| Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size |
| Sphingolipid metabolism integrated pathway 0.8614424207117558 2.542627427446644 0.0110022475167059 0.9986902669299113 0.5072075735334153 8 O15269,P27544,O95470,Q13510,Q06136,Q96G23 6 |
| Sphingolipid metabolism overview 0.8614424207117558 2.542627427446644 0.0110022475167059 0.9986902669299113 0.5072075735334153 8 O15269,P27544,O95470,Q13510,Q06136,Q96G23 6 |
| Cholesterol biosynthesis with skeletal dysplasias 0.8585762190468876 2.494754853601923 0.0126044176685964 0.9995048829334824 0.5072075735334153 7 Q14739,Q15392,Q15125,Q9UBM7,Q16850 5 |
| Glycosaminoglycan degradation 0.8535669271762836 2.4410981558084592 0.0146426742787646 0.9998566987956392 0.5072075735334153 6 P06865,P15586,P54802,P16278 4 |
| Degradation pathway of sphingolipids including diseases 0.820813346585856 2.326642069903235 0.0199843234654428 0.9999945069482852 0.5072075735334153 7 P06280,P06865,P16278,P17900 4 |
| Cholesterol metabolism with bloch and kandutschrussell pathways 0.6040405324155576 2.2543309311965145 0.0241753568402209 0.9999995801744476 0.5072075735334153 25 Q14739,P48449,Q15392,Q15125,Q9UBM7,Q14534,Q15800,O75845,Q16850,P37268 10 |
| Proteoglycan biosynthesis 0.9227917458238372 2.2504251825277133 0.0244219679262687 0.9999996392491006 0.5072075735334153 4 Q8NCH0,Q8TB61 2 |
| Kennedy pathway from sphingolipids 0.8553555080866756 2.206128069802638 0.0273750338408902 0.999999941487598 0.5072075735334153 5 P35790,P48651,O95470,Q9BVG9 4 |
| Sphingolipid metabolism in senescence 0.76257202886112 2.198718717629399 0.0278979291871759 0.9999999576239014 0.5072075735334153 11 Q13510,P04062,P16278,Q06136,Q96G23 5 |
| Oxidation by cytochrome p450 0.7873988148067983 2.147366500806952 0.0317641153882382 0.9999999961211354 0.5150937630525113 6 Q16850,Q6UW02,O43169 3 |
| Sphingolipid pathway 0.7516274524809203 2.070842906399884 0.0383734790893013 0.999999999936341 0.5154362049597484 9 O15269,O95470,Q13510,P04062,Q06136,Q96G23 6 |
| Mitochondrial complex iv assembly 0.7437433528580273 2.06787184889331 0.0386520752018122 0.9999999999464996 0.5154362049597484 10 P14406,Q9Y2R0,P13073,Q9Y241 4 |
| Omega3 omega6 fatty acid synthesis 0.740433766606521 1.932997045448818 0.0532365617703389 0.9999999999999944 0.5413887637661591 6 O15254,Q15067 2 |
| Glycerophospholipid biosynthetic pathway 0.7023673631813376 1.8325783936493332 0.0668652937336342 1.0 0.5899878858850082 9 P48651,Q9HCL2,O00116,Q9BTU6,O95674,O15228,O14735 7 |
| Ferroptosis 0.5756754233109556 1.7880832189186011 0.0737625825818173 1.0 0.5986304937865852 22 Q9UKU0,P16435,P45880,P02786,P09601,Q9NZ45,Q9Y277,P37268 8 |
| Overlap between signal transduction pathways contributing to lmna laminopathies 0.6553638376649511 1.7775287310754966 0.0754812880000366 1.0 0.6038503040002929 14 O60725,P55209,P50402,O75844,P11802 5 |
| Mitochondrial complex iii assembly 0.6815582739092998 1.7607079964415064 0.0782878386207124 1.0 0.6100351061354216 10 O14949,Q9UDW1 2 |
