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b6d2066 verified
Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Neddylation 0.5320662431963482 4.216136178796268 2.4852371883321567e-05 0.0337632623268233 0.0085864944856879 85 P49720,P62333,Q15369,P61081,Q9UL46,O75832,Q9H0A8,P25789,P25787,P49721,P55036,Q06323,Q9Y3I1,P35998,P62877,Q9UBW8,Q9NZJ0,Q96GG9,Q14999,Q9UNM6,O00233,P20618,Q92905,Q13564,Q9UBI1,Q9NXF7,Q8NEZ5,Q99460,P25788,Q9P000,Q13309,P63208,P28074,Q99436,Q8TBC4,Q15291,Q9UNS2,Q9Y5A7,Q13616,O00231,Q92530,Q9BTE7,Q9BW61,P28072 44
Orc1 removal from chromatin 0.5664663871315342 4.136346563818821 3.528791200091419e-05 0.0475986575861693 0.0088680713232281 52 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q9UNM6,O00233,P20618,P49736,Q9UBD5,O43913,Q99460,P25788,P24941,Q13309,P63208,O43929,P28074,Q99436,Q13616,O00231,Q92530,P28072 29
Innate immune system 0.3445227621555626 4.107989768946761 3.991177796125456e-05 0.0536654995747486 0.0088680713232281 287 P16333,Q08554,P15924,P81605,P14923,Q01469,P67870,Q06124,P25787,P35222,P04080,P09972,P50570,O00161,P07437,P10619,P42575,P35237,Q99460,Q9BRF8,O15144,Q9Y315,P28074,P61160,P07355,Q92530,P42785,Q13510,Q8N2G8,Q9UL46,O75832,P47755,P20336,Q9Y6W5,Q6SZW1,Q15366,Q06323,P55036,P38606,P60953,O14727,Q99829,P12931,Q92820,Q13546,P12268,O95352,P07947,P07948,Q9Y2Z0,P17858,Q9P000,P51452,Q92747,Q96G03,Q99439,P13798,P07858,P30041,P36871,P49720,P25789,P20839,P17900,P49721,Q9BU76,P28482,P07602,P14174,Q13526,P00491,O15145,P13639,P53634,Q8TBC4,Q7Z434,Q8IV08,P28072,Q9UII4,Q9UQB8,P35998,P07384,O00233,Q9NQR4,Q9UBI1,P25788,P63172,Q14019,P63208,Q9Y6G9,P11279 91
Mitotic g1 phase and g1 s transition 0.5318552184802259 4.077173621057049 4.558645331331768e-05 0.0610583239228433 0.0088680713232281 79 P49720,P62333,Q13547,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,Q00534,P09884,Q14181,P12931,P20618,Q9NR33,P49736,P04818,P27694,P31350,P49643,O43913,Q9UBD5,Q99460,P07948,P63151,P56282,P25788,P24941,Q13309,P63208,P28074,O43929,P35244,Q99436,P04183,Q13616,P30154,O00231,Q92530,P14635,P06493,P28072,P11802 47
Transcriptional regulation by runx2 0.5309768515737748 3.798096789453359 0.0001458113882912 0.1825177029017108 0.0088680713232281 56 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q13951,Q9UNM6,O00233,P28482,P12931,P20618,Q99460,P07947,P25788,Q13309,P63208,P28074,Q99436,Q13616,Q9UNE7,O00231,Q92530,P14635,P06493,P28072,P11802 32
Scf skp2 mediated degradation of p27 p21 0.6061636092552201 3.741627671154269 0.0001828322545716 0.2232970280075819 0.0088680713232281 42 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P24941,Q13309,P63208,P28074,Q99436,Q13616,O00231,Q92530,P28072,P11802 25
Mitotic g2 g2 m phases 0.4792443942425967 3.7399767078784825 0.0001840373078887 0.2245896968914444 0.0088680713232281 91 P62140,P49720,P62333,P68371,Q9UL46,O75832,Q13561,Q14203,P25789,P25787,P49721,P55036,Q06323,P35998,Q9NVX0,P62877,O75935,Q9UNM6,Q9UIC8,O00233,Q96CW5,Q13409,O14974,Q13885,P07437,Q9BUF5,P21127,P20618,O95067,Q99460,P63151,P25788,P43034,P24941,P04350,P63208,P28074,Q99436,Q15691,Q9H6D7,Q13616,P30154,Q9Y570,Q96CS2,O00231,Q92530,P14635,P06493,P28072 49
Degradation of beta catenin by the destruction complex 0.5339013430574628 3.7289757500054086 0.0001922596508772 0.2333526661389759 0.0088680713232281 51 P49720,P62333,Q13547,Q9UL46,O75832,P25789,P25787,Q16537,P49721,P55036,Q06323,P35998,P62877,P35222,Q9UNM6,O00233,P20618,Q99460,P25788,P63208,P28074,Q99436,Q13616,P30154,O00231,Q92530,P28072 27
The role of gtse1 in g2 m progression after g2 checkpoint 0.5410812920085469 3.716355383851624 0.000202117240371 0.2437280598578548 0.0088680713232281 50 P49720,P62333,P68371,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,Q13885,Q9BUF5,P20618,O95067,Q99460,P25788,P04350,P28074,Q99436,Q15691,O00231,Q92530,P14635,P06493,P28072 28
Synthesis of dna 0.4826292007560894 3.6534627620969986 0.0002587273255603 0.3006524341318867 0.0097435179221896 86 P49720,P39748,P62333,P35249,Q9UL46,O75832,Q9BRX5,P25789,P25787,P49721,P55036,Q06323,Q15054,P35998,P62877,Q9UNM6,O00233,P09884,Q14181,P20618,P18858,Q9NR33,P49736,P35250,P27694,P40937,P49643,O43913,Q9UBD5,Q9UJX5,Q99460,Q9Y2S7,P56282,P40938,P25788,P24941,Q13309,P63208,P28074,O43929,P35244,Q99436,Q13616,O00231,Q92530,P49005,P28072 47
Hedgehog off state 0.5171245338262386 3.648027624429539 0.0002642612305749 0.3059819321514166 0.0097435179221896 53 P49720,P62333,P68371,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q9UNM6,O00233,Q13885,Q9BUF5,P20618,Q99460,P25788,P04350,P63208,P28074,Q99436,Q13616,O00231,Q92530,Q9Y496,P28072 28
Cyclin a cdk2 associated events at s phase entry 0.5803884618981408 3.644500618500641 0.0002679114913481 0.3094751286940392 0.0097435179221896 44 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P24941,Q13309,P63208,P28074,Q99436,Q13616,O00231,Q92530,P28072,P11802 25
Mapk6 mapk4 signaling 0.532545244841611 3.6331284249739375 0.0002800055648162 0.3209237615528995 0.0099222484763081 50 P49720,P62333,Q9UL46,O75832,P04792,P25789,P25787,P49721,P55036,Q06323,P35998,P60953,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P06493,P28072 23
Dna replication 0.4694955826920026 3.5900478020922075 0.0003306173249093 0.3668124994992806 0.0108788843577316 90 P49720,P39748,P62333,P35249,Q9UL46,O75832,Q9BRX5,P25789,P25787,P49721,P55036,Q06323,Q15054,P35998,P62877,Q9UNM6,O00233,P09884,Q14181,P20618,P18858,Q9NR33,P49736,P35250,P27694,P40937,P49643,O43913,P48556,Q9UBD5,Q99460,Q9UJX5,Q9Y2S7,O60684,P56282,P40938,P25788,P24941,Q13309,P63208,P28074,O43929,P35244,Q99436,Q13616,O00231,Q92530,P49005,P28072 49
Interleukin 1 family signaling 0.51730060678323 3.563531554996133 0.0003658986868588 0.3969556404309758 0.0114925451190675 51 P49720,P62333,Q9UL46,O75832,P25789,Q06124,P25787,P49721,P55036,Q06323,P35998,P62877,Q9UNM6,O00233,P20618,P40763,Q99460,Q02750,P25788,P63208,P28074,Q99436,Q13616,O00231,Q92530,P28072 26
Tcr signaling 0.5325762588599129 3.5549090100494554 0.0003781099146653 0.4070508993129306 0.0116121756015006 49 P16333,P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,P41240,Q99460,P25788,P63208,P28074,Q99436,Q13616,O00231,Q92530,Q8N8S7,P28072 25
Dna replication pre initiation 0.4998911171742903 3.5110846291915423 0.0004462822979705 0.4603852401832519 0.0119126738236711 63 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P09884,Q14181,P20618,Q9NR33,P49736,P27694,P48556,P49643,O43913,Q9UBD5,Q99460,O60684,P56282,P25788,P24941,O43929,P28074,Q99436,P35244,O00231,Q92530,P28072 34
Biological oxidations 0.5273505193809371 3.504194296285805 0.0004579910709436 0.4690506485306022 0.0119126738236711 49 Q969Z3,P48506,Q16851,P48637,O75223,Q8WUX2,P21266,O43708,P78417,Q15185,P07099,P11766,P48507,Q96DG6,Q9UI30,O95861,O43169,O00170,P21964,P14550,Q99707,Q9HBK9,O95340,Q96KP4,Q9Y5N5,Q96IU4,O60701 27
Antigen processing ubiquitination proteasome degradation 0.4371860094345994 3.494537099660914 0.0004748846038826 0.4813087169010184 0.0119126738236711 102 O95376,P49720,P62333,Q15369,P52888,Q9UL46,O75832,Q92990,Q8TDB6,P25789,P25787,P49721,Q9UII4,P55036,Q06323,Q7Z6J8,Q9Y3I1,P35998,P62877,P55786,Q14999,Q5VTB9,O00233,P20618,P60604,Q8NEZ5,Q9UJX5,Q99460,O95352,P68036,P25788,Q13309,Q7Z7E8,P63208,P28074,Q99436,Q8TBC4,Q9C0C9,Q13867,Q13616,Q9UNE7,O00231,Q92530,P28072 44
Regulation of runx2 expression and activity 0.5413293519167994 3.4914366385851903 0.0004804304023786 0.4852708089423779 0.0119126738236711 47 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q13951,Q9UNM6,O00233,P20618,Q99460,P25788,Q13309,P63208,P28074,Q99436,Q13616,Q9UNE7,O00231,Q92530,P28072 26
Regulation of runx3 expression and activity 0.5898234447634969 3.489466210909016 0.0004839862404324 0.48779528415202 0.0119126738236711 40 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q13951,Q9UNM6,O00233,P12931,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 22
Interleukin 1 signaling 0.5370445467555223 3.4510901934269915 0.0005583269512277 0.5378303888331493 0.0130780990948591 47 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q9UNM6,O00233,P20618,Q99460,Q02750,P25788,P63208,P28074,Q99436,Q13616,O00231,Q92530,P28072 24
Clec7a dectin 1 signaling 0.51312367230128 3.4412462166855144 0.0005790413688369 0.550880799196731 0.0133372528622101 50 P49720,P62333,P61081,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P12931,P20618,Q99460,P25788,P63208,P28074,Q99436,Q8TBC4,Q13616,O43865,O00231,Q92530,P28072 26
Tnfr2 non canonical nf kb pathway 0.5530784527772353 3.4012409174944556 0.0006708068098073 0.6044056999417868 0.0147151589072026 44 P49720,P62333,P61081,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,P48556,Q99460,P25788,P63208,P28074,Q99436,Q8TBC4,Q13616,O00231,Q92530,P28072 25
Degradation of gli1 by the proteasome 0.5570717335298168 3.3763090893683825 0.000734653365968 0.6378381537498773 0.0156726612708949 43 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q9UNM6,O00233,P20618,Q99460,P25788,P63208,P28074,Q99436,Q13616,O00231,Q92530,P28072 23
Negative regulation of notch4 signaling 0.5630902943213689 3.371177075682037 0.0007484773110557 0.644696508105067 0.0156726612708949 42 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q9Y6A5,Q9UNM6,O00233,P20618,Q99460,P25788,P63208,P28074,Q99436,Q13616,O00231,Q92530,P28072 24
Adaptive immune system 0.3576721216231064 3.359134214198777 0.0007818708398672 0.660733092802131 0.0156901920240341 199 P16333,Q8TDB6,Q06124,P25787,Q9UJW0,P50570,O00161,P10619,P60604,Q8NEZ5,Q99460,P47756,P28074,O43237,P62942,Q92530,Q8N8S7,Q9Y496,Q9UL46,O75832,P47755,P78310,P55036,Q06323,P62877,P60953,P55786,Q14999,Q5VTB9,Q13409,P12931,O95352,P07947,P07948,P04350,Q13867,Q7Z7E8,P07858,P49720,Q15369,P68371,Q13561,Q14203,P25789,P49721,Q9Y3I1,P55735,Q96FJ2,Q9BUF5,P20618,P68036,P52732,P53634,Q99436,Q8TBC4,Q9C0C9,Q13616,P30154,O00231,O43865,P28072,O95376,P62333,P52888,P61081,Q92990,Q16537,Q9UII4,Q14807,Q7Z6J8,P35998,O75935,Q9UNM6,Q9NZ32,O00233,Q13885,O94855,P41240,P48556,Q9UJX5,P25788,Q13309,P63208,Q9Y6G9,Q9UNE7,O95487 86
Signaling by the b cell receptor bcr 0.5118149238491702 3.351949460929697 0.0008024466611167 0.6702519737519246 0.0156901920240341 49 P16333,P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P07948,P25788,P63208,P28074,Q99436,P62942,Q13616,O43865,O00231,Q92530,P28072 26
Dectin 1 mediated noncanonical nf kb signaling 0.553943975433085 3.348453552320606 0.000812639010526 0.6748678890404944 0.0156901920240341 43 P49720,P62333,P61081,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P63208,P28074,Q99436,Q8TBC4,Q13616,O00231,Q92530,P28072 24
Fceri mediated nf kb activation 0.5394296043556812 3.339681612862461 0.0008387448886277 0.6863983790665786 0.0156901920240341 45 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P07948,P25788,P63208,P28074,Q99436,Q13616,O00231,Q92530,P28072 23
Cdt1 association with the cdc6 orc origin complex 0.5654566695686176 3.335931029351608 0.00085014252254 0.6913034934891664 0.0156901920240341 41 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q9UBD5,O43913,Q99460,P25788,O43929,P28074,Q99436,O00231,Q92530,P28072 23
Regulation of pten stability and activity 0.5577001673789963 3.3238453954368743 0.0008878540205496 0.7069931477726745 0.015730952005124 42 P49720,P62333,Q9UL46,O75832,P25789,P67870,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,Q9UNE7,O00231,Q92530,P19784,P28072 23
Switching of origins to a post replicative state 0.4819979618480019 3.3047081533853735 0.0009507534625339 0.7314092137967804 0.0164242660652735 61 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q9UNM6,O00233,P20618,P49736,Q9UBD5,O43913,Q9UJX5,Q99460,P25788,P24941,Q13309,P63208,O43929,P28074,Q99436,Q13616,O00231,Q92530,P28072 30
C type lectin receptors clrs 0.4826214675006149 3.2918482245891334 0.0009953131094559 0.747465576716627 0.0169817619415825 55 P49720,P62333,P61081,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P12931,P20618,Q99460,P07948,P25788,P63208,P28074,Q99436,Q8TBC4,Q13616,O43865,O00231,Q92530,P28072 27
Transcriptional regulation by runx3 0.5244452138996973 3.264472712669745 0.0010966802612548 0.7805089452436127 0.0180504474237487 46 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q13951,P35222,Q9UNM6,O00233,P12931,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 23
Metabolism of polyamines 0.555856199920301 3.252460186945267 0.0011441062263193 0.7944487737170183 0.0180504474237487 41 P49720,P62333,Q9UL46,O75832,P52788,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P19623,P28072 22
Hedgehog on state 0.5279847058235823 3.233634106014966 0.0012222593684647 0.8155165619983982 0.0183330871918612 45 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,Q9Y496,P25098,P28072 23
Serine biosynthesis 0.91350342252645 3.2248731942192137 0.0012602847736959 0.8249724708129194 0.0183338269183986 2 Q9Y617 1
Formation of apoptosome 0.9066583696328588 3.194286025134366 0.0014017715765557 0.8560957856448779 0.0183829795059227 2 O14727 1
Signaling by mapk mutants 0.9066583696328588 3.194286025134366 0.0014017715765557 0.8560957856448779 0.0183829795059227 2 Q99956 1
Fc epsilon receptor fceri signaling 0.4731060363978842 3.1893256404897503 0.0014260513684616 0.8608509421455548 0.0183829795059227 54 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P28482,P20618,Q99460,P07948,P25788,P63208,P28074,Q99436,Q13616,O43865,O00231,Q92530,P28072 25
Cellular response to hypoxia 0.5333856334607984 3.163452315284459 0.0015590989059421 0.8842538804963175 0.0190679175930275 43 P49720,P62333,Q15369,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 22
Pyrimidine salvage 0.8963907902924741 3.1481900446559683 0.0016428484754165 0.896923475814257 0.01940527002586 2 P04183 1
Regulation of hmox1 expression and activity 0.4904606961079772 3.1390229251884674 0.0016951218563372 0.9041188809261334 0.0198530373343904 49 P49720,P62333,Q9UL46,O75832,P25789,P67870,P25787,P49721,P55036,Q06323,P35998,P62877,Q9UNM6,O00233,P20618,Q99460,P25788,Q13309,P63208,P28074,Q99436,Q13616,O00231,Q92530,P19784,P28072 26
Degradation of dvl 0.5484677191841882 3.135865265358617 0.001713479041649 0.906524801939843 0.0198993952567986 40 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 21
G1 s dna damage checkpoints 0.5352084955183972 3.1239384245485144 0.0017844779621358 0.9152755928405988 0.0203813929229073 42 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,O14757,P20618,Q99460,P25788,P24941,P28074,Q99436,O00231,Q92530,P28072 22
Downstream signaling events of b cell receptor bcr 0.5157043882759886 3.1186308258207087 0.0018169345957581 0.9189984948939124 0.020581996814244 45 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P63208,P28074,Q99436,P62942,Q13616,O00231,Q92530,P28072 23
Regulation of ras by gaps 0.5314534488513687 3.0901820520846464 0.0020003384463285 0.937164580587604 0.0217674624631969 42 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q9UNM6,P21359,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 22
Apc c mediated degradation of cell cycle proteins 0.462660701130071 3.0846921664117484 0.0020376293012382 0.9403270573571952 0.0219171612280867 59 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,O60566,Q9UJX5,Q99460,P25788,P24941,Q13309,P63208,P28074,Q99436,O43684,Q13616,O00231,Q92530,P14635,P06493,P28072 29
Tyrosine catabolism 0.8820784069695105 3.0834996994942956 0.0020458131681788 0.940999527510922 0.0219171612280867 2 O43708 1
