ligdis commited on
Commit
a19e59b
·
verified ·
1 Parent(s): ae97018

Upload folder using huggingface_hub

Browse files
This view is limited to 50 files because it contains too many changes.   See raw diff
Files changed (50) hide show
  1. interpro_active_site/advanced/idx2term.json +1 -0
  2. interpro_active_site/basic/idx2term.json +1 -0
  3. interpro_active_site/basic/plot_0.png +3 -0
  4. interpro_active_site/consensus.joblib +3 -0
  5. interpro_active_site/df_merge.tsv +1 -0
  6. interpro_active_site/metrics.json +7 -0
  7. interpro_active_site/paths.json +1 -0
  8. interpro_active_site/result.tsv +6 -0
  9. interpro_active_site/selections.json +1 -0
  10. interpro_binding_site/advanced/idx2term.json +1 -0
  11. interpro_binding_site/basic/idx2term.json +1 -0
  12. interpro_binding_site/basic/plot_0.png +3 -0
  13. interpro_binding_site/basic/plot_1.png +3 -0
  14. interpro_binding_site/basic/plot_2.png +3 -0
  15. interpro_binding_site/consensus.joblib +3 -0
  16. interpro_binding_site/df_merge.tsv +1 -0
  17. interpro_binding_site/metrics.json +7 -0
  18. interpro_binding_site/paths.json +1 -0
  19. interpro_binding_site/result.tsv +8 -0
  20. interpro_binding_site/selections.json +1 -0
  21. interpro_conserved_site/advanced/idx2term.json +1 -0
  22. interpro_conserved_site/basic/idx2term.json +1 -0
  23. interpro_conserved_site/basic/plot_0.png +3 -0
  24. interpro_conserved_site/basic/plot_1.png +3 -0
  25. interpro_conserved_site/basic/plot_2.png +3 -0
  26. interpro_conserved_site/basic/plot_3.png +3 -0
  27. interpro_conserved_site/basic/plot_4.png +3 -0
  28. interpro_conserved_site/basic/plot_5.png +3 -0
  29. interpro_conserved_site/basic/plot_6.png +3 -0
  30. interpro_conserved_site/basic/plot_7.png +3 -0
  31. interpro_conserved_site/consensus.joblib +3 -0
  32. interpro_conserved_site/df_merge.tsv +2 -0
  33. interpro_conserved_site/metrics.json +7 -0
  34. interpro_conserved_site/paths.json +1 -0
  35. interpro_conserved_site/result.tsv +35 -0
  36. interpro_conserved_site/selections.json +1 -0
  37. interpro_domain/advanced/idx2term.json +1 -0
  38. interpro_domain/basic/idx2term.json +1 -0
  39. interpro_domain/basic/plot_0.png +3 -0
  40. interpro_domain/basic/plot_1.png +3 -0
  41. interpro_domain/basic/plot_10.png +3 -0
  42. interpro_domain/basic/plot_11.png +3 -0
  43. interpro_domain/basic/plot_12.png +3 -0
  44. interpro_domain/basic/plot_13.png +3 -0
  45. interpro_domain/basic/plot_14.png +3 -0
  46. interpro_domain/basic/plot_15.png +3 -0
  47. interpro_domain/basic/plot_16.png +3 -0
  48. interpro_domain/basic/plot_17.png +3 -0
  49. interpro_domain/basic/plot_18.png +3 -0
  50. interpro_domain/basic/plot_19.png +3 -0
interpro_active_site/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_active_site/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Serine/threonine-protein kinase, active site [IPR008271]"}
interpro_active_site/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: 077b31d298f319168880d4bb9862d81a42c569e5a201628a3a9ee163cbfa6bba
  • Pointer size: 131 Bytes
  • Size of remote file: 151 kB
interpro_active_site/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
2
+ oid sha256:d9d1a90858eb2dc568699850ea02b592ffd77ca2fae76448b533aa657d5cfdce
3
+ size 78192
interpro_active_site/df_merge.tsv ADDED
@@ -0,0 +1 @@
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_active_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3447,
4
+ "annotations_size": 57,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.9649122807017543
7
+ }
interpro_active_site/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C048/C048_val_log2fc"}
interpro_active_site/result.tsv ADDED
@@ -0,0 +1,6 @@
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Serine/threonine-protein kinase, active site [IPR008271] 0.367217036401163 1.049711368843133 0.2938508351569571 0.999999997561641 0.6442114463056368 56 Q86Y07,Q86UE8,Q96SB4,P11802,P27361,P31751,P48729,P53350,Q13555,Q96RG2,Q99986,P10398,Q9H4A3,Q7L7X3,P54646 15
3
+ Peptidase family C14A, His active site [IPR016129] 0.6995065877265565 0.8937330835891429 0.3714647197835181 0.9999999999968028 0.7301203112986391 3 P42574 1
4
+ Peptidase family C14A, cysteine active site [IPR033139] 0.6995065877265565 0.8937330835891429 0.3714647197835181 0.9999999999968028 0.7301203112986391 3 P42574 1
5
+ Ribonucleotide reductase small subunit, acitve site [IPR030475] 0.7869375907111735 0.5043993403849801 0.613980781481327 1.0 0.9007751439116172 2 Q7LG56 1
6
+ Ubiquitin-activating enzyme E1, Cys active site [IPR033127] 0.3101045296167289 0.0554243041485805 0.9558004336829052 1.0 0.9885172358617276 3 Q9UBT2,P22314 2
interpro_active_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase, active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CASP7", "CASP8", "CDK1", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK8", "CDK9", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EGFR", "EIF2AK2", "EPHA2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "JAK1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR1", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK1", "NEK9", "NME1", "NME2", "NME3", "OXCT1", "OXSM", "PAK2", "PASK", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN9", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYK2", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["AKT2", "ARAF", "CAMK2G", "CASP3", "CDK4", "CSNK1A1", "MAPK3", "PASK", "PLK1", "PRKAA2", "RRM2B", "SRPK1", "TAOK1", "TLK2", "UBA1", "UBA2", "VRK1", "VRK2", "WNK1"]}
interpro_binding_site/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_binding_site/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "IQ motif, EF-hand binding site [IPR000048]", "1": "Protein kinase, ATP binding site [IPR017441]", "2": "EF-Hand 1, calcium-binding site [IPR018247]"}
interpro_binding_site/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: cc6758343e9da7689ebc73cc0e738d937c00934d4b5f86b87b7ad406c648affa
  • Pointer size: 131 Bytes
  • Size of remote file: 136 kB
interpro_binding_site/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: f35457827ae61a150add4012e8adcb82dfc03db14b37af0917760a6a1a95398a
  • Pointer size: 131 Bytes
  • Size of remote file: 153 kB
interpro_binding_site/basic/plot_2.png ADDED

