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Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
Iron uptake and transport 0.6920537004694793 2.584393876102766 0.0097550320141031 0.9999988934801622 0.4603866725466845 17 P09601,P30519,P36543 3
Formation of atp by chemiosmotic coupling 0.7810250913497476 2.4262546220682597 0.0152555628036545 0.999999999543304 0.4603866725466845 9 P06576,P48047,O75964,P56385 4
Metabolism of porphyrins 0.8313768718148046 2.4143185353658203 0.015764673519268 0.9999999997784716 0.4603866725466845 8 P09601 1
Metabolism of cofactors 0.9279342665064402 2.3289103627201 0.0198638148434144 0.9999999999993548 0.5016650848593327 5 P00374 1
Interleukin 4 and interleukin 13 signaling 0.6920511491238494 2.2193485746575843 0.0264630193478652 1.0 0.5346313891018379 12 P09601 1
Nucleotide binding domain leucine rich repeat containing receptor nlr signaling pathways 0.7089547133805525 2.1506615819434733 0.0315029207995669 1.0 0.5721276525206769 10 P09601 1
Formation of senescence associated heterochromatin foci sahf 0.7059019506142472 2.0632753708243023 0.0390864726986119 1.0 0.5752326632473941 9 P20700,P07305,P16403,P10412,P16402 5
Dna damage telomere stress induced senescence 0.6325508149990917 2.0470114974104923 0.0406569556760387 1.0 0.5752326632473941 14 P06400,P20700,P07305,P16403,P10412,P16402,P62805 7
Heme degradation 0.876433669223204 1.889597589605325 0.058811799794773 1.0 0.654567896403692 4 P09601 1
Rac3 gtpase cycle 0.4753165008496338 1.8789343551294948 0.0602534571568971 1.0 0.6563033177105272 33 O00161,P42167,Q9UQB8,Q5T2T1,Q7L576,P50402,Q6IAA8,O15173,Q12979,Q68EM7,Q8WUY9 11
Insertion of tail anchored proteins into the endoplasmic reticulum membrane 0.6104664455289044 1.8537888880640825 0.0637693688411178 1.0 0.6758586894600292 13 P09601 1
Arachidonic acid metabolism 0.7357189125274507 1.8326670803262823 0.0668520957340086 1.0 0.6822179417336391 7 Q15165,Q8N8N7 2
Sirt1 negatively regulates rrna expression 0.8569623400872417 1.813637848642411 0.0697334994052254 1.0 0.6822179417336391 4 P62805 1
Apoptotic execution phase 0.4853423250149936 1.7991851378942365 0.0719893996035003 1.0 0.6993970142034516 29 Q13464,P20700,Q9Y6E0,Q16625,P07305,P08670,P16403,P10412,P16402,Q15149,P51572 11
Regulation of insulin like growth factor igf transport and uptake by insulin like growth factor binding proteins igfbps 0.5631771265201128 1.765414406016105 0.0774941439897323 1.0 0.7144991210750509 16 Q15293,Q13217,O43852,Q02818 4
Mitochondrial calcium ion transport 0.5625432347848666 1.7615795515261667 0.0781403613470212 1.0 0.7144991210750509 16 Q10713,Q99623,O95202,P45880,Q9UJZ1,Q9Y4W6,Q96TA2,Q9H300,P21796 9
Mitophagy 0.5794577862640774 1.7429474238430458 0.0813427990924995 1.0 0.7294780508359413 14 Q9NS69,Q8N4H5,Q15388 3
Heme signaling 0.682253019788684 1.7332856152951777 0.0830449162135456 1.0 0.7370532300456519 8 P09601 1
Transcriptional regulation of granulopoiesis 0.7125979301810069 1.7292295335647514 0.0837680225713071 1.0 0.7370532300456519 7 P11802,Q03164,P62805 3
Deposition of new cenpa containing nucleosomes at the centromere 0.676528676805223 1.7062549707545764 0.0879606179426208 1.0 0.7580917761635514 8 Q9Y265,Q6IPU0,Q92674,Q71F23,P62805 5
Pink1 prkn mediated mitophagy 0.6215854874492277 1.7025398611752265 0.0886542127370413 1.0 0.7580917761635514 10 Q9NS69,Q8N4H5,Q15388 3
Cellular senescence 0.4544488639669622 1.6983712877581203 0.0894377076637402 1.0 0.7580917761635514 40 P11802,Q9UJX5,P06400,P20700,P07305,P24941,Q9HCE1,P51812,P16403,Q96KQ7,Q16763,P10412,P16402,Q9UJX4,P42771,P62805 16
Apc c cdc20 mediated degradation of cyclin b 0.5949830170447485 1.694497140121929 0.0901708546827158 1.0 0.7580917761635514 12 P14635,Q9UJX5,Q13042,Q12834,Q9UJX3,P06493,Q16763,Q9UJX4 8
Alpha oxidation of phytanate 0.763216651845929 1.6653703455058908 0.0958388919244535 1.0 0.765568240315058 5 Q9BY49 1
Metabolism of folate and pterines 0.6141229099959414 1.663460531406367 0.0962202850721118 1.0 0.765568240315058 10 P00374 1
Fceri mediated ca 2 mobilization 0.741935214483123 1.5767971655883086 0.1148422040597814 1.0 0.8286358464657088 5 P19174,O43865 2
Endosomal vacuolar pathway 0.7884987229295188 1.543197264343094 0.1227829208698849 1.0 0.845713223838164 4 Q9UIQ6 1
Signaling by notch3 0.7000272698220613 1.532156631137381 0.1254837877124777 1.0 0.845713223838164 6 P67809 1
Peroxisomal lipid metabolism 0.5596303490001402 1.497831994287847 0.1341769060092015 1.0 0.8653708936612919 12 Q9BY49 1
Erk mapk targets 0.593896155683383 1.4976340082466484 0.13422836592173 1.0 0.8653708936612919 9 P30153,Q8IV63,P51812,P30154 4
Mapk targets nuclear events mediated by map kinases 0.593896155683383 1.4976340082466484 0.13422836592173 1.0 0.8653708936612919 9 P30153,Q8IV63,P51812,P30154 4
Conversion from apc c cdc20 to apc c cdh1 in late anaphase 0.5797403850668579 1.4821328537800038 0.1383049485365712 1.0 0.8715703738858702 10 Q9UJX5,Q13042,Q12834,Q9UJX3,Q16763,Q9UJX4 6
Dap12 interactions 0.7178555948727143 1.47601204961734 0.1399406575040636 1.0 0.8744963277812612 5 P19174 1
Fcgamma receptor fcgr dependent phagocytosis 0.4499838204351723 1.4723189935202152 0.1409347566304375 1.0 0.8763009978932538 27 Q96JJ3,Q9UQB8,P19174,O15144,O43865 5
Senescence associated secretory phenotype sasp 0.4676351608215109 1.4258212566184296 0.1539199434792926 1.0 0.9153749870949232 21 P11802,Q9UJX5,P24941,P51812,Q96KQ7,Q9UJX4,P42771,P62805 8
Processing of smdt1 0.5559283704238753 1.4161554183159677 0.1567300054370819 1.0 0.9212826790188136 11 Q10713,Q99623,Q9UJZ1,Q9Y4W6,Q96TA2,Q9H300 6
Phase i functionalization of compounds 0.5030884045249263 1.3543993866820037 0.1756089931842313 1.0 0.9740413522875154 15 Q5VT66,P30837,Q16850,P07099 4
Rhog gtpase cycle 0.4037539995136784 1.354259763391485 0.1756535182525276 1.0 0.9740413522875154 36 Q96JJ3,Q86XL3,P42167,Q5T2T1,Q7L576,P50402,Q6IAA8,O15173,O95202,P61604,Q16718,Q8WUY9 12
Parasite infection 0.4651105917476373 1.3525548736504545 0.1761978771584131 1.0 0.9740413522875154 20 Q96JJ3,Q9UQB8,O15144 3
Rho gtpase cycle 0.3511084574483641 1.3455046550799774 0.1784623190250025 1.0 0.9740413522875154 154 Q9UEY8,Q8NBN3,Q9UQB8,Q86XL3,O00161,Q9Y266,P30519,O75116,Q13813,O95202,P06753,O43396,Q14155,Q01082,Q16718,Q68EM7,Q658Y4,P51572,Q5JTV8,Q7L576,Q92974,Q6IAA8,O15173,P62995,Q07021,Q9NSV4,Q96N67,Q9Y6M7,P07910,O14578,Q12979,P61604,Q12792,P12814,Q8WUY9,P38159,P42167,Q96JJ3,P61201,Q12802,P20700,Q99707,P08670,Q9H2G2,P41440,Q5T2T1,Q15642,Q07065,P15924,P50402,Q08378,Q13505,Q8N684,Q96HY6,Q9H8V3,Q13464 56
Nrage signals death through jnk 0.5988817300479131 1.3350661267079191 0.1818547046917129 1.0 0.9740413522875154 8 Q92974,Q12979,Q14155,Q9NY61,Q9H8V3 5
Dag and ip3 signaling 0.5980914714475887 1.331258163790089 0.1831040789631863 1.0 0.9740413522875154 8 P52292,P19174,O43865 3
Aberrant regulation of mitotic exit in cancer due to rb1 defects 0.5387312090788181 1.321997894611988 0.186168851997464 1.0 0.9740413522875154 11 Q9UJX5,P06400,Q13042,Q9UJX3,Q16763,Q9UJX4 6
Carnitine metabolism 0.680695026007785 1.3196319775562937 0.1869579209903484 1.0 0.9740413522875154 5 O43772 1
Rhobtb1 gtpase cycle 0.4594746913299026 1.3148106018640704 0.1885735634686596 1.0 0.9740413522875154 20 P38159,P61201,O75116,P62995,P08670,O43396,P07910,Q8N684,Q13464 9
Signaling by vegf 0.4339838802866509 1.3066400877504485 0.1913349751111268 1.0 0.9740413522875154 25 Q96JJ3,Q9UQB8,O43865,Q13464 4
Fatty acid metabolism 0.4426900732747328 1.3062060899285295 0.1914824823902932 1.0 0.9740413522875154 59 O43772,Q8N8N7,Q15165,Q9BY49,P11310 5
Synaptic adhesion like molecules 0.6451023223524738 1.2916770310443784 0.1964690150384829 1.0 0.9740413522875154 6 O95197 1
Recognition and association of dna glycosylase with site containing an affected purine 0.9004884004884006 1.2900492449271148 0.1970335605825739 1.0 0.9740413522875154 2 P62805 1
Apoptotic cleavage of cellular proteins 0.4682297588475803 1.2722270234763005 0.2032924687142476 1.0 0.9740413522875154 18 Q13464,P20700,Q9Y6E0,Q16625,P08670,Q15149,P51572 7
Regulation of glycolysis by fructose 2 6 bisphosphate metabolism 0.7186927306047655 1.2639582526297946 0.2062450115588254 1.0 0.9740413522875154 4 P30153,P30154,Q14738 3
Cholesterol biosynthesis 0.4637464003163688 1.2434482495904875 0.213702699718536 1.0 0.9740413522875154 18 Q15126,Q15125,Q03426,Q16850,P14324,P48449,O75845 7