| Electron transport chain oxphos system in mitochondria 0.4690269066594896 1.6916329504103802 0.0907159798470069 1.0 0.6470492684914786 48 O43674,O14949,Q9UDW1,P00403,P56385,P24539,P03886,O75306,P06576,P14406,O75964,O43676,O95169,P13073 14 |
| Influence of laminopathies on wnt signaling 0.6676739417128932 1.6909617454793855 0.0908441091359946 1.0 0.6470492684914786 10 O75844,O60725 2 |
| Triacylglyceride synthesis 0.7325999586492918 1.670095049937603 0.0949005593787502 1.0 0.6470492684914786 5 Q9HCL2,O00116,Q9NUQ2 3 |
| Oxidative phosphorylation 0.4273154107178863 1.59518700556732 0.1106704237007247 1.0 0.6762595436420759 31 Q15904,P24539,P03886,O75306,P06576,O75964,O95169,P56385 8 |
| Vitamin d metabolism 0.947240012198842 1.586425564395059 0.1126428050780936 1.0 0.6762595436420759 3 P04062,P38435 2 |
| Striated muscle contraction pathway 0.660845694611656 1.559485143589913 0.1188815981392528 1.0 0.6762595436420759 6 P08670 1 |
| Acquired partial lipodystrophy barraquersimons syndrome 0.7554871542194296 1.5555226030547176 0.1198216556643543 1.0 0.6762595436420759 4 O60725,Q03252 2 |
| Statin inhibition of cholesterol production 0.7043167918783384 1.5431642497117806 0.1227909289901445 1.0 0.6762595436420759 5 Q8WTV0,P37268 2 |
| Cholesterol biosynthesis pathway 0.6073253294776454 1.515616262347418 0.1296164125313978 1.0 0.6762595436420759 14 O75845,Q9UBM7,Q14534,Q15800,Q16850,P37268 6 |
| Ccl18 signaling pathway 0.6212717272316154 1.42955779902183 0.1528439749104488 1.0 0.7280218999152234 9 P00403,P11166,P33176,P08670,Q86UE4 5 |
| Mitochondrial complex i assembly model oxphos system 0.4315659021918877 1.3832307778311002 0.1665941153618362 1.0 0.7280218999152234 29 O43674,Q9NPL8,Q96CU9,Q9P0J0,P03886,O75306,O43676,O95169 8 |
| Metabolism of spingolipids in er and golgi apparatus 0.8825861543153313 1.3392573282475837 0.1804869151851851 1.0 0.7417270487062402 3 Q06136,O95470 2 |
| Familial partial lipodystrophy fpld 0.5985873854957932 1.276023462741492 0.2019472252027205 1.0 0.8035187998709833 7 O75844,O60725,Q03252,P20700 4 |
| Ketogenesis and ketolysis 0.5884069448782089 1.2113641258581478 0.2257558820114449 1.0 0.8413262683656333 6 P23786,P11166,P53985,O43772 4 |
| Glycerolipids and glycerophospholipids 0.5735064654675365 1.1530118521432704 0.2489055197971674 1.0 0.8733527010426929 7 P48651,Q9HCL2,Q9BVG9,O14735,Q9UG56 5 |
| 1q211 copy number variation syndrome 0.5658203217916741 1.1491402610527268 0.2504981492008125 1.0 0.87383075302609 9 P54619,Q07157,Q16625,Q9NPH0,P35222 5 |
| Eicosanoid metabolism via lipooxygenases lox 0.5735388864515478 1.139527989565606 0.2544830009357699 1.0 0.8775275894336895 6 O15254,Q8N8N7 2 |
| Oxysterols derived from cholesterol 0.5538867777352363 1.0568593137300422 0.2905757994819027 1.0 0.9057863376727916 7 Q15125 1 |
| Interactions between loxl4 and oxidative stress pathway 0.6349908926206806 1.0396902397538297 0.2984838365976923 1.0 0.9057863376727916 4 Q16543 1 |