Signaling by notch4 0.5161518571654711 3.0628589806175417 0.0021923334647735 0.951835395861538 0.0227804875813311 44 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q9Y6A5,Q9UNM6,O00233,P20618,Q99460,P25788,P63208,P28074,Q99436,Q13616,O00231,Q92530,P28072 24
Degradation of axin 0.5484646063224615 3.039514315407682 0.0023695994084764 0.9623217580852385 0.0240793116361359 38 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 20
Cross presentation of soluble exogenous antigens endosomes 0.5484646063224615 3.039514315407682 0.0023695994084764 0.9623217580852385 0.0240793116361359 38 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 20
Uch proteinases 0.4863154280914978 3.027483740317346 0.0024659898022281 0.96703163691183 0.0248089528349373 48 P49720,Q16186,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P85037,P20618,Q99460,P25788,P28074,Q99436,Q9Y5K5,O00231,Q92530,P28072 23
Runx1 regulates transcription of genes involved in differentiation of hscs 0.5300206494616981 3.02438764426242 0.0024913699112492 0.9681707416664804 0.0248089528349373 41 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q13951,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 21
Copi mediated anterograde transport 0.4572886416958923 3.0190108461865894 0.0025360145219865 0.9700798667885762 0.0248089528349373 55 Q13561,Q14203,P47755,P84085,O75935,Q9UJW0,Q92538,Q13409,Q96FJ2,Q9H0U4,Q9BUF5,Q9BVK6,O15155,P61923,Q13190,P47756,Q8N6T3,P04350,O43237,Q96JB2,Q9Y6G9,Q99747,Q15363 23
Signaling by hedgehog 0.4557924956458823 3.0087428726164416 0.00262331031428 0.9734885478100052 0.0253525514289166 59 P49720,P62333,P68371,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q9UNM6,O00233,Q13885,Q9BUF5,P20618,Q99460,P25788,P04350,P63208,P28074,Q99436,Q13616,O00231,Q92530,Q9Y496,P25098,P28072 29
Transport to the golgi and subsequent modification 0.4416728351483512 2.9883244078836637 0.0028051163475346 0.9793928718868826 0.026552539673239 77 Q13561,P33908,Q9H0V9,Q14203,P47755,P84085,O75935,Q9UJW0,P55735,Q92538,Q13409,Q96FJ2,Q9BUF5,Q9BVK6,O15155,O15027,P61923,Q13190,P47756,O00743,P04350,P53634,O43237,Q96JB2,Q9Y6G9,Q99747,Q15363,O95487 28
Cilium assembly 0.4540708920135599 2.983872650571764 0.0028462520809651 0.980534836843536 0.0267586420128829 55 P68371,Q13561,Q14203,Q92973,Q9Y547,Q9NVX0,O75935,O00471,Q92538,Q13409,Q96FJ2,P07437,Q9BUF5,Q96KP1,O60645,P43034,Q9H0F7,P04350,P48643,Q9H6D7,Q15691,Q96CS2,Q9Y496,Q8IW35 24
S phase 0.4088854673706718 2.9728893189279697 0.0029501081158938 0.9831444472833676 0.0275476311903056 97 P49720,P39748,P62333,P35249,Q9UL46,O75832,Q9BRX5,P25789,P25787,P49721,P55036,Q06323,Q15054,P35998,P62877,Q9UNM6,O00233,P09884,Q14181,P20618,P18858,Q9NR33,P49736,P35250,P27694,P40937,P49643,O43913,Q9UBD5,Q9UJX5,Q99460,Q9Y2S7,P56282,P40938,P25788,P24941,Q7Z5K2,Q13309,P63208,P28074,O43929,P35244,Q99436,Q13616,O00231,Q92530,P49005,P28072,P11802 49
Phase ii conjugation of compounds 0.572890047693346 2.943250205832393 0.0032478580825348 0.9888447468939192 0.0290288656861487 32 P48506,Q16851,P48637,O75223,Q8WUX2,P21266,O43708,P78417,P48507,Q9UI30,O95861,P14550,Q99707,Q9HBK9,O95340,Q96KP4,Q9Y5N5,Q96IU4,O60701 19
Class i mhc mediated antigen processing presentation 0.3513154099304423 2.937916334855593 0.003304261809824 0.9896839146829242 0.0290288656861487 123 O95376,P49720,P62333,Q15369,P52888,Q9UL46,O75832,P61081,Q92990,Q8TDB6,P25789,P25787,P49721,Q9UII4,P55036,Q06323,Q7Z6J8,Q9Y3I1,P35998,P62877,P55786,Q14999,Q5VTB9,P55735,Q9UNM6,O00233,O00161,P20618,O94855,P60604,P48556,Q8NEZ5,Q9UJX5,Q99460,O95352,P68036,Q12846,P25788,Q13309,Q7Z7E8,P63208,P28074,Q99436,Q8TBC4,Q9C0C9,Q13867,Q13616,Q9UNE7,O00231,Q92530,O95487,P28072 52
Stabilization of p53 0.5229101763648203 2.9110499954994893 0.0036021637397489 0.993175102842932 0.0303548188312993 40 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 20
Ptk6 regulates cell cycle 0.8413192283758566 2.8964387754185497 0.0037742428021951 0.9946243276372708 0.0310476401942484 2 P24941 1
Auf1 hnrnp d0 binds and destabilizes mrna 0.501454159308411 2.869431629017635 0.0041121022347592 0.996636058086222 0.0321623491722129 43 P49720,P62333,Q9UL46,O75832,P04792,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 21
Wnt mediated activation of dvl 0.835096453018051 2.8675042065122778 0.0041372330443829 0.9967513521948466 0.0321623491722129 2 P19784 1
Netrin mediated repulsion signals 0.8347853142501619 2.866054833034158 0.0041562224937727 0.996835844633058 0.0321623491722129 2 P12931 1
Defective cftr causes cystic fibrosis 0.5052550409655602 2.851599796756836 0.0043499829143149 0.9975819401490952 0.0326721542803441 42 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 20
Abc transporter disorders 0.5052550409655602 2.851599796756836 0.0043499829143149 0.9975819401490952 0.0326721542803441 42 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 20
Dissolution of fibrin clot 0.822962041070325 2.8107911449401186 0.0049419854184529 0.998937101960852 0.0363288502569252 2 P07355 1
Tcf dependent signaling in response to wnt 0.4329192883808083 2.75969974849675 0.0057854506765888 0.9996707559192636 0.0414274240157814 62 P49720,P62333,Q13547,Q9UL46,O75832,P25789,P67870,P25787,Q16537,P49721,P55036,Q06323,P35998,P62877,P35222,Q9UNM6,O00233,P20618,Q99460,Q9UBL3,P25788,P28074,Q99436,Q15291,P30154,O00231,Q92530,P19784,P28072 29
Developmental biology 0.2936967510238626 2.744954395711966 0.0060519307061934 0.9997726862382884 0.0418818501492814 275 P16333,Q08554,P15924,P62899,Q02487,P14923,P49720,Q9UL46,O75832,Q13322,P42766,P62081,P08708,P25789,P67870,Q06124,P04632,P25787,P49721,P55036,Q06323,P35998,P62877,P60953,P62847,O75116,P35222,P84098,P62910,P05388,Q7Z406,P62857,P18433,P50570,P07384,P28482,O00233,P62244,P12931,P62841,Q9BUF5,O75530,Q14195,P08134,Q99460,Q9UBL3,P25788,P24941,P62753,O15144,P04350,O15145,P28074,Q00535,P61160,Q71SY5,Q15291,Q9NPJ6,Q9Y5S9,Q92796,Q92530,Q8N8S7,P24468,P19784,P28072,P11802 66
Asymmetric localization of pcp proteins 0.5093986246216198 2.744195354450895 0.0060659427792622 0.9997770720681464 0.0418818501492814 39 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 20
Trna modification in the nucleus and cytosol 0.6273811308819093 2.7435696917792134 0.006077514618171 0.9997806302706128 0.0418818501492814 22 Q9UBP6,O75648,Q9H974,Q9UI30,Q96FX7,Q2VPK5,O60294,Q9NX74,Q96PZ0,Q7Z4G4,Q96BT7 11
Formation of the cornified envelope 0.9102654788786524 2.6840817804372965 0.0072729313458779 0.9999584211995376 0.04741127886794 7 Q08554,P15924,P04632,P14923 4
Keratinization 0.9102654788786524 2.6840817804372965 0.0072729313458779 0.9999584211995376 0.04741127886794 7 Q08554,P15924,P04632,P14923 4
Hsp90 chaperone cycle for steroid hormone receptors shr in the presence of ligand 0.5371232219720526 2.61582186771583 0.008901298198725 0.999995699035559 0.0537882206455325 31 O75935,Q9UJW0,O43237,Q13561,Q13451,Q9Y6G9,P54652,Q14203,Q13409,P47755,Q96FJ2,Q15185,Q9BUF5,P47756,P04350 15
Gdp fucose biosynthesis 0.7812694461730008 2.6129643418906445 0.0089760666792404 0.9999961248774772 0.0537882206455325 2 O60547 1
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.4267088887459266 2.612718214117271 0.0089825328862578 0.9999961596634184 0.0537882206455325 51 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q9UJX5,Q99460,P25788,Q13309,P28074,Q99436,O00231,Q92530,P28072 22
G2 m checkpoints 0.4040991743762557 2.605122121128595 0.0091841518706288 0.9999971009925572 0.0537882206455325 83 P49720,P62333,P35249,Q9UL46,O75832,Q9NWV8,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,Q9NXR7,O00233,O14757,P20618,P35250,P49736,P27694,P40937,O43913,Q9UBD5,O95067,Q99460,P40938,P25788,P24941,Q92547,Q04917,P28074,O43929,P35244,Q99436,O00231,Q92530,P38398,P14635,P06493,P28072 40
Er to golgi anterograde transport 0.4114522711847638 2.6038795192362847 0.009217515271563 0.9999972328109444 0.0537882206455325 76 Q13561,Q9H0V9,Q14203,P47755,P84085,O75935,Q9UJW0,P55735,Q92538,Q13409,Q96FJ2,Q9H0U4,Q9BUF5,Q9BVK6,O15155,O15027,P61923,Q13190,P47756,O00743,P04350,P53634,O43237,Q96JB2,Q9Y6G9,Q99747,Q15363,O95487 28
Hedgehog ligand biogenesis 0.4887222098738709 2.6026846400928485 0.009249699306556 0.9999973542907832 0.0537882206455325 40 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 20
Copi independent golgi to er retrograde traffic 0.5640043905197134 2.593967380384896 0.0094875487881931 0.9999981013891 0.0537882206455325 26 O75935,Q9UJW0,O43237,Q13561,Q9Y6G9,Q14203,Q13409,P47755,Q96FJ2,P43034,Q9BUF5,P47756,Q15102,P04350 14
Signaling by notch 0.4183476792210127 2.5852274954312047 0.0097314764389651 0.9999986491370328 0.054011648347991 58 P49720,P62333,Q13547,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,Q9Y6A5,Q9UNM6,Q92769,O00233,P20618,Q99460,Q9H488,P25788,P63208,P28074,Q99436,Q13616,O00231,Q92530,Q15363,P28072 28
Pten regulation 0.416302635156635 2.5826236154590614 0.0098052228641249 0.9999987812561756 0.0540388167142656 66 P49720,P62333,Q13547,Q9UL46,O75832,P25789,P67870,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,Q92769,O00233,P28482,P20618,O75530,Q93009,Q99460,P25788,P28074,Q99436,Q8WXI9,Q9UNE7,O00231,Q92530,P19784,P28072 29
Neutrophil degranulation 0.3232094309765954 2.5822946442049965 0.0098145752498413 0.999998797061119 0.0540388167142656 171 P36871,Q08554,P15924,P42785,Q13510,P14923,Q8N2G8,P11279,Q01469,P67870,P20336,P20839,P17900,P25787,Q9BU76,P35998,O14727,P04080,P07384,P09972,O00161,P28482,Q99829,P07437,P10619,P35237,Q92820,Q9NQR4,Q9UBI1,P12268,Q99460,P07602,Q9BRF8,O95352,P14174,P17858,Q9P000,P63172,P00491,Q14019,Q9Y315,P13639,Q96G03,P53634,Q99439,P61160,P13798,Q9Y6G9,P07355,P07858,P30041 51
Intra golgi and retrograde golgi to er traffic 0.4059180074629238 2.5706455177077965 0.010150917070121 0.9999992477930424 0.055448882968013 79 P68371,Q13561,P33908,Q14203,P40616,P47755,Q15102,Q14807,P84085,O75935,Q9UID3,Q9UJW0,Q9UP83,O14579,Q9NZ32,Q92538,Q13409,Q96FJ2,Q9H0U4,Q13885,Q9BUF5,Q9BVK6,P61923,P52732,P43034,Q13190,P47756,Q8N6T3,P04350,O43237,Q96JB2,Q9Y6G9,Q99747,Q07866,O95239,O60664,O43264,O15498,Q12756,Q15363,Q9Y496 41
Galactose catabolism 0.7713130056004985 2.5650346704753986 0.0103165495934249 0.9999994031053792 0.0559430324028774 2 P51570 1
Assembly of collagen fibrils and other multimeric structures 0.7632233976353562 2.525895159693781 0.0115403914635896 0.9999998920462596 0.0607979576691707 2 Q15149 1
Mapk family signaling cascades 0.3757904164907493 2.524324564523594 0.0115920848167594 0.9999998995734488 0.0607979576691707 98 O75608,P62140,P49720,P62333,P04792,Q9UL46,O75832,P10398,P25789,Q06124,P25787,P49721,Q16537,P55036,Q06323,P35998,P62877,P60953,Q9UNM6,P18433,P21359,Q99956,O00233,P28482,P12931,P30086,P20618,P41240,Q99460,Q02750,Q13555,P25788,P28074,Q96S59,Q99436,P30154,Q92796,Q92530,O00231,P06493,P28072 41
Abc family proteins mediated transport 0.4238654815935243 2.5126700639784936 0.0119821337577161 0.9999999417962734 0.0620198833451825 50 P49720,P62333,Q9UL46,O75832,P25789,P40855,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 21
P75ntr negatively regulates cell cycle via sc1 0.7598008711885498 2.509282971927378 0.0120976529492466 0.9999999504810068 0.0623841655815631 2 Q92769 1
Extra nuclear estrogen signaling 0.693237293004527 2.494864427798528 0.0126005262530206 0.999999975499444 0.0642580342497216 14 P04792,P12931,P28482,Q99873 4
Deubiquitination 0.3806472944128216 2.4816030546264876 0.0130792884070909 0.999999987466056 0.0656141390773653 93 Q16186,P49720,P62333,P61586,Q9UL46,O75832,Q96RU2,Q9NWV8,P25789,P14735,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,Q9NXR7,Q6GQQ9,O00233,P85037,Q96FW1,P20618,Q93009,Q9UPT9,Q13546,P48556,Q99460,Q86UV5,P25788,Q13309,P28074,Q99436,Q7Z434,Q9Y5K5,O00231,Q92530,P38398,P06493,P28072 39
Tp53 regulates transcription of caspase activators and caspases 0.8617368398423417 2.4316278494568326 0.0150311424687168 0.9999999991873676 0.0728878557605848 4 P55212,P42575 2
Signaling by leptin 0.7414436838830165 2.419641123760338 0.0155358311051445 0.9999999995997964 0.0748101692937623 2 Q06124 1
Pcp ce pathway 0.4007434117860495 2.394324674484716 0.0166510020059083 0.9999999999164372 0.0792855098745679 52 P49720,P62333,P61586,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,P20618,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 21
Tnfr1 induced proapoptotic signaling 0.7920635889716865 2.384747427783036 0.0170908507070253 0.9999999999549716 0.080134124611294 3 Q6GQQ9 1
Membrane trafficking 0.2991916502647783 2.3844358389367173 0.0171053305067523 0.999999999955879 0.080134124611294 234 Q9UKS6,O14976,P33908,Q9H0V9,Q9NVZ3,Q13561,Q9Y3P9,Q14203,P47755,P20336,Q15102,P84085,Q9UBW8,P60520,O75935,Q9UID3,Q9UJW0,P55735,O00471,Q92538,P50570,O00161,Q13409,Q9BXI6,Q96FJ2,Q9H0U4,P12931,Q9BUF5,Q9UJY4,Q9BVK6,Q9Y5X3,Q92905,Q96KP1,O60645,Q13492,O15155,Q9Y6I3,Q99816,Q9NVG8,Q4KMP7,O15027,P61923,P43034,Q92747,P47756,Q13190,O00743,Q04917,O15144,P04350,O15145,Q8WUX9,P53634,O00203,O43237,P61160,P52594,Q96JB2,Q9Y6G9,Q9BZE9,Q99747,Q15363,Q9Y496,P42566,O95487,O95295 66
Rhoh gtpase cycle 0.5648900537085877 2.3789200740089615 0.0173634403511266 0.9999999999693088 0.0810684951528955 23 P11182 1
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.7887076484653168 2.369316696142082 0.0178209864248231 0.9999999999838758 0.082602227496525 3 Q9NVD7 1
Cell cycle checkpoints 0.3077555788716164 2.3670424495013815 0.0179308760577967 0.999999999986186 0.082602227496525 140 P49720,P62333,P35249,Q9UL46,O75832,Q9NWV8,Q92674,P25789,P25787,P49721,Q16537,P55036,Q06323,P35998,P55735,Q9UNM6,Q9NXR7,O00233,Q96EA4,O14757,Q13409,Q96FJ2,P20618,P35250,P49736,Q9P258,P27694,O60566,P40937,O43913,Q9UBD5,O95067,Q99460,Q9UJX5,P40938,P25788,P43034,P24941,Q92547,Q2NKX8,Q04917,P28074,O43929,P35244,Q99436,O43237,Q15691,Q9Y6G9,O43684,P30154,O00231,Q92530,P38398,P14635,P06493,P28072 56
Beta catenin independent wnt signaling 0.3988841813643348 2.3604874488458623 0.0182509359012197 0.999999999991196 0.0837966558654009 59 P49720,P62333,P61586,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,P35222,Q9UNM6,O00233,P20618,P48556,Q99460,P25788,P28074,Q99436,O00231,Q92530,P28072 23
Fcgr activation 0.7787114845938479 2.3231991123317504 0.0201684584473191 0.9999999999994096 0.0896231819105952 3 P07947,P12931 2
Metabolic disorders of biological oxidation enzymes 0.8390032504336602 2.2992190260874046 0.0214925051552841 0.9999999999999089 0.0934045349830271 5 P48637,P48507 2
Inla mediated entry of listeria monocytogenes into host cells 0.7729947154855477 2.2967206595604814 0.0216347101255589 0.9999999999999256 0.0937278037414497 3 P35222 1
Nicotinamide salvaging 0.7156191661481006 2.291995148818485 0.0219059231136657 0.9999999999999492 0.0946062054471441 2 P43490 1
Signaling by vegf 0.4858633135358816 2.2721751104996084 0.0230759359419328 0.9999999999999902 0.0984288378757751 33 P04792,P35222,P14923,Q9Y6W5 4
Pd 1 signaling 0.7025513378967088 2.2267214733053993 0.0259658943853151 1.0 0.1090725411565518 2 Q06124 1
Displacement of dna glycosylase by apex1 0.8138140178558967 2.224259459505475 0.026130992618528 1.0 0.1094334296933507 4 P29372 1
Dna strand elongation 0.5052070719409526 2.2219428596630517 0.0262871674275402 1.0 0.1097548803167993 27 P27694,P35244,P39748,P35249,Q9Y2S7,P49005,Q9BRX5,P09884,Q14181,P40938,P18858,P35250,P49736,P12004,Q15054,P40937,P49643 17
Defective ripk1 mediated regulated necrosis 0.6981953951462488 2.2048626615034417 0.0274637333288394 1.0 0.112960950775167 2 Q13546 1