Rac2 gtpase cycle 0.3965367512749044 1.240502994932432 0.2147894071340885 1.0 0.9740413522875154 33 P42167,Q86XL3,Q5T2T1,Q7L576,P50402,Q6IAA8,O15173,Q13505,Q12979,Q68EM7,Q8WUY9 11
Glycerophospholipid biosynthesis 0.3957652609111503 1.2342400435814394 0.2171134700545547 1.0 0.9740413522875154 33 Q8NCC3 1
Mitochondrial biogenesis 0.3912722032314032 1.2329678721243598 0.2175877509953629 1.0 0.9740413522875154 34 O75964,P56385,P06576,P48047,Q13505,Q04837,P48735 7
Rhoa gtpase cycle 0.4134751524940883 1.2279069550989938 0.2194818983237767 1.0 0.9740413522875154 47 O00161,Q8NBN3,Q13464,Q92974,P30519,O75116,O15173,Q07021,Q8WUY9,Q9H2G2,O14578,Q12979,Q14155,Q96HY6,Q9H8V3,P41440,P51572 17
Transcriptional activation of mitochondrial biogenesis 0.4888921941886832 1.210975710307004 0.2259047140094536 1.0 0.9784541637746924 14 Q04837,P48735 2
Cristae formation 0.4493268309696324 1.1971351945054465 0.2312538641132651 1.0 0.9844223881686516 19 Q16891,O75964,P56385,P06576,P48047,P24539,Q13505,Q6UXV4 8
Vegfr2 mediated cell proliferation 0.8721001221001223 1.1799385876259918 0.2380246411079456 1.0 0.9844223881686516 2 O43865 1
Mitochondrial protein import 0.3845010013162007 1.1716918249141175 0.2413208063881673 1.0 0.9871573337340528 37 Q9NS69,Q99595,O60830,Q8N4H5 4
Pyrimidine salvage 0.862458819779049 1.1627192309776575 0.2449434364701794 1.0 0.9990550076436766 3 Q9BZX2 1
Runx1 regulates expression of components of tight junctions 0.8601953601953607 1.1340159445768776 0.2567878598371098 1.0 1.0 2 Q16625 1
Toll like receptor cascades 0.4091495787086818 1.108701899170942 0.2675588023565995 1.0 1.0 24 P30153,Q8IV63,P61088,P63208,P50570,Q13546,P05067,Q9BQ95,P14625,P30154,P51812 11
Transcriptional regulation by the ap 2 tfap2 family of transcription factors 0.6020899525269195 1.102770037126106 0.2701270430928226 1.0 1.0 6 P06748,O95619 2
Synthesis of prostaglandins pg and thromboxanes tx 0.6777812093734246 1.100280985301033 0.2712097142933674 1.0 1.0 4 Q8N8N7 1
Clec7a dectin 1 induces nfat activation 0.8513431013431016 1.0999947384361204 0.271334414385691 1.0 1.0 2 O43865 1
Interferon gamma signaling 0.4690889584176152 1.094256184617226 0.2738426360915484 1.0 1.0 14 Q12899,O75925,P29372 3
Diseases of carbohydrate metabolism 0.5137891931199419 1.0827686120610358 0.2789111408104916 1.0 1.0 9 P16278 1
Apoptosis induced dna fragmentation 0.5024239553581951 1.070701104015982 0.2843038462306182 1.0 1.0 10 P10412,P16402,P16403 3
Generation of second messenger molecules 0.6678378851799045 1.060679519591914 0.2888355705166257 1.0 1.0 4 Q8N8S7 1
Erks are inactivated 0.5919793863392416 1.058504941930566 0.2898252989242618 1.0 1.0 6 P30153,Q8IV63,P30154 3
Beta oxidation of octanoyl coa to hexanoyl coa 0.6169762857039498 1.0511875819830878 0.2931724453867645 1.0 1.0 5 P11310 1
Apc cdc20 mediated degradation of nek2a 0.4693332245081207 1.0450677145604708 0.2959916744083242 1.0 1.0 13 Q9UJX5,Q13042,Q12834,Q9UJX3,Q16763,Q9UJX4,O43684 7
Inhibition of the proteolytic activity of apc c required for the onset of anaphase by mitotic spindle checkpoint components 0.4693332245081207 1.0450677145604708 0.2959916744083242 1.0 1.0 13 Q9UJX5,Q13042,Q12834,Q9UJX3,Q16763,Q9UJX4,O43684 7
Ncam signaling for neurite out growth 0.6139645619437858 1.0385630539878938 0.2990079960257992 1.0 1.0 5 Q13813 1
Ptk6 regulates proteins involved in rna processing 0.8351648351648355 1.0381513263219904 0.2991996090705433 1.0 1.0 2 Q07666 1
Hdms demethylate histones 0.5048093039137989 1.0364146887421843 0.3000087205731918 1.0 1.0 9 P62805 1
Er quality control compartment erqc 0.8259541984732792 1.031976725379398 0.3020830208759384 1.0 1.0 3 Q9UKM7,Q9NYU2 2
Pkmts methylate histone lysines 0.4494247614564947 1.0306593040633063 0.302700615185399 1.0 1.0 15 Q96KQ7,Q03164,Q9H7B4,P62805 4
Depolymerisation of the nuclear lamina 0.5337597945010966 1.0215826576503084 0.3069784691853132 1.0 1.0 8 P42167,P20700,P50402,P06493 4
Condensation of prometaphase chromosomes 0.4928127223471956 1.0197854821463297 0.3078302099508319 1.0 1.0 10 O95347,Q9NTJ3,Q15021,P06493 4
Rnd2 gtpase cycle 0.4410498833788824 1.0166473189063492 0.3093212352695014 1.0 1.0 16 P38159,Q07065,Q9Y266,Q08378,Q8WUY9 5
Cyclin d associated events in g1 0.4729575230052378 1.0115324637421823 0.3117616514915093 1.0 1.0 12 P11802,P30153,P06400,P24941,P63208,P42771 6
Regulation of cytoskeletal remodeling and cell spreading by ipp complex components 0.8174579538453344 1.0018024269696535 0.3164390248437017 1.0 1.0 3 Q15404 1
Signaling by alk in cancer 0.3617453478837591 0.991475543673028 0.3214534285274704 1.0 1.0 34 P19174,P10644,P33176,P26038,P63208,P12270,P35579,P06753,Q92734,P18206,P31939,P06748 12
Insulin processing 0.5267287759437238 0.987985021412966 0.3231599839917742 1.0 1.0 8 P33176,Q96KP1,Q9UPT5,Q8TAG9 4
Beta oxidation of decanoyl coa to octanoyl coa coa 0.5746377074168315 0.9828708590662438 0.3256710016814765 1.0 1.0 6 P11310,Q16836 2
Aberrant regulation of mitotic g1 s transition in cancer due to rb1 defects 0.6471171238633031 0.9785605534044326 0.3277971579704439 1.0 1.0 4 P11802,P06400 2
Nuclear events kinase and transcription factor activation 0.4653682777972509 0.9693350728197812 0.3323780354908492 1.0 1.0 12 P30153,Q8IV63,P50570,P30154,P51812 5
Creb1 phosphorylation through nmda receptor mediated activation of ras signaling 0.5225808306246377 0.9682116498448466 0.3329386778871084 1.0 1.0 8 P51812 1
Protein protein interactions at synapses 0.4456049081961447 0.9569144697871736 0.33861042711934 1.0 1.0 14 Q13136,O95197,P41440 3
Ptk6 regulates cell cycle 0.8125763125763131 0.9526929603914518 0.3407456611467494 1.0 1.0 2 P11802 1
Rhob gtpase cycle 0.3830120628271377 0.9398547001112428 0.3472920962680761 1.0 1.0 25 O00161,Q13464,Q92974,Q9H2G2,O14578,Q12979,Q9H8V3,P41440,Q8WUY9 9
Metalloprotease dubs 0.5887405023163579 0.9333601675365044 0.3506340392522769 1.0 1.0 5 O95630,Q9NXR7,O00487 3
Regulation of hmox1 expression and activity 0.3810506676741866 0.9282744442188204 0.3532652269482739 1.0 1.0 49 P28074,P09601,P43686,P28072,P25787,P63208,P28070,O00231,P49721 9
Toll like receptor tlr1 tlr2 cascade 0.4132604281916132 0.9221927794973102 0.356428028711323 1.0 1.0 18 P30153,Q8IV63,P61088,P63208,P05067,Q9BQ95,P30154,P51812 8
Cdc42 gtpase cycle 0.3597047448179435 0.9168512007553932 0.3592206184090056 1.0 1.0 32 O00161,Q9UQB8,Q6IAA8,Q96N67,Q12979,Q14155,Q9H8V3,Q68EM7,Q8WUY9 9
Mismatch repair 0.4463109225583941 0.913903043720258 0.3607677941897174 1.0 1.0 13 Q9Y2S7,Q9UQ84,P18858 3
Meiotic synapsis 0.4445848400927463 0.904149696153847 0.3659160297925499 1.0 1.0 13 P38398,P20700,Q9UQE7,O94901,Q8WXH0,Q9BTC0,Q9UH99,P62805 8
Condensation of prophase chromosomes 0.4619786105765254 0.9033444142669036 0.3663431312792429 1.0 1.0 11 P06400,Q9NTJ3,Q6IBW4,P06493,P62805 5
Tbc rabgaps 0.4442663522943264 0.902351543133019 0.3668701532745664 1.0 1.0 13 Q15907,P60520,P20339,Q15286,P51148,Q4KMP7 6
Nephrin family interactions 0.5308326469742611 0.8999823840508603 0.3681296254562918 1.0 1.0 7 Q9Y5K6,Q13813,P12814,Q01082 4
Role of phospholipids in phagocytosis 0.7838167938931225 0.8836598128580572 0.3768798803031006 1.0 1.0 3 P19174,O43865 2
Synthesis of pa 0.4667832891476865 0.8830650881163127 0.3772011055928683 1.0 1.0 10 Q9NPH0,Q8N2A8 2
Wnt ligand biogenesis and trafficking 0.5513545864184196 0.882191912194094 0.3776730348785071 1.0 1.0 6 Q5T9L3,O60493 2
Rac1 gtpase cycle 0.3630427116182212 0.8812790715256148 0.3781667907718014 1.0 1.0 43 O00161,Q9UQB8,Q5T2T1,P50402,Q6IAA8,Q96N67,O14578,Q12979,Q14155,Q9H8V3,Q68EM7,Q8WUY9 12
Translocation of slc2a4 glut4 to the plasma membrane 0.358237291821422 0.8800803798425682 0.3788157670866403 1.0 1.0 31 O00161,P31946,Q96KP1,P11233,Q8TAG9,Q9UIQ6 6
Formation of the beta catenin tcf transactivating complex 0.4571253644416393 0.8773192711563408 0.380313247812847 1.0 1.0 11 Q04726,Q6P1J9,Q9Y265,P62805 4
Signaling by ntrk3 trkc 0.7805007949371179 0.8721517354891966 0.3831256055964798 1.0 1.0 3 P19174 1
Mitochondrial fatty acid beta oxidation of saturated fatty acids 0.5015731258607066 0.8687595731875308 0.3849786493758764 1.0 1.0 8 P11310,Q16836 2
Signaling by erythropoietin 0.6167809574580239 0.8597830120482458 0.38990866534155 1.0 1.0 4 P19174 1
Toll like receptor 9 tlr9 cascade 0.3969856194800185 0.8589824171409126 0.3903502167266333 1.0 1.0 19 P30153,Q8IV63,P61088,P63208,P05067,Q9BQ95,P30154,P51812 8