| Photodynamic therapyinduced nfe2l2 nrf2 survival signaling 0.5524795946558445 1.0379177560222317 0.2993083462632289 1.0 0.9057863376727916 6 P09601 1 |
| Metapathway biotransformation phase i and ii 0.4725012016674372 0.989507319428516 0.3224149905056297 1.0 0.9174916160567504 20 Q8NCH0,P78417,Q6UW02,Q16850,P07099,Q7LGA3 6 |
| Arrhythmogenic right ventricular cardiomyopathy 0.5110544494883421 0.9822767758190036 0.3259635127332787 1.0 0.9225382435847512 14 P02545,P16615,O43707,P50402,P12814,P19022,P35222 7 |
| Nanomaterial induced apoptosis 0.5646780802230371 0.9107353483386018 0.3624348344154291 1.0 0.9626612755763954 5 Q9NR28 1 |
| Vitamin d receptor pathway 0.5067194999497372 0.9067134714806604 0.3645583376141483 1.0 0.9626612755763954 12 P20020,Q8IWT6,Q96KA5,P08183 4 |
| Endothelin pathways 0.5149732201033184 0.8675547116577508 0.3856381481720303 1.0 0.9740544640718274 7 P00403,P42892 2 |
| Phase i biotransformations non p450 0.7541257461484693 0.8558022711460145 0.3921071587759646 1.0 0.9740544640718274 3 Q15165 1 |
| Type i collagen synthesis in the context of osteogenesis imperfecta 0.4979452862309853 0.8403415116237354 0.4007169326470099 1.0 0.9740544640718274 11 Q32P28,P13674,Q96AY3 3 |
| Thermogenesis 0.3648517027723273 0.8223201686652805 0.4108947009144847 1.0 0.9901077130469512 29 P23786,O43772 2 |
| Vitamin a and carotenoid metabolism 0.7436831738532079 0.8179079425034058 0.4134097547532607 1.0 0.9921834114078256 3 Q8WTV0 1 |
| Progeriaassociated lipodystrophy 0.4962349298388911 0.7997534002617238 0.4238536869817018 1.0 1.0 9 O75844,O60725,Q03252 3 |
| Neuroinflammation 0.5742798286681524 0.7854212613832036 0.4322066189917521 1.0 1.0 4 P00403 1 |
| 7oxoc and 7betahc pathways 0.4896196235810748 0.7672031574228898 0.4429607359272012 1.0 1.0 9 Q15125,Q9UBM7 2 |
| 15q112 copy number variation syndrome 0.567913672953336 0.7594218155257578 0.4476002675699562 1.0 1.0 4 Q96CW5,Q7L576 2 |
| Mitochondrial long chain fatty acid betaoxidation 0.4691285215168593 0.7533734370362769 0.4512255403259169 1.0 1.0 14 P23786,Q16836,O43772 3 |
| Nonalcoholic fatty liver disease 0.3636323728342182 0.7429395128280577 0.457518302020107 1.0 1.0 49 O14949,Q9UDW1,P00403,Q9P0J0,O75306,P14406,O43676,O95169,P13073 9 |
| Disruption of postsynaptic signaling by cnv 0.4844616833643504 0.7220365464951385 0.470272008474309 1.0 1.0 7 Q07157,Q13555,Q7L576 3 |
| Gastric cancer network 2 0.4581929975438517 0.7193876027385652 0.4719021332114075 1.0 1.0 15 Q03252,Q14739,Q86UE4 3 |
| Camkk2 pathway 0.4673091734172827 0.7016150043588979 0.4829192918455356 1.0 1.0 12 Q13501,P42345,O76024,Q14012,O00429,P09601 6 |
| Glycosylation and related congenital defects 0.4669936228700292 0.6833120550842641 0.4944096782574472 1.0 1.0 11 O60762,Q9BV10,Q9H0U3,Q13724,Q9BT22,Q2TAA5 6 |
| Cohesin complex cornelia de lange syndrome 0.4494768670341565 0.6721245959045011 0.5015043794757159 1.0 1.0 15 P30154,Q29RF7,P30153,Q9UQE7,P06493 5 |