Resolution of abasic sites ap sites 0.490783419854786 2.201771488045041 0.0276814540560832 1.0 0.1135186038739081 30 P27694,P35244,P39748,P35249,Q9Y2S7,Q9UGN5,Q96T60,P56282,P40938,P27695,Q86W56,Q9NR33,P35250,P18858,P49005,Q15054,P40937,P29372 18
Phase 0 rapid depolarisation 0.6935283136278779 2.181386871120314 0.0291548138748023 1.0 0.1185535596460514 2 Q13555 1
Synthesis of pyrophosphates in the cytosol 0.7445987196742637 2.1640869718028375 0.0304576751960086 1.0 0.122361939304895 3 Q13572 1
Cdc6 association with the orc origin complex 0.7419856831621443 2.151789813495962 0.0314139125082266 1.0 0.1253228732424122 3 O43929,Q9UBD5 2
Synthesis of pc 0.7418434139568473 2.151119842822563 0.031466741689665 1.0 0.1253228732424122 3 P19784 1
Cyclin d associated events in g1 0.6535796925651423 2.14560919770398 0.0319041710115377 1.0 0.1262032788906362 13 P07948,P63151,Q00534,Q13616,P12931,P24941,Q13309,P63208,P11802 9
G alpha i signalling events 0.48765011505713 2.1428926999884204 0.0321217152908412 1.0 0.1262032788906362 29 P07602,P04083,Q86YR5,P28482,P12931,Q00535,P63096 7
Base excision repair 0.4697683647186088 2.1344435489359204 0.0328064899728175 1.0 0.1280750540746718 33 P39748,P35249,Q15054,Q9NR33,P35250,P18858,P27694,P40937,P29372,Q9Y2S7,P56282,P40938,Q86W56,Q15554,Q96T60,P27695,P35244,P49005,Q9UGN5 19
Glutathione synthesis and recycling 0.8077881619937866 2.1290381539466727 0.0332511038613665 1.0 0.129081532405642 6 P48506,Q8WUX2,P48507,P48637,O75223 5
Antigen processing cross presentation 0.3928909741582779 2.1121171420778286 0.0346764030358945 1.0 0.1329271958107828 49 P49720,P62333,Q9UL46,O75832,P25789,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,O00161,P20618,P48556,Q99460,Q12846,P25788,P28074,Q99436,O00231,Q92530,P28072 23
Ikk complex recruitment mediated by rip1 0.7924771409928656 2.0959543162066727 0.036086243680407 1.0 0.1348950708104515 5 Q6SZW1 1
Fbxw7 mutants and notch1 in cancer 0.7273576097105479 2.0826673800857054 0.0372815527615224 1.0 0.1377623152845562 3 P63208,P62877 2
Transcriptional regulation by runx1 0.3736796615876551 2.0800775589898337 0.0375184195661701 1.0 0.1380905340684663 69 P49720,Q99873,Q9UL46,O75832,P25789,P67870,Q06124,P25787,P49721,Q06323,P35998,O00233,Q00534,O15047,P12931,Q99460,Q9UBL3,P25788,P28074,Q15291,Q92530,P19784,P28072 23
Signaling by gpcr 0.3845075262520485 2.0795130710690657 0.0375702176626218 1.0 0.1380905340684663 50 Q86YR5,P04083,P61586,Q92974,Q14344,P60953,O75116,Q3ZCW2,P28482,P12931,P08134,P07602,Q13555,P62879,P63096,Q8NCG7,Q9NRV9,P30154,P62136,O43865,Q00535,P25098 22
Formation of xylulose 5 phosphate 0.7261126672891358 2.076762756141062 0.0378234612452428 1.0 0.1386525820714206 3 P14550,Q7Z4W1 2
Vegfr2 mediated vascular permeability 0.7237978794264011 2.07178922095035 0.0382851023617605 1.0 0.1396042518837811 9 P14923 1
Mapk3 erk1 activation 0.7226890756302511 2.0605075407041884 0.0393500457170981 1.0 0.1424826405874225 3 Q06124,Q02750 2
Synthesis of prostaglandins pg and thromboxanes tx 0.7223778400248881 2.059028524924335 0.0394915059871063 1.0 0.1424826405874225 3 Q15185,Q8N8N7 2
Aryl hydrocarbon receptor signalling 0.7220236728075506 2.0573452381745443 0.0396530287322502 1.0 0.1424826405874225 3 Q15185 1
Extension of telomeres 0.460750471136454 2.0566538289562417 0.0397195363857578 1.0 0.1424826405874225 33 P39748,P35249,Q9BUR4,Q15054,Q9NPE3,P09884,Q14181,P18858,P35250,P27694,P40937,P49643,Q9Y2S7,P40938,P24941,Q15554,O00743,P35244,Q8WVB6,P49005 20
Activation of irf3 irf7 mediated by tbk1 ikk epsilon 0.7217523767904721 2.056055637190057 0.0397771536750024 1.0 0.1424826405874225 3 Q6SZW1 1
Activation of atr in response to replication stress 0.5732096036911061 2.0558584256798915 0.0397961644477171 1.0 0.1424826405874225 18 O43929,P35244,P35249,O14757,P40938,P24941,O43913,P35250,P49736,P27694,Q9UBD5 11
Fructose metabolism 0.6670815183571879 2.0472857026150746 0.0406300408655737 1.0 0.1447183414335642 2 Q00796 1
Ptk6 regulates rtks and their effectors akt1 and dok1 0.6664592408214197 2.044108788449593 0.0409428011375758 1.0 0.1450844901849751 2 Q96P48 1
Negative regulation of flt3 0.6664592408214047 2.044108788449517 0.0409428011375834 1.0 0.1450844901849751 2 P41240 1
Telomere c strand lagging strand synthesis 0.5176295157441613 2.037144159072045 0.0416355977810227 1.0 0.1471369947942174 23 P27694,P35244,P39748,P35249,Q9Y2S7,P49005,P09884,Q14181,P40938,Q8WVB6,P18858,P35250,Q15554,P12004,Q15054,P40937,P49643 17
Intraflagellar transport 0.6729291711136933 2.0347651965609064 0.0418745045566928 1.0 0.1471369947942174 11 P68371,Q96FJ2,Q92973,Q9Y547,Q9BUF5,P04350,Q9Y496,Q9BW83 8
Interleukin 21 signaling 0.6642812694461743 2.032981907745136 0.0420543508999391 1.0 0.1471369947942174 2 P40763 1
Interleukin 9 signaling 0.6642812694461743 2.032981907745136 0.0420543508999391 1.0 0.1471369947942174 2 P40763 1
Clec7a dectin 1 induces nfat activation 0.663970130678283 2.0313913801012307 0.042215308148215 1.0 0.1473271612647303 2 O43865 1
Synthesis of substrates in n glycan biosythesis 0.5786378101849214 2.017184036296161 0.0436763113693841 1.0 0.1508121015832804 17 O14772,O95394,P34949,Q86YN1,Q9UJ70,O60547,P10619,Q9NR45,Q06210,Q96EK6 10
Activation of caspases through apoptosome mediated cleavage 0.7132048884697513 2.015343756528294 0.0438686431523001 1.0 0.1508121015832804 3 O14727 1
Smac xiap regulated apoptotic response 0.7132048884697513 2.015343756528294 0.0438686431523001 1.0 0.1508121015832804 3 O14727 1
Other interleukin signaling 0.7632048562354168 2.0003555365653805 0.0454618860179318 1.0 0.1532377981461115 4 Q15833,P40222 2
Aggrephagy 0.5864813241166253 1.9972877847442911 0.0457939295472822 1.0 0.1532377981461115 16 O43237,Q9Y6G9,Q13409,Q96FJ2,Q99497,Q9BUF5,P04350,P08670 8
Nade modulates death signalling 0.7089031350960148 1.9947951596092837 0.0460652255120259 1.0 0.1534027509822166 3 P42575 1
Cytochrome c mediated apoptotic response 0.7596262555216088 1.9843399426663095 0.0472179562521142 1.0 0.1553826298469749 4 O14727,P28482 2
Synthesis of ip2 ip and ins in the cytosol 0.7067100808754455 1.9843042918517868 0.0472219280287478 1.0 0.1553826298469749 3 P29218 1
Golgi to er retrograde transport 0.3657231498188192 1.977559843042513 0.0479783832264752 1.0 0.157072149231475 68 Q13561,Q14203,P47755,Q15102,P84085,O75935,Q9UJW0,Q92538,Q13409,Q96FJ2,Q9H0U4,Q9BUF5,Q9BVK6,P61923,P43034,P47756,Q8N6T3,P04350,O43237,Q9Y6G9,Q99747,Q15363,Q9Y496 23
Sumo is conjugated to e1 uba2 sae1 0.6530802738021223 1.975571159060826 0.048203367818417 1.0 0.157072149231475 2 Q9UBE0 1
Sumo is transferred from e1 to e2 ube2i ubc9 0.6530802738021223 1.975571159060826 0.048203367818417 1.0 0.157072149231475 2 Q9UBE0 1
Processing and activation of sumo 0.6530802738021223 1.975571159060826 0.048203367818417 1.0 0.157072149231475 2 Q9UBE0 1
Signaling by braf and raf1 fusions 0.4827159990691352 1.9698957021658112 0.0488503251106626 1.0 0.1581057360724492 26 O00203,Q02750,O95352,P51114,Q13555,P28482,P10398,P02545,P30086,P12931,O43252,Q9NRY5,P41240 13
Peptide ligand binding receptors 0.7686508746824324 1.9561750800077031 0.0504445330523337 1.0 0.1613757978664936 6 P07602,P04083 2
Class a 1 rhodopsin like receptors 0.7686508746824324 1.9561750800077031 0.0504445330523337 1.0 0.1613757978664936 6 P07602,P04083 2
Vesicle mediated transport 0.2781310728541402 1.9547541538191775 0.0506120948348887 1.0 0.1615379100734785 240 Q9UKS6,O14976,P33908,Q9H0V9,Q9NVZ3,Q13561,Q9Y3P9,Q14203,P47755,P20336,Q15102,P84085,Q9UBW8,P60520,O75935,Q9UID3,Q9UJW0,P55735,O00471,Q92538,P50570,O00161,Q13409,Q9BXI6,Q96FJ2,Q9H0U4,P12931,Q9BUF5,Q9UJY4,Q9BVK6,Q9Y5X3,Q92905,Q96KP1,O60645,Q13492,O15155,Q9Y6I3,Q99816,Q9NVG8,Q4KMP7,O15027,P61923,P43034,Q92747,P47756,Q13190,O00743,Q04917,O15144,P04350,O15145,Q8WUX9,P53634,O00203,O43237,P61160,P52594,Q96JB2,Q9Y6G9,Q9BZE9,Q99747,Q15363,Q9Y496,P42566,O95487,O95295 66
Lagging strand synthesis 0.5444431914161338 1.9428137382132613 0.0520386673840334 1.0 0.1634487234653049 19 P27694,P35244,P39748,P35249,Q9Y2S7,P09884,Q14181,P40938,P18858,P35250,P12004,P49005,Q15054,P40937,P49643 15
Methylation 0.6973819189037507 1.9411233986460836 0.0522433115575287 1.0 0.1637194026587407 9 P78417,Q99707,Q9Y5N5,Q9UI30,Q9HBK9 5
Nostrin mediated enos trafficking 0.6453018046048631 1.9355217642178 0.0529263005435394 1.0 0.1654159607859219 2 P50570 1
Autophagy 0.3818112591077026 1.9347248092725409 0.0530240742606102 1.0 0.1654159607859219 48 Q9NT62,P60520,O43237,Q99816,O95352,Q9Y4P1,Q8WUX9,Q9Y6G9,Q13409,Q96FJ2,P12931,Q99497,P67870,Q9BUF5,P04350,P19784,P08670,Q9NS69 18
Ub specific processing proteases 0.3581280956952261 1.9123631489388528 0.0558296312257922 1.0 0.1718408693854005 74 P49720,Q16186,P62333,Q9UL46,O75832,Q96RU2,P25789,P14735,P25787,P49721,P55036,Q06323,P35998,Q9UNM6,O00233,Q96FW1,P20618,Q93009,Q9UPT9,Q13546,P48556,Q99460,Q86UV5,P25788,Q13309,P28074,Q99436,O00231,Q92530,P28072 30
Synthesis of diphthamide eef2 0.7432910253213365 1.9109408234044991 0.0560121860846365 1.0 0.1720196470421504 4 P13639 1
Processive synthesis on the lagging strand 0.5923205456622568 1.9072531716590664 0.056487811034863 1.0 0.1723314676604429 14 P35244,P39748,Q9Y2S7,P09884,Q14181,P12004,P18858,P49005,P27694,Q15054,P49643 11
Polymerase switching on the c strand of the telomere 0.5605261435350932 1.9017036297081031 0.0572099110836867 1.0 0.1733861778895946 17 P35249,Q9Y2S7,P09884,P40938,Q14181,Q8WVB6,P12004,P35250,Q15554,P49005,Q15054,P40937,P49643 13
Ephb mediated forward signaling 0.5380715497917674 1.899963762166544 0.0574378753456563 1.0 0.1736961569533853 19 P60953,O75116,P61586,P61160,P07947,P07948,O15143,P61158,P12931,Q92747,O15144,O15145 12
Oncogenic mapk signaling 0.4466032971162131 1.898429744190172 0.0576394944811489 1.0 0.1738528457208974 32 P62140,O00203,Q02750,O95352,P51114,Q13555,P21359,Q99956,P28482,P10398,P02545,P30086,P12931,O43252,Q9NRY5,P41240 16
Adherens junctions interactions 0.7339020846957105 1.897656963894644 0.0577412852285759 1.0 0.1738528457208974 7 P14923 1
Myd88 independent tlr4 cascade 0.5359239430615323 1.8854921443509465 0.0593634240498093 1.0 0.1779615011645043 19 Q02750,P28482,Q13616,Q06124,P51452,Q6SZW1,Q13546,P63208 8
Mhc class ii antigen presentation 0.3574843793947768 1.881583539499057 0.0598925828848417 1.0 0.1791591981533579 55 P68371,Q13561,Q14203,P47755,Q14807,O75935,Q9UJW0,P55735,Q9NZ32,P50570,Q13409,Q96FJ2,Q13885,Q9BUF5,P10619,O94855,P52732,Q15436,P47756,P04350,P53634,O43237,Q9Y6G9,Q07866,Q9Y496,P07858,O95487 27
Regulation of plk1 activity at g2 m transition 0.4313538696547863 1.8743408567500632 0.0608834596012681 1.0 0.1812084421205638 35 P63208,P62140,O75935,O95067,P68371,Q13561,Q9H6D7,Q15691,Q14203,Q13409,O14974,Q13616,P43034,P07437,Q96CS2,P14635,P04350,Q9NVX0 18
Tp53 regulates transcription of cell death genes 0.7287218917306794 1.8736405071631936 0.060979990946905 1.0 0.1812084421205638 7 P55212,P42575 2
Asparagine n linked glycosylation 0.3030309254121617 1.872251547763263 0.0611718105859715 1.0 0.1812084421205638 117 Q13561,P33908,Q9H0V9,Q14203,P47755,Q06210,P84085,O75935,Q9UJW0,O95394,P55735,Q92538,O60547,Q13409,Q96FJ2,Q9H0U4,Q9BUF5,P10619,Q9BVK6,O15155,Q86YN1,O15027,P61923,Q9NR45,Q13190,P47756,O00743,P04350,P53634,O43237,Q96JB2,Q9UJ70,Q9Y6G9,Q99747,Q15363,O95487 36
Resolution of ap sites via the multiple nucleotide patch replacement pathway 0.4868438218208928 1.8695088963917763 0.0615520470806765 1.0 0.1812084421205638 24 P27694,P35244,P39748,P35249,Q9Y2S7,Q9UGN5,P56282,P40938,P27695,Q86W56,Q9NR33,P35250,P18858,P49005,Q15054,P40937 16
Signaling by wnt 0.341229034391696 1.869473809180057 0.0615569241593787 1.0 0.1812084421205638 90 P56545,P49720,P62333,P49841,Q13547,P61586,Q9UL46,O75832,P32121,P25789,P67870,P25787,P49721,Q16537,P55036,Q06323,P35998,P62877,P35222,Q9UNM6,O00233,P20618,Q13363,Q08209,P48556,Q99460,O75436,P62879,Q9UBL3,P25788,P63208,P28074,Q99436,Q96QK1,Q15291,Q13616,P30154,O00231,Q92530,P51665,P19784,P28072,P53680 43
Intracellular signaling by second messengers 0.3359932855697331 1.867370134913077 0.0618499173942765 1.0 0.1812084421205638 94 P49720,P62333,Q13547,Q9UL46,O75832,P25789,P67870,Q06124,P25787,P49721,Q16537,P55036,Q06323,P35998,Q9UNM6,Q92769,O00233,P28482,P12931,P20618,O75530,Q8TBX8,Q93009,Q99460,Q96B36,Q13555,P25788,P28074,Q99436,Q8WXI9,O43865,P30154,Q9UNE7,O00231,Q92530,P19784,P25098,P28072 38
Diseases of signal transduction by growth factor receptors and second messengers 0.2837344983971311 1.855661243045084 0.0635018583632853 1.0 0.1824523248608323 149 P62140,P49720,P62333,Q13547,P51114,Q9UL46,O75832,P49589,Q14203,P10398,Q16630,P25789,Q06124,Q9NRY5,P25787,P49721,Q16537,P55036,Q06323,P35998,P62877,P35222,Q9UNM6,P21359,Q92769,Q99956,P28482,O00233,P02545,P12931,P30086,P20618,O43252,P41240,P40763,Q99460,Q02750,O95352,Q96B36,P07947,P07948,Q13555,P25788,P62753,Q86WB0,P63208,P28074,Q99436,O00203,P62942,Q13616,P30154,Q16543,O00231,Q92530,P06753,P28072,P31939 58
Glutathione conjugation 0.5731337004480619 1.8509332631307456 0.0641791546825278 1.0 0.1840157505627666 15 O43708,P14550,Q96KP4,P48506,P78417,Q8WUX2,P48507,P48637,O75223,P21266 10
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.7296377919474731 1.849236031204295 0.0644237380596992 1.0 0.1843345879886218 4 P24941,Q00534 2
Parasite infection 0.4667681086231591 1.8438356363978443 0.0652070974835705 1.0 0.1861905138890382 26 P60953,P16333,P61160,P07947,P07948,P28482,P12931,Q9Y6W5,Q9UQB8,O15144,O15145 11
Regulation of bach1 activity 0.7275840597758397 1.8399272396790112 0.0657789202399041 1.0 0.1870503452089468 4 Q13309,P63208,P62877 3
Prolactin receptor signaling 0.7275840597758396 1.8399272396790085 0.0657789202399046 1.0 0.1870503452089468 4 Q06124,P63208,P62877 3
Cell cell junction organization 0.696158724251139 1.8232239116044573 0.0682694849120051 1.0 0.1911418747005435 8 P14923 1
Glucuronidation 0.6714038791760779 1.8140619411605192 0.0696681900965607 1.0 0.1939899598883515 3 O60701 1
Metabolism of amino acids and derivatives 0.2841674318969713 1.804996393729402 0.0710752463572488 1.0 0.1972409447102768 195 P11182,P62899,P49720,Q9UL46,P42766,P25789,P25325,Q96C36,P25787,O43175,P49721,Q06323,P35998,P62847,Q13155,P84098,O43708,P05388,Q13126,O00233,P62841,Q14353,Q9Y617,Q99707,P62753,O95340,Q7L266,P00966,P34896,P16930,P19623,P28072 32
Smooth muscle contraction 0.646078541163441 1.798672457006963 0.0720705082736423 1.0 0.1995994086818192 10 P04083,P07355 2
Signaling by robo receptors 0.2786157534050258 1.792274980446349 0.0730889290076008 1.0 0.2009132568433143 142 P16333,P62899,P49720,Q15369,P62333,P61586,Q9UL46,O75832,P60866,P42766,P62081,P08708,P46778,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,P60953,P62847,P84098,P05388,P62910,Q9UNM6,P62857,O00233,P62244,P12931,P26373,P62841,P23396,P20618,P15880,P46777,P48556,Q99460,P62906,P61513,P25788,P62854,P62753,P28074,Q99436,O75122,Q9Y5S9,O00231,Q92530,Q8N8S7,P25398,P28072 52
Mapk1 erk2 activation 0.6659829967108912 1.7877092887297006 0.0738229223427808 1.0 0.2016270329599272 3 P28482 1
E2f enabled inhibition of pre replication complex formation 0.7231392089691663 1.7856585186892722 0.0741545656371289 1.0 0.2021333524862174 5 O43929,Q9UBD5,P14635,O43913 4
Interleukin 20 family signaling 0.6644880174291963 1.7804323014148098 0.0750052393859634 1.0 0.2032627842472034 3 P40763,Q06124 2