Rhof gtpase cycle 0.3999865661597722 0.8395839646077309 0.4011416931732272 1.0 1.0 18 O00161,Q9UEY8,P42167,Q5JTV8,P20700,Q9NSV4,Q9Y6M7,Q8WUY9 8
Assembly of the hiv virion 0.7814407814407822 0.8371323229303753 0.4025181934640427 1.0 1.0 2 Q99816 1
Cytoprotection by hmox1 0.3953845884608694 0.8227723312440073 0.410637473832937 1.0 1.0 68 P09601,P28072,P30519,P25787,P28070,O75880,P13073,O00231,P49721 9
Fcgr3a mediated il10 synthesis 0.5098252151810834 0.8060342348776768 0.4202231095984365 1.0 1.0 7 P19174,O43865 2
Peroxisomal protein import 0.3690880331657988 0.8042248572639028 0.4212671255125455 1.0 1.0 22 O75381,O75874,O14975,Q13011,Q9BY49 5
Synthesis of pyrophosphates in the cytosol 0.7719780219780226 0.8026488641923453 0.4221777167411136 1.0 1.0 2 Q9BW91 1
Irf3 mediated induction of type i ifn 0.5561616030918062 0.7995798543653374 0.4239542633564244 1.0 1.0 5 Q9UJV9 1
Sting mediated induction of host immune responses 0.5561616030918062 0.7995798543653374 0.4239542633564244 1.0 1.0 5 Q9UJV9 1
Synthesis of ip3 and ip4 in the cytosol 0.7591128519418524 0.79865081286322 0.424492915176307 1.0 1.0 3 P19174 1
Arachidonate production from dag 0.7704517704517713 0.7971188442487329 0.4253820130961154 1.0 1.0 2 Q8N2K0 1
Rhobtb gtpase cycle 0.3497839759856526 0.7944131442443924 0.4269549546021594 1.0 1.0 30 P38159,P61201,Q16543,O75116,P62995,Q96T58,P08670,O43396,P08238,P07910,Q8N684,Q12792,P12814,Q8WWQ0,Q13464 15
Insulin receptor recycling 0.4558790920255325 0.7876476522823307 0.4309028331917477 1.0 1.0 9 P36543 1
Budding and maturation of hiv virion 0.5530598529209092 0.7870126328565594 0.4312744710402136 1.0 1.0 5 Q9UN37,Q99816 2
Regulation of innate immune responses to cytosolic dna 0.7652625152625161 0.7783862845847322 0.4363413219230501 1.0 1.0 2 Q9UJV9 1
Myd88 independent tlr4 cascade 0.3838500807983959 0.776645547016067 0.4373679215535428 1.0 1.0 19 P30153,Q8IV63,P61088,P63208,Q13546,P05067,P30154,P51812 8
Ros and rns production in phagocytes 0.4811660727935823 0.7736433299546512 0.4391417409686591 1.0 1.0 8 P36543 1
Vxpx cargo targeting to cilium 0.4808980544497837 0.7724064516066826 0.4398737339341783 1.0 1.0 8 Q96KP1 1
Leishmania infection 0.3354095865067684 0.7720458934632768 0.4400872464052694 1.0 1.0 37 Q96JJ3,P09601,Q9UQB8,P63218,P19174,O15144,P10644,O43865 8
Amyloid fiber formation 0.5227692433319573 0.7606909294513519 0.4468416938287098 1.0 1.0 6 Q92542,P62805 2
E3 ubiquitin ligases ubiquitinate target proteins 0.3902645470166423 0.7456311864927972 0.4558902383891254 1.0 1.0 17 O75381,P61088,P50542,Q6P1J9,O75150 5
Constitutive signaling by ligand responsive egfr cancer variants 0.5869221252983913 0.7453933834868931 0.4560339425844129 1.0 1.0 4 Q16543,P19174 2
Constitutive signaling by egfrviii 0.5869221252983913 0.7453933834868931 0.4560339425844129 1.0 1.0 4 Q16543,P19174 2
Signaling by egfr in cancer 0.5869221252983913 0.7453933834868931 0.4560339425844129 1.0 1.0 4 Q16543,P19174 2
Runx1 regulates transcription of genes involved in differentiation of hscs 0.3426272611931828 0.7379912040967446 0.4605197942072321 1.0 1.0 42 Q03164,P28072,P25787,P28070,O00231,P49721,P62805 7
Recycling pathway of l1 0.375700870728171 0.7264022584068195 0.4675922071213527 1.0 1.0 19 P15311,P51812,P35241 3
Interleukin 17 signaling 0.3968658089237583 0.7228130506447178 0.4697947482780065 1.0 1.0 15 P30153,Q8IV63,P61088,P63208,P30154,P51812 6
Protein localization 0.3908098276798082 0.7227977145357727 0.4698041716684771 1.0 1.0 78 P09601,Q99595,O60830,Q8N4H5,O75874,O14975,Q10713,Q13011,Q9BY49,P06576,Q13505,P40855,P46379,Q9NS69 14
Ercc6 csb and ehmt2 g9a positively regulate rrna expression 0.4191548256110126 0.7178745651386381 0.4728346319963887 1.0 1.0 12 Q86YP4,P62805 2
Pp2a mediated dephosphorylation of key metabolic factors 0.7349618320610625 0.7174250889818983 0.4731118435135566 1.0 1.0 3 P30153,P30154 2
Metabolism of lipids 0.2660044871006104 0.7157536415816453 0.4741434820902119 1.0 1.0 197 O43772,Q8N8N7,Q15125,Q8NCC3,Q9NPH0,Q15165,P16278,Q9BY49,P48449,P11310 10
Cd209 dc sign signaling 0.5769700671960989 0.7080097069696332 0.4789392294672414 1.0 1.0 4 Q13177,P07948,P17612 3
Fc epsilon receptor fceri signaling 0.3581293971965335 0.7052647850883788 0.4806454709829078 1.0 1.0 52 P28074,P43686,P19174,P61088,P28072,P25787,P63208,Q08209,P28070,O43865,O00231,P49721 12
Selective autophagy 0.3337674471096717 0.6989965885030028 0.4845541628375689 1.0 1.0 31 Q9NS69,Q8N4H5,P08670 3
Tcr signaling 0.3465959872612767 0.688599440996482 0.4910753729510966 1.0 1.0 47 P28074,P43686,Q8N8S7,P19174,P61088,P28072,P25787,P63208,P28070,O00231,P49721 11
Transferrin endocytosis and recycling 0.4284410446106655 0.6871470896606083 0.491990042562326 1.0 1.0 10 P36543 1
Ikk complex recruitment mediated by rip1 0.724170973226441 0.6818510525472878 0.4953331386952087 1.0 1.0 3 P61088 1
Ticam1 rip1 mediated ikk complex recruitment 0.724170973226441 0.6818510525472878 0.4953331386952087 1.0 1.0 3 P61088 1
Signaling by flt3 fusion proteins 0.5266238729490748 0.6814930793065043 0.4955595443853071 1.0 1.0 5 Q9UBW7 1
Base excision repair ap site formation 0.5640056534040949 0.659988220823271 0.5092613883949562 1.0 1.0 4 P62805 1
G2 m dna replication checkpoint 0.7169465648854867 0.6583133035180574 0.510336831224969 1.0 1.0 3 P06493,Q99640 2
Cargo trafficking to the periciliary membrane 0.3613909258525893 0.6400971954259225 0.5221094122207062 1.0 1.0 19 A6NIH7,Q10713,Q96KP1,Q8TAG9 4
Cyclin a cdk2 associated events at s phase entry 0.3335893926912465 0.6373319453199608 0.5239086468933838 1.0 1.0 44 P28074,P11802,P43686,P06400,P62195,P24941,P28072,P25787,P63208,P28070,P62191,O00231,P49721 13
Tristetraprolin ttp zfp36 binds and destabilizes mrna 0.3958027946185509 0.6363805784589118 0.5245283964325909 1.0 1.0 13 P31946,Q92973,Q9NPD3 3
Scf skp2 mediated degradation of p27 p21 0.3277513915957972 0.6260226942792733 0.5313000559936767 1.0 1.0 42 P28074,P11802,P43686,P62195,P24941,P28072,P25787,P63208,P28070,P62191,O00231,P49721 12
Nonhomologous end joining nhej 0.3668099424999934 0.6098572578811173 0.5419563682529684 1.0 1.0 17 Q9NXR7,P61088,P12956,Q12888,O96028,P62805 6
Fceri mediated mapk activation 0.4642060596793537 0.6088922898952052 0.5425958350765612 1.0 1.0 7 P07948,P19174 2
Clec7a dectin 1 signaling 0.3357169467975505 0.6081479454920569 0.5430893554300598 1.0 1.0 47 P28074,P43686,P61088,P28072,P25787,P63208,Q08209,P28070,O43865,O00231,P49721 11
Activated notch1 transmits signal to the nucleus 0.7004580152671678 0.6055105718151133 0.5448398024448431 1.0 1.0 3 Q92542,Q96J02 2
Signaling by fgfr3 0.5063909477060649 0.6030939890280714 0.5464461650002486 1.0 1.0 5 P19174 1
Signaling by fgfr4 0.5063909477060649 0.6030939890280714 0.5464461650002486 1.0 1.0 5 P19174 1
Signaling by fgfr1 0.5063909477060649 0.6030939890280714 0.5464461650002486 1.0 1.0 5 P19174 1
Assembly of the orc complex at the origin of replication 0.443181140749224 0.602628988432244 0.5467555314021983 1.0 1.0 8 P62805 1
Signaling by ptk6 0.4107065694179331 0.6000486818616253 0.5484737919859692 1.0 1.0 10 Q96JJ3,P11802,Q07666,Q8IZL8,P23246 5
Tak1 activates nfkb by phosphorylation and activation of ikks complex 0.5046190601335396 0.5963447961167859 0.5509449109771056 1.0 1.0 5 P61088 1
Rap1 signalling 0.697404580152662 0.5958823394461409 0.551253832049843 1.0 1.0 3 P31946,P17612 2
Collagen formation 0.3930254416433008 0.5826106932851568 0.5601554052036497 1.0 1.0 12 Q32P28,Q15149,P13674 3
Dna damage recognition in gg ner 0.3562177300025537 0.5791303776732435 0.5625012040568009 1.0 1.0 18 P54727,P41208 2
Netrin 1 signaling 0.4374128787124788 0.5775750163329028 0.5635510784705411 1.0 1.0 8 P15311,P19174 2
Regulation of runx3 expression and activity 0.3105624032132733 0.5674520238046018 0.5704071131275859 1.0 1.0 38 P28074,P43686,P62195,P28072,P25787,P28070,P62191,O43242,O00231,P49721 10
Fceri mediated nf kb activation 0.3234026711516171 0.5636907239594505 0.5729646313863435 1.0 1.0 44 P28074,P43686,P61088,P28072,P25787,P63208,P28070,O00231,P49721 9
Erythropoietin activates phospholipase c gamma plcg 0.7014652014652024 0.5589027616902318 0.5762280845379615 1.0 1.0 2 P19174 1
Effects of pip2 hydrolysis 0.6827480916030433 0.5503764077872099 0.5820612268298233 1.0 1.0 3 Q8NCG7,Q8N2K0 2
Ketone body metabolism 0.4916996913063397 0.5477747441614821 0.5838465823256798 1.0 1.0 5 P35610 1
Synthesis of ketone bodies 0.4916996913063397 0.5477747441614821 0.5838465823256798 1.0 1.0 5 P35610 1
