9Y265,Q86UV5,P25787,Q96RU2,P61289,Q12933,P20618,O00233,Q14694,O94966,Q13309,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q15008,P25788,Q96K76,Q9NZL9,Q96FW1,P28066,Q9UPT9,P17980,Q16186,Q06323,P25786,Q9UPU5,Q9UL46,P14735,Q13485,P49720,O00231,P45974	53
Cyclin d associated events in g1	0.7290548499321071	3.2109813553532827	0.0013228251713861	0.8394828698108437	0.0170854615593987	13	P63208,Q00534,P30154,P42771,P11802,P12931,P06400,Q13616,Q13309,P63151	10
S phase	0.4876475094488491	3.2008380021441702	0.0013702854869679	0.8496866566369753	0.0175345791017563	97	P51665,O00231,Q13200,P62333,P43686,Q9UNM6,P28070,P12004,O00232,O75832,P62195,Q99460,P48556,Q99436,Q15054,P35244,P25787,Q9BRT9,P06400,P61289,P09884,Q13616,P49643,P20618,O00233,P49642,Q13309,P35998,P35250,O43929,O43242,O00487,Q9BRX5,P25789,P39748,Q92530,P11802,P49721,P28340,P28074,P55036,P40937,P63208,Q15008,P25788,P28072,P27694,P17980,Q06323,P28066,P25786,Q9UL46,Q7Z5K2,P49720,P33991,P49736	56
Vesicle mediated transport	0.3122727096792734	3.197693280934628	0.0013853154034921	0.8527808830972898	0.0175642741984054	240	Q9Y5X3,Q9UJY4,P61163,P59998,P27348,Q99816,P40616,P50395,P47755,Q5H9R7,Q9BXS5,Q86SZ2,Q9BXI6,P42566,Q14247,Q9NVG8,Q14204,O43747,O43264,P53618,Q96JB2,P54646,P61020,Q8WUX9,P50570,P48444,P47756,Q99627,O15027,Q9BUF5,Q9NP79,Q15363,P84085,Q9Y496,Q96KP1,O15260,P60520,P61201,P62258,Q9NQT8,Q92598,Q92538,Q9NZ32,Q9BZE9,Q9Y6G9,O43237,Q96D71,P51148,P31946,Q13492,Q9Y5X1,O00471,Q99961,Q9UNS2,P11142,O60664,Q4KMP7,Q13561,P68371,Q8N6T3,O00161,Q7L5N1,P33908,P04350,Q9H0H5,Q9Y6I3,Q13885,P22681,P52594,P52907,O14976,O15498,P12931,P68402,Q9NVZ3,O00401,Q8IUR0,Q15642,O95486,Q15436,P61160,Q8TC07,Q9UN37,Q9BT78,Q7Z6M1,O00743,O15145,P35606,O00443,Q15102,Q14203,P62330,Q07866,Q9Y678,Q9UID3,Q92905,Q9H0V9,Q12955,P20336,O15144,O95239,O60343,P18085,Q04917,P35579,Q86VN1,Q14C86,Q7Z392,O75935,O60645,Q9UBF2,Q10471	112
Cytokine signaling in immune system	0.2981384554348055	3.1944494492965823	0.0014009781822275	0.8559376906447939	0.0176013804348947	181	Q13126,P43686,P28070,P17987,P40222,P26038,P48556,Q53EL6,Q16539,P78417,Q14258,P46109,O43242,P25788,Q99439,Q06323,Q9UL46,Q15369,Q13200,P62333,Q06124,O15111,Q02750,P25787,P61289,P35998,Q07820,P30153,P30154,P25789,Q92530,P49721,Q9Y3Z3,P17980,P11142,P25786,Q13325,P51665,P40763,O00232,P05388,P09429,Q9UII4,P61088,P52907,P22681,O43432,P29372,P20618,P41240,P61221,O00487,P28074,Q13177,Q15008,Q14240,Q93034,P14174,P49720,O00231,P42224,Q8TBC4,P60842,P51452,Q9UNM6,O75832,P62195,Q99460,Q12899,Q99436,P06730,Q13616,Q12933,O00233,P63208,P28072,P60900,P55036,P61081,P37837,Q16658,Q15370,Q14974,P28066	84
Phase ii conjugation of compounds	0.5210540855175012	3.188689714692321	0.0014291919428324	0.8614544380992513	0.017667451781456	32	Q99707,Q9UI30,Q9NZL9,P48637,O60701,Q9Y5N5,Q96IU4,P78417,P21266,O95340,O43252,Q8WUX2,Q96KP4,P28161	14
Signaling by notch	0.4995988499152759	3.151984038023018	0.0016216513788624	0.893854165365045	0.0196589667156839	58	P51665,Q9H488,Q13200,P62333,Q9UNM6,P43686,P28070,P62805,P62191,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,Q9HCE1,P61289,Q13616,P20618,O00233,Q15398,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,Q15008,Q9Y6A5,P25788,P28066,P17980,Q06323,P25786,Q9UL46,Q04726,P49720,O00231,P42224	45
Cilium assembly	0.4964102394742065	3.1278877144071706	0.0017606743069595	0.9124369778669184	0.0209763094156737	55	P50991,O94927,P62258,P61163,Q92538,P17987,Q14203,P04350,P49368,Q9H0F7,Q15691,Q13885,P07437,Q9BW83,P48643,P18085,P30153,P36405,P50990,Q96CS2,O00471,Q8NCM8,Q8IW35,Q9H6D7,O75935,Q9Y547,Q9BUF5,O60645,Q92973,Q9Y496,Q96KP1,Q13561,P78371,P68371	34
Deubiquitination	0.483230323025056	3.1027442386894184	0.0019173526364228	0.9295128515953552	0.0226477037909097	93	P51665,P54578,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q15018,Q99436,P38398,Q9Y265,Q86UV5,P25787,Q96RU2,P61289,Q12933,P20618,O00233,Q14258,O94966,Q13309,P35998,O43242,O00487,P25789,Q92530,P28074,P28072,P49721,P60900,P55036,P85037,Q15008,Q9NXR7,P25788,Q96K76,Q6GQQ9,Q9Y5K5,Q9NZL9,Q96FW1,Q9NWV8,P17980,Q06323,P28066,Q9UPT9,Q16186,P25786,Q9UL46,Q9UPU5,P14735,P49720,O00231,P45974	58
Beta catenin independent wnt signaling	0.4937006708996687	3.08833389354521	0.0020128218179724	0.9382414633626978	0.0234510111002878	59	P51665,Q08209,Q13200,P62333,Q9UNM6,P43686,P28070,Q01970,P62191,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,Q9HCE1,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,P49721,P60900,O43242,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	39
Copi independent golgi to er retrograde traffic	0.5477709703676964	3.087379185714501	0.002019298350893	0.9387928776350964	0.0234510111002878	26	Q9Y6G9,O75935,Q9BUF5,Q13885,P52907,O43237,P61163,Q15102,Q10471,P68371,Q14203,P04350,Q9NZ32,Q14204,Q13561,P68402,P47755	17
G2 m checkpoints	0.4883483129759479	3.0773870365331906	0.0020882397029109	0.9443662220886804	0.0240495605785243	83	P51665,O00231,P62805,Q13200,P62333,P43686,Q9UNM6,P28070,P62258,O00232,Q9UQ84,P27348,O75832,P62195,Q99460,P48556,Q99436,P38398,Q92547,P61088,P35244,P25787,P61289,P20618,O00233,P35998,P31946,O43929,O43242,O00487,P25789,Q92530,P28074,P35250,P49721,P28072,Q04917,P60900,P55036,P40937,Q15008,Q9NXR7,P25788,P33992,Q9NWV8,P27694,P17980,Q06323,P14635,P28066,P25786,Q9UL46,O14757,P49720,P33991,P49736	56
Mapk family signaling cascades	0.469210014658992	2.992696765563455	0.0027652434893135	0.9782221100002058	0.0305725320178501	98	P51665,P53041,Q13200,P62333,P43686,P46940,P28070,Q9UNM6,Q96P70,O00232,Q16512,O75832,P62195,P21359,P48556,Q99460,Q99436,Q06124,Q02750,P25787,P12931,P61289,P10398,P20618,O00233,P41240,P25685,P35998,P30153,P31946,O14980,O43242,P30154,P25789,Q92530,O00487,P28074,P49721,P28072,P55036,Q13177,Q15008,P25788,P17980,Q06323,P28066,P25786,Q9UL46,P30086,P49720,O00231,Q05397,Q99956	53
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s	0.4815856103943463	2.987419536720999	0.0028134334341596	0.979629038197097	0.0306154724882567	52	O15372,P05198,P41091,Q7L2H7,P46782,P62847,P61247,Q04637,P62244,P62851,O00303,P06730,Q9Y262,P15880,P62081,P46781,P08865,O75822,P08708,P62701,P62753,Q14240,P62277,P60228,P62861,P62841,P62269,Q9UBQ5,P62854,P23396,P60842	31
Class i mhc mediated antigen processing presentation	0.4266370818443793	2.886035367676924	0.0039012831368003	0.9954929739509288	0.0396439212871921	123	P51665,Q9NZ08,P52888,Q13200,P62333,Q8TDB6,P43686,P28070,O00161,Q9UNM6,Q7Z7E8,Q96ME1,O00232,Q5VTB9,P09429,O75832,P62195,Q99460,P48556,Q99436,P61086,Q9UII4,P61088,Q92990,Q8IWV7,P22314,O15111,P25787,P61289,Q13616,Q5T447,P20618,O00233,Q13309,P35998,P63208,O43242,O00487,P25789,Q92530,P28074,P28072,Q7Z6Z7,P49721,O95376,P68036,O95352,Q15386,Q05086,O95486,P55036,Q15436,P61081,Q15008,P25788,Q93034,P60900,Q15370,Q9C0C9,P17980,Q06323,P28066,P25786,Q9UL46,Q15369,P55786,P49720,O00231,Q8TBC4,A0AVT1	70
Cytosolic trna aminoacylation	0.5427362291387111	2.871694970371997	0.0040827684228801	0.9964962998574354	0.0409434786288916	23	O43776,Q13155,Q9NSD9,Q15181,P23381,Q9P2J5,Q9Y285,P49589,P54577,P41252,P14868,P54136,O43324,P26640,P26639,P41250,P49591	17
Lagging strand synthesis	0.5898187872998517	2.871257558128713	0.0040884226127257	0.996523682836302	0.0409434786288916	19	Q15054,P39748,P27694,P35244,P40937,P09884,P12004,P49643,P49642,P35250	10
E2f mediated regulation of dna replication	0.688693731640105	2.8609153643327656	0.004224198045255	0.99712069585935	0.0416988692753038	12	O43929,P30154,P09884,P06400,P49643,P49642,P30153	7
Cooperation of prefoldin and tric cct in actin and tubulin folding	0.630429135893762	2.8355029303416437	0.0045753595334367	0.998231558245938	0.0445292033465468	16	Q99471,P61758,Q9BUF5,P50991,Q13885,P40227,Q99832,P50990,P17987,P48643,P04350,P78371,P68371	13
Formation of tubulin folding intermediates by cct tric	0.6769662921348389	2.7918908361096317	0.0052401031354119	0.9992974985037378	0.0496015241995838	12	Q9BUF5,P50991,Q13885,P40227,Q99832,P50990,P17987,P48643,P04350,P78371,P68371	11
Signaling by interleukins	0.4393577209010946	2.7605500067845075	0.0057704123154176	0.9996638010296764	0.0531647321327145	108	Q13126,P51665,P51452,Q13200,P62333,P43686,P40763,P28070,Q9UNM6,O00232,P17987,P05388,P40222,P26038,P09429,O75832,P62195,Q99460,P48556,Q99436,Q53EL6,P61088,Q06124,P52907,O15111,Q02750,P25787,Q16539,P22681,P61289,Q13616,P78417,P20618,O00233,P46109,P35998,Q07820,P30153,P63208,O43242,P30154,P25789,Q92530,O00487,P28074,P49721,P28072,P60900,P55036,P37837,Q13177,Q15008,P25788,Q99439,P17980,Q06323,P28066,P11142,P25786,Q9UL46,P14174,P49720,O00231,P42224	64
Toll like receptor 9 tlr9 cascade	0.5893225708373757	2.7572954212848693	0.0058281670019537	0.9996897369147542	0.0532627968002166	18	P63208,P30154,P61088,O15111,Q02750,Q16539,Q13616,P09429	8
Egfr downregulation	0.8669486353684324	2.7312006376487017	0.0063104041589459	0.9998413184680306	0.0562643777268596	6	P42566,Q9Y6I3,Q99961	3
Netrin 1 signaling	0.664084428424648	2.715456210340953	0.0066184528403032	0.9998966205701084	0.0582592472948988	12	Q06124,O00401,P15311,P12931,Q16539,P16333,Q16512	7
Toll like receptor cascades	0.5053437237986718	2.6910489025960147	0.007122775304408	0.9999487553829584	0.0615229716918248	25	P63208,P30154,P61088,Q06124,Q6SZW1,O15111,Q02750,Q16539,Q13616,P09429	10
Toll like receptor tlr1 tlr2 cascade	0.6067055991702964	2.6791593264859856	0.0073807265271947	0.9999642153891354	0.0633550562769143	16	P63208,P30154,P61088,O15111,Q02750,Q16539,Q13616,P09429	8
Interleukin 17 signaling	0.6217527823468125	2.676128381056433	0.0074478109976228	0.9999674064413356	0.0635362641895971	14	P63208,P30154,P61088,O15111,Q02750,Q16539,Q13616,P30153	8
Telomere c strand lagging strand synthesis	0.5123975283207437	2.6271685539470404	0.0086098673953349	0.9999935430686412	0.0729989984070732	23	Q15054,P39748,Q8WVB6,P27694,P35244,P40937,P09884,P12004,P49643,P49642,P35250	11
Translesion synthesis by polk	0.703156834254073	2.6157626284712703	0.0089028425568065	0.9999957082876052	0.0747222544954015	9	P35250,P27694,P35244,P40937	4
Tp53 regulates transcription of cell death genes	0.7884160400764431	2.597139141862422	0.0094003835967861	0.9999978558712423	0.0771849364816876	7	P55212,P42575	2
Recruitment of mitotic centrosome proteins and complexes	0.4688666788449713	2.592827126887006	0.0095190605284574	0.9999981830569316	0.0771849364816876	30	O94927,P62258,P61163,Q7Z460,P17612,Q14203,P04350,Q9BSJ2,Q15691,P07437,P07900,P21127,Q14204,P43034,P30153,P61981,Q14008,Q96CS2,Q96CW5,Q9H6D7,O75935,Q13561,P68371	23
Apoptosis	0.4412131117519119	2.5856542358281276	0.0097194376684948	0.9999986262494855	0.0776431379067042	91	P51665,P55212,Q9UJU6,Q13200,P62333,P43686,P40763,P28070,P62258,Q9UNM6,O00232,P09429,P27348,O75832,P62195,Q99460,P48556,Q99436,P25787,O00273,P61289,O76075,P15924,P20618,Q12933,P26583,Q9UDY2,O00233,P35998,P31946,O14727,O43242,P25789,Q92530,P42771,O00487,P49721,P28074,P28072,Q04917,P55036,Q9UKG1,Q13177,Q15008,P30419,P25788,P17980,Q06323,P28066,Q13464,P25786,Q9UL46,O00429,P55210,P49720,O00231,Q05397	57
Rab regulation of trafficking	0.4295907027748364	2.5780790952991803	0.0099351253919734	0.9999989833572542	0.0784591045240421	36	P60520,Q8IUR0,P62258,Q9UJY4,Q9BXI6,Q86SZ2,P20336,Q8TC07,Q4KMP7,P62330,Q9NVG8,P51148,P50395,Q7Z392	14
Developmental biology	0.2919738020783578	2.573318953573081	0.0100728331791206	0.9999991611551456	0.079094633258777	275	O14786,P61247,P62847,P28070,P43686,Q04637,P62244,P62191,P62750,P59998,P26038,Q16512,P48556,Q14195,Q96EK7,Q96S59,P42766,Q16539,P62899,Q9Y490,P08238,P62081,Q00535,O43242,O14818,O14531,P08708,P11802,P47914,P18124,P62701,P61353,P25788,P62841,P62269,Q9BUF5,Q06323,Q9UL46,Q15369,P62495,P62805,Q13200,P62333,Q9H944,Q06124,Q02750,P25787,P61289,P35998,P25789,Q92530,P49721,Q9Y3U8,P17980,P15311,P11142,O75122,P25786,P15170,P68371,P62854,P62906,Q05397,P51665,P46939,P40763,P46782,Q86X55,O00232,P05388,P04350,Q13885,P12931,P19784,P15924,Q71SY5,P20618,P46781,O00487,P28074,O00401,Q13177,Q15008,P61160,P62277,P62861,Q9BPU6,O60271,O15145,P49720,O00231,Q9UNM6,Q96P70,P16333,O75832,P62195,Q99460,Q99436,Q16555,Q08554,Q12955,P15880,O00233,O15144,O95239,P08865,P28072,P46778,P62910,P55036,P60900,Q92600,P35579,Q7Z406,Q15370,P28066,P84098,Q13464,Q13485,P23396	120
Processive synthesis on the lagging strand	0.603210636098529	2.557029276062736	0.0105570332189042	0.9999995733828628	0.0819652803849754	14	Q15054,P39748,P27694,P35244,P09884,P12004,P49643,P49642	8
Methylation	0.6898546811356234	2.542583124429377	0.0110036424416883	0.999999771406176	0.0844835214134075	9	Q99707,Q9UI30,Q9Y5N5,P78417	4
Regulation of plk1 activity at g2 m transition	0.4322959940327548	2.5355201537427656	0.0112280467505003	0.9999998329431946	0.0852915806914543	35	O94927,P62258,P61163,Q7Z460,P17612,Q14203,P04350,Q15691,P07437,Q13616,P07900,Q14204,P43034,P30153,P63208,P61981,Q14008,Q96CS2,Q9H6D7,O75935,O14965,P14635,P06493,Q13561,P68371	25
Post chaperonin tubulin folding pathway	0.6876186553737181	2.530223845047239	0.0113989777696827	0.9999998684477512	0.0860840834847083	9	Q9BUF5,Q15813,Q13885,Q99426,P68371,P04350	6
Translocation of slc2a4 glut4 to the plasma membrane	0.4360121428422867	2.5070755842154746	0.0121734677201619	0.9999999554642094	0.0914333282025205	34	Q04917,Q9BUF5,O60645,O00161,P62258,Q9Y496,P54646,Q96KP1,P27348,P68371,P04350,O00471,O60343,Q9BZE9,P31946	15
Biological oxidations	0.4333802688156844	2.498438522431116	0.0124741777087802	0.999999970760326	0.0925662573943773	49	Q99707,Q9UI30,P07099,P48637,O60701,O43488,Q9Y5N5,Q96DG6,Q96IU4,P11766,P78417,P21266,O95340,Q8WUX2,Q96KP4,P28161	16