Apoptotic cleavage of cell adhesion proteins 0.7087017060259585 1.7804023057765717 0.0750101446932516 1.0 0.2032627842472034 7 P15924,P35222,Q9UDY2 3
Cyclin a b1 b2 associated events during g2 m transition 0.606595548782087 1.7730323666329149 0.0762233437639472 1.0 0.2061461077921234 12 O95067,P63151,P30154,Q9Y570,P24941,P14635,P06493 7
Regulation of expression of slits and robos 0.2811117384265836 1.761554088473073 0.0781446667826322 1.0 0.2105183810791378 125 P62899,P49720,P62333,Q15369,Q9UL46,O75832,P60866,P42766,P62081,P08708,P46778,P25789,P25787,P49721,P55036,Q06323,P35998,P62877,P62847,P84098,P05388,P62910,Q9UNM6,P62857,O00233,P62244,P26373,P23396,P62841,P20618,P15880,P46777,P48556,Q99460,P62906,P61513,P25788,P62753,P28074,Q99436,Q9Y5S9,O00231,Q92530,P28072 44
Transport of connexons to the plasma membrane 0.7064134495641333 1.7435768069828104 0.0812329104539717 1.0 0.2170617244116434 4 Q9BUF5,P04350,P68371 3
Gap junction assembly 0.7064134495641333 1.7435768069828104 0.0812329104539717 1.0 0.2170617244116434 4 Q9BUF5,P04350,P68371 3
G2 m dna replication checkpoint 0.7062935357486798 1.743029104018071 0.0813285311402545 1.0 0.2170617244116434 4 O95067,P14635 2
Pecam1 interactions 0.7123010390453115 1.736444380201897 0.0824852908419542 1.0 0.21964291318609 5 P07947,P12931,Q06124 3
Polymerase switching 0.5623706748587158 1.7272367374444084 0.0841251555164752 1.0 0.2235787786995554 14 P35249,Q9Y2S7,P09884,P40938,Q14181,P12004,P35250,P49005,Q15054,P40937,P49643 11
E2f mediated regulation of dna replication 0.597238066301355 1.7205055015023731 0.0853405945122742 1.0 0.2246099617333009 12 O43929,P49643,P09884,Q14181,P30154,O43913,P14635,P06493,Q9UBD5 9
Erbb2 regulates cell motility 0.6008089607965201 1.7037917150994428 0.0884200063338622 1.0 0.2292616299313276 2 P61586 1
Regulation of runx1 expression and activity 0.7012524660762615 1.6861031905067323 0.0917759255944368 1.0 0.2331513403888082 5 P12931,Q06124,Q00534 3
Leishmania infection 0.3840485033040228 1.6825955834726771 0.0924534072580698 1.0 0.2344414840929403 42 P16333,Q9Y6W5,Q9UQB8,Q9Y3E5,P60953,O15143,P28482,P12931,P07947,P07948,P62879,P61158,Q9Y2Z0,Q8WUW1,Q92747,P63096,O15144,O15145,P61160,P13861,P09601,O00401,O43865 23
Nucleotide salvage 0.6660524165239284 1.6770373951448143 0.0935351695773816 1.0 0.2363173754221963 8 P04183,Q9BZX2,Q9P2T1,Q01433,P00491 5
Erythropoietin activates phospholipase c gamma plcg 0.5924082140634801 1.659581215878372 0.0969987297694816 1.0 0.2428669078759471 2 P07948 1
Activation of smo 0.639589169000918 1.6586719713433995 0.0971819103150497 1.0 0.2428669078759471 3 Q9Y496,P25098 2
Pcna dependent long patch base excision repair 0.4903948733689321 1.6483653576568458 0.099277720350539 1.0 0.2458011300622101 20 P27694,P35244,P39748,P35249,Q9Y2S7,P56282,P40938,P27695,Q9NR33,P35250,P18858,P49005,Q15054,P40937 14
Intra golgi traffic 0.6384475701527011 1.644763291887106 0.1000186349138259 1.0 0.246831702590906 9 P33908,Q96JB2,Q13190 3
Metalloprotease dubs 0.6989264568626934 1.6419794913687644 0.1005942543821363 1.0 0.2478097318290773 6 Q9NXR7,Q9NWV8 2
Smad2 smad3 smad4 heterotrimer regulates transcription 0.6816146947995778 1.6298822512882316 0.1031263855188759 1.0 0.2518032946768315 4 P28482,Q13547 2
O linked glycosylation 0.6327419856831611 1.6250160400792275 0.1041591411104578 1.0 0.2534294595328394 3 O43505,Q86SF2 2
O linked glycosylation of mucins 0.6327419856831611 1.6250160400792275 0.1041591411104578 1.0 0.2534294595328394 3 O43505,Q86SF2 2
Rho gtpases activate iqgaps 0.608605908578103 1.6012990272685956 0.1093107043761101 1.0 0.2641038346989234 10 P60953,P35222,P68371,Q9BUF5,P04350,Q86VI3 6
Ctla4 inhibitory signaling 0.6502502338421351 1.5997850176560149 0.1096462836441189 1.0 0.2644522931870374 8 P07947,P07948,P12931,P30154,Q06124 5
Regulation of mrna stability by proteins that bind au rich elements 0.3353477589297496 1.5967067041028815 0.1103311005579761 1.0 0.2656403849671132 65 P28074,P49720,Q9NQT5,Q99460,Q96B26,Q92530,Q9UL46,O75832,P04792,O00233,P25788,P25789,P25787,P49721,Q06323,P35998,P28072 17
Hs gag degradation 0.5780958307405164 1.5839765950505662 0.1131990453436175 1.0 0.2715567851266846 2 P54802 1
Diseases of immune system 0.5777846919726247 1.5823293638060076 0.1135744007259216 1.0 0.2715567851266846 2 O15111 1
Nervous system development 0.2684887440458096 1.574557539469658 0.1153586102350532 1.0 0.2752039288854705 221 P16333,Q13322,P42766,P62081,P67870,Q06124,P25787,P62847,P62910,Q7Z406,P62857,P50570,P62841,P08134,Q99460,P62753,O15144,P28074,P61160,Q92796,Q92530,Q8N8S7,P62899,Q9UL46,O75832,P08708,P55036,Q06323,P62877,P60953,Q92769,P12931,Q14195,P07947,P07948,Q92747,P04350,Q16555,Q00535,P19784,P49720,Q15369,P68371,P60866,P25789,P49721,P84098,P28482,P26373,P23396,Q9BUF5,P20618,P15880,Q02750,O15145,Q96S59,Q99436,O00231,P28072,P62333,P61586,P46778,P35998,O75116,P05388,Q9UNM6,P18433,O00233,P62244,Q13885,P46777,P48556,P62906,P61513,P61158,P25788,Q9Y5S9 77
Map3k8 tpl2 dependent mapk1 3 activation 0.6693648816936477 1.5734341768665512 0.1156183185238031 1.0 0.2752039288854705 4 Q02750,P63208,Q13616 3
Global genome nucleotide excision repair gg ner 0.3614422401801077 1.573048373431791 0.1157076177305629 1.0 0.2752039288854705 45 P35249,Q15054,P18074,Q9UBW8,P62877,P18858,P35250,Q9NR33,Q92905,P27694,P40937,Q9Y2S7,P56282,P40938,Q9BT78,P35244,Q9UNS2,P49005,Q9UGN5 19
Phosphorylation of emi1 0.6209150326797392 1.566730207411526 0.1171777668987918 1.0 0.2777695949470504 3 P14635,P06493 2
Triglyceride metabolism 0.6618238861214455 1.559814202386259 0.1188037942399355 1.0 0.2797050147182129 7 P62140,P62136,Q01469 3
Triglyceride catabolism 0.6618238861214455 1.559814202386259 0.1188037942399355 1.0 0.2797050147182129 7 P62140,P62136,Q01469 3
Degradation of the extracellular matrix 0.621310838750061 1.5575796318638404 0.1193329301055223 1.0 0.280020437674904 9 P42574,P17655,P04632 3
Dual incision in gg ner 0.423050532317626 1.5575371455279392 0.1193430085314894 1.0 0.280020437674904 27 P27694,P35244,P35249,Q9Y2S7,Q9UGN5,P56282,P40938,Q9NR33,P35250,P49005,Q15054,P40937,P18074,P62877 14
Interleukin 6 family signaling 0.6646948941469479 1.5518713153304573 0.1206930176583314 1.0 0.2816837674453898 4 P40763,P22681,Q06124 3
Interleukin 6 signaling 0.6646948941469479 1.5518713153304573 0.1206930176583314 1.0 0.2816837674453898 4 P40763,P22681,Q06124 3
Activation of ampk downstream of nmdars 0.6599925588612874 1.5511439002303138 0.1208672026737454 1.0 0.2816837674453898 7 P54646,Q9BUF5,P04350,P68371 4
Mastl facilitates mitotic progression 0.6703249929070797 1.544383112916056 0.1224955485813441 1.0 0.283565909781269 5 Q96GX5,P14635,P30154 3
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.6604228401511726 1.5321268214127235 0.1254911422258113 1.0 0.2898915113536002 4 Q13546 1
Recycling of eif2 gdp 0.6363300359585696 1.5314928862680308 0.1256476232277905 1.0 0.2898915113536002 8 Q9UI10,Q9NR50 2
Tgf beta receptor signaling activates smads 0.5782346574026214 1.522586604101823 0.1278621633155521 1.0 0.2924496811778022 11 P62140,P61081,P62942,Q9UNE7,Q9Y5K5,P62136 6
Copii mediated vesicle transport 0.4032641536178765 1.5218985489582832 0.1280345028257352 1.0 0.2924496811778022 32 P53634,O15155,P55735,O15027,Q9H0V9,Q99747,Q15363,Q13190,O00743,O95487 10
Activation of the pre replicative complex 0.4618705832591904 1.5211439556272048 0.1282237159814858 1.0 0.2924496811778022 21 O43929,P35244,Q9UBD5,P56282,P09884,Q14181,P24941,O43913,Q9NR33,P49736,P49643 11
Protein ubiquitination 0.4263846237751056 1.521088205337009 0.1282377039028568 1.0 0.2924496811778022 26 P60604,Q5VTR2 2
Carboxyterminal post translational modifications of tubulin 0.6715894839464035 1.517071801959741 0.1292485566890933 1.0 0.2942693663003738 6 Q14166,Q9BUF5,P04350,P68371 4
Cell junction organization 0.5003392571041255 1.5119682577409277 0.1305419378369168 1.0 0.2962380264213777 17 P35222,P14923 2
Regulation of tnfr1 signaling 0.6697819314641751 1.508788361029913 0.1313528760481739 1.0 0.2966118189204154 6 Q6GQQ9,Q96BN8,Q12933,P63244,Q13546 5
Mismatch repair 0.543203641562751 1.5079584733170914 0.1315651555703434 1.0 0.2966118189204154 13 P43246,P35244,Q9Y2S7,P18858,P49005,P27694,Q15054 7
Enos activation 0.6549824422056458 1.5069580723713776 0.1318214045689507 1.0 0.2967055067007979 4 O75608 1
Synthesis of udp n acetyl glucosamine 0.6601055940206066 1.4973393332920018 0.1343049851745519 1.0 0.3013141063494006 5 Q9UJ70,Q06210,O95394 3
Separation of sister chromatids 0.296755501670602 1.492989531392583 0.1354399272164494 1.0 0.302357518377351 106 P49720,P62333,P68371,Q9UL46,O75832,Q92674,P25789,P25787,P49721,Q16537,P55036,Q06323,P35998,P55735,Q9UNM6,O00233,Q96EA4,Q13409,Q14674,Q96FJ2,Q13885,Q9BUF5,P20618,Q9P258,O60566,Q9UJX5,Q99460,P25788,P43034,Q7Z5K2,Q2NKX8,P04350,P28074,Q99436,O43237,Q15691,Q9Y6G9,O43684,P30154,O00231,Q92530,P28072 42
Maturation of sars cov 2 nucleoprotein 0.6517961892118294 1.4922058227408683 0.1356451963776828 1.0 0.302357518377351 4 Q99873 1
Recognition of dna damage by pcna containing replication complex 0.4290755565470182 1.4829479897756666 0.1380882297508923 1.0 0.3067194537967902 25 P27694,Q9NZJ0,P35244,P35249,Q9Y2S7,P56282,P40938,P62877,Q9NR33,P35250,P49005,Q15054,P40937,O94782 14
Polb dependent long patch base excision repair 0.6455238991469497 1.4825393599390209 0.1381968387158552 1.0 0.3067194537967902 7 Q9UGN5,P27695,Q86W56,P18858 4
Hsf1 dependent transactivation 0.5047508172904819 1.481591099065539 0.1384491288288369 1.0 0.3067194537967902 16 P04792,P54652,Q96B36 3
Regulation of tp53 activity through methylation 0.601711713546907 1.471741422852322 0.141090717166334 1.0 0.3095037636886883 3 Q8N0Z6 1
Anchoring of the basal body to the plasma membrane 0.4037841274348236 1.470369426819858 0.14146172702062 1.0 0.3098258426980932 30 O75935,Q13561,Q9H6D7,Q15691,Q14203,Q13409,P43034,P07437,Q96CS2,Q8IW35,P04350,Q9NVX0 12
Processive synthesis on the c strand of the telomere 0.5356639286927045 1.4636037346535935 0.14330225155267 1.0 0.3123717849302682 13 P35244,P39748,Q9Y2S7,Q15554,P18858,P49005,P27694,Q15054 8
Interleukin 17 signaling 0.518675361719837 1.461503379458104 0.1438773488005349 1.0 0.3131314898304556 14 Q02750,O15111,P28482,Q13616,P30154,P51452,P63208 7
G1 s specific transcription 0.6217352212441575 1.4597026348241342 0.1443718174606456 1.0 0.313299509521295 8 Q13547,P04183,P09884,P04818,P31350,P06493 6
Pentose phosphate pathway 0.5791482456550435 1.4448463831007574 0.1485010393722645 1.0 0.3207962278133097 10 P11908,P60891,O95336,Q9Y315,P11413 5
Hsf1 activation 0.5159143594713874 1.444637413047826 0.1485597581769306 1.0 0.3207962278133097 14 P04792 1
Purine ribonucleoside monophosphate biosynthesis 0.5767311291328753 1.431977959785466 0.1521501290805349 1.0 0.3270162960953333 10 P22234,P49915,P12268,P22102,O15067,P20839,Q06203,P30520,P31939 9
Downregulation of tgf beta receptor signaling 0.6342304066316924 1.4288861731298572 0.1530369521787877 1.0 0.3284115961352247 7 Q9UNE7,Q9Y5K5,P62136 3
Tnf signaling 0.6327669543058289 1.4219285521959717 0.1550469934399112 1.0 0.3313131468033014 7 Q6GQQ9,Q96BN8,Q12933,P63244,Q13546 5
Gap filling dna repair synthesis and ligation in gg ner 0.4581858086619538 1.4217175843663754 0.1551082532429348 1.0 0.3313131468033014 20 P27694,P35244,P35249,Q9Y2S7,P35250,P56282,P40938,P18858,Q9NR33,P49005,Q15054,P40937 12
Arachidonic acid metabolism 0.6354195928668676 1.4162679647290248 0.1566970634987494 1.0 0.3341903422149255 4 Q15185,Q8N8N7 2
Signal attenuation 0.5888719417349743 1.4080453198485463 0.1591176507483944 1.0 0.3388298818710032 3 P28482 1
Rho gtpases activate wasps and waves 0.4560558224574166 1.406701819697591 0.1595158259363098 1.0 0.3391551868368926 20 P60953,P16333,P61160,O15143,Q92747,P28482,P61158,Q8WUW1,Q9Y6W5,Q9UQB8,O15144,O15145 12
Gpvi mediated activation cascade 0.6448328553832932 1.3942394144067802 0.1632453194207439 1.0 0.3454900940880063 6 P60953,P07948,Q06124 3
Striated muscle contraction 0.6286872943382293 1.3850073287294988 0.166050226429804 1.0 0.3508890105901975 4 P06753 1
Raf independent mapk1 3 activation 0.6424243034599358 1.383165557518001 0.1666141079384031 1.0 0.3515430491158369 6 P28482,Q99956,Q06124,Q02750 4
Ovarian tumor domain proteases 0.5861960363037634 1.378090957895758 0.1681752069319557 1.0 0.3542959389938458 9 Q6GQQ9,Q13546,Q96FW1 3
Sema4d induced cell migration and growth cone collapse 0.5858455831911265 1.3762964772854676 0.1687298631002782 1.0 0.3549233954407679 9 Q7Z406,P08134 2
Translocation of slc2a4 glut4 to the plasma membrane 0.3783517453200599 1.3621546666663011 0.1731490791010146 1.0 0.3598376350640634 34 O60645,O00471,Q9BZE9,Q04917,Q9Y496,Q96KP1,P04350 7
Phase i functionalization of compounds 0.4851259824652132 1.356270542018539 0.1750131046164638 1.0 0.3626208554422083 16 Q969Z3,O00170,O43169,Q15185,P07099,Q96DG6 6
Synthesis of pips at the early endosome membrane 0.6220036101247308 1.3539565307270771 0.1757502464148268 1.0 0.3633464720731035 4 Q13614 1
Attenuation phase 0.5474707563100966 1.3535141512992328 0.1758914322376752 1.0 0.3633464720731035 11 P04792,P54652 2
Runx2 regulates osteoblast differentiation 0.6271326163033053 1.3450997286875128 0.1785930308332486 1.0 0.3662500925629066 5 P07947,P12931,P28482 3
Nucleotide biosynthesis 0.5155236817582642 1.3449849500144877 0.1786300947866943 1.0 0.3662500925629066 13 P11172,P22234,P49915,P12268,P22102,O15067,P20839,Q06203,P30520,P31939 10
Selective autophagy 0.3859963795710036 1.3441966222033126 0.1788848136613328 1.0 0.3662500925629066 31 O43237,Q9Y6G9,Q13409,Q96FJ2,P12931,Q99497,P67870,Q9BUF5,P04350,P19784,P08670,Q9NS69 12
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.545405288591285 1.342152340721653 0.1795466058528587 1.0 0.367061256344158 11 P42575 1
Toll like receptor cascades 0.4097170961043405 1.3308595303329052 0.1832352355811792 1.0 0.3729471216099996 25 Q02750,P50570,P28482,Q13616,Q06124,P51452,Q6SZW1,P07858,Q13546,P63208 10
Dcc mediated attractive signaling 0.6302441039025843 1.327146299343337 0.1844602922436888 1.0 0.3743379205297768 6 P16333,P12931 2
Tnfr1 induced nfkappab signaling pathway 0.629419923895643 1.3233552496851608 0.1857172662220192 1.0 0.3763361611713058 6 Q6GQQ9,P63244,Q12933,Q13546 4
Activation of nima kinases nek9 nek6 nek7 0.6213017751479237 1.318142049214417 0.1874561005351589 1.0 0.3781961035614447 5 Q8TD19,O95067,P14635,P06493 4
Diseases associated with glycosylation precursor biosynthesis 0.5916602636578022 1.3114398967851852 0.1897091871224512 1.0 0.3816275059726747 8 P36871,P10619,Q06210,P51570 4
Akt phosphorylates targets in the cytosol 0.6120428487789884 1.3076662564246946 0.1909865332525719 1.0 0.3836386467369977 4 O15111,Q96B36 2
Ngf stimulated transcription 0.5676009263999665 1.30234721676178 0.192797717582851 1.0 0.3867147252532658 3 Q00535 1
Cargo trafficking to the periciliary membrane 0.4589561832876456 1.2983724128365155 0.1941593941331971 1.0 0.3888815691189543 18 O60645,P48643,O00471,Q9H0F7,Q96KP1 5
Recruitment of mitotic centrosome proteins and complexes 0.3832581389925178 1.295750980749659 0.1950612911717084 1.0 0.3901225823434169 30 O75935,P68371,Q13561,Q9H6D7,Q15691,Q14203,Q96CW5,Q13409,P43034,P21127,P07437,Q96CS2,P04350,Q9NVX0 14
Fcgamma receptor fcgr dependent phagocytosis 0.3705006075708656 1.291964029909718 0.1963696016527019 1.0 0.3921716611040954 34 P60953,P16333,P61160,P07947,P07948,Q8IV08,P28482,P12931,Q9Y6W5,Q9UQB8,O15144,O15145 12
