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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:708ccff3aecf2f56b168f9f9f8e90e0aee79bc49016636c2c0a8d51b6355af05
+size 83512

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

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+{
+    "type_of_task": "ranksum",
+    "signature_size": 3447,
+    "annotations_size": 57,
+    "title": "Average number of proteins per term",
+    "value": 2.9649122807017543
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C044/C044_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Serine carboxypeptidase, serine active site [IPR018202]	0.904521497948026	1.4557462790281648	0.145462771340763	0.9998715700511654	0.2961206416579818	3	Q9HB40	1
+Histidine acid phosphatase active site [IPR033379]	0.8763425253991509	1.4344905449371217	0.1514323253638561	0.999913874933168	0.2976428464048206	2	Q9NPH0	1
+Ribonucleotide reductase small subunit, acitve site [IPR030475]	0.7419448476052222	0.8877626439545739	0.3746684410420657	0.9999999999976106	0.5084785985570893	2	Q7LG56	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CASP7", "CASP8", "CDK1", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK8", "CDK9", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EGFR", "EIF2AK2", "EPHA2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "JAK1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR1", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK1", "NEK9", "NME1", "NME2", "NME3", "OXCT1", "OXSM", "PAK2", "PASK", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN9", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYK2", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["ACP6", "RRM2B", "SCPEP1"]}

interpro_binding_site/advanced/idx2term.json

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+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:8f0147cf56ff0724738c3a666ada16c9cbdbf74997d1da2a9e8a8fc570174288
+size 80593

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,3 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+EF-Hand 1, calcium-binding site [IPR018247]	15	39	2.185251211283213	0.028870432502186	10.019417475728156	36.70631067961165	0.9532938980945532	0.3894555773109194	3.76037227687173	3.057484685571999	1.1082350706804749	0.3408841825650379	0.3688651156930481	0.3121781622201707	0.5314369287659462	0.0028924350901622	9.112965697295094e-05
+Beta tubulin, autoregulation binding site [IPR013838]	4	6	2.1421562097915774	0.0321809139643061	3.5533980582524274	5.54126213592233	0.5823511994709325	0.3808337519133083	1.5578062452886454	0.9632803779920796	1.1906256051626651	0.3058955364405814	1.0	1.0	0.0824659877424542	3.788095303003865e-05	2.7217956886305476e-05

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3447,
+    "annotations_size": 33,
+    "title": "Average number of proteins per term",
+    "value": 5.090909090909091
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C044/C044_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,3 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+EF-Hand 1, calcium-binding site [IPR018247]	0.5195527811091584	2.185251211283213	0.028870432502186	0.6196820325713079	0.1058582525080154	39	P41208,Q9Y680,O43852,O95302,O75746,P80303,Q9BPX6,Q9BRK5,Q14257,Q9NWM8,Q9UBC2,P0DP25,O95202,Q02818,P43304	15
+Beta tubulin, autoregulation binding site [IPR013838]	0.8351731802534614	2.1421562097915774	0.0321809139643061	0.6602120132330227	0.1061970160822101	6	P07437,Q13885,P04350,Q9BUF5	4

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Aryldialkylphosphatase, zinc-binding site [IPR017947]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APEX2", "APOBEC3C", "ARAF", "ARG2", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK8", "CDK9", "CEP97", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "EGFR", "EHD1", "EHD4", "EIF2AK2", "EPHA2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "JAK1", "LETM1", "LYN", "MACF1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO9B", "NEK1", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PASK", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRKCSH", "PSAT1", "PTER", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK1", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TYK2", "UBE3C", "ULK3", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["CALM3", "CALU", "CETN2", "EPS15L1", "FKBP14", "FKBP7", "FKBP9", "GPD2", "LETM1", "MICU1", "NUCB1", "NUCB2", "RCN2", "SDF4", "SLC25A12", "TUBB", "TUBB2A", "TUBB4A", "TUBB6"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Intermediate filament protein, conserved site [IPR018039]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Intermediate filament protein, conserved site [IPR018039]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:efbc087d10a2cca64ff65c3e20ac9850e6e899552db2731b66a0d9eb26eb0044
+size 105068

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Intermediate filament protein, conserved site [IPR018039]	6	8	2.3450053156639723	0.0190268083322169	4.060679611650485	7.546116504854369	0.7869831563787604	0.2926647109331939	1.9153715257926656	0.8924219614624045	1.3691577499316503	0.3120813432784052	1.0	1.0	1.0	0.0688460117016781	1.151824294970335e-05
+Tubulin, conserved site [IPR017975]	4	6	2.1421562097915747	0.0321809139643063	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.0	1.0	0.1581956798045988	0.0007750266814789	0.0012892425867137
+Proteasome beta-type subunit, conserved site [IPR016050]	2	8	2.090418672857631	0.03658020696197	3.7135922330097086	7.970873786407767	1.4913184573846054	0.1902243906475925	1.515457478026574	0.1681602725795027	1.0170822776023185	0.2455850375425174	0.0014378644617379	0.0461123069087121	9.54357461344528e-05	0.0014684283121974	0.000884326619221