Intraflagellar transport	0.6441975756375078	2.4969900781992056	0.0125252461163158	0.9999999727771528	0.0925662573943773	11	Q9BUF5,Q13885,Q9BW83,Q9Y496,P68371,P04350,Q9Y547,Q8NCM8	8
Signaling by wnt	0.4337662024681757	2.4887169752865836	0.0128204980733541	0.9999999819926322	0.0941094456903489	90	P51665,Q08209,P62805,Q13200,P62333,P43686,Q9UNM6,P28070,Q01970,P62191,O00232,O75832,P62195,Q99460,P48556,Q99436,Q9Y265,Q9HCK8,P25787,P19784,Q9HCE1,P61289,Q13616,P20618,O00233,O75436,P35998,P30153,O14980,O43242,P30154,P25789,Q92530,O00487,P28074,P49721,P28072,P63208,P60900,P55036,Q15008,P25788,Q96QK1,P17980,Q06323,P28066,P25786,Q9UL46,Q04726,P49720,O00231	51
Anchoring of the basal body to the plasma membrane	0.4563916223539747	2.476900368045686	0.0132528891537251	0.9999999901711362	0.095338636171295	30	O94927,P62258,P61163,Q7Z460,P17612,Q14203,P04350,Q15691,P07437,P07900,Q14204,P43034,P30153,P61981,Q14008,Q96CS2,Q8IW35,Q9H6D7,O75935,Q13561,P68371	21
Activation of the pre replicative complex	0.5123196809100146	2.475264071669365	0.0133137693720624	0.9999999909744972	0.095338636171295	21	O43929,P27694,P35244,P09884,P49643,P33991,P49736	7
Cargo recognition for clathrin mediated endocytosis	0.4448440955818859	2.4737041446566637	0.0133720382239959	0.9999999916818684	0.095338636171295	32	Q9Y6I3,Q99627,Q9UNS2,P22681,P52594,Q92905,Q13492,Q96D71,P42566,Q99961,Q9NVZ3	11
Regulation of mrna stability by proteins that bind au rich elements	0.4377583780432154	2.473403832940092	0.0133832817780255	0.9999999918118466	0.095338636171295	65	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,Q04637,O00232,O75832,P62195,Q99460,P48556,Q99436,Q8IZH2,P25787,Q16539,P61289,P20618,O00233,P35998,P31946,O14980,P28072,O00487,P25789,P28074,Q92530,P55036,O43242,P49721,P60900,P39687,Q15008,P25788,Q9Y2L1,P28066,P17980,Q06323,P11142,Q92973,P25786,Q9UL46,P49720,O00231	44
Neutrophil degranulation	0.2892529838054346	2.4499409747554832	0.0142879634492634	0.9999999976954688	0.1007447218718471	171	P51665,Q9NQR4,Q9UJU6,P53990,Q13200,P46940,Q9UNM6,O00161,P04075,P06744,Q96G03,O00764,O00232,P09429,P31949,Q9NZ32,Q99460,Q9P000,P50395,Q99436,Q9Y6G9,P25787,P07437,Q16539,Q9Y315,O75874,Q08554,P12268,P20336,P15924,P20618,P51148,P68402,P35998,O14727,O43242,O00487,Q9UBI1,P30041,Q7Z6Z7,P13639,P13798,O95352,P04080,P53618,P50990,Q15008,P61160,Q99439,Q92820,O60610,Q9BRF8,P17858,P20839,P17980,P28066,Q13464,P11142,P07741,P35237,P13010,P78371,P09972,P14174,O15260,P36871,P09960,P68371,P18669,O00231	70
Activation of atr in response to replication stress	0.5455585163302425	2.446022307225812	0.0144442063330116	0.9999999981488586	0.1008176421829401	18	O43929,P27694,P35244,P35249,P40937,P25205,P15927,O14757,P33992,P33991,P49736,P35250	12
Inhibition of replication initiation of damaged dna by rb1 e2f1	0.7557968971624676	2.438069046315914	0.014765953321445	0.9999999988211286	0.1025454647750605	7	P30154,P09884,P06400,P49643,P49642	5
Signaling by egfr	0.6152087988064213	2.419555491264608	0.0155394895768672	0.9999999996018464	0.1071994132008937	12	P42566,Q9Y6I3,Q99961,P22681	4
Pentose phosphate pathway	0.6537158044364484	2.41531667849142	0.0157215342591972	0.9999999996916432	0.1071994132008937	10	O95336,P49247,Q9Y315,P37837,P29401,Q96G03,P52209,P11908	8
Folding of actin by cct tric	0.6761221945137198	2.394931003312033	0.0166234930963895	0.9999999999131434	0.1109839007691321	8	P50991,P40227,Q99832,P50990,P17987,P48643,P78371	7
Nucleotide biosynthesis	0.5934909897016204	2.3855006579124236	0.0170558918727348	0.999999999952703	0.1127810649192321	13	P30520,P20839,P22102,P31939,P12268,P49915,O76075,P11172,P22234	9
Gene and protein expression by jak stat signaling after interleukin 12 stimulation	0.4687831632635934	2.377658314039254	0.0174229621157528	0.9999999999717736	0.1146596840189071	25	Q13126,P52907,Q9UL46,P17987,P05388,P78417,P14174,Q99439,Q53EL6	9
Formation of incision complex in gg ner	0.5603571510531555	2.3662519829049047	0.0179692094986179	0.9999999999869114	0.117694064109431	16	P18074,Q86WJ1,P61088,P27694,P62877,P35244,Q92759,Q9UGN5,Q13619,Q16531	10
Mismatch repair	0.589878276508525	2.3624733080254665	0.0181534486565007	0.999999999989901	0.1180355051859187	13	Q15054,P27694,P35244,P12004,Q9UQ84,P43246,P52701	7
Translesion synthesis by polh	0.6031176001317826	2.3449180497694626	0.0190312620790131	0.999999999997066	0.1210974387034033	12	P35250,P27694,P35244,P40937	4
Cargo trafficking to the periciliary membrane	0.53128611654705	2.3424285524564263	0.0191587018187213	0.9999999999975484	0.1210974387034033	18	P36405,Q9H0F7,O60645,P50990,Q96KP1,P17987,Q92538,P48643,P78371,P18085,O00471	11
Costimulation by the cd28 family	0.5637937539813886	2.341868128502394	0.0191874931066737	0.9999999999976458	0.1210974387034033	15	P30154,Q06124,P12931,Q16512,P41240,P30153	6
Protein ubiquitination	0.4583341844633938	2.3216884607540345	0.0202497167367257	0.9999999999994734	0.1249335202239059	26	P61088,Q14527,P68036,P50542,P12004,Q96BN8,Q9GZS3,P61086,P45974,A0AVT1	10
Cell cycle mitotic	0.27716256701774	2.319235143562468	0.0203822898912635	0.9999999999995632	0.1251925539098944	254	P43686,P28070,P12004,P31350,P48556,P63151,P35244,Q9BRT9,Q9Y570,Q13309,O43929,O14980,O43242,Q9BRX5,P11802,Q96CS2,P25788,Q9H8Y8,Q96CW5,Q8WUX9,Q14739,Q9BUF5,Q06323,Q9UL46,O60566,P49736,P53990,P62805,Q13200,P62333,P62258,Q8TD19,Q9Y6G9,Q15691,P25787,O43237,P04183,P06400,P61289,P49642,P35998,P30153,Q00534,P30154,P25789,P39748,P42771,Q92530,P49721,Q15003,Q15021,Q92674,Q96EA4,P17980,P14635,O75122,P25786,Q13561,P68371,P51665,O94927,Q8NC56,O00232,P04350,Q96GX5,Q9HC35,Q15054,Q13885,P07437,P12931,P19784,P09884,P49643,Q99986,P20618,P21127,Q9P258,O00487,P28340,P28074,Q15008,Q9UN37,P49720,P33991,Q9UNM6,O75832,P62195,Q2NKX8,Q86XI2,Q13616,O00233,P35250,P63208,P55036,P40937,O75935,P27694,P28066,Q7Z5K2	99
Ephb mediated forward signaling	0.5126846704703605	2.3041198654465833	0.0212159158933811	0.9999999999998652	0.128036662727741	19	O00401,Q13464,Q05397,Q92747,P12931,O15143,O15145,P59998,P61160,Q16512,O15144,P23528	12
Clathrin mediated endocytosis	0.4191056018452798	2.300310186435652	0.0214306529850618	0.9999999999999004	0.1287702714145891	56	Q8N6T3,P61201,Q7L5N1,O00443,P59998,P62330,P20339,Q9Y6I3,P22681,P52594,Q92905,O14976,Q96D71,P42566,O15144,Q14247,P51148,Q9NVZ3,O00401,Q13492,Q9Y5X1,Q15642,P61020,P61160,P50570,Q14C86,Q99627,Q99961,Q9UNS2,Q9BT78,P11142,Q92747,O15145	33
Metabolism of nucleotides	0.4136099799021079	2.2935147912758533	0.0218183847848236	0.9999999999999424	0.1297861646493729	48	Q06203,P30085,Q9Y3D8,P15531,P31350,P23919,P22102,Q96DE0,Q9BY32,P04183,Q9P2T1,P12268,O15067,O76075,P11172,P23921,Q9NRF8,P27708,P00568,P30520,P00492,Q16881,P31939,P49915,P32321,Q9Y3Z3,Q9H773,P20839,P07741,O43598,P49902,P17812,Q9UKK9,Q9BZX2,P33316,P22234	36
Bbsome mediated cargo targeting to cilium	0.6575254681498104	2.2924193063211526	0.0218814590183096	0.9999999999999474	0.1297861646493729	8	Q9H0F7,P50991,P50990,P17987,P48643,P78371	6
Tp53 regulates transcription of caspase activators and caspases	0.8970357872432819	2.2777740272275717	0.0227400445486898	0.9999999999999843	0.1329831565744641	4	P55212,P42575	2
Signaling by ntrks	0.4290222982040057	2.2671987304593735	0.0233780883578988	0.9999999999999936	0.1332172395097788	31	P30154,Q06124,P40763,Q02750,P12931,Q16539,P46109,Q00535,P31946	9
Recruitment of numa to mitotic centrosomes	0.4228036876556275	2.2584781250507984	0.0239158668607999	0.999999999999997	0.1332172395097788	32	O94927,P62258,P61163,Q7Z460,P17612,Q14203,P04350,Q9BSJ2,Q15691,Q13885,P07437,P07900,Q14204,P43034,P30153,Q14008,Q96CS2,Q96CW5,Q9H6D7,O75935,Q9BUF5,Q13561,P68371	23
Resolution of ap sites via the multiple nucleotide patch replacement pathway	0.4584860426944493	2.2555725260366604	0.0240974154408555	0.9999999999999976	0.1332172395097788	24	P39748,P27694,P40937,P35244,Q86W56,P27695,P35250	7
Diseases of signal transduction by growth factor receptors and second messengers	0.3344477006891521	2.254018139250466	0.02419502685742	0.999999999999998	0.1332172395097788	149	P51665,Q13200,P62333,P43686,P40763,P28070,Q92614,P46940,Q9UNM6,O00232,P26038,Q14203,O75832,P62195,P21359,P48556,Q9NRY5,Q9HC35,Q99460,Q99436,Q07866,Q06124,P22681,O15111,Q02750,P25787,P12931,P61289,P49589,P13984,P10398,P26641,P20618,Q13616,O00233,P41240,O43252,Q96B36,P35998,P30153,P31946,P63208,O43242,P30154,P25789,Q92530,O00487,P28074,P49721,P28072,P60900,P55036,O95352,P31939,Q15008,P25788,P17980,Q9NR09,Q06323,P62942,P28066,P25786,Q9UL46,P30086,Q86WB0,P49720,O00231,P42224,Q99956	69
Dna damage bypass	0.4317545254489765	2.2446916367590046	0.0247879353124291	0.9999999999999992	0.1356609853589059	30	Q15054,P28340,P27694,P62877,P35244,P40937,P35249,O94782,P12004,Q07864,P55072,Q14694,Q13619,Q9NZJ0,Q8TAT6,Q14258,Q16531,P35250	18
Programmed cell death	0.4058968881194874	2.2411553785884166	0.0250160120749554	0.9999999999999992	0.1356609853589059	101	P51665,P55212,Q9UJU6,Q13200,P62333,P43686,P40763,P28070,P62258,Q9UNM6,O00232,P09429,P27348,O75832,P62195,P48556,P25787,O00273,P61289,O76075,P15924,P20618,Q12933,P26583,Q9UDY2,O00233,P35998,P31946,O14727,O43242,P25789,Q92530,P42771,O00487,P49721,P28074,Q04917,P55036,Q9UKG1,Q13177,P30419,P25788,Q8WUX9,P17980,Q06323,P28066,Q13464,P25786,Q9UL46,O00429,P55210,P49720,Q05397	53
Rho gtpases activate wasps and waves	0.4905780280879226	2.2393217526868097	0.025134988509845	0.9999999999999994	0.1356609853589059	20	Q9UQB8,O00401,Q92747,Q9Y6W5,P59998,P16333,P61160,O15144,O15145,Q05397	10
Sulfur amino acid metabolism	0.6346203046807954	2.232405104111775	0.0255882007807568	0.9999999999999998	0.1368265101927335	9	Q13126,Q9BV20	2
Polymerase switching	0.5536794318613862	2.2315821134427196	0.0256425948914023	0.9999999999999998	0.1368265101927335	14	Q15054,P40937,P09884,P12004,P49643,P49642,P35250	7
Intrinsic pathway for apoptosis	0.5271630696496227	2.220316567290689	0.0263972860932515	1.0	0.1390487036528233	17	O14727,Q04917,P42771,P40763,P62258,P30419,P27348,P31946	8
Dual incision in gg ner	0.4422034834842504	2.2144169145853443	0.0268001123967267	1.0	0.1398791952828093	27	P18074,Q15054,Q86WJ1,P28340,P62877,P35244,P40937,P35249,Q92759,P27694,P12004,Q07864,Q9UGN5,Q13619,Q16531,P35250	16
Purine ribonucleoside monophosphate biosynthesis	0.6171341624869013	2.203125632186263	0.0275858950410348	1.0	0.1417238176457625	10	P30520,P20839,P22102,P31939,P12268,P49915,P22234	7
Inositol phosphate metabolism	0.6271115815780285	2.189463193741556	0.0285631909086467	1.0	0.1456190803592103	9	Q13572,Q9NPH2,Q92551	3
Interleukin 12 family signaling	0.4256842498175298	2.18685077494518	0.0287534194205121	1.0	0.1456190803592103	30	Q13126,P52907,P40763,Q9UL46,P05388,P78417,Q99439,Q53EL6	8
Glutathione conjugation	0.5409183462911866	2.1866845037340696	0.0287655636310162	1.0	0.1456190803592103	15	P48637,P78417,P21266,Q8WUX2,P28161	5
Pcna dependent long patch base excision repair	0.4824186967177529	2.17505547898284	0.0296259591922671	1.0	0.14888391128623	20	Q15054,P39748,P27694,P35244,P40937,P12004,P27695,P35250	8
Global genome nucleotide excision repair gg ner	0.3992975989518884	2.164279775958614	0.030442883902193	1.0	0.1518847131871149	45	Q9Y265,Q15054,P61088,Q86WJ1,P28340,P35244,P61201,Q92905,P40937,Q92759,Q9UNS2,P27694,Q7L5N1,P12004,Q13619,Q99627,P35250	17
Protein folding	0.4076516808447666	2.161823524109223	0.030631781523168	1.0	0.1522774175000655	33	Q99471,P50991,P40763,P17987,Q99426,P04350,P61758,Q15813,Q13885,Q15477,Q9BTW9,P19784,P48643,P40227,P50990,Q9Y2T2,Q9BUF5,Q99832,P78371,P68371,Q9BUR4	21
Unwinding of dna	0.6325042965336941	2.152762650660108	0.0313373368679004	1.0	0.1544388147922768	8	P33991,Q9BRX5,Q9BRT9	3
Eukaryotic translation initiation	0.3988823850717673	2.1519433806438175	0.0314018140062444	1.0	0.1544388147922768	101	O15372,P05198,P41091,Q7L2H7,P61247,P62847,P46782,Q04637,P62244,P62750,P05388,P62851,O00303,Q9NR50,P55010,P42766,P06730,P62899,Q9Y262,P15880,P62081,P46781,P08865,P46778,O75822,P62910,P08708,P47914,P18124,P62701,P49770,P61353,P62753,P61927,P60228,P62277,Q9Y3U8,Q14240,P62861,P62841,P62269,Q14232,P84098,Q9UBQ5,Q13144,P62854,P62906,P23396,P60842	49
Negative regulation of fgfr1 signaling	0.6962537549582303	2.1404500519858147	0.0323184132548273	1.0	0.156167996916683	7	P12931,P30153,Q06124,P22681	4
Negative regulation of fgfr2 signaling	0.6962537549582303	2.1404500519858147	0.0323184132548273	1.0	0.156167996916683	7	P12931,P30153,Q06124,P22681	4
Negative regulation of fgfr3 signaling	0.6962537549582303	2.1404500519858147	0.0323184132548273	1.0	0.156167996916683	7	P12931,P30153,Q06124,P22681	4
Negative regulation of fgfr4 signaling	0.6962537549582303	2.1404500519858147	0.0323184132548273	1.0	0.156167996916683	7	P12931,P30153,Q06124,P22681	4
Spry regulation of fgf signaling	0.6962537549582303	2.1404500519858147	0.0323184132548273	1.0	0.156167996916683	7	P12931,P30153,Q06124,P22681	4
Heme biosynthesis	0.7785131114499211	2.1284619127589	0.0332988045886968	1.0	0.1592351139847025	5	P08397,P06132	2
Interleukin 12 signaling	0.4315262067739104	2.1171832297412654	0.0342443001203585	1.0	0.1620740505696419	27	Q13126,P52907,Q9UL46,P17987,P05388,P78417,P14174,Q99439,Q53EL6	9
Eukaryotic translation elongation	0.4062260056945728	2.1100260775728215	0.0348561097496575	1.0	0.1644066336997501	77	P61247,P62847,P46782,P62244,P62750,Q05639,P05388,P42766,P62899,P26641,P15880,P62081,P46781,P08865,P29692,P46778,P62910,P08708,P13639,P47914,P18124,P62701,P62277,P62861,Q9Y3U8,P62841,P62269,P84098,P24534,P62854,P62906,P23396	32