Formation of tubulin folding intermediates by cct tric 0.520167034150007 1.283611027755113 0.1992780892365462 1.0 0.3964466479222409 12 Q9BUF5,P48643,P04350,P68371 4
Peptide hormone metabolism 0.5201204526964912 1.2833462906633204 0.199370781697509 1.0 0.3964466479222409 12 O60645,O00471,Q96KP1,P35222 4
Cell cell communication 0.3804500249466752 1.2719306198757807 0.203397771347523 1.0 0.4032937159286611 30 Q15149,P35222,P14923 3
Phenylalanine and tyrosine metabolism 0.6106409829981271 1.2688587794146102 0.2044914363274248 1.0 0.4043480813321264 5 Q7L266,O43708 2
Signaling by interleukins 0.2796754540520815 1.26683739361974 0.2052134383626591 1.0 0.4045719997392225 108 P42574,P49720,P04083,Q9UL46,O75832,P25789,Q06124,P25787,P49721,P55036,Q06323,P35998,P62877,P60953,Q15833,P05388,Q13126,O00233,Q07820,P28482,P78417,P20618,P46109,P40763,Q53EL6,Q99460,P14174,Q02750,P07947,P07948,O00170,P25788,P52597,P51452,P63208,Q9H3K6,P28074,Q99436,Q99439,Q13616,P30154,P07355,Q92530,O00231,P08670,P28072,P40222 47
Cell cycle mitotic 0.2423874414671455 1.2612203689073662 0.207229461929352 1.0 0.4063037781943576 254 P67870,P25787,Q96EA4,O14974,P02545,P07437,P18858,P49736,P04818,Q99460,Q9Y2S7,Q7Z5K2,P28074,P35244,O43237,Q15691,P04183,Q92530,Q9UL46,O75832,P55036,Q06323,P62877,Q96CW5,Q13409,Q9H0U4,P12931,Q9NR33,P07948,P40938,P43034,Q2NKX8,P04350,O43929,Q9H6D7,Q96CS2,O43684,P49005,P19784,P14635,P62140,P49720,P39748,Q13547,P68371,Q13561,Q96GX5,Q9BRX5,Q14203,Q92973,P25789,P49721,Q9NVX0,P55735,P28482,P09884,Q96FJ2,Q9BUF5,P21127,P20618,P35250,Q9P258,O60566,P49643,O43913,O95067,P56282,Q99436,Q13616,P30154,O00231,P06493,P28072,P62333,P35249,Q92674,Q16537,Q15054,P35998,O75935,Q9UNM6,Q9UIC8,O00233,Q00534,Q14674,Q14181,Q99986,Q13885,P27694,P31350,P40937,Q9UBD5,Q9UJX5,P63151,P25788,P24941,Q13309,P63208,Q8WUX9,Q9Y6G9,Q9Y570,P11802 102
Rho gtpases activate rocks 0.5154210680190214 1.256646537976596 0.2088816550492309 1.0 0.4087171119790002 12 P62140,O75116,Q7Z406,O14974,P08134 5
Pi5p regulates tp53 acetylation 0.6003115804412378 1.2531544612434815 0.2101494991748693 1.0 0.4102070732481206 4 Q13526 1
Erks are inactivated 0.6063380481800489 1.2489744219208732 0.2116744293071764 1.0 0.4123767434344753 5 P51452,P28482 2
Rho gtpases activate cit 0.5283655309165709 1.2484732299514314 0.2118578059612716 1.0 0.4123767434344753 11 Q7Z406 1
Tbc rabgaps 0.4597041637119129 1.2464993392889565 0.2125811316231693 1.0 0.4127231286800947 17 P61020,P60520,Q9NVG8,Q4KMP7,P62330,Q9Y3P9,Q9BXI6,Q9UJY4 8
Telomere c strand synthesis initiation 0.6122102761347739 1.2442187059937215 0.2134190809785603 1.0 0.4127231286800947 6 Q14181,P49643,Q15554,P09884 4
Signaling by wnt in cancer 0.5770556516945535 1.239452417584133 0.2151779997222682 1.0 0.4147503425609131 8 P56545,P35222,P30154,Q13363,Q16537 5
Robo receptors bind akap5 0.5127566894835193 1.2359946796680406 0.2164605412973201 1.0 0.4166413204357889 2 P13861 1
Purine salvage 0.6097134647342339 1.2327456592312265 0.2176706710251266 1.0 0.4183878544599791 6 P00491,Q01433,Q9P2T1 3
Negative feedback regulation of mapk pathway 0.5527600235439505 1.2285939457312127 0.2192240865578441 1.0 0.4205206984136352 3 P28482 1
Vxpx cargo targeting to cilium 0.5740348403414485 1.2245764524874343 0.2207348445376125 1.0 0.4219302284245926 8 O60645,Q96KP1 2
Activation of ppargc1a pgc 1alpha by phosphorylation 0.5511982570806137 1.2208374438509693 0.222147573546352 1.0 0.4234592367462876 3 P54646,Q16539 2
Pp2a mediated dephosphorylation of key metabolic factors 0.5508870214752613 1.219291862603458 0.2227334360622368 1.0 0.4239911964710899 3 P30154,P30153 2
Rhoq gtpase cycle 0.412593088607694 1.206727177651564 0.2275372289813617 1.0 0.4289992502759098 22 P14923 1
Metabolism of nucleotides 0.3142486964260224 1.1972090739967212 0.2312250739620367 1.0 0.4341753426841505 48 P49915,P20839,Q9NRF8,O43598,Q9Y3D8,P00492,P04818,P49902,P15531,P12268,P30520,Q9BZX2,Q9P2T1,Q13232,Q8TCD5,Q01433,P00491,P04183,Q16881,Q96DE0,P30085,P31939 22
Post translational protein modification 0.2156039404031492 1.1888265521201853 0.2345079272353523 1.0 0.4388190100547282 403 P52739,Q5VTR2,P33908,Q9NWV8,P25787,Q9NZJ0,Q9UJW0,P10619,P60604,Q8NEZ5,Q99460,O15027,P61923,Q9NR45,P47756,O00743,O43505,P28074,O43237,Q9UJ70,Q9BZG1,Q99497,Q96MG7,O75150,Q92530,Q9BTE7,Q9BW61,Q9UBE0,Q9ULX3,Q9UL46,O75832,Q9H0V9,Q96RU2,P47755,P20336,P14735,P55036,Q06323,Q06210,P84085,P62877,Q96GG9,Q14999,Q9NXR7,Q6GQQ9,Q92538,Q92769,P85037,Q13409,Q9H0U4,Q9ULC3,Q9UPT9,Q13564,Q13546,O15155,Q9P000,P04350,Q96JB2,Q15291,Q15363,P49720,Q13561,Q9H0A8,Q14203,P25789,P49721,Q9Y3I1,Q9UBW8,P55735,O60547,Q96FJ2,Q96FW1,Q9BUF5,Q93009,P13639,P53634,Q8TBC4,Q7Z434,Q9Y5K5,P28072,Q9BU89,Q9H2P9,P35998,O75935,O95394,O00233,Q9BVK6,Q92905,Q9UBI1,Q9NXF7,Q86YN1,P25788,Q13190,Q13309,Q14166,P63208,Q9Y6G9,Q99747,P38398,O95487 100
G alpha q signalling events 0.4889108595453423 1.188463920222957 0.234650686273838 1.0 0.4388190100547282 13 Q3ZCW2,P28482,P04083 3
Budding and maturation of hiv virion 0.5815108963580925 1.1782015651381752 0.2387162587665197 1.0 0.4452170979963971 7 Q99816 1
Inositol phosphate metabolism 0.5449114899795227 1.1669257476909078 0.2432403569141874 1.0 0.4524336113800902 9 P29218,Q92551,Q9NPH2,Q13572 4
Formation of incision complex in gg ner 0.4538063534550882 1.1567577212521292 0.2473713596912088 1.0 0.4583654661948111 16 P35244,Q9UGN5 2
Epha mediated growth cone collapse 0.509448454031244 1.1447875836354324 0.2522971599514414 1.0 0.4661426137070749 11 O75116,Q7Z406,P07948,P07947,P12931 5
Caspase mediated cleavage of cytoskeletal proteins 0.5567761457281252 1.139751776804031 0.2543897294084061 1.0 0.467965348429619 8 Q15149,P42574,P55212 3
Negative regulation of mapk pathway 0.4658469618180663 1.1392009581266254 0.2546193460473294 1.0 0.467965348429619 14 Q02750,Q99956,P28482,P10398,P30086,P30154 6
G alpha 12 13 signalling events 0.5216900994909627 1.1391558328647189 0.2546381635449157 1.0 0.467965348429619 10 O75116,P61586,P62879,Q92974,O15085,Q14344,P08134 7
Receptor mediated mitophagy 0.5752035465066843 1.1367108438167195 0.2556591846634393 1.0 0.4685954817040758 4 P12931,P19784 2
E3 ubiquitin ligases ubiquitinate target proteins 0.4343036283673429 1.1340358652908782 0.2567795039915101 1.0 0.4697782098550176 18 Q5VTR2 1
Golgi cisternae pericentriolar stack reorganization 0.507391527394553 1.1335477104590852 0.2569843174026001 1.0 0.4697782098550176 11 O95067,P28482,Q9H8Y8,Q9H0U4,P14635,P06493 6
G alpha s signalling events 0.5378448052081936 1.1309319390498542 0.2580837390487924 1.0 0.4709496096322908 9 P62879,P12931,P63096,P25098,Q9Y3E5 5
Mtor signalling 0.4568020137507835 1.128161903075127 0.259251549889097 1.0 0.4719376004663249 15 P62942,P62753 2
Mtorc1 mediated signalling 0.5062839639286367 1.1274990750167306 0.259531531370772 1.0 0.4719376004663249 11 P62942,P62753 2
Inactivation of csf3 g csf signaling 0.5860661863108146 1.1243191037703577 0.2608776768070027 1.0 0.4722748851699012 6 P40763,P07948,P42224,Q15369 4
Small interfering rna sirna biogenesis 0.5720739033783991 1.1222367901909094 0.2617617738855076 1.0 0.4722748851699012 4 Q15633,Q15631 2
Amino acids regulate mtorc1 0.4773576256011098 1.120837359626585 0.262357098398164 1.0 0.4722748851699012 13 Q8NFG4,P38606 2
Traf6 mediated nf kb activation 0.5783245094985918 1.1198149907841095 0.2627926097653068 1.0 0.4722748851699012 5 O15111,Q12933,Q7Z434,Q14258 4
Signal amplification 0.5349112639751186 1.1160140768310516 0.2644161090906607 1.0 0.4745754061860949 9 P62879,Q14344,P12931,Q13685,P63096 5
Termination of translesion dna synthesis 0.4230235413827322 1.1143723342393326 0.2651194869511246 1.0 0.4749431185221864 19 P35244,P35249,Q9Y2S7,P56282,P40938,Q9NR33,P35250,P49005,P27694,P40937,Q15054 11
Costimulation by the cd28 family 0.4545020039431985 1.1139321113941054 0.2653083122280231 1.0 0.4749431185221864 15 P60953,P07947,P07948,P12931,P30154,Q06124,Q16537 7
Gpcr ligand binding 0.5165945261253391 1.1122008728394843 0.2660517927204893 1.0 0.4756579269595293 10 P07602,P04083 2
Oncogene induced senescence 0.5653025180992806 1.1014812242112046 0.2706872717753401 1.0 0.4828233969374437 7 P28482,Q00534 2
Death receptor signalling 0.3981808165846884 1.1013176840950665 0.270758417240607 1.0 0.4828233969374437 22 P42574,Q13547,P61586,Q96BN8,O15111,Q6GQQ9,Q92769,Q12933,Q92974,P63244,P42575,Q14344,Q13546 13
Generation of second messenger molecules 0.5741112864842612 1.100460680989937 0.2711314520356414 1.0 0.482865549888217 5 Q8N8S7 1
Recruitment of numa to mitotic centrosomes 0.3546482247234375 1.0996175612325834 0.2714987871789684 1.0 0.4828974567327341 32 O75935,Q13561,Q9H6D7,Q15691,Q14203,Q96CW5,Q13409,P43034,P07437,Q9BUF5,Q96CS2,P04350,Q9NVX0 13
Homology directed repair 0.3252419685762921 1.098180330361825 0.2721257534553341 1.0 0.4831638186786423 42 P27694,P35244,P39748,P35249,Q9Y2S7,Q9UGN5,P49005,Q9NXR7,P56282,O14757,Q9NWV8,P40938,P24941,Q9NR33,P35250,Q92547,P38398,Q15054 18
Cytoprotection by hmox1 0.2945145746185061 1.0976719382076836 0.2723477675475125 1.0 0.4831638186786423 68 P49720,P62333,Q9UL46,O75832,P25789,P67870,Q86X55,P25787,P49721,P55036,Q06323,P35998,P62877,Q9UNM6,O00233,P20618,P40763,Q99460,P25788,Q13309,P63208,P28074,Q99436,Q13616,O43819,O00231,Q92530,P19784,P28072 29
Activation of nmda receptors and postsynaptic events 0.3793597392186235 1.0940144452573006 0.2739486428366144 1.0 0.4853808005130784 25 P68371,P54646,Q13555,Q9NUP9,P28482,P49593,P12931,Q13885,Q9BUF5,Q92796,P04350 11
Cobalamin cbl vitamin b12 transport and metabolism 0.5648033021246588 1.0886619384412977 0.2763029920947821 1.0 0.4883001727301648 4 Q99707 1
Defects in cobalamin b12 metabolism 0.5648033021246588 1.0886619384412977 0.2763029920947821 1.0 0.4883001727301648 4 Q99707 1
Signaling by egfr 0.4854087395164357 1.0868627657669432 0.2770974638362142 1.0 0.4883178394572317 12 P60953,Q9Y6I3,Q99961,P12931,Q06124,Q13685,P42566,P41240 8
Sialic acid metabolism 0.5709559430728524 1.085983083218552 0.2774864766835576 1.0 0.4883178394572317 5 P10619 1
Metabolism of nitric oxide nos3 activation and regulation 0.5613041441684821 1.082615296887953 0.2789792146826484 1.0 0.4886556079739165 7 O75608,O95865 2
Sealing of the nuclear envelope ne by escrt iii 0.5106099175829769 1.0806131037217368 0.2798692511873679 1.0 0.4889751013159829 10 Q9BUF5,P04350,P68371,Q8WUX9 4
Rnd3 gtpase cycle 0.4415396792177961 1.0792052640663008 0.2804962335356036 1.0 0.489451761043187 16 P15924 1
Apoptosis 0.2828199534961633 1.0720325569987748 0.2837054091992654 1.0 0.4938046291100565 91 Q15149,P42574,P49720,P15924,Q9UL46,P25789,P25787,P49721,Q06323,P35998,O14727,P35222,Q9UDY2,P28482,Q96FJ2,P02545,Q13546,P55212,Q04917,O00429,P28072 21
Protein folding 0.3481013190158129 1.06768959536173 0.2856605533401313 1.0 0.4953361163313192 33 P40763,P48643,P68371,Q15813,Q9Y2T2,P61758,Q13885,P67870,Q99426,Q9BUF5,P19784,Q9BUR4,Q15477,P04350 14
Fanconi anemia pathway 0.5568561041719816 1.0616619991493272 0.2883891566387668 1.0 0.4993613286048508 7 P35244 1
Signaling by scf kit 0.4807997183054155 1.060967745436624 0.2887045597360895 1.0 0.4993613286048508 12 P40763,P07947,P07948,Q13322,O14757,P22681,P12931,Q06124 8
Rho gtpase effectors 0.2527232754898527 1.0539507498523395 0.2919054660943525 1.0 0.5025198085236064 118 P16333,P62140,Q9Y6W5,Q9UQB8,P60953,O75116,P35222,P55735,Q7Z406,Q96EA4,P28482,Q13409,O14974,Q96FJ2,P12931,Q9BUF5,Q9P258,P08134,Q9HD26,Q13526,P43034,Q92747,Q2NKX8,Q04917,O15144,Q86VI3,P04350,O15145,O43237,P61160,Q15691,Q9Y6G9,O43684 33
Programmed cell death 0.2716302539656955 1.0385302258694704 0.2990232708271918 1.0 0.5102425912937625 101 Q15149,P42574,P49720,P15924,Q9UL46,P25789,P25787,P49721,Q06323,P35998,O14727,P35222,Q9UDY2,O00233,P28482,Q96FJ2,P02545,Q13546,P55212,P25788,Q04917,Q8WUX9,Q9UNE7,O00429,P28072 25
Regulation of tp53 activity 0.2837710191027516 1.028385624300042 0.3037684680547245 1.0 0.516369031797822 53 P35249,Q13547,P54646,P49848,P67870,Q92769,O14744,O14757,Q8TBX8,P35250,Q93009,P27694,Q13526,Q8N0Z6,P40938,P24941,Q92547,P35244,Q8WXI9,P30154,Q00535,P38398,P19784,P06493 24
Biosynthesis of the n glycan precursor dolichol lipid linked oligosaccharide llo and transfer to a nascent protein 0.3878153417465501 1.026163112785055 0.3048147053651182 1.0 0.5175109616886897 22 O14772,Q9Y673,O95394,P34949,Q86YN1,O75340,Q9UJ70,O60547,P10619,Q9NR45,Q2TAA5,Q06210,Q96EK6 13
Ret signaling 0.5446575912473068 1.0044162766029914 0.3151780078247737 1.0 0.5318388361585314 7 P12931,Q13322 2
Synthesis of active ubiquitin roles of e1 and e2 enzymes 0.5125239037199462 1.002793201765532 0.315960649600403 1.0 0.5325092899362891 9 P68036,Q96BN8,Q93009,A0AVT1,P60604 5
Insulin processing 0.5436487782673345 0.9996982381149256 0.3174565649807523 1.0 0.5343787732075514 7 O60645,Q96KP1 2
Dna double strand break repair 0.2820791972657478 0.9960970670998974 0.3192029847689976 1.0 0.5366133190965077 55 P35244,Q9Y2S7,Q9NXR7,Q99504,Q9NWV8,Q9UGN5,O00213 7
Camk iv mediated phosphorylation of creb 0.5055352551464132 0.9953612273399408 0.3195606089843892 1.0 0.5366133190965077 3 Q13555 1
Dna double strand break response 0.3870361488823565 0.982933332542847 0.3256402512977003 1.0 0.545496760355663 21 Q99504,O00213,Q9NWV8 3
Prolonged erk activation events 0.5475320128116737 0.9790977209228025 0.3275316976426254 1.0 0.5473383387449919 5 P46109,P28482 2
Sema4d in semaphorin signaling 0.4784298839638904 0.9764744614820432 0.3288293975827376 1.0 0.5488432698784341 11 Q7Z406 1
Platelet activation signaling and aggregation 0.2787823906961694 0.972282917655337 0.3309098197041571 1.0 0.5516494219917312 53 P61586,P12814,Q06124,Q14344,Q9BWS9,P60953,Q15833,P28482,P12931,Q13685,P41240,P07602,Q12846,P07948,Q8NBF2,P63096,Q8NCG7,Q9NTK5,Q8NBX0,Q9NUQ9 20
Platelet sensitization by ldl 0.5514018691588712 0.9668692453282808 0.3336094027979384 1.0 0.5548113052548145 6 Q16539,P30154,P30153,Q06124,Q16537 5
Trna processing in the mitochondrion 0.5376221538544623 0.9640086767386576 0.3350415757575364 1.0 0.5565233866549464 4 Q9BQ52,O15091 2
Dna damage bypass 0.3428289815385272 0.9573812401809232 0.3383748637143133 1.0 0.5600407923990193 30 O94782,P27694,Q9NZJ0,P35244,P35249,Q9Y2S7,P56282,P40938,Q9NR33,P35250,P49005,Q15054,P40937,P62877 14
Synthesis secretion and inactivation of glucagon like peptide 1 glp 1 0.5419417414764908 0.9537815046080108 0.3401942534078261 1.0 0.560390307329939 5 P35222 1
Incretin synthesis secretion and inactivation 0.5419417414764908 0.9537815046080108 0.3401942534078261 1.0 0.560390307329939 5 P35222 1
Eph ephrin signaling 0.3347691199501021 0.9535038986895976 0.3403348217784683 1.0 0.560390307329939 33 P60953,O75116,P61160,Q7Z406,P07947,P07948,P12931,O15144,O15145 9
Thrombin signalling through proteinase activated receptors pars 0.5478975585345459 0.951107401995524 0.3415498576003297 1.0 0.560390307329939 6 P12931,P62879,P28482,Q14344 4
Response of eif2ak1 hri to heme deficiency 0.5412280043866364 0.95055567693881 0.3418299776260047 1.0 0.560390307329939 5 Q13322,P08243,P05198 3
Assembly and cell surface presentation of nmda receptors 0.4730843226598816 0.9478057281905546 0.3432283638681523 1.0 0.5620161124002211 11 P68371,Q13555,Q9NUP9,Q13885,Q9BUF5,Q92796,P04350 7
Aurka activation by tpx2 0.3437243696152814 0.9460306534211904 0.3441329517206426 1.0 0.5628304606839386 29 O75935,Q13561,Q9H6D7,Q15691,Q14203,Q13409,P43034,P07437,Q96CS2,P04350,Q9NVX0 11