Git LFS Details

  • SHA256: 9bc2269b3512823ea2c3c230482db8392ad87f52c965a97b97d6706229511e02
  • Pointer size: 131 Bytes
  • Size of remote file: 143 kB
interpro_binding_site/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
2
+ oid sha256:293a248108bcf68c52e61ab6bfea653c132ccf6a796f2b14afd3cc8ccdc8f107
3
+ size 76821
interpro_binding_site/df_merge.tsv ADDED
@@ -0,0 +1 @@
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
interpro_binding_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3447,
4
+ "annotations_size": 33,
5
+ "title": "Average number of proteins per term",
6
+ "value": 5.090909090909091
7
+ }
interpro_binding_site/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C048/C048_val_log2fc"}
interpro_binding_site/result.tsv ADDED
@@ -0,0 +1,8 @@
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Biotin-binding site [IPR001882] 0.6997038056596305 1.2426362096658827 0.2140019203434318 0.9996460768226269 0.5432051862182121 4 Q96RQ3 1
3
+ IQ motif, EF-hand binding site [IPR000048] 0.5417302979623249 1.1184561805531263 0.2633722114997392 0.9999583910038572 0.5432051862182121 15 Q13459,Q86VI3,Q15051,Q15386,P35580,O43795,P35579,O94832 8
4
+ Protein kinase, ATP binding site [IPR017441] 0.3287742757689667 0.9038530741603672 0.3660733145608872 0.9999997067161684 0.7106129047358399 59 O95747,Q86UE8,Q96SB4,P11802,P27361,P31751,P48729,P53350,Q13555,Q96RG2,Q99986,P10398,P41240,Q7L7X3,P54646 15
5
+ EF-Hand 1, calcium-binding site [IPR018247] 0.3600959466933727 0.3874035822614333 0.6984574521982585 1.0 0.975862844074662 39 O43852,P80303,Q9Y680,Q96AY3,Q14257,Q02818 6
6
+ Beta tubulin, autoregulation binding site [IPR013838] 0.3627055749596196 0.2038660351051739 0.8384581877055686 1.0 0.975862844074662 6 Q9BUF5,P04350 2
7
+ Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798] 0.473730043541358 0.0483391664067248 0.9614459407441702 1.0 0.975862844074662 2 P34897 1
8
+ Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349] 0.4478955007256825 0.0423551049346769 0.966215617279881 1.0 0.975862844074662 2 Q9UQ80 1
interpro_binding_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Aryldialkylphosphatase, zinc-binding site [IPR017947]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APEX2", "APOBEC3C", "ARAF", "ARG2", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK8", "CDK9", "CEP97", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "EGFR", "EHD1", "EHD4", "EIF2AK2", "EPHA2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "JAK1", "LETM1", "LYN", "MACF1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO9B", "NEK1", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PASK", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRKCSH", "PSAT1", "PTER", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK1", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TYK2", "UBE3C", "ULK3", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["AKT2", "ARAF", "CALU", "CAMK2G", "CDK4", "CSK", "CSNK1A1", "FKBP10", "FKBP7", "IQCB1", "IQGAP3", "MAPK3", "MCCC1", "MYH10", "MYH9", "MYO1B", "MYO1D", "MYO9B", "NUCB1", "NUCB2", "OXSR1", "PA2G4", "PASK", "PLK1", "PRKAA2", "RCN2", "SHMT2", "SRPK1", "TAOK1", "TLK2", "TUBB4A", "TUBB6", "UBE3C", "VRK1"]}
interpro_conserved_site/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_conserved_site/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "Bromodomain, conserved site [IPR018359]", "1": "Kinesin motor domain, conserved site [IPR019821]", "2": "Ubiquitin specific protease, conserved site [IPR018200]", "3": "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "4": "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "5": "WD40 repeat, conserved site [IPR019775]", "6": "Tr-type G domain, conserved site [IPR031157]", "7": "Actinin-type actin-binding domain, conserved site [IPR001589]"}
interpro_conserved_site/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: e12e8031b9824b6c6babac3dec55c2be91bc6173afaf85bb1681d79ba2eec710
  • Pointer size: 131 Bytes
  • Size of remote file: 138 kB
interpro_conserved_site/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: ae888000ff2ec199918d7604dea55c41b3fd350d0e57b32b76abfc527a39def4
  • Pointer size: 131 Bytes
  • Size of remote file: 150 kB
interpro_conserved_site/basic/plot_2.png ADDED

Git LFS Details

  • SHA256: 190f69cc905aae82484c039907b87a7db3bf979d8330be00406a861288e6ad61
  • Pointer size: 131 Bytes
  • Size of remote file: 154 kB
interpro_conserved_site/basic/plot_3.png ADDED

Git LFS Details

  • SHA256: b760329193b1e1d2510337f7d64ab7075d88a0d316b7f1adf20b153e9fdf2f04
  • Pointer size: 131 Bytes
  • Size of remote file: 157 kB
interpro_conserved_site/basic/plot_4.png ADDED

Git LFS Details

  • SHA256: c6a79a44e04c8234d18c1f64c467f1c42b4c71a6e47c083a2a61a87ba82abe62
  • Pointer size: 131 Bytes
  • Size of remote file: 154 kB
interpro_conserved_site/basic/plot_5.png ADDED

Git LFS Details

  • SHA256: 1cc2bb286caecde959d363c4be10c162d84f0daed9bb2763bd56ca6844a2274c
  • Pointer size: 131 Bytes
  • Size of remote file: 169 kB
interpro_conserved_site/basic/plot_6.png ADDED

Git LFS Details

  • SHA256: 8f3f2850c908b4aee1138b97a7cb18a1a270fc5ddbfab0bfa2a20b5f8eaf6400
  • Pointer size: 131 Bytes
  • Size of remote file: 150 kB
interpro_conserved_site/basic/plot_7.png ADDED