| Omega9 fatty acid synthesis 0.4745341392653572 0.6696234458958931 0.5030978640231858 1.0 1.0 6 O95864 1 |
| Nad metabolism 0.5427387417690204 0.6584409669401893 0.5102548183942708 1.0 1.0 4 P43490 1 |
| Regulation of apoptosis by parathyroid hormonerelated protein 0.4941268227760308 0.604543757130374 0.5454821866181561 1.0 1.0 5 Q9BXK5 1 |
| Relationship between inflammation cox2 and egfr 0.680809080500467 0.598820006319587 0.5492929196205854 1.0 1.0 3 Q9H7Z7 1 |
| Eicosanoid metabolism via cyclooxygenases cox 0.4538075263418532 0.5762077421616264 0.5644747727444375 1.0 1.0 6 O15254,Q8N8N7 2 |
| Pregnane x receptor pathway 0.5181980909286973 0.5635003368417163 0.5730942307853342 1.0 1.0 4 P08183 1 |
| Rala downstream regulated genes 0.5169116112407576 0.5586367428920113 0.5764096586322829 1.0 1.0 4 P11233 1 |
| Nephrotic syndrome 0.4245374401125441 0.5207268272767934 0.6025570831308629 1.0 1.0 14 Q14108 1 |
| Cannabinoid receptor signaling 0.4731876944997881 0.5191064507933886 0.603686510138421 1.0 1.0 5 Q8NCG7 1 |
| Nuclear receptors in lipid metabolism and toxicity 0.8070121951219658 0.5171766383875652 0.605032858490119 1.0 1.0 2 P08183 1 |
| Urea cycle and related diseases 0.8036585365853979 0.5078198180070151 0.6115797101434106 1.0 1.0 2 Q9Y619 1 |
| Mitochondrial immune response to sarscov2 0.4348721387361198 0.5076506861063939 0.611698337840263 1.0 1.0 9 Q99623 1 |
| Proximal tubule transport 0.423498384220267 0.4568256846119367 0.6477963429150451 1.0 1.0 9 P08183,P11166,P36543,P08195 4 |
| Insulin signaling in adipocytes normal condition 0.4868722119744542 0.4489047392097843 0.6535003771605119 1.0 1.0 4 P31751 1 |
| Insulin signaling in adipocytes diabetic condition 0.4868722119744542 0.4489047392097843 0.6535003771605119 1.0 1.0 4 P31751 1 |
| Apoptosisrelated network due to altered notch3 in ovarian cancer 0.4018636245425481 0.4099488794874903 0.6818434480707478 1.0 1.0 14 P05067 1 |
| Nocgmppkg mediated neuroprotection 0.4372912133982488 0.3818420392209052 0.7025785343661965 1.0 1.0 5 P30536 1 |
| Reninangiotensinaldosterone system raas 0.4651494728785463 0.3748835416546414 0.7077470798035128 1.0 1.0 4 Q14012,Q13555 2 |
| Tyrobp causal network in microglia 0.4348489472077919 0.3730099188792427 0.7091410616821965 1.0 1.0 5 Q5T1M5,P61916,Q15758,Q15418 4 |
| Mfap5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement 0.4339431449354828 0.3697525079244493 0.7115669043540753 1.0 1.0 5 Q07157,P12814,P18206 3 |
| Constitutive androstane receptor pathway 0.4267232759603614 0.3441525959330364 0.730731530122813 1.0 1.0 5 P08183 1 |
| Inhibition of exosome biogenesis and secretion by manumycin a in crpc cells 0.3945773544108236 0.3303677227691757 0.7411221271607844 1.0 1.0 7 P20339,P31943,O14964 3 |
| Caloric restriction and aging 0.4481241697276124 0.320582138138814 0.7485270754288931 1.0 1.0 4 P43490 1 |
| Osx and mirnas in tooth development 0.7210365853658534 0.3017592311360875 0.7628356117184207 1.0 1.0 2 P35222 1 |