Post chaperonin tubulin folding pathway 0.497339162294881 0.9268564118808484 0.3540010909608768 1.0 0.5748877881409304 9 P68371,Q15813,Q99426,Q9BUF5,P04350 5
Nuclear events kinase and transcription factor activation 0.4808063292639091 0.9249003854925522 0.3550177260915821 1.0 0.5751869841249313 10 P51452,Q00535,P50570,P28482 4
Toll like receptor tlr1 tlr2 cascade 0.4162009980070617 0.9211474100394708 0.3569734706751308 1.0 0.577678379945001 16 Q02750,O15111,P28482,Q13616,P30154,P51452,P63208 7
Activated notch1 transmits signal to the nucleus 0.4530180460485505 0.9200319222134608 0.3575560777995354 1.0 0.5778022097001916 2 P32121 1
Listeria monocytogenes entry into host cells 0.511089185721507 0.91798587696151 0.3586262597980156 1.0 0.5783214597909657 8 P12931,P35222 2
Constitutive signaling by akt1 e17k in cancer 0.5338046804998356 0.9170983353805704 0.359091113276492 1.0 0.5783961754639999 5 O15111,Q96B36 2
Sulfur amino acid metabolism 0.4948413279794669 0.9144509176309632 0.3604799572783337 1.0 0.5799572770182273 9 P25325,Q13126 2
Late endosomal microautophagy 0.5097731942930583 0.9116928047620722 0.3619304527251121 1.0 0.5807731500202684 8 P08670,Q99816,Q8WUX9 3
Telomere maintenance 0.3024359625162016 0.9063728519564944 0.3647385370985492 1.0 0.5827383332603411 43 P39748,P35249,Q9BUR4,Q15054,Q9NPE3,P09884,Q14181,P18858,P35250,P27694,P40937,P49643,Q9Y2S7,P40938,P24941,Q15554,O00743,P35244,Q8WVB6,P49005 20
Inhibition of replication initiation of damaged dna by rb1 e2f1 0.5233097665979826 0.905230395631227 0.3653433421889265 1.0 0.5828621423398125 7 Q14181,P30154,P49643,P09884 4
Recycling pathway of l1 0.383566498678523 0.9022871851504332 0.3669043311837727 1.0 0.5828621423398125 20 P68371,P50570,P28482,P12931,Q13885,Q9BUF5,P26038,Q16555,P04350,P53680 10
Mapk targets nuclear events mediated by map kinases 0.5226627862248695 0.90224865687556 0.3669247929346142 1.0 0.5828621423398125 7 Q16539,P28482,P30154,P30153,P51452 5
Erk mapk targets 0.5226627862248695 0.90224865687556 0.3669247929346142 1.0 0.5828621423398125 7 Q16539,P28482,P30154,P30153,P51452 5
Apoptotic execution phase 0.3280598350860266 0.8969563243120331 0.3697422231298906 1.0 0.5859905417035651 33 Q15149,P55212,P15924,P35222,P02545,O00429 6
Apoptotic cleavage of cellular proteins 0.3734581137692458 0.8881764250624657 0.3744458578768899 1.0 0.5927653786779631 21 Q15149,P55212,P15924,P35222,P02545 5
Oxidative stress induced senescence 0.4170713501175833 0.8856381384939802 0.3758125531288554 1.0 0.5942482247415083 15 O75530,P28482,Q00534 3
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.4721742505549113 0.8804764713773741 0.3786012458099175 1.0 0.5946501026194838 10 O15047,Q99873 2
Spry regulation of fgf signaling 0.51790876640829 0.8803893921472737 0.3786484010891069 1.0 0.5946501026194838 7 P12931,Q06124,P28482 3
Negative regulation of fgfr1 signaling 0.51790876640829 0.8803893921472737 0.3786484010891069 1.0 0.5946501026194838 7 P12931,Q06124,P28482 3
Negative regulation of fgfr2 signaling 0.51790876640829 0.8803893921472737 0.3786484010891069 1.0 0.5946501026194838 7 P12931,Q06124,P28482 3
Negative regulation of fgfr3 signaling 0.51790876640829 0.8803893921472737 0.3786484010891069 1.0 0.5946501026194838 7 P12931,Q06124,P28482 3
Negative regulation of fgfr4 signaling 0.51790876640829 0.8803893921472737 0.3786484010891069 1.0 0.5946501026194838 7 P12931,Q06124,P28482 3
Dna damage reversal 0.5240425198831464 0.8733863334971923 0.3824525375491934 1.0 0.5987908848285646 5 Q9C0B1 1
Endosomal sorting complex required for transport escrt 0.5016783332100084 0.8731434121451952 0.3825849141126067 1.0 0.5987908848285646 8 Q99816 1
Copi dependent golgi to er retrograde traffic 0.2893410823726923 0.8669225088304736 0.3859844696641326 1.0 0.6027463695772104 46 P68371,Q14807,P84085,O14579,Q92538,Q9H0U4,Q13885,Q9BUF5,Q9BVK6,P52732,P61923,Q8N6T3,P04350,Q99747,Q07866,O95239,O43264,Q12756,Q15363,Q9Y496 20
Muscle contraction 0.3546021273910431 0.8639687258459632 0.387605070901021 1.0 0.6044035823869908 24 P23634,P04083,P07355 3
Egfr downregulation 0.5279301492760402 0.8620632623439736 0.388652706267734 1.0 0.604862657727487 6 P60953,Q99961,P42566,Q9Y6I3 4
Crmps in sema3a signaling 0.51224911034722 0.8544890129802033 0.3928340945074786 1.0 0.6106824731263617 7 P49841,Q16555,Q9BPU6,Q14195,Q00535 5
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.5130759651307577 0.8532083965039632 0.3935437479108508 1.0 0.6110982692278605 4 P30154,P30153,Q14738 3
Toll like receptor 9 tlr9 cascade 0.3907378272770513 0.8501711922886213 0.3952299154326162 1.0 0.6129220588698346 18 Q99570,Q02750,O15111,Q16539,P28482,Q13616,P09429,P30154,P30153,P51452,P63208 11
Cd163 mediating an anti inflammatory response 0.4393279402613674 0.8492129623031348 0.3957628017648777 1.0 0.6129220588698346 2 Q16539 1
Dna repair 0.2362204947355612 0.8398490933396922 0.4009930033800124 1.0 0.6198795645091467 120 Q9C0B1,Q9NWV8,P18074,O94782,O00213,P62877,Q9NZJ0,Q9UBW8,Q9NXR7,O14757,P18858,Q9NR33,Q93009,Q92905,P29372,Q9Y2S7,Q99504,P40938,P24941,Q86W56,Q92547,P27695,P35244,O95551,Q6P6C2,Q9UNS2,P38398,P49005,Q9UGN5 29
Cargo concentration in the er 0.4085706165452947 0.8350294496152291 0.4037011272623187 1.0 0.6226729440586212 15 P53634,Q9H0V9,Q15363,Q13190 4
Gab1 signalosome 0.5085915263080899 0.8332138465805664 0.4047241347504218 1.0 0.6235549099499252 4 P12931,Q06124 2
Growth hormone receptor signaling 0.5130192645363587 0.8244814797053054 0.4096660347933345 1.0 0.6276701331312509 5 P40763,P07948,P28482 3
Tp53 regulates transcription of genes involved in g2 cell cycle arrest 0.5046204048929969 0.8198094937509501 0.4123247180690779 1.0 0.6294433851812075 7 Q99873,Q86X55,P12004,P14635,P06493 5
Transcription coupled nucleotide excision repair tc ner 0.27112111690122 0.8170165765118733 0.413918955061259 1.0 0.6299955901923567 50 P35249,Q15054,P18074,Q9UBW8,P62877,P18858,P35250,Q93009,Q9NR33,P27694,Q92905,P40937,Q9Y2S7,P56282,P40938,Q9BT78,P35244,Q9UNS2,P49005 19
Negative regulation of nmda receptor mediated neuronal transmission 0.516892988844644 0.8135138152555592 0.4159235287096243 1.0 0.6323501833627072 6 Q13555,Q92796,P49593 3
Cell cycle 0.2135810953219387 0.788147922516948 0.4306101866310601 1.0 0.6491380248747397 305 Q9NWV8,P67870,P25787,Q9NPE3,Q96EA4,O14757,O14974,P02545,P07437,P18858,P49736,P04818,Q99460,Q9Y2S7,Q7Z5K2,O00743,P28074,P35244,O43237,Q9UH99,Q15691,P04183,Q8WVB6,Q92530,Q9UL46,O75832,P55036,Q06323,P62877,Q9NXR7,Q96CW5,Q13409,Q9H0U4,P12931,Q9NR33,P07948,P54652,P40938,P43034,Q92547,Q2NKX8,Q04917,P04350,O43929,Q9H6D7,Q96CS2,O43684,P49005,P19784,P14635,P62140,P49720,P39748,Q13547,P68371,Q13561,Q96GX5,Q9BRX5,Q14203,Q92973,P25789,P49721,Q9BUR4,Q9NVX0,P55735,P28482,P09884,Q96FJ2,Q9BUF5,P21127,P20618,P35250,Q9P258,O60566,P49643,O43913,O95067,P56282,Q99436,Q13616,P30154,O00231,P06493,P28072,P62333,P35249,Q92674,Q16537,Q15054,P35998,O75935,Q9UNM6,Q9UIC8,O00233,Q00534,Q14674,Q14181,Q99986,Q13885,Q9BWT6,P27694,P31350,P40937,Q9UBD5,Q9UJX5,P63151,P25788,P24941,Q13309,P63208,Q8WUX9,Q9Y6G9,Q9Y570,P38398,P11802 115
Assembly of the orc complex at the origin of replication 0.4969015577895458 0.785020052581729 0.4324418116259687 1.0 0.6510180649968287 7 O43929,O43913,O60684,Q9UBD5 4
Signaling by ntrk2 trkb 0.4964748757678761 0.783106424167387 0.4335646190089406 1.0 0.6519981539394516 7 Q00535,P12931 2
Regulation of kit signaling 0.5030427633483363 0.7807028748074525 0.4349772694116938 1.0 0.6527020481291649 5 P07947,P12931 2
Traf6 mediated irf7 activation 0.4953311814967593 0.7746430812247148 0.4385505930346742 1.0 0.6566380493758611 4 Q12933,Q7Z434 2
Retrograde transport at the trans golgi network 0.4496239618973621 0.7664666300569435 0.4433987001188804 1.0 0.6610323663045229 10 Q9UID3,Q9UP83,Q96JB2,Q99747,P40616 5
Cd28 co stimulation 0.4629604934750271 0.7589461011970206 0.447884799655637 1.0 0.6662828774209799 9 P60953,P12931,P07947 3
Interleukin 4 and interleukin 13 signaling 0.4254694296016217 0.7579442363418664 0.4484843665129436 1.0 0.6664574134633205 12 P04083 1
Hdr through homologous recombination hrr 0.3286263623691838 0.7537607728507443 0.4509928824552478 1.0 0.669465266974385 26 P27694,P35244,P35249,Q9Y2S7,P49005,P56282,O14757,P40938,Q9NR33,P35250,Q92547,P38398,Q15054,P40937 14
Neurotransmitter receptors and postsynaptic signal transmission 0.2946321188273302 0.7434290855385985 0.4572219404637891 1.0 0.6757191183053921 39 P68371,P54646,Q13555,Q9NUP9,P62879,P28482,P49593,P12931,Q13885,Q9BUF5,Q92796,P63096,Q13557,P04350 14
Thromboxane signalling through tp receptor 0.4880142008146657 0.7427210626332764 0.4576505750606707 1.0 0.6757191183053921 4 Q13685,Q14344 2
Advanced glycosylation endproduct receptor signaling 0.4974321064355288 0.7293865383630977 0.4657652499366738 1.0 0.6855032751996627 6 P47755 1
Antigen activates b cell receptor bcr leading to generation of second messengers 0.4841194271393413 0.7258573194170622 0.4679262436149685 1.0 0.6879511368892409 4 P16333,P07948 2
Unwinding of dna 0.4697468518518678 0.7244258836724631 0.468804313927023 1.0 0.6885096300182209 8 Q9BRT9,P33991,Q9BRX5,Q14566,P49736 5
Transcription of e2f targets under negative control by p107 rbl1 and p130 rbl2 in complex with hdac1 0.4470060062178422 0.7159935486237577 0.4739953324763104 1.0 0.6946569983905206 3 Q13547 1
Glycogen synthesis 0.4867540002457074 0.7103916555051072 0.477461296316704 1.0 0.6989952452433104 5 Q96G03,P13807,Q16851 3
Gap junction trafficking and regulation 0.4155839136452621 0.7061259655382147 0.4801098055817179 1.0 0.6996071337728558 12 P68371,P50570,P12931,Q9BUF5,P04350 5
Semaphorin interactions 0.3218287477930511 0.7043379202316575 0.4812223565513758 1.0 0.7000518913200015 26 Q7Z406,P08134,Q14195 3
Adrenaline noradrenaline inhibits insulin secretion 0.4779743892793069 0.6994449907863014 0.4842739793867787 1.0 0.7037504095820486 4 P63096 1
Rho gtpase cycle 0.2239469317710636 0.6984404082411506 0.4849018132192539 1.0 0.7039225901985389 162 P11182,Q13492,P15924,Q9HD26,P14923,Q5VTR2,Q9UDY2,Q15208,Q9Y6W5,P08134,Q8IW35 11
Bbsome mediated cargo targeting to cilium 0.4635095018966326 0.6961501107236859 0.4863348272285974 1.0 0.7048520159758562 8 Q9H0F7 1
Iron uptake and transport 0.3723503447921252 0.6957872090995272 0.4865621007532321 1.0 0.7048520159758562 17 P21399,O76003,P36543,P09601,Q15904,P30519,Q13616,P38606,P21281,P63208 10
Uptake and function of diphtheria toxin 0.4762327542566869 0.6920046562109707 0.4889344049187498 1.0 0.7068068489515819 4 P13639 1
Cooperation of pdcl phlp1 and tric cct in g protein beta folding 0.4097271966170533 0.6758950190500679 0.4991073003884276 1.0 0.7185065511841741 12 P67870,P19784 2
Rho gtpases activate formins 0.2548815792995829 0.6709178656594201 0.5022728544026016 1.0 0.7206912700963423 61 O43237,P55735,Q96EA4,Q96FJ2,P12931,Q9BUF5,P04350,Q2NKX8,P08134 9
Signaling by receptor tyrosine kinases 0.2256054893771101 0.6659323644069499 0.5054543326859133 1.0 0.7232016596312021 119 P16333,Q13547,P14923,P04792,Q13322,Q8WX92,Q06124,Q9Y6W5,Q9BUB5,Q9UQB8,P38606,P60953,O75116,P35222,P50570,Q92769,P28482,O14757,P12931,P46109,P40763,Q9Y6I3,Q02750,P07947,P07948,P52597,P51452,Q96S59,P30154,Q9UNE7,Q16543,O43865,Q00535,P42566 34
Signaling by ntrks 0.3037653587282845 0.6658475619725045 0.505508540668409 1.0 0.7232016596312021 31 P40763,Q02750,P50570,Q8WX92,P28482,P12931,P30154,Q06124,P51452,Q00535,P46109 11
Ddx58 ifih1 mediated induction of interferon alpha beta 0.3725507629219018 0.6612344533053675 0.5084619694010164 1.0 0.7257682861020154 16 Q15366,Q13546,Q7Z434,Q13526 4
Translesion synthesis by y family dna polymerases bypasses lesions on dna template 0.3345306393625316 0.657220341202857 0.5110392480755803 1.0 0.7273493726472214 22 P35244,P35249,Q9Y2S7,P56282,P40938,Q9NR33,P35250,P49005,P27694,P40937,Q15054 11
Signaling by rho gtpases miro gtpases and rhobtb3 0.2119850415311301 0.6549751131644888 0.5124837773488748 1.0 0.7286549180001493 258 P11182,P15924,P14923,Q5VTR2,Q9Y6W5,P35222,Q9UDY2,P55735,Q7Z406,Q96EA4,Q15208,P28482,P52306,Q96FJ2,P12931,Q9BUF5,Q9P258,P08134,Q13492,Q9HD26,Q13526,Q9BZH6,Q99707,Q96P48,Q2NKX8,Q04917,P04350,O43237,P06753,Q8IW35 30
Cytosolic trna aminoacylation 0.329188627850876 0.6519446925207422 0.5144368521308775 1.0 0.7291004450234964 23 Q13155,P41250,Q15181,P49589,Q9Y285,P54136,P26639,P23381 8
Heparan sulfate heparin hs gag metabolism 0.4329287270463826 0.6518829430755978 0.514476689198426 1.0 0.7291004450234964 3 P16278,P54802 2
Long term potentiation 0.4787437630236294 0.6507862620718704 0.5151844695902661 1.0 0.7291004450234964 6 Q13555,P12931,Q92796 3
Clathrin mediated endocytosis 0.2503591694145078 0.6502635946110703 0.5155219686523242 1.0 0.7291004450234964 56 P51809,Q9UKS6,O14976,Q9NVZ3,Q99961,Q9UBW8,Q14247,O00443,P50570,Q92905,P61020,Q13492,Q9Y6I3,P61158,Q92747,Q8N6T3,O15144,O15145,Q9BT78,P52594,P61160,P62330,Q9UNS2,P20339,P42566,P25098,P53680 27
Signaling by ntrk3 trkc 0.4702682269016709 0.6409923372994263 0.5215276614933897 1.0 0.7347107320936438 5 P12931 1
Regulation of tp53 expression and degradation 0.4370181384100763 0.6376492332056547 0.5237020393562726 1.0 0.736272856958666 9 P30154,P24941,Q93009 3
Translesion synthesis by polk 0.4366245836622996 0.6358555296031119 0.5248705901042268 1.0 0.7371658084593917 9 P35244,P35249,P40938,P35250,P27694,P40937 6
Insulin receptor signalling cascade 0.4744411139509926 0.6330476154093936 0.5267025492763646 1.0 0.7389877391877522 6 Q13322,P28482 2
Negative regulators of ddx58 ifih1 signaling 0.4352712792866273 0.6296993818551999 0.5288912870718314 1.0 0.7413060433400315 9 Q15366,Q7Z434,Q13526 3
Cytosolic sulfonation of small molecules 0.4667647600913252 0.6265065657821962 0.5309827316777089 1.0 0.7434834196338336 5 Q96IU4,O95340,O95861 3
Cytosolic iron sulfur cluster assembly 0.4464228768799811 0.6203240991020099 0.5350444319261876 1.0 0.7469004090121124 8 O76071,P18074,Q6FI81 3
Deactivation of the beta catenin transactivating complex 0.4315339517174871 0.6127954045284141 0.5400116298497466 1.0 0.7504619789730438 9 Q9UBL3,P35222,Q15291 3
Signaling by pdgf 0.43138326626817 0.6121169006516886 0.5404604164778002 1.0 0.7504619789730438 9 P16333,P12931,Q06124,P46109 4
Downstream signal transduction 0.43138326626817 0.6121169006516886 0.5404604164778002 1.0 0.7504619789730438 9 P16333,P12931,Q06124,P46109 4
Regulation of signaling by cbl 0.4631149011681862 0.6115221941559653 0.5408539298532211 1.0 0.7504619789730438 5 P07947,P07948,P46109 3
Opioid signalling 0.3218385689588698 0.6039331742936619 0.545888071893565 1.0 0.7555789996257524 23 Q13555,P63096,P62879,P28482,P30154,P62136,O43865,Q00535,Q08209,Q13557,P25098 11
G beta gamma signalling through pi3kgamma 0.4220452949928154 0.6034912642836391 0.5461819251998021 1.0 0.7555789996257524 3 P61586 1
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.2425533453065431 0.5998964447767619 0.5485752519403873 1.0 0.7581309981816152 52 P62847,Q9Y262,P60866,P62857,Q7L2H7,P62244,P08708,P62081,P62854,P23396,P62841,P15880,P62753,P06730,P25398,P56537,P62269,O75821 18
Signal regulatory protein family interactions 0.4584379545538929 0.592487088381717 0.5535244642817987 1.0 0.7588996127355613 5 P12931 1
Processing of dna double strand break ends 0.2985301485650471 0.5771109333749802 0.5638645189584865 1.0 0.7705079186295569 27 P35244,P35249,Q9NXR7,O14757,Q9NWV8,P40938,P24941,P35250,Q92547,P38398,P27694 11