Notch4 activation and transmission of signal to the nucleus 0.6971916971916983 0.5450659998495527 0.5857081258500911 1.0 1.0 2 Q92542 1
Degradation of axin 0.3073282313755828 0.5445022721815825 0.5860958852474176 1.0 1.0 38 P28074,P43686,P28072,P25787,P28070,O00231,P49721 7
M phase 0.2484415752233281 0.5356231823495134 0.5922190035982728 1.0 1.0 189 Q86XL3,P43686,Q9UJX5,Q8TEM1,P62195,Q12834,Q9Y6G9,Q14997,Q9Y266,Q92621,Q9UJX3,Q9UN37,P30154,Q15021,Q9BTX1,O00231,Q08379,Q29RF7,P17612,P49721,O60763,O75935,P06400,Q15154,P53990,Q92674,P62191,P41208,O43242,Q8N1F7,Q99567,Q15691,P06493,P62805,P42167,P30153,Q14203,Q14204,Q6IPU0,Q8NFH4,P28072,P25787,P20700,Q13561,Q96CW5,O95347,Q16763,Q71F23,Q9UJX4,O43684,P28074,Q14980,P50748,Q14738,P50402,P12270,Q9NTJ3,P28070,P51665,Q6IBW4,Q9H6D7,Q92973,Q96IY1,Q06323 64
Platelet sensitization by ldl 0.4862002805412048 0.5274652207707866 0.5978705622233584 1.0 1.0 5 P30153,P30154 2
Anchoring of the basal body to the plasma membrane 0.3188991289297048 0.522588414693138 0.6012607044090281 1.0 1.0 26 O75935,Q13561,P41208 3
Signaling by notch4 0.317037002828872 0.5192776414305788 0.6035671427268257 1.0 1.0 44 Q13573,P28074,P43686,P28072,P25787,P63208,P28070,O00231,P49721 9
Collagen biosynthesis and modifying enzymes 0.3995733989088507 0.5185169476197249 0.6040976386931314 1.0 1.0 9 Q32P28,P13674 2
Asymmetric localization of pcp proteins 0.3057359352980759 0.517154631007835 0.6050482198666234 1.0 1.0 39 P28074,P43686,P28072,P25787,P28070,O00231,P49721 7
Negative regulation of notch4 signaling 0.3100672652467784 0.5158320252179392 0.6059717330433754 1.0 1.0 41 P28074,P43686,P28072,P25787,P63208,P28070,O00231,P49721 8
Homology directed repair 0.3098865214344689 0.5145893322503454 0.6068400211938574 1.0 1.0 41 P18887,P24941,P61088,P54132,Q12888,Q07864,O96028,Q9UQ84,Q9Y2S7,P35251,P41440,P62805 12
Cdt1 association with the cdc6 orc origin complex 0.3093163962722935 0.5106768133742696 0.6095773791999757 1.0 1.0 41 Q9Y619,P28072,P25787,P28070,O00231,P49721 6
Synthesis of pe 0.6862026862026872 0.5100846321232021 0.6099921711838299 1.0 1.0 2 P35790 1
Signaling by erbb4 0.4391555942783993 0.5066330398530383 0.6124123213208497 1.0 1.0 7 Q92542,P16949,Q96J02 3
Cellular response to hypoxia 0.3102942116341007 0.502357284933155 0.6154162202000535 1.0 1.0 42 Q9Y241,P28072,P25787,P28070,O00231,P49721 6
Processing of dna double strand break ends 0.3131320941232571 0.4981165108479864 0.618401923792284 1.0 1.0 27 Q9UQ84,P62805 2
Degradation of dvl 0.3021469130504066 0.492595693043596 0.6222982918711801 1.0 1.0 39 P28074,P43686,P28072,P25787,P28070,O00231,P49721 7
Late endosomal microautophagy 0.4534211122708136 0.4834405830008703 0.62878293854875 1.0 1.0 6 Q99816,P08670 2
Oncogene induced senescence 0.4320629586056209 0.4787061407412883 0.63214769663209 1.0 1.0 7 P11802,P06400,P42771 3
Defective ripk1 mediated regulated necrosis 0.6752136752136763 0.4760155860690852 0.6340632740247356 1.0 1.0 2 Q13546 1
Diseases of mismatch repair mmr 0.6566375880956961 0.4725282448647168 0.6365497860689864 1.0 1.0 3 P20585 1
Transcriptional regulation by runx3 0.3054218483711622 0.4696447601850568 0.6386088400654828 1.0 1.0 42 Q13573,P28072,P25787,P28070,O00231,P49721 6
Rnd3 gtpase cycle 0.3259783327026703 0.4678434768507852 0.6398965268158852 1.0 1.0 20 P38159,Q07065,P15924,Q8WUY9,Q13464 5
Notch3 intracellular domain regulates transcription 0.6527736207187431 0.4613934908817841 0.6445163206331661 1.0 1.0 3 Q13573 1
Reproduction 0.3127198258952148 0.4596973816312458 0.6457334492054989 1.0 1.0 23 P11802,P38398,P20700,Q14683,P24941,P54132,Q9UQE7,P54652,O94901,O60934,Q8WXH0,Q9BTC0,Q9UH99,P62805 14
Meiosis 0.3127198258952148 0.4596973816312458 0.6457334492054989 1.0 1.0 23 P11802,P38398,P20700,Q14683,P24941,P54132,Q9UQE7,P54652,O94901,O60934,Q8WXH0,Q9BTC0,Q9UH99,P62805 14
Regulation of localization of foxo transcription factors 0.4463444786679735 0.4572123854728941 0.6475183969100295 1.0 1.0 6 P31946,P63104,P27348 3
Ire1alpha activates chaperones 0.3090187636420493 0.4536387317496687 0.6500888714562256 1.0 1.0 25 Q13217,Q9NWM8,P43307 3
Phosphorylation of the apc c 0.3663768084513134 0.4529757489344906 0.650566204272577 1.0 1.0 12 P14635,Q9UJX5,Q13042,Q9UJX3,P06493,Q16763,Q9UJX4 7
Piwi interacting rna pirna biogenesis 0.3842718507968142 0.4508896435460379 0.6520690880777624 1.0 1.0 9 P24928,P30876,P62487,Q8N2A8 4
Hdr through homologous recombination hrr 0.3098342799244015 0.4503115032318645 0.6524858456933351 1.0 1.0 24 Q9UQ84 1
Cytosolic sensors of pathogen associated dna 0.3371735207888445 0.4499878525918476 0.6527191995361055 1.0 1.0 17 O15160,Q13546,Q9UJV9,Q9NVU0,P12956 5
Egfr downregulation 0.4060657796041504 0.4470880105281732 0.6548115153639722 1.0 1.0 8 Q9Y6I3,Q9UBC2,Q14155 3
C type lectin receptors clrs 0.3195243637640377 0.4454165336644978 0.656018766025918 1.0 1.0 51 P28074,P43686,P61088,P28072,P25787,P63208,Q08209,P28070,O43865,O00231,P49721 11
Activation of nmda receptors and postsynaptic events 0.3110180894793072 0.4438877928957592 0.657123710590199 1.0 1.0 22 Q13131,Q14168,P51812,P52292 4
Aurka activation by tpx2 0.3028311611439174 0.4362485701503576 0.6626563918082873 1.0 1.0 27 O75935,Q13561,P41208 3
Regulation of plk1 activity at g2 m transition 0.2944649563203338 0.421249446799522 0.6735729408289282 1.0 1.0 30 O75935,P30153,Q15154,Q14203,Q14204,P63208,P41208,Q15691,Q13561,P06493,Q9H6D7,P17612 12
G2 m dna damage checkpoint 0.284641900742152 0.4210446392022008 0.6737224858091722 1.0 1.0 34 P61088,Q9UQ84,P62805 3
Attachment of gpi anchor to upar 0.4561471077384496 0.4209610873117008 0.6737834968486982 1.0 1.0 5 Q96S52 1
Akt phosphorylates targets in the cytosol 0.4944925471666352 0.4203857067400496 0.6742037079756205 1.0 1.0 4 Q96B36,P31751 2
Degradation of gli1 by the proteasome 0.2963734796593925 0.4113010016164269 0.6808518352318866 1.0 1.0 42 P28074,P43686,P28072,P25787,P63208,P28070,O00231,P49721 8
Metabolism of polyamines 0.2918469422785418 0.4104509746877398 0.6814751596467066 1.0 1.0 40 P28074,P43686,P28072,P25787,P28070,O00231,P49721 7
Hedgehog on state 0.2946496805774155 0.400564168918014 0.6887410305508563 1.0 1.0 42 P28074,P43686,P62195,P28072,P25787,P28070,P62191,O43242,Q6P1J9,O00231,P49721 11
Glutamate neurotransmitter release cycle 0.6309250343823787 0.4005044465067459 0.6887850091058889 1.0 1.0 3 Q13136 1
Runx1 regulates genes involved in megakaryocyte differentiation and platelet function 0.3548863600781328 0.400439306638115 0.6888329781826124 1.0 1.0 12 P62805 1
Nod1 2 signaling pathway 0.4305006948506423 0.4003345155297829 0.6889101491049032 1.0 1.0 6 P61088 1
Formation of incision complex in gg ner 0.3271192798730066 0.3996513014572936 0.6894133652087571 1.0 1.0 17 P61088,P54727,O75925,P41208 4
Cellular response to chemical stress 0.3444797343565319 0.3970425784322283 0.6913360626275198 1.0 1.0 77 P09601,P30519,P28070,O00231,P49721 5
Dna double strand break response 0.3019789206951742 0.394465078528696 0.6932377047102738 1.0 1.0 22 O00213,P52292,P61088,Q12888,O96028,P62805 6
G1 s dna damage checkpoints 0.2936332946210946 0.3942928731258448 0.6933648244182464 1.0 1.0 42 P28074,P43686,P62195,P24941,P28072,P25787,P28070,P62191,O43242,O00231,P49721 11
Activation of the mrna upon binding of the cap binding complex and eifs and subsequent binding to 43s 0.310180316600266 0.3871659119340898 0.6986333843539827 1.0 1.0 51 P62269,P62277,P39019,P46783,P62081,P62847,P62857,P62841,P23588 9
Mastl facilitates mitotic progression 0.4459623694356295 0.3868253211005857 0.6988855302051908 1.0 1.0 5 P06493,P30153,P30154 3
Cross presentation of soluble exogenous antigens endosomes 0.2845642375353481 0.3793649406215567 0.7044168815092986 1.0 1.0 39 P28072,P25787,P28070,O00231,P49721 5
Prevention of phagosomal lysosomal fusion 0.4785076832273554 0.3709021938824593 0.7107103810460556 1.0 1.0 4 Q9H267 1
Regulation of ras by gaps 0.2864426223757589 0.3639322446970018 0.7159086055420345 1.0 1.0 41 P28074,P43686,P28072,P25787,P28070,O00231,P49721 7
Signaling by fgfr1 in disease 0.3521882341197911 0.3617415966494867 0.7175451395086405 1.0 1.0 11 Q9UBW7,P19174,Q16630 3
Regulation of runx2 expression and activity 0.2914698513162219 0.3560585742629097 0.7217966997911203 1.0 1.0 44 P28074,P43686,P28072,P25787,P63208,P28070,O00231,P49721 8
Interaction between l1 and ankyrins 0.6137785509438198 0.3553822705355733 0.7223032292061997 1.0 1.0 3 Q13813 1
