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interpro_active_site/advanced/idx2term.json

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+{}

interpro_active_site/basic/idx2term.json

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+{}

interpro_active_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:ddc3625db05fb0369c42cd30968ed584e741168bcb3f4c2c9a22856486df3db9
+size 78753

interpro_active_site/df_merge.tsv

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+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500

interpro_active_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3447,
+    "annotations_size": 57,
+    "title": "Average number of proteins per term",
+    "value": 2.9649122807017543
+}

interpro_active_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_active_site/fragment/C049/C049_val_log2fc"}

interpro_active_site/result.tsv

@@ -0,0 +1,5 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Histidine acid phosphatase active site [IPR033379]	0.836284470246753	0.7632520197997414	0.4453131105362324	0.9999999999999974	0.7531544188319728	2	Q9NPH0	1
+Ribonucleotide reductase small subunit, acitve site [IPR030475]	0.7111756168359911	0.3787786864421485	0.704852215862535	1.0	0.8370120063367603	2	Q7LG56	1
+Ubiquitin-activating enzyme E1, Cys active site [IPR033127]	0.5861960856871175	0.3020415512116208	0.7626203879719715	1.0	0.8530962575512934	3	Q9UBT2	1
+Glycosyl hydrolases family 31, active site [IPR030458]	0.6748911465892563	0.290566170559055	0.7713831362050625	1.0	0.8530962575512934	2	P10253	1

interpro_active_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["ATP-citrate lyase/succinyl-CoA ligase, active site [IPR017440]", "ATP:guanido phosphotransferase active site [IPR022415]", "ATPase, alpha/beta subunit, nucleotide-binding domain, active site [IPR020003]", "Adenosine/AMP deaminase active site [IPR006650]", "Adenylosuccinate synthase,  active site [IPR033128]", "Beta-ketoacyl synthase, active site [IPR018201]", "Citrate synthase active site [IPR019810]", "ClpP, Ser active site [IPR018215]", "ClpP, histidine active site [IPR033135]", "Coenzyme A transferase active site [IPR004164]", "Cysteine peptidase, asparagine active site [IPR025661]", "Cysteine peptidase, cysteine active site [IPR000169]", "Cysteine peptidase, histidine active site [IPR025660]", "DNA methylase, C-5 cytosine-specific, active site [IPR018117]", "DNA topoisomerase I, active site [IPR018521]", "Ferrochelatase, active site [IPR019772]", "Glucose-6-phosphate dehydrogenase, active site [IPR019796]", "Glutaredoxin active site [IPR011767]", "Glyceraldehyde 3-phosphate dehydrogenase, active site [IPR020830]", "Glycosyl hydrolases family 31, active site [IPR030458]", "Histidine acid phosphatase active site [IPR033379]", "Hydroxymethylglutaryl-CoA lyase, active site [IPR000138]", "Hydroxymethylglutaryl-coenzyme A synthase, active site [IPR000590]", "L-lactate dehydrogenase, active site [IPR018177]", "Leu/Phe/Val dehydrogenases active site [IPR033524]", "Lipase, GDXG, putative serine active site [IPR033140]", "Malate dehydrogenase, active site [IPR001252]", "Nucleoside diphosphate kinase, active site [IPR023005]", "Orotidine 5'-phosphate decarboxylase, active site [IPR018089]", "Peptidase S16, active site [IPR008268]", "Peptidase S26A, signal peptidase I, serine active site [IPR019756]", "Peptidase S8, subtilisin, His-active site [IPR022398]", "Peptidase S8, subtilisin, Ser-active site [IPR023828]", "Peptidase S9, serine active site [IPR002471]", "Peptidase family C14A, His active site [IPR016129]", "Peptidase family C14A, cysteine active site [IPR033139]", "Phosphoglycerate/bisphosphoglycerate mutase, active site [IPR001345]", "Phosphoribosylglycinamide formyltransferase, active site [IPR001555]", "Protein-tyrosine phosphatase, active site [IPR016130]", "Pyridine nucleotide-disulphide oxidoreductase, class I, active site [IPR012999]", "Pyruvate kinase, active site [IPR018209]", "Ribonuclease T2, His active site 1 [IPR018188]", "Ribonuclease T2, His active site 2 [IPR033130]", "Ribonucleotide reductase small subunit, acitve site [IPR030475]", "Serine carboxypeptidase, serine active site [IPR018202]", "Serine carboxypeptidases, histidine active site [IPR033124]", "Serine/threonine-protein kinase, active site [IPR008271]", "Thermonuclease active site [IPR002071]", "Thiolase, active site [IPR020610]", "Thiolase, acyl-enzyme intermediate active site [IPR020615]", "Thymidylate synthase, active site [IPR020940]", "Transaldolase, active site [IPR018225]", "Triosephosphate isomerase, active site [IPR020861]", "Tyrosine-protein kinase, active site [IPR008266]", "Ubiquitin-activating enzyme E1, Cys active site [IPR033127]", "Ubiquitin-conjugating enzyme, active site [IPR023313]", "Uracil-DNA glycosylase, active site [IPR018085]"], "available_proteins": ["ACAA1", "ACAA2", "ACAT1", "ACAT2", "ACLY", "ACP2", "ACP6", "ADA", "ADSS", "AKT2", "AMPD2", "APEH", "ARAF", "ATP5A1", "ATP5B", "ATP6V1A", "ATP6V1B2", "AURKA", "BLMH", "BUB1", "CAMK2G", "CAPN1", "CAPN2", "CASP3", "CASP7", "CASP8", "CDK1", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK8", "CDK9", "CHUK", "CKB", "CKMT1A*", "CLPP", "CPVL", "CS", "CSK", "CSNK1A1", "CSNK2A2", "CTSA", "CTSC", "DLD", "DNMT1", "DUSP3", "EGFR", "EIF2AK2", "EPHA2", "EPHA7", "FASN", "FECH", "G6PD", "GAA", "GAK", "GANAB", "GAPDH", "GART", "GLRX", "GLUD1", "GSR", "HADHB", "HMGCL", "HMGCS1", "IKBKB", "JAK1", "LDHA", "LDHB", "LONP1", "LYN", "MAP2K1", "MAPK1", "MAPK3", "MAPKAPK3", "MARK2", "MASTL", "MDH1", "MDH2", "MTMR1", "MTMR14", "MTMR2", "MTMR6", "NCEH1", "NEK1", "NEK9", "NME1", "NME2", "NME3", "OXCT1", "OXSM", "PAK2", "PASK", "PBK", "PGAM1", "PIK3R4", "PKM", "PKMYT1", "PKN1", "PKN2", "PLK1", "PREP", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRPF4B", "PTK7", "PTPN1", "PTPN11", "PTPN9", "PTPRF", "RIPK1", "RNASET2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "RRM2", "RRM2B", "SCP2", "SCPEP1", "SEC11A", "SLK", "SND1", "SRPK1", "SRPK2", "SUCLG1", "TALDO1", "TAOK1", "TIGAR", "TLK2", "TOP1", "TPI1", "TPP2", "TTK", "TXNRD1", "TYK2", "TYMS", "UBA1", "UBA2", "UBA3", "UBE2G2", "UBE2K", "UBE2L3", "UBE2M", "UBE2S", "ULK3", "UMPS", "UNG", "VRK1", "VRK2", "WNK1", "YES1"], "leading_proteins": ["ACP6", "GAA", "RRM2B", "UBA2"]}