Adp signalling through p2y purinoceptor 12 0.4540818991656943 0.5749331780283858 0.5653364902245808 1.0 0.7705079186295569 5 P63096 1
Gaba b receptor activation 0.4540818991656943 0.5749331780283858 0.5653364902245808 1.0 0.7705079186295569 5 P63096 1
Gaba receptor activation 0.4540818991656943 0.5749331780283858 0.5653364902245808 1.0 0.7705079186295569 5 P63096 1
Mitophagy 0.4085680936381081 0.5698130709730466 0.5688044892023245 1.0 0.772188412649914 10 P12931,P67870,P19784 3
Signaling by csf3 g csf 0.4337617069976056 0.5659104397833805 0.5714546643213017 1.0 0.7735067052811351 8 P40763,Q15369,P07948,Q06124,P42224 5
Repression of wnt target genes 0.4436525187095103 0.5571623607677486 0.5774165035858503 1.0 0.7799379264770987 4 Q13547,Q13363 2
Eukaryotic translation initiation 0.2340729908453032 0.5546059729591428 0.5791642026556167 1.0 0.7808828566537194 101 P62899,P25398,Q13144,Q9Y262,P60866,P49770,P42766,P62081,P08708,P46778,P62847,P84098,P27635,P62910,P05388,P62857,Q7L2H7,P62244,P26373,P23396,P62841,P15880,P56537,P62269,P46777,P62906,P55010,P61513,P62854,P62753,Q9UI10,P06730,O75821,Q9NR50 34
Polo like kinase mediated events 0.4474865261414815 0.5486942264804919 0.5832153090121639 1.0 0.782984216681965 5 O95067 1
Nucleotide excision repair 0.2414309853075191 0.5485316304927401 0.5833269166062691 1.0 0.782984216681965 59 P35249,Q15054,P18074,Q9UBW8,P62877,P18858,P35250,Q93009,Q9NR33,P27694,Q92905,P40937,Q9Y2S7,P56282,P40938,Q9BT78,P35244,Q9UNS2,P49005,Q9UGN5 20
Condensation of prometaphase chromosomes 0.4027071871017331 0.5432765000512009 0.5869394418515839 1.0 0.7867607261288933 10 O95067,P67870,P14635,P19784 4
Diseases of mitotic cell cycle 0.3494318362582891 0.534121660255004 0.5932573647452686 1.0 0.7913915811563332 16 Q13309,Q9UJX5,P24941,Q00534 4
Factors involved in megakaryocyte development and platelet production 0.2601008896434473 0.5317177948856805 0.5949214652986246 1.0 0.7920823362646426 43 Q13547,Q13572,P68371,P47755,Q14807,P60953,Q92769,Q13885,Q9BUF5,Q92667,P52732,P24941,P47756,P04350,P13861,Q07866,Q9H4M9,O95239,P20339,Q00535,Q9Y496 21
Signaling by moderate kinase activity braf mutants 0.3410782706502978 0.5193453391554952 0.6035199415413057 1.0 0.8027570348508993 17 Q02750,Q13555,P28482,P10398,P30086,P12931,P41240 7
P75 ntr receptor mediated signalling 0.3549016454830981 0.5089878643136964 0.6107607305385263 1.0 0.810827405959888 14 P42574,Q13547,P61586,Q92769,Q92974,P42575 6
Signaling by insulin receptor 0.3496724842351486 0.5078887903392088 0.6115313364524104 1.0 0.8110713118783409 15 Q13322,P28482,P38606 3
Rhob gtpase cycle 0.2972344317891829 0.5050434072321539 0.6135283486457037 1.0 0.8120170724758209 25 P14923 1
Cellular response to starvation 0.2361185319501652 0.5041046635265668 0.6141878299604828 1.0 0.8120170724758209 90 P62847,P62899,P84098,P05388,P62910,P55735,Q8NFG4,P42766,P62081,P62244,P62841,P62753,P38606 13
Telomere extension by telomerase 0.3745497758123522 0.5035257409324397 0.6145946872718586 1.0 0.8120170724758209 12 Q9BUR4,P24941,Q9NPE3 3
Rho gtpases activate paks 0.3738047064994972 0.5000760557571744 0.6170215252802658 1.0 0.8126273267566805 12 P60953,Q7Z406,O14974 3
Pyroptosis 0.4405251517218161 0.4989625487100584 0.6178057680733047 1.0 0.8126273267566805 6 P42574 1
Rab regulation of trafficking 0.2698625312829298 0.4970450472670952 0.6191572850493217 1.0 0.8126273267566805 36 P60520,P61020,Q9NVG8,Q4KMP7,P62330,Q9Y3P9,Q9BXI6,Q9H0U4,P20336,Q9UJY4,P20339 11
Rrna processing in the mitochondrion 0.4169973529880989 0.4966009839705873 0.6194704591282711 1.0 0.8126273267566805 8 Q8WVM0,Q9BQ52,O15091,Q9UI43 4
Folding of actin by cct tric 0.4155236907730752 0.4906733275996314 0.6236575141937246 1.0 0.8126273267566805 8 P50990,P48643,P40227,P78371,Q99832,P17987,P49368 7
Rhobtb3 atpase cycle 0.3949579831932769 0.488489506026862 0.6252031569874179 1.0 0.8135882890363574 3 Q13618,O60664 2
Anti inflammatory response favouring leishmania parasite infection 0.3334022958878282 0.4790162996270014 0.6319270330451063 1.0 0.821331006860406 17 P07947,P07948,P13861,P62879,P12931,O43865,P63096,Q9Y3E5 8
Trna modification in the mitochondrion 0.4124036099970006 0.4782170354514141 0.6324957388112948 1.0 0.821331006860406 8 O15091,O75648 2
Rho gtpases activate nadph oxidases 0.4236024874314829 0.4769083296142005 0.633427400311734 1.0 0.821331006860406 7 P28482 1
Ncam signaling for neurite out growth 0.3999237739099498 0.476353663619921 0.6338224399873507 1.0 0.821331006860406 9 P12931,P28482 2
Pkmts methylate histone lysines 0.3576498459292571 0.4717313576066334 0.6371185517626321 1.0 0.8238728994883235 13 O15047,O75530 2
Hemostasis 0.209025484442815 0.4715060516825489 0.6372793990976975 1.0 0.8238728994883235 120 P42785,Q13547,Q13572,P68371,P61586,P47755,P12814,Q06124,Q14344,P78310,Q16537,Q14807,Q9BWS9,P60953,Q15833,Q92769,P28482,P12931,Q13885,Q9BUF5,Q13685,P35237,P41240,P07602,P14174,Q12846,P07947,P07948,P52732,P24941,Q8NBF2,P47756,P63096,P04350,Q8NCG7,Q9NTK5,Q8NBX0,Q92896,Q9H4M9,Q9NUQ9,P30154,P23634,P07355,Q00535,Q9Y496 45
Eukaryotic translation elongation 0.2366071970663724 0.4702682445915404 0.6381633821249726 1.0 0.8242446673801048 77 P62847,P62899,P84098,P05388,P62910,P42766,P62081,P62244,Q05639,P62841,P62753,P13639 12
Signaling by fgfr3 0.3971136910625733 0.4648673893637849 0.6420264249998648 1.0 0.8269156750697234 9 P12931,Q06124,P28482 3
Signaling by fgfr1 0.3971136910625733 0.4648673893637849 0.6420264249998648 1.0 0.8269156750697234 9 P12931,Q06124,P28482 3
Signaling by fgfr4 0.3971136910625733 0.4648673893637849 0.6420264249998648 1.0 0.8269156750697234 9 P12931,Q06124,P28482 3
Netrin 1 signaling 0.3657365337970626 0.463343947703333 0.6431178493225662 1.0 0.8269554698238126 12 P16333,P12931,Q06124 3
Runx2 regulates bone development 0.4199959016075986 0.4631538771014189 0.6432540738499266 1.0 0.8269554698238126 7 P07947,P12931,P28482 3
Prevention of phagosomal lysosomal fusion 0.4174579558012493 0.4561572697715357 0.6482768900876528 1.0 0.8314240929239923 4 Q9H267,P31146 2
Transcriptional regulation by tp53 0.2013667524352099 0.4557985361741528 0.6485348568538811 1.0 0.8314240929239923 125 Q15369,Q13547,Q8IXH7,Q99873,P35249,P54646,P50750,P49848,Q8WX92,P67870,Q86X55,P18074,Q14241,O14727,P32119,Q92769,Q9NQ88,O14744,O14757,P42575,P35250,Q93009,Q8TBX8,P27694,P43246,P55212,Q13526,Q9H3P2,Q8N0Z6,P40938,P24941,Q92547,Q04917,P11413,P35244,Q8WXI9,Q16881,Q9UIV1,P30154,P19784,O43819,Q00535,P38398,P14635,P06493 45
Signaling by alk 0.4268924350684818 0.4484540779092378 0.6538255211391932 1.0 0.8362029529643689 6 P12931,Q92769,Q13547 3
Meiotic recombination 0.3623102490251478 0.448104600822817 0.6540777077818254 1.0 0.8362029529643689 12 P38398,P35244,P24941,Q9BWT6 4
Nuclear events stimulated by alk signaling in cancer 0.360869774772958 0.4417643582997802 0.6586597325016643 1.0 0.839730396971679 12 P40763,P28482,P62753,Q86WB0,P63208,P62877 6
Cellular response to chemical stress 0.2330898940515993 0.4398820670243286 0.6600225248257039 1.0 0.8406922850775326 78 P49720,P28072,Q9UL46,O75832,P25789,P67870,Q86X55,P25787,P49721,P55036,Q06323,P35998,P62877,P32119,O00233,P20618,P40763,Q99460,P25788,Q13309,P63208,P28074,Q99436,Q16881,Q13616,O43819,O00231,Q92530,P19784,P30041 30
Trna aminoacylation 0.2570557907642313 0.4356520744473904 0.6630891825481231 1.0 0.8416185335426661 38 P49591,P49590,P41250,Q9H2U2,Q13155,Q15181,P49589,Q7L3T8,Q96I59,Q9Y285,Q96GW9,P54136,Q5JPH6,P26639,P23381 15
Cooperation of prefoldin and tric cct in actin and tubulin folding 0.3300010669554596 0.4355191242115052 0.6631856606569924 1.0 0.8416185335426661 16 P48643,P68371,P61758,Q9BUF5,P04350 5
Dna replication initiation 0.3991598679959584 0.4268402002764971 0.6694957238558126 1.0 0.8488468718979202 8 P56282,P09884,Q14181,Q9NR33,P49643 5
Regulation of ifng signaling 0.4087432917892608 0.4243537061954385 0.6713078770926633 1.0 0.8503643319358942 4 P42224,Q06124 2
Rho gtpases activate pkns 0.3099789617033614 0.4164693815646192 0.6770665678296974 1.0 0.8553071268195994 19 Q7Z406,P08134 2
Senescence associated secretory phenotype sasp 0.3205825973178123 0.4148549134043443 0.678248117240305 1.0 0.8560172584713256 17 Q9UJX5,P24941,P28482,Q00534 4
Formation of the beta catenin tcf transactivating complex 0.3697513429025273 0.4035664987187003 0.6865315252302213 1.0 0.8613418149770004 10 P35222 1
Regulation of ifna signaling 0.3732439016208839 0.4031736239826567 0.6868205018435305 1.0 0.8613418149770004 3 Q06124 1
Pi3k akt signaling in cancer 0.3509275331681235 0.3991287789446295 0.6897983179223997 1.0 0.8642128580997154 12 P12931,Q96B36 2
Signaling by tgf beta receptor complex 0.2930336398934096 0.3899737239598844 0.6965559769865082 1.0 0.8695938213146832 21 P62140,Q13547,P61586,P61081,P62942,P28482,Q9UNE7,Q9Y5K5,P62136 9
Signaling by kit in disease 0.3980662330266973 0.3833112815299351 0.701488975448241 1.0 0.8749618809291236 7 P40763,P07948,P12931,P07947 4
Signaling by hippo 0.4055036972192204 0.3739528073714162 0.7084394272764314 1.0 0.8820389986450705 6 Q9UDY2 1
Signaling by mras complex mutants 0.39938559870071 0.3721796768794259 0.7097590764821131 1.0 0.8828866279912514 5 P10398 1
Activated tak1 mediates p38 mapk activation 0.3932129514321273 0.3702271242341146 0.7112132680074394 1.0 0.8828921133833516 4 Q16539,Q13404,P61088 3
Dual incision in tc ner 0.2485240079497449 0.369939294316102 0.7114277225078804 1.0 0.8828921133833516 37 P27694,P35244,P35249,Q9Y2S7,P56282,P40938,Q9NR33,P35250,P49005,Q15054,P40937,Q93009,P18074,P62877 14
Mitotic prometaphase 0.2221356227706015 0.3690905463213119 0.7120602352079708 1.0 0.8828921133833516 88 Q13561,Q14203,P67870,Q9NVX0,O75935,P55735,Q96EA4,Q96CW5,Q13409,Q96FJ2,P07437,Q9BUF5,Q9P258,O95067,P43034,Q7Z5K2,Q2NKX8,P04350,O43237,Q15691,Q9H6D7,Q9Y6G9,Q96CS2,P19784,O43684,P14635 26
Gamma carboxylation hypusine formation and arylsulfatase activation 0.3509212056515062 0.3632366114464274 0.7164281406529915 1.0 0.8840211521271736 11 Q9BU89,P13639 2
Bmal1 clock npas2 activates circadian gene expression 0.3595137256783228 0.3530181325270248 0.7240748468094931 1.0 0.8902770803298216 3 Q86X55 1
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.3933354095297438 0.3521546453481239 0.7247222887283655 1.0 0.8902810693534233 5 O15111,Q13404,P61088,P09429 4
Glycosphingolipid metabolism 0.3114277119014446 0.3500124167114123 0.7263293791668146 1.0 0.8914628792260549 16 P17900,P07602,Q13510 3
Homologous dna pairing and strand exchange 0.3100783559355838 0.3441748026663616 0.730714830604638 1.0 0.8949174760083967 16 P35244,P35249,O14757,P40938,P35250,Q92547,P38398,P27694 8
Selenoamino acid metabolism 0.2176042520257477 0.3436620033380032 0.7311004895044648 1.0 0.8949174760083967 91 P62899,P60866,P42766,P62081,P08708,P46778,P54136,P62847,Q13155,P84098,P27635,P62910,P05388,P62857,P62244,P26373,P23396,P62841,O43252,P15880,P62269,P46777,P49591,P62906,P61513,P62854,P62753,O95340,Q16881,P25398 30
Diseases of mismatch repair mmr 0.3563647681294719 0.3419717552935246 0.7323721482231274 1.0 0.8949174760083967 3 P52701,P43246 2
Uptake and actions of bacterial toxins 0.3856627022286591 0.3413200192692061 0.7328626786379331 1.0 0.8949174760083967 7 P13639,Q16881 2
Mucopolysaccharidoses 0.3557422969187688 0.3398091509237756 0.7340002561291881 1.0 0.8949174760083967 3 P16278,P54802 2
Response of eif2ak4 gcn2 to amino acid deficiency 0.2206437521698299 0.3395867021324408 0.7341677938003941 1.0 0.8949174760083967 77 P62847,P62841,P42766,P62753 4
Signaling by tgfb family members 0.278122378872188 0.3330798434507225 0.7390740141050667 1.0 0.8979118126506559 22 P62140,Q13547,P61586,P61081,P62942,P28482,Q9UNE7,Q9Y5K5,P62136 9
Extracellular matrix organization 0.2579447452128441 0.3292218815703325 0.7419879848904003 1.0 0.8991752017822677 27 Q15149,P42574,O60568,P07384,Q02809,P12814,P04632,P17655 8
The phototransduction cascade 0.3805437290538112 0.3287130629211984 0.742372579763797 1.0 0.8991752017822677 4 P50579 1
Rhoc gtpase cycle 0.2452993965878442 0.3269081063402867 0.743737389693222 1.0 0.9000394680875944 35 P08134,P14923 2
Potential therapeutics for sars 0.2352593662910961 0.3192547651283057 0.749533331398772 1.0 0.9054677132806844 40 O75116,Q8WXI9,Q92769,P21964,P62942,O75446,Q15185,P07437,P20839,Q13546,P12268,P62877 12
Cellular responses to stimuli 0.1805898799871296 0.3171386849466214 0.751138372409454 1.0 0.9058882759381512 329 P62899,P49720,P04792,Q9UL46,Q13561,Q13451,Q13322,P42766,Q14203,P47755,P62081,P43307,P25789,P67870,P25787,P49721,Q06323,P38606,P35998,P62847,Q99543,O75935,P84098,P05388,P55735,Q9UJW0,P62910,P62857,P32119,O00233,P51858,P28482,P62244,Q00534,Q96FJ2,P02545,Q15185,P62841,Q9BUF5,O75530,O43301,Q9NQT5,Q9UJX5,Q99460,Q96B36,Q8NFG4,P54652,P25788,P24941,P62753,Q13309,P04350,P63208,Q9UL15,O14773,P35244,Q96B26,O43237,Q9Y6G9,O95817,P19784,P28072,P11802 63
Signalling to erks 0.3459806075316348 0.3148552263991108 0.7528715779614903 1.0 0.9066881094537628 10 P46109,P12931,P28482 3
Infectious disease 0.1765517126898466 0.313702200182566 0.7537472295661991 1.0 0.9066881094537628 349 P16333,P42766,P62081,P25787,P62847,P35222,P62910,P62857,P62841,P07437,O75530,P18858,Q99460,Q99816,Q9H3P2,P62753,O15144,P28074,O43237,P61160,P62942,Q92530,P62899,Q99873,Q9UL46,O75832,P08708,Q9Y6W5,P55036,Q06323,P18074,Q14241,P62877,P60953,Q92769,Q13409,P12931,Q9H267,Q13546,P12268,P07947,P07948,P21964,P31146,Q9Y2Z0,Q92747,P04350,Q16881,O43148,P42566,P49720,P39748,Q15369,Q13547,Q8IXH7,P68371,P25789,P20839,P49721,P84098,P55735,P28482,Q96FJ2,Q9BUF5,P63096,O15145,P13639,O00505,P28072,P78362,Q8WX92,Q9UQB8,P35998,O75116,P05388,O00233,P62244,Q15185,O75446,P25788,P63208,Q8WUX9,Q8WXI9,Q9Y6G9 84
Cellular response to heat stress 0.2145296219145721 0.313601255632673 0.753823905761486 1.0 0.9066881094537628 64 Q9UL15,Q99543,P35244,P55735,Q96B36,P04792,P54652 7
Trna processing 0.2157157301673088 0.3095583029038528 0.7568968690956697 1.0 0.9088023224067902 70 Q9UBP6,O75648,Q9H974,P55735,Q52LJ0,Q9NPF4,Q969Y2,Q9UI30,Q96FX7,Q2VPK5,O60294,O75818,Q9NX74,Q96PZ0,Q7Z4G4,Q9Y3I0,Q96BT7,O15091 18
Interferon gamma signaling 0.309548512529456 0.306290561561987 0.7593834248997544 1.0 0.9107775998459066 14 O75925,Q13555,O15344,Q06124,Q14258,P42224,Q13557,P29372 8
Transcriptional regulation by e2f6 0.3265932577324443 0.303913007264541 0.7611941678621943 1.0 0.9107775998459066 12 O14727,P38398,O75530 3
Regulation of tp53 activity through phosphorylation 0.242745742550171 0.3030579807768606 0.7618456756468803 1.0 0.9107775998459066 34 Q00535,P35244,P35249,Q13526,P54646,P49848,O14757,P40938,P67870,P24941,P35250,Q92547,P38398,P27694,P19784 15
Rrna modification in the mitochondrion 0.3720566371903323 0.3023361018815101 0.7623958599221572 1.0 0.9107775998459066 4 Q9UI43 1
Map2k and mapk activation 0.3040957943273289 0.3012259973249975 0.7632421669278451 1.0 0.9108814116530932 15 Q02750,P28482,P10398,P30086,P12931 5
Esr mediated signaling 0.2242671859124803 0.298721066656655 0.7651528817153272 1.0 0.91162998707229 44 Q99873,P04792,P28482,Q15185,P12931,P63096 6
Resolution of sister chromatid cohesion 0.210912852031503 0.2986741256146981 0.7651887011605327 1.0 0.91162998707229 61 P68371,Q92674,Q16537,P55735,Q96EA4,Q13409,Q96FJ2,Q9BUF5,Q9P258,O60566,O95067,P43034,Q7Z5K2,Q2NKX8,P04350,O43237,Q15691,Q9Y6G9,P30154,O43684,P14635,P06493 22
Deadenylation of mrna 0.2984634627835332 0.2961952956709106 0.7670809412550299 1.0 0.9122770157689636 16 Q9H074 1