Rhod gtpase cycle 0.2880648439538943 0.3534328784150023 0.7237639408371335 1.0 1.0 27 Q9UEY8,P42167,Q5JTV8,P20700,P50402,O15173,Q9NSV4,Q9Y6M7,Q68EM7,Q8WUY9 10
Inositol phosphate metabolism 0.378875159710702 0.3435575364478692 0.731179063829325 1.0 1.0 8 Q96PE3,P19174,Q9BW91 3
Stabilization of p53 0.2828217710697447 0.3427417956739325 0.7317927166942706 1.0 1.0 41 P28074,P43686,P62195,P28072,P25787,P28070,P62191,O43242,O00231,P49721 10
Regulation of pten stability and activity 0.2870483786127784 0.3424831762916726 0.7319873027286472 1.0 1.0 43 P28074,P43686,P28072,P25787,P28070,O00231,P49721 7
Synthesis of diphthamide eef2 0.4678271763731926 0.3393000941965323 0.7343836716936638 1.0 1.0 4 Q9BZG8 1
Dectin 1 mediated noncanonical nf kb signaling 0.2836432084811657 0.335104129262812 0.7375465380730357 1.0 1.0 42 P28074,P43686,P28072,P25787,P63208,P28070,O00231,P49721 8
Ca dependent events 0.3928794803593702 0.3346910266578852 0.7378581711459484 1.0 1.0 7 P52292 1
Ephrin signaling 0.4295428896240226 0.3342010834850533 0.7382278264523712 1.0 1.0 5 Q13177,Q16512,Q14155 3
Global genome nucleotide excision repair gg ner 0.2855090962208852 0.3336968289391127 0.7386083427000711 1.0 1.0 43 P18887,Q9Y265,P54727,O75925,P61088,Q99627,Q07864,P41208,P18858,Q9Y2S7,Q13619,P41440 12
Autophagy 0.2865267636178851 0.3277419846869933 0.7431067559198246 1.0 1.0 44 P61088,Q6IAA8,Q13131,Q8N4H5,Q15388,P08670,Q9NS69 7
Caspase activation via death receptors in the presence of ligand 0.6021374045801402 0.3261959082789182 0.7442761369612951 1.0 1.0 3 Q12933,Q13546 2
Regulation by c flip 0.6021374045801402 0.3261959082789182 0.7442761369612951 1.0 1.0 3 Q12933,Q13546 2
Apc c cdh1 mediated degradation of cdc20 and other apc c cdh1 targeted proteins in late mitosis early g1 0.3009792454737939 0.3237819231995957 0.7461031428020126 1.0 1.0 52 P28074,P43686,Q9UJX5,P06400,P62195,Q12834,P28072,P25787,P28070,P62191,O43242,Q16763,O00231,Q9UJX4,P49721 15
Activation of rac1 0.4623700449606827 0.3236349673289039 0.7462144114367322 1.0 1.0 4 O94813,Q13177 2
Auf1 hnrnp d0 binds and destabilizes mrna 0.2800665117441916 0.3150482270573098 0.7527250370058416 1.0 1.0 42 P28072,P25787,P28070,O00231,P49721 5
Signalling to erks 0.3693016360014668 0.3097039330289999 0.7567861116152659 1.0 1.0 8 P31946 1
Hedgehog ligand biogenesis 0.2751016650435634 0.2996517738315165 0.7644427879268709 1.0 1.0 41 P28074,P43686,P62195,P28072,P25787,P28070,P62191,O00231,Q9UBV2,P49721 10
Tnfr2 non canonical nf kb pathway 0.2792399523680672 0.2990985560443835 0.7648648479941784 1.0 1.0 43 P28074,P43686,P28072,P25787,P63208,P28070,O00231,P49721 8
Oxidative stress induced senescence 0.3188022094027225 0.298422730588779 0.7653805424808093 1.0 1.0 14 P11802,P42771,P62805,Q9HCE1 4
Runx2 regulates bone development 0.4529843806054002 0.2974912941915957 0.7660914535414884 1.0 1.0 4 P06400 1
Signaling by rho gtpases miro gtpases and rhobtb3 0.2642955591601497 0.2950888302283863 0.7679260221984299 1.0 1.0 247 Q9UQB8,P30519,O15173,P62995,Q07021,Q96N67,P61604,Q8WUY9,P38159,Q6IPU0,P08670,P41440,P35080,P15924,P33176,Q08378,Q9H8V3,Q96IY1,Q9UEY8,Q8NBN3,Q86XL3,Q12834,O75116,O95202,O43396,Q14155,Q16718,Q68EM7,P07910,P35580,P62805,P42167,P30153,Q8NFH4,O43684,Q5T2T1,Q15642,P50748,P52306,Q13505,Q8N684,Q13464,O00161,Q9Y6G9,Q9Y266,Q13813,P06753,P30154,Q01082,Q658Y4,P51572,P31946,Q5JTV8,Q7L576,Q92974,Q92674,Q9NSV4,Q9Y6M7,Q15691,O14578,Q12979,Q12792,P12814,Q96JJ3,P59998,P61201,Q12802,Q14204,Q99707,Q07065,Q96HY6,O15144,Q6IAA8,P20700,P35579,Q9H2G2,Q71F23,P50402 78
Cell extracellular matrix interactions 0.3648596853292434 0.2945054536098249 0.7683716967299687 1.0 1.0 8 Q15404 1
Constitutive signaling by akt1 e17k in cancer 0.416139238584188 0.293653220077318 0.7690229039357319 1.0 1.0 5 Q96B36,P31751 2
Sensory processing of sound by outer hair cells of the cochlea 0.3233907660654506 0.2934911869048912 0.7691467348956824 1.0 1.0 13 P26038,P15311,P35241,Q12792 4
Orc1 removal from chromatin 0.2933941711015167 0.292425262665428 0.769961495127298 1.0 1.0 51 P28074,P43686,P62195,Q14997,P28072,P24941,P25787,P63208,Q9Y619,P62191,P28070,O43242,P49736,O00231,P49721,P33993 16
Transcriptional regulation by runx2 0.294907930005956 0.2911815091211935 0.7709125037395341 1.0 1.0 52 P28074,P11802,P43686,P06400,P62195,P28072,P25787,P63208,P28070,P62191,O43242,Q96PK6,O00231,P49721 14
Signaling by the b cell receptor bcr 0.2838085347993166 0.2911303207786185 0.7709516511621182 1.0 1.0 46 P28074,P43686,P28072,Q08209,P25787,P63208,P28070,O43865,O00231,P49721 10
Molybdenum cofactor biosynthesis 0.5866858482603106 0.2893817391213067 0.7722892675660944 1.0 1.0 3 Q9NQX3 1
Met receptor recycling 0.4139932783379139 0.287376085981375 0.7738243699192102 1.0 1.0 5 P62993,P46109,P20338,P62330 4
Inlb mediated entry of listeria monocytogenes into host cell 0.41399327833791 0.2873760859813637 0.7738243699192189 1.0 1.0 5 P62993,Q99961,O14964,P42566 4
Cilium assembly 0.2990049516476307 0.2863903071342132 0.7745791977333294 1.0 1.0 55 O75935,Q96KP1,Q10713,P41208,Q9NQ48,A6NIH7,Q13561,Q8TAG9,Q9H6D7,Q92973 10
Recruitment of mitotic centrosome proteins and complexes 0.272640620131713 0.282574685380686 0.7775028878937007 1.0 1.0 28 O75935,Q13561,P41208 3
Mapk6 mapk4 signaling 0.2877792289443518 0.2820578801509977 0.7778991292325421 1.0 1.0 49 P28074,P43686,Q9NZI8,P62195,Q14997,P28072,P25787,P28070,P62191,O43242,P25685,Q9HCE1,P51665,P06493,O00231,P49721,Q06323,Q16181 18
Rhoj gtpase cycle 0.2774288156262416 0.2810246815417065 0.7786914692187297 1.0 1.0 24 O00161,P42167,Q5T2T1,Q6IAA8,Q9NSV4,Q14155,Q8WUY9 7
Apc c mediated degradation of cell cycle proteins 0.3054846240456464 0.2807177570182504 0.7789268880499363 1.0 1.0 60 P28074,P43686,Q9UJX5,P06400,P62195,Q12834,P24941,P28072,P25787,P63208,P28070,P62191,O43242,P06493,Q16763,O00231,Q9UJX4,P49721 18
Activation of rac1 downstream of nmdars 0.5824143421637158 0.2796076415020626 0.7797785437936806 1.0 1.0 3 Q14155 1
Reactions specific to the complex n glycan synthesis pathway 0.6007326007326022 0.2739113501752239 0.7841527488781408 1.0 1.0 2 Q16706 1
N glycan antennae elongation in the medial trans golgi 0.6007326007326022 0.2739113501752239 0.7841527488781408 1.0 1.0 2 Q16706 1
Synthesis of pg 0.4428624272224961 0.2704771766357889 0.7867931731959916 1.0 1.0 4 Q8N2A8 1
Energy dependent regulation of mtor by lkb1 ampk 0.3726068231331735 0.2683609888950157 0.7884214648295991 1.0 1.0 7 Q13131 1
Interleukin 1 signaling 0.283006025663566 0.2672911975683603 0.7892449636206889 1.0 1.0 48 P28074,P43686,P61088,P28072,P25787,P63208,P28070,O00231,P49721 9
Organelle biogenesis and maintenance 0.326293086442532 0.2609079386780825 0.7941635026535832 1.0 1.0 89 O75935,Q96KP1,O75964,P41208,P56385,A6NIH7,P06576,P48047,Q13561,Q13505,Q8TAG9,Q04837,P48735,Q92973 14
Synthesis of very long chain fatty acyl coas 0.3536857506795532 0.2577804203707035 0.7965763762057088 1.0 1.0 8 Q4G176 1
Cell junction organization 0.2858089620685357 0.2512362520211648 0.8016314581186272 1.0 1.0 19 Q9NVD7,Q15404,Q8N3R9 3
Bmal1 clock npas2 activates circadian gene expression 0.5688549618320472 0.2497803886540621 0.8027571867061654 1.0 1.0 3 Q86X55,P43490 2
Flt3 signaling in disease 0.3814826099789579 0.2438827542446296 0.8073216260808835 1.0 1.0 6 Q9UBW7 1
Apoptosis 0.3223880749098723 0.24054204041248 0.8099100762162541 1.0 1.0 90 P43686,O60313,P07305,O00231,P51572,P31946,P49721,Q16625,P20700,P28072,P25787,Q07157,P08670,Q9NR28,Q15149,P28074,Q9Y6E0,P28070,P16403,P10412,P16402,Q13464 22
Gap filling dna repair synthesis and ligation in gg ner 0.2820754163994713 0.2361306590412057 0.8133312840322402 1.0 1.0 19 P18887,Q07864,P18858,Q9Y2S7,P41440 5
Downstream signaling events of b cell receptor bcr 0.2662974470323322 0.234024000284745 0.81496634642092 1.0 1.0 43 P28074,P43686,P28072,Q08209,P25787,P63208,P28070,O00231,P49721 9
Hur elavl1 binds and stabilizes mrna 0.4273713935371597 0.2316330245126296 0.8168230551493234 1.0 1.0 4 P39687 1
Switching of origins to a post replicative state 0.2948102450027671 0.2294775223904871 0.8184977890656362 1.0 1.0 60 P43686,Q9UJX5,P62195,Q14997,P49736,O00231,P49721,P33993,P62191,O43242,P28072,P25787,P63208,Q16763,Q9UJX4,P28074,P24941,Q9Y619,P28070 19
Rip mediated nfkb activation via zbp1 0.4249344714364852 0.225807842949553 0.8213508768254529 1.0 1.0 4 Q13546 1