Downstream signal transduction	0.6116530849427203	2.1004903723846007	0.0356857266487393	1.0	0.1666137642856682	9	Q06124,P40763,P12931,P16333,P46109	5
Signaling by pdgf	0.6116530849427203	2.1004903723846007	0.0356857266487393	1.0	0.1666137642856682	9	Q06124,P40763,P12931,P16333,P46109	5
Traf6 mediated nf kb activation	0.7705106168767261	2.0920560689774197	0.036433500360985	1.0	0.1689634144257762	5	Q14258,P09429,Q12933	3
Dcc mediated attractive signaling	0.7279846859903377	2.0876219926171937	0.0368319465400126	1.0	0.1702399669508277	6	P12931,P16333,O00401	3
Hsf1 activation	0.5319235967822789	2.085390932674099	0.0370338292319809	1.0	0.1706025066619922	14	P0DMV9,P27694,P35244,P62258,Q92598,P15927,Q02790,Q15185,P55072,P25685,P08238	11
Tnf signaling	0.6826939023902047	2.0713925621438753	0.0383221254135355	1.0	0.1742143990839016	7	Q96BN8,Q6GQQ9,Q12933	3
Recycling pathway of l1	0.469068803722879	2.069189236352477	0.0385283323745373	1.0	0.1745775584970839	20	Q9BUF5,Q13885,P15311,P12931,O95239,P26038,P09496,P50570,P04350,P68371,Q16555,P35241	12
Platelet sensitization by ldl	0.7233587718471712	2.0654325806250298	0.0388820885063772	1.0	0.1750327241557436	6	P30154,Q16539,Q06124	3
Activation of ampk downstream of nmdars	0.6785838965181507	2.050370539326347	0.0403282858185529	1.0	0.1803622022599145	7	P54646,P68371,Q9BUF5,P04350	4
Selective autophagy	0.4057259510870857	2.040401442046498	0.041310358402633	1.0	0.1833111861231731	31	Q9Y6G9,Q9BUF5,P61088,P50542,O43237,P12931,P19784,P11142,O60664,P54646,P04350,P68371,Q9NS69,Q99497	14
Recognition of dna damage by pcna containing replication complex	0.4304106126918514	2.0396591030762568	0.0413842909337409	1.0	0.1833111861231731	25	Q15054,P27694,P35244,P40937,O94782,P12004,Q13619,Q9NZJ0,P35250	9
Signaling by met	0.463567186711306	2.0253136804249174	0.0428351646531373	1.0	0.1891316215675263	20	P22681,P40763,P12931,P42566,P46109,Q99961	6
Resolution of abasic sites ap sites	0.4080029919699336	2.0171029152854865	0.043684774479618	1.0	0.1922686571045609	30	P39748,P27694,P40937,P35244,P29372,Q86W56,P27695,P35250	8
Regulation of tnfr1 signaling	0.71254654137833	2.0133864328111284	0.0440739917757322	1.0	0.1933658940763871	6	Q96BN8,Q6GQQ9,Q12933	3
Inlb mediated entry of listeria monocytogenes into host cell	0.7496448625253836	1.9965413532510343	0.0458750291985396	1.0	0.1983443543310261	5	P42566,Q99961	2
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex	0.5922807995239499	1.987946415290076	0.0468176165905624	1.0	0.2009377208948986	9	Q04917,P14635,P62258,P27348,P31946	5
Cell cycle checkpoints	0.3358456302475675	1.982440482947268	0.0474299624451315	1.0	0.2029356287900055	140	P62805,Q13200,P62333,P43686,Q9UNM6,P28070,P62258,O00232,Q9UQ84,P27348,O75832,P62195,P48556,Q2NKX8,P38398,Q92547,Q9Y6G9,Q15691,P61088,P35244,P25787,O43237,P61289,O00233,Q9P258,P35998,P30153,P31946,O43929,O14980,O43242,P30154,P25789,Q92530,P42771,P49721,P35250,Q04917,P55036,P40937,Q92674,Q9NXR7,P25788,Q96EA4,P27694,P17980,Q06323,P14635,P28066,O75122,P25786,Q9UL46,O60566,P49720,P33991,P49736	56
Autophagy	0.3842021008766358	1.9729822403222557	0.0484975857642959	1.0	0.206407864001484	48	Q9NT62,P60520,Q99816,P04350,Q9NS69,Q99497,Q9Y6G9,P61088,O43237,P12931,P19784,P50542,O95352,P54646,Q8WUX9,Q9Y4P1,Q9BUF5,P11142,O60664,P68371	20
Signaling by csf3 g csf	0.6007226300844647	1.9726083620851824	0.0485401995661955	1.0	0.206407864001484	8	Q06124,P40763,Q15369,Q93034,P42224	5
Aurka activation by tpx2	0.4056309438154398	1.952452334186506	0.0508845248308196	1.0	0.2150532517314761	29	O94927,P62258,P61163,Q7Z460,P17612,Q14203,P04350,Q15691,P07437,P07900,Q14204,P43034,P30153,P61981,Q14008,Q96CS2,Q9H6D7,O75935,O14965,Q13561,P68371	21
Listeria monocytogenes entry into host cells	0.5949801712505093	1.9397428000653691	0.0524109552750915	1.0	0.2194907278490197	8	P42566,Q99961,P22681	3
Pten regulation	0.3904186541168933	1.9382861630488144	0.0525883196010674	1.0	0.2195152335019657	66	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,P62191,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P19784,Q9HCE1,P61289,Q9UNE7,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,P49721,P60900,O43242,Q15008,P25788,P28066,P17980,Q06323,Q9HC52,P25786,Q9UL46,P49720,O00231	40
Ctla4 inhibitory signaling	0.5940649272549126	1.9344960921363248	0.0530521620764519	1.0	0.2195152335019657	8	P30154,P12931,Q06124	3
Nucleotide salvage	0.5913789995876625	1.919085423302961	0.0549735239181421	1.0	0.2254403859195027	8	Q9BZX2,P07741,P00492	3
Negative regulation of mapk pathway	0.5071787370077727	1.9169057913498744	0.0552499012054963	1.0	0.2258587119053189	14	P30154,Q02750,P30086,P10398,Q99956,P30153,P31946	7
L1cam interactions	0.3706910467344346	1.915707083843182	0.0554023902575275	1.0	0.2258587119053189	39	Q9BUF5,Q96S59,O14786,Q13885,P15311,Q02750,P11142,P12931,P19784,Q96P70,Q12955,O95239,P26038,Q16512,P04350,P68371,Q16555	17
Selenoamino acid metabolism	0.385660169795956	1.9095744783240975	0.0561880237716057	1.0	0.2283877907422326	91	P61247,P62847,P62424,P32929,P46782,P62244,P62750,P05388,P62851,P42766,P62899,P15880,P14868,P54136,O43252,O43324,P49591,P62081,P62888,P46781,P08865,P46778,P62910,P08708,P47914,P18124,P62701,Q16881,P61353,P62753,P57772,P61927,P62277,Q9Y3U8,P62861,P62841,P62269,Q13155,P84098,Q9P2J5,P23526,O95340,P41252,P62854,P62906,P23396	46
Ikk complex recruitment mediated by rip1	0.7292030114788134	1.9021699624934776	0.0571489383732704	1.0	0.2309351837188879	5	P61088,Q6SZW1	2
Cytoprotection by hmox1	0.3875127419403418	1.8997949069643765	0.0574600395697855	1.0	0.2309942836663751	68	P51665,Q13200,P62333,P43686,Q9UNM6,P40763,Q86X55,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P19784,P61289,Q13616,P20618,O00233,Q13309,P35998,P63208,P28072,O00487,P25789,P28074,Q92530,P55036,P49721,O43242,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	40
Synthesis of udp n acetyl glucosamine	0.7286285492788181	1.899506951285574	0.0574978535320065	1.0	0.2309942836663751	5	O95394,Q16222	2
Fanconi anemia pathway	0.6488649426406813	1.897153160658866	0.0578077267030003	1.0	0.2315660240682508	7	Q9NVI1,P27694,P35244	3
Signaling by fgfr4	0.5760145407734825	1.892593801841552	0.0584119086676744	1.0	0.2319691315480634	9	P12931,P30153,Q06124,P22681	4
Signaling by fgfr3	0.5760145407734825	1.892593801841552	0.0584119086676744	1.0	0.2319691315480634	9	P12931,P30153,Q06124,P22681	4
Signaling by fgfr1	0.5760145407734825	1.892593801841552	0.0584119086676744	1.0	0.2319691315480634	9	P12931,P30153,Q06124,P22681	4
Synthesis of substrates in n glycan biosythesis	0.4810977733575219	1.8863591877767631	0.0592465683333125	1.0	0.2336369965474838	17	Q16222,O95394,O60547,Q06210,Q9NR45	5
Maturation of sars cov 2 nucleoprotein	0.8035826037547502	1.8859984335979572	0.0592951657409908	1.0	0.2336369965474838	4	P78362,Q96SB4	2
G2 m dna damage checkpoint	0.3803287759392879	1.8838443356867869	0.0595860344925878	1.0	0.2336369965474838	33	P38398,Q92547,Q04917,P61088,P62805,P27694,P35244,P40937,P35250,Q9UQ84,Q9NXR7,P27348,P31946	13
Retrograde transport at the trans golgi network	0.5629535919781831	1.8808344579284315	0.0599944412164363	1.0	0.2336369965474838	10	P40616,Q7Z6M1,Q96JB2,Q9UID3	4
Vxpx cargo targeting to cilium	0.5778484517290408	1.8411572347316745	0.0655985202844813	1.0	0.2497442287414688	8	Q96KP1,P18085,O60645,O00471	4
Activation of bad and translocation to mitochondria	0.6761365045982963	1.8363213467400576	0.0663101444593947	1.0	0.2514128936058025	6	Q04917,P27348,P31946	3
Polb dependent long patch base excision repair	0.6363366276113872	1.8319558579654345	0.066957997418803	1.0	0.2518325475115252	7	P39748,P27695	2
Carboxyterminal post translational modifications of tubulin	0.675085151545961	1.831169352133452	0.0670752696573964	1.0	0.2518325475115252	6	P68371,Q9BUF5,Q13885,P04350	4
Map3k8 tpl2 dependent mapk1 3 activation	0.788916562889165	1.823302006565814	0.0682576625800854	1.0	0.252717952306523	4	O15111,Q13616,P63208	3
Recycling of eif2 gdp	0.5747083511724187	1.823003702447582	0.0683028301336521	1.0	0.252717952306523	8	P05198,P41091,Q13144,Q9NR50,Q14232	5
Copi mediated anterograde transport	0.3752979172702516	1.8212163634355216	0.0685739740339697	1.0	0.252717952306523	55	Q8N6T3,P61163,Q92538,Q14203,P04350,Q9NZ32,P47755,Q9Y678,Q9Y6G9,Q13885,P52907,O43237,O15498,Q12955,Q14204,P18085,P53618,Q96JB2,P48444,P47756,O75935,Q9BUF5,Q15363,Q9UBF2,P84085,Q13561,P68371,P35606	28
Oncogenic mapk signaling	0.3785530069138018	1.8170529913606572	0.069208999719508	1.0	0.254379887266915	32	O95352,P12931,P30086,P21359,Q9NRY5,Q99956,P31946	7
Metabolism of porphyrins	0.5623895480255579	1.8121652187118855	0.0699606715366294	1.0	0.2549755405214972	9	P08397,P06132	2
Mastl facilitates mitotic progression	0.7084563701998937	1.80563402284346	0.0709755245907215	1.0	0.2554379556884822	5	Q96GX5,P30154,P30153	3
Gamma carboxylation hypusine formation and arylsulfatase activation	0.5308004585306926	1.802923440657275	0.0714002390941468	1.0	0.256188251889716	11	Q8NBJ7,Q9BZG8,Q9H2P9,Q9BU89	4
Sealing of the nuclear envelope ne by escrt iii	0.5487545102341814	1.7949487224501957	0.0726618701512156	1.0	0.2594798567157105	10	P53990,Q9BUF5,Q13885,Q8NC56,Q8WUX9,P04350,P68371	7
Aggrephagy	0.4780013466543398	1.78756390620456	0.0738463930870327	1.0	0.2615118719497126	16	Q9Y6G9,Q9BUF5,P61088,O43237,P04350,P68371,Q99497	7
Tgf beta receptor signaling activates smads	0.5281579596156039	1.786259710876358	0.0740572170359472	1.0	0.2615118719497126	11	O14980,Q9Y3F4,P22681,P61081,P62942,Q13485,Q9Y5K5	7
Dna damage reversal	0.7041529315964941	1.7855198853503442	0.0741770288019445	1.0	0.2615118719497126	5	Q9C0B1	1
Translesion synthesis by y family dna polymerases bypasses lesions on dna template	0.4183946501678242	1.770718633809864	0.0766075022419014	1.0	0.2668673882414695	22	Q15054,P28340,P27694,P35244,P40937,P35249,P12004,Q07864,P55072,Q14694,Q8TAT6,Q14258,P35250	13
Signalling to erks	0.5444715764415344	1.7689410383627029	0.0769037147002063	1.0	0.2670375218987063	10	P12931,Q16539,P46109,P31946	4
Response of eif2ak4 gcn2 to amino acid deficiency	0.3760344248720306	1.7567063090966646	0.0789678816038454	1.0	0.2728340309412861	77	P08243,P05198,P41091,P61247,P62847,P46782,P62244,P62750,P05388,Q92616,P62851,P42766,P62899,P15880,P62081,P46781,P08865,P46778,P62910,P08708,P47914,P18124,P62701,P61353,P62753,P62277,P62861,Q9Y3U8,P62841,P62269,P84098,P62854,P62906,P23396	34
Ovarian tumor domain proteases	0.5491082756399785	1.733315381927809	0.0830396282595962	1.0	0.2830942670466503	9	Q6GQQ9,Q96FW1	2
Crmps in sema3a signaling	0.6163913991897826	1.7274817656535078	0.0840811771868772	1.0	0.2830942670466503	7	Q14195,O14531,Q9BPU6,O14786,Q16555,Q00535	6
Nuclear events kinase and transcription factor activation	0.5375446608732429	1.7267851390990596	0.0842062583940288	1.0	0.2830942670466503	10	P30154,P51452,Q00535,Q16539,P30153	5
Mtorc1 mediated signalling	0.5184822838511522	1.7250943632066222	0.0845104682202873	1.0	0.2830942670466503	11	P62942,Q96B36	2
Tnfr1 induced nfkappab signaling pathway	0.653346001895455	1.7241882079181965	0.0846738722141475	1.0	0.2830942670466503	6	Q6GQQ9,Q12933	2
Extension of telomeres	0.3647376252276631	1.7237263922093795	0.0847572481885783	1.0	0.2830942670466503	33	Q9Y265,Q15054,P39748,Q8WVB6,P27694,P35244,P40937,P09884,P12004,P49643,O00743,P49642,Q9BUR4,P35250	14
Regulation of signaling by cbl	0.6908996764081505	1.7233931300235297	0.084817456418732	1.0	0.2830942670466503	5	P46109	1
Rhou gtpase cycle	0.474312587487528	1.7233223012445429	0.0848302570327601	1.0	0.2830942670466503	15	P12931,Q13177,O43396,P16333,Q16512	5
Signaling by scf kit	0.5043820427778283	1.7158377572194852	0.0861917414314024	1.0	0.2857517590372085	12	Q06124,P40763,P22681,P12931,O14757	5
G1 s specific transcription	0.5558503097446209	1.7134779252447114	0.08662465107876	1.0	0.2857517590372085	8	P12004,P09884,P31350	3
Hdr through single strand annealing ssa	0.4718308920461453	1.7057850647141062	0.0880481048607686	1.0	0.2857517590372085	15	P38398,P27694,P35244,P40937,Q9UQ84,P35250	6
Eph ephrin signaling	0.3629155370714854	1.7049712017835463	0.0881997955295084	1.0	0.2857517590372085	33	P60660,O15143,P59998,Q16512,P23528,P12931,O15144,P35580,O00401,Q13177,P35579,P61160,Q7Z406,Q13464,Q92747,P09496,O15145,O75116,Q05397	19
Polymerase switching on the c strand of the telomere	0.4564679772387529	1.704673037407815	0.088255421175599	1.0	0.2857517590372085	17	Q15054,Q8WVB6,P40937,P09884,P12004,P49643,P49642,P35250	8
E3 ubiquitin ligases ubiquitinate target proteins	0.4451363962567059	1.697907994052221	0.08952512824611	1.0	0.2884002965877018	18	P61088,Q14527,P68036,P50542,P12004	5
Glutathione synthesis and recycling	0.6473241867986728	1.6944100325296736	0.0901873944268012	1.0	0.2891855663522953	6	Q8WUX2,Q96KP4,P48637	3
Tak1 activates nfkb by phosphorylation and activation of ikks complex	0.6825199161774385	1.6839779189382804	0.0921859362006201	1.0	0.2928757789178321	5	P09429,P61088	2
Parasite infection	0.3860375452514536	1.666830814486009	0.0955480511018249	1.0	0.3014780973121509	26	Q9UQB8,O00401,Q92747,P12931,Q9Y6W5,P35579,P59998,P16333,P61160,O15144,O15145,Q05397	12