Git LFS Details

  • SHA256: c611bd2499898f0b5d18611ba94efb81856ed8602aec6e4d6558730395f0d58e
  • Pointer size: 131 Bytes
  • Size of remote file: 155 kB
interpro_conserved_site/consensus.joblib ADDED
@@ -0,0 +1,3 @@
 
 
 
 
1
+ version https://git-lfs.github.com/spec/v1
2
+ oid sha256:92e1e3900df7844d5132f6d0b61f0c60613d3056b615a3a8434b8646416f7a5d
3
+ size 92952
interpro_conserved_site/df_merge.tsv ADDED
@@ -0,0 +1,2 @@
 
 
 
1
+ term overlap setsize score pval overlap_mean setsize_mean score_mean pval_mean overlap_std setsize_std score_std pval_std pval_hit pval_50 pval_100 pval_250 pval_500
2
+ Proteasome beta-type subunit, conserved site [IPR016050] 2 8 2.216671489914591 0.0266455483844816 3.7135922330097086 7.970873786407767 1.4913184573846054 0.1902243906475925 1.515457478026574 0.1681602725795027 1.0170822776023185 0.2455850375425174 1.0 0.0009534063593398 0.0039135152062846 0.0015031185668187 0.0106255777102749
interpro_conserved_site/metrics.json ADDED
@@ -0,0 +1,7 @@
 
 
 
 
 
 
 