Zbp1 dai mediated induction of type i ifns 0.4249344714364852 0.225807842949553 0.8213508768254529 1.0 1.0 4 Q13546 1
Transcriptional regulation by ventx 0.2941070767689718 0.2249942732844445 0.8219837293155359 1.0 1.0 15 Q9UJX5,Q13042,Q9UJX3,Q96KQ7,Q16763,Q9UJX4,P42771,Q9HCE1 8
Phospholipid metabolism 0.2750516302501289 0.2208363620683103 0.8252198496350052 1.0 1.0 49 Q8NCC3 1
Uch proteinases 0.2728495395732026 0.2192366853546091 0.826465679747683 1.0 1.0 48 Q9Y4E8,P28072,P25787,P28070,O00231,P49721 6
Suppression of phagosomal maturation 0.3540246557163233 0.2133768394483524 0.8310330439759184 1.0 1.0 7 Q9H267,P20339 2
Dna double strand break repair 0.2851883991201497 0.2132786269087332 0.8311096432950438 1.0 1.0 56 O00213,P18887,P52292,P24941,P61088,P12956,Q12888,Q07864,O96028,Q9UQ84,Q9Y2S7,P41440,P62805 13
Gamma carboxylation hypusine formation and arylsulfatase activation 0.3058498134414307 0.2065635167393635 0.8363507551369276 1.0 1.0 12 Q9BZG8,O60725,Q9HA64,P38435 4
Interleukin 1 family signaling 0.2734598562017193 0.2059980578504896 0.8367924283833448 1.0 1.0 50 P28074,P43686,P61088,P28072,P25787,P63208,P28070,O00231,P49721 9
Activation of ppargc1a pgc 1alpha by phosphorylation 0.5689865689865705 0.2057312307447805 0.8370008617536158 1.0 1.0 2 P54619 1
Alk mutants bind tkis 0.3499909158973354 0.2022319412081425 0.8397354035076159 1.0 1.0 7 P10644 1
Programmed cell death 0.31435656508376 0.2005569403398806 0.8410450305005517 1.0 1.0 99 P43686,O60313,P07305,O00231,P51572,P31946,P49721,Q16625,P20700,P28072,P25787,Q07157,P08670,Q9NR28,P41440,Q15149,P28074,Q9Y6E0,P28070,P16403,P10412,P16402,Q13464 23
Meiotic recombination 0.3039119674420368 0.2000819061690811 0.8414165240285127 1.0 1.0 12 P11802,P24941,P62805 3
Signaling by erbb2 ecd mutants 0.3794490415862985 0.1952149067096011 0.8452247096940033 1.0 1.0 5 Q16543,P19174 2
Signaling by erbb2 in cancer 0.3794490415862985 0.1952149067096011 0.8452247096940033 1.0 1.0 5 Q16543,P19174 2
Tnfr1 induced proapoptotic signaling 0.5413100995903688 0.1950320689492976 0.8453678422637778 1.0 1.0 3 Q13546 1
Chk1 chk2 cds1 mediated inactivation of cyclin b cdk1 complex 0.3105274183038756 0.1905844590150333 0.8488511669207419 1.0 1.0 10 P31946,P63104,P14635,P06493 4
Rhobtb2 gtpase cycle 0.2655659384674473 0.1891699360953525 0.849959629738783 1.0 1.0 20 P38159,Q16543,P62995,O43396,P08238,P07910,Q12792,P12814,Q8WWQ0 9
Defective cftr causes cystic fibrosis 0.2555380436306933 0.1868292544881276 0.851794508988402 1.0 1.0 43 P28074,P43686,P62195,P28072,P25787,P28070,P62191,O00231,Q9UBV2,P49721 10
Tysnd1 cleaves peroxisomal proteins 0.372643707345472 0.1791534758686456 0.8578171934990144 1.0 1.0 5 P09110,Q15067 2
Hedgehog off state 0.266834275896841 0.1789117896633976 0.8580069653403344 1.0 1.0 50 P28074,P43686,P10644,P62195,Q8NCM8,P28072,P25787,P63208,P28070,P62191,O43242,O00231,P49721 13
The role of gtse1 in g2 m progression after g2 checkpoint 0.264818224161243 0.1780154258670648 0.8587108611436558 1.0 1.0 49 Q9NYZ3,P28072,P25787,P28070,O00231,P49721 6
Rna polymerase i transcription 0.2527298892590863 0.1737319829758203 0.8620761009539646 1.0 1.0 22 O15160,Q86YP4,P62805 3
Phosphorylation of emi1 0.3979772251668525 0.1667908191317238 0.8675346427679616 1.0 1.0 4 P06493,Q12834 2
Regulation of mrna stability by proteins that bind au rich elements 0.2834877730688608 0.1667423066720899 0.8675728155889002 1.0 1.0 63 P31946,P28074,P43686,P62195,P28072,Q5RKV6,P25787,P28070,P62191,P39687,Q92973,O00231,Q9NPD3,P49721 14
Ctla4 inhibitory signaling 0.3362649194610266 0.1665271241655853 0.8677421391787157 1.0 1.0 7 P30153,P07948,P30154,Q14738 4
Sumoylation of transcription factors 0.3517613267335193 0.1664421570384343 0.867809000090731 1.0 1.0 6 O75925,Q12888 2
Degradation of beta catenin by the destruction complex 0.2604861647279933 0.1616491825915398 0.8715821244994313 1.0 1.0 49 P28074,P43686,P30153,P62195,Q14738,Q14997,P28072,P25787,P63208,P28070,P62191,O43242,P51665,P30154,Q04726,O00231,P49721 17
Recruitment of numa to mitotic centrosomes 0.2376357994178156 0.1607890833127692 0.8722595236157973 1.0 1.0 32 O75935,Q13561,P41208 3
Sensory processing of sound 0.2624757594665907 0.1529242219529206 0.8784580342169392 1.0 1.0 18 P15311,P35241,P20020,P26038,Q13813,P35579,Q12792 7
Abc transporter disorders 0.2454474002946392 0.1416690475660081 0.8873414247658522 1.0 1.0 44 P28072,P25787,P28070,O00231,P49721 5
Cytokine signaling in immune system 0.2000668527207132 0.141593708432226 0.8874009368048543 1.0 1.0 178 P09601,P43686,P61221,Q53EL6,Q9BTX1,O00231,P49721,P19174,Q8N1F7,Q12899,Q8IV63,P20700,P29372,P61088,P28072,P26038,P25787,P11233,P63208,P08670,P51812,P28074,P52292,O75925,Q13126,P28070,P40222 27
Antigen processing cross presentation 0.2615306963222351 0.1414328277284393 0.887528022136536 1.0 1.0 53 O00161,P28072,P25787,P28070,O00231,Q9UIQ6,P49721 7
Hcmv late events 0.2280011135809755 0.1398187908604578 0.8888031661755917 1.0 1.0 34 Q8TEM1,Q8NFH4,P12270,Q8N1F7,Q9UN37,Q99567,Q99816,Q9HD42,Q9BTX1,P62805 10
Beta oxidation of very long chain fatty acids 0.3837731129409396 0.1398169129733131 0.8888046499385749 1.0 1.0 4 P09110 1
Rna polymerase iii transcription initiation from type 3 promoter 0.3544208545852604 0.1397497162404754 0.8888577439205227 1.0 1.0 5 O15160,Q9NVU0 2
Rna polymerase iii chain elongation 0.3544208545852604 0.1397497162404754 0.8888577439205227 1.0 1.0 5 O15160,Q9NVU0 2
Endosomal sorting complex required for transport escrt 0.339841000727035 0.1395740024002167 0.8889965826018018 1.0 1.0 6 Q9UN37,Q99816 2
Creb1 phosphorylation through the activation of adenylate cyclase 0.5075172294687353 0.1390106048802537 0.8894417689324035 1.0 1.0 3 P10644 1
Pka mediated phosphorylation of creb 0.5075172294687353 0.1390106048802537 0.8894417689324035 1.0 1.0 3 P10644 1
Pka activation in glucagon signalling 0.5075172294687353 0.1390106048802537 0.8894417689324035 1.0 1.0 3 P10644 1
Rna polymerase iii transcription termination 0.3394481196393143 0.1387307303164804 0.889662933622769 1.0 1.0 6 O15160 1
Synthesis of pc 0.3392748687194751 0.1383597306616817 0.8899561211366489 1.0 1.0 6 Q9NQZ5 1
Cyclin a b1 b2 associated events during g2 m transition 0.292045601132019 0.1375299957951165 0.8906118847893152 1.0 1.0 10 P30153,P24941,P30154,P06493,Q99640 5
Trna modification in the mitochondrion 0.3225051922243112 0.1342850974891256 0.8931771369886214 1.0 1.0 7 Q969Y2,O15091 2
Heme biosynthesis 0.3796579108124557 0.1325435990444217 0.8945543401483877 1.0 1.0 4 P08397,P06132,P22830 3
Polymerase switching on the c strand of the telomere 0.2638800621892463 0.1285101518372352 0.8977452648348558 1.0 1.0 15 Q8WVB6,P41440 2
Cell cycle mitotic 0.239780111871543 0.1234193519537056 0.9017750335822976 1.0 1.0 250 Q86XL3,P43686,Q9UJX5,Q8TEM1,P62195,Q12834,Q9Y6G9,Q14997,Q9Y248,Q9Y266,Q9UN37,P00374,P49736,P30154,Q9BTX1,Q9Y2S7,O00231,P35251,Q29RF7,Q08379,Q7L590,P49721,P33993,O60763,O75935,P06400,P11802,Q15154,P53990,Q92674,Q07864,P41208,O43242,P62191,Q8N1F7,Q99567,Q9BRT9,P06493,P42771,P62805,P42167,P30153,P20700,Q6IPU0,Q8NFH4,P28072,P25787,P63208,Q13561,Q96CW5,O95347,Q16763,P41440,Q9UJX4,O43684,Q71F23,P28074,Q9NYZ3,P50748,P24941,Q9Y619,P12270,Q9NTJ3,P50402,P28070,P18858,Q6IBW4,Q9H6D7,Q92973,Q96IY1,Q99640 71
Signaling by insulin receptor 0.2612841008939957 0.1215827782609277 0.9032294532477054 1.0 1.0 15 P36543 1
Disassembly of the destruction complex and recruitment of axin to the membrane 0.3443461476608569 0.1202626640679494 0.904275079161046 1.0 1.0 5 P30153,P30154 2
Beta catenin phosphorylation cascade 0.3443461476608569 0.1202626640679494 0.904275079161046 1.0 1.0 5 P30153,P30154 2
Signaling by ctnnb1 phospho site mutants 0.3443461476608569 0.1202626640679494 0.904275079161046 1.0 1.0 5 P30153,P30154 2
Biological oxidations 0.2383480893948753 0.119002584868668 0.9052733079068572 1.0 1.0 44 P48637,P30837,Q16850,P07099,Q5VT66 5
Transport of inorganic cations anions and amino acids oligopeptides 0.2811366058860355 0.1182162160671985 0.905896341489751 1.0 1.0 11 Q70HW3,Q9Y6M7,P08195 3
Interferon alpha beta signaling 0.2867241921335648 0.1168162212903081 0.907005689030986 1.0 1.0 9 P61221 1
Diseases of mitotic cell cycle 0.2554274965269074 0.1141891996313034 0.9090878133526292 1.0 1.0 16 P11802,Q9UJX5,P06400,Q13042,P24941,Q9UJX3,Q16763,Q9UJX4 8
Signaling by braf and raf1 fusions 0.2322569016741765 0.1115772727169368 0.9111585932213953 1.0 1.0 23 P51114,Q9NRY5 2