interpro_binding_site/advanced/idx2term.json

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+{"0": "Beta tubulin, autoregulation binding site [IPR013838]"}

interpro_binding_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Beta tubulin, autoregulation binding site [IPR013838]", "1": "EF-Hand 1, calcium-binding site [IPR018247]"}

interpro_binding_site/consensus.joblib

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+version https://git-lfs.github.com/spec/v1
+oid sha256:22ba23bb04829c592b5cc5a09e81118d52a5ecbf84f4504761150a076b75fea6
+size 78431

interpro_binding_site/df_merge.tsv

@@ -0,0 +1,2 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Beta tubulin, autoregulation binding site [IPR013838]	5	6	2.686227661162481	0.0072263831966969	3.5533980582524274	5.54126213592233	0.5823511994709325	0.3808337519133083	1.5578062452886454	0.9632803779920796	1.1906256051626651	0.3058955364405814	1.7266928721032302e-10	8.064461453409737e-06	8.588340643785131e-09	1.4325000410530922e-08	9.198278535610612e-07

interpro_binding_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3447,
+    "annotations_size": 33,
+    "title": "Average number of proteins per term",
+    "value": 5.090909090909091
+}

interpro_binding_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_binding_site/fragment/C049/C049_val_log2fc"}

interpro_binding_site/result.tsv

@@ -0,0 +1,4 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Beta tubulin, autoregulation binding site [IPR013838]	0.9703574542284192	2.686227661162481	0.0072263831966969	0.2128500061072071	0.2384706454910008	6	Q9BVA1,P07437,P68371,P04350,Q13885	5
+EF-Hand 1, calcium-binding site [IPR018247]	0.4399818660623597	1.2188140464815869	0.2229147789370382	0.999757078792304	0.6687443368111148	39	Q14257,Q02818,P41208,O95202,Q6NUK1,Q9NWM8,Q9BRK5,P80303,Q9Y680	9
+APOBEC/CMP deaminase, zinc-binding [IPR016192]	0.351233671988383	0.0301592168384935	0.9759400739719511	1.0	1.0	2	Q9NRW3	1

interpro_binding_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["2-oxo acid dehydrogenase, lipoyl-binding site [IPR003016]", "2Fe-2S ferredoxin, iron-sulphur binding site [IPR006058]", "6-phosphogluconate-binding site [IPR006184]", "AP endonuclease 1, binding site [IPR020847]", "APOBEC/CMP deaminase, zinc-binding [IPR016192]", "Aconitase family, 4Fe-4S cluster binding site [IPR018136]", "Adenylosuccinate synthase, GTP-binding site [IPR018220]", "Aminotransferase class-V, pyridoxal-phosphate binding site [IPR020578]", "Aminotransferase, class-II, pyridoxal-phosphate binding site [IPR001917]", "Aminotransferases, class-I, pyridoxal-phosphate-binding site [IPR004838]", "Aryldialkylphosphatase, zinc-binding site [IPR017947]", "Beta tubulin, autoregulation binding site [IPR013838]", "Biotin-binding site [IPR001882]", "Coenzyme A transferase binding site [IPR004163]", "Copper centre Cu(A) [IPR001505]", "Cytochrome b5, heme-binding site [IPR018506]", "Cytochrome c oxidase, subunit Vb, zinc binding site [IPR020893]", "EF-Hand 1, calcium-binding site [IPR018247]", "Fumarate reductase/succinate dehydrogenase, FAD-binding site [IPR003952]", "Hexokinase, binding site [IPR019807]", "IQ motif, EF-hand binding site [IPR000048]", "Inositol monophosphatase, metal-binding site [IPR020583]", "Manganese/iron superoxide dismutase, binding site [IPR019833]", "PPM-type phosphatase, divalent cation binding [IPR000222]", "Peptidase M16, zinc-binding site [IPR001431]", "Peptidase M24A, methionine aminopeptidase, subfamily 2, binding site [IPR018349]", "Porphobilinogen deaminase, dipyrromethane cofactor binding site [IPR022419]", "Protein kinase, ATP binding site [IPR017441]", "RNA polymerases, subunit N, zinc binding site [IPR020789]", "Serine hydroxymethyltransferase, pyridoxal phosphate binding site [IPR019798]", "Sigma-54 interaction domain, ATP-binding site 1 [IPR025662]", "Transketolase binding site [IPR020826]", "Ureohydrolase, manganese-binding site [IPR020855]"], "available_proteins": ["ACACA", "ACO1", "ACO2", "ACTN1", "ACTN4", "ADSS", "AKT2", "APEX1", "APEX2", "APOBEC3C", "ARAF", "ARG2", "AURKA", "BPNT1", "BUB1", "CALM3", "CALU", "CAMK2G", "CAPN1", "CAPN2", "CAPNS1", "CDK1", "CDK16", "CDK2", "CDK4", "CDK5", "CDK6", "CDK8", "CDK9", "CEP97", "CETN2", "CHUK", "COX2", "COX5B", "CSK", "CSNK1A1", "CSNK2A2", "CYB5B", "DBT", "DCTD", "DLAT", "DLST", "EGFR", "EHD1", "EHD4", "EIF2AK2", "EPHA2", "EPHA7", "EPS15", "EPS15L1", "FKBP10", "FKBP14", "FKBP7", "FKBP9", "GCAT", "GOT1", "GOT2", "GPD2", "HK1", "HK2", "HMBS", "IDE", "ILKAP", "IQCB1", "IQGAP1", "IQGAP2", "IQGAP3", "JAK1", "LETM1", "LYN", "MACF1", "MAP2K1", "MAPK1", "MAPK14", "MAPK3", "MAPKAPK3", "MARK2", "MCCC1", "METAP2", "MICU1", "MYH10", "MYH14", "MYH9", "MYO18A", "MYO1B", "MYO1C", "MYO1D", "MYO1E", "MYO9B", "NEK1", "NFS1", "NRDC", "NUCB1", "NUCB2", "OXCT1", "OXSR1", "PA2G4", "PAK2", "PAK4", "PASK", "PC", "PCCA", "PDCD6", "PDHX", "PEF1", "PGD", "PKMYT1", "PKN1", "PKN2", "PLCG1", "PLK1", "PLS1", "PLS3", "PMPCA", "PMPCB", "POLR2L", "PPM1G", "PRKAA1", "PRKAA2", "PRKACA", "PRKCA", "PRKCD", "PRKCSH", "PSAT1", "PTER", "RAB18", "RCN1", "RCN2", "REPS1", "RHOT1", "RHOT2", "ROCK1", "ROCK2", "RPS6KA1", "RPS6KA3", "S100A11", "SDF4", "SDHA", "SDHB", "SHMT1", "SHMT2", "SLC25A12", "SLC25A24", "SLK", "SOD2", "SPTAN1", "SPTLC2", "SRI", "SRPK1", "SRPK2", "STK26", "STK4", "TAOK1", "TKT", "TLK2", "TTK", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TYK2", "UBE3C", "ULK3", "UQCRC2", "VRK1", "YES1"], "leading_proteins": ["APOBEC3C", "CETN2", "FKBP14", "FKBP7", "LETM1", "NUCB1", "NUCB2", "RCN2", "SDF4", "SLC25A24", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B"]}