 
1
+ {
2
+ "type_of_task": "ranksum",
3
+ "signature_size": 3447,
4
+ "annotations_size": 288,
5
+ "title": "Average number of proteins per term",
6
+ "value": 2.736111111111111
7
+ }
interpro_conserved_site/paths.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C048/C048_val_log2fc"}
interpro_conserved_site/result.tsv ADDED
@@ -0,0 +1,35 @@
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
1
+ Term es nes pval sidak fdr geneset_size leading_edge leading_edge_size
2
+ Proteasome beta-type subunit, conserved site [IPR016050] 0.8104033962606215 2.216671489914591 0.0266455483844816 0.9995811547417528 0.2883834288400348 8 P49721,P28072 2
3
+ Thioredoxin, conserved site [IPR017937] 0.648732250605208 1.6424517069633071 0.1004964266324961 0.9999999999999434 0.4373413328553885 10 P07237,O43396,O95881 3
4
+ D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753] 0.7050711704119336 1.263797088095432 0.2063028666271269 1.0 0.6675868043664333 4 O43175 1
5
+ Phosphatidylinositol 3/4-kinase, conserved site [IPR018936] 0.6226998408129621 1.2541910498950954 0.2097725722098589 1.0 0.6679515105982609 7 P42345,P78527,Q9UBF8,P42356 4
6
+ Intermediate filament protein, conserved site [IPR018039] 0.5874657003639722 1.2156675440905105 0.2241115926103938 1.0 0.6940229964708969 8 P07197,Q16352,P07196 3
7
+ Haem oxygenase conserved site [IPR018207] 0.982293178519594 1.1172940657124328 0.2638686119838995 1.0 0.7057857876969713 2 P09601 1
8
+ Ras GTPase-activating protein, conserved site [IPR023152] 0.6520816369542948 1.0555678421221648 0.2911656993000606 1.0 0.7057857876969713 4 Q86VI3 1
9
+ Bromodomain, conserved site [IPR018359] 0.5040377120983597 0.8330326378096459 0.404826322446068 1.0 0.8165239594008179 8 P25440,Q86U86,P51532,Q8WWQ0,Q9UIG0 5
10
+ Kinesin motor domain, conserved site [IPR019821] 0.4776033476107191 0.7992818485179538 0.4241270015145861 1.0 0.8424039754220746 13 O00139,Q02241,O95235,Q15058,Q9BW19 5
11
+ DnaJ domain, conserved site [IPR018253] 0.4670469034013478 0.7542778860167297 0.4506823781371345 1.0 0.8595796351224817 11 Q9Y2G8 1
12
+ Dynamin, GTPase region, conserved site [IPR019762] 0.8267053701015952 0.6172260520613895 0.5370856342926409 1.0 0.9431747724163452 2 O00429 1
13
+ Ubiquitin specific protease, conserved site [IPR018200] 0.4345272849967594 0.5908989559538121 0.5545881255837946 1.0 0.9529051208892524 15 O94782,Q8NB14,Q93009,P51784,Q9UPU5,Q93008,Q96K76,Q86UV5 8
14
+ Chromo domain, conserved site [IPR023779] 0.4242529921318733 0.3765307645185292 0.7065223486236452 1.0 1.0 6 O14646,Q13185 2
15
+ Ribosomal protein S2, conserved site [IPR018130] 0.7248185776487636 0.3483901385393752 0.7275472075091556 1.0 1.0 2 Q9Y399 1
16
+ DNA-directed DNA polymerase, family B, conserved site [IPR017964] 0.6563134978229279 0.2123516588135734 0.8318326963624221 1.0 1.0 2 P28340 1
17
+ Ribosomal protein L3, conserved site [IPR019926] 0.6560232220609542 0.2118651811948164 0.832212215317456 1.0 1.0 2 P39023 1
18
+ Tubulin, conserved site [IPR017975] 0.3627055749596196 0.2038660351051739 0.8384581877055686 1.0 1.0 6 Q9BUF5,P04350 2
19
+ DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464] 0.3348807217022327 0.1882636747730447 0.8506699594879734 1.0 1.0 17 Q9UNY4,Q7L2E3,Q92620,Q08211,Q14562,O94762,Q14839,P18074 8
20
+ Guanylate kinase, conserved site [IPR020590] 0.3535563376745392 0.1828519096474583 0.8549142171564319 1.0 1.0 6 Q9NZW5,Q5TCQ9,O14936 3
21
+ Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412] 0.3236280266528843 0.1623927504628751 0.8709965793596912 1.0 1.0 14 Q5JPH6,P23381,Q15031,P26640,Q5ST30,Q9P2J5,P07814,Q5T160 8
22
+ IMP dehydrogenase / GMP reductase, conserved site [IPR015875] 0.5988388969520998 0.1313314465074203 0.8955131165085093 1.0 1.0 2 P12268 1
23
+ Oxysterol-binding protein, conserved site [IPR018494] 0.3252006157687367 0.1097178210625689 0.9126331665806936 1.0 1.0 5 P22059 1
24
+ Heat shock protein Hsp90, conserved site [IPR019805] 0.3895246963486011 0.1048175830710158 0.9165205576332338 1.0 1.0 3 P07900 1
25
+ WD40 repeat, conserved site [IPR019775] 0.2226591927585874 0.097731690759931 0.922145350420562 1.0 1.0 59 P43034,Q9NZJ0,P62873,Q8NFH4,Q8TEQ6,P63244,Q9UKB1 7
26
+ FERM conserved site [IPR019747] 0.2900635756420101 0.0950536770799502 0.9242721917435016 1.0 1.0 9 Q9HCM4,P35241,Q9Y2J2 3
27
+ DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514] 0.4853410740203131 0.0519168153351767 0.9585949756444904 1.0 1.0 2 O15160 1
28
+ Tr-type G domain, conserved site [IPR031157] 0.2670735251380484 0.0500235110767801 0.9601036526433556 1.0 1.0 6 P13639,P15170,P49411,Q96RP9,Q8N442 5
29
+ DNA topoisomerase, type IIA, conserved site [IPR018522] 0.4766328011610967 0.049176683313925 0.9607784927994624 1.0 1.0 2 P11388 1
30
+ Actinin-type actin-binding domain, conserved site [IPR001589] 0.2728739281745783 0.0469847471705172 0.9625253840973248 1.0 1.0 13 Q8WXH0,O43707,Q01082,P12814,P46939 5
31
+ Histidine triad, conserved site [IPR019808] 0.4197387518142185 0.0382556735880462 0.9694838322469008 1.0 1.0 2 Q9BX68 1
32
+ Polyamine biosynthesis domain, conserved site [IPR030373] 0.3399129172714017 0.0341243481944876 0.972777992737632 1.0 1.0 2 P19623 1
33
+ Fork head domain conserved site1 [IPR018122] 0.3155297532655958 0.0338499333948924 0.9729968176471512 1.0 1.0 2 Q01167 1
34
+ Fork head domain conserved site 2 [IPR030456] 0.3155297532655958 0.0338499333948924 0.9729968176471512 1.0 1.0 2 Q01167 1
35
+ Zinc finger, RING-type, conserved site [IPR017907] 0.2642633397164878 0.0216022152139349 0.982765266459865 1.0 1.0 19 Q99728,P38398,Q99590,P19474 4
interpro_conserved_site/selections.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "2-5-oligoadenylate synthetase, C-terminal conserved site [IPR006117]", "2-5-oligoadenylate synthetase, N-terminal conserved site [IPR043518]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein, copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific, conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kank N-terminal motif [IPR021939]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P, conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site [IPR018168]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABR", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ARRB2", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BARD1", "BAZ1A", "BAZ1B", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ6", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DTL", "DTYMK", "DUS2", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FBXW11", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXK2", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXA10", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "ING5", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "IVD", "KANK2", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAGI3", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRC2", "MRPL13", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NET1", "NF1", "NKTR", "NLE1", "NMT1", "NMT2", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSD3", "NSF", "NUBP2", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OAS3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBFA", "RCL1", "RDH13", "RDX", "RECQL5", "RELA", "RIDA", "RIOK2", "RNF114", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SH3RF1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX18", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAF5L", "TAP2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP34", "USP38", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VAV2", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR55", "WDR61", "WDR77", "WDR83", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ACTN1", "ACTN4", "BARD1", "BAZ1B", "BRCA1", "BRD2", "CASK", "CBX3", "CHD1", "CHD4", "DHX30", "DHX38", "DHX8", "DHX9", "DNAJC16", "DNM1L", "DTL", "EARS2", "EEF2", "EPB41L3", "EPB41L5", "EPRS", "ERCC2", "FBXW11", "FOXK2", "GEMIN5", "GFM1", "GNB1", "GSPT1", "GUF1", "HINT2", "HMOX1", "HSP90AA1", "IMPDH2", "INA", "IQGAP3", "KIF14", "KIF20A", "KIF23", "KIF2A", "KIFC1", "LARS", "LARS2", "MAGI3", "MPP6", "MRPS2", "MTOR", "NEFL", "NEFM", "NUP37", "OSBP", "P4HB", "PAFAH1B1", "PBRM1", "PHGDH", "PHIP", "PI4KA", "PI4KB", "POLD1", "POLR1C", "PRKDC", "PSMB2", "PSMB6", "RACK1", "RARS2", "RDX", "RECQL5", "RPL3", "SCAF11", "SMARCA4", "SPTBN1", "SRM", "SYNE2", "TOP2A", "TRIM21", "TTF2", "TUBB4A", "TUBB6", "TUFM", "TXNDC12", "TXNL1", "USP1", "USP11", "USP24", "USP38", "USP47", "USP48", "USP7", "USP9X", "UTRN", "VARS1", "VARS2", "WARS"]}
interpro_domain/advanced/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {}
interpro_domain/basic/idx2term.json ADDED
@@ -0,0 +1 @@
 