Transport to the golgi and subsequent modification	0.3677481519546872	1.659785239293032	0.0969576642343912	1.0	0.3052289110977874	77	O95487,Q8N6T3,O15155,P61163,Q92538,P55735,P33908,P04350,Q9NZ32,Q14203,P47755,Q9Y678,Q9Y6G9,Q5H9R7,Q13885,P52907,Q9H0V9,O43237,O15498,Q86SZ2,Q12955,Q14204,O14579,P18085,Q8IUR0,P53618,Q96JB2,O95486,Q15436,P48444,P47756,O15027,O75935,Q9BUF5,Q15363,P84085,Q9UBF2,O00743,Q13561,P68371,P35606	41
Gap junction assembly	0.7499999999999991	1.655601589908814	0.0978025280055157	1.0	0.3064922759719335	4	P68371,Q9BUF5,P04350	3
Transport of connexons to the plasma membrane	0.7499999999999991	1.655601589908814	0.0978025280055157	1.0	0.3064922759719335	4	P68371,Q9BUF5,P04350	3
Fcgamma receptor fcgr dependent phagocytosis	0.3531382210581449	1.652233340134752	0.098486992320721	1.0	0.3076872474029211	34	Q9UQB8,O00401,Q05397,Q92747,P12931,Q9Y6W5,P35579,O15143,O15145,P59998,P16333,P61160,Q16512,O15144,P08238,O43865	16
Tbc rabgaps	0.4480134911245151	1.641939874623832	0.1006024651358852	1.0	0.3111932448974452	17	P60520,Q9UJY4,Q9BXI6,Q4KMP7,P62330,Q9NVG8	6
Synthesis of active ubiquitin roles of e1 and e2 enzymes	0.5336952826080352	1.6413140274791678	0.1007322457336592	1.0	0.3111932448974452	9	P68036,Q96BN8,P61086,P45974,A0AVT1	5
Transcriptional regulation by runx1	0.3647332108177726	1.6364191674716493	0.1017518903433771	1.0	0.313187332860907	69	P51665,P62805,Q13200,P62333,Q9UNM6,P43686,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,Q06124,P25787,P12931,P19784,P61289,P20618,O00233,P35998,Q00534,P28072,O00487,P25789,P28074,Q92530,P55036,P49721,O43242,Q15008,P25788,Q99873,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	40
M phase	0.2327141793436492	1.6224641485909117	0.1047040035006625	1.0	0.3208446404388373	191	P51665,P53990,P62805,Q13200,P62333,P43686,O94927,P28070,P62258,Q8NC56,Q9UNM6,O00232,Q8TD19,O75832,P04350,Q96GX5,Q9HC35,P48556,P62195,P63151,Q2NKX8,Q9Y6G9,Q15691,Q86XI2,Q13885,P25787,O43237,P07437,P19784,P06400,P61289,Q99986,P20618,O00233,Q9P258,P35998,P30153,O14980,O43242,P30154,P25789,Q92530,O00487,P28074,P49721,P55036,Q15003,Q15021,Q92674,Q96CS2,Q15008,P25788,Q9H8Y8,Q96CW5,Q8WUX9,Q96EA4,Q9UN37,Q14739,O75935,Q9BUF5,P17980,Q06323,P14635,P28066,O75122,P25786,Q9UL46,Q13561,O60566,Q7Z5K2,P68371,P49720	72
Cytosolic sulfonation of small molecules	0.6670366570242768	1.6109031980096131	0.1072008228811141	1.0	0.3271478513365613	5	O95340,Q96IU4,O43252	3
Base excision repair	0.3536784156149963	1.6098251051757764	0.1074360428792835	1.0	0.3271478513365613	33	Q15054,P39748,P62805,P27694,P35244,P40937,P29372,P12004,Q86W56,P27695,P35250	11
Attenuation phase	0.5003009591689553	1.6095940183822603	0.1074865149225201	1.0	0.3271478513365613	11	P54652,P0DMV9,P11142,Q92598,Q02790,Q15185,P25685,P08238	8
Intra golgi and retrograde golgi to er traffic	0.3628540229690745	1.6027105130337105	0.108998581389403	1.0	0.3302832881820249	79	Q8N6T3,Q9NQT8,P61163,Q92538,Q15102,P33908,P04350,Q9NZ32,P40616,Q9H0H5,Q14203,P47755,Q07866,Q9Y678,Q9Y6G9,Q13885,P52907,Q9UID3,O43237,O15498,O95239,Q14204,P68402,P18085,O43264,P53618,Q96JB2,P48444,P47756,O75935,Q9BUF5,P84085,Q9UBF2,Q7Z6M1,O60664,Q9Y496,Q10471,O15260,Q13561,P68371,P35606	41
Rhob gtpase cycle	0.3818412577059489	1.601717312225655	0.1092181350934771	1.0	0.3302832881820249	25	Q9NQW6,Q16513,Q13464,O00161,Q92974,Q16512,Q9H0H5,Q9UDY2,O60610,Q92888	10
Rab gefs exchange gtp for gdp on rabs	0.3784788103316863	1.5972443612978595	0.1102112477472037	1.0	0.3325588305385055	26	Q8IUR0,P62258,Q86SZ2,P20336,P61020,P51148,P20339,P50395,Q14C86,Q7Z392	10
Caspase activation via extrinsic apoptotic signalling pathway	0.6638181959720082	1.59567644857834	0.1105610494496587	1.0	0.3328875170793646	5	Q9UKG1	1
Termination of translesion dna synthesis	0.4209149290747967	1.5924806134655658	0.1112767557125655	1.0	0.3335888858888625	19	Q15054,P27694,P35244,P40937,P12004,Q14258,P35250	7
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10	0.7339086669120858	1.5857760022437466	0.112790131303607	1.0	0.3363184686909858	4	Q14258	1
Methionine salvage pathway	0.9078864349558012	1.5848239782670823	0.1130063328148045	1.0	0.3363184686909858	3	Q13126	1
Erk mapk targets	0.589250968908555	1.584145112387223	0.1131607003916848	1.0	0.3363184686909858	7	P30154,Q16539,P30153	3
Mapk targets nuclear events mediated by map kinases	0.589250968908555	1.584145112387223	0.1131607003916848	1.0	0.3363184686909858	7	P30154,Q16539,P30153	3
Er to golgi anterograde transport	0.3608547221039322	1.5798905038323832	0.1141319443182828	1.0	0.3384771395876973	76	Q8N6T3,O95487,O15155,P61163,Q92538,P55735,Q14203,P04350,Q9NZ32,P47755,Q9Y678,Q9Y6G9,Q5H9R7,Q13885,P52907,Q9H0V9,O43237,O15498,Q86SZ2,Q12955,Q14204,O14579,P18085,Q8IUR0,P53618,O95486,Q96JB2,Q15436,P48444,P47756,O15027,O75935,Q9BUF5,Q15363,Q9UBF2,P84085,O00743,Q13561,P68371,P35606	40
Synthesis of diphthamide eef2	0.7303860523038594	1.570458953653351	0.116308376441464	1.0	0.3441930968781657	4	P13639,Q9BZG8,Q9H2P9	3
Assembly of the orc complex at the origin of replication	0.5861667184318415	1.567783289342155	0.1169317160608325	1.0	0.3444984327736917	7	O43929,P52294,P62805,Q14974,O60684	5
Ephrin signaling	0.7280382482556114	1.5602445562844418	0.1187020999947323	1.0	0.3475557249845765	4	P12931,Q16512	2
Interconversion of nucleotide di and triphosphates	0.4257336466399228	1.5494079906963472	0.1212836740988694	1.0	0.3528716581150264	18	P31350,Q9Y3D8,Q16881,P17812,P15531,P32321,P00568,P23921,Q9NRF8,Q9H773,P23919,P33316	12
Homologous dna pairing and strand exchange	0.44389834899113	1.5415187719043275	0.1231905778121129	1.0	0.3561702479839751	16	P38398,P27694,P35244,P40937,Q9UQ84,P35250	6
Interleukin 6 family signaling	0.7226027397260263	1.5365803160523603	0.124396115872623	1.0	0.3564440578109521	4	P40763,Q06124,P22681	3
Interleukin 6 signaling	0.7226027397260263	1.5365803160523603	0.124396115872623	1.0	0.3564440578109521	4	P40763,Q06124,P22681	3
Sema3a pak dependent axon repulsion	0.5783821146985177	1.5264305279176285	0.1269026797093337	1.0	0.3608631756343606	7	O14786,Q13177,Q16512,P08238,P23528	5
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways	0.4866592254408819	1.5225462752157342	0.1278722596492167	1.0	0.362873640318722	11	Q9Y2Z0,Q16539,P61088,P42575	4
Lipophagy	0.7179248041327327	1.5161971534929737	0.1294695076261609	1.0	0.3653725199667887	4	P54646,P11142	2
Regulation of kit signaling	0.6469925746954232	1.515894730120839	0.1295459730707138	1.0	0.3653725199667887	5	P22681	1
Death receptor signalling	0.3874676501753906	1.5071299338252957	0.1317773553999617	1.0	0.3688076966165023	22	P62258,Q92974,Q12933,P42575,Q96BN8,Q6GQQ9,Q92888	7
Inactivation of csf3 g csf signaling	0.6084861095832872	1.501105495909157	0.1333282775497428	1.0	0.3717590973137054	6	P42224,Q15369,Q93034,P40763	4
Regulation of bach1 activity	0.7122489130617911	1.4914463812887924	0.1358443386188423	1.0	0.3739778405801597	4	P63208,Q13616	2
Advanced glycosylation endproduct receptor signaling	0.6046711159846874	1.4820224273777385	0.1383343275572661	1.0	0.3778222147907941	6	P09429,P47755	2
Rho gtpases activate iqgaps	0.4967221644869091	1.4764646017189065	0.1398192112564487	1.0	0.378882646973357	10	P68371,Q9BUF5,Q13885,P04350	4
Activation of bh3 only proteins	0.5052801779116703	1.4706125492092097	0.1413959282105759	1.0	0.3820585246546348	9	Q04917,P27348,P31946	3
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects	0.7068002434753531	1.4676688562296338	0.1421941943508635	1.0	0.3822007588069325	4	Q00534,P11802	2
Metabolism of nitric oxide nos3 activation and regulation	0.5657042731960369	1.458936722573513	0.1445825246245022	1.0	0.3864855880678184	7	O00401,O95865,P50570,P35270,Q9Y314	5
Negative regulation of met activity	0.5653043267591729	1.4568049780452554	0.145170221386031	1.0	0.3873074246245076	7	P42566,Q99961	2
Gab1 signalosome	0.7003001577064021	1.4392838648292872	0.1500701124685983	1.0	0.3980746553389691	4	P12931,Q06124	2
Cell extracellular matrix interactions	0.5074501319293527	1.4292433035048848	0.1529343153779545	1.0	0.4041208869069468	8	Q15404,Q96AC1	2
Signaling by ntrk2 trkb	0.5554577921163811	1.404283995950566	0.1602342980295368	1.0	0.4201969637131306	7	P12931,Q00535	2
Nod1 2 signaling pathway	0.5021434612955161	1.397902966580775	0.1621422077149081	1.0	0.4243949451931876	8	Q16539,P61088,P42575	3
Dna damage recognition in gg ner	0.3956297036418131	1.3925115605058982	0.1637675433805472	1.0	0.4257814342655568	19	Q9Y265,Q9BT78,Q9UNS2,P61201,Q92905,Q7L5N1,Q13619,Q99627,Q16531	9
Traf6 mediated irf7 activation	0.6893003407833571	1.3912132938312185	0.1641607571991881	1.0	0.4257814342655568	4	Q12933	1
Nonsense mediated decay nmd	0.34401140278079	1.389119517363046	0.16479640976702	1.0	0.4257814342655568	86	P62495,P61247,P62847,P46782,Q04637,P62244,P62750,Q8ND04,P05388,P63151,P42766,P62899,P15880,P30153,P62081,P46781,P08865,P46778,P62910,P08708,P47914,P18124,P62701,P62277,P62861,Q9Y3U8,P62841,P62269,P84098,P15170,P62854,P62906,P23396	33
Tnfr1 induced proapoptotic signaling	0.8570646268978752	1.3887471197793413	0.1649096603404722	1.0	0.4257814342655568	3	Q6GQQ9	1
Meiotic recombination	0.4543877512521532	1.387617924315317	0.1652534204364748	1.0	0.4257814342655568	12	P38398,P27694,P35244,P11802,Q9BWT6	5
Signaling by braf and raf1 fusions	0.3556565456274265	1.3871067616823292	0.1654092104955575	1.0	0.4257814342655568	26	Q02750,P12931,O95352,P30086,P10398,O43252,P41240,Q9NRY5,P31946	9
Cell cycle	0.2449659293919744	1.3852095723143096	0.1659883945691984	1.0	0.4257814342655568	305	P43686,P28070,P12004,Q9UQ84,P27348,P31350,P48556,P63151,P38398,Q92547,P35244,Q9BWT6,Q9BRT9,Q9Y570,Q13309,O43929,O14980,O43242,Q9BRX5,P11802,Q96CS2,Q9NXR7,Q9H8Y8,Q96CW5,Q8WUX9,P25788,Q14739,Q9BUF5,Q06323,Q9UL46,O60566,P49736,Q8NF91,P53990,P62805,Q13200,P62333,P62258,Q8TD19,Q9Y6G9,Q15691,P25787,O43237,P04183,P06400,P61289,P49642,P35998,P30153,P31946,Q00534,P30154,P25789,P39748,P42771,Q8WVB6,P49721,Q92530,Q15003,Q15021,Q92674,Q96EA4,P17980,P14635,O75122,P25786,Q13561,P68371,Q9BUR4,P51665,Q9UH99,O94927,Q8NC56,O00232,P04350,Q96GX5,Q9HC35,Q9Y265,Q15054,P61088,Q13885,P07437,P12931,P19784,P09884,P49643,Q99986,P20618,P21127,Q9P258,O00487,P28340,O00743,P49720,P33991,Q9UNM6,O75832,P62195,Q2NKX8,Q86XI2,Q13616,O00233,P35250,P63208,Q04917,P55036,P40937,O75935,P27694,P28066,Q7Z5K2	111
Late endosomal microautophagy	0.4998059759821939	1.3840931775163527	0.166329925695932	1.0	0.4257814342655568	8	P11142,Q99497,Q8WUX9,Q99816	4
Synthesis of pips at the early endosome membrane	0.6872088082303134	1.3820694395834896	0.1669503808898049	1.0	0.4257814342655568	4	O00443,Q13614	2
Interleukin 3 interleukin 5 and gm csf signaling	0.4986747618715378	1.377409158023023	0.1683857830569537	1.0	0.4277473854612396	8	P46109,P22681	2
Intracellular signaling by second messengers	0.3404857839488601	1.372238671574608	0.1699891504130426	1.0	0.4286952661876367	94	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,Q06124,O15111,P25787,P12931,P19784,P61289,P20618,O00233,Q96B36,P35998,P30153,O43865,O43242,P30154,P25789,Q92530,O00487,P28074,P49721,P28072,P55036,Q15008,P25788,Q8TBX8,P17980,Q06323,P28066,P25786,Q9UL46,O60346,P49720,O00231	44
Regulation of runx1 expression and activity	0.6132046091559994	1.3550420270155272	0.1754041674018447	1.0	0.4388163090297955	5	Q00534,Q9HCE1,P12931,Q06124	4
Ticam1 rip1 mediated ikk complex recruitment	0.680894155303881	1.3544588659512924	0.1755900281428921	1.0	0.4388163090297955	4	P61088	1
Oncogene induced senescence	0.5433744161708891	1.33976131308752	0.1803229568677051	1.0	0.4468448712578078	7	Q00534,P42771,P11802	3
Synthesis of pyrophosphates in the cytosol	0.8442379192663639	1.3392589449872183	0.1804863890441532	1.0	0.4468448712578078	3	Q92551	1
Regulation of tp53 activity through phosphorylation	0.3230775667224213	1.337480206049085	0.1810659391493287	1.0	0.4468448712578078	34	P38398,Q92547,P27694,P35244,P40937,Q16539,P19784,Q96S44,Q9UQ84,Q00535,P35250	11
Prolactin receptor signaling	0.676013899008624	1.3331184233156728	0.1824929443682761	1.0	0.4495637239161454	4	P63208,Q13616	2
Negative regulation of the pi3k akt network	0.4212214397891712	1.3191504621173615	0.1871188157290024	1.0	0.4555645598618354	14	P30154,Q06124,P12931,O60346,P30153	5
Golgi to er retrograde transport	0.3363475157883084	1.317998618790827	0.1875041102800989	1.0	0.4555645598618354	68	Q8N6T3,Q9NQT8,P61163,Q92538,Q15102,Q14203,Q9H0H5,P04350,Q9NZ32,P47755,Q07866,Q9Y678,Q9Y6G9,Q13885,P52907,O43237,O95239,Q14204,P68402,P18085,O43264,P53618,P48444,P47756,O75935,Q9BUF5,Q9UBF2,P84085,Q9Y496,Q10471,O15260,Q13561,P68371,P35606	34
Processive synthesis on the c strand of the telomere	0.432477722990526	1.317156337712941	0.187786225972562	1.0	0.4555645598618354	13	P28340,P39748,Q15054,P27694,P35244,P12004	6
Vitamin b5 pantothenate metabolism	0.6050373926510723	1.31610105811468	0.188140125888617	1.0	0.4555645598618354	5	Q9NVE7	1
Activated tak1 mediates p38 mapk activation	0.6713791438875034	1.3128524340535574	0.1892326775676198	1.0	0.4555645598618354	4	P61088	1
Separation of sister chromatids	0.3287300528788448	1.3028444055609594	0.1926278871369153	1.0	0.458985758660719	106	P51665,Q13200,P62333,P43686,Q9UNM6,P28070,O00232,O75832,P04350,P62195,Q99460,P48556,Q99436,Q2NKX8,Q9Y6G9,Q15691,Q13885,P25787,O43237,P61289,P20618,O00233,Q9P258,P35998,P30153,O14980,O43242,P30154,P25789,Q92530,O00487,P28074,P49721,P28072,P55036,Q92674,Q15008,P25788,Q96EA4,Q9BUF5,P17980,Q06323,P28066,O75122,P25786,Q9UL46,Q7Z5K2,O60566,P68371,P49720,O00231	51
Met receptor recycling	0.5997942123874604	1.2911029336589546	0.1966679869479315	1.0	0.4595364223923889	5	P46109	1