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3447,
+    "annotations_size": 288,
+    "title": "Average number of proteins per term",
+    "value": 2.736111111111111
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C044/C044_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,30 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Intermediate filament protein, conserved site [IPR018039]	0.8164618185261497	2.3450053156639723	0.0190268083322169	0.9960440022565548	0.1191243652104016	8	P48681,Q16352,P08670,Q03252,P07197,P07196	6
+Tubulin, conserved site [IPR017975]	0.8351731802534611	2.1421562097915747	0.0321809139643063	0.999918955314613	0.1519361183888561	6	P07437,Q13885,P04350,Q9BUF5	4
+Proteasome beta-type subunit, conserved site [IPR016050]	0.761095743122612	2.090418672857631	0.03658020696197	0.9999781786022984	0.1672238032547202	8	P28072,P49721	2
+Guanylate kinase, conserved site [IPR020590]	0.773349107634666	1.8753294662238316	0.0607474120192617	0.999999985501225	0.2158412012675756	6	Q14168,Q12959	2
+Haem oxygenase conserved site [IPR018207]	0.9808417997097268	1.8672151245052209	0.06187155234356	0.9999999897306248	0.2158412012675756	2	P30519	1
+Thioredoxin, conserved site [IPR017937]	0.6658420970978421	1.8376945413617125	0.066107428682206	0.9999999972105846	0.2225232099901735	10	Q9H3N1,Q9H1E5,O95881	3
+Syntaxin/epimorphin, conserved site [IPR006012]	0.7586417629192076	1.5959896224323915	0.1104911102984433	0.9999999999999978	0.3051792472857027	5	Q13190,Q9P2W9	2
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.8885341074020427	1.4850873061950822	0.1375206982172674	1.0	0.3414306990221812	2	Q16836	1
+C-type lectin, conserved site [IPR018378]	0.8444121915820019	1.302257623791294	0.1928283325714694	1.0	0.4175530810570166	2	Q9UBG0	1
+Sterol reductase, conserved site [IPR018083]	0.8568358383342767	1.2738561336065708	0.2027144070792013	1.0	0.4356846958120147	3	Q9UBM7	1
+DnaJ domain, conserved site [IPR018253]	0.4988473556721927	1.0495667884823674	0.29391733323413	1.0	0.5395642393203917	11	Q9Y2G8,Q9UDY4,Q99543,Q9NVH1	4
+Chromo domain, conserved site [IPR023779]	0.5853935340964136	1.02908033014904	0.3034419283996366	1.0	0.5496306627616059	6	P83916,Q13185	2
+Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]	0.6497450388509747	0.949676506358312	0.342276650852912	1.0	0.5905480534538539	4	P48735	1
+Mini-chromosome maintenance, conserved site [IPR018525]	0.5480268250187228	0.8600807863613557	0.38974451165998	1.0	0.6305978615622149	6	P33991,Q14566	2
+Dynamin, GTPase region, conserved site [IPR019762]	0.6470246734397639	0.5403717085310923	0.588940714576935	1.0	0.7644902077644437	2	P50570	1
+Aldehyde dehydrogenase, cysteine active site [IPR016160]	0.4193472932077551	0.3981482982258462	0.6905208741583675	1.0	0.8391139736608011	7	P51648	1
+Heat shock protein Hsp90, conserved site [IPR019805]	0.5854019228834961	0.3430658089911596	0.7315489523997931	1.0	0.8636451822394368	3	P14625	1
+Acyl-CoA dehydrogenase, conserved site [IPR006089]	0.4040435721107678	0.3354027522950323	0.7373212920534049	1.0	0.8667287024954311	7	P49748,Q9H845	2
+ABC transporter-like, conserved site [IPR017871]	0.3601082674562076	0.2911390659251384	0.7709449630756433	1.0	0.8845902365170728	11	O75027,P08183,P33527,P28288	4
+AT hook, DNA-binding motif [IPR017956]	0.5541364296081224	0.2745537268247414	0.7836591211225146	1.0	0.8938066987952159	2	P17096	1
+DNA topoisomerase, type IIA, conserved site [IPR018522]	0.4978229317851899	0.1654014629914235	0.8686280022353245	1.0	0.9658875082771176	2	P11388	1
+Cyclic nucleotide-binding, conserved site [IPR018488]	0.4838896952104435	0.1449890729366265	0.8847194991586178	1.0	0.9695948926462786	2	P13861	1
+Ras GTPase-activating protein, conserved site [IPR023152]	0.3938425791460929	0.1295374036516693	0.8969324304252579	1.0	0.9784717422820997	4	P46940,Q86VI3,P21359	3
+Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]	0.4519593613933181	0.1075706709817078	0.9143362631244484	1.0	0.9886415579711326	2	Q8WVM0	1
+DNA mismatch repair, conserved site [IPR014762]	0.4264150943396164	0.0861632678115926	0.931336630117512	1.0	0.9886415579711326	2	Q86VD7	1
+Ribosomal S11, conserved site [IPR018102]	0.4029027576197336	0.0721367833852986	0.9424930535555068	1.0	0.9886415579711326	2	P82912	1
+Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]	0.3529753265602261	0.0557438227708389	0.9555458882325744	1.0	0.9886415579711326	2	P29692	1
+DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]	0.2966618287372936	0.0498106254124378	0.9602732993406164	1.0	0.9886415579711326	2	O15160	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.3954703832752648	0.0486737538476115	0.9611792924719345	1.0	0.9886415579711326	3	Q9BXS5,Q96CW1	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "2-5-oligoadenylate synthetase, C-terminal  conserved site [IPR006117]", "2-5-oligoadenylate synthetase, N-terminal conserved site [IPR043518]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kank N-terminal motif [IPR021939]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site [IPR018168]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABR", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ARRB2", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BARD1", "BAZ1A", "BAZ1B", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ6", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DTL", "DTYMK", "DUS2", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FBXW11", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXK2", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXA10", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "ING5", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "IVD", "KANK2", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAGI3", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRC2", "MRPL13", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NET1", "NF1", "NKTR", "NLE1", "NMT1", "NMT2", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSD3", "NSF", "NUBP2", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OAS3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBFA", "RCL1", "RDH13", "RDX", "RECQL5", "RELA", "RIDA", "RIOK2", "RNF114", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SH3RF1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX18", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAF5L", "TAP2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP34", "USP38", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VAV2", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR55", "WDR61", "WDR77", "WDR83", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ABCB7", "ABCC1", "ABCD3", "ACAD9", "ACADVL", "ALDH3A2", "AP1M1", "AP2M1", "CBX1", "CBX3", "DHCR7", "DLG1", "DNAJB4", "DNAJC11", "DNAJC16", "DNAJC2", "DNM2", "EEF1D", "HADH", "HMGA1", "HMOX2", "HSP90B1", "IDH2", "INA", "IQGAP1", "IQGAP3", "LMNB2", "MCM4", "MCM6", "MPP2", "MRC2", "MRPS11", "NEFL", "NEFM", "NES", "NF1", "POLR1C", "PRKAR2A", "PSMB2", "PSMB6", "SLC25A42", "STX18", "STX5", "TFB1M", "TMX1", "TMX4", "TOP2A", "TUBB", "TUBB2A", "TUBB4A", "TUBB6", "TXNDC12", "VIM"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "RNA recognition motif domain [IPR000504]", "1": "EF-hand domain [IPR002048]", "2": "Intermediate filament, rod domain [IPR039008]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "RNA recognition motif domain [IPR000504]", "1": "EF-hand domain [IPR002048]", "2": "Intermediate filament, rod domain [IPR039008]", "3": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "4": "K Homology domain, type 1 [IPR004088]", "5": "K Homology domain [IPR004087]", "6": "Thioredoxin domain [IPR013766]", "7": "Histidine kinase/HSP90-like ATPase [IPR003594]", "8": "DnaJ domain [IPR001623]", "9": "WW domain [IPR001202]", "10": "Ubiquitin-like domain [IPR000626]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:a6029d8164f936737158c9b7d4680523953234e95a38c66ccb73c9667106d35f
+size 356291

interpro_domain/df_merge.tsv

@@ -0,0 +1,12 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+RNA recognition motif domain [IPR000504]	47	120	3.319696835087915	0.0009011525148854	39.713592233009706	116.0	0.2316956716939257	0.5316884276370477	13.873754985119357	5.729331786381952	1.713447249572458	0.3950212299678106	1.0	1.0	1.0	0.000296699420546	1.6164687893565614e-12
+EF-hand domain [IPR002048]	18	47	2.390825956568773	0.0168105196611727	12.385922330097088	43.512135922330096	1.0171858714399242	0.3947118087831401	4.608360476919044	4.087317384177653	1.201458704248258	0.3652478399429377	0.4418810859000467	0.3776146865859943	0.2461545823107532	0.0028229234797234	2.0765030437009743e-05
+Intermediate filament, rod domain [IPR039008]	6	8	2.3450053156639723	0.0190268083322169	4.060679611650485	7.546116504854369	0.7869831563787604	0.2926647109331939	1.9153715257926656	0.8924219614624045	1.3691577499316503	0.3120813432784052	1.0	1.0	1.0	0.097689242801984	5.2157456419384365e-05
+GOLD domain [IPR009038]	3	7	2.144292855189891	0.0320094289402055	2.8762135922330097	6.247572815533981	0.4192390492462461	0.3068843884052658	1.4199402534298398	0.930533270242389	1.3963570929114475	0.294203492723015	1.0	1.0	1.0	0.2721697661507766	0.0026822887756782
+Tubulin/FtsZ, GTPase domain [IPR003008]	4	6	2.1421562097915747	0.0321809139643063	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.0	1.0	0.1581956798045988	0.0007750266814789	0.0012892425867137
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	4	6	2.1421562097915747	0.0321809139643063	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	1.0	1.0	0.1500965904253892	0.0006143549700213	0.0009690980868318
+Zinc finger, RanBP2-type [IPR001876]	4	9	2.1045012244243564	0.035334747918021	3.2742718446601944	8.616504854368932	0.6239078002715212	0.4100405386528319	1.463145369641179	0.7330740021954685	1.0299872364022182	0.3121093098016552	1.0	1.0	1.0	0.0133829456596615	0.0165469565809516
+Major facilitator superfamily domain [IPR020846]	2	6	2.091671900031801	0.036467875844496	1.8883495145631068	4.121359223300971	0.8776223597987594	0.2728824130413255	1.233496960525634	1.4580976091979958	1.2936014196902064	0.266909732326598	0.1599975741724403	0.1321770275159086	0.2496255286594674	0.0348798008289802	0.1736998940434156
+RNA recognition motif domain, eukaryote [IPR003954]	3	12	2.0265477871479387	0.0427086809006018	4.084951456310679	13.157766990291265	0.4053633607283609	0.5044278905686779	2.611599730621696	1.3534791070715837	0.9876170990304802	0.3281969373801077	1.0	1.0	1.0	0.0901924811619011	0.0165469565809516
+Amine oxidase [IPR002937]	2	5	1.9943763751143904	0.046110938338852	0.720873786407767	2.900485436893204	0.5827071427294988	0.4712976716648685	0.8630782646239248	0.6515848917425413	1.0085176998749834	0.3167184226135821	1.0	1.0	0.0013106969968569	0.0002629541815867	0.0019903460540529
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	3	5	1.9896451976608096	0.0466300335475007	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0673062601152012	1.0	0.0001725606130307	0.0025975272437437	0.0019297769565794