Cytokine signaling in immune system 0.1939771986619004 0.2959307039023889 0.7672830023570338 1.0 0.9122770157689636 181 P42574,P49720,P62333,Q15369,P04083,P61081,Q9UL46,O75832,Q13322,P25789,Q06124,P25787,P49721,Q9UII4,P55036,Q06323,Q13325,P35998,P62877,P60953,Q15833,P05388,P55735,Q9UNM6,Q13126,O00233,Q07820,P28482,P78417,P20618,P46109,P41240,P29372,P48556,P40763,Q53EL6,Q99460,P14174,Q02750,Q13526,P07947,P07948,Q13555,Q12846,Q12933,O00170,P25788,P52597,P51452,P63208,Q9H3K6,P28074,Q99436,Q8TBC4,Q99439,Q13616,P30154,O15344,P07355,Q92530,O00231,P06730,O00505,P08670,P28072,P40222 66
Dna damage recognition in gg ner 0.2838447002192776 0.2951022794871024 0.767915748450011 1.0 0.9122770157689636 19 Q92905,Q9UGN5,Q9UBW8,P62877 4
Response to elevated platelet cytosolic ca2 0.2498653447453986 0.2942140763307359 0.7685943250662663 1.0 0.9122770157689636 28 Q15833,P07602,Q12846,Q9NTK5,Q8NBX0,Q9NUQ9,P12814,Q8NBF2,Q9UNF1,Q9BWS9 10
Ire1alpha activates chaperones 0.272838291843731 0.2936408447653428 0.7690323613392493 1.0 0.9122770157689636 21 O14773,Q14999,P51858,Q14203,P43307,P02545,Q06210 7
Raf activation 0.2925576786503611 0.2908179859200187 0.771190528822993 1.0 0.9138326043040386 17 P62140,Q02750,Q13555,P10398,P30154,P12931,Q16537 7
Potassium channels 0.3133167392657097 0.2866669716364527 0.77436732942327 1.0 0.9138326043040386 2 P62879 1
Glucagon type ligand receptors 0.3133167392657097 0.2866669716364527 0.77436732942327 1.0 0.9138326043040386 2 P62879 1
G protein activation 0.3133167392657097 0.2866669716364527 0.77436732942327 1.0 0.9138326043040386 2 P62879 1
Inwardly rectifying k channels 0.3133167392657097 0.2866669716364527 0.77436732942327 1.0 0.9138326043040386 2 P62879 1
Prostacyclin signalling through prostacyclin receptor 0.3133167392657097 0.2866669716364527 0.77436732942327 1.0 0.9138326043040386 2 P62879 1
Transcriptional regulation of granulopoiesis 0.377266970754518 0.2858769510396858 0.7749723677600096 1.0 0.9138326043040386 6 P40763,P24941,P11802 3
Kinesins 0.2850009873822094 0.2795779389405802 0.7798013345691732 1.0 0.9179603444417354 18 P68371,P52732,Q07866,O95239,Q13885,Q9BUF5,Q12756,Q9Y496,Q14807,P04350 10
Association of tric cct with target proteins during biosynthesis 0.2931683883353204 0.2757242394161472 0.7827598766743242 1.0 0.9206493801008307 16 P40763,Q9BUR4,P48643,Q15477 4
Wnt ligand biogenesis and trafficking 0.3675267642445494 0.273245766690437 0.7846643013135419 1.0 0.9206493801008307 5 O75436,Q96QK1 2
Mitotic metaphase and anaphase 0.1807873130478253 0.269982455041547 0.7871737514167125 1.0 0.9206493801008307 139 P49720,P62333,P68371,Q9UL46,O75832,Q92973,P25789,Q92674,P25787,P49721,Q16537,P55036,Q06323,P35998,P55735,Q9UNM6,O00233,Q96EA4,Q13409,Q14674,Q96FJ2,P02545,Q99986,Q9BUF5,P20618,Q13885,Q9P258,O60566,O95067,Q99460,Q9UJX5,P63151,P25788,P43034,Q7Z5K2,Q2NKX8,P04350,Q8WUX9,P28074,Q99436,O43237,Q15691,Q9Y6G9,O43684,P30154,O00231,Q92530,P14635,P06493,P28072 50
Pregnenolone biosynthesis 0.3342670401493939 0.2696688501229258 0.7874150269748061 1.0 0.9206493801008307 3 P22570,P15121 2
Runx3 regulates p14 arf 0.33395580454404 0.2687188904413136 0.7881460138360152 1.0 0.920725098158388 3 Q13951,P42771 2
Unblocking of nmda receptors glutamate binding and activation 0.362173657842799 0.2582882448380529 0.79618445781542 1.0 0.9246444711772356 5 Q13555,Q92796 2
Regulated necrosis 0.2873416143305604 0.2542550657489146 0.7992985116285194 1.0 0.9274815642910276 16 P42574,Q13546,Q8WUX9 3
Interleukin 3 interleukin 5 and gm csf signaling 0.3464548362637432 0.25097249161723 0.8018353771626543 1.0 0.9289016951505994 8 P07947,P46109,Q06124 3
Regulation of tp53 activity through acetylation 0.3105023349043496 0.248927065822735 0.8034171986423262 1.0 0.9291402247060208 12 Q8WXI9,Q92769,Q8TBX8,Q13526 4
Diseases of glycosylation 0.2695695034094996 0.2390767868090376 0.8110460413426743 1.0 0.9324999597236276 19 P36871,P51570,P10619,Q06210,O43505,O95340 6
G protein beta gamma signalling 0.359722156613688 0.2378177395060123 0.8120224592140133 1.0 0.9324999597236276 6 P60953,P61586 2
Dopamine neurotransmitter release cycle 0.3223706227493528 0.2347847341655419 0.8143758169629587 1.0 0.9339978249317916 3 P20336 1
Suppression of phagosomal maturation 0.3481583346037439 0.2304645103948364 0.817730837876679 1.0 0.936534618931476 7 Q9H267,P52294,P31146 3
Heme biosynthesis 0.3515759010322403 0.2301914019560763 0.8179430427281416 1.0 0.936534618931476 5 P50336 1
Insulin receptor recycling 0.3290430020300124 0.2292115714401019 0.8187044792707698 1.0 0.9366304555895728 9 P36543,Q15904,P38606,P21281 4
G2 m dna damage checkpoint 0.2283695815297412 0.2270123469602293 0.8204141413088324 1.0 0.937034994453559 33 P35244,P35249,Q9NXR7,O14757,Q9NWV8,P40938,P35250,Q92547,P38398,P27694,Q04917,P14635,P06493 13
Purine catabolism 0.3271085253415544 0.2238958239750781 0.8228383652367666 1.0 0.9390277628052944 9 P00491,O43598,Q8TCD5,Q96DE0 4
Nucleotide catabolism 0.3157715351079681 0.2198455733566891 0.8259914253768494 1.0 0.9391974397741224 10 P00491,O43598,Q8TCD5,Q96DE0 4
Mrna decay by 3 to 5 exoribonuclease 0.2770342254713093 0.2190733618637176 0.8265929009122135 1.0 0.9391974397741224 16 Q96B26,Q96C86 2
Trans golgi network vesicle budding 0.2248878898367887 0.2190369867777986 0.8266212359790985 1.0 0.9391974397741224 34 Q13492,O00203,O14976,Q92538,P50570,O00161,O95295 7
Stat3 nuclear events downstream of alk signaling 0.3408141197931962 0.216061026051936 0.8289401788683166 1.0 0.9391974397741224 4 Q92769,Q13547 2
Nonsense mediated decay nmd 0.1989851314504652 0.2149657883379609 0.8297939919487263 1.0 0.9391974397741224 86 P62847,P62899,P84098,P05388,P62910,P63151,P42766,P62081,P62244,P62841,Q9Y5S9,P62753,Q8ND04 13
Activation of kainate receptors upon glutamate binding 0.3447460303081319 0.2131776146516849 0.8311884278833288 1.0 0.9391974397741224 5 Q92796 1
Hdr through single strand annealing ssa 0.2790679495837146 0.2130389810691948 0.8312965580154248 1.0 0.9391974397741224 15 P35244,P35249,P40938,P35250,Q92547,P38398,P27694 7
Presynaptic function of kainate receptors 0.3134142545907262 0.2105049722073305 0.8332735713437076 1.0 0.9391974397741224 3 Q01970,P62879 2
L1cam interactions 0.2148487990713722 0.2102362073660832 0.8334833215970376 1.0 0.9391974397741224 39 Q02750,P68371,P50570,P28482,P12931,Q16555,P67870,Q9BUF5,Q92796,P19784,P04350 11
Tp53 regulates transcription of cell cycle genes 0.2815757228446428 0.2093834450871739 0.8341489152523534 1.0 0.9391974397741224 14 Q99873,Q9UIV1,P24941,Q86X55,P14635,P06493 6
Uptake and function of anthrax toxins 0.3127917833800134 0.2088822930179886 0.8345401273825053 1.0 0.9391974397741224 3 Q8WUM4,Q02750 2
Chromatin modifying enzymes 0.1975720708742864 0.2067564848493845 0.8362000418288558 1.0 0.9402998029352958 71 O14929,Q13547,Q99873,Q6IA86,Q86X55,O60678,Q92769,O14744,Q68DK7,O15047,O75530,P15880,Q9UPT9,O95251,Q96EB1,O75446,Q9UBL3,Q8IUF8,Q9BQA1,Q8WXI9,Q15291,P11802 22
Cargo recognition for clathrin mediated endocytosis 0.2241993779705277 0.2042975091625977 0.8381210163273041 1.0 0.9409287120750076 32 Q13492,Q9NVZ3,P42566,Q9Y6I3 4
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.3266964878161462 0.1988681601794472 0.8423658765154178 1.0 0.9441602930610764 8 Q13555,P28482,Q92796 3
Sphingolipid metabolism 0.2364968226561183 0.1898920662259903 0.8493937095917894 1.0 0.9481923317090896 24 P17900,Q13510,Q96G23 3
Fceri mediated ca 2 mobilization 0.3329617928966527 0.1858867512853612 0.8525335720688356 1.0 0.9509292950759732 5 P07948,Q08209,O43865 3
Glycosaminoglycan metabolism 0.2948989747903614 0.1831096017406042 0.8547120220507436 1.0 0.9515329531386808 11 Q9UHD1,O43252,O43505,O95340 4
Chromosome maintenance 0.1918740786180292 0.1825637570547371 0.8551403240218824 1.0 0.9515329531386808 48 P39748,P35249,Q92674,Q9BUR4,Q15054,Q9NPE3,P09884,Q14181,P18858,P35250,P27694,P40937,P49643,Q9Y2S7,P40938,P24941,Q15554,O00743,P35244,Q8WVB6,P49005 21
Interleukin 37 signaling 0.3244370012649513 0.1781095935204408 0.8586369079586085 1.0 0.9532438858682858 4 Q06124 1
Organelle biogenesis and maintenance 0.1886095708166877 0.1768565331269104 0.8596210818673777 1.0 0.9532438858682858 91 P68371,Q13561,Q06546,Q14203,Q92973,Q9Y547,Q86X55,Q9BUR5,Q9NVX0,O75935,O00471,Q92538,Q13409,Q96FJ2,P07437,Q9BUF5,Q96KP1,O60645,P43034,Q9H0F7,P04350,P48643,Q15691,Q9H6D7,Q96CS2,Q9Y496,Q8IW35 27
Fcgr3a mediated il10 synthesis 0.3077467925293115 0.1753946767922179 0.8607695230585415 1.0 0.9532438858682858 9 P07947,P07948,P12931 3
Signal transduction by l1 0.2979199339641759 0.1740130598065043 0.8618551985775857 1.0 0.9532438858682858 10 P19784,P28482 2
Negative regulation of the pi3k akt network 0.268583571727979 0.1727593985810117 0.862840552334909 1.0 0.9532438858682858 14 P12931,P28482,Q8TBX8 3
Rab geranylgeranylation 0.2396288353123363 0.1718197364415922 0.8635792488365015 1.0 0.9532438858682858 21 P61020,Q9BZG1,Q9H0U4,P20339,P20336,Q9ULC3 6
Cytosolic sensors of pathogen associated dna 0.2440081391232873 0.1709266853767691 0.8642814135345307 1.0 0.9532438858682858 20 P35222 1
Cell death signalling via nrage nrif and nade 0.305632751624325 0.1706226683583591 0.8645204725217523 1.0 0.9532438858682858 9 P42575 1
Constitutive signaling by aberrant pi3k in cancer 0.3224906009943721 0.1700700887055663 0.8649550165548701 1.0 0.9532438858682858 7 P12931 1
Sensory processing of sound 0.247089758134003 0.1670281613193525 0.8673478906461765 1.0 0.95452235092479 19 Q14651,P47755,P23634,P20336,P47756 5
M phase 0.1658621919399258 0.1625534172557259 0.8708700666840836 1.0 0.9567109953556466 191 P49720,Q9UL46,O75832,Q13561,Q96GX5,Q14203,P25789,P67870,P25787,P49721,P55036,Q06323,P35998,Q9NVX0,O75935,P55735,O00233,Q96EA4,Q96CW5,Q13409,P28482,Q96FJ2,P02545,Q14674,P07437,Q9BUF5,Q99986,Q9P258,O95067,Q99460,Q9UJX5,P63151,P25788,Q7Z5K2,Q2NKX8,P04350,Q8WUX9,P28074,O43237,Q15691,Q9Y6G9,Q96CS2,Q92530,P19784,P28072 45
G beta gamma signalling through cdc42 0.3135118306351158 0.1556877926402533 0.8762791198942244 1.0 0.9581047683879588 4 P60953,P62879,Q16512 3
Visual phototransduction 0.3138049236522362 0.1526308923058454 0.8786893618903022 1.0 0.9584441184943944 7 Q6NUM9,P30419,P50579,Q8TC12,P53582,P29375 6
Srp dependent cotranslational protein targeting to membrane 0.1807674005301942 0.1489674234533095 0.8815793384184147 1.0 0.9595515105341388 89 P62847,P62899,P84098,P05388,P62910,P62857,P42766,P62081,P08708,P62244,P43307,Q9UHB9,P62841,P62753 14
Translesion synthesis by polh 0.2732328965387514 0.1487158340260164 0.8817778664349909 1.0 0.9595515105341388 12 P35244,P35249,P40938,P35250,P27694,P40937 6
Flt3 signaling 0.3188834840153119 0.1477891655122932 0.8825091601088946 1.0 0.9595811638634872 6 Q13322,Q06124,P41240 3
Rhov gtpase cycle 0.2440823659205023 0.139263152788829 0.8892422059122636 1.0 0.9653831332056152 17 P60953,P16333,P06753,Q8IW35 4
Darpp 32 events 0.278754117547649 0.1336404625922435 0.8936868866383525 1.0 0.9681121538852984 10 Q00535 1
Deadenylation dependent mrna decay 0.1879072995282786 0.1313497728451687 0.8954986197841761 1.0 0.9681121538852984 41 Q9H074,Q96B26,Q96C86,Q9UIV1 4
Erythropoietin activates ras 0.3000427580704411 0.1312456490740975 0.8955809855099006 1.0 0.9681121538852984 4 P46109 1
Synthesis of pips at the plasma membrane 0.2644489931052641 0.1307676973577806 0.8959590772932682 1.0 0.9681121538852984 12 Q13614,Q9BTU6,Q9Y217,Q8TBX8,P20339 5
Sensory perception 0.2081275550030834 0.1278442883144525 0.8982722006025112 1.0 0.9690961602128576 26 Q14651,P50579,P47755,P20336,P23634,Q6IBS0,P47756 7
Hats acetylate histones 0.2123086996818346 0.1174543163648022 0.9065000436543762 1.0 0.975543959442362 23 O14929,Q68DK7,Q6IA86,Q9UPT9,O95251,Q96EB1 6
Golgi associated vesicle biogenesis 0.1973128634543478 0.1155489564898124 0.9080100186386596 1.0 0.975543959442362 29 O14976,Q13492,O00203,O95295 4
Mitotic spindle checkpoint 0.1585659676009456 0.1105242413597131 0.9119936258139034 1.0 0.975543959442362 56 Q9UJX5,O43237,P55735,Q15691,Q9Y6G9,Q96EA4,Q13409,Q96FJ2,Q92674,P43034,P30154,O43684,Q9P258,Q2NKX8,O60566 15
Interleukin 2 family signaling 0.2640979215045681 0.108653883024522 0.9134770212262816 1.0 0.975543959442362 3 P40763 1
Rhou gtpase cycle 0.2343794015705173 0.106968104151705 0.9148142837360302 1.0 0.975543959442362 15 P60953,P16333,P12931 3
Tp53 regulates transcription of dna repair genes 0.1901869825916499 0.1062046927347009 0.9154199477432934 1.0 0.975543959442362 31 P43246,Q15369,Q8IXH7,Q9H3P2,Q8WX92,O14757,P38398,P18074,Q14241 9
Class i peroxisomal membrane protein import 0.281899892848043 0.1014206453409101 0.9192165483614968 1.0 0.9767927004083602 7 Q8TB36,O43808,P40855 3
Signaling by cytosolic fgfr1 fusion mutants 0.2816718882223006 0.101124882286035 0.919451326083068 1.0 0.9767927004083602 7 P40763,Q16630,P11274 3
Eph ephrin mediated repulsion of cells 0.2403996253512266 0.1010104211903558 0.9195421875769004 1.0 0.9767927004083602 13 P07947,P07948,Q15375,P63000,P09497,P12931,Q96CW1,O94973,P09496,P63010,Q00610,P53680 12
Butyrate response factor 1 brf1 binds and destabilizes mrna 0.2422068024177514 0.0945709449430743 0.924655628949576 1.0 0.9812857125565626 12 Q96B26 1
Ripk1 mediated regulated necrosis 0.2479201361860242 0.0871472420748422 0.930554474451456 1.0 0.9839527801774386 10 Q9UNE7,Q16543,Q13546 3
Vitamin b5 pantothenate metabolism 0.2697788483537151 0.0843280858709839 0.9327955826316024 1.0 0.9855684214043382 5 Q9NVE7 1
Atf4 activates genes in response to endoplasmic reticulum stress 0.2212590486012656 0.0771089896433857 0.9385368415939436 1.0 0.9868800032891264 13 Q96B26 1
Formation of tc ner pre incision complex 0.1679842864429494 0.0743650050187869 0.9407199536241106 1.0 0.9868800032891264 29 Q93009,P18074,Q9UBW8 3
Keratan sulfate keratin metabolism 0.2581750233572123 0.0733079975769307 0.9415610276799542 1.0 0.9868800032891264 5 P15586,O43505,P16278,P06865 4
Signaling by erythropoietin 0.2570840149674764 0.0723779603206166 0.9423011239020562 1.0 0.9868800032891264 5 P46109 1
Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.2155176030725822 0.0716145590334469 0.9429086533930644 1.0 0.9868800032891264 13 Q96B26 1
Perk regulates gene expression 0.1998451693991246 0.0687359234586347 0.9451998230277624 1.0 0.9880358050397384 16 Q96B26 1
Gap junction degradation 0.2548286604361436 0.0676442327514462 0.9460688433715494 1.0 0.9880358050397384 6 P50570,P09497,Q96CW1,P09496,Q9UM54 5
Chaperone mediated autophagy 0.2526247018569848 0.0660464809253419 0.947340819786535 1.0 0.9880943493924464 6 Q99497,P08670 2
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.2186212583754779 0.0611834782249509 0.9512130875463896 1.0 0.9910896377840098 10 O43765,Q13190 2
Platelet homeostasis 0.2043517114582139 0.059169780883802 0.95281687881816 1.0 0.9910896377840098 12 Q16537,P30154,P23634,Q06124 4
Mitochondrial trna aminoacylation 0.1677563715654763 0.0561371367569502 0.955232559716571 1.0 0.9910896377840098 19 P49590,P41250,Q9H2U2,Q7L3T8,Q96I59,Q96GW9,Q5JPH6 7
Fceri mediated mapk activation 0.2074251316907923 0.0493093806934183 0.960672743900934 1.0 0.9930848441540086 8 P28482 1
Ras activation upon ca2 influx through nmda receptor 0.2196585261215874 0.049039116387396 0.9608881230550156 1.0 0.9930848441540086 6 Q13555,Q92796 2
Early phase of hiv life cycle 0.2081645372390203 0.0474109807218971 0.9621856775124584 1.0 0.9930848441540086 7 P39748,O75475,P52294,P13010,P18858,P12956 6