Erks are inactivated	0.5992830454344976	1.2886660572545705	0.1975142075984652	1.0	0.4595364223923889	5	P30154,P30153	2
Tp53 regulates transcription of cell cycle genes	0.4150061800532176	1.2757244475736405	0.2020529432665756	1.0	0.4671556792799807	14	Q92600,O75175,P14635,Q9UIV1,P12004,Q99873	6
Activation of rac1	0.5632361162026202	1.2742253740658194	0.2025835550924135	1.0	0.4671556792799807	6	P16333,Q16512	2
Synthesis of pips at the late endosome membrane	0.8227736488842075	1.25658007421982	0.2089057337324447	1.0	0.4702080195736784	3	Q13614	1
Cellular response to starvation	0.3318287291720044	1.2553991357545224	0.2093339029338898	1.0	0.470405616023798	90	P08243,P05198,P36543,P41091,P61247,P62847,P46782,P62244,P62750,P05388,Q92616,P55735,P62851,P42766,Q8NFG4,P62899,P15880,P62081,P46781,P08865,P46778,P62910,P08708,P47914,P18124,P62701,P61353,P62753,P62277,P62861,Q9Y3U8,P62841,P62269,Q9UI12,P84098,P21283,P62854,P62906,P23396	39
Cellular response to chemical stress	0.3324508891351101	1.2518967546804605	0.2106074874752912	1.0	0.4717609685464264	78	P51665,Q13200,P62333,P43686,P40763,P28070,Q86X55,Q9UNM6,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P19784,P61289,Q13616,P20618,O00233,Q13309,P35998,P63208,O43242,O00487,P25789,Q92530,P28074,P30041,P49721,P28072,P55036,Q15008,P25788,P17980,Q06323,P28066,P25786,Q9UL46,P32119,P49720,O00231	42
Cd28 dependent vav1 pathway	0.5894672510102505	1.2418871682209114	0.2142781951161674	1.0	0.4776330091137796	5	Q16512	1
Hdr through homologous recombination hrr	0.3393621570045808	1.237928082220939	0.2157427285686921	1.0	0.4779223171535908	26	P38398,P27694,P35244,P40937,P12004,Q9UQ84,P35250	7
Processing of dna double strand break ends	0.3351154598926891	1.2221937469492925	0.2216343679807759	1.0	0.4841038684306177	27	P38398,Q92547,P61088,P62805,P27694,P35244,P40937,Q9UQ84,Q9NXR7,P60510,P35250	11
Condensation of prometaphase chromosomes	0.4552969882750555	1.2210767759247758	0.2220569519518869	1.0	0.4841038684306177	10	P14635,Q15003,P19784,Q15021	4
Prolonged erk activation events	0.5848125482335323	1.219719992669844	0.2225710399740128	1.0	0.4841038684306177	5	P46109,P31946	2
Dscam interactions	0.8130339176814658	1.219153699950972	0.2227858613038154	1.0	0.4841038684306177	3	Q16512	1
Gap filling dna repair synthesis and ligation in gg ner	0.3622174017016329	1.202682217728092	0.2290993177712255	1.0	0.4965981042845905	20	Q15054,P27694,P40937,P35244,P12004,P35250	6
E2f enabled inhibition of pre replication complex formation	0.579491579243689	1.194397809874912	0.2323223931470115	1.0	0.5016711677018281	5	O43929	1
Map2k and mapk activation	0.3996349904761175	1.1929458935813393	0.2328905638940539	1.0	0.5021135090508307	15	Q02750,P12931,P30086,P10398,P41240,P31946	6
Association of tric cct with target proteins during biosynthesis	0.3949788161541233	1.1875118629442318	0.2350257801185862	1.0	0.504356565409761	16	P50991,Q15477,P40763,Q9Y2T2,P40227,Q99832,P50990,P17987,P48643,P78371,Q9BUR4	11
Diseases associated with glycosylation precursor biosynthesis	0.4661635953112019	1.1854044230536969	0.2358575837791159	1.0	0.5053568694306019	8	Q06210,P34949,P36871	3
Regulation of tp53 expression and degradation	0.4567972311352314	1.1782768290666712	0.2386862621129595	1.0	0.5106260282354644	9	P30154	1
Iron uptake and transport	0.3834397356742118	1.1618443145432935	0.2452987098500001	1.0	0.5196428703906993	17	P63208,P36543,P21283,Q13616,O76003,P21399,Q9UI12	7
Processing and activation of sumo	0.8074051026758018	1.1521564981075578	0.2492567700628645	1.0	0.5243118055203634	2	Q9UBE0	1
Sumo is transferred from e1 to e2 ube2i ubc9	0.8074051026758018	1.1521564981075578	0.2492567700628645	1.0	0.5243118055203634	2	Q9UBE0	1
Sumo is conjugated to e1 uba2 sae1	0.8074051026758018	1.1521564981075578	0.2492567700628645	1.0	0.5243118055203634	2	Q9UBE0	1
Regulation of localization of foxo transcription factors	0.6338111161788922	1.148895103901853	0.2505992367806178	1.0	0.5258592746498795	4	P31946	1
Rhoq gtpase cycle	0.3452684869365636	1.1485212500075686	0.2507534457266791	1.0	0.5258592746498795	22	Q9Y6M7,O00401,Q07960,O00161,Q13177,Q15642,Q16512,Q9HD26	8
Cd28 co stimulation	0.4505837112725977	1.1409619658637806	0.2538857508910848	1.0	0.5300152684765546	9	P12931,Q16512	2
Serine biosynthesis	0.8042937149968903	1.1396291024033358	0.2544408555117352	1.0	0.5302934827670747	2	Q9Y617	1
Homology directed repair	0.3009663654438646	1.1246443387012732	0.2607397770719677	1.0	0.5370229089619365	42	Q9UNS1,Q92547,Q15054,P61088,P62805,P38398,P35244,P28340,P39748,P40937,P27694,P12004,Q9UQ84,Q9NXR7,P60510,P35250	16
Transcriptional regulation of granulopoiesis	0.5310274956077928	1.112935754536748	0.2657360227343599	1.0	0.5435764844808726	6	P11802,P40763	2
Apoptotic factor mediated response	0.5309564337327015	1.1125811665868934	0.265888352756201	1.0	0.5435764844808726	6	O14727	1
Wnt ligand biogenesis and trafficking	0.5620310597712531	1.111503276192937	0.2663517806382747	1.0	0.5437195876544987	5	Q96QK1,O60493,O75436	3
Dna replication initiation	0.4519925858804061	1.102081429502848	0.2704262720502846	1.0	0.5492517202354812	8	P49643,P09884	2
Rho gtpases activate paks	0.4100937086318454	1.0970183576190624	0.2726333672840844	1.0	0.5492517202354812	12	P21333,P60660,Q13177,P35579,Q7Z406,Q14247,Q16512,P35580,P62140	9
Golgi associated vesicle biogenesis	0.3144568230320045	1.080795953877035	0.2797878886854703	1.0	0.5590583935573438	29	O43747,O95295,Q14671,P78537,Q9Y5X3,Q13492,Q9Y5X1,Q9BXS5,O14976,P11142,O00443,P54920,P09496,O00203,P50570,P51148,Q14677	17
Signaling by leptin	0.7893590541381532	1.0797293297042645	0.2802627291715924	1.0	0.5590583935573438	2	P40763	1
Netrin mediated repulsion signals	0.7893590541381528	1.0797293297042614	0.2802627291715938	1.0	0.5590583935573438	2	P12931	1
Grb2 sos provides linkage to mapk signaling for integrins	0.6178359397686525	1.0795597935518668	0.2803382537881616	1.0	0.5590583935573438	4	P12931,Q05397	2
Diseases of immune system	0.7887367766023721	1.0772426211082495	0.2813718888441729	1.0	0.5603111676983388	2	P09429	1
Pyrimidine salvage	0.7871810827629221	1.0710293030264608	0.2841562540890097	1.0	0.5634202914648657	2	Q9BZX2	1
Cyclin a b1 b2 associated events during g2 m transition	0.4032432118558279	1.052567773384131	0.2925391336371552	1.0	0.577555832409355	12	O14980,P30154,Q9Y570,P63151,P30153	5
Tp53 regulates transcription of genes involved in g2 cell cycle arrest	0.4871601944036047	1.040499359277642	0.2981079615747286	1.0	0.58623732616953	7	P14635,P12004,Q99873	3
Mtor signalling	0.3775953831592329	1.0382590871678126	0.2991494505699732	1.0	0.5872507680223055	15	P62942,Q96B36	2
Rho gtpases activate pkns	0.3497593617778757	1.033497903031648	0.3013709513476232	1.0	0.5897385715590091	19	Q04917,Q16513,P62805,P62258,P35579,P27348,Q16512,P31946	8
Purine salvage	0.512251519818184	1.019579248065975	0.3079280510201574	1.0	0.5993754457885317	6	P07741,P55263,P00492,Q9P2T1	4
Met promotes cell motility	0.4357689999846714	1.007336154615519	0.3137732611135089	1.0	0.6073314381776881	8	P46109	1
Signaling by moderate kinase activity braf mutants	0.3614927218960258	1.0015741338620932	0.316549318819098	1.0	0.6095423045789223	17	Q02750,P12931,P30086,P10398,P41240,P31946	6
Activation of ppargc1a pgc 1alpha by phosphorylation	0.7507896932488128	0.982630691075757	0.3257892335570085	1.0	0.6199368145386132	3	Q16539	1
Flt3 signaling	0.5034272693770458	0.9759951403978944	0.3290668725337005	1.0	0.6199368145386132	6	Q06124,P22681	2
Galactose catabolism	0.7610454262601121	0.9674832975473854	0.3333024869349013	1.0	0.6258478762826543	2	Q96G03	1
Synthesis of gdp mannose	0.7594897324206673	0.9613761777295008	0.3363630577919454	1.0	0.6290307792536788	2	P34949	1
Synthesis of ip2 ip and ins in the cytosol	0.7445336407215594	0.95923939727895	0.3374381574291072	1.0	0.6301885588743598	3	Q9NPH2	1
Signal regulatory protein family interactions	0.5291601866238262	0.9569067828053882	0.3386143073627834	1.0	0.6315316771597391	5	P12931,Q06124	2
Synthesis of pips at the plasma membrane	0.3874775425468599	0.9512356927914664	0.3414847432785595	1.0	0.6351708145504296	12	Q9BTU6,Q96T51,Q13614,O00443,Q8TBX8	5
Phenylalanine and tyrosine metabolism	0.5274090093613856	0.9487490078962816	0.3427482820655125	1.0	0.636664147600186	5	P16930	1
Sensory processing of sound	0.338333549582443	0.9463709488750386	0.3439594174871754	1.0	0.6370809364242593	19	Q6IBS0,P52907,P15311,P35579,P23634,P20336,Q14651,P26038,P47756,P47755	10
Raf independent mapk1 3 activation	0.4968173650587507	0.9435041197480152	0.3454231090672675	1.0	0.6382015196938016	6	Q06124,Q99956	2
Uptake and function of diphtheria toxin	0.585927770859276	0.9424518798754898	0.3459613365338758	1.0	0.6383425461813304	4	P13639,P08238,Q16881	3
Hsf1 dependent transactivation	0.3595957529184755	0.9367629649416686	0.3488804996413819	1.0	0.6420144480750862	16	P54652,P0DMV9,P11142,Q92598,Q02790,Q15185,P25685,Q96B36,P08238	9
Endosomal sorting complex required for transport escrt	0.4232676382214376	0.935029241372252	0.3497732300137302	1.0	0.6428013349454456	8	Q9UN37,Q8WUX9,Q9NP79,Q99816	4
Cooperation of pdcl phlp1 and tric cct in g protein beta folding	0.3842100137836925	0.9304410791910674	0.352142757687095	1.0	0.6462965353566604	12	P50991,P40227,P19784,Q99832,P50990,P17987,P48643,P78371	8
Response of eif2ak1 hri to heme deficiency	0.5219557770165066	0.9234101650371924	0.3557934964077596	1.0	0.6504055714755606	5	P08243,Q13322,P05198,P41091	4
Generation of second messenger molecules	0.5214423988448673	0.9210299967987436	0.3570347661567887	1.0	0.6509831899740597	5	P16333,Q16512	2
Cytochrome c mediated apoptotic response	0.5808810265027581	0.9209978270464946	0.3570515615053091	1.0	0.6509831899740597	4	O14727	1
Signaling by kit in disease	0.4640464546535354	0.919330161788506	0.3579229061781468	1.0	0.6517120636866917	7	P40763	1
Semaphorin interactions	0.3026863424409768	0.9110962967405708	0.3622446375164765	1.0	0.6561233146104463	26	Q14195,O14531,O14786,P60660,Q9BPU6,Q13464,Q13177,P08238,P35579,O75116,Q9Y490,Q16512,P07900,P49841,Q7Z406,Q16555,P23528,Q00535	18
Metabolism of water soluble vitamins and cofactors	0.2752091904398402	0.903382256363984	0.3663230538120336	1.0	0.6609118281569589	38	Q99707,Q9NRN7,P34896,O00764,P50747,P78417,Q9NVE7,O00763	8
Negative regulation of flt3	0.7439327940261453	0.9007166364695726	0.3677390008990659	1.0	0.6617386708887165	2	P22681	1
Pd 1 signaling	0.7439327940261362	0.9007166364695384	0.3677390008990842	1.0	0.6617386708887165	2	Q06124	1
Signalling to ras	0.5154320104781986	0.8932364300381407	0.3717305728680733	1.0	0.6671839632515291	5	P12931	1
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein	0.314074157795028	0.8917018288576518	0.3725527730229809	1.0	0.667792389517198	22	Q16222,O95394,O60547,Q06210,Q9NR45	5
Amyloid fiber formation	0.7248784281687698	0.8864019473486087	0.3754009702314977	1.0	0.6720260891968004	3	Q9UJY4	1
Condensation of prophase chromosomes	0.3988497286324907	0.8789262196740975	0.3794412811663916	1.0	0.6758495069415341	10	Q86XI2,P62805,P06400	3
Interleukin 20 family signaling	0.7223778400249027	0.8772145027375078	0.3803701402507768	1.0	0.6758495069415341	3	Q06124,P40763	2
Receptor mediated mitophagy	0.5704360803917414	0.8768522490604245	0.3805668953111345	1.0	0.6758495069415341	4	P12931	1
Insulin processing	0.4557050350214611	0.8761287714324325	0.3809600332181295	1.0	0.6758495069415341	7	Q96KP1,O00471	2
Signaling by hippo	0.4826298707568969	0.8743129723687212	0.3819478366607187	1.0	0.6767332182886068	6	Q9UDY2	1
Tp53 regulates transcription of dna repair genes	0.2862887595178862	0.8724717846829013	0.3829510541610275	1.0	0.677641942190192	31	P50750,P38398,Q9H3P2,Q92759,P23193,Q9NYV4,P18615,Q9NVI1,Q15369,Q8IXH7,P43246	11
Degradation of the extracellular matrix	0.4045055901063669	0.8685237945910474	0.3851076519906198	1.0	0.6805866688632181	9	P17655	1
Telomere maintenance	0.2744145630642986	0.8433116053714969	0.3990541939170655	1.0	0.7016449058440007	43	Q9Y265,Q15054,P39748,P62805,Q8WVB6,P35244,P40937,P27694,P09884,P12004,P49643,O00743,P49642,Q9BUR4,P35250	15
Post translational protein modification	0.2267480815694064	0.8382103159045301	0.4019125943451496	1.0	0.7048771641941582	403	P43686,P28070,P12004,Q9P000,P48556,P61086,P47755,P38398,Q96RU2,Q86SZ2,Q9NZJ0,Q14258,Q13309,O43242,P13639,P50542,Q9H2P9,P53618,Q96JB2,P85037,Q9NXR7,P25788,Q6GQQ9,Q99627,O15027,Q9BUF5,Q96FW1,Q9BZG1,Q14527,Q06323,P84085,Q16222,Q9UL46,Q9UBT2,Q9UPU5,Q15369,O60547,P45974,A0AVT1,P54578,P62805,Q13200,P62333,P61201,Q86VX2,Q9UBE0,Q92538,P52739,Q13619,O60678,Q9NZ32,Q9GZS3,Q9Y6G9,Q9BZG8,Q86UV5,P22314,P25787,O43237,O75340,P61289,O95394,Q9BW61,P51148,P35998,Q9BTE7,P25789,Q92530,P42771,P49721,Q13564,Q96GG9,Q9BU89,Q9UNS2,P17980,P11142,P14735,P25786,Q13561,P68371,P51665,Q8N6T3,Q96IJ6,Q7L5N1,O00232,Q96MG7,P33908,P04350,Q06210,Q99497,Q9Y265,P61088,P52907,Q13885,O15498,P20618,Q9NR45,O00487,Q9UBI1,P28074,Q8IUR0,P68036,O95486,Q15436,Q15008,Q93034,Q96BN8,Q96K76,Q9Y5K5,Q9NXF7,Q9NZL9,Q9BT78,Q9BQC3,O00743,P34949,P49720,P35606,O00231,Q8TBC4,Q9UNM6,Q96ME1,O75832,P62195,Q14203,Q14166,Q99460,Q15018,Q99436,Q8NBJ7,Q9Y678,Q92905,Q9H0V9,Q12955,Q13616,P20336,Q12933,P15880,O00233,O94966,P18085,P63208,P28072,P60900,P55036,P61081,Q86VP6,Q9ULC3,Q15370,Q8NEZ5,O75935,Q9NWV8,P27694,Q13263,P28066,Q9UPT9,Q9UBF2,Q16186,Q9HC52,Q96EK6,Q13485,Q10471	160
Activation of irf3 irf7 mediated by tbk1 ikk epsilon	0.7112609381767356	0.8366133926181974	0.4028099151317312	1.0	0.7049895805950491	3	Q6SZW1	1