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3447,
+    "annotations_size": 2818,
+    "title": "Average number of proteins per term",
+    "value": 2.22249822569198
+}

interpro_domain/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_domain/fragment/C044/C044_val_log2fc"}

interpro_domain/result.tsv

@@ -0,0 +1,229 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+RNA recognition motif domain [IPR000504]	0.5514089072587806	3.319696835087915	0.0009011525148854	0.9211803296627532	0.1266750985910202	120	P51991,P33240,O43347,Q8WXF1,P31942,Q8IXT5,P35637,P52597,P52272,P98175,Q13242,P38159,P23246,Q86V81,Q14011,O14979,Q9UKM9,P62995,Q16629,Q15233,P52756,Q92804,P22626,Q13151,Q01844,Q9UKA9,O75494,P31943,P55795,Q96PK6,Q15427,P43243,Q14103,O15047,A0AV96,O60506,Q8N684,O43390,P31483,Q07955,Q99729,P23588,Q13595,P07910,Q9BWF3,P98179,Q01085	47
+EF-hand domain [IPR002048]	0.5114287912865969	2.390825956568773	0.0168105196611727	1.0	0.1341984260770108	47	P41208,Q9Y680,O43852,O95302,O75746,O75071,P80303,Q66K14,Q9BPX6,Q9BRK5,Q6KCM7,Q9NWM8,Q14257,Q9UBC2,P0DP25,O95202,Q02818,P43304	18
+Intermediate filament, rod domain [IPR039008]	0.8164618185261497	2.3450053156639723	0.0190268083322169	1.0	0.141430694127922	8	P48681,Q16352,P08670,Q03252,P07197,P07196	6
+TRAM/LAG1/CLN8 homology domain [IPR006634]	0.9545069170967933	2.1784968737129877	0.0293690647309612	1.0	0.1661601987708926	4	Q15629,P27544	2
+GOLD domain [IPR009038]	0.790980912979713	2.144292855189891	0.0320094289402055	1.0	0.1711053123611608	7	Q9H3P7,Q9Y3B3,Q15363	3
+Tubulin/FtsZ, GTPase domain [IPR003008]	0.8351731802534611	2.1421562097915747	0.0321809139643063	1.0	0.1711053123611608	6	P07437,Q13885,P04350,Q9BUF5	4
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	0.8351731802534611	2.1421562097915747	0.0321809139643063	1.0	0.1711053123611608	6	P07437,Q13885,P04350,Q9BUF5	4
+Zinc finger, RanBP2-type [IPR001876]	0.7459019721977993	2.1045012244243564	0.035334747918021	1.0	0.1810423993326969	9	P35637,Q01844,Q92804,P52756	4
+Major facilitator superfamily domain [IPR020846]	0.823342612118741	2.091671900031801	0.036467875844496	1.0	0.1836856132853906	6	Q7L0J3,P53985	2
+RNA recognition motif domain, eukaryote [IPR003954]	0.6644416968334226	2.0265477871479387	0.0427086809006018	1.0	0.19491634188421	12	P38159,P31483,Q14011	3
+Amine oxidase [IPR002937]	0.8537558227406561	1.9943763751143904	0.046110938338852	1.0	0.2027154824319579	5	O60341,Q6QHF9	2
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	0.85260686580966	1.9896451976608096	0.0466300335475007	1.0	0.2039632125210104	5	Q9UMX5,O43169,O15173	3
+SET domain [IPR001214]	0.6591147695333348	1.939958440166738	0.0523847408651014	1.0	0.2186248416587011	11	Q9H7B4,Q03164	2
+Peptidase M1, membrane alanine aminopeptidase [IPR014782]	0.7839717686337183	1.9216970505617872	0.0546438886033646	1.0	0.2233912900357971	6	P55786,Q9NZ08,Q9UIQ6,Q6P179	4
+Aminopeptidase N-like , N-terminal domain [IPR045357]	0.7839717686337183	1.9216970505617872	0.0546438886033646	1.0	0.2233912900357971	6	P55786,Q9NZ08,Q9UIQ6,Q6P179	4
+GMP phosphodiesterase, delta subunit [IPR008015]	0.988098693759073	1.897052358757078	0.057821028064926	1.0	0.2307927154206255	2	O43924	1
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	0.7779715199069923	1.895532015063898	0.0580219544445654	1.0	0.231267139497575	6	Q9HD20,P23634,P16615,P98194,P05023	5
+LEM domain [IPR003887]	0.7759967606689366	1.8869060549789112	0.0591729625681776	1.0	0.2331293639947425	6	Q86XL3,P42167	2
+ERAP1-like C-terminal domain [IPR024571]	0.8687191402846471	1.840098860158293	0.0657537246201176	1.0	0.2431679737263667	4	P55786,Q9NZ08,Q9UIQ6	3
+Band 7 domain [IPR001107]	0.7060930561542458	1.8300847155421824	0.0672372720922445	1.0	0.2463909398646879	8	P27105,Q9UJZ1,O75955	3
+Intermediate filament head, DNA-binding domain [IPR006821]	0.86349114144642	1.8191622242030423	0.0688866841753395	1.0	0.2511783622333795	4	Q16352,P08670,P07196	3
+RBM3/CIRBP, RNA recognition motif [IPR034278]	0.951523947750365	1.7462759461237254	0.0807630135099057	1.0	0.2709446580108733	2	P98179	1
+Phospholipase D/Transphosphatidylase [IPR001736]	0.9506531204644412	1.7426751479648417	0.0813903751135516	1.0	0.2717512761492754	2	Q8N2A8	1
+Guanylate kinase-like domain [IPR008144]	0.6984238185481226	1.7174526891403823	0.0858964917050311	1.0	0.280987661505944	7	Q14168,Q12959,Q5TCQ9	3
+Guanylate kinase/L-type calcium channel beta subunit [IPR008145]	0.6984238185481226	1.7174526891403823	0.0858964917050311	1.0	0.280987661505944	7	Q14168,Q12959,Q5TCQ9	3
+Peptidase M28 [IPR007484]	0.9677700348431996	1.6965543951298263	0.0897809380256799	1.0	0.2878301289605986	3	Q7Z2K6,P02786	2
+FAD dependent oxidoreductase [IPR006076]	0.8313624203948298	1.6898041863620503	0.0910654226525724	1.0	0.289968769531016	4	Q96CU9	1
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	0.7777454968041817	1.6770120876676102	0.0935401181666986	1.0	0.2915885541966335	5	P23634,P16615,P98194,P05023	4
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	0.7777454968041817	1.6770120876676102	0.0935401181666986	1.0	0.2915885541966335	5	P23634,P16615,P98194,P05023	4
+Fatty acid hydroxylase [IPR006694]	0.9343976777939133	1.675387207728214	0.0938582848559712	1.0	0.2922570682034552	2	Q15800	1
+Heterogeneous nuclear ribonucleoprotein Q acidic domain [IPR041337]	0.9338171262699568	1.6729817607107398	0.0943308867033598	1.0	0.2934044577594571	2	O60506	1
+Acyl transferase [IPR014043]	0.9332365747460138	1.670576172840385	0.0948054220998213	1.0	0.2942309245344675	2	P49327	1