| Joubert syndrome 0.3750872464958306 0.2887353257013597 0.7727839274790285 1.0 1.0 14 P41208,P36404 2 |
| Allograft rejection 0.3808925036641902 0.2886867880856663 0.7728210740211767 1.0 1.0 11 P10321,P04439,P08670,P08183 4 |
| Congenital generalized lipodystrophy cgl 0.7143292682926827 0.287374882277458 0.7738252914857591 1.0 1.0 2 P31751 1 |
| Signal transduction through il1r 0.4231238560097703 0.2476042350753864 0.8044406336339402 1.0 1.0 4 Q16539,Q9BQ95,Q9H0E2 3 |
| G1 to s cell cycle control 0.3033723696004933 0.2004232209263795 0.8411496002372796 1.0 1.0 26 P33993,Q99640,P11802,Q14566,Q9Y619,P06493 6 |
| Mthfr deficiency 0.3563509820231272 0.1925173550509402 0.8473369748086541 1.0 1.0 9 P49419,P35790,P21964 3 |
| Primary focal segmental glomerulosclerosis fsgs 0.3403383331445632 0.1903732618611203 0.8490166484566988 1.0 1.0 18 Q14108,Q9NVD7,O43707,P08670 4 |
| Adipogenesis 0.3443858595593412 0.1827062154174974 0.8550285386574925 1.0 1.0 16 O75844,Q9NZ45 2 |
| Interleukin1 induced activation of nfkb 0.6570121951219545 0.1809550990993956 0.8564028198295723 1.0 1.0 2 P61088 1 |
| Mechanoregulation and pathology of yaptaz via hippo and nonhippo mechanisms 0.3499236641221153 0.1738587424304686 0.8619764775152632 1.0 1.0 7 Q13177,P35221,P05556,P35222,P27348,Q9Y6E0 6 |
| Fluoropyrimidine activity 0.3420810147099343 0.1494326965640156 0.8812122132392248 1.0 1.0 12 P31350,P18074,Q92820,P00374 4 |
| Somatroph axis gh and its relationship to dietary restriction and aging 0.6173780487805056 0.1253071991815026 0.9002803529861314 1.0 1.0 2 P42345 1 |
| Apoptosis modulation and signaling 0.3324919183580329 0.1248110787417375 0.9006731164126613 1.0 1.0 14 Q9NR28,O95831 2 |
| H19 action rbe2f1 signaling and cdkbetacatenin activity 0.3315018315018336 0.1237707881879707 0.9014967615813378 1.0 1.0 6 Q16527,O75367,P35222,P11802,Q15648 5 |
| Vitamin dsensitive calcium signaling in depression 0.3331305952613632 0.1217666880196128 0.9030837966951152 1.0 1.0 8 P23634,Q8NB78 2 |
| Ppar signaling pathway 0.3220971885763907 0.1175947016913344 0.9063888032554333 1.0 1.0 18 O15254,P23786,O95864,Q9UKU0,Q15067,O14975 6 |
| Folate metabolism 0.324558426867349 0.1092841517185539 0.912977116399158 1.0 1.0 16 P00374 1 |
| Mir124 predicted interactions with cell cycle and differentiation 0.5954268292682924 0.1007170028032532 0.9197751137226792 1.0 1.0 2 P26599 1 |
| Copper homeostasis 0.3204539476237582 0.0953434595778487 0.9240420241077532 1.0 1.0 6 P05067 1 |
| Nephrogenesis 0.5896341463414698 0.0949380062493855 0.9243640682203168 1.0 1.0 2 Q04721 1 |
| Hedgehog signaling pathway wp47 0.580182926829268 0.0861230815468381 0.9313685753703392 1.0 1.0 2 Q96ST3 1 |
| Angiopoietinlike protein 8 regulatory pathway 0.2682318196157883 0.080438897604127 0.9358881913050384 1.0 1.0 28 Q15642,Q14254,P11166,P42345,P41440,P31751,O00767,Q9UPT5 8 |