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism	0.5603985056039832	0.8347969541881287	0.4038320410733704	1.0	0.7049895805950491	4	P30154,P30153,P17612	3
Fbxw7 mutants and notch1 in cancer	0.710164039756231	0.8326299949181624	0.4050534370352521	1.0	0.705906494303554	3	Q13616	1
Mrna decay by 5 to 3 exoribonuclease	0.3974264574294238	0.8277386875831557	0.4078185042221347	1.0	0.7098301924873932	9	Q8IZH2,Q6P2E9,Q8IZD4	3
Nuclear receptor transcription pathway	0.5577208772248923	0.823646014830799	0.4101407221610476	1.0	0.7129741861969406	4	P11474	1
Intra golgi traffic	0.3964155724028625	0.8219472824386512	0.4111069010924413	1.0	0.7137559513941631	9	Q96JB2	1
Interleukin 21 signaling	0.7221530802738135	0.8172435223938741	0.4137892751138921	1.0	0.7157425678127977	2	P40763	1
Interleukin 9 signaling	0.7221530802738135	0.8172435223938741	0.4137892751138921	1.0	0.7157425678127977	2	P40763	1
Transcriptional regulation by tp53	0.2732253769754455	0.8145000093817969	0.4153585668493949	1.0	0.7157425678127977	125	P50750,P55212,Q9H3P2,Q9UIV1,P06744,P12004,Q9UQ84,P27348,P42575,P38398,Q92547,Q92597,P35244,Q16539,P19784,P23193,Q9NYV4,P18615,Q00535,P31946,P35250,O14727,P30154,Q04917,P42771,P40937,Q92600,Q92759,P54646,Q9NVI1,Q8IXH7,Q99873,P27694,O75175,Q96S44,Q15369,P43246	37
Nicotinamide salvaging	0.7190416925949012	0.8054772072263422	0.4205443540561611	1.0	0.7185188685247984	2	Q8NCW5	1
Rac3 gtpase cycle	0.2698112908905604	0.804986759554897	0.4208273203986683	1.0	0.7185188685247984	34	Q9UQB8,Q96AC1,O00161,O15498,Q9Y6W5,Q13177,Q16512,Q9H0H5,Q14739	9
Mhc class ii antigen presentation	0.2801363531934512	0.8002048088332105	0.4235921441105419	1.0	0.7185188685247984	55	O95487,P61163,P55735,Q14203,Q9H0H5,P04350,Q9NZ32,P47755,Q07866,Q9Y6G9,Q13885,Q9UJW0,P52907,O43237,Q9BXS5,P33176,O95239,Q14204,O43747,O94979,O95486,Q15436,P50570,P47756,O75935,Q9BUF5,Q99661,Q9Y496,P09496,Q13561,P68371	31
Ddx58 ifih1 mediated induction of interferon alpha beta	0.33943033791728	0.7990723210622425	0.424248478087001	1.0	0.7185188685247984	16	O15111,Q15366,Q12933,P09429,Q14258,P61086	6
Deadenylation of mrna	0.3390673502346784	0.7966441740402378	0.4256577146182825	1.0	0.7191429848440909	16	Q92600,O75175,Q9UIV1,Q9H074,P06730,Q14240,P60842	7
Runx2 regulates osteoblast differentiation	0.4884911383758272	0.7706157680751425	0.4409347121260751	1.0	0.7350684826999226	5	P12931	1
P38mapk events	0.5445672166219641	0.7693311828143917	0.4416967301690651	1.0	0.7352591975030435	4	P12931	1
Pp2a mediated dephosphorylation of key metabolic factors	0.690438917946949	0.7617724040853002	0.4461958533138856	1.0	0.7411508530334455	3	P30154	1
Irak1 recruits ikk complex	0.6896824283128927	0.7590862133580569	0.4478009857329428	1.0	0.7411508530334455	3	P61088	1
Budding and maturation of hiv virion	0.4324754749805359	0.7578803251615969	0.4485226296688269	1.0	0.7414572657922475	7	Q8WUX9,Q9NP79,Q99816	3
Tp53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain	0.4317110729310956	0.7540505797928164	0.4508188508806863	1.0	0.743859552738628	7	O75175,Q9UIV1	2
Metalloprotease dubs	0.4567692497047181	0.7507164806650246	0.4528233024150117	1.0	0.7439873084063058	6	O00487,Q15018,Q9NXR7,P38398	4
Platelet aggregation plug formation	0.4566109968561563	0.749972446544974	0.4532712996785886	1.0	0.7439873084063058	6	P41240,P12931,Q05397	3
Integrin signaling	0.4566109968561563	0.749972446544974	0.4532712996785886	1.0	0.7439873084063058	6	P41240,P12931,Q05397	3
Rhov gtpase cycle	0.3226197753009506	0.7300235742168826	0.4653757748720877	1.0	0.7535236537595201	17	O00401,Q13177,O43396,P16333,Q16512,Q8IW35	6
Nade modulates death signalling	0.6806925813862222	0.7273583893770601	0.4670064378198699	1.0	0.7544913093593435	3	P42575	1
Cd163 mediating an anti inflammatory response	0.6975731176104608	0.725541384167745	0.4681199660052211	1.0	0.7544913093593435	2	Q16539	1
Displacement of dna glycosylase by apex1	0.5329487332507792	0.7220724574707701	0.4702499307252354	1.0	0.7565604240538714	4	P29372	1
Regulation of tp53 activity	0.2700657148296704	0.7195962694302787	0.47177360961387	1.0	0.7576040663144648	53	P38398,Q92547,P30154,P27694,P42771,P35244,P40937,Q16539,P19784,Q96S44,Q9UQ84,Q00535,P35250	13
Telomere c strand synthesis initiation	0.4498497850873776	0.7183472518500255	0.4725432019993261	1.0	0.7576040663144648	6	P49642,P49643,P09884	3
Diseases associated with glycosaminoglycan metabolism	0.5286696180250988	0.704856557545589	0.4808995075167261	1.0	0.765671796530087	4	O95340	1
Synthesis of ip3 and ip4 in the cytosol	0.5284338156399946	0.703911018636807	0.4814881890853368	1.0	0.7657269013992354	4	Q13572,Q01970	2
Hats acetylate histones	0.2845692748688091	0.6969458805856038	0.4858366633459581	1.0	0.7717543318897864	23	Q96EB1,Q9Y265,P62805,Q9UPT9,Q6IA86,O95163,Q9H9T3,Q9Y230,Q9P2N6,Q01658,O14929	11
Enos activation	0.5259857198772002	0.6941143949793336	0.4876104718137291	1.0	0.7730944883326311	4	O95865,P35270	2
Raf activation	0.3170203860443986	0.6929219563749731	0.488358529894636	1.0	0.7730944883326311	17	P30154,Q02750,P12931,P30153,P31946	5
Deadenylation dependent mrna decay	0.2562694684888101	0.6915102693426203	0.4892449294156908	1.0	0.7736115474284724	41	Q96C86,Q8IZD4,Q9Y2L1,Q15477,Q8IZH2,Q92600,O75175,Q969T7,Q9UIV1,Q9H074,Q6P2E9,P06730,Q14240,Q9Y450,P60842,Q9GZS3,P26196	17
Transcriptional regulation of pluripotent stem cells	0.6860609831985197	0.6836815159013484	0.4941762979349744	1.0	0.7796251640937981	2	P40763	1
Signaling by bmp	0.6860609831985093	0.6836815159013111	0.4941762979349979	1.0	0.7796251640937981	2	Q7Z3T8	1
Signaling by vegf	0.259122967507935	0.6816159371106044	0.4954818348479635	1.0	0.7807127328277889	33	Q9UQB8,P05771,O14786,Q13464,Q05397,P12931,Q9Y6W5,Q16539,Q13177,P17612,P16333,Q16512,O43865,Q13685	14
Small interfering rna sirna biogenesis	0.5226445748889186	0.6808040313582566	0.4959954988587545	1.0	0.7807127328277889	4	Q9UPY3	1
Estrogen dependent nuclear events downstream of esr membrane signaling	0.6667849620657023	0.6790306746407654	0.4971184262017019	1.0	0.7812218510944231	3	O14980	1
P130cas linkage to mapk signaling for integrins	0.6657329598506128	0.6754151006223551	0.4994120742028376	1.0	0.7816392826141807	3	P12931,Q05397	2
Chaperone mediated autophagy	0.4387768867013218	0.6673005375951132	0.5045801830690473	1.0	0.7868824313866825	6	P11142,O60664,Q99497	3
Darpp 32 events	0.361819810664568	0.6665206861227346	0.5050783460192294	1.0	0.7868824313866825	10	P30154,Q08209,Q00535,P17612,P30153	5
Clec7a dectin 1 induces nfat activation	0.6804604853764765	0.6636000331219266	0.506946336100272	1.0	0.787190827517501	2	O43865	1
Interleukin 2 family signaling	0.6612079396868246	0.6599310607428361	0.5092980705736811	1.0	0.7899550320233752	3	P40763	1
Rhoh gtpase cycle	0.2782182198791812	0.6493623593364531	0.5161041875704007	1.0	0.7993232895432846	23	Q99707,Q9Y6M7,Q13464,Q9BZH6,P11182,Q16512,P41240	7
Dna repair	0.2603352203600705	0.637788428044484	0.5236114134001673	1.0	0.8060475367240106	120	P43246,P62805,P61201,O94782,Q7L5N1,P12004,Q9UQ84,Q13619,Q6P6C2,P38398,Q92547,Q9UNS1,Q9Y265,Q15054,P61088,P35244,Q86WJ1,Q92905,P23193,P29372,Q99504,Q9NZJ0,Q14258,P35250,P28340,P39748,P40937,Q92759,Q9NVI1,Q9NXR7,Q99627,P27695,Q9C0B1,Q9UNS2,Q9BT78,P27694,P13010,Q86W56,O14757,O00213,P60510,P52701	42
Pecam1 interactions	0.4568426274620581	0.632146122591549	0.5272913991710424	1.0	0.8082470402704898	5	P12931	1
Activation of nmda receptors and postsynaptic events	0.2700312482586194	0.6317894332987474	0.5275244792503486	1.0	0.8082470402704898	25	Q9BUF5,P49593,P12931,P54646,P04350,P68371,Q9NUP9	7
Dna double strand break repair	0.2601509270097906	0.6194823574445928	0.5355986408696793	1.0	0.8173186065698484	55	P62805,P12004,Q9UQ84,Q9UNS1,Q92547,Q15054,P61088,P38398,P35244,Q99504,P35250,P28340,P39748,P40937,Q9NXR7,P27694,P13010,O14757,O00213,P60510	20
Mitotic metaphase and anaphase	0.2401913122496503	0.6191600978905519	0.5358108954792205	1.0	0.8173186065698484	139	P51665,P53990,Q13200,P62333,P43686,Q9UNM6,P28070,Q8NC56,O00232,O75832,P04350,P62195,P48556,P63151,Q2NKX8,Q9Y6G9,Q15691,Q13885,P25787,O43237,P61289,Q99986,P20618,O00233,Q9P258,P35998,P30153,O14980,O43242,P30154,P25789,Q92530,O00487,P28074,P49721,P55036,Q92674,Q15008,P25788,Q8WUX9,Q96EA4,Q14739,Q9BUF5,P17980,Q06323,P14635,P28066,O75122,P25786,Q9UL46,Q7Z5K2,O60566,P68371,P49720	54
Synthesis of pips at the golgi membrane	0.3629126292719158	0.6022934838068438	0.5469787975654141	1.0	0.8234473836986953	8	Q9UBF8	1
Mapk3 erk1 activation	0.6434635113552627	0.6003425351689078	0.548277976670146	1.0	0.8236088736501541	3	Q06124	1
Kinesins	0.2956592199473959	0.5959255980807078	0.551224931670129	1.0	0.8262395396617335	18	Q9BUF5,Q13885,Q9NQT8,Q9Y496,Q9H0H5,P68371,P04350,Q07866	8
Creatine metabolism	0.639783924844439	0.5882272232767387	0.5563797869727778	1.0	0.8286698307470117	3	Q14353	1
Diseases of mismatch repair mmr	0.6395004074124472	0.5872973521532525	0.5570040191449719	1.0	0.8286698307470117	3	P43246	1
Aryl hydrocarbon receptor signalling	0.6383442265795217	0.5835107956204849	0.5595494917428001	1.0	0.8286698307470117	3	Q15185,P08238	2
Downregulation of tgf beta receptor signaling	0.395585420104294	0.5790491941123741	0.5625559798809492	1.0	0.8286698307470117	7	O14980,Q9Y3F4,Q9Y5K5	3
Nostrin mediated enos trafficking	0.6549471064094727	0.574744577504904	0.5654640544446339	1.0	0.8286698307470117	2	O00401	1
Signaling by alk in cancer	0.2486856841460134	0.5738139840713927	0.5660936847058857	1.0	0.8286698307470117	32	P62877,P40763,P26038,Q14203,Q9HC35,Q07866,P33176,P49589,Q13616,P26641,P63208,O94979,P67936,P10644,P35579,P31939,P62753,Q9NR09,P06753,Q86WB0	20
Bmal1 clock npas2 activates circadian gene expression	0.6348584835519981	0.5721483837722119	0.5672214526962851	1.0	0.8286698307470117	3	Q86X55	1
Signaling by alk	0.4174501003209233	0.572066375356854	0.5672770078944818	1.0	0.8286698307470117	6	P40763	1
Copi dependent golgi to er retrograde traffic	0.2464902775250927	0.5662080313882497	0.571252370903087	1.0	0.8318975517260973	46	Q8N6T3,Q9NQT8,Q92538,Q9H0H5,P04350,Q07866,Q9Y678,Q13885,O95239,P18085,O43264,P53618,P48444,Q9BUF5,Q9UBF2,P84085,Q9Y496,O15260,P68371,P35606	20
Carnitine metabolism	0.414806181481722	0.5605841464007298	0.5750810615432387	1.0	0.8343123546921948	6	O43772,O00763	2
Nuclear events stimulated by alk signaling in cancer	0.3219283932168673	0.5578313324049389	0.5769595650299242	1.0	0.8343123546921948	12	P63208,Q13616,P40763	3
Smac xiap regulated apoptotic response	0.6275820350457992	0.5486963899874903	0.5832138240253508	1.0	0.8395849008364946	3	O14727	1
Activation of caspases through apoptosome mediated cleavage	0.6275820350457992	0.5486963899874903	0.5832138240253508	1.0	0.8395849008364946	3	O14727	1
Signaling by pdgfra transmembrane juxtamembrane and kinase domain mutants	0.4867502023165318	0.5428659185772489	0.5872221230788417	1.0	0.8435976861693962	4	P40763	1
Cytosolic iron sulfur cluster assembly	0.3504871083087996	0.5390941344276137	0.5898219026790517	1.0	0.8464526163057625	8	P18074,P28340,Q9Y5Y2,O76071	4
Srp dependent cotranslational protein targeting to membrane	0.2605500069926771	0.5350479562882539	0.5926166963255866	1.0	0.8488554059016594	89	P61247,P62847,P46782,P62244,P62750,P05388,P42766,P62899,P15880,O76094,P62081,P61011,P46781,P08865,P46778,P62910,P08708,P47914,P18124,P62701,P09132,P62277,P62861,Q9Y3U8,Q9UHB9,P62841,P62269,P84098,P62854,P62906,P23396	31
Glycosaminoglycan metabolism	0.3252400986802107	0.5348918413386334	0.5927246502858909	1.0	0.8488554059016594	11	Q9UHD1,O95340,O43252	3
Smooth muscle contraction	0.3357865479559684	0.5281931084671361	0.5973653121047886	1.0	0.8537320179201839	10	P67936,P60660,Q13177,Q9Y490,Q16512	5
Signaling by cytosolic fgfr1 fusion mutants	0.3841131270482819	0.5265020097323333	0.5985394560137307	1.0	0.8537607638207954	7	P40763,Q92614	2
Formation of xylulose 5 phosphate	0.620548401337601	0.5263846629230076	0.5986209697122653	1.0	0.8537607638207954	3	Q00796	1
Uptake and actions of bacterial toxins	0.3824702290075313	0.5191210866878674	0.6036763044410276	1.0	0.8574312977774924	7	P13639,Q02750,Q16881,P08238,Q8WUM4	5
Pi3k akt signaling in cancer	0.3142493242398937	0.5164851741005475	0.6055155911706731	1.0	0.8582795353824311	12	Q96B36,P12931,Q06124	3
Signaling by wnt in cancer	0.3454836229587749	0.5143582660348384	0.6070015318814279	1.0	0.8586244801024906	8	Q13363,P30154,P49841,P30153	4
Rna polymerase ii transcription	0.1883787731019828	0.5071647220853046	0.6120392456000181	1.0	0.8613424006305753	321	P55212,P43686,P28070,Q9UIV1,P06744,P12004,Q9UQ84,P42575,P27348,P31350,P48556,P38398,Q92547,Q92597,P35244,Q16539,P18615,Q9NQG5,Q13309,Q00535,O14727,O43242,P11802,P54646,P25788,Q14739,Q06323,Q9UL46,Q96S44,Q15369,P43246,P50750,P11474,P62805,Q13200,P62333,P62258,Q9GZS3,Q9H944,Q13243,Q06124,P25787,P61289,P06400,P13984,P35998,P30153,P31946,Q00534,P30154,P25789,P42771,P49721,O94992,P51003,Q8IYB3,O00232,P12931,P19784,P23193,Q71SY5,Q9H814,Q99873,Q9UHY1,O75175,O43809,P49720,Q9H3P2,Q9UNM6,O75832,P62195,Q14353,Q96P16,Q9NYV4,Q13616,O00233,P35250,P63208,Q04917,P55036,P40937,Q92600,Q92759,Q9NVI1,Q8IXH7,P27694,P28066	87
Glycogen breakdown glycogenolysis	0.4005204979597853	0.4999628744991937	0.6171012188977409	1.0	0.8675827919803438	6	P06737,Q93100,Q96G03	3