+Mitochondrial outer membrane transport complex Sam37/metaxin, N-terminal domain [IPR019564]	0.9268505079825886	1.6441059572972891	0.1001543176337884	1.0	0.3051187752346117	2	Q13505	1
+Metaxin, glutathione S-transferase domain [IPR033468]	0.9268505079825886	1.6441059572972891	0.1001543176337884	1.0	0.3051187752346117	2	Q13505	1
+L27 domain [IPR004172]	0.8145951014376054	1.621866116455947	0.1048320179704807	1.0	0.313605760765196	4	Q12959	1
+Polyketide synthase, enoylreductase domain [IPR020843]	0.7105621873882778	1.5972005062469778	0.1102210199195856	1.0	0.3245588653431477	6	Q8N4Q0,P49327	2
+FAD linked oxidase, N-terminal [IPR006094]	0.9117561683599502	1.5814884652957324	0.1137663942725029	1.0	0.3288324712540265	2	Q15392	1
+FAD-binding domain, PCMH-type [IPR016166]	0.9117561683599502	1.5814884652957324	0.1137663942725029	1.0	0.3288324712540265	2	Q15392	1
+CARG-binding factor, N-terminal [IPR012956]	0.901015965166912	1.536905996263949	0.124316330926367	1.0	0.343791384249757	2	Q99729	1
+Tim44-like domain [IPR007379]	0.8984034833091509	1.526060081051179	0.1269949024102672	1.0	0.3481652057081553	2	O43615	1
+Heat shock chaperonin-binding [IPR006636]	0.7882435645518688	1.5146040339165434	0.1298727100287413	1.0	0.3529231406566954	4	P54727,P54725	2
+Zinc finger, CHHC-type [IPR012996]	0.9189895470383236	1.5109492320582794	0.1308013860635908	1.0	0.3551043409703265	3	P31943,P55795	2
+3-hydroxyacyl-CoA dehydrogenase, C-terminal [IPR006108]	0.8885341074020427	1.4850873061950822	0.1375206982172674	1.0	0.3647626915171954	2	Q16836	1
+3-hydroxyacyl-CoA dehydrogenase, NAD binding [IPR006176]	0.8885341074020427	1.4850873061950822	0.1375206982172674	1.0	0.3647626915171954	2	Q16836	1
+Marvel domain [IPR008253]	0.8853410740203187	1.471833107387624	0.1410659508754146	1.0	0.3680776384878874	2	Q16625	1
+GYF domain [IPR003169]	0.880116110304789	1.450148093524807	0.1470172261250537	1.0	0.3778532314623211	2	Q6Y7W6	1
+K Homology domain, type 1 [IPR004088]	0.492086543725911	1.4485259505906865	0.1474700137603042	1.0	0.3784795070824565	22	Q07666,Q06787,Q96AE4,Q96I24,Q9Y2W6,Q15637,P51114,P61978,Q92945,Q96PU8	10
+Chromo domain [IPR023780]	0.6402947196003951	1.440560380426864	0.1497089202362298	1.0	0.3802798531734635	7	P83916,Q13185,Q14839	3
+CNNM, transmembrane domain [IPR002550]	0.8777939042090102	1.4405122332579572	0.1497225315121493	1.0	0.3802798531734635	2	Q8NE01	1
+Ion transporter-like, CBS domain [IPR044751]	0.8777939042090102	1.4405122332579572	0.1497225315121493	1.0	0.3802798531734635	2	Q8NE01	1
+Peptidase M16, N-terminal [IPR011765]	0.640234484487122	1.4402705934300288	0.1497908577084969	1.0	0.3802798531734635	7	O75439,Q5JRX3,Q10713	3
+Peptidase M16, C-terminal [IPR007863]	0.640234484487122	1.4402705934300288	0.1497908577084969	1.0	0.3802798531734635	7	O75439,Q5JRX3,Q10713	3
+MD-2-related lipid-recognition domain [IPR003172]	0.8676342525399121	1.3983749752798034	0.1620004938794856	1.0	0.3986087706618887	2	P61916	1
+ATPase family AAA domain-containing protein 3, N-terminal [IPR021911]	0.8647314949201848	1.386343173926012	0.165642139489287	1.0	0.4030911477381787	2	Q5T9A4	1
+SWIRM domain [IPR007526]	0.7543459521388796	1.3759938463969816	0.1688235384212051	1.0	0.4074451882247243	4	O60341,Q8NB78	2
+Fzo/mitofusin HR2 domain [IPR006884]	0.8583454281567481	1.3598880019029822	0.1738653683442759	1.0	0.4131134974655729	2	Q8IWA4	1
+Chromo/chromo shadow domain [IPR000953]	0.5917074236828557	1.3352861448416178	0.1817827115427626	1.0	0.4223113611933264	9	P83916,P45973,Q13185,Q14839	4
+Fibronectin type II domain [IPR000562]	0.8499274310595055	1.325052791141348	0.1851536424967741	1.0	0.4269746027462434	2	Q9UBG0	1
+CD209-like, C-type lectin-like domain [IPR033989]	0.8444121915820019	1.302257623791294	0.1928283325714694	1.0	0.4346673601043608	2	Q9UBG0	1
+C-type lectin-like [IPR001304]	0.8444121915820019	1.302257623791294	0.1928283325714694	1.0	0.4346673601043608	2	Q9UBG0	1
+Immunoglobulin C1-set [IPR003597]	0.8432510885341062	1.2974618281318198	0.1944723309074651	1.0	0.4346673601043608	2	P10321	1
+MHC class I, alpha chain, C-terminal [IPR010579]	0.8432510885341062	1.2974618281318198	0.1944723309074651	1.0	0.4346673601043608	2	P10321	1
+MHC class I alpha chain, alpha1 alpha2 domains [IPR001039]	0.8432510885341062	1.2974618281318198	0.1944723309074651	1.0	0.4346673601043608	2	P10321	1
+OCRE domain [IPR041591]	0.8426705370101586	1.2950643700400868	0.1952980248092393	1.0	0.4350591572430327	2	P52756	1
+Peptidase M3A/M3B catalytic domain [IPR001567]	0.8613913216721856	1.2912054910332031	0.1966324315694456	1.0	0.4373403253059967	3	Q99797	1
+K Homology domain [IPR004087]	0.4676466211025636	1.276217413252073	0.2018786747514807	1.0	0.4437551524568429	22	Q07666,Q06787,Q96AE4,Q96I24,Q9Y2W6,Q15637,P51114,P61978,Q92945,Q96PU8	10
+Zinc finger C2H2 AKAP95-type [IPR034736]	0.8519163763066131	1.2551326693459626	0.2094306026624077	1.0	0.454330591457017	3	Q5BKZ1,Q9ULX6	2
+Oxidoreductase, N-terminal domain [IPR041694]	0.8296081277213397	1.2412080540015928	0.2145289003176556	1.0	0.462188410623206	2	Q14914	1
+Reticulon [IPR003388]	0.8478513356561969	1.2396718821889203	0.2150967812711064	1.0	0.4628834013183146	3	O95197,Q9NQC3	2
+Matrin/U1-C, C2H2-type zinc finger [IPR000690]	0.629837966348571	1.231683903773139	0.2180671848658288	1.0	0.4658933487125897	6	Q12874	1
+Chromo domain subgroup [IPR017984]	0.8449477351916375	1.2286350595304063	0.2192086643943716	1.0	0.4662502212083484	3	P83916,Q13185	2