interpro_conserved_site/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin, conserved site [IPR017975]"}

interpro_conserved_site/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin, conserved site [IPR017975]", "1": "14-3-3 protein, conserved site [IPR023409]"}

interpro_conserved_site/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:0905994265d1495d2b04d30c5ee81edc21a2ad6d2a4d73ad5bc04c168e9d697d
+size 89981

interpro_conserved_site/df_merge.tsv

@@ -0,0 +1,4 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Tubulin, conserved site [IPR017975]	5	6	2.686227661162481	0.0072263831966969	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	3.5046047927792675e-08	7.603990755252932e-05	5.456750888757529e-07	2.6381727410940915e-06	0.0001398239466262
+Syntaxin/epimorphin, conserved site [IPR006012]	3	5	2.0223462383515827	0.043140594933259	2.592233009708738	5.847087378640777	0.9961908981999794	0.2839139128702306	1.4759357288864456	1.4239341993278547	1.138258151200134	0.2914162845337057	0.1405117947503903	1.0	0.1169218221283287	0.2712176839291556	0.0027224486194276
+Thioredoxin, conserved site [IPR017937]	4	10	1.9619958411488996	0.0497629684470155	3.905339805825242	10.99514563106796	0.4926509002179139	0.4659055513701703	2.3960466288532025	1.0404329420711995	1.0069927416530815	0.3218319873274993	0.0110357163015148	1.0	0.0075668597133861	0.0040998381065295	0.0274553466771513

interpro_conserved_site/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3447,
+    "annotations_size": 288,
+    "title": "Average number of proteins per term",
+    "value": 2.736111111111111
+}

interpro_conserved_site/paths.json

@@ -0,0 +1 @@
+{"results_path": "results/proteins/hek293t_core/interpro_conserved_site/fragment/C049/C049_val_log2fc"}

interpro_conserved_site/result.tsv

@@ -0,0 +1,27 @@
+Term	es	nes	pval	sidak	fdr	geneset_size	leading_edge	leading_edge_size
+Tubulin, conserved site [IPR017975]	0.9703574542284192	2.686227661162481	0.0072263831966969	0.8761587225314005	0.4215216150806024	6	Q9BVA1,P07437,P68371,P04350,Q13885	5
+Syntaxin/epimorphin, conserved site [IPR006012]	0.8237749440854576	2.0223462383515827	0.043140594933259	0.9999969502697612	0.4215216150806024	5	Q13190,Q9P2W9,O60499	3
+Thioredoxin, conserved site [IPR017937]	0.7519440670821461	1.9619958411488991	0.0497629684470155	0.9999995873308936	0.4215216150806024	10	Q9H3N1,O95881,P07237,Q9H1E5	4
+Haem oxygenase conserved site [IPR018207]	0.9968069666182872	1.3507270940560707	0.1767828697952753	1.0	0.5996531979431062	2	P09601	1
+Sterol reductase, conserved site [IPR018083]	0.8858885017421461	1.3488243656805332	0.1773933864862997	1.0	0.5996531979431062	3	Q14739,O76062	2
+Mini-chromosome maintenance, conserved site [IPR018525]	0.6318449156700741	1.2230250036958878	0.2213202525515272	1.0	0.659272953535991	6	Q14566	1
+DNA mismatch repair, conserved site [IPR014762]	0.8952104499274307	0.9721914929502636	0.330955291933422	1.0	0.8009674292170214	2	Q86VD7	1
+Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]	0.513636049260942	0.7060109155580525	0.4801813493187741	1.0	0.9415590952590476	7	P42345,Q9UBF8	2
+ABC transporter-like, conserved site [IPR017871]	0.4736376501230153	0.6126979743859492	0.5400760621476772	1.0	0.9653513753525524	11	P08183,Q03519,P28288	3
+Short-chain dehydrogenase/reductase, conserved site [IPR020904]	0.4509794935354526	0.527104492824369	0.5981210269369084	1.0	0.9978947999046364	12	Q06136,Q53GQ0,Q8NBN7,Q9Y394	4
+Dynamin, GTPase region, conserved site [IPR019762]	0.7402031930333803	0.4580786098563307	0.6468959658345117	1.0	1.0	2	O00429	1
+Clathrin adaptor, mu subunit, conserved site [IPR018240]	0.6405629909053603	0.4549897533727494	0.6491166105265764	1.0	1.0	3	Q9BXS5	1
+HMG box A DNA-binding domain, conserved site [IPR017967]	0.6393728222996437	0.4513525719111022	0.6517354603324739	1.0	1.0	3	P26583,O15347	2
+Polyamine biosynthesis domain, conserved site [IPR030373]	0.7352685050798233	0.4440947443358787	0.6569740861085454	1.0	1.0	2	P19623	1
+DnaJ domain, conserved site [IPR018253]	0.4214988442020702	0.3629552225665888	0.7166383338195423	1.0	1.0	11	Q96KC8,Q9Y2G8	2
+Ras GTPase-activating protein, conserved site [IPR023152]	0.4905605576532185	0.3489247759203324	0.7271457842618922	1.0	1.0	4	P21359,Q86VI3,P46940	3
+Chaperonin TCP-1, conserved site [IPR002194]	0.4198369077681815	0.3163893036407649	0.7517070347619177	1.0	1.0	8	P78371,P49368	2
+Glycosyl hydrolases family 31, conserved site [IPR030459]	0.6748911465892563	0.290566170559055	0.7713831362050625	1.0	1.0	2	P10253	1
+Proteasome beta-type subunit, conserved site [IPR016050]	0.3986185828532754	0.2350961703038955	0.8141340910630106	1.0	1.0	8	P49721	1
+Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]	0.5528455284552878	0.2234704486756262	0.8231693801416582	1.0	1.0	3	Q16539,P27361	2
+Profilin conserved site [IPR027310]	0.4934687953555817	0.0549746928708691	0.9561586254584252	1.0	1.0	2	P35080	1
+GTP1/OBG, conserved site [IPR006074]	0.4824383164005741	0.0502195916567821	0.9599473993668544	1.0	1.0	2	P55039	1
+3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]	0.4801161103047831	0.0493129466145395	0.9606699021645976	1.0	1.0	2	P40939	1
+14-3-3 protein, conserved site [IPR023409]	0.3289741354257566	0.0357576922656829	0.9714755681568834	1.0	1.0	6	P27348,P31946,P61981,P63104,P62258	5
+Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]	0.3169668797210873	0.0314031850132936	0.9749480011321704	1.0	1.0	5	P52735,Q14155,Q7Z628,P11274	4
+Phosphofructokinase, conserved site [IPR015912]	0.3890824622531978	0.0253924232052202	0.9797419545673076	1.0	1.0	3	P08237,P17858	2