Infectious disease	0.1888086605213977	0.4981798088172631	0.6183573125409016	1.0	0.8675835593213463	349	P43686,P62847,P28070,P61247,O00505,P62244,P62191,P62750,P59998,Q99816,P48556,P42766,Q9BXS5,Q16539,Q9Y6W5,P18615,P42566,P62899,Q14204,P08238,P78362,P62081,O14980,O43242,O43747,P18074,O14818,P08708,O00629,P13639,P47914,P18124,P62701,P30419,P25788,Q8WUX9,P62841,P62269,Q9BUF5,Q9NP79,Q06323,P62942,Q9UL46,Q15369,O00410,P50750,P62805,Q13200,P62333,Q9UQB8,Q9Y6G9,P25787,Q02750,O43237,P61289,P06400,P12268,P13984,P35998,P25789,P39748,Q92530,P49721,Q9Y3U8,Q99961,P20839,P17980,P25786,P62854,P68371,P62906,Q05397,Q96SB4,P51665,P46782,O00232,P05388,P04350,Q13885,P22681,O75446,P07437,P12931,P23193,P20618,P46781,O00487,P28074,O00401,Q13177,Q15185,Q15008,P61160,P62277,P62861,Q93034,Q9UN37,Q99873,Q9UI12,P13010,P00558,O43148,O15145,P49720,O00231,Q9H3P2,Q9UNM6,Q9Y2Z0,P43487,P16333,O75832,P62195,Q99460,Q99436,P15880,O00233,O15144,P12956,O43865,P63208,P08865,P28072,P46778,P62910,P55036,P60900,Q92759,P35579,Q86VN1,Q8IXH7,Q15370,Q14974,Q8WX92,Q13263,P28066,P84098,Q13464,P23396,P06733	139
Organelle biogenesis and maintenance	0.2547640826829747	0.4934871749940694	0.6216683995504411	1.0	0.8704617306775173	91	P11474,P50991,O94927,P62258,Q86X55,P17987,Q92538,P04350,Q9H0F7,Q15691,Q13885,P07437,Q16539,Q9BW83,P48643,P18085,P30153,P36405,P50990,P54646,Q96CS2,O00471,Q8NCM8,Q8IW35,Q9H6D7,O75935,Q9BUF5,O60645,Q9Y496,Q96KP1,P68371,Q13561,P78371,Q9Y547	34
Nucleotide excision repair	0.2459200619021096	0.4875710809549216	0.6258536835698139	1.0	0.8708047826454745	59	Q9Y265,Q15054,P61088,Q86WJ1,P28340,P35244,P61201,Q92905,P40937,Q92759,Q9UNS2,P27694,P23193,Q7L5N1,P12004,Q13619,Q99627,P35250	18
Disassembly of the destruction complex and recruitment of axin to the membrane	0.3973437996391513	0.4868311754229734	0.6263779755162322	1.0	0.8708047826454745	6	P30154	1
Beta catenin phosphorylation cascade	0.3973437996391513	0.4868311754229734	0.6263779755162322	1.0	0.8708047826454745	6	P30154	1
Signaling by ctnnb1 phospho site mutants	0.3973437996391513	0.4868311754229734	0.6263779755162322	1.0	0.8708047826454745	6	P30154	1
Signaling by tgfb family members	0.2579955137196417	0.4833249398975557	0.6288650344386166	1.0	0.8708047826454745	22	P50750,O14980,Q9Y3F4,P22681,Q7Z3T8,P61081,P62942,Q13485,Q9Y5K5	9
Apoptotic cleavage of cellular proteins	0.261195194547245	0.4815793997351212	0.6301047631298657	1.0	0.8708047826454745	21	P55212	1
Ripk1 mediated regulated necrosis	0.3255464625277301	0.4772081425285658	0.633213913507156	1.0	0.8713211336871473	10	Q16543,O15294,Q9UNE7,Q12933,P07900,Q8WUM4	6
Senescence associated secretory phenotype sasp	0.2817228428025192	0.4770077129195124	0.6333566293823145	1.0	0.8713211336871473	17	Q00534,P42771,P11802,P40763	4
Keratinization	0.3719469446234359	0.47277549292675	0.6363733601822208	1.0	0.8713211336871473	7	P04632,Q14126,Q08554,P15924,P07384	5
Formation of the cornified envelope	0.3719469446234359	0.47277549292675	0.6363733601822208	1.0	0.8713211336871473	7	P04632,Q14126,Q08554,P15924,P07384	5
Copii mediated vesicle transport	0.2349516413290303	0.4722012144731337	0.636783172955151	1.0	0.8713211336871473	32	Q5H9R7,O95487,Q8IUR0,Q15363,Q9H0V9,O15155,O15498,O95486,Q86SZ2,Q15436,O00743,P55735,O15027	13
Signaling by erbb2	0.2889174052176247	0.4642375578308458	0.6424775554344473	1.0	0.8782433052526273	14	P12931,Q93034	2
Cell cell communication	0.2373880874730014	0.4592199245855529	0.6460762439008438	1.0	0.8789120014982815	30	Q13418,Q06124,O00401,Q15404,Q96AC1,P12931,P16333	7
Sensory perception	0.244067684370497	0.4590368031941417	0.6462077375418342	1.0	0.8789120014982815	26	Q6IBS0,P52907,P15311,P35579,P23634,P20336,P50579,P30419,P26038,P53582,Q14651,P47756,P47755	13
Platelet homeostasis	0.302924171309194	0.4580959512361607	0.6468835075949997	1.0	0.8789120014982815	12	P23634,P30154,Q16539,Q06124	4
Sensory processing of sound by outer hair cells of the cochlea	0.2951437620493168	0.4564665662762983	0.6480545076170396	1.0	0.8789120014982815	13	Q6IBS0,P15311,P35579,P23634,Q14651,P26038	6
Rab geranylgeranylation	0.2560250391236438	0.4503020623900136	0.6524926521093799	1.0	0.8836635411381528	21	P61006,P62820,P51149,P61106,P20339,P61026,Q92696,Q14964,P20336,P51148,P61019,P20338,P61020,Q9ULC3,P51153,Q9BZG1,Q9NP72,Q9H0U4,Q9UL25,Q15286	20
Hiv infection	0.223594349615568	0.4489078102363064	0.6534981616959781	1.0	0.8836932088687296	135	P50750,P51665,Q9H3P2,Q13200,P62333,P43686,Q9UNM6,P28070,P43487,O00232,O75832,Q99816,P62195,Q99460,P48556,Q99436,P25787,P61289,P23193,P18615,P13984,P20618,P12956,O00233,P35998,O14980,O43242,O00487,P25789,P39748,Q92530,P28074,P49721,P63208,P28072,P60900,P55036,Q92759,Q13177,Q15008,P30419,P25788,Q8WUX9,Q93034,Q15370,Q9UN37,Q9UI12,Q8IXH7,Q14974,Q9NP79,Q06323,P17980,P28066,P25786,Q9UL46,P13010,Q15369,O43148,P49720,O00231	60
Protein methylation	0.3656316940046309	0.4457860506925264	0.6557517989845261	1.0	0.8837296813020533	7	P13639,P11142,O60678	3
Antigen activates b cell receptor bcr leading to generation of second messengers	0.4594305020055824	0.4455283289106562	0.6559379920492838	1.0	0.8837296813020533	4	P16333	1
Purinergic signaling in leishmaniasis infection	0.5928034842266654	0.4421388813798276	0.6583887101067472	1.0	0.8837296813020533	3	Q9Y2Z0	1
Inflammasomes	0.5928034842266654	0.4421388813798276	0.6583887101067472	1.0	0.8837296813020533	3	Q9Y2Z0	1
The nlrp3 inflammasome	0.5928034842266654	0.4421388813798276	0.6583887101067472	1.0	0.8837296813020533	3	Q9Y2Z0	1
Interferon gamma signaling	0.284613708896567	0.4417905327736594	0.6586407899718631	1.0	0.8837296813020533	14	Q14258,P42224,Q06124,P29372	4
Runx1 regulates transcription of genes involved in differentiation of myeloid cells	0.612632233976355	0.438743799525603	0.660847186594103	1.0	0.8858300794113001	2	P05771	1
Arachidonic acid metabolism	0.4561961747929602	0.4345295406463743	0.6639039480391888	1.0	0.8882045074444908	4	P09960,Q15185	2
Transcription coupled nucleotide excision repair tc ner	0.2316452686251792	0.4319335503994388	0.6657897094581302	1.0	0.8890061627740444	50	Q15054,P28340,Q9UNS2,P27694,P35244,P61201,Q92905,P40937,Q92759,P23193,Q7L5N1,P12004,Q13619,Q99627,P35250	15
Cellular responses to stimuli	0.1654438996497113	0.4268264429960224	0.6695057448616959	1.0	0.8922439145601386	329	O60884,P41091,P43686,P62847,P28070,P61247,P62244,P62191,P62750,P48556,P47755,P42766,P35244,Q16539,P62899,Q96B36,Q13309,P62081,O14980,O43242,P08708,P11802,P47914,P51858,P25788,P62841,P62269,Q9BUF5,Q06323,Q9UL46,Q15369,P62805,Q13200,P62333,P62258,Q92598,Q99543,Q9NZ32,Q9UL15,Q9Y6G9,P25787,O43237,P61289,P06400,O95817,P35998,Q00534,P25789,Q92530,P42771,P49721,Q0VDF9,Q9Y3U8,P17980,P11142,P25786,Q13561,P32119,P62854,P68371,P62906,P51665,P36543,Q8N6T3,P40763,P46782,Q86X55,O43301,O00232,P05388,P04350,Q06210,Q53FT3,P34932,P52907,Q13885,Q13451,P19784,P20618,P25685,P46781,O00487,P28074,P30041,Q15185,Q15008,P62277,P62861,Q9UI12,P21283,P49720,O00231,P54652,Q99615,Q9UNM6,Q92616,O75832,P62195,Q14203,Q99460,Q99436,Q13616,P15880,O00233,O95816,P63208,P08865,P28072,P46778,P62910,P55036,P60900,Q15370,O75935,P27694,Q9Y2L1,P28066,P84098,Q9NYB0,Q9HC52,P23396,O95757	122
Transport and synthesis of paps	0.5871672387917839	0.4258222916959882	0.6702373422641605	1.0	0.892358388255366	3	O95340	1
Rho gtpase effectors	0.2338840322496275	0.4243769670097577	0.6712909157662814	1.0	0.8929009100952847	118	O43684,P05771,P62805,P46940,P62258,O15143,P59998,P16333,P55735,P27348,Q16512,P04350,Q9HD26,Q2NKX8,Q07866,Q9UQB8,Q9Y6G9,Q15691,Q16513,Q13885,O43237,Q16539,Q9Y6W5,P12931,Q14247,O15144,Q14204,Q9P258,P30153,P31946,O14980,O43264,P30154,Q04917,O00401,Q13177,P35579,Q92674,P61160,P50748,Q7Z406,Q96EA4,O60610,Q13526,Q9BUF5,Q13464,Q92747,O75122,O15145,O60566,P68371,Q05397	52
Assembly and cell surface presentation of nmda receptors	0.3028142546883143	0.4228798146517848	0.672382950779018	1.0	0.8934934980544259	11	P68371,Q9BUF5,Q9NUP9,P04350	4
Gap junction trafficking and regulation	0.2952407301167351	0.4204173699785356	0.6741805810798494	1.0	0.895021674401875	12	P12931,Q9BUF5,P68371,P04350	4
Interferon alpha beta signaling	0.3171518931961749	0.409096081348739	0.6824691519119575	1.0	0.902557289896962	9	Q13325,P61221,Q9Y3Z3,Q06124	4
Mitotic prometaphase	0.2414618270090726	0.4067085938816809	0.6842220278545605	1.0	0.9035135856944952	88	O94927,P62258,Q8TD19,P04350,Q9HC35,Q2NKX8,Q9Y6G9,Q15691,O43237,P07437,P19784,Q9P258,P30153,O14980,P30154,Q15003,Q15021,Q92674,Q96CS2,Q96CW5,Q96EA4,O75935,Q9BUF5,P14635,O75122,Q13561,O60566,Q7Z5K2,P68371	29
Smad2 smad3 smad4 heterotrimer regulates transcription	0.4467151535171506	0.4029940603171349	0.6869525940459527	1.0	0.9035135856944952	4	P50750	1
Fceri mediated mapk activation	0.3210723192020051	0.40055960309324	0.6887443927084411	1.0	0.9035135856944952	8	P63000,P62993,Q13177,P19174,Q16512,P28482,P07948	7
Metabolism of ingested semet sec mesec into h2se	0.5992532669570667	0.3992450110934995	0.6897126804428204	1.0	0.9035135856944952	2	P23526	1
Epha mediated growth cone collapse	0.2971643842320536	0.3966869156288509	0.6915983500486458	1.0	0.9051031437189664	11	P60660,Q13464,P12931,P35579,Q7Z406,O75116	6
Ngf stimulated transcription	0.5760314610043792	0.3944453550374077	0.6932522638879783	1.0	0.9055525791050908	3	Q00535	1
Apoptotic execution phase	0.2182931849305747	0.3792192173578254	0.7045250820945281	1.0	0.9174493940413804	33	P55212,Q9UJU6,Q13464,O00273,P09429,P15924,P26583,O76075,O00429,Q9UDY2,P55210,Q05397	12
Signaling by rho gtpases miro gtpases and rhobtb3	0.113999956572197	0.3785589895377049	0.7050153809493096	1.0	0.9174493940413804	258	Q99707,P62805,P61201,P62258,O00161,Q92974,O43396,P16333,P27348,Q16512,P04350,Q9H0H5,Q9HD26,Q92888,Q15208,Q08378,Q9UQB8,Q9Y6G9,Q9Y6M7,Q2NKX8,Q15691,Q16513,Q13885,O43237,Q16539,Q9Y6W5,O15498,P12931,P11182,P15924,O15144,Q9UDY2,P41240,Q9P258,P30153,P31946,O14980,P30154,Q04917,Q02952,O00401,Q13492,Q13177,Q92674,P61160,Q9NYL9,Q96EA4,Q8IYB3,O60610,Q8IW35,Q14739,Q9NQW6,Q9BUF5,Q96AC1,Q13464,Q9BZH6,O75122,O60664,P68371,O60566,P78371,P12277,Q05397	63
Phase i functionalization of compounds	0.2667575278093258	0.3730220679444767	0.7091320195915576	1.0	0.9196256036951682	16	P07099,P11766	2
Hiv elongation arrest and recovery	0.2421594790431036	0.3726573394649973	0.7094034910762699	1.0	0.9196256036951682	21	P50750,Q9H3P2,P23193,P18615,Q15369,Q8IXH7	6
Rho gtpases activate rocks	0.2832486641628607	0.3650647097579031	0.7150631031168757	1.0	0.9207998500902896	12	P60660,Q13464,P35579,Q16512,Q7Z406,P35580,O75116,P23528	8
Biotin transport and metabolism	0.312765198993668	0.3647910872304042	0.7152673586817571	1.0	0.9207998500902896	8	P50747	1
Nephrin family interactions	0.3063341929053679	0.3620023831872035	0.7173502495302633	1.0	0.9207998500902896	9	O00401	1
Activation of nima kinases nek9 nek6 nek7	0.3869051353962439	0.3614606047402675	0.7177551498643888	1.0	0.9207998500902896	5	Q8TD19	1
Tetrahydrobiopterin bh4 synthesis recycling salvage and regulation	0.5855631611698849	0.3607978979617399	0.7182505342961882	1.0	0.9207998500902896	2	P35270	1
Chromosome maintenance	0.2181924590482933	0.3592836187137137	0.7193829277260129	1.0	0.9209898224204842	48	Q9Y265,Q15054,P39748,P62805,Q8WVB6,P35244,P40937,P27694,P09884,P12004,Q92674,P49643,O00743,P49642,Q9BUR4,P35250	16
Signaling by pdgfr in disease	0.3625490914054043	0.3527622600614361	0.7242666792026928	1.0	0.9242685983680932	6	P40763	1
Host interactions of hiv factors	0.2296190436530106	0.3527175361841934	0.7243002113116099	1.0	0.9242685983680932	97	P50750,P51665,Q13200,P62333,P43686,Q9UNM6,P28070,P43487,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,O14980,O43242,O00487,P25789,Q92530,P28074,P63208,P49721,P28072,P60900,P55036,Q13177,Q15008,P25788,Q93034,Q15370,Q9UI12,P17980,Q06323,P28066,P25786,Q9UL46,Q15369,P49720,O00231	44
Rhoj gtpase cycle	0.2378133225009308	0.3503275133203493	0.7260929193162731	1.0	0.9245993416195588	21	Q9Y6M7,O00401,O00161,Q13177,Q16512	5
Constitutive signaling by ligand responsive egfr cancer variants	0.3611617513058005	0.3478295094603258	0.7279682264908165	1.0	0.9245993416195588	6	Q16543,P07900,P22681	3
Signaling by egfr in cancer	0.3611617513058005	0.3478295094603258	0.7279682264908165	1.0	0.9245993416195588	6	Q16543,P07900,P22681	3
Constitutive signaling by egfrviii	0.3611617513058005	0.3478295094603258	0.7279682264908165	1.0	0.9245993416195588	6	Q16543,P07900,P22681	3
Suppression of phagosomal maturation	0.3406619600421461	0.3459579858905096	0.7293742896664304	1.0	0.924766301210098	7	P20339,P31146,Q9UI12,Q14974	4
Signaling by tgf beta receptor complex	0.236110866626638	0.3418555079998953	0.7324596339750289	1.0	0.9269773023383608	21	P50750,O14980,Q9Y3F4,P22681,P61081,P62942,Q13485,Q9Y5K5	8
Phenylalanine metabolism	0.5551610396175023	0.3389172368956298	0.7346720789701653	1.0	0.928926635989724	3	Q7L266	1
Trans golgi network vesicle budding	0.2067384551370546	0.3273971524807701	0.7433675198906278	1.0	0.938204486291185	34	O43747,Q9Y5X3,Q13492,Q9Y5X1,O00161,Q9BXS5,O14976,P11142,O00443,Q92538,P09496,O00203,P50570,P51148,Q14677	15
Downregulation of erbb2 signaling	0.3539870826003263	0.3228799441414397	0.7467861657606012	1.0	0.9399439718407566	6	Q9UNE7,Q16543,P07900,Q93034	4
Flt3 signaling in disease	0.3014774645795366	0.3189213049191977	0.7497861882697703	1.0	0.9411485124330812	8	Q06124,P22681	2
Diseases of glycosylation	0.2384175786554279	0.3132301502431124	0.7541058135515619	1.0	0.9448542468977864	19	O75340,Q96L58,O95340,P36871,P34949,Q06210	6
Ret signaling	0.3299578590331925	0.3069309307258215	0.7588959453279354	1.0	0.949135019405617	7	Q13322,P17612,P12931,Q06124	4