Free fatty acids regulate insulin secretion 0.5103785103785121 0.1114404955761647 0.911267049206406 1.0 1.0 2 O95573 1
Unfolded protein response upr 0.2337051178942239 0.1110791971383728 0.911553544921376 1.0 1.0 43 Q13217,O95070,Q5RKV6,Q8N6T3,Q9NWM8,Q9NPD3,P43307 7
Oas antiviral response 0.4831672403221883 0.1063273844407046 0.9153226050994494 1.0 1.0 3 P61221 1
Butyrate response factor 1 brf1 binds and destabilizes mrna 0.2708514328085505 0.1053278658694104 0.9161156521858482 1.0 1.0 12 P31946,Q9NPD3 2
Rhoq gtpase cycle 0.2285984905791947 0.1051814864711145 0.916231800883051 1.0 1.0 25 O00161,Q15642,Q5T2T1,Q6IAA8,Q9NSV4,Q14155,Q68EM7,Q8WUY9 8
Golgi cisternae pericentriolar stack reorganization 0.2783406227534418 0.1037764112910822 0.9173467864394074 1.0 1.0 10 O60763,P14635,Q08379,P06493 4
Runx1 interacts with co factors whose precise effect on runx1 targets is not known 0.2510729613733895 0.1033618892918737 0.917675758032245 1.0 1.0 16 Q92922,Q99496,Q86U86,Q96GM5,Q9HC52,Q8TAQ2,Q969G3,Q12824,P51532,P68400,P67870,Q68CP9,O14497,P19784,Q14781 15
G2 m checkpoints 0.2823672868765802 0.1033335036777734 0.9176982858467329 1.0 1.0 86 Q9NXR7,P43686,P62195,Q14997,O96028,Q9UQ84,P49736,O00231,Q7L590,P49721,P33993,P31946,P62191,O43242,P06493,P62805,P61088,P28072,P25787,Q12888,P28074,Q9NYZ3,P24941,Q9Y619,P54132,P28070,Q99640 27
Cell cycle checkpoints 0.247733176901805 0.1003521783673525 0.9200647341748768 1.0 1.0 143 Q9NXR7,P43686,Q9UJX5,Q9Y6G9,P62195,Q12834,Q9Y266,Q14997,O96028,Q9UQ84,P49736,P30154,O00231,Q7L590,P49721,P33993,P31946,Q92674,P62191,O43242,P06493,P42771,P62805,P30153,Q6IPU0,P61088,Q8NFH4,P28072,P25787,Q12888,Q16763,Q71F23,Q9UJX4,O43684,P28074,Q9NYZ3,P50748,P24941,Q9Y619,P54132,P28070,Q96IY1,Q99640 43
Signaling by hedgehog 0.2520390404856507 0.1003067314353315 0.9201008135351252 1.0 1.0 56 P28074,P43686,P10644,P62195,Q8NCM8,P28072,P25787,P63208,P28070,P62191,O43242,Q6P1J9,O00231,Q9UBV2,P49721 15
Signaling by notch 0.2588732883563592 0.0998350776885091 0.9204752591884044 1.0 1.0 61 P43686,P62195,Q15398,O00231,P49721,Q13573,P67809,P62191,O43242,Q9UBV2,P62805,P28072,P25787,Q92542,P63208,Q96J02,P28074,P28070,Q9HCE1 19
Signaling by egfr 0.2684508534157025 0.0996430872706534 0.9206276853309155 1.0 1.0 12 Q9Y6I3,Q9UBC2,P19174,Q14155 4
Tcf dependent signaling in response to wnt 0.2610057369067016 0.0987759093503489 0.921316196488384 1.0 1.0 63 P43686,Q9Y265,P62195,Q14997,P30154,Q04726,O00231,P49721,P62191,O43242,P62805,P30153,P28072,P25787,Q6P1J9,Q9UBL3,P28074,Q14738,P28070,Q9HCK8,P51665 21
Initiation of nuclear envelope ne reformation 0.2445883680649992 0.0953501239850727 0.9240367307956678 1.0 1.0 17 P42167,Q86XL3,P20700,P50402,P06493 5
Class i peroxisomal membrane protein import 0.2893806036059159 0.0939076189856349 0.9251825415112258 1.0 1.0 8 O75381,P40855 2
Protein ubiquitination 0.2237808509674029 0.0930468437214118 0.9258663467056304 1.0 1.0 25 O75381,P61088,P50542,Q92541,Q16763,Q6P1J9,O75150 7
Chromosome maintenance 0.2376628281796268 0.0925562706722519 0.9262560855047016 1.0 1.0 49 Q9Y265,Q6IPU0,Q92674,P24941,Q8WVB6,P54132,Q9NPE3,P18858,P06748,Q71F23,Q9Y2S7,P35251,P41440,Q9Y230,P62805 15
Rab regulation of trafficking 0.217060058235198 0.0923670126870004 0.9264064474195804 1.0 1.0 31 P31150,Q15907,P60520,P20339,Q14C86,Q15286,P51148,Q4KMP7 8
E2f enabled inhibition of pre replication complex formation 0.3255877500492167 0.088374013241413 0.9295794148973632 1.0 1.0 5 P06493,Q9Y619 2
Signaling by notch1 0.2712396369586238 0.088186953455238 0.9297280865501868 1.0 1.0 10 Q13573,P63208,Q92542,Q96J02 4
Tp53 regulates metabolic genes 0.2104158649400765 0.0878400712138643 0.9300037886167009 1.0 1.0 34 P31946,Q13131,P13073,O75880 4
Regulation of tp53 expression and degradation 0.2668209923881712 0.0847444893734341 0.9324645257540274 1.0 1.0 11 P06493,P30153,P42771,P24941 4
Signaling by interleukins 0.2751086598454433 0.08471497797391 0.9324879880732442 1.0 1.0 107 P09601,Q8IV63,P61088,P28072,P26038,Q13126,P28070,Q53EL6,P08670,P25787,P11233,O00231,P51812,P49721 14
Cell cell communication 0.2166644851093845 0.0825870205214829 0.9341799221391468 1.0 1.0 28 Q14315,Q13813,Q9Y5K6,Q01082,Q9NVD7,Q15404,Q8N3R9,P12814,Q15149 9
Response to elevated platelet cytosolic ca2 0.2115186014988168 0.0825615488442269 0.9342001764272664 1.0 1.0 32 Q8NBX0,O94919,O43852 3
Aspartate and asparagine metabolism 0.3217389865332226 0.0825332859835257 0.9342226502277844 1.0 1.0 5 Q9UJS0,P08243 2
Nuclear events stimulated by alk signaling in cancer 0.2651633564769187 0.0812265335574952 0.9352617985035596 1.0 1.0 11 P33176,P63208 2
Rnd1 gtpase cycle 0.2403417498854045 0.0793612577939157 0.9367452832123216 1.0 1.0 16 P38159,P15924,Q8WUY9 3
Transcriptional regulation by runx1 0.2614287051483295 0.0787082965343266 0.9372646462755548 1.0 1.0 72 P28074,P62805,P43686,Q03164,Q16625,P28072,P25787,Q07157,P28070,Q969G3,O00231,P49721 12
Cell cycle 0.2474055395835224 0.078407244441799 0.9375041110428466 1.0 1.0 297 P43686,P62195,Q9UN37,P00374,Q9UQ84,O00231,Q29RF7,P49721,O75935,P06400,P53990,Q07864,P41208,Q99567,Q9BRT9,Q6IPU0,Q12888,Q96CW5,P41440,Q9UJX4,Q9NYZ3,P24941,P12270,P28070,Q6IBW4,Q92973,Q96IY1,Q86XL3,Q9UJX5,Q9Y265,Q8TEM1,Q12834,O96028,P49736,P35251,P62191,O43242,P06493,P06748,P42771,P62805,P42167,P30153,P61088,Q8NFH4,Q13561,O95347,Q16763,O43684,P50748,Q9Y619,P54132,Q9H6D7,Q99640,Q9NXR7,Q9Y6G9,Q9Y266,Q14997,Q9Y248,P24928,Q8WVB6,P30154,Q9BTX1,Q08379,P33993,P31946,Q92674,Q9UH99,P28072,P25787,P28074,Q9NTJ3,Q9NPE3,P18858,Q9Y230,Q9Y2S7,Q7L590,O60763,P11802,Q15154,Q8N1F7,P20700,P63208,Q71F23,P50402,Q8WXH0 86
Peptide hormone metabolism 0.2462902370991365 0.0745748151770565 0.9405530128880756 1.0 1.0 14 P33176,Q8TAG9,Q96KP1,P67812 4
Neddylation 0.2653299277535222 0.0735802377290889 0.941344396513388 1.0 1.0 81 P28074,P43686,O94888,P28072,Q99627,P25787,P63208,P28070,Q13619,Q9BTE7,O00231,Q96GG9,O60826,P49721 14
Rhoh gtpase cycle 0.2161087894616904 0.07273666890135 0.9420156682547528 1.0 1.0 22 Q6IAA8,O75116,Q99707,Q9Y6M7,Q658Y4,Q8WWQ0,Q13464 7
Cytosolic iron sulfur cluster assembly 0.2900109335002534 0.0726423643281318 0.9420907138937944 1.0 1.0 7 O76071,O75027,Q9Y5Y2,Q6FI81,P28340 5
Signaling by ntrks 0.2058410008578514 0.0673056240862875 0.9463383996705286 1.0 1.0 31 P31946,P30153,Q8IV63,P19174,Q8WX92,P50570,P11233,P51812 8
Miscellaneous transport and binding events 0.2859891832270193 0.0664214161985266 0.9470423201904196 1.0 1.0 7 Q9UEY8,Q8IWT6,Q8N4V1 3
Tfap2a acts as a transcriptional repressor during retinoic acid induced cell differentiation 0.4425100961395051 0.065396207978358 0.9478585432137828 1.0 1.0 3 P06748 1
Ub specific processing proteases 0.2586997783654197 0.0639590858848476 0.949002804804818 1.0 1.0 80 P43686,Q9Y265,P62195,Q12834,Q9Y4E8,Q14997,Q96K76,Q15388,O00231,P49721,P62191,O43242,P21796,Q969V5,P28072,P54578,P25787,O60493,Q14318,P28074,Q13546,P28070,P45880 23
N glycan trimming in the er and calnexin calreticulin cycle 0.2338323816291373 0.0615306021216576 0.95093664360234 1.0 1.0 15 P54727,Q9UBV2,Q9UKM7,Q9NYU2 4
Activation of bad and translocation to mitochondria 0.2699409902121148 0.0613697322029791 0.9510647571119336 1.0 1.0 8 P31946,P63104,P27348 3
Rhov gtpase cycle 0.2276371754405587 0.0608149378518158 0.9515065936562817 1.0 1.0 17 Q13813,P06753,O43396,Q14155,Q8WUY9 5
G0 and early g1 0.3054633373004842 0.0604139879772461 0.9518259182122976 1.0 1.0 5 P24941 1
Pcp ce pathway 0.2242720685335348 0.0592296390524794 0.9527692025260824 1.0 1.0 51 P28072,P25787,P28070,O00231,P49721 5
Cellular responses to stimuli 0.2374129072858734 0.0573952707535626 0.9542303301859903 1.0 1.0 327 P09601,P07305,P39019,P30519,P61353,P36543,O75880,Q96EB6,Q9BTX1,O00231,P43307,P49721,P62899,Q13217,O75935,Q9Y241,P62081,P21281,P62841,P62805,P62269,P62277,P28072,P25787,P62847,Q13561,Q9NWM8,P42766,P51812,P62750,P28074,P61254,P28070,P46783,P48723,Q13451,P62857,P16403,P13073,P10412,P16402 41
Mitotic g1 phase and g1 s transition 0.2525040547634813 0.057129678817676 0.9544418947468474 1.0 1.0 78 P43686,P62195,P00374,P49736,O00231,Q7L590,P49721,P11802,P06400,Q07864,P62191,O43242,P06493,P42771,P28072,P25787,P63208,P28074,P24941,Q9Y619,P28070 21
Innate immune system 0.2112124608440055 0.0568025498404994 0.9547024827407288 1.0 1.0 277 O00161,P09601,Q9UQB8,P43686,P42785,P62195,O15144,Q86VP1,P30519,P12956,Q13442,P36543,O00231,P51148,P49721,Q13217,P01889,P11216,P04080,P18669,P19174,Q5T9A4,Q6IAA8,Q9UJV9,P16278,P21281,O43865,Q96JJ3,O15160,Q8IV63,O00264,P61088,P28072,P25787,O75874,P63208,O14975,Q8WVQ1,P35579,Q9H7Z7,P42025,P51812,P28074,Q07065,Q08209,P28070,Q9BQ95,Q13464 48