interpro_conserved_site/selections.json

@@ -0,0 +1 @@
+{"all_annotations": ["14-3-3 protein, conserved site [IPR023409]", "2-5-oligoadenylate synthetase, C-terminal  conserved site [IPR006117]", "2-5-oligoadenylate synthetase, N-terminal conserved site [IPR043518]", "3-hydroxyacyl-CoA dehydrogenase, conserved site [IPR006180]", "3-hydroxyisobutyrate dehydrogenase-related, conserved site [IPR002204]", "4Fe-4S ferredoxin, iron-sulphur binding, conserved site [IPR017900]", "ABC transporter-like, conserved site [IPR017871]", "AMP-binding, conserved site [IPR020845]", "AP endonuclease 1, conserved site [IPR020848]", "AT hook, DNA-binding motif [IPR017956]", "ATP synthase, F1 complex, gamma subunit conserved site [IPR023632]", "ATP-citrate lyase/succinyl-CoA ligase, conserved site [IPR033847]", "ATP-dependent RNA helicase DEAD-box, conserved site [IPR000629]", "ATPase, AAA-type, conserved site [IPR003960]", "ATPase, OSCP/delta subunit, conserved site [IPR020781]", "Acin1, RNSP1-SAP18 binding (RSB) motif [IPR032552]", "Actin, conserved site [IPR004001]", "Actin/actin-like conserved site [IPR020902]", "Actinin-type actin-binding domain, conserved site [IPR001589]", "Acyl-CoA dehydrogenase, conserved site [IPR006089]", "Acyl-CoA-binding protein, ACBP, conserved site [IPR022408]", "Adenylate kinase, conserved site [IPR033690]", "Alanine dehydrogenase/NAD(P) transhydrogenase, conserved site-1 [IPR008142]", "Alanine dehydrogenase/pyridine nucleotide transhydrogenase, conserved site-2 [IPR008143]", "Alcohol dehydrogenase, zinc-type, conserved site [IPR002328]", "Aldehyde dehydrogenase, cysteine active site [IPR016160]", "Aldehyde dehydrogenase, glutamic acid active site [IPR029510]", "Aldo/keto reductase, conserved site [IPR018170]", "Aldose 1-epimerase, conserved site [IPR018052]", "Alpha-D-phosphohexomutase, conserved site [IPR016066]", "Aminoacyl-tRNA synthetase, class I, conserved site [IPR001412]", "Aminotransferase, class IV, conserved site [IPR018300]", "Amyloidogenic glycoprotein,  copper-binding domain conserved site [IPR019744]", "Amyloidogenic glycoprotein, intracellular domain, conserved site [IPR019745]", "Annexin repeat, conserved site [IPR018252]", "Apoptosis regulator, Bcl-2, BH1 motif, conserved site [IPR020717]", "Apoptosis regulator, Bcl-2, BH2 motif, conserved site [IPR020726]", "Apoptosis regulator, Bcl-2, BH3 motif, conserved site [IPR020728]", "ArgE/DapE/ACY1/CPG2/YscS, conserved site [IPR001261]", "Arrestin, conserved site [IPR017864]", "BUD31/G10-related, conserved site [IPR018230]", "Bacterial Fmu (Sun)/eukaryotic nucleolar NOL1/Nop2p, conserved site [IPR018314]", "Band 7/stomatin-like, conserved site [IPR018080]", "Bromodomain, conserved site [IPR018359]", "C-type lectin, conserved site [IPR018378]", "CAMSAP, spectrin and Ca2+/calmodulin-binding region [IPR031372]", "CAP, conserved site, C-terminal [IPR028417]", "CAP, conserved site, N-terminal [IPR018106]", "CBX family C-terminal motif [IPR033773]", "Cadherin conserved site [IPR020894]", "Calreticulin/calnexin, conserved site [IPR018124]", "Carbohydrate/purine kinase, PfkB, conserved site [IPR002173]", "Chaperonin Cpn60, conserved site [IPR018370]", "Chaperonin GroES, conserved site [IPR018369]", "Chaperonin TCP-1, conserved site [IPR002194]", "Chromo domain, conserved site [IPR023779]", "Clathrin adaptor complex, small chain [IPR000804]", "Clathrin adaptor, mu subunit, conserved site [IPR018240]", "Clusterin, conserved site [IPR033986]", "Coproporphyrinogen III oxidase, conserved site [IPR018375]", "Cullin, conserved site [IPR016157]", "Cyclic nucleotide-binding, conserved site [IPR018488]", "Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site [IPR020892]", "Cytochrome P450, conserved site [IPR017972]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1 [IPR029752]", "D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site [IPR029753]", "DNA ligase, ATP-dependent, conserved site [IPR016059]", "DNA methylase, C-5 cytosine-specific,  conserved site [IPR031303]", "DNA methylase, N-6 adenine-specific, conserved site [IPR002052]", "DNA mismatch repair, conserved site [IPR014762]", "DNA topoisomerase, type IIA, conserved site [IPR018522]", "DNA-directed DNA polymerase, family A, conserved site [IPR019760]", "DNA-directed DNA polymerase, family B, conserved site [IPR017964]", "DNA-directed RNA polymerase, 30-40kDa subunit, conserved site [IPR001514]", "DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site [IPR002464]", "Dihydrofolate reductase conserved site [IPR017925]", "Dihydroorotase, conserved site [IPR002195]", "DnaJ domain, conserved site [IPR018253]", "Dpy-30 motif [IPR007858]", "Dynamin, GTPase region, conserved site [IPR019762]", "Dynein light chain, type 1/2, conserved site [IPR019763]", "EGF-like calcium-binding, conserved site [IPR018097]", "EGF-like, conserved site [IPR013032]", "Electron transfer flavoprotein subunit alpha, conserved site [IPR018206]", "Electron transfer flavoprotein, beta-subunit, conserved site [IPR000049]", "Enolase, conserved site [IPR020809]", "Enoyl-CoA hydratase/isomerase, conserved site [IPR018376]", "Ependymin, conserved site [IPR018224]", "Eukaryotic translation initiation factor 4E (eIF-4E), conserved site [IPR019770]", "F-actin capping protein, alpha subunit, conserved site [IPR017865]", "F-actin capping protein, beta subunit, conserved site [IPR019771]", "FERM conserved site [IPR019747]", "FLAP/GST2/LTC4S, conserved site [IPR018295]", "Fatty acid desaturase type 1, conserved site [IPR001522]", "FeS cluster insertion, C-terminal, conserved site [IPR017870]", "Fibrillarin, conserved site [IPR020813]", "Fork head domain conserved site 2 [IPR030456]", "Fork head domain conserved site1 [IPR018122]", "Formate-tetrahydrofolate ligase, FTHFS, conserved site [IPR020628]", "Fructose-bisphosphate aldolase class-I active site [IPR029768]", "Fumarate lyase, conserved site [IPR020557]", "GHMP