| Praderwilli and angelman syndrome 0.3171645272981215 0.0795600965546296 0.9365871329047216 1.0 1.0 8 P11802,Q7L576 2 |
| Amyotrophic lateral sclerosis als 0.3181420498455437 0.0762477924352217 0.9392219604615056 1.0 1.0 11 Q9BUN8 1 |
| Nodlike receptor nlr signaling pathway 0.5557926829268289 0.0667216315427302 0.9468033132022078 1.0 1.0 2 Q96RT1 1 |
| Ovarian infertility 0.4435367344464282 0.0636377463473043 0.949258675402169 1.0 1.0 3 P11802 1 |
| Nongenomic actions of 125 dihydroxyvitamin d3 0.3038167938931206 0.052708386132024 0.9579642571487524 1.0 1.0 7 Q13557,Q13555,Q15648,Q16539,P42224,Q96JM3 6 |
| Estrogen receptor pathway 0.4310626126776531 0.0526043720009366 0.9580471334430232 1.0 1.0 3 Q15067 1 |
| Dna replication 0.2495962265993132 0.0515534221535606 0.9588845336882936 1.0 1.0 30 Q9Y619 1 |
| Osteoblast differentiation and related diseases 0.3039095907147184 0.0488225659531155 0.961060698586602 1.0 1.0 8 Q99570,P78527,O00443,P35222,Q04721,Q16539,P42224 7 |
| Synaptic signaling pathways associated with autism spectrum disorder 0.3040024442407621 0.045575184500926 0.9636488485136698 1.0 1.0 9 P54619,Q15334,P49841,P42345,Q13131,Q8N122,P21359,P31751 8 |
| Microglia pathogen phagocytosis pathway 0.3129957291031166 0.0401398624666651 0.967981621743402 1.0 1.0 4 O00443,P63000,P07948 3 |
| Resistin as a regulator of inflammation 0.3036313701556102 0.0351114670804286 0.9719908576432994 1.0 1.0 5 Q9Y6K9,Q16539,P31751,P19174 4 |
| Ebsteinbarr virus lmp1 signaling 0.3035387431360667 0.0310616712953424 0.9752203567846592 1.0 1.0 4 Q9Y6K9,P07900,Q9NR12 3 |
| Wntbetacatenin signaling pathway in leukemia 0.3833485818847202 0.0234653131347514 0.9812791069703666 1.0 1.0 3 P35222,P14923 2 |
| Endochondral ossification 0.2938663411656915 0.0221551336978444 0.9823242069188174 1.0 1.0 5 Q9Y376,Q01581,P50454,P42224 4 |
| Endochondral ossification with skeletal dysplasias 0.2938663411656915 0.0221551336978444 0.9823242069188174 1.0 1.0 5 Q9Y376,Q01581,P50454,P42224 4 |
| Follicle stimulating hormone fsh signaling pathway 0.2938663411656889 0.022155133697841 0.98232420691882 1.0 1.0 5 P62753,Q16539,P42345,P28482 4 |
| Proteasome degradation 0.2527671534687826 0.0218959052524538 0.9825309911285124 1.0 1.0 41 P28074,P28072,P25787,P49721,O00231,P04843,P48556,O43242,P01889,P51665,P04439,P28070,Q9UL46,P10321,Q06323,P20618 16 |
| Regulation of wnt bcatenin signaling by small molecule compounds 0.3832317073170726 0.0196147405945638 0.984350704801761 1.0 1.0 2 P35222 1 |
| Id signaling pathway 0.3310975609756091 0.0185247114274756 0.9852202640780388 1.0 1.0 2 P24941 1 |
| Mammalian disorder of sexual development 0.300914634146341 0.0183558011132019 0.9853550120977864 1.0 1.0 2 P35222 1 |
| Nad biosynthetic pathways 0.2766337041797677 0.0080393462623526 0.9935855988333496 1.0 1.0 6 P43490 1 |
| Vitamin b12 disorders 0.2891125343092398 0.0047974149744876 0.9961722313429016 1.0 1.0 3 Q99707,P22033 2 |
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