+Chromo shadow domain [IPR008251]	0.8449477351916375	1.2286350595304063	0.2192086643943716	1.0	0.4662502212083484	3	P83916,Q13185	2
+ABC transporter type 1, transmembrane domain [IPR011527]	0.5915680285697242	1.2048048437121317	0.2282786496744995	1.0	0.4779266231669685	7	O75027,P08183,P33527,P28288	4
+NOPS [IPR012975]	0.8373983739837316	1.199968209310588	0.230151687296046	1.0	0.4804203368890798	3	Q8WXF1,P23246	2
+Far upstream element-binding protein, C-terminal [IPR015096]	0.81509433962264	1.1816025233910408	0.2373634518243177	1.0	0.4905672315885114	2	Q96AE4	1
+Tripartite DENN domain [IPR037516]	0.8259633233252415	1.156639622778124	0.2474196268574022	1.0	0.5008508070034109	3	A4D1U4	1
+Patatin-like phospholipase domain [IPR002641]	0.8087082728592436	1.155471795090749	0.2478972762093518	1.0	0.5008508070034109	2	Q9NP80	1
+XPC-binding domain [IPR015360]	0.8066763425253975	1.1471713445620342	0.2513108121855623	1.0	0.5039898943319928	2	P54725	1
+RAD23A/RAD23B, UBA1 domain [IPR041811]	0.8066763425253975	1.1471713445620342	0.2513108121855623	1.0	0.5039898943319928	2	P54725	1
+Alcohol dehydrogenase-like, C-terminal [IPR013149]	0.5691701551602372	1.095934945364709	0.2731072448401503	1.0	0.5295424362585756	7	Q14914,Q8N4Q0,P49327	3
+Ricin B, lectin domain [IPR000772]	0.6825685310171253	1.0824121818952377	0.2790694177051058	1.0	0.5335262001987708	4	Q10472,Q9UBG0	2
+Sorting nexin Vps5-like, C-terminal [IPR015404]	0.6806943653010827	1.0747902511044904	0.282468646133089	1.0	0.5351364431064305	4	Q9UNH7,Q9Y5X3	2
+Myosin, N-terminal, SH3-like [IPR004009]	0.6354360243632428	1.0672424178410829	0.2858623826752375	1.0	0.5351364431064305	5	P35580,Q9UM54	2
+Prolyl 4-hydroxylase, alpha subunit [IPR006620]	0.5937161088184372	1.0669631840183886	0.2859884610781704	1.0	0.5351364431064305	6	Q32P28	1
+Oxoglutarate/iron-dependent dioxygenase [IPR005123]	0.5937161088184372	1.0669631840183886	0.2859884610781704	1.0	0.5351364431064305	6	Q32P28	1
+Fragile X-related 1 protein, C-terminal region 1 [IPR032172]	0.7860667634252612	1.0634194829890868	0.2875917612282532	1.0	0.5362965476897356	2	P51114	1
+Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]	0.562321426900686	1.062650176299064	0.2879406233692583	1.0	0.5362965476897356	7	O60313,O95140,Q8IWA4,P50570	4
+Dynamin, N-terminal [IPR045063]	0.562321426900686	1.062650176299064	0.2879406233692583	1.0	0.5362965476897356	7	O60313,O95140,Q8IWA4,P50570	4
+Thioredoxin domain [IPR013766]	0.4290099411068779	1.053604201844638	0.2920641646494704	1.0	0.5383415590833232	24	Q9H1E5,O95881,Q9BS26,Q9Y2G8,Q9H3N1,Q6ZRP7,O43396,Q6DKJ4	8
+Plasma membrane calcium transporting P-type ATPase, C-terminal [IPR022141]	0.7770682148040617	1.0271419891527287	0.3043536093626751	1.0	0.5483813754373519	2	P23634	1
+Synaptic functional regulator FMRP, KH0 domain [IPR040472]	0.7862950058071976	1.0075872020425214	0.3136526753772413	1.0	0.5551795861083468	3	Q06787,P51114	2
+Fragile X-related 1 protein, C-terminal core [IPR022034]	0.7862950058071976	1.0075872020425214	0.3136526753772413	1.0	0.5551795861083468	3	Q06787,P51114	2
+Agenet-like domain [IPR008395]	0.7862950058071976	1.0075872020425214	0.3136526753772413	1.0	0.5551795861083468	3	Q06787,P51114	2
+Fxr1, tudor domain [IPR041560]	0.7862950058071976	1.0075872020425214	0.3136526753772413	1.0	0.5551795861083468	3	Q06787,P51114	2
+N-acetylgalactosaminyltransferase [IPR045885]	0.7628447024673564	0.9702340233111976	0.3319298552061154	1.0	0.5742040098040719	2	Q10472	1
+Isopropylmalate dehydrogenase-like domain [IPR024084]	0.6497450388509747	0.949676506358312	0.342276650852912	1.0	0.5859876075962978	4	P48735	1
+Transcription factor CBF/NF-Y/archaeal histone domain [IPR003958]	0.7564586357039179	0.944878045142838	0.3447211413527555	1.0	0.5887419250497364	2	Q9NR33	1
+HIT-like domain [IPR011146]	0.7480406386067027	0.9116597997695204	0.3619478322128777	1.0	0.6016781329414188	2	Q9NQE9	1
+Lamin tail domain [IPR001322]	0.7531939605110152	0.8854714261204454	0.3759024241032822	1.0	0.6132340495402762	3	P20700,Q03252	2
+MCM N-terminal domain [IPR027925]	0.5480268250187228	0.8600807863613557	0.38974451165998	1.0	0.6226190668128252	6	P33991,Q14566	2
+MCM OB domain [IPR033762]	0.5480268250187228	0.8600807863613557	0.38974451165998	1.0	0.6226190668128252	6	P33991,Q14566	2
+MCM domain [IPR001208]	0.5480268250187228	0.8600807863613557	0.38974451165998	1.0	0.6226190668128252	6	P33991,Q14566	2
+MCM, AAA-lid domain [IPR041562]	0.5480268250187228	0.8600807863613557	0.38974451165998	1.0	0.6226190668128252	6	P33991,Q14566	2
+CYRIA/CYRIB, Rac1 binding domain [IPR009828]	0.7444831591173049	0.8538083689029562	0.3932111766963575	1.0	0.6260277378137489	3	Q96F07,Q9NUQ9	2
+Cobalamin (vitamin B12)-binding domain [IPR006158]	0.7314949201741627	0.8471319113243863	0.3969215999257129	1.0	0.6294457335906917	2	Q99707	1
+Heterogeneous nuclear ribonucleoprotein U, SPRY domain [IPR035778]	0.7350272650002072	0.8197044761615506	0.4123845976609779	1.0	0.6352562993374153	3	Q1KMD3	1
+Myosin tail [IPR002928]	0.6164641157913143	0.8174689138349849	0.4136605071980685	1.0	0.6352562993374153	4	P35580	1
+Peptidase S54, rhomboid domain [IPR022764]	0.7222060957909986	0.8114042439526026	0.4171335627597647	1.0	0.6388491194875093	2	Q9H300	1
+Histidine kinase/HSP90-like ATPase [IPR003594]	0.4986914800814329	0.8017979855417241	0.4226698241222846	1.0	0.6409700155693682	8	P11388,Q12931,P14625,P08238,Q15120,Q15118,P07900	7
+Acyl-CoA oxidase/dehydrogenase, central domain [IPR006091]	0.4675008640192345	0.7760444166837284	0.4377227607240899	1.0	0.6547254457115103	10	P49748,Q9H845,Q15067,P16219	4