kinase, ATP-binding, conserved site [IPR006203]", "GTP1/OBG, conserved site [IPR006074]", "Galactokinase, conserved site [IPR019741]", "Gamma-glutamyl phosphate reductase GPR, conserved site [IPR020593]", "Glucosamine-6-phosphate isomerase, conserved site [IPR018321]", "Glutamate 5-kinase, conserved site [IPR019797]", "Glutamyl-tRNA(Gln) amidotransferase, subunit B, conserved site [IPR017958]", "Glutathione peroxidase conserved site [IPR029760]", "Glycoside hydrolase family 27/36, conserved site [IPR000111]", "Glycoside hydrolase, family 29, conserved site [IPR018526]", "Glycoside hydrolase, family 35, conserved site [IPR019801]", "Glycosyl hydrolases family 31, conserved site [IPR030459]", "Glyoxalase I, conserved site [IPR018146]", "Golgin subfamily A member 2, C-terminal binding motif [IPR043937]", "Guanine-nucleotide dissociation stimulator, CDC24, conserved site [IPR001331]", "Guanylate kinase, conserved site [IPR020590]", "HIND motif [IPR045347]", "HMG box A DNA-binding domain, conserved site [IPR017967]", "HMG-I/HMG-Y, DNA-binding, conserved site [IPR000637]", "Haem oxygenase conserved site [IPR018207]", "Heat shock protein 70, conserved site [IPR018181]", "Heat shock protein Hsp90, conserved site [IPR019805]", "Helix-hairpin-helix motif, class 2 [IPR008918]", "Hexapeptide transferase, conserved site [IPR018357]", "Histidine triad, conserved site [IPR019808]", "Histone H2A conserved site [IPR032458]", "Histone H4, conserved site [IPR019809]", "Homeobox, conserved site [IPR017970]", "IMP dehydrogenase / GMP reductase, conserved site [IPR015875]", "Immunoglobulin/major histocompatibility complex, conserved site [IPR003006]", "Inositol monophosphatase, conserved site [IPR020550]", "Intermediate filament protein, conserved site [IPR018039]", "Isocitrate/isopropylmalate dehydrogenase, conserved site [IPR019818]", "Kank N-terminal motif [IPR021939]", "Kinesin motor domain, conserved site [IPR019821]", "Lipocalin family conserved site [IPR022272]", "Low-density lipoprotein (LDL) receptor class A, conserved site [IPR023415]", "Lysophospholipase patatin, conserved site [IPR001423]", "Lysosome-associated membrane glycoprotein, conserved site [IPR018134]", "Macrophage migration inhibitory factor, conserved site [IPR019829]", "Malic enzyme, conserved site [IPR015884]", "Methylthiotransferase, conserved site [IPR020612]", "Mini-chromosome maintenance, conserved site [IPR018525]", "Mitogen-activated protein (MAP) kinase, conserved site [IPR003527]", "MnmG-related, conserved site [IPR020595]", "MoaA/NifB/PqqE, iron-sulphur binding, conserved site [IPR000385]", "Molybdenum cofactor biosynthesis, conserved site [IPR008284]", "Mrp, conserved site [IPR000808]", "Myristoyl-CoA:protein N-myristoyltransferase, conserved site [IPR022678]", "NADH:ubiquinone oxidoreductase, 30kDa subunit, conserved site [IPR020396]", "NADH:ubiquinone oxidoreductase, 49kDa subunit, conserved site [IPR014029]", "NADH:ubiquinone oxidoreductase, 51kDa subunit, conserved site [IPR001949]", "NADH:ubiquinone oxidoreductase, 75kDa subunit, conserved site [IPR000283]", "NADH:ubiquinone oxidoreductase, subunit 1, conserved site [IPR018086]", "NUDIX hydrolase, conserved site [IPR020084]", "Oxysterol-binding protein, conserved site [IPR018494]", "P-type trefoil, conserved site [IPR017957]", "Peptidase M24B, X-Pro dipeptidase/aminopeptidase P, conserved site [IPR001131]", "Peptidase S26A, signal peptidase I, conserved site [IPR019758]", "Phosphatidylethanolamine-binding, conserved site [IPR001858]", "Phosphatidylinositol 3/4-kinase, conserved site [IPR018936]", "Phosphoenolpyruvate carboxykinase, GTP-utilising, conserved site [IPR018091]", "Phosphofructokinase, conserved site [IPR015912]", "Phosphoglucose isomerase, conserved site [IPR018189]", "Phosphoglycerate kinase, conserved site [IPR015911]", "Phosphomannose isomerase, type I, conserved site [IPR018050]", "Phosphoribosylglycinamide synthetase, conserved site [IPR020559]", "Phosphorylase pyridoxal-phosphate attachment site [IPR035090]", "Polyamine biosynthesis domain, conserved site [IPR030373]", "Polyprenyl synthetase, conserved site [IPR033749]", "Procollagen-lysine 5-dioxygenase, conserved site [IPR001006]", "Profilin conserved site [IPR027310]", "Proliferating cell nuclear antigen, PCNA, conserved site [IPR022659]", "Proteasome beta-type subunit, conserved site [IPR016050]", "Protein phosphatase 2A regulatory subunit PR55, conserved site [IPR018067]", "Proteinase inhibitor I2, Kunitz, conserved site [IPR020901]", "Proteinase inhibitor I25, cystatin, conserved site [IPR018073]", "Pseudouridine synthase TruD, conserved site [IPR020119]", "Purine phosphorylase, family 2, conserved site [IPR018099]", "Quinone oxidoreductase/zeta-crystallin, conserved site [IPR002364]", "RIO kinase, conserved site [IPR018935]", "RNA 3'-terminal phosphate cyclase-like, conserved site [IPR020719]", "RNA polymerase, beta subunit, conserved site [IPR007121]", "RNA polymerase, subunit H/Rpb5, conserved site [IPR020608]", "Ras GTPase-activating protein, conserved site [IPR023152]", "Rel homology domain, conserved site [IPR030492]", "Retro-transposon transporting motif [IPR018892]", "Ribonuclease II/R, conserved site [IPR022966]", "Ribosomal RNA adenine methylase transferase, conserved site [IPR020596]", "Ribosomal S11, conserved site [IPR018102]", "Ribosomal S24e conserved site [IPR018098]", "Ribosomal protein L1, conserved site [IPR023673]", "Ribosomal protein L10e, conserved site [IPR018255]", "Ribosomal protein L11, conserved site [IPR020785]", "Ribosomal protein L13, conserved site [IPR023563]", "Ribosomal protein L13e, conserved site [IPR018256]", "Ribosomal protein L14P,  conserved site [IPR019972]", "Ribosomal protein L15, conserved site [IPR001196]", "Ribosomal protein L15e, conserved site [IPR020925]", "Ribosomal protein L18e, conserved site [IPR021132]", "Ribosomal protein L19/L19e conserved