 
1
+ {"0": "FKBP-type peptidyl-prolyl cis-trans isomerase domain [IPR001179]", "1": "Zinc finger, RanBP2-type [IPR001876]", "2": "BRCT domain [IPR001357]", "3": "Helicase-associated domain [IPR007502]", "4": "Domain of unknown function DUF1605 [IPR011709]", "5": "TOG domain [IPR034085]", "6": "High mobility group box domain [IPR009071]", "7": "K Homology domain [IPR004087]", "8": "K Homology domain, type 1 [IPR004088]", "9": "Forkhead-associated (FHA) domain [IPR000253]", "10": "Thioredoxin domain [IPR013766]", "11": "Kinesin motor domain [IPR001752]", "12": "Myosin head, motor domain [IPR001609]", "13": "Ubiquitin specific protease domain [IPR028889]", "14": "Chromo/chromo shadow domain [IPR000953]", "15": "Protein kinase domain [IPR000719]", "16": "B30.2/SPRY domain [IPR001870]", "17": "SPRY domain [IPR003877]", "18": "Peptidase C19, ubiquitin carboxyl-terminal hydrolase [IPR001394]", "19": "SNF2, N-terminal [IPR000330]", "20": "Helicase, C-terminal [IPR001650]", "21": "Helicase superfamily 1/2, ATP-binding domain [IPR014001]", "22": "MIF4G-like, type 3 [IPR003890]", "23": "SANT/Myb domain [IPR001005]", "24": "Zinc finger C2H2-type [IPR013087]", "25": "G-patch domain [IPR000467]", "26": "Guanylate kinase/L-type calcium channel beta subunit [IPR008145]", "27": "Guanylate kinase-like domain [IPR008144]", "28": "Aminoacyl-tRNA synthetase, class II [IPR006195]", "29": "Aminoacyl-tRNA synthetase, class II (G/ P/ S/T) [IPR002314]", "30": "Importin-beta, N-terminal domain [IPR001494]", "31": "Translational (tr)-type GTP-binding domain [IPR000795]", "32": "MPN domain [IPR037518]"}
interpro_domain/basic/plot_0.png ADDED