+MHC class I-like antigen recognition-like [IPR011161]	0.7125669013066751	0.7399782702992482	0.4593131795522835	1.0	0.6696040041274367	3	P10321	1
+Lysophosphatidylcholine acyltransferase LPCAT1-like [IPR045252]	0.7021770682148138	0.7357807964611817	0.4618641097785372	1.0	0.6702627819238091	2	Q86UL3	1
+Peptidase M41 [IPR000642]	0.7015965166908531	0.7336203690073013	0.4631801431385707	1.0	0.6707305464360186	2	Q9Y4W6	1
+ELMO domain [IPR006816]	0.7013062409288793	0.7325408638526796	0.4638385104862894	1.0	0.6709892003083079	2	Q8IZ81	1
+Glycerol-3-phosphate acyltransferase-like, C-terminal domain [IPR045520]	0.6975326560232396	0.7185508637109431	0.4724176977444783	1.0	0.6785285791253516	2	Q9HCL2	1
+GPAT/DHAPAT, acyltransferase domain [IPR041728]	0.6975326560232396	0.7185508637109431	0.4724176977444783	1.0	0.6785285791253516	2	Q9HCL2	1
+Peptidase S9, prolyl oligopeptidase, catalytic domain [IPR001375]	0.5892118611098325	0.7119602592456782	0.4764893854095593	1.0	0.6802673865814837	4	Q86TI2	1
+Post-SET domain [IPR003616]	0.5068871044019015	0.6781344595758201	0.4976864435102888	1.0	0.693610483586545	6	Q03164	1
+Zinc finger, CCHC-type [IPR001878]	0.4761375727203331	0.6503531199115049	0.5154641518495335	1.0	0.7034584055825174	7	Q9BWF3,Q9NUD5,Q16629	3
+Glycosyltransferase 2-like [IPR001173]	0.6846689895470259	0.6439751119100208	0.5195915729825957	1.0	0.7063237108851688	3	Q10471,Q10472	2
+4Fe-4S ferredoxin-type, iron-sulphur binding domain [IPR017896]	0.5668383715866446	0.6278921781189974	0.530074575365233	1.0	0.7136885587096161	4	P21912	1
+Legume-like lectin [IPR005052]	0.6699564586357004	0.619002276002115	0.5359148595116692	1.0	0.7153993719108875	2	Q12907	1
+Zinc finger, TFIIB-type [IPR013137]	0.6687953555878219	0.6149238211474178	0.5386050304058849	1.0	0.7176307213634912	2	P29083	1
+Sec23, C-terminal [IPR037550]	0.6603773584905921	0.5856550427965357	0.5581073512684724	1.0	0.7319478560868291	2	Q15437	1
+MRH domain [IPR044865]	0.5544048671416433	0.5824033787085784	0.5602950062598206	1.0	0.7327011582849823	4	Q13438	1
+SUN coiled coil domain 2 [IPR040994]	0.6592162554426948	0.581660446315727	0.5607954189343212	1.0	0.7327011582849823	2	Q9UH99	1
+FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]	0.4295941672112185	0.5751191629467554	0.565210708673038	1.0	0.7360276234013962	10	Q9Y680,Q9NWM8	2
+Ubiquitin carboxyl-terminal hydrolase, C-terminal [IPR029346]	0.6571843251088496	0.5746953750775062	0.5654973358911937	1.0	0.7360607355849348	2	Q93009	1
+SLC12A transporter, C-terminal [IPR018491]	0.6560232220609541	0.5707300398887458	0.5681826525918485	1.0	0.737624305077256	2	Q9BXP2	1
+Amino acid permease/ SLC12A domain [IPR004841]	0.6560232220609541	0.5707300398887458	0.5681826525918485	1.0	0.737624305077256	2	Q9BXP2	1
+Heat shock protein Hsp90, N-terminal [IPR020575]	0.550972988672684	0.5700221673918879	0.5686626631845368	1.0	0.737624305077256	4	P07900,Q12931,P14625	3
+CBS domain [IPR000644]	0.4566809150167201	0.561180146001086	0.5746747361731659	1.0	0.7409776488423039	7	Q8NE01,Q6P4Q7	2
+Exocyst complex component EXOC2/Sec5, N-terminal domain [IPR039481]	0.6525399129172673	0.5588992089401882	0.5762305093292532	1.0	0.7424786949476587	2	Q9UID3	1
+Dynamin GTPase effector [IPR003130]	0.6470246734397639	0.5403717085310923	0.588940714576935	1.0	0.7481256163170055	2	P50570	1
+Dynamin stalk domain [IPR000375]	0.6470246734397639	0.5403717085310923	0.588940714576935	1.0	0.7481256163170055	2	P50570	1
+GTPase effector domain [IPR020850]	0.6470246734397639	0.5403717085310923	0.588940714576935	1.0	0.7481256163170055	2	P50570	1
+FF domain [IPR002713]	0.64673439767779	0.5394036726837909	0.5896083474153813	1.0	0.7481256163170055	2	O75400	1
+Syntaxin, N-terminal domain [IPR006011]	0.646153846153865	0.5374697600537792	0.5909431677582258	1.0	0.7481256163170055	2	Q86Y82	1
+Dynamin, GTPase domain [IPR001401]	0.6472125435539995	0.5218183126173275	0.6017968380847207	1.0	0.755916420036411	3	O60313,P50570	2
+Desmoplakin, spectrin-like domain [IPR041573]	0.6437282229965182	0.5109203736829308	0.6094068143408218	1.0	0.7570392547791455	3	Q9UPN3,P15924	2
+Desmoplakin, SH3 domain [IPR041615]	0.6437282229965182	0.5109203736829308	0.6094068143408218	1.0	0.7570392547791455	3	Q9UPN3,P15924	2
+DnaJ domain [IPR001623]	0.3640578075702341	0.4975937117471278	0.618770436812772	1.0	0.7634373214596245	19	Q96KC8,Q13217,Q9UDY4,Q8IXB1,Q9UGP8,Q9Y2G8,Q99543,Q9NVH1,O75937	9
+PSP, proline-rich [IPR006568]	0.6267053701015924	0.4744218480305194	0.6351991161945092	1.0	0.772213593371927	2	Q13435	1
+WW domain [IPR001202]	0.3666394882414041	0.439288182767753	0.6604527357201306	1.0	0.7847049077678782	16	Q5TCQ9,Q9BTA9,P46939,O95817,P46934,P46940	6
+Plectin/S10, N-terminal [IPR005326]	0.615094339622637	0.43849780835189	0.6610254585446735	1.0	0.7849851420897135	2	Q15149	1
+JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]	0.4182946848016424	0.4189517592904983	0.6752513885557423	1.0	0.7937197618946704	8	Q92905,O15372,Q6P2Q9	3
+Arf GTPase activating protein [IPR001164]	0.4723997675769857	0.4106393897722071	0.6813369761624746	1.0	0.7966836509650843	5	Q8N6T3,Q8WU79,Q96P47,Q8IYB5	4
+ISWI, HAND domain [IPR015194]	0.6026124818577737	0.4014322276482548	0.688101925897695	1.0	0.8004639612687121	2	P28370	1
+SLIDE domain [IPR015195]	0.6026124818577737	0.4014322276482548	0.688101925897695	1.0	0.8004639612687121	2	P28370	1