site [IPR023638]", "Ribosomal protein L2, conserved site [IPR022671]", "Ribosomal protein L21e, conserved site [IPR018259]", "Ribosomal protein L22/L17, conserved site [IPR018260]", "Ribosomal protein L23/L25, conserved site [IPR001014]", "Ribosomal protein L24/L26, conserved site [IPR005825]", "Ribosomal protein L24e, conserved site [IPR023442]", "Ribosomal protein L27e, conserved site [IPR018262]", "Ribosomal protein L29, conserved site [IPR018254]", "Ribosomal protein L3, conserved site [IPR019926]", "Ribosomal protein L30, conserved site [IPR018038]", "Ribosomal protein L30e, conserved site [IPR022991]", "Ribosomal protein L31e, conserved site [IPR020052]", "Ribosomal protein L32e, conserved site [IPR018263]", "Ribosomal protein L34e, conserved site [IPR018065]", "Ribosomal protein L35Ae, conserved site [IPR018266]", "Ribosomal protein L37e, conserved site [IPR018267]", "Ribosomal protein L4/L1e, eukaryotic/archaeal, conserved site [IPR013000]", "Ribosomal protein L5, conserved site [IPR020929]", "Ribosomal protein L6, conserved site-2 [IPR002359]", "Ribosomal protein L7Ae conserved site [IPR004037]", "Ribosomal protein S10, conserved site [IPR018268]", "Ribosomal protein S13, conserved site [IPR018269]", "Ribosomal protein S17, conserved site [IPR019979]", "Ribosomal protein S17e, conserved site [IPR018273]", "Ribosomal protein S19 conserved site [IPR020934]", "Ribosomal protein S19e, conserved site [IPR018277]", "Ribosomal protein S2, conserved site [IPR018130]", "Ribosomal protein S21e, conserved site [IPR018279]", "Ribosomal protein S28e conserved site [IPR028626]", "Ribosomal protein S3, conserved site [IPR018280]", "Ribosomal protein S3Ae, conserved site [IPR018281]", "Ribosomal protein S4, conserved site [IPR018079]", "Ribosomal protein S4e, N-terminal, conserved site [IPR018199]", "Ribosomal protein S5, N-terminal, conserved site [IPR018192]", "Ribosomal protein S6e, conserved site [IPR018282]", "Ribosomal protein S7, conserved site [IPR020606]", "Ribosomal protein S8e, conserved site [IPR018283]", "Ribosomal protein S9, conserved site [IPR020574]", "Ribosome maturation protein SBDS, conserved site [IPR018023]", "Ribosome-binding factor A, conserved site [IPR020053]", "RidA, conserved site [IPR019897]", "S-adenosyl-L-homocysteine hydrolase, conserved site [IPR020082]", "S-adenosylmethionine synthetase, conserved site [IPR022631]", "S100/Calbindin-D9k, conserved site [IPR001751]", "SAICAR synthetase, conserved site [IPR018236]", "SecY conserved site [IPR030659]", "Serpin, conserved site [IPR023795]", "Short-chain dehydrogenase/reductase, conserved site [IPR020904]", "Sodium:dicarboxylate symporter, conserved site [IPR018107]", "Squalene/phytoene synthase, conserved site [IPR019845]", "Stathmin, conserved site [IPR030514]", "Sterol reductase, conserved site [IPR018083]", "Succinate dehydrogenase, cytochrome b subunit, conserved site [IPR018495]", "Succinyl-CoA synthetase, beta subunit, conserved site [IPR017866]", "Sugar transporter, conserved site [IPR005829]", "Sulfatase, conserved site [IPR024607]", "Syntaxin/epimorphin, conserved site [IPR006012]", "TPP-binding enzyme, conserved site [IPR000399]", "Terpene synthase, conserved site [IPR002365]", "Tetrahydrofolate dehydrogenase/cyclohydrolase, conserved site [IPR020867]", "Tetraspanin, conserved site [IPR018503]", "Thiolase, conserved site [IPR020613]", "Thioredoxin, conserved site [IPR017937]", "Thiosulphate sulfurtransferase, conserved site [IPR001307]", "Thymidine kinase, conserved site [IPR020633]", "Thymidylate kinase, conserved site [IPR018095]", "Tr-type G domain, conserved site [IPR031157]", "Transcription factor TFIIB, conserved site [IPR023486]", "Translation elongation factor EF1B, beta/delta chains, conserved site [IPR001326]", "Translation elongation factor Ts, conserved site [IPR018101]", "Translationally controlled tumour protein, conserved site [IPR018103]", "Tubulin, conserved site [IPR017975]", "Tyrosine-protein kinase, receptor class V, conserved site [IPR001426]", "UbiE/COQ5 methyltransferase, conserved site [IPR023576]", "Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site [IPR018168]", "Ubiquitin conserved site [IPR019954]", "Ubiquitin interacting motif [IPR003903]", "Ubiquitin specific protease, conserved site [IPR018200]", "Ubiquitin-activating enzyme E1, conserved site [IPR018074]", "Vinculin, conserved site [IPR000633]", "WD40 repeat, conserved site [IPR019775]", "XPG conserved site [IPR019974]", "YgfZ/GcvT conserved site [IPR017703]", "Zinc finger, PHD-type, conserved site [IPR019786]", "Zinc finger, RING-type, conserved site [IPR017907]", "tRNA-dihydrouridine synthase, conserved site [IPR018517]"], "available_proteins": ["AAAS", "AAMP", "ABCB1", "ABCB10", "ABCB7", "ABCB8", "ABCC1", "ABCD3", "ABCE1", "ABCF1", "ABCF2", "ABCF3", "ABR", "ACAA1", "ACAA2", "ACAD9", "ACADM", "ACADS", "ACADSB", "ACADVL", "ACAT1", "ACAT2", "ACBD3", "ACIN1", "ACLY", "ACSF3", "ACSL1", "ACSL3", "ACSL4", "ACSL6", "ACTL6A", "ACTN1", "ACTN4", "ACTR1A", "ACTR2", "ACTR3", "ADH5", "ADK", "ADSL", "AFG3L2", "AHCY", "AHCYL1", "AK1", "AK2", "AK4", "AKR1A1", "AKR1B1", "ALDH18A1", "ALDH1B1", "ALDH2", "ALDH3A2", "ALDH4A1", "ALDH5A1", "ALDH6A1", "ALDH7A1", "ALDH9A1", "ALDOA", "ALDOC", "ANXA1", "ANXA11", "ANXA2", "ANXA4", "ANXA6", "ANXA7", "AP1M1", "AP1S1", "AP2M1", "AP2S1", "AP3M1", "APEX1", "APP", "ARHGEF7", "ARIH2", "ARRB2", "ATAD1", "ATAD2", "ATM", "ATP5C1", "ATP5O", "BAG6", "BAK1", "BARD1", "BAZ1A", "BAZ1B", "BCAT2", "BCR", "BCS1L", "BLM", "BOP1", "BPNT1", "BPTF", "BRCA1", "BRD2", "BUD31", "CAD", "CALR", "CAMSAP3", "CANX", "CAP1", "CAPZA1", "CAPZA2", "CAPZB", "CASK", "CBL", "CBR1", "CBX1", "CBX3", "CBX5", "CBX8", "CCT2", "CCT3", "CCT4", "CCT5", "CCT6A", "CCT7", "CCT8", "CDC40", "CDH2", "CDK5RAP1", "CDKAL1", "CETN2", "CHAF1B", "CHD1", "CHD1L", "CHD3", "CHD4", "CLU", "CMPK1", "CNDP2", "COLEC12", "COPA", "COPZ1", "COQ6", "CORO1B", "CORO1C", "CORO7", "CPOX", "CRYZ", "CSTB", "CSTF1", "CTBP1", "CTBP2", "CTNNA1", "CUL1", "CUL2", "CUL3", "CUL4B", "CUL5", "CYP51A1", "DCAF13", "DCAF7", "DCPS", "DCXR", "DDT", "DDX10", "DDX17", "DDX18", "DDX20", "DDX23", "DDX24", "DDX27", "DDX3X", "DDX42", "DDX46", "DDX47", "DDX49", "DDX5", "DDX51", "DDX54", "DDX55", "DDX6", "DHCR7", "DHFR", "DHRS7", "DHRS7B", "DHX15", "DHX16", "DHX29", "DHX30", "DHX36", "DHX38", "DHX40", "DHX57", "DHX8", "DHX9", "DIDO1", "DIMT1", "DIS3", "DLG1", "DNAJA1", "DNAJA2", "DNAJA3", "DNAJB1", "DNAJB11", "DNAJB4", "DNAJC1", "DNAJC10", "DNAJC11", "DNAJC16", "DNAJC2", "DNAJC9", "DNM1L", "DNM2", "DNMT1", "DPY30", "DRG1", "DRG2", "DSC3", "DSG2", "DTL", "DTYMK", "DUS2", "DUS3L", "DYNLL1", "DYNLL2", "EARS2", "ECH1", "ECHDC1", "ECHS1", "ECI1", "ECI2", "EED", "EEF1A2", "EEF1B2", "EEF1D", "EEF2", "EIF3I", "EIF4A1", "EIF4A2", "EIF4A3", "EIF4E2", "ENO1", "ENO2", "EPB41", "EPB41L2", "EPB41L3", "EPB41L5", "EPDR1", "EPHA2", "EPHA7", "EPN1", "EPRS", "EPS15", "ERCC2", "ETFA", "ETFB", "EXO1", "EZR", "FARP1", "FBL", "FBXW11", "FDFT1", "FDPS", "FEN1", "FH", "FLNA", "FLNB", "FLNC", "FOXK1", "FOXK2", "FUCA1", "FUCA2", "GAA", "GALK1", "GALM", "GANAB", "GART", "GATB", "GCDH", "GEMIN5", "GFM1", "GLA", "GLB1", "GLO1", "GMPPA", "GNB1", "GNPDA1", "GNS", "GOLGA2", "GPHN", "GPI", "GPX8", "GRHPR", "GRWD1", "GSPT1", "GTF2B", "GTF3C2", "GUF1", "H2AFX", "H4C1*", "HADH", "HADHA", "HADHB", "HGS", "HIBADH", "HINT2", "HLA-A", "HLTF", "HMGA1", "HMGB1", "HMGB2", "HMGB3", "HMOX1", "HMOX2", "HOXA10", "HSD17B10", "HSD17B12", "HSD17B4", "HSD17B8", "HSDL2", "HSP90AA1", "HSP90AB1", "HSP90B1", "HSPA14", "HSPA1B", "HSPA2", "HSPA4", "HSPA4L", "HSPA8", "HSPA9", "HSPD1", "HSPE1", "HSPH1", "HYOU1", "IARS", "IARS2", "IBA57", "IDH1", "IDH2", "IDH3A", "IDH3B", "ILVBL", "IMPAD1", "IMPDH1", "IMPDH2", "INA", "ING5", "IQGAP1", "IQGAP2", "IQGAP3", "ISCA2", "IVD", "KANK2", "KDM2A", "KDSR", "KIF11", "KIF14", "KIF1A", "KIF20A", "KIF22", "KIF23", "KIF2A", "KIF2C", "KIF3A", "KIF4A", "KIF5B", "KIF7", "KIFC1", "LAMP1", "LARS", "LARS2", "LBR", "LDLR", "LIG1", "LIG3", "LMNA", "LMNB1", "LMNB2", "LRP1", "LRWD1", "LSS", "MACF1", "MAGI3", "MAPK1", "MAPK14", "MAPK3", "MARS", "MAT2A", "MCL1", "MCM2", "MCM3", "MCM4", "MCM5", "MCM6", "MCM7", "ME1", "ME2", "MGST2", "MID1", "MIF", "MKRN2", "MOCS1", "MPI", "MPP1", "MPP2", "MPP6", "MPST", "MRC2", "MRPL13", "MRPL3", "MRPS11", "MRPS2", "MRPS5", "MRPS9", "MSN", "MTAP", "MTHFD1", "MTHFD1L", "MTHFD2", "MTO1", "MTOR", "ND1", "NDUFS1", "NDUFS2", "NDUFS3", "NDUFS8", "NDUFV1", "NEFL", "NEFM", "NES", "NET1", "NF1", "NKTR", "NLE1", "NMT1", "NMT2", "NNT", "NOP2", "NOTCH2", "NSD1", "NSD2", "NSD3", "NSF", "NUBP2", "NUDT1", "NUDT5", "NUP153", "NUP37", "NUP43", "NVL", "OAS3", "OSBP", "OSBPL11", "OSBPL3", "OSBPL8", "OSBPL9", "P4HB", "PAFAH1B1", "PAICS", "PAK1IP1", "PBRM1", "PCK2", "PCNA", "PDIA3", "PDIA4", "PDIA6", "PEBP1", "PEPD", "PFKL", "PFKM", "PFKP", "PFN1", "PFN2", "PGK1", "PGM1", "PGM2", "PGM3", "PHF3", "PHF8", "PHGDH", "PHIP", "PI4KA", "PI4KB", "PIK3C2A", "PLEC", "PLOD1", "PLOD2", "PLOD3", "PLRG1", "PLS1", "PLS3", "PMS1", "PNP", "PNPLA6", "POLA1", "POLD1", "POLG", "POLR1B", "POLR1C", "POLR2B", "POLR2C", "POLR2E", "POLR3B", "PPIB", "PPIC", "PPID", "PPIE", "PPIF", "PPIH", "PPIL1", "PPIL2", "PPIL3", "PPP2R2A", "PRKAR1A", "PRKAR2A", "PRKDC", "PRPF19", "PRPF4", "PSMA4", "PSMB1", "PSMB2", "PSMB3", "PSMB4", "PSMB5", "PSMB6", "PSMB7", "PSMC1", "PSMC2", "PSMC3", "PSMC4", "PSMC5", "PSMC6", "PSMD4", "PUS7", "PWP1", "PWP2", "PYGB", "PYGL", "QARS", "QDPR", "RACK1", "RAE1", "RANBP2", "RARS", "RARS2", "RBBP4", "RBFA", "RCL1", "RDH13", "RDX", "RECQL5", "RELA", "RIDA", "RIOK2", "RNF114", "RNF20", "RNF40", "RPL10", "RPL10A", "RPL11", "RPL12", "RPL13", "RPL13A", "RPL15", "RPL17", "RPL18", "RPL19", "RPL21", "RPL23", "RPL23A", "RPL24", "RPL26", "RPL27", "RPL27A", "RPL3", "RPL30", "RPL31", "RPL32", "RPL34", "RPL35", "RPL35A", "RPL37", "RPL4", "RPL7", "RPL7A", "RPL7L1", "RPL8", "RPL9", "RPS11", "RPS14", "RPS15", "RPS16", "RPS17", "RPS18", "RPS19", "RPS2", "RPS20", "RPS21", "RPS24", "RPS28", "RPS3", "RPS3A", "RPS4X", "RPS5", "RPS6", "RPS8", "RPS9", "RPSA", "RRP8", "RRP9", "RSF1", "RTCA", "S100A11", "SART1", "SBDS", "SCAF11", "SCD", "SCP2", "SDHB", "SDHC", "SEC11A", "SEC61A1", "SERPINB1", "SERPINB6", "SERPINH1", "SH3RF1", "SLC1A5", "SLC25A42", "SLC27A2", "SLC27A4", "SLC2A1", "SLIT2", "SMARCA4", "SMG1", "SMS", "SMU1", "SNRNP40", "SNU13", "SORD", "SPATA5", "SPATA5L1", "SPTBN1", "SPTBN2", "SRCAP", "SRM", "STAM", "STMN1", "STOM", "STRN", "STX10", "STX12", "STX18", "STX5", "STX7", "SUCLA2", "SUCLG1", "SUCLG2", "SV2A", "SYNE2", "TAF5L", "TAP2", "TBL1XR1", "TBL3", "TCP1", "TFB1M", "THOC6", "TK1", "TLE3", "TLN1", "TM7SF2", "TMX1", "TMX4", "TOP2A", "TOP2B", "TPT1", "TRAF2", "TRIM21", "TRIM24", "TRIM25", "TRIM28", "TRIM32", "TRIM33", "TRIP13", "TRMT11", "TSFM", "TSPAN6", "TTF2", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TUBB6", "TUFM", "TXNDC12", "TXNDC5", "TXNL1", "UBA1", "UBA2", "UHRF1", "USP1", "USP10", "USP11", "USP14", "USP19", "USP24", "USP28", "USP34", "USP38", "USP47", "USP48", "USP5", "USP7", "USP8", "USP9X", "UTP15", "UTP18", "UTRN", "VARS1", "VARS2", "VAT1", "VAV2", "VCL", "VCP", "VIM", "VPS4A", "VPS4B", "WARS", "WDHD1", "WDR1", "WDR11", "WDR12", "WDR18", "WDR3", "WDR36", "WDR41", "WDR5", "WDR55", "WDR61", "WDR77", "WDR83", "XPNPEP1", "YARS2", "YME1L1", "YWHAB", "YWHAE", "YWHAG", "YWHAH", "YWHAQ", "YWHAZ", "ZADH2"], "leading_proteins": ["ABCB1", "ABCD3", "AP1M1", "ARHGEF7", "BCR", "CCT2", "CCT3", "DHRS7", "DNAJC1", "DNAJC16", "DNM1L", "DRG2", "GAA", "HADHA", "HMGB2", "HMGB3", "HMOX1", "HSD17B12", "IQGAP1", "IQGAP3", "KDSR", "LBR", "MAPK14", "MAPK3", "MCM6", "MTOR", "NET1", "NF1", "P4HB", "PFKL", "PFKM", "PFN2", "PI4KB", "PSMB2", "RDH13", "SLC25A42", "SRM", "STX10", "STX18", "STX5", "TAP2", "TM7SF2", "TMX1", "TMX4", "TUBB", "TUBB2A", "TUBB2B", "TUBB4A", "TUBB4B", "TXNDC12", "VAV2", "YWHAB", "YWHAE", "YWHAG", "YWHAQ", "YWHAZ"]}