Git LFS Details

  • SHA256: 91d0b87313b327a57ad9a5c92b404f4e603797ae4555881550e405d9658307b7
  • Pointer size: 131 Bytes
  • Size of remote file: 139 kB
interpro_domain/basic/plot_1.png ADDED

Git LFS Details

  • SHA256: 413ac65549a7392f8135864beb6f8f49ea583a8b81d5da95105965b8c3f4b580
  • Pointer size: 131 Bytes
  • Size of remote file: 134 kB
interpro_domain/basic/plot_10.png ADDED

Git LFS Details

  • SHA256: b733fb826a0bc6531644970ba8ddb8d3700c4441f5419a9c326405ece47afbf8
  • Pointer size: 131 Bytes
  • Size of remote file: 143 kB
interpro_domain/basic/plot_11.png ADDED

Git LFS Details

  • SHA256: 3b269a3c24c7afe244922ddbbcb5d8ef50274c8c37a096117a521b28ff023651
  • Pointer size: 131 Bytes
  • Size of remote file: 144 kB
interpro_domain/basic/plot_12.png ADDED

Git LFS Details

  • SHA256: 23eafb951cbbaa8b2196259cf4f997fae70878f4b3b24056d0a0b821ae03fd7b
  • Pointer size: 131 Bytes
  • Size of remote file: 141 kB
interpro_domain/basic/plot_13.png ADDED

Git LFS Details

  • SHA256: 6267c8aeb596c2430e85a975178712b0c7b6571034726627fded7d0201a8404f
  • Pointer size: 131 Bytes
  • Size of remote file: 152 kB
interpro_domain/basic/plot_14.png ADDED

Git LFS Details

  • SHA256: f24d40b7c9ca162ddcb51e520827940abad7c68a8a6ea172adbb6a39a85cbe81
  • Pointer size: 131 Bytes
  • Size of remote file: 152 kB
interpro_domain/basic/plot_15.png ADDED

Git LFS Details

  • SHA256: 777edd99606f021bdf98e65ca63d3c89b57fdadb8aab92839cde8d4137e139ba
  • Pointer size: 131 Bytes
  • Size of remote file: 151 kB
interpro_domain/basic/plot_16.png ADDED

Git LFS Details

  • SHA256: 154049829feaa89812a2a3f9c9b5ac4547d91c98b7c309451e71c6bdfc30118a
  • Pointer size: 131 Bytes
  • Size of remote file: 147 kB
interpro_domain/basic/plot_17.png ADDED

Git LFS Details

  • SHA256: 9ee9bc9652c3f2c7c8ca68ec6ba5d9694c3cda802d0a6de226731bfbb64d6c17
  • Pointer size: 131 Bytes
  • Size of remote file: 143 kB
interpro_domain/basic/plot_18.png ADDED

Git LFS Details

  • SHA256: 6c3ad92b01757ff256cefa4eda7bb81e719f6e2612d8346857ca737f6695fd03
  • Pointer size: 131 Bytes
  • Size of remote file: 156 kB
interpro_domain/basic/plot_19.png ADDED

Git LFS Details

  • SHA256: 547de93cb029ce0ef62c93448f0be6954f004345277fc23f99cd87ad35a74718
  • Pointer size: 131 Bytes
  • Size of remote file: 147 kB