+Phox homology [IPR001683]	0.3651606512752408	0.3352736528320211	0.7374186667053739	1.0	0.8335522674591832	12	Q9UNH7,Q9Y5X1,Q9Y5X3	3
+Protein kinase, C-terminal [IPR017892]	0.3966780238127103	0.30624337855072	0.7594193466445167	1.0	0.850912015445029	7	P51812	1
+Acyl-CoA dehydrogenase/oxidase, N-terminal [IPR013786]	0.3917358242863302	0.3042536368528334	0.760934664166232	1.0	0.8519324130395081	8	P49748,Q9H845,P16219	3
+Acyl-CoA dehydrogenase/oxidase C-terminal [IPR009075]	0.3917358242863302	0.3042536368528334	0.760934664166232	1.0	0.8519324130395081	8	P49748,Q9H845,P16219	3
+ABC transporter-like, ATP-binding domain [IPR003439]	0.3601082674562076	0.2911390659251384	0.7709449630756433	1.0	0.8610118684667611	11	O75027,P08183,P33527,P28288	4
+BAG domain [IPR003103]	0.4627910929559783	0.2866582544952008	0.774374004710717	1.0	0.8638899229116392	4	O95817	1
+MPN domain [IPR037518]	0.358466152422715	0.2831594310593743	0.7770546254990263	1.0	0.8651678920016815	11	Q92905,O15372,Q6P2Q9	3
+26S proteasome regulatory subunit Rpn7, N-terminal [IPR045135]	0.55471698113207	0.2759001742251218	0.7826247400927564	1.0	0.8703061741576171	2	Q13098	1
+Sterile alpha motif domain [IPR001660]	0.367555175749241	0.2700179137167305	0.7871464721613475	1.0	0.8728058944983648	10	Q9UQR0,Q8IXK0,P29317	3
+Helicase/SANT-associated domain [IPR014012]	0.5542973286875758	0.266770738032872	0.7896456856572964	1.0	0.8740068900951538	3	P51532,Q96L91	2
+eRF1 domain 3 [IPR005142]	0.5492017416545675	0.2632870441794444	0.7923293447693733	1.0	0.8752583667424908	2	Q9BRX2	1
+eRF1 domain 2 [IPR005141]	0.5492017416545675	0.2632870441794444	0.7923293447693733	1.0	0.8752583667424908	2	Q9BRX2	1
+eRF1 domain 1/Pelota-like [IPR005140]	0.5492017416545675	0.2632870441794444	0.7923293447693733	1.0	0.8752583667424908	2	Q9BRX2	1
+COMM domain [IPR017920]	0.5462989840348278	0.2568093473637583	0.7973259538709248	1.0	0.8787111998467994	2	Q9NX08	1
+NUC153 [IPR012580]	0.5419448476052195	0.2473024085666416	0.8046741949056972	1.0	0.8857702661110372	2	Q9BSC4	1
+Sec63 domain [IPR004179]	0.5397344534779098	0.2346787589700528	0.8144580752560482	1.0	0.894792536480134	3	Q9UGP8	1
+Man1/Src1, C-terminal [IPR018996]	0.5050798258345369	0.1770591975290994	0.8594618911406569	1.0	0.932814676531948	2	Q8NC56	1
+Ras GTPase-activating domain [IPR001936]	0.3939570017431678	0.1714815588813669	0.8638451295476766	1.0	0.9353327492131625	5	P46940,Q86VI3,Q14C86,P21359	4
+DNA topoisomerase 2, TOPRIM domain [IPR034157]	0.4978229317851899	0.1654014629914235	0.8686280022353245	1.0	0.9357009595944742	2	P11388	1
+C-terminal associated domain of TOPRIM [IPR031660]	0.4978229317851899	0.1654014629914235	0.8686280022353245	1.0	0.9357009595944742	2	P11388	1
+DNA topoisomerase, type IIA,  domain A [IPR002205]	0.4978229317851899	0.1654014629914235	0.8686280022353245	1.0	0.9357009595944742	2	P11388	1
+DNA topoisomerase, type IIA, subunit B, domain 2 [IPR013506]	0.4978229317851899	0.1654014629914235	0.8686280022353245	1.0	0.9357009595944742	2	P11388	1
+TOPRIM  domain [IPR006171]	0.4978229317851899	0.1654014629914235	0.8686280022353245	1.0	0.9357009595944742	2	P11388	1
+DTHCT [IPR012542]	0.4978229317851899	0.1654014629914235	0.8686280022353245	1.0	0.9357009595944742	2	P11388	1
+Zinc finger, UBP-type [IPR001607]	0.4960812772133467	0.162708888206508	0.8707476484778283	1.0	0.9358752762022688	2	Q53GS9	1
+Isochorismatase-like [IPR000868]	0.494920174165451	0.1609363718982437	0.8721435150459134	1.0	0.9358752762022688	2	Q96CN7	1
+EF-hand, Ca insensitive [IPR014837]	0.4997096399535461	0.1592293815486891	0.8734881560361816	1.0	0.936283614952438	3	Q13813,O43707	2
+SMCs flexible hinge [IPR010935]	0.3878558977338709	0.1565202797666159	0.8756229353006337	1.0	0.9365800526463488	5	A6NHR9,Q9NTJ3,Q9UQE7,Q14683	4
+Gamma tubulin complex component, C-terminal [IPR040457]	0.4914368650217645	0.1557266026253144	0.8762485271200784	1.0	0.9365800526463488	2	Q9BSJ2	1
+Gamma tubulin complex component protein, N-terminal [IPR041470]	0.4914368650217645	0.1557266026253144	0.8762485271200784	1.0	0.9365800526463488	2	Q9BSJ2	1
+cAMP-dependent protein kinase regulatory subunit, dimerization-anchoring domain [IPR003117]	0.4838896952104435	0.1449890729366265	0.8847194991586178	1.0	0.9394295787927956	2	P13861	1
+Immunoglobulin-like domain [IPR007110]	0.315516660054476	0.1425912560778663	0.8866130035513076	1.0	0.9396297269678768	15	Q92859,P04439,P10321,Q9BY67	4
+SAP domain [IPR003034]	0.3211347145992612	0.1377525070668262	0.8904360202830164	1.0	0.943035085058265	13	Q9BUJ2,P12956,Q1KMD3	3
+Phospholipid/glycerol acyltransferase [IPR002123]	0.3784445843607872	0.1346091659421608	0.8929208941980447	1.0	0.9445695282883472	5	Q9HCL2,Q86UL3,Q8NF37	3
+Survival motor neuron [IPR010304]	0.4679245283018802	0.1247021459328744	0.900759358455992	1.0	0.9508650016007496	2	Q16637	1
+MATH/TRAF domain [IPR002083]	0.4589259796806915	0.1146709542827164	0.9087059371500572	1.0	0.9558541735307432	2	Q93009	1
+Class II aldolase/adducin N-terminal [IPR001303]	0.4666085946573792	0.1112583447494648	0.9114114863414532	1.0	0.9576277287510124	3	Q9UEY8,P35611	2
+Longin domain [IPR010908]	0.4642857142857183	0.1083742149502627	0.913698854137344	1.0	0.9579805912999088	3	P51809,O15498	2
+v-SNARE, coiled-coil homology domain [IPR042855]	0.4642857142857183	0.1083742149502627	0.913698854137344	1.0	0.9579805912999088	3	P51809,O15498	2
+Ribosomal RNA adenine methylase transferase, N-terminal [IPR020598]	0.4519593613933181	0.1075706709817078	0.9143362631244484	1.0	0.9579805912999088	2	Q8WVM0	1
+Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding [IPR013155]	0.3487364900679905	0.1070339527934116	0.9147620440310258	1.0	0.9579805912999088	6	Q9NSE4	1
+Aminoacyl-tRNA synthetase, class Ia [IPR002300]	0.3487364900679905	0.1070339527934116	0.9147620440310258	1.0	0.9579805912999088	6	Q9NSE4	1
+Domain of unknown function DUF5600 [IPR040990]	0.4505079825834497	0.1061626063432378	0.9154533390507008	1.0	0.9579805912999088	2	Q9H4M9	1
+EH domain-containing protein, N-terminal [IPR031692]	0.4505079825834497	0.1061626063432378	0.9154533390507008	1.0	0.9579805912999088	2	Q9H4M9	1
+Disulphide isomerase [IPR005788]	0.3634514816966825	0.102693315085887	0.9182063793829148	1.0	0.9579805912999088	5	P13667,P30101,P07237,Q15084	4
+Serine/threonine-protein kinase N, C2 domain [IPR037784]	0.4426705370101527	0.0989711742423406	0.9211611573308348	1.0	0.959642196435598	2	Q16513	1
+Serine/threonine-protein kinase N, first HR1 domain [IPR037313]	0.4426705370101527	0.0989711742423406	0.9211611573308348	1.0	0.959642196435598	2	Q16513	1
+Ubiquitin conjugation factor E4, core [IPR019474]	0.4412191582002834	0.0977142163580121	0.9221592265606128	1.0	0.9601689115075324	2	O95155	1
+Ubiquitin-like domain [IPR000626]	0.2970119180424631	0.0801429608340819	0.9361235548088715	1.0	0.9716376344204052	18	Q15813,P54725,Q96S82,P54727,P46379	5
+TATA-binding protein interacting (TIP20) [IPR013932]	0.416255442670532	0.0794946689983857	0.9366391717187564	1.0	0.97181486962572	2	O75155	1
+Myb domain [IPR017930]	0.3297657205046584	0.0783434043311031	0.9375548918762686	1.0	0.9722462858843844	8	Q8TAQ2,Q99543	2
+NIPSNAP [IPR012577]	0.413933236574741	0.0781044112607262	0.9377449982376708	1.0	0.9722462858843844	2	O75323	1
+HHH domain 9 [IPR041692]	0.3991291727140708	0.0703239162394403	0.943935847221866	1.0	0.9768678727400728	2	Q7KZ85	1
+YqgF/RNase H-like domain [IPR006641]	0.3991291727140708	0.0703239162394403	0.943935847221866	1.0	0.9768678727400728	2	Q7KZ85	1
+Glycosyl transferase CAP10 domain [IPR006598]	0.3776487663280058	0.0619648772190428	0.9505908021478284	1.0	0.9820307487379266	2	Q7Z4H8	1
+Gelsolin-like domain [IPR007123]	0.328796182284776	0.0609131744630903	0.9514283572259776	1.0	0.9820307487379266	6	Q15437	1
+AMPK, C-terminal adenylate sensor domain [IPR032270]	0.3718432510885283	0.0602136792032086	0.9519854510551966	1.0	0.9820307487379266	2	P54646	1
+GCF, C-terminal [IPR022783]	0.4119356659582467	0.0588117268202193	0.9531020679777902	1.0	0.9820307487379266	3	Q9Y5B6	1
+Putative 5-3 exonuclease [IPR004859]	0.3625544267053643	0.0577959722871378	0.953911146467272	1.0	0.9820307487379266	2	Q9H0D6	1
+Xrn1, helical domain [IPR041412]	0.3625544267053643	0.0577959722871378	0.953911146467272	1.0	0.9820307487379266	2	Q9H0D6	1
+Matrin/U1-C-like, C2H2-type zinc finger [IPR003604]	0.3231596810635184	0.0577444185112293	0.9539522118462048	1.0	0.9820307487379266	9	Q96NB3,P43243,Q9ULV3	3
+Ancestral coatomer element 1, Sec16/Sec31 [IPR024298]	0.3547169811320695	0.0560863737724827	0.9552729990058576	1.0	0.9820307487379266	2	O15027	1
+Elongation factor 1 beta central acidic region, eukaryote [IPR018940]	0.3529753265602261	0.0557438227708389	0.9555458882325744	1.0	0.9820307487379266	2	P29692	1
+Translation elongation factor EF1B, beta/delta subunit, guanine nucleotide exchange domain [IPR014038]	0.3529753265602261	0.0557438227708389	0.9555458882325744	1.0	0.9820307487379266	2	P29692	1
+Coatomer, gamma subunit, appendage, Ig-like subdomain [IPR013040]	0.3230769230769169	0.0515805120832855	0.9588629477708204	1.0	0.9832881320299024	2	Q9Y678	1
+Coatomer subunit gamma, C-terminal [IPR032154]	0.3230769230769169	0.0515805120832855	0.9588629477708204	1.0	0.9832881320299024	2	Q9Y678	1
+Spen paralogue/orthologue C-terminal, metazoa [IPR010912]	0.3074020319303271	0.0503754504720718	0.959823199227278	1.0	0.9832968643272382	2	Q96T37	1
+DNA-directed RNA polymerase, RpoA/D/Rpb3-type [IPR011263]	0.2966618287372936	0.0498106254124378	0.9602732993406164	1.0	0.9832968643272382	2	O15160	1
+DNA-directed RNA polymerase, insert domain [IPR011262]	0.2966618287372936	0.0498106254124378	0.9602732993406164	1.0	0.9832968643272382	2	O15160	1
+RasGAP protein, C-terminal [IPR000593]	0.3937282229965197	0.0477318549504184	0.9619299464492168	1.0	0.9842841645221108	3	Q86VI3,P46940	2
+SCP2 sterol-binding domain [IPR003033]	0.3890824622531982	0.0453350938868558	0.9638402153070832	1.0	0.9853742357834714	3	P51659,Q6YN16	2
+Proteasome activator PA28, N-terminal domain [IPR003185]	0.3692371137079098	0.0368371617607846	0.9706148433452952	1.0	0.9902942174319486	3	Q06323	1
+Proteasome activator PA28, C-terminal domain [IPR003186]	0.3692371137079098	0.0368371617607846	0.9706148433452952	1.0	0.9902942174319486	3	Q06323	1
+Elongation factor EFG, domain V-like [IPR000640]	0.322388369940782	0.0343389442070327	0.9726068701833016	1.0	0.991249967514121	5	Q8N442	1
+NAD-dependent epimerase/dehydratase [IPR001509]	0.3498838559814213	0.0308926446687045	0.9753551558292152	1.0	0.9933324283074552	3	Q16795,Q9NRG7	2
+Band 4.1, C-terminal [IPR008379]	0.3368176538908292	0.027943682852067	0.9777070681552312	1.0	0.9950084933410768	3	Q9Y2J2,O43491	2
+SAB domain [IPR007477]	0.3368176538908292	0.027943682852067	0.9777070681552312	1.0	0.9950084933410768	3	Q9Y2J2,O43491	2
+Jumonji, helical domain [IPR041070]	0.3234610917537793	0.0256483865636511	0.9795377918515442	1.0	0.99651173192695	3	Q8NHM5,Q9UPP1	2
+IPT domain [IPR002909]	0.2608190531513186	0.0071926190760873	0.9942611697693828	1.0	1.0	4	Q9UIW2,Q96KP1,Q04206	3