Mrna decay by 3 to 5 exoribonuclease 0.2309017369270603 0.0565027888269946 0.95494127391369 1.0 1.0 15 Q5RKV6,Q9NPD3,Q15477,Q9Y450 4
Rna polymerase i promoter escape 0.2415302137656849 0.0558501076096929 0.9554612171066486 1.0 1.0 13 P62805 1
Dna damage reversal 0.3013638604169349 0.0554849098484012 0.9557521516266474 1.0 1.0 5 Q8N3C0,Q6P6C2 2
Fgfr1 mutant receptor activation 0.2519292610946815 0.0522649615716173 0.9583175717566266 1.0 1.0 10 Q9UBW7,Q16630 2
Response of mtb to phagocytosis 0.2390945374118803 0.0517425481176424 0.9587338341324454 1.0 1.0 13 Q9H267,P23246,P20339 3
Infection with mycobacterium tuberculosis 0.2390945374118803 0.0517425481176424 0.9587338341324454 1.0 1.0 13 Q9H267,P23246,P20339 3
Metabolism of steroids 0.2141207226820635 0.0488725222099068 0.9610208867860628 1.0 1.0 49 O00767,Q15125,O75845,P38435,O14975,Q16850,O95772,P14324,Q53GQ0,P48449 10
Formation of tc ner pre incision complex 0.1998669895783375 0.0471008387460473 0.9624328588585896 1.0 1.0 25 P61201,Q9UNP9,P24928,Q99627,P62487,Q9UNS2,P23193,P19447,Q13619,P30876,P18074,Q93009 12
Abc family proteins mediated transport 0.2185645215715848 0.046916854438852 0.9625794949864028 1.0 1.0 53 P28074,P43686,P62195,P28072,P25787,P28070,P40855,O00231,Q9UBV2,P49721 10
Post translational modification synthesis of gpi anchored proteins 0.2840132816305697 0.0469141682294711 0.9625816359139374 1.0 1.0 6 Q96S52 1
Cd28 dependent pi3k akt signaling 0.4365079365079384 0.0468632381594788 0.9626222275845072 1.0 1.0 2 P31751 1
Mitotic metaphase and anaphase 0.2079648628479315 0.0459315836863277 0.9633647805932544 1.0 1.0 135 Q86XL3,P43686,Q9UJX5,Q9Y6G9,P62195,Q12834,Q14997,Q9Y266,Q9UN37,Q9BTX1,O00231,Q29RF7,P49721,P53990,Q92674,P62191,Q8N1F7,O43242,P06493,P42167,P30153,P20700,Q6IPU0,Q8NFH4,P28072,P25787,Q16763,Q71F23,Q9UJX4,O43684,P28074,P50748,P50402,P28070,Q92973,Q96IY1 36
Pten regulation 0.2295019107662222 0.0431013505036709 0.965620742755172 1.0 1.0 65 P28074,P43686,Q86YP4,P28072,Q6IAA8,P25787,P28070,O00231,P49721 9
Rmts methylate histone arginines 0.2083029302930113 0.0409691457927521 0.9673204932918542 1.0 1.0 19 P11802,P62805 2
E2f mediated regulation of dna replication 0.2428193446528972 0.0408779505092705 0.9673931956963452 1.0 1.0 11 P30153,P06400,Q9Y619,P30154,P06493 5
Nucleotide excision repair 0.2171712956639021 0.0408344179588177 0.967427900668898 1.0 1.0 56 P18887,Q9Y265,P54727,O75925,P61088,Q99627,Q07864,P41208,P18858,Q9Y2S7,Q13619,P41440 12
Deubiquitination 0.2373980017550467 0.040725072829233 0.9675150729461964 1.0 1.0 99 Q9NXR7,P43686,Q9Y265,P62195,Q5VVQ6,Q12834,Q9Y4E8,Q14997,Q96K76,Q15388,O00231,P49721,P62191,O43242,P06493,P21796,Q969V5,O95630,P28072,P25787,P54578,O60493,Q14318,P28074,P54727,Q13546,P28070,P45880 28
Mapk family signaling cascades 0.2390392316475486 0.040694234201814 0.9675396582301474 1.0 1.0 89 P43686,Q9NZI8,P62195,Q14997,Q13813,P18206,P30154,Q01082,O00231,Q16181,P49721,P31946,Q9Y4G8,Q96P70,P62191,O43242,P06493,P30153,P28072,P25787,O60725,P28074,Q14738,P28070,P25685,P51665,Q14168,Q9HCE1 28
Dna replication 0.2363682034623629 0.0392184536103268 0.9687162211007324 1.0 1.0 92 P43686,Q9UJX5,P62195,Q9Y248,P49736,Q9Y2S7,P35251,O00231,Q7L590,P49721,Q07864,P62191,Q9BRT9,P62805,P28072,P25787,P63208,P41440,Q9UJX4,P28074,P24941,Q9Y619,P28070,P18858 24
Mitotic g2 g2 m phases 0.2360041713104515 0.03896959527277 0.9689146296495053 1.0 1.0 86 O75935,Q9NYZ3,P28072,Q9H6D7,P25787,P28070,P41208,Q13561,O00231,Q99640,P49721 11
Antigen processing ubiquitination proteasome degradation 0.2317047186314506 0.0379361542477344 0.9697385868647244 1.0 1.0 98 P43686,Q9UJX5,P62195,Q12834,Q8TDB6,O00231,Q14139,P49721,Q7Z6Z7,P62191,P55786,O43242,P61088,Q8TB52,P28072,P25787,P63208,Q96J02,Q16763,Q9UJX4,Q5T447,P28074,Q9UBS8,P28070,Q9UIQ6 25
Intracellular signaling by second messengers 0.2340995079892665 0.0379220855195375 0.9697498040142428 1.0 1.0 85 P28074,P43686,P52292,Q86YP4,P19174,P10644,P28072,Q6IAA8,P25787,P28070,O43865,O00231,P49721 13
Dna repair 0.2035102285836542 0.0373280624909212 0.9702234304481744 1.0 1.0 115 P20585,P18887,Q9Y265,O96028,Q9UQ84,Q9Y2S7,Q07864,P41208,P62805,O00213,P29372,P61088,Q12888,Q6P6C2,P41440,P54727,P52292,O75925,P24941,Q99627,P18858,Q13619,P12956 23
Sumoylation of dna methylation proteins 0.2974954184483765 0.0360455098041224 0.9712460709374418 1.0 1.0 4 Q99496,Q9HC52,P26358 3
S phase 0.2250356429901328 0.035398129532886 0.9717622761952848 1.0 1.0 97 P43686,Q9UJX5,P62195,Q9Y248,P49736,Q9Y2S7,P35251,O00231,Q29RF7,P49721,P11802,P06400,Q07864,P62191,Q9BRT9,P28072,P25787,P63208,P41440,Q9UJX4,P28074,P24941,Q9Y619,P28070,P18858 25
Signaling by receptor tyrosine kinases 0.1879769405239975 0.0352047719300912 0.9719164571415286 1.0 1.0 111 P31946,Q96JJ3,Q9UQB8,Q8IV63,P36543,P21281,P16949,O43865,P51812,Q13464 10
Rho gtpase effectors 0.1928680619588497 0.034695033895571 0.972322920922222 1.0 1.0 109 P31946,Q9UQB8,Q13464,Q12834,Q6IPU0,Q9Y266,Q92674,Q96IY1,P62805 9
Signaling by mapk mutants 0.4068986568986588 0.0341201443881823 0.9727813449376816 1.0 1.0 2 Q99956 1
Separation of sister chromatids 0.2009258101870077 0.0338058668217111 0.9730319575740036 1.0 1.0 105 P43686,Q9UJX5,Q9Y6G9,P62195,Q12834,Q14997,Q9Y266,P30154,O00231,Q29RF7,P49721,Q92674,P62191,O43242,Q15691,P30153,Q14204,Q6IPU0,Q8NFH4,P28072,P25787,Q16763,Q71F23,Q9UJX4,O43684,P28074,P50748,Q14738,P28070,P51665,Q96IY1 31
Mitotic prometaphase 0.2241949443211373 0.0335460592122165 0.973239136542726 1.0 1.0 88 Q9Y6G9,Q12834,Q9Y266,P30154,Q15021,Q29RF7,P17612,P14635,O75935,Q15154,Q92674,P41208,Q15691,P06493,Q9BW27,P30153,Q14203,Q14204,Q6IPU0,Q8NFH4,Q13561,O95347,Q96CW5,Q71F23,O43684,Q14980,P50748,Q14738,Q9NTJ3,Q9H6D7,Q96IY1 31
Nef and signal transduction 0.4047619047619067 0.0334159143981816 0.9733429188953472 1.0 1.0 2 Q13177 1
Synthesis of dna 0.2232694375002977 0.0330132754066918 0.9736640011687328 1.0 1.0 86 P43686,Q9UJX5,P62195,Q14997,Q9Y248,P49736,Q9Y2S7,P35251,O00231,P49721,P33993,Q07864,P62191,O43242,Q9BRT9,P28072,P25787,P63208,Q16763,P41440,Q9UJX4,P28074,P24941,Q9Y619,P28070,P18858 26
Maturation of sars cov 1 nucleoprotein 0.4017094017094036 0.0324541097540621 0.9741099118446386 1.0 1.0 2 P49841 1
L1cam interactions 0.1796166466341189 0.0290519556403086 0.9768231534513614 1.0 1.0 39 P15311,P51812,P35241 3
Mitotic prophase 0.2021292726126414 0.027398896434299 0.978141578437364 1.0 1.0 59 Q8TEM1,Q92621,P30154,Q9BTX1,Q08379,O60763,P14635,P06400,Q8N1F7,Q99567,Q7Z3B4,P06493,P62805,P42167,P30153,P20700,Q8NFH4,O95347,Q14980,P50402,P12270,Q9NTJ3,Q6IBW4 23
Disorders of transmembrane transporters 0.1984944845670478 0.0260488281308708 0.9792183924309564 1.0 1.0 78 P28074,P53985,P43686,P08195,P62195,Q8TEM1,P28072,P12270,P25787,P28070,P62191,Q8N1F7,O43242,Q99567,Q9BTX1,O00231,Q9UBV2,P49721 18
Rhou gtpase cycle 0.2020822187904561 0.0255725372081782 0.9795982910373752 1.0 1.0 17 O43396,Q13813,Q14155,Q8WUY9 4
Estrogen dependent nuclear events downstream of esr membrane signaling 0.3636641221373939 0.0254065028958028 0.9797307242226868 1.0 1.0 3 P28482,P31751 2
Ra biosynthesis pathway 0.3578625954198359 0.0239621963180156 0.980882763010122 1.0 1.0 3 Q8NBN7,Q9HBH5 2
Wax and plasmalogen biosynthesis 0.2748930971288884 0.0235047661317587 0.9812476367130404 1.0 1.0 4 O00116,Q6IAN0,O15228 3
Cytosolic sulfonation of small molecules 0.2624503513596167 0.020421804005922 0.9837068903949112 1.0 1.0 5 Q8TB61,O43252,O95340,O95861 4
Robo receptors bind akap5 0.3113553113553134 0.0197981995776555 0.9842043541318486 1.0 1.0 2 P17612 1
Sema3a plexin repulsion signaling by inhibiting integrin adhesion 0.3297709923664019 0.0188570611221706 0.9849551337046648 1.0 1.0 3 Q9Y490,P63000 2
Nf kb activation through fadd rip 1 pathway mediated by caspase 8 and 10 0.2403787416004846 0.0122859115912072 0.9901975074305652 1.0 1.0 4 Q14258,Q13546,Q9Y6K9 3
Degradation of cysteine and homocysteine 0.2354917532070811 0.0112872947154741 0.9909942330406852 1.0 1.0 4 Q9UBX3,P00505,P32929 3
Signaling by cytosolic fgfr1 fusion mutants 0.2198677276696563 0.0104784067627006 0.9916395940137696 1.0 1.0 8 Q9UBW7 1
Traf6 mediated nf kb activation 0.2405256723716377 0.0093597329815608 0.9925321225976718 1.0 1.0 6 Q9Y6K9,Q12933,P05067,Q14258,P09429 5