interpro_domain/advanced/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin/FtsZ, GTPase domain [IPR003008]", "1": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "2": "P-type ATPase, haloacid dehalogenase domain [IPR044492]"}

interpro_domain/basic/idx2term.json

@@ -0,0 +1 @@
+{"0": "Tubulin/FtsZ, GTPase domain [IPR003008]", "1": "Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]", "2": "P-type ATPase, haloacid dehalogenase domain [IPR044492]", "3": "Dynamin-type guanine nucleotide-binding (G) domain [IPR030381]", "4": "Dynamin, N-terminal [IPR045063]", "5": "EF-hand domain [IPR002048]", "6": "JAB1/MPN/MOV34 metalloenzyme domain [IPR000555]", "7": "Thioredoxin domain [IPR013766]", "8": "MPN domain [IPR037518]", "9": "Proteasome component (PCI) domain [IPR000717]", "10": "TGS [IPR004095]", "11": "14-3-3 domain [IPR023410]"}

interpro_domain/consensus.joblib

@@ -0,0 +1,3 @@
+version https://git-lfs.github.com/spec/v1
+oid sha256:b0489b67e5bdc67066ae3b850c79d4533cbf746dc9c98a04d1dfbf0935a1b8fa
+size 179747

interpro_domain/df_merge.tsv

@@ -0,0 +1,9 @@
+term	overlap	setsize	score	pval	overlap_mean	setsize_mean	score_mean	pval_mean	overlap_std	setsize_std	score_std	pval_std	pval_hit	pval_50	pval_100	pval_250	pval_500
+Tubulin/FtsZ, GTPase domain [IPR003008]	5	6	2.686227661162481	0.0072263831966969	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	3.5046047927792675e-08	7.603990755252932e-05	5.456750888757529e-07	2.6381727410940915e-06	0.0001398239466262
+Tubulin/FtsZ, 2-layer sandwich domain [IPR018316]	5	6	2.686227661162481	0.0072263831966969	3.6140776699029127	5.883495145631068	0.537603280896448	0.3771225437200781	1.6631634011190108	1.117390952728082	1.2199662970774952	0.3090115161057067	2.3585955312798212e-08	6.357667188483331e-05	3.970810735588237e-07	1.7947231953922547e-06	9.715916455054114e-05
+P-type ATPase, haloacid dehalogenase domain [IPR044492]	5	6	2.2302753341792623	0.0257291696460577	2.941747572815534	6.145631067961165	0.9567723497044874	0.2732808833570771	1.8358630293390923	1.459204245106796	1.2102525517005158	0.2943240638910574	0.2261367374172987	1.0	1.0	0.0150601402708497	0.0004763398606397
+Cytochrome b5-like heme/steroid binding domain [IPR001199]	2	5	2.1943890720751296	0.0282074508516152	2.813106796116505	6.104368932038835	1.6405397264547834	0.1100883340733615	1.2852875686886795	0.8042848477475721	1.100790504333474	0.1612592696854457	0.0081255985064357	0.0013899505248691	0.0055563644779973	0.0025675639060761	0.0178266474623968
+Cation-transporting P-type ATPase, C-terminal [IPR006068]	4	5	2.172589952288544	0.0298111927909623	2.2985436893203883	4.150485436893204	0.5310155053290574	0.3897464493012307	1.1928988171245156	0.7984662222288074	1.1360507856968378	0.3059467081218019	1.0	1.0	1.0	0.0227865880642579	5.331497427737023e-05
+Cation-transporting P-type ATPase, N-terminal [IPR004014]	4	5	2.172589952288544	0.0298111927909623	2.2985436893203883	4.150485436893204	0.5310155053290574	0.3897464493012307	1.1928988171245156	0.7984662222288074	1.1360507856968378	0.3059467081218019	1.0	1.0	1.0	0.0227865880642579	5.331497427737023e-05
+Phospholipid/glycerol acyltransferase [IPR002123]	4	5	2.06902297524207	0.0385439307710204	2.4611650485436893	6.109223300970874	0.4541526786138767	0.3733328307275969	1.647577392422315	1.6678607828333205	1.200305691546449	0.3080828121567173	1.0	1.0	1.0	1.0	0.0393335136754485
+Major facilitator superfamily domain [IPR020846]	3	6	2.057593632161148	0.0396291584429862	1.8883495145631068	4.121359223300971	0.8776223597987594	0.2728824130413255	1.233496960525634	1.4580976091979958	1.2936014196902064	0.266909732326598	0.2951147076443046	1.0	0.2496255286594674	0.0345219152795696	0.0547141411106198

interpro_domain/metrics.json

@@ -0,0 +1,7 @@
+{
+    "type_of_task": "ranksum",
+    "signature_size": 3447,
+    "annotations_size": 2818,
+    "title": "Average number of proteins per term",
+    "value": 2.22249822569198
+}