Leishmania infection	0.2011767416188254	0.2972454923728997	0.7662790926083818	1.0	0.9540254290364998	42	Q9UQB8,O00401,Q9Y2Z0,Q92747,P12931,Q9Y6W5,Q16539,P35579,O15143,Q05397,P59998,P16333,P61160,O15144,O15145,P08238,O43865	17
Metabolism of vitamins and cofactors	0.2032058770946006	0.2919748881270324	0.7703058241775911	1.0	0.9546909225041968	46	Q99707,Q9NRN7,P34896,O00764,P50747,P78417,Q9NVE7,O00763	8
Recognition and association of dna glycosylase with site containing an affected purine	0.4088572037884199	0.2887690727130085	0.7727581007077422	1.0	0.9546909225041968	4	P62805,P29372	2
Rhoc gtpase cycle	0.1964830895633048	0.2886623864994108	0.7728397491061163	1.0	0.9546909225041968	35	Q9NQW6,Q16513,Q07960,Q13464,Q16512,Q9H0H5,Q9UDY2,O60610,Q92888,Q14739	10
Dual incision in tc ner	0.192967048631285	0.2800431340930596	0.7794444120692483	1.0	0.9600643293045464	37	Q15054,P27694,P35244,P40937,Q92759,P23193,P12004,Q13619,P35250	9
Interleukin 37 signaling	0.4039853830911142	0.2755636147269579	0.7828832591858674	1.0	0.9602784990842635	4	P40763	1
Signaling by receptor tyrosine kinases	0.1875333242007172	0.2754011353617308	0.7830080719075561	1.0	0.9602784990842635	119	P51452,P36543,P40763,P61201,Q96P70,P16333,Q9BUB5,Q16512,P62330,Q9UQB8,Q9Y6I3,Q06124,P22681,Q02750,Q16539,Q9Y6W5,P12931,P42566,P13984,P16949,P41240,P46109,P30153,Q00535,P31946,P30154,Q13177,Q93034,O60610,Q9UI12,Q99961,Q13464,P21283,O14757,Q05397,P42224	36
Asparagine n linked glycosylation	0.1877530785009934	0.2723840031439701	0.7853267715051111	1.0	0.961393893643794	117	O95487,Q8N6T3,Q96IJ6,O15155,P62191,P61163,Q92538,P55735,P33908,P04350,Q9NZ32,Q06210,Q14203,P47755,Q9Y678,Q9Y6G9,Q5H9R7,Q13885,P52907,Q9H0V9,O43237,O75340,O15498,Q86SZ2,Q12955,O95394,Q9Y223,Q14204,O14579,Q9NR45,P18085,Q8IUR0,P53618,Q96JB2,O95486,Q15436,P48444,P47756,O15027,O75935,Q9BUF5,Q15363,P84085,Q9UBF2,Q16222,Q96EK6,O00743,O60547,P34949,Q13561,P68371,P35606	52
Activated pkn1 stimulates transcription of ar androgen receptor regulated genes klk2 and klk3	0.5274110270519248	0.2722973162306208	0.7853934196265149	1.0	0.961393893643794	3	Q16512	1
Cholesterol biosynthesis	0.240372692907247	0.2552676065187432	0.7985164175777164	1.0	0.9707620866138512	15	Q14739	1
Signal attenuation	0.5185185185185284	0.252809967111177	0.8004150652059936	1.0	0.971881562473518	3	Q13322,P28482	2
Glycogen metabolism	0.2709725345414766	0.2500724394058904	0.8025313291241396	1.0	0.971881562473518	10	P06737,P13807,Q96G03,Q93100,P36871,Q16851	6
The activation of arylsulfatases	0.515359838101423	0.2461132658142565	0.8055945542302161	1.0	0.971881562473518	3	Q8NBJ7	1
Ncam signaling for neurite out growth	0.2753352042407293	0.2447476554087179	0.8066518262568627	1.0	0.971881562473518	9	P18433,Q13813,P01111,P12931,P62993,Q01082,P28482,Q05397	8
Nef mediated cd4 down regulation	0.3292834890965773	0.2446451318391516	0.8067312155255106	1.0	0.971881562473518	6	P53680,O95782,P63010,Q9UI12,O94973	5
Nef mediated cd8 down regulation	0.3292834890965773	0.2446451318391516	0.8067312155255106	1.0	0.971881562473518	6	P53680,O95782,P63010,Q9UI12,O94973	5
Nuclear signaling by erbb4	0.391338025252453	0.2430054256458987	0.8080011943593242	1.0	0.971881562473518	4	P61201,P12931	2
Disorders of transmembrane transporters	0.197207186316137	0.2400287083201832	0.8103080010372912	1.0	0.971881562473518	74	P51665,Q13200,P62333,Q9UNM6,P43686,P28070,O00232,O75832,P62195,Q99460,P48556,Q99436,P25787,P61289,P20618,O00233,P35998,P28072,O00487,P25789,P28074,Q92530,P55036,P49721,O43242,Q15008,P25788,P28066,P17980,Q06323,P25786,Q9UL46,P49720,O00231	34
Hiv transcription elongation	0.2007637507051081	0.2388983914929843	0.8111843728562658	1.0	0.971881562473518	26	P50750,Q9H3P2,Q92759,P23193,P18615,Q15369,Q8IXH7	7
Ros and rns production in phagocytes	0.2792759281130227	0.2388173054387085	0.8112472506525039	1.0	0.971881562473518	8	P21283,P36543	2
Signaling by nodal	0.5339141257000707	0.2357174472691713	0.8136519303776115	1.0	0.971881562473518	2	Q13485	1
Signaling by activin	0.5339141257000707	0.2357174472691713	0.8136519303776115	1.0	0.971881562473518	2	Q13485	1
Rsk activation	0.5339141257000704	0.2357174472691701	0.8136519303776124	1.0	0.971881562473518	2	Q15418	1
Metabolic disorders of biological oxidation enzymes	0.3433694914146051	0.2298693589481277	0.8181932868069925	1.0	0.9737473875954124	5	P48506,P23526,P48637	3
Defects in vitamin and cofactor metabolism	0.2538250030118863	0.2287253815007941	0.8190823660880449	1.0	0.9737473875954124	11	Q99707	1
Cell junction organization	0.2251090999048745	0.2254693790993786	0.821614144040697	1.0	0.9737473875954124	17	Q15404	1
Repression of wnt target genes	0.3838729763387273	0.2249886805620186	0.8219880801351778	1.0	0.9737473875954124	4	Q13363,Q04726,P56545	3
Regulation of ifng signaling	0.3830366025346922	0.2230267340283475	0.823514699733813	1.0	0.9737473875954124	4	Q06124	1
Insulin receptor signalling cascade	0.3208722741433112	0.2209049380151277	0.8251664524211875	1.0	0.9738999661981398	6	Q13322,Q06124,P62993,P28482,Q99570	5
Rac2 gtpase cycle	0.1788745677459852	0.2208521334583064	0.8252075690434311	1.0	0.9738999661981398	35	P46940,O95292,Q13112,Q14126,Q6IAA8,P51149,P60953,P52565,Q16512,Q9H0H5,Q68EM7,O96013,Q9NSV4,Q9Y6W5,P02786,Q86XL3,Q13177,P49257,Q9Y2U8,Q13505,Q96RT1,Q7L576,Q8WUW1,P05556,P42166,Q14739,Q9Y512,P50402,Q07960,Q9BSJ8,P11274,Q9Y2A7,Q9UH62,P43121	34
Rho gtpases activate formins	0.1872062334838994	0.219634889451767	0.8261555169574462	1.0	0.9741026756610706	61	O14980,Q9Y6G9,P30154,Q9BUF5,Q15691,O60566,O43237,P12931,O75122,Q92674,O60610,P04350,P68371,Q96EA4,Q9P258,Q2NKX8,P30153	17
Cdc42 gtpase cycle	0.1829080348470016	0.2188215883189881	0.8267890293418494	1.0	0.9741026756610706	33	Q9UQB8,O00401,Q07960,O00161,O15498,Q13177,Q16512,Q9H0H5,Q14739	9
Signal transduction by l1	0.2585030615417539	0.2108004868833502	0.8330429586025985	1.0	0.978468673534872	10	P19784,Q16512	2
Cd209 dc sign signaling	0.3357578650508995	0.21050920611097	0.8332702672029935	1.0	0.978468673534872	5	Q13177,Q16512	2
Formation of tc ner pre incision complex	0.1878750215069956	0.210436774091048	0.8333267935966311	1.0	0.978468673534872	29	Q9UNS2,P61201,Q92905,Q92759,P23193,Q7L5N1,Q13619,Q99627	8
Fceri mediated ca 2 mobilization	0.334475241357835	0.2073602015395594	0.8357285616390331	1.0	0.9796782965825884	5	O43865,Q08209,P62993,P19174	4
Diseases of dna repair	0.2467089737255327	0.2073010487045182	0.835774755188764	1.0	0.9796782965825884	11	P38398,Q9UQ84,P43246	3
Deactivation of the beta catenin transactivating complex	0.2625288640662219	0.204792567696331	0.8377341940689684	1.0	0.9811429289858596	9	O14980,Q9HCK8,Q9UBL3,Q04726,Q13363	5
Josephin domain dubs	0.5168014934660953	0.2017931131889356	0.8400784656794089	1.0	0.9822969169395565	2	P55072	1
Factors involved in megakaryocyte development and platelet production	0.1709624889232832	0.1964609416857198	0.844249400923516	1.0	0.9841583777950748	43	Q9BUF5,P52907,Q9NQT8,Q9Y496,Q9H4M9,Q13572,Q9H0H5,P68371,P04350,P47755,Q00535	11
Resolution of sister chromatid cohesion	0.1709411161846072	0.1960364366669155	0.8445816469355707	1.0	0.9841583777950748	61	O14980,Q9Y6G9,P30154,Q9BUF5,Q15691,O60566,P14635,O43237,O75122,Q92674,Q7Z5K2,P04350,P68371,Q96EA4,Q9P258,Q2NKX8,P30153	17
Interleukin 4 and interleukin 13 signaling	0.2350162659434283	0.1922209947450922	0.8475691011173776	1.0	0.9868074959934422	12	P11142,Q07820,P42224,P40763	4
Irf3 mediated activation of type 1 ifn	0.5090230242688338	0.1876583838329846	0.8511444554905228	1.0	0.9884719642755484	2	Q9UHD2	1
Rhoa gtpase cycle	0.1639309598497627	0.1835118438769175	0.8543964265076944	1.0	0.990135367818406	47	Q9NQW6,Q16513,Q07960,Q13464,O00161,O15498,Q92974,Q16512,Q9H0H5,Q9UDY2,O60610,Q92888,Q14739	13
Fgfr1 mutant receptor activation	0.2593516409765155	0.1793871967880972	0.8576336838094851	1.0	0.990135367818406	8	Q92614,P40763	2
Signaling by type 1 insulin like growth factor 1 receptor igf1r	0.3207723450638455	0.1757868215718152	0.8604614232781385	1.0	0.9917912318351854	5	Q99570,P62993,Q06124,O14654	4
Gaba synthesis release reuptake and degradation	0.3598310323948975	0.1732358795840856	0.8624660221496194	1.0	0.9932733688423118	4	P20336,P11142	2
The phototransduction cascade	0.3571993223700163	0.1681614098717093	0.8664562990270428	1.0	0.9939256148029963	4	P50579,P30419	2
Growth hormone receptor signaling	0.3170855903614157	0.1679427221928385	0.8666283399693275	1.0	0.9939256148029963	5	P40763	1
Rac1 gtpase cycle	0.1445380402865246	0.1668406907834772	0.8674954007664861	1.0	0.9940950612431873	47	Q9UQB8,Q16513,Q96AC1,O00401,Q07960,O00161,O15498,Q9Y6W5,Q13177,Q16512,Q9H0H5,Q14739	12
Regulated necrosis	0.2062789352401619	0.1648994279008198	0.8690231427050235	1.0	0.995020698606746	16	Q16543,O15294,P42574,Q9UNE7,P09429,Q12933,Q8WUX9,P07900,Q8WUM4	9
Rho gtpases activate nadph oxidases	0.2788367285790371	0.1574338883951578	0.8749029073767867	1.0	0.9984441106479928	7	Q16539,Q13526	2
Regulation of cholesterol biosynthesis by srebp srebf	0.1750828768239989	0.1561798141603193	0.8758912874438216	1.0	0.9987473261116844	23	O00763,Q86X55,Q03426,O95486,Q15436,Q01581,Q13907	7
Potential therapeutics for sars	0.1050705411599361	0.1506023462378226	0.8802894104746684	1.0	1.0	40	Q92769,O95983,P20839,P62877,Q13464,O75446,P07437,P62942,Q09028,P08238,O00422,P12268,Q15185,O75116,P07900,Q02790	16
Nicotinate metabolism	0.3472503534055506	0.1500363924866719	0.8807359031703044	1.0	1.0	4	Q8NCW5	1
Extra nuclear estrogen signaling	0.2004022798791137	0.1440919569566283	0.8854278558623487	1.0	1.0	14	O14980,P12931,Q99873	3
Constitutive signaling by aberrant pi3k in cancer	0.272277829865504	0.1429995863483485	0.886290507881945	1.0	1.0	7	P12931	1
G alpha i signalling events	0.1477062723710743	0.1401341274826807	0.8885540167924324	1.0	1.0	29	P30154,Q86YR5	2
Signaling by insulin receptor	0.1933770696657318	0.1364381186395027	0.8914749410990379	1.0	1.0	15	Q13322,P36543,Q15904,Q06124,P01111,P61421,P21283,P38606,P62993,P21281,Q93050,P28482,Q9UI12,Q99570	14
Gluconeogenesis	0.1669599256766492	0.1312895813723164	0.8955462333117561	1.0	1.0	20	P04075,P06744,P09104,P00558,P17174,P09972,P60174,P18669	8
Role of abl in robo slit signaling	0.3356164383561619	0.1309536663814593	0.8958119605405981	1.0	1.0	4	Q7Z460,O75122,Q01518	3
Myogenesis	0.2725631153969146	0.115150636260116	0.9083257248695352	1.0	1.0	6	Q16539	1
Met activates ptk2 signaling	0.3241960627588449	0.1143977113413015	0.908922528171692	1.0	1.0	4	P12931	1
Irs mediated signalling	0.3206724782067222	0.1097152776429633	0.9126351837582072	1.0	1.0	4	P62993,Q06124,Q99570	3
Downstream signaling of activated fgfr2	0.320672478206722	0.1097152776429627	0.9126351837582076	1.0	1.0	4	P62993,Q06124,P19174	3
Downstream signaling of activated fgfr1	0.320672478206722	0.1097152776429627	0.9126351837582076	1.0	1.0	4	P62993,Q06124,P19174	3
Downstream signaling of activated fgfr3	0.320672478206722	0.1097152776429627	0.9126351837582076	1.0	1.0	4	P62993,Q06124,P19174	3
Downstream signaling of activated fgfr4	0.320672478206722	0.1097152776429627	0.9126351837582076	1.0	1.0	4	P62993,Q06124,P19174	3
Interleukin 35 signalling	0.4234842946742138	0.1045101656829458	0.9167645014097504	1.0	1.0	3	P40763	1
Interleukin 27 signaling	0.4234842946742138	0.1045101656829458	0.9167645014097504	1.0	1.0	3	P40763	1
Early phase of hiv life cycle	0.2489582463867347	0.1004717578784404	0.9199698033108136	1.0	1.0	7	P39748,P13010	2
Dna methylation	0.3106191295590131	0.097426991322077	0.9223873107102992	1.0	1.0	4	P62805	1
Insulin receptor recycling	0.2058568847909245	0.0903309910088796	0.928024193548449	1.0	1.0	9	P21283,P36543	2
Pyroptosis	0.2543630311195671	0.0887084775251153	0.9293135950097098	1.0	1.0	6	P09429	1
Transferrin endocytosis and recycling	0.1930754834684939	0.0875009361115774	0.93027334137742	1.0	1.0	10	P36543,Q15904,P61421,P21283,P02786,P21281,Q93050,P38606,Q9UI12	9
Vegfr2 mediated cell proliferation	0.2528243672680488	0.0867873920396685	0.9308405095028356	1.0	1.0	6	P12931,O43865	2
Signaling by fgfr1 in disease	0.1896444167186512	0.0844145561523076	0.9327268344577851	1.0	1.0	10	Q16630,Q92614,P40763,P01111,P11274,P62993,P19174,Q9UBW7,P42224	9
Base excision repair ap site formation	0.249690928170896	0.0830202888695925	0.9338354071171888	1.0	1.0	6	P62805,P29372	2
Regulation of ifna signaling	0.3913581397584198	0.0778620980462325	0.9379377492211898	1.0	1.0	3	Q06124	1
Synthesis of prostaglandins pg and thromboxanes tx	0.3912231559290401	0.0777714323856341	0.938009871255394	1.0	1.0	3	P16152,Q15185	2
Chrebp activates metabolic gene expression	0.2533585181351326	0.0745862256566018	0.9405439339275016	1.0	1.0	5	Q13085,P53396,O00763	3
Sema4d induced cell migration and growth cone collapse	0.1856511402476549	0.0712403924285778	0.9432064345563048	1.0	1.0	9	P60660,Q13464,P35579,Q7Z406,O75116	5
Phosphorylation of emi1	0.376283846872089	0.0687268867808874	0.9452070162429403	1.0	1.0	3	P14635,P06493	2
Fcgr3a mediated il10 synthesis	0.174306205176181	0.0642184713064669	0.94879626977608	1.0	1.0	9	P10644,P13861,P12931,P19174,P17612,P07948,O43865,P07947	8
Chl1 interactions	0.2950246678144848	0.0451627310642856	0.9639776002245406	1.0	1.0	3	P11142	1
Dopamine neurotransmitter release cycle	0.2804563454276443	0.0438103578258796	0.9650555706617964	1.0	1.0	3	Q9NUP9	1
Uptake and function of anthrax toxins	0.244260762736608	0.0421106980606401	0.9664104519179626	1.0	1.0	3	Q02750	1